Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000612-TA|BGIBMGA000612-PA|IPR002928|Myosin tail,
IPR009053|Prefoldin
(512 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 255 3e-67
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 255 3e-67
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 254 5e-67
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 254 5e-67
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 254 7e-67
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 254 7e-67
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 254 7e-67
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 254 7e-67
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 254 7e-67
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 253 1e-66
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 249 2e-65
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 249 2e-65
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 248 3e-65
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 248 3e-65
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 248 4e-65
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 248 4e-65
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 248 5e-65
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 245 3e-64
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 245 3e-64
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 245 3e-64
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 245 3e-64
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 245 3e-64
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 242 2e-63
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 241 3e-63
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 241 3e-63
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 238 4e-62
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 235 2e-61
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 235 2e-61
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 235 2e-61
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 235 2e-61
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 230 1e-59
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 226 1e-58
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 216 1e-55
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 187 7e-47
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 150 1e-35
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 150 1e-35
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 150 1e-35
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 148 5e-35
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 148 5e-35
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 148 5e-35
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 146 1e-34
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 143 2e-33
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 141 6e-33
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 141 6e-33
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 141 6e-33
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 141 6e-33
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 141 6e-33
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 141 6e-33
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 141 6e-33
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 141 6e-33
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 121 7e-27
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 121 7e-27
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 117 9e-26
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 113 1e-24
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 109 2e-23
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 88 6e-17
BC022376-1|AAH22376.1| 627|Homo sapiens Unknown (protein for IM... 88 8e-17
X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (... 84 1e-15
M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac m... 84 1e-15
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 82 4e-15
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 81 1e-14
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 65 5e-10
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 65 5e-10
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 65 5e-10
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 65 5e-10
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 65 5e-10
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 64 8e-10
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 64 8e-10
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 64 1e-09
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 64 1e-09
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 64 1e-09
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 64 1e-09
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 64 1e-09
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 62 3e-09
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 62 3e-09
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 62 3e-09
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 62 3e-09
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 62 3e-09
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 62 3e-09
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 62 3e-09
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 62 3e-09
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 62 3e-09
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 62 3e-09
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 62 3e-09
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 62 3e-09
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 62 3e-09
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 62 3e-09
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 62 3e-09
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 62 5e-09
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 61 8e-09
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 61 8e-09
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 61 8e-09
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 61 8e-09
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 61 8e-09
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 61 8e-09
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 61 8e-09
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 61 1e-08
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 61 1e-08
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 61 1e-08
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 61 1e-08
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 60 2e-08
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 60 2e-08
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 60 2e-08
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 59 3e-08
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 59 3e-08
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 59 3e-08
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 59 3e-08
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 59 4e-08
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 59 4e-08
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 58 7e-08
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 58 7e-08
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 58 7e-08
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 58 7e-08
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 58 7e-08
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 58 7e-08
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 58 1e-07
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 58 1e-07
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 58 1e-07
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 58 1e-07
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 57 2e-07
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 57 2e-07
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 57 2e-07
AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein. 57 2e-07
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 56 2e-07
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 56 3e-07
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 55 5e-07
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 55 5e-07
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 54 9e-07
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 54 1e-06
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 54 2e-06
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 54 2e-06
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 53 2e-06
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 53 2e-06
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 53 2e-06
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 53 2e-06
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 53 2e-06
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 53 3e-06
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 53 3e-06
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 53 3e-06
AK057222-1|BAB71385.1| 740|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 53 3e-06
AC093378-1|AAY15082.1| 659|Homo sapiens unknown protein. 53 3e-06
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 52 4e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 52 4e-06
AK001254-1|BAA91584.1| 636|Homo sapiens protein ( Homo sapiens ... 52 4e-06
AB033038-1|BAA86526.2| 802|Homo sapiens KIAA1212 protein protein. 52 4e-06
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 52 5e-06
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 52 5e-06
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 52 6e-06
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 52 6e-06
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 52 6e-06
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 52 6e-06
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 52 6e-06
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 52 6e-06
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 52 6e-06
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 52 6e-06
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 52 6e-06
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 52 6e-06
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 52 6e-06
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 52 6e-06
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 52 6e-06
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 52 6e-06
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 52 6e-06
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 52 6e-06
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 51 8e-06
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 51 8e-06
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 51 8e-06
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 51 8e-06
AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein pro... 51 8e-06
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 51 8e-06
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 51 8e-06
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 51 8e-06
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 51 8e-06
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 51 8e-06
AK002047-1|BAA92054.1| 422|Homo sapiens protein ( Homo sapiens ... 51 8e-06
AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain prot... 51 8e-06
AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain prot... 51 8e-06
AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein. 51 8e-06
AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein. 51 8e-06
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 51 8e-06
BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein. 51 1e-05
AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor... 51 1e-05
AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein. 51 1e-05
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 50 1e-05
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 50 1e-05
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 50 1e-05
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 50 1e-05
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 50 1e-05
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 50 1e-05
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 50 1e-05
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 50 1e-05
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 50 2e-05
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 50 3e-05
X97053-1|CAA65765.1| 566|Homo sapiens plectin protein. 49 3e-05
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 49 3e-05
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 49 3e-05
Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein. 49 5e-05
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 49 5e-05
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 49 5e-05
M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein. 49 5e-05
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 49 5e-05
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 49 5e-05
BC133019-1|AAI33020.1| 1427|Homo sapiens LOC650001 protein protein. 49 5e-05
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 49 5e-05
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 49 5e-05
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 49 5e-05
BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein. 49 5e-05
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 49 5e-05
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 49 5e-05
AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymph... 49 5e-05
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 49 5e-05
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 49 5e-05
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 49 5e-05
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 49 5e-05
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 48 6e-05
X14487-1|CAA32649.1| 593|Homo sapiens protein ( Human gene for ... 48 6e-05
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 48 6e-05
J04029-1|AAA60544.1| 561|Homo sapiens keratin 10 protein. 48 6e-05
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 48 6e-05
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 48 6e-05
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 48 6e-05
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 48 6e-05
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 48 6e-05
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 48 6e-05
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 48 8e-05
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 48 8e-05
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 48 8e-05
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 48 1e-04
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 48 1e-04
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 48 1e-04
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 48 1e-04
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 48 1e-04
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ... 48 1e-04
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 48 1e-04
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 48 1e-04
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 48 1e-04
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 48 1e-04
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 48 1e-04
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 48 1e-04
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 48 1e-04
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ... 48 1e-04
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 48 1e-04
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 48 1e-04
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 48 1e-04
AF161352-1|AAF28912.1| 290|Homo sapiens HSPC089 protein. 48 1e-04
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 48 1e-04
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 48 1e-04
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 48 1e-04
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p... 48 1e-04
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 48 1e-04
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 48 1e-04
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 47 1e-04
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 47 1e-04
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 47 1e-04
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 47 1e-04
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 47 1e-04
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 47 1e-04
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 47 1e-04
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 47 1e-04
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 47 1e-04
BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting p... 47 1e-04
BC016175-1|AAH16175.1| 279|Homo sapiens Unknown (protein for IM... 47 1e-04
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 47 1e-04
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 47 1e-04
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 47 1e-04
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 47 1e-04
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 47 1e-04
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 47 1e-04
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein. 47 1e-04
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 47 1e-04
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 47 1e-04
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 47 1e-04
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 47 1e-04
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 47 1e-04
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 47 1e-04
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 47 1e-04
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 47 1e-04
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 47 1e-04
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 47 1e-04
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 47 2e-04
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 47 2e-04
BC131515-1|AAI31516.1| 632|Homo sapiens GOLGA6 protein protein. 47 2e-04
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 47 2e-04
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 47 2e-04
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 47 2e-04
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 47 2e-04
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 47 2e-04
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 47 2e-04
BC030505-1|AAH30505.1| 302|Homo sapiens HMMR protein protein. 47 2e-04
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 47 2e-04
BC022229-1|AAH22229.1| 229|Homo sapiens Unknown (protein for IM... 47 2e-04
BC017793-1|AAH17793.1| 331|Homo sapiens Unknown (protein for IM... 47 2e-04
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 47 2e-04
AF266285-1|AAF72535.1| 693|Homo sapiens golgin-like protein pro... 47 2e-04
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 47 2e-04
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 47 2e-04
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 47 2e-04
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 47 2e-04
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 46 2e-04
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 46 2e-04
D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin h... 46 2e-04
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 46 2e-04
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 46 2e-04
BC041070-1|AAH41070.1| 436|Homo sapiens keratin 34 protein. 46 2e-04
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 46 2e-04
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 46 2e-04
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 46 2e-04
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 46 2e-04
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 46 2e-04
BC000322-1|AAH00322.1| 1193|Homo sapiens sperm associated antige... 46 3e-04
AL137585-1|CAB70827.1| 1027|Homo sapiens hypothetical protein pr... 46 3e-04
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 46 3e-04
AF399910-1|AAK91712.1| 1193|Homo sapiens mitotic spindle associa... 46 3e-04
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 46 3e-04
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 46 4e-04
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 46 4e-04
BC016029-1|AAH16029.1| 639|Homo sapiens CTTNBP2 N-terminal like... 46 4e-04
AY166853-1|AAO17292.1| 1317|Homo sapiens kinesin motor protein p... 46 4e-04
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
AL354760-2|CAI22308.1| 639|Homo sapiens novel protein protein. 46 4e-04
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 46 4e-04
AL118509-3|CAI43063.2| 1392|Homo sapiens chromosome 20 open read... 46 4e-04
AL118509-2|CAM28305.1| 1317|Homo sapiens chromosome 20 open read... 46 4e-04
AL117376-3|CAI43180.2| 1392|Homo sapiens chromosome 20 open read... 46 4e-04
AL117376-2|CAI43181.2| 1317|Homo sapiens chromosome 20 open read... 46 4e-04
AL049794-2|CAI22745.2| 1392|Homo sapiens chromosome 20 open read... 46 4e-04
AL049794-1|CAM28307.1| 1317|Homo sapiens chromosome 20 open read... 46 4e-04
AK000142-1|BAA90971.1| 752|Homo sapiens protein ( Homo sapiens ... 46 4e-04
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 46 4e-04
AB046810-1|BAB13416.2| 1393|Homo sapiens KIAA1590 protein protein. 46 4e-04
AB037854-1|BAA92671.1| 652|Homo sapiens KIAA1433 protein protein. 46 4e-04
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 46 4e-04
M77663-1|AAA59199.1| 384|Homo sapiens keratin 10 protein. 45 6e-04
EF199840-1|ABM90426.1| 508|Homo sapiens erasin protein. 45 6e-04
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 45 6e-04
D87684-1|BAA13437.1| 529|Homo sapiens KIAA0242 protein protein. 45 6e-04
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 45 6e-04
BC035594-1|AAH35594.1| 508|Homo sapiens UBXD2 protein protein. 45 6e-04
BC034697-1|AAH34697.1| 584|Homo sapiens keratin 10 (epidermolyt... 45 6e-04
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 45 6e-04
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 45 6e-04
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 45 6e-04
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 45 6e-04
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 45 6e-04
AC011893-2|AAX88923.1| 508|Homo sapiens unknown protein. 45 6e-04
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 45 6e-04
Y16792-1|CAA76388.1| 467|Homo sapiens type I hair keratin 6 pro... 45 7e-04
L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein. 45 7e-04
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 45 7e-04
BC089400-1|AAH89400.1| 773|Homo sapiens MAP7D2 protein protein. 45 7e-04
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 45 7e-04
BC043581-1|AAH43581.1| 417|Homo sapiens KRT36 protein protein. 45 7e-04
BC037165-1|AAH37165.1| 660|Homo sapiens MAP7D2 protein protein. 45 7e-04
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 45 7e-04
AL732366-3|CAI40549.1| 732|Homo sapiens novel protein protein. 45 7e-04
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 45 7e-04
AL354760-1|CAI22307.1| 271|Homo sapiens novel protein protein. 45 7e-04
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 45 7e-04
AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein. 45 7e-04
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 45 7e-04
AK027409-1|BAB55093.1| 732|Homo sapiens protein ( Homo sapiens ... 45 7e-04
AB209992-1|BAE06074.1| 2319|Homo sapiens DSP variant protein pro... 45 7e-04
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 45 7e-04
AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein. 45 7e-04
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 44 0.001
BC141866-1|AAI41867.1| 1240|Homo sapiens Unknown (protein for IM... 44 0.001
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 44 0.001
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 44 0.001
BC053545-1|AAH53545.1| 245|Homo sapiens tropomyosin 1 (alpha) p... 44 0.001
BC050473-1|AAH50473.1| 287|Homo sapiens TPM1 protein protein. 44 0.001
BC017666-1|AAH17666.1| 941|Homo sapiens Unknown (protein for IM... 44 0.001
AK223598-1|BAD97318.1| 831|Homo sapiens Angiomotin like 2 (Frag... 44 0.001
AK095289-1|BAC04523.1| 621|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK090436-1|BAC03417.1| 1041|Homo sapiens FLJ00354 protein protein. 44 0.001
AK074126-1|BAB84952.1| 677|Homo sapiens FLJ00198 protein protein. 44 0.001
AJ310550-1|CAC39247.1| 1101|Homo sapiens SMC5 protein protein. 44 0.001
AF175966-1|AAD56361.2| 569|Homo sapiens angiomotin-like protein... 44 0.001
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 44 0.001
AB023206-1|BAA76833.1| 859|Homo sapiens angiomotin like 2 protein. 44 0.001
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 44 0.001
DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein. 44 0.001
DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1 pro... 44 0.001
BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein pr... 44 0.001
BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein. 44 0.001
BC011454-1|AAH11454.1| 466|Homo sapiens AMOTL2 protein protein. 44 0.001
BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sp... 44 0.001
AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sp... 44 0.001
AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sp... 44 0.001
AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of s... 44 0.001
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 44 0.001
AB075820-1|BAB85526.1| 821|Homo sapiens KIAA1940 protein protein. 44 0.001
Y16790-1|CAA76386.1| 394|Homo sapiens type I hair keratin 4 pro... 44 0.002
BC060826-1|AAH60826.1| 843|Homo sapiens GOLGA3 protein protein. 44 0.002
AL590431-9|CAH71267.1| 248|Homo sapiens tropomyosin 3 protein. 44 0.002
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 44 0.002
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 44 0.002
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 43 0.002
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 43 0.002
BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for IM... 43 0.002
BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein. 43 0.002
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 43 0.002
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 43 0.002
BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for IM... 43 0.002
BC062543-1|AAH62543.1| 653|Homo sapiens CLIP1 protein protein. 43 0.002
BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein. 43 0.002
AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain con... 43 0.002
AL162390-1|CAH73243.1| 1101|Homo sapiens structural maintenance ... 43 0.002
AL118509-1|CAI43062.1| 185|Homo sapiens chromosome 20 open read... 43 0.002
AL117376-1|CAI43179.1| 185|Homo sapiens chromosome 20 open read... 43 0.002
AK124447-1|BAC85854.1| 434|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF310722-1|AAK17926.1| 320|Homo sapiens tropomyosin 4-anaplasti... 43 0.002
AF186109-1|AAG17014.1| 237|Homo sapiens TPM4-ALK fusion oncopro... 43 0.002
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 43 0.002
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 43 0.002
AB209041-1|BAD92278.1| 303|Homo sapiens TPM1 protein variant pr... 43 0.002
X04627-1|CAA28300.1| 258|Homo sapiens beta-myosin heavy chain p... 43 0.003
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 43 0.003
BC038225-1|AAH38225.1| 1101|Homo sapiens structural maintenance ... 43 0.003
BC036939-1|AAH36939.1| 304|Homo sapiens C14orf145 protein protein. 43 0.003
AL137265-1|CAB70664.1| 992|Homo sapiens hypothetical protein pr... 43 0.003
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK125995-1|BAC86384.1| 842|Homo sapiens protein ( Homo sapiens ... 43 0.003
AK027816-1|BAB55389.1| 436|Homo sapiens protein ( Homo sapiens ... 43 0.003
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 43 0.003
AB028975-1|BAA83004.2| 1456|Homo sapiens KIAA1052 protein protein. 43 0.003
AB011166-1|BAA25520.2| 1120|Homo sapiens KIAA0594 protein protein. 43 0.003
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 42 0.004
AL590005-2|CAI14989.1| 7543|Homo sapiens dystonin protein. 42 0.004
AL512448-1|CAI16609.1| 7543|Homo sapiens dystonin protein. 42 0.004
AL512422-2|CAI14341.1| 7543|Homo sapiens dystonin protein. 42 0.004
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 42 0.004
AL137008-2|CAI20330.1| 7543|Homo sapiens dystonin protein. 42 0.004
AL096710-3|CAI22044.1| 7543|Homo sapiens dystonin protein. 42 0.004
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 42 0.004
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 42 0.004
X90761-1|CAA62284.1| 448|Homo sapiens HHa2 hair keratin type I ... 42 0.005
X81419-1|CAA57179.1| 405|Homo sapiens hair type I acidic kerati... 42 0.005
M19156-1|AAA59468.1| 433|Homo sapiens KRT10 protein. 42 0.005
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 42 0.005
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 42 0.005
BC077721-1|AAH77721.1| 1030|Homo sapiens ARHGEF18 protein protein. 42 0.005
BC045834-1|AAH45834.2| 435|Homo sapiens C14orf145 protein protein. 42 0.005
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 42 0.005
AY422473-1|AAR13704.1| 1326|Homo sapiens myosin tail domain-cont... 42 0.005
AL662788-1|CAI95333.1| 1326|Homo sapiens chromosome 9 open readi... 42 0.005
AL592153-1|CAI95316.1| 1326|Homo sapiens chromosome 9 open readi... 42 0.005
AL590431-10|CAH71268.1| 247|Homo sapiens tropomyosin 3 protein. 42 0.005
AL359877-3|CAI94977.1| 1326|Homo sapiens chromosome 9 open readi... 42 0.005
AK127045-1|BAC86801.1| 1173|Homo sapiens HO-GEF). protein. 42 0.005
AF083811-1|AAD24498.1| 718|Homo sapiens mitotic checkpoint prot... 42 0.005
AB011093-1|BAA25447.1| 1050|Homo sapiens KIAA0521 protein protein. 42 0.005
X05276-1|CAA28888.1| 248|Homo sapiens protein ( Human mRNA for ... 42 0.007
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 42 0.007
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 42 0.007
S67247-1|AAB28952.1| 226|Homo sapiens smooth muscle myosin heav... 42 0.007
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 42 0.007
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 42 0.007
BT019634-1|AAV38440.1| 248|Homo sapiens tropomyosin 4 protein. 42 0.007
BC067225-1|AAH67225.1| 248|Homo sapiens tropomyosin 4 protein. 42 0.007
BC037576-1|AAH37576.1| 248|Homo sapiens tropomyosin 4 protein. 42 0.007
BC009964-1|AAH09964.1| 718|Homo sapiens MAD1 mitotic arrest def... 42 0.007
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 42 0.007
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 42 0.007
BC007877-1|AAH07877.2| 256|Homo sapiens MYH14 protein protein. 42 0.007
AL832636-1|CAD89951.1| 546|Homo sapiens hypothetical protein pr... 42 0.007
AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 42 0.007
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 42 0.007
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 42 0.007
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 42 0.007
AF123318-1|AAD20359.1| 718|Homo sapiens mitotic checkpoint prot... 42 0.007
Y17282-1|CAA76730.1| 551|Homo sapiens cytokeratin type II protein. 41 0.009
BC127760-1|AAI27761.1| 658|Homo sapiens Unknown (protein for IM... 41 0.009
BC103824-1|AAI03825.1| 546|Homo sapiens taxilin alpha protein. 41 0.009
BC103823-1|AAI03824.1| 546|Homo sapiens taxilin alpha protein. 41 0.009
BC101517-1|AAI01518.1| 637|Homo sapiens RAB11 family interactin... 41 0.009
BC093914-1|AAH93914.1| 637|Homo sapiens RAB11 family interactin... 41 0.009
BC080578-1|AAH80578.1| 546|Homo sapiens taxilin alpha protein. 41 0.009
BC058933-1|AAH58933.1| 377|Homo sapiens IKK interacting protein... 41 0.009
BC057227-1|AAH57227.1| 318|Homo sapiens Unknown (protein for IM... 41 0.009
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 41 0.009
BC002827-1|AAH02827.1| 248|Homo sapiens tropomyosin 4 protein. 41 0.009
AY169244-1|AAO21970.1| 637|Homo sapiens rab11-family interactin... 41 0.009
AL049795-2|CAI22055.1| 546|Homo sapiens novel protein protein. 41 0.009
AK125971-1|BAC86369.1| 483|Homo sapiens protein ( Homo sapiens ... 41 0.009
AK097424-1|BAC05045.1| 535|Homo sapiens protein ( Homo sapiens ... 41 0.009
AK055613-1|BAB70970.1| 377|Homo sapiens protein ( Homo sapiens ... 41 0.009
AJ539425-1|CAD62380.1| 377|Homo sapiens IKIP1 protein. 41 0.009
AJ314646-1|CAC44535.1| 609|Homo sapiens hypothetical protein pr... 41 0.009
AF516206-1|AAO42465.1| 546|Homo sapiens taxilin protein. 41 0.009
AB058724-1|BAB47450.1| 609|Homo sapiens KIAA1821 protein protein. 41 0.009
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 41 0.009
BX640704-1|CAE45824.1| 594|Homo sapiens hypothetical protein pr... 41 0.012
BX530088-3|CAI95786.1| 841|Homo sapiens GRIP1 associated protei... 41 0.012
BX530088-2|CAI95785.1| 796|Homo sapiens GRIP1 associated protei... 41 0.012
BC101546-1|AAI01547.1| 841|Homo sapiens GRIP1 associated protei... 41 0.012
BC101544-1|AAI01545.1| 841|Homo sapiens GRIP1 associated protei... 41 0.012
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 255 bits (624), Expect = 3e-67
Identities = 139/462 (30%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LESER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 76.6 bits (180), Expect = 2e-13
Identities = 84/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LES
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 58.8 bits (136), Expect = 4e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELESERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 58.0 bits (134), Expect = 7e-08
Identities = 73/397 (18%), Positives = 153/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E+
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELESER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 255 bits (624), Expect = 3e-67
Identities = 139/462 (30%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LESER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 76.6 bits (180), Expect = 2e-13
Identities = 84/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LES
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 58.8 bits (136), Expect = 4e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELESERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 58.0 bits (134), Expect = 7e-08
Identities = 73/397 (18%), Positives = 153/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E+
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELESER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 254 bits (622), Expect = 5e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 72.9 bits (171), Expect = 2e-12
Identities = 82/412 (19%), Positives = 177/412 (42%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E R + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 67.3 bits (157), Expect = 1e-10
Identities = 85/443 (19%), Positives = 168/443 (37%), Gaps = 39/443 (8%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+L ++ ++E + + L +V LE+ +
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH----ELEKVRKQLEAEK 1537
Query: 270 VQLE---EESEARLDLER-QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++L+ EE+EA L+ E ++++A E +++ +
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSL 1597
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE---------- 375
N + K +++ ++ + I L AN A E QK+ + L+
Sbjct: 1598 QTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQL 1657
Query: 376 ----RVNIEIK-------------SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
R N ++K + LEE + EQT+R + EL S +
Sbjct: 1658 DDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHS 1717
Query: 419 QKDALARENKKMGDDLHDARANI 441
Q +L + KKM DL + +
Sbjct: 1718 QNTSLINQKKKMDADLSQLQTEV 1740
Score = 57.6 bits (133), Expect = 1e-07
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 54.8 bits (126), Expect = 7e-07
Identities = 72/397 (18%), Positives = 151/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.4 bits (120), Expect = 4e-06
Identities = 71/420 (16%), Positives = 170/420 (40%), Gaps = 20/420 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTALKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAE 143
+ + + ++ ++ + LED E E A L KK ++ + + ID L T A+ E
Sbjct: 909 IKNKIQLEAKVKEMNERLED---EEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVE 965
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
KEK + +V L ++ + + ++K + L+ + ++ + +T K
Sbjct: 966 KEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKV 1025
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+L Q+ +L ++ K ++ K ++ L + +
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
+L ++ ++E+E L+++L + I +
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEE 1145
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNI 379
A +E K R ++E + + DLE+A TA L+K+ + V
Sbjct: 1146 ISERLEEAGGATSCQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-A 1201
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
E+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1202 ELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 47.6 bits (108), Expect = 1e-04
Identities = 63/397 (15%), Positives = 149/397 (37%), Gaps = 10/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ +E IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVE-RRNNLQAELEEL-RAVVEQTERSRKLADRELIETS 1709
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1710 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1769
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1770 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1827
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1828 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1886
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1887 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1919
Score = 44.4 bits (100), Expect = 0.001
Identities = 39/206 (18%), Positives = 90/206 (43%), Gaps = 6/206 (2%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D + + DL + ++ +Q +LE R + ++ ER + ++I+ SER++
Sbjct: 1658 DDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHS 1717
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
S +K D +L +L+ +E+ E KK + + E++ + T A
Sbjct: 1718 QNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM-MAEELKKEQDTSA 1776
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITI---SKTCERLEITISELHIKIEELNRTIVD 197
E+ K + + +L +++ E+I + K ++LE + EL ++E + +
Sbjct: 1777 HLERMKKNMEQTIKDLQHRLDEA--EQIALKGGKKQLQKLEARVRELENELEAEQKRNAE 1834
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNI 223
++ + EL + ++ + N+
Sbjct: 1835 SVKGMRKSERRIKELTYQTEEDRKNL 1860
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 254 bits (622), Expect = 5e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 57.6 bits (133), Expect = 1e-07
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 54.8 bits (126), Expect = 7e-07
Identities = 72/397 (18%), Positives = 151/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSCQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 254 bits (621), Expect = 7e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 324 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 383
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 384 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 443
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 444 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 503
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 504 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 563
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 564 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 623
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 624 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 683
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 684 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 743
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 744 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 785
Score = 76.2 bits (179), Expect = 3e-13
Identities = 83/412 (20%), Positives = 179/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 103 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 162
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 163 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 221
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 222 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 281
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L+ ++ + + + ++ A + ++E +LE+
Sbjct: 282 IMDLENDKQQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 341
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 342 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 401
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 402 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 461
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 462 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 513
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 396 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 455
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 456 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 514
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 515 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 574
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 575 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 634
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 635 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 693
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 694 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 753
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 754 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 804
Score = 65.7 bits (153), Expect = 4e-10
Identities = 85/440 (19%), Positives = 168/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 522 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 577
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 578 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 637
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 638 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 697
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 698 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 757
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 758 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 817
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 818 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 877
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + EL S + Q
Sbjct: 878 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNT 937
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 938 SLINQKKKMDADLSQLQTEV 957
Score = 58.4 bits (135), Expect = 6e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 242 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDF 301
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 302 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 360
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 361 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 420
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 421 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 480
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 481 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 529
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 530 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 589
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 590 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 642
Score = 57.2 bits (132), Expect = 1e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 224 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 283
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 284 DLENDKQQLEERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 342
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 343 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 401
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 402 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 461
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 462 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 520
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 521 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 580
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 581 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 616
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 65 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 124
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 125 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 182
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 183 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 242
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 243 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFE 302
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 303 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 362
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 363 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 418
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 419 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 477
Score = 50.4 bits (115), Expect = 1e-05
Identities = 63/397 (15%), Positives = 148/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 748 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 807
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 808 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 867
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN-IELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ E IE
Sbjct: 868 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLADEELIETS 926
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 927 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 986
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 987 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1044
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1045 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1103
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1104 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1136
Score = 31.5 bits (68), Expect = 7.3
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 205 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 264
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 265 ERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELNALNARI 310
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 254 bits (621), Expect = 7e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 58.4 bits (135), Expect = 6e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 56.8 bits (131), Expect = 2e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 254 bits (621), Expect = 7e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 58.4 bits (135), Expect = 6e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 56.8 bits (131), Expect = 2e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 254 bits (621), Expect = 7e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1108 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1167
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1168 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 1347
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1348 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1407
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1467
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1468 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1527
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1569
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1180 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1239
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 1240 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 1298
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1299 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1418
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1419 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1477
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1478 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1537
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1588
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 887 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 946
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 947 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1005
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 1065
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 1066 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 1125
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 1185
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 1246 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 1306 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1361
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1362 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1421
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1422 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1481
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1482 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1541
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1542 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1601
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1602 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1661
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1662 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1721
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1722 SLINQKKKMDADLSQLQTEV 1741
Score = 58.4 bits (135), Expect = 6e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 1026 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 1085
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 1086 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1145 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1204
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 1264
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 1265 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 1313
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1314 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1374 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1426
Score = 56.8 bits (131), Expect = 2e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 1008 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1067
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 1068 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 1126
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 1127 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 1185
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 1186 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1245
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 1246 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 1304
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 1305 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1364
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1365 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1400
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 849 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 908
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 909 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 966
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 967 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 1026
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 1027 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 1086
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 1146
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 1147 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 1202
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 1203 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 1261
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1532 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1591
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1592 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1651
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1652 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1710
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1711 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1770
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1771 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1828
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1887
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1888 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1920
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 989 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 1048
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 1049 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 1094
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 254 bits (621), Expect = 7e-67
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 747 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 806
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 807 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 866
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 867 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 926
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 927 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 986
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 987 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 1046
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1047 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1106
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1107 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 1166
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1167 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 1208
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 819 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 878
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 879 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENG-ELSRQLDEKEALI 937
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 938 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 997
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 998 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 1057
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1058 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1116
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 1117 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 1176
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1177 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1227
Score = 75.4 bits (177), Expect = 5e-13
Identities = 83/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 526 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 585
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 586 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 644
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 645 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 704
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 705 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 764
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 765 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 824
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 825 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 884
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL +++ +LQ + EL + ++K+AL
Sbjct: 885 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 936
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 945 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 1000
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 1001 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 1060
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 1061 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 1120
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 1121 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 1180
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 1181 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 1240
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 1241 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 1300
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 1301 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 1360
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 1361 SLINQKKKMDADLSQLQTEV 1380
Score = 58.4 bits (135), Expect = 6e-08
Identities = 85/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 665 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 724
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 725 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 783
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 784 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 843
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 844 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 903
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S R +L+ E+ +L RQL + I S+
Sbjct: 904 ETQRSVN----DLTSQRAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 952
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 953 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1012
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1013 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 1065
Score = 56.8 bits (131), Expect = 2e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 647 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 706
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 707 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 765
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 766 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 824
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 825 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 884
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 885 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRG 943
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 944 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 1003
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 1004 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 1039
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 488 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 547
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 548 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 605
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 606 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 665
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 666 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 725
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 726 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 785
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 786 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 841
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 842 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 900
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 1171 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 1230
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 1231 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 1290
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 1291 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 1349
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 1350 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1409
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1410 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1467
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1468 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1526
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1527 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1559
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 628 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 687
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 688 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 733
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 253 bits (620), Expect = 1e-66
Identities = 138/462 (29%), Positives = 238/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L L+ +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 352 LKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 411
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 412 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 471
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K C LE ++E K EE R++ D+TS + +L EN EL
Sbjct: 472 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGEL 531
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + I + K Q +L D + +R Q
Sbjct: 532 SRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQY 591
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 592 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV 651
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 652 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 711
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 712 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELE 771
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 772 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 813
Score = 77.0 bits (181), Expect = 1e-13
Identities = 84/412 (20%), Positives = 178/412 (43%), Gaps = 25/412 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 131 LQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 190
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L++ ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 191 CSELKRDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 249
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 250 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQES 309
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + + + ++ A + ++E +LE+
Sbjct: 310 IMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAE 369
Query: 269 RVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R DL R+ L +A G E+ R ++F
Sbjct: 370 RTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQH 429
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++L+ ++ K L
Sbjct: 430 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 489
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
E++ ++ ++ E E+TQR DL ++Q +LQ + EL + ++K+AL
Sbjct: 490 EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEAL 541
Score = 75.8 bits (178), Expect = 3e-13
Identities = 64/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 424 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 483
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ ++ R + ++ + R E+ + K E + Q+D+
Sbjct: 484 KAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENG-ELSRQLDEKEALI 542
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 543 SQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 602
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 603 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTK 662
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 663 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 721
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 722 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 781
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 782 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 832
Score = 66.5 bits (155), Expect = 2e-10
Identities = 85/440 (19%), Positives = 169/440 (38%), Gaps = 32/440 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L+ +LED R ++++++++ L ++ + D + Q E E E AE Q +
Sbjct: 550 LTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE---ETEAKAELQ-RVL 605
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K ++E+ + R E ++ E KKK + + + +E ++ + + EK K +
Sbjct: 606 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRL 665
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
Q E+ +L+ VE + K + ++E K EE + + LS E
Sbjct: 666 QNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTEL 725
Query: 210 IEL-------VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+L ++ ++ K +N+ S + Q A +++
Sbjct: 726 FKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQ 785
Query: 263 IDLESVRVQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
LE LE E ++ + ++ER+L + + E+ +
Sbjct: 786 SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSL 845
Query: 312 XXXXXKYSXXXXXXXXXXXTL------IAKINNV----EKQKSRLQSEVEVLIIDLEKAN 361
+ L ++ N + +KQ LQS ++ I L+ A
Sbjct: 846 DAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV 905
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+L++ +ER N +++ LEE + EQT+R + + EL S + Q
Sbjct: 906 RANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNT 965
Query: 422 ALARENKKMGDDLHDARANI 441
+L + KKM DL + +
Sbjct: 966 SLINQKKKMDADLSQLQTEV 985
Score = 56.8 bits (131), Expect = 2e-07
Identities = 73/397 (18%), Positives = 152/397 (38%), Gaps = 8/397 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DDL++E + + + K L QV L LE+ + RK + +L ++ +
Sbjct: 252 DDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 311
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D+ + ++ LKKK+ E+ +I+ ++ +K+ + QA + EL ++E
Sbjct: 312 DLENDKQQLDERLKKKDFELNA-LNARIEDEQALGSQLQKKLKELQARIEELEEELEAER 370
Query: 165 KEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+ + K L + E+ ++EE T V I +K+R E ++ +++++ +
Sbjct: 371 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQH 429
Query: 224 E-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
E L+ + A + +++L+ V +E+ +A+ +L
Sbjct: 430 EATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 489
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E+ ++ RSK K A I+ + +
Sbjct: 490 EKMCRTLEDQMNEHRSK-AEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRG 548
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K ++E L LE+ L + ++ + EE + + QR L
Sbjct: 549 KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKA 608
Query: 403 QTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
+E+ R +E D ++ + L KK+ L +A
Sbjct: 609 NSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQEA 644
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/413 (20%), Positives = 163/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E + E +K+D
Sbjct: 270 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDF 329
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL L +ED + LK+ Q + + +E+++ +A+ EK +S E+
Sbjct: 330 ELNALNARIEDEQALGSQLQKKLKEL-QARIEELEEELEAERTARAKVEKLRSDLSRELE 388
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 389 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 448
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 449 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAE 508
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
S++ DL S + +L+ E+ +L RQL + I S+
Sbjct: 509 ETQRSVN----DLTSQQAKLQTENG---ELSRQLDEKEALI----SQLTRGKLTYTQQLE 557
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 558 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 617
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 618 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIE 670
Score = 52.0 bits (119), Expect = 5e-06
Identities = 70/419 (16%), Positives = 172/419 (41%), Gaps = 18/419 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ +++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 93 MASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQL 152
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + + ID L T A+ EK
Sbjct: 153 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKRDIDDLELTLAKVEK 210
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V L ++ + + ++K + L+ + ++ + +T K +
Sbjct: 211 EKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVK 270
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L Q+ +L ++ K ++ K ++ L + + +
Sbjct: 271 LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFE 330
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L ++ ++E+E L+++L + I +
Sbjct: 331 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEI 390
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA----NGTARELQKRTEQLERVNIE 380
A +E K R ++E + + DLE+A TA L+K+ + V E
Sbjct: 391 SERLEEAGGATSVQIEMNKKR-EAEFQKMRRDLEEATLQHEATAAALRKK--HADSV-AE 446
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ +++ ++ ++ +++ + EL V+ +++ + K L + + + D +++ R+
Sbjct: 447 LGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRS 505
Score = 51.2 bits (117), Expect = 8e-06
Identities = 64/397 (16%), Positives = 149/397 (37%), Gaps = 9/397 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + +Q LE + E + ++ Q+ +E + + E ++
Sbjct: 776 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHL 835
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + D S A +KKK + + + + Q+ + A A+K+ Q+ +
Sbjct: 836 RVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLK 895
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS-QENIELV 213
+ Q+++ + + + +E + L ++EEL R +V+ T ++L+ QE IE
Sbjct: 896 DTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTERSRKLAEQELIETS 954
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ VQ L +++ K ++ + + D + +L+
Sbjct: 955 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1014
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+E + LER I + + K
Sbjct: 1015 KEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA-- 1072
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ N E K +SE + + + + L + + ++++ +++K+ + + E
Sbjct: 1073 EQKRNAESVKGMRKSERRIKELTYQ-TEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEE 1131
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
Q +L ++ ++V HELD+ E+ D + K+
Sbjct: 1132 QANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1164
Score = 31.1 bits (67), Expect = 9.7
Identities = 23/106 (21%), Positives = 43/106 (40%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
I + K+K LQ + + DL+ L K +LE+ +++ LE+ ++
Sbjct: 233 IAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDL 292
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+R R + +L+ + K L KK +L+ A I
Sbjct: 293 ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARI 338
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 249 bits (609), Expect = 2e-65
Identities = 139/462 (30%), Positives = 234/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1112 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR 1171
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+ + E
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1231
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E V+K K + K C LE +SE+ K EE R I D+T+ + RL E+ E
Sbjct: 1232 IDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEY 1291
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + K Q +L D + +R Q
Sbjct: 1292 SRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY 1351
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE EA+ +L+R + KAN E+ WR+K+ K + +
Sbjct: 1352 EEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L+ID+E+ N L K+ +++ E K + EET
Sbjct: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 1472 EASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELK 1531
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1532 KIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVK 1573
Score = 74.1 bits (174), Expect = 1e-12
Identities = 64/404 (15%), Positives = 165/404 (40%), Gaps = 6/404 (1%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + D + + + +++ + ++Q++E+EK+++ +++ L+ +E
Sbjct: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + +L +++ K E L ++ TA + + + ++ Q+D+
Sbjct: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG--EYSRQLDEKDTL 1301
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K F ++ EL Q+E K K ++ + L + EE ++
Sbjct: 1302 VSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAEL 1361
Query: 199 TSHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
+ + E + K D E + K ++A + +
Sbjct: 1362 QRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKT 1421
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+++ ++E + + +E + A L+++ + + W+ K
Sbjct: 1422 KQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRS- 1480
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S + ++ ++++ LQ E+ L + + EL+K +Q+E+
Sbjct: 1481 LSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQE 1540
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1541 KSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1584
Score = 72.1 bits (169), Expect = 4e-12
Identities = 93/488 (19%), Positives = 183/488 (37%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ D L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 891 LQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 950
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ KEK Q +
Sbjct: 951 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1010 TLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQES 1069
Query: 210 -IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
+++ + Q L ++ + S + S+ A + ++E ++E+
Sbjct: 1070 TMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE 1129
Query: 269 RVQLEEESEARLDLERQL---------------------VKANGEIGHWRSKFXXXXXXX 307
R + + R DL R+L K E R
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1189
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K++ L +EK+KS ++ E++ L ++E + L
Sbjct: 1190 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 1249
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+K LE EIK++ EE +L QTE S +LD+ L+R
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGK 1309
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + + Y+E E KAE QR+ +
Sbjct: 1310 QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE-EQEAKAELQRAMSKA 1368
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 1369 NSEVAQWR 1376
Score = 70.1 bits (164), Expect = 2e-11
Identities = 85/421 (20%), Positives = 173/421 (41%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE
Sbjct: 1411 VNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1470
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQI-------DQ 134
E+ + +R TEL K++ E+ L+ ET K Q+ + D EQI +
Sbjct: 1471 LEASQKESRSLSTELFKIKNAYEE-SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1529
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVEN----VTKEKITISKTCERLEITISELHIKIEE 190
L K K + E+EKS+ QA + E A +E+ + + ++ +++ ++ I+E +I++
Sbjct: 1530 LKKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXX 250
+ R + I Q I + LK +E + +++ Q
Sbjct: 1590 MKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDL---NEMEIQLNHANRMAAEALRN 1646
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
A L ++ L+ E+ E +ER+ EI R+
Sbjct: 1647 YRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1706
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
S +LI +E S++Q E+E +I + EKA +
Sbjct: 1707 EQELLDA-SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITD 1765
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 1766 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVR 1824
Query: 426 E 426
E
Sbjct: 1825 E 1825
Score = 58.8 bits (136), Expect = 4e-08
Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + E + E +K++
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ L+ +ED + +K+ Q + + +E+I+ ++A+AEK++S E+
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKEL-QARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Query: 155 EL-----------LAQVENVTKEKITISKTCERLE----------ITISELHI-KIEELN 192
E+ AQ+E K + K LE T+ + H + EL
Sbjct: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1208
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E+ E+ DL N+E V K +
Sbjct: 1209 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 1249
Score = 54.4 bits (125), Expect = 9e-07
Identities = 81/429 (18%), Positives = 169/429 (39%), Gaps = 34/429 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
++E+ R ++++++++ L ++ + D + Q E E E AE Q ++ K ++
Sbjct: 1315 QIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE---EQEAKAELQRAMS-KANS 1370
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ + R E ++ E KKK + + D +E ++ + A EK K + Q EV
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 1430
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL-- 212
+L+ VE + K + ++E K EE + + + LS E ++
Sbjct: 1431 DLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKN 1490
Query: 213 -----VKEVQDLKVNIENVVY----LKSQIAS---QXXXXXXXXXXXXXXXXXXXASLHQ 260
+ +++ LK +N+ L QIA + A+L +
Sbjct: 1491 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEE 1550
Query: 261 VEIDLES-----VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
E LE +R+QLE ++ + +++R++ + + EI +
Sbjct: 1551 AEASLEHEEGKILRIQLEL-NQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEI 1609
Query: 316 XKYSXXXXXXXXXXXTL------IAKINNVEKQKSRLQSEVEVLIID----LEKANGTAR 365
+ L + N + + R + ++ D L+ A +
Sbjct: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+++ +ER +++ +EE EQT+R + + EL S + Q +L
Sbjct: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
Query: 426 ENKKMGDDL 434
KK+ D+
Sbjct: 1730 TKKKLETDI 1738
Score = 51.2 bits (117), Expect = 8e-06
Identities = 37/192 (19%), Positives = 89/192 (46%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ SER++ S +K
Sbjct: 1675 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1734
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T++ +++ +ED+ E+ KK + + E++ + T A E+ K +
Sbjct: 1735 ETDISQIQGEMEDIIQEARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1793
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + V+ ++ ++ E
Sbjct: 1794 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKE 1853
Query: 212 LVKEVQDLKVNI 223
L + ++ + NI
Sbjct: 1854 LTYQTEEDRKNI 1865
Score = 50.8 bits (116), Expect = 1e-05
Identities = 67/353 (18%), Positives = 141/353 (39%), Gaps = 18/353 (5%)
Query: 98 KLRKLLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
K++ LL+ E +E A++ ++ K +E + + + +L + +EK+ Q +V
Sbjct: 839 KIKPLLKSAETE-KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ + + + KT +LE I E+ + E+ ++T+ K++L E EL K+
Sbjct: 898 EADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 216 VQDLKVNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESV 268
+ DL++ + V K + ++ HQ +D L++
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 269 RVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
++ ++A++ LE+Q+ G + K
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSLEQ-EKKIRMDLERAKRKLEGDLKLAQESTMDIEND 1076
Query: 329 XXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEET 388
L K+ E + S LQS++E E+A G +LQK+ ++L+ E++ +E
Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSKIED-----EQALGM--QLQKKIKELQARIEELEEEIEAE 1129
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ ++ + EL+ +S L++ A NKK + R ++
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1182
Score = 50.8 bits (116), Expect = 1e-05
Identities = 68/389 (17%), Positives = 161/389 (41%), Gaps = 19/389 (4%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-VHLESEETAHLL 117
+EK DL +QV ++ L +AE + + + + ++ ++ + ED + +E TA
Sbjct: 886 QEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK-- 943
Query: 118 KKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV--TKEKITISKTC- 174
K+K ++ + ++ ID L T A+ EKEK + +V L ++ + T K+T K
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 175 -ERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
E + T+ +L + +++N +T K +L Q+ +L ++ K ++ K ++
Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
L + E ++ ++ ++E+E + L++++ + I
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
+ A +E K R ++E + +
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR-EAEFQKM 1178
Query: 354 IIDLEKA----NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
DLE+A TA L+K+ + V E+ +++ ++ ++ +++ + E+ +
Sbjct: 1179 RRDLEEATLQHEATAATLRKK--HADSV-AELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Query: 410 SHELDKTREQKDALARENKKMGDDLHDAR 438
+ ++ + K L + + + D L + +
Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 249 bits (609), Expect = 2e-65
Identities = 139/462 (30%), Positives = 234/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1112 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR 1171
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+ + E
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1231
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E V+K K + K C LE +SE+ K EE R I D+T+ + RL E+ E
Sbjct: 1232 IDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEY 1291
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + K Q +L D + +R Q
Sbjct: 1292 SRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY 1351
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE EA+ +L+R + KAN E+ WR+K+ K + +
Sbjct: 1352 EEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L+ID+E+ N L K+ +++ E K + EET
Sbjct: 1412 NAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1471
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 1472 EASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELE 1531
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1532 KIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVK 1573
Score = 74.5 bits (175), Expect = 8e-13
Identities = 64/404 (15%), Positives = 165/404 (40%), Gaps = 6/404 (1%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + D + + + +++ + ++Q++E+EK+++ +++ L+ +E
Sbjct: 1184 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 1243
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + +L +++ K E L ++ TA + + + ++ Q+D+
Sbjct: 1244 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESG--EYSRQLDEKDTL 1301
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K F ++ EL Q+E K K ++ + L + EE ++
Sbjct: 1302 VSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAEL 1361
Query: 199 TSHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
+ + E + K D E + K ++A + +
Sbjct: 1362 QRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKT 1421
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+++ ++E + + +E + A L+++ + + W+ K
Sbjct: 1422 KQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRS- 1480
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S + ++ ++++ LQ E+ L + + EL+K +Q+E+
Sbjct: 1481 LSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1540
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1541 KSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1584
Score = 72.1 bits (169), Expect = 4e-12
Identities = 93/488 (19%), Positives = 183/488 (37%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ D L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 891 LQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 950
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ KEK Q +
Sbjct: 951 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1010 TLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQES 1069
Query: 210 -IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
+++ + Q L ++ + S + S+ A + ++E ++E+
Sbjct: 1070 AMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE 1129
Query: 269 RVQLEEESEARLDLERQL---------------------VKANGEIGHWRSKFXXXXXXX 307
R + + R DL R+L K E R
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1189
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K++ L +EK+KS ++ E++ L ++E + L
Sbjct: 1190 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 1249
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+K LE EIK++ EE +L QTE S +LD+ L+R
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGK 1309
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + + Y+E E KAE QR+ +
Sbjct: 1310 QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE-EQEAKAELQRAMSKA 1368
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 1369 NSEVAQWR 1376
Score = 70.1 bits (164), Expect = 2e-11
Identities = 85/421 (20%), Positives = 173/421 (41%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE
Sbjct: 1411 VNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 1470
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQI-------DQ 134
E+ + +R TEL K++ E+ L+ ET K Q+ + D EQI +
Sbjct: 1471 LEASQKESRSLSTELFKIKNAYEE-SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1529
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVEN----VTKEKITISKTCERLEITISELHIKIEE 190
L K K + E+EKS+ QA + E A +E+ + + ++ +++ ++ I+E +I++
Sbjct: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXX 250
+ R + I Q I + LK +E + +++ Q
Sbjct: 1590 MKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDL---NEMEIQLNHANRMAAEALRN 1646
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
A L ++ L+ E+ E +ER+ EI R+
Sbjct: 1647 YRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 1706
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
S +LI +E S++Q E+E +I + EKA +
Sbjct: 1707 EQELLDA-SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITD 1765
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 1766 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVR 1824
Query: 426 E 426
E
Sbjct: 1825 E 1825
Score = 58.8 bits (136), Expect = 4e-08
Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + E + E +K++
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEF 1089
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ L+ +ED + +K+ Q + + +E+I+ ++A+AEK++S E+
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKEL-QARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Query: 155 EL-----------LAQVENVTKEKITISKTCERLE----------ITISELHI-KIEELN 192
E+ AQ+E K + K LE T+ + H + EL
Sbjct: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1208
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E+ E+ DL N+E V K +
Sbjct: 1209 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNL 1249
Score = 54.4 bits (125), Expect = 9e-07
Identities = 81/429 (18%), Positives = 169/429 (39%), Gaps = 34/429 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
++E+ R ++++++++ L ++ + D + Q E E E AE Q ++ K ++
Sbjct: 1315 QIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE---EQEAKAELQRAMS-KANS 1370
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ + R E ++ E KKK + + D +E ++ + A EK K + Q EV
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 1430
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL-- 212
+L+ VE + K + ++E K EE + + + LS E ++
Sbjct: 1431 DLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKN 1490
Query: 213 -----VKEVQDLKVNIENVVY----LKSQIAS---QXXXXXXXXXXXXXXXXXXXASLHQ 260
+ +++ LK +N+ L QIA + A+L +
Sbjct: 1491 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEE 1550
Query: 261 VEIDLES-----VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
E LE +R+QLE ++ + +++R++ + + EI +
Sbjct: 1551 AEASLEHEEGKILRIQLEL-NQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEI 1609
Query: 316 XKYSXXXXXXXXXXXTL------IAKINNVEKQKSRLQSEVEVLIID----LEKANGTAR 365
+ L + N + + R + ++ D L+ A +
Sbjct: 1610 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQE 1669
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+++ +ER +++ +EE EQT+R + + EL S + Q +L
Sbjct: 1670 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 1729
Query: 426 ENKKMGDDL 434
KK+ D+
Sbjct: 1730 TKKKLETDI 1738
Score = 51.2 bits (117), Expect = 8e-06
Identities = 37/192 (19%), Positives = 89/192 (46%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ SER++ S +K
Sbjct: 1675 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1734
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T++ +++ +ED+ E+ KK + + E++ + T A E+ K +
Sbjct: 1735 ETDISQIQGEMEDIIQEARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1793
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + V+ ++ ++ E
Sbjct: 1794 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKE 1853
Query: 212 LVKEVQDLKVNI 223
L + ++ + NI
Sbjct: 1854 LTYQTEEDRKNI 1865
Score = 50.8 bits (116), Expect = 1e-05
Identities = 67/353 (18%), Positives = 141/353 (39%), Gaps = 18/353 (5%)
Query: 98 KLRKLLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
K++ LL+ E +E A++ ++ K +E + + + +L + +EK+ Q +V
Sbjct: 839 KIKPLLKSAETE-KEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQA 897
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ + + + KT +LE I E+ + E+ ++T+ K++L E EL K+
Sbjct: 898 EADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 216 VQDLKVNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESV 268
+ DL++ + V K + ++ HQ +D L++
Sbjct: 958 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 269 RVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
++ ++A++ LE+Q+ G + K
Sbjct: 1018 EDKVNTLTKAKIKLEQQVDDLEGSLEQ-EKKIRMDLERAKRKLEGDLKLAQESAMDIEND 1076
Query: 329 XXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEET 388
L K+ E + S LQS++E E+A G +LQK+ ++L+ E++ +E
Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSKIED-----EQALGM--QLQKKIKELQARIEELEEEIEAE 1129
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ ++ + EL+ +S L++ A NKK + R ++
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDL 1182
Score = 50.8 bits (116), Expect = 1e-05
Identities = 68/389 (17%), Positives = 161/389 (41%), Gaps = 19/389 (4%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-VHLESEETAHLL 117
+EK DL +QV ++ L +AE + + + + ++ ++ + ED + +E TA
Sbjct: 886 QEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK-- 943
Query: 118 KKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV--TKEKITISKTC- 174
K+K ++ + ++ ID L T A+ EKEK + +V L ++ + T K+T K
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 175 -ERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
E + T+ +L + +++N +T K +L Q+ +L ++ K ++ K ++
Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
L + E ++ ++ ++E+E + L++++ + I
Sbjct: 1060 EGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
+ A +E K R ++E + +
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR-EAEFQKM 1178
Query: 354 IIDLEKA----NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
DLE+A TA L+K+ + V E+ +++ ++ ++ +++ + E+ +
Sbjct: 1179 RRDLEEATLQHEATAATLRKK--HADSV-AELGEQIDNLQRVKQKLEKEKSEMKMEIDDL 1235
Query: 410 SHELDKTREQKDALARENKKMGDDLHDAR 438
+ ++ + K L + + + D L + +
Sbjct: 1236 ASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 248 bits (608), Expect = 3e-65
Identities = 135/462 (29%), Positives = 237/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L + +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1169
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1170 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K LE +E +K+EE R++ D T+ + +L EN EL
Sbjct: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + I + K Q +L D + +R Q
Sbjct: 1290 ARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQY 1349
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1350 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAV 1409
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1410 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1469
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1470 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIK 1571
Score = 75.4 bits (177), Expect = 5e-13
Identities = 89/414 (21%), Positives = 183/414 (44%), Gaps = 29/414 (7%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 889 LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 948
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 949 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 156 LLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L ++ V ++K+ ++SK+ +LE + +L +E+ + +D+ K++L + +++L +
Sbjct: 1008 ALDDLQ-VEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL-EGDLKLTQ 1065
Query: 215 E-VQDL---KVNIENVVYLK----SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + DL K+ +E + K +Q S+ A + ++E +LE
Sbjct: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELE 1125
Query: 267 SVRVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXX 312
+ R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE 372
+ L +I+N+++ K +L+ E ++L+ ++ K
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245
Query: 373 QLERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
LE+V+ ++ + E E+ QR D ++ +LQ + EL + E+K+AL
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEAL 1299
Score = 73.7 bits (173), Expect = 1e-12
Identities = 63/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1182 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1241
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +++R + + + R LE+ + K E + Q+++
Sbjct: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENG-ELARQLEEKEALI 1300
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1361 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1479
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + EL+K +QLE
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEK 1539
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1540 LELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Score = 65.3 bits (152), Expect = 5e-10
Identities = 74/415 (17%), Positives = 157/415 (37%), Gaps = 10/415 (2%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINR 90
AL L+++ E E E + ++R + + +V Q + E +A E E +
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1393
Query: 91 KRDTELLKLRKLLEDVHLES---EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
K L + +E V+ + E+T H L+ + +++++D +++ A +K++
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQR 1449
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
F + E + E E + K L + +L EE + + L +
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +L +++ + N+ + ++ Q+ + + + +++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 268 VRVQLEEESEARLDLERQLVKANGE-IGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ ++E + A D E + K N + + K
Sbjct: 1570 IKAEIERKL-AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KQ LQS ++ I L+ A +L++ +ER N +++ LE
Sbjct: 1629 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1688
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + EQT+R + + EL S + Q +L + KKM DL ++ +
Sbjct: 1689 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
Score = 63.7 bits (148), Expect = 1e-09
Identities = 86/419 (20%), Positives = 177/419 (42%), Gaps = 42/419 (10%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ I++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + ++ ID L T A+ EK
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKKDIDDLELTLAKVEK 968
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQ 203
EK + +V L ++ + ++I T E+ + E H + +++L + S
Sbjct: 969 EKHATENKVKNLTEEMAGL--DEIIAKLTKEKK--ALQEAHQQALDDLQVEEDKVNS--- 1021
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
LS+ ++L ++V DL+ ++E ++ + + ++E
Sbjct: 1022 -LSKSKVKLEQQVDDLEGSLEQEKKVRMDL---------------------ERAKRKLEG 1059
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
DL+ + + + +L LE +L K +I SK +
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEE 1119
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A+ VEK +S L E+E + LE+A G + ++ E +++
Sbjct: 1120 LEEELEAERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 384 RLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
LEE +E T LR K + + + ++D + K L +E + +L D +N+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Score = 52.0 bits (119), Expect = 5e-06
Identities = 49/221 (22%), Positives = 101/221 (45%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E E +K++
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + +ED + + L K+NQ + + +E+++ +A+ EK +S E+
Sbjct: 1088 DINQQNSKIEDEQALALQLQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1147 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1206
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1207 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1247
Score = 51.2 bits (117), Expect = 8e-06
Identities = 65/411 (15%), Positives = 157/411 (38%), Gaps = 13/411 (3%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESE-RELRQRIEREKADL---SVQVIQLSERLEEAEG 80
E ++ L ++ ++ + + +L+S E +E E+ + ++ Q+ +E
Sbjct: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1579
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + E ++ ++ + D S +KKK + + + + Q+ + A
Sbjct: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
A+K+ Q+ + + Q+++ + + + +E + L ++EEL R +V+ T
Sbjct: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTE 1698
Query: 201 HKQRLS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
++L+ QE IE + VQ L +++ K ++ S
Sbjct: 1699 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAK 1758
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ D + +L++E + LER I + + K
Sbjct: 1759 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE 1818
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
+ N E K +SE + + + + L + + ++++ +
Sbjct: 1819 ARVRELEGELEA--EQKRNAESVKGMRKSERRIKELTYQ-TEEDKKNLLRLQDLVDKLQL 1875
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++K+ + + EQ +L ++ ++V HELD+ E+ D + K+
Sbjct: 1876 KVKAYKRQAEEAEEQANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1922
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 248 bits (608), Expect = 3e-65
Identities = 135/462 (29%), Positives = 237/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L + +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1169
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1170 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K LE +E +K+EE R++ D T+ + +L EN EL
Sbjct: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + I + K Q +L D + +R Q
Sbjct: 1290 ARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQY 1349
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1350 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAV 1409
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1410 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1469
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1470 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIK 1571
Score = 74.9 bits (176), Expect = 6e-13
Identities = 89/414 (21%), Positives = 183/414 (44%), Gaps = 29/414 (7%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 889 LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 948
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 949 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 156 LLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L ++ V ++K+ ++SK+ +LE + +L +E+ + +D+ K++L + +++L +
Sbjct: 1008 ALDDLQ-VEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL-EGDLKLTQ 1065
Query: 215 E-VQDL---KVNIENVVYLK----SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + DL K+ +E + K +Q S+ A + ++E +LE
Sbjct: 1066 ESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
Query: 267 SVRVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXX 312
+ R + + R DL R+ L +A G E+ R ++F
Sbjct: 1126 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE 372
+ L +I+N+++ K +L+ E ++L+ ++ K
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1245
Query: 373 QLERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
LE+V+ ++ + E E+ QR D ++ +LQ + EL + E+K+AL
Sbjct: 1246 NLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEAL 1299
Score = 73.7 bits (173), Expect = 1e-12
Identities = 63/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1182 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1241
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +++R + + + R LE+ + K E + Q+++
Sbjct: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENG-ELARQLEEKEALI 1300
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1361 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1479
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + EL+K +QLE
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEK 1539
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1540 LELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Score = 65.3 bits (152), Expect = 5e-10
Identities = 65/326 (19%), Positives = 126/326 (38%), Gaps = 5/326 (1%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVENVTKEK 167
E+ LL++KN ++ + Q + D L + R + K K + +A+V E+ ++E+ +
Sbjct: 877 EKMVSLLQEKN-DLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMN 935
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
++ +LE SEL I++L T+ + K + L +E+ L I +
Sbjct: 936 AELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLT 995
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
K + S ++E ++ + LE+E + R+DLER
Sbjct: 996 KEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKR 1055
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
K G++ + K + + ++K+ Q
Sbjct: 1056 KLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLAL-QLQKKLKENQ 1114
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
+ +E L +LE +++K L R EI RLEE + ++ E Q
Sbjct: 1115 ARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQ 1174
Query: 408 RVSHELDKTREQKDALARENKKMGDD 433
++ +L++ Q +A A +K D
Sbjct: 1175 KMRRDLEEATLQHEATAAALRKKHAD 1200
Score = 65.3 bits (152), Expect = 5e-10
Identities = 74/415 (17%), Positives = 157/415 (37%), Gaps = 10/415 (2%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINR 90
AL L+++ E E E + ++R + + +V Q + E +A E E +
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 1393
Query: 91 KRDTELLKLRKLLEDVHLES---EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
K L + +E V+ + E+T H L+ + +++++D +++ A +K++
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQR 1449
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
F + E + E E + K L + +L EE + + L +
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +L +++ + N+ + ++ Q+ + + + +++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 268 VRVQLEEESEARLDLERQLVKANGE-IGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ ++E + A D E + K N + + K
Sbjct: 1570 IKAEIERKL-AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KQ LQS ++ I L+ A +L++ +ER N +++ LE
Sbjct: 1629 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1688
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + EQT+R + + EL S + Q +L + KKM DL ++ +
Sbjct: 1689 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEV 1743
Score = 63.3 bits (147), Expect = 2e-09
Identities = 86/419 (20%), Positives = 177/419 (42%), Gaps = 42/419 (10%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ I++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + ++ ID L T A+ EK
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKKDIDDLELTLAKVEK 968
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQ 203
EK + +V L ++ + ++I T E+ + E H + +++L + S
Sbjct: 969 EKHATENKVKNLTEEMAGL--DEIIAKLTKEKK--ALQEAHQQALDDLQVEEDKVNS--- 1021
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
LS+ ++L ++V DL+ ++E ++ + + ++E
Sbjct: 1022 -LSKSKVKLEQQVDDLEGSLEQEKKVRMDL---------------------ERAKRKLEG 1059
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
DL+ + + + +L LE +L K +I SK +
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEE 1119
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A+ VEK +S L E+E + LE+A G + ++ E +++
Sbjct: 1120 LEEELEAERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 384 RLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
LEE +E T LR K + + + ++D + K L +E + +L D +N+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Score = 52.8 bits (121), Expect = 3e-06
Identities = 49/221 (22%), Positives = 102/221 (46%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E E +K++
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + +ED + + + L K+NQ + + +E+++ +A+ EK +S E+
Sbjct: 1088 DINQQNSKIEDEQVLALQLQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1147 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1206
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1207 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL 1247
Score = 51.2 bits (117), Expect = 8e-06
Identities = 65/411 (15%), Positives = 157/411 (38%), Gaps = 13/411 (3%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESE-RELRQRIEREKADL---SVQVIQLSERLEEAEG 80
E ++ L ++ ++ + + +L+S E +E E+ + ++ Q+ +E
Sbjct: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1579
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + E ++ ++ + D S +KKK + + + + Q+ + A
Sbjct: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
A+K+ Q+ + + Q+++ + + + +E + L ++EEL R +V+ T
Sbjct: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTE 1698
Query: 201 HKQRLS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
++L+ QE IE + VQ L +++ K ++ S
Sbjct: 1699 RSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAK 1758
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ D + +L++E + LER I + + K
Sbjct: 1759 KAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE 1818
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
+ N E K +SE + + + + L + + ++++ +
Sbjct: 1819 ARVRELEGELEA--EQKRNAESVKGMRKSERRIKELTYQ-TEEDKKNLLRLQDLVDKLQL 1875
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++K+ + + EQ +L ++ ++V HELD+ E+ D + K+
Sbjct: 1876 KVKAYKRQAEEAEEQANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1922
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 248 bits (607), Expect = 4e-65
Identities = 140/462 (30%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1114 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR 1173
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+ + E
Sbjct: 1174 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + VE V+K K + K C LE +SEL K EE R I D+T+ + RL E+ E
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + + K Q +L D + +R Q
Sbjct: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY 1353
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E++ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAV 1413
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L++D+E+ N L K+ +++ E K + EET
Sbjct: 1414 NAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1473
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 1474 EASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELE 1533
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1534 KIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575
Score = 74.9 bits (176), Expect = 6e-13
Identities = 70/407 (17%), Positives = 171/407 (42%), Gaps = 12/407 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + D + + + +++ + ++Q++E+EK+++ +++ L+ +E
Sbjct: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + +L +L+ K E L ++ TA + + Q +F Q+D+
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ--RGRLQTESGEFSRQLDEKEAL 1303
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K F ++ EL Q+E K K ++ + L + EE + ++
Sbjct: 1304 VSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAEL 1363
Query: 199 TSHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ LS+ N E+ K D E + K ++A +
Sbjct: 1364 ---QRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASL 1420
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ +++ ++E + + +E + A L+++ + + W+ K
Sbjct: 1421 EKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA 1480
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ +L ++ ++++ LQ E+ L + + EL+K +Q+
Sbjct: 1481 RSLGTELFKIKNAYEESL-DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV 1539
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+ E+++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1540 EQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1586
Score = 72.1 bits (169), Expect = 4e-12
Identities = 94/488 (19%), Positives = 182/488 (37%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ + L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ KEK Q +
Sbjct: 953 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1012 TLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES 1071
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I ++ E Q L ++ + S + S+ A + ++E ++E+
Sbjct: 1072 IMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAE 1131
Query: 269 RVQLEEESEARLDLERQL---------------------VKANGEIGHWRSKFXXXXXXX 307
R + + R DL R+L K E R
Sbjct: 1132 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1191
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K++ L +EK+KS ++ E++ L ++E + L
Sbjct: 1192 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+K LE E+KS+ EE +L QTE S +LD+ L+R
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + + Y+E E KAE QR+ +
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE-EQESKAELQRALSKA 1370
Query: 487 TAEFGQFR 494
E Q+R
Sbjct: 1371 NTEVAQWR 1378
Score = 68.5 bits (160), Expect = 5e-11
Identities = 86/421 (20%), Positives = 181/421 (42%), Gaps = 46/421 (10%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ + I+D+L R+ +E +EK DL +QV +E L +AE +
Sbjct: 855 MATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL 914
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + ED + +E TA K+K ++ + ++ ID L T A+ EK
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAK--KRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V+N+T+E + +T +L E E +T+ D+ + + +
Sbjct: 973 EKHATE-------NKVKNLTEEMAGLDETIAKL---TKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 205 ---LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
L++ I+L ++V DL+ ++E L+ + + ++
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDL---------------------ERAKRKL 1061
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E DL+ + + + + L+ +L K EI + +SK +
Sbjct: 1062 EGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARI 1121
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
++ EKQ+S L E+E + LE+A G + ++ E ++
Sbjct: 1122 EELEEEIEAERASRA-KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 382 KSRLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
+ LEE +E T LR K + + + ++D + K L +E +M ++ D +N
Sbjct: 1181 RRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN 1240
Query: 441 I 441
+
Sbjct: 1241 V 1241
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E++LR +ER K L + E + + E + E +K++
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ L+ +ED + +K+ Q + + +E+I+ ++A+AEK++S E+
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL-QARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 155 EL-----------LAQVENVTKEKITISKTCERLE----------ITISELHI-KIEELN 192
E+ AQ+E K + K LE T+ + H + EL
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E+ E+ DL N+E V K +
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Score = 51.2 bits (117), Expect = 8e-06
Identities = 52/294 (17%), Positives = 121/294 (41%), Gaps = 11/294 (3%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSA-------LSRLEDKIRLIQDDLESERELRQR 56
MA + YR++ G D I L + L+ +E + L+Q ++E R ++
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL 116
ER + +++ SER++ S +K +T++ +++ +ED+ E+
Sbjct: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
Query: 117 LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKIT-ISKTCE 175
KK + + E++ + T A E+ K + V +L +++ + + K +
Sbjct: 1761 AKKAITDAAM-MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1819
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+LE + EL ++E + + ++ + EL + ++ + NI + L ++ +
Sbjct: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV--RVQLEEESEARLDLERQLV 287
+ A +++ +LE R + E +L ++ + V
Sbjct: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREV 1933
Score = 48.8 bits (111), Expect = 5e-05
Identities = 64/395 (16%), Positives = 142/395 (35%), Gaps = 4/395 (1%)
Query: 42 LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
L+++ E E+E + ++R + + +V Q + E + E +K+ + L+ +
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407
Query: 102 LLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
E V + + A L K K Q V D +++ A +K++ F + E +
Sbjct: 1408 --EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
E E K L + ++ EE + + + L QE +L +++ +
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 220 KVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR 279
I + +K Q+ + + +++++L V+ +++ + +
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 280 LDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNV 339
+ QL + + I K
Sbjct: 1586 DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEA 1645
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
+ Q ++ I L+ A + +L+++ +ER +++ +EE EQT+R
Sbjct: 1646 LRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSR 1705
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + EL S + Q +L KK+ D+
Sbjct: 1706 KIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 248 bits (607), Expect = 4e-65
Identities = 140/462 (30%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1114 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR 1173
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+ + E
Sbjct: 1174 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + VE V+K K + K C LE +SEL K EE R I D+T+ + RL E+ E
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + + K Q +L D + +R Q
Sbjct: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY 1353
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E++ +L+R L KAN E+ WR+K+ K + +
Sbjct: 1354 EEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAV 1413
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L++D+E+ N L K+ +++ E K + EET
Sbjct: 1414 NAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAEL 1473
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 1474 EASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELE 1533
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1534 KIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVK 1575
Score = 74.9 bits (176), Expect = 6e-13
Identities = 70/407 (17%), Positives = 171/407 (42%), Gaps = 12/407 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + D + + + +++ + ++Q++E+EK+++ +++ L+ +E
Sbjct: 1186 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVS 1245
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + +L +L+ K E L ++ TA + + Q +F Q+D+
Sbjct: 1246 KAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQ--RGRLQTESGEFSRQLDEKEAL 1303
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K F ++ EL Q+E K K ++ + L + EE + ++
Sbjct: 1304 VSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAEL 1363
Query: 199 TSHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ LS+ N E+ K D E + K ++A +
Sbjct: 1364 ---QRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASL 1420
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ +++ ++E + + +E + A L+++ + + W+ K
Sbjct: 1421 EKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEA 1480
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ +L ++ ++++ LQ E+ L + + EL+K +Q+
Sbjct: 1481 RSLGTELFKIKNAYEESL-DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV 1539
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+ E+++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1540 EQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1586
Score = 72.1 bits (169), Expect = 4e-12
Identities = 94/488 (19%), Positives = 182/488 (37%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ + L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 893 LQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 952
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ KEK Q +
Sbjct: 953 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1011
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1012 TLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQES 1071
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I ++ E Q L ++ + S + S+ A + ++E ++E+
Sbjct: 1072 IMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAE 1131
Query: 269 RVQLEEESEARLDLERQL---------------------VKANGEIGHWRSKFXXXXXXX 307
R + + R DL R+L K E R
Sbjct: 1132 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1191
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K++ L +EK+KS ++ E++ L ++E + L
Sbjct: 1192 EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+K LE E+KS+ EE +L QTE S +LD+ L+R
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + + Y+E E KAE QR+ +
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEE-EQESKAELQRALSKA 1370
Query: 487 TAEFGQFR 494
E Q+R
Sbjct: 1371 NTEVAQWR 1378
Score = 68.5 bits (160), Expect = 5e-11
Identities = 86/421 (20%), Positives = 181/421 (42%), Gaps = 46/421 (10%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ + I+D+L R+ +E +EK DL +QV +E L +AE +
Sbjct: 855 MATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQL 914
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + ED + +E TA K+K ++ + ++ ID L T A+ EK
Sbjct: 915 IKTKIQLEAKIKEVTERAEDEEEINAELTAK--KRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
EK + +V+N+T+E + +T +L E E +T+ D+ + + +
Sbjct: 973 EKHATE-------NKVKNLTEEMAGLDETIAKL---TKEKKALQEAHQQTLDDLQAEEDK 1022
Query: 205 ---LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
L++ I+L ++V DL+ ++E L+ + + ++
Sbjct: 1023 VNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDL---------------------ERAKRKL 1061
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E DL+ + + + + L+ +L K EI + +SK +
Sbjct: 1062 EGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARI 1121
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
++ EKQ+S L E+E + LE+A G + ++ E ++
Sbjct: 1122 EELEEEIEAERASRA-KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKM 1180
Query: 382 KSRLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
+ LEE +E T LR K + + + ++D + K L +E +M ++ D +N
Sbjct: 1181 RRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN 1240
Query: 441 I 441
+
Sbjct: 1241 V 1241
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/221 (24%), Positives = 100/221 (45%), Gaps = 23/221 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E++LR +ER K L + E + + E + E +K++
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ L+ +ED + +K+ Q + + +E+I+ ++A+AEK++S E+
Sbjct: 1092 EISNLQSKIEDEQALGIQLQKKIKEL-QARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 155 EL-----------LAQVENVTKEKITISKTCERLE----------ITISELHI-KIEELN 192
E+ AQ+E K + K LE T+ + H + EL
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELG 1210
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
I ++ KQ+L +E E+ E+ DL N+E V K +
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL 1251
Score = 51.2 bits (117), Expect = 8e-06
Identities = 52/294 (17%), Positives = 121/294 (41%), Gaps = 11/294 (3%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSA-------LSRLEDKIRLIQDDLESERELRQR 56
MA + YR++ G D I L + L+ +E + L+Q ++E R ++
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL 116
ER + +++ SER++ S +K +T++ +++ +ED+ E+
Sbjct: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
Query: 117 LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKIT-ISKTCE 175
KK + + E++ + T A E+ K + V +L +++ + + K +
Sbjct: 1761 AKKAITDAAM-MAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1819
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+LE + EL ++E + + ++ + EL + ++ + NI + L ++ +
Sbjct: 1820 KLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQA 1879
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV--RVQLEEESEARLDLERQLV 287
+ A +++ +LE R + E +L ++ + V
Sbjct: 1880 KVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREV 1933
Score = 48.8 bits (111), Expect = 5e-05
Identities = 64/395 (16%), Positives = 142/395 (35%), Gaps = 4/395 (1%)
Query: 42 LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
L+++ E E+E + ++R + + +V Q + E + E +K+ + L+ +
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407
Query: 102 LLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
E V + + A L K K Q V D +++ A +K++ F + E +
Sbjct: 1408 --EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
E E K L + ++ EE + + + L QE +L +++ +
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 220 KVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR 279
I + +K Q+ + + +++++L V+ +++ + +
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 280 LDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNV 339
+ QL + + I K
Sbjct: 1586 DEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEA 1645
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
+ Q ++ I L+ A + +L+++ +ER +++ +EE EQT+R
Sbjct: 1646 LRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSR 1705
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + EL S + Q +L KK+ D+
Sbjct: 1706 KIAEQELLDASERVQLLHTQNTSLINTKKKLETDI 1740
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 248 bits (606), Expect = 5e-65
Identities = 143/463 (30%), Positives = 237/463 (51%), Gaps = 2/463 (0%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E+ ++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 49 IKELQARIEELEEEIEAERTSRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKR 108
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+ + E
Sbjct: 109 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 168
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E V+K K + K C LE +SE+ K EE R I D+T+ + RL Q +E
Sbjct: 169 IDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEY 228
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA-SLHQVEIDLESVRVQ 271
+++ D K +E + Q +Q A +L D + +R Q
Sbjct: 229 SRQL-DEKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 287
Query: 272 LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
EEE EA+ +L+R + KAN E+ WR+K+ K +
Sbjct: 288 YEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 347
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
+ AK ++EK K RLQ+EVE L+ID+E+ N L K+ +++ E K + EET +
Sbjct: 348 VNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETHAV 407
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXX 451
E Q++ R+ TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 408 LESFQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL 467
Query: 452 XXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 468 EKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVK 510
Score = 78.6 bits (185), Expect = 5e-14
Identities = 64/404 (15%), Positives = 167/404 (41%), Gaps = 6/404 (1%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + D + + + +++ + ++Q++E+EK+++ +++ L+ +E
Sbjct: 121 EATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVS 180
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + +L +++ K E L ++ TA + + Q+ +++ Q+D+
Sbjct: 181 KAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ--RARLQQNQVEYSRQLDEKDTL 238
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
+ + + K F ++ EL Q+E K K ++ + L + EE ++
Sbjct: 239 ETQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAEL 298
Query: 199 TSHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
+ + E + K D E + K ++A + +
Sbjct: 299 QRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKT 358
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+++ ++E + + +E + A L+++ + + W+ K
Sbjct: 359 KQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRS- 417
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S + ++ ++++ LQ E+ L + + EL+K +Q+E+
Sbjct: 418 LSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 477
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+++ LEE E + + Q E+ +V E+D+ +KD
Sbjct: 478 KSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKD 521
Score = 69.7 bits (163), Expect = 2e-11
Identities = 86/421 (20%), Positives = 173/421 (41%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE
Sbjct: 348 VNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETHAV 407
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQI-------DQ 134
ES + +R TEL K++ E+ L+ ET K Q+ + D EQI +
Sbjct: 408 LESFQKESRSLSTELFKIKNAYEE-SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 466
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVEN----VTKEKITISKTCERLEITISELHIKIEE 190
L K K + E+EKS+ QA + E A +E+ + + ++ +++ ++ I+E +I++
Sbjct: 467 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQ 526
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXX 250
+ R + I Q I + LK +E + +++ Q
Sbjct: 527 MKRNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDL---NEMEIQLNHANRMAAEDLRN 583
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
A L ++ L+ E+ E +ER+ EI R+
Sbjct: 584 YQNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIA 643
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
S +LI +E S++Q E+E +I + EKA +
Sbjct: 644 EQELLDA-SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITD 702
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 703 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAKVR 761
Query: 426 E 426
E
Sbjct: 762 E 762
Score = 56.8 bits (131), Expect = 2e-07
Identities = 81/429 (18%), Positives = 169/429 (39%), Gaps = 34/429 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
++E+ R ++++++++ L ++ + D + Q E E E AE Q ++ K ++
Sbjct: 252 QIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEE---EQEAKAELQRAMS-KANS 307
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
E+ + R E ++ E KKK + + D +E ++ + A EK K + Q EV
Sbjct: 308 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE 367
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL-- 212
+L+ VE + K + ++E K EE + + + LS E ++
Sbjct: 368 DLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKN 427
Query: 213 -----VKEVQDLKVNIENVVY----LKSQIAS---QXXXXXXXXXXXXXXXXXXXASLHQ 260
+ +++ LK +N+ L QIA + A+L +
Sbjct: 428 AYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEE 487
Query: 261 VEIDLES-----VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
E LE +R+QLE ++ + +++R++ + + EI +
Sbjct: 488 AEASLEHEEGKILRIQLEV-NQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEI 546
Query: 316 XKYSXXXXXXXXXXXTL------IAKINNVEKQKSRLQSEVEVLIID----LEKANGTAR 365
+ L + N + + R + ++ D L+ A +
Sbjct: 547 RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQE 606
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+++ +ER +++ +EE EQT+R + + EL S + Q +L
Sbjct: 607 DLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLIN 666
Query: 426 ENKKMGDDL 434
KK+ D+
Sbjct: 667 TKKKLETDI 675
Score = 50.8 bits (116), Expect = 1e-05
Identities = 37/192 (19%), Positives = 88/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ SER++ S +K
Sbjct: 612 LAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 671
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T++ +++ +ED+ E+ KK + + E++ + T A E+ K +
Sbjct: 672 ETDISQIQGEMEDIIKEARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 730
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + V+ + ++ E
Sbjct: 731 VKDLQHRLDEAEQLALKGGKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKE 790
Query: 212 LVKEVQDLKVNI 223
L + ++ + NI
Sbjct: 791 LTYQTEEDRKNI 802
Score = 43.2 bits (97), Expect = 0.002
Identities = 69/408 (16%), Positives = 156/408 (38%), Gaps = 44/408 (10%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGA-ESQFEINRKRDTELLKLRKLLEDV---- 106
++++++E+EK++L + + LE EG Q E+N+ + K+ + E++
Sbjct: 469 KIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMK 528
Query: 107 --HLESEET--------------AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
H+ EE+ A LKKK + + + + Q++ + A + Q
Sbjct: 529 RNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQ 588
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
A + + +++ + + + + +E + L +IEEL T+ ++ QE +
Sbjct: 589 AILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL 648
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
+ + VQ L +++ K ++ + + D +
Sbjct: 649 DASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAE 708
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
+L++E + LER + + + K
Sbjct: 709 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK------------- 755
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI----EIKSRLE 386
L AK+ +E + Q + L K +EL +TE+ +R NI ++ +L+
Sbjct: 756 -LEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQTEE-DRKNILRLQDLVDKLQ 813
Query: 387 ETVQLYEQTQRDLRNKQ----TELQRVSHELDKTREQKDALARENKKM 430
V+ Y++ + + ++ +R+ HEL++ E+ D + K+
Sbjct: 814 AKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKL 861
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 245 bits (600), Expect = 3e-64
Identities = 137/462 (29%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++D + ++ +LSERLEEA G +Q E+N+KR
Sbjct: 254 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 313
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E LKLR+ LE+ L+ E L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 314 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 373
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E+V+K K + K C LE +SE K EE+ R++ ++T+ K RL E EL
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 433
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + + + K Q +L D + +R Q
Sbjct: 434 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 493
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 494 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAV 553
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ EVE L++D+E+AN A L K+ ++V E K++ EE+
Sbjct: 554 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 613
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E + ++ R+ TEL ++ + ++ +Q + + RENK + ++ D I
Sbjct: 614 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 673
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAEA + EE + R+ E Q +
Sbjct: 674 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK 715
Score = 77.0 bits (181), Expect = 1e-13
Identities = 70/414 (16%), Positives = 165/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++ L + D + + + +++ + ++Q++E+EK++ +++ LS +E
Sbjct: 326 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +I R + +L + R E++ E K + Q + Q+++
Sbjct: 386 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT-TQKSRLQTEAGELSRQLEEKESIV 444
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K F + EL Q+E K K ++ + L + EE ++
Sbjct: 445 SQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL- 503
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + K ++A +
Sbjct: 504 --QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLE 561
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + V +E + L+++ + + W++K
Sbjct: 562 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 621
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S + ++ V+++ L+ E+ L + + T EL+K +Q+E
Sbjct: 622 S-LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 680
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+I+ LEE E + + Q EL +V E+D+ +KD + K+
Sbjct: 681 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKR 734
Score = 73.7 bits (173), Expect = 1e-12
Identities = 91/488 (18%), Positives = 200/488 (40%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ ++L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 33 LQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 92
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ +EK Q +
Sbjct: 93 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 151
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + +++KT +LE + +L +E+ + VD+ +K+ +L+QE+
Sbjct: 152 ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQES 211
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + Q+ S+ A + ++E ++E+
Sbjct: 212 ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 271
Query: 269 RVQLEEESEARLD-------LERQLVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R D L +L +A G E+ R ++F
Sbjct: 272 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 331
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++++ + + + K L
Sbjct: 332 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 391
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDA----LAREN 427
E++ ++ +L E E+ QR +L +++ LQ + EL + E+K++ L+R
Sbjct: 392 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 451
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + Y+E + G KAE QR+ +
Sbjct: 452 QAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQRALSKA 510
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 511 NSEVAQWR 518
Score = 72.5 bits (170), Expect = 3e-12
Identities = 84/414 (20%), Positives = 167/414 (40%), Gaps = 21/414 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL+ ++ + D+E L +++++ + + + + EE++
Sbjct: 553 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 612
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL KL+ E+ L+ ET K ++ + D EQI + KT
Sbjct: 613 LEASLKESRSLSTELFKLKNAYEEA-LDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 671
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + + E ++ +E E + + L I + +K E++R I +
Sbjct: 672 LEKSRKQIELEKADIQLALEEA--EAALEHEEAKILRIQLELTQVK-SEIDRKIAEKDEE 728
Query: 202 KQRLS---QENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++L Q +E ++ D +V N + LK ++
Sbjct: 729 IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKH 788
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGHWRSKFXXXXXXXXXX 310
L V+ L+ ++ L++ + DL+ QL +AN E+ R+
Sbjct: 789 LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 848
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ +LI +E +LQSEVE D EKA +
Sbjct: 849 EQELLDS-NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 907
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK
Sbjct: 908 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 960
Score = 66.1 bits (154), Expect = 3e-10
Identities = 96/439 (21%), Positives = 176/439 (40%), Gaps = 50/439 (11%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S+LE ++ ++ LE E++LR +ER K L + E + + E + E +K+D
Sbjct: 171 SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKD 230
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
E +L+ +ED E+T L +KK +E+ + + +E+I+ T+A+ EK++S +
Sbjct: 231 FEYCQLQSKVED-----EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 285
Query: 150 QAEVYELLAQVE---NVTKEKITISK------------------TCERLEITISELHI-K 187
E+ EL ++E VT +I ++K E + T+ + H
Sbjct: 286 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 345
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDL----------KVNIENVV-YLKSQIA-- 234
+ EL I ++ KQ+L +E E E+ DL K N+E + L+ Q++
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 235 ----SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+ L + + ES+ QL +A +L +
Sbjct: 406 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 465
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
E ++ +Y L + V + +++ +++
Sbjct: 466 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 525
Query: 351 EVLIIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
+LE+A A+ LQ EQ+E VN + S LE+T Q + DL +
Sbjct: 526 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVEDLMVDVERANSL 584
Query: 410 SHELDKTREQKDALARENK 428
+ LDK + D + E K
Sbjct: 585 AAALDKKQRNFDKVLAEWK 603
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ +ER++ S +K
Sbjct: 817 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKL 876
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T+L++L+ +ED ++ KK + + E++ + T A E+ K +
Sbjct: 877 ETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 935
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE I EL ++E + + ++ + E
Sbjct: 936 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 995
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 996 LTYQSEEDRKNV 1007
Score = 41.5 bits (93), Expect = 0.007
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 10/110 (9%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYE---LLAQVENVTKEKITISKTCERLEITISE 183
+FQ+ D+L K++A+ ++ + K V E L QV+ ++ + + C++L +
Sbjct: 1 EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQ 60
Query: 184 LHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENV 226
L KI+E+ D +T+ K++L E EL K++ DL++ + V
Sbjct: 61 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 110
Score = 41.1 bits (92), Expect = 0.009
Identities = 40/205 (19%), Positives = 92/205 (44%), Gaps = 13/205 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFE 87
S +L+D + D L + +L+++ +ER L +V +L LE+ E
Sbjct: 791 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------R 843
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + ELL + ++ +H ++ H KK ++ + Q +++ ++ AE++
Sbjct: 844 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL-MQLQSEVEDASRDARNAEEKAK 902
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLS 206
K + + +++ + + + LE T+ +L +++E + + + Q+L
Sbjct: 903 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 962
Query: 207 QENIELVKEVQ-DLKVNIENVVYLK 230
EL E++ + K N E+V L+
Sbjct: 963 TRIRELEFELEGEQKKNTESVKGLR 987
Score = 39.9 bits (89), Expect = 0.021
Identities = 75/426 (17%), Positives = 159/426 (37%), Gaps = 28/426 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------SQF 86
L + + + +L DDL S E + + KA+L L ++L EA G E S+
Sbjct: 363 LEKEKSEFKLEIDDLSSSME---SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 419
Query: 87 EINRKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKARA 142
+ R TE +L + LE E E L + Q +E Q+++ K K
Sbjct: 420 TTQKSRLQTEAGELSRQLE----EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 475
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE--LNRTIVDITS 200
+ + L Q E + K + + + +++ K E + RT ++
Sbjct: 476 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EELEE 534
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
K++L+Q + ++V+ + ++ K ++ +
Sbjct: 535 AKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 594
Query: 261 VEIDLESVRVQLEE---ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+ L + + EE E EA L R L ++ + + +
Sbjct: 595 FDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQE 654
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ T I+ +EK + +++ E + + LE+A + + +++
Sbjct: 655 IADLTEQIAENGKT----IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 710
Query: 378 NIEIKSRLEETV-QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++KS ++ + + E+ ++ RN Q ++ + LD ++ R KKM DL++
Sbjct: 711 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 770
Query: 437 ARANIT 442
++
Sbjct: 771 IEIQLS 776
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 245 bits (600), Expect = 3e-64
Identities = 137/462 (29%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++D + ++ +LSERLEEA G +Q E+N+KR
Sbjct: 1109 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 1168
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E LKLR+ LE+ L+ E L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1169 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1228
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E+V+K K + K C LE +SE K EE+ R++ ++T+ K RL E EL
Sbjct: 1229 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 1288
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + + + K Q +L D + +R Q
Sbjct: 1289 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 1348
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 1349 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAV 1408
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ EVE L++D+E+AN A L K+ ++V E K++ EE+
Sbjct: 1409 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E + ++ R+ TEL ++ + ++ +Q + + RENK + ++ D I
Sbjct: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 1528
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAEA + EE + R+ E Q +
Sbjct: 1529 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK 1570
Score = 75.4 bits (177), Expect = 5e-13
Identities = 69/414 (16%), Positives = 165/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++ L + D + + + +++ + ++Q++E+EK++ +++ LS +E
Sbjct: 1181 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 1240
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +I R + +L + R E++ E K + Q + Q+++
Sbjct: 1241 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT-TQKSRLQTEAGELSRQLEEKESIV 1299
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K F + EL Q+E K K ++ + L + EE ++
Sbjct: 1300 SQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL- 1358
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + + ++A +
Sbjct: 1359 --QRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLE 1416
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + V +E + L+++ + + W++K
Sbjct: 1417 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 1476
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S + ++ V+++ L+ E+ L + + T EL+K +Q+E
Sbjct: 1477 S-LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 1535
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+I+ LEE E + + Q EL +V E+D+ +KD + K+
Sbjct: 1536 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKR 1589
Score = 73.7 bits (173), Expect = 1e-12
Identities = 91/488 (18%), Positives = 200/488 (40%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ ++L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 888 LQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 947
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ +EK Q +
Sbjct: 948 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 1006
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + +++KT +LE + +L +E+ + VD+ +K+ +L+QE+
Sbjct: 1007 ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQES 1066
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + Q+ S+ A + ++E ++E+
Sbjct: 1067 ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 1126
Query: 269 RVQLEEESEARLD-------LERQLVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R D L +L +A G E+ R ++F
Sbjct: 1127 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 1186
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++++ + + + K L
Sbjct: 1187 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 1246
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDA----LAREN 427
E++ ++ +L E E+ QR +L +++ LQ + EL + E+K++ L+R
Sbjct: 1247 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 1306
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + Y+E + G KAE QR+ +
Sbjct: 1307 QAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQRALSKA 1365
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 1366 NSEVAQWR 1373
Score = 72.5 bits (170), Expect = 3e-12
Identities = 84/414 (20%), Positives = 167/414 (40%), Gaps = 21/414 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL+ ++ + D+E L +++++ + + + + EE++
Sbjct: 1408 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 1467
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL KL+ E+ L+ ET K ++ + D EQI + KT
Sbjct: 1468 LEASLKESRSLSTELFKLKNAYEEA-LDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 1526
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + + E ++ +E E + + L I + +K E++R I +
Sbjct: 1527 LEKSRKQIELEKADIQLALEEA--EAALEHEEAKILRIQLELTQVK-SEIDRKIAEKDEE 1583
Query: 202 KQRLS---QENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++L Q +E ++ D +V N + LK ++
Sbjct: 1584 IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKH 1643
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGHWRSKFXXXXXXXXXX 310
L V+ L+ ++ L++ + DL+ QL +AN E+ R+
Sbjct: 1644 LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 1703
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ +LI +E +LQSEVE D EKA +
Sbjct: 1704 EQELLDS-NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 1762
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK
Sbjct: 1763 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1815
Score = 66.1 bits (154), Expect = 3e-10
Identities = 96/439 (21%), Positives = 176/439 (40%), Gaps = 50/439 (11%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S+LE ++ ++ LE E++LR +ER K L + E + + E + E +K+D
Sbjct: 1026 SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKD 1085
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
E +L+ +ED E+T L +KK +E+ + + +E+I+ T+A+ EK++S +
Sbjct: 1086 FEYCQLQSKVED-----EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 150 QAEVYELLAQVE---NVTKEKITISK------------------TCERLEITISELHI-K 187
E+ EL ++E VT +I ++K E + T+ + H
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 1200
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDL----------KVNIENVV-YLKSQIA-- 234
+ EL I ++ KQ+L +E E E+ DL K N+E + L+ Q++
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 235 ----SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+ L + + ES+ QL +A +L +
Sbjct: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
E ++ +Y L + V + +++ +++
Sbjct: 1321 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 1380
Query: 351 EVLIIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
+LE+A A+ LQ EQ+E VN + S LE+T Q + DL +
Sbjct: 1381 IQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVEDLMVDVERANSL 1439
Query: 410 SHELDKTREQKDALARENK 428
+ LDK + D + E K
Sbjct: 1440 AAALDKKQRNFDKVLAEWK 1458
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ +ER++ S +K
Sbjct: 1672 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKL 1731
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T+L++L+ +ED ++ KK + + E++ + T A E+ K +
Sbjct: 1732 ETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1790
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE I EL ++E + + ++ + E
Sbjct: 1791 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 1850
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 1851 LTYQSEEDRKNV 1862
Score = 41.5 bits (93), Expect = 0.007
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 10/110 (9%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYE---LLAQVENVTKEKITISKTCERLEITISE 183
+FQ+ D+L K++A+ ++ + K V E L QV+ ++ + + C++L +
Sbjct: 856 EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQ 915
Query: 184 LHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENV 226
L KI+E+ D +T+ K++L E EL K++ DL++ + V
Sbjct: 916 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 965
Score = 41.1 bits (92), Expect = 0.009
Identities = 40/205 (19%), Positives = 92/205 (44%), Gaps = 13/205 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFE 87
S +L+D + D L + +L+++ +ER L +V +L LE+ E
Sbjct: 1646 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------R 1698
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + ELL + ++ +H ++ H KK ++ + Q +++ ++ AE++
Sbjct: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL-MQLQSEVEDASRDARNAEEKAK 1757
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLS 206
K + + +++ + + + LE T+ +L +++E + + + Q+L
Sbjct: 1758 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1817
Query: 207 QENIELVKEVQ-DLKVNIENVVYLK 230
EL E++ + K N E+V L+
Sbjct: 1818 TRIRELEFELEGEQKKNTESVKGLR 1842
Score = 38.7 bits (86), Expect = 0.048
Identities = 74/426 (17%), Positives = 159/426 (37%), Gaps = 28/426 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------SQF 86
L + + + +L DDL S E + + KA+L L ++L EA G E S+
Sbjct: 1218 LEKEKSEFKLEIDDLSSSME---SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 1274
Query: 87 EINRKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKARA 142
+ R TE +L + LE E E L + Q +E Q+++ K K
Sbjct: 1275 TTQKSRLQTEAGELSRQLE----EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 1330
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE--LNRTIVDITS 200
+ + L Q E + K + + + +++ K E + RT ++
Sbjct: 1331 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EELEE 1389
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+++L+Q + ++V+ + ++ K ++ +
Sbjct: 1390 AQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 1449
Query: 261 VEIDLESVRVQLEE---ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+ L + + EE E EA L R L ++ + + +
Sbjct: 1450 FDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQE 1509
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ T I+ +EK + +++ E + + LE+A + + +++
Sbjct: 1510 IADLTEQIAENGKT----IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 1565
Query: 378 NIEIKSRLEETV-QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++KS ++ + + E+ ++ RN Q ++ + LD ++ R KKM DL++
Sbjct: 1566 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 1625
Query: 437 ARANIT 442
++
Sbjct: 1626 IEIQLS 1631
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 245 bits (600), Expect = 3e-64
Identities = 137/462 (29%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++D + ++ +LSERLEEA G +Q E+N+KR
Sbjct: 336 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 395
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E LKLR+ LE+ L+ E L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 396 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 455
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E+V+K K + K C LE +SE K EE+ R++ ++T+ K RL E EL
Sbjct: 456 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 515
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + + + K Q +L D + +R Q
Sbjct: 516 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 575
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 576 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAV 635
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ EVE L++D+E+AN A L K+ ++V E K++ EE+
Sbjct: 636 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 695
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E + ++ R+ TEL ++ + ++ +Q + + RENK + ++ D I
Sbjct: 696 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 755
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAEA + EE + R+ E Q +
Sbjct: 756 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK 797
Score = 75.4 bits (177), Expect = 5e-13
Identities = 69/414 (16%), Positives = 165/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++ L + D + + + +++ + ++Q++E+EK++ +++ LS +E
Sbjct: 408 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 467
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +I R + +L + R E++ E K + Q + Q+++
Sbjct: 468 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT-TQKSRLQTEAGELSRQLEEKESIV 526
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K F + EL Q+E K K ++ + L + EE ++
Sbjct: 527 SQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL- 585
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + + ++A +
Sbjct: 586 --QRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLE 643
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + V +E + L+++ + + W++K
Sbjct: 644 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 703
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S + ++ V+++ L+ E+ L + + T EL+K +Q+E
Sbjct: 704 S-LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 762
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+I+ LEE E + + Q EL +V E+D+ +KD + K+
Sbjct: 763 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKR 816
Score = 73.7 bits (173), Expect = 1e-12
Identities = 91/488 (18%), Positives = 200/488 (40%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ ++L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 115 LQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 174
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ +EK Q +
Sbjct: 175 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 233
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + +++KT +LE + +L +E+ + VD+ +K+ +L+QE+
Sbjct: 234 ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQES 293
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + Q+ S+ A + ++E ++E+
Sbjct: 294 ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 353
Query: 269 RVQLEEESEARLD-------LERQLVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R D L +L +A G E+ R ++F
Sbjct: 354 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 413
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++++ + + + K L
Sbjct: 414 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 473
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDA----LAREN 427
E++ ++ +L E E+ QR +L +++ LQ + EL + E+K++ L+R
Sbjct: 474 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 533
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + Y+E + G KAE QR+ +
Sbjct: 534 QAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG-KAELQRALSKA 592
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 593 NSEVAQWR 600
Score = 73.3 bits (172), Expect = 2e-12
Identities = 84/414 (20%), Positives = 168/414 (40%), Gaps = 21/414 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL+ ++ + D+E L +++++ + + + + EE++
Sbjct: 635 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 694
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL KL+ E+ L+ ET K ++ + D EQI + KT
Sbjct: 695 LEASLKESRSLSTELFKLKNAYEEA-LDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 753
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + + E ++ +E E + + L I + +K E++R I +
Sbjct: 754 LEKSRKQIELEKADIQLALEEA--EAALEHEEAKILRIQLELTQVK-SEIDRKIAEKDEE 810
Query: 202 KQRLS---QENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++L Q +E ++ D +V N + LK ++
Sbjct: 811 IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKH 870
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGHWRSKFXXXXXXXXXX 310
L V+ L+ ++ L++ + + DL+ QL +AN E+ R+
Sbjct: 871 LRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 930
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ +LI +E +LQSEVE D EKA +
Sbjct: 931 EQELLDS-NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 989
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK
Sbjct: 990 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1042
Score = 66.1 bits (154), Expect = 3e-10
Identities = 96/439 (21%), Positives = 176/439 (40%), Gaps = 50/439 (11%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S+LE ++ ++ LE E++LR +ER K L + E + + E + E +K+D
Sbjct: 253 SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKD 312
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
E +L+ +ED E+T L +KK +E+ + + +E+I+ T+A+ EK++S +
Sbjct: 313 FEYCQLQSKVED-----EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 367
Query: 150 QAEVYELLAQVE---NVTKEKITISK------------------TCERLEITISELHI-K 187
E+ EL ++E VT +I ++K E + T+ + H
Sbjct: 368 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 427
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDL----------KVNIENVV-YLKSQIA-- 234
+ EL I ++ KQ+L +E E E+ DL K N+E + L+ Q++
Sbjct: 428 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 487
Query: 235 ----SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+ L + + ES+ QL +A +L +
Sbjct: 488 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 547
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
E ++ +Y L + V + +++ +++
Sbjct: 548 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 607
Query: 351 EVLIIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
+LE+A A+ LQ EQ+E VN + S LE+T Q + DL +
Sbjct: 608 IQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVEDLMVDVERANSL 666
Query: 410 SHELDKTREQKDALARENK 428
+ LDK + D + E K
Sbjct: 667 AAALDKKQRNFDKVLAEWK 685
Score = 57.6 bits (133), Expect = 1e-07
Identities = 76/433 (17%), Positives = 166/433 (38%), Gaps = 32/433 (7%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ R ++++ +++ L ++ + D + Q E E EG AE Q ++ K ++E+
Sbjct: 541 EELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEE---EQEGKAELQRALS-KANSEV 596
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ R E ++ E ++K + + D +EQ++ + A EK K + Q EV +L
Sbjct: 597 AQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDL 656
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ VE + K + ++E K EE + + LS E +L
Sbjct: 657 MVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY 716
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-------LESVR 269
++ +E V + + S Q+E++ LE
Sbjct: 717 EEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE 776
Query: 270 VQLEEE-----------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
LE E ++ + +++R++ + + EI + +
Sbjct: 777 AALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSR 836
Query: 319 SXXXXXXXXXXXTLIA---KINNVEKQKSR-------LQSEVEVLIIDLEKANGTARELQ 368
+ L ++++ +Q + +Q +++ + L+ A T +L+
Sbjct: 837 NEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLK 896
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
++ +ER +++ +EE EQT+R + + EL + + Q +L K
Sbjct: 897 EQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKK 956
Query: 429 KMGDDLHDARANI 441
K+ DL ++ +
Sbjct: 957 KLETDLMQLQSEV 969
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ +ER++ S +K
Sbjct: 899 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKL 958
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T+L++L+ +ED ++ KK + + E++ + T A E+ K +
Sbjct: 959 ETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1017
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE I EL ++E + + ++ + E
Sbjct: 1018 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 1077
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 1078 LTYQSEEDRKNV 1089
Score = 42.3 bits (95), Expect = 0.004
Identities = 40/205 (19%), Positives = 94/205 (45%), Gaps = 13/205 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFE 87
S +L+D + D L+++ +L+++ +ER L +V +L LE+ E
Sbjct: 873 SVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------R 925
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + ELL + ++ +H ++ H KK ++ + Q +++ ++ AE++
Sbjct: 926 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL-MQLQSEVEDASRDARNAEEKAK 984
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLS 206
K + + +++ + + + LE T+ +L +++E + + + Q+L
Sbjct: 985 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1044
Query: 207 QENIELVKEVQ-DLKVNIENVVYLK 230
EL E++ + K N E+V L+
Sbjct: 1045 TRIRELEFELEGEQKKNTESVKGLR 1069
Score = 41.5 bits (93), Expect = 0.007
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 10/110 (9%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYE---LLAQVENVTKEKITISKTCERLEITISE 183
+FQ+ D+L K++A+ ++ + K V E L QV+ ++ + + C++L +
Sbjct: 83 EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQ 142
Query: 184 LHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENV 226
L KI+E+ D +T+ K++L E EL K++ DL++ + V
Sbjct: 143 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 192
Score = 38.7 bits (86), Expect = 0.048
Identities = 74/426 (17%), Positives = 159/426 (37%), Gaps = 28/426 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------SQF 86
L + + + +L DDL S E + + KA+L L ++L EA G E S+
Sbjct: 445 LEKEKSEFKLEIDDLSSSME---SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 501
Query: 87 EINRKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKARA 142
+ R TE +L + LE E E L + Q +E Q+++ K K
Sbjct: 502 TTQKSRLQTEAGELSRQLE----EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 557
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE--LNRTIVDITS 200
+ + L Q E + K + + + +++ K E + RT ++
Sbjct: 558 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EELEE 616
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+++L+Q + ++V+ + ++ K ++ +
Sbjct: 617 AQEKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 676
Query: 261 VEIDLESVRVQLEE---ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+ L + + EE E EA L R L ++ + + +
Sbjct: 677 FDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQE 736
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ T I+ +EK + +++ E + + LE+A + + +++
Sbjct: 737 IADLTEQIAENGKT----IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 792
Query: 378 NIEIKSRLEETV-QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++KS ++ + + E+ ++ RN Q ++ + LD ++ R KKM DL++
Sbjct: 793 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 852
Query: 437 ARANIT 442
++
Sbjct: 853 IEIQLS 858
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 245 bits (600), Expect = 3e-64
Identities = 137/462 (29%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++D + ++ +LSERLEEA G +Q E+N+KR
Sbjct: 110 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 169
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E LKLR+ LE+ L+ E L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 170 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 229
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E+V+K K + K C LE +SE K EE+ R++ ++T+ K RL E EL
Sbjct: 230 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 289
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + + + K Q +L D + +R Q
Sbjct: 290 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQY 349
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 350 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAV 409
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ EVE L++D+E+AN A L K+ ++V E K++ EE+
Sbjct: 410 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 469
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E + ++ R+ TEL ++ + ++ +Q + + RENK + ++ D I
Sbjct: 470 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 529
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAEA + EE + R+ E Q +
Sbjct: 530 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK 571
Score = 77.0 bits (181), Expect = 1e-13
Identities = 70/414 (16%), Positives = 165/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++ L + D + + + +++ + ++Q++E+EK++ +++ LS +E
Sbjct: 182 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 241
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +I R + +L + R E++ E K + Q + Q+++
Sbjct: 242 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT-TQKSRLQTEAGELSRQLEEKESIV 300
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K F + EL Q+E K K ++ + L + EE ++
Sbjct: 301 SQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL- 359
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + K ++A +
Sbjct: 360 --QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLE 417
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + V +E + L+++ + + W++K
Sbjct: 418 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 477
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S + ++ V+++ L+ E+ L + + T EL+K +Q+E
Sbjct: 478 S-LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 536
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+I+ LEE E + + Q EL +V E+D+ +KD + K+
Sbjct: 537 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKR 590
Score = 72.5 bits (170), Expect = 3e-12
Identities = 84/414 (20%), Positives = 167/414 (40%), Gaps = 21/414 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL+ ++ + D+E L +++++ + + + + EE++
Sbjct: 409 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 468
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL KL+ E+ L+ ET K ++ + D EQI + KT
Sbjct: 469 LEASLKESRSLSTELFKLKNAYEEA-LDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 527
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + + E ++ +E E + + L I + +K E++R I +
Sbjct: 528 LEKSRKQIELEKADIQLALEEA--EAALEHEEAKILRIQLELTQVK-SEIDRKIAEKDEE 584
Query: 202 KQRLS---QENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++L Q +E ++ D +V N + LK ++
Sbjct: 585 IEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKH 644
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGHWRSKFXXXXXXXXXX 310
L V+ L+ ++ L++ + DL+ QL +AN E+ R+
Sbjct: 645 LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 704
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ +LI +E +LQSEVE D EKA +
Sbjct: 705 EQELLDS-NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 763
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK
Sbjct: 764 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 816
Score = 66.1 bits (154), Expect = 3e-10
Identities = 96/439 (21%), Positives = 176/439 (40%), Gaps = 50/439 (11%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S+LE ++ ++ LE E++LR +ER K L + E + + E + E +K+D
Sbjct: 27 SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKD 86
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
E +L+ +ED E+T L +KK +E+ + + +E+I+ T+A+ EK++S +
Sbjct: 87 FEYCQLQSKVED-----EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 141
Query: 150 QAEVYELLAQVE---NVTKEKITISK------------------TCERLEITISELHI-K 187
E+ EL ++E VT +I ++K E + T+ + H
Sbjct: 142 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 201
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDL----------KVNIENVV-YLKSQIA-- 234
+ EL I ++ KQ+L +E E E+ DL K N+E + L+ Q++
Sbjct: 202 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 261
Query: 235 ----SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+ L + + ES+ QL +A +L +
Sbjct: 262 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 321
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
E ++ +Y L + V + +++ +++
Sbjct: 322 EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 381
Query: 351 EVLIIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
+LE+A A+ LQ EQ+E VN + S LE+T Q + DL +
Sbjct: 382 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVEDLMVDVERANSL 440
Query: 410 SHELDKTREQKDALARENK 428
+ LDK + D + E K
Sbjct: 441 AAALDKKQRNFDKVLAEWK 459
Score = 55.2 bits (127), Expect = 5e-07
Identities = 73/387 (18%), Positives = 153/387 (39%), Gaps = 22/387 (5%)
Query: 117 LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCER 176
L++ +Q+ + D Q + D++ K KSK + +V +L + +E K ++ + + +
Sbjct: 1 LQEAHQQALDDLQAEEDKVNSLN----KTKSKLEQQVEDLESSLEQEKKLRVDLERNKRK 56
Query: 177 LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQ 236
LE +L + E +I+D+ + KQ+L + + E L+ +E+ L Q +
Sbjct: 57 LE---GDLKLAQE----SILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKK 109
Query: 237 XXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHW 296
A+ + E +LEE SE RL+ + E+
Sbjct: 110 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSE-RLEEAGGVTSTQIELNKK 168
Query: 297 R-SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLII 355
R ++F + L +I+N+++ K +L+ E +
Sbjct: 169 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 228
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHE 412
+++ + + + K LE++ ++ +L E E+ QR +L +++ LQ + E
Sbjct: 229 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGE 288
Query: 413 LDKTREQKDA----LARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAA 468
L + E+K++ L+R + + + +
Sbjct: 289 LSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQ 348
Query: 469 YKEAEAGRKAEEQRS-QRLTAEFGQFR 494
Y+E + G KAE QR+ + +E Q+R
Sbjct: 349 YEEEQEG-KAELQRALSKANSEVAQWR 374
Score = 54.8 bits (126), Expect = 7e-07
Identities = 72/402 (17%), Positives = 154/402 (38%), Gaps = 10/402 (2%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELLKLRKLL 103
DDL++E + + + K+ L QV L LE+ E E N RK + +L ++ +
Sbjct: 10 DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ-EKKLRVDLERNKRKLEGDLKLAQESI 68
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
D+ + ++ LKKK+ E Q +++ + +K+ + QA + EL ++E
Sbjct: 69 LDLENDKQQLDERLKKKDFE-YCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 127
Query: 164 TKEKITISKTCERLEITISELHIKIEELNR-TIVDITSHKQRLSQENIELVKEVQDLKVN 222
+ K + EL ++EE T I +K+R E ++L +++++ +
Sbjct: 128 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR-EAEFLKLRRDLEEATLQ 186
Query: 223 IENVV-YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
E +V L+ + A + +++++ + +E S+++ +
Sbjct: 187 HEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 246
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
LE+ ++ R K + + ++ + +
Sbjct: 247 LEKICRTLEDQLSEARGK-NEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSR 305
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
K + E L LE+ N L + ++ + EE + + QR L
Sbjct: 306 SKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSK 365
Query: 402 KQTELQ--RVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+E+ R +E D ++ + L KK+ L D+ +
Sbjct: 366 ANSEVAQWRTKYETDAI-QRTEELEEAKKKLAQRLQDSEEQV 406
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ +ER++ S +K
Sbjct: 673 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKL 732
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T+L++L+ +ED ++ KK + + E++ + T A E+ K +
Sbjct: 733 ETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 791
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE I EL ++E + + ++ + E
Sbjct: 792 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 851
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 852 LTYQSEEDRKNV 863
Score = 41.1 bits (92), Expect = 0.009
Identities = 40/205 (19%), Positives = 92/205 (44%), Gaps = 13/205 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFE 87
S +L+D + D L + +L+++ +ER L +V +L LE+ E
Sbjct: 647 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------R 699
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + ELL + ++ +H ++ H KK ++ + Q +++ ++ AE++
Sbjct: 700 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL-MQLQSEVEDASRDARNAEEKAK 758
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLS 206
K + + +++ + + + LE T+ +L +++E + + + Q+L
Sbjct: 759 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 818
Query: 207 QENIELVKEVQ-DLKVNIENVVYLK 230
EL E++ + K N E+V L+
Sbjct: 819 TRIRELEFELEGEQKKNTESVKGLR 843
Score = 39.9 bits (89), Expect = 0.021
Identities = 75/426 (17%), Positives = 159/426 (37%), Gaps = 28/426 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------SQF 86
L + + + +L DDL S E + + KA+L L ++L EA G E S+
Sbjct: 219 LEKEKSEFKLEIDDLSSSME---SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 275
Query: 87 EINRKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKARA 142
+ R TE +L + LE E E L + Q +E Q+++ K K
Sbjct: 276 TTQKSRLQTEAGELSRQLE----EKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNAL 331
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE--LNRTIVDITS 200
+ + L Q E + K + + + +++ K E + RT ++
Sbjct: 332 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EELEE 390
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
K++L+Q + ++V+ + ++ K ++ +
Sbjct: 391 AKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 450
Query: 261 VEIDLESVRVQLEE---ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+ L + + EE E EA L R L ++ + + +
Sbjct: 451 FDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQE 510
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ T I+ +EK + +++ E + + LE+A + + +++
Sbjct: 511 IADLTEQIAENGKT----IHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLE 566
Query: 378 NIEIKSRLEETV-QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++KS ++ + + E+ ++ RN Q ++ + LD ++ R KKM DL++
Sbjct: 567 LTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNE 626
Query: 437 ARANIT 442
++
Sbjct: 627 IEIQLS 632
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 245 bits (599), Expect = 3e-64
Identities = 137/462 (29%), Positives = 235/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++D + ++ +LSERLEEA G +Q E+N+KR
Sbjct: 254 IKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKR 313
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E LKLR+ LE+ L+ E L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 314 EAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 373
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E+V+K K + K C LE +SE K EE+ R++ ++T+ K RL E EL
Sbjct: 374 IDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 433
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + + + K Q +L D + +R Q
Sbjct: 434 SRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQY 493
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 494 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAV 553
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ EVE L++D+E+AN A L K+ ++V E K++ EE+
Sbjct: 554 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 613
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E + ++ R+ TEL ++ + ++ +Q + + RENK + ++ D I
Sbjct: 614 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 673
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAEA + EE + R+ E Q +
Sbjct: 674 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVK 715
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/414 (16%), Positives = 164/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++ L + D + + + +++ + ++Q++E+EK++ +++ LS +E
Sbjct: 326 EATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +I R + +L + R E++ E K + Q + Q+++
Sbjct: 386 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT-TQKSRLQTEAGELSRQLEEKESIV 444
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K F + EL Q+E K K + + L + EE ++
Sbjct: 445 SQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAEL- 503
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + K ++A +
Sbjct: 504 --QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLE 561
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + V +E + L+++ + + W++K
Sbjct: 562 KTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESR 621
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S + ++ V+++ L+ E+ L + + T EL+K +Q+E
Sbjct: 622 S-LSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIE 680
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+I+ LEE E + + Q EL +V E+D+ +KD + K+
Sbjct: 681 LEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKR 734
Score = 73.3 bits (172), Expect = 2e-12
Identities = 91/488 (18%), Positives = 200/488 (40%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ ++L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 33 LQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 92
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ +EK Q +
Sbjct: 93 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 151
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + +++KT +LE + +L +E+ + VD+ +K+ +L+QE+
Sbjct: 152 ALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQES 211
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
I +L + Q L ++ + Q+ S+ A + ++E ++E+
Sbjct: 212 ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAE 271
Query: 269 RVQLEEESEARLD-------LERQLVKANG------EIGHWR-SKFXXXXXXXXXXXXXX 314
R + + R D L +L +A G E+ R ++F
Sbjct: 272 RATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQH 331
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ L +I+N+++ K +L+ E ++++ + + + K L
Sbjct: 332 EAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 391
Query: 375 ERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDA----LAREN 427
E++ ++ +L E E+ QR +L +++ LQ + EL + E+K++ L+R
Sbjct: 392 EKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSK 451
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + Y+E + G KAE QR+ +
Sbjct: 452 QAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEG-KAELQRALSKA 510
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 511 NSEVAQWR 518
Score = 71.7 bits (168), Expect = 6e-12
Identities = 84/414 (20%), Positives = 167/414 (40%), Gaps = 21/414 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL+ ++ + D+E L +++++ + + + + EE++
Sbjct: 553 VNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE 612
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL KL+ E+ L+ ET K ++ + D EQI + KT
Sbjct: 613 LEASLKESRSLSTELFKLKNAYEEA-LDQLETVKRENKNLEQEIADLTEQIAENGKTIHE 671
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + + E ++ +E E + + L I + +K E++R I +
Sbjct: 672 LEKSRKQIELEKADIQLALEEA--EAALEHEEAKILRIQLELTQVK-SEIDRKIAEKDEE 728
Query: 202 KQRLS---QENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++L Q +E ++ D +V N + LK ++
Sbjct: 729 IEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKH 788
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGHWRSKFXXXXXXXXXX 310
L V+ L+ ++ L++ + DL+ QL +AN E+ R+
Sbjct: 789 LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLA 848
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ +LI +E +LQSEVE D EKA +
Sbjct: 849 EQELLDS-NERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITD 907
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK
Sbjct: 908 AAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 960
Score = 65.7 bits (153), Expect = 4e-10
Identities = 96/439 (21%), Positives = 176/439 (40%), Gaps = 50/439 (11%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S+LE ++ ++ LE E++LR +ER K L + E + + E + E +K+D
Sbjct: 171 SKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKD 230
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
E +L+ +ED E+T L +KK +E+ + + +E+I+ T+A+ EK++S +
Sbjct: 231 FEYCQLQSKVED-----EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 285
Query: 150 QAEVYELLAQVE---NVTKEKITISK------------------TCERLEITISELHI-K 187
E+ EL ++E VT +I ++K E + T+ + H
Sbjct: 286 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADS 345
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDL----------KVNIENVV-YLKSQIA-- 234
+ EL I ++ KQ+L +E E E+ DL K N+E + L+ Q++
Sbjct: 346 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 405
Query: 235 ----SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+ L + + ES+ QL +A +L +
Sbjct: 406 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 465
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
E ++ +Y L + V + +++ +++
Sbjct: 466 EEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDA 525
Query: 351 EVLIIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
+LE+A A+ LQ EQ+E VN + S LE+T Q + DL +
Sbjct: 526 IQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS-LEKTKQRLQGEVEDLMVDVERANSL 584
Query: 410 SHELDKTREQKDALARENK 428
+ LDK + D + E K
Sbjct: 585 AAALDKKQRNFDKVLAEWK 603
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R ++ ER + +++ +ER++ S +K
Sbjct: 817 LAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKL 876
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T+L++L+ +ED ++ KK + + E++ + T A E+ K +
Sbjct: 877 ETDLMQLQSEVEDASRDARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 935
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE I EL ++E + + ++ + E
Sbjct: 936 VKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKE 995
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 996 LTYQSEEDRKNV 1007
Score = 41.5 bits (93), Expect = 0.007
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 10/110 (9%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYE---LLAQVENVTKEKITISKTCERLEITISE 183
+FQ+ D+L K++A+ ++ + K V E L QV+ ++ + + C++L +
Sbjct: 1 EFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQ 60
Query: 184 LHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENV 226
L KI+E+ D +T+ K++L E EL K++ DL++ + V
Sbjct: 61 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKV 110
Score = 41.1 bits (92), Expect = 0.009
Identities = 40/205 (19%), Positives = 92/205 (44%), Gaps = 13/205 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFE 87
S +L+D + D L + +L+++ +ER L +V +L LE+ E
Sbjct: 791 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTE-------R 843
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + ELL + ++ +H ++ H KK ++ + Q +++ ++ AE++
Sbjct: 844 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL-MQLQSEVEDASRDARNAEEKAK 902
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLS 206
K + + +++ + + + LE T+ +L +++E + + + Q+L
Sbjct: 903 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 962
Query: 207 QENIELVKEVQ-DLKVNIENVVYLK 230
EL E++ + K N E+V L+
Sbjct: 963 TRIRELEFELEGEQKKNTESVKGLR 987
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 242 bits (593), Expect = 2e-63
Identities = 134/462 (29%), Positives = 236/462 (51%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L + +I ++++LE+ER R ++E+ ++DLS ++ ++SERLEEA G Q E+N+KR
Sbjct: 1110 LKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR 1169
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + EQID L + K + EKEKS+F+ E
Sbjct: 1170 EAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1229
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E + K K + K LE +E +K+EE R++ D T+ + +L EN EL
Sbjct: 1230 LDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGEL 1289
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++++ + I + K Q +L D + +R Q
Sbjct: 1290 SRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQY 1349
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ R+K+ K + +
Sbjct: 1350 EEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAV 1409
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+
Sbjct: 1410 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1469
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 1470 ESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELE 1529
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIK 1571
Score = 76.6 bits (180), Expect = 2e-13
Identities = 88/413 (21%), Positives = 179/413 (43%), Gaps = 27/413 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ QD+L E ++ + K L +V +++ERLE+ E RK + E
Sbjct: 889 LQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDE 948
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L + A+ KEK Q +
Sbjct: 949 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L ++ + T+SK+ +LE + +L +E+ + +D+ K++L + +++L +E
Sbjct: 1008 ALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL-EGDLKLTQE 1066
Query: 216 -VQDL---KVNIENVVYLK----SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
+ DL K+ +E + K +Q S+ A + ++E +LE+
Sbjct: 1067 SIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEA 1126
Query: 268 VRVQLEEESEARLDLERQ-------LVKANG------EIGHWR-SKFXXXXXXXXXXXXX 313
R + + R DL R+ L +A G E+ R ++F
Sbjct: 1127 ERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1186
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ L +I+N+++ K +L+ E ++L+ ++ K
Sbjct: 1187 HEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN 1246
Query: 374 LERVNIEIKSRLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDAL 423
LE+V+ ++ + E E+ QR D ++ +LQ + EL + E+K+AL
Sbjct: 1247 LEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEAL 1299
Score = 74.5 bits (175), Expect = 8e-13
Identities = 63/411 (15%), Positives = 162/411 (39%), Gaps = 4/411 (0%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A +AL + D + + + +++ + ++Q++E+EK++ +++ ++ +E+
Sbjct: 1182 EATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQII 1241
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ +++R + + + R LE+ + K E + Q+++
Sbjct: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENG-ELSRQLEEKEALI 1300
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ + K + ++ +L Q+E K K ++ + L + EE ++
Sbjct: 1301 SQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Query: 200 SHKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ + E + K D E + K ++A + +
Sbjct: 1361 RVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTK 1420
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 1421 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 1479
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + EL+K +QLE
Sbjct: 1480 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEK 1539
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 1540 LELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 1590
Score = 64.9 bits (151), Expect = 6e-10
Identities = 74/415 (17%), Positives = 156/415 (37%), Gaps = 10/415 (2%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINR 90
AL L+++ E E E + ++R + + +V Q + E +A E E +
Sbjct: 1334 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKK 1393
Query: 91 KRDTELLKLRKLLEDVHLES---EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
K L + +E V+ + E+T H L+ + +++++D +++ A +K++
Sbjct: 1394 KLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQR 1449
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
F + E + E E + K L + +L EE + + L +
Sbjct: 1450 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 1509
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +L +++ + N+ + ++ Q+ + + + +++
Sbjct: 1510 EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQ 1569
Query: 268 VRVQLEEESEARLDLERQLVKANGE-IGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ ++E + A D E + K N + + K
Sbjct: 1570 IKAEIERKL-AEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KQ LQS ++ I L+ A +L++ +ER N +++ LE
Sbjct: 1629 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1688
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + EQT+R + EL S + Q +L + KKM DL ++ +
Sbjct: 1689 ELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEV 1743
Score = 62.9 bits (146), Expect = 3e-09
Identities = 85/419 (20%), Positives = 177/419 (42%), Gaps = 42/419 (10%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ I++ LE R+ +E +EK DL +QV + L +AE +
Sbjct: 851 MATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQL 910
Query: 86 FEINRKRDTELLKLRKLLED-VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
+ + + ++ ++ + LED + +E TA K+K ++ + ++ ID L T A+ EK
Sbjct: 911 IKNKIQLEAKVKEMNERLEDEEEMNAELTAK--KRKLEDECSELKKDIDDLELTLAKVEK 968
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQ 203
EK + +V L ++ + ++I T E+ + E H + +++L + +
Sbjct: 969 EKHATENKVKNLTEEMAGL--DEIIAKLTKEKK--ALQEAHQQALDDLQAEEDKVNT--- 1021
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
LS+ ++L ++V DL+ ++E ++ + + ++E
Sbjct: 1022 -LSKSKVKLEQQVDDLEGSLEQEKKVRMDL---------------------ERAKRKLEG 1059
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
DL+ + + + +L LE +L K +I SK +
Sbjct: 1060 DLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEE 1119
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A+ VEK +S L E+E + LE+A G + ++ E +++
Sbjct: 1120 LEEELEAERTARA-KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRR 1178
Query: 384 RLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
LEE +E T LR K + + + ++D + K L +E + +L D +N+
Sbjct: 1179 DLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Score = 53.2 bits (122), Expect = 2e-06
Identities = 81/413 (19%), Positives = 164/413 (39%), Gaps = 41/413 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE ++ ++ LE E+++R +ER K L + E + + E E +K++
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEF 1087
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + +ED + + + L K+NQ + + +E+++ +A+ EK +S E+
Sbjct: 1088 DINQQNSKIEDEQVLALQLQKKL-KENQARIEELEEELEAERTARAKVEKLRSDLSRELE 1146
Query: 155 ELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK----IEELN 192
E+ ++E T +I ++K E + E T + L K + EL
Sbjct: 1147 EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELG 1206
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXX 252
I ++ KQ+L +E E E+ D+ N+E ++ K+ +
Sbjct: 1207 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLE 1266
Query: 253 XXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
SL+ D + R +L+ E+ +L RQL + I S+
Sbjct: 1267 EAQRSLN----DFTTQRAKLQTENG---ELSRQLEEKEALI----SQLTRGKLSYTQQME 1315
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEV---LIIDLEKANGTARELQK 369
+ L + ++ + + + + E E L L KAN + +
Sbjct: 1316 DLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRT 1375
Query: 370 R--TEQLERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ T+ ++R E K +L + +Q E+ + K + L++ H L E
Sbjct: 1376 KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIE 1428
Score = 46.8 bits (106), Expect = 2e-04
Identities = 39/191 (20%), Positives = 85/191 (44%), Gaps = 6/191 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+E + L+Q +LE R + ++ ER + ++I+ SER++ S +K D +
Sbjct: 1676 VERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDAD 1735
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +L+ +E+ E KK + E++ + T A E+ K + + +
Sbjct: 1736 LSQLQSEVEEAVQECRNAEEKAKKAITHAAM-MAEELKKEQDTSAHLERMKKNMEQTIKD 1794
Query: 156 LLAQVENVTKEKITI---SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
L +++ E+I + K ++LE + EL ++E + + ++ + EL
Sbjct: 1795 LQHRLDEA--EQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKEL 1852
Query: 213 VKEVQDLKVNI 223
+ ++ K N+
Sbjct: 1853 TYQTEEDKKNL 1863
Score = 45.2 bits (102), Expect = 6e-04
Identities = 62/411 (15%), Positives = 156/411 (37%), Gaps = 13/411 (3%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESE-RELRQRIEREKADL---SVQVIQLSERLEEAEG 80
E ++ L ++ ++ + + +L+S E +E E+ + ++ Q+ +E
Sbjct: 1520 EGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1579
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + E ++ ++ + D S +KKK + + + + Q+ + A
Sbjct: 1580 EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAA 1639
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
A+K+ Q+ + + Q+++ + + + +E + L ++EEL R +V+ T
Sbjct: 1640 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEEL-RAVVEQTE 1698
Query: 201 HKQRLS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
++L+ +E IE + VQ L +++ K ++ +
Sbjct: 1699 RSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAK 1758
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ + +L++E + LER I + + K
Sbjct: 1759 KAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLE 1818
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
+ N E K +SE + + + + L + + ++++ +
Sbjct: 1819 ARVRELEGELEA--EQKRNAESVKGMRKSERRIKELTYQ-TEEDKKNLLRLQDLVDKLQL 1875
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++K+ + + EQ +L ++ ++V HELD+ E+ D + K+
Sbjct: 1876 KVKAYKRQAEEAEEQANTNL----SKFRKVQHELDEAEERADIAESQVNKL 1922
Score = 39.5 bits (88), Expect = 0.028
Identities = 65/347 (18%), Positives = 135/347 (38%), Gaps = 29/347 (8%)
Query: 116 LLKK-KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN----VTKEKITI 170
LLK + ++ + +E+ ++ +T ++E + + + ++ LL + + V E+ +
Sbjct: 841 LLKSAETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNL 900
Query: 171 SKTCERLEITIS---ELHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLK 220
+ ER + I +L K++E+N + D +T+ K++L E EL K++ DL+
Sbjct: 901 NDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLE 960
Query: 221 VNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI-DLESVRVQLE 273
+ + V K + ++ HQ + DL++ ++
Sbjct: 961 LTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVN 1020
Query: 274 EESEARLDLERQLVKANGEIGH---WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
S++++ LE+Q+ G + R
Sbjct: 1021 TLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEE 1080
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
L K ++ +Q S+++ E +VL + L+K +E Q R E+LE ++ + +
Sbjct: 1081 KLKKKEFDINQQNSKIEDE-QVLALQLQK---KLKENQARIEELEEELEAERTARAKVEK 1136
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
L R+L L+ E E +KM DL +A
Sbjct: 1137 LRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 241 bits (591), Expect = 3e-63
Identities = 135/462 (29%), Positives = 232/462 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1112 IKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKR 1171
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK+ + V + +QID L + K + EKEKS+ + E
Sbjct: 1172 EAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKME 1231
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ +L + +E V+K K K C LE +SE+ K EE R I ++++ K RL E+ E
Sbjct: 1232 INDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEF 1291
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + K Q +L D + +R Q
Sbjct: 1292 SRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY 1351
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE EA+ +L+R + KAN E+ WR+K+ K + +
Sbjct: 1352 EEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAV 1411
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+K ++EK K RLQ+EVE L+ID+E++N L K+ ++V E K + EET
Sbjct: 1412 NSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAEL 1471
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL +V + +++ + + L RENK + ++ D I
Sbjct: 1472 EASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELE 1531
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +EAEA + EE + R+ E Q +
Sbjct: 1532 KVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVK 1573
Score = 84.2 bits (199), Expect = 1e-15
Identities = 73/402 (18%), Positives = 168/402 (41%), Gaps = 8/402 (1%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA 82
+++ A +AL + D + + ++S + ++Q++E+EK++L +++ L+ +E A
Sbjct: 1187 LQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSK-A 1245
Query: 83 ESQFE-INRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
++ FE + R + +L +++ K E L +E +A + + +F Q+D+ +
Sbjct: 1246 KANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG--EFSRQLDEKDAMVS 1303
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ + K F ++ EL Q+E TK K T++ + L + EE ++
Sbjct: 1304 QLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQR 1363
Query: 201 HKQRLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
+ + E + K D E + K ++A + +
Sbjct: 1364 GMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQ 1423
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+++ ++E + + +E + A + L+++ + + W+ K+ S
Sbjct: 1424 RLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRS-LS 1482
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
+ + ++++ LQ E+ L + + EL+K +QL+
Sbjct: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKS 1542
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKD 1584
Score = 70.9 bits (166), Expect = 1e-11
Identities = 91/488 (18%), Positives = 179/488 (36%), Gaps = 31/488 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ +++ D L E ++ + K L ++ +++ER E+ E RK + E
Sbjct: 891 LQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE 950
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+L+K ++D+ L + K + V + E++ L +T A+ KEK Q +
Sbjct: 951 CSELKKDIDDLELTLAKVEKE-KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQ 1009
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ------RLSQEN 209
L ++ + T++K +LE + +L +E+ + +D+ K+ +L+QE+
Sbjct: 1010 TLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQES 1069
Query: 210 -IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
++ + Q L ++ + S + + A + ++E ++E+
Sbjct: 1070 TMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAE 1129
Query: 269 RVQLEEESEARLDLERQL---------------------VKANGEIGHWRSKFXXXXXXX 307
R + + R DL R+L K E R
Sbjct: 1130 RASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQH 1189
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K++ +L +EK+KS L+ E+ L ++E +
Sbjct: 1190 EATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANF 1249
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+K LE EIK++ EE +L + TE S +LD+ L+R
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGK 1309
Query: 428 KKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRL 486
+ + + + + Y+E E KAE QR +
Sbjct: 1310 QAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE-EQEAKAELQRGMSKA 1368
Query: 487 TAEFGQFR 494
+E Q+R
Sbjct: 1369 NSEVAQWR 1376
Score = 60.5 bits (140), Expect = 1e-08
Identities = 58/225 (25%), Positives = 107/225 (47%), Gaps = 29/225 (12%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A ++LE ++ ++ LE E++L +ER K L + E + E + E +K
Sbjct: 1027 AKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKK 1086
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSK 148
++ E+ L+ +ED + A L+KK +E+ + + +E+I+ ++A+AEK++S
Sbjct: 1087 KEFEMSNLQGKIED----EQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD 1142
Query: 149 FQAEVYELLAQVE---NVTKEKITISKTCE---------------RLEITISELHIK--- 187
E+ E+ ++E T +I ++K E + E T + L K
Sbjct: 1143 LSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHAD 1202
Query: 188 -IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
+ EL + I + KQ+L +E EL E+ DL N+E V K+
Sbjct: 1203 SVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKA 1247
Score = 53.2 bits (122), Expect = 2e-06
Identities = 68/388 (17%), Positives = 158/388 (40%), Gaps = 15/388 (3%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-VHLESEETAHLL 117
+EK DL +QV ++ L +AE + + + + ++ ++ + ED + +E TA
Sbjct: 886 QEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAK-- 943
Query: 118 KKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV--TKEKITISKTC- 174
K+K ++ + ++ ID L T A+ EKEK + +V L ++ + T K+T K
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 175 -ERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
E + T+ +L ++ +++N +T K +L Q+ +L ++ K ++ K ++
Sbjct: 1004 QEAHQQTLDDLQMEEDKVN----TLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
L + E ++ +++ ++E+E + L++++ + I
Sbjct: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARI 1119
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
+ A +E K R ++E + +
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKR-EAEFQKM 1178
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
DLE+ + + + L + + + + L + + ++ ++ L +++EL+ ++L
Sbjct: 1179 RRDLEE---STLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDL 1235
Query: 414 DKTREQKDALARENKKMGDDLHDARANI 441
E +KM L D + I
Sbjct: 1236 ASNMETVSKAKANFEKMCRTLEDQLSEI 1263
Score = 50.4 bits (115), Expect = 1e-05
Identities = 48/260 (18%), Positives = 111/260 (42%), Gaps = 8/260 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E R +R ER + +++ SER++ S +K
Sbjct: 1675 LAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKL 1734
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T++ +++ +ED+ E+ KK + + E++ + T A E+ K +
Sbjct: 1735 ETDISQIQGEMEDIVQEARNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNMEQT 1793
Query: 153 VYELLAQVENVTKEKITI---SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
V +L Q+ E++ + K ++LE + EL ++E + V+ ++ +
Sbjct: 1794 VKDL--QLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRV 1851
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV- 268
EL + ++ + NI + L ++ ++ A +++ +LE
Sbjct: 1852 KELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAE 1911
Query: 269 -RVQLEEESEARLDLERQLV 287
R + E +L ++ + V
Sbjct: 1912 ERADIAESQVNKLRVKSREV 1931
Score = 46.4 bits (105), Expect = 2e-04
Identities = 76/355 (21%), Positives = 137/355 (38%), Gaps = 37/355 (10%)
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF---QAEVYELLAQVENVT 164
L+S ET + +E F++ ++L KT+A+ ++ + K E +L QV+
Sbjct: 844 LKSAETEKEMANMKEE----FEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEA 899
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQ 217
+ C++L T +L KI+E+ D +T+ K++L E EL K++
Sbjct: 900 DALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
Query: 218 DLKVNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI-DLESVRV 270
DL++ + V K + ++ HQ + DL+
Sbjct: 960 DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEED 1019
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
++ ++A+ LE+Q+ G + K
Sbjct: 1020 KVNTLTKAKTKLEQQVDDLEGSL-EQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQ 1078
Query: 331 TLIAKINNVEKQKSRLQSEVE---VLIIDLEKANGTARELQKRTEQL-ERVNIEIKSRLE 386
L K+ E + S LQ ++E L + L+K +ELQ R E+L E + E SR +
Sbjct: 1079 QLNEKLKKKEFEMSNLQGKIEDEQALAMQLQK---KIKELQARIEELEEEIEAERASRAK 1135
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ + DL EL+ +S L++ A NKK + R ++
Sbjct: 1136 A-----EKQRSDL---SRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDL 1182
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 241 bits (591), Expect = 3e-63
Identities = 134/462 (29%), Positives = 230/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I +++++E+E LR +IE++++DL+ ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1112 IKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKR 1171
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E K+R+ LE+ L+ E TA L+KK + V + EQID L + K + EKEKS+ + E
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKME 1231
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++ + +E ++K K I +TC +E SE+ K E+ + I D+ K RL +N EL
Sbjct: 1232 IDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGEL 1291
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
V++ + I + K + Q +L D + +R Q
Sbjct: 1292 SHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQY 1351
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE EA+ +L+R L KAN E+ W++K+ K + T
Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETA 1411
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+K ++EK K RLQ EVE L+ DLE+++ L K+ ++V E K +L+E+
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E Q++ R+ TEL ++ + ++ +Q + L RENK + +++ D I
Sbjct: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +E E + EE + R+ E Q +
Sbjct: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVK 1573
Score = 66.5 bits (155), Expect = 2e-10
Identities = 65/414 (15%), Positives = 164/414 (39%), Gaps = 10/414 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A + L + + D + + + +++ + ++Q++E+EK++L +++ ++ +E A
Sbjct: 1184 EATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIE-AL 1242
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
++S E + + K ++ + ++ K + Q + ++++
Sbjct: 1243 SKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLI 1302
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
++ K K ++ EL Q+E TK K ++ + L + EE ++
Sbjct: 1303 SQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAEL- 1361
Query: 200 SHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ LS+ N E+ K D E + K ++A +
Sbjct: 1362 --QRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLE 1419
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+ +++ ++E + LE A L+++ + + W+ K
Sbjct: 1420 KTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESR 1479
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
S ++ ++ + ++ LQ E+ L + + +E +K + +E
Sbjct: 1480 S-LSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVE 1538
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ +++ LEE E + + Q EL +V ELD+ +KD + K+
Sbjct: 1539 QEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKR 1592
Score = 64.9 bits (151), Expect = 6e-10
Identities = 94/498 (18%), Positives = 195/498 (39%), Gaps = 36/498 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIE---REKADLSVQVIQLSERLEEAEGGAESQF 86
+S L D +Q + E+ + +R E + K L +V +L+ERLEE E
Sbjct: 882 VSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELV 941
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R + + L++ ++D+ L + K + V + E++ L + ++ KEK
Sbjct: 942 AKKRNLEDKCSSLKRDIDDLELTLTK-VEKEKHATENKVKNLSEEMTALEENISKLTKEK 1000
Query: 147 SKFQAEVYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
Q + L ++ V ++K+ + K +LE +L +E+ + D+ K++L
Sbjct: 1001 KSLQEAHQQTLDDLQ-VEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL 1059
Query: 206 ------SQENI-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
SQE+I +L E Q ++ ++ + SQ+ ++ A +
Sbjct: 1060 EGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARI 1119
Query: 259 HQVEIDLE---SVRVQLEEE-SEARLDLE---RQLVKANG--------------EIGHWR 297
++E ++E ++R ++E++ S+ +LE +L +A+G E R
Sbjct: 1120 EELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMR 1179
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
K + L +EK+KS L+ E++ + ++
Sbjct: 1180 RDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNI 1239
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
E + + +++ +E EIK++ E+ QL QT+ +SH +++
Sbjct: 1240 EALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKE 1299
Query: 418 EQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK 477
L + + + L + + + Y+E E K
Sbjct: 1300 SLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEE-EQEAK 1358
Query: 478 AEEQRS-QRLTAEFGQFR 494
AE QR+ + +E Q++
Sbjct: 1359 AELQRALSKANSEVAQWK 1376
Score = 61.7 bits (143), Expect = 6e-09
Identities = 72/419 (17%), Positives = 167/419 (39%), Gaps = 28/419 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+S L ++I +L+ + ++ +E+EK+DL V LEE EG E + +
Sbjct: 1513 ISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA-------LEEVEGSLEHEESKILRV 1565
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
EL +++ L+ +E +E LK+ +Q Q +D +++ A + K K + +
Sbjct: 1566 QLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD 1625
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ E+ Q+ + ++ + ++ + + + +++ R+ D+ + + N L
Sbjct: 1626 LNEMEIQLGHSNRQMAETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLL 1685
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
++E++++KV +E + + + ++E D+ + ++
Sbjct: 1686 LEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
E + + E + KA + +
Sbjct: 1746 ENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1805
Query: 333 IAKINNVEKQKSRLQSEVEVL--IIDLEKANGT---------ARELQKRTEQLE--RVNI 379
+ +KQ +L++ V L +D+E+ G R++++ T Q E R NI
Sbjct: 1806 QLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDRKNI 1865
Query: 380 ----EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + + + +RV HEL++ E+ D + K+
Sbjct: 1866 LRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKL 1924
Score = 60.9 bits (141), Expect = 1e-08
Identities = 96/441 (21%), Positives = 174/441 (39%), Gaps = 44/441 (9%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
++LE + ++ LE E++LR +ER K L + E + + E + E +K++
Sbjct: 1029 AKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKE 1088
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
EL +L+ ++D + S + +K+ Q + + +E+I+ +A+ EK++S E+
Sbjct: 1089 FELSQLQARIDDEQVHSLQFQKKIKEL-QARIEELEEEIEAEHTLRAKIEKQRSDLAREL 1147
Query: 154 YEL---LAQVENVTKEKITISKTCE---------------RLEITISELHIK----IEEL 191
E+ L + T +I ++K E + E T + L K + EL
Sbjct: 1148 EEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAEL 1207
Query: 192 NRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIA----------SQXXXXX 241
I ++ KQ+L +E EL E+ D+ NIE + KS I S+
Sbjct: 1208 GEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKD 1267
Query: 242 XXXXXXXXXXXXXXASL--------HQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
A L H+VE + ES+ QL + +A +L + E
Sbjct: 1268 EQQTQLIHDLNMQKARLQTQNGELSHRVE-EKESLISQLTKSKQALTQQLEELKRQMEEE 1326
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ +Y L + V + K++ +++
Sbjct: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQR 1386
Query: 354 IIDLEKA-NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHE 412
+LE+A A+ LQ+ E+ E N + S LE+T Q + DL
Sbjct: 1387 TEELEEAKKKLAQRLQEAEEKTETANSKCAS-LEKTKQRLQGEVEDLMRDLERSHTACAT 1445
Query: 413 LDKTREQKDALARENKKMGDD 433
LDK + D + E K+ D+
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDE 1466
Score = 57.2 bits (132), Expect = 1e-07
Identities = 64/402 (15%), Positives = 150/402 (37%), Gaps = 4/402 (0%)
Query: 42 LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
L+++ E E+E + ++R + + +V Q + E + E +K+ + +L++
Sbjct: 1346 LLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQ--RLQE 1403
Query: 102 LLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
E + + A L K K Q V D +++ A +K++ F + E +
Sbjct: 1404 AEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQK 1463
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
++ E K L + ++ EE+ + + + L +E +L +++ +
Sbjct: 1464 LDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAET 1523
Query: 220 KVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR 279
N++ K + + + + +V+++L V+ +L+ + +
Sbjct: 1524 GKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEK 1583
Query: 280 LDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNV 339
+ QL + + K ++
Sbjct: 1584 DEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
++ +Q +++ + L+ A + +L+++ +ER N + LEE EQT+R
Sbjct: 1644 QRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTR 1703
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
R + EL S + Q +L KK+ D+ +A +
Sbjct: 1704 RLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEV 1745
Score = 53.6 bits (123), Expect = 2e-06
Identities = 81/429 (18%), Positives = 187/429 (43%), Gaps = 36/429 (8%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDL----ESERELRQRIEREKADLSVQ------VI 69
T V E A + + L +++ +++++ + ++ L++ ++ DL V+ +I
Sbjct: 966 TKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLI 1025
Query: 70 QLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQ 129
+++ +LE+ E E +K +L + ++ LE S+E+ L+ + Q+I +
Sbjct: 1026 KINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLK 1085
Query: 130 EQIDQLTKTKARAEKEK---SKFQAEVYELLAQVENVTKEKITISKTCE-RLEITISELH 185
++ +L++ +AR + E+ +FQ ++ EL A++E + +E+I T ++E S+L
Sbjct: 1086 KKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEEL-EEEIEAEHTLRAKIEKQRSDLA 1144
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXX 245
++EE++ + + + + N + E Q ++ ++E A+
Sbjct: 1145 RELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA---------- 1194
Query: 246 XXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXX 305
A L + +L+ V+ +LE+E ++ L +E + +N E +SK
Sbjct: 1195 TLRKKQADSVAELGEQIDNLQRVKQKLEKE-KSELKMEIDDMASNIE-ALSKSKSNIERT 1252
Query: 306 XXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
K I+++ QK+RLQ++ L +E+
Sbjct: 1253 CRTVEDQFSEIKAKDEQQTQL---------IHDLNMQKARLQTQNGELSHRVEEKESLIS 1303
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L K + L + E+K ++EE + L++ + + + + ++ +E K L R
Sbjct: 1304 QLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQR 1363
Query: 426 ENKKMGDDL 434
K ++
Sbjct: 1364 ALSKANSEV 1372
Score = 39.5 bits (88), Expect = 0.028
Identities = 49/324 (15%), Positives = 121/324 (37%), Gaps = 9/324 (2%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISE 183
DF+ ++L +++AR ++ + K + E +L QV++ T+ + + CE L +
Sbjct: 859 DFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIL 918
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L K++EL + + L + L + LK +I+++ +++ +
Sbjct: 919 LEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENK 978
Query: 244 XXXXXXXXXXXXASLHQV---EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKF 300
++ ++ + L+ Q ++ + D L+K N ++
Sbjct: 979 VKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDL 1038
Query: 301 XXX---XXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
K L + +E++ + + E+ L +
Sbjct: 1039 EGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARI 1098
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ + + QK+ ++L+ E++ +E L + ++ + EL+ +S L++
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEAS 1158
Query: 418 EQKDALARENKKMGDDLHDARANI 441
A NKK + R ++
Sbjct: 1159 GATSAQIEMNKKREAEFQKMRRDL 1182
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 238 bits (582), Expect = 4e-62
Identities = 138/462 (29%), Positives = 228/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I + +++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1111 IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKR 1170
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E KLR+ LE+ L+ E L+KK+ + + + EQID L + K + EKEKS+ + E
Sbjct: 1171 EAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME 1230
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+L + E ++K K + K C LE +SEL K EE R I D+T+ + RL E E
Sbjct: 1231 TDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEY 1290
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + K Q +L D + +R Q
Sbjct: 1291 SRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQY 1350
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 1351 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAV 1410
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L++D+E++N L K+ ++V E K + EET
Sbjct: 1411 NAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL 1470
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL +V + +++ +Q + L RENK + ++ D I
Sbjct: 1471 EASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELE 1530
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1531 KIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
Score = 75.8 bits (178), Expect = 3e-13
Identities = 72/407 (17%), Positives = 169/407 (41%), Gaps = 12/407 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++AL + D + + + +++ + ++Q++E+EK++L ++ LS E
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAIS 1242
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ ++ R + ++ +L+ K E L ++ TA + + Q ++ Q+D+
Sbjct: 1243 KAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQ--RARLQTEAGEYSRQLDEKDAL 1300
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K ++ EL Q+E TK K ++ + L + EE ++
Sbjct: 1301 VSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL 1360
Query: 199 TSHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ LS+ N E+ K D E + K ++A +
Sbjct: 1361 ---QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASL 1417
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ +++ ++E + + +E + A L+++ + + W+ K+
Sbjct: 1418 EKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 1477
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
S + ++ + ++ LQ E+ L + + EL+K +Q+
Sbjct: 1478 RS-LSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+ EI++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1537 EQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1583
Score = 62.1 bits (144), Expect = 5e-09
Identities = 71/460 (15%), Positives = 171/460 (37%), Gaps = 4/460 (0%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A ++LE ++ ++ LE E++LR +ER K L + E + E + E K
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK 1085
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
++ E+ L +ED + +K+ Q + + E+I+ ++A+AEK++S
Sbjct: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKEL-QARIEELGEEIEAERASRAKAEKQRSDLSR 1144
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRLSQENI 210
E+ E+ ++E + ++ E +L +EE + + + +++ +
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL +++ +L+ + + KS++ + +E + ++
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKT 1264
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
+ EE+ DL Q + E G + +
Sbjct: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE-ETV 389
AK N + + + ++L E+ ELQ+ + + +++ E + +
Sbjct: 1325 ETKAK-NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1383
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXX 449
Q E+ + + LQ ++ + +L + +++ +++ D ++
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
Query: 450 XXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
Y+E +A +A ++ S+ L+ E
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Score = 60.1 bits (139), Expect = 2e-08
Identities = 76/413 (18%), Positives = 162/413 (39%), Gaps = 16/413 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ + +D+L R+ +E +EK DL +QV ++ L +AE E
Sbjct: 852 MATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQL 911
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAE 143
I K E K++++ E E E A L KK ++ + ++ ID L T A+ E
Sbjct: 912 --IKNKIQLEA-KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
KEK + +V L ++ + + +SK + L+ T + ++ + +T K
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+L Q+ +L ++ K ++ K ++ L + E
Sbjct: 1029 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF 1088
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
++ ++ ++E+E + L++++ + I +
Sbjct: 1089 EISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A VE K R ++E + L DLE+A + + L + + + +
Sbjct: 1149 ISERLEEAGGATSAQVELNKKR-EAEFQKLRRDLEEA---TLQHEAMVAALRKKHADSMA 1204
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
L E + ++ ++ L +++EL+ + +L E +KM L D
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLED 1257
Score = 56.0 bits (129), Expect = 3e-07
Identities = 82/441 (18%), Positives = 168/441 (38%), Gaps = 36/441 (8%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
++ ++E+ ++++ +++ L ++ + D + Q E E EG AE Q ++
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE---EQEGKAELQRALS- 1365
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
K ++E+ + R E ++ E KKK + + + +E ++ + A EK K + Q
Sbjct: 1366 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 1425
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
EV +L+ VE + K + +SE K EE + + LS E
Sbjct: 1426 NEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELF 1485
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
++ ++ +E + + + QVE + ++
Sbjct: 1486 KVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA 1545
Query: 271 QLEEESEARLDLER-QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
LEE +EA L+ E ++++ E+ +S+ ++
Sbjct: 1546 ALEE-AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTL 1604
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE----------LQKRT-------- 371
I N+ + K +++ ++ + I L AN A E + K T
Sbjct: 1605 DAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDAL 1664
Query: 372 -------EQL----ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
EQL R N+ +++ +EE EQT+R + + EL S + Q
Sbjct: 1665 RGQEDLKEQLAIVERRANL-LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQN 1723
Query: 421 DALARENKKMGDDLHDARANI 441
+L KK+ +D+ ++ +
Sbjct: 1724 TSLINTKKKLENDVSQLQSEV 1744
Score = 54.0 bits (124), Expect = 1e-06
Identities = 88/433 (20%), Positives = 182/433 (42%), Gaps = 46/433 (10%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE +
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 1469
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL K++ + E+ L+ ET L+++N+ + Q++I LT+ A
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEE-SLDQLET---LRRENKNL----QQEISDLTEQIAE 1521
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE-----LHIKIE------E 190
K+ ++EL + V +EK I E E ++ L I++E E
Sbjct: 1522 GGKQ-------IHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE 1574
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXX 246
++R I + +L + + +V+ +Q D ++ N + +K ++
Sbjct: 1575 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1634
Query: 247 XXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGH-WRS 298
+ + L+ ++ L++ + DL+ QL +AN EI W +
Sbjct: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL- 357
S +LI +E S+LQSEVE +I +
Sbjct: 1695 --LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
Query: 358 ---EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
EKA + E+L++ + + LE + EQT +DL+++ E ++++ +
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1811
Query: 415 KTREQK-DALARE 426
K + QK +A RE
Sbjct: 1812 KKQIQKLEARVRE 1824
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/192 (18%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E ++ ER + +++ SER++ S +K
Sbjct: 1674 LAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1733
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ ++ +L+ +E+V ES KK + + E++ + T A E+ K +
Sbjct: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1792
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + + ++ + E
Sbjct: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1852
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 1853 LTYQTEEDRKNV 1864
>BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein.
Length = 1006
Score = 235 bits (576), Expect = 2e-61
Identities = 140/462 (30%), Positives = 230/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ + ++++LE+ER R R+E+++A+ + ++ +LSERLEEA G + Q E RKR
Sbjct: 180 IKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKR 239
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ EL +LR+ LE+ L E T L++K E + EQ+D L + + + EKEKS+ + E
Sbjct: 240 EAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRME 299
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
V +L A VE +T+ K + K C E +SE IK+EEL R + D ++ + RL E+ EL
Sbjct: 300 VDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL 359
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+ +++ + I + K+ A ++ + D + +R Q
Sbjct: 360 SRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQH 419
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WRSK+ K +
Sbjct: 420 EEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAA 479
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E E + ++LE+A A L K+ LER E + + EE +
Sbjct: 480 NAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQREL 539
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E QR+ R TEL R+ H ++ E + L RENK + +++ D ++
Sbjct: 540 EAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE 599
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAE + EE ++ R+ E Q +
Sbjct: 600 KTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 641
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/402 (17%), Positives = 154/402 (38%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + D + + Q +E+ K L + ++ LEEAEG E + + E
Sbjct: 577 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 636
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +++ ++ E +E L++ +Q V Q +D T+ + A + K K + ++ +
Sbjct: 637 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 696
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L Q+ + T++ ++ + E +E R ++ Q L + L E
Sbjct: 697 LELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 756
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + ++E DL + ++EE
Sbjct: 757 LEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEA 816
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
++ R + E + KA + + A
Sbjct: 817 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 876
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
+ +KQ +L+++V L +L+ E K + ER E+ + EE + +
Sbjct: 877 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARM 936
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
Q + Q++++ + ++ +Q + + +K +L DA
Sbjct: 937 QDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDA 978
Score = 72.5 bits (170), Expect = 3e-12
Identities = 89/478 (18%), Positives = 183/478 (38%), Gaps = 18/478 (3%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
SA A RLE ++ ++ LE E++LR ER K L + E + +A +
Sbjct: 90 SALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLE 149
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E +K+D+EL +L +ED L + +K+ Q + +E+++ +AR EK++
Sbjct: 150 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL-QARAEELEEELEAERAARARVEKQR 208
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRL 205
++ E+ EL ++E + C + E + L ++EE R + + +++
Sbjct: 209 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 268
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
++ EL ++V L+ + + KS++ + E L
Sbjct: 269 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 328
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++++EE L+RQL A+ + G +++ + S
Sbjct: 329 SEAKIKVEE-------LQRQLADASTQRGRLQTE-SGELSRLLEEKECLISQLSRGKALA 380
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIID---LEKANGTARELQKRTEQ-LERVNIEI 381
L ++ K KS L V+ L D L + + E Q ++ L + N E+
Sbjct: 381 AQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEV 440
Query: 382 ---KSRLE-ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+S+ E + +Q E+ + + LQ ++ + +L + ++ + D
Sbjct: 441 AQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDV 500
Query: 438 RANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
+ +E + +A ++ S+ L E + RH
Sbjct: 501 TLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 558
Score = 58.4 bits (135), Expect = 6e-08
Identities = 77/362 (21%), Positives = 139/362 (38%), Gaps = 33/362 (9%)
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
RK + E +L+K ++D+ L + A K+ + V + E++ L ++ AR KEK
Sbjct: 13 RKLEDECTELKKDIDDLELTLAK-AEKEKQATENKVKNLTEEMAALDESVARLTKEKKAL 71
Query: 150 QAEVYELLA-------QVENVTKEKITISKTCERLEITISE---LHIKIEELNR------ 193
Q + L +V +TK K+ + + E LE ++ + L + E R
Sbjct: 72 QEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDL 131
Query: 194 -----TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
++ D KQ+L ++ + E+ L + +E+ L +Q+ +
Sbjct: 132 KLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELE 191
Query: 249 XXXXXXXASLHQVE-------IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
A+ +VE +LE + +LEE A K E+G R +
Sbjct: 192 EELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELE 251
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN 361
K + +L +EK+KS L+ EV+ L ++E
Sbjct: 252 EAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLT 311
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+K E E K ++EE ++ D ++ LQ S EL + E+K+
Sbjct: 312 RAKASAEKLCRTYEDQLSEAKIKVEE----LQRQLADASTQRGRLQTESGELSRLLEEKE 367
Query: 422 AL 423
L
Sbjct: 368 CL 369
Score = 52.0 bits (119), Expect = 5e-06
Identities = 69/339 (20%), Positives = 138/339 (40%), Gaps = 38/339 (11%)
Query: 109 ESEETAHLL--KKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
E E A L ++K ++ + ++ ID L T A+AEKEK + +V+N+T+E
Sbjct: 1 EGEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATE-------NKVKNLTEE 53
Query: 167 KITISKTCERLEITISELHIKIEELNRTIVDITSHKQR---LSQENIELVKEVQDLKVNI 223
+ ++ RL E E + + D+ + + R L++ + L ++V+DL+ ++
Sbjct: 54 MAALDESVARL---TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSL 110
Query: 224 ENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLE 283
E L+ + ++E DL+ + + + ++ + LE
Sbjct: 111 EQEKKLRMD---------------------TERAKRKLEGDLKLTQESVADAAQDKQQLE 149
Query: 284 RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQK 343
+L K + E+ + + A+ VEKQ+
Sbjct: 150 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARA-RVEKQR 208
Query: 344 SRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQ 403
+ E+E L LE+A G + ++ + E ++ LEE +E T LR KQ
Sbjct: 209 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 268
Query: 404 TE-LQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + ++D + + L +E ++ ++ D AN+
Sbjct: 269 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV 307
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/418 (19%), Positives = 160/418 (38%), Gaps = 16/418 (3%)
Query: 18 GTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE 77
G N + S+ A RL+ + + +LE +++++ L + + + EE
Sbjct: 475 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 534
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E+ +R TEL +LR E+ LE+ ET K QE + D +Q+ K
Sbjct: 535 MQRELEAAQRESRGLGTELFRLRHGHEEA-LEALETLKRENKNLQEEISDLTDQVSLSGK 593
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV 196
+ EK K + E E+ A +E ++ +KT R+++ +S++ +++
Sbjct: 594 SIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTL-RIQLELSQVKAEVDRKLAEKD 652
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ ++ +R Q +E ++ D + N + LK ++
Sbjct: 653 EECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQ 712
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A+ ++ QL+EE R D E++L E +
Sbjct: 713 AATRLMQ-------AQLKEEQAGR-DEEQRLAAELHEQAQALERRASLLAAELEELRAAL 764
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE-LQKRTEQL 374
+ ++N + Q + L ++ + L DL + +G E Q+R E
Sbjct: 765 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 824
Query: 375 ERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD-KTREQKDALARENKK 429
E+ I + + E ++ + T L + L++ EL + E + A R KK
Sbjct: 825 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKK 882
Score = 50.8 bits (116), Expect = 1e-05
Identities = 96/499 (19%), Positives = 197/499 (39%), Gaps = 48/499 (9%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA 82
+ + A ++AL R + + + + ++S + +RQ++E+EK++L ++V L+ +E
Sbjct: 255 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 314
Query: 83 ESQFEINRKRDTELLK-------LRKLLED-------VHLESEETAHLLKKKN------- 121
S ++ R + +L + L++ L D + ES E + LL++K
Sbjct: 315 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 374
Query: 122 ------QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
+ + + + Q+++ +K K+ + + L Q E + + + +
Sbjct: 375 RGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLS 434
Query: 176 RLEITISELHIKIEE--LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+ +++ K E + RT ++ K++L+ E + V+ ++ K ++
Sbjct: 435 KANAEVAQWRSKYEADAIQRT-EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRL 493
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
++ +E LE R Q EEE + L+ ++ + G
Sbjct: 494 QTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ-EEEMQRELEAAQRESRGLGT- 551
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK-INNVEKQKSRLQSEVEV 352
+R + K +L K I +EK K L+ E
Sbjct: 552 ELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSE 611
Query: 353 LIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR-NKQTELQRVSH 411
+ LE+A G + +T +++ ++K+ ++ + ++ +LR N Q ++ +
Sbjct: 612 IQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQA 671
Query: 412 ELD-KTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYK 470
LD +TR + +AL R KKM DL+D + A K
Sbjct: 672 SLDAETRARNEAL-RLKKKMEGDLNDLELQL-------GHATRQATEAQAATRLMQAQLK 723
Query: 471 EAEAGRKAEEQRSQRLTAE 489
E +AGR E QRL AE
Sbjct: 724 EEQAGRDEE----QRLAAE 738
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER-- 74
G D+ ++ + + RL+Q L+ E+ R +R A+L Q L R
Sbjct: 692 GDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRAS 751
Query: 75 -----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDF 128
LEE E R + ELL+ + L +H S+ T L +KK E +
Sbjct: 752 LLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH--SQNTGLLNQKKKLEADLAQL 809
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
++++ + + AE++ K + + +++ + + + LE T+ EL ++
Sbjct: 810 SGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARL 869
Query: 189 EE 190
EE
Sbjct: 870 EE 871
Score = 41.5 bits (93), Expect = 0.007
Identities = 80/381 (20%), Positives = 142/381 (37%), Gaps = 27/381 (7%)
Query: 46 DLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
DL++E + + + K L QV L LE+ + RK + +L ++ + D
Sbjct: 81 DLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVAD 140
Query: 106 VHLESEETAHLLKKKNQEI-VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
+ ++ LKKK+ E+ + + + +QL A+ +K+ + QA EL ++E
Sbjct: 141 AAQDKQQLEEKLKKKDSELSQLSLRVEDEQL--LGAQMQKKIKELQARAEELEEELEAER 198
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ + K + EL ++EE ++ E L +E+++ + E
Sbjct: 199 AARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHE 258
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE-EESEARLDLE 283
V A L + L+ VR +LE E+SE R++++
Sbjct: 259 ATV-----------------AALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVD 301
Query: 284 RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS-XXXXXXXXXXXTLIAKINNVEKQ 342
+ AN E R+K K T ++ +
Sbjct: 302 D--LAANVET-LTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGE 358
Query: 343 KSRLQSEVEVLIIDLEKANG-TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
SRL E E LI L + A+ L++ QLE + + KS L VQ LR
Sbjct: 359 LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEES-KAKSALAHAVQALRHDCDLLRE 417
Query: 402 KQTELQRVSHELDKTREQKDA 422
+ E EL + + +A
Sbjct: 418 QHEEEAEAQAELQRLLSKANA 438
Score = 31.9 bits (69), Expect = 5.5
Identities = 25/160 (15%), Positives = 62/160 (38%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+++ + K K RL+ +VE L LE+ + ++ +LE + + + Q +Q
Sbjct: 88 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 147
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXX 454
+ L+ K +EL ++S ++ + + ++ K++ + +
Sbjct: 148 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 207
Query: 455 XXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +EA + + ++ AE G+ R
Sbjct: 208 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 247
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 235 bits (576), Expect = 2e-61
Identities = 140/462 (30%), Positives = 230/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ + ++++LE+ER R R+E+++A+ + ++ +LSERLEEA G + Q E RKR
Sbjct: 1157 IKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKR 1216
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ EL +LR+ LE+ L E T L++K E + EQ+D L + + + EKEKS+ + E
Sbjct: 1217 EAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRME 1276
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
V +L A VE +T+ K + K C E +SE IK+EEL R + D ++ + RL E+ EL
Sbjct: 1277 VDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL 1336
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+ +++ + I + K+ A ++ + D + +R Q
Sbjct: 1337 SRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQH 1396
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WRSK+ K +
Sbjct: 1397 EEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAA 1456
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E E + ++LE+A A L K+ LER E + + EE +
Sbjct: 1457 NAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQREL 1516
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E QR+ R TEL R+ H ++ E + L RENK + +++ D ++
Sbjct: 1517 EAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE 1576
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAE + EE ++ R+ E Q +
Sbjct: 1577 KTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618
Score = 74.1 bits (174), Expect = 1e-12
Identities = 91/408 (22%), Positives = 159/408 (38%), Gaps = 33/408 (8%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
QD+L E + + K L +V +LSERLE+ E RK + E +L+K +
Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA----- 158
+D+ L + A K+ + V + E++ L ++ AR KEK Q + L
Sbjct: 1004 DDLKLTLAK-AEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAE 1062
Query: 159 --QVENVTKEKITISKTCERLEITISE---LHIKIEELNR-----------TIVDITSHK 202
+V +TK K+ + + E LE ++ + L + E R ++ D K
Sbjct: 1063 EDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDK 1122
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L ++ + E+ L + +E+ L +Q+ + A+ +VE
Sbjct: 1123 QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVE 1182
Query: 263 -------IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+LE + +LEE A K E+G R +
Sbjct: 1183 KQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALR 1242
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
K + +L +EK+KS L+ EV+ L ++E +K E
Sbjct: 1243 RKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE 1302
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E K ++EE ++ D ++ LQ S EL + E+K+ L
Sbjct: 1303 DQLSEAKIKVEE----LQRQLADASTQRGRLQTESGELSRLLEEKECL 1346
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/402 (17%), Positives = 154/402 (38%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + D + + Q +E+ K L + ++ LEEAEG E + + E
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +++ ++ E +E L++ +Q V Q +D T+ + A + K K + ++ +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L Q+ + T++ ++ + E +E R ++ Q L + L E
Sbjct: 1674 LELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 1733
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + ++E DL + ++EE
Sbjct: 1734 LEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEA 1793
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
++ R + E + KA + + A
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1853
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
+ +KQ +L+++V L +L+ E K + ER E+ + EE + +
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARM 1913
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
Q + Q++++ + ++ +Q + + +K +L DA
Sbjct: 1914 QDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDA 1955
Score = 72.5 bits (170), Expect = 3e-12
Identities = 89/478 (18%), Positives = 183/478 (38%), Gaps = 18/478 (3%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
SA A RLE ++ ++ LE E++LR ER K L + E + +A +
Sbjct: 1067 SALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLE 1126
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E +K+D+EL +L +ED L + +K+ Q + +E+++ +AR EK++
Sbjct: 1127 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL-QARAEELEEELEAERAARARVEKQR 1185
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRL 205
++ E+ EL ++E + C + E + L ++EE R + + +++
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
++ EL ++V L+ + + KS++ + E L
Sbjct: 1246 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1305
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++++EE L+RQL A+ + G +++ + S
Sbjct: 1306 SEAKIKVEE-------LQRQLADASTQRGRLQTE-SGELSRLLEEKECLISQLSRGKALA 1357
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIID---LEKANGTARELQKRTEQ-LERVNIEI 381
L ++ K KS L V+ L D L + + E Q ++ L + N E+
Sbjct: 1358 AQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEV 1417
Query: 382 ---KSRLE-ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+S+ E + +Q E+ + + LQ ++ + +L + ++ + D
Sbjct: 1418 AQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDV 1477
Query: 438 RANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
+ +E + +A ++ S+ L E + RH
Sbjct: 1478 TLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1535
Score = 64.5 bits (150), Expect = 8e-10
Identities = 87/423 (20%), Positives = 174/423 (41%), Gaps = 41/423 (9%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E +A + L L + + + E I +EK DL++Q+ + L +AE
Sbjct: 897 ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 956
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLL--KKKNQEIVIDFQEQIDQLTKTKARA 142
+ + + ++ +L + LED E E A L ++K ++ + ++ ID L T A+A
Sbjct: 957 LIKSKVQLEGKVKELSERLED---EEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKA 1013
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
EKEK + +V+N+T+E + ++ RL E E + + D+ + +
Sbjct: 1014 EKEKQATE-------NKVKNLTEEMAALDESVARL---TKEKKALQEAHQQALGDLQAEE 1063
Query: 203 QR---LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
R L++ + L ++V+DL+ ++E L+ +
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMD---------------------TERAKR 1102
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
++E DL+ + + + ++ + LE +L K + E+ + +
Sbjct: 1103 KLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
A+ VEKQ++ E+E L LE+A G + ++ + E
Sbjct: 1163 RAEELEEELEAERAARA-RVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELG 1221
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
++ LEE +E T LR KQ E + ++D + + L +E ++ ++ D
Sbjct: 1222 RLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLA 1281
Query: 439 ANI 441
AN+
Sbjct: 1282 ANV 1284
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/418 (19%), Positives = 160/418 (38%), Gaps = 16/418 (3%)
Query: 18 GTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE 77
G N + S+ A RL+ + + +LE +++++ L + + + EE
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1511
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E+ +R TEL +LR E+ LE+ ET K QE + D +Q+ K
Sbjct: 1512 MQRELEAAQRESRGLGTELFRLRHGHEEA-LEALETLKRENKNLQEEISDLTDQVSLSGK 1570
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV 196
+ EK K + E E+ A +E ++ +KT R+++ +S++ +++
Sbjct: 1571 SIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTL-RIQLELSQVKAEVDRKLAEKD 1629
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ ++ +R Q +E ++ D + N + LK ++
Sbjct: 1630 EECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQ 1689
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A+ ++ QL+EE R D E++L E +
Sbjct: 1690 AATRLMQ-------AQLKEEQAGR-DEEQRLAAELHEQAQALERRASLLAAELEELRAAL 1741
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE-LQKRTEQL 374
+ ++N + Q + L ++ + L DL + +G E Q+R E
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801
Query: 375 ERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD-KTREQKDALARENKK 429
E+ I + + E ++ + T L + L++ EL + E + A R KK
Sbjct: 1802 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKK 1859
Score = 50.8 bits (116), Expect = 1e-05
Identities = 96/499 (19%), Positives = 197/499 (39%), Gaps = 48/499 (9%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA 82
+ + A ++AL R + + + + ++S + +RQ++E+EK++L ++V L+ +E
Sbjct: 1232 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 1291
Query: 83 ESQFEINRKRDTELLK-------LRKLLED-------VHLESEETAHLLKKKN------- 121
S ++ R + +L + L++ L D + ES E + LL++K
Sbjct: 1292 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 1351
Query: 122 ------QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
+ + + + Q+++ +K K+ + + L Q E + + + +
Sbjct: 1352 RGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLS 1411
Query: 176 RLEITISELHIKIEE--LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+ +++ K E + RT ++ K++L+ E + V+ ++ K ++
Sbjct: 1412 KANAEVAQWRSKYEADAIQRT-EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRL 1470
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
++ +E LE R Q EEE + L+ ++ + G
Sbjct: 1471 QTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ-EEEMQRELEAAQRESRGLGT- 1528
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK-INNVEKQKSRLQSEVEV 352
+R + K +L K I +EK K L+ E
Sbjct: 1529 ELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSE 1588
Query: 353 LIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR-NKQTELQRVSH 411
+ LE+A G + +T +++ ++K+ ++ + ++ +LR N Q ++ +
Sbjct: 1589 IQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQA 1648
Query: 412 ELD-KTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYK 470
LD +TR + +AL R KKM DL+D + A K
Sbjct: 1649 SLDAETRARNEAL-RLKKKMEGDLNDLELQL-------GHATRQATEAQAATRLMQAQLK 1700
Query: 471 EAEAGRKAEEQRSQRLTAE 489
E +AGR E QRL AE
Sbjct: 1701 EEQAGRDEE----QRLAAE 1715
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER-- 74
G D+ ++ + + RL+Q L+ E+ R +R A+L Q L R
Sbjct: 1669 GDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRAS 1728
Query: 75 -----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDF 128
LEE E R + ELL+ + L +H S+ T L +KK E +
Sbjct: 1729 LLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH--SQNTGLLNQKKKLEADLAQL 1786
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
++++ + + AE++ K + + +++ + + + LE T+ EL ++
Sbjct: 1787 SGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARL 1846
Query: 189 EE 190
EE
Sbjct: 1847 EE 1848
Score = 31.9 bits (69), Expect = 5.5
Identities = 25/160 (15%), Positives = 62/160 (38%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+++ + K K RL+ +VE L LE+ + ++ +LE + + + Q +Q
Sbjct: 1065 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXX 454
+ L+ K +EL ++S ++ + + ++ K++ + +
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 455 XXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +EA + + ++ AE G+ R
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 235 bits (576), Expect = 2e-61
Identities = 140/462 (30%), Positives = 230/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ + ++++LE+ER R R+E+++A+ + ++ +LSERLEEA G + Q E RKR
Sbjct: 1157 IKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKR 1216
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ EL +LR+ LE+ L E T L++K E + EQ+D L + + + EKEKS+ + E
Sbjct: 1217 EAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRME 1276
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
V +L A VE +T+ K + K C E +SE IK+EEL R + D ++ + RL E+ EL
Sbjct: 1277 VDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL 1336
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+ +++ + I + K+ A ++ + D + +R Q
Sbjct: 1337 SRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQH 1396
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WRSK+ K +
Sbjct: 1397 EEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAA 1456
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E E + ++LE+A A L K+ LER E + + EE +
Sbjct: 1457 NAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQREL 1516
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E QR+ R TEL R+ H ++ E + L RENK + +++ D ++
Sbjct: 1517 EAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE 1576
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAE + EE ++ R+ E Q +
Sbjct: 1577 KTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1618
Score = 74.1 bits (174), Expect = 1e-12
Identities = 91/408 (22%), Positives = 159/408 (38%), Gaps = 33/408 (8%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
QD+L E + + K L +V +LSERLE+ E RK + E +L+K +
Sbjct: 944 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1003
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA----- 158
+D+ L + A K+ + V + E++ L ++ AR KEK Q + L
Sbjct: 1004 DDLKLTLAK-AEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAE 1062
Query: 159 --QVENVTKEKITISKTCERLEITISE---LHIKIEELNR-----------TIVDITSHK 202
+V +TK K+ + + E LE ++ + L + E R ++ D K
Sbjct: 1063 EDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDK 1122
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L ++ + E+ L + +E+ L +Q+ + A+ +VE
Sbjct: 1123 QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVE 1182
Query: 263 -------IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+LE + +LEE A K E+G R +
Sbjct: 1183 KQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALR 1242
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
K + +L +EK+KS L+ EV+ L ++E +K E
Sbjct: 1243 RKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE 1302
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E K ++EE ++ D ++ LQ S EL + E+K+ L
Sbjct: 1303 DQLSEAKIKVEE----LQRQLADASTQRGRLQTESGELSRLLEEKECL 1346
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/402 (17%), Positives = 154/402 (38%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + D + + Q +E+ K L + ++ LEEAEG E + + E
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +++ ++ E +E L++ +Q V Q +D T+ + A + K K + ++ +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L Q+ + T++ ++ + E +E R ++ Q L + L E
Sbjct: 1674 LELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 1733
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + ++E DL + ++EE
Sbjct: 1734 LEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEA 1793
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
++ R + E + KA + + A
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1853
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
+ +KQ +L+++V L +L+ E K + ER E+ + EE + +
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARM 1913
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
Q + Q++++ + ++ +Q + + +K +L DA
Sbjct: 1914 QDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDA 1955
Score = 72.5 bits (170), Expect = 3e-12
Identities = 89/478 (18%), Positives = 183/478 (38%), Gaps = 18/478 (3%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
SA A RLE ++ ++ LE E++LR ER K L + E + +A +
Sbjct: 1067 SALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLE 1126
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E +K+D+EL +L +ED L + +K+ Q + +E+++ +AR EK++
Sbjct: 1127 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL-QARAEELEEELEAERAARARVEKQR 1185
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRL 205
++ E+ EL ++E + C + E + L ++EE R + + +++
Sbjct: 1186 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1245
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
++ EL ++V L+ + + KS++ + E L
Sbjct: 1246 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1305
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++++EE L+RQL A+ + G +++ + S
Sbjct: 1306 SEAKIKVEE-------LQRQLADASTQRGRLQTE-SGELSRLLEEKECLISQLSRGKALA 1357
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIID---LEKANGTARELQKRTEQ-LERVNIEI 381
L ++ K KS L V+ L D L + + E Q ++ L + N E+
Sbjct: 1358 AQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEV 1417
Query: 382 ---KSRLE-ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+S+ E + +Q E+ + + LQ ++ + +L + ++ + D
Sbjct: 1418 AQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDV 1477
Query: 438 RANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
+ +E + +A ++ S+ L E + RH
Sbjct: 1478 TLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1535
Score = 64.5 bits (150), Expect = 8e-10
Identities = 87/423 (20%), Positives = 174/423 (41%), Gaps = 41/423 (9%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E +A + L L + + + E I +EK DL++Q+ + L +AE
Sbjct: 897 ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 956
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLL--KKKNQEIVIDFQEQIDQLTKTKARA 142
+ + + ++ +L + LED E E A L ++K ++ + ++ ID L T A+A
Sbjct: 957 LIKSKVQLEGKVKELSERLED---EEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKA 1013
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
EKEK + +V+N+T+E + ++ RL E E + + D+ + +
Sbjct: 1014 EKEKQATE-------NKVKNLTEEMAALDESVARL---TKEKKALQEAHQQALGDLQAEE 1063
Query: 203 QR---LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
R L++ + L ++V+DL+ ++E L+ +
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMD---------------------TERAKR 1102
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
++E DL+ + + + ++ + LE +L K + E+ + +
Sbjct: 1103 KLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
A+ VEKQ++ E+E L LE+A G + ++ + E
Sbjct: 1163 RAEELEEELEAERAARA-RVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELG 1221
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
++ LEE +E T LR KQ E + ++D + + L +E ++ ++ D
Sbjct: 1222 RLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLA 1281
Query: 439 ANI 441
AN+
Sbjct: 1282 ANV 1284
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/418 (19%), Positives = 160/418 (38%), Gaps = 16/418 (3%)
Query: 18 GTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE 77
G N + S+ A RL+ + + +LE +++++ L + + + EE
Sbjct: 1452 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1511
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E+ +R TEL +LR E+ LE+ ET K QE + D +Q+ K
Sbjct: 1512 MQRELEAAQRESRGLGTELFRLRHGHEEA-LEALETLKRENKNLQEEISDLTDQVSLSGK 1570
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV 196
+ EK K + E E+ A +E ++ +KT R+++ +S++ +++
Sbjct: 1571 SIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTL-RIQLELSQVKAEVDRKLAEKD 1629
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ ++ +R Q +E ++ D + N + LK ++
Sbjct: 1630 EECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQ 1689
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A+ ++ QL+EE R D E++L E +
Sbjct: 1690 AATRLMQ-------AQLKEEQAGR-DEEQRLAAELHEQAQALERRASLLAAELEELRAAL 1741
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE-LQKRTEQL 374
+ ++N + Q + L ++ + L DL + +G E Q+R E
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1801
Query: 375 ERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD-KTREQKDALARENKK 429
E+ I + + E ++ + T L + L++ EL + E + A R KK
Sbjct: 1802 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKK 1859
Score = 50.8 bits (116), Expect = 1e-05
Identities = 96/499 (19%), Positives = 197/499 (39%), Gaps = 48/499 (9%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA 82
+ + A ++AL R + + + + ++S + +RQ++E+EK++L ++V L+ +E
Sbjct: 1232 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 1291
Query: 83 ESQFEINRKRDTELLK-------LRKLLED-------VHLESEETAHLLKKKN------- 121
S ++ R + +L + L++ L D + ES E + LL++K
Sbjct: 1292 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 1351
Query: 122 ------QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
+ + + + Q+++ +K K+ + + L Q E + + + +
Sbjct: 1352 RGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLS 1411
Query: 176 RLEITISELHIKIEE--LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+ +++ K E + RT ++ K++L+ E + V+ ++ K ++
Sbjct: 1412 KANAEVAQWRSKYEADAIQRT-EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRL 1470
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
++ +E LE R Q EEE + L+ ++ + G
Sbjct: 1471 QTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ-EEEMQRELEAAQRESRGLGT- 1528
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK-INNVEKQKSRLQSEVEV 352
+R + K +L K I +EK K L+ E
Sbjct: 1529 ELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSE 1588
Query: 353 LIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR-NKQTELQRVSH 411
+ LE+A G + +T +++ ++K+ ++ + ++ +LR N Q ++ +
Sbjct: 1589 IQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQA 1648
Query: 412 ELD-KTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYK 470
LD +TR + +AL R KKM DL+D + A K
Sbjct: 1649 SLDAETRARNEAL-RLKKKMEGDLNDLELQL-------GHATRQATEAQAATRLMQAQLK 1700
Query: 471 EAEAGRKAEEQRSQRLTAE 489
E +AGR E QRL AE
Sbjct: 1701 EEQAGRDEE----QRLAAE 1715
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER-- 74
G D+ ++ + + RL+Q L+ E+ R +R A+L Q L R
Sbjct: 1669 GDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRAS 1728
Query: 75 -----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDF 128
LEE E R + ELL+ + L +H S+ T L +KK E +
Sbjct: 1729 LLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH--SQNTGLLNQKKKLEADLAQL 1786
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
++++ + + AE++ K + + +++ + + + LE T+ EL ++
Sbjct: 1787 SGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARL 1846
Query: 189 EE 190
EE
Sbjct: 1847 EE 1848
Score = 31.9 bits (69), Expect = 5.5
Identities = 25/160 (15%), Positives = 62/160 (38%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+++ + K K RL+ +VE L LE+ + ++ +LE + + + Q +Q
Sbjct: 1065 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1124
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXX 454
+ L+ K +EL ++S ++ + + ++ K++ + +
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1184
Query: 455 XXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +EA + + ++ AE G+ R
Sbjct: 1185 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1224
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 235 bits (576), Expect = 2e-61
Identities = 140/462 (30%), Positives = 230/462 (49%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ + ++++LE+ER R R+E+++A+ + ++ +LSERLEEA G + Q E RKR
Sbjct: 1184 IKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKR 1243
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ EL +LR+ LE+ L E T L++K E + EQ+D L + + + EKEKS+ + E
Sbjct: 1244 EAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRME 1303
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
V +L A VE +T+ K + K C E +SE IK+EEL R + D ++ + RL E+ EL
Sbjct: 1304 VDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGEL 1363
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+ +++ + I + K+ A ++ + D + +R Q
Sbjct: 1364 SRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQH 1423
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE+EA+ +L+R L KAN E+ WRSK+ K +
Sbjct: 1424 EEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAA 1483
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK +++EK K RLQ+E E + ++LE+A A L K+ LER E + + EE +
Sbjct: 1484 NAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQREL 1543
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E QR+ R TEL R+ H ++ E + L RENK + +++ D ++
Sbjct: 1544 EAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE 1603
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAE + EE ++ R+ E Q +
Sbjct: 1604 KTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVK 1645
Score = 74.5 bits (175), Expect = 8e-13
Identities = 91/408 (22%), Positives = 159/408 (38%), Gaps = 33/408 (8%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
QD+L E + + K L +V +LSERLE+ E RK + E +L+K +
Sbjct: 971 QDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDI 1030
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA----- 158
+D+ L + A K+ + V + E++ L ++ AR KEK Q + L
Sbjct: 1031 DDLELTLAK-AEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAE 1089
Query: 159 --QVENVTKEKITISKTCERLEITISE---LHIKIEELNR-----------TIVDITSHK 202
+V +TK K+ + + E LE ++ + L + E R ++ D K
Sbjct: 1090 EDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDK 1149
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L ++ + E+ L + +E+ L +Q+ + A+ +VE
Sbjct: 1150 QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVE 1209
Query: 263 -------IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+LE + +LEE A K E+G R +
Sbjct: 1210 KQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALR 1269
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
K + +L +EK+KS L+ EV+ L ++E +K E
Sbjct: 1270 RKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE 1329
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E K ++EE ++ D ++ LQ S EL + E+K+ L
Sbjct: 1330 DQLSEAKIKVEE----LQRQLADASTQRGRLQTESGELSRLLEEKECL 1373
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/402 (17%), Positives = 154/402 (38%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + D + + Q +E+ K L + ++ LEEAEG E + + E
Sbjct: 1581 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1640
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +++ ++ E +E L++ +Q V Q +D T+ + A + K K + ++ +
Sbjct: 1641 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1700
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L Q+ + T++ ++ + E +E R ++ Q L + L E
Sbjct: 1701 LELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 1760
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + ++E DL + ++EE
Sbjct: 1761 LEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEA 1820
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
++ R + E + KA + + A
Sbjct: 1821 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1880
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
+ +KQ +L+++V L +L+ E K + ER E+ + EE + +
Sbjct: 1881 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARM 1940
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
Q + Q++++ + ++ +Q + + +K +L DA
Sbjct: 1941 QDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDA 1982
Score = 72.5 bits (170), Expect = 3e-12
Identities = 89/478 (18%), Positives = 183/478 (38%), Gaps = 18/478 (3%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
SA A RLE ++ ++ LE E++LR ER K L + E + +A +
Sbjct: 1094 SALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLE 1153
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E +K+D+EL +L +ED L + +K+ Q + +E+++ +AR EK++
Sbjct: 1154 EKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL-QARAEELEEELEAERAARARVEKQR 1212
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRL 205
++ E+ EL ++E + C + E + L ++EE R + + +++
Sbjct: 1213 AEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQ 1272
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
++ EL ++V L+ + + KS++ + E L
Sbjct: 1273 AEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQL 1332
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++++EE L+RQL A+ + G +++ + S
Sbjct: 1333 SEAKIKVEE-------LQRQLADASTQRGRLQTE-SGELSRLLEEKECLISQLSRGKALA 1384
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIID---LEKANGTARELQKRTEQ-LERVNIEI 381
L ++ K KS L V+ L D L + + E Q ++ L + N E+
Sbjct: 1385 AQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEV 1444
Query: 382 ---KSRLE-ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+S+ E + +Q E+ + + LQ ++ + +L + ++ + D
Sbjct: 1445 AQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDV 1504
Query: 438 RANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
+ +E + +A ++ S+ L E + RH
Sbjct: 1505 TLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRH 1562
Score = 64.5 bits (150), Expect = 8e-10
Identities = 87/423 (20%), Positives = 174/423 (41%), Gaps = 41/423 (9%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E +A + L L + + + E I +EK DL++Q+ + L +AE
Sbjct: 924 ELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHL 983
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLL--KKKNQEIVIDFQEQIDQLTKTKARA 142
+ + + ++ +L + LED E E A L ++K ++ + ++ ID L T A+A
Sbjct: 984 LIKSKVQLEGKVKELSERLED---EEEVNADLAARRRKLEDECTELKKDIDDLELTLAKA 1040
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
EKEK + +V+N+T+E + ++ RL E E + + D+ + +
Sbjct: 1041 EKEKQATE-------NKVKNLTEEMAALDESVARL---TKEKKALQEAHQQALGDLQAEE 1090
Query: 203 QR---LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
R L++ + L ++V+DL+ ++E L+ +
Sbjct: 1091 DRVSALTKAKLRLEQQVEDLECSLEQEKKLRMD---------------------TERAKR 1129
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
++E DL+ + + + ++ + LE +L K + E+ + +
Sbjct: 1130 KLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1189
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
A+ VEKQ++ E+E L LE+A G + ++ + E
Sbjct: 1190 RAEELEEELEAERAARA-RVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELG 1248
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTE-LQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
++ LEE +E T LR KQ E + ++D + + L +E ++ ++ D
Sbjct: 1249 RLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLA 1308
Query: 439 ANI 441
AN+
Sbjct: 1309 ANV 1311
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/418 (19%), Positives = 160/418 (38%), Gaps = 16/418 (3%)
Query: 18 GTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE 77
G N + S+ A RL+ + + +LE +++++ L + + + EE
Sbjct: 1479 GVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEE 1538
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E+ +R TEL +LR E+ LE+ ET K QE + D +Q+ K
Sbjct: 1539 MQRELEAAQRESRGLGTELFRLRHGHEEA-LEALETLKRENKNLQEEISDLTDQVSLSGK 1597
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV 196
+ EK K + E E+ A +E ++ +KT R+++ +S++ +++
Sbjct: 1598 SIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTL-RIQLELSQVKAEVDRKLAEKD 1656
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ ++ +R Q +E ++ D + N + LK ++
Sbjct: 1657 EECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQ 1716
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A+ ++ QL+EE R D E++L E +
Sbjct: 1717 AATRLMQ-------AQLKEEQAGR-DEEQRLAAELHEQAQALERRASLLAAELEELRAAL 1768
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE-LQKRTEQL 374
+ ++N + Q + L ++ + L DL + +G E Q+R E
Sbjct: 1769 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAE 1828
Query: 375 ERVN--IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD-KTREQKDALARENKK 429
E+ I + + E ++ + T L + L++ EL + E + A R KK
Sbjct: 1829 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKK 1886
Score = 50.8 bits (116), Expect = 1e-05
Identities = 96/499 (19%), Positives = 197/499 (39%), Gaps = 48/499 (9%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA 82
+ + A ++AL R + + + + ++S + +RQ++E+EK++L ++V L+ +E
Sbjct: 1259 LRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAK 1318
Query: 83 ESQFEINRKRDTELLK-------LRKLLED-------VHLESEETAHLLKKKN------- 121
S ++ R + +L + L++ L D + ES E + LL++K
Sbjct: 1319 ASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLS 1378
Query: 122 ------QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
+ + + + Q+++ +K K+ + + L Q E + + + +
Sbjct: 1379 RGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLS 1438
Query: 176 RLEITISELHIKIEE--LNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+ +++ K E + RT ++ K++L+ E + V+ ++ K ++
Sbjct: 1439 KANAEVAQWRSKYEADAIQRT-EELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRL 1497
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
++ +E LE R Q EEE + L+ ++ + G
Sbjct: 1498 QTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ-EEEMQRELEAAQRESRGLGT- 1555
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK-INNVEKQKSRLQSEVEV 352
+R + K +L K I +EK K L+ E
Sbjct: 1556 ELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSE 1615
Query: 353 LIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR-NKQTELQRVSH 411
+ LE+A G + +T +++ ++K+ ++ + ++ +LR N Q ++ +
Sbjct: 1616 IQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQA 1675
Query: 412 ELD-KTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYK 470
LD +TR + +AL R KKM DL+D + A K
Sbjct: 1676 SLDAETRARNEAL-RLKKKMEGDLNDLELQL-------GHATRQATEAQAATRLMQAQLK 1727
Query: 471 EAEAGRKAEEQRSQRLTAE 489
E +AGR E QRL AE
Sbjct: 1728 EEQAGRDEE----QRLAAE 1742
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/182 (21%), Positives = 76/182 (41%), Gaps = 10/182 (5%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER-- 74
G D+ ++ + + RL+Q L+ E+ R +R A+L Q L R
Sbjct: 1696 GDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRAS 1755
Query: 75 -----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDF 128
LEE E R + ELL+ + L +H S+ T L +KK E +
Sbjct: 1756 LLAAELEELRAALEQGERSRRLAEQELLEATERLNLLH--SQNTGLLNQKKKLEADLAQL 1813
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
++++ + + AE++ K + + +++ + + + LE T+ EL ++
Sbjct: 1814 SGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARL 1873
Query: 189 EE 190
EE
Sbjct: 1874 EE 1875
Score = 31.9 bits (69), Expect = 5.5
Identities = 25/160 (15%), Positives = 62/160 (38%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+++ + K K RL+ +VE L LE+ + ++ +LE + + + Q +Q
Sbjct: 1092 RVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQ 1151
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXX 454
+ L+ K +EL ++S ++ + + ++ K++ + +
Sbjct: 1152 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQ 1211
Query: 455 XXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +EA + + ++ AE G+ R
Sbjct: 1212 RAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLR 1251
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 230 bits (562), Expect = 1e-59
Identities = 135/462 (29%), Positives = 226/462 (48%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I + +++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 1111 IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKR 1170
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E KLR+ LE+ L+ E L+KK+ + + + EQID L + K + EKEKS+ + E
Sbjct: 1171 EAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME 1230
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+L + E ++K K + K C LE +S L K EE R I D+T+ + RL E E
Sbjct: 1231 TDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEY 1290
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ + + + K Q +L D + +R Q
Sbjct: 1291 SRQLDEQDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQY 1350
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L+R L KAN E+ WR+K+ K + +
Sbjct: 1351 EEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAV 1410
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
AK ++EK K RLQ+EVE L++D+E++N L K+ ++V E K + EET
Sbjct: 1411 NAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAEL 1470
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
E +Q++ R+ TEL +V + +++ +Q + L R +K + ++ D I
Sbjct: 1471 EASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELE 1530
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1531 KIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
Score = 72.1 bits (169), Expect = 4e-12
Identities = 72/407 (17%), Positives = 166/407 (40%), Gaps = 12/407 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+ +++ A ++AL + D + + + +++ + ++Q++E+EK++L ++ LS E
Sbjct: 1183 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAIS 1242
Query: 80 GGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
++ R + ++ L+ K E L ++ TA + + Q ++ Q+D+
Sbjct: 1243 KAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQ--RARLQTEAGEYSRQLDEQDAL 1300
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ + K ++ EL Q+E TK K ++ + L + EE ++
Sbjct: 1301 VSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL 1360
Query: 199 TSHKQRLSQENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ LS+ N E+ K D E + K ++A +
Sbjct: 1361 ---QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASL 1417
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ +++ ++E + + +E + A L+++ + + W+ K+
Sbjct: 1418 EKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 1477
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
S + ++ + + LQ E+ L + + EL+K +Q+
Sbjct: 1478 RS-LSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+ EI++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1537 EQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1583
Score = 62.1 bits (144), Expect = 5e-09
Identities = 71/460 (15%), Positives = 171/460 (37%), Gaps = 4/460 (0%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A ++LE ++ ++ LE E++LR +ER K L + E + E + E K
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK 1085
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
++ E+ L +ED + +K+ Q + + E+I+ ++A+AEK++S
Sbjct: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKEL-QARIEELGEEIEAERASRAKAEKQRSDLSR 1144
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN-RTIVDITSHKQRLSQENI 210
E+ E+ ++E + ++ E +L +EE + + + +++ +
Sbjct: 1145 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 1204
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL +++ +L+ + + KS++ + +E + ++
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKT 1264
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
+ EE+ DL Q + E G + +
Sbjct: 1265 KEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEELKHQLEE 1324
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE-ETV 389
AK N + + + ++L E+ ELQ+ + + +++ E + +
Sbjct: 1325 ETKAK-NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1383
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXX 449
Q E+ + + LQ ++ + +L + +++ +++ D ++
Sbjct: 1384 QRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
Query: 450 XXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
Y+E +A +A ++ S+ L+ E
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTE 1483
Score = 58.8 bits (136), Expect = 4e-08
Identities = 75/413 (18%), Positives = 162/413 (39%), Gaps = 16/413 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ + +D+L R+ +E +EK DL +QV ++ L +AE E
Sbjct: 852 MATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQL 911
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAE 143
I K E K++++ E E E A L KK ++ + ++ ID L T A+ E
Sbjct: 912 --IKNKIQLEA-KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+K + +V L ++ + + +SK + L+ T + ++ + +T K
Sbjct: 969 KQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+L Q+ +L ++ K ++ K ++ L + E
Sbjct: 1029 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF 1088
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
++ ++ ++E+E + L++++ + I +
Sbjct: 1089 EISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A VE K R ++E + L DLE+A + + L + + + +
Sbjct: 1149 ISERLEEAGGATSAQVELNKKR-EAEFQKLRRDLEEA---TLQHEAMVAALRKKHADSMA 1204
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
L E + ++ ++ L +++EL+ + +L E +KM L D
Sbjct: 1205 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLED 1257
Score = 56.4 bits (130), Expect = 2e-07
Identities = 82/441 (18%), Positives = 168/441 (38%), Gaps = 36/441 (8%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
++ ++E+ ++++ +++ L ++ + D + Q E E EG AE Q ++
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE---EQEGKAELQRALS- 1365
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
K ++E+ + R E ++ E KKK + + + +E ++ + A EK K + Q
Sbjct: 1366 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 1425
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
EV +L+ VE + K + +SE K EE + + LS E
Sbjct: 1426 NEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELF 1485
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
++ ++ +E + + + QVE + ++
Sbjct: 1486 KVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA 1545
Query: 271 QLEEESEARLDLER-QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
LEE +EA L+ E ++++ E+ +S+ ++
Sbjct: 1546 ALEE-AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTL 1604
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE----------LQKRT-------- 371
I N+ + K +++ ++ + I L AN A E + K T
Sbjct: 1605 DAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDAL 1664
Query: 372 -------EQL----ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
EQL R N+ +++ +EE EQT+R + + EL S + Q
Sbjct: 1665 RGQEDLKEQLAIVERRANL-LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQN 1723
Query: 421 DALARENKKMGDDLHDARANI 441
+L KK+ +D+ ++ +
Sbjct: 1724 TSLINTKKKLENDVSQLQSEV 1744
Score = 52.4 bits (120), Expect = 4e-06
Identities = 89/433 (20%), Positives = 177/433 (40%), Gaps = 46/433 (10%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE +
Sbjct: 1410 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 1469
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL K++ + E+ L+ ET K Q+ + D EQI
Sbjct: 1470 LEASQKESRSLSTELFKVKNVYEE-SLDQLETLRRAHKNLQQEISDLTEQI--------- 1519
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE-----LHIKIE------E 190
AE K +++EL + V +EK I E E ++ L I++E E
Sbjct: 1520 AEGGK-----QIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE 1574
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXX 246
++R I + +L + + +V+ +Q D ++ N + +K ++
Sbjct: 1575 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1634
Query: 247 XXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGH-WRS 298
+ + L+ ++ L++ + DL+ QL +AN EI W +
Sbjct: 1635 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1694
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL- 357
S +LI +E S+LQSEVE +I +
Sbjct: 1695 --LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1752
Query: 358 ---EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
EKA + E+L++ + + LE + EQT +DL+++ E ++++ +
Sbjct: 1753 NAEEKAKKAITDAAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1811
Query: 415 KTREQK-DALARE 426
K + QK +A RE
Sbjct: 1812 KKQIQKLEARVRE 1824
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/192 (18%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E ++ ER + +++ SER++ S +K
Sbjct: 1674 LAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1733
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ ++ +L+ +E+V ES KK + + E++ + T A E+ K +
Sbjct: 1734 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1792
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + + ++ + E
Sbjct: 1793 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHDRRVKE 1852
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 1853 LTYQTEEDRKNV 1864
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 226 bits (553), Expect = 1e-58
Identities = 137/463 (29%), Positives = 226/463 (48%), Gaps = 1/463 (0%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I + +++E+ER R + E++++DLS ++ ++SERLEEA G +Q E+N+KR
Sbjct: 610 IKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKR 669
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ E KLR+ LE+ L+ E L+KK+ + + + EQID L + K + EKEKS+ + E
Sbjct: 670 EAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME 729
Query: 153 VYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
+L + E ++K K + K R LE +SEL K EE R I D+T+ + RL E E
Sbjct: 730 TDDLSSNAEAISKAKGNLEKDGGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGE 789
Query: 212 LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
+++ + + + K Q +L D + +R Q
Sbjct: 790 YSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQ 849
Query: 272 LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
EEE E + +L+R L KAN E+ WR+ K +
Sbjct: 850 YEEEQEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEA 909
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
+ AK ++EK K RLQ+EVE L++D+E++N L K+ ++V E K + EET
Sbjct: 910 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 969
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXX 451
E +Q++ R+ TEL +V + +++ +Q + L RENK + ++ D I
Sbjct: 970 LEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHEL 1029
Query: 452 XXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
AA +EAEA + EE + R+ E Q +
Sbjct: 1030 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1072
Score = 74.5 bits (175), Expect = 8e-13
Identities = 71/407 (17%), Positives = 169/407 (41%), Gaps = 11/407 (2%)
Query: 21 DVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIEREKADLSVQVIQLS---ERLE 76
+ +++ A ++AL + D + + + +++ + ++Q++E+EK++L ++ LS E +
Sbjct: 682 EATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAIS 741
Query: 77 EAEGGAESQFEINRKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
+A+G E + R + ++ +L+ K E L ++ TA + + Q ++ Q+D+
Sbjct: 742 KAKGNLEK--DGGRSLEDQVSELKTKEEEQQRLINDLTAQ--RARLQTEAGEYSRQLDEK 797
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
++ + K ++ EL Q+E TK K ++ + L + EE
Sbjct: 798 DALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGK 857
Query: 196 VDITSHKQRLSQENIELVKEVQ-DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ + + E + + D E + K ++A +
Sbjct: 858 AELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASL 917
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ +++ ++E + + +E + A L+++ + + W+ K+
Sbjct: 918 EKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES 977
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
S + ++ + ++ LQ E+ L + + EL+K +Q+
Sbjct: 978 RS-LSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1036
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
E+ EI++ LEE E + + Q EL +V E+D+ +KD
Sbjct: 1037 EQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKD 1083
Score = 58.8 bits (136), Expect = 4e-08
Identities = 77/414 (18%), Positives = 162/414 (39%), Gaps = 17/414 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIE-------REKADLSVQVIQLSERLEEAEGGAESQ 85
++ ++++ + +D+L R+ +E +EK DL +QV ++ L +AE E
Sbjct: 351 MATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQL 410
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAE 143
I K E K++++ E E E A L KK ++ + ++ ID L T A+ E
Sbjct: 411 --IKNKIQLEA-KIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 467
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
KEK + +V L ++ + + +SK + L+ T + ++ + +T K
Sbjct: 468 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 527
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+L Q+ +L ++ K ++ K ++ L + E
Sbjct: 528 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKKEF 587
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
++ ++ ++E+E + L++++ + I +
Sbjct: 588 EISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 647
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
A VE K R ++E + L DLE+A + + L + + + +
Sbjct: 648 ISERLEEAGGATSAQVELNKKR-EAEFQKLRRDLEEA---TLQHEAMVAALRKKHADSMA 703
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ-KDALARENKKMGDDLHD 436
L E + ++ ++ L +++EL+ + +L E A K G L D
Sbjct: 704 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLED 757
Score = 56.8 bits (131), Expect = 2e-07
Identities = 79/407 (19%), Positives = 155/407 (38%), Gaps = 26/407 (6%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A ++LE ++ ++ LE E++LR +ER K L + E + E + E K
Sbjct: 525 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEK 584
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
++ E+ L +ED + +K+ Q + + E+I+ ++A+AEK++S
Sbjct: 585 KEFEISNLISKIEDEQAVEIQLQKKIKEL-QARIEELGEEIEAERASRAKAEKQRSDLSR 643
Query: 152 EVYELLAQVE---NVTKEKITISKTCE----RLEITISELHIKIE--------------- 189
E+ E+ ++E T ++ ++K E +L + E ++ E
Sbjct: 644 ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMA 703
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
EL I ++ KQ+L +E EL E DL N E + K +
Sbjct: 704 ELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQVSELK 763
Query: 250 XXXXXXASLHQVEIDLESVRVQLEE-ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
L ++ + R+Q E E +LD + LV ++
Sbjct: 764 TKEEEQQRLIN-DLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 822
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK-ANGTAREL 367
+ L + ++ K+ LQ + ++ + T +
Sbjct: 823 EEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTNTETDA 882
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
+RTE+LE ++ RL+E + E + + QR+ +E++
Sbjct: 883 IQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 929
Score = 55.6 bits (128), Expect = 4e-07
Identities = 82/441 (18%), Positives = 168/441 (38%), Gaps = 36/441 (8%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
++ ++E+ ++++ +++ L ++ + D + Q E E EG AE Q ++
Sbjct: 810 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE---EQEGKAELQRALS- 865
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
K ++E+ + R E ++ E KKK + + + +E ++ + A EK K + Q
Sbjct: 866 KANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 925
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
EV +L+ VE + K + +SE K EE + + LS E
Sbjct: 926 NEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELF 985
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
++ ++ +E + + + QVE + ++
Sbjct: 986 KVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQA 1045
Query: 271 QLEEESEARLDLER-QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
LEE +EA L+ E ++++ E+ +S+ ++
Sbjct: 1046 ALEE-AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTL 1104
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE----------LQKRT-------- 371
I N+ + K +++ ++ + I L AN A E + K T
Sbjct: 1105 DAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDAL 1164
Query: 372 -------EQL----ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
EQL R N+ +++ +EE EQT+R + + EL S + Q
Sbjct: 1165 RGQEDLKEQLAIVERRANL-LQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQN 1223
Query: 421 DALARENKKMGDDLHDARANI 441
+L KK+ +D+ ++ +
Sbjct: 1224 TSLINTKKKLENDVSQLQSEV 1244
Score = 54.0 bits (124), Expect = 1e-06
Identities = 88/433 (20%), Positives = 182/433 (42%), Gaps = 46/433 (10%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE +
Sbjct: 910 VNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAE 969
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL K++ + E+ L+ ET L+++N+ + Q++I LT+ A
Sbjct: 970 LEASQKESRSLSTELFKVKNVYEE-SLDQLET---LRRENKNL----QQEISDLTEQIAE 1021
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE-----LHIKIE------E 190
K+ ++EL + V +EK I E E ++ L I++E E
Sbjct: 1022 GGKQ-------IHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSE 1074
Query: 191 LNRTIVDITSHKQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXX 246
++R I + +L + + +V+ +Q D ++ N + +K ++
Sbjct: 1075 VDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNH 1134
Query: 247 XXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV----KAN---GEIGH-WRS 298
+ + L+ ++ L++ + DL+ QL +AN EI W +
Sbjct: 1135 ANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWAT 1194
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL- 357
S +LI +E S+LQSEVE +I +
Sbjct: 1195 --LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESR 1252
Query: 358 ---EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
EKA + E+L++ + + LE + EQT +DL+++ E ++++ +
Sbjct: 1253 NAEEKAKKAITDAAMMAEELKKEQ-DTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGG 1311
Query: 415 KTREQK-DALARE 426
K + QK +A RE
Sbjct: 1312 KKQIQKLEARVRE 1324
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/192 (18%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L+ +E + L+Q ++E ++ ER + +++ SER++ S +K
Sbjct: 1174 LAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1233
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ ++ +L+ +E+V ES KK + + E++ + T A E+ K +
Sbjct: 1234 ENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAM-MAEELKKEQDTSAHLERMKKNLEQT 1292
Query: 153 VYELLAQVENVTKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
V +L +++ + + K ++LE + EL ++E + + ++ + E
Sbjct: 1293 VKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKE 1352
Query: 212 LVKEVQDLKVNI 223
L + ++ + N+
Sbjct: 1353 LTYQTEEDRKNV 1364
>AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22037 fis, clone HEP08868. ).
Length = 746
Score = 216 bits (528), Expect = 1e-55
Identities = 129/467 (27%), Positives = 227/467 (48%), Gaps = 2/467 (0%)
Query: 29 DLSALSRLED-KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
DL + + D +I + E E+ L ++R+ + ++ +L E LE AE ++ E
Sbjct: 267 DLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELE-AERAMRAKIE 325
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
NRKR+ ELLKLR+ LE+ L+SE TA L+KK+ + + + E ++ L + K++ EK+K
Sbjct: 326 QNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQ 385
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
+AE+ +L A +E + K K+ +LE ++SE + K+ EL R +I + + RL
Sbjct: 386 VMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELERNQAEINAIRTRLQA 445
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
EN EL +E ++ + + ++ +K+ + SQ SL + DL+
Sbjct: 446 ENSELSREYEESQSRLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDL 505
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
V+ QLEEE + +L+R + K N E+ WR+K+ K +
Sbjct: 506 VKEQLEEEQGGKSELQRLVSKLNTEVTTWRTKYETDAIQRTEELEETKRKLAARLQEAEE 565
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
T A+ ++EK K RLQ+EVE L IDLEKAN A L K+ +++ E + + EE
Sbjct: 566 AAETAQARAASLEKNKQRLQAEVEDLTIDLEKANAAAAALDKKQRLFDKMLAEWQQKCEE 625
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXX 447
+ +Q++ R TE ++ +++ E +++ +ENK + +++ D +
Sbjct: 626 LQVEVDSSQKECRMYMTESFKIKTAYEESLEHLESVKKENKTLQEEIKDLIDQLGEGGRS 685
Query: 448 XXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
A +EAE+ + EE + R+ E Q +
Sbjct: 686 VHELQKLKKKLEMEKEELQVALEEAESSLEVEESKVIRIQLELAQVK 732
Score = 60.5 bits (140), Expect = 1e-08
Identities = 67/390 (17%), Positives = 159/390 (40%), Gaps = 15/390 (3%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELL 97
D + + + +ES + ++ ++E++K + ++ L+ +E + + RK + L
Sbjct: 361 DSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLS 420
Query: 98 KLRKLLEDVHLESEETAHL---LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + ++ E + L+ +N E+ +++E +L + + K+ ++V
Sbjct: 421 EANAKVAELERNQAEINAIRTRLQAENSELSREYEESQSRLNQIL----RIKTSLTSQVD 476
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV- 213
+ Q++ +K + T + L T +L + E+L + ++ +S+ N E+
Sbjct: 477 DYKRQLDEESKSRSTAVVS---LANTKHDLDLVKEQLEEEQGGKSELQRLVSKLNTEVTT 533
Query: 214 ---KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
K D E + K ++A++ + +++ ++E + +
Sbjct: 534 WRTKYETDAIQRTEELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVEDLTI 593
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
LE+ + A L+++ + + W+ K Y
Sbjct: 594 DLEKANAAAAALDKKQRLFDKMLAEWQQKCEELQVEVDSSQKECRM-YMTESFKIKTAYE 652
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
+ + +V+K+ LQ E++ LI L + + ELQK ++LE E++ LEE
Sbjct: 653 ESLEHLESVKKENKTLQEEIKDLIDQLGEGGRSVHELQKLKKKLEMEKEELQVALEEAES 712
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQK 420
E + + Q EL +V ++D+ +K
Sbjct: 713 SLEVEESKVIRIQLELAQVKADIDRRIHEK 742
Score = 54.0 bits (124), Expect = 1e-06
Identities = 81/403 (20%), Positives = 168/403 (41%), Gaps = 44/403 (10%)
Query: 44 QDDLESERELRQR---IEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
Q+ + +EL ++ + +EK DL++Q+ E L +AE + ++++ +R
Sbjct: 56 QELVNKVKELEEKTATLSQEKNDLTIQLQAEQENLMDAEERLTWMMKTKMDLESQISDMR 115
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
+ LE+ + K+K + + D + ++ L T A+ EKEK +V L +
Sbjct: 116 ERLEEEE-GMAASLSAAKRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTLTGDL 174
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
++ ++ IT ++ + + ELH K + + D +H L++ N +L ++ +L+
Sbjct: 175 -SLREDSIT---KLQKEKRALEELHQKTLDDLQAEEDKVNH---LTKNNSKLSTQIHELE 227
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
N E +++++ + + E DL+ L E ++L
Sbjct: 228 DNWEQEKKIRAEVEK---------------------ARRKAESDLKMTIDNLNEMERSKL 266
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS--XXXXXXXXXXXTLIAKINN 338
DLE + K + EI SK+ + AKI
Sbjct: 267 DLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQ 326
Query: 339 VEKQKS---RLQSEVEVLIIDLEKANGTARE-----LQKRTEQLERVNIEIKSRLEETVQ 390
K+++ +L+ E+E + E T R+ + + TE +E + +KS+LE+ Q
Sbjct: 327 NRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHVESLQ-RVKSKLEKDKQ 385
Query: 391 LYEQTQRDLRNKQTELQRVSHELD-KTREQKDALARENKKMGD 432
+ + DL +Q+ + R+ +D+L+ N K+ +
Sbjct: 386 VMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAE 428
Score = 53.6 bits (123), Expect = 2e-06
Identities = 81/402 (20%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+ + DDL++E + + + + LS Q+ +L + E+ + + RK +++
Sbjct: 191 LEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDNWEQEKKIRAEVEKARRKAESD 250
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
L L ++ + ++KK++ EI V E L T R KE E+
Sbjct: 251 LKMTIDNLNEMERSKLDLEEVVKKRDLEINSVNSKYEDEQSLNSTLQRKLKEHQDRIEEL 310
Query: 154 YELL-------AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD----ITSHK 202
E L A++E K + + K LE + L + VD +T H
Sbjct: 311 EEELEAERAMRAKIEQNRKREAELLKLRRELEEAALQSEATASTLRKKHVDSMAELTEHV 370
Query: 203 QRLSQENIELVKEVQDLKVNIENV-----VYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
+ L + +L K+ Q +K I+++ KS++ ++
Sbjct: 371 ESLQRVKSKLEKDKQVMKAEIDDLNASMETIQKSKMNAEAHVRKLEDSLSEANAKVAELE 430
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+Q EI+ R+Q E SE + E + N +I ++
Sbjct: 431 RNQAEINAIRTRLQ-AENSELSREYEESQSRLN-QILRIKTSLTSQVDDYKRQLDEESKS 488
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR-----ELQKRTE 372
S L +E+++ +SE++ L+ L T R + +RTE
Sbjct: 489 RSTAVVSLANTKHDLDLVKEQLEEEQGG-KSELQRLVSKLNTEVTTWRTKYETDAIQRTE 547
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
+LE ++ +RL+E + E Q + + QR+ E++
Sbjct: 548 ELEETKRKLAARLQEAEEAAETAQARAASLEKNKQRLQAEVE 589
Score = 37.1 bits (82), Expect = 0.15
Identities = 59/405 (14%), Positives = 150/405 (37%), Gaps = 7/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ K+R + DL + ++++EK L + + L+ E + N K T+
Sbjct: 163 LDHKVRTLTGDLSLREDSITKLQKEKRALEELHQKTLDDLQAEEDKVNHLTKNNSKLSTQ 222
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+ +L E E +K ++ + + ++++ ++K E+ K E+
Sbjct: 223 IHELEDNWEQEKKIRAEVEKARRKAESDLKMTI-DNLNEMERSKLDLEEVVKKRDLEINS 281
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ ++ E+ T+ + + + I EL ++E I +++R E ++L +E
Sbjct: 282 VNSKYEDEQSLNSTLQRKLKEHQDRIEELEEELEAERAMRAKIEQNRKR-EAELLKLRRE 340
Query: 216 VQDLKVNIE-NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++ + E L+ + ++ +++ + +E
Sbjct: 341 LEEAALQSEATASTLRKKHVDSMAELTEHVESLQRVKSKLEKDKQVMKAEIDDLNASMET 400
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
+++++ E + K + +K + +
Sbjct: 401 IQKSKMNAEAHVRKLEDSLSEANAK-VAELERNQAEINAIRTRLQAENSELSREYEESQS 459
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
++N + + K+ L S+V+ L++ + + + +K +LEE +
Sbjct: 460 RLNQILRIKTSLTSQVDDYKRQLDEESKSRSTAVVSLANTKHDLDLVKEQLEEEQGGKSE 519
Query: 395 TQRDLRNKQTELQ--RVSHELDKTREQKDALARENKKMGDDLHDA 437
QR + TE+ R +E D ++ + L +K+ L +A
Sbjct: 520 LQRLVSKLNTEVTTWRTKYETDAI-QRTEELEETKRKLAARLQEA 563
Score = 31.1 bits (67), Expect = 9.7
Identities = 20/98 (20%), Positives = 41/98 (41%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K +L+ E+ L DLE T + +K + L+ + L + Q++ R
Sbjct: 132 KRKLEGELSDLKRDLEGLETTLAKTEKEKQALDHKVRTLTGDLSLREDSITKLQKEKRAL 191
Query: 403 QTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
+ Q+ +L ++ + L + N K+ +H+ N
Sbjct: 192 EELHQKTLDDLQAEEDKVNHLTKNNSKLSTQIHELEDN 229
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 187 bits (456), Expect = 7e-47
Identities = 105/402 (26%), Positives = 205/402 (50%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ L+ +I+ +++ LE+ER R ++ERE+ADL+ + L+ERLEE G + +Q EI +K+
Sbjct: 1130 VKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQ 1189
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+T++ KL + +E+ L E T+ LKK++ + + + + Q++ L + K + EK+KS Q E
Sbjct: 1190 ETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLE 1249
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
V +LL +VE +T+ K K C E + E K++++ + D+ + K +L E+ E
Sbjct: 1250 VDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEF 1309
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
++ +++ + I + KS Q +L + + D + +R Q
Sbjct: 1310 LRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQY 1369
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
EEE E + +L R L K N E+ WR K+ + +
Sbjct: 1370 EEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVA 1429
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A+ ++E+ + +LQ E+ + DL K A L ++ Q + + K + EE+ L
Sbjct: 1430 NARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALL 1489
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ +Q++++ TEL ++ + +++ ++ L RENK + +++
Sbjct: 1490 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEI 1531
Score = 76.6 bits (180), Expect = 2e-13
Identities = 80/430 (18%), Positives = 162/430 (37%), Gaps = 7/430 (1%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQV 68
K TY S G + E +S L +++R +L ++++ IE EK ++ V
Sbjct: 1507 KNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVT- 1565
Query: 69 IQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDF 128
LEE EG E ELL+ + LE E +E ++K Q +
Sbjct: 1566 ------LEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSL 1619
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
Q +D K++ + K K + ++ E+ Q+ ++ +K+ +L+I I +L +++
Sbjct: 1620 QSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQL 1679
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
++ + D+ + N L E++DL+ E + +
Sbjct: 1680 DDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFY 1739
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
+ ++E D+ ++ + EE + + E + KA E + +
Sbjct: 1740 TQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIA 1799
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
+ KQ +L+S V L +LE + E Q
Sbjct: 1800 HLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQ 1859
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+ +LER E+ + EE + + Q + Q ++Q +++ Q + + K
Sbjct: 1860 RGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYK 1919
Query: 429 KMGDDLHDAR 438
K +L++ +
Sbjct: 1920 KQQHELNEVK 1929
Score = 61.7 bits (143), Expect = 6e-09
Identities = 98/478 (20%), Positives = 192/478 (40%), Gaps = 44/478 (9%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +++L+A R LED+ ++ +++ + + E+EK +V L+E +E E
Sbjct: 953 EINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLN---E 1009
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKAR 141
++NR ++ L+D+H+E E+ + L K K ++ V + + ++Q K +
Sbjct: 1010 DISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMN 1069
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+E K + + +EN+ + +++ + E+ +S+++ K+E +
Sbjct: 1070 CERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVE----------NE 1119
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
K ++Q L K V++L+ I++ LK ++ ++ A L Q
Sbjct: 1120 KGLVAQ----LQKTVKELQTQIKD---LKEKLEAERTTRAKMERER--------ADLTQD 1164
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
DL ++ S A+L++ + K +I +++
Sbjct: 1165 LADLNERLEEVGGSSLAQLEITK---KQETKIQKLHRDMEEATLHFETTSASLKKRHADS 1221
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
L +EK KS LQ EV+ L+ +E+ +K E E
Sbjct: 1222 LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1281
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA----LARENKKMGDDLHDA 437
++L++ QL DL ++T+L S E + E+K+A L+RE + D
Sbjct: 1282 TAKLDKVTQL----ANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDL 1337
Query: 438 RANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRS-QRLTAEFGQFR 494
R + Y+E E KAE R+ ++ AE Q+R
Sbjct: 1338 RGQLEKETKSQSALAHALQKAQRDCDLLREQYEE-EQEVKAELHRTLSKVNAEMVQWR 1394
Score = 60.9 bits (141), Expect = 1e-08
Identities = 96/504 (19%), Positives = 191/504 (37%), Gaps = 27/504 (5%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSR----LEDKIRLIQDDLESERELRQR 56
+S + + +K + D+++E LS+LS+ LE ++ ++ LE ER+ R
Sbjct: 1011 ISKLNRAAKVVQEAHQQTLDDLHME-EEKLSSLSKANLKLEQQVDELEGALEQERKARMN 1069
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL 116
ERE L + E +E E E RK++ EL ++ +E+ E A L
Sbjct: 1070 CERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVEN---EKGLVAQL 1126
Query: 117 LK--KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTC 174
K K+ Q + D +E+++ T+A+ E+E++ ++ +L ++E V + +
Sbjct: 1127 QKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEIT 1186
Query: 175 ERLEITISELHIKIEELNRTI-VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
++ E I +LH +EE S K+R + EL +V++L+ + + KS +
Sbjct: 1187 KKQETKIQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDL 1246
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ E L +L++ ++ DL Q K E
Sbjct: 1247 QLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSES 1306
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
G + + + S L ++ K +S L ++
Sbjct: 1307 GEFLRRL--------EEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKA 1358
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE----QTQRDLRNKQTE---- 405
D + E Q+ +L R ++ + + + YE Q DL + + E
Sbjct: 1359 QRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIR 1418
Query: 406 LQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXX 465
LQ + + + +L R ++ +L DA +++
Sbjct: 1419 LQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADW 1478
Query: 466 TAAYKEAEAGRKAEEQRSQRLTAE 489
++E++A A ++ Q L+ E
Sbjct: 1479 KQKHEESQALLDASQKEVQALSTE 1502
Score = 59.3 bits (137), Expect = 3e-08
Identities = 72/418 (17%), Positives = 172/418 (41%), Gaps = 20/418 (4%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
SA AL + + L+++ E E+E++ + R + ++ +++Q R++ +
Sbjct: 1349 SALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQW--RMKYENNVIQRTE 1406
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
++ + ++L++ E + + + A L + ++Q + ++ + + L K ++ A +
Sbjct: 1407 DLEDAKKELAIRLQEAAEAMGVANARNASLERARHQ-LQLELGDALSDLGKVRSAAARLD 1465
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
K Q + + LA + +E + ++ + L ++ +L T + ++ L
Sbjct: 1466 QK-QLQSGKALADWKQKHEESQALLDASQK---EVQALSTELLKLKNTYEESIVGQETLR 1521
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
+EN L +E+ +L + +++ +L + E +
Sbjct: 1522 RENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKIL 1581
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX---------- 316
+++L EA+ +LER+L + + EI ++R K
Sbjct: 1582 HFQLEL---LEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKK 1638
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
K +++ K +LQ +++ L + L+ + +L+++ ER
Sbjct: 1639 KMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAER 1698
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
N ++S LE+ L EQT+R R + EL + ++ Q +L + KK+ D+
Sbjct: 1699 RNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV 1756
Score = 50.0 bits (114), Expect = 2e-05
Identities = 88/447 (19%), Positives = 178/447 (39%), Gaps = 42/447 (9%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE---AEGGAESQFE 87
S R D + ++ +E+ ++++Q++E++K+DL ++V L R+E+ A+ AE
Sbjct: 1213 SLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCT 1272
Query: 88 INRKR----DTELLKLRKLLEDV-----HLESEETAHLLKKKNQEIVID--------FQE 130
+ +R +L K+ +L D+ L SE L + + +E +I+ F
Sbjct: 1273 LYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTR 1332
Query: 131 QIDQL-------TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE 183
QI+ L TK+++ K Q + L Q E + K + +T ++ + +
Sbjct: 1333 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQ 1392
Query: 184 LHIKIEE--LNRTIVDITSHKQRLSQENIELVKEVQDLKV-NIENVVYLKSQIASQXXXX 240
+K E + RT D+ K+ L+ I L + + + V N N +++ Q
Sbjct: 1393 WRMKYENNVIQRT-EDLEDAKKELA---IRLQEAAEAMGVANARNASLERAR--HQLQLE 1446
Query: 241 XXXXXXXXXXXXXXXASLHQVEIDLESVRV---QLEEESEARLDLERQLVKA-NGEIGHW 296
A L Q ++ Q EES+A LD ++ V+A + E+
Sbjct: 1447 LGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKL 1506
Query: 297 RSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIID 356
++ + + +EK K ++ E + +
Sbjct: 1507 KNTYEESIVGQETLRRENKNLQEEISNLTNQVREGT-KNLTEMEKVKKLIEEEKTEVQVT 1565
Query: 357 LEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQT-ELQRVSHELDK 415
LE+ G + + + +E K+ LE + ++ + R KQ + + LD
Sbjct: 1566 LEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDS 1625
Query: 416 TREQKDALARENKKMGDDLHDARANIT 442
+ + + R KKM +DL++ ++
Sbjct: 1626 EAKSRIEVTRLKKKMEEDLNEMELQLS 1652
Score = 44.4 bits (100), Expect = 0.001
Identities = 74/350 (21%), Positives = 143/350 (40%), Gaps = 25/350 (7%)
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+K ++ E+V EE A L K + +FQ + +L + +EK+ ++
Sbjct: 861 LVKSSEVGEEVAGLKEECAQLQKALEKS---EFQRE--ELKAKQVSLTQEKNDLILQLQA 915
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ NV ++ + K+ +LE + EL ++EE ++T+ ++L E EL KE
Sbjct: 916 EQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKE 975
Query: 216 VQDLKVNI------ENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI-DLESV 268
+ DL+ + + K + ++ HQ + DL
Sbjct: 976 IDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHME 1035
Query: 269 RVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
+L S+A L LE+Q+ + G + R K
Sbjct: 1036 EEKLSSLSKANLKLEQQVDELEGALEQER-KARMNCERELHKLEGNLKLNRESMENLESS 1094
Query: 329 XXTLIAKINNVEKQKSRLQSEVE---VLIIDLEKANGTARELQKRTEQL-ERVNIEIKSR 384
L ++ E + S++ S+VE L+ L+K T +ELQ + + L E++ E +R
Sbjct: 1095 QRHLAEELRKKELELSQMNSKVENEKGLVAQLQK---TVKELQTQIKDLKEKLEAERTTR 1151
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVS----HELDKTREQKDALARENKKM 430
+ + + TQ DL + L+ V +L+ T++Q+ + + ++ M
Sbjct: 1152 AKMERERADLTQ-DLADLNERLEEVGGSSLAQLEITKKQETKIQKLHRDM 1200
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 150 bits (363), Expect = 1e-35
Identities = 101/407 (24%), Positives = 185/407 (45%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E EL +V+ + + K +++E + EL +K E R ++ +L E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + S + SQ L QVE + S R
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QLEEE EA+ +LE+Q+ + ++ + K K
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM-EDSVGCLETAEEVKRKLQKDLEGLSQRH 1401
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+A + +EK K+RLQ E++ L++DL+ +A L+K+ ++ +++ E K+ +
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA 1461
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ ++ + + R K+T+ ++ L++ EQK L R NK+ ++ D
Sbjct: 1462 EERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/417 (17%), Positives = 166/417 (39%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 961 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ + + + +++E E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 74/407 (18%), Positives = 154/407 (37%), Gaps = 23/407 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT- 94
LE ++ ++ LE + Q E K L V + + + E G + Q E +K+
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED + A +KK + + D + ID K + A K+ K QA++
Sbjct: 1590 QVREMEAELEDER-KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ + ++++ + I + E + + ++ +L + K++ QE EL
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 215 EVQDLK----VNIENVVYLKSQIA---SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E+ + + +E L+++IA + + Q+ DL
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
R ++ AR LERQ N E+ KY
Sbjct: 1769 ERSHAQKNENARQQLERQ----NKEL----------KVKLQEMEGTVKSKYKASITALEA 1814
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L +++N K++ +V L+ + ++ EQ + + +RL++
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + + +++ EL+ E DA+ RE + + L
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 944 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 1063 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 1118
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/387 (14%), Positives = 155/387 (40%), Gaps = 2/387 (0%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + ++ +E+ K L + +L+ ++ G +K + +L +L+
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
+ E A + K E+ + + Q ++ K+ S ++++ + ++
Sbjct: 1261 FNEGERVRTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
++K+++S +++E + ++EE ++ L + ++ K+++D
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 223 IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
+E +K ++ + +++ +L+ + V L+ + ++ +L
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E++ K + + ++ K + + K +E+
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LERL 1498
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
+ ++E+E L+ + + EL+K LE+ E+K++LEE + T+
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 403 QTELQRVSHELDKTREQKDALARENKK 429
+ LQ + + ++ + +D + E KK
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 52.0 bits (119), Expect = 5e-06
Identities = 47/202 (23%), Positives = 92/202 (45%), Gaps = 6/202 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L ++R ++ +LE ER+ R + L + + L ++ A + + RK
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + L+D EE K+N++ + + ++ QL + A AE+ K + Q E
Sbjct: 1646 QMKDCMRELDDTRASREEIL-AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ N + + + RLE I++L ++EE I RL + N+++ +
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI---NDRLKKANLQIDQ 1761
Query: 215 EVQDLKVNIENVVYLKSQIASQ 236
DL N+E K++ A Q
Sbjct: 1762 INTDL--NLERSHAQKNENARQ 1781
Score = 46.4 bits (105), Expect = 2e-04
Identities = 83/463 (17%), Positives = 185/463 (39%), Gaps = 27/463 (5%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIERE 60
++ + KT + ++ ++ ++S + L+ ++ + ++ +LE + +Q +E E
Sbjct: 1169 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE---KAKQTLENE 1225
Query: 61 KADLSVQVIQLSERLEEAEGG---AESQFEINRKRDTELLKLRKLLED----VHLESEET 113
+ +L+ +V L + ++E E+Q + + + E ++R L D + +E +
Sbjct: 1226 RGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 114 AHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE---NVTKEK 167
LL + K+ ++ DF QL T+ ++E + + + L QVE N +E+
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ-KLSLSTKLKQVEDEKNSFREQ 1344
Query: 168 ITISKTCER-LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + + LE I+ LH ++ ++ + + D + + +L K+++ L E
Sbjct: 1345 LEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 1404
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
V ++ S +E + L EE +
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK------INNVE 340
+A E +K + +K ++ +E
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYEQTQRD 398
K K L+ +VE + LE+ + + +LE VN++ +K++ E +Q EQ++
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-VNLQAMKAQFERDLQGRDEQSEEK 1583
Query: 399 LRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/188 (20%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Query: 35 RLEDKIRLIQDDLESERELRQRI--EREKADLSVQVIQLSERLE--EAEGGAESQFEINR 90
RLE +I ++++LE E+ + I +KA+L + I LE A+ ++ ++ R
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ +KL+++ V + + + L+ K + +EQ+D TK + A K+ + +
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAK----IAQLEEQLDNETKERQAACKQVRRTE 1841
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
++ ++L QV++ + ++ + +L ++EE + +++L +E +
Sbjct: 1842 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE-L 1900
Query: 211 ELVKEVQD 218
E E D
Sbjct: 1901 EDATETAD 1908
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/198 (16%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV-------KLQ 1795
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 1796 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 1854
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
+ + + + K + +L Q+E +E + + +L+ + + + +NR
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR-- 1912
Query: 196 VDITSHKQRLSQENIELV 213
+++S K +L + ++ V
Sbjct: 1913 -EVSSLKNKLRRGDLPFV 1929
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 990
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 991 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 1050
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 1111 SQISELQEDL 1120
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE + + LQ +++++ E++ +LEE
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Score = 31.9 bits (69), Expect = 5.5
Identities = 16/85 (18%), Positives = 41/85 (48%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + + Q + +
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE 965
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 150 bits (363), Expect = 1e-35
Identities = 101/407 (24%), Positives = 185/407 (45%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E EL +V+ + + K +++E + EL +K E R ++ +L E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + S + SQ L QVE + S R
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QLEEE EA+ +LE+Q+ + ++ + K K
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM-EDSVGCLETAEEVKRKLQKDLEGLSQRH 1401
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+A + +EK K+RLQ E++ L++DL+ +A L+K+ ++ +++ E K+ +
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA 1461
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ ++ + + R K+T+ ++ L++ EQK L R NK+ ++ D
Sbjct: 1462 EERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/417 (17%), Positives = 166/417 (39%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 961 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ + + + +++E E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 74/407 (18%), Positives = 154/407 (37%), Gaps = 23/407 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT- 94
LE ++ ++ LE + Q E K L V + + + E G + Q E +K+
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED + A +KK + + D + ID K + A K+ K QA++
Sbjct: 1590 QVREMEAELEDER-KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ + ++++ + I + E + + ++ +L + K++ QE EL
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 215 EVQDLK----VNIENVVYLKSQIA---SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E+ + + +E L+++IA + + Q+ DL
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
R ++ AR LERQ N E+ KY
Sbjct: 1769 ERSHAQKNENARQQLERQ----NKEL----------KVKLQEMEGTVKSKYKASITALEA 1814
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L +++N K++ +V L+ + ++ EQ + + +RL++
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + + +++ EL+ E DA+ RE + + L
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 944 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 1063 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 1118
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/387 (14%), Positives = 155/387 (40%), Gaps = 2/387 (0%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + ++ +E+ K L + +L+ ++ G +K + +L +L+
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
+ E A + K E+ + + Q ++ K+ S ++++ + ++
Sbjct: 1261 FNEGERVRTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
++K+++S +++E + ++EE ++ L + ++ K+++D
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 223 IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
+E +K ++ + +++ +L+ + V L+ + ++ +L
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E++ K + + ++ K + + K +E+
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LERL 1498
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
+ ++E+E L+ + + EL+K LE+ E+K++LEE + T+
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 403 QTELQRVSHELDKTREQKDALARENKK 429
+ LQ + + ++ + +D + E KK
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 52.0 bits (119), Expect = 5e-06
Identities = 47/202 (23%), Positives = 92/202 (45%), Gaps = 6/202 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L ++R ++ +LE ER+ R + L + + L ++ A + + RK
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + L+D EE K+N++ + + ++ QL + A AE+ K + Q E
Sbjct: 1646 QMKDCMRELDDTRASREEIL-AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ N + + + RLE I++L ++EE I RL + N+++ +
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI---NDRLKKANLQIDQ 1761
Query: 215 EVQDLKVNIENVVYLKSQIASQ 236
DL N+E K++ A Q
Sbjct: 1762 INTDL--NLERSHAQKNENARQ 1781
Score = 46.4 bits (105), Expect = 2e-04
Identities = 83/463 (17%), Positives = 185/463 (39%), Gaps = 27/463 (5%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIERE 60
++ + KT + ++ ++ ++S + L+ ++ + ++ +LE + +Q +E E
Sbjct: 1169 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE---KAKQTLENE 1225
Query: 61 KADLSVQVIQLSERLEEAEGG---AESQFEINRKRDTELLKLRKLLED----VHLESEET 113
+ +L+ +V L + ++E E+Q + + + E ++R L D + +E +
Sbjct: 1226 RGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 114 AHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE---NVTKEK 167
LL + K+ ++ DF QL T+ ++E + + + L QVE N +E+
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ-KLSLSTKLKQVEDEKNSFREQ 1344
Query: 168 ITISKTCER-LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + + LE I+ LH ++ ++ + + D + + +L K+++ L E
Sbjct: 1345 LEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 1404
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
V ++ S +E + L EE +
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK------INNVE 340
+A E +K + +K ++ +E
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYEQTQRD 398
K K L+ +VE + LE+ + + +LE VN++ +K++ E +Q EQ++
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-VNLQAMKAQFERDLQGRDEQSEEK 1583
Query: 399 LRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/188 (20%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Query: 35 RLEDKIRLIQDDLESERELRQRI--EREKADLSVQVIQLSERLE--EAEGGAESQFEINR 90
RLE +I ++++LE E+ + I +KA+L + I LE A+ ++ ++ R
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ +KL+++ V + + + L+ K + +EQ+D TK + A K+ + +
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAK----IAQLEEQLDNETKERQAACKQVRRTE 1841
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
++ ++L QV++ + ++ + +L ++EE + +++L +E +
Sbjct: 1842 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE-L 1900
Query: 211 ELVKEVQD 218
E E D
Sbjct: 1901 EDATETAD 1908
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/198 (16%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV-------KLQ 1795
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 1796 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 1854
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
+ + + + K + +L Q+E +E + + +L+ + + + +NR
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR-- 1912
Query: 196 VDITSHKQRLSQENIELV 213
+++S K +L + ++ V
Sbjct: 1913 -EVSSLKNKLRRGDLPFV 1929
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 990
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 991 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 1050
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 1111 SQISELQEDL 1120
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE + + LQ +++++ E++ +LEE
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Score = 31.9 bits (69), Expect = 5.5
Identities = 16/85 (18%), Positives = 41/85 (48%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + + Q + +
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE 965
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 150 bits (363), Expect = 1e-35
Identities = 101/407 (24%), Positives = 185/407 (45%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E EL +V+ + + K +++E + EL +K E R ++ +L E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + S + SQ L QVE + S R
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QLEEE EA+ +LE+Q+ + ++ + K K
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKKM-EDSVGCLETAEEVKRKLQKDLEGLSQRH 1401
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+A + +EK K+RLQ E++ L++DL+ +A L+K+ ++ +++ E K+ +
Sbjct: 1402 EEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA 1461
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ ++ + + R K+T+ ++ L++ EQK L R NK+ ++ D
Sbjct: 1462 EERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/417 (17%), Positives = 166/417 (39%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 961 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ + + + +++E E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 58.8 bits (136), Expect = 4e-08
Identities = 74/407 (18%), Positives = 154/407 (37%), Gaps = 23/407 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT- 94
LE ++ ++ LE + Q E K L V + + + E G + Q E +K+
Sbjct: 1530 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 1589
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED + A +KK + + D + ID K + A K+ K QA++
Sbjct: 1590 QVREMEAELEDER-KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 1648
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ + ++++ + I + E + + ++ +L + K++ QE EL
Sbjct: 1649 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 215 EVQDLK----VNIENVVYLKSQIA---SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E+ + + +E L+++IA + + Q+ DL
Sbjct: 1709 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 1768
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
R ++ AR LERQ N E+ KY
Sbjct: 1769 ERSHAQKNENARQQLERQ----NKEL----------KVKLQEMEGTVKSKYKASITALEA 1814
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L +++N K++ +V L+ + ++ EQ + + +RL++
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + + +++ EL+ E DA+ RE + + L
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 944 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 1063 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 1118
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 56.4 bits (130), Expect = 2e-07
Identities = 56/387 (14%), Positives = 155/387 (40%), Gaps = 2/387 (0%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + ++ +E+ K L + +L+ ++ G +K + +L +L+
Sbjct: 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVK 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
+ E A + K E+ + + Q ++ K+ S ++++ + ++
Sbjct: 1261 FNEGERVRTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 1319
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
++K+++S +++E + ++EE ++ L + ++ K+++D
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 223 IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
+E +K ++ + +++ +L+ + V L+ + ++ +L
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E++ K + + ++ K + + K +E+
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LERL 1498
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
+ ++E+E L+ + + EL+K LE+ E+K++LEE + T+
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 403 QTELQRVSHELDKTREQKDALARENKK 429
+ LQ + + ++ + +D + E KK
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Score = 52.0 bits (119), Expect = 5e-06
Identities = 47/202 (23%), Positives = 92/202 (45%), Gaps = 6/202 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L ++R ++ +LE ER+ R + L + + L ++ A + + RK
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + L+D EE K+N++ + + ++ QL + A AE+ K + Q E
Sbjct: 1646 QMKDCMRELDDTRASREEIL-AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 1704
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ N + + + RLE I++L ++EE I RL + N+++ +
Sbjct: 1705 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI---NDRLKKANLQIDQ 1761
Query: 215 EVQDLKVNIENVVYLKSQIASQ 236
DL N+E K++ A Q
Sbjct: 1762 INTDL--NLERSHAQKNENARQ 1781
Score = 46.4 bits (105), Expect = 2e-04
Identities = 83/463 (17%), Positives = 185/463 (39%), Gaps = 27/463 (5%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIERE 60
++ + KT + ++ ++ ++S + L+ ++ + ++ +LE + +Q +E E
Sbjct: 1169 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE---KAKQTLENE 1225
Query: 61 KADLSVQVIQLSERLEEAEGG---AESQFEINRKRDTELLKLRKLLED----VHLESEET 113
+ +L+ +V L + ++E E+Q + + + E ++R L D + +E +
Sbjct: 1226 RGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 114 AHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE---NVTKEK 167
LL + K+ ++ DF QL T+ ++E + + + L QVE N +E+
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ-KLSLSTKLKQVEDEKNSFREQ 1344
Query: 168 ITISKTCER-LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + + LE I+ LH ++ ++ + + D + + +L K+++ L E
Sbjct: 1345 LEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEK 1404
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
V ++ S +E + L EE +
Sbjct: 1405 VAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEER 1464
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK------INNVE 340
+A E +K + +K ++ +E
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYEQTQRD 398
K K L+ +VE + LE+ + + +LE VN++ +K++ E +Q EQ++
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-VNLQAMKAQFERDLQGRDEQSEEK 1583
Query: 399 LRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1626
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/188 (20%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Query: 35 RLEDKIRLIQDDLESERELRQRI--EREKADLSVQVIQLSERLE--EAEGGAESQFEINR 90
RLE +I ++++LE E+ + I +KA+L + I LE A+ ++ ++ R
Sbjct: 1726 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1785
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ +KL+++ V + + + L+ K + +EQ+D TK + A K+ + +
Sbjct: 1786 QNKELKVKLQEMEGTVKSKYKASITALEAK----IAQLEEQLDNETKERQAACKQVRRTE 1841
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
++ ++L QV++ + ++ + +L ++EE + +++L +E +
Sbjct: 1842 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE-L 1900
Query: 211 ELVKEVQD 218
E E D
Sbjct: 1901 EDATETAD 1908
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/198 (16%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 1743 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV-------KLQ 1795
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 1796 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 1854
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
+ + + + K + +L Q+E +E + + +L+ + + + +NR
Sbjct: 1855 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR-- 1912
Query: 196 VDITSHKQRLSQENIELV 213
+++S K +L + ++ V
Sbjct: 1913 -EVSSLKNKLRRGDLPFV 1929
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 990
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 991 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 1050
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 1111 SQISELQEDL 1120
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE + + LQ +++++ E++ +LEE
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Score = 31.9 bits (69), Expect = 5.5
Identities = 16/85 (18%), Positives = 41/85 (48%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + + Q + +
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE 965
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 148 bits (358), Expect = 5e-35
Identities = 98/420 (23%), Positives = 195/420 (46%), Gaps = 9/420 (2%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D + + L + L+ +I +Q+D ESE+ R + E++K DLS ++ L LE+
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+Q E+ KR+ E+ +L+K LE+ E +++++ + + EQ++Q + KA
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
EK K + + EL +V+ + + K ++L+ + ELH K+ E +R V++
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 201 HKQRLSQE--NIELVKEVQDLKVNIENVVYLK--SQIASQXXXXXXXXXXXXXXXXXXXA 256
+L E N+ + E + K + + K + + SQ +
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKK----GIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ Q+E + S++ Q EEE EAR +LE+Q++ ++ + K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+A + +EK K+RLQ E++ L +DL+ A L+K+ ++ ++
Sbjct: 1397 LLKDAEALSQRLEEKALA-YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E KS + ++ + + R K+T+ ++ L++ E K+ R+NK++ D+ D
Sbjct: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/405 (17%), Positives = 168/405 (41%), Gaps = 7/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+K ++ + L++E EL E +A L+ + +L E L + E E + E N+ E
Sbjct: 886 LEEK-NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
Query: 96 LLKLRKLLEDVH--LESEETAHL---LKKKNQEIVID-FQEQIDQLTKTKARAEKEKSKF 149
K++ ++D+ L+ EE A L+K E I +E+I L ++ KEK
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ + E +Q+ ++ ++K + E+ IS+L ++++ +T ++ K++L E
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+L ++ +L+ I+ + ++ + + +++ + ++
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
E E +R E+Q + E+ +++ +
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ + R + +E L LE+A L+K + LE N E+ ++
Sbjct: 1185 EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
Q+ +++ + ++Q + ++ + + LA + K+ ++L
Sbjct: 1245 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/448 (18%), Positives = 174/448 (38%), Gaps = 11/448 (2%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGG-AESQFEINRKRDT-----EL-LKLRKLLE 104
+L+ +I +A + +QL+++ EE +G A E K + EL ++ +L E
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 105 DVHLE--SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
D E S A K+ E + + +++ T A ++ ++K + EV EL +E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 163 VTKE-KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
TK + I +R + EL ++E+ R ++ +KQ L +N EL EV+ L+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
+ + ++ +Q +++ +L++V LEE + +
Sbjct: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
+ ++ + A+ N+EK
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR-KNLEK 1364
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q LQS++ ++ GT L++ ++L + + RLEE Y++ ++
Sbjct: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
Q EL ++ +LD R+ L ++ KK L + ++
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
A +EA ++ E+++++L A+
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRAD 1512
Score = 67.3 bits (157), Expect = 1e-10
Identities = 69/395 (17%), Positives = 160/395 (40%), Gaps = 16/395 (4%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + + +E+ K L +L+ ++ + +++ E RK KL
Sbjct: 1208 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ-VKAESEHKRK------KLDAQ 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
++++H + E L+ + E Q ++D ++ AEK+ KF + L +Q+++
Sbjct: 1261 VQELHAKVSE-GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 163 V-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
T++K+ +S +LE + L + EE ++ L + + K+
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
V D IE++ K ++ + ++++ +L+ + V L+ +
Sbjct: 1380 VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQ 1439
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ +LE++ K + + +S K + L AK
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E+Q +L++++E L+ + EL+K LE+ E++++LEE + T
Sbjct: 1500 -EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +Q + + ++ + +D E K++
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 26/423 (6%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLE-SERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
N + AD+ L +D + +LE S+R L Q++E ++ Q+ +L + L+ E
Sbjct: 1506 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE----EMRTQLEELEDELQATED- 1560
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
A+ + E+N + + + L+ ++EE LL K+ +E+ + +++ K +A
Sbjct: 1561 AKLRLEVNMQ--AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE----RKQRAL 1614
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A K K + ++ +L AQ+E K + + K +L+ + + ++EE + +I +
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1674
Query: 202 KQR-------LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ L E ++L +E+ + + + ++A +
Sbjct: 1675 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1734
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
A + Q+E +LE + +E ++ Q+ N E+ RS
Sbjct: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1794
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ A I+ +E + +L+ ++E K A +L +RTE+
Sbjct: 1795 KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE----QEAKERAAANKLVRRTEKK 1850
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ EI ++E+ + +Q + + ++++ +L++ E+ +K+ +L
Sbjct: 1851 LK---EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 435 HDA 437
DA
Sbjct: 1908 DDA 1910
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 148 bits (358), Expect = 5e-35
Identities = 98/420 (23%), Positives = 195/420 (46%), Gaps = 9/420 (2%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D + + L + L+ +I +Q+D ESE+ R + E++K DLS ++ L LE+
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+Q E+ KR+ E+ +L+K LE+ E +++++ + + EQ++Q + KA
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
EK K + + EL +V+ + + K ++L+ + ELH K+ E +R V++
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 201 HKQRLSQE--NIELVKEVQDLKVNIENVVYLK--SQIASQXXXXXXXXXXXXXXXXXXXA 256
+L E N+ + E + K + + K + + SQ +
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKK----GIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ Q+E + S++ Q EEE EAR +LE+Q++ ++ + K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+A + +EK K+RLQ E++ L +DL+ A L+K+ ++ ++
Sbjct: 1397 LLKDAEALSQRLEEKALA-YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E KS + ++ + + R K+T+ ++ L++ E K+ R+NK++ D+ D
Sbjct: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/405 (17%), Positives = 168/405 (41%), Gaps = 7/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+K ++ + L++E EL E +A L+ + +L E L + E E + E N+ E
Sbjct: 886 LEEK-NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
Query: 96 LLKLRKLLEDVH--LESEETAHL---LKKKNQEIVID-FQEQIDQLTKTKARAEKEKSKF 149
K++ ++D+ L+ EE A L+K E I +E+I L ++ KEK
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ + E +Q+ ++ ++K + E+ IS+L ++++ +T ++ K++L E
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+L ++ +L+ I+ + ++ + + +++ + ++
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
E E +R E+Q + E+ +++ +
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ + R + +E L LE+A L+K + LE N E+ ++
Sbjct: 1185 EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
Q+ +++ + ++Q + ++ + + LA + K+ ++L
Sbjct: 1245 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/448 (18%), Positives = 174/448 (38%), Gaps = 11/448 (2%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGG-AESQFEINRKRDT-----EL-LKLRKLLE 104
+L+ +I +A + +QL+++ EE +G A E K + EL ++ +L E
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 105 DVHLE--SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
D E S A K+ E + + +++ T A ++ ++K + EV EL +E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 163 VTKE-KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
TK + I +R + EL ++E+ R ++ +KQ L +N EL EV+ L+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
+ + ++ +Q +++ +L++V LEE + +
Sbjct: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
+ ++ + A+ N+EK
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR-KNLEK 1364
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q LQS++ ++ GT L++ ++L + + RLEE Y++ ++
Sbjct: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
Q EL ++ +LD R+ L ++ KK L + ++
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
A +EA ++ E+++++L A+
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRAD 1512
Score = 67.3 bits (157), Expect = 1e-10
Identities = 69/395 (17%), Positives = 160/395 (40%), Gaps = 16/395 (4%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + + +E+ K L +L+ ++ + +++ E RK KL
Sbjct: 1208 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ-VKAESEHKRK------KLDAQ 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
++++H + E L+ + E Q ++D ++ AEK+ KF + L +Q+++
Sbjct: 1261 VQELHAKVSE-GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 163 V-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
T++K+ +S +LE + L + EE ++ L + + K+
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
V D IE++ K ++ + ++++ +L+ + V L+ +
Sbjct: 1380 VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQ 1439
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ +LE++ K + + +S K + L AK
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E+Q +L++++E L+ + EL+K LE+ E++++LEE + T
Sbjct: 1500 -EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +Q + + ++ + +D E K++
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 26/423 (6%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLE-SERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
N + AD+ L +D + +LE S+R L Q++E ++ Q+ +L + L+ E
Sbjct: 1506 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE----EMRTQLEELEDELQATED- 1560
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
A+ + E+N + + + L+ ++EE LL K+ +E+ + +++ K +A
Sbjct: 1561 AKLRLEVNMQ--AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE----RKQRAL 1614
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A K K + ++ +L AQ+E K + + K +L+ + + ++EE + +I +
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1674
Query: 202 KQR-------LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ L E ++L +E+ + + + ++A +
Sbjct: 1675 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1734
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
A + Q+E +LE + +E ++ Q+ N E+ RS
Sbjct: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1794
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ A I+ +E + +L+ ++E K A +L +RTE+
Sbjct: 1795 KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE----QEAKERAAANKLVRRTEKK 1850
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ EI ++E+ + +Q + + ++++ +L++ E+ +K+ +L
Sbjct: 1851 LK---EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 435 HDA 437
DA
Sbjct: 1908 DDA 1910
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 148 bits (358), Expect = 5e-35
Identities = 98/420 (23%), Positives = 195/420 (46%), Gaps = 9/420 (2%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D + + L + L+ +I +Q+D ESE+ R + E++K DLS ++ L LE+
Sbjct: 1143 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1202
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+Q E+ KR+ E+ +L+K LE+ E +++++ + + EQ++Q + KA
Sbjct: 1203 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1262
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
EK K + + EL +V+ + + K ++L+ + ELH K+ E +R V++
Sbjct: 1263 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1322
Query: 201 HKQRLSQE--NIELVKEVQDLKVNIENVVYLK--SQIASQXXXXXXXXXXXXXXXXXXXA 256
+L E N+ + E + K + + K + + SQ +
Sbjct: 1323 KASKLQNELDNVSTLLEEAEKK----GIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1378
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ Q+E + S++ Q EEE EAR +LE+Q++ ++ + K
Sbjct: 1379 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1438
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+A + +EK K+RLQ E++ L +DL+ A L+K+ ++ ++
Sbjct: 1439 LLKDAEALSQRLEEKALA-YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQ 1497
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E KS + ++ + + R K+T+ ++ L++ E K+ R+NK++ D+ D
Sbjct: 1498 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1557
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/405 (17%), Positives = 168/405 (41%), Gaps = 7/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+K ++ + L++E EL E +A L+ + +L E L + E E + E N+ E
Sbjct: 928 LEEK-NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 986
Query: 96 LLKLRKLLEDVH--LESEETAHL---LKKKNQEIVID-FQEQIDQLTKTKARAEKEKSKF 149
K++ ++D+ L+ EE A L+K E I +E+I L ++ KEK
Sbjct: 987 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1046
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ + E +Q+ ++ ++K + E+ IS+L ++++ +T ++ K++L E
Sbjct: 1047 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1106
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+L ++ +L+ I+ + ++ + + +++ + ++
Sbjct: 1107 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1166
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
E E +R E+Q + E+ +++ +
Sbjct: 1167 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1226
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ + R + +E L LE+A L+K + LE N E+ ++
Sbjct: 1227 EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1286
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
Q+ +++ + ++Q + ++ + + LA + K+ ++L
Sbjct: 1287 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1331
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/448 (18%), Positives = 174/448 (38%), Gaps = 11/448 (2%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGG-AESQFEINRKRDT-----EL-LKLRKLLE 104
+L+ +I +A + +QL+++ EE +G A E K + EL ++ +L E
Sbjct: 1108 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1167
Query: 105 DVHLE--SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
D E S A K+ E + + +++ T A ++ ++K + EV EL +E
Sbjct: 1168 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1227
Query: 163 VTKE-KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
TK + I +R + EL ++E+ R ++ +KQ L +N EL EV+ L+
Sbjct: 1228 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1287
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
+ + ++ +Q +++ +L++V LEE + +
Sbjct: 1288 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1347
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
+ ++ + A+ N+EK
Sbjct: 1348 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR-KNLEK 1406
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q LQS++ ++ GT L++ ++L + + RLEE Y++ ++
Sbjct: 1407 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1466
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
Q EL ++ +LD R+ L ++ KK L + ++
Sbjct: 1467 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1526
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
A +EA ++ E+++++L A+
Sbjct: 1527 ALSLARALEEALEAKEEFERQNKQLRAD 1554
Score = 67.3 bits (157), Expect = 1e-10
Identities = 69/395 (17%), Positives = 160/395 (40%), Gaps = 16/395 (4%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + + +E+ K L +L+ ++ + +++ E RK KL
Sbjct: 1250 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ-VKAESEHKRK------KLDAQ 1302
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
++++H + E L+ + E Q ++D ++ AEK+ KF + L +Q+++
Sbjct: 1303 VQELHAKVSE-GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1361
Query: 163 V-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
T++K+ +S +LE + L + EE ++ L + + K+
Sbjct: 1362 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1421
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
V D IE++ K ++ + ++++ +L+ + V L+ +
Sbjct: 1422 VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQ 1481
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ +LE++ K + + +S K + L AK
Sbjct: 1482 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1541
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E+Q +L++++E L+ + EL+K LE+ E++++LEE + T
Sbjct: 1542 -EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1600
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +Q + + ++ + +D E K++
Sbjct: 1601 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1635
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 26/423 (6%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLE-SERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
N + AD+ L +D + +LE S+R L Q++E ++ Q+ +L + L+ E
Sbjct: 1548 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE----EMRTQLEELEDELQATED- 1602
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
A+ + E+N + + + L+ ++EE LL K+ +E+ + +++ K +A
Sbjct: 1603 AKLRLEVNMQ--AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE----RKQRAL 1656
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A K K + ++ +L AQ+E K + + K +L+ + + ++EE + +I +
Sbjct: 1657 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1716
Query: 202 KQR-------LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ L E ++L +E+ + + + ++A +
Sbjct: 1717 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1776
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
A + Q+E +LE + +E ++ Q+ N E+ RS
Sbjct: 1777 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1836
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ A I+ +E + +L+ ++E K A +L +RTE+
Sbjct: 1837 KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE----QEAKERAAANKLVRRTEKK 1892
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ EI ++E+ + +Q + + ++++ +L++ E+ +K+ +L
Sbjct: 1893 LK---EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1949
Query: 435 HDA 437
DA
Sbjct: 1950 DDA 1952
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 147 bits (355), Expect = 1e-34
Identities = 98/420 (23%), Positives = 194/420 (46%), Gaps = 9/420 (2%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D + + L + L+ +I +Q+D ESE+ R + E++K DLS ++ L LE+
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+Q E+ KR+ E+ +L+K LE+ E +++++ + + EQ++Q + KA
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKA 1220
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
EK K + + EL +V+ + + K ++L+ + ELH K+ E +R V++
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 201 HKQRLSQE--NIELVKEVQDLKVNIENVVYLK--SQIASQXXXXXXXXXXXXXXXXXXXA 256
+L E N+ + E + K + + K + + SQ +
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKK----GIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ Q+E + S++ Q EEE EAR +LE+Q++ ++ + K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKK 1396
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+A + +EK K+RLQ E + L +DL+ A L+K+ ++ ++
Sbjct: 1397 LLKDAEALSQRLEEKALA-YDKLEKTKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQ 1455
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E KS + ++ + + R K+T+ ++ L++ E K+ R+NK++ D+ D
Sbjct: 1456 LLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMED 1515
Score = 76.2 bits (179), Expect = 3e-13
Identities = 72/405 (17%), Positives = 168/405 (41%), Gaps = 7/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+K ++ + L++E EL E +A L+ + +L E L + E E + E N+ E
Sbjct: 886 LEEK-NILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNE 944
Query: 96 LLKLRKLLEDVH--LESEETAHL---LKKKNQEIVID-FQEQIDQLTKTKARAEKEKSKF 149
K++ ++D+ L+ EE A L+K E I +E+I L ++ KEK
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLM 1004
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ + E +Q+ ++ ++K + E+ IS+L ++++ +T ++ K++L E
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+L ++ +L+ I+ + ++ + + +++ + ++
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
E E +R E+Q + E+ +++ +
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ + R + +E L LE+A L+K + LE N E+ ++
Sbjct: 1185 EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQ 1244
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
Q+ +++ + ++Q + ++ + + LA + K+ ++L
Sbjct: 1245 QVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNEL 1289
Score = 66.1 bits (154), Expect = 3e-10
Identities = 84/448 (18%), Positives = 173/448 (38%), Gaps = 11/448 (2%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGG-AESQFEINRKRDT-----EL-LKLRKLLE 104
+L+ +I +A + +QL+++ EE +G A E K + EL ++ +L E
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 105 DVHLE--SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
D E S A K+ E + + +++ T A ++ ++K + EV EL +E
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 163 VTKE-KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
TK + I +R + EL ++E+ R ++ +KQ L +N EL EV+ L+
Sbjct: 1186 ETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ 1245
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
+ + ++ +Q +++ +L++V LEE + +
Sbjct: 1246 VKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK 1305
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
+ ++ + A+ N+EK
Sbjct: 1306 FAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR-KNLEK 1364
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q LQS++ ++ GT L++ ++L + + RLEE Y++ ++
Sbjct: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
Q E ++ +LD R+ L ++ KK L + ++
Sbjct: 1425 LQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETK 1484
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
A +EA ++ E+++++L A+
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRAD 1512
Score = 64.5 bits (150), Expect = 8e-10
Identities = 68/395 (17%), Positives = 159/395 (40%), Gaps = 16/395 (4%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+ + LE + + +E+ K L +L+ ++ + +++ E RK KL
Sbjct: 1208 LSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQ-VKAESEHKRK------KLDAQ 1260
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
++++H + E L+ + E Q ++D ++ AEK+ KF + L +Q+++
Sbjct: 1261 VQELHAKVSE-GDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 163 V-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
T++K+ +S +LE + L + EE ++ L + + K+
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
V D IE++ K ++ + ++++ + + + V L+ +
Sbjct: 1380 VDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQ 1439
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ +LE++ K + + +S K + L AK
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAK 1499
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E+Q +L++++E L+ + EL+K LE+ E++++LEE + T
Sbjct: 1500 -EEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +Q + + ++ + +D E K++
Sbjct: 1559 EDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 26/423 (6%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLE-SERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
N + AD+ L +D + +LE S+R L Q++E ++ Q+ +L + L+ E
Sbjct: 1506 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE----EMRTQLEELEDELQATED- 1560
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
A+ + E+N + + + L+ ++EE LL K+ +E+ + +++ K +A
Sbjct: 1561 AKLRLEVNMQ--AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE----RKQRAL 1614
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A K K + ++ +L AQ+E K + + K +L+ + + ++EE + +I +
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1674
Query: 202 KQR-------LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ L E ++L +E+ + + + ++A +
Sbjct: 1675 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 1734
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
A + Q+E +LE + +E ++ Q+ N E+ RS
Sbjct: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1794
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ A I+ +E + +L+ ++E K A +L +RTE+
Sbjct: 1795 KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE----QEAKERAAANKLVRRTEKK 1850
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ EI ++E+ + +Q + + ++++ +L++ E+ +K+ +L
Sbjct: 1851 LK---EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 435 HDA 437
DA
Sbjct: 1908 DDA 1910
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 143 bits (346), Expect = 2e-33
Identities = 100/408 (24%), Positives = 184/408 (45%), Gaps = 2/408 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 389 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 448
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 449 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 508
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E EL +V+ + + +++E + EL +K E R ++ +L E
Sbjct: 509 ENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 568
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + S + SQ L QVE + S R
Sbjct: 569 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 628
Query: 270 VQL-EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
QL EEE EA+ +LE+Q+ + ++ + K K
Sbjct: 629 EQLEEEEEEAKHNLEKQIATLHAQVADMKKKM-EDSVGCLETAEEVKRKLQKDLEGLSQR 687
Query: 329 XXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEET 388
+A + +EK K+RLQ E++ L++DL+ +A L+K+ ++ +++ E K+ +
Sbjct: 688 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKY 747
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ ++ + + R K+T+ ++ L++ EQK L R NK+ ++ D
Sbjct: 748 AEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 795
Score = 73.3 bits (172), Expect = 2e-12
Identities = 74/417 (17%), Positives = 167/417 (40%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 187 ELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQ 246
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 247 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 303
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 304 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 363
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 364 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 423
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 424 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 483
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ R+ + + +++E E+
Sbjct: 484 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQEL 543
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 544 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 600
Score = 58.4 bits (135), Expect = 6e-08
Identities = 74/407 (18%), Positives = 154/407 (37%), Gaps = 23/407 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT- 94
LE ++ ++ LE + Q E K L V + + + E G + Q E +K+
Sbjct: 817 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 876
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED + A +KK + + D + ID K + A K+ K QA++
Sbjct: 877 QVREMEAELEDER-KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 935
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ + ++++ + I + E + + ++ +L + K++ QE EL
Sbjct: 936 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 995
Query: 215 EVQDLK----VNIENVVYLKSQIA---SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E+ + + +E L+++IA + + Q+ DL
Sbjct: 996 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNL 1055
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
R ++ AR LERQ N E+ KY
Sbjct: 1056 ERGHAQKNENARQQLERQ----NKEL----------KVKLQEMEGTVKSKYKASITALEA 1101
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L +++N K++ +V L+ + ++ EQ + + +RL++
Sbjct: 1102 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1161
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + + +++ EL+ E DA+ RE + + L
Sbjct: 1162 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1208
Score = 56.8 bits (131), Expect = 2e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 170 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQ 229
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 230 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 288
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 289 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 348
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 349 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 404
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 405 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 464
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 465 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 524
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 525 GGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 568
Score = 56.4 bits (130), Expect = 2e-07
Identities = 85/394 (21%), Positives = 151/394 (38%), Gaps = 38/394 (9%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LED+I +L E E + + + K + L ERL E K+ E
Sbjct: 283 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE-----------KQRQE 331
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L K R+ LE +S + + + + + Q QI +L K + K++ + QA
Sbjct: 332 LEKTRRKLEG---DSTDLS--------DQIAELQAQIAEL---KMQLAKKEEELQA---- 373
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
LA+VE +K K LE ISEL +E + K+ L +E L E
Sbjct: 374 ALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTE 433
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE 274
++D + L+S+ + + Q +E + QLE+
Sbjct: 434 LEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQ 493
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
+ +LE KA + + R + K L
Sbjct: 494 TKRVKANLE----KAKQTLENERGELANEVKVLLQGGRDSEHK----RKKVEAQLQELQV 545
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K N E+ ++ L +V L ++L+ G + ++ +L + ++S+L++T +L ++
Sbjct: 546 KFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQE 605
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
R + T+L++V E + REQ + E K
Sbjct: 606 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAK 639
Score = 55.6 bits (128), Expect = 4e-07
Identities = 58/389 (14%), Positives = 161/389 (41%), Gaps = 5/389 (1%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEA-EGGAESQFEINRKRDTELLKLRK 101
+ + LE + ++ +E+ K L + +L+ ++ +GG +S+ + +K + +L +L+
Sbjct: 487 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHK-RKKVEAQLQELQV 545
Query: 102 LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE 161
+ E A + K E+ + + Q ++ K+ S ++++ + ++
Sbjct: 546 KFNEGERVRTELADKVTKLQVELD-NVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQ 604
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIV-DITSHKQRLSQENIELVKEVQDLK 220
++K+++S +++E + ++EE ++ L + ++ K+++D
Sbjct: 605 EENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADMKKKMEDSV 664
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
+E +K ++ + +++ +L+ + V L+ + ++
Sbjct: 665 GCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC 724
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
+LE++ K + + ++ K + + K +E
Sbjct: 725 NLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LE 783
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + ++E+E L+ + + EL+K LE+ E+K++LEE + T+
Sbjct: 784 RLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKL 843
Query: 401 NKQTELQRVSHELDKTREQKDALARENKK 429
+ LQ + + ++ + +D + E KK
Sbjct: 844 RLEVNLQAMKAQFERDLQGRDEQSEEKKK 872
Score = 51.6 bits (118), Expect = 6e-06
Identities = 47/202 (23%), Positives = 92/202 (45%), Gaps = 6/202 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L ++R ++ +LE ER+ R + L + + L ++ A + + RK
Sbjct: 873 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 932
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + L+D EE K+N++ + + ++ QL + A AE+ K + Q E
Sbjct: 933 QMKDCMRELDDTRASREEIL-AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 991
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ N + + + RLE I++L ++EE I RL + N+++ +
Sbjct: 992 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI---NDRLKKANLQIDQ 1048
Query: 215 EVQDLKVNIENVVYLKSQIASQ 236
DL N+E K++ A Q
Sbjct: 1049 INADL--NLERGHAQKNENARQ 1068
Score = 46.0 bits (104), Expect = 3e-04
Identities = 35/186 (18%), Positives = 89/186 (47%), Gaps = 5/186 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + I ++Q+ Q++ L G A+ ++ +
Sbjct: 1013 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLER 1072
Query: 95 ELLKLRKLLEDVH--LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ +L+ L+++ ++S+ A + + + + +EQ+D TK + A K+ + + +
Sbjct: 1073 QNKELKVKLQEMEGTVKSKYKASITALEAK--IAQLEEQLDNETKERQAACKQVRRTEKK 1130
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+ ++L QV++ + ++ + +L ++EE + +++L +E +E
Sbjct: 1131 LKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE-LED 1189
Query: 213 VKEVQD 218
E D
Sbjct: 1190 ATETAD 1195
Score = 45.2 bits (102), Expect = 6e-04
Identities = 83/464 (17%), Positives = 182/464 (39%), Gaps = 28/464 (6%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIERE 60
++ + KT + ++ ++ ++S + L+ ++ + ++ +LE + +Q +E E
Sbjct: 455 VNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE---KAKQTLENE 511
Query: 61 KADLSVQV---IQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED----VHLESEET 113
+ +L+ +V +Q E E+Q + + + E ++R L D + +E +
Sbjct: 512 RGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 571
Query: 114 AHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE---NVTKEK 167
LL + K+ ++ DF QL T+ ++E + + + L QVE N +E+
Sbjct: 572 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ-KLSLSTKLKQVEDEKNSFREQ 630
Query: 168 ITISK--TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+ + LE I+ LH ++ ++ + + D + + +L K+++ L E
Sbjct: 631 LEEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEE 690
Query: 226 VVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQ 285
V ++ S +E + L EE +
Sbjct: 691 KVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEE 750
Query: 286 LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK------INNV 339
+A E +K + +K ++ +
Sbjct: 751 RDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 810
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYEQTQR 397
EK K L+ +VE + LE+ + + +LE VN++ +K++ E +Q EQ++
Sbjct: 811 EKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-VNLQAMKAQFERDLQGRDEQSEE 869
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 870 KKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 913
Score = 37.5 bits (83), Expect = 0.11
Identities = 33/198 (16%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 1030 GNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKELKV-------KLQ 1082
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 1083 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 1141
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
+ + + + K + +L Q+E +E + + +L+ + + + +NR
Sbjct: 1142 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR-- 1199
Query: 196 VDITSHKQRLSQENIELV 213
+++S K +L + ++ V
Sbjct: 1200 -EVSSLKNKLRRGDLPFV 1216
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 222 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 276
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 277 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 336
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 337 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 396
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 397 SQISELQEDL 406
Score = 35.5 bits (78), Expect = 0.45
Identities = 17/85 (20%), Positives = 42/85 (49%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + Y+ Q + +
Sbjct: 167 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKK 226
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 227 MQQNIQELEEQLEEEESARQKLQLE 251
Score = 33.5 bits (73), Expect = 1.8
Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE----LQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE E LQ +++++ E++ +LEE
Sbjct: 181 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEE 240
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 241 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 295
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 19 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 78
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 79 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 138
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 139 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 198
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 199 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 258
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 259 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 317
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 318 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 377
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 378 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 424
Score = 68.1 bits (159), Expect = 7e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 305 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 363
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 364 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 423
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 424 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 482
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 483 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 542
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 543 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 601
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 602 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 661
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 662 EAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAVKSKF 721
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 722 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 760
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 135 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 187
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 188 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 246
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 247 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 306
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 307 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 366
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 367 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 425
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 426 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 485
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 486 ERDLQARDEQNEEKRRQLQRQLHE 509
Score = 55.6 bits (128), Expect = 4e-07
Identities = 83/417 (19%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 446 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 505
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 506 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 564
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 565 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 624
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 625 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 681
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ +R LERQ N E+ RSK K+
Sbjct: 682 LATERSTAQKNESSRQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 722
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 723 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 780
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 781 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 837
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/178 (22%), Positives = 81/178 (45%), Gaps = 8/178 (4%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQFEINR 90
RLE +I ++++LE E+ + + + Q QLS L A+ S+ ++ R
Sbjct: 642 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQLER 701
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ KL ++ V + + T L+ K + +EQ++Q + K A K +
Sbjct: 702 QNKELRSKLHEMEGAVKSKFKSTIAALEAK----IAQLEEQVEQEAREKQAATKSLKQKD 757
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 758 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 815
Score = 39.1 bits (87), Expect = 0.037
Identities = 33/145 (22%), Positives = 52/145 (35%)
Query: 345 RLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQT 404
+LQ+EVE + L +A G A +L K L + + L+E + LR +
Sbjct: 193 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 252
Query: 405 ELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXX 464
E + +LD+ E K L R + L D++ +
Sbjct: 253 ERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 312
Query: 465 XTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 313 LTQQYEEKAAAYDKLEKTKNRLQQE 337
Score = 34.7 bits (76), Expect = 0.79
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 2/98 (2%)
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
IA+ NN K+ L+ + L DL+ + +K+ L +K+ LE+T+
Sbjct: 12 IAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD-S 70
Query: 393 EQTQRDLRNK-QTELQRVSHELDKTREQKDALARENKK 429
TQ++LR K + E+ + LD+ +A +E ++
Sbjct: 71 TATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 108
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 745 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 804
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 805 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 842
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 723 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 782
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 783 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 816
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 224 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 283
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 284 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 343
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 344 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 403
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 404 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 463
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 464 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 522
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 523 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 582
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 583 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 629
Score = 75.4 bits (177), Expect = 5e-13
Identities = 66/405 (16%), Positives = 163/405 (40%), Gaps = 5/405 (1%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE+ + ++ LE E + Q+++ E+ ++ Q++ L E+LEE E + ++ ++ T
Sbjct: 34 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ---KLQLEKVTA 90
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
K++KL +++ + ++ L K++ +E + D + + + K K+K ++ +
Sbjct: 91 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 150
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
EL +++ K + + K +LE S+ H +I +L I ++ + +E +
Sbjct: 151 SELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAAL 210
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+ D N + ++ + +LE+++ +LE
Sbjct: 211 ARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE 270
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+ ++ + K E+ + K++
Sbjct: 271 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFK 330
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
N++K K L+ E L +L +E++ + ++LE E++S+ + +
Sbjct: 331 RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARA 390
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + Q E++ V+ L++ + LA++ + L D +
Sbjct: 391 ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ 435
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 91 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 150
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 151 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 209
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 210 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 269
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 270 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 329
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 330 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 389
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 390 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 445
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 446 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 505
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 506 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 542
Score = 67.3 bits (157), Expect = 1e-10
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 510 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 568
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 569 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 628
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 629 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRL-EVNMQALK 687
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 688 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQA 747
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 748 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 806
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 807 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 866
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 867 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 926
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 927 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 965
Score = 65.7 bits (153), Expect = 4e-10
Identities = 76/403 (18%), Positives = 166/403 (41%), Gaps = 25/403 (6%)
Query: 42 LIQDDLESEREL-------RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
L+Q+ L++E EL R R+ +K +L + ++ RLEE E + +K
Sbjct: 5 LLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 64
Query: 95 ELLKLRKLLEDVH-----LESEE-TAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++L L + LE+ L+ E+ TA KK ++ ++ +Q ++L+K + E+ S
Sbjct: 65 QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISD 124
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E + +N+TK K + E ISEL +++++ ++ ++ K++L +
Sbjct: 125 LTTNLAEEEEKAKNLTKLK-------NKHESMISELEVRLKKEEKSRQELEKLKRKLEGD 177
Query: 209 NIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
+ +++ DL+ I + ++ + + ++E + +
Sbjct: 178 ASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDL 237
Query: 269 RVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
+ L+ E AR E+Q E+ +++ +
Sbjct: 238 QEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKAL 297
Query: 329 XXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEET 388
+ V++ + + VE L LE+ L K + LE+ N ++ L
Sbjct: 298 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGEL--- 354
Query: 389 VQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALARENKKM 430
++ Q ++++ +K+ +L+ EL K + + A A N K+
Sbjct: 355 -RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKV 396
Score = 58.0 bits (134), Expect = 7e-08
Identities = 60/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 340 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 392
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 393 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 451
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 452 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 511
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 512 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 571
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 572 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 630
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + ++ + +Q + +
Sbjct: 631 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQF 690
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 691 ERDLQARDEQNEEKRRQLQRQLHE 714
Score = 56.8 bits (131), Expect = 2e-07
Identities = 85/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 651 LETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 710
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED E A KKK + + D + Q D K + A K+ K QA++
Sbjct: 711 QLHEYETELEDERNE-RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 769
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 770 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 829
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 830 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 886
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 887 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 927
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 928 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 985
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 986 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1042
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 847 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 906
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 907 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 966
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 967 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1020
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 30 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 89
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 90 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 149
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 150 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 181
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 928 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 987
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 988 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1021
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 950 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1009
Query: 85 QFEINRKRDTEL 96
RK EL
Sbjct: 1010 INANRRKLQREL 1021
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1229
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1469 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1036
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 1037 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1215
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1216 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1275
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1276 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1428
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1454
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1573
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1692
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1752
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1753 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1813 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1851
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1143
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1203 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1262 QELQSKCSDGERARAEL 1278
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1279 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1516
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1597 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1715
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1773 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1813
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1814 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1871
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1872 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 975
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 976 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1035
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 85 QFEINRKRDTEL 96
RK EL
Sbjct: 1896 INANRRKLQREL 1907
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1169
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1170 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1229
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1230 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1289
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1290 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1349
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1408
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1409 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1468
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1469 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1515
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 977 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1036
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 1037 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1156 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1215
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1216 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1275
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1276 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1391
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1392 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1428
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1454
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1573
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1574 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1633
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1634 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1692
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1693 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1752
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1753 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1812
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1813 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1851
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 844 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 903
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1083
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 1084 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1143
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1144 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1202
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1203 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1262 QELQSKCSDGERARAEL 1278
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1226 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1279 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1397
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1398 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1516
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHE 1600
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1537 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1596
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1597 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1655
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1656 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1715
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1773 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1813
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1814 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1871
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1872 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1853 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1906
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 916 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 975
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 976 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1035
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1873
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1874 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1907
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1836 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1895
Query: 85 QFEINRKRDTEL 96
RK EL
Sbjct: 1896 INANRRKLQREL 1907
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1236
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1476 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 1044 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1223 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1283 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1435
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1461
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1580
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1699
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1759
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1760 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1820 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1858
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1150
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1210 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1269 QELQSKCSDGERARAEL 1285
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1286 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1523
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1604 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1722
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1780 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1820
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1821 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1878
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1879 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1860 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 982
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 983 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 85 QFEINRKRDTEL 96
RK EL
Sbjct: 1903 INANRRKLQREL 1914
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1176
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1177 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1236
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1237 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1296
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1297 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1356
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1415
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1416 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1475
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1476 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1522
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 984 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1043
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 1044 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1163 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1222
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1223 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1282
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1283 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1398
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1399 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1435
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1461
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1580
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1581 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1640
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1641 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1699
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1700 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1759
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1760 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1819
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1820 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1858
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 851 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 910
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1090
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 1091 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1150
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1151 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1209
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1210 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1269 QELQSKCSDGERARAEL 1285
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1233 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1286 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1404
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1405 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1523
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1524 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1583
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1584 ERDLQARDEQNEEKRRQLQRQLHE 1607
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1544 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1603
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1604 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1662
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1663 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1722
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1780 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1820
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1821 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1878
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1879 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1860 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1913
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 923 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 982
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 983 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1843 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1902
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 1903 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1880
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1881 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1914
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 995 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1054
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1055 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1114
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1115 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1174
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1175 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1234
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1235 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1293
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1294 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1353
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1354 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1400
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 862 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 921
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 922 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 980
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 981 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1040
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1041 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1100
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1101 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1160
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1161 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1216
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1217 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1276
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1277 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1313
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1281 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1339
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1340 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1399
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1400 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1458
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1459 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1518
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1519 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1577
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1578 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1637
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1638 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1697
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1698 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1736
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 729 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 788
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 789 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 848
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 849 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 908
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 909 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 968
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 969 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1028
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1029 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1087
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1088 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1146
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1147 QELQSKCSDGERARAEL 1163
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1111 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1163
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1164 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1222
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1223 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1282
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1283 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1342
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1343 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1401
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1402 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1461
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1462 ERDLQARDEQNEEKRRQLQRQLHE 1485
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1422 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1481
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1482 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1540
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1541 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1600
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1601 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1657
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1658 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1698
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1699 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1756
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1757 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1813
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1618 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1677
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1678 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1737
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1738 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1791
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 801 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 860
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 861 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 920
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 921 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 952
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1721 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1780
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 1781 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1818
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1699 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1758
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1759 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1792
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 141 bits (341), Expect = 6e-33
Identities = 90/407 (22%), Positives = 182/407 (44%), Gaps = 1/407 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE I +Q+DL+SER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1122 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELR 1181
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K L++ E +++K+ + V + EQ++Q + KA +K K
Sbjct: 1182 AKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTL 1241
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +L ++ + + K + ++LE + EL K + R ++ +L E
Sbjct: 1242 EKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEV 1301
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + + ++SQ L Q+E + S++
Sbjct: 1302 ESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ 1361
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QL+EE EA+ +LER + N ++ + K ++
Sbjct: 1362 DQLDEEMEAKQNLERHISTLNIQLSDSKKKL-QDFASTVEALEEGKKRFQKEIENLTQQY 1420
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 1421 EEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA 1480
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 1481 DERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 1527
Score = 71.7 bits (168), Expect = 6e-12
Identities = 90/457 (19%), Positives = 171/457 (37%), Gaps = 9/457 (1%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E KI+ ++D++ + ++ +E+ L ++ L+ L E E A++ ++ K ++ +
Sbjct: 989 EAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMI 1048
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+L L+ +S + LK+K + DF EQI L A + + +K + E+
Sbjct: 1049 SELEVRLKKEE-KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1107
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
LA++++ +K K LE IS+L ++ K+ L +E L E+
Sbjct: 1108 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTEL 1167
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID-LESVRVQLEE- 274
+D + L+++ + + Q +E + QLE+
Sbjct: 1168 EDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQF 1227
Query: 275 -ESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
++A LD +Q L K N ++ +
Sbjct: 1228 KRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR 1287
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
A++N+ + +LQ+EVE + L +A G A +L K L + + L+E +
Sbjct: 1288 -AELND---KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1343
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
LR + E + +LD+ E K L R + L D++ +
Sbjct: 1344 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALE 1403
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
T Y+E A E+ RL E
Sbjct: 1404 EGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQE 1440
Score = 67.7 bits (158), Expect = 9e-11
Identities = 78/461 (16%), Positives = 172/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 1408 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 1466
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 1467 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1526
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 1527 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 1585
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 1586 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 1645
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + +QL K ++ ++ + L
Sbjct: 1646 DSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 1704
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 1705 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 1764
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 1765 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 1824
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 1825 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 1863
Score = 64.9 bits (151), Expect = 6e-10
Identities = 84/437 (19%), Positives = 178/437 (40%), Gaps = 27/437 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL----EEAEGGAESQ 85
L ++R E++++ +D+L+ +E +Q+ E E +L + QL+E E+ + E
Sbjct: 856 LLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELY 915
Query: 86 FEINRKRDTELLKLRKLLEDVH-----LESEETA----HLLKKKNQEIVIDFQEQIDQLT 136
E R K ++L E +H LE EE +KK + ++D +EQ+++
Sbjct: 916 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 975
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ + + EK +A++ +L ++ + + +SK + LE IS+L + E
Sbjct: 976 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1035
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++T K + EL ++ + + + + LK ++
Sbjct: 1036 NLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKM 1095
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L + E +L++ +L++E + + +++ + G I +
Sbjct: 1096 QLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRD 1155
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT------------A 364
TL + E + R + EV VL L++ + A
Sbjct: 1156 LGEELEALKTELEDTLDSTATQQELRAKR-EQEVTVLKKALDEETRSHEAQVQEMRQKHA 1214
Query: 365 RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA 424
+ +++ TEQLE+ K+ L++ Q E+ DL + L + E++ +++ +A
Sbjct: 1215 QAVEELTEQLEQFK-RAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1273
Query: 425 RENKKMGDDLHDARANI 441
+E + D ARA +
Sbjct: 1274 QELQSKCSDGERARAEL 1290
Score = 59.7 bits (138), Expect = 2e-08
Identities = 61/384 (15%), Positives = 153/384 (39%), Gaps = 10/384 (2%)
Query: 54 RQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
+Q +E+E ADL+ ++ L + +E E +K + ++ +L+ D E
Sbjct: 1238 KQTLEKENADLAGELRVLGQAKQEVE-------HKKKKLEAQVQELQSKCSDGERARAEL 1290
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKT 173
+ K E+ +++ + K+ + +++ + ++ T++K+ +S
Sbjct: 1291 NDKVHKLQNEVE-SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1349
Query: 174 CERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+LE + L +++E ++ H L+ + + K++QD +E + K +
Sbjct: 1350 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRF 1409
Query: 234 ASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ + ++++ +L+ + V L+ + + +LE++ K + +
Sbjct: 1410 QKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLL 1469
Query: 294 GHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL 353
++ K + L AK +E+ L++E+E L
Sbjct: 1470 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDL 1528
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
+ + EL+K LE E+K++LEE + T+ + +Q + +
Sbjct: 1529 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1588
Query: 414 DKTREQKDALARENKK-MGDDLHD 436
++ + +D E ++ + LH+
Sbjct: 1589 ERDLQARDEQNEEKRRQLQRQLHE 1612
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 1549 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 1608
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 1609 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 1667
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 1668 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 1727
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 1728 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1784
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 1785 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 1825
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 1826 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 1883
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 1884 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1940
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 1745 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1804
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 1805 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1864
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 1865 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 1918
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/152 (15%), Positives = 63/152 (41%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K L+ + + LE+ ++LQ +++ + ++++ +LEE ++ Q +
Sbjct: 928 KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVT 987
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXX 461
+ +++++ E+ +Q + L++E K + + + D N+
Sbjct: 988 AEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESM 1047
Query: 462 XXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQF 493
K+ E R+ E+ ++L + F
Sbjct: 1048 ISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1079
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 1848 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 1907
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 1908 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 1945
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 1826 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 1885
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 1886 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 1919
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 121 bits (291), Expect = 7e-27
Identities = 84/405 (20%), Positives = 178/405 (43%), Gaps = 1/405 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L +L + + Q+DLESER R + E+++ DL ++ L LE+ +Q E+
Sbjct: 1127 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ +L+K LE+ E L++++ + + + EQ++Q + K EK +
Sbjct: 1187 SKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL 1246
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+AEV EL A++ ++ + + RLE+ + E+ + + R + QR E
Sbjct: 1247 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 1306
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + S +Q + + +E + +R
Sbjct: 1307 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 1366
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QLEEE+ AR R+L A ++ WR + + +
Sbjct: 1367 EQLEEEAAARERAGRELQTAQAQLSEWRRR-QEEEAGALEAGEEARRRAAREAEALTQRL 1425
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ +E+ + RLQ E++ +DLE+ L+K+ + +++ E K+ + V
Sbjct: 1426 AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAV 1485
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + R ++ ++ L++ +E ++ L R+N+ + +L
Sbjct: 1486 EERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1530
Score = 57.6 bits (133), Expect = 1e-07
Identities = 88/477 (18%), Positives = 174/477 (36%), Gaps = 24/477 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S + +E + +++ LE E R+R RE Q+ + R EE G E+ E R
Sbjct: 1353 SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARR 1412
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ E L + L + E+ + +++ Q+ + D ++Q + + EK++ KF
Sbjct: 1413 RAAREAEALTQRLAE-KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFD 1471
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ E A V +E+ ER E E + L R + + ++ L ++N
Sbjct: 1472 QLLAEEKAAVLRAVEER-------ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1524
Query: 211 ELVKEVQDLKVNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH-QVEI 263
L E++ L + ++V + ++A Q ++E+
Sbjct: 1525 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1584
Query: 264 DLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+++++ Q E + E R L +QL A E R K
Sbjct: 1585 TVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER-KQRTLAVAARKKLEGEL 1643
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
+ + ++ ++ Q L EVE E+ RE +KR + LE
Sbjct: 1644 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1703
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
+ ++ L + + Q Q+D E+ + E+K L ++ ++L
Sbjct: 1704 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1763
Query: 436 DARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
+ ++N + +AE+GR+ E++ Q L G+
Sbjct: 1764 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 1820
Score = 55.2 bits (127), Expect = 5e-07
Identities = 86/470 (18%), Positives = 174/470 (37%), Gaps = 13/470 (2%)
Query: 33 LSRLEDKIRLIQDDLES----ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
L+ + ++ L+ +LE+ E E ++++ EK L + +L LE AE GA + ++
Sbjct: 930 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE-AEEGARQKLQL 988
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAE-KEK 146
K TE K++K ED+ L ++ + L K + ++ QL + + +RA
Sbjct: 989 E-KVTTEA-KMKKFEEDLLLLEDQNSKLSKSGSCWKIVWPSSHPRQLRRRRRSRASISYG 1046
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
S + + ++ K + + K RL+ SEL ++ E + ++ + R
Sbjct: 1047 SNMRPQSQTWRDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKE 1106
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI--D 264
+E + +D LKS +Q A + ++ +
Sbjct: 1107 EELQAALARAED--EGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 1164
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE++R +LE+ ++ + K E+ + ++
Sbjct: 1165 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1224
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
EK + L++EV L +L +E ++R +LE E++ R
Sbjct: 1225 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 1284
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXX 444
+ + + L+ Q EL+ VS L++ + L++E LHDA+ +
Sbjct: 1285 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 1344
Query: 445 XXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+E A R+ + Q A+ ++R
Sbjct: 1345 TRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394
Score = 51.2 bits (117), Expect = 8e-06
Identities = 72/386 (18%), Positives = 145/386 (37%), Gaps = 22/386 (5%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E EL E K L V V L + E G + E R++ + L+ ++ D
Sbjct: 1567 ELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 1625
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ A +KK + + + + Q+ + K A K+ K QA++ EL +VE +
Sbjct: 1626 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 1685
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I E + L ++ L + +++ Q+ E+ EV + ++ ++
Sbjct: 1686 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 1745
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-------SEARL 280
K Q+ + ++ + +ES+ +L E R
Sbjct: 1746 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1805
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
LERQ+ + G +G + K + I V
Sbjct: 1806 QLERQIQELRGRLG---EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1862
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + RL+ +++ +E+ A +L+ +QLE+ N+ +K + + E+ + +
Sbjct: 1863 RAEKRLKE----VVLQVEEERRVADQLR---DQLEKGNLRVK----QLKRQLEEAEEEAS 1911
Query: 401 NKQTELQRVSHELDKTREQKDALARE 426
Q +R+ EL+ E +++ RE
Sbjct: 1912 RAQAGRRRLQRELEDVTESAESMNRE 1937
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELL 97
++ + +L +ER + E + L Q+ +L RL E + GA ++ ++ +++L
Sbjct: 1782 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1841
Query: 98 KLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + LE E + L++ K+ +E+V+ +E+ + + R + EK + V
Sbjct: 1842 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE--RRVADQLRDQLEKGNLR--VK 1897
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
+L Q+E +E RL+ + ++ E +NR + + + +R
Sbjct: 1898 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1947
Score = 38.3 bits (85), Expect = 0.064
Identities = 46/264 (17%), Positives = 107/264 (40%), Gaps = 6/264 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
++A +LE ++ ++ + S + ++ ++ + Q+ +L +EE E F N
Sbjct: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1692
Query: 90 RKRDTELLKLRKLLEDVHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ + L L E + L+ E A +++ Q+ + +++ +KA +EK +
Sbjct: 1693 RESEKRLKGLE--AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQ 1750
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + +L ++E ++ +L + + L ++ S +Q+L ++
Sbjct: 1751 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1810
Query: 209 NIELVKEV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
EL + +D + + + + + S+ + + E L+
Sbjct: 1811 IQELRGRLGEEDAGARARHKMTI-AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 1869
Query: 267 SVRVQLEEESEARLDLERQLVKAN 290
V +Q+EEE L QL K N
Sbjct: 1870 EVVLQVEEERRVADQLRDQLEKGN 1893
Score = 33.5 bits (73), Expect = 1.8
Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 6/97 (6%)
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY---ELLAQVENVTKEKITISKTCE 175
+K QE+ ++ +L A+ E+E+++ ++ EL A+ E T+ ++ K +
Sbjct: 879 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE-TRGRLAARK--Q 935
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
LE+ +SEL ++ E + + K+RL Q EL
Sbjct: 936 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQEL 972
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 121 bits (291), Expect = 7e-27
Identities = 84/405 (20%), Positives = 178/405 (43%), Gaps = 1/405 (0%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L +L + + Q+DLESER R + E+++ DL ++ L LE+ +Q E+
Sbjct: 703 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 762
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ +L+K LE+ E L++++ + + + EQ++Q + K EK +
Sbjct: 763 SKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL 822
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+AEV EL A++ ++ + + RLE+ + E+ + + R + QR E
Sbjct: 823 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 882
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + + + S +Q + + +E + +R
Sbjct: 883 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 942
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
QLEEE+ AR R+L A ++ WR + + +
Sbjct: 943 EQLEEEAAARERAGRELQTAQAQLSEWRRR-QEEEAGALEAGEEARRRAAREAEALTQRL 1001
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
++ +E+ + RLQ E++ +DLE+ L+K+ + +++ E K+ + V
Sbjct: 1002 AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAV 1061
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + R ++ ++ L++ +E ++ L R+N+ + +L
Sbjct: 1062 EERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1106
Score = 69.3 bits (162), Expect = 3e-11
Identities = 86/470 (18%), Positives = 180/470 (38%), Gaps = 13/470 (2%)
Query: 33 LSRLEDKIRLIQDDLES----ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
L+ + ++ L+ +LE+ E E ++++ EK L + +L LE AE GA + ++
Sbjct: 506 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE-AEEGARQKLQL 564
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEK 146
K TE K++K ED+ L ++ + L K++ ++ + +F Q + + K +
Sbjct: 565 E-KVTTEA-KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLR 622
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
K++A + ++ ++ K + + K RL+ SEL ++ E + ++ + R
Sbjct: 623 LKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKE 682
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI--D 264
+E + +D LKS +Q A + ++ +
Sbjct: 683 EELQAALARAED--EGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEE 740
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE++R +LE+ ++ + K E+ + ++
Sbjct: 741 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 800
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
EK + L++EV L +L +E ++R +LE E++ R
Sbjct: 801 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGR 860
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXX 444
+ + + L+ Q EL+ VS L++ + L++E LHDA+ +
Sbjct: 861 AGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEE 920
Query: 445 XXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+E A R+ + Q A+ ++R
Sbjct: 921 TRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 970
Score = 64.9 bits (151), Expect = 6e-10
Identities = 80/413 (19%), Positives = 170/413 (41%), Gaps = 24/413 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+++LE++ + + L +E EL E + L+ + +L + E E + E +R+
Sbjct: 475 VAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQM 534
Query: 93 DTELLKLRKLLEDV--HLESEETAHL---LKKKNQEIVID-FQEQIDQLTKTKARAEKEK 146
TE +L++ ++++ HLE+EE A L+K E + F+E + L ++ KE+
Sbjct: 535 QTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKER 594
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + E +Q ++ +++K + E TI+++ ++ + + ++ K+RL
Sbjct: 595 KLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLD 654
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E+ EL +++ + + E + + + SL + + L
Sbjct: 655 GESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA 714
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
+ LE E AR E+Q E+ R + +
Sbjct: 715 EAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE------ 768
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+ ++ ++++R+ E + +L + +G A L + EQLE+ K E
Sbjct: 769 ------VTELKKTLEEETRIH---EAAVQELRQRHGQA--LGELAEQLEQAR-RGKGAWE 816
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+T E +LR + + LQ E ++ R + + +E + D ARA
Sbjct: 817 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 869
Score = 57.6 bits (133), Expect = 1e-07
Identities = 88/477 (18%), Positives = 174/477 (36%), Gaps = 24/477 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S + +E + +++ LE E R+R RE Q+ + R EE G E+ E R
Sbjct: 929 SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARR 988
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ E L + L + E+ + +++ Q+ + D ++Q + + EK++ KF
Sbjct: 989 RAAREAEALTQRLAE-KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFD 1047
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ E A V +E+ ER E E + L R + + ++ L ++N
Sbjct: 1048 QLLAEEKAAVLRAVEER-------ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1100
Query: 211 ELVKEVQDLKVNIENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH-QVEI 263
L E++ L + ++V + ++A Q ++E+
Sbjct: 1101 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1160
Query: 264 DLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
+++++ Q E + E R L +QL A E R K
Sbjct: 1161 TVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER-KQRTLAVAARKKLEGEL 1219
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLE 375
+ + ++ ++ Q L EVE E+ RE +KR + LE
Sbjct: 1220 EELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1279
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
+ ++ L + + Q Q+D E+ + E+K L ++ ++L
Sbjct: 1280 AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1339
Query: 436 DARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
+ ++N + +AE+GR+ E++ Q L G+
Sbjct: 1340 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 1396
Score = 51.2 bits (117), Expect = 8e-06
Identities = 72/386 (18%), Positives = 145/386 (37%), Gaps = 22/386 (5%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E EL E K L V V L + E G + E R++ + L+ ++ D
Sbjct: 1143 ELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 1201
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ A +KK + + + + Q+ + K A K+ K QA++ EL +VE +
Sbjct: 1202 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 1261
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I E + L ++ L + +++ Q+ E+ EV + ++ ++
Sbjct: 1262 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 1321
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-------SEARL 280
K Q+ + ++ + +ES+ +L E R
Sbjct: 1322 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1381
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
LERQ+ + G +G + K + I V
Sbjct: 1382 QLERQIQELRGRLG---EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 1438
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + RL+ +++ +E+ A +L+ +QLE+ N+ +K + + E+ + +
Sbjct: 1439 RAEKRLKE----VVLQVEEERRVADQLR---DQLEKGNLRVK----QLKRQLEEAEEEAS 1487
Query: 401 NKQTELQRVSHELDKTREQKDALARE 426
Q +R+ EL+ E +++ RE
Sbjct: 1488 RAQAGRRRLQRELEDVTESAESMNRE 1513
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELL 97
++ + +L +ER + E + L Q+ +L RL E + GA ++ ++ +++L
Sbjct: 1358 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1417
Query: 98 KLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + LE E + L++ K+ +E+V+ +E+ + + R + EK + V
Sbjct: 1418 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE--RRVADQLRDQLEKGNLR--VK 1473
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
+L Q+E +E RL+ + ++ E +NR + + + +R
Sbjct: 1474 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 1523
Score = 38.3 bits (85), Expect = 0.064
Identities = 46/264 (17%), Positives = 107/264 (40%), Gaps = 6/264 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
++A +LE ++ ++ + S + ++ ++ + Q+ +L +EE E F N
Sbjct: 1209 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1268
Query: 90 RKRDTELLKLRKLLEDVHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ + L L E + L+ E A +++ Q+ + +++ +KA +EK +
Sbjct: 1269 RESEKRLKGLE--AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQ 1326
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + +L ++E ++ +L + + L ++ S +Q+L ++
Sbjct: 1327 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1386
Query: 209 NIELVKEV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
EL + +D + + + + + S+ + + E L+
Sbjct: 1387 IQELRGRLGEEDAGARARHKMTI-AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 1445
Query: 267 SVRVQLEEESEARLDLERQLVKAN 290
V +Q+EEE L QL K N
Sbjct: 1446 EVVLQVEEERRVADQLRDQLEKGN 1469
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 117 bits (282), Expect = 9e-26
Identities = 64/238 (26%), Positives = 113/238 (47%)
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+L D + +R Q EEE+EA+ +L+R L KAN E+ WR+K+
Sbjct: 8 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 67
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
K + + AK +++EK K RLQ+E+E L++D+E++N A L K+ ++
Sbjct: 68 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 127
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E K + EE+ E +Q++ R+ TEL ++ + +++ E + RENK + +++ D
Sbjct: 128 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 187
Query: 437 ARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +A +EAEA + EE + R EF Q +
Sbjct: 188 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 245
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/421 (20%), Positives = 172/421 (40%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + S+ RL+++I + D+E +++++ + + + ++ EE++
Sbjct: 83 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 142
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
ES + R TEL KL+ E+ LE ET K QE + D EQ+ KT
Sbjct: 143 LESSQKEARSLSTELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 201
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + +AE EL + +E R ++ +++ +IE R + +
Sbjct: 202 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---RKLAEKDEE 258
Query: 202 KQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++ + ++ +V +Q D + N + +K ++
Sbjct: 259 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 318
Query: 258 LHQVEIDLESVRVQLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXX 310
+ ++ L+ ++QL++ A DL ER+ E+ R+
Sbjct: 319 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKL 377
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ S +LI + ++ S+LQ+EVE + + EKA +
Sbjct: 378 ADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD 437
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 438 AAMMAEELKKEQ-DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 496
Query: 426 E 426
E
Sbjct: 497 E 497
Score = 67.3 bits (157), Expect = 1e-10
Identities = 70/416 (16%), Positives = 164/416 (39%), Gaps = 21/416 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + + L S + +E+ + L + ++L LEEAE E + + E
Sbjct: 181 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLE 240
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ +E E +E K+ + +V Q +D T+++ A + K K + ++ E
Sbjct: 241 FNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 300
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ Q+ + + K + L+ + + I++++ R D+ + + + N L E
Sbjct: 301 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 360
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + +++ DL ++ ++EE
Sbjct: 361 LEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 420
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ + E + KA + +
Sbjct: 421 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 480
Query: 336 INNVEKQKSRLQSEVEVLIIDLE---KANGTA----RELQKRTEQL------ERVNI--- 379
+ +KQ +L++ V L +LE K N + R+ ++R ++L +R N+
Sbjct: 481 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 540
Query: 380 -EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + ++ ++V HELD+ E+ D + K+
Sbjct: 541 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 596
Score = 63.7 bits (148), Expect = 1e-09
Identities = 74/415 (17%), Positives = 154/415 (37%), Gaps = 10/415 (2%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINR 90
AL L+++ E E E + ++R + + +V Q + E +A E E +
Sbjct: 8 ALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKK 67
Query: 91 KRDTELLKLRKLLEDVHLES---EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
K L + + +E V+ + E+T H L+ + +++++D +++ A +K++
Sbjct: 68 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQR 123
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
F + E + E E + K L + +L EE + + L +
Sbjct: 124 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 183
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +L +++ I + ++ Q+ ++ + + +++
Sbjct: 184 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQ 243
Query: 268 VRVQLEEESEARLDLERQLVKANG-EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ ++E + A D E + K N + K
Sbjct: 244 IKAEIERKL-AEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEME 302
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KQ LQS ++ I L+ A +L++ +ER N +++ LE
Sbjct: 303 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 362
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + EQT+R + EL S + Q +L + KKM DL + +
Sbjct: 363 ELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 417
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 113 bits (273), Expect = 1e-24
Identities = 63/238 (26%), Positives = 111/238 (46%)
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+L D + +R Q EEE+EA+ L+ L KAN E+ WR+K+
Sbjct: 32 ALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQWRTKYETDAIQRTEELEEAKK 91
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
K + + AK +++EK K RLQ+E+E L++D+E++N A L K+ ++
Sbjct: 92 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDK 151
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ E K + EE+ E +Q++ R+ TEL ++ + +++ E + RENK + +++ D
Sbjct: 152 ILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISD 211
Query: 437 ARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+ +A +EAEA + EE + R EF Q +
Sbjct: 212 LTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 269
Score = 68.9 bits (161), Expect = 4e-11
Identities = 70/416 (16%), Positives = 164/416 (39%), Gaps = 21/416 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + + L S + +E+ + L + ++L LEEAE E + + E
Sbjct: 205 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLE 264
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ +E E +E K+ + +V Q +D T+++ A + K K + ++ E
Sbjct: 265 FNQIKAEIERKRQEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 324
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ Q+ + + K + L+ + + I++++ R D+ + + + N L E
Sbjct: 325 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 384
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + +++ DL ++ ++EE
Sbjct: 385 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 444
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ + E + KA + +
Sbjct: 445 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 504
Query: 336 INNVEKQKSRLQSEVEVLIIDLE---KANGTA----RELQKRTEQL------ERVNI--- 379
+ +KQ +L++ V L +LE K N + R+ ++R ++L +R N+
Sbjct: 505 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 564
Query: 380 -EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + ++ ++V HELD+ E+ D + K+
Sbjct: 565 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 620
Score = 67.7 bits (158), Expect = 9e-11
Identities = 83/418 (19%), Positives = 168/418 (40%), Gaps = 16/418 (3%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + S+ RL+++I + D+E +++++ + + + ++ EE++
Sbjct: 107 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 166
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
ES + R TEL KL+ E+ LE ET K QE + D EQ+ KT
Sbjct: 167 LESSQKEARSLSTELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 225
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + +AE EL + +E R ++ +++ +IE + +
Sbjct: 226 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQ 285
Query: 202 KQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+R ++ ++ D + N + +K ++ +
Sbjct: 286 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 345
Query: 261 VEIDLESVRVQLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++ L+ ++QL++ A DL ER+ E+ R+
Sbjct: 346 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQ 404
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQK 369
+ S +LI + ++ S+LQ+EVE + + EKA +
Sbjct: 405 ELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAM 464
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALARE 426
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A RE
Sbjct: 465 MAEELKKEQ-DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 521
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/415 (17%), Positives = 157/415 (37%), Gaps = 10/415 (2%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINR 90
AL L+++ E E E + R++ + + + +V Q + E +A E E +
Sbjct: 32 ALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQWRTKYETDAIQRTEELEEAKK 91
Query: 91 KRDTELLKLRKLLEDVHLES---EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
K L + + +E V+ + E+T H L+ + +++++D +++ A +K++
Sbjct: 92 KLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQR 147
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
F + E + E E + K L + +L EE + + L +
Sbjct: 148 NFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE 207
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +L +++ I + ++ Q+ ++ + + +++
Sbjct: 208 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQ 267
Query: 268 VRVQLEEESEARLDLERQLVKANG-EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ ++E + + + D E + K N + K
Sbjct: 268 IKAEIERKRQEK-DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEME 326
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KQ LQS ++ I L+ A +L++ +ER N +++ LE
Sbjct: 327 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 386
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + EQT+R + + EL S + Q +L + KKM DL + +
Sbjct: 387 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEV 441
Score = 58.0 bits (134), Expect = 7e-08
Identities = 48/276 (17%), Positives = 101/276 (36%), Gaps = 2/276 (0%)
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL-V 213
+L Q+E K K ++ + L + EE + + + E +
Sbjct: 14 DLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKARLQGDLSKANSEVAQWRT 73
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
K D E + K ++A + + H+++ ++E + V +E
Sbjct: 74 KYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 133
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
+ A L+++ + + W+ K+ S +
Sbjct: 134 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-LSTELFKLKNAYEESL 192
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ +++ LQ E+ L L + T EL+K +QLE +E++S LEE E
Sbjct: 193 EHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLE 252
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ + Q E ++ E+++ R++KD + K+
Sbjct: 253 HEEGKILRAQLEFNQIKAEIERKRQEKDEEMEQAKR 288
Score = 39.9 bits (89), Expect = 0.021
Identities = 33/130 (25%), Positives = 61/130 (46%), Gaps = 7/130 (5%)
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L L++ LE+ AH L+ + + +EQ ++ T+ KAR + + SK +EV
Sbjct: 11 QLGDLKRQLEEEVKAKNALAHALQSARHDCDL-LREQYEEETEAKARLQGDLSKANSEV- 68
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
AQ TK + + E LE +L +++E + + + L + L
Sbjct: 69 ---AQWR--TKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 123
Query: 215 EVQDLKVNIE 224
E++DL V++E
Sbjct: 124 EIEDLMVDVE 133
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 109 bits (262), Expect = 2e-23
Identities = 72/270 (26%), Positives = 123/270 (45%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E EL +V+ + + K +++E + EL +K E R ++ +L E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ + + S + SQ L QVE + S R
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSK 299
QLEEE EA+ +LE+Q+ + ++ + K
Sbjct: 1343 EQLEEEEEAKHNLEKQIATLHAQVADMKKK 1372
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/417 (17%), Positives = 166/417 (39%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 961 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ + + + +++E E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 944 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 1063 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 1118
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 990
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 991 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 1050
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 1111 SQISELQEDL 1120
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE + + LQ +++++ E++ +LEE
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Score = 31.9 bits (69), Expect = 5.5
Identities = 16/85 (18%), Positives = 41/85 (48%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + + Q + +
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE 965
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 88.2 bits (209), Expect = 6e-17
Identities = 52/179 (29%), Positives = 90/179 (50%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L + LE +I +Q+DLESER R + E++K DL ++ L LE+ +Q E+
Sbjct: 1103 LKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
KR+ E+ L+K LE+ E +++K+ + V + EQ++Q + KA EK K
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E EL +V+ + + K +++E + EL +K E R ++ +L E
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVE 1281
Score = 69.7 bits (163), Expect = 2e-11
Identities = 73/417 (17%), Positives = 166/417 (39%), Gaps = 6/417 (1%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E +
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQ 960
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKAR 141
++ ++ T KL+KL E+ + ++ L K+K ++ + +F + + +
Sbjct: 961 ---KLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS 1017
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
K K+K +A + +L ++ K++ + KT +LE ++L +I EL I ++
Sbjct: 1018 LAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ 1077
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ +E + V++ + ++ SQ +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDL 1137
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+LE+++ +LE+ ++ + K E+ + K+S
Sbjct: 1138 GEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
N+EK K L++E L +++ + + + +++E E+
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL 1257
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ + E ++ + + Q EL V+ L ++ + L ++ + L D +
Sbjct: 1258 QVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314
Score = 57.2 bits (132), Expect = 1e-07
Identities = 69/404 (17%), Positives = 157/404 (38%), Gaps = 9/404 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 884 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 943
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +L + LE+ + + L K + + +E+ L + KEK + +
Sbjct: 944 NIQELEEQLEEEE-SARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIA 1002
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
E + ++ +++K + E I++L ++ + ++ +++L ++ +L
Sbjct: 1003 EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSD 1062
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
++ +L+ I LK Q+A + +L ++ +LES +L+E
Sbjct: 1063 QIAELQAQIAE---LKMQLAKKEEELQAALARVEEEAAQKNMALKKIR-ELESQISELQE 1118
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL-- 332
+ E+ + K ++G S TL
Sbjct: 1119 DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
Query: 333 IAKINNVEKQKSRLQ--SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
AK + + Q+ R + VE L LE+ L+K + LE E+ + ++ +Q
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQ 1238
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ + + +LQ + + ++ + LA + K+ +L
Sbjct: 1239 GKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 36.7 bits (81), Expect = 0.19
Identities = 33/190 (17%), Positives = 78/190 (41%), Gaps = 9/190 (4%)
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
A +++ +++ + QLEEE AR L+ + V ++ K
Sbjct: 936 AEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKL-----KKLEEEQIILEDQNCKL 990
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRT 371
K T + + K ++L+++ E +I DLE + +EL+K
Sbjct: 991 AKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTR 1050
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+LE + ++ ++ E + + L K+ ELQ +++ QK+ ++ +++
Sbjct: 1051 RKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELE 1110
Query: 432 DDLHDARANI 441
+ + + ++
Sbjct: 1111 SQISELQEDL 1120
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/115 (20%), Positives = 55/115 (47%), Gaps = 4/115 (3%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEE 387
L A+ + + + + E+E + DLE + + LQ +++++ E++ +LEE
Sbjct: 895 LCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
++ Q + + +L+++ E +Q LA+E K + D + + N+T
Sbjct: 955 EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLT 1009
Score = 31.9 bits (69), Expect = 5.5
Identities = 16/85 (18%), Positives = 41/85 (48%)
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
+K +LQ +++ +A L + ++LE + ++++R+EE + + Q + +
Sbjct: 881 EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKK 940
Query: 402 KQTELQRVSHELDKTREQKDALARE 426
Q +Q + +L++ + L E
Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLE 965
>BC022376-1|AAH22376.1| 627|Homo sapiens Unknown (protein for
IMAGE:4338358) protein.
Length = 627
Score = 87.8 bits (208), Expect = 8e-17
Identities = 46/160 (28%), Positives = 79/160 (49%)
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
L+ + KAN E+ WR+K+ K + + AK ++EK
Sbjct: 450 LDTKQPKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEK 509
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
K RLQ+EVE L+ID+E+ N L K+ +++ E K + EET E +Q++ R+
Sbjct: 510 TKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRS 569
Query: 402 KQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
TEL ++ + +++ +Q + L RENK + ++ D I
Sbjct: 570 LSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 609
Score = 41.1 bits (92), Expect = 0.009
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 1/127 (0%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + ++ RL++++ + D+E +++++ + + + ++ EE
Sbjct: 500 VNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE 559
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
E+ + +R TEL K++ E+ L+ ET K Q+ + D EQI + K +
Sbjct: 560 LEASQKESRSLSTELFKIKNAYEE-SLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHK 618
Query: 142 AEKEKSK 148
+K+K K
Sbjct: 619 KKKKKKK 625
>X06976-1|CAA30039.1| 543|Homo sapiens beta myosin heavy chain (
544 AA) protein.
Length = 543
Score = 83.8 bits (198), Expect = 1e-15
Identities = 44/161 (27%), Positives = 81/161 (50%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+ E
Sbjct: 17 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 76
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXX 453
+Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 77 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 136
Query: 454 XXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 137 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 177
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/421 (20%), Positives = 172/421 (40%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + S+ RL+++I + D+E +++++ + + + ++ EE++
Sbjct: 15 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 74
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
ES + R TEL KL+ E+ LE ET K QE + D EQ+ KT
Sbjct: 75 LESSQKEARSLSTELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 133
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + +AE EL + +E R ++ +++ +IE R + +
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---RKLAEKDEE 190
Query: 202 KQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++ + ++ +V +Q D + N + +K ++
Sbjct: 191 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 250
Query: 258 LHQVEIDLESVRVQLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXX 310
+ ++ L+ ++QL++ A DL ER+ E+ R+
Sbjct: 251 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKL 309
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ S +LI + ++ S+LQ+EVE + + EKA +
Sbjct: 310 ADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD 369
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 370 AAMMAEELKKEQ-DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 428
Query: 426 E 426
E
Sbjct: 429 E 429
Score = 67.3 bits (157), Expect = 1e-10
Identities = 70/416 (16%), Positives = 164/416 (39%), Gaps = 21/416 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + + L S + +E+ + L + ++L LEEAE E + + E
Sbjct: 113 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLE 172
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ +E E +E K+ + +V Q +D T+++ A + K K + ++ E
Sbjct: 173 FNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 232
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ Q+ + + K + L+ + + I++++ R D+ + + + N L E
Sbjct: 233 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 292
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + +++ DL ++ ++EE
Sbjct: 293 LEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 352
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ + E + KA + +
Sbjct: 353 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 412
Query: 336 INNVEKQKSRLQSEVEVLIIDLE---KANGTA----RELQKRTEQL------ERVNI--- 379
+ +KQ +L++ V L +LE K N + R+ ++R ++L +R N+
Sbjct: 413 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 472
Query: 380 -EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + ++ ++V HELD+ E+ D + K+
Sbjct: 473 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 528
Score = 53.6 bits (123), Expect = 2e-06
Identities = 33/171 (19%), Positives = 70/171 (40%), Gaps = 1/171 (0%)
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 27 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 85
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 86 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 145
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 146 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 196
Score = 52.8 bits (121), Expect = 3e-06
Identities = 57/332 (17%), Positives = 120/332 (36%), Gaps = 6/332 (1%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
E+T H L+ + +++++D +++ A +K++ F + E + E E +
Sbjct: 23 EKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 78
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLK 230
K L + +L EE + + L +E +L +++ I + ++
Sbjct: 79 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVR 138
Query: 231 SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
Q+ ++ + + +++ ++ ++E + A D E + K N
Sbjct: 139 KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRN 197
Query: 291 G-EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE 349
+ K +KQ LQS
Sbjct: 198 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 257
Query: 350 VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
++ I L+ A +L++ +ER N +++ LEE + EQT+R + EL
Sbjct: 258 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIET 317
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARANI 441
S + Q +L + KKM DL + +
Sbjct: 318 SERVQLLHSQNTSLINQKKKMDADLSQLQTEV 349
>M17712-1|AAA36343.1| 543|Homo sapiens protein ( Human cardiac
myosin heavy chain mRNA, 3' end. ).
Length = 543
Score = 83.8 bits (198), Expect = 1e-15
Identities = 44/161 (27%), Positives = 81/161 (50%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+ E
Sbjct: 17 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 76
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXX 453
+Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 77 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEK 136
Query: 454 XXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 137 VRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 177
Score = 68.9 bits (161), Expect = 4e-11
Identities = 85/421 (20%), Positives = 172/421 (40%), Gaps = 22/421 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + S+ RL+++I + D+E +++++ + + + ++ EE++
Sbjct: 15 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 74
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
ES + R TEL KL+ E+ LE ET K QE + D EQ+ KT
Sbjct: 75 LESSQKEARSLSTELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHE 133
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK + + +AE EL + +E R ++ +++ +IE R + +
Sbjct: 134 LEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---RKLAEKDEE 190
Query: 202 KQRLSQENIELVKEVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
++ + ++ +V +Q D + N + +K ++
Sbjct: 191 MEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQ 250
Query: 258 LHQVEIDLESVRVQLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXX 310
+ ++ L+ ++QL++ A DL ER+ E+ R+
Sbjct: 251 VKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKL 309
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARE 366
+ S +LI + ++ S+LQ+EVE + + EKA +
Sbjct: 310 ADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD 369
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALAR 425
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A R
Sbjct: 370 AAMMAEELKKEQ-DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 428
Query: 426 E 426
E
Sbjct: 429 E 429
Score = 67.3 bits (157), Expect = 1e-10
Identities = 70/416 (16%), Positives = 164/416 (39%), Gaps = 21/416 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + + L S + +E+ + L + ++L LEEAE E + + E
Sbjct: 113 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLE 172
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ +E E +E K+ + +V Q +D T+++ A + K K + ++ E
Sbjct: 173 FNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 232
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ Q+ + + K + L+ + + I++++ R D+ + + + N L E
Sbjct: 233 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 292
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + +++ DL ++ ++EE
Sbjct: 293 LEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 352
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ + E + KA + +
Sbjct: 353 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 412
Query: 336 INNVEKQKSRLQSEVEVLIIDLE---KANGTA----RELQKRTEQL------ERVNI--- 379
+ +KQ +L++ V L +LE K N + R+ ++R ++L +R N+
Sbjct: 413 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 472
Query: 380 -EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + ++ ++V HELD+ E+ D + K+
Sbjct: 473 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 528
Score = 53.6 bits (123), Expect = 2e-06
Identities = 33/171 (19%), Positives = 70/171 (40%), Gaps = 1/171 (0%)
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
H+++ ++E + V +E + A L+++ + + W+ K+
Sbjct: 27 HRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS-L 85
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
S + + +++ LQ E+ L L + T EL+K +QLE
Sbjct: 86 STELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEK 145
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+E++S LEE E + + Q E ++ E+++ +KD + K+
Sbjct: 146 MELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKR 196
Score = 52.8 bits (121), Expect = 3e-06
Identities = 57/332 (17%), Positives = 120/332 (36%), Gaps = 6/332 (1%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
E+T H L+ + +++++D +++ A +K++ F + E + E E +
Sbjct: 23 EKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 78
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLK 230
K L + +L EE + + L +E +L +++ I + ++
Sbjct: 79 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVR 138
Query: 231 SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
Q+ ++ + + +++ ++ ++E + A D E + K N
Sbjct: 139 KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKL-AEKDEEMEQAKRN 197
Query: 291 G-EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE 349
+ K +KQ LQS
Sbjct: 198 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 257
Query: 350 VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
++ I L+ A +L++ +ER N +++ LEE + EQT+R + EL
Sbjct: 258 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADRELIET 317
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARANI 441
S + Q +L + KKM DL + +
Sbjct: 318 SERVQLLHSQNTSLINQKKKMDADLSQLQTEV 349
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 82.2 bits (194), Expect = 4e-15
Identities = 44/161 (27%), Positives = 81/161 (50%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK +++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+ E
Sbjct: 5 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 64
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXX 453
+Q++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 65 SSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 124
Query: 454 XXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 125 VRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 165
Score = 68.1 bits (159), Expect = 7e-11
Identities = 84/418 (20%), Positives = 169/418 (40%), Gaps = 16/418 (3%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
VN + S+ RL+++I + D+E +++++ + + + ++ EE++
Sbjct: 3 VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSE 62
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
ES + R TEL KL+ E+ LE ET K QE + D EQ+ + K
Sbjct: 63 LESSQKEARSLSTELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHE 121
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
EK +++ + E EL + +E R ++ +++ +IE +
Sbjct: 122 LEKVRNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQ 181
Query: 202 KQRLSQENIELVKEVQDLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+R Q ++ ++ D + N V+ +K ++ +
Sbjct: 182 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 241
Query: 261 VEIDLESVRVQLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++ L+ ++QL++ A DL ER+ E+ R+
Sbjct: 242 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQ 300
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQK 369
+ S +LI + ++ S+LQSEVE + + EKA +
Sbjct: 301 ELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAM 360
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALARE 426
E+L++ + + LE + EQT +DL+++ E ++++ + K + QK +A RE
Sbjct: 361 MAEELKKEQ-DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 417
Score = 55.6 bits (128), Expect = 4e-07
Identities = 57/332 (17%), Positives = 125/332 (37%), Gaps = 6/332 (1%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
E+T H L+ + +++++D +++ A +K++ F + E + E E +
Sbjct: 11 EKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 66
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLK 230
K L + +L EE + + L +E +L +++ + N+ + ++
Sbjct: 67 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVR 126
Query: 231 SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
+Q+ + + + +++ ++ ++E + A D E + K N
Sbjct: 127 NQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER-NVAEKDEEMEQAKRN 185
Query: 291 GE-IGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE 349
+ + K +KQ LQS
Sbjct: 186 HQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 245
Query: 350 VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
++ I L+ A +L++ +ER N +++ LEE + EQT+R + + EL
Sbjct: 246 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 305
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARANI 441
S + Q +L + KKM DL ++ +
Sbjct: 306 SERVQLLHSQNTSLINQKKKMDADLSQLQSEV 337
Score = 36.7 bits (81), Expect = 0.19
Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 6/106 (5%)
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
N +E +K LQS +E LE G Q Q++ EI+ + E + EQ +
Sbjct: 127 NQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKA---EIERNVAEKDEEMEQAK 183
Query: 397 RDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
R N Q + + LD ++ + R KKM DL++ ++
Sbjct: 184 R---NHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLS 226
Score = 35.5 bits (78), Expect = 0.45
Identities = 28/131 (21%), Positives = 63/131 (48%), Gaps = 6/131 (4%)
Query: 42 LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL-LKLR 100
++ ++L+ E++ +ER K ++ + L RL+EAE + + +K+ +L ++R
Sbjct: 360 MMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAE---QIALKGGKKQLQKLEARVR 416
Query: 101 KLLEDVHLESEETAHLLK--KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA 158
+L ++ E + A +K +K++ + + Q ++ K R + +K Q +V
Sbjct: 417 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVNKLQLKVKAYKG 476
Query: 159 QVENVTKEKIT 169
Q E + T
Sbjct: 477 QAEEAEERANT 487
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 80.6 bits (190), Expect = 1e-14
Identities = 42/158 (26%), Positives = 79/158 (50%)
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
+++EK K RLQ+E+E L++D+E++N A L K+ +++ E K + EE+ E +Q
Sbjct: 1 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 60
Query: 397 RDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXX 456
++ R+ TEL ++ + +++ E + RENK + +++ D +
Sbjct: 61 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRK 120
Query: 457 XXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQFR 494
+A +EAEA + EE + R EF Q +
Sbjct: 121 QLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIK 158
Score = 68.5 bits (160), Expect = 5e-11
Identities = 82/408 (20%), Positives = 167/408 (40%), Gaps = 22/408 (5%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RL+++I + D+E +++++ + + + ++ EE++ ES + R T
Sbjct: 9 RLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLST 68
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
EL KL+ E+ LE ET K QE + D EQ+ KT EK + + +AE
Sbjct: 69 ELFKLKNAYEE-SLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKM 127
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL + +E R ++ +++ +IE R + + ++ + ++ +V
Sbjct: 128 ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---RNVAEKDEEMEQAKRNHLRVVD 184
Query: 215 EVQ---DLKVNIEN-VVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
+Q D + N + +K ++ + ++ L+ ++
Sbjct: 185 SLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQI 244
Query: 271 QLEEESEARLDL-------ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
QL++ A DL ER+ E+ R+ + S
Sbjct: 245 QLDDAVRANDDLKENIAIVERRNNLLQAELEELRA-VVEQTERSRKLAEQELIETSERVQ 303
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNI 379
+LI + ++ S+LQ+EVE + + EKA + E+L++
Sbjct: 304 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ- 362
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK-DALARE 426
+ + LE + EQT +DL+++ E ++++ + K + QK +A RE
Sbjct: 363 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 410
Score = 67.7 bits (158), Expect = 9e-11
Identities = 70/416 (16%), Positives = 164/416 (39%), Gaps = 21/416 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+++I + + L S + +E+ + L + ++L LEEAE E + + E
Sbjct: 94 LQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLE 153
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ +E E +E K+ + +V Q +D T+++ A + K K + ++ E
Sbjct: 154 FNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNE 213
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ Q+ + + K + L+ + + I++++ R D+ + + + N L E
Sbjct: 214 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 273
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+++L+ +E + + +++ DL ++ ++EE
Sbjct: 274 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 333
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+ + E + KA + +
Sbjct: 334 VQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 393
Query: 336 INNVEKQKSRLQSEVEVLIIDLE---KANGTA----RELQKRTEQL------ERVNI--- 379
+ +KQ +L++ V L +LE K N + R+ ++R ++L +R N+
Sbjct: 394 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 453
Query: 380 -EIKSRLEETVQLY----EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++ +L+ V+ Y E+ + ++ ++V HELD+ E+ D + K+
Sbjct: 454 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 509
Score = 53.6 bits (123), Expect = 2e-06
Identities = 57/332 (17%), Positives = 121/332 (36%), Gaps = 6/332 (1%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
E+T H L+ + +++++D +++ A +K++ F + E + E E +
Sbjct: 4 EKTKHRLQNEIEDLMVD----VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 59
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLK 230
K L + +L EE + + L +E +L +++ I + ++
Sbjct: 60 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVR 119
Query: 231 SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKAN 290
Q+ ++ + + +++ ++ ++E + A D E + K N
Sbjct: 120 KQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER-NVAEKDEEMEQAKRN 178
Query: 291 G-EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE 349
+ K +KQ LQS
Sbjct: 179 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 238
Query: 350 VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
++ I L+ A +L++ +ER N +++ LEE + EQT+R + + EL
Sbjct: 239 LKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIET 298
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARANI 441
S + Q +L + KKM DL + +
Sbjct: 299 SERVQLLHSQNTSLINQKKKMDADLSQLQTEV 330
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/198 (21%), Positives = 99/198 (50%), Gaps = 10/198 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ K++ ++ LE E E +Q++ REK +L ++ LS+++ + FE ++ +L
Sbjct: 1618 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD------FESEKRLRKDL 1671
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ + LL D L + + K + + + Q+++ T A A K + + E+ +L
Sbjct: 1672 KRTKALLADAQLMLDHLKNSAPSKRE--IAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1729
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
Q++++ K K + + RL+ +E+ ++EE + ++ HK ++Q + +L +
Sbjct: 1730 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA-Q 1788
Query: 216 VQDLKVNIENVVYLKSQI 233
+ DL+ +E K ++
Sbjct: 1789 INDLQAQLEEANKEKQEL 1806
Score = 52.8 bits (121), Expect = 3e-06
Identities = 75/417 (17%), Positives = 184/417 (44%), Gaps = 31/417 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINRKR 92
R + ++ ++ + E+ R++++REK L + L ++LEE + +Q ++ +
Sbjct: 1475 RFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA 1534
Query: 93 DTELLKLRKLLEDVHLE--SEETAHL-LKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSK 148
+ + + ++ ++ L ++ L K K+QE +D Q I L + K R E E +
Sbjct: 1535 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMER 1594
Query: 149 F-QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNR----------TIVD 197
Q E+ ++ E V + + + K +++E+ + E + +++ R T+ D
Sbjct: 1595 MRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1654
Query: 198 ITSHKQRLSQENIEL-VKEVQDLKVNIENVV-YLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ + S++ + +K + L + + ++ +LK+ S+
Sbjct: 1655 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1714
Query: 256 A--SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
A + +E+++E + +Q+++ ++A+ LE QL + E +++
Sbjct: 1715 AVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK 1774
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ L A++ K+K LQ +++ L +E + + + Q
Sbjct: 1775 HKAAVA-QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1833
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD-ALARENKK 429
++ E+++RLE +E+TQ ++ ++ R+ ++K E++D +A EN++
Sbjct: 1834 EAKIR-ELETRLE-----FERTQ--VKRLESLASRLKENMEKLTEERDQRIAAENRE 1882
Score = 49.2 bits (112), Expect = 3e-05
Identities = 74/405 (18%), Positives = 156/405 (38%), Gaps = 28/405 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE +++ I + +++++ DL +V E L+E G + + + + E
Sbjct: 1532 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEME 1591
Query: 96 LLKLR----KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+ ++R K +E E EE +KK +++ + +E+ + K + +EK + +
Sbjct: 1592 MERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED----KQKVLREKRELEG 1647
Query: 152 EVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV---DITSHKQRLSQ 207
++ L QV E + + K +R + +++ + ++ L + +I K +L +
Sbjct: 1648 KLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE 1707
Query: 208 ENIEL---VK-------EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
VK E++DL + I+++ K+ + Q
Sbjct: 1708 SEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED 1767
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
++++ ++ Q + DL+ QL +AN E + K K
Sbjct: 1768 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDK 1827
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L ++ Q RL+S L ++EK R+ + E E+
Sbjct: 1828 --SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-EERDQRIAAENREK- 1883
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA 422
E RL+ ++ ++ +L K+ E R HEL+ E +A
Sbjct: 1884 --EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1926
Score = 42.3 bits (95), Expect = 0.004
Identities = 69/421 (16%), Positives = 165/421 (39%), Gaps = 29/421 (6%)
Query: 49 SERELRQRIEREKADLSVQ-VIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-- 105
+++ L+Q E +K ++ Q QL RL + + +E ++ + +L L+D
Sbjct: 1398 TKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTK 1456
Query: 106 VHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVE 161
+HLE ++ H L+KK + + + ++ + K + EK EK AE + L Q+E
Sbjct: 1457 LHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1516
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ LE + ++ + + ++ + + L + + +E+ +
Sbjct: 1517 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1576
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ-VEIDLESVRVQLEEESE--- 277
I+ + K ++ + Q + L+ + VQLEEE E
Sbjct: 1577 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQ 1636
Query: 278 ----ARLDLERQLVKANGEIGH--WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
+ +LE +L + ++ + S+ +
Sbjct: 1637 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1696
Query: 332 LIAKINN-----------VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
IA++ N K + ++ E+E L + ++ L+++ +L+R E
Sbjct: 1697 EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNE 1756
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
I++RLEE + + + + + R +++ + Q + +E +++ + L ++
Sbjct: 1757 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1816
Query: 441 I 441
+
Sbjct: 1817 V 1817
Score = 38.7 bits (86), Expect = 0.048
Identities = 27/99 (27%), Positives = 47/99 (47%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+Q E++ L LEKA EL+ +++LE E+ S L + E + L
Sbjct: 1266 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1325
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ E R E+ + + Q DAL ++ + M ++ +AR
Sbjct: 1326 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1364
Score = 38.3 bits (85), Expect = 0.064
Identities = 43/242 (17%), Positives = 99/242 (40%), Gaps = 11/242 (4%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
L++E R R E+E +L Q L +++E E E+ R L++ ++ +V
Sbjct: 1325 LDAETAERLRAEKEMKELQTQYDALKKQMEVME------MEVMEAR---LIRAAEINGEV 1375
Query: 107 HLESEETAHLLKKKNQEIVIDF-QEQIDQLTKTKARAEKE-KSKFQAEVYELLAQVENVT 164
+ LK + +DF ++++ Q + K E++ K + + + +L A E
Sbjct: 1376 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQ 1435
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ + K C+RL + + + +E ++ ++R E + +E Q K+ E
Sbjct: 1436 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1495
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLER 284
+ K + ++ + +E +L+ + Q ++ + +++
Sbjct: 1496 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1555
Query: 285 QL 286
QL
Sbjct: 1556 QL 1557
Score = 37.1 bits (82), Expect = 0.15
Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 11/175 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DD ++ E R + ER ++ +L + E+ + + E KR E +L L
Sbjct: 1376 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-----KLEVEQQNKRQLER-RLGDLQA 1429
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D ES+ LKKK Q + + Q+ L + R + + K + EL E
Sbjct: 1430 DSE-ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1488
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
+EK+ K ++ ++E ++L +DI Q++ + L E+QD+
Sbjct: 1489 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV----VSLEAELQDI 1539
Score = 37.1 bits (82), Expect = 0.15
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
D S +SR E KIR ++ LE ER +R+E + L + +L+E ++ + E
Sbjct: 1826 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1885
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR-AEKEKS 147
N++ +L ++ + ++ + E + KK E+ ++ E +Q + + A K
Sbjct: 1886 NKRLQRQLRDTKEEMGELARKEAEASR--KKHELEMDLESLEAANQSLQADLKLAFKRIG 1943
Query: 148 KFQAEVYELLAQVEN 162
QA + + + EN
Sbjct: 1944 DLQAAIEDEMESDEN 1958
>BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein.
Length = 2002
Score = 65.3 bits (152), Expect = 5e-10
Identities = 50/233 (21%), Positives = 110/233 (47%), Gaps = 12/233 (5%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREK 61
+++AK K R D E + LE +++ ++ LE E E +Q++ REK
Sbjct: 1535 ASLAKVKKQL-RDLEAKVKDQEEELDEQAGTIQMLE-QLKQMEVQLEEEYEDKQKVLREK 1592
Query: 62 ADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKN 121
+L ++ LS+++ + FE ++ +L + + LL D L + + K
Sbjct: 1593 RELEGKLATLSDQVNRRD------FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1646
Query: 122 QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITI 181
+ + + Q+++ T A A K + + E+ +L Q++++ K K + + RL+
Sbjct: 1647 E--IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1704
Query: 182 SELHIKIEELNRTIVDI-TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
+E+ ++EE + ++ HK ++Q + +L ++ DL+ +E K ++
Sbjct: 1705 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA-QINDLQAQLEEANKEKQEL 1756
Score = 54.4 bits (125), Expect = 9e-07
Identities = 73/399 (18%), Positives = 172/399 (43%), Gaps = 32/399 (8%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + ++ ++ + E+ R++++REK L + L ++LEE + +
Sbjct: 1462 RFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ------- 1514
Query: 95 ELLKLRKLLEDV-HLESEETAHLLKKKNQ--EIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+++ L L+D+ ES++ A L K K Q ++ ++Q ++L + + + Q
Sbjct: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQLKQM 1574
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
EV Q+E ++K + + LE ++ L +++NR + ++ +
Sbjct: 1575 EV-----QLEEEYEDKQKVLREKRELEGKLATLS---DQVNRRDFESEKRLRKDLKRTKA 1626
Query: 212 LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
L+ + Q + +++N K +IA A +E+++E + +Q
Sbjct: 1627 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKA----MEVEIEDLHLQ 1682
Query: 272 LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
+++ ++A+ LE QL + E +++ +
Sbjct: 1683 IDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA-QASRDLAQIND 1741
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L A++ K+K LQ +++ L +E + + + Q ++ E+++RLE
Sbjct: 1742 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIR-ELETRLE----- 1795
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKD-ALARENKK 429
+E+TQ ++ ++ R+ ++K E++D +A EN++
Sbjct: 1796 FERTQ--VKRLESLASRLKENMEKLTEERDQRIAAENRE 1832
Score = 46.0 bits (104), Expect = 3e-04
Identities = 77/404 (19%), Positives = 163/404 (40%), Gaps = 27/404 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DD ++ E R + ER ++ +L + E+ + + E KR E +L L
Sbjct: 1363 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-----KLEVEQQNKRQLER-RLGDLQA 1416
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D ES+ LKKK Q + + Q+ L + R + + K + EL E
Sbjct: 1417 DSE-ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1475
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+EK+ K ++ ++E ++L +DI Q++ + L E+QD+
Sbjct: 1476 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV----VSLEAELQDISSQES 1531
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLER 284
+++ Q ++ +E L+ + VQLEEE E + + R
Sbjct: 1532 KDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLE-QLKQMEVQLEEEYEDKQKVLR 1590
Query: 285 QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKS 344
+ + G++ + K ++ + N K
Sbjct: 1591 EKRELEGKL----ATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1646
Query: 345 RLQSEVEVLIIDLEKANGTARELQKRTE-QLERVNIEI------KSRLEETVQLYEQTQR 397
+ ++++ + + E A + +K E ++E ++++I K+ LEE + ++ +
Sbjct: 1647 EI-AQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1705
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+++N+ E Q +EL K + K A+A+ ++ + ++D +A +
Sbjct: 1706 EIQNRLEEDQEDMNELMK--KHKAAVAQASRDLA-QINDLQAQL 1746
Score = 38.7 bits (86), Expect = 0.048
Identities = 27/99 (27%), Positives = 47/99 (47%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+Q E++ L LEKA EL+ +++LE E+ S L + E + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ E R E+ + + Q DAL ++ + M ++ +AR
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1351
Score = 37.1 bits (82), Expect = 0.15
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
D S +SR E KIR ++ LE ER +R+E + L + +L+E ++ + E
Sbjct: 1776 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1835
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR-AEKEKS 147
N++ +L ++ + ++ + E + KK E+ ++ E +Q + + A K
Sbjct: 1836 NKRLQRQLRDTKEEMGELARKEAEASR--KKHELEMDLESLEAANQSLQADLKLAFKRIG 1893
Query: 148 KFQAEVYELLAQVEN 162
QA + + + EN
Sbjct: 1894 DLQAAIEDEMESDEN 1908
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/198 (21%), Positives = 99/198 (50%), Gaps = 10/198 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ K++ ++ LE E E +Q++ REK +L ++ LS+++ + FE ++ +L
Sbjct: 1147 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD------FESEKRLRKDL 1200
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ + LL D L + + K + + + Q+++ T A A K + + E+ +L
Sbjct: 1201 KRTKALLADAQLMLDHLKNSAPSKRE--IAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1258
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
Q++++ K K + + RL+ +E+ ++EE + ++ HK ++Q + +L +
Sbjct: 1259 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA-Q 1317
Query: 216 VQDLKVNIENVVYLKSQI 233
+ DL+ +E K ++
Sbjct: 1318 INDLQAQLEEANKEKQEL 1335
Score = 52.8 bits (121), Expect = 3e-06
Identities = 75/417 (17%), Positives = 184/417 (44%), Gaps = 31/417 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINRKR 92
R + ++ ++ + E+ R++++REK L + L ++LEE + +Q ++ +
Sbjct: 1004 RFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA 1063
Query: 93 DTELLKLRKLLEDVHLE--SEETAHL-LKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSK 148
+ + + ++ ++ L ++ L K K+QE +D Q I L + K R E E +
Sbjct: 1064 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMER 1123
Query: 149 F-QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNR----------TIVD 197
Q E+ ++ E V + + + K +++E+ + E + +++ R T+ D
Sbjct: 1124 MRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1183
Query: 198 ITSHKQRLSQENIEL-VKEVQDLKVNIENVV-YLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ + S++ + +K + L + + ++ +LK+ S+
Sbjct: 1184 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1243
Query: 256 A--SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
A + +E+++E + +Q+++ ++A+ LE QL + E +++
Sbjct: 1244 AVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK 1303
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ L A++ K+K LQ +++ L +E + + + Q
Sbjct: 1304 HKAAVA-QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1362
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD-ALARENKK 429
++ E+++RLE +E+TQ ++ ++ R+ ++K E++D +A EN++
Sbjct: 1363 EAKIR-ELETRLE-----FERTQ--VKRLESLASRLKENMEKLTEERDQRIAAENRE 1411
Score = 49.2 bits (112), Expect = 3e-05
Identities = 74/405 (18%), Positives = 156/405 (38%), Gaps = 28/405 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE +++ I + +++++ DL +V E L+E G + + + + E
Sbjct: 1061 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEME 1120
Query: 96 LLKLR----KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+ ++R K +E E EE +KK +++ + +E+ + K + +EK + +
Sbjct: 1121 MERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED----KQKVLREKRELEG 1176
Query: 152 EVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV---DITSHKQRLSQ 207
++ L QV E + + K +R + +++ + ++ L + +I K +L +
Sbjct: 1177 KLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE 1236
Query: 208 ENIEL---VK-------EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
VK E++DL + I+++ K+ + Q
Sbjct: 1237 SEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED 1296
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
++++ ++ Q + DL+ QL +AN E + K K
Sbjct: 1297 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDK 1356
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L ++ Q RL+S L ++EK R+ + E E+
Sbjct: 1357 --SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-EERDQRIAAENREK- 1412
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA 422
E RL+ ++ ++ +L K+ E R HEL+ E +A
Sbjct: 1413 --EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1455
Score = 42.3 bits (95), Expect = 0.004
Identities = 69/421 (16%), Positives = 165/421 (39%), Gaps = 29/421 (6%)
Query: 49 SERELRQRIEREKADLSVQ-VIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-- 105
+++ L+Q E +K ++ Q QL RL + + +E ++ + +L L+D
Sbjct: 927 TKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTK 985
Query: 106 VHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVE 161
+HLE ++ H L+KK + + + ++ + K + EK EK AE + L Q+E
Sbjct: 986 LHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1045
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ LE + ++ + + ++ + + L + + +E+ +
Sbjct: 1046 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1105
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ-VEIDLESVRVQLEEESE--- 277
I+ + K ++ + Q + L+ + VQLEEE E
Sbjct: 1106 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQ 1165
Query: 278 ----ARLDLERQLVKANGEIGH--WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
+ +LE +L + ++ + S+ +
Sbjct: 1166 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1225
Query: 332 LIAKINN-----------VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
IA++ N K + ++ E+E L + ++ L+++ +L+R E
Sbjct: 1226 EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNE 1285
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
I++RLEE + + + + + R +++ + Q + +E +++ + L ++
Sbjct: 1286 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1345
Query: 441 I 441
+
Sbjct: 1346 V 1346
Score = 38.7 bits (86), Expect = 0.048
Identities = 27/99 (27%), Positives = 47/99 (47%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+Q E++ L LEKA EL+ +++LE E+ S L + E + L
Sbjct: 795 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 854
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ E R E+ + + Q DAL ++ + M ++ +AR
Sbjct: 855 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 893
Score = 38.3 bits (85), Expect = 0.064
Identities = 43/242 (17%), Positives = 99/242 (40%), Gaps = 11/242 (4%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
L++E R R E+E +L Q L +++E E E+ R L++ ++ +V
Sbjct: 854 LDAETAERLRAEKEMKELQTQYDALKKQMEVME------MEVMEAR---LIRAAEINGEV 904
Query: 107 HLESEETAHLLKKKNQEIVIDF-QEQIDQLTKTKARAEKE-KSKFQAEVYELLAQVENVT 164
+ LK + +DF ++++ Q + K E++ K + + + +L A E
Sbjct: 905 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQ 964
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ + K C+RL + + + +E ++ ++R E + +E Q K+ E
Sbjct: 965 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1024
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLER 284
+ K + ++ + +E +L+ + Q ++ + +++
Sbjct: 1025 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1084
Query: 285 QL 286
QL
Sbjct: 1085 QL 1086
Score = 37.1 bits (82), Expect = 0.15
Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 11/175 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DD ++ E R + ER ++ +L + E+ + + E KR E +L L
Sbjct: 905 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-----KLEVEQQNKRQLER-RLGDLQA 958
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D ES+ LKKK Q + + Q+ L + R + + K + EL E
Sbjct: 959 DSE-ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1017
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
+EK+ K ++ ++E ++L +DI Q++ + L E+QD+
Sbjct: 1018 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV----VSLEAELQDI 1068
Score = 37.1 bits (82), Expect = 0.15
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
D S +SR E KIR ++ LE ER +R+E + L + +L+E ++ + E
Sbjct: 1355 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1414
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR-AEKEKS 147
N++ +L ++ + ++ + E + KK E+ ++ E +Q + + A K
Sbjct: 1415 NKRLQRQLRDTKEEMGELARKEAEASR--KKHELEMDLESLEAANQSLQADLKLAFKRIG 1472
Query: 148 KFQAEVYELLAQVEN 162
QA + + + EN
Sbjct: 1473 DLQAAIEDEMESDEN 1487
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/198 (21%), Positives = 99/198 (50%), Gaps = 10/198 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ K++ ++ LE E E +Q++ REK +L ++ LS+++ + FE ++ +L
Sbjct: 1281 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD------FESEKRLRKDL 1334
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ + LL D L + + K + + + Q+++ T A A K + + E+ +L
Sbjct: 1335 KRTKALLADAQLMLDHLKNSAPSKRE--IAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1392
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
Q++++ K K + + RL+ +E+ ++EE + ++ HK ++Q + +L +
Sbjct: 1393 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA-Q 1451
Query: 216 VQDLKVNIENVVYLKSQI 233
+ DL+ +E K ++
Sbjct: 1452 INDLQAQLEEANKEKQEL 1469
Score = 52.8 bits (121), Expect = 3e-06
Identities = 75/417 (17%), Positives = 184/417 (44%), Gaps = 31/417 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINRKR 92
R + ++ ++ + E+ R++++REK L + L ++LEE + +Q ++ +
Sbjct: 1138 RFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA 1197
Query: 93 DTELLKLRKLLEDVHLE--SEETAHL-LKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSK 148
+ + + ++ ++ L ++ L K K+QE +D Q I L + K R E E +
Sbjct: 1198 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMER 1257
Query: 149 F-QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNR----------TIVD 197
Q E+ ++ E V + + + K +++E+ + E + +++ R T+ D
Sbjct: 1258 MRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1317
Query: 198 ITSHKQRLSQENIEL-VKEVQDLKVNIENVV-YLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ + S++ + +K + L + + ++ +LK+ S+
Sbjct: 1318 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1377
Query: 256 A--SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
A + +E+++E + +Q+++ ++A+ LE QL + E +++
Sbjct: 1378 AVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK 1437
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ L A++ K+K LQ +++ L +E + + + Q
Sbjct: 1438 HKAAVA-QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1496
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD-ALARENKK 429
++ E+++RLE +E+TQ ++ ++ R+ ++K E++D +A EN++
Sbjct: 1497 EAKIR-ELETRLE-----FERTQ--VKRLESLASRLKENMEKLTEERDQRIAAENRE 1545
Score = 49.2 bits (112), Expect = 3e-05
Identities = 74/405 (18%), Positives = 156/405 (38%), Gaps = 28/405 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE +++ I + +++++ DL +V E L+E G + + + + E
Sbjct: 1195 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEME 1254
Query: 96 LLKLR----KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+ ++R K +E E EE +KK +++ + +E+ + K + +EK + +
Sbjct: 1255 MERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED----KQKVLREKRELEG 1310
Query: 152 EVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV---DITSHKQRLSQ 207
++ L QV E + + K +R + +++ + ++ L + +I K +L +
Sbjct: 1311 KLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE 1370
Query: 208 ENIEL---VK-------EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
VK E++DL + I+++ K+ + Q
Sbjct: 1371 SEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED 1430
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
++++ ++ Q + DL+ QL +AN E + K K
Sbjct: 1431 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDK 1490
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L ++ Q RL+S L ++EK R+ + E E+
Sbjct: 1491 --SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-EERDQRIAAENREK- 1546
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA 422
E RL+ ++ ++ +L K+ E R HEL+ E +A
Sbjct: 1547 --EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1589
Score = 42.3 bits (95), Expect = 0.004
Identities = 69/421 (16%), Positives = 165/421 (39%), Gaps = 29/421 (6%)
Query: 49 SERELRQRIEREKADLSVQ-VIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-- 105
+++ L+Q E +K ++ Q QL RL + + +E ++ + +L L+D
Sbjct: 1061 TKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTK 1119
Query: 106 VHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVE 161
+HLE ++ H L+KK + + + ++ + K + EK EK AE + L Q+E
Sbjct: 1120 LHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1179
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ LE + ++ + + ++ + + L + + +E+ +
Sbjct: 1180 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1239
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ-VEIDLESVRVQLEEESE--- 277
I+ + K ++ + Q + L+ + VQLEEE E
Sbjct: 1240 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQ 1299
Query: 278 ----ARLDLERQLVKANGEIGH--WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
+ +LE +L + ++ + S+ +
Sbjct: 1300 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1359
Query: 332 LIAKINN-----------VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
IA++ N K + ++ E+E L + ++ L+++ +L+R E
Sbjct: 1360 EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNE 1419
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
I++RLEE + + + + + R +++ + Q + +E +++ + L ++
Sbjct: 1420 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1479
Query: 441 I 441
+
Sbjct: 1480 V 1480
Score = 38.7 bits (86), Expect = 0.048
Identities = 27/99 (27%), Positives = 47/99 (47%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+Q E++ L LEKA EL+ +++LE E+ S L + E + L
Sbjct: 929 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 988
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ E R E+ + + Q DAL ++ + M ++ +AR
Sbjct: 989 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1027
Score = 38.3 bits (85), Expect = 0.064
Identities = 43/242 (17%), Positives = 99/242 (40%), Gaps = 11/242 (4%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
L++E R R E+E +L Q L +++E E E+ R L++ ++ +V
Sbjct: 988 LDAETAERLRAEKEMKELQTQYDALKKQMEVME------MEVMEAR---LIRAAEINGEV 1038
Query: 107 HLESEETAHLLKKKNQEIVIDF-QEQIDQLTKTKARAEKE-KSKFQAEVYELLAQVENVT 164
+ LK + +DF ++++ Q + K E++ K + + + +L A E
Sbjct: 1039 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQ 1098
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ + K C+RL + + + +E ++ ++R E + +E Q K+ E
Sbjct: 1099 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1158
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLER 284
+ K + ++ + +E +L+ + Q ++ + +++
Sbjct: 1159 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1218
Query: 285 QL 286
QL
Sbjct: 1219 QL 1220
Score = 37.1 bits (82), Expect = 0.15
Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 11/175 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DD ++ E R + ER ++ +L + E+ + + E KR E +L L
Sbjct: 1039 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-----KLEVEQQNKRQLER-RLGDLQA 1092
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D ES+ LKKK Q + + Q+ L + R + + K + EL E
Sbjct: 1093 DSE-ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1151
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
+EK+ K ++ ++E ++L +DI Q++ + L E+QD+
Sbjct: 1152 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV----VSLEAELQDI 1202
Score = 37.1 bits (82), Expect = 0.15
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
D S +SR E KIR ++ LE ER +R+E + L + +L+E ++ + E
Sbjct: 1489 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1548
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR-AEKEKS 147
N++ +L ++ + ++ + E + KK E+ ++ E +Q + + A K
Sbjct: 1549 NKRLQRQLRDTKEEMGELARKEAEASR--KKHELEMDLESLEAANQSLQADLKLAFKRIG 1606
Query: 148 KFQAEVYELLAQVEN 162
QA + + + EN
Sbjct: 1607 DLQAAIEDEMESDEN 1621
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 65.3 bits (152), Expect = 5e-10
Identities = 43/198 (21%), Positives = 99/198 (50%), Gaps = 10/198 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ K++ ++ LE E E +Q++ REK +L ++ LS+++ + FE ++ +L
Sbjct: 1597 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRD------FESEKRLRKDL 1650
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ + LL D L + + K + + + Q+++ T A A K + + E+ +L
Sbjct: 1651 KRTKALLADAQLMLDHLKNSAPSKRE--IAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1708
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
Q++++ K K + + RL+ +E+ ++EE + ++ HK ++Q + +L +
Sbjct: 1709 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLA-Q 1767
Query: 216 VQDLKVNIENVVYLKSQI 233
+ DL+ +E K ++
Sbjct: 1768 INDLQAQLEEANKEKQEL 1785
Score = 52.8 bits (121), Expect = 3e-06
Identities = 75/417 (17%), Positives = 184/417 (44%), Gaps = 31/417 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINRKR 92
R + ++ ++ + E+ R++++REK L + L ++LEE + +Q ++ +
Sbjct: 1454 RFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA 1513
Query: 93 DTELLKLRKLLEDVHLE--SEETAHL-LKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSK 148
+ + + ++ ++ L ++ L K K+QE +D Q I L + K R E E +
Sbjct: 1514 ELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMER 1573
Query: 149 F-QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNR----------TIVD 197
Q E+ ++ E V + + + K +++E+ + E + +++ R T+ D
Sbjct: 1574 MRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1633
Query: 198 ITSHKQRLSQENIEL-VKEVQDLKVNIENVV-YLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+ + S++ + +K + L + + ++ +LK+ S+
Sbjct: 1634 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1693
Query: 256 A--SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
A + +E+++E + +Q+++ ++A+ LE QL + E +++
Sbjct: 1694 AVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK 1753
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ L A++ K+K LQ +++ L +E + + + Q
Sbjct: 1754 HKAAVA-QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ 1812
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD-ALARENKK 429
++ E+++RLE +E+TQ ++ ++ R+ ++K E++D +A EN++
Sbjct: 1813 EAKIR-ELETRLE-----FERTQ--VKRLESLASRLKENMEKLTEERDQRIAAENRE 1861
Score = 49.2 bits (112), Expect = 3e-05
Identities = 74/405 (18%), Positives = 156/405 (38%), Gaps = 28/405 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE +++ I + +++++ DL +V E L+E G + + + + E
Sbjct: 1511 LEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEME 1570
Query: 96 LLKLR----KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+ ++R K +E E EE +KK +++ + +E+ + K + +EK + +
Sbjct: 1571 MERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED----KQKVLREKRELEG 1626
Query: 152 EVYELLAQVENVTKE-KITISKTCERLEITISELHIKIEELNRTIV---DITSHKQRLSQ 207
++ L QV E + + K +R + +++ + ++ L + +I K +L +
Sbjct: 1627 KLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEE 1686
Query: 208 ENIEL---VK-------EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
VK E++DL + I+++ K+ + Q
Sbjct: 1687 SEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED 1746
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
++++ ++ Q + DL+ QL +AN E + K K
Sbjct: 1747 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDK 1806
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L ++ Q RL+S L ++EK R+ + E E+
Sbjct: 1807 --SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLT-EERDQRIAAENREK- 1862
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA 422
E RL+ ++ ++ +L K+ E R HEL+ E +A
Sbjct: 1863 --EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1905
Score = 42.3 bits (95), Expect = 0.004
Identities = 69/421 (16%), Positives = 165/421 (39%), Gaps = 29/421 (6%)
Query: 49 SERELRQRIEREKADLSVQ-VIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED-- 105
+++ L+Q E +K ++ Q QL RL + + +E ++ + +L L+D
Sbjct: 1377 TKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTK 1435
Query: 106 VHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVE 161
+HLE ++ H L+KK + + + ++ + K + EK EK AE + L Q+E
Sbjct: 1436 LHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLE 1495
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ LE + ++ + + ++ + + L + + +E+ +
Sbjct: 1496 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1555
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ-VEIDLESVRVQLEEESE--- 277
I+ + K ++ + Q + L+ + VQLEEE E
Sbjct: 1556 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQ 1615
Query: 278 ----ARLDLERQLVKANGEIGH--WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXT 331
+ +LE +L + ++ + S+ +
Sbjct: 1616 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR 1675
Query: 332 LIAKINN-----------VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
IA++ N K + ++ E+E L + ++ L+++ +L+R E
Sbjct: 1676 EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNE 1735
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
I++RLEE + + + + + R +++ + Q + +E +++ + L ++
Sbjct: 1736 IQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQ 1795
Query: 441 I 441
+
Sbjct: 1796 V 1796
Score = 38.7 bits (86), Expect = 0.048
Identities = 27/99 (27%), Positives = 47/99 (47%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+Q E++ L LEKA EL+ +++LE E+ S L + E + L
Sbjct: 1245 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1304
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
+ E R E+ + + Q DAL ++ + M ++ +AR
Sbjct: 1305 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEAR 1343
Score = 38.3 bits (85), Expect = 0.064
Identities = 43/242 (17%), Positives = 99/242 (40%), Gaps = 11/242 (4%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
L++E R R E+E +L Q L +++E E E+ R L++ ++ +V
Sbjct: 1304 LDAETAERLRAEKEMKELQTQYDALKKQMEVME------MEVMEAR---LIRAAEINGEV 1354
Query: 107 HLESEETAHLLKKKNQEIVIDF-QEQIDQLTKTKARAEKE-KSKFQAEVYELLAQVENVT 164
+ LK + +DF ++++ Q + K E++ K + + + +L A E
Sbjct: 1355 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQ 1414
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ + K C+RL + + + +E ++ ++R E + +E Q K+ E
Sbjct: 1415 RALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQRE 1474
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLER 284
+ K + ++ + +E +L+ + Q ++ + +++
Sbjct: 1475 KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKK 1534
Query: 285 QL 286
QL
Sbjct: 1535 QL 1536
Score = 37.1 bits (82), Expect = 0.15
Identities = 41/175 (23%), Positives = 74/175 (42%), Gaps = 11/175 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
DD ++ E R + ER ++ +L + E+ + + E KR E +L L
Sbjct: 1355 DDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-----KLEVEQQNKRQLER-RLGDLQA 1408
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
D ES+ LKKK Q + + Q+ L + R + + K + EL E
Sbjct: 1409 DSE-ESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1467
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
+EK+ K ++ ++E ++L +DI Q++ + L E+QD+
Sbjct: 1468 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV----VSLEAELQDI 1518
Score = 37.1 bits (82), Expect = 0.15
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 3/135 (2%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
D S +SR E KIR ++ LE ER +R+E + L + +L+E ++ + E
Sbjct: 1805 DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQ 1864
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR-AEKEKS 147
N++ +L ++ + ++ + E + KK E+ ++ E +Q + + A K
Sbjct: 1865 NKRLQRQLRDTKEEMGELARKEAEASR--KKHELEMDLESLEAANQSLQADLKLAFKRIG 1922
Query: 148 KFQAEVYELLAQVEN 162
QA + + + EN
Sbjct: 1923 DLQAAIEDEMESDEN 1937
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 64.5 bits (150), Expect = 8e-10
Identities = 76/461 (16%), Positives = 171/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 46 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 104
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 105 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 164
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 165 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 223
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 224 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 283
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + + + K ++ ++ + L
Sbjct: 284 DSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 342
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 343 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 402
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 403 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 462
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 463 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 501
Score = 61.7 bits (143), Expect = 6e-09
Identities = 37/166 (22%), Positives = 75/166 (45%), Gaps = 1/166 (0%)
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QL EE EA+ +LER + N ++ + K ++
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK-RFQKEIENLTQQYE 59
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 60 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 119
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 165
Score = 56.0 bits (129), Expect = 3e-07
Identities = 84/417 (20%), Positives = 158/417 (37%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 187 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 246
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K K QA++
Sbjct: 247 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMK 305
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 306 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 365
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 366 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 422
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 423 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 463
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 464 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 521
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 522 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 578
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 383 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 442
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 443 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 502
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 503 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 556
Score = 40.7 bits (91), Expect = 0.012
Identities = 42/251 (16%), Positives = 99/251 (39%), Gaps = 5/251 (1%)
Query: 190 ELNRTIVDITSHKQRLSQENIELV---KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXX 246
+LN + + ++ +S NI+L K++QD +E + K + +
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE 60
Query: 247 XXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXX 306
+ ++++ +L+ + V L+ + + +LE++ K + + ++
Sbjct: 61 KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 120
Query: 307 XXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE 366
K + L AK +E+ L++E+E L+ + E
Sbjct: 121 RDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARE 426
L+K LE E+K++LEE + T+ + +Q + + ++ + +D E
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 427 NKK-MGDDLHD 436
++ + LH+
Sbjct: 240 KRRQLQRQLHE 250
Score = 34.7 bits (76), Expect = 0.79
Identities = 46/312 (14%), Positives = 114/312 (36%), Gaps = 5/312 (1%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHI 186
D ++++ T E+ K +FQ E+ L Q E + KT RL+ + +L +
Sbjct: 25 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 84
Query: 187 KIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS-QIASQXXXXXXXXX 245
++ R +V KQR + + K + + + ++ + ++
Sbjct: 85 DLDN-QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 143
Query: 246 XXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXX 305
+ ++ ++E + ++ + +LE+ ++ +++
Sbjct: 144 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 203
Query: 306 XXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
L A+ E+++ +LQ ++ +LE
Sbjct: 204 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 263
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD---A 422
++LE +++ + + ++ E+ + +R Q +++ EL+ R +D A
Sbjct: 264 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFA 323
Query: 423 LARENKKMGDDL 434
A+EN+K L
Sbjct: 324 TAKENEKKAKSL 335
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 486 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 545
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 546 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 583
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 464 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 523
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 524 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 557
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 64.5 bits (150), Expect = 8e-10
Identities = 76/461 (16%), Positives = 171/461 (37%), Gaps = 14/461 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R + +I + E + ++E+ K L ++ L L+ + S E +++
Sbjct: 46 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN-QRQLVSNLEKKQRKFD 104
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LL K + + + + A ++ + + +++ + K E+ +AE+
Sbjct: 105 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 164
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+L++ ++V K + K+ LE + E+ ++EEL + K RL + N++ +K
Sbjct: 165 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALK 223
Query: 215 EV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+DL+ E + Q+ Q A+ ++E DL+ + +Q
Sbjct: 224 GQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQA 283
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+ + R + + + K ++ ++ + L
Sbjct: 284 DSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKEN-EKKAKSLEADLMQL 342
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ E+ + + E E L +L + LQ +LE +++ LEE
Sbjct: 343 QEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNM 402
Query: 393 EQTQRDLRNKQTELQRVSHEL-------DKTREQKDALARENKKMGDDLHDARANITXXX 445
E +R + +++S+EL K + L R+NK++ LH+ +
Sbjct: 403 EAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKF 462
Query: 446 XXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 463 KSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 501
Score = 61.7 bits (143), Expect = 6e-09
Identities = 37/166 (22%), Positives = 75/166 (45%), Gaps = 1/166 (0%)
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QL EE EA+ +LER + N ++ + K ++
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK-RFQKEIENLTQQYE 59
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
A + +EK K+RLQ E++ L++DL+ L+K+ + +++ E K+ +
Sbjct: 60 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 119
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
++ + + R K+T+ ++ L++ E K+ L R NK + ++ D
Sbjct: 120 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMED 165
Score = 56.0 bits (129), Expect = 3e-07
Identities = 84/417 (20%), Positives = 158/417 (37%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 187 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 246
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K K QA++
Sbjct: 247 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMK 305
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 306 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 365
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 366 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 422
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 423 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 463
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 464 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 521
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 522 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 578
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 383 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 442
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 443 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 502
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 503 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 556
Score = 40.7 bits (91), Expect = 0.012
Identities = 42/251 (16%), Positives = 99/251 (39%), Gaps = 5/251 (1%)
Query: 190 ELNRTIVDITSHKQRLSQENIELV---KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXX 246
+LN + + ++ +S NI+L K++QD +E + K + +
Sbjct: 1 QLNEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEE 60
Query: 247 XXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXX 306
+ ++++ +L+ + V L+ + + +LE++ K + + ++
Sbjct: 61 KAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADE 120
Query: 307 XXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE 366
K + L AK +E+ L++E+E L+ + E
Sbjct: 121 RDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKDDVGKNVHE 179
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARE 426
L+K LE E+K++LEE + T+ + +Q + + ++ + +D E
Sbjct: 180 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 427 NKK-MGDDLHD 436
++ + LH+
Sbjct: 240 KRRQLQRQLHE 250
Score = 34.7 bits (76), Expect = 0.79
Identities = 46/312 (14%), Positives = 114/312 (36%), Gaps = 5/312 (1%)
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHI 186
D ++++ T E+ K +FQ E+ L Q E + KT RL+ + +L +
Sbjct: 25 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 84
Query: 187 KIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS-QIASQXXXXXXXXX 245
++ R +V KQR + + K + + + ++ + ++
Sbjct: 85 DLDN-QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 143
Query: 246 XXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXX 305
+ ++ ++E + ++ + +LE+ ++ +++
Sbjct: 144 EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED 203
Query: 306 XXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
L A+ E+++ +LQ ++ +LE
Sbjct: 204 ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRA 263
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD---A 422
++LE +++ + + ++ E+ + +R Q +++ EL+ R +D A
Sbjct: 264 LAAAAKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQRELEDARASRDEIFA 323
Query: 423 LARENKKMGDDL 434
A+EN+K L
Sbjct: 324 TAKENEKKAKSL 335
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 464 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 523
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 524 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 557
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/72 (27%), Positives = 37/72 (51%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 486 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 545
Query: 85 QFEINRKRDTEL 96
RK EL
Sbjct: 546 INANRRKLQREL 557
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 63.7 bits (148), Expect = 1e-09
Identities = 76/417 (18%), Positives = 165/417 (39%), Gaps = 15/417 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE+ + L +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 911 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 1030 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNN 1083
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/284 (21%), Positives = 114/284 (40%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 894
Score = 48.0 bits (109), Expect = 8e-05
Identities = 84/413 (20%), Positives = 166/413 (40%), Gaps = 46/413 (11%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E L R + +E AR LE +L A G + + S
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEAAQGNLSQ---------------TTQEQKQLSEK 921
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL---IIDLEKANGTAR-ELQKRTEQLERV 377
L N +E ++ L +E L + D+ +A+ T+ ELQ + ++ +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 981
Query: 378 N----IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALAR 425
N E++ +L+E E+++ Q E++ + EL D R Q +AL +
Sbjct: 982 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 1034
Score = 46.0 bits (104), Expect = 3e-04
Identities = 38/179 (21%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQL-SERLEEAEGGAESQFE-INR 90
+ ++EDK+ ++ +LE ER + + Q+ QL +E L+E + + + I+
Sbjct: 1063 VKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISL 1122
Query: 91 KRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+R + LK R + LE + S+E L + + + + +++++ + +A + +
Sbjct: 1123 ERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSNRRL 1179
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L +E
Sbjct: 1180 ERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 1235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 888 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 947
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 948 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 1000
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 1001 E---KSRLTAMKMQDEMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E +R +L +E AR
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 1114 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 1173
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 1174 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 1226
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 1227 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 1038 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 1098 MEQLRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 1148
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 1149 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 1205
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 1206 LRLKAMKRQVEEAEEEIDRLESSKKKL 1232
Score = 38.7 bits (86), Expect = 0.048
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 925
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 926 S-EQKEQLRRLKNEMEN 941
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 1196
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 1197 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255
Query: 167 KITISK 172
+ + K
Sbjct: 1256 DLRLKK 1261
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 63.7 bits (148), Expect = 1e-09
Identities = 76/417 (18%), Positives = 165/417 (39%), Gaps = 15/417 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE+ + L +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 911 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 1030 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNN 1083
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/284 (21%), Positives = 114/284 (40%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 894
Score = 48.0 bits (109), Expect = 8e-05
Identities = 84/413 (20%), Positives = 166/413 (40%), Gaps = 46/413 (11%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E L R + +E AR LE +L A G + + S
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEAAQGNLSQ---------------TTQEQKQLSEK 921
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL---IIDLEKANGTAR-ELQKRTEQLERV 377
L N +E ++ L +E L + D+ +A+ T+ ELQ + ++ +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 981
Query: 378 N----IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALAR 425
N E++ +L+E E+++ Q E++ + EL D R Q +AL +
Sbjct: 982 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 1034
Score = 46.0 bits (104), Expect = 3e-04
Identities = 38/179 (21%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQL-SERLEEAEGGAESQFE-INR 90
+ ++EDK+ ++ +LE ER + + Q+ QL +E L+E + + + I+
Sbjct: 1063 VKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISL 1122
Query: 91 KRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+R + LK R + LE + S+E L + + + + +++++ + +A + +
Sbjct: 1123 ERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSNRRL 1179
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L +E
Sbjct: 1180 ERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 1235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 888 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 947
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 948 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 1000
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 1001 E---KSRLTAMKMQDEMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E +R +L +E AR
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 1114 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 1173
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 1174 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 1226
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 1227 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 1038 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 1098 MEQLRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 1148
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 1149 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 1205
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 1206 LRLKAMKRQVEEAEEEIDRLESSKKKL 1232
Score = 38.7 bits (86), Expect = 0.048
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 925
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 926 S-EQKEQLRRLKNEMEN 941
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 1196
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 1197 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255
Query: 167 KITISK 172
+ + K
Sbjct: 1256 DLRLKK 1261
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 63.7 bits (148), Expect = 1e-09
Identities = 76/417 (18%), Positives = 165/417 (39%), Gaps = 15/417 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE+ + L +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 911 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 1030 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNN 1083
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/284 (21%), Positives = 114/284 (40%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 894
Score = 48.0 bits (109), Expect = 8e-05
Identities = 84/413 (20%), Positives = 166/413 (40%), Gaps = 46/413 (11%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E L R + +E AR LE +L A G + + S
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEAAQGNLSQ---------------TTQEQKQLSEK 921
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL---IIDLEKANGTAR-ELQKRTEQLERV 377
L N +E ++ L +E L + D+ +A+ T+ ELQ + ++ +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 981
Query: 378 N----IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALAR 425
N E++ +L+E E+++ Q E++ + EL D R Q +AL +
Sbjct: 982 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 1034
Score = 46.0 bits (104), Expect = 3e-04
Identities = 38/179 (21%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQL-SERLEEAEGGAESQFE-INR 90
+ ++EDK+ ++ +LE ER + + Q+ QL +E L+E + + + I+
Sbjct: 1063 VKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISL 1122
Query: 91 KRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+R + LK R + LE + S+E L + + + + +++++ + +A + +
Sbjct: 1123 ERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSNRRL 1179
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L +E
Sbjct: 1180 ERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 1235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 888 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 947
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 948 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 1000
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 1001 E---KSRLTAMKMQDEMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E +R +L +E AR
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 1114 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 1173
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 1174 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 1226
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 1227 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 1038 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 1098 MEQLRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 1148
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 1149 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 1205
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 1206 LRLKAMKRQVEEAEEEIDRLESSKKKL 1232
Score = 38.7 bits (86), Expect = 0.048
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 925
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 926 S-EQKEQLRRLKNEMEN 941
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 1196
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 1197 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255
Query: 167 KITISK 172
+ + K
Sbjct: 1256 DLRLKK 1261
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 63.7 bits (148), Expect = 1e-09
Identities = 76/417 (18%), Positives = 165/417 (39%), Gaps = 15/417 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE+ + L +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 910
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 911 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 1029
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 1030 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNN 1083
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/284 (21%), Positives = 114/284 (40%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 894
Score = 48.0 bits (109), Expect = 8e-05
Identities = 84/413 (20%), Positives = 166/413 (40%), Gaps = 46/413 (11%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E L R + +E AR LE +L A G + + S
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEAAQGNLSQ---------------TTQEQKQLSEK 921
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL---IIDLEKANGTAR-ELQKRTEQLERV 377
L N +E ++ L +E L + D+ +A+ T+ ELQ + ++ +
Sbjct: 922 LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 981
Query: 378 N----IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALAR 425
N E++ +L+E E+++ Q E++ + EL D R Q +AL +
Sbjct: 982 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 1034
Score = 46.0 bits (104), Expect = 3e-04
Identities = 38/179 (21%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQL-SERLEEAEGGAESQFE-INR 90
+ ++EDK+ ++ +LE ER + + Q+ QL +E L+E + + + I+
Sbjct: 1063 VKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISL 1122
Query: 91 KRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+R + LK R + LE + S+E L + + + + +++++ + +A + +
Sbjct: 1123 ERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSNRRL 1179
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L +E
Sbjct: 1180 ERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 1235
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 888 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 947
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 948 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 1000
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 1001 E---KSRLTAMKMQDEMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E +R +L +E AR
Sbjct: 1054 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQ 1113
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 1114 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 1173
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 1174 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 1226
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 1227 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 1038 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 1098 MEQLRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 1148
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 1149 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 1205
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 1206 LRLKAMKRQVEEAEEEIDRLESSKKKL 1232
Score = 38.7 bits (86), Expect = 0.048
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 925
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 926 S-EQKEQLRRLKNEMEN 941
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 1196
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 1197 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255
Query: 167 KITISK 172
+ + K
Sbjct: 1256 DLRLKK 1261
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 63.7 bits (148), Expect = 1e-09
Identities = 76/417 (18%), Positives = 165/417 (39%), Gaps = 15/417 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 416 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 475
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 476 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 535
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 536 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 595
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE+ + L +
Sbjct: 596 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQ 655
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 656 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 714
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 715 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQD 774
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 775 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNN 828
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/284 (21%), Positives = 114/284 (40%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 359 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 415
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 416 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 475
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 476 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 535
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 536 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 595
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 596 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 639
Score = 48.0 bits (109), Expect = 8e-05
Identities = 84/413 (20%), Positives = 166/413 (40%), Gaps = 46/413 (11%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 382 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 441
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 442 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 501
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 502 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 561
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 562 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 621
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
E L R + +E AR LE +L A G + + S
Sbjct: 622 EEALVHARKEEKEAVSARRALENELEAAQGNLSQ---------------TTQEQKQLSEK 666
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL---IIDLEKANGTAR-ELQKRTEQLERV 377
L N +E ++ L +E L + D+ +A+ T+ ELQ + ++ +
Sbjct: 667 LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK 726
Query: 378 N----IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALAR 425
N E++ +L+E E+++ Q E++ + EL D R Q +AL +
Sbjct: 727 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTK 779
Score = 46.8 bits (106), Expect = 2e-04
Identities = 70/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 633 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 692
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 693 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 745
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 746 E---KSRLTAMKMQDEMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 798
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E VR +L +E AR
Sbjct: 799 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQVRNELLQERAARQ 858
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 859 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 918
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 919 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 971
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 972 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1002
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/182 (22%), Positives = 95/182 (52%), Gaps = 15/182 (8%)
Query: 33 LSRLEDKIRLIQDDLESERE----LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE- 87
+ ++EDK+ ++ +LE ER L +RI R + + QV +E L+E + + +
Sbjct: 808 VKQMEDKVSQLEMELEEERNNSDLLSERISRSREQME-QV--RNELLQERAARQDLECDK 864
Query: 88 INRKRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
I+ +R + LK R + LE + S+E L + + + + +++++ + +A +
Sbjct: 865 ISLERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSN 921
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L
Sbjct: 922 RRLERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQ 978
Query: 207 QE 208
+E
Sbjct: 979 RE 980
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 783 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQ 842
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 843 MEQVRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 893
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 894 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 950
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 951 LRLKAMKRQVEEAEEEIDRLESSKKKL 977
Score = 38.7 bits (86), Expect = 0.048
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 498 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 557
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 558 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 613
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 614 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 670
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 671 S-EQKEQLRRLKNEMEN 686
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 882 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 941
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 942 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1000
Query: 167 KITISK 172
+ + K
Sbjct: 1001 DLRLKK 1006
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 352 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 411
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 412 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 463
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2344 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2400
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2401 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2516
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2517 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2633
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2634 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2690
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2691 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2735
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2415 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2474
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2475 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2534
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2535 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2591
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2592 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2651
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2652 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2690
Score = 49.6 bits (113), Expect = 3e-05
Identities = 95/482 (19%), Positives = 170/482 (35%), Gaps = 39/482 (8%)
Query: 24 IEYSADLSALSRLEDKIRL--IQDDLESERELRQ-------RIEREKADLSVQVIQLSER 74
+E L+ R E++ RL ++ LE +R+L + + ERE +L ++ + R
Sbjct: 1481 MEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRIQEEVVR 1540
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
EEA A+ Q R EL +LR+ E A ++ I +E+I
Sbjct: 1541 REEAAVDAQQQ---KRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRI----EEEIRV 1593
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
+ E+++ + E+ L A+ E +K + ERL + + + +
Sbjct: 1594 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1653
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ + ++E ++ +++L++ E Q +
Sbjct: 1654 LASRVKAEAEAAREKQRALQALEELRLQAEEAERWLCQAEVE---------RARQVQVAL 1704
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWR--SKFXXXXXXXXXXXX 312
+ E +L+S R E++ LER L + + + R ++
Sbjct: 1705 ETAQRSAEAELQSKRASFAEKT---AQLERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1761
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE 372
+ L + V +QKS Q+E E E+A AR K E
Sbjct: 1762 EEAERQLERWQLKANEALRLRLQAEEVLQQKSLAQAEAEK---QKEEAEREARRRGKAEE 1818
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
Q R + LE+ QL E T + + EL R+ E ++ +Q+ L E ++
Sbjct: 1819 QAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL-- 1876
Query: 433 DLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
R + K E R E+ QRL AE G+
Sbjct: 1877 ----QREAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGR 1932
Query: 493 FR 494
FR
Sbjct: 1933 FR 1934
Score = 49.6 bits (113), Expect = 3e-05
Identities = 76/416 (18%), Positives = 159/416 (38%), Gaps = 32/416 (7%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSE----RLEEAEGGAESQFEINRKRDTEL 96
RL +D+ R L ++ + KAD+ ++ QL + LE +G E R+ + E+
Sbjct: 2005 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 2064
Query: 97 LKLRKLLEDVHLESEETAHLLKK--KNQEIVIDFQEQ--IDQLTKTKARAEKEKSKFQAE 152
L L+ E E L + N E + +EQ ++ + + AE+E+ + +AE
Sbjct: 2065 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2124
Query: 153 --VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSH--KQRL 205
V + LA E +++ + ERL+ + E L + E+ + + + ++RL
Sbjct: 2125 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRL 2184
Query: 206 SQENIELVKEVQDLKVNIENVVY--------LKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
E VQ + ++ + L+ + + S
Sbjct: 2185 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQS 2244
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHW---RSKFXXXXXXXXXXXXXX 314
QVE + E ++ EE+++AR + K E R++
Sbjct: 2245 RRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2303
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
K+ + ++ + Q + +L +L++ A E ++ Q+
Sbjct: 2304 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2363
Query: 375 ERVNIEIKSRLEETVQLYEQTQRD-----LRNKQTELQRVSHELDKTREQKDALAR 425
E ++ ++EE +L + + + LR+K + + E +K ++ + AR
Sbjct: 2364 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 2419
Score = 48.4 bits (110), Expect = 6e-05
Identities = 70/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1286 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1345
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1346 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1397
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1398 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1457
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1458 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1517
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + I + + +
Sbjct: 1518 QAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1577
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1578 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1637
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1638 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1672
Score = 45.2 bits (102), Expect = 6e-04
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1826 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1885
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1886 KRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1945
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1946 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 2005
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 2006 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 2052
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 2053 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 2110
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 2111 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARSLRERAEQES 2169
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2170 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDRLRGEAEAARRAAE 2228
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2229 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2288
Query: 488 AEFGQFR 494
AE R
Sbjct: 2289 AEQAALR 2295
Score = 44.0 bits (99), Expect = 0.001
Identities = 80/421 (19%), Positives = 166/421 (39%), Gaps = 34/421 (8%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT--E 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2146 EEVERLKAKVEEARSLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2204
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + + +
Sbjct: 2205 TLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA-Q 2263
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2264 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2321
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+E+ L++ +E + K+ + + QVE +L SVRVQ+
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRS-------QVEEELFSVRVQM 2374
Query: 273 EEES--EARLDLERQLVKANGEIGHWR--------SKFXXXXXXXXXXXXXXXXKYSXXX 322
EE S +AR++ E + + + R K +
Sbjct: 2375 EELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2434
Query: 323 XXXXXXXXTLIAKINNVEKQ----KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
L K+ + Q +RL++E E+L E A AR LQ+ EQ+ +
Sbjct: 2435 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2494
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDL 434
E + T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ L
Sbjct: 2495 AEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKL 2554
Query: 435 H 435
H
Sbjct: 2555 H 2555
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2658 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2717
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2718 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2761
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2234 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2290
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2291 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2406
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2407 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2523
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2581 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2305 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2364
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2365 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2424
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2425 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2481
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2482 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2541
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1345 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1401
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1402 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1461
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1462 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1521
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1522 EAERLRRQVQDESQRKRQAEVELASRV---KAETEAAREKQRALQALEELRLQAEEAERR 1578
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1579 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1638
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1639 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1695
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1696 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1755
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1756 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1809
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1810 EKSKQRLEAEAGRFR 1824
Score = 46.4 bits (105), Expect = 2e-04
Identities = 68/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + ++V + ER+ + ++ R EL +L +
Sbjct: 1176 LRDELRGAQEVGERLQQRHGERDLEVERWRERVAQVLERWQAVLAQTDLRQRELEQLGRQ 1235
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1236 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1287
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1288 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1347
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1348 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1407
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1408 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1467
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1468 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1527
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1528 RQVQDESQRKRQAEVELASRVKAETEAAREKQRAL 1562
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/414 (16%), Positives = 163/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ ++E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2036 EEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2094
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE-EQAQ 2153
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2154 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2211
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2272 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2331
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2332 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2391
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2392 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Score = 44.8 bits (101), Expect = 7e-04
Identities = 104/487 (21%), Positives = 183/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1716 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1775
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1776 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1835
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1836 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1895
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1896 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1942
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1943 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 2000
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L ++E+A R Q+
Sbjct: 2001 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKANVEEARRLRERAEQES 2059
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2060 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2118
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2119 EAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2178
Query: 488 AEFGQFR 494
AE R
Sbjct: 2179 AEQAALR 2185
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/415 (17%), Positives = 158/415 (38%), Gaps = 34/415 (8%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A + +RL+ + + + E+E E R+ R D + Q +L E+ + + E
Sbjct: 1864 EKLAAIGEATRLKTEAEIALKEKEAENE---RLRRLAEDEAFQRRRLEEQAAQHKADIEE 1920
Query: 85 QF-EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+ ++ + D+EL + + L+ED L+++ Q +E+I L + +A
Sbjct: 1921 RLAQLRKASDSELERQKGLVEDT----------LRQRRQ-----VEEEILALKASFEKAA 1965
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K++ + E+ + + E+ + K R +E + E + + ++
Sbjct: 1966 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEE 2025
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+++ ++EV+ LK N+E L+ + + H +
Sbjct: 2026 EAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2085
Query: 264 DLESVRVQLEEESEARLDLERQLV-KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
Q E+E + L E+ ++ + GE ++ + +
Sbjct: 2086 Q------QKEQELQQTLQQEQSVLDQLRGE-----AEAARRAAEEAEEARVQAEREAAQA 2134
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L K + E+ ++R Q++ + E AR Q L R
Sbjct: 2135 RRQVEEAERL--KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAAL-RQKQAAD 2191
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+ +E+ + EQT R + EL + +L++T QK+ L E +++ + +A
Sbjct: 2192 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2246
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2607
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2608 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2651
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2234 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2290
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2291 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2406
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2407 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2523
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2581 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2305 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2364
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2365 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2424
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2425 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2481
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2482 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2541
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1345 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1401
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1402 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1461
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1462 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1521
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1522 EAERLRRQVQDESQRKRQAEVELASRV---KAETEAAREKQRALQALEELRLQAEEAERR 1578
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1579 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1638
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1639 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1695
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1696 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1755
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1756 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1809
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1810 EKSKQRLEAEAGRFR 1824
Score = 46.4 bits (105), Expect = 2e-04
Identities = 68/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + ++V + ER+ + ++ R EL +L +
Sbjct: 1176 LRDELRGAQEVGERLQQRHGERDLEVERWRERVAQVLERWQAVLAQTDLRQRELEQLGRQ 1235
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1236 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1287
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1288 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1347
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1348 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1407
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1408 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1467
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1468 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1527
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1528 RQVQDESQRKRQAEVELASRVKAETEAAREKQRAL 1562
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/414 (16%), Positives = 163/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ ++E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2036 EEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2094
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAE-EQAQ 2153
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2154 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2211
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2272 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2331
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2332 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2391
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2392 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Score = 44.8 bits (101), Expect = 7e-04
Identities = 104/487 (21%), Positives = 183/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1716 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1775
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1776 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1835
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1836 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1895
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1896 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1942
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1943 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 2000
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L ++E+A R Q+
Sbjct: 2001 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKANVEEARRLRERAEQES 2059
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2060 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2118
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2119 EAEEARVQAEREAAQARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2178
Query: 488 AEFGQFR 494
AE R
Sbjct: 2179 AEQAALR 2185
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/415 (17%), Positives = 158/415 (38%), Gaps = 34/415 (8%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A + +RL+ + + + E+E E R+ R D + Q +L E+ + + E
Sbjct: 1864 EKLAAIGEATRLKTEAEIALKEKEAENE---RLRRLAEDEAFQRRRLEEQAAQHKADIEE 1920
Query: 85 QF-EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+ ++ + D+EL + + L+ED L+++ Q +E+I L + +A
Sbjct: 1921 RLAQLRKASDSELERQKGLVEDT----------LRQRRQ-----VEEEILALKASFEKAA 1965
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K++ + E+ + + E+ + K R +E + E + + ++
Sbjct: 1966 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEE 2025
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+++ ++EV+ LK N+E L+ + + H +
Sbjct: 2026 EAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2085
Query: 264 DLESVRVQLEEESEARLDLERQLV-KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
Q E+E + L E+ ++ + GE ++ + +
Sbjct: 2086 Q------QKEQELQQTLQQEQSVLDQLRGE-----AEAARRAAEEAEEARVQAEREAAQA 2134
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L K + E+ ++R Q++ + E AR Q L R
Sbjct: 2135 RRQVEEAERL--KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAAL-RQKQAAD 2191
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+ +E+ + EQT R + EL + +L++T QK+ L E +++ + +A
Sbjct: 2192 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 2246
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2607
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2608 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2651
>DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein
kinase beta (DMPK-like) protein.
Length = 1711
Score = 62.5 bits (145), Expect = 3e-09
Identities = 48/197 (24%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 28 ADLSALSR-LEDKIRLIQDDLESERELR------QRIEREKADLSVQVIQLSERLEEAEG 80
AD + L R LED + L Q+ +S + LR + + +EK +L Q+++ SERL+
Sbjct: 502 ADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAK 561
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + + E +L + + ++ + ++ + L+ K +E+ + Q ++D + +
Sbjct: 562 ELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQ-KVDAMRQEMR 620
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELH-IKIEELNRTIVDIT 199
RAEK + + +A++ + +A+ K + C+++E SEL +K+++ R
Sbjct: 621 RAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME---SELEALKVKQGGRGAGATL 677
Query: 200 SHKQRLSQENIELVKEV 216
H+Q +S+ EL K+V
Sbjct: 678 EHQQEISKIKSELEKKV 694
Score = 48.0 bits (109), Expect = 8e-05
Identities = 54/272 (19%), Positives = 124/272 (45%), Gaps = 12/272 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQ--RIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
+ L++ ED R ++ L+ E R+ R+E+EK +LS ++ + ++ ++ G S+
Sbjct: 422 NTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG--SSRALS 479
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI-----DFQEQIDQLTKTKARAE 143
N RD E+ KL + +E + + ++ L ++ + + D +++ L K
Sbjct: 480 NSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVR 539
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+EK + ++ E ++++ KE + + SEL+ ++ EL R S +
Sbjct: 540 QEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAEL-RAQKQKVSRQL 598
Query: 204 RLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
R +E +E+ ++V ++ + L+ ++ +Q Q+E
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME 658
Query: 263 IDLESVRV-QLEEESEARLDLERQLVKANGEI 293
+LE+++V Q + A L+ ++++ K E+
Sbjct: 659 SELEALKVKQGGRGAGATLEHQQEISKIKSEL 690
Score = 39.1 bits (87), Expect = 0.037
Identities = 43/192 (22%), Positives = 91/192 (47%), Gaps = 14/192 (7%)
Query: 46 DLESERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
+ ER+LR+ E ++ + ++ +++ + A E Q EI++ + +EL K + L
Sbjct: 639 EASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIK-SELEK-KVLF 696
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
+ L E +H+L+ KN ++++ + +KE + ++ + + N
Sbjct: 697 YEEELVRREASHVLEVKN------VKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNE 750
Query: 164 TKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+E + TI ER + + + K+ N + S +L+ +N +L E+QDL
Sbjct: 751 MEEAVGTIKDKYERERAMLFDENKKLTAENEKLC---SFVDKLTAQNRQLEDELQDLAAK 807
Query: 223 IENVVYLKSQIA 234
E+V + ++QIA
Sbjct: 808 KESVAHWEAQIA 819
>BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein.
Length = 933
Score = 62.5 bits (145), Expect = 3e-09
Identities = 48/197 (24%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 28 ADLSALSR-LEDKIRLIQDDLESERELR------QRIEREKADLSVQVIQLSERLEEAEG 80
AD + L R LED + L Q+ +S + LR + + +EK +L Q+++ SERL+
Sbjct: 502 ADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAK 561
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + + E +L + + ++ + ++ + L+ K +E+ + Q ++D + +
Sbjct: 562 ELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQ-KVDAMRQEMR 620
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELH-IKIEELNRTIVDIT 199
RAEK + + +A++ + +A+ K + C+++E SEL +K+++ R
Sbjct: 621 RAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME---SELEALKVKQGGRGAGATL 677
Query: 200 SHKQRLSQENIELVKEV 216
H+Q +S+ EL K+V
Sbjct: 678 EHQQEISKIKSELEKKV 694
Score = 48.0 bits (109), Expect = 8e-05
Identities = 54/272 (19%), Positives = 124/272 (45%), Gaps = 12/272 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQ--RIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
+ L++ ED R ++ L+ E R+ R+E+EK +LS ++ + ++ ++ G S+
Sbjct: 422 NTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG--SSRALS 479
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI-----DFQEQIDQLTKTKARAE 143
N RD E+ KL + +E + + ++ L ++ + + D +++ L K
Sbjct: 480 NSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVR 539
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+EK + ++ E ++++ KE + + SEL+ ++ EL R S +
Sbjct: 540 QEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAEL-RAQKQKVSRQL 598
Query: 204 RLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
R +E +E+ ++V ++ + L+ ++ +Q Q+E
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME 658
Query: 263 IDLESVRV-QLEEESEARLDLERQLVKANGEI 293
+LE+++V Q + A L+ ++++ K E+
Sbjct: 659 SELEALKVKQGGRGAGATLEHQQEISKIKSEL 690
Score = 39.1 bits (87), Expect = 0.037
Identities = 43/192 (22%), Positives = 91/192 (47%), Gaps = 14/192 (7%)
Query: 46 DLESERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
+ ER+LR+ E ++ + ++ +++ + A E Q EI++ + +EL K + L
Sbjct: 639 EASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIK-SELEK-KVLF 696
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
+ L E +H+L+ KN ++++ + +KE + ++ + + N
Sbjct: 697 YEEELVRREASHVLEVKN------VKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNE 750
Query: 164 TKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+E + TI ER + + + K+ N + S +L+ +N +L E+QDL
Sbjct: 751 MEEAVGTIKDKYERERAMLFDENKKLTAENEKLC---SFVDKLTAQNRQLEDELQDLAAK 807
Query: 223 IENVVYLKSQIA 234
E+V + ++QIA
Sbjct: 808 KESVAHWEAQIA 819
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2207 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2263
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2264 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2379
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2496
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2497 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2553
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2554 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2598
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2278 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2337
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2338 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2397
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2398 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2454
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2455 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2514
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2553
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1318 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1374
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1375 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1551
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1552 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1611
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1668
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1729 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1782
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1783 EKSKQRLEAEAGRFR 1797
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1149 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1208
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1209 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1260
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1261 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1320
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1321 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1380
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2009 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2067
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2126
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2127 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2245 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2304
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2305 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2364
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2365 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2418
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1869 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1915
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1973
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2032
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2091
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 488 AEFGQFR 494
AE R
Sbjct: 2152 AEQAALR 2158
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1931 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2225
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2226 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2281
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2282 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2341
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2342 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2401
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2402 DAQRFRKQAEEIGEKLH 2418
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2211 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2267
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2268 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2326
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2383
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2384 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2500
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2501 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2557
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2558 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2602
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2282 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2341
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2342 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2401
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2402 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2458
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2459 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2518
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2519 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2557
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1322 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1378
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1379 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1438
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1439 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1498
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1499 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1555
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1556 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1615
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1616 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1672
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1673 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1732
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1733 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1786
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1787 EKSKQRLEAEAGRFR 1801
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1153 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1212
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1213 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1264
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1265 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1324
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1325 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1384
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1385 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1444
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1504
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1505 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1539
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2013 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2071
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2072 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2130
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2131 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2188
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2189 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2248
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2249 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2308
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2309 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2368
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2369 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2422
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1693 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1752
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1753 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1812
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1813 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1872
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1873 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1919
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1920 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1977
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1978 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2036
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2037 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2095
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2096 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2155
Query: 488 AEFGQFR 494
AE R
Sbjct: 2156 AEQAALR 2162
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1935 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1991
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1992 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2051
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2052 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2111
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2112 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2171
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2172 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2229
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2230 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2285
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2286 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2345
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2346 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2405
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2406 DAQRFRKQAEEIGEKLH 2422
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2525 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2584
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2585 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2628
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2207 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2263
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2264 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2322
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2379
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2380 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2496
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2497 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2553
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2554 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2598
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2278 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2337
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2338 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2397
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2398 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2454
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2455 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2514
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2515 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2553
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1318 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1374
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1375 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1434
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1435 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1551
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1552 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1611
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1612 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1668
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1669 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1728
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1729 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1782
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1783 EKSKQRLEAEAGRFR 1797
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1149 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1208
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1209 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1260
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1261 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1320
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1321 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1380
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1500
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1501 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2009 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2067
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2068 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2126
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2127 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2184
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2185 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2244
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2245 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2304
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2305 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2364
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2365 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2418
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1869 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1915
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1973
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2032
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2091
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2092 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2151
Query: 488 AEFGQFR 494
AE R
Sbjct: 2152 AEQAALR 2158
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1931 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1987
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1988 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2047
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2048 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2107
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2108 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2168 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2225
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2226 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2281
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2282 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2341
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2342 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2401
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2402 DAQRFRKQAEEIGEKLH 2418
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2581 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2624
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2175 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2231
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2232 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2290
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2347
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2348 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2464
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2465 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2521
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2522 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2566
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2246 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2305
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2306 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2365
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2366 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2422
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2423 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2482
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2483 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2521
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1286 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1342
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1343 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1402
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1403 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1462
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1463 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1519
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1520 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1579
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1580 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1636
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1637 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1696
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1697 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1750
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1751 EKSKQRLEAEAGRFR 1765
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1117 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1176
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1177 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1228
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1229 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1288
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1289 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1348
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1349 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1408
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1409 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1468
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1469 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1503
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 1977 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2035
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2036 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2094
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2095 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2152
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2153 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2212
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2213 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2272
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2273 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2332
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2333 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2386
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1657 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1716
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1717 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1776
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1777 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1836
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1837 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1883
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1884 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1941
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1942 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2000
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2001 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2059
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2060 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2119
Query: 488 AEFGQFR 494
AE R
Sbjct: 2120 AEQAALR 2126
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1899 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1955
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1956 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2015
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2016 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2075
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2076 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2135
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2136 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2193
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2194 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2249
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2250 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2309
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2310 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2369
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2370 DAQRFRKQAEEIGEKLH 2386
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2489 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2548
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2549 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2592
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2344 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2400
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2401 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2459
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2516
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2517 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2633
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2634 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2690
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2691 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2735
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2415 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2474
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2475 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2534
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2535 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2591
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2592 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2651
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2652 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2690
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1455 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1511
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1512 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1571
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1572 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1631
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1632 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1688
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1689 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1748
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1749 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1805
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1806 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1865
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1866 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1919
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1920 EKSKQRLEAEAGRFR 1934
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1286 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1345
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1346 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1397
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1398 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1457
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1458 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1517
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1518 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1577
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1578 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1637
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1638 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1672
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2146 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2204
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2205 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2263
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2264 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2321
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2322 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2381
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2382 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2441
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2442 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2501
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2502 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2555
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1826 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1885
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1886 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1945
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1946 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 2005
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 2006 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 2052
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 2053 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 2110
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 2111 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2169
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2170 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2228
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2229 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2288
Query: 488 AEFGQFR 494
AE R
Sbjct: 2289 AEQAALR 2295
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 2068 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2124
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 2125 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2184
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2185 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2244
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2245 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2304
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2305 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2362
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2363 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2418
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2419 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2478
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2479 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2538
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2539 DAQRFRKQAEEIGEKLH 2555
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2658 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2717
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2718 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2761
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2185 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2241
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2242 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2300
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2357
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2358 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2418 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2474
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2475 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2531
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2532 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2576
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2256 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2315
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2316 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2375
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2376 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2432
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2433 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2492
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2493 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2531
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1296 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1352
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1353 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1412
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1413 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1472
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1473 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1529
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1530 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1589
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1590 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1646
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1647 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1706
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1707 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1760
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1761 EKSKQRLEAEAGRFR 1775
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1127 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1186
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1187 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1238
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1239 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1298
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1299 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1358
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1359 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1418
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1419 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1478
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1479 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1513
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 1987 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2045
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2046 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2104
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2105 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2162
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2163 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2222
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2223 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2282
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2283 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2342
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2343 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2396
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1667 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1726
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1727 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1786
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1787 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1846
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1847 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1893
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1894 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1951
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1952 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2010
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2011 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2069
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2070 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2129
Query: 488 AEFGQFR 494
AE R
Sbjct: 2130 AEQAALR 2136
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1909 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1965
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1966 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2025
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2026 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2085
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2086 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2145
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2146 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2203
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2204 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2259
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2260 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2319
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2320 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2379
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2380 DAQRFRKQAEEIGEKLH 2396
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2499 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2558
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2559 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2602
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2193 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2249
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2250 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2308
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2365
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2366 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2426 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2482
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2483 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2539
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2540 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2584
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2264 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2323
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2324 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2383
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2384 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2440
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2441 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2500
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2501 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2539
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1304 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1360
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1361 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1420
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1421 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1480
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1481 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1537
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1538 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1597
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1598 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1654
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1655 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1714
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1715 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1768
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1769 EKSKQRLEAEAGRFR 1783
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1135 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1194
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1195 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1246
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1247 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1306
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1307 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1366
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1367 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1426
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1427 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1486
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1487 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1521
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 1995 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2053
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2054 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2112
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2113 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2170
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2171 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2230
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2231 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2290
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2291 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2350
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2351 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2404
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1675 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1734
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1735 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1794
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1795 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1854
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1855 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1901
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1902 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 1959
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 1960 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2018
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2019 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2077
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2078 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2137
Query: 488 AEFGQFR 494
AE R
Sbjct: 2138 AEQAALR 2144
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1917 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 1973
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 1974 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2033
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2034 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2093
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2094 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2153
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2154 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2211
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2212 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2267
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2268 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2327
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2328 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2387
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2388 DAQRFRKQAEEIGEKLH 2404
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2507 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2566
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2567 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2610
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 62.5 bits (145), Expect = 3e-09
Identities = 88/408 (21%), Positives = 171/408 (41%), Gaps = 26/408 (6%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
E+ RL + E+ R+ R ++E E + VQ+ +LS+ E AE++ I R +D
Sbjct: 2234 EELQRLKAEATEAARQ-RSQVEEELFSVRVQMEELSKLKARIE--AENRALILRDKDNTQ 2290
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE-KSKFQA--EV 153
L++ E + +EE A L QE Q + L + +A AEK K K QA E
Sbjct: 2291 RFLQEEAEKMKQVAEEAARL-SVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEA 2349
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
L A+ E + ++K + RL+ ++ ++ E + T +R Q +E+
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF-QRTLEAER--QRQLEMS 2406
Query: 214 KEVQDLKVNIENVVYLKSQ-------IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
E + LK+ + + +++ Q + +EI +
Sbjct: 2407 AEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
E EA +LER+ K E + K +
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLK---SEEMQTVQQEQLLQETQALQQSFL 2523
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+L+ + +E++K++L+ ++ ++ KA E Q++ +Q+E+ + + +E
Sbjct: 2524 SEKDSLLQRERFIEQEKAKLE---QLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + + + +R KQ ELQ++ + R+Q++ LA EN+++ + L
Sbjct: 2581 EARRRQHEAEEGVRRKQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 56.4 bits (130), Expect = 2e-07
Identities = 60/279 (21%), Positives = 126/279 (45%), Gaps = 14/279 (5%)
Query: 25 EYSADLSALSRLEDKIR-LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E +A LS ++ ++R L ++DL +R L +++ +EK + +L E + E
Sbjct: 2305 EEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKE 2364
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE---QIDQLTKTKA 140
E R+ + ++ + L + + T +++ E+ + + ++ ++++ +A
Sbjct: 2365 LAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQA 2424
Query: 141 RAEKEKSKFQA---EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
RAE++ +F+ E+ E L + E T+EK+T+ +T LEI + E L I +
Sbjct: 2425 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQT---LEIQRQQSDHDAERLREAIAE 2481
Query: 198 ITSHKQRLSQENIELVKEVQDLK-VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ K++L QE L + ++++ V E ++ + A
Sbjct: 2482 LEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKA 2541
Query: 257 SLHQVEIDLESVRVQLEEE---SEARLDLERQLVKANGE 292
L Q+ D + QL EE + +++ ERQ + A+ E
Sbjct: 2542 KLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME 2580
Score = 55.6 bits (128), Expect = 4e-07
Identities = 97/495 (19%), Positives = 176/495 (35%), Gaps = 36/495 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
D+ YS +L+ L+ I+ I + L E + E+++A+ ++ ++ LE+
Sbjct: 1345 DLRTHYS-ELTTLT--SQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQ 1401
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETA---HLLKKKNQEIVIDFQEQIDQLTK 137
AE+ + + + E +L++ +++ + EE A K+ QE + ++ + +
Sbjct: 1402 LAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQ 1461
Query: 138 TKAR----AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK----IE 189
KAR AE+ + + + E+ + Q+E +++ + L E + E
Sbjct: 1462 AKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQE 1521
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
E R + QR Q +EL V K E + + +
Sbjct: 1522 EAERLRRQVQDESQRKRQAEVELASRV---KAEAEAAREKQRALQALEELRLQAEEAERR 1578
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEE--------SEARLDLERQLVKANGEIGHWRSKFX 301
QV++ LE+ + E E +E LER L + + + R +
Sbjct: 1579 LRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1638
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI--NNVEKQKSRLQSEVEVLIIDLEK 359
L ++ V +QKS Q+E E E+
Sbjct: 1639 RRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEK---QKEE 1695
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
A AR K EQ R + LE+ QL E T + + EL R+ E ++ +Q
Sbjct: 1696 AEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ 1755
Query: 420 KDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAE 479
+ L E ++ R + + E R
Sbjct: 1756 RQLLEEELARL------QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTS 1809
Query: 480 EQRSQRLTAEFGQFR 494
E+ QRL AE G+FR
Sbjct: 1810 EKSKQRLEAEAGRFR 1824
Score = 47.2 bits (107), Expect = 1e-04
Identities = 69/395 (17%), Positives = 149/395 (37%), Gaps = 22/395 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D+L +E+ +R+++ + V+V + ER+ + ++ R EL +L +
Sbjct: 1176 LRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQ 1235
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L ++ L+ + QEQI + ++A +E+ + + LL ++E
Sbjct: 1236 LRYYRESADPLGAWLQDARRR-----QEQIQAMPLADSQAVREQLR---QEQALLEEIER 1287
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITS--HKQRLSQENIELVKEVQDLK 220
++ + ++ I + +++ + + S K ++ + +++E DL+
Sbjct: 1288 HGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLR 1347
Query: 221 VNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
+ + L SQ I+ L +VE LE R E +
Sbjct: 1348 THYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHA 1407
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+A+ ER+ + + + + +
Sbjct: 1408 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1467
Query: 337 NNVEKQKSRLQSEVEVLIIDLE----KANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
E+ + R++ E+ V+ + LE + G ELQ + E + + EE +L
Sbjct: 1468 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLR 1527
Query: 393 EQTQ-RDLRNKQTELQ---RVSHELDKTREQKDAL 423
Q Q R +Q E++ RV E + RE++ AL
Sbjct: 1528 RQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1562
Score = 44.4 bits (100), Expect = 0.001
Identities = 69/414 (16%), Positives = 162/414 (39%), Gaps = 20/414 (4%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD--TE 95
+++ ++ +E R LR+R E+E A + +++ +AE A + F + +K +
Sbjct: 2036 EEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 2094
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L+ + + D E A ++ +E + + + Q + AE+ K + E +
Sbjct: 2095 TLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE-EQAQ 2153
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIEL 212
AQ + EK+ E +E + + ++ HK+ Q + ++
Sbjct: 2154 ARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQV 2211
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE---SVR 269
+E+ L++ +E + K+ + + L V + +E ++
Sbjct: 2212 EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLK 2271
Query: 270 VQLEEESEARL----DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
++E E+ A + D ++ ++ E ++
Sbjct: 2272 ARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQ 2331
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
++ + ++ +RL++E E+L E A AR LQ+ EQ+ + E
Sbjct: 2332 RALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGF 2391
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDK--TREQKDA--LARENKKMGDDLH 435
+ T++ Q Q ++ + L+ E+ + R ++DA ++ +++G+ LH
Sbjct: 2392 QRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLH 2445
Score = 44.0 bits (99), Expect = 0.001
Identities = 104/487 (21%), Positives = 182/487 (37%), Gaps = 51/487 (10%)
Query: 42 LIQDDLESEREL-----RQRI--EREKADLSVQVIQ-------LSERLEEAEGGAESQFE 87
L + +LE +R+L +QR+ E+E L + Q L E L + A + +
Sbjct: 1716 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1775
Query: 88 INRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVID---FQEQIDQLTKTKA 140
++ + EL K+R LL EE+ +K Q + + F+E ++ + +A
Sbjct: 1776 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1835
Query: 141 RAEKEKSKFQ---AEVYELLAQVENVTKEKITISKTCERL----EITISELHIKIEELNR 193
AE+ K + Q + A+ E V EK+ RL EI + E + E L R
Sbjct: 1836 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1895
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXX 253
D ++RL + + K +IE ++A
Sbjct: 1896 LAEDEAFQRRRLEE-------QAAQHKADIE------ERLAQLRKASDSELERQKGLVED 1942
Query: 254 XXASLHQVEIDLESVRVQLEEESEARLDLERQL--VKANGEIGHWRSKFXXXXXXXXXXX 311
QVE ++ +++ E+ + + +LE +L +++N E RSK
Sbjct: 1943 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAE-DTLRSK-EQAELEAARQR 2000
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKR 370
+ +L A+ ++K+ L+ EVE L +E+A R Q+
Sbjct: 2001 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2059
Query: 371 TEQLERVNIEIKSRL--EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
QL+ + RL EE + Q++ +QT LQ+ LD+ R + +A R +
Sbjct: 2060 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQT-LQQEQSVLDQLRGEAEAARRAAE 2118
Query: 429 KMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRK-AEEQRSQRLT 487
+ + A A AE RK AE++ ++R
Sbjct: 2119 EAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQ 2178
Query: 488 AEFGQFR 494
AE R
Sbjct: 2179 AEQAALR 2185
Score = 35.5 bits (78), Expect = 0.45
Identities = 83/497 (16%), Positives = 175/497 (35%), Gaps = 19/497 (3%)
Query: 9 KYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLI-QDDLES--ERELRQRIEREKADLS 65
K ++ + G ++ +E S ED +R Q +LE+ +R+L ER + +
Sbjct: 1958 KASFEKAAAGKAELELELGR---IRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 2014
Query: 66 VQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE-I 124
+V + EEA ++ E + ++ + R+L E ES L ++ Q+ +
Sbjct: 2015 ERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRL 2074
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ + + + + ++ + Q+ + +L + E + + + E ++
Sbjct: 2075 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS 2134
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++EE R Q +Q K ++ + + Q
Sbjct: 2135 RRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2194
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR--LDLERQLVKANG-EIGHWRSKFX 301
QVE +L ++R+QLEE + LD E Q +KA E RS+
Sbjct: 2195 EKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQ-- 2252
Query: 302 XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA- 360
+ S LI + + + + LQ E E + E+A
Sbjct: 2253 --VEEELFSVRVQMEELSKLKARIEAENRALI--LRDKDNTQRFLQEEAEKMKQVAEEAA 2308
Query: 361 --NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ A+E + + E + ++ E+ ++ Q ++ + E + + + + +E
Sbjct: 2309 RLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQE 2368
Query: 419 QKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKA 478
Q L + ++M L + A A+A +
Sbjct: 2369 QARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEE 2428
Query: 479 EEQRSQRLTAEFGQFRH 495
+ QR ++ E G+ H
Sbjct: 2429 DAQRFRKQAEEIGEKLH 2445
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/104 (21%), Positives = 51/104 (49%), Gaps = 1/104 (0%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+D++ Q E ++ +Q++E+E+ L + + R EAE G + E ++ + +
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2607
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTK 139
+ +LL + + E LL+++++ + +E Q+ TK
Sbjct: 2608 RQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATK 2651
>AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein
kinase beta protein.
Length = 1711
Score = 62.5 bits (145), Expect = 3e-09
Identities = 48/197 (24%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 28 ADLSALSR-LEDKIRLIQDDLESERELR------QRIEREKADLSVQVIQLSERLEEAEG 80
AD + L R LED + L Q+ +S + LR + + +EK +L Q+++ SERL+
Sbjct: 502 ADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAK 561
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + + E +L + + ++ + ++ + L+ K +E+ + Q ++D + +
Sbjct: 562 ELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQ-KVDAMRQEMR 620
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELH-IKIEELNRTIVDIT 199
RAEK + + +A++ + +A+ K + C+++E SEL +K+++ R
Sbjct: 621 RAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME---SELEALKVKQGGRGAGATL 677
Query: 200 SHKQRLSQENIELVKEV 216
H+Q +S+ EL K+V
Sbjct: 678 EHQQEISKIKSELEKKV 694
Score = 48.0 bits (109), Expect = 8e-05
Identities = 54/272 (19%), Positives = 124/272 (45%), Gaps = 12/272 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQ--RIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
+ L++ ED R ++ L+ E R+ R+E+EK +LS ++ + ++ ++ G S+
Sbjct: 422 NTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG--SSRALS 479
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI-----DFQEQIDQLTKTKARAE 143
N RD E+ KL + +E + + ++ L ++ + + D +++ L K
Sbjct: 480 NSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVR 539
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+EK + ++ E ++++ KE + + SEL+ ++ EL R S +
Sbjct: 540 QEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAEL-RAQKQKVSRQL 598
Query: 204 RLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
R +E +E+ ++V ++ + L+ ++ +Q Q+E
Sbjct: 599 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME 658
Query: 263 IDLESVRV-QLEEESEARLDLERQLVKANGEI 293
+LE+++V Q + A L+ ++++ K E+
Sbjct: 659 SELEALKVKQGGRGAGATLEHQQEISKIKSEL 690
Score = 39.1 bits (87), Expect = 0.037
Identities = 43/192 (22%), Positives = 91/192 (47%), Gaps = 14/192 (7%)
Query: 46 DLESERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
+ ER+LR+ E ++ + ++ +++ + A E Q EI++ + +EL K + L
Sbjct: 639 EASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIK-SELEK-KVLF 696
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
+ L E +H+L+ KN ++++ + +KE + ++ + + N
Sbjct: 697 YEEELVRREASHVLEVKN------VKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNE 750
Query: 164 TKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+E + TI ER + + + K+ N + S +L+ +N +L E+QDL
Sbjct: 751 MEEAVGTIKDKYERERAMLFDENKKLTAENEKLC---SFVDKLTAQNRQLEDELQDLAAK 807
Query: 223 IENVVYLKSQIA 234
E+V + ++QIA
Sbjct: 808 KESVAHWEAQIA 819
>AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein.
Length = 1760
Score = 62.5 bits (145), Expect = 3e-09
Identities = 48/197 (24%), Positives = 101/197 (51%), Gaps = 12/197 (6%)
Query: 28 ADLSALSR-LEDKIRLIQDDLESERELR------QRIEREKADLSVQVIQLSERLEEAEG 80
AD + L R LED + L Q+ +S + LR + + +EK +L Q+++ SERL+
Sbjct: 551 ADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAK 610
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ + + E +L + + ++ + ++ + L+ K +E+ + Q ++D + +
Sbjct: 611 ELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQ-KVDAMRQEMR 669
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELH-IKIEELNRTIVDIT 199
RAEK + + +A++ + +A+ K + C+++E SEL +K+++ R
Sbjct: 670 RAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME---SELEALKVKQGGRGAGATL 726
Query: 200 SHKQRLSQENIELVKEV 216
H+Q +S+ EL K+V
Sbjct: 727 EHQQEISKIKSELEKKV 743
Score = 48.0 bits (109), Expect = 8e-05
Identities = 54/272 (19%), Positives = 124/272 (45%), Gaps = 12/272 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQ--RIEREKADLSVQVIQLSERLEEAEGGAESQFEI 88
+ L++ ED R ++ L+ E R+ R+E+EK +LS ++ + ++ ++ G S+
Sbjct: 471 NTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHG--SSRALS 528
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI-----DFQEQIDQLTKTKARAE 143
N RD E+ KL + +E + + ++ L ++ + + D +++ L K
Sbjct: 529 NSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVR 588
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+EK + ++ E ++++ KE + + SEL+ ++ EL R S +
Sbjct: 589 QEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAEL-RAQKQKVSRQL 647
Query: 204 RLSQENIEL-VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
R +E +E+ ++V ++ + L+ ++ +Q Q+E
Sbjct: 648 RDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQME 707
Query: 263 IDLESVRV-QLEEESEARLDLERQLVKANGEI 293
+LE+++V Q + A L+ ++++ K E+
Sbjct: 708 SELEALKVKQGGRGAGATLEHQQEISKIKSEL 739
Score = 39.1 bits (87), Expect = 0.037
Identities = 43/192 (22%), Positives = 91/192 (47%), Gaps = 14/192 (7%)
Query: 46 DLESERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
+ ER+LR+ E ++ + ++ +++ + A E Q EI++ + +EL K + L
Sbjct: 688 EASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIK-SELEK-KVLF 745
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
+ L E +H+L+ KN ++++ + +KE + ++ + + N
Sbjct: 746 YEEELVRREASHVLEVKN------VKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNE 799
Query: 164 TKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+E + TI ER + + + K+ N + S +L+ +N +L E+QDL
Sbjct: 800 MEEAVGTIKDKYERERAMLFDENKKLTAENEKLC---SFVDKLTAQNRQLEDELQDLAAK 856
Query: 223 IENVVYLKSQIA 234
E+V + ++QIA
Sbjct: 857 KESVAHWEAQIA 868
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/423 (18%), Positives = 175/423 (41%), Gaps = 26/423 (6%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLE-SERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
N + AD+ L +D + +LE S+R L Q++E ++ Q+ +L + L+ E
Sbjct: 1 NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVE----EMRTQLEELEDELQATED- 55
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
A+ + E+N + + + L+ ++EE LL K+ +E+ + +++ K +A
Sbjct: 56 AKLRLEVNMQ--AMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE----RKQRAL 109
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A K K + ++ +L AQ+E K + + K +L+ + + ++EE + +I +
Sbjct: 110 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 169
Query: 202 KQR-------LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+ L E ++L +E+ + + + ++A +
Sbjct: 170 SKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRL 229
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
A + Q+E +LE + +E ++ Q+ N E+ RS
Sbjct: 230 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 289
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
+ A I+ +E + +L+ ++E K A +L +RTE+
Sbjct: 290 KELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE----QEAKERAAANKLVRRTEKK 345
Query: 375 ERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ EI ++E+ + +Q + + ++++ +L++ E+ +K+ +L
Sbjct: 346 LK---EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 402
Query: 435 HDA 437
DA
Sbjct: 403 DDA 405
Score = 41.9 bits (94), Expect = 0.005
Identities = 30/108 (27%), Positives = 54/108 (50%), Gaps = 3/108 (2%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQLY-E 393
++ +EK K L+ +VE + LE+ + + +LE VN++ +K++ E +Q E
Sbjct: 22 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE-VNMQAMKAQFERDLQTRDE 80
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
Q + R +++ + EL+ R+Q+ KKM DL D A I
Sbjct: 81 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQI 128
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 61.3 bits (142), Expect = 8e-09
Identities = 76/409 (18%), Positives = 173/409 (42%), Gaps = 28/409 (6%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + + +Q+D + + +LR++ E E + L ++ +L + AEG + + ++D
Sbjct: 1065 QLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDA 1124
Query: 95 ----ELLKLRKLLED----VHLESEETAHLLKK------KNQEIVIDFQEQIDQLTKTKA 140
E+ L + ED E LL+K +N ++V+ QE++ ++ +
Sbjct: 1125 ATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVV--QEKVREIVRPDP 1182
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK--IEELNRTIVDI 198
+AE E + + E+ E + ++ + E L ++ +K +E+ + D
Sbjct: 1183 KAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDP 1242
Query: 199 TSHK--QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K QRL +E ++ + ++ + ++E + LK +I +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIE--RCDLE-IYQLKKEIQALKDTKPQVQTKEVVQEILQFQ 1299
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
Q + ++ S+R +L EE + ++DLER+ +I +
Sbjct: 1300 EDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYE 1359
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ ++ ++ ++K ++ L+ ++ +LE+ EL++ +
Sbjct: 1360 EEPGLRAEASAFAESIDVELRQIDKLRAELR-RLQRRRTELERQ---LEELERERQARRE 1415
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
E++ RL++ + EQ + + R K T Q+V + D + ++ AL R
Sbjct: 1416 AEREVQ-RLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1463
Score = 48.8 bits (111), Expect = 5e-05
Identities = 42/203 (20%), Positives = 90/203 (44%), Gaps = 8/203 (3%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+L L R ++ ++LE ER+ R+ ERE L ++ L + EA +
Sbjct: 1387 AELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQK 1446
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHL-----LKKKNQEIVIDFQEQIDQLTKTKARA 142
+ ++D + + LL + LE E+ L+ +++ + ++ +
Sbjct: 1447 VVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1505
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI--VDITS 200
+ EK + E+ L + +E ++ K + RLE +SEL + ++ + + +
Sbjct: 1506 QVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREEN 1565
Query: 201 HKQRLSQENIELVKEVQDLKVNI 223
HK +L +EN++L ++N+
Sbjct: 1566 HKLQLERENLQLETRRLQSEINM 1588
Score = 41.1 bits (92), Expect = 0.009
Identities = 84/402 (20%), Positives = 157/402 (39%), Gaps = 34/402 (8%)
Query: 46 DLESERELRQRIEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
D E E+EL QR+ E D + + +++ + +E + +++ ++ K + ++ +
Sbjct: 1241 DPEMEKEL-QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ--EILQ 1297
Query: 102 LLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL-LA 158
ED + EE A L K + Q+ +D + + + AR E+E S+ + V + +
Sbjct: 1298 FQEDPQTK-EEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVV 1356
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ E + S E +++ + ++ EL R + + L ++ EL +E Q
Sbjct: 1357 RYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQA 1412
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ V L+ ++A+ Q + +R+QLEEE
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1472
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R LE GE+ R K L + +
Sbjct: 1473 RQLLE-------GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEE 1525
Query: 339 VEKQKSRLQSEV---EVLIIDLEKANG-TARELQKRTE-----QLERVNIEIKS-RLEET 388
+ K L EV E + +LE N +++EL E QLER N+++++ RL+
Sbjct: 1526 ESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETRRLQSE 1585
Query: 389 VQLYEQTQRDLRNKQTELQRVSHE--LDKTREQKDALARENK 428
+ + RDLRN +H+ L + D L R +K
Sbjct: 1586 INMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSK 1627
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 61.3 bits (142), Expect = 8e-09
Identities = 81/463 (17%), Positives = 177/463 (38%), Gaps = 15/463 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + E LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L + + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
+++DLK + + + ++ +E +LE + L +
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEGAQGNLSQ 910
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
++ + L +L K E + K T
Sbjct: 911 TTQEQKQLSEKL-KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTL 969
Query: 335 KINN---VEKQKSR-----LQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++ N K+K+R +Q +++ ++ EK+ TA ++Q +E + + +
Sbjct: 970 ELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQD 1029
Query: 387 ETV---QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITX 443
E + QL EQT +DL + EL+ SH D + + ++ +L + R N
Sbjct: 1030 EALTKRQLLEQTLKDL---EYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDL 1086
Query: 444 XXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
AA ++ E G+ + E++++ L
Sbjct: 1087 LSERISRSREQMEQLRNGLLQERAARQDLECGKISLERQNKDL 1129
Score = 58.4 bits (135), Expect = 6e-08
Identities = 59/284 (20%), Positives = 112/284 (39%), Gaps = 13/284 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + E + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + EK G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
++K ++ +ET++ YE R L ++ E R
Sbjct: 851 QIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR 894
Score = 44.8 bits (101), Expect = 7e-04
Identities = 57/272 (20%), Positives = 113/272 (41%), Gaps = 22/272 (8%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 ------NIELVKEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
++L++E + L+ E + +Q+ Q + Q+
Sbjct: 817 QAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQL 876
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEI 293
E L R + +E AR LE +L A G +
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEGAQGNL 908
Score = 43.2 bits (97), Expect = 0.002
Identities = 45/203 (22%), Positives = 101/203 (49%), Gaps = 13/203 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 1038 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERISRSREQ 1097
Query: 94 TELLKLRKLLEDVHLESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKE--KSKFQ 150
E L+ L E + E + L+++N+ D + +I L + R+ KE + +
Sbjct: 1098 MEQLRNGLLQERAARQDLECGKISLERQNK----DLKSRIIHL-EGSYRSSKEGLVVQME 1152
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 1153 ARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLSLRLK 1209
Query: 211 ELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 1210 AMKRQVEEAEEEIDRLESSKKKL 1232
Score = 42.3 bits (95), Expect = 0.004
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 888 KEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 947
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 948 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 1000
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 1001 E---KSRLTAMKMQDGMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 1053
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ ++ + + +E +R L +E AR
Sbjct: 1054 HLKDDRSRLVKQMEAKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNGLLQERAARQ 1113
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 1114 DLECGKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 1173
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 1174 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 1226
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 1227 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 1257
Score = 37.5 bits (83), Expect = 0.11
Identities = 43/197 (21%), Positives = 94/197 (47%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + + KE+ LE +EL L++T + ++L +E
Sbjct: 869 YEGEIRQLEEALVHARKEEKEAVSARRALE---NELEGAQGNLSQTTQEQKQLSEKLKEE 925
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 926 S-EQKEQLRRLKNEMEN 941
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 1137 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 1196
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 1197 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255
Query: 167 KITISK 172
+ + K
Sbjct: 1256 DLRLKK 1261
Score = 33.9 bits (74), Expect = 1.4
Identities = 40/195 (20%), Positives = 88/195 (45%), Gaps = 18/195 (9%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
+Y A+L AL + + ++E E+++A ++V L E E+ +G +E
Sbjct: 784 QYDAELQAL---RESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSE- 839
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
E+ R+ + +L++ +ED+ + + LKK ++ +I QL + A K
Sbjct: 840 --ELERR----VAQLQRQIEDLKGDEAKAKETLKK--------YEGEIRQLEEALVHARK 885
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E+ + + L ++E ++ ++L + E + E+L R ++ + +
Sbjct: 886 EEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWH 945
Query: 205 LSQENIELVKEVQDL 219
L + +L KE+ D+
Sbjct: 946 LGKTIEKLQKEMADI 960
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
>AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens
cDNA FLJ43937 fis, clone TESTI4013924. ).
Length = 623
Score = 61.3 bits (142), Expect = 8e-09
Identities = 55/182 (30%), Positives = 91/182 (50%), Gaps = 16/182 (8%)
Query: 58 EREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL- 116
ER+ ADL Q+ +L+ E+A AE ++ + + K ED+ L+++E+
Sbjct: 72 ERKHADL--QISELTRHAEDATKQAERYLSELQQSEALKEEAEKRREDLKLKAQESIRQW 129
Query: 117 -LKKKNQEIVIDFQ-EQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTC 174
LK K E ++ Q E +D+LT + KEK + + ++Y L Q+EN+ KE ++
Sbjct: 130 KLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKE---LNDVL 186
Query: 175 ERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIA 234
+ + ELH K E+L DI SH+ L E VK D +E+ + +S+I
Sbjct: 187 TKRALQEEELHSKEEKLR----DIKSHQADLELE----VKNSLDTIHRLESELKKQSKIQ 238
Query: 235 SQ 236
SQ
Sbjct: 239 SQ 240
Score = 39.5 bits (88), Expect = 0.028
Identities = 41/196 (20%), Positives = 91/196 (46%), Gaps = 26/196 (13%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
R++ + +LE + +R ++EKA L+ QV L+ LE E K+
Sbjct: 5 RVQLNFSAMASELEEVKRCMERKDKEKAHLASQVENLTRELENGE-----------KQQL 53
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++L K +++ H ++ E ++K+ ++ QI +LT+ A K+ ++ +E+
Sbjct: 54 QMLDRLKEIQN-HFDTCEA----ERKHADL------QISELTRHAEDATKQAERYLSELQ 102
Query: 155 ELLAQVENVTKE----KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ A E K K+ ++ + ++ +L +E+ + T+ ++T ++ +E
Sbjct: 103 QSEALKEEAEKRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKD 162
Query: 211 ELVKEVQDLKVNIENV 226
EL ++ IEN+
Sbjct: 163 ELKTQLYAALQQIENL 178
Score = 38.3 bits (85), Expect = 0.064
Identities = 36/187 (19%), Positives = 87/187 (46%), Gaps = 7/187 (3%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK-RDTELLKLRK 101
+ + L E ++ + ++ +DL+ Q ++ +E +Q ++ R EL L
Sbjct: 283 LANKLAEEERAKKAVLKDLSDLTAQ----AKSRDEETATIITQLKLERDVHQRELKDLTS 338
Query: 102 LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF-QAEVYELLAQV 160
L+ V + E+ L K ++ + + I L K ++ EK +K + ++ +L +Q
Sbjct: 339 SLQSVKTKHEQNIQELMKHFKKEKSEAENHIRTL-KAESLEEKNMAKIHRGQLEKLKSQC 397
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
+ +T+E ++L++ L ++EE + I H +R+ + ++L ++ L+
Sbjct: 398 DRLTEELTQNENENKKLKLKYQCLKDQLEEREKHISIEEEHLRRMEEARLQLKDQLLCLE 457
Query: 221 VNIENVV 227
E+++
Sbjct: 458 TEQESIL 464
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 61.3 bits (142), Expect = 8e-09
Identities = 76/409 (18%), Positives = 173/409 (42%), Gaps = 28/409 (6%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + + +Q+D + + +LR++ E E + L ++ +L + AEG + + ++D
Sbjct: 1065 QLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDA 1124
Query: 95 ----ELLKLRKLLED----VHLESEETAHLLKK------KNQEIVIDFQEQIDQLTKTKA 140
E+ L + ED E LL+K +N ++V+ QE++ ++ +
Sbjct: 1125 ATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVV--QEKVREIVRPDP 1182
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK--IEELNRTIVDI 198
+AE E + + E+ E + ++ + E L ++ +K +E+ + D
Sbjct: 1183 KAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDP 1242
Query: 199 TSHK--QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K QRL +E ++ + ++ + ++E + LK +I +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIE--RCDLE-IYQLKKEIQALKDTKPQVQTKEVVQEILQFQ 1299
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
Q + ++ S+R +L EE + ++DLER+ +I +
Sbjct: 1300 EDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYE 1359
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ ++ ++ ++K ++ L+ ++ +LE+ EL++ +
Sbjct: 1360 EEPGLRAEASAFAESIDVELRQIDKLRAELR-RLQRRRTELERQ---LEELERERQARRE 1415
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
E++ RL++ + EQ + + R K T Q+V + D + ++ AL R
Sbjct: 1416 AEREVQ-RLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1463
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 8/203 (3%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+L L R ++ ++LE ER+ R+ ERE L ++ L + EA +
Sbjct: 1387 AELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQK 1446
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHL-----LKKKNQEIVIDFQEQIDQLTKTKARA 142
+ ++D + + LL + LE E+ L+ +++ + ++ +
Sbjct: 1447 VVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1505
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI--VDITS 200
+ EK + E+ L + +E ++ K + RLE +SEL + ++ + + +
Sbjct: 1506 QVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREEN 1565
Query: 201 HKQRLSQENIELVKEVQDLKVNI 223
HK +L ++N++L ++N+
Sbjct: 1566 HKLQLERQNLQLETRRLQSEINM 1588
Score = 41.1 bits (92), Expect = 0.009
Identities = 84/402 (20%), Positives = 157/402 (39%), Gaps = 34/402 (8%)
Query: 46 DLESERELRQRIEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
D E E+EL QR+ E D + + +++ + +E + +++ ++ K + ++ +
Sbjct: 1241 DPEMEKEL-QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ--EILQ 1297
Query: 102 LLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL-LA 158
ED + EE A L K + Q+ +D + + + AR E+E S+ + V + +
Sbjct: 1298 FQEDPQTK-EEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVV 1356
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ E + S E +++ + ++ EL R + + L ++ EL +E Q
Sbjct: 1357 RYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQA 1412
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ V L+ ++A+ Q + +R+QLEEE
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1472
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R LE GE+ R K L + +
Sbjct: 1473 RQLLE-------GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEE 1525
Query: 339 VEKQKSRLQSEV---EVLIIDLEKANG-TARELQKRTE-----QLERVNIEIKS-RLEET 388
+ K L EV E + +LE N +++EL E QLER N+++++ RL+
Sbjct: 1526 ESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSE 1585
Query: 389 VQLYEQTQRDLRNKQTELQRVSHE--LDKTREQKDALARENK 428
+ + RDLRN +H+ L + D L R +K
Sbjct: 1586 INMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSK 1627
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 61.3 bits (142), Expect = 8e-09
Identities = 76/409 (18%), Positives = 173/409 (42%), Gaps = 28/409 (6%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + + +Q+D + + +LR++ E E + L ++ +L + AEG + + ++D
Sbjct: 1065 QLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDA 1124
Query: 95 ----ELLKLRKLLED----VHLESEETAHLLKK------KNQEIVIDFQEQIDQLTKTKA 140
E+ L + ED E LL+K +N ++V+ QE++ ++ +
Sbjct: 1125 ATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVV--QEKVREIVRPDP 1182
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK--IEELNRTIVDI 198
+AE E + + E+ E + ++ + E L ++ +K +E+ + D
Sbjct: 1183 KAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDP 1242
Query: 199 TSHK--QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K QRL +E ++ + ++ + ++E + LK +I +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIE--RCDLE-IYQLKKEIQALKDTKPQVQTKEVVQEILQFQ 1299
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
Q + ++ S+R +L EE + ++DLER+ +I +
Sbjct: 1300 EDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYE 1359
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ ++ ++ ++K ++ L+ ++ +LE+ EL++ +
Sbjct: 1360 EEPGLRAEASAFAESIDVELRQIDKLRAELR-RLQRRRTELERQ---LEELERERQARRE 1415
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
E++ RL++ + EQ + + R K T Q+V + D + ++ AL R
Sbjct: 1416 AEREVQ-RLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1463
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 8/203 (3%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+L L R ++ ++LE ER+ R+ ERE L ++ L + EA +
Sbjct: 1387 AELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQK 1446
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHL-----LKKKNQEIVIDFQEQIDQLTKTKARA 142
+ ++D + + LL + LE E+ L+ +++ + ++ +
Sbjct: 1447 VVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1505
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI--VDITS 200
+ EK + E+ L + +E ++ K + RLE +SEL + ++ + + +
Sbjct: 1506 QVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREEN 1565
Query: 201 HKQRLSQENIELVKEVQDLKVNI 223
HK +L ++N++L ++N+
Sbjct: 1566 HKLQLERQNLQLETRRLQSEINM 1588
Score = 41.1 bits (92), Expect = 0.009
Identities = 84/402 (20%), Positives = 157/402 (39%), Gaps = 34/402 (8%)
Query: 46 DLESERELRQRIEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
D E E+EL QR+ E D + + +++ + +E + +++ ++ K + ++ +
Sbjct: 1241 DPEMEKEL-QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ--EILQ 1297
Query: 102 LLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL-LA 158
ED + EE A L K + Q+ +D + + + AR E+E S+ + V + +
Sbjct: 1298 FQEDPQTK-EEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVV 1356
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ E + S E +++ + ++ EL R + + L ++ EL +E Q
Sbjct: 1357 RYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQA 1412
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ V L+ ++A+ Q + +R+QLEEE
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1472
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R LE GE+ R K L + +
Sbjct: 1473 RQLLE-------GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEE 1525
Query: 339 VEKQKSRLQSEV---EVLIIDLEKANG-TARELQKRTE-----QLERVNIEIKS-RLEET 388
+ K L EV E + +LE N +++EL E QLER N+++++ RL+
Sbjct: 1526 ESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSE 1585
Query: 389 VQLYEQTQRDLRNKQTELQRVSHE--LDKTREQKDALARENK 428
+ + RDLRN +H+ L + D L R +K
Sbjct: 1586 INMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSK 1627
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 61.3 bits (142), Expect = 8e-09
Identities = 76/409 (18%), Positives = 173/409 (42%), Gaps = 28/409 (6%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + + +Q+D + + +LR++ E E + L ++ +L + AEG + + ++D
Sbjct: 1065 QLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDA 1124
Query: 95 ----ELLKLRKLLED----VHLESEETAHLLKK------KNQEIVIDFQEQIDQLTKTKA 140
E+ L + ED E LL+K +N ++V+ QE++ ++ +
Sbjct: 1125 ATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVV--QEKVREIVRPDP 1182
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK--IEELNRTIVDI 198
+AE E + + E+ E + ++ + E L ++ +K +E+ + D
Sbjct: 1183 KAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDP 1242
Query: 199 TSHK--QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K QRL +E ++ + ++ + ++E + LK +I +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIE--RCDLE-IYQLKKEIQALKDTKPQVQTKEVVQEILQFQ 1299
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
Q + ++ S+R +L EE + ++DLER+ +I +
Sbjct: 1300 EDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYE 1359
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ ++ ++ ++K ++ L+ ++ +LE+ EL++ +
Sbjct: 1360 EEPGLRAEASAFAESIDVELRQIDKLRAELR-RLQRRRTELERQ---LEELERERQARRE 1415
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
E++ RL++ + EQ + + R K T Q+V + D + ++ AL R
Sbjct: 1416 AEREVQ-RLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1463
Score = 47.6 bits (108), Expect = 1e-04
Identities = 41/203 (20%), Positives = 90/203 (44%), Gaps = 8/203 (3%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+L L R ++ ++LE ER+ R+ ERE L ++ L + EA +
Sbjct: 1387 AELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQK 1446
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHL-----LKKKNQEIVIDFQEQIDQLTKTKARA 142
+ ++D + + LL + LE E+ L+ +++ + ++ +
Sbjct: 1447 VVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1505
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI--VDITS 200
+ EK + E+ L + +E ++ K + RLE +SEL + ++ + + +
Sbjct: 1506 QVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREEN 1565
Query: 201 HKQRLSQENIELVKEVQDLKVNI 223
HK +L ++N++L ++N+
Sbjct: 1566 HKLQLERQNLQLETRRLQSEINM 1588
Score = 41.1 bits (92), Expect = 0.009
Identities = 84/402 (20%), Positives = 157/402 (39%), Gaps = 34/402 (8%)
Query: 46 DLESERELRQRIEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
D E E+EL QR+ E D + + +++ + +E + +++ ++ K + ++ +
Sbjct: 1241 DPEMEKEL-QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ--EILQ 1297
Query: 102 LLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL-LA 158
ED + EE A L K + Q+ +D + + + AR E+E S+ + V + +
Sbjct: 1298 FQEDPQTK-EEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVV 1356
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ E + S E +++ + ++ EL R + + L ++ EL +E Q
Sbjct: 1357 RYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQA 1412
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ V L+ ++A+ Q + +R+QLEEE
Sbjct: 1413 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1472
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R LE GE+ R K L + +
Sbjct: 1473 RQLLE-------GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEE 1525
Query: 339 VEKQKSRLQSEV---EVLIIDLEKANG-TARELQKRTE-----QLERVNIEIKS-RLEET 388
+ K L EV E + +LE N +++EL E QLER N+++++ RL+
Sbjct: 1526 ESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSE 1585
Query: 389 VQLYEQTQRDLRNKQTELQRVSHE--LDKTREQKDALARENK 428
+ + RDLRN +H+ L + D L R +K
Sbjct: 1586 INMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSK 1627
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 61.3 bits (142), Expect = 8e-09
Identities = 76/409 (18%), Positives = 173/409 (42%), Gaps = 28/409 (6%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+LE + + +Q+D + + +LR++ E E + L ++ +L + AEG + + ++D
Sbjct: 735 QLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDA 794
Query: 95 ----ELLKLRKLLED----VHLESEETAHLLKK------KNQEIVIDFQEQIDQLTKTKA 140
E+ L + ED E LL+K +N ++V+ QE++ ++ +
Sbjct: 795 ATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVV--QEKVREIVRPDP 852
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK--IEELNRTIVDI 198
+AE E + + E+ E + ++ + E L ++ +K +E+ + D
Sbjct: 853 KAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDP 912
Query: 199 TSHK--QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K QRL +E ++ + ++ + ++E + LK +I +
Sbjct: 913 EMEKELQRLREEIVDKTRLIE--RCDLE-IYQLKKEIQALKDTKPQVQTKEVVQEILQFQ 969
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
Q + ++ S+R +L EE + ++DLER+ +I +
Sbjct: 970 EDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYE 1029
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ ++ ++ ++K ++ L+ ++ +LE+ EL++ +
Sbjct: 1030 EEPGLRAEASAFAESIDVELRQIDKLRAELR-RLQRRRTELERQ---LEELERERQARRE 1085
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
E++ RL++ + EQ + + R K T Q+V + D + ++ AL R
Sbjct: 1086 AEREVQ-RLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR 1133
Score = 48.8 bits (111), Expect = 5e-05
Identities = 42/203 (20%), Positives = 90/203 (44%), Gaps = 8/203 (3%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+L L R ++ ++LE ER+ R+ ERE L ++ L + EA +
Sbjct: 1057 AELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQK 1116
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHL-----LKKKNQEIVIDFQEQIDQLTKTKARA 142
+ ++D + + LL + LE E+ L+ +++ + ++ +
Sbjct: 1117 VVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESV 1175
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI--VDITS 200
+ EK + E+ L + +E ++ K + RLE +SEL + ++ + + +
Sbjct: 1176 QVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREEN 1235
Query: 201 HKQRLSQENIELVKEVQDLKVNI 223
HK +L +EN++L ++N+
Sbjct: 1236 HKLQLERENLQLETRRLQSEINM 1258
Score = 41.1 bits (92), Expect = 0.009
Identities = 84/402 (20%), Positives = 157/402 (39%), Gaps = 34/402 (8%)
Query: 46 DLESERELRQRIEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELLKLRK 101
D E E+EL QR+ E D + + +++ + +E + +++ ++ K + ++ +
Sbjct: 911 DPEMEKEL-QRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQ--EILQ 967
Query: 102 LLEDVHLESEETAHLLKK--KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL-LA 158
ED + EE A L K + Q+ +D + + + AR E+E S+ + V + +
Sbjct: 968 FQEDPQTK-EEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVV 1026
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ E + S E +++ + ++ EL R + + L ++ EL +E Q
Sbjct: 1027 RYEEEPGLRAEASAFAESIDVELRQIDKLRAELRR----LQRRRTELERQLEELERERQA 1082
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ V L+ ++A+ Q + +R+QLEEE
Sbjct: 1083 RREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHR 1142
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R LE GE+ R K L + +
Sbjct: 1143 RQLLE-------GELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEE 1195
Query: 339 VEKQKSRLQSEV---EVLIIDLEKANG-TARELQKRTE-----QLERVNIEIKS-RLEET 388
+ K L EV E + +LE N +++EL E QLER N+++++ RL+
Sbjct: 1196 ESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETRRLQSE 1255
Query: 389 VQLYEQTQRDLRNKQTELQRVSHE--LDKTREQKDALARENK 428
+ + RDLRN +H+ L + D L R +K
Sbjct: 1256 INMAATETRDLRNMTVADSGTNHDSRLWSLERELDDLKRLSK 1297
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 60.9 bits (141), Expect = 1e-08
Identities = 78/402 (19%), Positives = 154/402 (38%), Gaps = 6/402 (1%)
Query: 29 DLSALSRLEDKIRLI-QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
+LS ++L L Q +++++ E+ + ++K L Q +L + + E E
Sbjct: 825 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH 884
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAEKEK 146
+ LL+L L +V LE EE LK++ E+ + QE+ QLT + ARA E
Sbjct: 885 QDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 944
Query: 147 SKFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
QA E+ E A+ E + +R + I +L + +T
Sbjct: 945 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 1004
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L+ +N L K++ + + +V L+S++ +L
Sbjct: 1005 LNNQNFYLSKQLDEASGANDEIVQLRSEV-DHLRREITEREMQLTSQKQTMEALKTTCTM 1063
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE + LE ++ L+ ERQ +G +S+F +
Sbjct: 1064 LEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQR 1123
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
+ + + + LQ ++ + E + +L+K+ LE ++ +
Sbjct: 1124 ITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQK 1183
Query: 385 LEETVQLYEQTQRDLRNKQTELQ-RVSHELDKTREQKDALAR 425
LE +L ++ + Q ++ + +H T+ ++AL R
Sbjct: 1184 LETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDR 1225
Score = 36.7 bits (81), Expect = 0.19
Identities = 47/272 (17%), Positives = 97/272 (35%), Gaps = 6/272 (2%)
Query: 164 TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
+KE C ++E ++ LH ++ E+ ++ + + S+ L++ QDL I
Sbjct: 455 SKELQDSQDKCHKMEQEMTRLHRRVSEVE-AVLSQKEVELKASETQRSLLE--QDLATYI 511
Query: 224 ENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV-EIDLESVRVQLEEESEARLDL 282
LK + ++ EI + + Q+EE L
Sbjct: 512 TECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQL 571
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
E LV A + S+ + + + +EK
Sbjct: 572 EEDLVSARRRSDLYESELRESRLAAEEFKRKAT-ECQHKLLKAKDQGKPEVGEYAKLEKI 630
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
+ Q +++ L LEKA + E + + + + + LE+ +Q E + +R K
Sbjct: 631 NAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEK-LQNREDSSEGIRKK 689
Query: 403 QTELQRVSHELDKTREQKDALARENKKMGDDL 434
E + H L+ ++ + + R ++ DD+
Sbjct: 690 LVEAEERRHSLENKVKRLETMERRENRLKDDI 721
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 60.9 bits (141), Expect = 1e-08
Identities = 78/402 (19%), Positives = 154/402 (38%), Gaps = 6/402 (1%)
Query: 29 DLSALSRLEDKIRLI-QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
+LS ++L L Q +++++ E+ + ++K L Q +L + + E E
Sbjct: 783 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH 842
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAEKEK 146
+ LL+L L +V LE EE LK++ E+ + QE+ QLT + ARA E
Sbjct: 843 QDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 902
Query: 147 SKFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
QA E+ E A+ E + +R + I +L + +T
Sbjct: 903 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 962
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L+ +N L K++ + + +V L+S++ +L
Sbjct: 963 LNNQNFYLSKQLDEASGANDEIVQLRSEV-DHLRREITEREMQLTSQKQTMEALKTTCTM 1021
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE + LE ++ L+ ERQ +G +S+F +
Sbjct: 1022 LEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQR 1081
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
+ + + + LQ ++ + E + +L+K+ LE ++ +
Sbjct: 1082 ITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQK 1141
Query: 385 LEETVQLYEQTQRDLRNKQTELQ-RVSHELDKTREQKDALAR 425
LE +L ++ + Q ++ + +H T+ ++AL R
Sbjct: 1142 LETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDR 1183
Score = 45.6 bits (103), Expect = 4e-04
Identities = 72/405 (17%), Positives = 165/405 (40%), Gaps = 28/405 (6%)
Query: 51 RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL------E 104
+EL++++E+ S + +L + + +A+ AE + E + R+ +RK L E
Sbjct: 639 QELQEKLEKA-VKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELE 697
Query: 105 DVHLESEETA-HL---LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
+ H E++ +A HL LK+K Q + +Q+ K A E ++ Q E +
Sbjct: 698 EKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKG 757
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
+ ++++K I+ ++ ++ + +++ E N+ + + QR + E++ E++ K
Sbjct: 758 KILSEQKAMINAMDSKIR-SLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQK 816
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
+E ++ +Q L ++E L V ++ EE+ +L
Sbjct: 817 FYLETQA---GKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ---KL 870
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXX---XXXXKYSXXXXXXXXXXXTLIAKIN 337
+L+RQL + + S+ + L A +
Sbjct: 871 ELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRD 930
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE---Q 394
++++ L++ V I DLE+ +L + +L N + +L+E + Q
Sbjct: 931 EIQRKFDALRNSCTV-ITDLEE---QLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQ 986
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ ++ + + E+ +L ++ +AL + + + D A
Sbjct: 987 LRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEA 1031
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 60.9 bits (141), Expect = 1e-08
Identities = 78/402 (19%), Positives = 154/402 (38%), Gaps = 6/402 (1%)
Query: 29 DLSALSRLEDKIRLI-QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
+LS ++L L Q +++++ E+ + ++K L Q +L + + E E
Sbjct: 57 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH 116
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAEKEK 146
+ LL+L L +V LE EE LK++ E+ + QE+ QLT + ARA E
Sbjct: 117 QDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 176
Query: 147 SKFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
QA E+ E A+ E + +R + I +L + +T
Sbjct: 177 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 236
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L+ +N L K++ + + +V L+S++ +L
Sbjct: 237 LNNQNFYLSKQLDEASGANDEIVQLRSEV-DHLRREITEREMQLTSQKQTMEALKTTCTM 295
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE + LE ++ L+ ERQ +G +S+F +
Sbjct: 296 LEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQR 355
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
+ + + + LQ ++ + E + +L+K+ LE ++ +
Sbjct: 356 ITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQK 415
Query: 385 LEETVQLYEQTQRDLRNKQTELQ-RVSHELDKTREQKDALAR 425
LE +L ++ + Q ++ + +H T+ ++AL R
Sbjct: 416 LETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDR 457
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 60.9 bits (141), Expect = 1e-08
Identities = 78/402 (19%), Positives = 154/402 (38%), Gaps = 6/402 (1%)
Query: 29 DLSALSRLEDKIRLI-QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
+LS ++L L Q +++++ E+ + ++K L Q +L + + E E
Sbjct: 331 ELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISH 390
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAEKEK 146
+ LL+L L +V LE EE LK++ E+ + QE+ QLT + ARA E
Sbjct: 391 QDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALES 450
Query: 147 SKFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
QA E+ E A+ E + +R + I +L + +T
Sbjct: 451 QLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAE 510
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L+ +N L K++ + + +V L+S++ +L
Sbjct: 511 LNNQNFYLSKQLDEASGANDEIVQLRSEV-DHLRREITEREMQLTSQKQTMEALKTTCTM 569
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
LE + LE ++ L+ ERQ +G +S+F +
Sbjct: 570 LEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQR 629
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
+ + + + LQ ++ + E + +L+K+ LE ++ +
Sbjct: 630 ITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQK 689
Query: 385 LEETVQLYEQTQRDLRNKQTELQ-RVSHELDKTREQKDALAR 425
LE +L ++ + Q ++ + +H T+ ++AL R
Sbjct: 690 LETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDR 731
Score = 45.6 bits (103), Expect = 4e-04
Identities = 72/405 (17%), Positives = 165/405 (40%), Gaps = 28/405 (6%)
Query: 51 RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL------E 104
+EL++++E+ S + +L + + +A+ AE + E + R+ +RK L E
Sbjct: 187 QELQEKLEKA-VKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELE 245
Query: 105 DVHLESEETA-HL---LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
+ H E++ +A HL LK+K Q + +Q+ K A E ++ Q E +
Sbjct: 246 EKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKG 305
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
+ ++++K I+ ++ ++ + +++ E N+ + + QR + E++ E++ K
Sbjct: 306 KILSEQKAMINAMDSKIR-SLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQK 364
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
+E ++ +Q L ++E L V ++ EE+ +L
Sbjct: 365 FYLETQA---GKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ---KL 418
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXX---XXXXKYSXXXXXXXXXXXTLIAKIN 337
+L+RQL + + S+ + L A +
Sbjct: 419 ELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRD 478
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE---Q 394
++++ L++ V I DLE+ +L + +L N + +L+E + Q
Sbjct: 479 EIQRKFDALRNSCTV-ITDLEE---QLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQ 534
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+ ++ + + E+ +L ++ +AL + + + D A
Sbjct: 535 LRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEA 579
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 60.1 bits (139), Expect = 2e-08
Identities = 71/275 (25%), Positives = 128/275 (46%), Gaps = 24/275 (8%)
Query: 36 LEDKIRLIQDDLES-ERELRQRIE------REKADLSVQVIQLSERLEEAEGG------- 81
L +K R+I+ E ER+ R+R+E +E DL +V L L E E
Sbjct: 590 LSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEH 649
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLLKKKNQE----IVIDFQEQIDQLT 136
A S KRD++L L +E E S+ A L K N E + +F +QI QL
Sbjct: 650 ASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLD 709
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + E K QAEV LL ++ V EK K LE +++ H+K + N+ +
Sbjct: 710 KEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE-SLTLRHMK--DQNKKVA 766
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNI-ENVVYLK-SQIASQXXXXXXXXXXXXXXXXXX 254
++ ++Q ++N +L++EV+ + ++ +N +L+ ++ +
Sbjct: 767 NLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLAST 826
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKA 289
SL + E L ++R++ ++ E L+++++ + A
Sbjct: 827 QQSLAEKEAHLANLRIERRKQLEEILEMKQEALLA 861
Score = 44.0 bits (99), Expect = 0.001
Identities = 86/474 (18%), Positives = 176/474 (37%), Gaps = 30/474 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQ--VIQLSERLEEAEGGAESQFEINRKRD 93
L+ I+ +QD+L ++R+L +++E + + I+L+E E Q E +R+
Sbjct: 221 LQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTE-----ENFRRLQAEHDRQA- 274
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAE 152
EL LRK LE++ L E L +++ I + Q L + E+++ AE
Sbjct: 275 KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAE 334
Query: 153 VYELLAQVENV----TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ +E + KE I + + R + K + L +T++++ K +
Sbjct: 335 AESQVSHLEVILDQKEKENIHLREELHR-RSQLQPEPAKTKAL-QTVIEMKDTKIASLER 392
Query: 209 NI-ELVKEVQDLKVN-IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
NI +L E+Q LK N + N + +I Q L + E +L
Sbjct: 393 NIRDLEDEIQMLKANGVLNTEDREEEI-KQIEVYKSHSKFMKTKIDQLKQELSKKESELL 451
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
+++ +LE S D ++ + + + K S
Sbjct: 452 ALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Query: 327 XXXXTLIAK---INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
K + K L+ + + + +K +L+ + +QL + +KS
Sbjct: 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD--------ALARENKKMGDDLH 435
L+ + L +E +R+ L + RE+ D + +ENK + + ++
Sbjct: 572 -LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVN 630
Query: 436 DARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
+A +T + K E + +++ +L A+
Sbjct: 631 ALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 684
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 60.1 bits (139), Expect = 2e-08
Identities = 71/275 (25%), Positives = 128/275 (46%), Gaps = 24/275 (8%)
Query: 36 LEDKIRLIQDDLES-ERELRQRIE------REKADLSVQVIQLSERLEEAEGG------- 81
L +K R+I+ E ER+ R+R+E +E DL +V L L E E
Sbjct: 590 LSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEH 649
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLLKKKNQE----IVIDFQEQIDQLT 136
A S KRD++L L +E E S+ A L K N E + +F +QI QL
Sbjct: 650 ASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLD 709
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + E K QAEV LL ++ V EK K LE +++ H+K + N+ +
Sbjct: 710 KEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE-SLTLRHMK--DQNKKVA 766
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNI-ENVVYLK-SQIASQXXXXXXXXXXXXXXXXXX 254
++ ++Q ++N +L++EV+ + ++ +N +L+ ++ +
Sbjct: 767 NLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLAST 826
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKA 289
SL + E L ++R++ ++ E L+++++ + A
Sbjct: 827 QQSLAEKEAHLANLRIERRKQLEEILEMKQEALLA 861
Score = 44.0 bits (99), Expect = 0.001
Identities = 86/474 (18%), Positives = 176/474 (37%), Gaps = 30/474 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQ--VIQLSERLEEAEGGAESQFEINRKRD 93
L+ I+ +QD+L ++R+L +++E + + I+L+E E Q E +R+
Sbjct: 221 LQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTE-----ENFRRLQAEHDRQA- 274
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAE 152
EL LRK LE++ L E L +++ I + Q L + E+++ AE
Sbjct: 275 KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAE 334
Query: 153 VYELLAQVENV----TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ +E + KE I + + R + K + L +T++++ K +
Sbjct: 335 AESQVSHLEVILDQKEKENIHLREELHR-RSQLQPEPAKTKAL-QTVIEMKDTKIASLER 392
Query: 209 NI-ELVKEVQDLKVN-IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
NI +L E+Q LK N + N + +I Q L + E +L
Sbjct: 393 NIRDLEDEIQMLKANGVLNTEDREEEI-KQIEVYKSHSKFMKTKIDQLKQELSKKESELL 451
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
+++ +LE S D ++ + + + K S
Sbjct: 452 ALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 511
Query: 327 XXXXTLIAK---INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
K + K L+ + + + +K +L+ + +QL + +KS
Sbjct: 512 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 571
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD--------ALARENKKMGDDLH 435
L+ + L +E +R+ L + RE+ D + +ENK + + ++
Sbjct: 572 -LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVN 630
Query: 436 DARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
+A +T + K E + +++ +L A+
Sbjct: 631 ALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 684
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 60.1 bits (139), Expect = 2e-08
Identities = 71/275 (25%), Positives = 128/275 (46%), Gaps = 24/275 (8%)
Query: 36 LEDKIRLIQDDLES-ERELRQRIE------REKADLSVQVIQLSERLEEAEGG------- 81
L +K R+I+ E ER+ R+R+E +E DL +V L L E E
Sbjct: 603 LSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEH 662
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLLKKKNQE----IVIDFQEQIDQLT 136
A S KRD++L L +E E S+ A L K N E + +F +QI QL
Sbjct: 663 ASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLD 722
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + E K QAEV LL ++ V EK K LE +++ H+K + N+ +
Sbjct: 723 KEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE-SLTLRHMK--DQNKKVA 779
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNI-ENVVYLK-SQIASQXXXXXXXXXXXXXXXXXX 254
++ ++Q ++N +L++EV+ + ++ +N +L+ ++ +
Sbjct: 780 NLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLAST 839
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKA 289
SL + E L ++R++ ++ E L+++++ + A
Sbjct: 840 QQSLAEKEAHLANLRIERRKQLEEILEMKQEALLA 874
Score = 44.0 bits (99), Expect = 0.001
Identities = 86/474 (18%), Positives = 176/474 (37%), Gaps = 30/474 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQ--VIQLSERLEEAEGGAESQFEINRKRD 93
L+ I+ +QD+L ++R+L +++E + + I+L+E E Q E +R+
Sbjct: 234 LQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTE-----ENFRRLQAEHDRQA- 287
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAE 152
EL LRK LE++ L E L +++ I + Q L + E+++ AE
Sbjct: 288 KELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAE 347
Query: 153 VYELLAQVENV----TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ +E + KE I + + R + K + L +T++++ K +
Sbjct: 348 AESQVSHLEVILDQKEKENIHLREELHR-RSQLQPEPAKTKAL-QTVIEMKDTKIASLER 405
Query: 209 NI-ELVKEVQDLKVN-IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
NI +L E+Q LK N + N + +I Q L + E +L
Sbjct: 406 NIRDLEDEIQMLKANGVLNTEDREEEI-KQIEVYKSHSKFMKTKIDQLKQELSKKESELL 464
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
+++ +LE S D ++ + + + K S
Sbjct: 465 ALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 524
Query: 327 XXXXTLIAK---INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
K + K L+ + + + +K +L+ + +QL + +KS
Sbjct: 525 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKS 584
Query: 384 RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD--------ALARENKKMGDDLH 435
L+ + L +E +R+ L + RE+ D + +ENK + + ++
Sbjct: 585 -LQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVN 643
Query: 436 DARANITXXXXXXXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAE 489
+A +T + K E + +++ +L A+
Sbjct: 644 ALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 697
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 59.3 bits (137), Expect = 3e-08
Identities = 84/418 (20%), Positives = 173/418 (41%), Gaps = 30/418 (7%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 589
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 590 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 638
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE---- 262
+EN L K++ +LK+ E + L+ Q S+ L +E
Sbjct: 639 KENELLQKKITNLKITCEKIEALE-QENSELERENRKLKKTLDSFKNLTFQLESLEKENS 697
Query: 263 -IDLESVRVQLEEESEARLDLE-RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+D E++ ++ ES ++ QL N E+ + + +
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLEV 756
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L + N K+ +L+SE++ L ++ + EL+ +++LE++ E
Sbjct: 757 SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 816
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA----LARENKKMGDDL 434
KS +ET QL E+ ++ L + L++ + D T E+ + L +ENK + ++
Sbjct: 817 NKSLEQETSQL-EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Score = 54.4 bits (125), Expect = 9e-07
Identities = 92/450 (20%), Positives = 194/450 (43%), Gaps = 48/450 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RL K+ ++++++ E++ Q + DL + QL + +E +E Q +I + +
Sbjct: 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 561
Query: 95 ELLK-LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT---KARAEKEKSKFQ 150
L + + L + + +E ++K+N+ + +E +L+K K + +KE ++
Sbjct: 562 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 621
Query: 151 AE---VYELLAQVENVTKE------KITISK-TCERLEITI---SELHIKIEELNRTI-- 195
+ EL ++ ++ KE KIT K TCE++E SEL + +L +T+
Sbjct: 622 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 681
Query: 196 -VDITSHKQRLSQENIELVKEVQDLKVNIENV--VYLK-SQIASQXXXXXXXXXXXXXXX 251
++T + L +EN +L +E +L+ N+E++ +K +Q+ +
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGL 741
Query: 252 XXXXASLHQVE--------IDLESVRVQ--LEEESEARLDLERQLVKANGEIGHWRSKFX 301
AS + E +D+E+ R+Q LE ++ LE +L E +
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 302 XXXXXXXXXXXXXXXKYS-XXXXXXXXXXXTLIAKINNVEKQKSRLQ----SEVEVLIID 356
S + K N +Q++ ++ E V I +
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 357 LEKAN-------GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LEK N G +E R ++LE+ N E+ R ++ + DL +++ + Q++
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARA 439
+++L+K + + + +++ LHD ++
Sbjct: 922 NNDLEKLTHELEKIGLNKERL---LHDEQS 948
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 357 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 407
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 408 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 585
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 641
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 702 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Score = 48.8 bits (111), Expect = 5e-05
Identities = 81/386 (20%), Positives = 159/386 (41%), Gaps = 29/386 (7%)
Query: 57 IEREKADLSVQVIQLSERLEEAE---GGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
IE+E L + + S +L + E + + E +++ +L L HLE E
Sbjct: 585 IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH--HLEKEN- 641
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV---YELLAQVENVTKEKITI 170
LL+KK + I E+I+ L + + E+E K + + L Q+E++ KE +
Sbjct: 642 -ELLQKKITNLKITC-EKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 171 SKTCERLEITISELH---IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ L + L +K+ +L ++ S K++L ++ +EL+K +E V
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLE-VS 757
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Y I +Q + L +E++ ++++ LEE + LE QL
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLE--SELQDLEMENQTLQKNLEELKISSKRLE-QLE 814
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
K N + S+ + KI N+EK+ L
Sbjct: 815 KENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN----VKIGNLEKENKTLS 870
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQL-ERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+ + +++ +EL+K ++L +R I+IK+ + L + + + +L
Sbjct: 871 KEIGIY----KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT-QQMNNDL 925
Query: 407 QRVSHELDKTREQKDALARENKKMGD 432
++++HEL+K K+ L + + D
Sbjct: 926 EKLTHELEKIGLNKERLLHDEQSTDD 951
Score = 45.6 bits (103), Expect = 4e-04
Identities = 85/423 (20%), Positives = 173/423 (40%), Gaps = 39/423 (9%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE--------GGAESQFEI 88
E+KI ++ LE Q++ +E + L +R +E G ++++E
Sbjct: 973 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER 1032
Query: 89 NRKRDT-ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ T ELLK++ L +E E L+ + Q + + Q+ QL E + +
Sbjct: 1033 ESQETTRELLKVKDRL----IEVERNNATLQAEKQAL----KTQLKQL-------ETQNN 1077
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
QA++ L Q ++ ++ T+ +L++ S L+ + L + + L
Sbjct: 1078 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1137
Query: 208 ENIELVKEVQDLKVNIENVV--YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE-ID 264
EN ++KE +DLK ++++ + K ++ + +VE D
Sbjct: 1138 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRD 1197
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK----YS- 319
LE QL ++ DLE+ L K E +K + YS
Sbjct: 1198 LEDRYNQLLKQKGQLEDLEKML-KVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQ 1256
Query: 320 --XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L + +NN + +++RL++E L ++ + T+ +L + E L ++
Sbjct: 1257 LLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQL 1316
Query: 378 --NIEIKSR-LEETVQLYEQTQRDLRNKQTELQRVSH-ELDKTREQKDALARENKKMGDD 433
N+E ++R L + +Q R L + E + + H E + ++ + L R+ +K+ +
Sbjct: 1317 KGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1376
Query: 434 LHD 436
+ D
Sbjct: 1377 IMD 1379
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 198 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 257
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 258 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 313
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 314 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 365
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 366 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 425 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 477
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 536
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 537 QLEKTIE 543
Score = 39.5 bits (88), Expect = 0.028
Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 29/241 (12%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE------ 76
N ++ ++L ++ + Q LE+E E + + L +I+ E+LE
Sbjct: 1111 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1170
Query: 77 --EAEG---------GAESQFEINRK----RDTELLKLRKLLEDVH--LESEETAHLLKK 119
E E A E+ + R +LLK + LED+ L+ E+ LL+
Sbjct: 1171 ASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLEN 1230
Query: 120 KNQEIVIDFQEQI----DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
KN E V +++ D+L T ++ KE Q + L + + N E+ +
Sbjct: 1231 KNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFS 1290
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+L+ +L I +LN ++ K L +EN L+ ++Q L ++N L+ + S
Sbjct: 1291 KLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLM--LQNRTLLEQNMES 1348
Query: 236 Q 236
+
Sbjct: 1349 K 1349
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 551 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 604
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 59.3 bits (137), Expect = 3e-08
Identities = 83/418 (19%), Positives = 173/418 (41%), Gaps = 30/418 (7%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 468 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 527
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 528 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 586
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 587 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 635
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE---- 262
+EN L K++ +LK+ E + L+ + S+ L +E
Sbjct: 636 KENELLQKKITNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKENS 694
Query: 263 -IDLESVRVQLEEESEARLDLER-QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+D E++ ++ ES ++ QL N E+ + + +
Sbjct: 695 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTE-RLEV 753
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L + N K+ +L+SE++ L ++ + EL+ +++LE++ E
Sbjct: 754 SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 813
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA----LARENKKMGDDL 434
KS +ET QL E+ ++ L + L++ + D T E+ + L +ENK + ++
Sbjct: 814 NKSLEQETSQL-EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 870
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 354 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 404
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 405 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 464
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 465 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 524
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 525 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 582
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 583 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 638
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 639 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 698
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 699 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 751
Score = 45.6 bits (103), Expect = 4e-04
Identities = 57/224 (25%), Positives = 104/224 (46%), Gaps = 30/224 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----------IEREKADLSVQVIQLSERLEEAEG 80
S LS++E + R I+ +LE +E +R +E+E L ++ L E+ E
Sbjct: 598 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 657
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQIDQLTKT 138
+ E+ R E KL+K L+ + + L K+ +Q E ++ + ++ L
Sbjct: 658 LEQENSELER----ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC- 712
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTK--EKITIS-KTCERLEITISELHIK-------I 188
A + ++ Q E EL ++ E + K E + S K ERLE++ L I+ +
Sbjct: 713 ---ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTL 769
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQ 232
E N+ I + S Q L EN L K +++LK++ + + L+ +
Sbjct: 770 ENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 813
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 195 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 254
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 255 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 310
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 311 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 362
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 363 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 421
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 422 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 474
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 475 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 533
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 534 QLEKTIE 540
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 488 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 547
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 548 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 601
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 59.3 bits (137), Expect = 3e-08
Identities = 84/418 (20%), Positives = 173/418 (41%), Gaps = 30/418 (7%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 589
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 590 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 638
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE---- 262
+EN L K++ +LK+ E + L+ Q S+ L +E
Sbjct: 639 KENELLQKKITNLKITCEKIEALE-QENSELERENRKLKKTLDSFKNLTFQLESLEKENS 697
Query: 263 -IDLESVRVQLEEESEARLDLE-RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+D E++ ++ ES ++ QL N E+ + + +
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLEV 756
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L + N K+ +L+SE++ L ++ + EL+ +++LE++ E
Sbjct: 757 SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 816
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA----LARENKKMGDDL 434
KS +ET QL E+ ++ L + L++ + D T E+ + L +ENK + ++
Sbjct: 817 NKSLEQETSQL-EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Score = 54.4 bits (125), Expect = 9e-07
Identities = 92/450 (20%), Positives = 194/450 (43%), Gaps = 48/450 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RL K+ ++++++ E++ Q + DL + QL + +E +E Q +I + +
Sbjct: 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 561
Query: 95 ELLK-LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT---KARAEKEKSKFQ 150
L + + L + + +E ++K+N+ + +E +L+K K + +KE ++
Sbjct: 562 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 621
Query: 151 AE---VYELLAQVENVTKE------KITISK-TCERLEITI---SELHIKIEELNRTI-- 195
+ EL ++ ++ KE KIT K TCE++E SEL + +L +T+
Sbjct: 622 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 681
Query: 196 -VDITSHKQRLSQENIELVKEVQDLKVNIENV--VYLK-SQIASQXXXXXXXXXXXXXXX 251
++T + L +EN +L +E +L+ N+E++ +K +Q+ +
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGL 741
Query: 252 XXXXASLHQVE--------IDLESVRVQ--LEEESEARLDLERQLVKANGEIGHWRSKFX 301
AS + E +D+E+ R+Q LE ++ LE +L E +
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 302 XXXXXXXXXXXXXXXKYS-XXXXXXXXXXXTLIAKINNVEKQKSRLQ----SEVEVLIID 356
S + K N +Q++ ++ E V I +
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 357 LEKAN-------GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LEK N G +E R ++LE+ N E+ R ++ + DL +++ + Q++
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARA 439
+++L+K + + + +++ LHD ++
Sbjct: 922 NNDLEKLTHELEKIGLNKERL---LHDEQS 948
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 357 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 407
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 408 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 585
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 641
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 702 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Score = 48.8 bits (111), Expect = 5e-05
Identities = 81/386 (20%), Positives = 159/386 (41%), Gaps = 29/386 (7%)
Query: 57 IEREKADLSVQVIQLSERLEEAE---GGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
IE+E L + + S +L + E + + E +++ +L L HLE E
Sbjct: 585 IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH--HLEKEN- 641
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV---YELLAQVENVTKEKITI 170
LL+KK + I E+I+ L + + E+E K + + L Q+E++ KE +
Sbjct: 642 -ELLQKKITNLKITC-EKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 171 SKTCERLEITISELH---IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ L + L +K+ +L ++ S K++L ++ +EL+K +E V
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLE-VS 757
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Y I +Q + L +E++ ++++ LEE + LE QL
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLE--SELQDLEMENQTLQKNLEELKISSKRLE-QLE 814
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
K N + S+ + KI N+EK+ L
Sbjct: 815 KENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN----VKIGNLEKENKTLS 870
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQL-ERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+ + +++ +EL+K ++L +R I+IK+ + L + + + +L
Sbjct: 871 KEIGIY----KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT-QQMNNDL 925
Query: 407 QRVSHELDKTREQKDALARENKKMGD 432
++++HEL+K K+ L + + D
Sbjct: 926 EKLTHELEKIGLNKERLLHDEQSTDD 951
Score = 46.4 bits (105), Expect = 2e-04
Identities = 86/430 (20%), Positives = 178/430 (41%), Gaps = 31/430 (7%)
Query: 37 EDKIRLIQDDLESERELRQRIEREK-ADLSVQVIQ---LSERLEEAEGGAESQFEINRKR 92
+D+ +L++ LES + I+ EK A L ++ + +++L + + +E ++R
Sbjct: 950 DDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR 1009
Query: 93 DTELLKLRKLL----EDVHLESEE---TAHLLKKKNQEIVID-----FQEQIDQLTKTKA 140
E ++ ED E E T LLK K++ I ++ Q + L
Sbjct: 1010 QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLK 1069
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ E + + QA++ L Q ++ ++ T+ +L++ S L+ + L +
Sbjct: 1070 QLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLI 1129
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVV--YLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+ L EN ++KE +DLK ++++ + K ++ +
Sbjct: 1130 QQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1189
Query: 259 HQVE-IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
+VE DLE QL ++ DLE+ L K E +K +
Sbjct: 1190 LEVEHRDLEDRYNQLLKQKGQLEDLEKML-KVEQEKMLLENKNHETVAAEYKKLCGENDR 1248
Query: 318 ----YS---XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR 370
YS L + +NN + +++RL++E L ++ + T+ +L +
Sbjct: 1249 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQ 1308
Query: 371 TEQLERV--NIEIKSR-LEETVQLYEQTQRDLRNKQTELQRVSH-ELDKTREQKDALARE 426
E L ++ N+E ++R L + +Q R L + E + + H E + ++ + L R+
Sbjct: 1309 CELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQ 1368
Query: 427 NKKMGDDLHD 436
+K+ + + D
Sbjct: 1369 KEKLEEKIMD 1378
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 198 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 257
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 258 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 313
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 314 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 365
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 366 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 425 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 477
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 536
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 537 QLEKTIE 543
Score = 39.5 bits (88), Expect = 0.028
Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 29/241 (12%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE------ 76
N ++ ++L ++ + Q LE+E E + + L +I+ E+LE
Sbjct: 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Query: 77 --EAEG---------GAESQFEINRK----RDTELLKLRKLLEDVH--LESEETAHLLKK 119
E E A E+ + R +LLK + LED+ L+ E+ LL+
Sbjct: 1170 ASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLEN 1229
Query: 120 KNQEIVIDFQEQI----DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
KN E V +++ D+L T ++ KE Q + L + + N E+ +
Sbjct: 1230 KNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFS 1289
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+L+ +L I +LN ++ K L +EN L+ ++Q L ++N L+ + S
Sbjct: 1290 KLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLM--LQNRTLLEQNMES 1347
Query: 236 Q 236
+
Sbjct: 1348 K 1348
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 551 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 604
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 59.3 bits (137), Expect = 3e-08
Identities = 84/418 (20%), Positives = 173/418 (41%), Gaps = 30/418 (7%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 471 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 530
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 531 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 589
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 590 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 638
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE---- 262
+EN L K++ +LK+ E + L+ Q S+ L +E
Sbjct: 639 KENELLQKKITNLKITCEKIEALE-QENSELERENRKLKKTLDSFKNLTFQLESLEKENS 697
Query: 263 -IDLESVRVQLEEESEARLDLE-RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+D E++ ++ ES ++ QL N E+ + + +
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLEV 756
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L + N K+ +L+SE++ L ++ + EL+ +++LE++ E
Sbjct: 757 SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKE 816
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDA----LARENKKMGDDL 434
KS +ET QL E+ ++ L + L++ + D T E+ + L +ENK + ++
Sbjct: 817 NKSLEQETSQL-EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Score = 54.4 bits (125), Expect = 9e-07
Identities = 92/450 (20%), Positives = 194/450 (43%), Gaps = 48/450 (10%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RL K+ ++++++ E++ Q + DL + QL + +E +E Q +I + +
Sbjct: 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 561
Query: 95 ELLK-LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT---KARAEKEKSKFQ 150
L + + L + + +E ++K+N+ + +E +L+K K + +KE ++
Sbjct: 562 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 621
Query: 151 AE---VYELLAQVENVTKE------KITISK-TCERLEITI---SELHIKIEELNRTI-- 195
+ EL ++ ++ KE KIT K TCE++E SEL + +L +T+
Sbjct: 622 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 681
Query: 196 -VDITSHKQRLSQENIELVKEVQDLKVNIENV--VYLK-SQIASQXXXXXXXXXXXXXXX 251
++T + L +EN +L +E +L+ N+E++ +K +Q+ +
Sbjct: 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGL 741
Query: 252 XXXXASLHQVE--------IDLESVRVQ--LEEESEARLDLERQLVKANGEIGHWRSKFX 301
AS + E +D+E+ R+Q LE ++ LE +L E +
Sbjct: 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 302 XXXXXXXXXXXXXXXKYS-XXXXXXXXXXXTLIAKINNVEKQKSRLQ----SEVEVLIID 356
S + K N +Q++ ++ E V I +
Sbjct: 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGN 861
Query: 357 LEKAN-------GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LEK N G +E R ++LE+ N E+ R ++ + DL +++ + Q++
Sbjct: 862 LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQM 921
Query: 410 SHELDKTREQKDALARENKKMGDDLHDARA 439
+++L+K + + + +++ LHD ++
Sbjct: 922 NNDLEKLTHELEKIGLNKERL---LHDEQS 948
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 357 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 407
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 408 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 467
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 585
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 586 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 641
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 701
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 702 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Score = 48.8 bits (111), Expect = 5e-05
Identities = 81/386 (20%), Positives = 159/386 (41%), Gaps = 29/386 (7%)
Query: 57 IEREKADLSVQVIQLSERLEEAE---GGAESQFEINRKRDTELLKLRKLLEDVHLESEET 113
IE+E L + + S +L + E + + E +++ +L L HLE E
Sbjct: 585 IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH--HLEKEN- 641
Query: 114 AHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV---YELLAQVENVTKEKITI 170
LL+KK + I E+I+ L + + E+E K + + L Q+E++ KE +
Sbjct: 642 -ELLQKKITNLKITC-EKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQL 699
Query: 171 SKTCERLEITISELH---IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ L + L +K+ +L ++ S K++L ++ +EL+K +E V
Sbjct: 700 DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQL-KKGLELLKASFKKTERLE-VS 757
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Y I +Q + L +E++ ++++ LEE + LE QL
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLE--SELQDLEMENQTLQKNLEELKISSKRLE-QLE 814
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
K N + S+ + KI N+EK+ L
Sbjct: 815 KENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN----VKIGNLEKENKTLS 870
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQL-ERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+ + +++ +EL+K ++L +R I+IK+ + L + + + +L
Sbjct: 871 KEIGIY----KESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKT-QQMNNDL 925
Query: 407 QRVSHELDKTREQKDALARENKKMGD 432
++++HEL+K K+ L + + D
Sbjct: 926 EKLTHELEKIGLNKERLLHDEQSTDD 951
Score = 45.6 bits (103), Expect = 4e-04
Identities = 85/423 (20%), Positives = 173/423 (40%), Gaps = 39/423 (9%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE--------GGAESQFEI 88
E+KI ++ LE Q++ +E + L +R +E G ++++E
Sbjct: 973 EEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER 1032
Query: 89 NRKRDT-ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ T ELLK++ L +E E L+ + Q + + Q+ QL E + +
Sbjct: 1033 ESQETTRELLKVKDRL----IEVERNNATLQAEKQAL----KTQLKQL-------ETQNN 1077
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
QA++ L Q ++ ++ T+ +L++ S L+ + L + + L
Sbjct: 1078 NLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLEN 1137
Query: 208 ENIELVKEVQDLKVNIENVV--YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE-ID 264
EN ++KE +DLK ++++ + K ++ + +VE D
Sbjct: 1138 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRD 1197
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK----YS- 319
LE QL ++ DLE+ L K E +K + YS
Sbjct: 1198 LEDRYNQLLKQKGQLEDLEKML-KVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQ 1256
Query: 320 --XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
L + +NN + +++RL++E L ++ + T+ +L + E L ++
Sbjct: 1257 LLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQL 1316
Query: 378 --NIEIKSR-LEETVQLYEQTQRDLRNKQTELQRVSH-ELDKTREQKDALARENKKMGDD 433
N+E ++R L + +Q R L + E + + H E + ++ + L R+ +K+ +
Sbjct: 1317 KGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1376
Query: 434 LHD 436
+ D
Sbjct: 1377 IMD 1379
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 198 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 257
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 258 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 313
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 314 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 365
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 366 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 424
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 425 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 477
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 536
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 537 QLEKTIE 543
Score = 39.5 bits (88), Expect = 0.028
Identities = 55/241 (22%), Positives = 102/241 (42%), Gaps = 29/241 (12%)
Query: 23 NIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE------ 76
N ++ ++L ++ + Q LE+E E + + L +I+ E+LE
Sbjct: 1111 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1170
Query: 77 --EAEG---------GAESQFEINRK----RDTELLKLRKLLEDVH--LESEETAHLLKK 119
E E A E+ + R +LLK + LED+ L+ E+ LL+
Sbjct: 1171 ASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLEN 1230
Query: 120 KNQEIVIDFQEQI----DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
KN E V +++ D+L T ++ KE Q + L + + N E+ +
Sbjct: 1231 KNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFS 1290
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+L+ +L I +LN ++ K L +EN L+ ++Q L ++N L+ + S
Sbjct: 1291 KLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLM--LQNRTLLEQNMES 1348
Query: 236 Q 236
+
Sbjct: 1349 K 1349
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 551 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 604
>BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein.
Length = 638
Score = 58.8 bits (136), Expect = 4e-08
Identities = 35/174 (20%), Positives = 79/174 (45%), Gaps = 1/174 (0%)
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+E + +R QLEEE+ AR R+L A ++ WR + + +
Sbjct: 1 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRR-QEEEAGALEAGEEARRRAAR 59
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
++ +E+ + RLQ E++ +DLE+ L+K+ + +++ E
Sbjct: 60 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 119
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
K+ + V+ E+ + + R ++ ++ L++ +E ++ L R+N+ + +L
Sbjct: 120 EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 173
Score = 56.8 bits (131), Expect = 2e-07
Identities = 86/465 (18%), Positives = 169/465 (36%), Gaps = 24/465 (5%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+++ LE E R+R RE Q+ + R EE G E+ E R+ E L +
Sbjct: 8 LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQR 67
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L + E+ + +++ Q+ + D ++Q + + EK++ KF + E A V
Sbjct: 68 LAE-KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 126
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+E+ ER E E + L R + + ++ L ++N L E++ L +
Sbjct: 127 AVEER-------ERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSS 179
Query: 223 IENV------VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH-QVEIDLESVRVQLEEE 275
++V + ++A Q ++E+ +++++ Q E +
Sbjct: 180 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 239
Query: 276 --------SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
E R L +QL A E R K +
Sbjct: 240 LQGRDEAGEERRRQLAKQLRDAEVERDEER-KQRTLAVAARKKLEGELEELKAQMASAGQ 298
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
+ ++ ++ Q L EVE E+ RE +KR + LE + ++ L
Sbjct: 299 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 358
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXX 447
+ + Q Q+D E+ + E+K L ++ ++L + ++N
Sbjct: 359 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 418
Query: 448 XXXXXXXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
+ +AE+GR+ E++ Q L G+
Sbjct: 419 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 463
Score = 51.2 bits (117), Expect = 8e-06
Identities = 72/386 (18%), Positives = 145/386 (37%), Gaps = 22/386 (5%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E EL E K L V V L + E G + E R++ + L+ ++ D
Sbjct: 210 ELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 268
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ A +KK + + + + Q+ + K A K+ K QA++ EL +VE +
Sbjct: 269 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 328
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I E + L ++ L + +++ Q+ E+ EV + ++ ++
Sbjct: 329 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 388
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-------SEARL 280
K Q+ + ++ + +ES+ +L E R
Sbjct: 389 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 448
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
LERQ+ + G +G + K + I V
Sbjct: 449 QLERQIQELRGRLG---EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 505
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + RL+ +++ +E+ A +L+ +QLE+ N+ +K + + E+ + +
Sbjct: 506 RAEKRLKE----VVLQVEEERRVADQLR---DQLEKGNLRVK----QLKRQLEEAEEEAS 554
Query: 401 NKQTELQRVSHELDKTREQKDALARE 426
Q +R+ EL+ E +++ RE
Sbjct: 555 RAQAGRRRLQRELEDVTESAESMNRE 580
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELL 97
++ + +L +ER + E + L Q+ +L RL E + GA ++ ++ +++L
Sbjct: 425 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 484
Query: 98 KLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + LE E + L++ K+ +E+V+ +E+ + + R + EK + V
Sbjct: 485 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE--RRVADQLRDQLEKGNLR--VK 540
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
+L Q+E +E RL+ + ++ E +NR + + + +R
Sbjct: 541 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 590
Score = 38.3 bits (85), Expect = 0.064
Identities = 46/264 (17%), Positives = 107/264 (40%), Gaps = 6/264 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
++A +LE ++ ++ + S + ++ ++ + Q+ +L +EE E F N
Sbjct: 276 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 335
Query: 90 RKRDTELLKLRKLLEDVHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ + L L E + L+ E A +++ Q+ + +++ +KA +EK +
Sbjct: 336 RESEKRLKGLE--AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQ 393
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + +L ++E ++ +L + + L ++ S +Q+L ++
Sbjct: 394 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 453
Query: 209 NIELVKEV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
EL + +D + + + + + S+ + + E L+
Sbjct: 454 IQELRGRLGEEDAGARARHKMTI-AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 512
Query: 267 SVRVQLEEESEARLDLERQLVKAN 290
V +Q+EEE L QL K N
Sbjct: 513 EVVLQVEEERRVADQLRDQLEKGN 536
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 58.8 bits (136), Expect = 4e-08
Identities = 74/407 (18%), Positives = 154/407 (37%), Gaps = 23/407 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT- 94
LE ++ ++ LE + Q E K L V + + + E G + Q E +K+
Sbjct: 133 LEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVR 192
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED + A +KK + + D + ID K + A K+ K QA++
Sbjct: 193 QVREMEAELEDER-KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMK 251
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ + ++++ + I + E + + ++ +L + K++ QE EL
Sbjct: 252 DCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 311
Query: 215 EVQDLK----VNIENVVYLKSQIA---SQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E+ + + +E L+++IA + + Q+ DL
Sbjct: 312 EIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNL 371
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
R ++ AR LERQ N E+ KY
Sbjct: 372 ERSHAQKNENARQQLERQ----NKEL----------KVKLQEMEGTVKSKYKASITALEA 417
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L +++N K++ +V L+ + ++ EQ + + +RL++
Sbjct: 418 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 477
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ E+ + + + +++ EL+ E DA+ RE + + L
Sbjct: 478 LKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 524
Score = 52.0 bits (119), Expect = 5e-06
Identities = 47/202 (23%), Positives = 92/202 (45%), Gaps = 6/202 (2%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L ++R ++ +LE ER+ R + L + + L ++ A + + RK
Sbjct: 189 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 248
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ + L+D EE K+N++ + + ++ QL + A AE+ K + Q E
Sbjct: 249 QMKDCMRELDDTRASREEIL-AQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD 307
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ N + + + RLE I++L ++EE I RL + N+++ +
Sbjct: 308 ELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI---NDRLKKANLQIDQ 364
Query: 215 EVQDLKVNIENVVYLKSQIASQ 236
DL N+E K++ A Q
Sbjct: 365 INTDL--NLERSHAQKNENARQ 384
Score = 45.6 bits (103), Expect = 4e-04
Identities = 39/188 (20%), Positives = 89/188 (47%), Gaps = 9/188 (4%)
Query: 35 RLEDKIRLIQDDLESERELRQRI--EREKADLSVQVIQLSERLE--EAEGGAESQFEINR 90
RLE +I ++++LE E+ + I +KA+L + I LE A+ ++ ++ R
Sbjct: 329 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 388
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ +KL+++ V + + + L+ K + +EQ+D TK + A K+ + +
Sbjct: 389 QNKELKVKLQEMEGTVKSKYKASITALEAK----IAQLEEQLDNETKERQAACKQVRRTE 444
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
++ ++L QV++ + ++ + +L ++EE + +++L +E +
Sbjct: 445 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE-L 503
Query: 211 ELVKEVQD 218
E E D
Sbjct: 504 EDATETAD 511
Score = 41.9 bits (94), Expect = 0.005
Identities = 28/108 (25%), Positives = 56/108 (51%), Gaps = 3/108 (2%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYE 393
++ +EK K L+ +VE + LE+ + + +LE VN++ +K++ E +Q E
Sbjct: 123 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-VNLQAMKAQFERDLQGRDE 181
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
Q++ + +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 182 QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 229
Score = 38.3 bits (85), Expect = 0.064
Identities = 54/324 (16%), Positives = 120/324 (37%), Gaps = 10/324 (3%)
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
LE+ + E L K+ E+ D D + K+ EK K + +V E+ Q+E
Sbjct: 88 LEEAMEQKAELERLNKQFRTEME-DLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 146
Query: 163 VTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ E RLE+ + + + E +L K++L ++ E+ E++D +
Sbjct: 147 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 206
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
V + ++ L +++ ++ +L++ +R +
Sbjct: 207 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREE 266
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
+ Q + ++ ++ + K +
Sbjct: 267 ILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALE 325
Query: 342 QKSRLQSEVEVLIIDLEKANGTAR----ELQKRTEQLERVNIEIKSRLEET-VQLYEQTQ 396
+K RL++ + L +LE+ G L+K Q++++N ++ LE + Q E +
Sbjct: 326 EKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL--NLERSHAQKNENAR 383
Query: 397 RDLRNKQTELQRVSHELDKTREQK 420
+ L + EL+ E++ T + K
Sbjct: 384 QQLERQNKELKVKLQEMEGTVKSK 407
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/198 (16%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 346 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV-------KLQ 398
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 399 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 457
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
+ + + + K + +L Q+E +E + + +L+ + + + +NR
Sbjct: 458 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNR-- 515
Query: 196 VDITSHKQRLSQENIELV 213
+++S K +L + ++ V
Sbjct: 516 -EVSSLKNKLRRGDLPFV 532
Score = 37.9 bits (84), Expect = 0.084
Identities = 21/91 (23%), Positives = 45/91 (49%)
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRD 398
+E+ + ++E+E L+ + + EL+K LE+ E+K++LEE + T+
Sbjct: 98 LERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDA 157
Query: 399 LRNKQTELQRVSHELDKTREQKDALARENKK 429
+ LQ + + ++ + +D + E KK
Sbjct: 158 KLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 188
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 58.0 bits (134), Expect = 7e-08
Identities = 74/433 (17%), Positives = 171/433 (39%), Gaps = 30/433 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQF 86
S RL + ++ QD L++E+ R + E DLS ++ + + L++ +
Sbjct: 287 SLTMRLHETLKQCQD-LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E + K E L+ + LE + + L++KN+ + Q ++ QL + ++ +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL----QGKLSQLEEHLSQLQDNP 401
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + EV + Q+E + +E T++ +L+ + L E + + + +
Sbjct: 402 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFE 458
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXX--ASLHQVE 262
+E +L + DL+ +I N+ K ++ ASQ A++ Q +
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 518
Query: 263 IDLESVRVQ-----------LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L ++ Q L+++ +A L Q+ + + + +
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ + A + +E + +++E+L L+ AN Q
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 372 EQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
Q +R E+ ++EE V+ Q Q + + + EL+ + +K+ +A+E
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKD 698
Query: 429 KMGDDLHDARANI 441
++ + L + ++
Sbjct: 699 QLQEQLQALKESL 711
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/427 (18%), Positives = 160/427 (37%), Gaps = 37/427 (8%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGG------AESQFEINRKRDTELLKLRK 101
+ E++L++ E+++A QL+ EE E A Q E K L++ +
Sbjct: 562 QKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ 621
Query: 102 LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV- 160
V E+ ++A + Q + ++++L A +E+ + QA+V EL Q+
Sbjct: 622 QQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 681
Query: 161 ---------ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR----LSQ 207
E V +EK + + + L+ ++ +EE R D +QR L
Sbjct: 682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Query: 208 ENIELV----KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
E LV +E ++L+ L++++ A+ H E
Sbjct: 742 ETRSLVEQHKRERKELEEERAGRKGLEARLLQLGEAHQAETEVLRRELAEAMAAQHTAES 801
Query: 264 DLESVRVQL-----------EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXX 312
+ E + ++ +EE++ + QL+ E R +
Sbjct: 802 ECEQLVKEVAAWRDGYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIES 861
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE 372
+ S L + V++++ R Q + L EK T++E+ +
Sbjct: 862 HSELQISRQQNKLAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLET 921
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
+ + + ++ E V+ E + R + ++ + T+ A+ RE ++MG+
Sbjct: 922 LVRKAGEQQETASRELVK--EPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGN 979
Query: 433 DLHDARA 439
+L RA
Sbjct: 980 ELERLRA 986
Score = 36.3 bits (80), Expect = 0.26
Identities = 73/390 (18%), Positives = 148/390 (37%), Gaps = 23/390 (5%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE 109
E L Q E +A+ V +L+E + A+ AES+ E K E+ R ED E
Sbjct: 768 EARLLQLGEAHQAETEVLRRELAEAMA-AQHTAESECEQLVK---EVAAWRDGYEDSQQE 823
Query: 110 S-------EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV-- 160
+E LK++ ++ + QE +++ ++ +E + S+ Q ++ EL A +
Sbjct: 824 EAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNKLAELHANLAR 883
Query: 161 --ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ V ++++ K + L ++ +E+ R + ++ + ELVKE
Sbjct: 884 ALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKE--P 941
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ +L+ Q Q L ++ L + Q +EE
Sbjct: 942 ARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEE--- 998
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R ER++ + E G ++ + L +
Sbjct: 999 RGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTE 1058
Query: 339 VE---KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E ++ ++L+ I +LE+ T ++L+++ + E+ + E E T
Sbjct: 1059 KEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT 1118
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALAR 425
L + E+ ++ + K +EQ D+L R
Sbjct: 1119 GPKLEALRAEVSKLEQQCQKQQEQADSLER 1148
Score = 35.5 bits (78), Expect = 0.45
Identities = 37/145 (25%), Positives = 66/145 (45%), Gaps = 9/145 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER---LEEAEGGAESQF 86
L A L + I L Q E ER +Q + EKA + Q+ L + L E G +
Sbjct: 1400 LRAQRELGELIPLRQKVAEQERTAQQ-LRAEKASYAEQLSMLKKAHGLLAEENRGLGERA 1458
Query: 87 EINRK-RDTELLKLRKL----LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ R+ + EL + R+ L V ++E ++++ Q + + + K +
Sbjct: 1459 NLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Query: 142 AEKEKSKFQAEVYELLAQVENVTKE 166
+E+ +FQ E +L AQVE ++K+
Sbjct: 1519 VLEERQRFQEERQKLTAQVEELSKK 1543
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 58.0 bits (134), Expect = 7e-08
Identities = 74/433 (17%), Positives = 171/433 (39%), Gaps = 30/433 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQF 86
S RL + ++ QD L++E+ R + E DLS ++ + + L++ +
Sbjct: 287 SLTMRLHETLKQCQD-LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E + K E L+ + LE + + L++KN+ + Q ++ QL + ++ +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL----QGKLSQLEEHLSQLQDNP 401
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + EV + Q+E + +E T++ +L+ + L E + + + +
Sbjct: 402 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFE 458
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXX--ASLHQVE 262
+E +L + DL+ +I N+ K ++ ASQ A++ Q +
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 518
Query: 263 IDLESVRVQ-----------LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L ++ Q L+++ +A L Q+ + + + +
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ + A + +E + +++E+L L+ AN Q
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 372 EQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
Q +R E+ ++EE V+ Q Q + + + EL+ + +K+ +A+E
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKD 698
Query: 429 KMGDDLHDARANI 441
++ + L + ++
Sbjct: 699 QLQEQLQALKESL 711
Score = 44.8 bits (101), Expect = 7e-04
Identities = 70/381 (18%), Positives = 144/381 (37%), Gaps = 16/381 (4%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGG------AESQFEINRKRDTELLKLRK 101
+ E++L++ E+++A QL+ EE E A Q E K L++ +
Sbjct: 562 QKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ 621
Query: 102 LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE 161
V E+ ++A + Q + ++++L A +E+ + QA+V EL Q+
Sbjct: 622 QQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 681
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ + + + +L E L T + K+R + E + + +LK
Sbjct: 682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
++V + + + HQ E E +R +L E A+
Sbjct: 742 ETRSLVE-QHKRERKELEEERAGRKGLEARLQQLGEAHQAE--TEVLRRELAEAMAAQHT 798
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL------IAK 335
E + + E+ WR ++ + L +A
Sbjct: 799 AESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAG 858
Query: 336 I-NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
I ++ E Q SR Q+E+ L +L +A +E + R ++L ++ ++ T + +
Sbjct: 859 IESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 918
Query: 395 TQRDLRNKQTELQRVSHELDK 415
+ +R + + S EL K
Sbjct: 919 LETLVRKAGEQQETASRELVK 939
Score = 40.7 bits (91), Expect = 0.012
Identities = 74/390 (18%), Positives = 150/390 (38%), Gaps = 23/390 (5%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE 109
E L+Q E +A+ V +L+E + A+ AES+ E K E+ R+ ED E
Sbjct: 768 EARLQQLGEAHQAETEVLRRELAEAMA-AQHTAESECEQLVK---EVAAWRERYEDSQQE 823
Query: 110 S-------EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV-- 160
+E LK++ ++ + QE +++ ++ +E + S+ Q E+ EL A +
Sbjct: 824 EAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLAR 883
Query: 161 --ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ V ++++ K + L ++ +E+ R + ++ + ELVKE
Sbjct: 884 ALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKE--P 941
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ +L+ Q Q L ++ L + Q +EE
Sbjct: 942 ARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEE--- 998
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R ER++ + E G ++ + L +
Sbjct: 999 RGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTE 1058
Query: 339 VE---KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E ++ ++L+ I +LE+ T ++L+++ + E+ + E E T
Sbjct: 1059 KEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT 1118
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALAR 425
L + E+ ++ + K +EQ D+L R
Sbjct: 1119 GPKLEALRAEVSKLEQQCQKQQEQADSLER 1148
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 10/180 (5%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+ + E + L Q + E+ + E E++ +RD+ L L+ LE+ E +
Sbjct: 1123 EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQ 1182
Query: 115 HLLKKKNQEI------VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTK--- 165
L +E+ V D + D+ AR +E + + + L +V + +
Sbjct: 1183 SALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVL 1242
Query: 166 EKITISKTCERLEITISELHIKIEELNRTI-VDITSHKQRLSQENIELVKEVQDLKVNIE 224
EK SK +RL + SE K+EE R + + S+ R ++ + L +EVQ L+ E
Sbjct: 1243 EKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAE 1302
Score = 35.5 bits (78), Expect = 0.45
Identities = 62/388 (15%), Positives = 152/388 (39%), Gaps = 20/388 (5%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S L ++++ ++++ E +R + + +E L+ Q + E +E + E F+ +
Sbjct: 1288 SALREEVQSLREEAEKQRVASENLRQE---LTSQAERAEELGQELKAWQEKFFQKEQALS 1344
Query: 94 T---ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
T E + L+ ++ L ++ L+ + +E+++Q + E + Q
Sbjct: 1345 TLQLEHTSTQALVSEL-LPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ 1403
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E+ EL+ + V +++ +T ++L + ++ L + + + + R E
Sbjct: 1404 RELGELIPLRQKVAEQE----RTAQQLRAEKASYAEQLSMLKKAH-GLLAEENRGLGERA 1458
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
L ++ +++++ Y++ ++A+ L + E +V
Sbjct: 1459 NLGRQFLEVELDQAREKYVQ-ELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1517
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
++ EE + R ERQ + A E F
Sbjct: 1518 KVLEERQ-RFQEERQKLTAQVE---QLEVFQREQTKQVEELSKKLADSDQASKVQQQKLK 1573
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER---VNIEIKSRLEE 387
+ A+ +++ RLQ+++ L L + A + + E+ + + L+E
Sbjct: 1574 AVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE 1633
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDK 415
++ EQ Q++ + + E +R+ HEL +
Sbjct: 1634 QLRSLEQLQKENKELRAEAERLGHELQQ 1661
Score = 33.9 bits (74), Expect = 1.4
Identities = 43/202 (21%), Positives = 85/202 (42%), Gaps = 9/202 (4%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER---LEEAEGGAESQF 86
L A L + I L Q E ER +Q + EKA + Q+ L + L E G +
Sbjct: 1400 LRAQRELGELIPLRQKVAEQERTAQQ-LRAEKASYAEQLSMLKKAHGLLAEENRGLGERA 1458
Query: 87 EINRK-RDTELLKLRKL----LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ R+ + EL + R+ L V ++E ++++ Q + + + K +
Sbjct: 1459 NLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
+E+ +FQ E +L AQVE + + +K E L +++ + + + + +
Sbjct: 1519 VLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQ 1578
Query: 202 KQRLSQENIELVKEVQDLKVNI 223
QE L ++ +L+ +
Sbjct: 1579 GGESQQEAQRLQAQLNELQAQL 1600
>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 58.0 bits (134), Expect = 7e-08
Identities = 78/416 (18%), Positives = 168/416 (40%), Gaps = 23/416 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L R + + + +L++ + L + E + L QV++L +L+ +G E E+ K
Sbjct: 410 LERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQG-PEPAKEVLLK- 467
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+LL+ R+LLE+V + L+ + +E+ +++ E + ++Q +
Sbjct: 468 --DLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRD 525
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+L +++ T++ + +++ + L ++EE + T H Q + Q+N E
Sbjct: 526 TEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEE----TGHWQSMFQKNKE- 580
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ K + + K ++ + QVE+ L+ ++
Sbjct: 581 --DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV-LKKELLRT 637
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+EE + L ERQ + G H R + + L
Sbjct: 638 QEELK-ELQAERQSQEVAGR--H-RDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQL 693
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
K K ++E VL T RE Q+ ++ R + ++ +L+ET L
Sbjct: 694 RQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLV 753
Query: 393 ---EQTQRDLRNK----QTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + LR+K + E Q++ L+ ++E++ +LA + + L +A+ +
Sbjct: 754 DGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL 809
Score = 52.0 bits (119), Expect = 5e-06
Identities = 79/405 (19%), Positives = 159/405 (39%), Gaps = 20/405 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG----AESQFEIN 89
+RL DK++ ++ + + E + E+ L+ L RLEEA+ G + Q +N
Sbjct: 761 ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 820
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKK----NQEIVIDFQEQIDQLTKTKARAEKE 145
R + E K R++L E EE LL + N+E+ ++ L + +A+ E
Sbjct: 821 RALEEE-GKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDY 879
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K K + EV + Q ++ E S RL+ I L ++ K+ L
Sbjct: 880 KEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELL 939
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
+Q L +E ++ K + ++ + + +++ +
Sbjct: 940 AQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQV 999
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ +R +L +E AR DLE + + +++ K S
Sbjct: 1000 DQLRTELMQERSARQDLECDKISLERQNKDLKTRL---------ASSEGFQKPSASLSQL 1050
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN-GTARELQKRTEQLERVNIEIKSR 384
L ++ E++K+ LQS L +++ + E Q +Q +++++ +K+
Sbjct: 1051 ESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKAL 1110
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ + E+ +R L + + QR E + EQ A + +K
Sbjct: 1111 KRQVDEAEEEIER-LDGLRKKAQREVEEQHEVNEQLQARIKSLEK 1154
Score = 45.2 bits (102), Expect = 6e-04
Identities = 42/193 (21%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LSRL+D+I+ ++ L++ + ER+ A L ++ L++RL+ E AE++ R
Sbjct: 908 LSRLQDEIQRLRQALQA-----SQAERDTARLDKEL--LAQRLQGLEQEAENKKRSQDDR 960
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + + + E +E + ++ V ++Q+DQL + + + +
Sbjct: 961 ARQLKGLEEKVSRLETELDEEKNTVELLTDR-VNRGRDQVDQLRTELMQERSARQDLECD 1019
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
L Q +++ K ++ S+ ++ ++S+L + + L + K L N +L
Sbjct: 1020 KISLERQNKDL-KTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1078
Query: 213 VKEVQDLKVNIEN 225
++V++L + IE+
Sbjct: 1079 ERKVKELSIQIED 1091
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 7/205 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
++R D++ ++ +L ER RQ +E +K L Q L RL +EG + +++
Sbjct: 992 VNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLE 1051
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L +L + E E+T +L+ N+++ +E Q+ + +K +
Sbjct: 1052 SQNQLLQERLQAE---EREKT--VLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLR 1106
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLSQENIE 211
V L QV+ +E + ++ + + E H E+L I + ++ S+ E
Sbjct: 1107 VKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAE 1166
Query: 212 LVKEVQDLKVNIE-NVVYLKSQIAS 235
+ + L + E + VY S IAS
Sbjct: 1167 SALKNEGLSSDEEFDSVYDPSSIAS 1191
Score = 36.3 bits (80), Expect = 0.26
Identities = 67/356 (18%), Positives = 143/356 (40%), Gaps = 41/356 (11%)
Query: 70 QLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQ 129
+L+ ++EE + + + + +K + + L + LE+ E LL+++ E
Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQ-QSN 421
Query: 130 EQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+++ + + + E + + +V EL ++++V + E+ + +L ++
Sbjct: 422 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPE-------PAKEVLLKDL-LETR 473
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
EL + ++ KQR+ ++ +E+ LK LK ++AS+
Sbjct: 474 EL---LEEVLEGKQRVEEQLRLRERELTALKGA------LKEEVASRDQEVEHVRQQYQR 524
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
S+ D + + ++ S L+R+L + + E GHW+S F
Sbjct: 525 DTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMF--------- 575
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN---GTARE 366
L+ E+ + L ++EVL +LE+A G R+
Sbjct: 576 ---------QKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQ 626
Query: 367 LQKRTEQLERVNIEIKS-RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
++ ++L R E+K + E Q RD R + +L + E D+ RE ++
Sbjct: 627 VEVLKKELLRTQEELKELQAERQSQEVAGRHRD-RELEKQLAVLRVEADRGRELEE 681
Score = 32.3 bits (70), Expect = 4.2
Identities = 74/410 (18%), Positives = 152/410 (37%), Gaps = 25/410 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE++ +Q L+ R+ + + K + L +R E E N +
Sbjct: 679 LEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR 738
Query: 96 LLKLRKLLEDVH--LESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + L++ ++ E L+ K Q + + Q QL + +++E+ A
Sbjct: 739 ILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQ----QLEEALNASQEEEGSLAAA 794
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE---- 208
L A++E + + + + L + E + E L R ++ K+ L +
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 854
Query: 209 NIELVKEVQDLKVNIENVVY----LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
N EL K +D K ++ + K + + L +++ +
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 914
Query: 265 LESVRVQLE----EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
++ +R L+ E ARLD E + G +K K S
Sbjct: 915 IQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENK-KRSQDDRARQLKGLEEKVSR 973
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
T+ + V +R + +V+ L +L + ++L+ LER N +
Sbjct: 974 LETELDEEKNTVELLTDRV----NRGRDQVDQLRTELMQERSARQDLECDKISLERQNKD 1029
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+K+RL + + +++ L +++ Q + L +K L N+K+
Sbjct: 1030 LKTRLASS-EGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1078
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 58.0 bits (134), Expect = 7e-08
Identities = 78/416 (18%), Positives = 168/416 (40%), Gaps = 23/416 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L R + + + +L++ + L + E + L QV++L +L+ +G E E+ K
Sbjct: 410 LERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQG-PEPAKEVLLK- 467
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+LL+ R+LLE+V + L+ + +E+ +++ E + ++Q +
Sbjct: 468 --DLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRD 525
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+L +++ T++ + +++ + L ++EE + T H Q + Q+N E
Sbjct: 526 TEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEE----TGHWQSMFQKNKE- 580
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ K + + K ++ + QVE+ L+ ++
Sbjct: 581 --DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV-LKKELLRT 637
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+EE + L ERQ + G H R + + L
Sbjct: 638 QEELK-ELQAERQSQEVAGR--H-RDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQL 693
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
K K ++E VL T RE Q+ ++ R + ++ +L+ET L
Sbjct: 694 RQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLV 753
Query: 393 ---EQTQRDLRNK----QTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + LR+K + E Q++ L+ ++E++ +LA + + L +A+ +
Sbjct: 754 DGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL 809
Score = 52.0 bits (119), Expect = 5e-06
Identities = 79/405 (19%), Positives = 159/405 (39%), Gaps = 20/405 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG----AESQFEIN 89
+RL DK++ ++ + + E + E+ L+ L RLEEA+ G + Q +N
Sbjct: 761 ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 820
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKK----NQEIVIDFQEQIDQLTKTKARAEKE 145
R + E K R++L E EE LL + N+E+ ++ L + +A+ E
Sbjct: 821 RALEEE-GKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDY 879
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K K + EV + Q ++ E S RL+ I L ++ K+ L
Sbjct: 880 KEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELL 939
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
+Q L +E ++ K + ++ + + +++ +
Sbjct: 940 AQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQV 999
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ +R +L +E AR DLE + + +++ K S
Sbjct: 1000 DQLRTELMQERSARQDLECDKISLERQNKDLKTRL---------ASSEGFQKPSASLSQL 1050
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN-GTARELQKRTEQLERVNIEIKSR 384
L ++ E++K+ LQS L +++ + E Q +Q +++++ +K+
Sbjct: 1051 ESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKAL 1110
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ + E+ +R L + + QR E + EQ A + +K
Sbjct: 1111 KRQVDEAEEEIER-LDGLRKKAQREVEEQHEVNEQLQARIKSLEK 1154
Score = 45.2 bits (102), Expect = 6e-04
Identities = 42/193 (21%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LSRL+D+I+ ++ L++ + ER+ A L ++ L++RL+ E AE++ R
Sbjct: 908 LSRLQDEIQRLRQALQA-----SQAERDTARLDKEL--LAQRLQGLEQEAENKKRSQDDR 960
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + + + E +E + ++ V ++Q+DQL + + + +
Sbjct: 961 ARQLKGLEEKVSRLETELDEEKNTVELLTDR-VNRGRDQVDQLRTELMQERSARQDLECD 1019
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
L Q +++ K ++ S+ ++ ++S+L + + L + K L N +L
Sbjct: 1020 KISLERQNKDL-KTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1078
Query: 213 VKEVQDLKVNIEN 225
++V++L + IE+
Sbjct: 1079 ERKVKELSIQIED 1091
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 7/205 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
++R D++ ++ +L ER RQ +E +K L Q L RL +EG + +++
Sbjct: 992 VNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLE 1051
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L +L + E E+T +L+ N+++ +E Q+ + +K +
Sbjct: 1052 SQNQLLQERLQAE---EREKT--VLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLR 1106
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLSQENIE 211
V L QV+ +E + ++ + + E H E+L I + ++ S+ E
Sbjct: 1107 VKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAE 1166
Query: 212 LVKEVQDLKVNIE-NVVYLKSQIAS 235
+ + L + E + VY S IAS
Sbjct: 1167 SALKNEGLSSDEEFDSVYDPSSIAS 1191
Score = 36.3 bits (80), Expect = 0.26
Identities = 67/356 (18%), Positives = 143/356 (40%), Gaps = 41/356 (11%)
Query: 70 QLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQ 129
+L+ ++EE + + + + +K + + L + LE+ E LL+++ E
Sbjct: 363 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQ-QSN 421
Query: 130 EQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+++ + + + E + + +V EL ++++V + E+ + +L ++
Sbjct: 422 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPE-------PAKEVLLKDL-LETR 473
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
EL + ++ KQR+ ++ +E+ LK LK ++AS+
Sbjct: 474 EL---LEEVLEGKQRVEEQLRLRERELTALKGA------LKEEVASRDQEVEHVRQQYQR 524
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
S+ D + + ++ S L+R+L + + E GHW+S F
Sbjct: 525 DTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMF--------- 575
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN---GTARE 366
L+ E+ + L ++EVL +LE+A G R+
Sbjct: 576 ---------QKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQ 626
Query: 367 LQKRTEQLERVNIEIKS-RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
++ ++L R E+K + E Q RD R + +L + E D+ RE ++
Sbjct: 627 VEVLKKELLRTQEELKELQAERQSQEVAGRHRD-RELEKQLAVLRVEADRGRELEE 681
Score = 32.3 bits (70), Expect = 4.2
Identities = 74/410 (18%), Positives = 152/410 (37%), Gaps = 25/410 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE++ +Q L+ R+ + + K + L +R E E N +
Sbjct: 679 LEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR 738
Query: 96 LLKLRKLLEDVH--LESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + L++ ++ E L+ K Q + + Q QL + +++E+ A
Sbjct: 739 ILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQ----QLEEALNASQEEEGSLAAA 794
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE---- 208
L A++E + + + + L + E + E L R ++ K+ L +
Sbjct: 795 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 854
Query: 209 NIELVKEVQDLKVNIENVVY----LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
N EL K +D K ++ + K + + L +++ +
Sbjct: 855 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 914
Query: 265 LESVRVQLE----EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
++ +R L+ E ARLD E + G +K K S
Sbjct: 915 IQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENK-KRSQDDRARQLKGLEEKVSR 973
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
T+ + V +R + +V+ L +L + ++L+ LER N +
Sbjct: 974 LETELDEEKNTVELLTDRV----NRGRDQVDQLRTELMQERSARQDLECDKISLERQNKD 1029
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+K+RL + + +++ L +++ Q + L +K L N+K+
Sbjct: 1030 LKTRLASS-EGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1078
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 58.0 bits (134), Expect = 7e-08
Identities = 74/433 (17%), Positives = 171/433 (39%), Gaps = 30/433 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQF 86
S RL + ++ QD L++E+ R + E DLS ++ + + L++ +
Sbjct: 293 SLTMRLHETLKQCQD-LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 351
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E + K E L+ + LE + + L++KN+ + Q ++ QL + ++ +
Sbjct: 352 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL----QGKLSQLEEHLSQLQDNP 407
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + EV + Q+E + +E T++ +L+ + L E + + + +
Sbjct: 408 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFE 464
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXX--ASLHQVE 262
+E +L + DL+ +I N+ K ++ ASQ A++ Q +
Sbjct: 465 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 524
Query: 263 IDLESVRVQ-----------LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L ++ Q L+++ +A L Q+ + + + +
Sbjct: 525 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 584
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ + A + +E + +++E+L L+ AN Q
Sbjct: 585 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 644
Query: 372 EQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
Q +R E+ ++EE V+ Q Q + + + EL+ + +K+ +A+E
Sbjct: 645 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKD 704
Query: 429 KMGDDLHDARANI 441
++ + L + ++
Sbjct: 705 QLQEQLQALKESL 717
Score = 44.8 bits (101), Expect = 7e-04
Identities = 70/381 (18%), Positives = 144/381 (37%), Gaps = 16/381 (4%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGG------AESQFEINRKRDTELLKLRK 101
+ E++L++ E+++A QL+ EE E A Q E K L++ +
Sbjct: 568 QKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ 627
Query: 102 LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE 161
V E+ ++A + Q + ++++L A +E+ + QA+V EL Q+
Sbjct: 628 QQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 687
Query: 162 NVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
+ ++ + + + +L E L T + K+R + E + + +LK
Sbjct: 688 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 747
Query: 222 NIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLD 281
++V + + + HQ E E +R +L E A+
Sbjct: 748 ETRSLVE-QHKRERKELEEERAGRKGLEARLQQLGEAHQAE--TEVLRRELAEAMAAQHT 804
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL------IAK 335
E + + E+ WR ++ + L +A
Sbjct: 805 AESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAG 864
Query: 336 I-NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
I ++ E Q SR Q+E+ L +L +A +E + R ++L ++ ++ T + +
Sbjct: 865 IESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 924
Query: 395 TQRDLRNKQTELQRVSHELDK 415
+ +R + + S EL K
Sbjct: 925 LETLVRKAGEQQETASRELVK 945
Score = 40.7 bits (91), Expect = 0.012
Identities = 74/390 (18%), Positives = 150/390 (38%), Gaps = 23/390 (5%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE 109
E L+Q E +A+ V +L+E + A+ AES+ E K E+ R+ ED E
Sbjct: 774 EARLQQLGEAHQAETEVLRRELAEAMA-AQHTAESECEQLVK---EVAAWRERYEDSQQE 829
Query: 110 S-------EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV-- 160
+E LK++ ++ + QE +++ ++ +E + S+ Q E+ EL A +
Sbjct: 830 EAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLAR 889
Query: 161 --ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ V ++++ K + L ++ +E+ R + ++ + ELVKE
Sbjct: 890 ALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKE--P 947
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+ +L+ Q Q L ++ L + Q +EE
Sbjct: 948 ARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEE--- 1004
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
R ER++ + E G ++ + L +
Sbjct: 1005 RGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTE 1064
Query: 339 VE---KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
E ++ ++L+ I +LE+ T ++L+++ + E+ + E E T
Sbjct: 1065 KEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT 1124
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALAR 425
L + E+ ++ + K +EQ D+L R
Sbjct: 1125 GPKLEALRAEVSKLEQQCQKQQEQADSLER 1154
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/180 (23%), Positives = 78/180 (43%), Gaps = 10/180 (5%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+ + E + L Q + E+ + E E++ +RD+ L L+ LE+ E +
Sbjct: 1129 EALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQ 1188
Query: 115 HLLKKKNQEI------VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTK--- 165
L +E+ V D + D+ AR +E + + + L +V + +
Sbjct: 1189 SALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVL 1248
Query: 166 EKITISKTCERLEITISELHIKIEELNRTI-VDITSHKQRLSQENIELVKEVQDLKVNIE 224
EK SK +RL + SE K+EE R + + S+ R ++ + L +EVQ L+ E
Sbjct: 1249 EKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAE 1308
Score = 35.5 bits (78), Expect = 0.45
Identities = 62/388 (15%), Positives = 152/388 (39%), Gaps = 20/388 (5%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
S L ++++ ++++ E +R + + +E L+ Q + E +E + E F+ +
Sbjct: 1294 SALREEVQSLREEAEKQRVASENLRQE---LTSQAERAEELGQELKAWQEKFFQKEQALS 1350
Query: 94 T---ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
T E + L+ ++ L ++ L+ + +E+++Q + E + Q
Sbjct: 1351 TLQLEHTSTQALVSEL-LPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ 1409
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E+ EL+ + V +++ +T ++L + ++ L + + + + R E
Sbjct: 1410 RELGELIPLRQKVAEQE----RTAQQLRAEKASYAEQLSMLKKAH-GLLAEENRGLGERA 1464
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
L ++ +++++ Y++ ++A+ L + E +V
Sbjct: 1465 NLGRQFLEVELDQAREKYVQ-ELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1523
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
++ EE + R ERQ + A E F
Sbjct: 1524 KVLEERQ-RFQEERQKLTAQVE---QLEVFQREQTKQVEELSKKLADSDQASKVQQQKLK 1579
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER---VNIEIKSRLEE 387
+ A+ +++ RLQ+++ L L + A + + E+ + + L+E
Sbjct: 1580 AVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQE 1639
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDK 415
++ EQ Q++ + + E +R+ HEL +
Sbjct: 1640 QLRSLEQLQKENKELRAEAERLGHELQQ 1667
Score = 33.9 bits (74), Expect = 1.4
Identities = 43/202 (21%), Positives = 85/202 (42%), Gaps = 9/202 (4%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER---LEEAEGGAESQF 86
L A L + I L Q E ER +Q + EKA + Q+ L + L E G +
Sbjct: 1406 LRAQRELGELIPLRQKVAEQERTAQQ-LRAEKASYAEQLSMLKKAHGLLAEENRGLGERA 1464
Query: 87 EINRK-RDTELLKLRKL----LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ R+ + EL + R+ L V ++E ++++ Q + + + K +
Sbjct: 1465 NLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1524
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
+E+ +FQ E +L AQVE + + +K E L +++ + + + + +
Sbjct: 1525 VLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQ 1584
Query: 202 KQRLSQENIELVKEVQDLKVNI 223
QE L ++ +L+ +
Sbjct: 1585 GGESQQEAQRLQAQLNELQAQL 1606
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 58.0 bits (134), Expect = 7e-08
Identities = 78/416 (18%), Positives = 168/416 (40%), Gaps = 23/416 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L R + + + +L++ + L + E + L QV++L +L+ +G E E+ K
Sbjct: 415 LERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQG-PEPAKEVLLK- 472
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+LL+ R+LLE+V + L+ + +E+ +++ E + ++Q +
Sbjct: 473 --DLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQRD 530
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+L +++ T++ + +++ + L ++EE + T H Q + Q+N E
Sbjct: 531 TEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEE----TGHWQSMFQKNKE- 585
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
+++ K + + K ++ + QVE+ L+ ++
Sbjct: 586 --DLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEV-LKKELLRT 642
Query: 273 EEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTL 332
+EE + L ERQ + G H R + + L
Sbjct: 643 QEELK-ELQAERQSQEVAGR--H-RDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQL 698
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
K K ++E VL T RE Q+ ++ R + ++ +L+ET L
Sbjct: 699 RQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLV 758
Query: 393 ---EQTQRDLRNK----QTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E + LR+K + E Q++ L+ ++E++ +LA + + L +A+ +
Sbjct: 759 DGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL 814
Score = 52.0 bits (119), Expect = 5e-06
Identities = 79/405 (19%), Positives = 159/405 (39%), Gaps = 20/405 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG----AESQFEIN 89
+RL DK++ ++ + + E + E+ L+ L RLEEA+ G + Q +N
Sbjct: 766 ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 825
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKK----NQEIVIDFQEQIDQLTKTKARAEKE 145
R + E K R++L E EE LL + N+E+ ++ L + +A+ E
Sbjct: 826 RALEEE-GKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDY 884
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K K + EV + Q ++ E S RL+ I L ++ K+ L
Sbjct: 885 KEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELL 944
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
+Q L +E ++ K + ++ + + +++ +
Sbjct: 945 AQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQV 1004
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ +R +L +E AR DLE + + +++ K S
Sbjct: 1005 DQLRTELMQERSARQDLECDKISLERQNKDLKTRL---------ASSEGFQKPSASLSQL 1055
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN-GTARELQKRTEQLERVNIEIKSR 384
L ++ E++K+ LQS L +++ + E Q +Q +++++ +K+
Sbjct: 1056 ESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKAL 1115
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ + E+ +R L + + QR E + EQ A + +K
Sbjct: 1116 KRQVDEAEEEIER-LDGLRKKAQREVEEQHEVNEQLQARIKSLEK 1159
Score = 45.2 bits (102), Expect = 6e-04
Identities = 42/193 (21%), Positives = 94/193 (48%), Gaps = 9/193 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LSRL+D+I+ ++ L++ + ER+ A L ++ L++RL+ E AE++ R
Sbjct: 913 LSRLQDEIQRLRQALQA-----SQAERDTARLDKEL--LAQRLQGLEQEAENKKRSQDDR 965
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + + + E +E + ++ V ++Q+DQL + + + +
Sbjct: 966 ARQLKGLEEKVSRLETELDEEKNTVELLTDR-VNRGRDQVDQLRTELMQERSARQDLECD 1024
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
L Q +++ K ++ S+ ++ ++S+L + + L + K L N +L
Sbjct: 1025 KISLERQNKDL-KTRLASSEGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1083
Query: 213 VKEVQDLKVNIEN 225
++V++L + IE+
Sbjct: 1084 ERKVKELSIQIED 1096
Score = 44.4 bits (100), Expect = 0.001
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 7/205 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
++R D++ ++ +L ER RQ +E +K L Q L RL +EG + +++
Sbjct: 997 VNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLE 1056
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L +L + E E+T +L+ N+++ +E Q+ + +K +
Sbjct: 1057 SQNQLLQERLQAE---EREKT--VLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLR 1111
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK-QRLSQENIE 211
V L QV+ +E + ++ + + E H E+L I + ++ S+ E
Sbjct: 1112 VKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKASRSAAE 1171
Query: 212 LVKEVQDLKVNIE-NVVYLKSQIAS 235
+ + L + E + VY S IAS
Sbjct: 1172 SALKNEGLSSDEEFDSVYDPSSIAS 1196
Score = 36.3 bits (80), Expect = 0.26
Identities = 67/356 (18%), Positives = 143/356 (40%), Gaps = 41/356 (11%)
Query: 70 QLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQ 129
+L+ ++EE + + + + +K + + L + LE+ E LL+++ E
Sbjct: 368 ELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQ-QSN 426
Query: 130 EQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+++ + + + E + + +V EL ++++V + E+ + +L ++
Sbjct: 427 KELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPE-------PAKEVLLKDL-LETR 478
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
EL + ++ KQR+ ++ +E+ LK LK ++AS+
Sbjct: 479 EL---LEEVLEGKQRVEEQLRLRERELTALKGA------LKEEVASRDQEVEHVRQQYQR 529
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
S+ D + + ++ S L+R+L + + E GHW+S F
Sbjct: 530 DTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMF--------- 580
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN---GTARE 366
L+ E+ + L ++EVL +LE+A G R+
Sbjct: 581 ---------QKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQ 631
Query: 367 LQKRTEQLERVNIEIKS-RLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKD 421
++ ++L R E+K + E Q RD R + +L + E D+ RE ++
Sbjct: 632 VEVLKKELLRTQEELKELQAERQSQEVAGRHRD-RELEKQLAVLRVEADRGRELEE 686
Score = 32.3 bits (70), Expect = 4.2
Identities = 74/410 (18%), Positives = 152/410 (37%), Gaps = 25/410 (6%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE++ +Q L+ R+ + + K + L +R E E N +
Sbjct: 684 LEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRR 743
Query: 96 LLKLRKLLEDVH--LESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+L L + L++ ++ E L+ K Q + + Q QL + +++E+ A
Sbjct: 744 ILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQ----QLEEALNASQEEEGSLAAA 799
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE---- 208
L A++E + + + + L + E + E L R ++ K+ L +
Sbjct: 800 KRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRL 859
Query: 209 NIELVKEVQDLKVNIENVVY----LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
N EL K +D K ++ + K + + L +++ +
Sbjct: 860 NKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDE 919
Query: 265 LESVRVQLE----EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
++ +R L+ E ARLD E + G +K K S
Sbjct: 920 IQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENK-KRSQDDRARQLKGLEEKVSR 978
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
T+ + V +R + +V+ L +L + ++L+ LER N +
Sbjct: 979 LETELDEEKNTVELLTDRV----NRGRDQVDQLRTELMQERSARQDLECDKISLERQNKD 1034
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+K+RL + + +++ L +++ Q + L +K L N+K+
Sbjct: 1035 LKTRLASS-EGFQKPSASLSQLESQNQLLQERLQAEEREKTVLQSTNRKL 1083
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 57.6 bits (133), Expect = 1e-07
Identities = 94/434 (21%), Positives = 181/434 (41%), Gaps = 47/434 (10%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESER-ELRQRIER 59
M K K S TD+N++ +S LS E I ++ + E+ EL +++
Sbjct: 1358 MKEELKEKKVEISSLSKQLTDLNVQLQNSIS-LSEKEAAISSLRKQYDEEKCELLDQVQ- 1415
Query: 60 EKADLSVQVIQLSER----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
DLS +V LS+ LE+ + + E +K + + + ++++ ++ E +
Sbjct: 1416 ---DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSK 1472
Query: 116 LLKKKNQEIVIDFQEQIDQLTKT----KARAEKEKSKFQAEVYELLAQVENVTKEKITIS 171
+K+++I + +E++DQ K K E +KSK + + L ++++ T + +
Sbjct: 1473 EAYEKDEQINL-LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1531
Query: 172 KTCERLEITISELHIKIEELN-------RTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ I I L+ ++ N + +V H Q L +E VKE ++ + +E
Sbjct: 1532 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591
Query: 225 NVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL-DL 282
N VY +K+++ ++ S+ E +L+++ +LE ES A+L +L
Sbjct: 1592 NQVYSMKAELETK-----------KKELEHVNLSVKSKEEELKALEDRLESESAAKLAEL 1640
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
+R KA +I + + + + + EK
Sbjct: 1641 KR---KAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILE--EKL 1695
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
KS S+ E LI+ N A Q+ + V + EE + + QR+L K
Sbjct: 1696 KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV----QKTYEEKISV---LQRNLTEK 1748
Query: 403 QTELQRVSHELDKT 416
+ LQRV E ++T
Sbjct: 1749 EKLLQRVGQEKEET 1762
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/396 (18%), Positives = 161/396 (40%), Gaps = 22/396 (5%)
Query: 32 ALSRLEDKIRLIQDDLESERELR-QRIE-REKADLSVQVIQLSERLEEAEGGAESQFEIN 89
AL + + + I + E + L + +E ++KA L+ +L + +EAE E+
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELE 573
Query: 90 RKRDTELLKLRKLLED--VHLESEETAH-----LLKKKNQEIVIDFQEQIDQLTKTKARA 142
+ L + + +D VHLE+E+ H ++ +K++ + + Q D L K +
Sbjct: 574 SSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 633
Query: 143 EKEKSKFQAEVYELLAQVENVT----KEKITISKTCERLEITISELHIK---IEELNRTI 195
K++ + + E + E T KE I + E E T+ +L +K +E L+ +
Sbjct: 634 LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 693
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ + +L +E L + +K +E + + Q
Sbjct: 694 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA 753
Query: 256 AS--LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++Q+E+ L+ L+E +LE + ++ GE+ +K
Sbjct: 754 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 813
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
Y L + + KQ + ++++ + + +L+ ++L +Q
Sbjct: 814 TKA-YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM---QQ 869
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LE+ N E++ +++ Q+YE D +Q + +++
Sbjct: 870 LEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/407 (20%), Positives = 177/407 (43%), Gaps = 41/407 (10%)
Query: 46 DLESERELRQR----IEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELL 97
DLE+ER L + +E +K D+ ++ IQ+ + +++ E S+ E K T++
Sbjct: 830 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK-QNSEMEQKVKSLTQVY 888
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE----QIDQLTKTKARAEKEKSKFQAEV 153
+ + LED + E E+T +L +K + +++ +E +I+ LT+ K A+++ E
Sbjct: 889 ESK--LEDGNKEQEQTKQILVEK-ENMILQMREGQKKEIEILTQ-KLSAKEDSIHILNEE 944
Query: 154 YE--LLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENI 210
YE Q + + K K + E L+ + + K++ EL T ++++ Q+ Q N
Sbjct: 945 YETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS---QKEKQFNA 1001
Query: 211 ELVKEVQDLKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXX-XASLHQVEIDLESV 268
++++ Q I + V L++ Q L+Q +L+ +
Sbjct: 1002 KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI 1061
Query: 269 R-VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+QL+E+ + +L+++++ E + K
Sbjct: 1062 HEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV--------KQDTTLNELQE 1113
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
A +N++ + +++L++ +E L +DL K+ LQ EQL +E+K EE
Sbjct: 1114 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ---EQL----VELKMLAEE 1166
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + L+ E Q + +K+ + + + E KK+ ++L
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1213
Score = 46.8 bits (106), Expect = 2e-04
Identities = 81/422 (19%), Positives = 171/422 (40%), Gaps = 23/422 (5%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIERE--KADLSVQVIQLSERLEEAEGGAESQ 85
++ +A LE + Q E+ R+L+ ++ + + + + ++S + E + E
Sbjct: 408 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 467
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + ++ KL+KL E E+ L KK Q +FQEQ+ ++ K+++E
Sbjct: 468 DVMKKSSEEQIAKLQKLHEKELARKEQE---LTKKLQTREREFQEQM-KVALEKSQSEYL 523
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K + E E LA E ++K ++++ +L +L + E I+++ S ++
Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLR----DLQQEAETYRTRILELESSLEKS 579
Query: 206 SQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
QEN K++ + + N N + Q +
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRS------KFXXXXXXXXXXXXXXXX 316
++E +R + E+E E L + + +A+ E + ++ K
Sbjct: 640 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 699
Query: 317 KYSXXXXXXXXXXXTLIAKIN---NVEKQKSRLQSEVEVLIIDLEKA-NGTARELQKRTE 372
++ T K +++QK+ Q +V+ +I + E + T + L+ +
Sbjct: 700 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 759
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
QLE + E L+E E + D++ + ELQ+ S +LD + + A + K +
Sbjct: 760 QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 819
Query: 433 DL 434
L
Sbjct: 820 QL 821
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/399 (18%), Positives = 162/399 (40%), Gaps = 48/399 (12%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLES---ERELRQR----IEREKADLSVQVIQLSER 74
+NI + L E++I+ ++ D+ES E+E Q+ ++ ++ + QL +
Sbjct: 1288 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
L E E +++ E+ L K L D++++ + + L +K + + ++Q D+
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEK--EAAISSLRKQYDE 1405
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
EK + +V +L +V+ ++KEKI+ + + SE K +
Sbjct: 1406 ----------EKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS---- 1451
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
T H+ + + I+L + ++ E + LK ++ Q
Sbjct: 1452 --RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQ----NKRFDCLKGEMEDD 1505
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ + + E +LE+ +L+ ++ ++LE + + EI
Sbjct: 1506 KSKMEKKESNLET---ELKSQTARIMELEDHITQKTIEI---------------ESLNEV 1547
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE-KANGTARELQKRTEQ 373
Y+ + + ++K E E I+ LE + EL+ + ++
Sbjct: 1548 LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE 1607
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHE 412
LE VN+ +KS+ EE L ++ + + K EL+R + +
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ 1646
Score = 46.0 bits (104), Expect = 3e-04
Identities = 88/432 (20%), Positives = 170/432 (39%), Gaps = 39/432 (9%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ R E+ ++ ++ ++S +E + EK L Q L ERL+E E + K
Sbjct: 288 VKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQ---LDERLQELEKIKDLHMAEKTKL 344
Query: 93 DTELLKLRKLLED-------VHLESEETAHLLKKKNQEIVIDFQEQIDQLTK--TKARAE 143
T+L + L+E V E++ H + +E + + +I Q+T + R +
Sbjct: 345 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ 404
Query: 144 KEKSKFQA--EVYELLAQVENV----TKEKITISKTCERLEITISELHIKI-EELNRTIV 196
KEKS+ A E+ + L+ + K K + + + +E T E I + +EL+R
Sbjct: 405 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQ 464
Query: 197 DITSHKQRLSQENI---------ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
++ ++ S+E I EL ++ Q+L ++ +
Sbjct: 465 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 524
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
SL E++L+ + E E++ R DL+++ I S
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKSLQEN 583
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAK----INNVEKQKSRLQSE-VEVLIIDLEKANG 362
++ K + +++ Q+ L +E ++VL +
Sbjct: 584 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 643
Query: 363 TAREL--QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
RE Q++ L+ I ++ +EE + E+T L KQTEL+ +S EL + + +
Sbjct: 644 KLREKCEQEKETLLKDKEIIFQAHIEE---MNEKTLEKLDVKQTELESLSSELSEVLKAR 700
Query: 421 DALARENKKMGD 432
L E + D
Sbjct: 701 HKLEEELSVLKD 712
Score = 45.2 bits (102), Expect = 6e-04
Identities = 64/362 (17%), Positives = 143/362 (39%), Gaps = 24/362 (6%)
Query: 98 KLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LR+L E+ +++ ++ H L++K +I + I+ L K +KE Q
Sbjct: 1277 QLRQLTEEQNTLNISFQQATHQLEEKENQIK-SMKADIESLVTEKEALQKEGGNQQQAAS 1335
Query: 155 ELLAQVENVTKE------KITISKT-CERLEITISELHIKIEELNRTIVD---------- 197
E + + + KE +T+ K + ++ IS L ++ +LN + +
Sbjct: 1336 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAA 1395
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
I+S +++ +E EL+ +VQDL ++ + K Q
Sbjct: 1396 ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQ 1455
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
HQ + + +++QLE +S+ + + Q+ E+ +F K
Sbjct: 1456 -HQNTV--KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKK 1512
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S ++ +++ ++ ++S EVL ++ + +EL ++ + + +
Sbjct: 1513 ESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQEL 1572
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
E +R++E + + + + + EL+ EL+ + E K + D L
Sbjct: 1573 GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1632
Query: 438 RA 439
A
Sbjct: 1633 SA 1634
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 29 DLSALSRLEDKIRLIQDDLESER-----ELRQRIEREKADLSVQVI-QLSERLEEAEGGA 82
+LS S+ E++++ ++D LESE EL+++ E++ A + Q++ Q+ E+ E+ + G
Sbjct: 1612 NLSVKSK-EEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGT 1670
Query: 83 ESQF-EINRK---RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
ES E+N K R+ E+ L + L+ V ET + + QE+ D
Sbjct: 1671 ESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV 1730
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+ E++ S Q + E ++ V +EK + + E IK+E
Sbjct: 1731 QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLE 1781
Score = 35.9 bits (79), Expect = 0.34
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 26/200 (13%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQ----VIQLSERLEEAEGGAESQFEINRKR 92
+ ++ +++ + + ERE ++I++E+ DL ++ + QL E + E+ K
Sbjct: 1961 QQELEILKKEYDQERE--EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK- 2017
Query: 93 DTELLKLRKLLEDVHLES--EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK----EK 146
E + + +E LES EET LLKK E+ D L +T R E+ +
Sbjct: 2018 --ETINKAQEVEAELLESHQEETNQLLKK--------IAEKDDDLKRTAKRYEEILDARE 2067
Query: 147 SKFQAEVYELLAQVENVTK---EKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ A+V +L Q+E + K +K+ + +TI EL ++ + I D +Q
Sbjct: 2068 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2127
Query: 204 RLSQENIELVKEVQDLKVNI 223
++ L ++ + N+
Sbjct: 2128 EFREQIHNLEDRLKKYEKNV 2147
Score = 33.5 bits (73), Expect = 1.8
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 35 RLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
RL+ +R+++ + + E E L++ ++E+ + ++ Q E LE Q + R+ +
Sbjct: 1948 RLQKDLRMLRKEHQQELEILKKEYDQEREE---KIKQEQEDLELKHNSTLKQ--LMREFN 2002
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
T+L + + LE + +ET + ++ E++ QE+ +QL K A + + +
Sbjct: 2003 TQLAQKEQELE---MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRY 2059
Query: 154 YELL-AQVENVTKEKITISKTCERLE 178
E+L A+ E +T + + E L+
Sbjct: 2060 EEILDAREEEMTAKVRDLQTQLEELQ 2085
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 57.6 bits (133), Expect = 1e-07
Identities = 94/434 (21%), Positives = 181/434 (41%), Gaps = 47/434 (10%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESER-ELRQRIER 59
M K K S TD+N++ +S LS E I ++ + E+ EL +++
Sbjct: 1358 MKEELKEKKVEISSLSKQLTDLNVQLQNSIS-LSEKEAAISSLRKQYDEEKCELLDQVQ- 1415
Query: 60 EKADLSVQVIQLSER----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
DLS +V LS+ LE+ + + E +K + + + ++++ ++ E +
Sbjct: 1416 ---DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSK 1472
Query: 116 LLKKKNQEIVIDFQEQIDQLTKT----KARAEKEKSKFQAEVYELLAQVENVTKEKITIS 171
+K+++I + +E++DQ K K E +KSK + + L ++++ T + +
Sbjct: 1473 EAYEKDEQINL-LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1531
Query: 172 KTCERLEITISELHIKIEELN-------RTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ I I L+ ++ N + +V H Q L +E VKE ++ + +E
Sbjct: 1532 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1591
Query: 225 NVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL-DL 282
N VY +K+++ ++ S+ E +L+++ +LE ES A+L +L
Sbjct: 1592 NQVYSMKAELETK-----------KKELEHVNLSVKSKEEELKALEDRLESESAAKLAEL 1640
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
+R KA +I + + + + + EK
Sbjct: 1641 KR---KAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILE--EKL 1695
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
KS S+ E LI+ N A Q+ + V + EE + + QR+L K
Sbjct: 1696 KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV----QKTYEEKISV---LQRNLTEK 1748
Query: 403 QTELQRVSHELDKT 416
+ LQRV E ++T
Sbjct: 1749 EKLLQRVGQEKEET 1762
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/396 (18%), Positives = 161/396 (40%), Gaps = 22/396 (5%)
Query: 32 ALSRLEDKIRLIQDDLESERELR-QRIE-REKADLSVQVIQLSERLEEAEGGAESQFEIN 89
AL + + + I + E + L + +E ++KA L+ +L + +EAE E+
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELE 573
Query: 90 RKRDTELLKLRKLLED--VHLESEETAH-----LLKKKNQEIVIDFQEQIDQLTKTKARA 142
+ L + + +D VHLE+E+ H ++ +K++ + + Q D L K +
Sbjct: 574 SSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 633
Query: 143 EKEKSKFQAEVYELLAQVENVT----KEKITISKTCERLEITISELHIK---IEELNRTI 195
K++ + + E + E T KE I + E E T+ +L +K +E L+ +
Sbjct: 634 LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 693
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ + +L +E L + +K +E + + Q
Sbjct: 694 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA 753
Query: 256 AS--LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++Q+E+ L+ L+E +LE + ++ GE+ +K
Sbjct: 754 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 813
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
Y L + + KQ + ++++ + + +L+ ++L +Q
Sbjct: 814 TKA-YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM---QQ 869
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LE+ N E++ +++ Q+YE D +Q + +++
Sbjct: 870 LEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/407 (20%), Positives = 177/407 (43%), Gaps = 41/407 (10%)
Query: 46 DLESERELRQR----IEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELL 97
DLE+ER L + +E +K D+ ++ IQ+ + +++ E S+ E K T++
Sbjct: 830 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK-QNSEMEQKVKSLTQVY 888
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE----QIDQLTKTKARAEKEKSKFQAEV 153
+ + LED + E E+T +L +K + +++ +E +I+ LT+ K A+++ E
Sbjct: 889 ESK--LEDGNKEQEQTKQILVEK-ENMILQMREGQKKEIEILTQ-KLSAKEDSIHILNEE 944
Query: 154 YE--LLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENI 210
YE Q + + K K + E L+ + + K++ EL T ++++ Q+ Q N
Sbjct: 945 YETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS---QKEKQFNA 1001
Query: 211 ELVKEVQDLKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXX-XASLHQVEIDLESV 268
++++ Q I + V L++ Q L+Q +L+ +
Sbjct: 1002 KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI 1061
Query: 269 R-VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+QL+E+ + +L+++++ E + K
Sbjct: 1062 HEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV--------KQDTTLNELQE 1113
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
A +N++ + +++L++ +E L +DL K+ LQ EQL +E+K EE
Sbjct: 1114 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ---EQL----VELKMLAEE 1166
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + L+ E Q + +K+ + + + E KK+ ++L
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1213
Score = 46.8 bits (106), Expect = 2e-04
Identities = 81/422 (19%), Positives = 171/422 (40%), Gaps = 23/422 (5%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIERE--KADLSVQVIQLSERLEEAEGGAESQ 85
++ +A LE + Q E+ R+L+ ++ + + + + ++S + E + E
Sbjct: 408 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 467
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + ++ KL+KL E E+ L KK Q +FQEQ+ ++ K+++E
Sbjct: 468 DVMKKSSEEQIAKLQKLHEKELARKEQE---LTKKLQTREREFQEQM-KVALEKSQSEYL 523
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K + E E LA E ++K ++++ +L +L + E I+++ S ++
Sbjct: 524 KISQEKEQQESLALEELELQKKAILTESENKLR----DLQQEAETYRTRILELESSLEKS 579
Query: 206 SQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
QEN K++ + + N N + Q +
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRS------KFXXXXXXXXXXXXXXXX 316
++E +R + E+E E L + + +A+ E + ++ K
Sbjct: 640 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 699
Query: 317 KYSXXXXXXXXXXXTLIAKIN---NVEKQKSRLQSEVEVLIIDLEKA-NGTARELQKRTE 372
++ T K +++QK+ Q +V+ +I + E + T + L+ +
Sbjct: 700 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 759
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
QLE + E L+E E + D++ + ELQ+ S +LD + + A + K +
Sbjct: 760 QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 819
Query: 433 DL 434
L
Sbjct: 820 QL 821
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/399 (18%), Positives = 162/399 (40%), Gaps = 48/399 (12%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLES---ERELRQR----IEREKADLSVQVIQLSER 74
+NI + L E++I+ ++ D+ES E+E Q+ ++ ++ + QL +
Sbjct: 1288 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1347
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
L E E +++ E+ L K L D++++ + + L +K + + ++Q D+
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEK--EAAISSLRKQYDE 1405
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
EK + +V +L +V+ ++KEKI+ + + SE K +
Sbjct: 1406 ----------EKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS---- 1451
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
T H+ + + I+L + ++ E + LK ++ Q
Sbjct: 1452 --RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQ----NKRFDCLKGEMEDD 1505
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ + + E +LE+ +L+ ++ ++LE + + EI
Sbjct: 1506 KSKMEKKESNLET---ELKSQTARIMELEDHITQKTIEI---------------ESLNEV 1547
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE-KANGTARELQKRTEQ 373
Y+ + + ++K E E I+ LE + EL+ + ++
Sbjct: 1548 LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE 1607
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHE 412
LE VN+ +KS+ EE L ++ + + K EL+R + +
Sbjct: 1608 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ 1646
Score = 46.0 bits (104), Expect = 3e-04
Identities = 88/432 (20%), Positives = 170/432 (39%), Gaps = 39/432 (9%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ R E+ ++ ++ ++S +E + EK L Q L ERL+E E + K
Sbjct: 288 VKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQ---LDERLQELEKIKDLHMAEKTKL 344
Query: 93 DTELLKLRKLLED-------VHLESEETAHLLKKKNQEIVIDFQEQIDQLTK--TKARAE 143
T+L + L+E V E++ H + +E + + +I Q+T + R +
Sbjct: 345 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ 404
Query: 144 KEKSKFQA--EVYELLAQVENV----TKEKITISKTCERLEITISELHIKI-EELNRTIV 196
KEKS+ A E+ + L+ + K K + + + +E T E I + +EL+R
Sbjct: 405 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQ 464
Query: 197 DITSHKQRLSQENI---------ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
++ ++ S+E I EL ++ Q+L ++ +
Sbjct: 465 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 524
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
SL E++L+ + E E++ R DL+++ I S
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKSLQEN 583
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAK----INNVEKQKSRLQSE-VEVLIIDLEKANG 362
++ K + +++ Q+ L +E ++VL +
Sbjct: 584 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 643
Query: 363 TAREL--QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
RE Q++ L+ I ++ +EE + E+T L KQTEL+ +S EL + + +
Sbjct: 644 KLREKCEQEKETLLKDKEIIFQAHIEE---MNEKTLEKLDVKQTELESLSSELSEVLKAR 700
Query: 421 DALARENKKMGD 432
L E + D
Sbjct: 701 HKLEEELSVLKD 712
Score = 45.2 bits (102), Expect = 6e-04
Identities = 64/362 (17%), Positives = 143/362 (39%), Gaps = 24/362 (6%)
Query: 98 KLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LR+L E+ +++ ++ H L++K +I + I+ L K +KE Q
Sbjct: 1277 QLRQLTEEQNTLNISFQQATHQLEEKENQIK-SMKADIESLVTEKEALQKEGGNQQQAAS 1335
Query: 155 ELLAQVENVTKE------KITISKT-CERLEITISELHIKIEELNRTIVD---------- 197
E + + + KE +T+ K + ++ IS L ++ +LN + +
Sbjct: 1336 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAA 1395
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
I+S +++ +E EL+ +VQDL ++ + K Q
Sbjct: 1396 ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQ 1455
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
HQ + + +++QLE +S+ + + Q+ E+ +F K
Sbjct: 1456 -HQNTV--KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKK 1512
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S ++ +++ ++ ++S EVL ++ + +EL ++ + + +
Sbjct: 1513 ESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQEL 1572
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
E +R++E + + + + + EL+ EL+ + E K + D L
Sbjct: 1573 GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1632
Query: 438 RA 439
A
Sbjct: 1633 SA 1634
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 29 DLSALSRLEDKIRLIQDDLESER-----ELRQRIEREKADLSVQVI-QLSERLEEAEGGA 82
+LS S+ E++++ ++D LESE EL+++ E++ A + Q++ Q+ E+ E+ + G
Sbjct: 1612 NLSVKSK-EEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGT 1670
Query: 83 ESQF-EINRK---RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
ES E+N K R+ E+ L + L+ V ET + + QE+ D
Sbjct: 1671 ESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV 1730
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+ E++ S Q + E ++ V +EK + + E IK+E
Sbjct: 1731 QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLE 1781
Score = 35.9 bits (79), Expect = 0.34
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 26/200 (13%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQ----VIQLSERLEEAEGGAESQFEINRKR 92
+ ++ +++ + + ERE ++I++E+ DL ++ + QL E + E+ K
Sbjct: 1961 QQELEILKKEYDQERE--EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK- 2017
Query: 93 DTELLKLRKLLEDVHLES--EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK----EK 146
E + + +E LES EET LLKK E+ D L +T R E+ +
Sbjct: 2018 --ETINKAQEVEAELLESHQEETNQLLKK--------IAEKDDDLKRTAKRYEEILDARE 2067
Query: 147 SKFQAEVYELLAQVENVTK---EKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ A+V +L Q+E + K +K+ + +TI EL ++ + I D +Q
Sbjct: 2068 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 2127
Query: 204 RLSQENIELVKEVQDLKVNI 223
++ L ++ + N+
Sbjct: 2128 EFREQIHNLEDRLKKYEKNV 2147
Score = 33.5 bits (73), Expect = 1.8
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 35 RLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
RL+ +R+++ + + E E L++ ++E+ + ++ Q E LE Q + R+ +
Sbjct: 1948 RLQKDLRMLRKEHQQELEILKKEYDQEREE---KIKQEQEDLELKHNSTLKQ--LMREFN 2002
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
T+L + + LE + +ET + ++ E++ QE+ +QL K A + + +
Sbjct: 2003 TQLAQKEQELE---MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRY 2059
Query: 154 YELL-AQVENVTKEKITISKTCERLE 178
E+L A+ E +T + + E L+
Sbjct: 2060 EEILDAREEEMTAKVRDLQTQLEELQ 2085
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 57.6 bits (133), Expect = 1e-07
Identities = 94/434 (21%), Positives = 181/434 (41%), Gaps = 47/434 (10%)
Query: 1 MSAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESER-ELRQRIER 59
M K K S TD+N++ +S LS E I ++ + E+ EL +++
Sbjct: 1213 MKEELKEKKVEISSLSKQLTDLNVQLQNSIS-LSEKEAAISSLRKQYDEEKCELLDQVQ- 1270
Query: 60 EKADLSVQVIQLSER----LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
DLS +V LS+ LE+ + + E +K + + + ++++ ++ E +
Sbjct: 1271 ---DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSK 1327
Query: 116 LLKKKNQEIVIDFQEQIDQLTKT----KARAEKEKSKFQAEVYELLAQVENVTKEKITIS 171
+K+++I + +E++DQ K K E +KSK + + L ++++ T + +
Sbjct: 1328 EAYEKDEQINL-LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELE 1386
Query: 172 KTCERLEITISELHIKIEELN-------RTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ I I L+ ++ N + +V H Q L +E VKE ++ + +E
Sbjct: 1387 DHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLE 1446
Query: 225 NVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL-DL 282
N VY +K+++ ++ S+ E +L+++ +LE ES A+L +L
Sbjct: 1447 NQVYSMKAELETK-----------KKELEHVNLSVKSKEEELKALEDRLESESAAKLAEL 1495
Query: 283 ERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQ 342
+R KA +I + + + + + EK
Sbjct: 1496 KR---KAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILE--EKL 1550
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
KS S+ E LI+ N A Q+ + V + EE + + QR+L K
Sbjct: 1551 KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV----QKTYEEKISV---LQRNLTEK 1603
Query: 403 QTELQRVSHELDKT 416
+ LQRV E ++T
Sbjct: 1604 EKLLQRVGQEKEET 1617
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/407 (20%), Positives = 177/407 (43%), Gaps = 41/407 (10%)
Query: 46 DLESERELRQR----IEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELL 97
DLE+ER L + +E +K D+ ++ IQ+ + +++ E S+ E K T++
Sbjct: 685 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK-QNSEMEQKVKSLTQVY 743
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE----QIDQLTKTKARAEKEKSKFQAEV 153
+ + LED + E E+T +L +K + +++ +E +I+ LT+ K A+++ E
Sbjct: 744 ESK--LEDGNKEQEQTKQILVEK-ENMILQMREGQKKEIEILTQ-KLSAKEDSIHILNEE 799
Query: 154 YE--LLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENI 210
YE Q + + K K + E L+ + + K++ EL T ++++ Q+ Q N
Sbjct: 800 YETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS---QKEKQFNA 856
Query: 211 ELVKEVQDLKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXX-XASLHQVEIDLESV 268
++++ Q I + V L++ Q L+Q +L+ +
Sbjct: 857 KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI 916
Query: 269 R-VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+QL+E+ + +L+++++ E + K
Sbjct: 917 HEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV--------KQDTTLNELQE 968
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
A +N++ + +++L++ +E L +DL K+ LQ EQL +E+K EE
Sbjct: 969 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ---EQL----VELKMLAEE 1021
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + L+ E Q + +K+ + + + E KK+ ++L
Sbjct: 1022 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1068
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/399 (18%), Positives = 162/399 (40%), Gaps = 48/399 (12%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLES---ERELRQR----IEREKADLSVQVIQLSER 74
+NI + L E++I+ ++ D+ES E+E Q+ ++ ++ + QL +
Sbjct: 1143 LNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1202
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
L E E +++ E+ L K L D++++ + + L +K + + ++Q D+
Sbjct: 1203 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEK--EAAISSLRKQYDE 1260
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
EK + +V +L +V+ ++KEKI+ + + SE K +
Sbjct: 1261 ----------EKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS---- 1306
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
T H+ + + I+L + ++ E + LK ++ Q
Sbjct: 1307 --RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQ----NKRFDCLKGEMEDD 1360
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
+ + + E +LE+ +L+ ++ ++LE + + EI
Sbjct: 1361 KSKMEKKESNLET---ELKSQTARIMELEDHITQKTIEI---------------ESLNEV 1402
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE-KANGTARELQKRTEQ 373
Y+ + + ++K E E I+ LE + EL+ + ++
Sbjct: 1403 LKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKE 1462
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHE 412
LE VN+ +KS+ EE L ++ + + K EL+R + +
Sbjct: 1463 LEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ 1501
Score = 46.0 bits (104), Expect = 3e-04
Identities = 82/424 (19%), Positives = 166/424 (39%), Gaps = 27/424 (6%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIERE--KADLSVQVIQLSERLEEAEGGAESQ 85
++ +A LE + Q E+ R+L+ ++ + + + + ++S + E + E
Sbjct: 263 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 322
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + ++ KL+KL E E+ L KK Q +FQEQ+ ++ K+++E
Sbjct: 323 DVMKKSSEEQIAKLQKLHEKELARKEQE---LTKKLQTREREFQEQM-KVALEKSQSEYL 378
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K + E E LA E ++K ++++ +L +L + E I+++ S ++
Sbjct: 379 KISQEKEQQESLALEELELQKKAILTESENKLR----DLQQEAETYRTRILELESSLEKS 434
Query: 206 SQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
QEN K++ + + N N + Q +
Sbjct: 435 LQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQ 494
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
++E +R + E+E E L + + +A+ I K + S
Sbjct: 495 TEMEKLREKCEQEKETLLKDKEIIFQAH--IEEMNEKTLEKLDVNQTELESLSSELSEVL 552
Query: 323 XXXXXXXXTLIAKINNVEKQKSRL-----------QSEVEVLIIDLEKA-NGTARELQKR 370
L + +K K L Q +V+ +I + E + T + L+ +
Sbjct: 553 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ 612
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
QLE + E L+E E + D++ + ELQ+ S +LD + + A + K
Sbjct: 613 INQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAY 672
Query: 431 GDDL 434
+ L
Sbjct: 673 EEQL 676
Score = 46.0 bits (104), Expect = 3e-04
Identities = 70/368 (19%), Positives = 153/368 (41%), Gaps = 18/368 (4%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF-EINRKRDTELLKLRKLLEDV 106
ESE +LR +++E ++++L LE++ E+Q ++ + E K K + V
Sbjct: 405 ESENKLRD-LQQEAETYRTRILELESSLEKSLQENENQSKDLAVHLEAEKNKHNKEIT-V 462
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKT-KARAEKEKSKFQAEVYELLAQVENVTK 165
+E +T L K+Q+ + + E++ L + + EK + K + E LL E + +
Sbjct: 463 MVEKHKT-ELESLKHQQDAL-WAEELQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 520
Query: 166 EKITI--SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNI 223
I KT E+L++ +EL E L+ + ++ + +L +E L + +K +
Sbjct: 521 AHIEEMNEKTLEKLDVNQTEL----ESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 576
Query: 224 ENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS--LHQVEIDLESVRVQLEEESEARLD 281
E + + Q ++Q+E+ L+ L+E +
Sbjct: 577 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVEN 636
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
LE + ++ GE+ +K Y L + + K
Sbjct: 637 LEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA-YEEQLAQLQQKLLDLETERILLTK 695
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q + ++++ + + +L+ ++L +QLE+ N E++ +++ Q+YE D
Sbjct: 696 QVAEVEAQKKDVCTELDAHKIQVQDLM---QQLEKQNSEMEQKVKSLTQVYESKLEDGNK 752
Query: 402 KQTELQRV 409
+Q + +++
Sbjct: 753 EQEQTKQI 760
Score = 45.2 bits (102), Expect = 6e-04
Identities = 64/362 (17%), Positives = 143/362 (39%), Gaps = 24/362 (6%)
Query: 98 KLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+LR+L E+ +++ ++ H L++K +I + I+ L K +KE Q
Sbjct: 1132 QLRQLTEEQNTLNISFQQATHQLEEKENQIK-SMKADIESLVTEKEALQKEGGNQQQAAS 1190
Query: 155 ELLAQVENVTKE------KITISKT-CERLEITISELHIKIEELNRTIVD---------- 197
E + + + KE +T+ K + ++ IS L ++ +LN + +
Sbjct: 1191 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAA 1250
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
I+S +++ +E EL+ +VQDL ++ + K Q
Sbjct: 1251 ISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQ 1310
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
HQ + + +++QLE +S+ + + Q+ E+ +F K
Sbjct: 1311 -HQNTV--KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKK 1367
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
S ++ +++ ++ ++S EVL ++ + +EL ++ + + +
Sbjct: 1368 ESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQEL 1427
Query: 378 NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
E +R++E + + + + + EL+ EL+ + E K + D L
Sbjct: 1428 GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1487
Query: 438 RA 439
A
Sbjct: 1488 SA 1489
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/171 (25%), Positives = 82/171 (47%), Gaps = 11/171 (6%)
Query: 29 DLSALSRLEDKIRLIQDDLESER-----ELRQRIEREKADLSVQVI-QLSERLEEAEGGA 82
+LS S+ E++++ ++D LESE EL+++ E++ A + Q++ Q+ E+ E+ + G
Sbjct: 1467 NLSVKSK-EEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGT 1525
Query: 83 ESQF-EINRK---RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
ES E+N K R+ E+ L + L+ V ET + + QE+ D
Sbjct: 1526 ESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCV 1585
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE 189
+ E++ S Q + E ++ V +EK + + E IK+E
Sbjct: 1586 QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLE 1636
Score = 44.0 bits (99), Expect = 0.001
Identities = 87/432 (20%), Positives = 168/432 (38%), Gaps = 39/432 (9%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ R E+ ++ ++ ++S +E + EK L Q L ERL+E E + K
Sbjct: 143 VKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQ---LDERLQELEKIKDLHMAEKTKL 199
Query: 93 DTELLKLRKLLED-------VHLESEETAHLLKKKNQEIVIDFQEQIDQLTK--TKARAE 143
T+L + L+E V E++ H + +E + + +I Q+T + R +
Sbjct: 200 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ 259
Query: 144 KEKSKFQA--EVYELLAQVENV----TKEKITISKTCERLEITISELHIKI-EELNRTIV 196
KEKS+ A E+ + L+ + K K + + + +E T E I + +EL+R
Sbjct: 260 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQ 319
Query: 197 DITSHKQRLSQENI---------ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
++ ++ S+E I EL ++ Q+L ++ +
Sbjct: 320 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 379
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
SL E++L+ + E E++ R DL+++ I S
Sbjct: 380 ISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKSLQEN 438
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAK----INNVEKQKSRL-QSEVEVLIIDLEKANG 362
++ K + +++ Q+ L E++VL +
Sbjct: 439 ENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQTEME 498
Query: 363 TAREL--QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
RE Q++ L+ I ++ +EE + E+T L QTEL+ +S EL + + +
Sbjct: 499 KLREKCEQEKETLLKDKEIIFQAHIEE---MNEKTLEKLDVNQTELESLSSELSEVLKAR 555
Query: 421 DALARENKKMGD 432
L E + D
Sbjct: 556 HKLEEELSVLKD 567
Score = 35.9 bits (79), Expect = 0.34
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 26/200 (13%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQ----VIQLSERLEEAEGGAESQFEINRKR 92
+ ++ +++ + + ERE ++I++E+ DL ++ + QL E + E+ K
Sbjct: 1816 QQELEILKKEYDQERE--EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK- 1872
Query: 93 DTELLKLRKLLEDVHLES--EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK----EK 146
E + + +E LES EET LLKK E+ D L +T R E+ +
Sbjct: 1873 --ETINKAQEVEAELLESHQEETNQLLKK--------IAEKDDDLKRTAKRYEEILDARE 1922
Query: 147 SKFQAEVYELLAQVENVTK---EKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ A+V +L Q+E + K +K+ + +TI EL ++ + I D +Q
Sbjct: 1923 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQ 1982
Query: 204 RLSQENIELVKEVQDLKVNI 223
++ L ++ + N+
Sbjct: 1983 EFREQIHNLEDRLKKYEKNV 2002
Score = 33.5 bits (73), Expect = 1.8
Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 10/146 (6%)
Query: 35 RLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
RL+ +R+++ + + E E L++ ++E+ + ++ Q E LE Q + R+ +
Sbjct: 1803 RLQKDLRMLRKEHQQELEILKKEYDQEREE---KIKQEQEDLELKHNSTLKQ--LMREFN 1857
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV 153
T+L + + LE + +ET + ++ E++ QE+ +QL K A + + +
Sbjct: 1858 TQLAQKEQELE---MTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRY 1914
Query: 154 YELL-AQVENVTKEKITISKTCERLE 178
E+L A+ E +T + + E L+
Sbjct: 1915 EEILDAREEEMTAKVRDLQTQLEELQ 1940
>AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens
cDNA FLJ32111 fis, clone OCBBF2001528, weakly similar to
MYOSIN HEAVY CHAIN, SMOOTH MUSCLE ISOFORM. ).
Length = 883
Score = 57.6 bits (133), Expect = 1e-07
Identities = 56/266 (21%), Positives = 109/266 (40%), Gaps = 13/266 (4%)
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
++KSK EV EL Q++ K + I + ER+ + EL + N + + ++ +Q
Sbjct: 614 EQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELR---SQHNEKVEENSTLQQ 670
Query: 204 RLSQENIELVKEVQDL-KVNIENVVY------LKSQIASQXXXXXXXXXXXXXXXXXXXA 256
RL + EL K +++L +V +E + L+ Q++
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
L Q + DL+ + + EE+ + ER+L G + S
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L ++ N E+ ++ + V++L + E G + EL++R QL+R
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENENLQGRSEELERRVAQLQR 850
Query: 377 VNIEIK---SRLEETVQLYEQTQRDL 399
++K ++ +ET++ +E R L
Sbjct: 851 QIEDLKGDEAKAKETLKKFEGEIRQL 876
Score = 57.6 bits (133), Expect = 1e-07
Identities = 39/186 (20%), Positives = 87/186 (46%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE+ ++ +LE +++ E+ + ++ QLSE +E + S+
Sbjct: 671 RLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIE 730
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
ELL+ ++ L+D+ + EE LL+K+ +E+ ++++ +K K ++ AE+
Sbjct: 731 ELLQAKQDLQDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQ 790
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
L VE TK ++ E + ++++ L ++ + L + +L +
Sbjct: 791 ALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENENLQGRSEELERRVAQLQR 850
Query: 215 EVQDLK 220
+++DLK
Sbjct: 851 QIEDLK 856
Score = 40.7 bits (91), Expect = 0.012
Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 15/198 (7%)
Query: 44 QDDLESERE-LRQRIEREKADLSVQVIQ---LSERLEEAEG----GAESQFEINRKRD-- 93
Q +++ ERE +R +E ++ + +V + L +RLEE+EG E F++ +R+
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 94 -TELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKSKF 149
TE+ L+ L ++H E + ++ ++ + ++ + L K E K
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKR 756
Query: 150 QAEVYELL-AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E+ L A E V+ + K E+ + + L +EE + + + S Q+
Sbjct: 757 ERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQD 816
Query: 209 NIELVKEVQDLKVNIENV 226
V+ L+ EN+
Sbjct: 817 QAGTEMRVKLLQEENENL 834
Score = 32.3 bits (70), Expect = 4.2
Identities = 25/112 (22%), Positives = 55/112 (49%), Gaps = 7/112 (6%)
Query: 334 AKINNVEKQKSRLQSEV----EVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
+++ ++ +QKS+L EV L ++++ E ++ LE + + ++EE
Sbjct: 607 SEVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENS 666
Query: 390 QLY---EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L E+++ +LR EL +V E ++ + + L + +M D+L A+
Sbjct: 667 TLQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAK 718
Score = 31.1 bits (67), Expect = 9.7
Identities = 29/128 (22%), Positives = 62/128 (48%), Gaps = 8/128 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 753 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 812
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 813 SEQDQAGTEMRVKLLQEENENLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 868
Query: 149 FQAEVYEL 156
F+ E+ +L
Sbjct: 869 FEGEIRQL 876
>BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein
protein.
Length = 724
Score = 56.8 bits (131), Expect = 2e-07
Identities = 86/410 (20%), Positives = 155/410 (37%), Gaps = 18/410 (4%)
Query: 27 SADLSA-LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
++DL ++ + +LIQ++L + ++E E Q++ L ++LEE S
Sbjct: 259 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSI 318
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
N + + EL+ L LE + +E + Q+I+ Q ++ L + ++ E
Sbjct: 319 AAKNAELEQELM-LEAQLEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKGE 376
Query: 146 KSKFQAEVYELLAQVEN-VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + E L ++N V++E I + + LEI EL + + +L ++
Sbjct: 377 MKKENMKKDEALKALQNQVSEETIKVRQLDSALEIRKEELVLHLNQLEGNKEKFEKQLKK 436
Query: 205 LSQENIELVKEVQ----DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
S+E L KE++ L+ E V L+ + Q Q
Sbjct: 437 KSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQ 496
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
V + ++ Q E +E +E + A E R K +Y
Sbjct: 497 VSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMD-QYKE 555
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L N S+L ++ +LEK +EL+K E
Sbjct: 556 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE----- 610
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENK 428
+ L E +Q E + +L+N EL+ +L + R+ QK L+ E K
Sbjct: 611 --TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 658
Score = 37.9 bits (84), Expect = 0.084
Identities = 42/204 (20%), Positives = 96/204 (47%), Gaps = 20/204 (9%)
Query: 34 SRLEDKIRLIQDDLESEREL---RQRIEREKADLSVQVIQLS-ERLEEAEGGAES-QFEI 88
++LE ++ ++ +L+ +RE + R EK + + L +++ E G A + E+
Sbjct: 491 TKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 550
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID-FQEQIDQLTKTKARAEKEKS 147
++ ++ EL K+ K E +HL+ + + ++++D + ++++ T EK +
Sbjct: 551 DQYKE-ELSKMEK--EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH 607
Query: 148 KFQAEVYELL-------AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ E+ E L +++N E + + + L + + + +EE TI D+T+
Sbjct: 608 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 667
Query: 201 H----KQRLSQENIELVKEVQDLK 220
K + + EL++ Q LK
Sbjct: 668 ELRECKMEIEDKKQELLEMDQALK 691
Score = 35.1 bits (77), Expect = 0.59
Identities = 73/422 (17%), Positives = 171/422 (40%), Gaps = 23/422 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L L++K+R ++++ + +E + + + +++ Q+ + + + + E E++ EI R
Sbjct: 16 SELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILR 75
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ + + + R+L V ++E L QEI + ++ L K ++ ++ F
Sbjct: 76 DKFSLMNENRELKVRVAAQNER----LDLCQQEIESS-RVELRSLEKIISQLPLKRELFG 130
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKI----EELNRTIVDITSHKQRLS 206
+ Y Q+ + + ++ CE ++ ISEL IK+ E+ + ++T++ +LS
Sbjct: 131 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTAN--QLS 188
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
Q I + K++ +K + + +E
Sbjct: 189 QSLITCNDSQESSKLSSLETEPVK--LGGHQVAESVKDQNQHTMNKQYEKERQGLVTGIE 246
Query: 267 SVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
+R +L + DL+ + + + + K S
Sbjct: 247 ELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEK 306
Query: 327 XXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE 386
++A +++ + + L+ E+ +L LEK + +E +K L++ I + LE
Sbjct: 307 QLEEKIVA-YSSIAAKNAELEQEL-MLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLE 364
Query: 387 ETVQLYEQTQRDLRNKQTE-------LQ-RVSHELDKTREQKDALARENKKMGDDLHDAR 438
+L +++ +++ + + LQ +VS E K R+ AL +++ L+
Sbjct: 365 SLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEIRKEELVLHLNQLE 424
Query: 439 AN 440
N
Sbjct: 425 GN 426
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 56.8 bits (131), Expect = 2e-07
Identities = 84/417 (20%), Positives = 159/417 (38%), Gaps = 36/417 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDT 94
LE ++ ++ LE + Q E K L V + L + E + + E E R+
Sbjct: 63 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQR 122
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+L + LED + A KKK + + D + Q D K + A K+ K QA++
Sbjct: 123 QLHEYETELEDER-KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMK 181
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
+ ++E+ + I T + E L + +L + +++ E EL +
Sbjct: 182 DFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE 241
Query: 215 E----------VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
E +QD K +E + +Q+ + Q+ +
Sbjct: 242 ELASSLSGRNALQDEKRRLEARI---AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 298
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
L + R ++ AR LERQ N E+ RSK K+
Sbjct: 299 LATERSTAQKNESARQQLERQ----NKEL---RSKL-------HEMEGAVKSKFK----- 339
Query: 325 XXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSR 384
L AKI +E+Q + E + L++ + +E+ + E ++ + K +
Sbjct: 340 --STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQ 397
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
E+ +Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 398 AEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 454
Score = 56.4 bits (130), Expect = 2e-07
Identities = 64/377 (16%), Positives = 139/377 (36%), Gaps = 13/377 (3%)
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
++ + + +++ + K E+ +AE+ +L++ ++V K + K+ LE
Sbjct: 5 REKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALE 64
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV--QDLKVNIENVVYLKSQIASQ 236
+ E+ ++EEL + K RL + N++ +K +DL+ E + Q+ Q
Sbjct: 65 TQMEEMKTQLEELEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 123
Query: 237 XXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHW 296
A+ ++E DL+ + +Q + + R + +QL K ++ +
Sbjct: 124 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 183
Query: 297 RSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIID 356
+ + L + E+ + + E E L +
Sbjct: 184 QRELEDARASRDEIFATAKEN-EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 242
Query: 357 LEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL--- 413
L + LQ +LE +++ LEE E +R + +++S+EL
Sbjct: 243 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE 302
Query: 414 ----DKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXTAAY 469
K + L R+NK++ LH+ + A
Sbjct: 303 RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEA-- 360
Query: 470 KEAEAGRKAEEQRSQRL 486
+E +A K+ +Q+ ++L
Sbjct: 361 REKQAATKSLKQKDKKL 377
Score = 52.8 bits (121), Expect = 3e-06
Identities = 61/336 (18%), Positives = 128/336 (38%), Gaps = 8/336 (2%)
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
R+++T+ L L + LE+ LE++E K + + D D + K EK K
Sbjct: 5 REKETKALSLARALEEA-LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 63
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ ++ E+ Q+E + E RLE+ + L + E + + K+R Q
Sbjct: 64 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 123
Query: 210 I-ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
+ E E++D + K ++ L +++ ++
Sbjct: 124 LHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDF 183
Query: 269 RVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
+ +LE+ +R D K N + +
Sbjct: 184 QRELEDARASR-DEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEE 242
Query: 329 XXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSR 384
+ ++ N ++ +K RL++ + L +LE+ G + ++K T+Q E+++ E+ +
Sbjct: 243 LASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE 302
Query: 385 LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
T Q E ++ L + EL+ HE++ + K
Sbjct: 303 -RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSK 337
Score = 50.0 bits (114), Expect = 2e-05
Identities = 38/182 (20%), Positives = 81/182 (44%), Gaps = 1/182 (0%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ ++ + +LE ER+ R K L + L + + A G E + RK
Sbjct: 119 QLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQA 178
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
++ ++ LED +E K+N++ + + QL + A AE+ + + E
Sbjct: 179 QMKDFQRELEDARASRDE-IFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 237
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
EL ++ + + + RLE I++L ++EE + ++ ++ +Q+ +L
Sbjct: 238 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSN 297
Query: 215 EV 216
E+
Sbjct: 298 EL 299
Score = 48.8 bits (111), Expect = 5e-05
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 259 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 318
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 319 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 378
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 379 EILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRE 432
Score = 33.1 bits (72), Expect = 2.4
Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 364 ARELQKRTEQLERV---NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
ARE + + L R +E K LE T ++ + DL + + ++ + HEL+K++
Sbjct: 4 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 63
Query: 421 DALARENKKMGDDLHD 436
+ E K ++L D
Sbjct: 64 ETQMEEMKTQLEELED 79
Score = 32.7 bits (71), Expect = 3.2
Identities = 24/98 (24%), Positives = 47/98 (47%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + +V QL +LEEAE ++
Sbjct: 362 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQR 421
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 422 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 459
Score = 31.9 bits (69), Expect = 5.5
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 340 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 399
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 400 KGNARVKQLKRQLEEAEEESQRINANRRKLQREL 433
>AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 720
Score = 56.8 bits (131), Expect = 2e-07
Identities = 86/410 (20%), Positives = 155/410 (37%), Gaps = 18/410 (4%)
Query: 27 SADLSA-LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
++DL ++ + +LIQ++L + ++E E Q++ L ++LEE S
Sbjct: 258 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSI 317
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
N + + EL+ L LE + +E + Q+I+ Q ++ L + ++ E
Sbjct: 318 AAKNAELEQELM-LEAQLEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKGE 375
Query: 146 KSKFQAEVYELLAQVEN-VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + E L ++N V++E I + + LEI EL + + +L ++
Sbjct: 376 MKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKK 435
Query: 205 LSQENIELVKEVQ----DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
S+E L KE++ L+ E V L+ + Q Q
Sbjct: 436 KSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQ 495
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
V + ++ Q E +E +E + A E R K +Y
Sbjct: 496 VSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMD-QYKE 554
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L N S+L ++ +LEK +EL+K E
Sbjct: 555 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE----- 609
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENK 428
+ L E +Q E + +L+N EL+ +L + R+ QK L+ E K
Sbjct: 610 --TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 657
Score = 37.9 bits (84), Expect = 0.084
Identities = 42/204 (20%), Positives = 96/204 (47%), Gaps = 20/204 (9%)
Query: 34 SRLEDKIRLIQDDLESEREL---RQRIEREKADLSVQVIQLS-ERLEEAEGGAES-QFEI 88
++LE ++ ++ +L+ +RE + R EK + + L +++ E G A + E+
Sbjct: 490 TKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 549
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID-FQEQIDQLTKTKARAEKEKS 147
++ ++ EL K+ K E +HL+ + + ++++D + ++++ T EK +
Sbjct: 550 DQYKE-ELSKMEK--EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH 606
Query: 148 KFQAEVYELL-------AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ E+ E L +++N E + + + L + + + +EE TI D+T+
Sbjct: 607 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 666
Query: 201 H----KQRLSQENIELVKEVQDLK 220
K + + EL++ Q LK
Sbjct: 667 ELRECKMEIEDKKQELLEMDQALK 690
Score = 34.7 bits (76), Expect = 0.79
Identities = 33/158 (20%), Positives = 78/158 (49%), Gaps = 5/158 (3%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L L++K+R ++++ + +E + + + +++ Q+ + + + + E E++ EI R
Sbjct: 16 SELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILR 75
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ + + + R+L V ++E L QEI + ++ L K ++ ++ F
Sbjct: 76 DKFSLMNENRELKVRVAAQNER----LDLCQQEIESS-RVELRSLEKIISQLPLKRELFG 130
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+ Y Q+ + + ++ CE ++ ISEL IK+
Sbjct: 131 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKL 168
Score = 32.3 bits (70), Expect = 4.2
Identities = 47/202 (23%), Positives = 90/202 (44%), Gaps = 13/202 (6%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
+L+ +L + +++ E +K ++ QLS+ L ES +++ +TE +KL
Sbjct: 158 KLVISELRIKLAIKEA-EIQKLHANLTANQLSQSLITCNDSQESS-KLS-SLETEPVKLG 214
Query: 101 -KLLEDVHLESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKEK-------SKFQA 151
+E V +++ T + +K+ Q +V +E +L + +A K S+FQ
Sbjct: 215 GHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQL 274
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
ELL + N +K + ++K C +L +L KI + +Q L E +
Sbjct: 275 IQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMLE-AQ 333
Query: 212 LVKEVQDLKVNIENVVYLKSQI 233
L K+ Q K + + L+ I
Sbjct: 334 LEKKDQQFKEQEKTMSMLQQDI 355
>AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein.
Length = 1742
Score = 56.8 bits (131), Expect = 2e-07
Identities = 87/409 (21%), Positives = 171/409 (41%), Gaps = 34/409 (8%)
Query: 24 IEYSADLSALSRLE-DKIRLIQDDLES----ERELRQRIEREKADLSVQVIQLSERLEEA 78
+E L+AL + +KI+ ++ +LE R ++ +R + + ++ +L + E
Sbjct: 909 VEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSEL 968
Query: 79 EGGAESQFEINRKRDTELLK------LRKLLEDVHLESEETAHLLKKKNQEIVI-DFQEQ 131
E E Q ++ + TE LK ++L +DV + EE +L +K+ E+ D+++Q
Sbjct: 969 ETQKE-QIQLKLQEKTEELKEKMDNLTKQLFDDV--QKEERQRMLLEKSFELKTQDYEKQ 1025
Query: 132 IDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE--KITISKTCERLEITISELHIKIE 189
I L + + EK + Q L + E+VT + K +++ ++++ TISE +IE
Sbjct: 1026 IQSLKEEIKALKDEKMQLQH-----LVEGEHVTSDGLKAEVARLSKQVK-TISEFEKEIE 1079
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
L +D+ H Q +E E + E+ + ++ ++S+++ +
Sbjct: 1080 LLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWF 1139
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
+ +E +S + E+E EA L ++V + EI H + F
Sbjct: 1140 AYEGLKKATRVLESHFQSQKDCYEKEIEA---LNFKVVHLSQEINHLQKLFREENDINES 1196
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
S +I+ +EKQK L+ + EK G EL
Sbjct: 1197 IRHEVTRLTSENMMIPDFK-----QQISELEKQKQDLEIRLNE---QAEKMKGKLEELSN 1248
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE 418
+ + + + LE +++ + + L +K E+Q S L K E
Sbjct: 1249 QLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFE 1297
Score = 34.7 bits (76), Expect = 0.79
Identities = 43/214 (20%), Positives = 92/214 (42%), Gaps = 9/214 (4%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T D + + + L+D+ +Q +E E ++ E A LS QV +SE +E
Sbjct: 1019 TQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEI 1078
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVH---LES---EETAHLLKKKNQEIVIDFQEQI 132
E + ++ + ++ ++R+ + ++ LES E+ L ++ E + + E
Sbjct: 1079 ELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELW 1138
Query: 133 DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN 192
K +S FQ++ ++E + + + +S+ L+ E + E +
Sbjct: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIR 1198
Query: 193 RTIVDITSHKQRL---SQENIELVKEVQDLKVNI 223
+ +TS + Q+ EL K+ QDL++ +
Sbjct: 1199 HEVTRLTSENMMIPDFKQQISELEKQKQDLEIRL 1232
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 56.4 bits (130), Expect = 2e-07
Identities = 75/387 (19%), Positives = 153/387 (39%), Gaps = 16/387 (4%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRK-LLEDVH--L 108
EL+ +IE+ + D ++ L + + + E R + +++K ++ LE + L
Sbjct: 398 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKL 457
Query: 109 ESEETAHLLKKKNQEIVIDFQEQIDQLTKTK-ARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ E HL++ ++ + QE ++ K K A A +E Q + E + ++ ++
Sbjct: 458 DKAEDQHLVEM--EDTLNKLQEA--EIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQF 513
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+S E+L ++++ K E + + K++L + E++K D + +
Sbjct: 514 NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN 573
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEEESEARLDLERQL 286
S+ + + E S + ++ E + +LER+L
Sbjct: 574 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKL 633
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRL 346
++ ++ K+ K+ ++ S L
Sbjct: 634 SDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL 693
Query: 347 QSEVEVLIIDLEKANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQ 403
E+E L EKA TA + + EQ+ + E + LE+T Q + Q +L K+
Sbjct: 694 LQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKE 753
Query: 404 TELQRVSHELDKTREQKDALARENKKM 430
L+ V EL+K+ K+ L EN+KM
Sbjct: 754 NNLKNV-EELNKS---KELLTVENQKM 776
Score = 56.0 bits (129), Expect = 3e-07
Identities = 90/472 (19%), Positives = 182/472 (38%), Gaps = 30/472 (6%)
Query: 38 DKIRLIQDDLESER-ELRQRIEREKADLSVQVIQLSERLEE---AEGGAESQFEINRKRD 93
D++R + + + E+ EL ++E EK +V L R+EE +G E+Q ++ R
Sbjct: 162 DQLRTMVEAADREKVELLNQLEEEKR----KVEDLQFRVEEESITKGDLETQTKLEHARI 217
Query: 94 TEL---LKLRKLLEDV---HLESEETAHLLKKKN-QEIVIDFQEQIDQLTKTKARAEKEK 146
EL L K D LE A + +K E+ D ++ ++ + + R E K
Sbjct: 218 KELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNK 277
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQR 204
++ L Q + +EK+ +++T + EIT + H + E + I + + ++
Sbjct: 278 PAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEK 337
Query: 205 LSQENIELVKEVQDL-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLH 259
LS+EN L +++ K N + + KS+ IAS A
Sbjct: 338 LSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFA 397
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANG-EIGHWRSKFXXXXXXXXXXXXXXXXKY 318
+++ +E +R+ + E E + + A+ E+ R+K K
Sbjct: 398 ELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKL 457
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVN 378
+ K+ E +K + E + T +L ++ EQ ++
Sbjct: 458 DKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLS 517
Query: 379 IEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK----KMGDDL 434
+++ +L E + E R+ ++ +L + +L+ + ++ +N KM D+L
Sbjct: 518 SDLE-KLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDEL 576
Query: 435 HDARANITXXXXXXXXXXXXXXXXXXXXXXXT--AAYKEAEAGRKAEEQRSQ 484
++ T A + EA +K EE++ +
Sbjct: 577 RLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKE 628
Score = 51.2 bits (117), Expect = 8e-06
Identities = 75/398 (18%), Positives = 154/398 (38%), Gaps = 19/398 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 567 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 625
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 626 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 685
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 686 AREENSGLLQELEELRKQ-AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 740
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 741 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 800
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 801 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 856
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 857 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 912
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++ +R L + + E ++ +E + +
Sbjct: 913 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQQMI 950
Score = 39.9 bits (89), Expect = 0.021
Identities = 43/191 (22%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
TT +++ S S+LS + + S R R + E + + I + L+EA
Sbjct: 53 TTSASLKRSPSASSLSSMSSVASSV-----SSRPSRTGLLTETSSRYARKISGTTALQEA 107
Query: 79 EGGAESQFE-INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E + +RD E ++ K V E E+ L + + + V++ + ++DQL
Sbjct: 108 LKEKQQHIEQLLAERDLERAEVAKATSHVG-EIEQELALARDGHDQHVLELEAKMDQLRT 166
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
A++EK + ++ E +VE++ S T LE H +I+EL ++++
Sbjct: 167 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLF 226
Query: 198 ITSHKQRLSQE 208
+ +L +E
Sbjct: 227 EKTKADKLQRE 237
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 56.0 bits (129), Expect = 3e-07
Identities = 68/395 (17%), Positives = 156/395 (39%), Gaps = 12/395 (3%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RK 91
L +LE+++ + DL+ +R+ +E+++ Q++ + + G + E R+
Sbjct: 837 LKKLEEELDDLLVDLDHQRQSACNLEKKQKKFD-QLLAEEKTISAKYAGERDRAEAEARE 895
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
++T+ L L + LE+ + E L K+ E+ D D + K+ EK K +
Sbjct: 896 KETKALSLARALEEAMEQKAELERLNKQFRTEME-DLMSSKDDVGKSVHELEKSKRALEQ 954
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENI 210
+V E+ Q+E + E RLE+ + + + E +L K++L ++
Sbjct: 955 QVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1014
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ E++D + V + ++ L +++ ++
Sbjct: 1015 EMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR 1074
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
+L++ +R ++ Q + ++ ++
Sbjct: 1075 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIAN 1134
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR----ELQKRTEQLERVNIEIKSRLE 386
+ K ++K RL++ + L +LE+ G L+K Q++++N ++ LE
Sbjct: 1135 S-SGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDL--NLE 1191
Query: 387 ET-VQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ Q E ++ L + EL+ E++ T + K
Sbjct: 1192 RSHAQKNENARQQLERQNKELKVKLQEMEGTVKSK 1226
Score = 55.2 bits (127), Expect = 5e-07
Identities = 81/422 (19%), Positives = 174/422 (41%), Gaps = 25/422 (5%)
Query: 25 EYSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
E A L+A + LE+ ++ +E E E Q ++ EK + + +L E+LEE E A
Sbjct: 765 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEES-AR 823
Query: 84 SQFEINR-KRDTELLKLRKLLEDVHLESE---ETAHLLKKKNQEI--VIDFQEQID-QLT 136
+ ++ + + +L KL + L+D+ ++ + ++A L+KK ++ ++ ++ I +
Sbjct: 824 QKLQLEKVTTEAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA 883
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ RAE E + + + L +E ++K + + ++ + +L +++ +++
Sbjct: 884 GERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 943
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENV--------VYLKSQIASQXXXXXXXXXXXX 248
++ K+ L Q+ E+ ++++L+ ++ V L++ A
Sbjct: 944 ELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSE 1003
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
+ ++E +LE R Q AR LE L I +K
Sbjct: 1004 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDS-ANKNRDEAIKQL 1062
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
++A+ EK+ +++E+ L +L A R+ Q
Sbjct: 1063 RKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQ 1122
Query: 369 KRTEQL--ERVNIEIKS--RLEETVQL---YEQTQRDLRNKQTELQRVSHELDKTREQKD 421
+ ++L E N K LEE +L Q + +L +Q + ++ L K Q D
Sbjct: 1123 QERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQID 1182
Query: 422 AL 423
+
Sbjct: 1183 QI 1184
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/310 (16%), Positives = 128/310 (41%), Gaps = 8/310 (2%)
Query: 120 KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
+ +E ++ +E++ ++ + + AE ++ + +L+A+ + ++ ++ C E
Sbjct: 706 RQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEE 765
Query: 180 TISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXX 239
+ L K +EL D+ + + + L E + ++ NI+ L+ Q+ +
Sbjct: 766 LRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQE---LEEQLEEEESA 822
Query: 240 XXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSK 299
A L ++E +L+ + V L+ + ++ +LE++ K + + ++
Sbjct: 823 RQKLQLEKVTTE----AKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTI 878
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K + + K +E+ + ++E+E L+ +
Sbjct: 879 SAKYAGERDRAEAEAREKETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDD 937
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+ EL+K LE+ E+K++LEE + T+ + LQ + + ++ +
Sbjct: 938 VGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERDLQG 997
Query: 420 KDALARENKK 429
+D + E KK
Sbjct: 998 RDEQSEEKKK 1007
Score = 51.2 bits (117), Expect = 8e-06
Identities = 79/412 (19%), Positives = 161/412 (39%), Gaps = 29/412 (7%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+++++ + ELR R+ +K +L L R+EE E + +K
Sbjct: 748 QLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ 807
Query: 95 ELLKLRKLLED-------VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ +L + LE+ + LE T LKK +E+ D +D ++ EK++
Sbjct: 808 NIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEL-DDLLVDLDHQRQSACNLEKKQK 866
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
KF +LLA+ + ++ + + +R E E K L R + + K L +
Sbjct: 867 KFD----QLLAEEKTISAK---YAGERDRAEAEAREKETKALSLARALEEAMEQKAELER 919
Query: 208 ENIELVKEVQDL---KVNIENVVY----LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
N + E++DL K ++ V+ K + Q + +
Sbjct: 920 LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLR 979
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
+E++L++++ Q E + + R + + K K
Sbjct: 980 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1039
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
+ + KQ +LQ++++ + +L+ + E+ + ++ E+ +
Sbjct: 1040 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK---K 1096
Query: 381 IKSRLEETVQLYEQ---TQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+KS E +QL E+ +R R Q E ++ E+ + K ALA E K+
Sbjct: 1097 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS-SGKGALALEEKR 1147
Score = 46.4 bits (105), Expect = 2e-04
Identities = 23/97 (23%), Positives = 54/97 (55%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E + +L+ E++ L++DL+ +A L+K+ ++ +++ E K+ + ++ + +
Sbjct: 834 EAKLKKLEEELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEA 893
Query: 400 RNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
R K+T+ ++ L++ EQK L R NK+ ++ D
Sbjct: 894 REKETKALSLARALEEAMEQKAELERLNKQFRTEMED 930
Score = 44.8 bits (101), Expect = 7e-04
Identities = 29/108 (26%), Positives = 57/108 (52%), Gaps = 3/108 (2%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE-IKSRLEETVQ-LYE 393
++ +EK K L+ +VE + LE+ G + + +LE VN++ +K++ E +Q E
Sbjct: 942 VHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLE-VNLQAMKAQFERDLQGRDE 1000
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
Q++ + +++ + EL+ R+Q+ KK+ DL D A+I
Sbjct: 1001 QSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHI 1048
Score = 42.3 bits (95), Expect = 0.004
Identities = 34/160 (21%), Positives = 78/160 (48%), Gaps = 8/160 (5%)
Query: 35 RLEDKIRLIQDDLESERELRQRIER--EKADLSVQVIQLSERLEE--AEGGAESQFEINR 90
RLE +I ++++LE E+ + I +KA+L + I LE A+ ++ ++ R
Sbjct: 1148 RLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLER 1207
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ +KL+++ V + + + L+ K + +EQ+D TK + A K+ + +
Sbjct: 1208 QNKELKVKLQEMEGTVKSKYKASITALEAK----IAQLEEQLDNETKERQAACKQVRRTE 1263
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
++ ++L QV++ + ++ + +L ++EE
Sbjct: 1264 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEE 1303
Score = 33.1 bits (72), Expect = 2.4
Identities = 26/151 (17%), Positives = 67/151 (44%), Gaps = 9/151 (5%)
Query: 17 GGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
G T +N + ++ + L + + RQ++ER+ +L V +L+
Sbjct: 1165 GNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKV-------KLQ 1217
Query: 77 EAEGGAESQFEIN-RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL 135
E EG +S+++ + + ++ +L + L++ E + +++ +++ D Q+D
Sbjct: 1218 EMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLK-DVLLQVDDE 1276
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ + + + K + +L Q+E +E
Sbjct: 1277 RRNAEQYKDQADKASTRLKQLKRQLEEAEEE 1307
Score = 31.1 bits (67), Expect = 9.7
Identities = 19/80 (23%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Query: 358 EKANGTARELQKRTEQLERV---NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
++A ARE + + L R +E K+ LE + + DL + + ++ + HEL+
Sbjct: 887 DRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELE 946
Query: 415 KTREQKDALARENKKMGDDL 434
K++ + E K ++L
Sbjct: 947 KSKRALEQQVEEMKTQLEEL 966
>BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein.
Length = 691
Score = 55.2 bits (127), Expect = 5e-07
Identities = 70/409 (17%), Positives = 161/409 (39%), Gaps = 28/409 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQF 86
S RL + ++ QD L++E+ R + E DLS ++ + + L++ +
Sbjct: 287 SLTMRLHETLKQCQD-LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E + K E L+ + LE + + L++KN+ + Q ++ QL + ++ +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL----QGKLSQLEEHLSQLQDNP 401
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + EV + Q+E + +E T++ +L+ + L E + + + +
Sbjct: 402 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFE 458
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXX--ASLHQVE 262
+E +L + DL+ +I N+ K ++ ASQ A++ Q +
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 518
Query: 263 IDLESVRVQ-----------LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L ++ Q L+++ +A L Q+ + + + +
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ + A + +E + +++E+L L+ AN Q
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
Q +R E+ ++EE E +++ Q ++ + +L ++ +QK
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQL-RSEQQK 686
Score = 33.1 bits (72), Expect = 2.4
Identities = 21/90 (23%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 344 SRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQ 403
+RL ++V L +L N T ++ + L++ E +++L +T+Q EQ + LR+
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH-- 551
Query: 404 TELQRVSHELDKTREQKDALARENKKMGDD 433
+++++S L + +Q +A + + D
Sbjct: 552 -QVEQLSSSLKQKEQQLKEVAEKQEATRQD 580
>BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for
IMAGE:4540541) protein.
Length = 691
Score = 55.2 bits (127), Expect = 5e-07
Identities = 70/409 (17%), Positives = 161/409 (39%), Gaps = 28/409 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQF 86
S RL + ++ QD L++E+ R + E DLS ++ + + L++ +
Sbjct: 287 SLTMRLHETLKQCQD-LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
E + K E L+ + LE + + L++KN+ + Q ++ QL + ++ +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL----QGKLSQLEEHLSQLQDNP 401
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ + EV + Q+E + +E T++ +L+ + L E + + + +
Sbjct: 402 PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLET---ERGQQEAKLLAERGHFE 458
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXX--ASLHQVE 262
+E +L + DL+ +I N+ K ++ ASQ A++ Q +
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 518
Query: 263 IDLESVRVQ-----------LEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L ++ Q L+++ +A L Q+ + + + +
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ + A + +E + +++E+L L+ AN Q
Sbjct: 579 QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
Q +R E+ ++EE E +++ Q ++ + +L ++ +QK
Sbjct: 639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQL-RSEQQK 686
Score = 33.1 bits (72), Expect = 2.4
Identities = 21/90 (23%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 344 SRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQ 403
+RL ++V L +L N T ++ + L++ E +++L +T+Q EQ + LR+
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRH-- 551
Query: 404 TELQRVSHELDKTREQKDALARENKKMGDD 433
+++++S L + +Q +A + + D
Sbjct: 552 -QVEQLSSSLKQKEQQLKEVAEKQEATRQD 580
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/402 (19%), Positives = 159/402 (39%), Gaps = 27/402 (6%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDTELLKLRKLLEDV 106
E E + +++ + L QV QL+E+L+ ++E ++Q ++ + + LR + V
Sbjct: 557 EGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 107 HLESEETAHLLKKK---NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
L E + + L + ++E V QI T+ AE K+ +A++ L +N
Sbjct: 617 -LSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 164 TKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQR---LSQENIELVKEVQDL 219
++K ++K +L+ ++L K E ++ + +K++ L Q+ EL +++ L
Sbjct: 676 LQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 220 KVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR 279
+ + V K Q L + + S R+ L+++SEA
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 280 LDLERQLVKANGEIGHWRSKFXXXXXXXXX----------XXXXXXXKYSXXXXXXXXXX 329
++++L K E + F K
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTEL 855
Query: 330 XTLIAKINNVEKQKSRLQSEVE-------VLIIDLEKA-NGTARELQKRTEQLERVNIEI 381
T+ K++ V +SE E I+DLEK +LQ + E + E+
Sbjct: 856 STVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKEL 915
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
K LE+ + Q + +L + Q +L + + L + +++ L
Sbjct: 916 KKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957
Score = 52.4 bits (120), Expect = 4e-06
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 17/197 (8%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
V +E A ++ LS ++DK+ + D L++ + E+E ++ L + +E +
Sbjct: 844 VKMEKEALMTELSTVKDKLSKVSDSLKNSKS---EFEKENQKGKAAILDLEKTCKELKHQ 900
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ Q E K EL +K LE + +E +H LK + + QEQ+ Q T +
Sbjct: 901 LQVQMENTLKEQKEL---KKSLE----KEKEASHQLKLELNSM----QEQLIQAQNTLKQ 949
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI-EELNRTIVDITS 200
EKE+ + Q + EL E K+ + + + +EL K+ ++L + ++ +
Sbjct: 950 NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAA 1009
Query: 201 HKQRLS--QENIELVKE 215
K+++S Q N E +E
Sbjct: 1010 EKEKISVLQNNYEKSQE 1026
Score = 48.4 bits (110), Expect = 6e-05
Identities = 80/423 (18%), Positives = 176/423 (41%), Gaps = 33/423 (7%)
Query: 19 TTDVNIEYSADL--SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
T + NI+ DL ++L +I I+ + ER LR+ E++ L+ ++ + + ++
Sbjct: 149 TENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQ 208
Query: 77 EAEGGAESQ--FEINRKRDTELLKLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQ 131
+ + + E EL++++ L++++ LE E + LK KK Q +
Sbjct: 209 DLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEAT 268
Query: 132 IDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL 191
I QL A+ +E + + E+ +L + V +T++ T+++ + E + + K+EE
Sbjct: 269 ISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKE----QDYTKLEEK 324
Query: 192 NRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXX 251
+ +++ +S++NI+ +DL + + + S +
Sbjct: 325 H--------NEESVSKKNIQATLHQKDL--DCQQLQSRLSASETSLHRIHVELSEKGEAT 374
Query: 252 XXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
L +VE + ++ + ++ + R + E+ ++ EI SK
Sbjct: 375 QKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAH 434
Query: 312 XXXXXKY---SXXXXXXXXXXXTLIAKINNVEKQ-KSRLQSEVEVLIIDLEKANGTAREL 367
+ S L K++ +E+Q K ++ + E L L+K
Sbjct: 435 GRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTE-LQHQLDKTK------ 487
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
Q+ EQ + + ++L E EQ R + +K ++Q + L K++E L +E
Sbjct: 488 QQHQEQ-QALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 428 KKM 430
+ +
Sbjct: 547 EDL 549
Score = 47.2 bits (107), Expect = 1e-04
Identities = 83/430 (19%), Positives = 175/430 (40%), Gaps = 29/430 (6%)
Query: 28 ADLSA-LSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSE--RLEEAEGGAE 83
ADL LSRLE++++ + + + EL+ ++++ K Q +Q S +L EA+ E
Sbjct: 456 ADLQLKLSRLEEQLK---EKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLE 512
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+D ++ L LL+ +S+E LL+K+ +++ Q + E
Sbjct: 513 QVLRQIGDKDQKIQNLEALLQ----KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE 568
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K + Q +V +L +++N ++ + ++ + H++ + +R + TS +
Sbjct: 569 KNHT-LQEQVTQLTEKLKNQSESHKQAQENLHD-QVQEQKAHLRAAQ-DRVLSLETSVNE 625
Query: 204 RLSQENIELVKEVQ-DLKVNIENVVYLKSQIA--SQXXXXXXXXXXXXXXXXXXXASLHQ 260
SQ N K Q D+++ + + L ++ A +Q L++
Sbjct: 626 LNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNK 685
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX----XX 316
+ L+ V +L+++ E LE L + + K
Sbjct: 686 ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKAS 745
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAREL-QKRTE 372
K ++ E K +L+ E E++ +DL+K + + QK T+
Sbjct: 746 KEQALQDLQQQRQLNTDLELRATELSK-QLEMEKEIVSSTRLDLQKKSEALESIKQKLTK 804
Query: 373 QLERVNI---EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
Q E I + ++ +ET +E+ ++ TELQ+V E + + + + K
Sbjct: 805 QEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSK 864
Query: 430 MGDDLHDARA 439
+ D L ++++
Sbjct: 865 VSDSLKNSKS 874
Score = 46.4 bits (105), Expect = 2e-04
Identities = 83/431 (19%), Positives = 175/431 (40%), Gaps = 29/431 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE---GGAESQFEIN 89
LS +E K + ++ + + ++ R+ E+ L ++ QL +L E E G A + +
Sbjct: 381 LSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQ 440
Query: 90 RKRDTE-LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ +E L+ + + D+ L+ LK+K V + E QL KTK + +++++
Sbjct: 441 RQLSSEKLMDKEQQVADLQLKLSRLEEQLKEK----VTNSTELQHQLDKTKQQHQEQQAL 496
Query: 149 FQ---AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
Q A++ E +E V ++ + + LE + + I L + D+ + K +
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYA-KIQA 555
Query: 206 SQENIELVKEVQDLKVNI-ENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH----- 259
+ ++ ++Q+ + E V L ++ +Q A L
Sbjct: 556 GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 260 --QVEIDLESVRVQLEEESEARLDLERQLVKANGEI----GHWRSKFXXXXXXXXXXXXX 313
+E + + QL E E L+ Q +KA E+ ++
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQ-IKAKTELLLSAEAAKTAQRADLQNHLDTAQN 674
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ AK+ + ++ S+L+S ++ EL+ + ++
Sbjct: 675 ALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKK 734
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ--RVSHELDKTREQKDALARENKKMG 431
LE ++E+K+ E+ +Q +Q QR L N EL+ +S +L+ +E + + +K
Sbjct: 735 LEADSLEVKASKEQALQDLQQ-QRQL-NTDLELRATELSKQLEMEKEIVSSTRLDLQKKS 792
Query: 432 DDLHDARANIT 442
+ L + +T
Sbjct: 793 EALESIKQKLT 803
Score = 46.4 bits (105), Expect = 2e-04
Identities = 67/395 (16%), Positives = 160/395 (40%), Gaps = 17/395 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEINRKRDTELLKLRKL 102
Q L SE+ + + E++ ADL +++ +L E+L+E E Q ++++ + + + L
Sbjct: 440 QRQLSSEKLMDK--EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ-EQQAL 496
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
+ + E + L++ ++I D ++I L ++++ S + E +L A+++
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIG-DKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQA 555
Query: 163 VTKEKITISKTCER---LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
E +++ E+ L+ +++L K++ + + + QE ++ QD
Sbjct: 556 GEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 220 KVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
+++E V L SQ+ ++ ++ L+ A
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D +++L K ++ +K +Y L +I
Sbjct: 676 LQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLK-EYKEKYLSLEQKTEELEGQIKK 734
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRD 398
+E +++ E + DL++ +L+ R +L + +LE ++ T+ D
Sbjct: 735 LEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSK-------QLEMEKEIVSSTRLD 787
Query: 399 LRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
L+ K L+ + +L K E+K L ++ + + +
Sbjct: 788 LQKKSEALESIKQKLTKQEEEKQILKQDFETLSQE 822
Score = 46.0 bits (104), Expect = 3e-04
Identities = 48/195 (24%), Positives = 91/195 (46%), Gaps = 9/195 (4%)
Query: 30 LSALSRLED-KIRLIQDDLESERE---LRQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
+ ++ L+D K LIQ LE + + L+ +E+EK + + Q+ + EE + +
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELK---KEF 1211
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
E K +E+ K +++ H E+E + E + +++ + + EK+
Sbjct: 1212 IEKEAKLHSEI-KEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
+ E+ L A V+N E+ + + C + E I +L K+ EL R + + T+ Q L
Sbjct: 1271 TDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDNTTAAVQEL 1330
Query: 206 SQENIEL-VKEVQDL 219
+EN L +K Q L
Sbjct: 1331 GRENQSLQIKHTQAL 1345
Score = 44.0 bits (99), Expect = 0.001
Identities = 72/402 (17%), Positives = 154/402 (38%), Gaps = 17/402 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L+ ++K+ + ++++ EL E K + Q L L+ A+ + + +
Sbjct: 628 SQLNESKEKVSQLDIQIKAKTELLLSAEAAK---TAQRADLQNHLDTAQNALQDKQQELN 684
Query: 91 KRDTELLKLRKLLEDVHLE-SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K T+L ++ L+D S+ +HL K+ +E + +++ ++L E + K
Sbjct: 685 KITTQLDQVTAKLQDKQEHCSQLESHL--KEYKEKYLSLEQKTEEL-------EGQIKKL 735
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+A+ E+ A E ++ + LE+ +EL ++E + + IV T + E
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLE-MEKEIVSSTRLDLQKKSEA 794
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+E +K Q L E LK + L +V+++ E++
Sbjct: 795 LESIK--QKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+L + + L + E K +
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQ 912
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
L + ++ +L+ E+ + L +A T ++ +K +QL+ E+K E+
Sbjct: 913 KELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKK 972
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQ-KDALARENKKM 430
+ E Q +L+ + + ++L + Q LA E +K+
Sbjct: 973 KQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Score = 42.7 bits (96), Expect = 0.003
Identities = 75/390 (19%), Positives = 151/390 (38%), Gaps = 22/390 (5%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
++L+ E E Q +++++A V S L+ E Q E + + + +++ L E
Sbjct: 107 EELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLE----QQLEEAQTENFNIKQMKDLFE 162
Query: 105 DVHLE-SEETAHLLKKKNQEIVIDFQEQIDQ-LTKTKARAEKEKSKFQAEVYELLAQ--V 160
+ + E A + K ++E + +E +Q +T+ KE + Q ELL + +
Sbjct: 163 QKAAQLATEIADIKSKYDEERSL--REAAEQKVTRLTEELNKEATVIQDLKTELLQRPGI 220
Query: 161 ENVT---KEKITISKTCERLEITISELHIKI-EELNRTIVDITSHKQRLSQENIELVKEV 216
E+V KE + + + + + K+ +E + S + +SQ EL K
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGP 280
Query: 217 QDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXXASLHQVE-IDLESVRVQLE 273
Q++ V ++ + LKS + +Q H E + ++++ L
Sbjct: 281 QEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLH 340
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
++ L+ +L + + H + L
Sbjct: 341 QKDLDCQQLQSRLSASETSL-HRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQ 399
Query: 334 AKINNVEKQKSRLQSEVEVL---IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
+ E+ +LQSE+ L +++ E+ G A K QL + K + +Q
Sbjct: 400 QQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQ 459
Query: 391 L-YEQTQRDLRNKQTELQRVSHELDKTREQ 419
L + + L+ K T + H+LDKT++Q
Sbjct: 460 LKLSRLEEQLKEKVTNSTELQHQLDKTKQQ 489
Score = 39.9 bits (89), Expect = 0.021
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 12/196 (6%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK 98
K L QD + E++L++R + + + ++ E + E AE + EI +++ E+ K
Sbjct: 1084 KATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE-EIKCRQEKEITK 1142
Query: 99 LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA 158
L + L+ LES + LK Q ++ E + KA E+EK Q ++
Sbjct: 1143 LNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKK 1202
Query: 159 QVENVTKEKI----TISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQ 207
+ E + KE I + + E+ + ++L ++I LN + + Q +
Sbjct: 1203 EEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR 1262
Query: 208 ENIELVKEVQDLKVNI 223
EL K+ DL+ I
Sbjct: 1263 RVSELEKQTDDLRGEI 1278
Score = 36.3 bits (80), Expect = 0.26
Identities = 43/213 (20%), Positives = 90/213 (42%), Gaps = 11/213 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESER-------ELRQRIEREKADLSVQVIQLSERLEE 77
E A L +E+K+ L Q+DL S R +L Q ++ KA L + ++L+E
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ + ++ EL+ + L ++ + K N+E+ E I ++T
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 138 TKARAE---KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNR 193
K + ++K + Q + L A VE + + + ++ E + + I+ E +L+
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS 1220
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
I + ++ + +L ++ L N+ V
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITALNENLGTV 1253
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 54.0 bits (124), Expect = 1e-06
Identities = 65/275 (23%), Positives = 111/275 (40%), Gaps = 16/275 (5%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE-G 80
+ IE + +LEDKI+ I L S R + RE+ L+V+ Q+ E E +
Sbjct: 297 LQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLE 356
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESE-ETAHLLKKKNQEIV-IDFQEQIDQLT-- 136
++ Q ++ DT K R L + +E L EI+ + Q + L
Sbjct: 357 CSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAED 416
Query: 137 --KTKAR---AEKEKSKFQAEVYELLAQVENVTKEKITISKTCER---LEITISELHIKI 188
K K R EKEKS E EL + + E I T R L+ + +L + +
Sbjct: 417 NLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNL 476
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E + + S K+ L E EL ++ Q+ ++++ +K Q++ Q
Sbjct: 477 EAKEQELNQSISEKETLIAEIEELDRQNQEA---TKHMILIKDQLSKQQNEGDSIISKLK 533
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLE 283
+HQ+E D + +L+ + E + E
Sbjct: 534 QDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSE 568
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/198 (20%), Positives = 93/198 (46%), Gaps = 16/198 (8%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK 98
K+++ + LE E+ L + +EK +L + +++L+ E + A ++ + L
Sbjct: 419 KLKMRIEVLEKEKSL---LSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLN 475
Query: 99 LRKLLEDVHLESEETAHL------LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L ++++ E L L ++NQE DQL+K + + SK + +
Sbjct: 476 LEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQD 535
Query: 153 VYELLAQVENVTKEKITISKTC----ERL---EITISELHIKIEELNRTIVDITSHKQRL 205
+ + +V + +K+ I+K E+L E+ +++LH+ ++L + ++ +
Sbjct: 536 LNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKS 595
Query: 206 SQENIELVKEVQDLKVNI 223
+ N+ + KE +LK +I
Sbjct: 596 QESNVSIQKENLELKEHI 613
Score = 43.2 bits (97), Expect = 0.002
Identities = 66/418 (15%), Positives = 177/418 (42%), Gaps = 31/418 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQ--VIQLSERLEEAEGGAESQFEINR 90
++RL +++ ++ ++ R + Q + + D S Q + +L ++E + + + ++
Sbjct: 174 INRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQ 233
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+L++ H ++ + ++++E + D++E+I++L + +
Sbjct: 234 HE-------MSVLQNAH---QQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETD 283
Query: 151 -AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+++YE+ ++ + EK+ +K E+LE I +++ K+ + +++L+ E
Sbjct: 284 LSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEK 343
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
++++E ++LK+ + S + L Q D E+
Sbjct: 344 RQIMEECENLKLECSKL--QPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEI 401
Query: 270 VQLEEESEARLDLERQL-VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXX 328
++L ++ E L +K E+
Sbjct: 402 MRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATR 461
Query: 329 XXTLIAKIN----NVEKQKSRLQ---SEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
+L ++++ N+E ++ L SE E LI ++E+ + R+ Q+ T+ + + ++
Sbjct: 462 DISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELD---RQNQEATKHMILIKDQL 518
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHE-LDKTRE---QKDALARENKKMGDDLH 435
+ E + + ++DL +++ + ++ + +D T+E QK+ L + + +DLH
Sbjct: 519 SKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVAL-NDLH 575
Score = 40.3 bits (90), Expect = 0.016
Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 20/209 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL--------EEAEGGAESQF 86
+LEDK+ + D L +E I++E +L + Q E L + + S F
Sbjct: 580 KLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNF 639
Query: 87 E--INRKRDTELLKLRKLLEDVHLESE---ETAHLLKKKNQEIVI---DFQEQIDQLTKT 138
+ + ++R+ E+ L++ L ++ +E + A +K +N+++V+ D + Q+++
Sbjct: 640 KDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAG 699
Query: 139 KARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
+ EK+ + ++E + K + + + E TI EL LN + +
Sbjct: 700 NNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELS-NARNLNTSALQ 758
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + L + N + E+ +LK NIE +
Sbjct: 759 L--EHEHLIKLNQKKDMEIAELKKNIEQM 785
Score = 39.9 bits (89), Expect = 0.021
Identities = 77/419 (18%), Positives = 178/419 (42%), Gaps = 47/419 (11%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQ-LSERLEEAEGGAESQFEINR------- 90
++ I++ LE E + Q+I ++ +Q++Q L E+ +E + ++N
Sbjct: 900 QLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFL 959
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK-EKSKF 149
++D E+ L+K +E + + E ++ N +I FQE Q + +EK + SK
Sbjct: 960 EKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDI---FQETKVQSLNIENGSEKHDLSKA 1016
Query: 150 QAE-----VYELLAQVENVTKEKITISKTCERL------EIT--ISELHIKIEELNRTIV 196
+ E + E +++ + ++ I+++K ++L ++T I + ++I+ L+ I
Sbjct: 1017 ETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARIS 1076
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
TSH +Q+ + L +++Q + E V + ++ + A
Sbjct: 1077 S-TSH----TQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEA 1131
Query: 257 SLHQVEIDLESVRVQLEEES-----EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L +++ + + + + E E +L R + + + EI K
Sbjct: 1132 ALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSS 1191
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ L+ + + +++Q +++ + ++ ++ + +LQ+
Sbjct: 1192 TG-----NEAGGVNSHQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEEL 1246
Query: 372 EQLER---VNIEIKSRLEET----VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
QL+ V+ + S+L+ +Q YEQ + L+N EL +V H + + KD L
Sbjct: 1247 HQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLL 1305
Score = 37.9 bits (84), Expect = 0.084
Identities = 47/216 (21%), Positives = 103/216 (47%), Gaps = 23/216 (10%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQR---IEREKA-----DLSVQVIQLSERLEEAEGGAE 83
+L ++++ +Q++LE RE + R + K +L+ +V QL+ E E +
Sbjct: 854 SLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIK 913
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ---EIVIDFQEQIDQLTKT-- 138
+I ++ ++L + L++ E +E + ++ N ++ ++ E+I L KT
Sbjct: 914 HHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIE 973
Query: 139 --KARAEKEKSKFQAEVYELLAQVE----NVTK--EKITISKT-CERLEITISELHIKIE 189
K + +E+ Q + ++ + + N+ EK +SK ERL I E ++I+
Sbjct: 974 QIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIK 1033
Query: 190 ELNRTIVDITSHKQRLSQENI-ELVKEVQDLKVNIE 224
LN + +T +LS++ + +L + +Q + I+
Sbjct: 1034 LLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQ 1069
Score = 37.5 bits (83), Expect = 0.11
Identities = 32/201 (15%), Positives = 83/201 (41%), Gaps = 6/201 (2%)
Query: 83 ESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARA 142
E ++N+K+D E+ +L+K +E + + +ET +L +E Q+Q+ QL K
Sbjct: 762 EHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEE-----QKQLTQLINKKEIF 816
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
++ + +++ E L + ++ + +T E + ++ + + L + + +
Sbjct: 817 IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQ 876
Query: 203 QRLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
R + + + + V +L + + +K + + SL +
Sbjct: 877 SRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQ 936
Query: 262 EIDLESVRVQLEEESEARLDL 282
+ +++ R Q E+ + L
Sbjct: 937 KKEMDEFRYQHEQMNATHTQL 957
Score = 33.9 bits (74), Expect = 1.4
Identities = 64/387 (16%), Positives = 149/387 (38%), Gaps = 22/387 (5%)
Query: 42 LIQDDLESER-ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
LI+D L ++ E I + K DL+ + +R+ + E + + +I ++ D + KL
Sbjct: 513 LIKDQLSKQQNEGDSIISKLKQDLNDE----KKRVHQLE---DDKMDITKELDVQKEKL- 564
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV---YELL 157
+ +V L HL K+K ++ V + +Q+++ ++ +KE + + + E L
Sbjct: 565 -IQSEVALND---LHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEEL 620
Query: 158 AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQ 217
+++ N + + + + E ++ L + + ++ + L + ++ E +
Sbjct: 621 SRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENE 680
Query: 218 DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESE 277
L + E+V + Q+ ++E +L + +L EE+
Sbjct: 681 KLVLACEDV---RHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEAN 737
Query: 278 ARLDLERQLVKA---NGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
+L A N + K +++
Sbjct: 738 KYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLS 797
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+KQ ++L ++ E+ I L++ + +E + Q R N ++ +EE +
Sbjct: 798 SSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGS 857
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKD 421
+ + + Q EL+R+ E +T D
Sbjct: 858 MKEENNHLQEELERLREEQSRTAPVAD 884
Score = 32.7 bits (71), Expect = 3.2
Identities = 44/260 (16%), Positives = 104/260 (40%), Gaps = 4/260 (1%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSE-RLEEAEGGAESQFEINR 90
A++ L+++I +++ D+ + ++I + L E ++ + E +FE +
Sbjct: 1443 AVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHS 1502
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLK--KKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++ L + L E ++ E LL K QE + FQ++ DQ+ + + E +
Sbjct: 1503 MKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTA 1562
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI-VDITSHKQRLSQ 207
Q EV L + +E + E + + + E+ + +T +++L
Sbjct: 1563 LQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVS 1622
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
+ + V +E++ + ++ Q SL +++ LE
Sbjct: 1623 SSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEH 1682
Query: 268 VRVQLEEESEARLDLERQLV 287
+ + + A L+ ++QL+
Sbjct: 1683 FQQEEKAMYSAELEKQKQLI 1702
Score = 31.1 bits (67), Expect = 9.7
Identities = 27/125 (21%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 46 DLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
+LE +++L ++ +L +VI L E L+EA +S + + D + ++ +L
Sbjct: 1694 ELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQ 1753
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQ-LTKTKARAEKEKSKFQA-EVYELLAQVENV 163
L +E ++KK + + ++D+ L + K Q EV L+ + V
Sbjct: 1754 NELR-QEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGV 1812
Query: 164 TKEKI 168
+E++
Sbjct: 1813 RREEM 1817
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 53.6 bits (123), Expect = 2e-06
Identities = 77/404 (19%), Positives = 171/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 353 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 408
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 409 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 467
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E+ +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 468 TQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 527
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 528 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 587
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 588 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 636
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 637 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 689
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 690 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 733
Score = 46.0 bits (104), Expect = 3e-04
Identities = 78/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLES---ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+ ER ++E++ + +++L L+E + + + + + +
Sbjct: 458 KIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 517
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 518 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 577
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 578 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 630
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 631 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 674
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 675 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 730
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 731 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 787
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 788 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 821
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 511 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 570
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 571 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 630
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 631 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 687
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 688 DQVLEAKLEEVERLATELEKWKEK 711
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 637 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 696
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 697 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 756
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 757 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 814
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 815 REERDQLVAALEIQ-LKALISSNVQKDNEI 843
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 682 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 740
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 741 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 800
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 801 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 860
Query: 217 QDLK 220
D+K
Sbjct: 861 MDIK 864
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 53.6 bits (123), Expect = 2e-06
Identities = 77/404 (19%), Positives = 171/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 268 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKERE----HKNQDD 323
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 324 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 382
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E+ +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 383 TQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 442
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 443 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 502
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 503 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 551
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 552 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 604
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 605 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 648
Score = 43.6 bits (98), Expect = 0.002
Identities = 44/196 (22%), Positives = 90/196 (45%), Gaps = 16/196 (8%)
Query: 39 KIRLIQDDLES---ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+ ER ++E++ + +++L L+E + + + + + +
Sbjct: 373 KIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 432
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 433 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 492
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 493 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 545
Query: 210 IELVKEVQDLKVNIEN 225
+ +Q LK + N
Sbjct: 546 DMKQRTIQQLKEQLNN 561
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 426 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 485
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 486 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 545
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 546 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 602
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 603 DQVLEAKLEEVERLATELEKWKEK 626
Score = 31.1 bits (67), Expect = 9.7
Identities = 31/143 (21%), Positives = 69/143 (48%), Gaps = 15/143 (10%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 552 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 611
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 612 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 671
Query: 148 KFQAEVYELLAQ---VENVTKEK 167
K+ E L+ Q EN+ K+K
Sbjct: 672 KWLEEKMMLITQAKEAENIRKKK 694
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 53.6 bits (123), Expect = 2e-06
Identities = 77/404 (19%), Positives = 171/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 1057 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 1112
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 1113 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 1171
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E+ +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 1172 TQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1231
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 1232 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1291
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 1292 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 1340
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 1393
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 1394 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 1437
Score = 46.0 bits (104), Expect = 3e-04
Identities = 78/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLES---ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+ ER ++E++ + +++L L+E + + + + + +
Sbjct: 1162 KIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1221
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 1222 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 1334
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 1335 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 1378
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 1379 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 1434
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 1435 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 1491
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 1492 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 1525
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 1215 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1274
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 1275 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1334
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 1335 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 1391
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 1392 DQVLEAKLEEVERLATELEKWKEK 1415
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 1401 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1460
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 1461 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 1518
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 1519 REERDQLVAALEIQ-LKALISSNVQKDNEI 1547
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 1386 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 1444
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 1445 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 1504
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 1505 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 1564
Query: 217 QDLK 220
D+K
Sbjct: 1565 MDIK 1568
>BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix
protein p110 protein.
Length = 364
Score = 53.2 bits (122), Expect = 2e-06
Identities = 52/256 (20%), Positives = 120/256 (46%), Gaps = 13/256 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L++K+ +Q +L + ++ + L+ ++ +L+ E E + E K + +
Sbjct: 96 LKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQ 155
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +K E + + AH ++ ++ + +F +QI QL K + E K QAEV
Sbjct: 156 L---KKQAEQLFNQMYNPAHNIEDDSR-MNPEFADQIKQLDKEASYYRDECGKAQAEVDR 211
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
LL ++ V EK K I+EL +++ N+ + ++ ++Q ++N +L++E
Sbjct: 212 LLEILKEVENEKNDKDK-------KIAELERHMKDQNKKVANLKHNQQLEKKKNAQLLEE 264
Query: 216 VQDLKVNI-ENVVYLK-SQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
V+ + ++ +N +L+ ++ + SL + E L ++R++
Sbjct: 265 VRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERR 324
Query: 274 EESEARLDLERQLVKA 289
++ E L+++++ + A
Sbjct: 325 KQLEEILEMKQEALLA 340
Score = 34.3 bits (75), Expect = 1.0
Identities = 41/253 (16%), Positives = 105/253 (41%), Gaps = 7/253 (2%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
++D LE + ++++ +L Q+ ++L + +S + DT L L +
Sbjct: 1 MKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 60
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
L E E LK++ + + E+I+ K +++ + QAE+ E + + +
Sbjct: 61 LS----EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 116
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+ + +++ + + + L I IE+ + + + +L ++ +L ++ + N
Sbjct: 117 LKEHASSLASAGLKRDSKLKSLEIAIEQKKE---ECSKLEAQLKKQAEQLFNQMYNPAHN 173
Query: 223 IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDL 282
IE+ + + A Q A + ++ L+ V + ++ + +L
Sbjct: 174 IEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAEL 233
Query: 283 ERQLVKANGEIGH 295
ER + N ++ +
Sbjct: 234 ERHMKDQNKKVAN 246
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 53.2 bits (122), Expect = 2e-06
Identities = 63/218 (28%), Positives = 100/218 (45%), Gaps = 26/218 (11%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 807 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 866 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHL---QRINPTTVKMKSSVFDEDKT 922
Query: 149 FQAEVYE-----------LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E L+ ++E +EK+ +S+ L + + H +I LN +
Sbjct: 923 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 982
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+ K+++S EL E+ ENV +Q++S
Sbjct: 983 LKQEKEQVSLRCREL--EIIINHNRAENVQSCDTQVSS 1018
Score = 38.7 bits (86), Expect = 0.048
Identities = 57/270 (21%), Positives = 111/270 (41%), Gaps = 11/270 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 708 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 826
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI--TSHKQR 204
E +L Q E + K++ T S + E+ EL + L + D+ + +KQ
Sbjct: 827 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 886
Query: 205 LS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L + ++ + E L+ V +KS + + L +
Sbjct: 887 LEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME--- 943
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEI 293
LE + + E S+ DL QL + +GEI
Sbjct: 944 KLEVTKREKLELSQRLSDLSEQLKQKHGEI 973
Score = 37.9 bits (84), Expect = 0.084
Identities = 68/374 (18%), Positives = 151/374 (40%), Gaps = 24/374 (6%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + + K + E + +
Sbjct: 423 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME--NALRSYSN 480
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++ +
Sbjct: 481 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL-S 538
Query: 163 VTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
++E+I ++ T E ++E H + + +I S + + ++ EV + K+
Sbjct: 539 FSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 598
Query: 222 NIENVVYLKSQIASQXXXX--XXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEE-ESE 277
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 599 KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDN 658
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ ++Q+ E+ K + +K
Sbjct: 659 LGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 716 EMTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774
Query: 394 QTQRDLRNKQTELQ 407
L++++ L+
Sbjct: 775 AENSILKDEKKTLE 788
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 53.2 bits (122), Expect = 2e-06
Identities = 63/218 (28%), Positives = 100/218 (45%), Gaps = 26/218 (11%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 819 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 877
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 878 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHL---QRINPTTVKMKSSVFDEDKT 934
Query: 149 FQAEVYE-----------LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E L+ ++E +EK+ +S+ L + + H +I LN +
Sbjct: 935 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 994
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+ K+++S EL E+ ENV +Q++S
Sbjct: 995 LKQEKEQVSLRCREL--EIIINHNRAENVQSCDTQVSS 1030
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 2199 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 2255
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 2256 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 2315
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 2316 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 2375
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 2376 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 2432
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 2433 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 2489
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 2490 ENQTYFKSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2545
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 2546 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2605
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 2606 ED-ELGSDI 2613
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 3205 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 3264
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 3265 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLESEKVRIREMSSTLDRE 3323
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 3324 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 3380
Query: 213 VKEVQ 217
++++
Sbjct: 3381 RQQME 3385
Score = 38.7 bits (86), Expect = 0.048
Identities = 57/270 (21%), Positives = 111/270 (41%), Gaps = 11/270 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 720 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 779
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 780 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 838
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI--TSHKQR 204
E +L Q E + K++ T S + E+ EL + L + D+ + +KQ
Sbjct: 839 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 898
Query: 205 LS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L + ++ + E L+ V +KS + + L +
Sbjct: 899 LEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME--- 955
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEI 293
LE + + E S+ DL QL + +GEI
Sbjct: 956 KLEVTKREKLELSQRLSDLSEQLKQKHGEI 985
Score = 38.7 bits (86), Expect = 0.048
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 1957 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 2008
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 2009 ETEKLMKEKL--EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 2066
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 2067 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 2125
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 2126 LANHLKEKTD 2135
Score = 37.9 bits (84), Expect = 0.084
Identities = 68/374 (18%), Positives = 151/374 (40%), Gaps = 24/374 (6%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + + K + E + +
Sbjct: 435 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME--NALRSYSN 492
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++ +
Sbjct: 493 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL-S 550
Query: 163 VTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
++E+I ++ T E ++E H + + +I S + + ++ EV + K+
Sbjct: 551 FSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 610
Query: 222 NIENVVYLKSQIASQXXXX--XXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEE-ESE 277
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 611 KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDN 670
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ ++Q+ E+ K + +K
Sbjct: 671 LGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 727
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 728 EMTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 786
Query: 394 QTQRDLRNKQTELQ 407
L++++ L+
Sbjct: 787 AENSILKDEKKTLE 800
Score = 34.7 bits (76), Expect = 0.79
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 3134 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 3193
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E KK
Sbjct: 3194 EAFRLEVKDKTDEVHLLNDTLASEQKK 3220
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 2608 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 2664
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 2665 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 2722
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 2723 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2772
Score = 33.5 bits (73), Expect = 1.8
Identities = 57/342 (16%), Positives = 127/342 (37%), Gaps = 16/342 (4%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 1852 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 1911
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 1912 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRL 1971
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 1972 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAE- 2025
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 2026 KVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 2085
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 2086 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 2145
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
Q QRD++ + E++++ + + + A +K+ D H
Sbjct: 2146 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKH 2187
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 2194 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 2252
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 2253 TTRLQELEQE 2262
Score = 31.9 bits (69), Expect = 5.5
Identities = 55/316 (17%), Positives = 120/316 (37%), Gaps = 10/316 (3%)
Query: 118 KKKNQEIV-IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCE 175
+K +QE++ + Q++ Q+ + + K + E+ E L+ + V E K +++T
Sbjct: 3119 EKPSQELLEYNIQQKQSQMLEMQVELSSMKDR-ATELQEQLSSEKMVVAELKSELAQTKL 3177
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
LE T+ H ++EL +++ + N L E + + + K+++
Sbjct: 3178 ELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR 3237
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q+ + LE + QL ES+ +++ +R L A
Sbjct: 3238 SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK-QLLNESQQKIESQRMLYDAQLSEEQ 3296
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE--VEVL 353
R+ + + + + + L SE ++ L
Sbjct: 3297 GRN----LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3352
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 3353 QKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHEL 3412
Query: 414 DKTREQKDALARENKK 429
E E ++
Sbjct: 3413 QSKVEDLQRQLEEKRQ 3428
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 53.2 bits (122), Expect = 2e-06
Identities = 63/218 (28%), Positives = 100/218 (45%), Gaps = 26/218 (11%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 497 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 555
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 556 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHL---QRINPTTVKMKSSVFDEDKT 612
Query: 149 FQAEVYE-----------LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E L+ ++E +EK+ +S+ L + + H +I LN +
Sbjct: 613 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 672
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+ K+++S EL E+ ENV +Q++S
Sbjct: 673 LKQEKEQVSLRCREL--EIIINHNRAENVQSCDTQVSS 708
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 1875 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 1931
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 1932 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 1991
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 1992 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 2051
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 2052 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 2108
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 2109 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 2165
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 2166 ENQTYFKSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2221
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 2222 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2281
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 2282 ED-ELGSDI 2289
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 2889 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 2948
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 2949 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLESEKVRIREMSSTLDRE 3007
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 3008 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 3064
Query: 213 VKEVQ 217
++++
Sbjct: 3065 RQQME 3069
Score = 38.7 bits (86), Expect = 0.048
Identities = 57/270 (21%), Positives = 111/270 (41%), Gaps = 11/270 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 398 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 457
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 458 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 516
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI--TSHKQR 204
E +L Q E + K++ T S + E+ EL + L + D+ + +KQ
Sbjct: 517 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 576
Query: 205 LS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L + ++ + E L+ V +KS + + L +
Sbjct: 577 LEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME--- 633
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEI 293
LE + + E S+ DL QL + +GEI
Sbjct: 634 KLEVTKREKLELSQRLSDLSEQLKQKHGEI 663
Score = 38.3 bits (85), Expect = 0.064
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 1633 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 1684
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 1685 ETEKLMKEKL--EVQCQAEKDRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 1742
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 1743 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 1801
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 1802 LANHLKEKTD 1811
Score = 37.9 bits (84), Expect = 0.084
Identities = 68/374 (18%), Positives = 151/374 (40%), Gaps = 24/374 (6%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + + K + E + +
Sbjct: 113 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME--NALRSYSN 170
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++ +
Sbjct: 171 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL-S 228
Query: 163 VTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
++E+I ++ T E ++E H + + +I S + + ++ EV + K+
Sbjct: 229 FSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 288
Query: 222 NIENVVYLKSQIASQXXXX--XXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEE-ESE 277
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 289 KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDN 348
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ ++Q+ E+ K + +K
Sbjct: 349 LGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 405
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 406 EMTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 464
Query: 394 QTQRDLRNKQTELQ 407
L++++ L+
Sbjct: 465 AENSILKDEKKTLE 478
Score = 34.7 bits (76), Expect = 0.79
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 2818 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 2877
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E KK
Sbjct: 2878 EAFRLEVKDKTDEVHLLNDTLASEQKK 2904
Score = 33.9 bits (74), Expect = 1.4
Identities = 57/342 (16%), Positives = 127/342 (37%), Gaps = 16/342 (4%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 1528 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 1587
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 1588 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRL 1647
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 1648 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAEK 1702
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 1703 D-RDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 1761
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 1762 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 1821
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
Q QRD++ + E++++ + + + A +K+ D H
Sbjct: 1822 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKH 1863
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 2284 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 2340
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 2341 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 2398
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 2399 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2448
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 1870 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 1928
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 1929 TTRLQELEQE 1938
Score = 31.9 bits (69), Expect = 5.5
Identities = 55/316 (17%), Positives = 120/316 (37%), Gaps = 10/316 (3%)
Query: 118 KKKNQEIV-IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCE 175
+K +QE++ + Q++ Q+ + + K + E+ E L+ + V E K +++T
Sbjct: 2803 EKPSQELLEYNIQQKQSQMLEMQVELSSMKDR-ATELQEQLSSEKMVVAELKSELAQTKL 2861
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
LE T+ H ++EL +++ + N L E + + + K+++
Sbjct: 2862 ELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR 2921
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q+ + LE + QL ES+ +++ +R L A
Sbjct: 2922 SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK-QLLNESQQKIESQRMLYDAQLSEEQ 2980
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE--VEVL 353
R+ + + + + + L SE ++ L
Sbjct: 2981 GRN----LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3036
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 3037 QKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHEL 3096
Query: 414 DKTREQKDALARENKK 429
E E ++
Sbjct: 3097 QSKVEDLQRQLEEKRQ 3112
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 53.2 bits (122), Expect = 2e-06
Identities = 63/218 (28%), Positives = 100/218 (45%), Gaps = 26/218 (11%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 788 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 846
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 847 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHL---QRINPTTVKMKSSVFDEDKT 903
Query: 149 FQAEVYE-----------LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E L+ ++E +EK+ +S+ L + + H +I LN +
Sbjct: 904 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 963
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+ K+++S EL E+ ENV +Q++S
Sbjct: 964 LKQEKEQVSLRCREL--EIIINHNRAENVQSCDTQVSS 999
Score = 38.7 bits (86), Expect = 0.048
Identities = 57/270 (21%), Positives = 111/270 (41%), Gaps = 11/270 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 689 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 748
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 749 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 807
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI--TSHKQR 204
E +L Q E + K++ T S + E+ EL + L + D+ + +KQ
Sbjct: 808 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 867
Query: 205 LS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L + ++ + E L+ V +KS + + L +
Sbjct: 868 LEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME--- 924
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEI 293
LE + + E S+ DL QL + +GEI
Sbjct: 925 KLEVTKREKLELSQRLSDLSEQLKQKHGEI 954
Score = 37.9 bits (84), Expect = 0.084
Identities = 68/374 (18%), Positives = 151/374 (40%), Gaps = 24/374 (6%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + + K + E + +
Sbjct: 404 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME--NALRSYSN 461
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++ +
Sbjct: 462 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL-S 519
Query: 163 VTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
++E+I ++ T E ++E H + + +I S + + ++ EV + K+
Sbjct: 520 FSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 579
Query: 222 NIENVVYLKSQIASQXXXX--XXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEE-ESE 277
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 580 KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDN 639
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ ++Q+ E+ K + +K
Sbjct: 640 LGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 696
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 697 EMTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 755
Query: 394 QTQRDLRNKQTELQ 407
L++++ L+
Sbjct: 756 AENSILKDEKKTLE 769
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 52.8 bits (121), Expect = 3e-06
Identities = 82/434 (18%), Positives = 177/434 (40%), Gaps = 35/434 (8%)
Query: 24 IEYSADLSALSRLEDKIR---LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+E L+ L E K++ ++Q + ++ + +++ L + +
Sbjct: 680 VEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSE 739
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQLTKT 138
G ++ ++ + +++ L + + ES + + + ++ + +E+ + + QE + ++++
Sbjct: 740 GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQV 799
Query: 139 KARAEKE----KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
K EKE K KF AE E V+ +E T++K ++ E + L +E+L
Sbjct: 800 KETLEKELQILKEKF-AEASEEAVSVQRSMQE--TVNKLHQKEE-QFNMLSSDLEKLREN 855
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX----- 249
+ D+ + + + +L+K + L+ +I ++ + +SQ
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 915
Query: 250 ----XXXXXXASLHQVEIDLESVRVQLEEES------EARLDLERQLVKANGEIGHWRSK 299
AS Q I+ +V+ + ++ E + +LER+L ++ ++
Sbjct: 916 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 975
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K+ K+ ++ S L E+E L EK
Sbjct: 976 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 1035
Query: 360 ANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQTELQRVSHELDKT 416
A TA + + EQ+ + E + LE+T Q + Q +L K+ L+ V EL+K+
Sbjct: 1036 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV-EELNKS 1094
Query: 417 REQKDALARENKKM 430
K+ L EN+KM
Sbjct: 1095 ---KELLTVENQKM 1105
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/395 (18%), Positives = 153/395 (38%), Gaps = 19/395 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 896 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 954
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 955 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1014
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 1015 AREENSGLLQELEELRKQ-AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 1069
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 1070 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1129
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 1130 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 1186 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 1241
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ ++ +R L + + E ++ +E +
Sbjct: 1242 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ 1276
Score = 41.9 bits (94), Expect = 0.005
Identities = 53/244 (21%), Positives = 104/244 (42%), Gaps = 13/244 (5%)
Query: 46 DLESEREL-RQRIEREKADLSVQVIQLSERLEEAEGGAE---SQFEINRKRDTELLKLRK 101
++E E L R ++ +L ++ QL +E A+ +Q E KR E L+ R
Sbjct: 387 EIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLE-EEKRKVEDLQFRV 445
Query: 102 LLEDVHLESEETAHLLKKKN-QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
E + E A + +K E+ D ++ ++ + + R E K ++ L Q
Sbjct: 446 EEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE 505
Query: 161 ENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ +EK+ +++T + EIT + H + E + I + + ++LS+EN L +++
Sbjct: 506 ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 565
Query: 219 L-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
K N + + KS+ IAS A +++ +E +R+ +
Sbjct: 566 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQ 625
Query: 274 EESE 277
E E
Sbjct: 626 HEIE 629
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/180 (22%), Positives = 91/180 (50%), Gaps = 8/180 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIE--REKADLSVQVIQLSERLEEAEG---GAESQFEI 88
++ E++++ LE+E E+ Q+ R+ L ++ QL ++LE+ + E + E
Sbjct: 81 AKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK 140
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKE 145
+K + +L + E+ + + LKKKN+++ +ID+Q+QID +T E
Sbjct: 141 EKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGE 200
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
S +++++ + ++ E T+++ E++E+ E+ +EE + + +T R+
Sbjct: 201 DSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/400 (18%), Positives = 157/400 (39%), Gaps = 39/400 (9%)
Query: 56 RIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE---------DV 106
RI + + Q ++L+ LEE E E Q + + T+++KL LE D
Sbjct: 53 RITQSLMKMKAQEVELA--LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDT 110
Query: 107 HLESEETAHL---LKKKNQEIVIDFQEQI-------DQLTKTKARAEKEKSKFQAEVYEL 156
E L L++K++E+ D ++++ +QL AE E SK + E L
Sbjct: 111 RFLRNEICQLEKQLEQKDRELE-DMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRL 169
Query: 157 LAQVENVTKEKITISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E + ++ I K + + T+ S+ ++ + N ++ Q L++ N
Sbjct: 170 KKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEAN 229
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
++ + Q+++ N+E V ++ + ++ ++ +
Sbjct: 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
L+ ++E + + +V N ++ W+ +
Sbjct: 290 DLLKSKNE---EDDPIMVAVNAKVEEWK------LILSSKDDEIIEYQQMLHNLREKLKN 340
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
L A +NV + +Q + + E+ +E++K T +E + E++ R +
Sbjct: 341 AQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQ-RNKGAS 399
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
L +QT +++ L+ + E ++T E +A ARE K
Sbjct: 400 TLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
Score = 40.7 bits (91), Expect = 0.012
Identities = 57/275 (20%), Positives = 122/275 (44%), Gaps = 18/275 (6%)
Query: 29 DLSALSRLEDKIRL-IQDDLESERELRQRIERE-KADLSVQVIQLSERLEEAEGGAESQF 86
++ L++ +K+ L I D L+ LR+R+ E K + + + S+ L++ + AE+Q
Sbjct: 478 EIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQI 537
Query: 87 EINR--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDFQEQIDQLTKTKARAE 143
+ + E L L+K + + E + + +++ + + Q D++++ K
Sbjct: 538 LLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLL 597
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ +A+ ++ E +++E I + ER I++ K++EL V+ +
Sbjct: 598 SLKNMSEAQ-----SKNEFLSRELIEKERDLERSRTVIAKFQNKLKEL----VEENKQLE 648
Query: 204 RLSQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+E ++ +KE+Q D+K E + + S A + Q
Sbjct: 649 EGMKEILQAIKEMQKDPDVKGG-ETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQ 707
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
+ E +R +L E + ++ +QL KAN +I H
Sbjct: 708 LTGRNEELRQELRESRKEAINYSQQLAKANLKIDH 742
Score = 38.7 bits (86), Expect = 0.048
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 20/196 (10%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+LS L K++ + DLE +RE+ + +E ++ +QL E E+ +++ E
Sbjct: 1636 SLSSLLVKLKKVSQDLERQREITELKVKEFENIK---LQLQENHEDEVKKVKAEVE---- 1688
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDFQEQIDQLTKTKARAEKEKSKFQ 150
D + L + E L+SE A K+ N + +++L A EK++
Sbjct: 1689 -DLKYLLDQSQKESQCLKSELQAQ--KEANSRAPTTTMRNLVERLKSQLALKEKQQKALS 1745
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL-NRTIVDITSHKQRLSQEN 209
+ EL A++ +E+I IS T ++ E H+ ++++ +R ++ + + L+ EN
Sbjct: 1746 RALLELRAEMTAAAEERI-ISATSQK------EAHLNVQQIVDRHTRELKTQVEDLN-EN 1797
Query: 210 IELVKEVQDLKVNIEN 225
+ +KE N EN
Sbjct: 1798 LLKLKEALKTSKNREN 1813
Score = 36.7 bits (81), Expect = 0.19
Identities = 38/189 (20%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK--LRKLLED 105
E+ + ++++ E DL + Q + + + ++Q E N + T ++ + +L
Sbjct: 1674 ENHEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQ 1733
Query: 106 VHLESEETAHL---LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
+ L+ ++ L L + E+ +E+I T K + EL QVE+
Sbjct: 1734 LALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVED 1793
Query: 163 VT------KEKITISKTCER-LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+ KE + SK E L +++L+ ++++ + I K+ + QEN EL ++
Sbjct: 1794 LNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQ 1853
Query: 216 VQDLKVNIE 224
++ L ++
Sbjct: 1854 IKRLTSGLQ 1862
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/135 (18%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S LS+ ++ D++++ E ++IE + ++ + + + +E+ I
Sbjct: 206 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVH 265
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQE---IVIDFQEQIDQLTKTKARAEKEKS 147
+ D + +L+K + L+ +E LLK KN+E I++ ++++ + + E
Sbjct: 266 QTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII 325
Query: 148 KFQAEVYELLAQVEN 162
++Q ++ L +++N
Sbjct: 326 EYQQMLHNLREKLKN 340
Score = 35.9 bits (79), Expect = 0.34
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 20/219 (9%)
Query: 20 TDVNIE-YSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T +N++ + L D + D + +R L +E+ + +L V+V +L E + A
Sbjct: 1105 TKINLDAQKVEQMLRDELADSVSKAVSDADRQRILE--LEKNEMELKVEVSKLREISDIA 1162
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-----QID 133
E + RD E+ LR L D +S+E + + K + + E +++
Sbjct: 1163 RRQVEILNAQQQSRDKEVESLRMQLLDYQAQSDEKSLIAKLHQHNVSLQLSEATALGKLE 1222
Query: 134 QLTKTKARAEKEKSKFQAEVYE-----LLAQVENVTKEKITISKTCERLEITIS-ELHI- 186
+T + E + + ++ E A++E + K + +T + L S L +
Sbjct: 1223 SITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNRAK-HLRQTIQSLRRQFSGALPLA 1281
Query: 187 KIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+ E+ ++T++ + + K ++ QE +K Q N+EN
Sbjct: 1282 QQEKFSKTMIQLQNDKLKIMQE----MKNSQQEHRNMEN 1316
Score = 35.1 bits (77), Expect = 0.59
Identities = 73/361 (20%), Positives = 145/361 (40%), Gaps = 35/361 (9%)
Query: 71 LSERLEEAEGGAESQFEINRKRDTELLKLRKLLED----VHLESEETAHLLKKKNQEIVI 126
L E+ +EAE AE R++D EL++ K L+D V+ + + KNQ +
Sbjct: 416 LKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIR 475
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITIS-KTCERLEITISELH 185
D +I+ LT KE +K + ++ + L + E +E++ + KT L + H
Sbjct: 476 D--REIEILT-------KEINKLELKISDFLDENE-ALRERVGLEPKTMIDLTEFRNSKH 525
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXX 245
+K ++ + Q L +E L +E DLK I + + + ++
Sbjct: 526 LKQQQYR-------AENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLN 578
Query: 246 XXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXX 305
S + ++DL S++ E +S+ L R+L++ ++ RS+
Sbjct: 579 LTENISQGDRIS--ERKLDLLSLKNMSEAQSKNEF-LSRELIEKERDLE--RSRTVIAKF 633
Query: 306 XXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
K ++ I ++K E ++I LE+
Sbjct: 634 QNKLKELVEENK------QLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIE 687
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
K E + ++ +K+++++ E+ +++LR + E S +L K + D L +
Sbjct: 688 --SKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEK 745
Query: 426 E 426
E
Sbjct: 746 E 746
Score = 31.5 bits (68), Expect = 7.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+K+ EQ +R +++ LE+ ++ EQ LRN++ E +E K R + L +
Sbjct: 119 QLEKQLEQKDRELEDMEKELEKEKKVNEQLA--LRNEEAE-----NENSKLRRENKRLKK 171
Query: 426 ENKKMGDDLHDARANI 441
+N+++ D+ D + I
Sbjct: 172 KNEQLCQDIIDYQKQI 187
Score = 31.1 bits (67), Expect = 9.7
Identities = 40/213 (18%), Positives = 94/213 (44%), Gaps = 11/213 (5%)
Query: 18 GTTDVNIEYSADLSALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLE 76
G D ++ A + L+ +++R Q+ ES +E + + KA+L + ++ L
Sbjct: 693 GIFDASLHLKAQVDQLTGRNEELR--QELRESRKEAINYSQQLAKANLKIDHLEKETSLL 750
Query: 77 EAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQ 134
G+ F+ D ++ ++E HLL++ +N+E + + ++ ++
Sbjct: 751 RQSEGSNVVFKGIDLPDGIAPSSASIINS---QNEYLIHLLQELENKEKKLKNLEDSLED 807
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
+ A ++S E L++ E E TI + +LE + + IK++E N
Sbjct: 808 YNRKFAVIRHQQSLLYKEY---LSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEYNNL 864
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ + + + E +++ L+VN ++++
Sbjct: 865 LNALQMDSDEMKKILAENSRKITVLQVNEKSLI 897
>BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein.
Length = 805
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/180 (22%), Positives = 91/180 (50%), Gaps = 8/180 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIE--REKADLSVQVIQLSERLEEAEG---GAESQFEI 88
++ E++++ LE+E E+ Q+ R+ L ++ QL ++LE+ + E + E
Sbjct: 81 AKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK 140
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKE 145
+K + +L + E+ + + LKKKN+++ +ID+Q+QID +T E
Sbjct: 141 EKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGE 200
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
S +++++ + ++ E T+++ E++E+ E+ +EE + + +T R+
Sbjct: 201 DSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/400 (18%), Positives = 157/400 (39%), Gaps = 39/400 (9%)
Query: 56 RIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE---------DV 106
RI + + Q ++L+ LEE E E Q + + T+++KL LE D
Sbjct: 53 RITQSLMKMKAQEVELA--LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDT 110
Query: 107 HLESEETAHL---LKKKNQEIVIDFQEQI-------DQLTKTKARAEKEKSKFQAEVYEL 156
E L L++K++E+ D ++++ +QL AE E SK + E L
Sbjct: 111 RFLRNEICQLEKQLEQKDRELE-DMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRL 169
Query: 157 LAQVENVTKEKITISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E + ++ I K + + T+ S+ ++ + N ++ Q L++ N
Sbjct: 170 KKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEAN 229
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
++ + Q+++ N+E V ++ + ++ ++ +
Sbjct: 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
L+ ++E + + +V N ++ W+ +
Sbjct: 290 DLLKSKNE---EDDPIMVAVNAKVEEWK------LILSSKDDEIIEYQQMLHNLREKLKN 340
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
L A +NV + +Q + + E+ +E++K T +E + E++ R +
Sbjct: 341 AQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQ-RNKGAS 399
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
L +QT +++ L+ + E ++T E +A ARE K
Sbjct: 400 TLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
Score = 40.7 bits (91), Expect = 0.012
Identities = 57/275 (20%), Positives = 122/275 (44%), Gaps = 18/275 (6%)
Query: 29 DLSALSRLEDKIRL-IQDDLESERELRQRIERE-KADLSVQVIQLSERLEEAEGGAESQF 86
++ L++ +K+ L I D L+ LR+R+ E K + + + S+ L++ + AE+Q
Sbjct: 478 EIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQQQYRAENQI 537
Query: 87 EINR--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI-VIDFQEQIDQLTKTKARAE 143
+ + E L L+K + + E + + +++ + + Q D++++ K
Sbjct: 538 LLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLL 597
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ +A+ ++ E +++E I + ER I++ K++EL V+ +
Sbjct: 598 SLKNMSEAQ-----SKNEFLSRELIEKERDLERSRTVIAKFQNKLKEL----VEENKQLE 648
Query: 204 RLSQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
+E ++ +KE+Q D+K E + + S A + Q
Sbjct: 649 EGMKEILQAIKEMQKDPDVKGG-ETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQ 707
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
+ E +R +L E + ++ +QL KAN +I H
Sbjct: 708 LTGRNEELRQELRESRKEAINYSQQLAKANLKIDH 742
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/135 (18%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S LS+ ++ D++++ E ++IE + ++ + + + +E+ I
Sbjct: 206 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVH 265
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQE---IVIDFQEQIDQLTKTKARAEKEKS 147
+ D + +L+K + L+ +E LLK KN+E I++ ++++ + + E
Sbjct: 266 QTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII 325
Query: 148 KFQAEVYELLAQVEN 162
++Q ++ L +++N
Sbjct: 326 EYQQMLHNLREKLKN 340
Score = 35.1 bits (77), Expect = 0.59
Identities = 73/361 (20%), Positives = 145/361 (40%), Gaps = 35/361 (9%)
Query: 71 LSERLEEAEGGAESQFEINRKRDTELLKLRKLLED----VHLESEETAHLLKKKNQEIVI 126
L E+ +EAE AE R++D EL++ K L+D V+ + + KNQ +
Sbjct: 416 LKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIR 475
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITIS-KTCERLEITISELH 185
D +I+ LT KE +K + ++ + L + E +E++ + KT L + H
Sbjct: 476 D--REIEILT-------KEINKLELKISDFLDENE-ALRERVGLEPKTMIDLTEFRNSKH 525
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXX 245
+K ++ + Q L +E L +E DLK I + + + ++
Sbjct: 526 LKQQQYR-------AENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLN 578
Query: 246 XXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXX 305
S + ++DL S++ E +S+ L R+L++ ++ RS+
Sbjct: 579 LTENISQGDRIS--ERKLDLLSLKNMSEAQSKNEF-LSRELIEKERDLE--RSRTVIAKF 633
Query: 306 XXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
K ++ I ++K E ++I LE+
Sbjct: 634 QNKLKELVEENK------QLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIE 687
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
K E + ++ +K+++++ E+ +++LR + E S +L K + D L +
Sbjct: 688 --SKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEK 745
Query: 426 E 426
E
Sbjct: 746 E 746
Score = 31.5 bits (68), Expect = 7.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+K+ EQ +R +++ LE+ ++ EQ LRN++ E +E K R + L +
Sbjct: 119 QLEKQLEQKDRELEDMEKELEKEKKVNEQLA--LRNEEAE-----NENSKLRRENKRLKK 171
Query: 426 ENKKMGDDLHDARANI 441
+N+++ D+ D + I
Sbjct: 172 KNEQLCQDIIDYQKQI 187
>AK057222-1|BAB71385.1| 740|Homo sapiens protein ( Homo sapiens
cDNA FLJ32660 fis, clone TESTI1000051, weakly similar to
CYTADHERENCE HIGH MOLECULAR WEIGHT PROTEIN 2. ).
Length = 740
Score = 52.8 bits (121), Expect = 3e-06
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 9/204 (4%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF--EINRKRDTELL 97
IR I +E E RQRIE+ + ++ + E + E G + + E+ +T+ L
Sbjct: 103 IREIHRRVEEEEIKRQRIEKLENEVKTSQDKFDEITSKWEEGKQKRIPQELWEMLNTQQL 162
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE----KSKFQAEV 153
LLED + E LK K+ + V D ++Q D + R E++ F+ E+
Sbjct: 163 HCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFREEL 222
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQRLSQENIEL 212
Y + E +E + +K ++ E + + K +E LN + + ++++L+++ I
Sbjct: 223 YNIEKAFEVERQELLASNK--KKWEQALQAHNAKELEYLNNRMKKVEDYEKQLNRQRIWD 280
Query: 213 VKEVQDLKVNIENVVYLKSQIASQ 236
+E +K+ +E V + Q Q
Sbjct: 281 CEEYNMIKIKLEQDVQILEQQLQQ 304
>AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens
cDNA FLJ13615 fis, clone PLACE1010896, weakly similar to
NUF1 PROTEIN. ).
Length = 574
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/180 (22%), Positives = 91/180 (50%), Gaps = 8/180 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIE--REKADLSVQVIQLSERLEEAEG---GAESQFEI 88
++ E++++ LE+E E+ Q+ R+ L ++ QL ++LE+ + E + E
Sbjct: 81 AKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK 140
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKE 145
+K + +L + E+ + + LKKKN+++ +ID+Q+QID +T E
Sbjct: 141 EKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGE 200
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
S +++++ + ++ E T+++ E++E+ E+ +EE + + +T R+
Sbjct: 201 DSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 260
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/400 (18%), Positives = 157/400 (39%), Gaps = 39/400 (9%)
Query: 56 RIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE---------DV 106
RI + + Q ++L+ LEE E E Q + + T+++KL LE D
Sbjct: 53 RITQSLMKMKAQEVELA--LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDT 110
Query: 107 HLESEETAHL---LKKKNQEIVIDFQEQI-------DQLTKTKARAEKEKSKFQAEVYEL 156
E L L++K++E+ D ++++ +QL AE E SK + E L
Sbjct: 111 RFLRNEICQLEKQLEQKDRELE-DMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRL 169
Query: 157 LAQVENVTKEKITISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E + ++ I K + + T+ S+ ++ + N ++ Q L++ N
Sbjct: 170 KKKNEQLCQDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEAN 229
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
++ + Q+++ N+E V ++ + ++ ++ +
Sbjct: 230 EKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELT 289
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
L+ ++E + + +V N ++ W+ +
Sbjct: 290 DLLKSKNE---EDDPIMVAVNAKVEEWK------LILSSKDDEIIEYQQMLHNLREKLKN 340
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
L A +NV + +Q + + E+ +E++K T +E + E++ R +
Sbjct: 341 AQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQ-RNKGAS 399
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
L +QT +++ L+ + E ++T E +A ARE K
Sbjct: 400 TLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDK 439
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/135 (18%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S LS+ ++ D++++ E ++IE + ++ + + + +E+ I
Sbjct: 206 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVH 265
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQE---IVIDFQEQIDQLTKTKARAEKEKS 147
+ D + +L+K + L+ +E LLK KN+E I++ ++++ + + E
Sbjct: 266 QTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII 325
Query: 148 KFQAEVYELLAQVEN 162
++Q ++ L +++N
Sbjct: 326 EYQQMLHNLREKLKN 340
Score = 31.5 bits (68), Expect = 7.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+K+ EQ +R +++ LE+ ++ EQ LRN++ E +E K R + L +
Sbjct: 119 QLEKQLEQKDRELEDMEKELEKEKKVNEQLA--LRNEEAE-----NENSKLRRENKRLKK 171
Query: 426 ENKKMGDDLHDARANI 441
+N+++ D+ D + I
Sbjct: 172 KNEQLCQDIIDYQKQI 187
>AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H11
antigen protein.
Length = 589
Score = 52.8 bits (121), Expect = 3e-06
Identities = 40/180 (22%), Positives = 91/180 (50%), Gaps = 8/180 (4%)
Query: 34 SRLEDKIRLIQDDLESERELRQRIE--REKADLSVQVIQLSERLEEAEG---GAESQFEI 88
++ E++++ LE+E E+ Q+ R+ L ++ QL ++LE+ + E + E
Sbjct: 23 AKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEK 82
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKE 145
+K + +L + E+ + + LKKKN+++ +ID+Q+QID +T E
Sbjct: 83 EKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSRRGE 142
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
S +++++ + ++ E T+++ E++E+ E+ +EE + + +T R+
Sbjct: 143 DSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRM 202
Score = 41.5 bits (93), Expect = 0.007
Identities = 71/392 (18%), Positives = 154/392 (39%), Gaps = 39/392 (9%)
Query: 64 LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE---------DVHLESEETA 114
+ Q ++L+ LEE E E Q + + T+++KL LE D E
Sbjct: 3 MKAQEVELA--LEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEIC 60
Query: 115 HL---LKKKNQEIVIDFQEQI-------DQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
L L++K++E+ D ++++ +QL AE E SK + E L + E +
Sbjct: 61 QLEKQLEQKDRELE-DMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLC 119
Query: 165 KEKITISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQ 217
++ I K + + T+ S+ ++ + N ++ Q L++ N ++ + Q
Sbjct: 120 QDIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDEIQTLTEANEKIEVQNQ 179
Query: 218 DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESE 277
+++ N+E V ++ + ++ ++ + L+ ++E
Sbjct: 180 EMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKENDHYQLQVQELTDLLKSKNE 239
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ + +V N ++ W+ + L A +
Sbjct: 240 ---EDDPIMVAVNAKVEEWK------LILSSKDDEIIEYQQMLHNLREKLKNAQLDADKS 290
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
NV + +Q + + E+ +E++K T +E + E++ R + L +QT
Sbjct: 291 NVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQ-RNKGASTLSQQTHM 349
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKK 429
+++ L+ + E ++T E +A ARE K
Sbjct: 350 KIQSTLDILKEKTKEAERTAELAEADAREKDK 381
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/135 (18%), Positives = 65/135 (48%), Gaps = 3/135 (2%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S LS+ ++ D++++ E ++IE + ++ + + + +E+ I
Sbjct: 148 SQLSKKNYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVH 207
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQE---IVIDFQEQIDQLTKTKARAEKEKS 147
+ D + +L+K + L+ +E LLK KN+E I++ ++++ + + E
Sbjct: 208 QTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII 267
Query: 148 KFQAEVYELLAQVEN 162
++Q ++ L +++N
Sbjct: 268 EYQQMLHNLREKLKN 282
Score = 32.3 bits (70), Expect = 4.2
Identities = 39/153 (25%), Positives = 70/153 (45%), Gaps = 13/153 (8%)
Query: 71 LSERLEEAEGGAESQFEINRKRDTELLKLRKLLED----VHLESEETAHLLKKKNQEIVI 126
L E+ +EAE AE R++D EL++ K L+D V+ + + KNQ +
Sbjct: 358 LKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLEDAVVEIKNCKNQIKIR 417
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHI 186
D +I+ LTK + E + S F E L +V K I ++ E S+ H+
Sbjct: 418 D--REIEILTKEINKLELKISDFPDENEALRERVGLEPKTMIDLT------EFRNSK-HL 468
Query: 187 KIEELNRTIVDITSHKQRLSQENIELVKEVQDL 219
K ++ + + L +E ++L K+++ +
Sbjct: 469 KQQQYRAENQILLKEIESLEEERLDLKKKIRQM 501
Score = 31.5 bits (68), Expect = 7.3
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAR 425
+L+K+ EQ +R +++ LE+ ++ EQ LRN++ E +E K R + L +
Sbjct: 61 QLEKQLEQKDRELEDMEKELEKEKKVNEQLA--LRNEEAE-----NENSKLRRENKRLKK 113
Query: 426 ENKKMGDDLHDARANI 441
+N+++ D+ D + I
Sbjct: 114 KNEQLCQDIIDYQKQI 129
>AC093378-1|AAY15082.1| 659|Homo sapiens unknown protein.
Length = 659
Score = 52.8 bits (121), Expect = 3e-06
Identities = 49/204 (24%), Positives = 94/204 (46%), Gaps = 9/204 (4%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF--EINRKRDTELL 97
IR I +E E RQRIE+ + ++ + E + E G + + E+ +T+ L
Sbjct: 22 IREIHRRVEEEEIKRQRIEKLENEVKTSQDKFDEITSKWEEGKQKRIPQELWEMLNTQQL 81
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE----KSKFQAEV 153
LLED + E LK K+ + V D ++Q D + R E++ F+ E+
Sbjct: 82 HCAGLLEDKNKLISELQQELKTKDDQYVKDLKKQSDDICLLLERMEEQVKNVMKTFREEL 141
Query: 154 YELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQRLSQENIEL 212
Y + E +E + +K ++ E + + K +E LN + + ++++L+++ I
Sbjct: 142 YNIEKAFEVERQELLASNK--KKWEQALQAHNAKELEYLNNRMKKVEDYEKQLNRQRIWD 199
Query: 213 VKEVQDLKVNIENVVYLKSQIASQ 236
+E +K+ +E V + Q Q
Sbjct: 200 CEEYNMIKIKLEQDVQILEQQLQQ 223
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 52.4 bits (120), Expect = 4e-06
Identities = 74/386 (19%), Positives = 163/386 (42%), Gaps = 32/386 (8%)
Query: 65 SVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE 123
S Q+ +L +++E+ + + + E NR ++ E K +D+ E E LK++ QE
Sbjct: 8 SHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDDLLKEKETLIQQLKEELQE 63
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVENVTKEKITISKTCERL-- 177
+ QI + + K RA E ++ ++A++ EL +E E+ +K + +
Sbjct: 64 KNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILE 122
Query: 178 -EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQ 236
E I +L ++E + D + + L+ + ++L +E+ L N++++ +L +
Sbjct: 123 KESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEE 182
Query: 237 XXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHW 296
A ++ DL+ + E D ++Q+ + E+
Sbjct: 183 EETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVM 242
Query: 297 RSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE-VEVLII 355
R + K + L K +++ K +L ++ VE I
Sbjct: 243 RDE-----------DKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQ 291
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDK 415
E+A ++L + + +E +++ LEE Q + + L K E++R++ EL+K
Sbjct: 292 QYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEK 344
Query: 416 TREQKDALARENKKMGDDLHDARANI 441
+E+ + L +N + + H+ ++
Sbjct: 345 WKEKCNDLETKNNQRSNKEHENNTDV 370
Score = 46.0 bits (104), Expect = 3e-04
Identities = 78/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLES---ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+ ER ++E++ + +++L L+E + + + + + +
Sbjct: 95 KIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 154
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 155 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 214
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 215 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 267
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 268 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 311
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 312 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 367
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 368 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 424
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 425 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 458
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 148 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 207
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 208 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 267
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 268 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 324
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 325 DQVLEAKLEEVERLATELEKWKEK 348
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 274 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 333
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 334 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 393
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 394 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 451
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 452 REERDQLVAALEIQ-LKALISSNVQKDNEI 480
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 319 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 377
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 378 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 437
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 438 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 497
Query: 217 QDLK 220
D+K
Sbjct: 498 MDIK 501
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 52.4 bits (120), Expect = 4e-06
Identities = 48/197 (24%), Positives = 92/197 (46%), Gaps = 17/197 (8%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
V +E A ++ LS ++DK+ + D L++ + E+E ++ L + +E +
Sbjct: 844 VKMEKEALMTELSTVKDKLSKVSDSLKNSKS---EFEKENQKGKAAILDLEKTCKELKHQ 900
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ Q E K EL +K LE + +E +H LK + + QEQ+ Q T +
Sbjct: 901 LQVQMENTLKEQKEL---KKSLE----KEKEASHQLKLELNSM----QEQLIQAQNTLKQ 949
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI-EELNRTIVDITS 200
EKE+ + Q + EL E K+ + + + +EL K+ ++L + ++ +
Sbjct: 950 NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAA 1009
Query: 201 HKQRLS--QENIELVKE 215
K+++S Q N E +E
Sbjct: 1010 EKEKISVLQNNYEKSQE 1026
Score = 50.8 bits (116), Expect = 1e-05
Identities = 83/431 (19%), Positives = 173/431 (40%), Gaps = 31/431 (7%)
Query: 28 ADLSA-LSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSE--RLEEAEGGAE 83
ADL LSRLE++++ + + + EL+ ++++ K Q +Q S +L EA+ E
Sbjct: 456 ADLQLKLSRLEEQLK---EKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLE 512
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
++D ++ L LL+ +S+E LL+K+ +++ Q + E
Sbjct: 513 QVLRQIGEKDQKIQNLEALLQ----KSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE 568
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K + Q EV +L ENV + + + E L + E + ++ + +
Sbjct: 569 KNHT-LQDEVTQL---TENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVN 624
Query: 204 RLSQENIELVKEVQ--DLKVNIENVVYLKSQIA--SQXXXXXXXXXXXXXXXXXXXASLH 259
L+ + E ++V D+++ + + L ++ A +Q L+
Sbjct: 625 ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELN 684
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX----X 315
++ L+ V +L+++ E LE L + + K
Sbjct: 685 KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKA 744
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAREL-QKRT 371
K ++ E K +L+ E E++ +DL+K + + QK T
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSK-QLEMEKEIVSSTRLDLQKKSEALESIKQKLT 803
Query: 372 EQLERVNI---EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+Q E I + ++ +ET +E+ ++ TELQ+V E + + + +
Sbjct: 804 KQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLS 863
Query: 429 KMGDDLHDARA 439
K+ D L ++++
Sbjct: 864 KVSDSLKNSKS 874
Score = 50.8 bits (116), Expect = 1e-05
Identities = 77/402 (19%), Positives = 158/402 (39%), Gaps = 27/402 (6%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDTELLKLRKLLEDV 106
E E + +++ + L +V QL+E ++ ++E ++Q ++ + + LR + V
Sbjct: 557 EGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 107 HLESEETAHLLKKK---NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
L E + + L + ++E V QI T+ AE K+ +A++ L +N
Sbjct: 617 -LSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 164 TKEKIT-ISKTCERLEITISELHIKIEELNRTIVDITSHKQR---LSQENIELVKEVQDL 219
++K ++K +L+ ++L K E ++ + +K++ L Q+ EL +++ L
Sbjct: 676 LQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 220 KVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEAR 279
+ + V K Q L + + S R+ L+++SEA
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEAL 795
Query: 280 LDLERQLVKANGEIGHWRSKFXXXXXXXXX----------XXXXXXXKYSXXXXXXXXXX 329
++++L K E + F K
Sbjct: 796 ESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTEL 855
Query: 330 XTLIAKINNVEKQKSRLQSEVE-------VLIIDLEKA-NGTARELQKRTEQLERVNIEI 381
T+ K++ V +SE E I+DLEK +LQ + E + E+
Sbjct: 856 STVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKEL 915
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
K LE+ + Q + +L + Q +L + + L + +++ L
Sbjct: 916 KKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQL 957
Score = 49.2 bits (112), Expect = 3e-05
Identities = 78/420 (18%), Positives = 180/420 (42%), Gaps = 27/420 (6%)
Query: 19 TTDVNIEYSADL--SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE 76
T + NI+ DL ++L +I I+ + ER LR+ E++ L+ ++ + + ++
Sbjct: 149 TENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQ 208
Query: 77 EAEGGAESQ--FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
+ + + E EL++++ L++++ LE E + LK ++++ + Q +
Sbjct: 209 DLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKF--ESQYASSE 266
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
T ++ R+E K + VY V+ + K K ++++ ++ + T++E +K E+ + T
Sbjct: 267 ATISQLRSELSKGPQEVRVY-----VQELQKLKSSVNELTQKNQ-TLTENLLKKEQ-DYT 319
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
++ +++ +S++NI+ +DL + + + S +
Sbjct: 320 KLEEKHNEESVSKKNIQATLHQKDL--DCQQLQSRLSASETSLHRIHVELSEKGEATQKL 377
Query: 255 XASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX 314
L +VE + ++ + ++ + R + E+ ++ EI SK
Sbjct: 378 KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437
Query: 315 XXKY---SXXXXXXXXXXXTLIAKINNVEKQ-KSRLQSEVEVLIIDLEKANGTARELQKR 370
+ S L K++ +E+Q K ++ + E L L+K Q+
Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTE-LQHQLDKTK------QQH 490
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
EQ + + ++L E EQ R + K ++Q + L K++E L +E + +
Sbjct: 491 QEQ-QALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDL 549
Score = 47.6 bits (108), Expect = 1e-04
Identities = 88/433 (20%), Positives = 171/433 (39%), Gaps = 33/433 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE---GGAESQFEIN 89
LS +E K + ++ + + ++ R+ E+ L ++ QL +L E E G A + +
Sbjct: 381 LSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQ 440
Query: 90 RKRDTE-LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ +E L+ + + D+ L+ LK+K V + E QL KTK + +++++
Sbjct: 441 RQLSSEKLMDKEQQVADLQLKLSRLEEQLKEK----VTNSTELQHQLDKTKQQHQEQQAL 496
Query: 149 FQ---AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI------- 198
Q A++ E +E V ++ + + LE + + I L + D+
Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAG 556
Query: 199 ---TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
T+ +L ++N L EV L N++N Q
Sbjct: 557 EGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRV 616
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
SL E + + QL E E L+ Q +KA E+
Sbjct: 617 LSL---ETSVNELNSQLNESKEKVSQLDIQ-IKAKTELLLSAEAAKTAQRADLQNHLDTA 672
Query: 316 XKYSXXXXXXXXXXXTLI----AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
T + AK+ + ++ S+L+S ++ EL+ +
Sbjct: 673 QNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI 732
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ--RVSHELDKTREQKDALARENKK 429
++LE ++E+K+ E+ +Q +Q QR L N EL+ +S +L+ +E + + +K
Sbjct: 733 KKLEADSLEVKASKEQALQDLQQ-QRQL-NTDLELRATELSKQLEMEKEIVSSTRLDLQK 790
Query: 430 MGDDLHDARANIT 442
+ L + +T
Sbjct: 791 KSEALESIKQKLT 803
Score = 44.8 bits (101), Expect = 7e-04
Identities = 72/402 (17%), Positives = 154/402 (38%), Gaps = 17/402 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L+ ++K+ + ++++ EL E K + Q L L+ A+ + + +
Sbjct: 628 SQLNESKEKVSQLDIQIKAKTELLLSAEAAK---TAQRADLQNHLDTAQNALQDKHQELN 684
Query: 91 KRDTELLKLRKLLEDVHLE-SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K T+L ++ L+D S+ +HL K+ +E + +++ ++L E + K
Sbjct: 685 KITTQLDQVTAKLQDKQEHCSQLESHL--KEYKEKYLSLEQKTEEL-------EGQIKKL 735
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+A+ E+ A E ++ + LE+ +EL ++E + + IV T + E
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLE-MEKEIVSSTRLDLQKKSEA 794
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+E +K Q L E LK + L +V+++ E++
Sbjct: 795 LESIK--QKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALM 852
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+L + + L + E K +
Sbjct: 853 TELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQ 912
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETV 389
L + ++ +L+ E+ + L +A T ++ +K +QL+ E+K E+
Sbjct: 913 KELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKK 972
Query: 390 QLYEQTQRDLRNKQTELQRVSHELDKTREQ-KDALARENKKM 430
+ E Q +L+ + + ++L + Q LA E +K+
Sbjct: 973 KQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Score = 44.0 bits (99), Expect = 0.001
Identities = 69/400 (17%), Positives = 158/400 (39%), Gaps = 27/400 (6%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEINRKRDTELLKLRKL 102
Q L SE+ + + E++ ADL +++ +L E+L+E E Q ++++ +
Sbjct: 440 QRQLSSEKLMDK--EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ------ 491
Query: 103 LEDVHLESEETAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEKEK---SKFQAEVYELL 157
E L+ TA L + +N ++++ E+ ++ +A +K K S + E +L
Sbjct: 492 -EQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLY 550
Query: 158 AQVENVTKEKITISKTCER---LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
A+++ E +++ E+ L+ +++L ++ + + + QE ++
Sbjct: 551 AKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLR 610
Query: 215 EVQDLKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
QD +++E V L SQ+ ++ ++ L+
Sbjct: 611 AAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLD 670
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
A D ++L K ++ +K +Y L
Sbjct: 671 TAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLK-EYKEKYLSLEQKTEELE 729
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+I +E +++ E + DL++ +L+ R +L + +LE ++
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSK-------QLEMEKEIVS 782
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
T+ DL+ K L+ + +L K E+K L ++ + + +
Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQE 822
Score = 44.0 bits (99), Expect = 0.001
Identities = 49/195 (25%), Positives = 91/195 (46%), Gaps = 10/195 (5%)
Query: 30 LSALSRLED-KIRLIQDDLESERE---LRQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
+ ++ L+D K LIQ LE + + L+ +E+EK + + Q+ + EE + +
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELK---KEF 1211
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
E K +E+ K +++ H E+E + E + +++ + + EK+
Sbjct: 1212 IEKEAKLHSEI-KEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQ 1270
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
+ E+ L A V+N E+ + + C + E I +L K+ EL R + D T+ Q L
Sbjct: 1271 TDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKL-DNTTAVQEL 1329
Query: 206 SQENIEL-VKEVQDL 219
+EN L +K Q L
Sbjct: 1330 GRENQSLQIKHTQAL 1344
Score = 42.3 bits (95), Expect = 0.004
Identities = 74/390 (18%), Positives = 153/390 (39%), Gaps = 22/390 (5%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
++L+ E E Q +++++A V S L+ E Q E + + + +++ L E
Sbjct: 107 EELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLE----QQLEEAQTENFNIKQMKDLFE 162
Query: 105 DVHLE-SEETAHLLKKKNQEIVIDFQEQIDQ-LTKTKARAEKEKSKFQAEVYELLAQ--V 160
+ + E A + K ++E + +E +Q +T+ KE + Q ELL + +
Sbjct: 163 QKAAQLATEIADIKSKYDEERSL--REAAEQKVTRLTEELNKEATVIQDLKTELLQRPGI 220
Query: 161 ENVT---KEKITISKTCERLEITISELHIKIEELNRTIVD-ITSHKQRLSQENIELVKEV 216
E+V KE + + + + + K+++ ++ S + +SQ EL K
Sbjct: 221 EDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKKFESQYASSEATISQLRSELSKGP 280
Query: 217 QDLKVNIENVVYLKSQI--ASQXXXXXXXXXXXXXXXXXXXASLHQVE-IDLESVRVQLE 273
Q+++V ++ + LKS + +Q H E + ++++ L
Sbjct: 281 QEVRVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLH 340
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
++ L+ +L + + H + L
Sbjct: 341 QKDLDCQQLQSRLSASETSL-HRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQ 399
Query: 334 AKINNVEKQKSRLQSEVEVL---IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
+ E+ +LQSE+ L +++ E+ G A K QL + K + +Q
Sbjct: 400 QQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQ 459
Query: 391 L-YEQTQRDLRNKQTELQRVSHELDKTREQ 419
L + + L+ K T + H+LDKT++Q
Sbjct: 460 LKLSRLEEQLKEKVTNSTELQHQLDKTKQQ 489
Score = 39.9 bits (89), Expect = 0.021
Identities = 46/196 (23%), Positives = 86/196 (43%), Gaps = 12/196 (6%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK 98
K L QD + E++L++R + + + ++ E + E AE + EI +++ E+ K
Sbjct: 1084 KATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIE-EIKCRQEKEITK 1142
Query: 99 LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA 158
L + L+ LES + LK Q ++ E + KA E+EK Q ++
Sbjct: 1143 LNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKK 1202
Query: 159 QVENVTKEKI----TISKTCERLEITI-------SELHIKIEELNRTIVDITSHKQRLSQ 207
+ E + KE I + + E+ + ++L ++I LN + + Q +
Sbjct: 1203 EEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR 1262
Query: 208 ENIELVKEVQDLKVNI 223
EL K+ DL+ I
Sbjct: 1263 RVSELEKQTDDLRGEI 1278
Score = 36.3 bits (80), Expect = 0.26
Identities = 43/213 (20%), Positives = 90/213 (42%), Gaps = 11/213 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESER-------ELRQRIEREKADLSVQVIQLSERLEE 77
E A L +E+K+ L Q+DL S R +L Q ++ KA L + ++L+E
Sbjct: 1041 ELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQE 1100
Query: 78 AEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ + ++ EL+ + L ++ + K N+E+ E I ++T
Sbjct: 1101 RCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITN 1160
Query: 138 TKARAE---KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNR 193
K + ++K + Q + L A VE + + + ++ E + + I+ E +L+
Sbjct: 1161 LKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHS 1220
Query: 194 TIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
I + ++ + +L ++ L N+ V
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITALNENLGTV 1253
>AK001254-1|BAA91584.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ10392 fis, clone NT2RM4000169, weakly similar to
INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO1. ).
Length = 636
Score = 52.4 bits (120), Expect = 4e-06
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 9/212 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S + ED ++ + D L + E + + +A +I L+ A E +
Sbjct: 20 SVIKERED-LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 78
Query: 91 KRDTELLKLRKLLEDVH--LESEETAHLLKKKNQEIVIDFQEQI----DQLTKTKARAEK 144
R +LLK + LED+ L+ E+ LL+ KN E V +++ D+L T ++ K
Sbjct: 79 DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 138
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E Q + L + + N E+ + +L+ +L I +LN ++ K
Sbjct: 139 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 198
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQ 236
L +EN L+ ++Q L ++N L+ + S+
Sbjct: 199 LEEENRHLLDQIQTLM--LQNRTLLEQNMESK 228
Score = 31.9 bits (69), Expect = 5.5
Identities = 24/104 (23%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L+ + +E + L+ E E ++++ + A E +K + +R+N L+ET L
Sbjct: 84 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVL 143
Query: 392 ---YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
++ + L N + E R+ E K +EQ L + K+ +
Sbjct: 144 QTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNN 187
>AB033038-1|BAA86526.2| 802|Homo sapiens KIAA1212 protein protein.
Length = 802
Score = 52.4 bits (120), Expect = 4e-06
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 9/212 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S + ED ++ + D L + E + + +A +I L+ A E +
Sbjct: 100 SVIKERED-LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 158
Query: 91 KRDTELLKLRKLLEDVH--LESEETAHLLKKKNQEIVIDFQEQI----DQLTKTKARAEK 144
R +LLK + LED+ L+ E+ LL+ KN E V +++ D+L T ++ K
Sbjct: 159 DRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 218
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E Q + L + + N E+ + +L+ +L I +LN ++ K
Sbjct: 219 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 278
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQ 236
L +EN L+ ++Q L ++N L+ + S+
Sbjct: 279 LEEENRHLLDQIQTLM--LQNRTLLEQNMESK 308
Score = 40.3 bits (90), Expect = 0.016
Identities = 63/318 (19%), Positives = 131/318 (41%), Gaps = 16/318 (5%)
Query: 134 QLTKTKARA-EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN 192
Q KT+ + E + + QA++ L Q ++ ++ T+ +L++ S L+ + L
Sbjct: 22 QALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLM 81
Query: 193 RTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV--YLKSQIASQXXXXXXXXXXXXXX 250
+ + L EN ++KE +DLK ++++ + K ++ +
Sbjct: 82 NQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHG 141
Query: 251 XXXXXASLHQVE-IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
+VE DLE QL ++ DLE+ L K E +K
Sbjct: 142 TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKML-KVEQEKMLLENKNHETVAAEYK 200
Query: 310 XXXXXXXK----YS---XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG 362
+ YS L + +NN + +++RL++E L ++ +
Sbjct: 201 KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDI 260
Query: 363 TARELQKRTEQLERV--NIEIKSR-LEETVQLYEQTQRDLRNKQTELQRVSH-ELDKTRE 418
T+ +L + E L ++ N+E ++R L + +Q R L + E + + H E + +
Sbjct: 261 TSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYID 320
Query: 419 QKDALARENKKMGDDLHD 436
+ + L R+ +K+ + + D
Sbjct: 321 KLNELRRQKEKLEEKIMD 338
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 52.0 bits (119), Expect = 5e-06
Identities = 82/434 (18%), Positives = 176/434 (40%), Gaps = 35/434 (8%)
Query: 24 IEYSADLSALSRLEDKIR---LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+E L+ L E K++ ++Q + ++ + +++ L + +
Sbjct: 726 VEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSE 785
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQLTKT 138
G ++ ++ + +++ L + + ES + + + ++ + +E+ + + QE + ++++
Sbjct: 786 GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQV 845
Query: 139 KARAEKE----KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
K EKE K KF AE E V+ +E T++K ++ E + L +E+L
Sbjct: 846 KETLEKELQILKEKF-AEASEEAVSVQRSMQE--TVNKLHQKEE-QFNMLSSDLEKLREN 901
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX----- 249
+ D+ + + + +L+K + L+ +I ++ + SQ
Sbjct: 902 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEEL 961
Query: 250 ----XXXXXXASLHQVEIDLESVRVQLEEES------EARLDLERQLVKANGEIGHWRSK 299
AS Q I+ +V+ + ++ E + +LER+L ++ ++
Sbjct: 962 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1021
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K+ K+ ++ S L E+E L EK
Sbjct: 1022 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 1081
Query: 360 ANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQTELQRVSHELDKT 416
A TA + + EQ+ + E + LE+T Q + Q +L K+ L+ V EL+K+
Sbjct: 1082 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV-EELNKS 1140
Query: 417 REQKDALARENKKM 430
K+ L EN+KM
Sbjct: 1141 ---KELLTVENQKM 1151
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/395 (18%), Positives = 153/395 (38%), Gaps = 19/395 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 942 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 1000
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 1001 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1060
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 1061 AREENSGLLQELEELRKQ-AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 1115
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 1116 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1175
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 1176 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1231
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 1232 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 1287
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ ++ +R L + + E ++ +E +
Sbjct: 1288 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ 1322
Score = 44.8 bits (101), Expect = 7e-04
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 17/255 (6%)
Query: 33 LSRLEDKIRLIQD---DLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L++LE++ R ++D +E E + +E +K+ +S +LE A Q +
Sbjct: 428 LNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISEDPENTQTKLEHARIKELEQSLLF 486
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K T+ KL++ LED + + K + E+ D ++ ++ + + R E K
Sbjct: 487 EK--TKADKLQRELEDTRVATVSE----KSRIMELEKDLALRVQEVAELRRRLESNKPAG 540
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQRLSQ 207
++ L Q + +EK+ +++T + EIT + H + E + I + + ++LS+
Sbjct: 541 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 600
Query: 208 ENIELVKEVQDL-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
EN L +++ K N + + KS+ IAS A +++
Sbjct: 601 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 660
Query: 263 IDLESVRVQLEEESE 277
+E +R+ + E E
Sbjct: 661 TQIEKMRLDYQHEIE 675
Score = 36.7 bits (81), Expect = 0.19
Identities = 48/202 (23%), Positives = 93/202 (46%), Gaps = 18/202 (8%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
TT +++ S S+LS + + S R R + E + + I + L+EA
Sbjct: 302 TTSASLKRSPSASSLSSMSSVASSV-----SSRPSRTGLLTETSSRYARKISGTTALQEA 356
Query: 79 EGGAESQFE-INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E + +RD E ++ K V E E+ L + + + V++ + ++DQL
Sbjct: 357 LKEKQQHIEQLLAERDLERAEVAKATSHVG-EIEQELALARDGHDQHVLELEAKMDQLRT 415
Query: 138 TKARAEKEKSKFQAEVYELLAQVEN----VTKEKIT------ISKTCERLEITISEL-HI 186
A++EK + ++ E +VE+ V +E IT S+ E E T ++L H
Sbjct: 416 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHA 475
Query: 187 KIEELNRTIVDITSHKQRLSQE 208
+I+EL ++++ + +L +E
Sbjct: 476 RIKELEQSLLFEKTKADKLQRE 497
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/434 (18%), Positives = 177/434 (40%), Gaps = 35/434 (8%)
Query: 24 IEYSADLSALSRLEDKIR---LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+E L+ L E K++ ++Q + ++ + +++ L + +
Sbjct: 680 VEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKLLDLDALRKASSE 739
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQLTKT 138
G ++ ++ + +++ L + + ES + + + ++ + +E+ + + QE + ++++
Sbjct: 740 GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQV 799
Query: 139 KARAEKE----KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
K EKE K KF AE E V+ +E T++K ++ E + L +E+L
Sbjct: 800 KETLEKELQILKEKF-AEASEEAVSVQRSMQE--TVNKLHQKEE-QFNMLSSDLEKLREN 855
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX----- 249
+ D+ + + + +L+K + L+ +I ++ + +SQ
Sbjct: 856 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 915
Query: 250 ----XXXXXXASLHQVEIDLESVRVQLEEES------EARLDLERQLVKANGEIGHWRSK 299
AS Q I+ +V+ + ++ E + +LER+L ++ ++
Sbjct: 916 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 975
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K+ K+ ++ S L E+E L +K
Sbjct: 976 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADK 1035
Query: 360 ANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQTELQRVSHELDKT 416
A TA + + EQ+ + E + LE+T Q + Q +L K+ L+ V EL+K+
Sbjct: 1036 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV-EELNKS 1094
Query: 417 REQKDALARENKKM 430
K+ L EN+KM
Sbjct: 1095 ---KELLTVENQKM 1105
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/395 (18%), Positives = 153/395 (38%), Gaps = 19/395 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 896 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 954
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 955 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1014
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 1015 AREENSGLLQELEELRKQ-ADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 1069
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 1070 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1129
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 1130 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 1186 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 1241
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ ++ +R L + + E ++ +E +
Sbjct: 1242 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ 1276
Score = 41.9 bits (94), Expect = 0.005
Identities = 53/244 (21%), Positives = 104/244 (42%), Gaps = 13/244 (5%)
Query: 46 DLESEREL-RQRIEREKADLSVQVIQLSERLEEAEGGAE---SQFEINRKRDTELLKLRK 101
++E E L R ++ +L ++ QL +E A+ +Q E KR E L+ R
Sbjct: 387 EIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLE-EEKRKVEDLQFRV 445
Query: 102 LLEDVHLESEETAHLLKKKN-QEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
E + E A + +K E+ D ++ ++ + + R E K ++ L Q
Sbjct: 446 EEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE 505
Query: 161 ENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ +EK+ +++T + EIT + H + E + I + + ++LS+EN L +++
Sbjct: 506 ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEH 565
Query: 219 L-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
K N + + KS+ IAS A +++ +E +R+ +
Sbjct: 566 ANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQ 625
Query: 274 EESE 277
E E
Sbjct: 626 HEIE 629
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 51.6 bits (118), Expect = 6e-06
Identities = 81/434 (18%), Positives = 177/434 (40%), Gaps = 35/434 (8%)
Query: 24 IEYSADLSALSRLEDKIR---LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+E L+ L E K++ ++Q + ++ + +++ L + +
Sbjct: 715 VEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSE 774
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQLTKT 138
G ++ ++ + +++ L + + ES + + + ++ + +E+ + + QE + ++++
Sbjct: 775 GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQV 834
Query: 139 KARAEKE----KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
K EKE K KF AE E V+ +E T++K ++ E + L +E+L
Sbjct: 835 KETLEKELQILKEKF-AEASEEAVSVQRSMQE--TVNKLHQKEE-QFNMLSSDLEKLREN 890
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX----- 249
+ D+ + + + +L+K + L+ +I ++ + +SQ
Sbjct: 891 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 950
Query: 250 ----XXXXXXASLHQVEIDLESVRVQLEEES------EARLDLERQLVKANGEIGHWRSK 299
AS Q I+ +V+ + ++ E + +LER+L ++ ++
Sbjct: 951 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1010
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K+ K+ ++ S L E+E L +K
Sbjct: 1011 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADK 1070
Query: 360 ANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQTELQRVSHELDKT 416
A TA + + EQ+ + E + LE+T Q + Q +L K+ L+ V EL+K+
Sbjct: 1071 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV-EELNKS 1129
Query: 417 REQKDALARENKKM 430
K+ L EN+KM
Sbjct: 1130 ---KELLTVENQKM 1140
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/395 (18%), Positives = 153/395 (38%), Gaps = 19/395 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 931 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 989
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 990 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1049
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 1050 AREENSGLLQELEELRKQ-ADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 1104
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 1105 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1164
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 1165 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 1221 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 1276
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ ++ +R L + + E ++ +E +
Sbjct: 1277 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ 1311
Score = 46.0 bits (104), Expect = 3e-04
Identities = 59/258 (22%), Positives = 112/258 (43%), Gaps = 22/258 (8%)
Query: 38 DKIRLIQDDLESER-ELRQRIEREKADLSVQVIQLSERLEE---AEGGAESQFEINRKRD 93
D++R + + + E+ EL ++E EK +V L R+EE +G E+Q ++ R
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEEKR----KVEDLQFRVEEESITKGDLETQTKLEHARI 466
Query: 94 TEL---LKLRKLLEDV---HLESEETAHLLKKKN-QEIVIDFQEQIDQLTKTKARAEKEK 146
EL L K D LE A + +K E+ D ++ ++ + + R E K
Sbjct: 467 KELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNK 526
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQR 204
++ L Q + +EK+ +++T + EIT + H + E + I + + ++
Sbjct: 527 PAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEK 586
Query: 205 LSQENIELVKEVQDL-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLH 259
LS+EN L +++ K N + + KS+ IAS A
Sbjct: 587 LSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFA 646
Query: 260 QVEIDLESVRVQLEEESE 277
+++ +E +R+ + E E
Sbjct: 647 ELKTQIEKMRLDYQHEIE 664
Score = 39.9 bits (89), Expect = 0.021
Identities = 43/191 (22%), Positives = 85/191 (44%), Gaps = 7/191 (3%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
TT +++ S S+LS + + S R R + E + + I + L+EA
Sbjct: 302 TTSASLKRSPSASSLSSMSSVASSV-----SSRPSRTGLLTETSSRYARKISGTTALQEA 356
Query: 79 EGGAESQFE-INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E + +RD E ++ K V E E+ L + + + V++ + ++DQL
Sbjct: 357 LKEKQQHIEQLLAERDLERAEVAKATSHVG-EIEQELALARDGHDQHVLELEAKMDQLRT 415
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
A++EK + ++ E +VE++ S T LE H +I+EL ++++
Sbjct: 416 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHARIKELEQSLLF 475
Query: 198 ITSHKQRLSQE 208
+ +L +E
Sbjct: 476 EKTKADKLQRE 486
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 51.6 bits (118), Expect = 6e-06
Identities = 50/212 (23%), Positives = 106/212 (50%), Gaps = 20/212 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RL K+ ++++++ E++ Q + DL + QL + +E +E Q +I + +
Sbjct: 427 RLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE 486
Query: 95 ELLK-LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT---KARAEKEKSKFQ 150
L + + L + + +E ++K+N+ + +E +L+K K + +KE ++
Sbjct: 487 HLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK 546
Query: 151 AE---VYELLAQVENVTKE------KITISK-TCERLEITI---SELHIKIEELNRTI-- 195
+ EL ++ ++ KE KIT K TCE++E SEL + +L +T+
Sbjct: 547 EKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS 606
Query: 196 -VDITSHKQRLSQENIELVKEVQDLKVNIENV 226
++T + L +EN +L +E +L+ N+E++
Sbjct: 607 FKNLTFQLESLEKENSQLDEENLELRRNVESL 638
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 282 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 332
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 333 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 392
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 393 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 452
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 453 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 510
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 511 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 566
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 567 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 626
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 627 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 679
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/206 (21%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 396 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 455
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 456 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 514
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 515 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 563
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQ 232
+EN L K++ +LK+ E + L+ +
Sbjct: 564 KENELLQKKITNLKITCEKIEALEQE 589
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 123 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 182
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 183 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 238
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 239 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 290
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 291 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 349
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 350 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 402
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 403 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 461
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 462 QLEKTIE 468
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 416 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 475
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 476 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 529
Score = 38.3 bits (85), Expect = 0.064
Identities = 48/189 (25%), Positives = 88/189 (46%), Gaps = 23/189 (12%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----------IEREKADLSVQVIQLSERLEEAEG 80
S LS++E + R I+ +LE +E +R +E+E L ++ L E+ E
Sbjct: 526 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 585
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQIDQLTKT 138
+ E+ R E KL+K L+ + + L K+ +Q E ++ + ++ L
Sbjct: 586 LEQENSELER----ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC- 640
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTK--EKITIS-KTCERLEITISELHIKIEELNRTI 195
A + ++ Q E EL ++ E + K E + S K ERLE++ L I+ + L +T+
Sbjct: 641 ---ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTL 697
Query: 196 VDITSHKQR 204
+ K+R
Sbjct: 698 ENSNKKKKR 706
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 407 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 466
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 467 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 525
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 526 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 585
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 586 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 641
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 642 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 698 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 757
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 758 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 790
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 448 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 507
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 508 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 567
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 568 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 620
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 621 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 668
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 669 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 725
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 726 GREQELEQAR 735
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 885 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 944
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 945 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1004
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 1005 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1063
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1064 KLRESQEGREVQRQ 1077
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 604 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 663
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 664 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 722
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 723 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 782
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 783 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 839
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 840 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 899
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 900 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 957
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 958 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 1017
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1018 RLQEQARDLGKQRDSCLREAEELRTQL 1044
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 438 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 496
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 497 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 555
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 556 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 615
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 616 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 675
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 676 LEQEVARQGLEGSLRVAEQAQEALEQQL 703
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 469 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 528
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 529 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 587
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 588 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 647
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 648 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 707
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 708 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 766
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 767 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 826
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 827 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 870
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 37 EDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+++ R + L SE R+LR + E A + +V +L E+ + +S + T+
Sbjct: 984 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQ 1043
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L + + E E L++ + + QE +L ++ KE+ + E
Sbjct: 1044 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA-GELRRSLGEGAKEREALRRSNEE 1102
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L + V+ E+I++ E E ++ L + + ++ + Q + + +E +E
Sbjct: 1103 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1162
Query: 216 VQDLK 220
+Q+L+
Sbjct: 1163 LQELR 1167
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/128 (19%), Positives = 62/128 (48%), Gaps = 3/128 (2%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-- 84
+ ++++L L+++ +L+Q +L +L + E+ +L+++ +SER E ES
Sbjct: 41 ATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERDTEHSQDLESAL 100
Query: 85 -QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+ E ++R L ++ +L + ++ L + +++ D+ +L +A
Sbjct: 101 IRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWR 160
Query: 144 KEKSKFQA 151
+E+ F A
Sbjct: 161 REEESFNA 168
Score = 35.5 bits (78), Expect = 0.45
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLES-ERELRQ------RIEREKADLSVQVIQLSERLEEAE 79
+A L+ + +L+D+ RL+Q+ L S +R L Q +ER L + L L++ E
Sbjct: 1708 AAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1767
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E + E +L + L LE E +++ ++V+ EQ + +
Sbjct: 1768 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV--LEQSHSPAQLE 1825
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
A++++ + Q EV E L + T+ + + R +
Sbjct: 1826 VDAQQQQLELQQEV-ERLRSAQAQTERTLEARERAHRQRV 1864
Score = 35.1 bits (77), Expect = 0.59
Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 3/286 (1%)
Query: 5 AKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADL 64
A T + T G V A + L + + L S R+ +++
Sbjct: 1581 AGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTAC 1640
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
L ERL+ A + + ++ LR + D+ L+ E L++ +E+
Sbjct: 1641 EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL-REV 1699
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ QE T + + E+ Q + L + + EK + ++ RLE L
Sbjct: 1700 LRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1759
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++++ R + RLS E L + + ++ + Q+ +Q
Sbjct: 1760 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSH 1819
Query: 245 XXXXXXXXXXXASLH-QVEID-LESVRVQLEEESEARLDLERQLVK 288
L Q E++ L S + Q E EAR RQ V+
Sbjct: 1820 SPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVR 1865
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 209 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 268
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 269 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 328
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 329 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 359
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 526 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 585
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 586 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 644
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 705 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 760
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 761 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 817 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 876
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 877 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 909
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 567 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 626
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 739
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 740 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 787
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 844
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 845 GREQELEQAR 854
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 1004 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1063
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 1064 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1123
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 1124 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1182
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1183 KLRESQEGREVQRQ 1196
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 723 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 782
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 783 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 842 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 901
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 902 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 958
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 959 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 1076
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 1136
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1137 RLQEQARDLGKQRDSCLREAEELRTQL 1163
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 557 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 615
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 616 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 674
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 675 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 734
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 735 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 795 LEQEVARQGLEGSLRVAEQAQEALEQQL 822
Score = 38.7 bits (86), Expect = 0.048
Identities = 71/401 (17%), Positives = 161/401 (40%), Gaps = 28/401 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
+ ++++L L+++ +L+Q +L +L + E+ +L+++ +SERLE+A +
Sbjct: 70 ATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGEL 129
Query: 87 EINRKRD--TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
E R + ++LR+ L+ E+ ++ ++K Q Q Q + + + + +
Sbjct: 130 ETQEPRGLVRQSVELRR-----QLQEEQASY--RRKLQAYQEGQQRQAQLVQRLQGKILQ 182
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + +LL + + ++++ ++ + LE + I++EE + +
Sbjct: 183 YKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESAL----IRLEEEQQRSASLAQVNAM 238
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L ++ + Q L +I V ++ + ++ H +
Sbjct: 239 LREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLL 298
Query: 265 LESVRVQLEE-ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
L V SE ++ ER L++ GE+ +
Sbjct: 299 LWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALE 358
Query: 324 XXXXXXXTLIAKI-NNVEKQKSRLQSEVEVLIIDLEKANGTAR---------ELQKRTEQ 373
L ++ + V ++K Q +++ DL+KA+ +AR L+K+ +
Sbjct: 359 KQALLQAQLEEQLRDKVLREKDLAQQQMQ---SDLDKADLSARVTELGLAVKRLEKQNLE 415
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTE-LQRVSHEL 413
++VN ++ +LE L Q Q L + E LQ+ +L
Sbjct: 416 KDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDL 456
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 588 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 647
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 648 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 706
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 707 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 767 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 826
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 827 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 885
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 886 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 945
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 946 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 989
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 37 EDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+++ R + L SE R+LR + E A + +V +L E+ + +S + T+
Sbjct: 1103 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQ 1162
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L + + E E L++ + + QE +L ++ KE+ + E
Sbjct: 1163 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA-GELRRSLGEGAKEREALRRSNEE 1221
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L + V+ E+I++ E E ++ L + + ++ + Q + + +E +E
Sbjct: 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Query: 216 VQDLK 220
+Q+L+
Sbjct: 1282 LQELR 1286
Score = 35.5 bits (78), Expect = 0.45
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLES-ERELRQ------RIEREKADLSVQVIQLSERLEEAE 79
+A L+ + +L+D+ RL+Q+ L S +R L Q +ER L + L L++ E
Sbjct: 1827 AAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E + E +L + L LE E +++ ++V+ EQ + +
Sbjct: 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV--LEQSHSPAQLE 1944
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
A++++ + Q EV E L + T+ + + R +
Sbjct: 1945 VDAQQQQLELQQEV-ERLRSAQAQTERTLEARERAHRQRV 1983
Score = 35.1 bits (77), Expect = 0.59
Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 3/286 (1%)
Query: 5 AKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADL 64
A T + T G V A + L + + L S R+ +++
Sbjct: 1700 AGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTAC 1759
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
L ERL+ A + + ++ LR + D+ L+ E L++ +E+
Sbjct: 1760 EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL-REV 1818
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ QE T + + E+ Q + L + + EK + ++ RLE L
Sbjct: 1819 LRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1878
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++++ R + RLS E L + + ++ + Q+ +Q
Sbjct: 1879 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSH 1938
Query: 245 XXXXXXXXXXXASLH-QVEID-LESVRVQLEEESEARLDLERQLVK 288
L Q E++ L S + Q E EAR RQ V+
Sbjct: 1939 SPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVR 1984
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 328 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 388 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 447
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 448 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 478
>BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 389 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 448
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 449 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 507
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 508 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 567
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 568 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 623
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 624 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 679
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 680 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 739
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 740 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 772
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 430 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 489
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 490 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 549
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 550 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 602
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 603 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 650
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 651 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 707
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 708 GREQELEQAR 717
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 867 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 926
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 927 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 986
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 987 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1045
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1046 KLRESQEGREVQRQ 1059
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 586 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 645
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 646 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 704
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 705 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 764
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 765 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 821
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 822 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 881
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 882 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 939
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 940 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 999
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1000 RLQEQARDLGKQRDSCLREAEELRTQL 1026
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 420 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 478
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 479 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 537
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 538 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 597
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 598 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 657
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 658 LEQEVARQGLEGSLRVAEQAQEALEQQL 685
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 451 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 510
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 511 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 569
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 570 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 629
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 630 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 689
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 690 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 748
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 749 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 808
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 809 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 852
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 191 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 250
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 251 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 310
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 311 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 341
>BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 389 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 448
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 449 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 507
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 508 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 567
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 568 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 623
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 624 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 679
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 680 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 739
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 740 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 772
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 430 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 489
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 490 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 549
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 550 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 602
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 603 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 650
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 651 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 707
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 708 GREQELEQAR 717
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 867 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 926
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 927 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 986
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 987 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1045
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1046 KLRESQEGREVQRQ 1059
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 586 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 645
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 646 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 704
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 705 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 764
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 765 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 821
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 822 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 881
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 882 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 939
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 940 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 999
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1000 RLQEQARDLGKQRDSCLREAEELRTQL 1026
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 420 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 478
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 479 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 537
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 538 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 597
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 598 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 657
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 658 LEQEVARQGLEGSLRVAEQAQEALEQQL 685
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 451 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 510
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 511 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 569
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 570 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 629
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 630 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 689
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 690 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 748
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 749 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 808
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 809 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 852
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 191 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 250
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 251 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 310
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 311 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 341
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 51.6 bits (118), Expect = 6e-06
Identities = 81/434 (18%), Positives = 177/434 (40%), Gaps = 35/434 (8%)
Query: 24 IEYSADLSALSRLEDKIR---LIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+E L+ L E K++ ++Q + ++ + +++ L + +
Sbjct: 726 VEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSE 785
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKK-KNQEIVI-DFQEQIDQLTKT 138
G ++ ++ + +++ L + + ES + + + ++ + +E+ + + QE + ++++
Sbjct: 786 GKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQV 845
Query: 139 KARAEKE----KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRT 194
K EKE K KF AE E V+ +E T++K ++ E + L +E+L
Sbjct: 846 KETLEKELQILKEKF-AEASEEAVSVQRSMQE--TVNKLHQKEE-QFNMLSSDLEKLREN 901
Query: 195 IVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX----- 249
+ D+ + + + +L+K + L+ +I ++ + +SQ
Sbjct: 902 LADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEEL 961
Query: 250 ----XXXXXXASLHQVEIDLESVRVQLEEES------EARLDLERQLVKANGEIGHWRSK 299
AS Q I+ +V+ + ++ E + +LER+L ++ ++
Sbjct: 962 QLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1021
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
K+ K+ ++ S L E+E L +K
Sbjct: 1022 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADK 1081
Query: 360 ANG--TARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN-KQTELQRVSHELDKT 416
A TA + + EQ+ + E + LE+T Q + Q +L K+ L+ V EL+K+
Sbjct: 1082 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNV-EELNKS 1140
Query: 417 REQKDALARENKKM 430
K+ L EN+KM
Sbjct: 1141 ---KELLTVENQKM 1151
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/395 (18%), Positives = 153/395 (38%), Gaps = 19/395 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKAD-LSVQVIQLSERLEEAEGGAESQFEIN 89
S L+++ D++RL + D+E E +L+ E A L + ++ + E+++ A + E
Sbjct: 942 SQLTKMNDELRLKERDVE-ELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 1000
Query: 90 RKR-DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+K + +L L K +E H + +E ++ E +E + L KT E +
Sbjct: 1001 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1060
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ E LL ++E + K+ +K + E + + +E T+ + K Q
Sbjct: 1061 AREENSGLLQELEELRKQ-ADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK----QT 1115
Query: 209 NIELVKEVQDLKV-NIENVVYL--KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDL 265
N +L E+ LK N++NV L ++ + A Q L
Sbjct: 1116 NAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSAL 1175
Query: 266 ESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXX 325
+ V+L EE L R V ++ ++ RS
Sbjct: 1176 QEENVKLAEE----LGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1231
Query: 326 XXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRL 385
A + + + +L++EV V L N +A+ L + LE ++++ ++
Sbjct: 1232 QKSISITSALLTEKDAELEKLRNEVTV----LRGENASAKSLHSVVQTLESDKVKLELKV 1287
Query: 386 EETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
+ ++ +R L + + E ++ +E +
Sbjct: 1288 KNLELQLKENKRQLSSSSGNTDTQADEDERAQESQ 1322
Score = 44.8 bits (101), Expect = 7e-04
Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 17/255 (6%)
Query: 33 LSRLEDKIRLIQD---DLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
L++LE++ R ++D +E E + +E +K+ +S +LE A Q +
Sbjct: 428 LNQLEEEKRKVEDLQFRVEEESITKGDLE-QKSQISEDPENTQTKLEHARIKELEQSLLF 486
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
K T+ KL++ LED + + K + E+ D ++ ++ + + R E K
Sbjct: 487 EK--TKADKLQRELEDTRVATVSE----KSRIMELEKDLALRVQEVAELRRRLESNKPAG 540
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHI--KIEELNRTIVDITSHKQRLSQ 207
++ L Q + +EK+ +++T + EIT + H + E + I + + ++LS+
Sbjct: 541 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 600
Query: 208 ENIELVKEVQDL-KVNIENVVYLKSQ----IASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
EN L +++ K N + + KS+ IAS A +++
Sbjct: 601 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELK 660
Query: 263 IDLESVRVQLEEESE 277
+E +R+ + E E
Sbjct: 661 TQIEKMRLDYQHEIE 675
Score = 36.7 bits (81), Expect = 0.19
Identities = 48/202 (23%), Positives = 93/202 (46%), Gaps = 18/202 (8%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
TT +++ S S+LS + + S R R + E + + I + L+EA
Sbjct: 302 TTSASLKRSPSASSLSSMSSVASSV-----SSRPSRTGLLTETSSRYARKISGTTALQEA 356
Query: 79 EGGAESQFE-INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ E + +RD E ++ K V E E+ L + + + V++ + ++DQL
Sbjct: 357 LKEKQQHIEQLLAERDLERAEVAKATSHVG-EIEQELALARDGHDQHVLELEAKMDQLRT 415
Query: 138 TKARAEKEKSKFQAEVYELLAQVEN----VTKEKIT------ISKTCERLEITISEL-HI 186
A++EK + ++ E +VE+ V +E IT S+ E E T ++L H
Sbjct: 416 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHA 475
Query: 187 KIEELNRTIVDITSHKQRLSQE 208
+I+EL ++++ + +L +E
Sbjct: 476 RIKELEQSLLFEKTKADKLQRE 497
>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 51.6 bits (118), Expect = 6e-06
Identities = 77/404 (19%), Positives = 170/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 1057 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 1112
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 1113 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 1171
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 1172 TQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1231
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 1232 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1291
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 1292 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 1340
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 1393
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 1394 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 1437
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLESER---ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+++ ++E++ + +++L L+E + + + + + +
Sbjct: 1162 KIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1221
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 1222 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 1334
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 1335 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 1378
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 1379 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 1434
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 1435 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 1491
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 1492 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 1525
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 1215 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1274
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 1275 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1334
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 1335 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 1391
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 1392 DQVLEAKLEEVERLATELEKWKEK 1415
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 1401 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1460
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 1461 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 1518
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 1519 REERDQLVAALEIQ-LKALISSNVQKDNEI 1547
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 1386 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 1444
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 1445 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 1504
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 1505 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 1564
Query: 217 QDLK 220
D+K
Sbjct: 1565 MDIK 1568
Score = 31.1 bits (67), Expect = 9.7
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 42 LIQDDLESERELRQRIEREKADLSV--QVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
LIQ+ S +++ + +R K +++ Q + + E+ F+ N K DT L +
Sbjct: 748 LIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLII 807
Query: 100 RKLL---EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK---ARAEKEKSKFQAEV 153
L E V + + + + ++ + + Q+ K + A E K EV
Sbjct: 808 NNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEV 867
Query: 154 YELLAQVENVTKEKITISKTCERLEITI-SELHIKIEE---LNRTIVDITSHKQRLSQEN 209
+A++E++ + ++ +TI +EL + EE LN+ IV ++N
Sbjct: 868 RPNIAEIEDIRVLQEN-NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKN 926
Query: 210 IELVKEVQDLKVNIE 224
+ L KEVQ ++ N +
Sbjct: 927 LTLSKEVQQIQSNYD 941
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 51.6 bits (118), Expect = 6e-06
Identities = 77/404 (19%), Positives = 170/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 1017 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 1072
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 1073 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 1131
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 1132 TQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1191
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1251
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 1252 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 1300
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 1353
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 1354 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 1397
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLESER---ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+++ ++E++ + +++L L+E + + + + + +
Sbjct: 1122 KIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1181
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 1182 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1241
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 1242 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 1294
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 1295 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 1338
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 1339 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 1394
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 1395 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 1451
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 1452 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 1485
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 1175 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1234
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 1235 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1294
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 1295 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 1351
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 1352 DQVLEAKLEEVERLATELEKWKEK 1375
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1360
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 1361 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1420
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 1421 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 1478
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 1479 REERDQLVAALEIQ-LKALISSNVQKDNEI 1507
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 1346 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 1404
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 1405 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 1464
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 1465 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 1524
Query: 217 QDLK 220
D+K
Sbjct: 1525 MDIK 1528
Score = 31.1 bits (67), Expect = 9.7
Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 6/144 (4%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEINRKRDTELLKLRKLLEDV 106
E +E Q + +AD ++Q E LEE AE ++ K DT + +
Sbjct: 604 EVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICA-T 662
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+E+EE L+ K +I + + +L KTK +E K + E L+ ++E K+
Sbjct: 663 KVETEEATACLELKFNQIKAELAKTKGELIKTK----EELKKRENESDSLIQELETSNKK 718
Query: 167 KITISKTCERLEITISELHIKIEE 190
IT ++ + L I + I E
Sbjct: 719 IITQNQRIKELINIIDQKEDTINE 742
Score = 31.1 bits (67), Expect = 9.7
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 42 LIQDDLESERELRQRIEREKADLSV--QVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
LIQ+ S +++ + +R K +++ Q + + E+ F+ N K DT L +
Sbjct: 708 LIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLII 767
Query: 100 RKLL---EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK---ARAEKEKSKFQAEV 153
L E V + + + + ++ + + Q+ K + A E K EV
Sbjct: 768 NNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEV 827
Query: 154 YELLAQVENVTKEKITISKTCERLEITI-SELHIKIEE---LNRTIVDITSHKQRLSQEN 209
+A++E++ + ++ +TI +EL + EE LN+ IV ++N
Sbjct: 828 RPNIAEIEDIRVLQEN-NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKN 886
Query: 210 IELVKEVQDLKVNIE 224
+ L KEVQ ++ N +
Sbjct: 887 LTLSKEVQQIQSNYD 901
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 51.6 bits (118), Expect = 6e-06
Identities = 77/404 (19%), Positives = 170/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 1017 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 1072
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 1073 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 1131
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 1132 TQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1191
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 1192 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1251
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 1252 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 1300
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 1353
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 1354 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 1397
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLESER---ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+++ ++E++ + +++L L+E + + + + + +
Sbjct: 1122 KIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1181
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 1182 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1241
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 1242 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 1294
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 1295 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 1338
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 1339 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 1394
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 1395 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 1451
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 1452 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 1485
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 1175 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1234
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 1235 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1294
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 1295 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 1351
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 1352 DQVLEAKLEEVERLATELEKWKEK 1375
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1360
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 1361 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1420
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 1421 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 1478
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 1479 REERDQLVAALEIQ-LKALISSNVQKDNEI 1507
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 1346 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 1404
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 1405 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 1464
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 1465 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 1524
Query: 217 QDLK 220
D+K
Sbjct: 1525 MDIK 1528
Score = 31.1 bits (67), Expect = 9.7
Identities = 37/144 (25%), Positives = 63/144 (43%), Gaps = 6/144 (4%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEINRKRDTELLKLRKLLEDV 106
E +E Q + +AD ++Q E LEE AE ++ K DT + +
Sbjct: 604 EVTQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICA-T 662
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+E+EE L+ K +I + + +L KTK +E K + E L+ ++E K+
Sbjct: 663 KVETEEATACLELKFNQIKAELAKTKGELIKTK----EELKKRENESDSLIQELETSNKK 718
Query: 167 KITISKTCERLEITISELHIKIEE 190
IT ++ + L I + I E
Sbjct: 719 IITQNQRIKELINIIDQKEDTINE 742
Score = 31.1 bits (67), Expect = 9.7
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 42 LIQDDLESERELRQRIEREKADLSV--QVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
LIQ+ S +++ + +R K +++ Q + + E+ F+ N K DT L +
Sbjct: 708 LIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLII 767
Query: 100 RKLL---EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK---ARAEKEKSKFQAEV 153
L E V + + + + ++ + + Q+ K + A E K EV
Sbjct: 768 NNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEV 827
Query: 154 YELLAQVENVTKEKITISKTCERLEITI-SELHIKIEE---LNRTIVDITSHKQRLSQEN 209
+A++E++ + ++ +TI +EL + EE LN+ IV ++N
Sbjct: 828 RPNIAEIEDIRVLQEN-NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKN 886
Query: 210 IELVKEVQDLKVNIE 224
+ L KEVQ ++ N +
Sbjct: 887 LTLSKEVQQIQSNYD 901
>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 51.6 bits (118), Expect = 6e-06
Identities = 77/404 (19%), Positives = 170/404 (42%), Gaps = 32/404 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLED 105
+E+ E + I + + S Q+ +L +++E+ + + + E NR ++ E K +D
Sbjct: 1057 IEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKE----HKNQDD 1112
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQVE 161
+ E E LK++ QE + QI + + K RA E ++ ++A++ EL +E
Sbjct: 1113 LLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETILE 1171
Query: 162 NVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
E +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 1172 TQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQ 1231
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
L N++++ +L + A ++ DL+ + E
Sbjct: 1232 LTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEK 1291
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
D ++Q+ + E+ R + K + L K
Sbjct: 1292 LTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQRT 1340
Query: 339 VEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q + +
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQDQ 1393
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 1394 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 1437
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLESER---ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+++ ++E++ + +++L L+E + + + + + +
Sbjct: 1162 KIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1221
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 1222 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 1334
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 1335 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 1378
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 1379 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 1434
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 1435 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 1491
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 1492 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 1525
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 1215 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 1274
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 1275 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 1334
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 1335 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 1391
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 1392 DQVLEAKLEEVERLATELEKWKEK 1415
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 1401 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 1460
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 1461 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 1518
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 1519 REERDQLVAALEIQ-LKALISSNVQKDNEI 1547
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 1386 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 1444
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 1445 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 1504
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 1505 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 1564
Query: 217 QDLK 220
D+K
Sbjct: 1565 MDIK 1568
Score = 31.1 bits (67), Expect = 9.7
Identities = 43/195 (22%), Positives = 85/195 (43%), Gaps = 13/195 (6%)
Query: 42 LIQDDLESERELRQRIEREKADLSV--QVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
LIQ+ S +++ + +R K +++ Q + + E+ F+ N K DT L +
Sbjct: 748 LIQELETSNKKIITQNQRIKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSSLII 807
Query: 100 RKLL---EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK---ARAEKEKSKFQAEV 153
L E V + + + + ++ + + Q+ K + A E K EV
Sbjct: 808 NNKLICNETVEVPKDSKSKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEV 867
Query: 154 YELLAQVENVTKEKITISKTCERLEITI-SELHIKIEE---LNRTIVDITSHKQRLSQEN 209
+A++E++ + ++ +TI +EL + EE LN+ IV ++N
Sbjct: 868 RPNIAEIEDIRVLQEN-NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKN 926
Query: 210 IELVKEVQDLKVNIE 224
+ L KEVQ ++ N +
Sbjct: 927 LTLSKEVQQIQSNYD 941
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 407 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 466
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 467 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 525
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 526 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 585
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 586 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 641
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 642 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 697
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 698 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 757
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 758 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 790
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 448 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 507
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 508 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 567
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 568 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 620
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 621 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 668
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 669 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 725
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 726 GREQELEQAR 735
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 885 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 944
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 945 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1004
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 1005 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1063
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1064 KLRESQEGREVQRQ 1077
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 604 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 663
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 664 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 722
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 723 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 782
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 783 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 839
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 840 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 899
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 900 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 957
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 958 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 1017
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1018 RLQEQARDLGKQRDSCLREAEELRTQL 1044
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 438 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 496
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 497 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 555
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 556 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 615
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 616 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 675
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 676 LEQEVARQGLEGSLRVAEQAQEALEQQL 703
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 469 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 528
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 529 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 587
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 588 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 647
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 648 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 707
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 708 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 766
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 767 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 826
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 827 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 870
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 37 EDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+++ R + L SE R+LR + E A + +V +L E+ + +S + T+
Sbjct: 984 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQ 1043
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L + + E E L++ + + QE +L ++ KE+ + E
Sbjct: 1044 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA-GELRRSLGEGAKEREALRRSNEE 1102
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L + V+ E+I++ E E ++ L + + ++ + Q + + +E +E
Sbjct: 1103 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1162
Query: 216 VQDLK 220
+Q+L+
Sbjct: 1163 LQELR 1167
Score = 35.9 bits (79), Expect = 0.34
Identities = 25/128 (19%), Positives = 62/128 (48%), Gaps = 3/128 (2%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES-- 84
+ ++++L L+++ +L+Q +L +L + E+ +L+++ +SER E ES
Sbjct: 41 ATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERDTEHSQDLESAL 100
Query: 85 -QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+ E ++R L ++ +L + ++ L + +++ D+ +L +A
Sbjct: 101 IRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWR 160
Query: 144 KEKSKFQA 151
+E+ F A
Sbjct: 161 REEESFNA 168
Score = 35.5 bits (78), Expect = 0.45
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLES-ERELRQ------RIEREKADLSVQVIQLSERLEEAE 79
+A L+ + +L+D+ RL+Q+ L S +R L Q +ER L + L L++ E
Sbjct: 1708 AAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1767
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E + E +L + L LE E +++ ++V+ EQ + +
Sbjct: 1768 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV--LEQSHSPAQLE 1825
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
A++++ + Q EV E L + T+ + + R +
Sbjct: 1826 VDAQQQQLELQQEV-ERLRSAQAQTERTLEARERAHRQRV 1864
Score = 35.1 bits (77), Expect = 0.59
Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 3/286 (1%)
Query: 5 AKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADL 64
A T + T G V A + L + + L S R+ +++
Sbjct: 1581 AGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTAC 1640
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
L ERL+ A + + ++ LR + D+ L+ E L++ +E+
Sbjct: 1641 EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL-REV 1699
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ QE T + + E+ Q + L + + EK + ++ RLE L
Sbjct: 1700 LRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1759
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++++ R + RLS E L + + ++ + Q+ +Q
Sbjct: 1760 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSH 1819
Query: 245 XXXXXXXXXXXASLH-QVEID-LESVRVQLEEESEARLDLERQLVK 288
L Q E++ L S + Q E EAR RQ V+
Sbjct: 1820 SPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVR 1865
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 209 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 268
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 269 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 328
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 329 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 359
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 526 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 585
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 586 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 644
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 705 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 760
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 761 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 816
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 817 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 876
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 877 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 909
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 567 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 626
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 627 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 686
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 687 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 739
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 740 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 787
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 844
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 845 GREQELEQAR 854
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 1004 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1063
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 1064 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1123
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 1124 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1182
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1183 KLRESQEGREVQRQ 1196
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 723 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 782
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 783 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 842 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 901
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 902 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 958
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 959 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 1018
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 1019 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 1076
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 1077 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 1136
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1137 RLQEQARDLGKQRDSCLREAEELRTQL 1163
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 557 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 615
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 616 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 674
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 675 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 734
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 735 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 794
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 795 LEQEVARQGLEGSLRVAEQAQEALEQQL 822
Score = 38.7 bits (86), Expect = 0.048
Identities = 71/401 (17%), Positives = 161/401 (40%), Gaps = 28/401 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
+ ++++L L+++ +L+Q +L +L + E+ +L+++ +SERLE+A +
Sbjct: 70 ATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGEL 129
Query: 87 EINRKRD--TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
E R + ++LR+ L+ E+ ++ ++K Q Q Q + + + + +
Sbjct: 130 ETQEPRGLVRQSVELRR-----QLQEEQASY--RRKLQAYQEGQQRQAQLVQRLQGKILQ 182
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + +LL + + ++++ ++ + LE + I++EE + +
Sbjct: 183 YKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESAL----IRLEEEQQRSASLAQVNAM 238
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L ++ + Q L +I V ++ + ++ H +
Sbjct: 239 LREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLL 298
Query: 265 LESVRVQLEE-ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
L V SE ++ ER L++ GE+ +
Sbjct: 299 LWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALE 358
Query: 324 XXXXXXXTLIAKI-NNVEKQKSRLQSEVEVLIIDLEKANGTAR---------ELQKRTEQ 373
L ++ + V ++K Q +++ DL+KA+ +AR L+K+ +
Sbjct: 359 KQALLQAQLEEQLRDKVLREKDLAQQQMQ---SDLDKADLSARVTELGLAVKRLEKQNLE 415
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTE-LQRVSHEL 413
++VN ++ +LE L Q Q L + E LQ+ +L
Sbjct: 416 KDQVNKDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDL 456
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 588 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 647
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 648 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 706
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 707 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 766
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 767 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 826
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 827 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 885
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 886 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 945
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 946 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 989
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 37 EDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+++ R + L SE R+LR + E A + +V +L E+ + +S + T+
Sbjct: 1103 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQ 1162
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L + + E E L++ + + QE +L ++ KE+ + E
Sbjct: 1163 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA-GELRRSLGEGAKEREALRRSNEE 1221
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L + V+ E+I++ E E ++ L + + ++ + Q + + +E +E
Sbjct: 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Query: 216 VQDLK 220
+Q+L+
Sbjct: 1282 LQELR 1286
Score = 35.5 bits (78), Expect = 0.45
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLES-ERELRQ------RIEREKADLSVQVIQLSERLEEAE 79
+A L+ + +L+D+ RL+Q+ L S +R L Q +ER L + L L++ E
Sbjct: 1827 AAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1886
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E + E +L + L LE E +++ ++V+ EQ + +
Sbjct: 1887 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV--LEQSHSPAQLE 1944
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
A++++ + Q EV E L + T+ + + R +
Sbjct: 1945 VDAQQQQLELQQEV-ERLRSAQAQTERTLEARERAHRQRV 1983
Score = 35.1 bits (77), Expect = 0.59
Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 3/286 (1%)
Query: 5 AKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADL 64
A T + T G V A + L + + L S R+ +++
Sbjct: 1700 AGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTAC 1759
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
L ERL+ A + + ++ LR + D+ L+ E L++ +E+
Sbjct: 1760 EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL-REV 1818
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ QE T + + E+ Q + L + + EK + ++ RLE L
Sbjct: 1819 LRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1878
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++++ R + RLS E L + + ++ + Q+ +Q
Sbjct: 1879 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSH 1938
Query: 245 XXXXXXXXXXXASLH-QVEID-LESVRVQLEEESEARLDLERQLVK 288
L Q E++ L S + Q E EAR RQ V+
Sbjct: 1939 SPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVR 1984
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 328 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 387
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 388 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 447
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 448 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 478
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 51.6 bits (118), Expect = 6e-06
Identities = 66/408 (16%), Positives = 154/408 (37%), Gaps = 13/408 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D++ + D+L+S + +REK L +++Q + L++ E + ++ RKR+ E
Sbjct: 13 LQDQLSEMHDELDSAKRSE---DREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERE 69
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L+ L++ ++ LK++ + +E +++ TK + + +
Sbjct: 70 LTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAG 129
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
+V+ + +E + E LE +++L +IE+L ++ E +L +
Sbjct: 130 TEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEA 189
Query: 216 VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE 275
+ ++ + V + + ++ L + E +R E
Sbjct: 190 LVHVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEM 249
Query: 276 SEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
R L + + K E+ + +Y + K
Sbjct: 250 ENERWHLGKTIEKLQKEM----ADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQL-K 304
Query: 336 INNVEKQKSRL-----QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ 390
+E +KSRL Q + ++ +L E + + LE+ +++ LE
Sbjct: 305 EKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSH 364
Query: 391 LYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDAR 438
L + R ++ + ++ ++ EL++ R D L + + + R
Sbjct: 365 LKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLR 412
Score = 45.6 bits (103), Expect = 4e-04
Identities = 38/179 (21%), Positives = 92/179 (51%), Gaps = 9/179 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQL-SERLEEAEGGAESQFE-INR 90
+ ++EDK+ ++ +LE ER + + Q+ QL +E L+E + + + I+
Sbjct: 373 VKQMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLRNELLQERAARQDLECDKISL 432
Query: 91 KRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+R + LK R + LE + S+E L + + + + +++++ + +A + +
Sbjct: 433 ERQNKDLKSRIIHLEGSYRSSKEG---LVVQMEARIAELEDRLESEERDRANLQLSNRRL 489
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ +V EL+ QV++ E ++++ ++L + + + ++EE I + S K++L +E
Sbjct: 490 ERKVKELVMQVDD---EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRE 545
Score = 44.8 bits (101), Expect = 7e-04
Identities = 69/394 (17%), Positives = 156/394 (39%), Gaps = 27/394 (6%)
Query: 44 QDDLESERELRQRIEREKADLSV---QVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
++ + + R L +E + +LS + QLSE+L+E E + + + E L
Sbjct: 198 KEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLG 257
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQV 160
K +E + E + + + ++ ++ Q Q+D+ K + +E ++ Q ++ E +
Sbjct: 258 KTIEKLQKEMAD----IVEASRTSTLELQNQLDEY---KEKNRRELAEMQRQLKEKTLEA 310
Query: 161 ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK 220
E K ++T K + + + EL + R + + +Q L Q +L E++
Sbjct: 311 E---KSRLTAMKMQDGMRLMEEEL----RDYQRAQDEALTKRQLLEQTLKDLEYELEAKS 363
Query: 221 VNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARL 280
++ L Q+ + + + +E +R +L +E AR
Sbjct: 364 HLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERISRSREQMEQLRNELLQERAARQ 423
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
DLE + + +S+ + + N++
Sbjct: 424 DLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQ 483
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
RL+ +V+ L++ ++ E T+Q +++++ +K+ + + E+ R L
Sbjct: 484 LSNRRLERKVKELVMQVDD------EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDR-LE 536
Query: 401 NKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + +LQR EL++ + + L + M DL
Sbjct: 537 SSKKKLQR---ELEEQMDMNEHLQGQLNSMKKDL 567
Score = 41.9 bits (94), Expect = 0.005
Identities = 47/207 (22%), Positives = 105/207 (50%), Gaps = 21/207 (10%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-INRKRD- 93
LE ++ ++ +LE++ L+ R + +V QL LEE ++ E I+R R+
Sbjct: 348 LEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLTERISRSREQ 407
Query: 94 -----TELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE--K 146
ELL+ R +D LE ++ + L+++N+ D + +I L + R+ KE
Sbjct: 408 MEQLRNELLQERAARQD--LECDKIS--LERQNK----DLKSRIIHL-EGSYRSSKEGLV 458
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ +A + EL ++E+ +++ + + RLE + EL +++++ + + +T K +LS
Sbjct: 459 VQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEH---LSLTDQKDQLS 515
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQI 233
+ ++V++ + I+ + K ++
Sbjct: 516 LRLKAMKRQVEEAEEEIDRLESSKKKL 542
Score = 40.3 bits (90), Expect = 0.016
Identities = 44/197 (22%), Positives = 95/197 (48%), Gaps = 12/197 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELR-QRIEREKADLSVQVIQLSERLEEAEGGAE--SQFEIN 89
L + E ++ ++ L+ E Q +++ K ++ L E +EEA E +
Sbjct: 63 LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNT 122
Query: 90 RKRDTELLKLR-KLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
++D ++R KLL++ + + + + L+++ V Q QI+ L +A+A++ K
Sbjct: 123 SEQDQAGTEMRVKLLQEENEKLQGRSEELERR----VAQLQRQIEDLKGDEAKAKETLKK 178
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
++ E+ +L + +V KE+ LE +EL L++T + ++L +E
Sbjct: 179 YEGEIRQLEEALVHVRKEEKEAVSARRALE---NELEAAQGNLSQTTQEQKQLSEKLKEE 235
Query: 209 NIELVKEVQDLKVNIEN 225
+ E ++++ LK +EN
Sbjct: 236 S-EQKEQLRRLKNEMEN 251
Score = 36.7 bits (81), Expect = 0.19
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 50 ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL- 108
E R E + ++ +L +RLE E + NR+ + ++ +L ++D HL
Sbjct: 447 EGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLS 506
Query: 109 --ESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
+ ++ L K + V + +E+ID+L +K + ++E + Q ++ E L N K+
Sbjct: 507 LTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 565
Query: 167 KITISK 172
+ + K
Sbjct: 566 DLRLKK 571
>AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein.
Length = 1257
Score = 51.6 bits (118), Expect = 6e-06
Identities = 52/221 (23%), Positives = 109/221 (49%), Gaps = 17/221 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------ 83
L +S LE+++ ++ + RE I+R+ A S + SE LE E G +
Sbjct: 199 LERVSALEEELAAANQEIVALREQNVHIQRKMA--SSEGSTESEHLEGMEPGQKVHEKRL 256
Query: 84 SQFEINRKRDT-ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARA 142
S I+ +T ++++L++LLE + E + L + + + +++ + K +
Sbjct: 257 SNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVG-EVEQEAETARKDLIKT 315
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISK---TCERLEITISELHIKIE-EL--NRTIV 196
E+ +K+Q ++ E +AQ E++ + T+ K + +R +I +++ K+E EL I+
Sbjct: 316 EEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAIL 375
Query: 197 DITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQ 236
K R QE +EL +E +Q E + +++++A +
Sbjct: 376 RQMEEKNRQLQERLELAEEKLQQTMRKAETLPEVEAELAQR 416
Score = 35.5 bits (78), Expect = 0.45
Identities = 68/374 (18%), Positives = 144/374 (38%), Gaps = 24/374 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIERE-KADLSVQVIQLSERLEEAEGGAESQF-- 86
L L ++ + L Q L+ R ++R+ + L + L+ L ++G +F
Sbjct: 46 LDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLAGSKGADPPEFAA 105
Query: 87 ---EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
E+N R+ +LL+ + + ++ E T LL+ + E ++ E+ ++T K +A+
Sbjct: 106 LTKELNACRE-QLLEKEEEISELKAERNNTRLLLE--HLECLVSRHERSLRMTVVKRQAQ 162
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
S +EV L A K K ERL +++ + EEL +I +
Sbjct: 163 SP-SGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA--- 218
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L ++N+ + +++ + + E+ +L+ Q Q+ +
Sbjct: 219 -LREQNVHIQRKMASSEGSTESE-HLEGMEPGQKVHEKRLSNGSIDSTDETS----QI-V 271
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
+L+ + LE+++ ++ +L + +G + KY
Sbjct: 272 ELQEL---LEKQNYEMAQMKERLAALSSRVGEVEQE-AETARKDLIKTEEMNTKYQRDIR 327
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
+ +I +EK+ Q E + +K + Q+E N +++
Sbjct: 328 EAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQE 387
Query: 384 RLEETVQLYEQTQR 397
RLE + +QT R
Sbjct: 388 RLELAEEKLQQTMR 401
Score = 33.1 bits (72), Expect = 2.4
Identities = 32/166 (19%), Positives = 74/166 (44%), Gaps = 8/166 (4%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL------EEAEGGAESQF 86
L ++E+K R +Q+ LE E Q+ R+ L +L++R+ EE G E +
Sbjct: 375 LRQMEEKNRQLQERLELAEEKLQQTMRKAETLPEVEAELAQRIAALTKAEETHGNIEERM 434
Query: 87 E-INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + + +L++ + + E L ++ ++ + E++ K + A +E
Sbjct: 435 RHLEGQLEEKNQELQRARQREKMNEEHNKRLSDTVDR-LLTESNERLQLHLKERMAALEE 493
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL 191
K+ E +E +K ++++ E+L + +L ++ L
Sbjct: 494 KNVLIQESETFRKNLEESLHDKESLAEEIEKLRSELDQLKMRTGSL 539
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 51.6 bits (118), Expect = 6e-06
Identities = 73/397 (18%), Positives = 156/397 (39%), Gaps = 17/397 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
SAL + + +++ ++ E+ ++L + ++ +D + L E+L+ + + +
Sbjct: 428 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 487
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
E+ +LR E + E AH L+ Q+ + +++ ++L + +++ + +
Sbjct: 488 DAQREVQRLRSANELLSREKSNLAHSLQVAQQQ-AEELRQEREKLQAAQEELRRQRDRLE 546
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
E + + V +E + E+LE S L ++ E+ + T + L E
Sbjct: 547 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 606
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
E+ + + + + +++ ++ SL Q ++DL +
Sbjct: 607 EVAEALTKAEAGRVELELSMTKLRAE----EASLQDSLSKLSALNESLAQDKLDLNRLVA 662
Query: 271 QLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXX 330
QLEEE A +RQ A E R +
Sbjct: 663 QLEEEKSALQGRQRQ---AEQEATVAREE-QERLEELRLEQEVARQGLEGSLRVAEQAQE 718
Query: 331 TLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTEQLERVNIEIKSRLE 386
L ++ + ++S+LQ ++ L L ++ RE Q++ E LER E ++ +
Sbjct: 719 ALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 778
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
E L Q L + E + +S E + R +K+AL
Sbjct: 779 EHAGLAVQ----LVAAEREGRTLSEEATRLRLEKEAL 811
Score = 47.6 bits (108), Expect = 1e-04
Identities = 60/310 (19%), Positives = 115/310 (37%), Gaps = 22/310 (7%)
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKI 188
+EQ+ +L A + Q EV L + E +++EK ++ + + + EL +
Sbjct: 469 EEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQER 528
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E+L ++ + RL +E + V++ ++ +E Q+ +
Sbjct: 529 EKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVR 588
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXX 308
++ + V L + R++LE + K E +
Sbjct: 589 EALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLS------- 641
Query: 309 XXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQ 368
K S L + +E++KS LQ E+ ARE Q
Sbjct: 642 --------KLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQR----QAEQEATVAREEQ 689
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
+R E+L + LE ++++ EQ Q L + +L + HE + +EQ L+R+
Sbjct: 690 ERLEELRLEQEVARQGLEGSLRVAEQAQEAL---EQQLPTLRHERSQLQEQLAQLSRQLS 746
Query: 429 KMGDDLHDAR 438
+L AR
Sbjct: 747 GREQELEQAR 756
Score = 45.6 bits (103), Expect = 4e-04
Identities = 44/194 (22%), Positives = 83/194 (42%), Gaps = 10/194 (5%)
Query: 31 SALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEE----AEGGAESQ 85
+A LE + +Q L+ E+E L R+E EK +LS ++ L + +E AE +
Sbjct: 906 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 965
Query: 86 FEINRKRDT----ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ T +L+ R L + LE E + + ++ +L +A+
Sbjct: 966 LSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQ 1025
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E+ + EV L Q ++ K++ + + E L + L + L R +++
Sbjct: 1026 REEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE-AQR 1084
Query: 202 KQRLSQENIELVKE 215
K R SQE E+ ++
Sbjct: 1085 KLRESQEGREVQRQ 1098
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/447 (20%), Positives = 172/447 (38%), Gaps = 43/447 (9%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEI 88
++++L + +QD L L + + ++K DL+ V QL E +G AE + +
Sbjct: 625 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV 684
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----------IDFQEQIDQLTK 137
R+ L +LR L ++V + E + + ++ QE + QEQ+ QL++
Sbjct: 685 AREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 743
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISK----------TCERLEITISE---- 183
+ E+E + + E + +E +EK ++K ER T+SE
Sbjct: 744 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 803
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
L ++ E L ++ ++ +L +L E Q L + E L ++A
Sbjct: 804 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET---LTGELAGLRQQIIAT 860
Query: 244 XXXXXXXXXXXXASLHQVEIDLE-SVRVQ--LEEESEARLDLERQLV--KANGEIGHWRS 298
L Q E + + S+R Q EE RL E++ + E +S
Sbjct: 861 QEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQS 920
Query: 299 KFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLE 358
+ + S + + EKQ++ E E + E
Sbjct: 921 QLQREQEELLARLEAEKEELSEEIAALQQERDEGLL-LAESEKQQALSLKESEKTALS-E 978
Query: 359 KANGTARELQKRTEQLERVNIEIKSRLEE---TVQLYEQTQRDLRNKQTELQRV-SHELD 414
K GT L + ++ER + +SR E+ TV RDLR ++ E + E+
Sbjct: 979 KLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVR 1038
Query: 415 KTREQKDALARENKKMGDDLHDARANI 441
+ +EQ L ++ + + R +
Sbjct: 1039 RLQEQARDLGKQRDSCLREAEELRTQL 1065
Score = 40.7 bits (91), Expect = 0.012
Identities = 53/268 (19%), Positives = 104/268 (38%), Gaps = 3/268 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKI-RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
+D E A L RL DK +Q +++RE+ QR+ LS + L+ L+ A
Sbjct: 459 SDSESERRALEEQLQRLRDKTDGAMQAHEDAQREV-QRLRSANELLSREKSNLAHSLQVA 517
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
+ AE + K +LR+ + + E E+ + +E+ Q++QL
Sbjct: 518 QQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERS-HRQLEQLEGK 576
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
++ KE + + + Q + + EK +++ + E EL + + +L +
Sbjct: 577 RSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASL 636
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
+LS N L ++ DL + + KS + +
Sbjct: 637 QDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELR 696
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQL 286
+ E+ + + L +A+ LE+QL
Sbjct: 697 LEQEVARQGLEGSLRVAEQAQEALEQQL 724
Score = 38.7 bits (86), Expect = 0.048
Identities = 68/404 (16%), Positives = 151/404 (37%), Gaps = 10/404 (2%)
Query: 44 QDDLESERELRQRIEREKADL--SVQVIQ--LSERLEEAEGGAESQFEINRKRDTELLKL 99
Q +++ R + + REK++L S+QV Q E +E E +Q E+ R+RD +
Sbjct: 490 QREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQ 549
Query: 100 RKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
++D V E E + L++ + + +E ++ + + +RA ++ QAE E+
Sbjct: 550 EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVE-VREALSRATLQRDMLQAEKAEV 608
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ ++ + + +L + L + +L+ + K L++ +L +E
Sbjct: 609 AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEK 668
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L+ + + SL E E++ QL
Sbjct: 669 SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 728
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
R L+ QL + + ++ R + + + L ++
Sbjct: 729 HERSQLQEQLAQLSRQLSG-REQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQL 787
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQ 396
E++ L E L ++ E G+ E+Q++ QLE ++++ + + E
Sbjct: 788 VAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLT 847
Query: 397 RDLRNKQTELQRVSHELDKTRE-QKDALARENKKMGDDLHDARA 439
+L + ++ + +E L + ++ L + RA
Sbjct: 848 GELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRA 891
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/185 (20%), Positives = 81/185 (43%), Gaps = 2/185 (1%)
Query: 37 EDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
+++ R + L SE R+LR + E A + +V +L E+ + +S + T+
Sbjct: 1005 QEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQ 1064
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L L + + E E L++ + + QE +L ++ KE+ + E
Sbjct: 1065 LRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEA-GELRRSLGEGAKEREALRRSNEE 1123
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L + V+ E+I++ E E ++ L + + ++ + Q + + +E +E
Sbjct: 1124 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1183
Query: 216 VQDLK 220
+Q+L+
Sbjct: 1184 LQELR 1188
Score = 35.5 bits (78), Expect = 0.45
Identities = 36/160 (22%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 27 SADLSALSRLEDKIRLIQDDLES-ERELRQ------RIEREKADLSVQVIQLSERLEEAE 79
+A L+ + +L+D+ RL+Q+ L S +R L Q +ER L + L L++ E
Sbjct: 1729 AAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVE 1788
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E + E +L + L LE E +++ ++V+ EQ + +
Sbjct: 1789 REKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVV--LEQSHSPAQLE 1846
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
A++++ + Q EV E L + T+ + + R +
Sbjct: 1847 VDAQQQQLELQQEV-ERLRSAQAQTERTLEARERAHRQRV 1885
Score = 35.1 bits (77), Expect = 0.59
Identities = 55/286 (19%), Positives = 101/286 (35%), Gaps = 3/286 (1%)
Query: 5 AKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADL 64
A T + T G V A + L + + L S R+ +++
Sbjct: 1602 AGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTAC 1661
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
L ERL+ A + + ++ LR + D+ L+ E L++ +E+
Sbjct: 1662 EHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQL-REV 1720
Query: 125 VIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
+ QE T + + E+ Q + L + + EK + ++ RLE L
Sbjct: 1721 LRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVAL 1780
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
++++ R + RLS E L + + ++ + Q+ +Q
Sbjct: 1781 RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSH 1840
Query: 245 XXXXXXXXXXXASLH-QVEID-LESVRVQLEEESEARLDLERQLVK 288
L Q E++ L S + Q E EAR RQ V+
Sbjct: 1841 SPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVR 1886
Score = 31.1 bits (67), Expect = 9.7
Identities = 36/152 (23%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 4 MAKTSKYTYRSSGGGTTDVNIEYSADLSALSR---LEDKIR-LIQDDLESERELRQR--- 56
+A+TS+ + G +T + + S +AL + L+ ++ ++D + E++L Q+
Sbjct: 230 LARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQ 289
Query: 57 IEREKADLSVQVIQLSERLEEAEGGAESQFEINR--KRDTELLKLRKLLEDVHLESEETA 114
+ +KADLS +V +L ++ E + ++N+ E L+ +L E LE+E+
Sbjct: 290 SDLDKADLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALETEDGE 349
Query: 115 HL---LKKKNQEIVIDFQEQIDQLTKTKARAE 143
L L+ Q ++ D + + QL+ ++ A+
Sbjct: 350 GLQQTLRDLAQAVLSDSESGV-QLSGSERTAD 380
>Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-125H2 on chromosome 22q11-12. ).
Length = 2566
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1750 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1803
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1804 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1863
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1864 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1922
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1923 IQELQLQLEEAKKEKHKLQEQ 1943
Score = 38.7 bits (86), Expect = 0.048
Identities = 69/358 (19%), Positives = 144/358 (40%), Gaps = 25/358 (6%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E + ++ + E N T D +
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQ---QKIQLNDLERNPTGGDEWQMRF 1521
Query: 204 RLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+Q EN L K +Q + +++ + + ++ + H +
Sbjct: 1522 DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLT 1581
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
DLE V LE + +LE++ K + ++ K +
Sbjct: 1582 CDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVTQEN 1633
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L ++ E++ S+L+ +VE+L + G+ + L+ +++
Sbjct: 1634 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1693
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDAR 438
S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D R
Sbjct: 1694 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDVR 1746
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 51.2 bits (117), Expect = 8e-06
Identities = 77/420 (18%), Positives = 167/420 (39%), Gaps = 19/420 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L E + R ++ L+ ++ I ++K L +++ Q+ ++ E + E
Sbjct: 1259 SILQATEQRRRAEENALQ-QKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAA 1317
Query: 91 K----RDTELLKLR-KLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQID-QLTKTKARA 142
K ++ E+ +L+ + E+ E L K +N E +I + Q + ++ TK
Sbjct: 1318 KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTI 1377
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
+ + + + AQ++N+T+E ++S+ +RL+ T+++ E L R DI K
Sbjct: 1378 HQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ---TTENLRRVEEDIQQQK 1434
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
S E+ + Q L+V + V ++++ + + L Q+
Sbjct: 1435 ATGS----EVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQL- 1489
Query: 263 IDLESVRVQLEEESEARLD-LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
ID E+ + E+ ARL ++ L KAN +K + S
Sbjct: 1490 IDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKL-KVQEQELTRLRIDYERVSQE 1548
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
+ ++ QK +++ E+ L + + ++L++ E + R E
Sbjct: 1549 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
++ Q EQ + + +L++ LD +K E +++ ++ R +
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 1668
Score = 49.2 bits (112), Expect = 3e-05
Identities = 81/462 (17%), Positives = 191/462 (41%), Gaps = 46/462 (9%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIERE 60
+A + +Y + + T+ + L+RL D R+ Q+ ++++ R +
Sbjct: 1504 NARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDIT-RFQNS 1562
Query: 61 KADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL------ESEETA 114
+L +Q ++ E L + A +K + EL +R+ L++ + + E A
Sbjct: 1563 LKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQA 1622
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTC 174
++KK++++ D ++Q D L +EK + Q E+ L ++VE + ++ + ++
Sbjct: 1623 SIVKKRSED---DLRQQRDVLDGHL----REKQRTQEELRRLSSEVEALRRQLLQEQESV 1675
Query: 175 ERLEITISELHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENVV 227
++ + IE+ +R++ + + S + L++E++ L +E+++L++ +++
Sbjct: 1676 KQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR 1735
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+S+ S L + DL+ R L +E E ++Q +
Sbjct: 1736 RGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIE---KFQKQAL 1792
Query: 288 KANGEIGHWRSKFX------XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI---NN 338
+A+ I +++ + TL A+
Sbjct: 1793 EASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQR 1852
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE----ETVQLYEQ 394
+E +K ++Q+++ + R+++ E+ ER ++S +E E ++ E+
Sbjct: 1853 LECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEER 1912
Query: 395 TQRDLRNK--------QTELQRVSHELDKTREQKDALARENK 428
+R L + +TE R E+DK R++ RE +
Sbjct: 1913 CRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQ 1954
Score = 44.8 bits (101), Expect = 7e-04
Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 13/175 (7%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLS---ERLEEAEGGAESQ 85
D + L RLED++ + LE+E ++QR+E EK + + Q R EEA ES+
Sbjct: 1825 DKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESE 1884
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
E K + E LR +E + E + ++K ++ + Q Q++ ++R ++E
Sbjct: 1885 RE---KSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLE---TERSRYQRE 1938
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTC---ERLEITISELHIKIEELNRTIVD 197
K + Y + + + + SK R ++T +L+ + + +++T +D
Sbjct: 1939 IDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLY-ECQLIDKTTLD 1992
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 51.2 bits (117), Expect = 8e-06
Identities = 77/420 (18%), Positives = 167/420 (39%), Gaps = 19/420 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L E + R ++ L+ ++ I ++K L +++ Q+ ++ E + E
Sbjct: 140 SILQATEQRRRAEENALQ-QKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAA 198
Query: 91 K----RDTELLKLR-KLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQID-QLTKTKARA 142
K ++ E+ +L+ + E+ E L K +N E +I + Q + ++ TK
Sbjct: 199 KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTI 258
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
+ + + + AQ++N+T+E ++S+ +RL+ T+++ E L R DI K
Sbjct: 259 HQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ---TTENLRRVEEDIQQQK 315
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
S E+ + Q L+V + V ++++ + + L Q+
Sbjct: 316 ATGS----EVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQL- 370
Query: 263 IDLESVRVQLEEESEARLD-LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
ID E+ + E+ ARL ++ L KAN +K + S
Sbjct: 371 IDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKL-KVQEQELTRLRIDYERVSQE 429
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
+ ++ QK +++ E+ L + + ++L++ E + R E
Sbjct: 430 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 489
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
++ Q EQ + + +L++ LD +K E +++ ++ R +
Sbjct: 490 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 549
Score = 49.2 bits (112), Expect = 3e-05
Identities = 81/462 (17%), Positives = 191/462 (41%), Gaps = 46/462 (9%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIERE 60
+A + +Y + + T+ + L+RL D R+ Q+ ++++ R +
Sbjct: 385 NARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDIT-RFQNS 443
Query: 61 KADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL------ESEETA 114
+L +Q ++ E L + A +K + EL +R+ L++ + + E A
Sbjct: 444 LKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQA 503
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTC 174
++KK++++ D ++Q D L +EK + Q E+ L ++VE + ++ + ++
Sbjct: 504 SIVKKRSED---DLRQQRDVLDGHL----REKQRTQEELRRLSSEVEALRRQLLQEQESV 556
Query: 175 ERLEITISELHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENVV 227
++ + IE+ +R++ + + S + L++E++ L +E+++L++ +++
Sbjct: 557 KQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR 616
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+S+ S L + DL+ R L +E E ++Q +
Sbjct: 617 RGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIE---KFQKQAL 673
Query: 288 KANGEIGHWRSKFX------XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI---NN 338
+A+ I +++ + TL A+
Sbjct: 674 EASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQR 733
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE----ETVQLYEQ 394
+E +K ++Q+++ + R+++ E+ ER ++S +E E ++ E+
Sbjct: 734 LECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEER 793
Query: 395 TQRDLRNK--------QTELQRVSHELDKTREQKDALARENK 428
+R L + +TE R E+DK R++ RE +
Sbjct: 794 CRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQ 835
Score = 44.8 bits (101), Expect = 7e-04
Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 13/175 (7%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLS---ERLEEAEGGAESQ 85
D + L RLED++ + LE+E ++QR+E EK + + Q R EEA ES+
Sbjct: 706 DKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESE 765
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
E K + E LR +E + E + ++K ++ + Q Q++ ++R ++E
Sbjct: 766 RE---KSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLE---TERSRYQRE 819
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTC---ERLEITISELHIKIEELNRTIVD 197
K + Y + + + + SK R ++T +L+ + + +++T +D
Sbjct: 820 IDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLY-ECQLIDKTTLD 873
>BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein.
Length = 483
Score = 51.2 bits (117), Expect = 8e-06
Identities = 72/386 (18%), Positives = 145/386 (37%), Gaps = 22/386 (5%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E EL E K L V V L + E G + E R++ + L+ ++ D
Sbjct: 55 ELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 113
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ A +KK + + + + Q+ + K A K+ K QA++ EL +VE +
Sbjct: 114 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 173
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I E + L ++ L + +++ Q+ E+ EV + ++ ++
Sbjct: 174 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 233
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-------SEARL 280
K Q+ + ++ + +ES+ +L E R
Sbjct: 234 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 293
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
LERQ+ + G +G + K + I V
Sbjct: 294 QLERQIQELRGRLG---EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 350
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + RL+ +++ +E+ A +L+ +QLE+ N+ +K + + E+ + +
Sbjct: 351 RAEKRLKE----VVLQVEEERRVADQLR---DQLEKGNLRVK----QLKRQLEEAEEEAS 399
Query: 401 NKQTELQRVSHELDKTREQKDALARE 426
Q +R+ EL+ E +++ RE
Sbjct: 400 RAQAGRRRLQRELEDVTESAESMNRE 425
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELL 97
++ + +L +ER + E + L Q+ +L RL E + GA ++ ++ +++L
Sbjct: 270 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 329
Query: 98 KLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + LE E + L++ K+ +E+V+ +E+ + + R + EK + V
Sbjct: 330 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE--RRVADQLRDQLEKGNLR--VK 385
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
+L Q+E +E RL+ + ++ E +NR + + + +R
Sbjct: 386 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 435
Score = 38.3 bits (85), Expect = 0.064
Identities = 46/264 (17%), Positives = 107/264 (40%), Gaps = 6/264 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
++A +LE ++ ++ + S + ++ ++ + Q+ +L +EE E F N
Sbjct: 121 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 180
Query: 90 RKRDTELLKLRKLLEDVHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ + L L E + L+ E A +++ Q+ + +++ +KA +EK +
Sbjct: 181 RESEKRLKGLE--AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQ 238
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + +L ++E ++ +L + + L ++ S +Q+L ++
Sbjct: 239 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 298
Query: 209 NIELVKEV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
EL + +D + + + + + S+ + + E L+
Sbjct: 299 IQELRGRLGEEDAGARARHKMTI-AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 357
Query: 267 SVRVQLEEESEARLDLERQLVKAN 290
V +Q+EEE L QL K N
Sbjct: 358 EVVLQVEEERRVADQLRDQLEKGN 381
Score = 35.9 bits (79), Expect = 0.34
Identities = 30/160 (18%), Positives = 61/160 (38%)
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ ++ ++ Q L EVE E+ RE +KR + LE + ++ L + +
Sbjct: 149 VKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRAR 208
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
Q Q+D E+ + E+K L ++ ++L + ++N
Sbjct: 209 RQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLL 268
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
+ +AE+GR+ E++ Q L G+
Sbjct: 269 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 308
Score = 31.5 bits (68), Expect = 7.3
Identities = 15/70 (21%), Positives = 37/70 (52%)
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
++LE E+K+++ Q E+ + LR Q +++ + E+++TR ++ + +N++
Sbjct: 125 KKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE 184
Query: 432 DDLHDARANI 441
L A +
Sbjct: 185 KRLKGLEAEV 194
>AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein protein.
Length = 2568
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1752 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1805
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1806 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1865
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1866 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1924
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1925 IQELQLQLEEAKKEKHKLQEQ 1945
Score = 35.9 bits (79), Expect = 0.34
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 30/361 (8%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1406 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1465
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E ++ I++ +L R Q
Sbjct: 1466 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEE-----AQQKIQLNDLERDPTGGADEWQ 1520
Query: 204 R----LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
EN L K +Q + +++ + + ++ + H
Sbjct: 1521 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1580
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ DLE V LE + +LE++ K + ++ K +
Sbjct: 1581 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVT 1632
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L ++ E++ S+L+ +VE+L + G+ + L+
Sbjct: 1633 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1692
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDA 437
+++S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D
Sbjct: 1693 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDV 1747
Query: 438 R 438
R
Sbjct: 1748 R 1748
>AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone RP11-89B2 on chromosome 22. ).
Length = 2566
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1750 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1803
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1804 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1863
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1864 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1922
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1923 IQELQLQLEEAKKEKHKLQEQ 1943
Score = 38.7 bits (86), Expect = 0.048
Identities = 69/358 (19%), Positives = 144/358 (40%), Gaps = 25/358 (6%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E + ++ + E N T D +
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQ---QKIQLNDLERNPTGGDEWQMRF 1521
Query: 204 RLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+Q EN L K +Q + +++ + + ++ + H +
Sbjct: 1522 DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLT 1581
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
DLE V LE + +LE++ K + ++ K +
Sbjct: 1582 CDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVTQEN 1633
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L ++ E++ S+L+ +VE+L + G+ + L+ +++
Sbjct: 1634 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1693
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDAR 438
S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D R
Sbjct: 1694 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDVR 1746
>AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-109D1 on chromosome 22. ).
Length = 2566
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1750 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1803
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1804 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1863
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1864 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1922
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1923 IQELQLQLEEAKKEKHKLQEQ 1943
Score = 38.7 bits (86), Expect = 0.048
Identities = 69/358 (19%), Positives = 144/358 (40%), Gaps = 25/358 (6%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E + ++ + E N T D +
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQ---QKIQLNDLERNPTGGDEWQMRF 1521
Query: 204 RLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+Q EN L K +Q + +++ + + ++ + H +
Sbjct: 1522 DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLT 1581
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
DLE V LE + +LE++ K + ++ K +
Sbjct: 1582 CDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVTQEN 1633
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L ++ E++ S+L+ +VE+L + G+ + L+ +++
Sbjct: 1634 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1693
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDAR 438
S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D R
Sbjct: 1694 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDVR 1746
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 51.2 bits (117), Expect = 8e-06
Identities = 77/420 (18%), Positives = 167/420 (39%), Gaps = 19/420 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L E + R ++ L+ ++ I ++K L +++ Q+ ++ E + E
Sbjct: 1259 SILQATEQRRRAEENALQ-QKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAA 1317
Query: 91 K----RDTELLKLR-KLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQID-QLTKTKARA 142
K ++ E+ +L+ + E+ E L K +N E +I + Q + ++ TK
Sbjct: 1318 KTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTI 1377
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
+ + + + AQ++N+T+E ++S+ +RL+ T+++ E L R DI K
Sbjct: 1378 HQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ---TTENLRRVEEDIQQQK 1434
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
S E+ + Q L+V + V ++++ + + L Q+
Sbjct: 1435 ATGS----EVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQL- 1489
Query: 263 IDLESVRVQLEEESEARLD-LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
ID E+ + E+ ARL ++ L KAN +K + S
Sbjct: 1490 IDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKL-KVQEQELTRLRIDYERVSQE 1548
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEI 381
+ ++ QK +++ E+ L + + ++L++ E + R E
Sbjct: 1549 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 382 KSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
++ Q EQ + + +L++ LD +K E +++ ++ R +
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 1668
Score = 49.2 bits (112), Expect = 3e-05
Identities = 81/462 (17%), Positives = 191/462 (41%), Gaps = 46/462 (9%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLE-DKIRLIQDDLESERELRQRIERE 60
+A + +Y + + T+ + L+RL D R+ Q+ ++++ R +
Sbjct: 1504 NARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDIT-RFQNS 1562
Query: 61 KADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHL------ESEETA 114
+L +Q ++ E L + A +K + EL +R+ L++ + + E A
Sbjct: 1563 LKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQA 1622
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTC 174
++KK++++ D ++Q D L +EK + Q E+ L ++VE + ++ + ++
Sbjct: 1623 SIVKKRSED---DLRQQRDVLDGHL----REKQRTQEELRRLSSEVEALRRQLLQEQESV 1675
Query: 175 ERLEITISELHIKIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENVV 227
++ + IE+ +R++ + + S + L++E++ L +E+++L++ +++
Sbjct: 1676 KQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLR 1735
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+S+ S L + DL+ R L +E E ++Q +
Sbjct: 1736 RGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIE---KFQKQAL 1792
Query: 288 KANGEIGHWRSKFX------XXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI---NN 338
+A+ I +++ + TL A+
Sbjct: 1793 EASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQR 1852
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE----ETVQLYEQ 394
+E +K ++Q+++ + R+++ E+ ER ++S +E E ++ E+
Sbjct: 1853 LECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEER 1912
Query: 395 TQRDLRNK--------QTELQRVSHELDKTREQKDALARENK 428
+R L + +TE R E+DK R++ RE +
Sbjct: 1913 CRRKLEDSTRETQSQLETERSRYQREIDKLRQRPYGSHRETQ 1954
Score = 44.8 bits (101), Expect = 7e-04
Identities = 42/175 (24%), Positives = 83/175 (47%), Gaps = 13/175 (7%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLS---ERLEEAEGGAESQ 85
D + L RLED++ + LE+E ++QR+E EK + + Q R EEA ES+
Sbjct: 1825 DKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESE 1884
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
E K + E LR +E + E + ++K ++ + Q Q++ ++R ++E
Sbjct: 1885 RE---KSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLE---TERSRYQRE 1938
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTC---ERLEITISELHIKIEELNRTIVD 197
K + Y + + + + SK R ++T +L+ + + +++T +D
Sbjct: 1939 IDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTAMQLY-ECQLIDKTTLD 1992
>AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA sequence
from clone CTA-407F11 on chromosome 22q12. ).
Length = 2566
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1750 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1803
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1804 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1863
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1864 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1922
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1923 IQELQLQLEEAKKEKHKLQEQ 1943
Score = 38.7 bits (86), Expect = 0.048
Identities = 69/358 (19%), Positives = 144/358 (40%), Gaps = 25/358 (6%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E + ++ + E N T D +
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQ---QKIQLNDLERNPTGGDEWQMRF 1521
Query: 204 RLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
+Q EN L K +Q + +++ + + ++ + H +
Sbjct: 1522 DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLT 1581
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
DLE V LE + +LE++ K + ++ K +
Sbjct: 1582 CDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVTQEN 1633
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L ++ E++ S+L+ +VE+L + G+ + L+ +++
Sbjct: 1634 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1693
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDAR 438
S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D R
Sbjct: 1694 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDVR 1746
>AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens
cDNA FLJ13881 fis, clone THYRO1001458, moderately
similar to MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 545
Score = 51.2 bits (117), Expect = 8e-06
Identities = 72/386 (18%), Positives = 145/386 (37%), Gaps = 22/386 (5%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E EL E K L V V L + E G + E R++ + L+ ++ D
Sbjct: 117 ELEDELTAA-EDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE 175
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
+ A +KK + + + + Q+ + K A K+ K QA++ EL +VE +
Sbjct: 176 RKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSR 235
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I E + L ++ L + +++ Q+ E+ EV + ++ ++
Sbjct: 236 EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAIL 295
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-------SEARL 280
K Q+ + ++ + +ES+ +L E R
Sbjct: 296 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 355
Query: 281 DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVE 340
LERQ+ + G +G + K + I V
Sbjct: 356 QLERQIQELRGRLG---EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVR 412
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ + RL+ +++ +E+ A +L+ +QLE+ N+ +K + + E+ + +
Sbjct: 413 RAEKRLKE----VVLQVEEERRVADQLR---DQLEKGNLRVK----QLKRQLEEAEEEAS 461
Query: 401 NKQTELQRVSHELDKTREQKDALARE 426
Q +R+ EL+ E +++ RE
Sbjct: 462 RAQAGRRRLQRELEDVTESAESMNRE 487
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/170 (20%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN-RKRDTELL 97
++ + +L +ER + E + L Q+ +L RL E + GA ++ ++ +++L
Sbjct: 332 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 391
Query: 98 KLRKLLEDVHLESEETAHLLK---KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ + LE E + L++ K+ +E+V+ +E+ + + R + EK + V
Sbjct: 392 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE--RRVADQLRDQLEKGNLR--VK 447
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
+L Q+E +E RL+ + ++ E +NR + + + +R
Sbjct: 448 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR 497
Score = 38.3 bits (85), Expect = 0.064
Identities = 46/264 (17%), Positives = 107/264 (40%), Gaps = 6/264 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
++A +LE ++ ++ + S + ++ ++ + Q+ +L +EE E F N
Sbjct: 183 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 242
Query: 90 RKRDTELLKLRKLLEDVHLESEETA-HLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
R+ + L L E + L+ E A +++ Q+ + +++ +KA +EK +
Sbjct: 243 RESEKRLKGLE--AEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQ 300
Query: 149 FQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + +L ++E ++ +L + + L ++ S +Q+L ++
Sbjct: 301 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 360
Query: 209 NIELVKEV--QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLE 266
EL + +D + + + + + S+ + + E L+
Sbjct: 361 IQELRGRLGEEDAGARARHKMTI-AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLK 419
Query: 267 SVRVQLEEESEARLDLERQLVKAN 290
V +Q+EEE L QL K N
Sbjct: 420 EVVLQVEEERRVADQLRDQLEKGN 443
Score = 35.9 bits (79), Expect = 0.34
Identities = 30/160 (18%), Positives = 61/160 (38%)
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY 392
+ ++ ++ Q L EVE E+ RE +KR + LE + ++ L + +
Sbjct: 211 VKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRAR 270
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXX 452
Q Q+D E+ + E+K L ++ ++L + ++N
Sbjct: 271 RQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLL 330
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRLTAEFGQ 492
+ +AE+GR+ E++ Q L G+
Sbjct: 331 LQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGE 370
Score = 35.1 bits (77), Expect = 0.59
Identities = 29/110 (26%), Positives = 42/110 (38%), Gaps = 1/110 (0%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E R+R E E + + + L+ LEE + E NR EL L +DV
Sbjct: 36 EERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVH 95
Query: 112 ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVE 161
E + Q D + Q+ +L AE K + + V L Q E
Sbjct: 96 ELERACRVAEQ-AANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHE 144
Score = 34.7 bits (76), Expect = 0.79
Identities = 16/80 (20%), Positives = 43/80 (53%)
Query: 355 IDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD 414
+DLE+ L+K+ + +++ E K+ + V+ E+ + + R ++ ++ L+
Sbjct: 1 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALE 60
Query: 415 KTREQKDALARENKKMGDDL 434
+ +E ++ L R+N+ + +L
Sbjct: 61 EEQEAREELERQNRALRAEL 80
Score = 31.5 bits (68), Expect = 7.3
Identities = 15/70 (21%), Positives = 37/70 (52%)
Query: 372 EQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
++LE E+K+++ Q E+ + LR Q +++ + E+++TR ++ + +N++
Sbjct: 187 KKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE 246
Query: 432 DDLHDARANI 441
L A +
Sbjct: 247 KRLKGLEAEV 256
>AK002047-1|BAA92054.1| 422|Homo sapiens protein ( Homo sapiens
cDNA FLJ11185 fis, clone PLACE1007511, weakly similar to
KERATIN, TYPE I CYTOSKELETAL 19. ).
Length = 422
Score = 51.2 bits (117), Expect = 8e-06
Identities = 51/219 (23%), Positives = 108/219 (49%), Gaps = 8/219 (3%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE--A 78
D N++Y + S LE ++ ++ L++ + +E+E + ++I + E E+
Sbjct: 156 DFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKEHHEQEME 215
Query: 79 EGGAESQFEINRKRDTELLK-LRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
E S F +N K DT + L K+LED+ E E ++KKK++++ ++EQ +++
Sbjct: 216 EHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYE---LIIKKKHRDLDTWYKEQSAAMSQ 272
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
A +S+ Q +++EL + + + T LE +SE + + + +
Sbjct: 273 EAASPATVQSR-QGDIHELKRTFQALEIDLQAQYSTKSALENMLSETQSRYSCKLQDMQE 331
Query: 198 ITSH-KQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
I SH ++ L+Q EL ++ + +V + +L+ +I +
Sbjct: 332 IISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEITT 370
>AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain protein.
Length = 2567
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1751 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1804
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1805 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1923
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1924 IQELQLQLEEAKKEKHKLQEQ 1944
Score = 36.3 bits (80), Expect = 0.26
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 30/361 (8%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E ++ I++ +L R Q
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEE-----AQQKIQLNDLERNPTGGADEWQ 1519
Query: 204 R----LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
EN L K +Q + +++ + + ++ + H
Sbjct: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1579
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ DLE V LE + +LE++ K + ++ K +
Sbjct: 1580 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVT 1631
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L ++ E++ S+L+ +VE+L + G+ + L+
Sbjct: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDA 437
+++S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D
Sbjct: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDV 1746
Query: 438 R 438
R
Sbjct: 1747 R 1747
>AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain protein.
Length = 2567
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1751 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1804
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1805 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1923
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1924 IQELQLQLEEAKKEKHKLQEQ 1944
Score = 36.3 bits (80), Expect = 0.26
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 30/361 (8%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E ++ I++ +L R Q
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEE-----AQQKIQLNDLERNPTGGADEWQ 1519
Query: 204 R----LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
EN L K +Q + +++ + + ++ + H
Sbjct: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1579
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ DLE V LE + +LE++ K + ++ K +
Sbjct: 1580 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVT 1631
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L ++ E++ S+L+ +VE+L + G+ + L+
Sbjct: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDA 437
+++S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D
Sbjct: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDV 1746
Query: 438 R 438
R
Sbjct: 1747 R 1747
>AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein.
Length = 2567
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1751 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1804
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1805 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1923
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1924 IQELQLQLEEAKKEKHKLQEQ 1944
Score = 36.3 bits (80), Expect = 0.26
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 30/361 (8%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E ++ I++ +L R Q
Sbjct: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEE-----AQQKIQLNDLERNPTGGADEWQ 1519
Query: 204 R----LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
EN L K +Q + +++ + + ++ + H
Sbjct: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1579
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ DLE V LE + +LE++ K + ++ K +
Sbjct: 1580 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVT 1631
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L ++ E++ S+L+ +VE+L + G+ + L+
Sbjct: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDA 437
+++S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D
Sbjct: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDV 1746
Query: 438 R 438
R
Sbjct: 1747 R 1747
>AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein.
Length = 2080
Score = 51.2 bits (117), Expect = 8e-06
Identities = 40/201 (19%), Positives = 94/201 (46%), Gaps = 8/201 (3%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ ++ ++ LE E E +Q + EK DL + L +++ + F++ ++ +L
Sbjct: 1264 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD------FDVEKRLRRDL 1317
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
+ LL DV L ++E + Q++Q A K + A++ +
Sbjct: 1318 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1377
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI-TSHKQRLSQENIELVKE 215
+++EN+T+ K + + RL+ ++L +I+E + ++ HK ++Q + + +
Sbjct: 1378 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD-IGQ 1436
Query: 216 VQDLKVNIENVVYLKSQIASQ 236
+Q+L++ +E K ++ Q
Sbjct: 1437 IQELQLQLEEAKKEKHKLQEQ 1457
Score = 36.3 bits (80), Expect = 0.26
Identities = 68/361 (18%), Positives = 142/361 (39%), Gaps = 30/361 (8%)
Query: 90 RKRDTELLKLRKLLED---VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R ++ EL LR+ LE + E + LL+ K ++ D ++ + E E+
Sbjct: 918 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 977
Query: 147 S-KFQA--EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ + QA EV EL ++ E V K+ ++K E ++ I++ +L R Q
Sbjct: 978 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEE-----AQQKIQLNDLERNPTGGADEWQ 1032
Query: 204 R----LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
EN L K +Q + +++ + + ++ + H
Sbjct: 1033 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1092
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ DLE V LE + +LE++ K + ++ K +
Sbjct: 1093 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQ--------ALGESVFEKGLREKVT 1144
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L ++ E++ S+L+ +VE+L + G+ + L+
Sbjct: 1145 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1204
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENKKMGDDLHDA 437
+++S E ++ Q + ++ + QR E+++ ++ QKD RE+++ ++L D
Sbjct: 1205 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD---REDQE--EELEDV 1259
Query: 438 R 438
R
Sbjct: 1260 R 1260
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 51.2 bits (117), Expect = 8e-06
Identities = 60/195 (30%), Positives = 90/195 (46%), Gaps = 24/195 (12%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 807 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 866 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELNL---QRINPTTVKMKSSVFDEDKT 922
Query: 149 FQAEVYELLAQVEN----------VTK-EKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E+ VE VTK EK+ +S+ L + + H +I LN +
Sbjct: 923 FVAETLEMGEVVEKDTTELMENLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKS 982
Query: 198 ITSHKQRLSQENIEL 212
+ K+++S EL
Sbjct: 983 LKQEKEQVSLRCREL 997
Score = 50.8 bits (116), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 2179 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 2235
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 2236 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 2295
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 2296 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 2355
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 2356 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 2412
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 2413 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 2469
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 2470 ENQTYFKSFEENGKGSII----NLETRLRQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2525
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 2526 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2585
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 2586 ED-ELGSDI 2593
Score = 44.8 bits (101), Expect = 7e-04
Identities = 89/414 (21%), Positives = 178/414 (42%), Gaps = 48/414 (11%)
Query: 33 LSRLEDKIRLIQDDLESER-ELRQRIEREKADLSVQVIQLSERLEEAE--GGAESQFEIN 89
L L+++I ++++ + EL ++E+ S ++ QL +EE + +SQFE +
Sbjct: 359 LGELQEQIVQKNQEIKNMKLELTNSKQKERQS-SEEIKQLMGTVEELQKRNHKDSQFETD 417
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+ E RKL E + E +E Q+IV QE I Q A+ E+ K++
Sbjct: 418 IVQRMEQETQRKL-EQLRAELDEMY------GQQIVQMKQELIRQ---HMAQMEEIKTRH 467
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+ E+ L N+T + I + + + I+EL+IK+++ N S K++L +E
Sbjct: 468 KGEMENALRSYSNITVNEDQI----KLMNVAINELNIKLQDTN-------SQKEKLKEEL 516
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+++E L+ +E++V S Q SL V E ++
Sbjct: 517 GLILEEKCALQRQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTV----EDLK 572
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
++ SE+R +LE +K E+ +++ K S
Sbjct: 573 AEIVSASESRKELE---LKHEAEVTNYKIKLEMLEKEKNAVLDRMAE--SQEAELERLST 627
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDL---------EKANGTARELQKRTE--QLERVN 378
L + + K K L+ E + I L ++ +G E+ ++ E Q E+ N
Sbjct: 628 QLLFSHEEELSKLKEDLEIEHRISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDN 687
Query: 379 IEIK-SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMG 431
+ K ++L + + Q+ L N ++E ++ ++++ +++ + L +E K+ G
Sbjct: 688 LITKQNQLILEISKLKDLQQSLVNSKSE--EMTLQINELQKEIEILRQEEKEKG 739
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 3193 DEVHLLNDTLASEHKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 3252
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 3253 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLQSQKVRIREMSSTLDRE 3311
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 3312 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 3368
Query: 213 VKEVQ 217
++++
Sbjct: 3369 RQQME 3373
Score = 40.7 bits (91), Expect = 0.012
Identities = 56/271 (20%), Positives = 113/271 (41%), Gaps = 13/271 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 708 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 826
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
E +L Q E + K++ T S + E+ EL + L + D+ K +
Sbjct: 827 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 886
Query: 207 QENIELVKEVQDLKVNIENV----VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
E +K + + ++N++ + V +KS + + L +
Sbjct: 887 LEYKSKLKALNE-ELNLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME-- 943
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEI 293
+LE + + E S+ DL QL + +GEI
Sbjct: 944 -NLEVTKREKLELSQRLSDLSEQLKQKHGEI 973
Score = 38.7 bits (86), Expect = 0.048
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 1996
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 1997 ETEKLMKEKL--EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 2054
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 2055 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 2113
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 2114 LANHLKEKTD 2123
Score = 37.5 bits (83), Expect = 0.11
Identities = 68/373 (18%), Positives = 149/373 (39%), Gaps = 22/373 (5%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + A+ + EI + E+ + +
Sbjct: 423 EQETQRKLEQLRAELDEMYGQQIVQMKQELIR-QHMAQME-EIKTRHKGEMENALRSYSN 480
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++
Sbjct: 481 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSF 539
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+ +T E ++E H + + +I S + + ++ EV + K+
Sbjct: 540 SRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIK 599
Query: 223 IENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX--ASLHQVEIDLE-SVRVQLEE-ESEA 278
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 600 LEMLEKEKNAVLDRMAESQEAELERLSTQLLFSHEEELSKLKEDLEIEHRISIEKLKDNL 659
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
+ ++Q+ E+ K + +K
Sbjct: 660 GIHYKQQIDGLQNEMSQ---KIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEE 716
Query: 339 VEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 717 MTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEA 775
Query: 395 TQRDLRNKQTELQ 407
L++++ L+
Sbjct: 776 ENSILKDEKKTLE 788
Score = 36.7 bits (81), Expect = 0.19
Identities = 70/372 (18%), Positives = 143/372 (38%), Gaps = 24/372 (6%)
Query: 45 DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLE 104
+ L+ + ELR+R+ E ++LS+ +G A+ + R+ + + +L +
Sbjct: 1891 ESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDVIDRLEQ 1950
Query: 105 DVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVT 164
++ S L ++ Q QE+ + L++ K + E + + LL + E +
Sbjct: 1951 ELLCASNRLQELEAEQQQ-----IQEERELLSRQKEAMKAEAGPVEQQ---LLQETEKLM 2002
Query: 165 KEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
KEK+ + E++ +L +++ L +D+ R + +E K + + + +
Sbjct: 2003 KEKLEVQCQAEKVR---DDLQKQVKALE---IDVEEQVSRFIE--LEQEKNTELMDLRQQ 2054
Query: 225 NVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV-RVQLEEESEARLDLE 283
N L+ Q+ + ++E L+ V R Q E + R ++E
Sbjct: 2055 NQA-LEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTR-EVE 2112
Query: 284 RQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA---KINNVE 340
QL E S+ + L+ K
Sbjct: 2113 -QLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELVQALLVEDRKHFGAV 2171
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
+ K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 2172 EAKPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKK 2230
Query: 401 NKQTELQRVSHE 412
T LQ + E
Sbjct: 2231 ESTTRLQELEQE 2242
Score = 35.5 bits (78), Expect = 0.45
Identities = 59/336 (17%), Positives = 127/336 (37%), Gaps = 19/336 (5%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 1840 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 1899
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 1900 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDVIDRLEQELLCASNRL 1959
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 1960 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAE- 2013
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 2014 KVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 2073
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 2074 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 2133
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
Q QRD++ + E++++ + RE AL E++K
Sbjct: 2134 QLQRDIQERNEEIEKLEF---RVRELVQALLVEDRK 2166
Score = 35.1 bits (77), Expect = 0.59
Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 3122 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 3181
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E+KK
Sbjct: 3182 EAFRLEVKDKTDEVHLLNDTLASEHKK 3208
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 2588 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 2644
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 2645 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 2702
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 2703 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2752
Score = 31.5 bits (68), Expect = 7.3
Identities = 17/73 (23%), Positives = 36/73 (49%)
Query: 357 LEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKT 416
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 3344 LEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSK 3403
Query: 417 REQKDALARENKK 429
E E ++
Sbjct: 3404 VEDLQRQLEEKRQ 3416
>BC131590-1|AAI31591.1| 754|Homo sapiens EPS15L1 protein protein.
Length = 754
Score = 50.8 bits (116), Expect = 1e-05
Identities = 41/177 (23%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
+ S +++ L R +K L QD E E +RQ+ E +L + + + L+E E +
Sbjct: 388 DISQEIAQLQR--EKYSLEQDIREKEEAIRQKTS-EVQELQNDLDRETSSLQELEAQKQD 444
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHL---LKKKNQEIVIDFQEQIDQLTKTKA- 140
+ + D + KLR +L DV + ++ + LK + Q D + Q D L + K+
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSE 504
Query: 141 --RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
R ++E+++ + + Q+E + K + + +S+LH +E +R++
Sbjct: 505 LNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSL 561
Score = 35.5 bits (78), Expect = 0.45
Identities = 35/176 (19%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E D+S ++ QL E + E R++ +E+ +L+ L+ ET+ L +
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLD------RETSSLQE 437
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
+ Q+ D Q+++D++ + KA+ S + + + + + ++ K I L+
Sbjct: 438 LEAQKQ--DAQDRLDEMDQQKAKLRDMLSDVRQKCQD---ETQMISSLKTQIQSQESDLK 492
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIA 234
+L+ ELNR + T +Q + ++L ++ LK + + +S+++
Sbjct: 493 SQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLS 548
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+DV + + +S L+ +I+ + DL+S+ + R + E L + QL + ++
Sbjct: 464 SDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGR 523
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
E+ + + E+ + R L +H ES + AH
Sbjct: 524 VQLETIIKSLKSTQDEINQARSKLSQLH-ESRQEAH 558
Score = 31.9 bits (69), Expect = 5.5
Identities = 17/83 (20%), Positives = 39/83 (46%)
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDK 415
+L+ + +LQ+ LE+ E + + + ++ Q DL + + LQ + +
Sbjct: 385 ELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQD 444
Query: 416 TREQKDALARENKKMGDDLHDAR 438
+++ D + ++ K+ D L D R
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVR 467
>AF110265-1|AAF21930.1| 864|Homo sapiens epidermal growth factor
receptor substrate EPS15R protein.
Length = 864
Score = 50.8 bits (116), Expect = 1e-05
Identities = 41/177 (23%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
+ S +++ L R +K L QD E E +RQ+ E +L + + + L+E E +
Sbjct: 388 DISQEIAQLQR--EKYSLEQDIREKEEAIRQKTS-EVQELQNDLDRETSSLQELEAQKQD 444
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHL---LKKKNQEIVIDFQEQIDQLTKTKA- 140
+ + D + KLR +L DV + ++ + LK + Q D + Q D L + K+
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSE 504
Query: 141 --RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
R ++E+++ + + Q+E + K + + +S+LH +E +R++
Sbjct: 505 LNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSL 561
Score = 35.5 bits (78), Expect = 0.45
Identities = 35/176 (19%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E D+S ++ QL E + E R++ +E+ +L+ L+ ET+ L +
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLD------RETSSLQE 437
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
+ Q+ D Q+++D++ + KA+ S + + + + + ++ K I L+
Sbjct: 438 LEAQKQ--DAQDRLDEMDQQKAKLRDMLSDVRQKCQD---ETQMISSLKTQIQSQESDLK 492
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIA 234
+L+ ELNR + T +Q + ++L ++ LK + + +S+++
Sbjct: 493 SQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLS 548
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+DV + + +S L+ +I+ + DL+S+ + R + E L + QL + ++
Sbjct: 464 SDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGR 523
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
E+ + + E+ + R L +H ES + AH
Sbjct: 524 VQLETIIKSLKSTQDEINQARSKLSQLH-ESRQEAH 558
Score = 31.9 bits (69), Expect = 5.5
Identities = 17/83 (20%), Positives = 39/83 (46%)
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDK 415
+L+ + +LQ+ LE+ E + + + ++ Q DL + + LQ + +
Sbjct: 385 ELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQD 444
Query: 416 TREQKDALARENKKMGDDLHDAR 438
+++ D + ++ K+ D L D R
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVR 467
>AB015346-1|BAA88118.1| 864|Homo sapiens Eps15R protein.
Length = 864
Score = 50.8 bits (116), Expect = 1e-05
Identities = 41/177 (23%), Positives = 83/177 (46%), Gaps = 9/177 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
+ S +++ L R +K L QD E E +RQ+ E +L + + + L+E E +
Sbjct: 388 DISQEIAQLQR--EKYSLEQDIREKEEAIRQKTS-EVQELQNDLDRETSSLQELEAQKQD 444
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHL---LKKKNQEIVIDFQEQIDQLTKTKA- 140
+ + D + KLR +L DV + ++ + LK + Q D + Q D L + K+
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSE 504
Query: 141 --RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTI 195
R ++E+++ + + Q+E + K + + +S+LH +E +R++
Sbjct: 505 LNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLSQLHESRQEAHRSL 561
Score = 35.5 bits (78), Expect = 0.45
Identities = 35/176 (19%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E D+S ++ QL E + E R++ +E+ +L+ L+ ET+ L +
Sbjct: 384 KELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLD------RETSSLQE 437
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
+ Q+ D Q+++D++ + KA+ S + + + + + ++ K I L+
Sbjct: 438 LEAQKQ--DAQDRLDEMDQQKAKLRDMLSDVRQKCQD---ETQMISSLKTQIQSQESDLK 492
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIA 234
+L+ ELNR + T +Q + ++L ++ LK + + +S+++
Sbjct: 493 SQEDDLNRAKSELNRLQQEETQLEQSIQAGRVQLETIIKSLKSTQDEINQARSKLS 548
Score = 32.7 bits (71), Expect = 3.2
Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+DV + + +S L+ +I+ + DL+S+ + R + E L + QL + ++
Sbjct: 464 SDVRQKCQDETQMISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGR 523
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
E+ + + E+ + R L +H ES + AH
Sbjct: 524 VQLETIIKSLKSTQDEINQARSKLSQLH-ESRQEAH 558
Score = 31.9 bits (69), Expect = 5.5
Identities = 17/83 (20%), Positives = 39/83 (46%)
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDK 415
+L+ + +LQ+ LE+ E + + + ++ Q DL + + LQ + +
Sbjct: 385 ELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQD 444
Query: 416 TREQKDALARENKKMGDDLHDAR 438
+++ D + ++ K+ D L D R
Sbjct: 445 AQDRLDEMDQQKAKLRDMLSDVR 467
>BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein.
Length = 1236
Score = 50.4 bits (115), Expect = 1e-05
Identities = 51/221 (23%), Positives = 109/221 (49%), Gaps = 17/221 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------ 83
L +S LE+++ ++ + RE I+R+ A S + SE LE E G +
Sbjct: 199 LERVSALEEELAAANQEIVALREQNVHIQRKMA--SSEGSTESEHLEGMEPGQKVHEKRL 256
Query: 84 SQFEINRKRDT-ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARA 142
S I+ +T ++++L++LLE + E + L + + + +++ + K +
Sbjct: 257 SNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVG-EVEQEAETARKDLIKT 315
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISK---TCERLEITISELHIKIE-EL--NRTIV 196
E+ +K+Q ++ E +AQ E++ + T+ K + +R +I +++ K+E EL I+
Sbjct: 316 EEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAIL 375
Query: 197 DITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQ 236
K R QE +EL ++ +Q E + +++++A +
Sbjct: 376 RQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQR 416
Score = 37.5 bits (83), Expect = 0.11
Identities = 76/416 (18%), Positives = 158/416 (37%), Gaps = 27/416 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIERE-KADLSVQVIQLSERLEEAEGGAESQF-- 86
L L ++ + L Q L+ R ++R+ + L + L+ L ++G +F
Sbjct: 46 LDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLAGSKGADPPEFAA 105
Query: 87 ---EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
E+N R+ +LL+ + + ++ E T LL+ + E ++ E+ ++T K +A+
Sbjct: 106 LTKELNACRE-QLLEKEEEISELKAERNNTRLLLE--HLECLVSRHERSLRMTVVKRQAQ 162
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
S +EV L A K K ERL +++ + EEL +I +
Sbjct: 163 SP-SGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA--- 218
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L ++N+ + +++ + + E+ +L+ Q Q+ +
Sbjct: 219 -LREQNVHIQRKMASSEGSTESE-HLEGMEPGQKVHEKRLSNGSIDSTDETS----QI-V 271
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
+L+ + LE+++ ++ +L + +G + KY
Sbjct: 272 ELQEL---LEKQNYEMAQMKERLAALSSRVGEVEQE-AETARKDLIKTEEMNTKYQRDIR 327
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
+ +I +EK+ Q E + +K + Q+E N +++
Sbjct: 328 EAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQE 387
Query: 384 RLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
RLE Q +QT R L + EL + L K E+ + + + L +
Sbjct: 388 RLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEE 443
>AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A
protein.
Length = 1016
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 544 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 600
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 601 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 660
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 661 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 720
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 721 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 777
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 778 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 834
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 835 ENQTYFRSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 890
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 891 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 950
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 951 ED-ELGSDI 958
Score = 38.7 bits (86), Expect = 0.048
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 302 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 353
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 354 ETEKLMKEKL--EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 411
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 412 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 470
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 471 LANHLKEKTD 480
Score = 33.5 bits (73), Expect = 1.8
Identities = 57/342 (16%), Positives = 127/342 (37%), Gaps = 16/342 (4%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 197 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 256
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 257 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRL 316
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 317 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAE- 370
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 371 KVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 430
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 431 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 490
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
Q QRD++ + E++++ + + + A +K+ D H
Sbjct: 491 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKH 532
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 539 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 597
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 598 TTRLQELEQE 607
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 50.4 bits (115), Expect = 1e-05
Identities = 85/424 (20%), Positives = 178/424 (41%), Gaps = 28/424 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L L++K+R ++++ + +E + + + +++ Q+ + + + + E E++ EI R
Sbjct: 296 SELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILR 355
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ + + + R+L V ++E L QEI + ++ L K ++ ++ F
Sbjct: 356 DKFSLMNENRELKVRVAAQNER----LDLCQQEIESS-RVELRSLEKIISQLPLKRELFG 410
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKI----EELNRTIVDITSHK--QR 204
+ Y Q+ + + ++ CE ++ ISEL IK+ E+ + ++T+++ Q
Sbjct: 411 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQS 470
Query: 205 L-----SQENIELVK-EVQDLKVNIENVVYLKSQIA-SQXXXXXXXXXXXXXXXXXXXAS 257
L SQE+ +L E + +K+ V +K Q +
Sbjct: 471 LITCNDSQESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTK 530
Query: 258 LHQVEIDLESVRVQL-EEESEARLDLERQLVKA--NGEIGHWRSKFXXXXXXXXXXXXXX 314
L Q+E + ++V + S+ +L E L KA + ++ +K
Sbjct: 531 LIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEK 590
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE-Q 373
YS L+ K + ++ + +E E + + EKA E K E Q
Sbjct: 591 IVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQ 650
Query: 374 LERVNIEIKSR---LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ER+ +++ + +E + Q+D+ KQ L+ + L E K + +EN K
Sbjct: 651 IERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLL---TESKGEMKKENMKK 707
Query: 431 GDDL 434
+ L
Sbjct: 708 DEAL 711
Score = 48.8 bits (111), Expect = 5e-05
Identities = 84/411 (20%), Positives = 157/411 (38%), Gaps = 22/411 (5%)
Query: 30 LSALSRLEDKI----RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA-EGGAES 84
L+ +LE+KI + + E E+EL ++ E+ ++ L + E++ A E +
Sbjct: 581 LTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRS-LETNINTEHEKICLAFEKAKKI 639
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
E +++ + ++ +L LE + +E + Q+I+ Q ++ L + ++
Sbjct: 640 HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKG 698
Query: 145 EKSKFQAEVYELLAQVEN-VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
E K + E L ++N V++E I + + LEI EL + + +L +
Sbjct: 699 EMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLK 758
Query: 204 RLSQENIELVKEVQ----DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
+ S+E L KE++ L+ E V L+ + Q
Sbjct: 759 KKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEK 818
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
QV + ++ Q E +E +E + A E R K +Y
Sbjct: 819 QVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMD-QYK 877
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L N S+L ++ +LEK +EL+K E
Sbjct: 878 EELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE---- 933
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENK 428
+ L E +Q E + +L+N EL+ +L + R+ QK L+ E K
Sbjct: 934 ---TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 981
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/270 (18%), Positives = 117/270 (43%), Gaps = 20/270 (7%)
Query: 34 SRLEDKIRLIQDDLESEREL---RQRIEREKADLSVQVIQLS-ERLEEAEGGAES-QFEI 88
++LE ++ ++ +L+ +RE + R EK + + L +++ E G A + E+
Sbjct: 814 TKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 873
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID-FQEQIDQLTKTKARAEKEKS 147
++ ++ EL K+ K E +HL+ + + ++++D + ++++ T EK +
Sbjct: 874 DQYKE-ELSKMEK--EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH 930
Query: 148 KFQAEVYELL-------AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ E+ E L +++N E + + + L + + + +EE TI D+T+
Sbjct: 931 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 990
Query: 201 H----KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K + + EL++ Q LK + +Q+
Sbjct: 991 ELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG 1050
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQL 286
+L + E++L+ Q+E ++ + + QL
Sbjct: 1051 TLEKSELELKECNKQIESLNDKLQNAKEQL 1080
Score = 34.3 bits (75), Expect = 1.0
Identities = 44/220 (20%), Positives = 96/220 (43%), Gaps = 28/220 (12%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINR 90
+ L DK++ ++ L + + + E+E + L ++ + +R++E E + Q+ +
Sbjct: 1066 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 1125
Query: 91 KRDT-----ELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTK------ 137
++ EL R+ +++ H E E H + +EI + E + QL+K
Sbjct: 1126 YKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHG 1185
Query: 138 ---------TKARAEKEKSKFQAEVYELLAQVENVTK----EKITISKTCERLEITISEL 184
+K R +++ QAE+ +L A+VE++ + E I+ + + +I+
Sbjct: 1186 NHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQ 1245
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+++LN + + L ++VQD IE
Sbjct: 1246 KSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIE 1285
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 2188 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 2244
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 2245 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 2304
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 2305 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 2364
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 2365 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 2421
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 2422 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 2478
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 2479 ENQTYFKSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2534
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 2535 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2594
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 2595 ED-ELGSDI 2602
Score = 46.4 bits (105), Expect = 2e-04
Identities = 62/218 (28%), Positives = 97/218 (44%), Gaps = 26/218 (11%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG---AESQFEINRKRDT 94
D I+ D E+E+ IE E DL Q IQL+E +E+ AE FE+N +
Sbjct: 807 DSIKSKSKDSVWEKEIEILIE-ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Query: 95 E----LLKLRKLLEDVHLESE-ETAHLLKKKNQEIVIDFQEQIDQLT-KTKARAEKEKSK 148
E LLK++ LED + E E LK N+E+ + ++I+ T K K+ E
Sbjct: 866 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHL---QRINPTTVKMKSSVFDEDKT 922
Query: 149 FQAEVYE-----------LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
F AE E L+ ++E +EK+ +S+ L + +I LN +
Sbjct: 923 FVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQRLSDLSEQLKPKPGEISFLNEEVKS 982
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
+ K+ +S EL E+ ENV +Q++S
Sbjct: 983 LKPEKEPVSLRCREL--EIIINHNRAENVQSCDTQVSS 1018
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 3202 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 3261
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 3262 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLESEKVRIREMSSTLDRE 3320
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 3321 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 3377
Query: 213 VKEVQ 217
++++
Sbjct: 3378 RQQME 3382
Score = 38.7 bits (86), Expect = 0.048
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 1946 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 1997
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 1998 ETEKLMKEKL--EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 2055
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 2056 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 2114
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 2115 LANHLKEKTD 2124
Score = 37.9 bits (84), Expect = 0.084
Identities = 68/374 (18%), Positives = 151/374 (40%), Gaps = 24/374 (6%)
Query: 50 ERELRQRIEREKADLSV----QVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
E+E ++++E+ +A+L Q++Q+ + L + + K + E + +
Sbjct: 423 EQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEME--NALRSYSN 480
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE---KEKSKFQAEVYELLAQVEN 162
+ + +E+ L+ E+ I Q+ Q K K +EK Q ++ +L+ ++ +
Sbjct: 481 ITV-NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEEL-S 538
Query: 163 VTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKV 221
++E+I ++ T E ++E H + + +I S + + ++ EV + K+
Sbjct: 539 FSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKI 598
Query: 222 NIENVVYLKSQIASQXXXX--XXXXXXXXXXXXXXXASLHQVEIDLE-SVRVQLEE-ESE 277
+E + K+ + + L +++ DLE R+ +E+ +
Sbjct: 599 KLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDN 658
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
+ ++Q+ E+ K + +K
Sbjct: 659 LGIHYKQQIDGLQNEMS---QKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSE 715
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLYE 393
+ Q + LQ E+E+L + EK GT +ELQ +TE LE+ E ++ L+E E
Sbjct: 716 EMTLQINELQKEIEILRQE-EKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLE 774
Query: 394 QTQRDLRNKQTELQ 407
L++++ L+
Sbjct: 775 AENSILKDEKKTLE 788
Score = 36.7 bits (81), Expect = 0.19
Identities = 57/270 (21%), Positives = 109/270 (40%), Gaps = 11/270 (4%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ +++ L ++L+ E E+ ++ E+EK L +V +L + E E + + +
Sbjct: 708 SLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQ 767
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
++ +L +L+D E+ + +QE + F + I +K EKE
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSV-WEKEIEILI 826
Query: 151 AEVYELLAQV----ENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI--TSHKQR 204
E +L Q E + K++ T S + E+ EL + L + D+ + +KQ
Sbjct: 827 EENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQE 886
Query: 205 LS-QENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L + ++ + E L+ V +KS + + L +
Sbjct: 887 LEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELME--- 943
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEI 293
LE + + E S+ DL QL GEI
Sbjct: 944 KLEVTKREKLELSQRLSDLSEQLKPKPGEI 973
Score = 34.7 bits (76), Expect = 0.79
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 3131 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 3190
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E KK
Sbjct: 3191 EAFRLEVKDKTDEVHLLNDTLASEQKK 3217
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 2597 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 2653
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 2654 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 2711
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 2712 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 2761
Score = 33.5 bits (73), Expect = 1.8
Identities = 57/342 (16%), Positives = 127/342 (37%), Gaps = 16/342 (4%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 1841 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 1900
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 1901 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRL 1960
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 1961 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAE- 2014
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 2015 KVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 2074
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 2075 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 2134
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
Q QRD++ + E++++ + + + A +K+ D H
Sbjct: 2135 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKH 2176
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 2183 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 2241
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 2242 TTRLQELEQE 2251
Score = 31.9 bits (69), Expect = 5.5
Identities = 55/316 (17%), Positives = 120/316 (37%), Gaps = 10/316 (3%)
Query: 118 KKKNQEIV-IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCE 175
+K +QE++ + Q++ Q+ + + K + E+ E L+ + V E K +++T
Sbjct: 3116 EKPSQELLEYNIQQKQSQMLEMQVELSSMKDR-ATELQEQLSSEKMVVAELKSELAQTKL 3174
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
LE T+ H ++EL +++ + N L E + + + K+++
Sbjct: 3175 ELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR 3234
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q+ + LE + QL ES+ +++ +R L A
Sbjct: 3235 SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK-QLLNESQQKIESQRMLYDAQLSEEQ 3293
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE--VEVL 353
R+ + + + + + L SE ++ L
Sbjct: 3294 GRN----LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 3349
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 3350 QKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHEL 3409
Query: 414 DKTREQKDALARENKK 429
E E ++
Sbjct: 3410 QSKVEDLQRQLEEKRQ 3425
>AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350
protein.
Length = 1773
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 35 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 91
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 92 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 151
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 152 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 211
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 212 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 268
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 269 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 325
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 326 ENQTYFKSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 381
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 382 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 441
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 442 ED-ELGSDI 449
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 1049 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 1108
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 1109 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLESEKVRIREMSSTLDRE 1167
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 1168 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 1224
Query: 213 VKEVQ 217
++++
Sbjct: 1225 RQQME 1229
Score = 34.7 bits (76), Expect = 0.79
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 978 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 1037
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E KK
Sbjct: 1038 EAFRLEVKDKTDEVHLLNDTLASEQKK 1064
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 444 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 500
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 501 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 558
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 559 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 608
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 30 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 88
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 89 TTRLQELEQE 98
Score = 31.9 bits (69), Expect = 5.5
Identities = 55/316 (17%), Positives = 120/316 (37%), Gaps = 10/316 (3%)
Query: 118 KKKNQEIV-IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCE 175
+K +QE++ + Q++ Q+ + + K + E+ E L+ + V E K +++T
Sbjct: 963 EKPSQELLEYNIQQKQSQMLEMQVELSSMKDR-ATELQEQLSSEKMVVAELKSELAQTKL 1021
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
LE T+ H ++EL +++ + N L E + + + K+++
Sbjct: 1022 ELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR 1081
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q+ + LE + QL ES+ +++ +R L A
Sbjct: 1082 SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK-QLLNESQQKIESQRMLYDAQLSEEQ 1140
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE--VEVL 353
R+ + + + + + L SE ++ L
Sbjct: 1141 GRN----LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 1196
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 1197 QKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHEL 1256
Query: 414 DKTREQKDALARENKK 429
E E ++
Sbjct: 1257 QSKVEDLQRQLEEKRQ 1272
>AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.
Length = 1978
Score = 50.4 bits (115), Expect = 1e-05
Identities = 63/265 (23%), Positives = 108/265 (40%), Gaps = 16/265 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE-G 80
+ IE + +LEDKI+ I L S R + RE+ L+V+ Q+ E E +
Sbjct: 297 LQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLE 356
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESE-ETAHLLKKKNQEIV-IDFQEQIDQLT-- 136
++ Q ++ DT K R L + +E L EI+ + Q + L
Sbjct: 357 CSKLQPSAVKQSDTMTEKERILAQSGSVEEVFRLRQALSDAENEIMRLSSLNQDNSLAED 416
Query: 137 --KTKAR---AEKEKSKFQAEVYELLAQVENVTKEKITISKTCER---LEITISELHIKI 188
K K R EKEKS E EL + + E I T R L+ + +L + +
Sbjct: 417 NLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNL 476
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
E + + S K+ L E EL ++ Q+ ++++ +K+Q++ Q
Sbjct: 477 EAKEQELNQSISEKETLIAEIEELDRQNQEA---TKHMILIKAQLSKQQNEGDSIISKLK 533
Query: 249 XXXXXXXASLHQVEIDLESVRVQLE 273
+HQ+E D + +L+
Sbjct: 534 QDLNDEKKRVHQLEDDKMDITKELD 558
Score = 42.3 bits (95), Expect = 0.004
Identities = 38/198 (19%), Positives = 91/198 (45%), Gaps = 16/198 (8%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK 98
K+++ + LE E+ L + +EK +L + +++L+ E + A ++ + L
Sbjct: 419 KLKMRIEVLEKEKSL---LSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLN 475
Query: 99 LRKLLEDVHLESEETAHL------LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L ++++ E L L ++NQE QL+K + + SK + +
Sbjct: 476 LEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKAQLSKQQNEGDSIISKLKQD 535
Query: 153 VYELLAQVENVTKEKITISKTCE-------RLEITISELHIKIEELNRTIVDITSHKQRL 205
+ + +V + +K+ I+K + + E+ +++LH+ ++L + ++ +
Sbjct: 536 LNDEKKRVHQLEDDKMDITKELDVQFVLLIQSEVALNDLHLTKQKLEDKVENLVDQLNKS 595
Query: 206 SQENIELVKEVQDLKVNI 223
+ N+ + KE +LK +I
Sbjct: 596 QESNVSIQKENLELKEHI 613
Score = 40.7 bits (91), Expect = 0.012
Identities = 31/192 (16%), Positives = 96/192 (50%), Gaps = 13/192 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQ--VIQLSERLEEAEGGAESQFEINR 90
++RL +++ ++ ++ R + Q + + D S Q + +L ++E + + + ++
Sbjct: 174 INRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQ 233
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+L++ H ++ + ++++E + D++E+I++L + +
Sbjct: 234 HE-------MSVLQNAH---QQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETD 283
Query: 151 -AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
+++YE+ ++ + EK+ +K E+LE I +++ K+ + +++L+ E
Sbjct: 284 LSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEK 343
Query: 210 IELVKEVQDLKV 221
++++E ++LK+
Sbjct: 344 RQIMEECENLKL 355
Score = 40.3 bits (90), Expect = 0.016
Identities = 45/209 (21%), Positives = 95/209 (45%), Gaps = 20/209 (9%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERL--------EEAEGGAESQF 86
+LEDK+ + D L +E I++E +L + Q E L + + S F
Sbjct: 580 KLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNF 639
Query: 87 E--INRKRDTELLKLRKLLEDVHLESE---ETAHLLKKKNQEIVI---DFQEQIDQLTKT 138
+ + ++R+ E+ L++ L ++ +E + A +K +N+++V+ D + Q+++
Sbjct: 640 KDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAG 699
Query: 139 KARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTIVD 197
+ EK+ + ++E + K + + + E TI EL LN + +
Sbjct: 700 NNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELS-NARNLNTSALQ 758
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + L + N + E+ +LK NIE +
Sbjct: 759 L--EHEHLIKLNQKKDMEIAELKKNIEQM 785
Score = 39.9 bits (89), Expect = 0.021
Identities = 77/419 (18%), Positives = 178/419 (42%), Gaps = 47/419 (11%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLSVQVIQ-LSERLEEAEGGAESQFEINR------- 90
++ I++ LE E + Q+I ++ +Q++Q L E+ +E + ++N
Sbjct: 900 QLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFL 959
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK-EKSKF 149
++D E+ L+K +E + + E ++ N +I FQE Q + +EK + SK
Sbjct: 960 EKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDI---FQETKVQSLNIENGSEKHDLSKA 1016
Query: 150 QAE-----VYELLAQVENVTKEKITISKTCERL------EIT--ISELHIKIEELNRTIV 196
+ E + E +++ + ++ I+++K ++L ++T I + ++I+ L+ I
Sbjct: 1017 ETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARIS 1076
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
TSH +Q+ + L +++Q + E V + ++ + A
Sbjct: 1077 S-TSH----TQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEA 1131
Query: 257 SLHQVEIDLESVRVQLEEES-----EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXX 311
+L +++ + + + + E E +L R + + + EI K
Sbjct: 1132 ALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSS 1191
Query: 312 XXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRT 371
+ L+ + + +++Q +++ + ++ ++ + +LQ+
Sbjct: 1192 TG-----NEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEEL 1246
Query: 372 EQLER---VNIEIKSRLEET----VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
QL+ V+ + S+L+ +Q YEQ + L+N EL +V H + + KD L
Sbjct: 1247 HQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLL 1305
Score = 37.9 bits (84), Expect = 0.084
Identities = 47/216 (21%), Positives = 103/216 (47%), Gaps = 23/216 (10%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQR---IEREKA-----DLSVQVIQLSERLEEAEGGAE 83
+L ++++ +Q++LE RE + R + K +L+ +V QL+ E E +
Sbjct: 854 SLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIK 913
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ---EIVIDFQEQIDQLTKT-- 138
+I ++ ++L + L++ E +E + ++ N ++ ++ E+I L KT
Sbjct: 914 HHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIE 973
Query: 139 --KARAEKEKSKFQAEVYELLAQVE----NVTK--EKITISKT-CERLEITISELHIKIE 189
K + +E+ Q + ++ + + N+ EK +SK ERL I E ++I+
Sbjct: 974 QIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIK 1033
Query: 190 ELNRTIVDITSHKQRLSQENI-ELVKEVQDLKVNIE 224
LN + +T +LS++ + +L + +Q + I+
Sbjct: 1034 LLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQ 1069
Score = 37.5 bits (83), Expect = 0.11
Identities = 32/201 (15%), Positives = 83/201 (41%), Gaps = 6/201 (2%)
Query: 83 ESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARA 142
E ++N+K+D E+ +L+K +E + + +ET +L +E Q+Q+ QL K
Sbjct: 762 EHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEE-----QKQLTQLINKKEIF 816
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
++ + +++ E L + ++ + +T E + ++ + + L + + +
Sbjct: 817 IEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQ 876
Query: 203 QRLSQ-ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
R + + + + V +L + + +K + + SL +
Sbjct: 877 SRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQ 936
Query: 262 EIDLESVRVQLEEESEARLDL 282
+ +++ R Q E+ + L
Sbjct: 937 KKEMDEFRYQHEQMNATHTQL 957
Score = 31.1 bits (67), Expect = 9.7
Identities = 27/125 (21%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 46 DLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLED 105
+LE +++L ++ +L +VI L E L+EA +S + + D + ++ +L
Sbjct: 1693 ELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQ 1752
Query: 106 VHLESEETAHLLKKKNQEIVIDFQEQIDQ-LTKTKARAEKEKSKFQA-EVYELLAQVENV 163
L +E ++KK + + ++D+ L + K Q EV L+ + V
Sbjct: 1753 NELR-QEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGV 1811
Query: 164 TKEKI 168
+E++
Sbjct: 1812 RREEM 1816
>AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.
Length = 2058
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/429 (18%), Positives = 180/429 (41%), Gaps = 30/429 (6%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
+ ++ A+ A+ R E +I +++ LE + R+ +E + ++ +QL + +E+
Sbjct: 397 LEVQLQAERDAIDRKEKEITNLEEQLE---QFREELENKNEEVQQLHMQLEIQKKESTTR 453
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
+ + N+ ++ KL +++ S + H+L K +I+ + + +IDQL + +
Sbjct: 454 LQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTK 513
Query: 142 AEKE-----KSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEELNRTI 195
+++ +K E EL+ +E + ++ + +R E I +L+ IE+L + +
Sbjct: 514 LQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQEL 573
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
+I Q+ S L +E LK ++ V+ K + Q
Sbjct: 574 ANI---GQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETN 630
Query: 256 ASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXX 315
++Q+ +L S++ + E + + E + N I H
Sbjct: 631 FKMNQLTQELFSLKRERESVEKIQSIPENSV---NVAIDHLSKDKPELEVVLTEDALKSL 687
Query: 316 XKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR----T 371
+ ++I N+E + +L+S V ++L + +++Q++ T
Sbjct: 688 ENQTYFKSFEENGKGSII----NLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 743
Query: 372 EQLERVNIEIKSRLEETV--QLYEQTQRDLRNKQTEL----QRVSHELDKTREQKDALAR 425
E L++ + ++ +EE V L Q Q + + + Q +S E ++T Q R
Sbjct: 744 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 803
Query: 426 ENKKMGDDL 434
E+ ++G D+
Sbjct: 804 ED-ELGSDI 811
Score = 43.6 bits (98), Expect = 0.002
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 38 DKIRLIQDDLESE----RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRD 93
D++ L+ D L SE REL+ +E+EKA L + E LE+ + ESQ + N + +
Sbjct: 1411 DEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLN 1470
Query: 94 TELLKLRKLLEDVHLESEETAHLLKKK-NQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
L + ++LL + + E L + ++E + + Q+ L K R + S E
Sbjct: 1471 LLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQV-LLESEKVRIREMSSTLDRE 1529
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
EL AQ++ + + S+ E + EL ++EE + IV++ + ++ ++++
Sbjct: 1530 -RELHAQLQ--SSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQT 1586
Query: 213 VKEVQ 217
++++
Sbjct: 1587 RQQME 1591
Score = 38.7 bits (86), Expect = 0.048
Identities = 44/190 (23%), Positives = 88/190 (46%), Gaps = 15/190 (7%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ RLE ++ + L+ +Q+I+ E+ LS Q E ++ G E Q +
Sbjct: 155 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQ----KEAMKAEAGPVEQQL----LQ 206
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+TE L KL +V ++E+ L+K+ + + ID +EQ+ + + + E + +
Sbjct: 207 ETEKLMKEKL--EVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQ 264
Query: 153 VYELLAQVENVTK--EKITISKTCER--LEITISELHIKIEELNRTIVDITSHKQRLSQE 208
L Q+E + K ++ I + ER + I +L +++ + R I+ H+ R ++
Sbjct: 265 NQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPR-FQPISEHQTREVEQ 323
Query: 209 NIELVKEVQD 218
+KE D
Sbjct: 324 LANHLKEKTD 333
Score = 34.7 bits (76), Expect = 0.79
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
QS++ + ++L A ELQ++ + V E+KS L +T E T + EL
Sbjct: 1340 QSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKEL 1399
Query: 407 QRVSHEL-DKTRE---QKDALARENKK 429
+ E+ DKT E D LA E KK
Sbjct: 1400 EAFRLEVKDKTDEVHLLNDTLASEQKK 1426
Score = 33.9 bits (74), Expect = 1.4
Identities = 33/170 (19%), Positives = 81/170 (47%), Gaps = 9/170 (5%)
Query: 25 EYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
E +D+SAL S LE ++ + L E+E + E+ + ++++L + LE G
Sbjct: 806 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLE---G 862
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
+ Q E +KR + +++ K ++ +EE+ + + + + +L K
Sbjct: 863 NEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFF--NELEALRAESVATKAELASYKE 920
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEE 190
+AEK + + + + + +++++ + +++ E+L I E +++E
Sbjct: 921 KAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQE 970
Score = 33.5 bits (73), Expect = 1.8
Identities = 57/342 (16%), Positives = 127/342 (37%), Gaps = 16/342 (4%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
E++ L +K E + + Q++ T+ +E + + E E L E +
Sbjct: 50 EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEEL 109
Query: 164 TKEKITISKTCERLEITISELHIKIEE-------LNRTIVDITSHKQRLSQENIELVKEV 216
+ S+ E+L + +S+ I+ R I + T RL QE + +
Sbjct: 110 RERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRL 169
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
Q+L+ + + + ++ Q L + E + VQ + E
Sbjct: 170 QELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMK-----EKLEVQCQAE- 223
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
+ R DL++Q+ ++ S+F + L +
Sbjct: 224 KVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQA 283
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLY---E 393
+ E ++ Q E++ L L+ + +T ++E++ +K + ++ +L E
Sbjct: 284 IDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKE 343
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLH 435
Q QRD++ + E++++ + + + A +K+ D H
Sbjct: 344 QLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKH 385
Score = 32.7 bits (71), Expect = 3.2
Identities = 20/70 (28%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 343 KSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNK 402
K L EV+ L + + + +E+ EQLE+ E++++ EE QL+ Q + +
Sbjct: 392 KPELSLEVQ-LQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKES 450
Query: 403 QTELQRVSHE 412
T LQ + E
Sbjct: 451 TTRLQELEQE 460
Score = 31.9 bits (69), Expect = 5.5
Identities = 55/316 (17%), Positives = 120/316 (37%), Gaps = 10/316 (3%)
Query: 118 KKKNQEIV-IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE-KITISKTCE 175
+K +QE++ + Q++ Q+ + + K + E+ E L+ + V E K +++T
Sbjct: 1325 EKPSQELLEYNIQQKQSQMLEMQVELSSMKDR-ATELQEQLSSEKMVVAELKSELAQTKL 1383
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
LE T+ H ++EL +++ + N L E + + + K+++
Sbjct: 1384 ELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGR 1443
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q+ + LE + QL ES+ +++ +R L A
Sbjct: 1444 SEERDKEELEDLKFSLESQKQRNLQLNLLLEQQK-QLLNESQQKIESQRMLYDAQLSEEQ 1502
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE--VEVL 353
R+ + + + + + L SE ++ L
Sbjct: 1503 GRN----LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKEL 1558
Query: 354 IIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE+ + EL TE+ + +++ + ++E+ Q++ +T + + TE Q+ HEL
Sbjct: 1559 QKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHEL 1618
Query: 414 DKTREQKDALARENKK 429
E E ++
Sbjct: 1619 QSKVEDLQRQLEEKRQ 1634
>AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein
protein.
Length = 1258
Score = 50.4 bits (115), Expect = 1e-05
Identities = 51/221 (23%), Positives = 109/221 (49%), Gaps = 17/221 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE------ 83
L +S LE+++ ++ + RE I+R+ A S + SE LE E G +
Sbjct: 210 LERVSALEEELAAANQEIVALREQNVHIQRKMA--SSEGSTESEHLEGMEPGQKVHEKRL 267
Query: 84 SQFEINRKRDT-ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARA 142
S I+ +T ++++L++LLE + E + L + + + +++ + K +
Sbjct: 268 SNGSIDSTDETSQIVELQELLEKQNYEMAQMKERLAALSSRVG-EVEQEAETARKDLIKT 326
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISK---TCERLEITISELHIKIE-EL--NRTIV 196
E+ +K+Q ++ E +AQ E++ + T+ K + +R +I +++ K+E EL I+
Sbjct: 327 EEMNTKYQRDIREAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAIL 386
Query: 197 DITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQ 236
K R QE +EL ++ +Q E + +++++A +
Sbjct: 387 RQMEEKNRQLQERLELAEQKLQQTMRKAETLPEVEAELAQR 427
Score = 37.5 bits (83), Expect = 0.11
Identities = 76/416 (18%), Positives = 158/416 (37%), Gaps = 27/416 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIERE-KADLSVQVIQLSERLEEAEGGAESQF-- 86
L L ++ + L Q L+ R ++R+ + L + L+ L ++G +F
Sbjct: 57 LDTLRETQESLSLAQQRLQDVIYDRDSLQRQLNSALPQDIESLTGGLAGSKGADPPEFAA 116
Query: 87 ---EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
E+N R+ +LL+ + + ++ E T LL+ + E ++ E+ ++T K +A+
Sbjct: 117 LTKELNACRE-QLLEKEEEISELKAERNNTRLLLE--HLECLVSRHERSLRMTVVKRQAQ 173
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
S +EV L A K K ERL +++ + EEL +I +
Sbjct: 174 SP-SGVSSEVEVLKALKSLFEHHKALDEKVRERLRVSLERVSALEEELAAANQEIVA--- 229
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
L ++N+ + +++ + + E+ +L+ Q Q+ +
Sbjct: 230 -LREQNVHIQRKMASSEGSTESE-HLEGMEPGQKVHEKRLSNGSIDSTDETS----QI-V 282
Query: 264 DLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
+L+ + LE+++ ++ +L + +G + KY
Sbjct: 283 ELQEL---LEKQNYEMAQMKERLAALSSRVGEVEQE-AETARKDLIKTEEMNTKYQRDIR 338
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKS 383
+ +I +EK+ Q E + +K + Q+E N +++
Sbjct: 339 EAMAQKEDMEERITTLEKRYLSAQRESTSIHDMNDKLENELANKEAILRQMEEKNRQLQE 398
Query: 384 RLEETVQLYEQTQR---DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
RLE Q +QT R L + EL + L K E+ + + + L +
Sbjct: 399 RLELAEQKLQQTMRKAETLPEVEAELAQRIAALTKAEERHGNIEERMRHLEGQLEE 454
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/414 (19%), Positives = 174/414 (42%), Gaps = 35/414 (8%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE K +++D LE R ++ +L + +QL +L + E + +++RK+ E
Sbjct: 282 LETKT-MLEDQLEGTRARSDKLH----ELEKENLQLKAKLHDME----MERDMDRKKIEE 332
Query: 96 LLKLRKLLEDVHLES-EETAHL---LKK--KNQEIVIDFQE----QIDQLTKTKA-RAEK 144
L++ LE +S +E+ HL L++ + E+ Q+ ++++LT ++ + E
Sbjct: 333 LMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEM 392
Query: 145 EKSKFQAEVYELLAQVENV---TKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
E V EL V++V + + + K +RL + L +I + +++ + +
Sbjct: 393 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 452
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
+ L +E +L K ++ L+ N E + + Q A + +
Sbjct: 453 SKDLMKEKAQLEKTIETLRENSERQIKILEQ--ENEHLNQTVSSLRQRSQISAEARVKDI 510
Query: 262 EIDLESVRVQLEEESE--ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
E + + + ++E S ++++ E++ +K E+ H++ K K +
Sbjct: 511 EKENKILHESIKETSSKLSKIEFEKRQIKK--ELEHYKEK--GERAEELENELHHLEKEN 566
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA---RELQKRTEQLER 376
KI +E++ S L+ E L L+ L+K QL+
Sbjct: 567 ELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE 626
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
N+E++ R E+++ L+ + EL+ +L K E A ++ +++
Sbjct: 627 ENLELR-RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 679
Score = 44.8 bits (101), Expect = 7e-04
Identities = 44/206 (21%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
+L++ +++R D +E ++E+E LS +V L + + + ++ +++
Sbjct: 396 SLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD 455
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARA---EKEK 146
E +L K +E + SE +L+++N+ + + Q Q++ +AR EKE
Sbjct: 456 LMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS-AEARVKDIEKEN 514
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
+ E +++ + EK I K E + E + EEL + L
Sbjct: 515 KILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENEL-------HHLE 563
Query: 207 QENIELVKEVQDLKVNIENVVYLKSQ 232
+EN L K++ +LK+ E + L+ +
Sbjct: 564 KENELLQKKITNLKITCEKIEALEQE 589
Score = 44.4 bits (100), Expect = 0.001
Identities = 57/221 (25%), Positives = 102/221 (46%), Gaps = 30/221 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQR----------IEREKADLSVQVIQLSERLEEAEG 80
S LS++E + R I+ +LE +E +R +E+E L ++ L E+ E
Sbjct: 526 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 585
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ--EIVIDFQEQIDQLTKT 138
+ E+ R E KL+K L+ + + L K+ +Q E ++ + ++ L
Sbjct: 586 LEQENSELER----ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC- 640
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTK--EKITIS-KTCERLEITISELHIK-------I 188
A + ++ Q E EL ++ E + K E + S K ERLE++ L I+ +
Sbjct: 641 ---ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTL 697
Query: 189 EELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYL 229
E N+ I + S Q L EN L K +++LK++ + + L
Sbjct: 698 ENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 738
Score = 42.3 bits (95), Expect = 0.004
Identities = 68/367 (18%), Positives = 145/367 (39%), Gaps = 24/367 (6%)
Query: 55 QRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA 114
+R+ E+ + S +I+LSE + + + +K + + + +E +
Sbjct: 123 KRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAK 182
Query: 115 HLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKITIS 171
+++ QE+ +E+ +QL K E+ E + Q E LL+ + + +
Sbjct: 183 AKIRRLRQEL----EEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD 238
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKS 231
E+ + + +L ++ + DI +K R +E +KE D +V +E L+
Sbjct: 239 ALREKA-VRVDKLESEVSRYKERLHDIEFYKAR-----VEELKE--DNQVLLETKTMLED 290
Query: 232 QIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANG 291
Q+ A LH +E++ + R ++EE E + LE ++
Sbjct: 291 QLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD 349
Query: 292 EIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVE 351
E H + + S L+ +E + L VE
Sbjct: 350 ESLHLGWEL---EQISRTSELSEAPQKSLGHEVNELTSSRLL----KLEMENQSLTKTVE 402
Query: 352 VLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSH 411
L ++ G A ++ K ++ +R++ +++ E VQ +Q+ ++ +N +L +
Sbjct: 403 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQ-EKQSLQNCQNLSKDLMKEKA 461
Query: 412 ELDKTRE 418
+L+KT E
Sbjct: 462 QLEKTIE 468
Score = 39.1 bits (87), Expect = 0.037
Identities = 27/116 (23%), Positives = 57/116 (49%), Gaps = 9/116 (7%)
Query: 334 AKINNVEKQKSRLQSEVEVL---II----DLEKANGTARELQKRTEQLERVNIEIKSRLE 386
+KI +EK+ RL +VE+L I+ L+ +++L K QLE+ ++ E
Sbjct: 416 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 475
Query: 387 ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+++ EQ L + L++ S ++ KD + +ENK + + + + + ++
Sbjct: 476 RQIKILEQENEHLNQTVSSLRQRS-QISAEARVKD-IEKENKILHESIKETSSKLS 529
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 49.6 bits (113), Expect = 3e-05
Identities = 86/427 (20%), Positives = 169/427 (39%), Gaps = 34/427 (7%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E L L + ++R + +L+ + + Q + E+ + ++ ERL+E G E+
Sbjct: 474 ELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEA 533
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDF---QEQIDQLTKTKAR 141
+ + +EL+ LR+ LE HLE E LL+++ E+ ++ I +L+ ++
Sbjct: 534 K---QSESLSELITLREALESSHLEGE----LLRQEQTEVTAALARAEQSIAELSSSENT 586
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE----ITISELHIKIEELNRTIVD 197
+ E + +A +L A E + +K+ +++ +LE S + + N VD
Sbjct: 587 LKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVD 646
Query: 198 ITSHKQR---LSQENIELVKEVQ-------DLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
+ ++R L ++N L ++Q +L+ ++ ++ K +I +
Sbjct: 647 LAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK----LSESRHQ 702
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
LHQ E V + +E EA + + L + R
Sbjct: 703 QEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGL 762
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXT---LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA 364
T L +I V + K +Q EV L ++L+ A
Sbjct: 763 SSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQA 822
Query: 365 -RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+E QL + E K+ LE+ +E+ LR K E +R H+ + + ++L
Sbjct: 823 EQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK-WEKERSWHQ-QELAKALESL 880
Query: 424 ARENKKM 430
RE ++
Sbjct: 881 EREKMEL 887
Score = 47.6 bits (108), Expect = 1e-04
Identities = 81/378 (21%), Positives = 149/378 (39%), Gaps = 43/378 (11%)
Query: 73 ERLEEAEGGAESQ-----FEINRKRDTELLKLRKLLEDVHLESEETA-HLLKK---KNQE 123
E E GG +S E ++ L K LL + E+ +A H L + K Q+
Sbjct: 1198 ESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQ 1257
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE 183
++Q+ +L + E EKS+ E+ +L Q+ +EK LE + E
Sbjct: 1258 TRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
LH T+ + S +R + +E E + L+ EN L +Q+
Sbjct: 1318 LH-------ETMASLQSRLRRAELQRMEAQGERELLQAAKEN---LTAQVEHLQAAVVEA 1367
Query: 244 XXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXX 303
+E DL + R L+ ++E ++ ER+ +A E G +
Sbjct: 1368 RAQASAAGI--------LEEDLRTARSALKLKNE-EVESERERAQALQEQGELK------ 1412
Query: 304 XXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT 363
+ TL +I +EKQ+ ++ +E+L +DL+K N
Sbjct: 1413 -VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQE 1471
Query: 364 A-------RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKT 416
+EL+K LE + + ++ R ++ EQ + ++++T+ + H+L +
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLEL 1531
Query: 417 REQKDALARENKKMGDDL 434
E+KD + + DL
Sbjct: 1532 -EKKDQMIESQRGQVQDL 1548
Score = 45.6 bits (103), Expect = 4e-04
Identities = 65/272 (23%), Positives = 118/272 (43%), Gaps = 15/272 (5%)
Query: 25 EYSADLSALSR--LEDKIRLIQDDLESERELRQRIE-REKADLSVQVIQLS---ERLEEA 78
E + L +L R +E ++RL + E E QR E R +A+ ++ +QL ER+
Sbjct: 872 ELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL 931
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
E ++Q E+ +L +LR+ ++ L+ +ET +L+ + QE + +E Q
Sbjct: 932 ETLLQTQKEL-ADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD 990
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
A ++E S + +L QVE++ + + + +E + E + +E NR ++
Sbjct: 991 LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKEL 1050
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
K L+ + L+++ Q L V ++ ++ Q S L
Sbjct: 1051 EREKASLT---LSLMEKEQRLLV-LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELL 1106
Query: 259 HQ----VEIDLESVRVQLEEESEARLDLERQL 286
Q E D + QL EE EA E+QL
Sbjct: 1107 RQEVKEKEADFLAQEAQLLEELEASHITEQQL 1138
Score = 45.2 bits (102), Expect = 6e-04
Identities = 64/412 (15%), Positives = 154/412 (37%), Gaps = 16/412 (3%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+ L + ++ ++ + +S R + L + + L+ E Q E++R
Sbjct: 1933 AVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSR 1992
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKS 147
+ L+ L+ S + L+ + EI + +QE + QL + A+ ++E
Sbjct: 1993 SLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEEL- 2051
Query: 148 KFQAEVYELLAQV------ENVTKEKITISKTCERLEI-----TISELHIKIEELNRTIV 196
+ Q E +LL + EN+ +EK + + E EI ++ EL + + + + I+
Sbjct: 2052 RHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEIL 2111
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++ +QR + E + + ++ + L+ ++ +
Sbjct: 2112 ELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWRE 2171
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ + L + + E + L+ +++ + E + +
Sbjct: 2172 KAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPG 2231
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
S + +++ VE + S E + LE L+ +L+R
Sbjct: 2232 ATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQR 2291
Query: 377 VNIEIKSRLEETVQLYEQTQRD-LRNKQTELQRVSHELDKTREQKDALAREN 427
N++++S LE+ + + +R+ +R Q +S + Q+D ++N
Sbjct: 2292 HNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKN 2343
Score = 41.1 bits (92), Expect = 0.009
Identities = 61/298 (20%), Positives = 112/298 (37%), Gaps = 17/298 (5%)
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LL K QE+ + E+ +L + K++ + EK++ Q V EL A + K+ K +
Sbjct: 248 LLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIK 307
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
L T ++I E N T ++ H+ LS+ E +Q + +I V+ + +
Sbjct: 308 ALRET-----VEILETNHT--ELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIA 360
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q + L VR L +A DL +QL +
Sbjct: 361 QGSGHENSLELDSSIFSQF--DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLII 355
+ + K + L +++++ K++ LQ E L
Sbjct: 419 LQQQ-HDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE L++ +L RVN+E++ + + E+ Q +L E +R+ L
Sbjct: 478 QLE-------VLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML 528
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/406 (17%), Positives = 167/406 (41%), Gaps = 23/406 (5%)
Query: 33 LSRLEDKIRLIQ-DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
++ L+ ++R + +E++ E R+ ++ K +L+ QV L + EA A + +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGE-RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEED 1380
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID--FQEQIDQLTKTKARAEKEKSKF 149
T L+ E+V E E L ++ ++ QE + LT+T A E+E
Sbjct: 1381 LRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETL 1440
Query: 150 QAEVYELLAQ--VENVTKEKITISKTCERLEITISELHIKIEELNRTIVD-----ITSHK 202
+ ++ EL Q ++ E +++ E+ + + I+ E R++++ + +
Sbjct: 1441 RGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQERE 1500
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L+ + E ++E++ + NV L+ Q+ L +
Sbjct: 1501 QKLTVQR-EQIRELEKDRETQRNV--LEHQLLE-----LEKKDQMIESQRGQVQDLKKQL 1552
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
+ LE + ++L EE+ +++ +++L+K E + +
Sbjct: 1553 VTLECLALEL-EENHHKMECQQKLIK-ELEGQRETQRVALTHLTLDLEERSQELQAQSSQ 1610
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
T++A+ Q+ + Q E ++ + +K + T ++L++R ++L I+
Sbjct: 1611 IHDLESHSTVLARELQERDQEVKSQRE-QIEELQRQKEHLT-QDLERRDQELMLQKERIQ 1668
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
++ + + + DL + L+ EL R+ A E K
Sbjct: 1669 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714
Score = 40.3 bits (90), Expect = 0.016
Identities = 73/449 (16%), Positives = 177/449 (39%), Gaps = 32/449 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
+ES+R Q ++++ L ++L E + E + E+ +R+T+ + L L D+
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
S+E L+ ++ +I ++ + AR +E+ + EV Q+E + ++
Sbjct: 1598 EERSQE----LQAQSSQI-----HDLESHSTVLARELQERDQ---EVKSQREQIEELQRQ 1645
Query: 167 KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
K +++ ER + EL ++ E + + + D + + ++ +E++E +K L+ +
Sbjct: 1646 KEHLTQDLERRD---QELMLQKERI-QVLEDQRTRQTKILEEDLEQIK--LSLRERGREL 1699
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
+ + + L E ++E + + E E + LE+QL
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQL 1759
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRL 346
+ ++G + + +L ++++ ++ ++
Sbjct: 1760 QGLHRKVG----ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+E L + ++A G ++++ + L+ LE+ ++ +L++ + +
Sbjct: 1816 DQELEALQQEQQQAQGQEERVKEKADALQ-------GALEQAHMTLKERHGELQDHKEQA 1868
Query: 407 QRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXT 466
+R+ EL + AL + +GD ++R
Sbjct: 1869 RRLEEELAVEGRRVQAL---EEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 467 AAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
++ +A+A K +Q + L AE RH
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRH 1954
Score = 38.3 bits (85), Expect = 0.064
Identities = 79/419 (18%), Positives = 164/419 (39%), Gaps = 45/419 (10%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
T+V + +++ L ++ ++ R ++ L++ + L+++L + E
Sbjct: 564 TEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLE 623
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E+Q +R E + R L+ E+E+ L +KN + Q
Sbjct: 624 --EENQSVCSRMEAAE--QARNALQVDLAEAEKRREALWEKNTHLEAQLQ---------- 669
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
+AE+ ++ QA++ ++ + E + K+ +S++ + E ++L E+L++
Sbjct: 670 -KAEEAGAELQADLRDIQEEKEEIQKK---LSESRHQQEAATTQL----EQLHQEAKRQE 721
Query: 200 SHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
R QE LV+E L+V ++ V + +A Q
Sbjct: 722 EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+E+ + VQ++ ++A+ ++ ++ E+ RS+ +
Sbjct: 782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGK 841
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKRTEQLERVN 378
+E+QK+ + EV L EK +EL K E LER
Sbjct: 842 TA-----------------LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK 884
Query: 379 IEIKSRLEETVQLYE--QTQRDLRNKQTELQRVSHELDKTREQ---KDALARENKKMGD 432
+E++ RL+E E Q QR+ Q E +L+ +E+ + L + K++ D
Sbjct: 885 MELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELAD 943
Score = 37.1 bits (82), Expect = 0.15
Identities = 64/402 (15%), Positives = 158/402 (39%), Gaps = 18/402 (4%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ ++ E++R + + + S ++ S ++ + E + ++RD E+
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ 1635
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV-YELLA 158
R+ +E++ + E L++++QE+++ +E+I L + R K + ++ L
Sbjct: 1636 REQIEELQRQKEHLTQDLERRDQELMLQ-KERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1694
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ +T ++ + + E + +E + + D K++ + E + E+Q+
Sbjct: 1695 RGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRD----KEKEVECQQEHIHELQE 1750
Query: 219 LKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESE 277
LK +E + L ++ + Q E+ +S++ QL+E
Sbjct: 1751 LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1810
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
A +++L E + + + ++
Sbjct: 1811 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERH--------GELQ 1862
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+ ++Q RL+ E+ V ++ +L+ + + E+ + ++ + E Q +E R
Sbjct: 1863 DHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETR 1922
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
L++ + Q V E D ++ +AL E++ ARA
Sbjct: 1923 ALQDSWLQAQAVLKERD---QELEALRAESQSSRHQEEAARA 1961
>X97053-1|CAA65765.1| 566|Homo sapiens plectin protein.
Length = 566
Score = 49.2 bits (112), Expect = 3e-05
Identities = 75/416 (18%), Positives = 157/416 (37%), Gaps = 32/416 (7%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSE----RLEEAEGGAESQFEINRKRDTEL 96
RL +D+ R L ++ + KAD+ ++ QL + LE +G E R+ + E+
Sbjct: 112 RLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEI 171
Query: 97 LKLRKLLEDVHLESEETAHLLKK--KNQEIVIDFQEQ--IDQLTKTKARAEKEKSKFQAE 152
L L+ E E L + N E + +EQ ++ + + AE+E+ + +AE
Sbjct: 172 LALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE 231
Query: 153 --VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSH--KQRL 205
V + LA E +++ + ERL+ + E L + E+ + + + ++RL
Sbjct: 232 ERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRL 291
Query: 206 SQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH------ 259
E VQ + ++ + + + Q
Sbjct: 292 QAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQA 351
Query: 260 --QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHW---RSKFXXXXXXXXXXXXXX 314
QVE + E ++ EE+++AR + K E R++
Sbjct: 352 RRQVE-EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 410
Query: 315 XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQL 374
K+ + ++ + Q + +L +L++ A E ++ Q+
Sbjct: 411 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 470
Query: 375 ERVNIEIKSRLEETVQLYEQTQRD-----LRNKQTELQRVSHELDKTREQKDALAR 425
E ++ ++EE +L + + + LR+K + + E +K ++ + AR
Sbjct: 471 EEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAAR 526
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/415 (17%), Positives = 158/415 (38%), Gaps = 34/415 (8%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A + +RL+ + + + E+E E R+ R D + Q +L E+ + + E
Sbjct: 81 EKLAAIGEATRLKTEAEIALKEKEAENE---RLRRLAEDEAFQRRRLEEQAAQHKADIEE 137
Query: 85 QF-EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
+ ++ + D+EL + + L+ED L+++ Q +E+I L + +A
Sbjct: 138 RLAQLRKASDSELERQKGLVEDT----------LRQRRQ-----VEEEILALKASFEKAA 182
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K++ + E+ + + E+ + K R +E + E + + ++
Sbjct: 183 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEE 242
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEI 263
+++ ++EV+ LK N+E L+ + + H +
Sbjct: 243 EAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 302
Query: 264 DLESVRVQLEEESEARLDLERQLV-KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
Q E+E + L E+ ++ + GE ++ + +
Sbjct: 303 Q------QKEQELQQTLQQEQSVLDQLRGE-----AEAARRAAEEAEEARVQAEREAAQA 351
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
L K + E+ ++R Q++ + E AR Q L R
Sbjct: 352 RRQVEEAERL--KQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAAL-RQKQAAD 408
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDA 437
+ +E+ + EQT R + EL + +L++T QK+ L E +++ + +A
Sbjct: 409 AEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA 463
Score = 37.9 bits (84), Expect = 0.084
Identities = 49/254 (19%), Positives = 109/254 (42%), Gaps = 18/254 (7%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT--- 94
+++ ++ ++E R LR+R E+E A + +++ +AE A + F + +K
Sbjct: 253 EEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHA-FAVQQKEQELQQ 311
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
L + + +L+ + E+E A ++ +E + + + Q + AE+ K + +
Sbjct: 312 TLQQEQSVLDQLRGEAE-AARRAAEEAEEARVQAEREAAQARRQVEEAERLKQSAEEQA- 369
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIE 211
+ AQ + EK+ E +E + + ++ HK+ Q + +
Sbjct: 370 QARAQAQ-AAAEKLRKEAEQEAARRAQAE-QAALRQKQAADAEMEKHKKFAEQTLRQKAQ 427
Query: 212 LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
+ +E+ L++ +E + K+ + + QVE +L SVRVQ
Sbjct: 428 VEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRS-------QVEEELFSVRVQ 480
Query: 272 LEEESEARLDLERQ 285
+EE S+ + +E +
Sbjct: 481 MEELSKLKARIEAE 494
>U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1b
protein.
Length = 1202
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/293 (18%), Positives = 120/293 (40%), Gaps = 13/293 (4%)
Query: 11 TYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQ 70
T +SG ++D ++ + DL+ + L++ +I + ++++R+ A LS V +
Sbjct: 230 TPSTSGKRSSDGSLSHEEDLAKVIELQE---IISKQSREQSQMKERL----ASLSSHVTE 282
Query: 71 LSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV--HLESEETAHLLKKKNQEIVIDF 128
L E L+ A E+N K ++ + ED+ + + E +L ++ V D
Sbjct: 283 LEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDL 342
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE---LH 185
++++ K ++ ++ E L E ++ + ++T +E +++
Sbjct: 343 NDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402
Query: 186 IKIEELNRTIVD-ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
K EE + I + + + +L ++N EL + Q K+N E+ L +
Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERL 462
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWR 297
+ + ++ES + QLEE + L + E+ H R
Sbjct: 463 QLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMR 515
Score = 37.9 bits (84), Expect = 0.084
Identities = 81/416 (19%), Positives = 157/416 (37%), Gaps = 23/416 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA--EGGAESQFEINR 90
+S LE++ RL+ D L +E + + ++ + L +L A + A E+N
Sbjct: 41 VSMLEERDRLL-DTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNV 99
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
R+ +LL+ + + ++ E T LL+ + E ++ E+ ++T K +A+
Sbjct: 100 CRE-QLLEREEEIAELKAERNNTRLLLE--HLECLVSRHERSLRMTVVKRQAQSPAG-VS 155
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+EV L A K K ERL + + + EEL T ++ K++ +Q+
Sbjct: 156 SEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKK- 214
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
L V D+ EN + +S + + + ++
Sbjct: 215 TLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLA 274
Query: 271 QLEE---ESEARLDLERQ-LVKA---NGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
L E E LD R+ L+K+ N ++ + +Y
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRY-LAAQ 333
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVE----VLIIDLEKANGTARELQKRTEQLERVNI 379
L K+ N K + + E L LE A ++ ++ E L V
Sbjct: 334 REATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEA 393
Query: 380 EIKSR---LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
E+ R L + + + + LR + +L+ + EL + R+++ NK++ D
Sbjct: 394 ELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSD 449
>U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1a
protein.
Length = 1185
Score = 49.2 bits (112), Expect = 3e-05
Identities = 55/293 (18%), Positives = 120/293 (40%), Gaps = 13/293 (4%)
Query: 11 TYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQ 70
T +SG ++D ++ + DL+ + L++ +I + ++++R+ A LS V +
Sbjct: 230 TPSTSGKRSSDGSLSHEEDLAKVIELQE---IISKQSREQSQMKERL----ASLSSHVTE 282
Query: 71 LSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV--HLESEETAHLLKKKNQEIVIDF 128
L E L+ A E+N K ++ + ED+ + + E +L ++ V D
Sbjct: 283 LEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDL 342
Query: 129 QEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE---LH 185
++++ K ++ ++ E L E ++ + ++T +E +++
Sbjct: 343 NDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAAL 402
Query: 186 IKIEELNRTIVD-ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXX 244
K EE + I + + + +L ++N EL + Q K+N E+ L +
Sbjct: 403 SKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERL 462
Query: 245 XXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWR 297
+ + ++ES + QLEE + L + E+ H R
Sbjct: 463 QLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMR 515
Score = 37.9 bits (84), Expect = 0.084
Identities = 81/416 (19%), Positives = 157/416 (37%), Gaps = 23/416 (5%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA--EGGAESQFEINR 90
+S LE++ RL+ D L +E + + ++ + L +L A + A E+N
Sbjct: 41 VSMLEERDRLL-DTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNV 99
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
R+ +LL+ + + ++ E T LL+ + E ++ E+ ++T K +A+
Sbjct: 100 CRE-QLLEREEEIAELKAERNNTRLLLE--HLECLVSRHERSLRMTVVKRQAQSPAG-VS 155
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+EV L A K K ERL + + + EEL T ++ K++ +Q+
Sbjct: 156 SEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKK- 214
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
L V D+ EN + +S + + + ++
Sbjct: 215 TLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLA 274
Query: 271 QLEE---ESEARLDLERQ-LVKA---NGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXX 323
L E E LD R+ L+K+ N ++ + +Y
Sbjct: 275 SLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRY-LAAQ 333
Query: 324 XXXXXXXTLIAKINNVEKQKSRLQSEVE----VLIIDLEKANGTARELQKRTEQLERVNI 379
L K+ N K + + E L LE A ++ ++ E L V
Sbjct: 334 REATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEA 393
Query: 380 EIKSR---LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
E+ R L + + + + LR + +L+ + EL + R+++ NK++ D
Sbjct: 394 ELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSD 449
>Z98946-1|CAB46379.1| 577|Homo sapiens moesin protein.
Length = 577
Score = 48.8 bits (111), Expect = 5e-05
Identities = 36/169 (21%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 57 IEREKAD-LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
+ R K D + VQ ++ R E+ + E N K+ E+ + K E + E EE
Sbjct: 292 MRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK--EKIEREKEELME 349
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LK+ ++ Q+++++ T+ E+E+ + Q+E +L + + + K + +
Sbjct: 350 RLKQIEEQTK-KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASR 408
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ T +L +++ EL I + +Q+ E +E ++ Q ++ ++E
Sbjct: 409 DQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLE 457
Score = 39.5 bits (88), Expect = 0.028
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
A + N +K++ + E E I+ EK EL +R +Q+E + + LEE +
Sbjct: 321 AMLENEKKKREMAEKEKEK--IEREK-----EELMERLKQIEEQTKKAQQELEEQTRRAL 373
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDAL---ARENKKMGDDLHDARANIT 442
+ +++ + Q+E ++++ E + E K+AL +R+ KK + L A +T
Sbjct: 374 ELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELT 425
Score = 38.7 bits (86), Expect = 0.048
Identities = 32/124 (25%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERL---EEAEGGAESQFEINRKRDTELLKLRKLL 103
LE+E++ R+ E+EK + + +L ERL EE A+ + E +R EL + RK
Sbjct: 323 LENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERK-- 380
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
++ A L K+ QE + +E + Q ++ + + +++ + AE+ ++Q+E
Sbjct: 381 -----RAQSEAEKLAKERQE-AEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMA 434
Query: 164 TKEK 167
++K
Sbjct: 435 RQKK 438
Score = 35.9 bits (79), Expect = 0.34
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
+ L ++E++ + Q +LE + +E+E+ + +L++ +EAE E+ + +
Sbjct: 348 MERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQAS 407
Query: 90 R--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
R K+ E L L + E A KK+++ + + Q+ Q K RAE + +
Sbjct: 408 RDQKKTQEQLALEMAELTARISQLEMAR-QKKESEAVEWQQKAQMVQEDLEKTRAELKTA 466
Query: 148 KFQAEVYE 155
V E
Sbjct: 467 MSTPHVAE 474
Score = 33.1 bits (72), Expect = 2.4
Identities = 24/137 (17%), Positives = 51/137 (37%)
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + AEKEK K + E EL+ +++ + ++ + E EL + +
Sbjct: 328 KKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAE 387
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ +Q + L++ +D K E + +++ ++
Sbjct: 388 KLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQ 447
Query: 257 SLHQVEIDLESVRVQLE 273
V+ DLE R +L+
Sbjct: 448 KAQMVQEDLEKTRAELK 464
Score = 32.3 bits (70), Expect = 4.2
Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAR-ELQKRTEQLERVNIEIKSRLEE 387
L+ ++ +E+Q + Q E+E ++LE+ A+ E +K ++ + E K L +
Sbjct: 347 LMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAE-EAKEALLQ 405
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA----RENKKMGDDLHDARANI 441
+ ++TQ L + EL +L+ R++K++ A ++ + + +DL RA +
Sbjct: 406 ASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAEL 463
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 48.8 bits (111), Expect = 5e-05
Identities = 47/222 (21%), Positives = 106/222 (47%), Gaps = 18/222 (8%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERE-----LRQRIERE---KADLSVQVIQL 71
T + E ++ ++++ D +R +++ L+ ER+ LR+ I R+ + +L + + L
Sbjct: 1671 TQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHL 1730
Query: 72 SERLEEAEG----GAESQFEI-NRKRDTELLKLRKLLEDVHLESE-ETAHLLKKKNQEIV 125
E E + +E EI N ++D E +D+ ++ E AH+ K+ QE +
Sbjct: 1731 KEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETI 1790
Query: 126 IDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELH 185
+ + + T + +K+ A++ E + +++ + IT+ K + +SE+
Sbjct: 1791 DKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEM- 1849
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
E+L + I D + +L EN+ L +E+ + +++V+
Sbjct: 1850 ---EQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVM 1888
Score = 47.6 bits (108), Expect = 1e-04
Identities = 88/452 (19%), Positives = 190/452 (42%), Gaps = 52/452 (11%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLS--VQVIQLSERLEEA 78
D+ E S+ + L ED+I+ +Q+ ++S Q++E K DLS ++ I+ +++++
Sbjct: 572 DLENELSSKVELLREKEDQIKKLQEYIDS-----QKLENIKMDLSYSLESIEDPKQMKQT 626
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
AE+ ++ KR++ L+ L ++ + +E A K+ +I + +Q Q++ K
Sbjct: 627 LFDAET-VALDAKRESAFLRSENL--ELKEKMKELATTYKQMENDIQL-YQSQLEAKKKM 682
Query: 139 KARAEKEKSKFQAEVYELLAQVEN-VTKE---------KIT-----ISKTCERLE----- 178
+ EKE E+ +L + ++ V K+ KIT ++K E E
Sbjct: 683 QVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREE 742
Query: 179 -ITISELHI---KIEELNRTIVD-------ITSHKQRLSQENIELVKEVQDLKVNIENVV 227
I +SEL ++E L + I D ITS K +L E + VQ L +E +
Sbjct: 743 VILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGL---LEEIG 799
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ-VEIDLESVRVQLEEESEARLDLERQL 286
K +A+ +LH E + V + E ++ ++L ++
Sbjct: 800 KTKDDLAT-----TQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEA 854
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRL 346
K + +G +++ + + + + VE++K+ +
Sbjct: 855 QKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENR-DSPLQTVEREKTLI 913
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
+++ + +++ +L++ E L+ ++KS + +TV + TQ LRN L
Sbjct: 914 TEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL 973
Query: 407 QRVSHELDKTREQKDALARENKKMGDDLHDAR 438
++ ++ + + N M ++ + +
Sbjct: 974 KQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Score = 46.0 bits (104), Expect = 3e-04
Identities = 64/415 (15%), Positives = 177/415 (42%), Gaps = 35/415 (8%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
++++RL+ D+L+ ++E+ + + ++ + +RL E E + + + +++ +L
Sbjct: 1084 QEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1143
Query: 97 LKLRKLLEDVHLESEETAHLLKK-KNQEIVIDFQ---------------EQIDQLTKTKA 140
L +++ + ++ + E +L + KN+E+ ++ E++ +TK +
Sbjct: 1144 LNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERK 1203
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
++ + F+ E L + + + + + I + E I+EL R++ + T+
Sbjct: 1204 VLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTA 1263
Query: 201 ---HKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
+ Q L + + +L +E+ L E + +K +++ +
Sbjct: 1264 QIINTQDLEKSHTKLQEEIPVLHEEQELLPNVK-KVSETQETMNELELLTEQSTTKDSTT 1322
Query: 258 LHQVEIDLESVRVQLEEESE--ARLDLER---QLVKANGEIGHWRSKFXXXXXXXXXXXX 312
L ++E++ + + +E E L ER + +K E+ H + K
Sbjct: 1323 LARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQES 1382
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVE-KQKSRLQSEVEVLIID--LEKANGTARELQK 369
+ S +++++ + K + L+ E+E+L + L++++ + + K
Sbjct: 1383 QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAK 1442
Query: 370 RTEQLERV-------NIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ L+R+ + ++K ++E V + +T+ +L+ L+ +++ R
Sbjct: 1443 EKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELR 1497
Score = 45.2 bits (102), Expect = 6e-04
Identities = 75/428 (17%), Positives = 179/428 (41%), Gaps = 32/428 (7%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKAD--LSVQVIQLSERLEEA 78
D ++ ++S L L + DLE+E + + REK D +Q S++LE
Sbjct: 547 DQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENI 606
Query: 79 EGGAESQFEINRKRDTELLKLRKL-LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTK 137
+ + + + D + +K E V L+++ + L+ +N E+ +E++ +L
Sbjct: 607 K--MDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLEL----KEKMKELAT 660
Query: 138 TKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIV 196
T + E + +Q +Q+E K ++ + K + I++L I+ ++ + ++
Sbjct: 661 TYKQMENDIQLYQ-------SQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 713
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ +++ EL KEV++ + E V+ L S+
Sbjct: 714 CNLELEGKITDLQKELNKEVEENEALREEVILL-----SELKSLPSEVERLRKEIQDKSE 768
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
LH + + + + ++ + L ++ K ++ +S +
Sbjct: 769 ELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNY-KSTDQEFQNFKTLHM 827
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL----EKANGTARELQKRTE 372
+ + +I N+ K+ + S + L +L ++ RE+Q+R
Sbjct: 828 DFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLN 887
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNK--QT--ELQRVSHELDKTREQKDALARENK 428
++E++ ++++R + +Q E+ + + K QT E++ ++ E D ++ +++L E
Sbjct: 888 EMEQLKEQLENR-DSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERD 946
Query: 429 KMGDDLHD 436
++ D+HD
Sbjct: 947 QLKSDIHD 954
Score = 44.0 bits (99), Expect = 0.001
Identities = 72/422 (17%), Positives = 175/422 (41%), Gaps = 29/422 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLS--VQVIQLS-ERLEEAEGGAESQFE 87
SAL +E K+ + + L+ +E Q + +EK ++ + +Q+ ++L+E ++ +
Sbjct: 1562 SALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMK 1621
Query: 88 INRKRDTELLKL-------RKLLEDVHLESEETAHLLKKKNQEIV-IDFQEQIDQLTKTK 139
+++++ + LK+ K+ E HL+ + L +N E I + + + +
Sbjct: 1622 ESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEM 1681
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLE-ITISELHIK-----IEEL 191
KE+ ++ V E L + KE + TI++ E+ E + I +H+K I++L
Sbjct: 1682 RSVTKERDDLRS-VEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKL 1740
Query: 192 NRTIVDITSHKQRLSQ--ENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
+ + T+ + + E+ + QDLK+ E + + Q
Sbjct: 1741 RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQ-EELRIAHMHLKEQQETIDKLRGIVSE 1799
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX--XXXXXX 307
L ++ DLE+ +L+E+ + E QL+ ++ + K
Sbjct: 1800 KTD----KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQ 1855
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAREL 367
K + ++ +V K++ L+ E L ++ ++ + +E
Sbjct: 1856 IKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQET 1915
Query: 368 QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALAREN 427
+ R ++++ + +E + ++ + + K ++ + +LDK++++ +E
Sbjct: 1916 KARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL 1975
Query: 428 KK 429
+K
Sbjct: 1976 QK 1977
Score = 42.3 bits (95), Expect = 0.004
Identities = 83/425 (19%), Positives = 179/425 (42%), Gaps = 37/425 (8%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE-----INRKRDTELL 97
+++ LES ++ ++ I K+ +S +V + + +EE G + +F+ I++K+D E
Sbjct: 966 LRNALESLKQHQETINTLKSKISEEVSR-NLHMEENTGETKDEFQQKMVGIDKKQDLEAK 1024
Query: 98 KLRKLLEDVH----LESEETAH-LLKKKNQ-----EIVIDFQEQIDQLTKTKARA----E 143
+ L DV +E + L+++KN+ E VI +EQ+ K +
Sbjct: 1025 NTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQ 1084
Query: 144 KEKSKFQAEV---YELLAQVEN-VTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
+E E+ E++AQ +N K++ +S+TC+RL +E+ K++E ++ + +
Sbjct: 1085 EELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRL----AEVEEKLKEKSQQLQEKQ 1140
Query: 200 SHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
+ +E E+ K++ +++ N++N + K S+
Sbjct: 1141 QQLLNVQEEMSEMQKKINEIE-NLKNELKNKELTLEHMETERLELAQKLNENYEEVKSIT 1199
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+ L+ ++ E E + R+ ++A G K +
Sbjct: 1200 KERKVLKELQKSFETERDHLRGYIRE-IEATGLQTKEELKIAHIHLKEHQETIDELRRSV 1258
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVL--IIDLEKANGTARELQKRTEQLERV 377
L ++++ L E E+L + + + T EL+ TEQ
Sbjct: 1259 SEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTK 1318
Query: 378 NIEIKSRLE-ETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ +R+E E ++L E+ Q Q E++ ++ E D + K+AL ++ ++ + + +
Sbjct: 1319 DSTTLARIEMERLRLNEKFQ----ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE 1374
Query: 437 ARANI 441
A I
Sbjct: 1375 TLAKI 1379
Score = 42.3 bits (95), Expect = 0.004
Identities = 83/405 (20%), Positives = 162/405 (40%), Gaps = 29/405 (7%)
Query: 40 IRLIQDDLESERELRQRIEREKA-DLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLK 98
I+ I + E+ EL+Q E KA D ++Q I+ S+ LE ESQ EI + E +
Sbjct: 1537 IKQISEVQENVNELKQFKEHRKAKDSALQSIE-SKMLELTNRLQESQEEI-QIMIKEKEE 1594
Query: 99 LRKLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAEVYELL 157
++++ E + +E ++ LK+ +EIV +E Q + K A E + E+ L
Sbjct: 1595 MKRVQEALQIERDQ----LKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLK 1650
Query: 158 AQVENVTKEKITISK-TCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
Q E +K+ + E + +T LH +EE+ +T + L L E
Sbjct: 1651 EQFET---QKLNLENIETENIRLT-QILHENLEEMR----SVTKERDDLRSVEETLKVER 1702
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
LK N+ + + + + + ++ +++ LE +
Sbjct: 1703 DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762
Query: 277 EARLDLERQLVKANGEIGHWRSK-FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK 335
+A L + ++ I H K K S L K
Sbjct: 1763 DA-LKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEK 1821
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLE-ETVQLYEQ 394
I ++ + +L + L D+ + E+++ +Q++ ++ + S+LE E + L ++
Sbjct: 1822 IQELKANEHQLIT----LKKDVNETQKKVSEMEQLKKQIKDQSLTL-SKLEIENLNLAQE 1876
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+L E++ V E D R ++ L E ++ + L + +A
Sbjct: 1877 LHENLE----EMKSVMKERDNLRRVEETLKLERDQLKESLQETKA 1917
Score = 41.1 bits (92), Expect = 0.009
Identities = 73/399 (18%), Positives = 154/399 (38%), Gaps = 25/399 (6%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
LS L L ++ ++ +++ + E I EK L +V+ R++ G E EI
Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQ---GLLE---EIG 799
Query: 90 R-KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK 148
+ K D + D ++ +T H+ ++ ++V++ E+++Q KE K
Sbjct: 800 KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEI---VNLSKEAQK 856
Query: 149 FQAEVYEL-------LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
F + + L +++ T+E E+L+ + ++ + R IT
Sbjct: 857 FDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEK 916
Query: 202 KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQV 261
Q+ +E L +E DLK E++ + Q+ S SL Q
Sbjct: 917 LQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQH 976
Query: 262 EIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXX 321
+ + +++ ++ EE L +E + E ++ K +
Sbjct: 977 QETINTLKSKISEEVSRNLHMEENTGETKDE---FQQKMVGIDKKQDLEAKNT---QTLT 1030
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARE-LQKRTEQLERVNIE 380
KI ++ ++K+ LQ +E +I + E+ +E ++ E E + +
Sbjct: 1031 ADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRL- 1089
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+ L++ ++ Q + K+ EL R L + E+
Sbjct: 1090 LGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEK 1128
Score = 39.9 bits (89), Expect = 0.021
Identities = 41/226 (18%), Positives = 101/226 (44%), Gaps = 10/226 (4%)
Query: 73 ERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQI 132
+ L E E ++ ++EL LR +++ L+ E+ L+ + +E+ + +E+
Sbjct: 477 DTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQ----LRTEKEEMELKLKEKN 532
Query: 133 DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCER-LEITISELHIKIEEL 191
D L + +A K K + ++ ++ ++N+ K + ++ E L + L K +++
Sbjct: 533 D-LDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQI 591
Query: 192 NRTIVDITSHK-QRLSQE---NIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
+ I S K + + + ++E +++ + +K + + + +
Sbjct: 592 KKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLEL 651
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
+ Q+E D++ + QLE + + ++DLE++L A EI
Sbjct: 652 KEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEI 697
Score = 39.9 bits (89), Expect = 0.021
Identities = 72/392 (18%), Positives = 169/392 (43%), Gaps = 31/392 (7%)
Query: 30 LSALSRLEDK---IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF 86
++A++ ++K I +++ E+++ + IE E L+ Q+ L E LEE + +
Sbjct: 1633 MTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLT-QI--LHENLEEMRSVTKERD 1689
Query: 87 EINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI----DFQEQIDQLTKTKARA 142
++ +T ++ +L E+ L T L K++ +IV + QE ID+L +
Sbjct: 1690 DLRSVEETLKVERDQLKEN--LRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEK 1747
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT--- 199
E S Q ++ + + + + I + + + E I++L + + T
Sbjct: 1748 TNEISNMQKDLEH---SNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKL 1804
Query: 200 SHKQR-LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
S+ Q+ L N +L +++Q+LK N ++ LK + ++ +L
Sbjct: 1805 SNMQKDLENSNAKLQEKIQELKANEHQLITLKKDV-NETQKKVSEMEQLKKQIKDQSLTL 1863
Query: 259 HQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
++EI+ + L +E L+ + ++K + R + K
Sbjct: 1864 SKLEIE----NLNLAQELHENLEEMKSVMKERDNLR--RVEETLKLERDQLKESLQETKA 1917
Query: 319 SXXXXXXXXXXXTLIAKIN--NVEKQKSRLQSEVEVLIIDLEK-ANGTARELQKRTEQLE 375
+++K + V+K + ++ SE + I D++K + + ELQK+ ++L+
Sbjct: 1918 RDLEIQQELKTARMLSKEHKETVDKLREKI-SEKTIQISDIQKDLDKSKDELQKKIQELQ 1976
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
+ +++ R++E V + + ++ + + +
Sbjct: 1977 KKELQL-LRVKEDVNMSHKKINEMEQLKKQFE 2007
Score = 38.7 bits (86), Expect = 0.048
Identities = 80/411 (19%), Positives = 162/411 (39%), Gaps = 31/411 (7%)
Query: 33 LSRLEDKIRLIQDDLESE-RELRQRIEREKADLSVQVIQLSERLEEAE----GGAESQFE 87
L L+ +D L RE+ + K +L + I L E E + +E +
Sbjct: 1205 LKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQ 1264
Query: 88 INRKRDTEL--LKLRKLLEDVHLESEETAHLLK-KKNQEIVIDFQEQIDQLTK----TKA 140
I +D E KL++ + +H E E ++ K + QE + + + +Q T T A
Sbjct: 1265 IINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLA 1324
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
R E E+ + + E +++++TKE+ + E LE+ +L E + T+ I
Sbjct: 1325 RIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLK---EHIRETLAKIQE 1381
Query: 201 HKQRLSQENIELVKEVQDLKVNIENVVYL-KSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
+ + Q K+ + K+ E + K + S+
Sbjct: 1382 SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1441
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGE------IGHWRSK-FXXXXXXXXXXXX 312
+ + DL+ ++ L+ ES+ + +++V + E + H K
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLS 1501
Query: 313 XXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ----SEVEVLIIDLEKANGTARELQ 368
+ S L KI + +++ +L SEV+ + +L++ +
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNELKQFKEHRKAKD 1561
Query: 369 KRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+ +E +E+ +RL+E+ E+ Q ++ K+ E++RV L R+Q
Sbjct: 1562 SALQSIESKMLELTNRLQES---QEEIQIMIKEKE-EMKRVQEALQIERDQ 1608
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 48.8 bits (111), Expect = 5e-05
Identities = 87/384 (22%), Positives = 152/384 (39%), Gaps = 41/384 (10%)
Query: 67 QVIQLSERL----EEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
Q+ QL ER+ EE + E + +++T L ++ ++ + EE + NQ
Sbjct: 1841 QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM-NLLNQ 1899
Query: 123 EIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITIS 182
+I QE++ ++TK K AE+EK + + LA++ +I C+ ++
Sbjct: 1900 QI----QEELSRVTKLKETAEEEKDDLEERLMNQLAELNG------SIGNYCQ----DVT 1945
Query: 183 ELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXX 242
+ IK E L + ++ L +E +LVKE ++ I K Q A +
Sbjct: 1946 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2005
Query: 243 XXXXXXXXXXXXXASLHQVEID----------LESVRVQLE-EESEARLDLERQLVKAN- 290
+ Q++ D LE LE ++E++ DLE + K N
Sbjct: 2006 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE--ITKENL 2063
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
+ R K + + L +N E KS+++ +
Sbjct: 2064 AQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL---QSNKESVKSQMKQKD 2120
Query: 351 EVLIIDLEKANGT-ARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
E L LE+A +E + E+L+ + E K LEET+ + Q L K E+Q++
Sbjct: 2121 EDLERRLEQAEEKHLKEKKNMQEKLDALRRE-KVHLEETI---GEIQVTLNKKDKEVQQL 2176
Query: 410 SHELDKTREQKDALARENKKMGDD 433
LD T Q A + + DD
Sbjct: 2177 QENLDSTVTQLAAFTKSMSSLQDD 2200
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/400 (19%), Positives = 153/400 (38%), Gaps = 20/400 (5%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
R++ D+L+ ++EL+ E K+ + + L RLE+AE E + + +L LR
Sbjct: 2093 RVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAE---EKHLKEKKNMQEKLDALR 2149
Query: 101 KLLEDVHLESE--ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA 158
+ E VHLE E L KK++E V QE +D A K S Q + ++
Sbjct: 2150 R--EKVHLEETIGEIQVTLNKKDKE-VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2206
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ + + K + + + EI + E + + + + I + +++ +E K++ +
Sbjct: 2207 EAKK-WERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE 2265
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
K E V L+ ++ H + +L + +L+ +
Sbjct: 2266 SKAQTE--VQLQQKVCDTLQGENKELLSQLEETRHL---YHSSQNELAKLESELKSLKDQ 2320
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
DL L K + G+ + L +IN
Sbjct: 2321 LTDLSNSLEKCKEQKGNLEG-IIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2379
Query: 339 VEKQ----KSRLQSEVEVLIIDL-EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
E++ S + ++V I +L ++ + +EL+ Q E NI ++ ++ V
Sbjct: 2380 KEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN 2439
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
Q L+ + E + +LD + +L + ++ D
Sbjct: 2440 QLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGD 2479
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/190 (20%), Positives = 86/190 (45%), Gaps = 4/190 (2%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+Q++L R +R+ + AD+ QV ++ + G E K TE+ R L
Sbjct: 1502 LQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD--RSL 1559
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
LE+ L S + LK + + D ++ + ++ K+ E +++Q + EL + E
Sbjct: 1560 LENQSLSS--SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEI 1617
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+ + +S ER++ + + + +EL + ++K+ ++ E +E++++K
Sbjct: 1618 LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Query: 223 IENVVYLKSQ 232
+ K Q
Sbjct: 1678 MRKFAKSKQQ 1687
Score = 44.0 bits (99), Expect = 0.001
Identities = 87/435 (20%), Positives = 177/435 (40%), Gaps = 34/435 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEI 88
++ L+ L I D+ + + +E E +L V +L E ++ + + + EI
Sbjct: 1927 MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI------VIDFQEQIDQLTKTKARA 142
RK E ++ + ++E LLK+K QE+ I +QE+I L +T
Sbjct: 1987 -RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKAL 2045
Query: 143 EKEKSKFQAEVY---ELLAQ-VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
E +++ Q ++ E LAQ VE+ K + ++ L+ T SE + + + ++
Sbjct: 2046 EFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL 2105
Query: 199 TSHKQ----RLSQENIELVKEVQDLKVNI----ENVVYLKSQIASQXXXXXXXXXXXXXX 250
S+K+ ++ Q++ +L + ++ + +N+ + +
Sbjct: 2106 QSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVT 2165
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
+ Q++ +L+S QL +++ L+ + E W KF
Sbjct: 2166 LNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2225
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR 370
S + N+ SRL+ + ++ KA + QK
Sbjct: 2226 IRLKEDNCSVLKDQLRQMSIHMEELKINI----SRLEHDKQIWE---SKAQTEVQLQQKV 2278
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQR-------VSHELDKTREQKDAL 423
+ L+ N E+ S+LEET LY +Q +L ++EL+ +S+ L+K +EQK L
Sbjct: 2279 CDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNL 2338
Query: 424 ARENKKMGDDLHDAR 438
++ D+ +++
Sbjct: 2339 EGIIRQQEADIQNSK 2353
Score = 43.2 bits (97), Expect = 0.002
Identities = 48/204 (23%), Positives = 88/204 (43%), Gaps = 8/204 (3%)
Query: 32 ALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+LS + ++L + L ++E L + IE K+ + + E+ +E + E +
Sbjct: 1564 SLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYE 1623
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKS 147
E +++ ++E V E +E L+ +E QE ++ + K + K
Sbjct: 1624 NVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAK 1683
Query: 148 KFQAEVYELLAQVENVTKEKITISKTC-ERLEITISELHIKIEELNRTIVD---ITSHKQ 203
Q ++ EL + + + E T E +E +S EEL R ++ ++ Q
Sbjct: 1684 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQ 1743
Query: 204 RLSQENIELVKEVQDLKVNIENVV 227
L E L +EVQDLK IE+ V
Sbjct: 1744 SLMSEKDSLSEEVQDLKHQIEDNV 1767
Score = 42.3 bits (95), Expect = 0.004
Identities = 82/442 (18%), Positives = 174/442 (39%), Gaps = 34/442 (7%)
Query: 26 YSADLSALSRLED--KIRLIQDDLESER-ELRQRIEREKADL---SVQVIQLSERLEEAE 79
+S D SAL +I+ ++E+E+ EL ++ ++L S +V QL E++ +
Sbjct: 1291 HSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQG 1350
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL--LKKKN---QEIVIDFQEQIDQ 134
ES ++ + + L++ LE L+ HL L+ K Q+++ +E +
Sbjct: 1351 LEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSY 1410
Query: 135 LTKTKARAEKEKSKFQAEVYE-------LLAQVENVTKEKITISKTCERLEITISELHIK 187
L+ + E +K Q E+ E L Q+E KE + ++L++ + E+ K
Sbjct: 1411 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQK 1467
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
EE+ +++L I + +++ K E + + I
Sbjct: 1468 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1527
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGE--------IGHWRSK 299
L ++ + L+ R +L E + L LE Q + ++ E + + K
Sbjct: 1528 SAQNKEKDTVLGRLAL-LQEERDKLITEMDRSL-LENQSLSSSCESLKLALEGLTEDKEK 1585
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
++ L+ NV + R+Q VE + + ++
Sbjct: 1586 LVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQE 1645
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
G R + ++ E+ E + +EE + E+ ++ ++KQ ++ + E D+ R +
Sbjct: 1646 LYGKLRSTEANKKETEKQLQEAEQEMEE---MKEKMRKFAKSKQQKILELEEENDRLRAE 1702
Query: 420 KDALARENKKMGDDLHDARANI 441
K+ + L + A++
Sbjct: 1703 VHPAGDTAKECMETLLSSNASM 1724
Score = 41.9 bits (94), Expect = 0.005
Identities = 76/415 (18%), Positives = 165/415 (39%), Gaps = 28/415 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LS+LE+ L S+ EL ++E E L Q+ LS LE+ + + I R++
Sbjct: 2290 LSQLEETRHLYHS---SQNELA-KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2345
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ ++ + E + + + + L + ++EI + Q+ I L + KE++ Q
Sbjct: 2346 EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLL------SGKEEA-IQVA 2398
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQRLSQENIE 211
+ EL Q + KE + E I + E + K +++ N+ + + + K+ Q+ +
Sbjct: 2399 IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQ 2458
Query: 212 L---VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
L VK + L+ + + +V Q+ + A ++++ ++ +
Sbjct: 2459 LDSFVKSMSSLQNDRDRIVGDYQQLEER---HLSIILEKDQLIQEAAAENNKLKEEIRGL 2515
Query: 269 RVQLEEESEARLDLERQLVKANGEIGH-------WRSKFXXXXXXXXXXXXXXXXKYSXX 321
R +++ + L+ +L++ ++ + + K
Sbjct: 2516 RSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEK 2575
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR-TEQLERVNIE 380
L N ++++K L E+E L + + + LQ+ T L ++
Sbjct: 2576 LKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLK 2635
Query: 381 IK-SRLEETVQLYEQTQRDLRNKQTELQRVSHE-LDKTREQKDALARENKKMGDD 433
+K + L+ +Q+ + + EL V E K E +D L +E K + D
Sbjct: 2636 VKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHD 2690
Score = 40.3 bits (90), Expect = 0.016
Identities = 63/384 (16%), Positives = 142/384 (36%), Gaps = 14/384 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE++ + D E + I++E Q+ + + + + + + E
Sbjct: 2427 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRI--VGDYQQLE 2484
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +LE L E A K +E + + +D L A+ + E +++ ++ +
Sbjct: 2485 ERHLSIILEKDQLIQEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2542
Query: 156 LLAQVENVTKEKITIS-KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
++ ++ K+ + + + + LE ++L K++E D+ L +E +L K
Sbjct: 2543 VITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2602
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
E++ LKV+I L Q+ + +H++ S + ++ E
Sbjct: 2603 EIESLKVSISQ---LTRQVTA--LQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAE 2657
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
E + ++++ K GEI K +
Sbjct: 2658 LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2717
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ V K+ L ++++ + + + ++L+R + + L+E QL EQ
Sbjct: 2718 KLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKR---KYDASLKELAQLKEQ 2774
Query: 395 TQRDLRNKQTELQRVSHELDKTRE 418
+ R + L + ++ T E
Sbjct: 2775 GLLN-RERDALLSETAFSMNSTEE 2797
Score = 39.5 bits (88), Expect = 0.028
Identities = 69/421 (16%), Positives = 160/421 (38%), Gaps = 21/421 (4%)
Query: 21 DVNIEYSADL-SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+V ++ + +L + ++LE+K++ ++ E R ++ EK DLS ++ L + +
Sbjct: 2556 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2615
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
++ ++ L L V E L +Q+ + + +E++ + K
Sbjct: 2616 R------QVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEA 2669
Query: 140 ARAEKE-KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
A+ E + K + E+ L + E T + L + E+ K+ + + +
Sbjct: 2670 AKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGL 2729
Query: 199 TSHKQRLSQENIELV-------KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXX 251
T+ Q + L +E+ +LK + + +Q+ Q
Sbjct: 2730 TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETA 2789
Query: 252 XXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX-- 309
++ LE + QL + E L L QL + ++ +
Sbjct: 2790 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLW 2849
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
K T A++ +++K S LQ++ + L+ +L+ ++ +
Sbjct: 2850 NELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2909
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+L + +++ ++T + ++ Q +LR + Q HEL + R +K + ++
Sbjct: 2910 EITELHPLKAQLQEYQDKT-KAFQIMQEELRQENLSWQ---HELHQLRMEKSSWEIHERR 2965
Query: 430 M 430
M
Sbjct: 2966 M 2966
Score = 38.3 bits (85), Expect = 0.064
Identities = 68/431 (15%), Positives = 173/431 (40%), Gaps = 21/431 (4%)
Query: 21 DVNIEYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLS---VQVIQLSE 73
DV +++S + + S+L++K + + E R + ++E LS +++ ++ +
Sbjct: 821 DVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQ 880
Query: 74 RLEEAEGGAESQFEINRKRDTELLKLRKLLED--VHLESEETAHLLKKKNQEIVIDFQEQ 131
L E + E+ + ++D ++ ++ + + V L E+ + ++ K + ++ +
Sbjct: 881 LLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSR 940
Query: 132 IDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL 191
++ K + + E S + Y+ ++ ++KE++ + E + ++ +
Sbjct: 941 AEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALI 1000
Query: 192 NRTIVDITSHKQRLSQENIELVKEVQ-DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXX 250
NR ++ RL +E L E + ++ ++ ++ ++
Sbjct: 1001 NRK--ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEI 1058
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
++ + E++L+ +R LEE+ A + LVK + ++
Sbjct: 1059 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQA-LVKQMNQTLQDKTNQIDLLQAEISE 1117
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR 370
K + K V SE ++ EK L+K
Sbjct: 1118 NQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELE-EKILA----LEKE 1172
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
EQL++ +++ L + ++ Q R+ + EL++ + ++ +EQ D ++EN+ +
Sbjct: 1173 KEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1229
Query: 431 GDDLHDARANI 441
GD L + +
Sbjct: 1230 GDQLRQLQIQV 1240
Score = 38.3 bits (85), Expect = 0.064
Identities = 80/424 (18%), Positives = 164/424 (38%), Gaps = 40/424 (9%)
Query: 30 LSALSRLEDKIRLIQDDLESEREL----RQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
L +SRLE+++ ++D+ + E L R +E +K + ++ + +E E +
Sbjct: 1006 LQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQT 1065
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+++ EL +RK LE+ E+ L+K+ NQ + Q++ +Q+ +A +
Sbjct: 1066 IS---EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTL----QDKTNQIDLLQAEISEN 1118
Query: 146 KSKFQAEVYELLAQVEN----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++ Q + + + KE + IS C T S H K EL I+ +
Sbjct: 1119 QAIIQKLITSNTDASDGDSVALVKETVVISPPC-----TGSSEHWK-PELEEKILALEKE 1172
Query: 202 KQRLSQENIE-LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
K++L ++ E L LK E +L+ ++ Q
Sbjct: 1173 KEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKEN----EN 1228
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX------ 314
+ L +++Q+ E + +L Q + G F
Sbjct: 1229 IGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDW 1288
Query: 315 -XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ A++ +E +K L+ +V +L K + +LQ EQ
Sbjct: 1289 PSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQ---EQ 1345
Query: 374 LERVNIEIKS--RLEETVQLY-EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +EI+S + +++ E Q+ L + Q ++ + H L + + + D L + K
Sbjct: 1346 INKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH-LRELQPKLDELQKLISKK 1404
Query: 431 GDDL 434
+D+
Sbjct: 1405 EEDV 1408
Score = 37.5 bits (83), Expect = 0.11
Identities = 85/414 (20%), Positives = 166/414 (40%), Gaps = 35/414 (8%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDTE 95
E +++ + ++E +E ++ + K +++ + ++RL E ++ E +
Sbjct: 1661 EKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1720
Query: 96 LLKLRKLLEDVHLE----SEETAHLLKKKNQ--EIVIDFQEQIDQLTKTKARAEK-EKSK 148
+++ LE V +E S++ L+ +K+ E V D + QI+ +A E EK
Sbjct: 1721 NASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEDNVSKQANLEATEKHD 1780
Query: 149 FQAEVYELLAQ-VENVTKEKITISK----TCERLEITISELHIKIEELNRTIVDITSHKQ 203
Q V E Q + T+E+ ++S TC + + + + + +I ++ Q
Sbjct: 1781 NQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ 1840
Query: 204 RLSQ--ENIE-LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
++ Q E I L +E Q K + + K+ + SQ Q
Sbjct: 1841 QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQ 1900
Query: 261 VEIDLESVRVQLEEESEARLDLER----QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
++ +L V E E + DLE QL + NG IG++
Sbjct: 1901 IQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL------- 1953
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L + + K+K++++SE+ LEK G +E ++ E
Sbjct: 1954 -LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY--LEKIQGAQKEPGNKSHAKEL 2010
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD--KTREQKD-ALAREN 427
+ +K + +E QL + R + K + L+R L+ +T QKD + +EN
Sbjct: 2011 QEL-LKEKQQEVKQLQKDCIR-YQEKISALERTVKALEFVQTESQKDLEITKEN 2062
Score = 31.9 bits (69), Expect = 5.5
Identities = 38/200 (19%), Positives = 87/200 (43%), Gaps = 8/200 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+ RL+ + + D+L +E+ IE + D+ ++V+Q L++ + Q
Sbjct: 774 AEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQ--NELDDVQLQFSEQST 831
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ R ++L + E LE E + K +E+ ++ ++TK ++K
Sbjct: 832 LIRSLQSQL----QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR 887
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
+ + + + VT+ ++++ +L L ++I+ L + ++ S + +
Sbjct: 888 DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQL-NLLSRAEEAKK 946
Query: 208 ENIELVKEVQD-LKVNIENV 226
E +E EV LK N + +
Sbjct: 947 EQVEEDNEVSSGLKQNYDEM 966
>M69066-1|AAA36322.1| 577|Homo sapiens moesin B protein.
Length = 577
Score = 48.8 bits (111), Expect = 5e-05
Identities = 36/169 (21%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 57 IEREKAD-LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
+ R K D + VQ ++ R E+ + E N K+ E+ + K E + E EE
Sbjct: 292 MRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK--EKIEREKEELME 349
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LK+ ++ Q+++++ T+ E+E+ + Q+E +L + + + K + +
Sbjct: 350 RLKQIEEQTK-KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASR 408
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ T +L +++ EL I + +Q+ E +E ++ Q ++ ++E
Sbjct: 409 DQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLE 457
Score = 39.5 bits (88), Expect = 0.028
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
A + N +K++ + E E I+ EK EL +R +Q+E + + LEE +
Sbjct: 321 AMLENEKKKREMAEKEKEK--IEREK-----EELMERLKQIEEQTKKAQQELEEQTRRAL 373
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDAL---ARENKKMGDDLHDARANIT 442
+ +++ + Q+E ++++ E + E K+AL +R+ KK + L A +T
Sbjct: 374 ELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELT 425
Score = 38.7 bits (86), Expect = 0.048
Identities = 32/124 (25%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERL---EEAEGGAESQFEINRKRDTELLKLRKLL 103
LE+E++ R+ E+EK + + +L ERL EE A+ + E +R EL + RK
Sbjct: 323 LENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERK-- 380
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
++ A L K+ QE + +E + Q ++ + + +++ + AE+ ++Q+E
Sbjct: 381 -----RAQSEAEKLAKERQE-AEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMA 434
Query: 164 TKEK 167
++K
Sbjct: 435 RQKK 438
Score = 35.9 bits (79), Expect = 0.34
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
+ L ++E++ + Q +LE + +E+E+ + +L++ +EAE E+ + +
Sbjct: 348 MERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQAS 407
Query: 90 R--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
R K+ E L L + E A KK+++ + + Q+ Q K RAE + +
Sbjct: 408 RDQKKTQEQLALEMAELTARISQLEMAR-QKKESEAVEWQQKAQMVQEDLEKTRAELKTA 466
Query: 148 KFQAEVYE 155
V E
Sbjct: 467 MSTPHVAE 474
Score = 33.1 bits (72), Expect = 2.4
Identities = 24/137 (17%), Positives = 51/137 (37%)
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + AEKEK K + E EL+ +++ + ++ + E EL + +
Sbjct: 328 KKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAE 387
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ +Q + L++ +D K E + +++ ++
Sbjct: 388 KLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQ 447
Query: 257 SLHQVEIDLESVRVQLE 273
V+ DLE R +L+
Sbjct: 448 KAQMVQEDLEKTRAELK 464
Score = 32.3 bits (70), Expect = 4.2
Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAR-ELQKRTEQLERVNIEIKSRLEE 387
L+ ++ +E+Q + Q E+E ++LE+ A+ E +K ++ + E K L +
Sbjct: 347 LMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAE-EAKEALLQ 405
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA----RENKKMGDDLHDARANI 441
+ ++TQ L + EL +L+ R++K++ A ++ + + +DL RA +
Sbjct: 406 ASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAEL 463
>D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.
Length = 1530
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/201 (21%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ ++ +Q + S + ++ EK L + EE + GA + E + +E
Sbjct: 750 LQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGAR-RLEEGTEETSE 808
Query: 96 LLKLRKLLEDVHLESEETAHL------LKKKNQEIVIDFQEQ---IDQLTKTKARAEKEK 146
L+ KL E++ ++S + HL LKK+ Q+I F +Q ++ + ++
Sbjct: 809 TLE--KLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLI 866
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
S+ +A L ++++ + +E + + E +S LH ++ ++ + + D+ H Q
Sbjct: 867 SELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQ 926
Query: 207 QENIELVKEVQDLKVNIENVV 227
+E E+ +Q L+ + E +V
Sbjct: 927 KERDEMETHLQSLQFDKEQMV 947
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/189 (22%), Positives = 80/189 (42%), Gaps = 8/189 (4%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A + +E+ ++ ++ E ERE QR+ A L Q+ Q+ L + + Q E ++
Sbjct: 662 AKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQ----RDQQLEALQQ 717
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+L+K L ++ E++ L+ E+ Q ++ +L A E Q
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTHYDEL----QARLGELQGEAASREDTICLLQN 773
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
E L A ++ K + + RLE E +E+L + + + L QE
Sbjct: 774 EKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAA 833
Query: 212 LVKEVQDLK 220
L K++Q +K
Sbjct: 834 LKKQMQKIK 842
Score = 44.8 bits (101), Expect = 7e-04
Identities = 61/334 (18%), Positives = 124/334 (37%), Gaps = 15/334 (4%)
Query: 110 SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKIT 169
+EET+ L+K +E+ I Q++ L + A +K+ K + + + VE ++ +
Sbjct: 803 TEETSETLEKLREELAIK-SGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATS 861
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYL 229
+ L+ T L +++EL + ++ + K+ E L +EV ++ +++ L
Sbjct: 862 KDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVR---QHMADL 918
Query: 230 KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE-ESEARLDLERQLVK 288
+ + S + E + E+++ Q+EE + EAR + Q K
Sbjct: 919 EGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEAN-EALKKQIEELQQEARKAITEQKQK 977
Query: 289 ANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQS 348
+G + S A++ + Q S
Sbjct: 978 MR-RLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDS 1036
Query: 349 EVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQR 408
+ + E+ ELQ + ++ L+E + L Q + R K EL+
Sbjct: 1037 SLALH----ERIQALEAELQA----VSHSKTLLEKELQEVIALTSQELEESREKVLELED 1088
Query: 409 VSHELDKTREQKDALARENKKMGDDLHDARANIT 442
E R++ L NKK+ +L + +T
Sbjct: 1089 ELQESRGFRKKIKRLEESNKKLALELEHEKGKLT 1122
Score = 40.7 bits (91), Expect = 0.012
Identities = 56/245 (22%), Positives = 114/245 (46%), Gaps = 31/245 (12%)
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLES-EETAHLLKKKNQE 123
S++ + + E + G E E+ +RD+ + LE E+ EE +LK+K +
Sbjct: 360 SIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS--LESSAAETQEEMLQVLKEKMR- 416
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSKFQAEV----YELLAQVE----------NVTKEKIT 169
+ Q++ L+ ++A KEK++ QA++ +L AQVE +++ E T
Sbjct: 417 ----LEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDT 472
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK---VNIENV 226
+ ++C LE +++L +E N ++ + Q ++ L+ +V+D++ ++ +N
Sbjct: 473 LKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNT 532
Query: 227 VY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR----VQLEEESEARLD 281
V+ L+ Q+ + AS ++ L+SVR QL EAR+
Sbjct: 533 VHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEIS-SLQSVRQWYQQQLALAQEARVR 591
Query: 282 LERQL 286
L+ ++
Sbjct: 592 LQGEM 596
Score = 33.5 bits (73), Expect = 1.8
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 134 QLTKTKARAEKEKSKFQAEVYELLAQV--ENVTKEKITISKTC--ERLEITISELHIKIE 189
QLT+T+ R+ KEK + A++ + A + + +I +KT E L+ + E + E
Sbjct: 623 QLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERE 682
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
L R S +Q+L Q + L++ Q L+ + + L Q+
Sbjct: 683 RLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQL 726
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 48.8 bits (111), Expect = 5e-05
Identities = 87/384 (22%), Positives = 152/384 (39%), Gaps = 41/384 (10%)
Query: 67 QVIQLSERL----EEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
Q+ QL ER+ EE + E + +++T L ++ ++ + EE + NQ
Sbjct: 1807 QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM-NLLNQ 1865
Query: 123 EIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITIS 182
+I QE++ ++TK K AE+EK + + LA++ +I C+ ++
Sbjct: 1866 QI----QEELSRVTKLKETAEEEKDDLEERLMNQLAELNG------SIGNYCQ----DVT 1911
Query: 183 ELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXX 242
+ IK E L + ++ L +E +LVKE ++ I K Q A +
Sbjct: 1912 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 1971
Query: 243 XXXXXXXXXXXXXASLHQVEID----------LESVRVQLE-EESEARLDLERQLVKAN- 290
+ Q++ D LE LE ++E++ DLE + K N
Sbjct: 1972 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE--ITKENL 2029
Query: 291 GEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV 350
+ R K + + L +N E KS+++ +
Sbjct: 2030 AQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL---QSNKESVKSQMKQKD 2086
Query: 351 EVLIIDLEKANGT-ARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
E L LE+A +E + E+L+ + E K LEET+ + Q L K E+Q++
Sbjct: 2087 EDLERRLEQAEEKHLKEKKNMQEKLDALRRE-KVHLEETI---GEIQVTLNKKDKEVQQL 2142
Query: 410 SHELDKTREQKDALARENKKMGDD 433
LD T Q A + + DD
Sbjct: 2143 QENLDSTVTQLAAFTKSMSSLQDD 2166
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/400 (19%), Positives = 153/400 (38%), Gaps = 20/400 (5%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
R++ D+L+ ++EL+ E K+ + + L RLE+AE E + + +L LR
Sbjct: 2059 RVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAE---EKHLKEKKNMQEKLDALR 2115
Query: 101 KLLEDVHLESE--ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLA 158
+ E VHLE E L KK++E V QE +D A K S Q + ++
Sbjct: 2116 R--EKVHLEETIGEIQVTLNKKDKE-VQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2172
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ + + K + + + EI + E + + + + I + +++ +E K++ +
Sbjct: 2173 EAKK-WERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE 2231
Query: 219 LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEA 278
K E V L+ ++ H + +L + +L+ +
Sbjct: 2232 SKAQTE--VQLQQKVCDTLQGENKELLSQLEETRHL---YHSSQNELAKLESELKSLKDQ 2286
Query: 279 RLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINN 338
DL L K + G+ + L +IN
Sbjct: 2287 LTDLSNSLEKCKEQKGNLEG-IIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2345
Query: 339 VEKQ----KSRLQSEVEVLIIDL-EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
E++ S + ++V I +L ++ + +EL+ Q E NI ++ ++ V
Sbjct: 2346 KEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN 2405
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
Q L+ + E + +LD + +L + ++ D
Sbjct: 2406 QLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGD 2445
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/190 (20%), Positives = 86/190 (45%), Gaps = 4/190 (2%)
Query: 43 IQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKL 102
+Q++L R +R+ + AD+ QV ++ + G E K TE+ R L
Sbjct: 1468 LQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD--RSL 1525
Query: 103 LEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
LE+ L S + LK + + D ++ + ++ K+ E +++Q + EL + E
Sbjct: 1526 LENQSLSS--SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEI 1583
Query: 163 VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN 222
+ + +S ER++ + + + +EL + ++K+ ++ E +E++++K
Sbjct: 1584 LLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1643
Query: 223 IENVVYLKSQ 232
+ K Q
Sbjct: 1644 MRKFAKSKQQ 1653
Score = 44.0 bits (99), Expect = 0.001
Identities = 87/435 (20%), Positives = 177/435 (40%), Gaps = 34/435 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE-AEGGAESQFEI 88
++ L+ L I D+ + + +E E +L V +L E ++ + + + EI
Sbjct: 1893 MNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1952
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI------VIDFQEQIDQLTKTKARA 142
RK E ++ + ++E LLK+K QE+ I +QE+I L +T
Sbjct: 1953 -RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKAL 2011
Query: 143 EKEKSKFQAEVY---ELLAQ-VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
E +++ Q ++ E LAQ VE+ K + ++ L+ T SE + + + ++
Sbjct: 2012 EFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL 2071
Query: 199 TSHKQ----RLSQENIELVKEVQDLKVNI----ENVVYLKSQIASQXXXXXXXXXXXXXX 250
S+K+ ++ Q++ +L + ++ + +N+ + +
Sbjct: 2072 QSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVT 2131
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
+ Q++ +L+S QL +++ L+ + E W KF
Sbjct: 2132 LNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2191
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR 370
S + N+ SRL+ + ++ KA + QK
Sbjct: 2192 IRLKEDNCSVLKDQLRQMSIHMEELKINI----SRLEHDKQIWE---SKAQTEVQLQQKV 2244
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQR-------VSHELDKTREQKDAL 423
+ L+ N E+ S+LEET LY +Q +L ++EL+ +S+ L+K +EQK L
Sbjct: 2245 CDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNL 2304
Query: 424 ARENKKMGDDLHDAR 438
++ D+ +++
Sbjct: 2305 EGIIRQQEADIQNSK 2319
Score = 42.7 bits (96), Expect = 0.003
Identities = 48/204 (23%), Positives = 87/204 (42%), Gaps = 8/204 (3%)
Query: 32 ALSRLEDKIRLIQDDLESERE-LRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+LS + ++L + L ++E L + IE K+ + + E+ +E + E +
Sbjct: 1530 SLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYE 1589
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKK---KNQEIVIDFQEQIDQLTKTKARAEKEKS 147
E +++ ++E V E +E L+ +E QE ++ + K + K
Sbjct: 1590 NVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAK 1649
Query: 148 KFQAEVYELLAQVENVTKEKITISKTC-ERLEITISELHIKIEELNRTIVD---ITSHKQ 203
Q ++ EL + + + E T E +E +S EEL R ++ ++ Q
Sbjct: 1650 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQ 1709
Query: 204 RLSQENIELVKEVQDLKVNIENVV 227
L E L +EVQDLK IE V
Sbjct: 1710 SLMSEKDSLSEEVQDLKHQIEGNV 1733
Score = 42.3 bits (95), Expect = 0.004
Identities = 82/442 (18%), Positives = 174/442 (39%), Gaps = 34/442 (7%)
Query: 26 YSADLSALSRLED--KIRLIQDDLESER-ELRQRIEREKADL---SVQVIQLSERLEEAE 79
+S D SAL +I+ ++E+E+ EL ++ ++L S +V QL E++ +
Sbjct: 1257 HSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQG 1316
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHL--LKKKN---QEIVIDFQEQIDQ 134
ES ++ + + L++ LE L+ HL L+ K Q+++ +E +
Sbjct: 1317 LEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSY 1376
Query: 135 LTKTKARAEKEKSKFQAEVYE-------LLAQVENVTKEKITISKTCERLEITISELHIK 187
L+ + E +K Q E+ E L Q+E KE + ++L++ + E+ K
Sbjct: 1377 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQK 1433
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
EE+ +++L I + +++ K E + + I
Sbjct: 1434 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1493
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGE--------IGHWRSK 299
L ++ + L+ R +L E + L LE Q + ++ E + + K
Sbjct: 1494 SAQNKEKDTVLGRLAL-LQEERDKLITEMDRSL-LENQSLSSSCESLKLALEGLTEDKEK 1551
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
++ L+ NV + R+Q VE + + ++
Sbjct: 1552 LVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQE 1611
Query: 360 ANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
G R + ++ E+ E + +EE + E+ ++ ++KQ ++ + E D+ R +
Sbjct: 1612 LYGKLRSTEANKKETEKQLQEAEQEMEE---MKEKMRKFAKSKQQKILELEEENDRLRAE 1668
Query: 420 KDALARENKKMGDDLHDARANI 441
K+ + L + A++
Sbjct: 1669 VHPAGDTAKECMETLLSSNASM 1690
Score = 42.3 bits (95), Expect = 0.004
Identities = 70/421 (16%), Positives = 161/421 (38%), Gaps = 21/421 (4%)
Query: 21 DVNIEYSADL-SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
+V ++ + +L + ++LE+K++ ++ E R ++ EK DLS ++ L + +
Sbjct: 2522 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2581
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
++ ++ L L V E L +Q+ + + +E++ + K
Sbjct: 2582 R------QVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEA 2635
Query: 140 ARAEKE-KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
A+ E + K + E+ L + E T + L + E+ K+ + + +
Sbjct: 2636 AKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGL 2695
Query: 199 TSHKQRLSQENIELV-------KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXX 251
T+ Q + L +E+ +LK + + +Q+ Q
Sbjct: 2696 TAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETA 2755
Query: 252 XXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX-- 309
++ LE + QL + E L L QL + ++ +
Sbjct: 2756 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLW 2815
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
K T A++ +++K S LQ++ + L+ +L+ ++ +
Sbjct: 2816 NELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2875
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+L + +++ ++T + ++ Q +LR + Q HELD+ R +K + ++
Sbjct: 2876 EITELHPLKAQLQEYQDKT-KAFQIMQEELRQENLSWQ---HELDQLRMEKSSWEIHERR 2931
Query: 430 M 430
M
Sbjct: 2932 M 2932
Score = 41.9 bits (94), Expect = 0.005
Identities = 76/415 (18%), Positives = 165/415 (39%), Gaps = 28/415 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LS+LE+ L S+ EL ++E E L Q+ LS LE+ + + I R++
Sbjct: 2256 LSQLEETRHLYHS---SQNELA-KLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2311
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAE 152
+ ++ + E + + + + L + ++EI + Q+ I L + KE++ Q
Sbjct: 2312 EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLL------SGKEEA-IQVA 2364
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIK-IEELNRTIVDITSHKQRLSQENIE 211
+ EL Q + KE + E I + E + K +++ N+ + + + K+ Q+ +
Sbjct: 2365 IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQ 2424
Query: 212 L---VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESV 268
L VK + L+ + + +V Q+ + A ++++ ++ +
Sbjct: 2425 LDSFVKSMSSLQNDRDRIVGDYQQLEER---HLSIILEKDQLIQEAAAENNKLKEEIRGL 2481
Query: 269 RVQLEEESEARLDLERQLVKANGEIGH-------WRSKFXXXXXXXXXXXXXXXXKYSXX 321
R +++ + L+ +L++ ++ + + K
Sbjct: 2482 RSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEK 2541
Query: 322 XXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR-TEQLERVNIE 380
L N ++++K L E+E L + + + LQ+ T L ++
Sbjct: 2542 LKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLK 2601
Query: 381 IK-SRLEETVQLYEQTQRDLRNKQTELQRVSHE-LDKTREQKDALARENKKMGDD 433
+K + L+ +Q+ + + EL V E K E +D L +E K + D
Sbjct: 2602 VKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHD 2656
Score = 40.3 bits (90), Expect = 0.016
Identities = 63/384 (16%), Positives = 142/384 (36%), Gaps = 14/384 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
LE++ + D E + I++E Q+ + + + + + + E
Sbjct: 2393 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRI--VGDYQQLE 2450
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
L +LE L E A K +E + + +D L A+ + E +++ ++ +
Sbjct: 2451 ERHLSIILEKDQLIQEAAAE--NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2508
Query: 156 LLAQVENVTKEKITIS-KTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVK 214
++ ++ K+ + + + + LE ++L K++E D+ L +E +L K
Sbjct: 2509 VITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2568
Query: 215 EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE 274
E++ LKV+I L Q+ + +H++ S + ++ E
Sbjct: 2569 EIESLKVSISQ---LTRQVTA--LQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAE 2623
Query: 275 ESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIA 334
E + ++++ K GEI K +
Sbjct: 2624 LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2683
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ V K+ L ++++ + + + ++L+R + + L+E QL EQ
Sbjct: 2684 KLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKR---KYDASLKELAQLKEQ 2740
Query: 395 TQRDLRNKQTELQRVSHELDKTRE 418
+ R + L + ++ T E
Sbjct: 2741 GLLN-RERDALLSETAFSMNSTEE 2763
Score = 38.3 bits (85), Expect = 0.064
Identities = 68/431 (15%), Positives = 173/431 (40%), Gaps = 21/431 (4%)
Query: 21 DVNIEYSADLSAL----SRLEDKIRLIQDDLESERELRQRIEREKADLS---VQVIQLSE 73
DV +++S + + S+L++K + + E R + ++E LS +++ ++ +
Sbjct: 787 DVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQ 846
Query: 74 RLEEAEGGAESQFEINRKRDTELLKLRKLLED--VHLESEETAHLLKKKNQEIVIDFQEQ 131
L E + E+ + ++D ++ ++ + + V L E+ + ++ K + ++ +
Sbjct: 847 LLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSR 906
Query: 132 IDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL 191
++ K + + E S + Y+ ++ ++KE++ + E + ++ +
Sbjct: 907 AEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALI 966
Query: 192 NRTIVDITSHKQRLSQENIELVKEVQ-DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXX 250
NR ++ RL +E L E + ++ ++ ++ ++
Sbjct: 967 NRK--ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEI 1024
Query: 251 XXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXX 310
++ + E++L+ +R LEE+ A + LVK + ++
Sbjct: 1025 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQA-LVKQMNQTLQDKTNQIDLLQAEISE 1083
Query: 311 XXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKR 370
K + K V SE ++ EK L+K
Sbjct: 1084 NQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELE-EKILA----LEKE 1138
Query: 371 TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
EQL++ +++ L + ++ Q R+ + EL++ + ++ +EQ D ++EN+ +
Sbjct: 1139 KEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1195
Query: 431 GDDLHDARANI 441
GD L + +
Sbjct: 1196 GDQLRQLQIQV 1206
Score = 38.3 bits (85), Expect = 0.064
Identities = 80/424 (18%), Positives = 164/424 (38%), Gaps = 40/424 (9%)
Query: 30 LSALSRLEDKIRLIQDDLESEREL----RQRIEREKADLSVQVIQLSERLEEAEGGAESQ 85
L +SRLE+++ ++D+ + E L R +E +K + ++ + +E E +
Sbjct: 972 LQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQT 1031
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+++ EL +RK LE+ E+ L+K+ NQ + Q++ +Q+ +A +
Sbjct: 1032 IS---EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTL----QDKTNQIDLLQAEISEN 1084
Query: 146 KSKFQAEVYELLAQVEN----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++ Q + + + KE + IS C T S H K EL I+ +
Sbjct: 1085 QAIIQKLITSNTDASDGDSVALVKETVVISPPC-----TGSSEHWK-PELEEKILALEKE 1138
Query: 202 KQRLSQENIE-LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
K++L ++ E L LK E +L+ ++ Q
Sbjct: 1139 KEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKEN----EN 1194
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXX------ 314
+ L +++Q+ E + +L Q + G F
Sbjct: 1195 IGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDW 1254
Query: 315 -XXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
+ A++ +E +K L+ +V +L K + +LQ EQ
Sbjct: 1255 PSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQ---EQ 1311
Query: 374 LERVNIEIKS--RLEETVQLY-EQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
+ + +EI+S + +++ E Q+ L + Q ++ + H L + + + D L + K
Sbjct: 1312 INKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH-LRELQPKLDELQKLISKK 1370
Query: 431 GDDL 434
+D+
Sbjct: 1371 EEDV 1374
Score = 36.7 bits (81), Expect = 0.19
Identities = 85/414 (20%), Positives = 166/414 (40%), Gaps = 35/414 (8%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLE-EAEGGAESQFEINRKRDTE 95
E +++ + ++E +E ++ + K +++ + ++RL E ++ E +
Sbjct: 1627 EKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSS 1686
Query: 96 LLKLRKLLEDVHLE----SEETAHLLKKKNQ--EIVIDFQEQIDQLTKTKARAEK-EKSK 148
+++ LE V +E S++ L+ +K+ E V D + QI+ +A E EK
Sbjct: 1687 NASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1746
Query: 149 FQAEVYELLAQ-VENVTKEKITISK----TCERLEITISELHIKIEELNRTIVDITSHKQ 203
Q V E Q + T+E+ ++S TC + + + + + +I ++ Q
Sbjct: 1747 NQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ 1806
Query: 204 RLSQ--ENIE-LVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
++ Q E I L +E Q K + + K+ + SQ Q
Sbjct: 1807 QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQ 1866
Query: 261 VEIDLESVRVQLEEESEARLDLER----QLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
++ +L V E E + DLE QL + NG IG++
Sbjct: 1867 IQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNEL------- 1919
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
L + + K+K++++SE+ LEK G +E ++ E
Sbjct: 1920 -LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY--LEKIQGAQKEPGNKSHAKEL 1976
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELD--KTREQKD-ALAREN 427
+ +K + +E QL + R + K + L+R L+ +T QKD + +EN
Sbjct: 1977 QEL-LKEKQQEVKQLQKDCIR-YQEKISALERTVKALEFVQTESQKDLEITKEN 2028
Score = 31.9 bits (69), Expect = 5.5
Identities = 38/200 (19%), Positives = 87/200 (43%), Gaps = 8/200 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A+ RL+ + + D+L +E+ IE + D+ ++V+Q L++ + Q
Sbjct: 740 AEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQ--NELDDVQLQFSEQST 797
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ R ++L + E LE E + K +E+ ++ ++TK ++K
Sbjct: 798 LIRSLQSQL----QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKR 853
Query: 148 KFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
+ + + + VT+ ++++ +L L ++I+ L + ++ S + +
Sbjct: 854 DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQL-NLLSRAEEAKK 912
Query: 208 ENIELVKEVQD-LKVNIENV 226
E +E EV LK N + +
Sbjct: 913 EQVEEDNEVSSGLKQNYDEM 932
>BC133019-1|AAI33020.1| 1427|Homo sapiens LOC650001 protein protein.
Length = 1427
Score = 48.8 bits (111), Expect = 5e-05
Identities = 83/442 (18%), Positives = 186/442 (42%), Gaps = 53/442 (11%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
L ++E+ + ++Q++L ++ + ++E +K + ++ L L++ E + ++ +
Sbjct: 663 LKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQ-ENEEKRNADMLYNK 721
Query: 93 DTELLKLR-----KLLEDVHLESEETAHLLK-----KKNQEIVI----DFQEQIDQLTKT 138
D+E L+++ K++E L+K + N ++V+ D Q+Q+ +
Sbjct: 722 DSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDA 781
Query: 139 KARAEKEKSKFQAEVYELLAQVENVT-----KEKITISKTCERLEITISELHIKIEELNR 193
+ ++ + Q E+ ++ + KEK + C L+ I+ L ++I+
Sbjct: 782 RILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDC-MLQEEIALLRLEID---- 836
Query: 194 TIVDITSHKQRLSQENIELVKEVQD-----LKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
TI + K++ E+IE VKE D +K+N E + Q + Q
Sbjct: 837 TIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILN 896
Query: 249 XXXXXXXASLHQVEIDLESVRVQLE------EESEARLDLERQLVKANGEIGHWRSKFXX 302
+ ++EI++ES R +L ++S+ DL+ + E K
Sbjct: 897 SELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKV 956
Query: 303 XXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEV--EVLIIDLEKA 360
K S +KIN+++ Q + + E LI++ +
Sbjct: 957 DMSGLQAKNEILSEKLSNAE-----------SKINSLQIQLHNTRDALGRESLILERVQR 1005
Query: 361 NGTARELQKR-TEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+ + + QK+ TEQ+ ++ +S+L++ + E + L Q+E + +LD ++
Sbjct: 1006 DLSQTQCQKKETEQMYQIE---QSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKK 1062
Query: 420 KDALARENKKMGDDLHDARANI 441
++ + + + D H A N+
Sbjct: 1063 ANSQEKTSSTIQDQFHSAAKNL 1084
Score = 36.3 bits (80), Expect = 0.26
Identities = 43/175 (24%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 53 LRQRIEREKADLSVQVIQLSERLEEAEGGAES-QFEINRKRDTELLKLRKLLEDVHLESE 111
L +++ + + L + LSE+L AE S Q +++ RD L + +LE V +
Sbjct: 950 LHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDA-LGRESLILERVQRDLS 1008
Query: 112 ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITIS 171
+T K+ Q I+ Q ++ + + E+ S+ Q+E L Q+++ K+ +
Sbjct: 1009 QTQCQKKETEQMYQIE-QSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQE 1067
Query: 172 KTCERLEITISELHIKIEELNRTIVDITSHKQRLS--QENIELVKEVQDLKVNIE 224
KT ++ + H + L S KQ LS ++N EL+ E LK ++
Sbjct: 1068 KTSSTIQ---DQFHSAAKNL-----QAESEKQILSLQEKNKELMDEYNHLKERMD 1114
Score = 31.5 bits (68), Expect = 7.3
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query: 333 IAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQ-L 391
IAK +VE++ S+LQSE +L L+ A+ K+ E+ + I+ + + L
Sbjct: 1032 IAKQESVEERLSQLQSENMLLRQQLDDAH-------KKANSQEKTSSTIQDQFHSAAKNL 1084
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
++++ + + Q + + + E + +E+ D +E DL +A+ +
Sbjct: 1085 QAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETV 1134
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.8 bits (111), Expect = 5e-05
Identities = 76/418 (18%), Positives = 165/418 (39%), Gaps = 34/418 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE--AEGGA----ESQ 85
+L+ E + ++Q ++++ LR R+E ++ L+ + Q+ + EE + G +
Sbjct: 509 SLTAKEQRAAILQTEVDA---LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
++ ++ L K + L++ + E+ LK++ + + D LT T A E
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT-TLEEALAE 624
Query: 146 KSKFQAEVYELLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + + E + E +E+I K + L+ +S L + E +++D+ H
Sbjct: 625 KERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 205 LSQENIELVKEVQDLKVNIEN----VVYLKSQI-----------ASQXXXXXXXXXXXXX 249
L+ ++ ++ L++ +E + ++SQ+ AS
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 250 XXXXXXASLHQVEID-----LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXX 304
+S Q E+D L+ V + ++ + +LERQ+ N ++ + + K
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEK 804
Query: 305 XXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKAN 361
+ +L K + +E+ + L+ V++ + L +
Sbjct: 805 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 864
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+K+ E+L ++K LE TQ+ L K+T L + E K E+
Sbjct: 865 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 922
Score = 44.0 bits (99), Expect = 0.001
Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREK-----------ADLSVQVIQLSERLEEAE 79
+AL+ LE+ + + +E +E R R EREK DL +V L L E E
Sbjct: 613 TALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 672
Query: 80 GG-------AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----ID 127
A S K+D+ L L LE E + LKK ++ + +
Sbjct: 673 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 732
Query: 128 FQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK 187
++I L + R + E SK QAEV LL ++ V EK K I+EL +
Sbjct: 733 MSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK-------KIAELERQ 785
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+++ N+ + ++ +Q +++ ++++E + + N+ +
Sbjct: 786 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 823
Score = 42.7 bits (96), Expect = 0.003
Identities = 70/406 (17%), Positives = 145/406 (35%), Gaps = 15/406 (3%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E QR+ E + ++ L + LEE E E+Q + RD + KL ++L+
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
L ++ T ++ + + + + + L + EKE S + E++ + K K
Sbjct: 321 LSAKATEEDHERTRR--LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTK 378
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ E + IS + + +L I + S+ ++E E +K+++ + + + +
Sbjct: 379 -ALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK 437
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Q+ + A + QV+ +L +L L Q
Sbjct: 438 NKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
+ I + +I ++ ++K
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDA-LRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E+ L L+ LQK+ E L+ + + ++ + + Q D N T L
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 408 RVSHEL-------DKTREQKDALARENKKMGD----DLHDARANIT 442
+ L ++ +EQ+D RE ++ D DL D + ++
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 662
Score = 42.3 bits (95), Expect = 0.004
Identities = 75/409 (18%), Positives = 163/409 (39%), Gaps = 27/409 (6%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ +QD+L +R+L Q +++ + + + ++E EE ++ E K EL L
Sbjct: 229 IQALQDELRIQRDLNQLFQQDSSSRTGEPC-VAELTEENFQRLHAEHERQAK---ELFLL 284
Query: 100 RKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTK-TKARAEKEKSKFQAE--VY 154
RK LE++ L E L +++ I +++ + K T+ E+ + +AE V+
Sbjct: 285 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVH 344
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI-ELV 213
L + +E KE + + R + K + L +T++++ K + + +L
Sbjct: 345 HLESLLEQKEKENSMLREEMHR-RFENAPDSAKTKAL-QTVIEMKDSKISSMERGLRDLE 402
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+E+Q LK N + + Q + Q++ +L S Q E
Sbjct: 403 EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKN-------KVEQLKEELSSKEAQWE 455
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
E + L+ ++ G++ S+ ++S +L
Sbjct: 456 ELKKKAAGLQAEI----GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK E++ + LQ+EV+ L + LE+ + K+ + + + + + +
Sbjct: 512 AK----EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLD 567
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+R + Q +++ + +L +Q +L K + D + +T
Sbjct: 568 VKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Score = 37.5 bits (83), Expect = 0.11
Identities = 62/368 (16%), Positives = 141/368 (38%), Gaps = 15/368 (4%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E+ +R E + +Q +++++ + + + + + ++LK L E E
Sbjct: 363 EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEE 422
Query: 112 ETAHLLKKKNQEIVIDFQEQI-DQLTKTKARAEKEKSK---FQAEVYELLAQVENVTKEK 167
+ + + + + + EQ+ ++L+ +A+ E+ K K QAE+ ++ ++ E
Sbjct: 423 MKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTEL 482
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ + E L S+ IE L + +T+ +QR + L EV L++ +E
Sbjct: 483 LALQTKLETLTNQFSDSKQHIEVLKES---LTAKEQRAA----ILQTEVDALRLRLEEKE 535
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+ ++ Q L E + ++ ++E E D E+Q+
Sbjct: 536 TMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS 595
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK---INNVEKQKS 344
+ ++ K K I+N +K
Sbjct: 596 SLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLK 655
Query: 345 RLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQT 404
L+ +V +L DL + + +L++ L ++ SRL+ EQ + + ++
Sbjct: 656 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Query: 405 ELQRVSHE 412
+L++ +HE
Sbjct: 716 QLKK-AHE 722
Score = 34.7 bits (76), Expect = 0.79
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 16/193 (8%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLS--VQVIQLSERLEEAEGGAE-SQFEINRKRDTE 95
K + +Q +E + +ER DL +Q+++ + L E E Q E+ R
Sbjct: 376 KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKF 435
Query: 96 LL-KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ K+ +L E++ + + L KK Q +I Q+ + +R + E Q ++
Sbjct: 436 MKNKVEQLKEELSSKEAQWEELKKK-----AAGLQAEIGQVKQELSRKDTELLALQTKLE 490
Query: 155 ELLAQVEN------VTKEKITISKT-CERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
L Q + V KE +T + L+ + L +++EE + T Q +++
Sbjct: 491 TLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE 550
Query: 208 ENIELVKEVQDLK 220
E E+ DLK
Sbjct: 551 EKGTQAGEIHDLK 563
Score = 33.5 bits (73), Expect = 1.8
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 13/192 (6%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E S + + RL + ++ ++++ + + +ER+ D + +V L + + + +
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 809
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-IDFQEQIDQLTKTKARAE 143
E R+R+ L + L+D + ++ L++ +E V I + ++ + AR
Sbjct: 810 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 869
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
EK +V ELL +E V +E E ++ +S + E + ++ + ++
Sbjct: 870 AEK-----QVEELLMAMEKVKQE-------LESMKAKLSSTQQSLAEKETHLTNLRAERR 917
Query: 204 RLSQENIELVKE 215
+ +E +E+ +E
Sbjct: 918 KHLEEVLEMKQE 929
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.8 bits (111), Expect = 5e-05
Identities = 76/418 (18%), Positives = 165/418 (39%), Gaps = 34/418 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE--AEGGA----ESQ 85
+L+ E + ++Q ++++ LR R+E ++ L+ + Q+ + EE + G +
Sbjct: 509 SLTAKEQRAAILQTEVDA---LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
++ ++ L K + L++ + E+ LK++ + + D LT T A E
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT-TLEEALAE 624
Query: 146 KSKFQAEVYELLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + + E + E +E+I K + L+ +S L + E +++D+ H
Sbjct: 625 KERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 205 LSQENIELVKEVQDLKVNIEN----VVYLKSQI-----------ASQXXXXXXXXXXXXX 249
L+ ++ ++ L++ +E + ++SQ+ AS
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 250 XXXXXXASLHQVEID-----LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXX 304
+S Q E+D L+ V + ++ + +LERQ+ N ++ + + K
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEK 804
Query: 305 XXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKAN 361
+ +L K + +E+ + L+ V++ + L +
Sbjct: 805 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 864
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+K+ E+L ++K LE TQ+ L K+T L + E K E+
Sbjct: 865 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 922
Score = 44.0 bits (99), Expect = 0.001
Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREK-----------ADLSVQVIQLSERLEEAE 79
+AL+ LE+ + + +E +E R R EREK DL +V L L E E
Sbjct: 613 TALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 672
Query: 80 GG-------AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----ID 127
A S K+D+ L L LE E + LKK ++ + +
Sbjct: 673 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 732
Query: 128 FQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK 187
++I L + R + E SK QAEV LL ++ V EK K I+EL +
Sbjct: 733 MSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK-------KIAELERQ 785
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+++ N+ + ++ +Q +++ ++++E + + N+ +
Sbjct: 786 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 823
Score = 42.7 bits (96), Expect = 0.003
Identities = 70/406 (17%), Positives = 145/406 (35%), Gaps = 15/406 (3%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E QR+ E + ++ L + LEE E E+Q + RD + KL ++L+
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
L ++ T ++ + + + + + L + EKE S + E++ + K K
Sbjct: 321 LSAKATEEDHERTRR--LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTK 378
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ E + IS + + +L I + S+ ++E E +K+++ + + + +
Sbjct: 379 -ALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK 437
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Q+ + A + QV+ +L +L L Q
Sbjct: 438 NKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
+ I + +I ++ ++K
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDA-LRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E+ L L+ LQK+ E L+ + + ++ + + Q D N T L
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 408 RVSHEL-------DKTREQKDALARENKKMGD----DLHDARANIT 442
+ L ++ +EQ+D RE ++ D DL D + ++
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 662
Score = 42.3 bits (95), Expect = 0.004
Identities = 75/409 (18%), Positives = 163/409 (39%), Gaps = 27/409 (6%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ +QD+L +R+L Q +++ + + + ++E EE ++ E K EL L
Sbjct: 229 IQALQDELRIQRDLNQLFQQDSSSRTGEPC-VAELTEENFQRLHAEHERQAK---ELFLL 284
Query: 100 RKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTK-TKARAEKEKSKFQAE--VY 154
RK LE++ L E L +++ I +++ + K T+ E+ + +AE V+
Sbjct: 285 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVH 344
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI-ELV 213
L + +E KE + + R + K + L +T++++ K + + +L
Sbjct: 345 HLESLLEQKEKENSMLREEMHR-RFENAPDSAKTKAL-QTVIEMKDSKISSMERGLRDLE 402
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+E+Q LK N + + Q + Q++ +L S Q E
Sbjct: 403 EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKN-------KVEQLKEELSSKEAQWE 455
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
E + L+ ++ G++ S+ ++S +L
Sbjct: 456 ELKKKAAGLQAEI----GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK E++ + LQ+EV+ L + LE+ + K+ + + + + + +
Sbjct: 512 AK----EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLD 567
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+R + Q +++ + +L +Q +L K + D + +T
Sbjct: 568 VKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Score = 37.5 bits (83), Expect = 0.11
Identities = 62/368 (16%), Positives = 141/368 (38%), Gaps = 15/368 (4%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E+ +R E + +Q +++++ + + + + + ++LK L E E
Sbjct: 363 EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEE 422
Query: 112 ETAHLLKKKNQEIVIDFQEQI-DQLTKTKARAEKEKSK---FQAEVYELLAQVENVTKEK 167
+ + + + + + EQ+ ++L+ +A+ E+ K K QAE+ ++ ++ E
Sbjct: 423 MKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTEL 482
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ + E L S+ IE L + +T+ +QR + L EV L++ +E
Sbjct: 483 LALQTKLETLTNQFSDSKQHIEVLKES---LTAKEQRAA----ILQTEVDALRLRLEEKE 535
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+ ++ Q L E + ++ ++E E D E+Q+
Sbjct: 536 TMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS 595
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK---INNVEKQKS 344
+ ++ K K I+N +K
Sbjct: 596 SLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLK 655
Query: 345 RLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQT 404
L+ +V +L DL + + +L++ L ++ SRL+ EQ + + ++
Sbjct: 656 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Query: 405 ELQRVSHE 412
+L++ +HE
Sbjct: 716 QLKK-AHE 722
Score = 34.7 bits (76), Expect = 0.79
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 16/193 (8%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLS--VQVIQLSERLEEAEGGAE-SQFEINRKRDTE 95
K + +Q +E + +ER DL +Q+++ + L E E Q E+ R
Sbjct: 376 KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKF 435
Query: 96 LL-KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ K+ +L E++ + + L KK Q +I Q+ + +R + E Q ++
Sbjct: 436 MKNKVEQLKEELSSKEAQWEELKKK-----AAGLQAEIGQVKQELSRKDTELLALQTKLE 490
Query: 155 ELLAQVEN------VTKEKITISKT-CERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
L Q + V KE +T + L+ + L +++EE + T Q +++
Sbjct: 491 TLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE 550
Query: 208 ENIELVKEVQDLK 220
E E+ DLK
Sbjct: 551 EKGTQAGEIHDLK 563
Score = 33.5 bits (73), Expect = 1.8
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 13/192 (6%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E S + + RL + ++ ++++ + + +ER+ D + +V L + + + +
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 809
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-IDFQEQIDQLTKTKARAE 143
E R+R+ L + L+D + ++ L++ +E V I + ++ + AR
Sbjct: 810 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 869
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
EK +V ELL +E V +E E ++ +S + E + ++ + ++
Sbjct: 870 AEK-----QVEELLMAMEKVKQE-------LESMKAKLSSTQQSLAEKETHLTNLRAERR 917
Query: 204 RLSQENIELVKE 215
+ +E +E+ +E
Sbjct: 918 KHLEEVLEMKQE 929
>BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein.
Length = 954
Score = 48.8 bits (111), Expect = 5e-05
Identities = 86/407 (21%), Positives = 171/407 (42%), Gaps = 54/407 (13%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
LS LE + ++ +L RE ++ E + +L Q++ + L EA + + +
Sbjct: 160 LSDLESTVSQLRSEL---REAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNL 216
Query: 93 DTELLKL----RKLLEDVHLESEETAHLLKKKN-QEIVID-FQEQID----QLTKTKARA 142
D +L KL K +++ LE E+ L + I ID + ++D ++ + +A
Sbjct: 217 DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALL 276
Query: 143 EKEKSKFQAEVYELLAQVE--NVTKEKIT-----ISKTCERLEITISELHIK---IEELN 192
+ KS+ Q ++ +A ++ N + EK++ + T E L + EL K +E
Sbjct: 277 KALKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSE 336
Query: 193 RTIVDITS---HKQR-LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXX 248
RTI D+T+ K+R + N E+ K + + ++ + +LK++
Sbjct: 337 RTISDLTTSLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNE---------------- 380
Query: 249 XXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIG-HWRSKFXXXXXXX 307
L V+ + E++++Q+ E+ + L +Q+ +G H R+
Sbjct: 381 ------GDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 434
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSE-VEVLIIDLEKANGTARE 366
+ AKI +E + S L+ E V+++ E+
Sbjct: 435 QLEKEINDRRMELKELKILKDKKD--AKIRELEARVSDLELEKVKLVNAGSERLRAVKDI 492
Query: 367 LQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
Q+R + L V +S L + YE +R+ RNK E++ +++L
Sbjct: 493 KQERDQLLNEVKTS-RSELNNLSEEYEVLKRNFRNKSEEMEMTTNKL 538
Score = 41.5 bits (93), Expect = 0.007
Identities = 25/110 (22%), Positives = 54/110 (49%), Gaps = 6/110 (5%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L K ++ Q + +QS++E++ E+A ++ LE +++S L E ++
Sbjct: 124 LTEKASSARSQANSIQSQMEII---QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRM 180
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
YE +L + +L + EL + R ++D ++E+ + D L A++
Sbjct: 181 YEDKTEEL---EKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADL 227
Score = 38.7 bits (86), Expect = 0.048
Identities = 32/183 (17%), Positives = 79/183 (43%), Gaps = 4/183 (2%)
Query: 13 RSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLS 72
++ G +V E A ++ + I +++ +E+ +L + R + V+ QL
Sbjct: 378 KNEGDHLRNVQTECEALKLQMTEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLE 437
Query: 73 ERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQI 132
+ + + + + K+D ++ +L + D+ LE + + + V D +++
Sbjct: 438 KEINDRRMELKELKILKDKKDAKIRELEARVSDLELEKVKLVN-AGSERLRAVKDIKQER 496
Query: 133 DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN 192
DQL + E + +E YE+L + N + + T +L++ + ++E+
Sbjct: 497 DQLLNEVKTSRSELNNL-SEEYEVLKR--NFRNKSEEMEMTTNKLKMQLKSAQSELEQTR 553
Query: 193 RTI 195
T+
Sbjct: 554 NTL 556
Score = 37.1 bits (82), Expect = 0.15
Identities = 86/479 (17%), Positives = 188/479 (39%), Gaps = 59/479 (12%)
Query: 12 YRSSGGGTTDVNIEYSADLSALSR----LEDKIRLIQDDLESEREL-----RQRIEREKA 62
+RS G + + E ++S L +ED++ ++ + +++ EL + RIE+ +
Sbjct: 56 FRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLIS 115
Query: 63 DLSVQVIQLSERLEEAEGGA---ESQFEI--NRKRDTELLKLRKL--LEDV--HLESE-- 111
+ V++ L+E+ A A +SQ EI + R+ + +R+L LE L SE
Sbjct: 116 EHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELR 175
Query: 112 ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK---EKSKFQAEVYELLAQVENVTKEKI 168
E + + K +E+ +LT+ + ++ E ++ +LLA + KE
Sbjct: 176 EAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 235
Query: 169 TISKTCERL-------EITISELHIKIEELNRTIVDITSHKQRLSQE------------- 208
+ +RL ITI L +++ N + + + + L E
Sbjct: 236 LEKEQNKRLWDRDTGNSITIDHLRRELDNRNMEVQRLEALLKALKSECQGQMERQMAAIQ 295
Query: 209 -NIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLES 267
E +++V L +E+ + ++ + SL + E +E+
Sbjct: 296 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTISDLTTSLQEKERAIEA 355
Query: 268 VRVQLEEESEARLDLERQ-LVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXX 326
++ + +R+DL+ Q L E H R+ K
Sbjct: 356 TNAEITK-LRSRVDLKLQELQHLKNEGDHLRN--VQTECEALKLQMTEKDKVIEILRQQI 412
Query: 327 XXXXTLIAKINN----VEKQKSRLQSEVEVLIIDL-------EKANGTARELQKRTEQLE 375
L+ + ++ +K++L+ E+ ++L +K + REL+ R LE
Sbjct: 413 ENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRMELKELKILKDKKDAKIRELEARVSDLE 472
Query: 376 RVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+++ + E ++ + +++ E++ EL+ E+ + L R + +++
Sbjct: 473 LEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEM 531
>BC017293-1|AAH17293.1| 577|Homo sapiens moesin protein.
Length = 577
Score = 48.8 bits (111), Expect = 5e-05
Identities = 36/169 (21%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 57 IEREKAD-LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
+ R K D + VQ ++ R E+ + E N K+ E+ + K E + E EE
Sbjct: 292 MRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK--EKIEREKEELME 349
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LK+ ++ Q+++++ T+ E+E+ + Q+E +L + + + K + +
Sbjct: 350 RLKQIEEQTK-KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASR 408
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ T +L +++ EL I + +Q+ E +E ++ Q ++ ++E
Sbjct: 409 DQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLE 457
Score = 39.5 bits (88), Expect = 0.028
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
A + N +K++ + E E I+ EK EL +R +Q+E + + LEE +
Sbjct: 321 AMLENEKKKREMAEKEKEK--IEREK-----EELMERLKQIEEQTKKAQQELEEQTRRAL 373
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDAL---ARENKKMGDDLHDARANIT 442
+ +++ + Q+E ++++ E + E K+AL +R+ KK + L A +T
Sbjct: 374 ELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELT 425
Score = 38.7 bits (86), Expect = 0.048
Identities = 32/124 (25%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERL---EEAEGGAESQFEINRKRDTELLKLRKLL 103
LE+E++ R+ E+EK + + +L ERL EE A+ + E +R EL + RK
Sbjct: 323 LENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERK-- 380
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
++ A L K+ QE + +E + Q ++ + + +++ + AE+ ++Q+E
Sbjct: 381 -----RAQSEAEKLAKERQE-AEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMA 434
Query: 164 TKEK 167
++K
Sbjct: 435 RQKK 438
Score = 35.9 bits (79), Expect = 0.34
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 3/128 (2%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
+ L ++E++ + Q +LE + +E+E+ + +L++ +EAE E+ + +
Sbjct: 348 MERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQAS 407
Query: 90 R--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
R K+ E L L + E A KK+++ + + Q+ Q K RAE + +
Sbjct: 408 RDQKKTQEQLALEMAELTARISQLEMAR-QKKESEAVEWQQKAQMVQEDLEKTRAELKTA 466
Query: 148 KFQAEVYE 155
V E
Sbjct: 467 MSTPHVAE 474
Score = 33.1 bits (72), Expect = 2.4
Identities = 24/137 (17%), Positives = 51/137 (37%)
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
K + AEKEK K + E EL+ +++ + ++ + E EL + +
Sbjct: 328 KKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAE 387
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
+ +Q + L++ +D K E + +++ ++
Sbjct: 388 KLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQ 447
Query: 257 SLHQVEIDLESVRVQLE 273
V+ DLE R +L+
Sbjct: 448 KAQMVQEDLEKTRAELK 464
Score = 32.3 bits (70), Expect = 4.2
Identities = 27/118 (22%), Positives = 59/118 (50%), Gaps = 9/118 (7%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAR-ELQKRTEQLERVNIEIKSRLEE 387
L+ ++ +E+Q + Q E+E ++LE+ A+ E +K ++ + E K L +
Sbjct: 347 LMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAE-EAKEALLQ 405
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALA----RENKKMGDDLHDARANI 441
+ ++TQ L + EL +L+ R++K++ A ++ + + +DL RA +
Sbjct: 406 ASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAEL 463
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 48.8 bits (111), Expect = 5e-05
Identities = 84/411 (20%), Positives = 157/411 (38%), Gaps = 22/411 (5%)
Query: 30 LSALSRLEDKI----RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA-EGGAES 84
L+ +LE+KI + + E E+EL ++ E+ ++ L + E++ A E +
Sbjct: 327 LTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRS-LETNINTEHEKICLAFEKAKKI 385
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEK 144
E +++ + ++ +L LE + +E + Q+I+ Q ++ L + ++
Sbjct: 386 HLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICK-QHHLESLDRLLTESKG 444
Query: 145 EKSKFQAEVYELLAQVEN-VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
E K + E L ++N V++E I + + LEI EL + + +L +
Sbjct: 445 EMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLK 504
Query: 204 RLSQENIELVKEVQ----DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
+ S+E L KE++ L+ E V L+ + Q
Sbjct: 505 KKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEK 564
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
QV + ++ Q E +E +E + A E R K +Y
Sbjct: 565 QVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMD-QYK 623
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNI 379
L N S+L ++ +LEK +EL+K E
Sbjct: 624 EELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTE---- 679
Query: 380 EIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTRE--QKDALARENK 428
+ L E +Q E + +L+N EL+ +L + R+ QK L+ E K
Sbjct: 680 ---TELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEK 727
Score = 46.8 bits (106), Expect = 2e-04
Identities = 85/425 (20%), Positives = 178/425 (41%), Gaps = 29/425 (6%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S L L++K+R ++++ + +E + + + +++ Q+ + + + + E E++ EI R
Sbjct: 41 SELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILR 100
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ + + + R+L V ++E L QEI + ++ L K ++ ++ F
Sbjct: 101 DKFSLMNENRELKVRVAAQNER----LDLCQQEIESS-RVELRSLEKIISQLPLKRELFG 155
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKI----EELNRTIVDITSHK--QR 204
+ Y Q+ + + ++ CE ++ ISEL IK+ E+ + ++T+++ Q
Sbjct: 156 FKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQS 215
Query: 205 L-----SQENIELVK-EVQDLKVNIENVV-YLKSQIA-SQXXXXXXXXXXXXXXXXXXXA 256
L SQE+ +L E + +K+ V +K Q +
Sbjct: 216 LITCNDSQESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRT 275
Query: 257 SLHQVEIDLESVRVQL-EEESEARLDLERQLVKA--NGEIGHWRSKFXXXXXXXXXXXXX 313
L Q+E + ++V + S+ +L E L KA + ++ +K
Sbjct: 276 KLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEE 335
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTE- 372
YS L+ K + ++ + +E E + + EKA E K E
Sbjct: 336 KIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEK 395
Query: 373 QLERVNIEIKSR---LEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
Q+ER+ +++ + +E + Q+D+ KQ L+ + L E K + +EN K
Sbjct: 396 QIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLL---TESKGEMKKENMK 452
Query: 430 MGDDL 434
+ L
Sbjct: 453 KDEAL 457
Score = 43.2 bits (97), Expect = 0.002
Identities = 82/426 (19%), Positives = 177/426 (41%), Gaps = 43/426 (10%)
Query: 41 RLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLR 100
+L+ +L + +++ E +K ++ QLS+ L ES + + + L
Sbjct: 183 KLVISELRIKLAIKEA-EIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGH 241
Query: 101 KLLEDVHLESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARAEKEK-------SKFQAE 152
++ E V +++ T + +K+ Q +V +E +L + +A K S+FQ
Sbjct: 242 QVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI 301
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
ELL + N +K + ++K C +L +T+ + ++EE I + L QE +E
Sbjct: 302 QEELLEKASNSSKLESEMTKKCSQL-LTLEK---QLEEKIVAYSSIAAKNAELEQELMEK 357
Query: 213 VKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQL 272
++++ L+ NI N + K +A + + ++E LE Q
Sbjct: 358 NEKIRSLETNI-NTEHEKICLAFE-----KAKKIHLEQHKEMEKQIERLEAQLEKKDQQF 411
Query: 273 EEESEARL--------------DLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKY 318
+E+ + L+R L ++ GE+ K K
Sbjct: 412 KEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKV 471
Query: 319 SXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV- 377
L+ +N +E K + + +++ E+ +EL+ + L+
Sbjct: 472 RQLDSALEICKEELVLHLNQLEGNKEKFEKQLKK---KSEEVYCLQKELKIKNHSLQETS 528
Query: 378 --NIEIKSRLEETVQLYEQ-TQR--DLRNKQTELQRVSHELD-KTREQKDALARENKKMG 431
N+ ++ L++ Q+ +Q T R +L + QT+L++ +L+ + ++Q+++ A + +KM
Sbjct: 529 EQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKME 588
Query: 432 DDLHDA 437
+ A
Sbjct: 589 EKCESA 594
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/270 (18%), Positives = 117/270 (43%), Gaps = 20/270 (7%)
Query: 34 SRLEDKIRLIQDDLESEREL---RQRIEREKADLSVQVIQLS-ERLEEAEGGAES-QFEI 88
++LE ++ ++ +L+ +RE + R EK + + L +++ E G A + E+
Sbjct: 560 TKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEM 619
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID-FQEQIDQLTKTKARAEKEKS 147
++ ++ EL K+ K E +HL+ + + ++++D + ++++ T EK +
Sbjct: 620 DQYKE-ELSKMEK--EIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH 676
Query: 148 KFQAEVYELL-------AQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITS 200
+ E+ E L +++N E + + + L + + + +EE TI D+T+
Sbjct: 677 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 736
Query: 201 H----KQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
K + + EL++ Q LK + +Q+
Sbjct: 737 ELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG 796
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQL 286
+L + E++L+ Q+E ++ + + QL
Sbjct: 797 TLEKSELELKECNKQIESLNDKLQNAKEQL 826
Score = 34.3 bits (75), Expect = 1.0
Identities = 44/220 (20%), Positives = 96/220 (43%), Gaps = 28/220 (12%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG--GAESQFEINR 90
+ L DK++ ++ L + + + E+E + L ++ + +R++E E + Q+ +
Sbjct: 812 IESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQ 871
Query: 91 KRDT-----ELLKLRKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTK------ 137
++ EL R+ +++ H E E H + +EI + E + QL+K
Sbjct: 872 YKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHG 931
Query: 138 ---------TKARAEKEKSKFQAEVYELLAQVENVTK----EKITISKTCERLEITISEL 184
+K R +++ QAE+ +L A+VE++ + E I+ + + +I+
Sbjct: 932 NHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQ 991
Query: 185 HIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+++LN + + L ++VQD IE
Sbjct: 992 KSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIE 1031
>AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein.
Length = 1498
Score = 48.8 bits (111), Expect = 5e-05
Identities = 47/211 (22%), Positives = 98/211 (46%), Gaps = 16/211 (7%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQR----IEREKADLSVQVIQLSERLEEAEGGAESQ 85
L AL D+++ +L+ E R+ ++ EK L + EE + GA +
Sbjct: 740 LDALQTRYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGAR-R 798
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHL------LKKKNQEIVIDFQEQ---IDQLT 136
E + +E L+ KL E++ ++S + HL LKK+ Q+I F +Q ++
Sbjct: 799 LEEGTEETSETLE--KLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYR 856
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIV 196
+ ++ S+ +A L ++++ + +E + + E +S LH ++ ++ + +
Sbjct: 857 RDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMA 916
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVV 227
D+ H Q +E E+ +Q L+ + E +V
Sbjct: 917 DLEGHLQSAQKERDEVETHLQSLQFDKEQMV 947
Score = 46.4 bits (105), Expect = 2e-04
Identities = 43/189 (22%), Positives = 81/189 (42%), Gaps = 8/189 (4%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A + +E+ ++ ++ E ERE QR+ A L Q+ Q+ L + + Q E ++
Sbjct: 662 AKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQ----RDQQLEALQQ 717
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+L+K L ++ E++ L+ + E+ Q ++ +L A E Q
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTRYDEL----QARLGELQGEAASREDTICLLQN 773
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
E L A ++ K + + RLE E +E+L + + + L QE
Sbjct: 774 EKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAA 833
Query: 212 LVKEVQDLK 220
L K++Q +K
Sbjct: 834 LKKQMQKIK 842
Score = 44.8 bits (101), Expect = 7e-04
Identities = 61/334 (18%), Positives = 124/334 (37%), Gaps = 15/334 (4%)
Query: 110 SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKIT 169
+EET+ L+K +E+ I Q++ L + A +K+ K + + + VE ++ +
Sbjct: 803 TEETSETLEKLREELAIK-SGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATS 861
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYL 229
+ L+ T L +++EL + ++ + K+ E L +EV ++ +++ L
Sbjct: 862 KDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVR---QHMADL 918
Query: 230 KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE-ESEARLDLERQLVK 288
+ + S + E + E+++ Q+EE + EAR + Q K
Sbjct: 919 EGHLQSAQKERDEVETHLQSLQFDKEQMVAVTEAN-EALKKQIEELQQEARKAITEQKQK 977
Query: 289 ANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQS 348
+G + S A++ + Q S
Sbjct: 978 MR-RLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAREAADAELGQLRAQGGSSDS 1036
Query: 349 EVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQR 408
+ + E+ ELQ + ++ L+E + L Q + R K EL+
Sbjct: 1037 SLALH----ERIQALEAELQA----VSHSKTLLEKELQEVIALTSQELEESREKVLELED 1088
Query: 409 VSHELDKTREQKDALARENKKMGDDLHDARANIT 442
E R++ L NKK+ +L + +T
Sbjct: 1089 ELQESRGFRKKIKRLEESNKKLALELEHEKGKLT 1122
Score = 40.7 bits (91), Expect = 0.012
Identities = 56/245 (22%), Positives = 114/245 (46%), Gaps = 31/245 (12%)
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLES-EETAHLLKKKNQE 123
S++ + + E + G E E+ +RD+ + LE E+ EE +LK+K +
Sbjct: 360 SIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS--LESSAAETQEEMLQVLKEKMR- 416
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSKFQAEV----YELLAQVE----------NVTKEKIT 169
+ Q++ L+ ++A KEK++ QA++ +L AQVE +++ E T
Sbjct: 417 ----LEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDT 472
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK---VNIENV 226
+ ++C LE +++L +E N ++ + Q ++ L+ +V+D++ ++ +N
Sbjct: 473 LKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNT 532
Query: 227 VY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR----VQLEEESEARLD 281
V+ L+ Q+ + AS ++ L+SVR QL EAR+
Sbjct: 533 VHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEIS-SLQSVRQWYQQQLALAQEARVR 591
Query: 282 LERQL 286
L+ ++
Sbjct: 592 LQGEM 596
Score = 33.5 bits (73), Expect = 1.8
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 134 QLTKTKARAEKEKSKFQAEVYELLAQV--ENVTKEKITISKTC--ERLEITISELHIKIE 189
QLT+T+ R+ KEK + A++ + A + + +I +KT E L+ + E + E
Sbjct: 623 QLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERE 682
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
L R S +Q+L Q + L++ Q L+ + + L Q+
Sbjct: 683 RLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQL 726
>AF295356-1|AAK71522.1| 527|Homo sapiens moesin/anaplastic lymphoma
kinase fusion protein protein.
Length = 527
Score = 48.8 bits (111), Expect = 5e-05
Identities = 38/180 (21%), Positives = 86/180 (47%), Gaps = 6/180 (3%)
Query: 57 IEREKAD-LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAH 115
+ R K D + VQ ++ R E+ + E N K+ E+ + K E + E EE
Sbjct: 292 MRRRKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEK--EKIEREKEELME 349
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LK+ ++ Q+++++ T+ E+E+ + Q+E +L + + + K + +
Sbjct: 350 RLKQIEEQTK-KAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASR 408
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIE--LVKEVQDLKVNIENVVYLKSQI 233
+ T +L +++ EL I + +Q+ E +E +E+Q +++ +++ Y S++
Sbjct: 409 DQKKTQEQLALEMAELTARISQLEMARQKKESEAVEWQQKQELQAMQMELQSPEYKLSKL 468
Score = 39.5 bits (88), Expect = 0.028
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
A + N +K++ + E E I+ EK EL +R +Q+E + + LEE +
Sbjct: 321 AMLENEKKKREMAEKEKEK--IEREK-----EELMERLKQIEEQTKKAQQELEEQTRRAL 373
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDAL---ARENKKMGDDLHDARANIT 442
+ +++ + Q+E ++++ E + E K+AL +R+ KK + L A +T
Sbjct: 374 ELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELT 425
Score = 38.7 bits (86), Expect = 0.048
Identities = 32/124 (25%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERL---EEAEGGAESQFEINRKRDTELLKLRKLL 103
LE+E++ R+ E+EK + + +L ERL EE A+ + E +R EL + RK
Sbjct: 323 LENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERK-- 380
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENV 163
++ A L K+ QE + +E + Q ++ + + +++ + AE+ ++Q+E
Sbjct: 381 -----RAQSEAEKLAKERQE-AEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMA 434
Query: 164 TKEK 167
++K
Sbjct: 435 RQKK 438
Score = 32.7 bits (71), Expect = 3.2
Identities = 27/119 (22%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
+ L ++E++ + Q +LE + +E+E+ + +L++ +EAE E+ + +
Sbjct: 348 MERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQAS 407
Query: 90 R--KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEK 146
R K+ E L L + E A +KK E V Q+Q Q + + ++ + K
Sbjct: 408 RDQKKTQEQLALEMAELTARISQLEMAR--QKKESEAVEWQQKQELQAMQMELQSPEYK 464
Score = 31.5 bits (68), Expect = 7.3
Identities = 24/99 (24%), Positives = 50/99 (50%), Gaps = 5/99 (5%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLI---IDLEKANGTAR-ELQKRTEQLERVNIEIKSRLEE 387
L+ ++ +E+Q + Q E+E ++LE+ A+ E +K ++ + E K L +
Sbjct: 347 LMERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAE-EAKEALLQ 405
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARE 426
+ ++TQ L + EL +L+ R++K++ A E
Sbjct: 406 ASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAVE 444
>AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluronic
acid binding protein protein.
Length = 724
Score = 48.8 bits (111), Expect = 5e-05
Identities = 51/205 (24%), Positives = 94/205 (45%), Gaps = 12/205 (5%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG-AE 83
E A S + LE ++ ++ L + + + A L Q+I+L+ E + +E
Sbjct: 97 ERGAQDSRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSE 156
Query: 84 SQFEIN-RKRDTELLKLRKLLEDVH---LESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
+ + N R EL+KLR E + +E + + Q + + Q +I QL
Sbjct: 157 NGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKL 216
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
EKEK ++E +LL +E ++ S E+ ++ I++L ++E N I+ +
Sbjct: 217 VSIEKEKIDEKSETEKLLEYIEEIS----CASDQVEKYKLDIAQLEENLKEKNDEILSL- 271
Query: 200 SHKQRLSQENIELVKEVQDLKVNIE 224
KQ L + + L K+V+DL V +
Sbjct: 272 --KQSLEENIVILSKQVEDLNVKCQ 294
Score = 43.6 bits (98), Expect = 0.002
Identities = 74/425 (17%), Positives = 167/425 (39%), Gaps = 26/425 (6%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQV-IQLSERLEEAEGGAESQFE-INR 90
L LE +IR++ + ++ Q +E E + ++ L E+ + A + + I
Sbjct: 84 LKILEKEIRVLLQERGAQDSRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIEL 143
Query: 91 KRDTELLKLRKL----LEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTKTKARAEK 144
R ELLK + +++ + S E L K+ ++ ++ QE ++ + R+ +
Sbjct: 144 TRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLE 203
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E Q ++ +L ++ ++ KEKI E+L I E+ +++ + +DI ++
Sbjct: 204 ES---QGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEEN 260
Query: 205 LSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEID 264
L ++N E++ Q L+ EN+V L Q+ + +
Sbjct: 261 LKEKNDEILSLKQSLE---ENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAE 317
Query: 265 LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXX 324
+++++ + E + R L+++ ++ + + + K
Sbjct: 318 MQNLKQKFILEQQEREKLQQKELQIDSLL-QQEKELSSSLHQKLCSFQEEMVKEKNLFEE 376
Query: 325 XXXXXXTLIAKINNVEKQKSRL--------QSEVEVLIIDLEKANGTARELQKRTEQLER 376
+ K+ E+Q RL +S E L + EK G EL+K + +
Sbjct: 377 ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQ 436
Query: 377 VNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHD 436
+ ++ + + VQ E + + + E++ + + +L + K G + D
Sbjct: 437 ATLLLQEKYDSMVQSLEDVTAQFESYKA---LTASEIEDLKLENSSLQEKAAKAGKNAED 493
Query: 437 ARANI 441
+ I
Sbjct: 494 VQHQI 498
Score = 36.3 bits (80), Expect = 0.26
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 30 LSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEIN 89
LS LE+ I ++ +E Q +E+EK D + + +E L + +F I
Sbjct: 269 LSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKF-IL 327
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
+++ E L+ ++L D L+ E+ L + + FQE ++ K K E+E +
Sbjct: 328 EQQEREKLQQKELQIDSLLQQEKE---LSSSLHQKLCSFQE---EMVKEKNLFEEELKQT 381
Query: 150 QAEVYELL---AQVENVTKEKITISKT-CERLEITISELHIKIEELNRTIVDITSHKQRL 205
E+ +L Q E + K+ +K+ E L++ +L K EL ++ T L
Sbjct: 382 LDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLL 441
Query: 206 SQENIELVKEVQDLKVNIEN 225
++ +V+ ++D+ E+
Sbjct: 442 QEKYDSMVQSLEDVTAQFES 461
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 48.8 bits (111), Expect = 5e-05
Identities = 76/418 (18%), Positives = 165/418 (39%), Gaps = 34/418 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE--AEGGA----ESQ 85
+L+ E + ++Q ++++ LR R+E ++ L+ + Q+ + EE + G +
Sbjct: 509 SLTAKEQRAAILQTEVDA---LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 565
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
++ ++ L K + L++ + E+ LK++ + + D LT T A E
Sbjct: 566 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT-TLEEALAE 624
Query: 146 KSKFQAEVYELLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + + E + E +E+I K + L+ +S L + E +++D+ H
Sbjct: 625 KERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 684
Query: 205 LSQENIELVKEVQDLKVNIEN----VVYLKSQI-----------ASQXXXXXXXXXXXXX 249
L+ ++ ++ L++ +E + ++SQ+ AS
Sbjct: 685 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 744
Query: 250 XXXXXXASLHQVEID-----LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXX 304
+S Q E+D L+ V + ++ + +LERQ+ N ++ + + K
Sbjct: 745 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEK 804
Query: 305 XXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKAN 361
+ +L K + +E+ + L+ V++ + L +
Sbjct: 805 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 864
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+K+ E+L ++K LE TQ+ L K+T L + E K E+
Sbjct: 865 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 922
Score = 44.0 bits (99), Expect = 0.001
Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREK-----------ADLSVQVIQLSERLEEAE 79
+AL+ LE+ + + +E +E R R EREK DL +V L L E E
Sbjct: 613 TALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 672
Query: 80 GG-------AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----ID 127
A S K+D+ L L LE E + LKK ++ + +
Sbjct: 673 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 732
Query: 128 FQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK 187
++I L + R + E SK QAEV LL ++ V EK K I+EL +
Sbjct: 733 MSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK-------KIAELERQ 785
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+++ N+ + ++ +Q +++ ++++E + + N+ +
Sbjct: 786 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 823
Score = 42.7 bits (96), Expect = 0.003
Identities = 70/406 (17%), Positives = 145/406 (35%), Gaps = 15/406 (3%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E QR+ E + ++ L + LEE E E+Q + RD + KL ++L+
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
L ++ T ++ + + + + + L + EKE S + E++ + K K
Sbjct: 321 LSAKATEEDHERTRR--LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTK 378
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ E + IS + + +L I + S+ ++E E +K+++ + + + +
Sbjct: 379 -ALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK 437
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
Q+ + A + QV+ +L +L L Q
Sbjct: 438 NKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFS 497
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQ 347
+ I + +I ++ ++K
Sbjct: 498 DSKQHIEVLKESLTAKEQRAAILQTEVDA-LRLRLEEKETMLNKKTKQIQDMAEEKGTQA 556
Query: 348 SEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E+ L L+ LQK+ E L+ + + ++ + + Q D N T L
Sbjct: 557 GEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Query: 408 RVSHEL-------DKTREQKDALARENKKMGD----DLHDARANIT 442
+ L ++ +EQ+D RE ++ D DL D + ++
Sbjct: 617 TLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVS 662
Score = 42.3 bits (95), Expect = 0.004
Identities = 75/409 (18%), Positives = 163/409 (39%), Gaps = 27/409 (6%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ +QD+L +R+L Q +++ + + + ++E EE ++ E K EL L
Sbjct: 229 IQALQDELRIQRDLNQLFQQDSSSRTGEPC-VAELTEENFQRLHAEHERQAK---ELFLL 284
Query: 100 RKLLEDVHLESEETAHLLKKKNQEI--VIDFQEQIDQLTK-TKARAEKEKSKFQAE--VY 154
RK LE++ L E L +++ I +++ + K T+ E+ + +AE V+
Sbjct: 285 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVH 344
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI-ELV 213
L + +E KE + + R + K + L +T++++ K + + +L
Sbjct: 345 HLESLLEQKEKENSMLREEMHR-RFENAPDSAKTKAL-QTVIEMKDSKISSMERGLRDLE 402
Query: 214 KEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLE 273
+E+Q LK N + + Q + Q++ +L S Q E
Sbjct: 403 EEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKN-------KVEQLKEELSSKEAQWE 455
Query: 274 EESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLI 333
E + L+ ++ G++ S+ ++S +L
Sbjct: 456 ELKKKAAGLQAEI----GQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLT 511
Query: 334 AKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYE 393
AK E++ + LQ+EV+ L + LE+ + K+ + + + + + +
Sbjct: 512 AK----EQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLD 567
Query: 394 QTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANIT 442
+R + Q +++ + +L +Q +L K + D + +T
Sbjct: 568 VKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT 616
Score = 37.5 bits (83), Expect = 0.11
Identities = 62/368 (16%), Positives = 141/368 (38%), Gaps = 15/368 (4%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E+ +R E + +Q +++++ + + + + + ++LK L E E
Sbjct: 363 EMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEE 422
Query: 112 ETAHLLKKKNQEIVIDFQEQI-DQLTKTKARAEKEKSK---FQAEVYELLAQVENVTKEK 167
+ + + + + + EQ+ ++L+ +A+ E+ K K QAE+ ++ ++ E
Sbjct: 423 MKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDTEL 482
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+ + E L S+ IE L + +T+ +QR + L EV L++ +E
Sbjct: 483 LALQTKLETLTNQFSDSKQHIEVLKES---LTAKEQRAA----ILQTEVDALRLRLEEKE 535
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
+ ++ Q L E + ++ ++E E D E+Q+
Sbjct: 536 TMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS 595
Query: 288 KANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAK---INNVEKQKS 344
+ ++ K K I+N +K
Sbjct: 596 SLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLK 655
Query: 345 RLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQT 404
L+ +V +L DL + + +L++ L ++ SRL+ EQ + + ++
Sbjct: 656 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 715
Query: 405 ELQRVSHE 412
+L++ +HE
Sbjct: 716 QLKK-AHE 722
Score = 34.7 bits (76), Expect = 0.79
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 16/193 (8%)
Query: 39 KIRLIQDDLESERELRQRIEREKADLS--VQVIQLSERLEEAEGGAE-SQFEINRKRDTE 95
K + +Q +E + +ER DL +Q+++ + L E E Q E+ R
Sbjct: 376 KTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKF 435
Query: 96 LL-KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ K+ +L E++ + + L KK Q +I Q+ + +R + E Q ++
Sbjct: 436 MKNKVEQLKEELSSKEAQWEELKKK-----AAGLQAEIGQVKQELSRKDTELLALQTKLE 490
Query: 155 ELLAQVEN------VTKEKITISKT-CERLEITISELHIKIEELNRTIVDITSHKQRLSQ 207
L Q + V KE +T + L+ + L +++EE + T Q +++
Sbjct: 491 TLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE 550
Query: 208 ENIELVKEVQDLK 220
E E+ DLK
Sbjct: 551 EKGTQAGEIHDLK 563
Score = 33.5 bits (73), Expect = 1.8
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 13/192 (6%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E S + + RL + ++ ++++ + + +ER+ D + +V L + + + +
Sbjct: 750 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 809
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-IDFQEQIDQLTKTKARAE 143
E R+R+ L + L+D + ++ L++ +E V I + ++ + AR
Sbjct: 810 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 869
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
EK +V ELL +E V +E E ++ +S + E + ++ + ++
Sbjct: 870 AEK-----QVEELLMAMEKVKQE-------LESMKAKLSSTQQSLAEKETHLTNLRAERR 917
Query: 204 RLSQENIELVKE 215
+ +E +E+ +E
Sbjct: 918 KHLEEVLEMKQE 929
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 48.8 bits (111), Expect = 5e-05
Identities = 76/418 (18%), Positives = 165/418 (39%), Gaps = 34/418 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEE--AEGGA----ESQ 85
+L+ E + ++Q ++++ LR R+E ++ L+ + Q+ + EE + G +
Sbjct: 481 SLTAKEQRAAILQTEVDA---LRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDM 537
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
++ ++ L K + L++ + E+ LK++ + + D LT T A E
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALT-TLEEALAE 596
Query: 146 KSKFQAEVYELLAQVENVTKEKI-TISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
K + + E + E +E+I K + L+ +S L + E +++D+ H
Sbjct: 597 KERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 656
Query: 205 LSQENIELVKEVQDLKVNIEN----VVYLKSQI-----------ASQXXXXXXXXXXXXX 249
L+ ++ ++ L++ +E + ++SQ+ AS
Sbjct: 657 LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI 716
Query: 250 XXXXXXASLHQVEID-----LESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXX 304
+S Q E+D L+ V + ++ + +LERQ+ N ++ + + K
Sbjct: 717 TRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEK 776
Query: 305 XXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLI---IDLEKAN 361
+ +L K + +E+ + L+ V++ + L +
Sbjct: 777 KKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEE 836
Query: 362 GTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
+K+ E+L ++K LE TQ+ L K+T L + E K E+
Sbjct: 837 SARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEE 894
Score = 47.2 bits (107), Expect = 1e-04
Identities = 67/382 (17%), Positives = 144/382 (37%), Gaps = 12/382 (3%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVH 107
E E QR+ E + ++ L + LEE E E+Q + RD + KL ++L+
Sbjct: 261 ELTEENFQRLHAEHERQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKG 320
Query: 108 LESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEK 167
L ++ T ++ + + + + + L + EKE S + E++ + K K
Sbjct: 321 LSAKATEEDHERTRR--LAEAEMHVHHLESLLEQKEKENSMLREEMHRRFENAPDSAKTK 378
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVN---IE 224
+ E + IS + + +L I + S+ ++E E +K+++ + + ++
Sbjct: 379 -ALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK 437
Query: 225 NVV-YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES--EARLD 281
N + +K +++ + S +E+ ES+ + + + + +D
Sbjct: 438 NKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVD 497
Query: 282 LERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEK 341
R ++ + + ++K L KI N+++
Sbjct: 498 ALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQE 557
Query: 342 QKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRN 401
Q + ++ L ++ LE E + +E +L EQ RD R
Sbjct: 558 QLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIE---RLKEQRDRDERE 614
Query: 402 KQTELQRVSHELDKTREQKDAL 423
KQ E+ +L +E+ L
Sbjct: 615 KQEEIDNYKKDLKDLKEKVSLL 636
Score = 44.0 bits (99), Expect = 0.001
Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 30/218 (13%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREK-----------ADLSVQVIQLSERLEEAE 79
+AL+ LE+ + + +E +E R R EREK DL +V L L E E
Sbjct: 585 TALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 644
Query: 80 GG-------AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-----ID 127
A S K+D+ L L LE E + LKK ++ + +
Sbjct: 645 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPE 704
Query: 128 FQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIK 187
++I L + R + E SK QAEV LL ++ V EK K I+EL +
Sbjct: 705 MSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDK-------KIAELERQ 757
Query: 188 IEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIEN 225
+++ N+ + ++ +Q +++ ++++E + + N+ +
Sbjct: 758 VKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLND 795
Score = 33.5 bits (73), Expect = 1.8
Identities = 36/192 (18%), Positives = 87/192 (45%), Gaps = 13/192 (6%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E S + + RL + ++ ++++ + + +ER+ D + +V L + + + +
Sbjct: 722 ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQ 781
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV-IDFQEQIDQLTKTKARAE 143
E R+R+ L + L+D + ++ L++ +E V I + ++ + AR
Sbjct: 782 MLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTN 841
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
EK +V ELL +E V +E E ++ +S + E + ++ + ++
Sbjct: 842 AEK-----QVEELLMAMEKVKQE-------LESMKAKLSSTQQSLAEKETHLTNLRAERR 889
Query: 204 RLSQENIELVKE 215
+ +E +E+ +E
Sbjct: 890 KHLEEVLEMKQE 901
>AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2
protein.
Length = 1390
Score = 48.8 bits (111), Expect = 5e-05
Identities = 43/201 (21%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+ ++ +Q + S + ++ EK L + EE + GA + E + +E
Sbjct: 750 LQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGAR-RLEEGTEETSE 808
Query: 96 LLKLRKLLEDVHLESEETAHL------LKKKNQEIVIDFQEQ---IDQLTKTKARAEKEK 146
L+ KL E++ ++S + HL LKK+ Q+I F +Q ++ + ++
Sbjct: 809 TLE--KLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLI 866
Query: 147 SKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLS 206
S+ +A L ++++ + +E + + E +S LH ++ ++ + + D+ H Q
Sbjct: 867 SELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQ 926
Query: 207 QENIELVKEVQDLKVNIENVV 227
+E E+ +Q L+ + E +V
Sbjct: 927 KERDEMETHLQSLQFDKEQMV 947
Score = 45.2 bits (102), Expect = 6e-04
Identities = 43/189 (22%), Positives = 80/189 (42%), Gaps = 8/189 (4%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
A + +E+ ++ ++ E ERE QR+ A L Q+ Q+ L + + Q E ++
Sbjct: 662 AKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQ----RDQQLEALQQ 717
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
+L+K L ++ E++ L+ E+ Q ++ +L A E Q
Sbjct: 718 EHLDLMKQLTLTQEALQSREQSLDALQTHYDEL----QARLGELQGEAASREDTICLLQN 773
Query: 152 EVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIE 211
E L A ++ K + + RLE E +E+L + + + L QE
Sbjct: 774 EKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAA 833
Query: 212 LVKEVQDLK 220
L K++Q +K
Sbjct: 834 LKKQMQKIK 842
Score = 44.8 bits (101), Expect = 7e-04
Identities = 61/334 (18%), Positives = 124/334 (37%), Gaps = 15/334 (4%)
Query: 110 SEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKIT 169
+EET+ L+K +E+ I Q++ L + A +K+ K + + + VE ++ +
Sbjct: 803 TEETSETLEKLREELAIK-SGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATS 861
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYL 229
+ L+ T L +++EL + ++ + K+ E L +EV ++ +++ L
Sbjct: 862 KDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVR---QHMADL 918
Query: 230 KSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEE-ESEARLDLERQLVK 288
+ + S + E + E+++ Q+EE + EAR + Q K
Sbjct: 919 EGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEAN-EALKKQIEELQQEARKAITEQKQK 977
Query: 289 ANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQS 348
+G + S A++ + Q S
Sbjct: 978 MR-RLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDS 1036
Query: 349 EVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQR 408
+ + E+ ELQ + ++ L+E + L Q + R K EL+
Sbjct: 1037 SLALH----ERIQALEAELQA----VSHSKTLLEKELQEVIALTSQELEESREKVLELED 1088
Query: 409 VSHELDKTREQKDALARENKKMGDDLHDARANIT 442
E R++ L NKK+ +L + +T
Sbjct: 1089 ELQESRGFRKKIKRLEESNKKLALELEHEKGKLT 1122
Score = 40.7 bits (91), Expect = 0.012
Identities = 56/245 (22%), Positives = 114/245 (46%), Gaps = 31/245 (12%)
Query: 65 SVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLES-EETAHLLKKKNQE 123
S++ + + E + G E E+ +RD+ + LE E+ EE +LK+K +
Sbjct: 360 SIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVS--LESSAAETQEEMLQVLKEKMR- 416
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSKFQAEV----YELLAQVE----------NVTKEKIT 169
+ Q++ L+ ++A KEK++ QA++ +L AQVE +++ E T
Sbjct: 417 ----LEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDT 472
Query: 170 ISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLK---VNIENV 226
+ ++C LE +++L +E N ++ + Q ++ L+ +V+D++ ++ +N
Sbjct: 473 LKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNT 532
Query: 227 VY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR----VQLEEESEARLD 281
V+ L+ Q+ + AS ++ L+SVR QL EAR+
Sbjct: 533 VHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEIS-SLQSVRQWYQQQLALAQEARVR 591
Query: 282 LERQL 286
L+ ++
Sbjct: 592 LQGEM 596
Score = 33.5 bits (73), Expect = 1.8
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 134 QLTKTKARAEKEKSKFQAEVYELLAQV--ENVTKEKITISKTC--ERLEITISELHIKIE 189
QLT+T+ R+ KEK + A++ + A + + +I +KT E L+ + E + E
Sbjct: 623 QLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERE 682
Query: 190 ELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQI 233
L R S +Q+L Q + L++ Q L+ + + L Q+
Sbjct: 683 RLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQL 726
>Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.
Length = 1356
Score = 48.4 bits (110), Expect = 6e-05
Identities = 77/419 (18%), Positives = 166/419 (39%), Gaps = 29/419 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T + + SA+L+ L +D RL+ + E +L+Q E +K + QL +L+EA
Sbjct: 436 TNQLESKQSAELNKLR--QDYARLVNELTEKTGKLQQE-EVQKKNAEQAATQLKVQLQEA 492
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI---DFQEQIDQL 135
E E RKR E ++ L+ + E L K + ++ ++++ QL
Sbjct: 493 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL 552
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE----------KITISKTCERLEITISELH 185
+++ + ++ Q +V ++L Q E + + + + S E L I+E
Sbjct: 553 MESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-- 610
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENVVYLKSQIASQXXXXX 241
K +++ +T + S + RL+ + EL K++Q+ LK ++ + L ++ A+
Sbjct: 611 -KDKQIKQTEDSLASERDRLTSKEEEL-KDIQNMNFLLKAEVQKLQALANEQAAAAHELE 668
Query: 242 XXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
Q++ ++ + + + ++ L+ ++ K + +K
Sbjct: 669 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV 728
Query: 302 XXXXXXXXXXXXXXXK-YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA 360
K T ++N + + S L EV+ DL+
Sbjct: 729 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ----DLKAK 784
Query: 361 NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
E+L++V E +++ +L E + NK+ +Q + E+ +E+
Sbjct: 785 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 843
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ ++ + LQ E E L + G ++LQ+ EQ E + K +++E+ + +Q
Sbjct: 1120 KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEEN---KWKVKVDESHKTIKQ 1176
Query: 395 TQRDLRNKQTELQRVSHE---LDKTREQKDALARENKK 429
Q + + EL+R+ E ++ R +++ L E +K
Sbjct: 1177 MQSSFTSSEQELERLRSENKDIENLRREREHLEMELEK 1214
Score = 33.1 bits (72), Expect = 2.4
Identities = 71/402 (17%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 30 LSALSRLEDKIRLIQDDLE--SERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQ 85
L + L++K +IQD L+ S+ EL I + EK L V + + ++ +
Sbjct: 301 LCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQE 360
Query: 86 FEINRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
++R ++ K LE H + H+ ++ Q++ + FQ+ +Q+ A
Sbjct: 361 MMTEKERSNVVMTRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 420
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++E + V Q+E +K+ ++K + ++EL K +L + V +
Sbjct: 421 LKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA 478
Query: 202 KQRLSQENIELV------KEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+Q +Q ++L +EVQ ++ + + S+
Sbjct: 479 EQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDT 538
Query: 255 XASLHQVE------IDLESVRVQLEEESEARL-DLERQLVKANGEIGHWRSKFXXXXXXX 307
S Q+E ++ E RV EE + ++ D+ Q +I + S+
Sbjct: 539 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 598
Query: 308 --XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
+ + ++ + E++ +Q+ +L +++K A
Sbjct: 599 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 658
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E +LE++ + + ++ L EQ Q ++ NK E +
Sbjct: 659 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 700
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/160 (18%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+ V +E + ++ ++ + EI H + + K S
Sbjct: 393 IHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 452
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L+ N + ++ +LQ E + + A A +L+ + ++ ER E++S + +
Sbjct: 453 DYARLV---NELTEKTGKLQQEE----VQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 505
Query: 388 TVQLYEQTQRDLRNK----QTELQRVSHELDKTREQKDAL 423
+E Q+DL++K + E+Q + +L T K L
Sbjct: 506 RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 545
Score = 31.9 bits (69), Expect = 5.5
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ KI+ +++ LE+E E+ DL ++ L E + + Q I K +
Sbjct: 806 DGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSK----V 861
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEI------VIDFQEQIDQLTKTKARAEKEKSKFQ 150
+L+ LL+ + +L++K +++ + D QE+ + L K + + + +
Sbjct: 862 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL-KAHVQEVAQHNLKE 920
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
A ++E V KEK +RLE + E + + + D+ + +L + I
Sbjct: 921 ASSASQFEELEIVLKEK---GNELKRLEAMLKERESDLSSKTQLLQDV-QDENKLFKSQI 976
Query: 211 ELVKE 215
E +K+
Sbjct: 977 EQLKQ 981
>X14487-1|CAA32649.1| 593|Homo sapiens protein ( Human gene for
acidic (type I) cytokeratin 10. ).
Length = 593
Score = 48.4 bits (110), Expect = 6e-05
Identities = 45/205 (21%), Positives = 96/205 (46%), Gaps = 13/205 (6%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
AD++ L R+ D++ L + DLE + E + E A L + + L G + E
Sbjct: 250 ADINGLRRVLDELTLTKADLEMQIE---SLTEELAYLKKNHEEEMKDLRNVSTG-DVNVE 305
Query: 88 INRKRDTELLKL----RKLLEDVHLESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARA 142
+N +L +L R E + ++ + A +K++E+ + I+Q++ K+
Sbjct: 306 MNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEI 365
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
+ + QA EL +Q+ + ++++T R + +S++H +I L + I +
Sbjct: 366 TELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIHAQISALEEQLQQIRAET 425
Query: 203 QRLSQENIELVKEVQDLKVNIENVV 227
+ + E +L+ D+K+ +EN +
Sbjct: 426 ECQNTEYQQLL----DIKIRLENEI 446
>L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.
Length = 1300
Score = 48.4 bits (110), Expect = 6e-05
Identities = 77/419 (18%), Positives = 166/419 (39%), Gaps = 29/419 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T + + SA+L+ L +D RL+ + E +L+Q E +K + QL +L+EA
Sbjct: 437 TNQLESKQSAELNKLR--QDYARLVNELTEKTGKLQQE-EVQKKNAEQAATQLKVQLQEA 493
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI---DFQEQIDQL 135
E E RKR E ++ L+ + E L K + ++ ++++ QL
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE----------KITISKTCERLEITISELH 185
+++ + ++ Q +V ++L Q E + + + + S E L I+E
Sbjct: 554 MESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-- 611
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENVVYLKSQIASQXXXXX 241
K +++ +T + S + RL+ + EL K++Q+ LK ++ + L ++ A+
Sbjct: 612 -KDKQIKQTEDSLASERDRLTSKEEEL-KDIQNMNFLLKAEVQKLQALANEQAAAAHELE 669
Query: 242 XXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
Q++ ++ + + + ++ L+ ++ K + +K
Sbjct: 670 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV 729
Query: 302 XXXXXXXXXXXXXXXK-YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA 360
K T ++N + + S L EV+ DL+
Sbjct: 730 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ----DLKAK 785
Query: 361 NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
E+L++V E +++ +L E + NK+ +Q + E+ +E+
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 844
Score = 40.7 bits (91), Expect = 0.012
Identities = 64/329 (19%), Positives = 127/329 (38%), Gaps = 15/329 (4%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
+E +LLK K +++ + +++ K A K Q E L A V+ V + +
Sbjct: 863 QELQNLLKGKEEQMNT-MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 921
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENV 226
+ + + E L K EL R + + LS + +L+++VQD K IE +
Sbjct: 922 ASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKT-QLLQDVQDENKLFKSQIEQL 980
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
Q AS ++++ ++V Q ++ +E + +E
Sbjct: 981 KQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVE 1040
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX---XXXXXXXXXXTLIAKINNVEKQK 343
++A + K K + L K+ ++
Sbjct: 1041 LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH 1100
Query: 344 SRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQ 403
+ LQ E E L + G ++LQ+ EQ E + K +++E+ + +Q Q + +
Sbjct: 1101 TLLQLECEKYKSVLAETEGILQKLQRSVEQEEN---KWKVKVDESHKTIKQMQSSFTSSE 1157
Query: 404 TELQRVSHE---LDKTREQKDALARENKK 429
EL+R+ E ++ R +++ L E +K
Sbjct: 1158 QELERLRSENKDIENLRREREHLEMELEK 1186
Score = 36.3 bits (80), Expect = 0.26
Identities = 27/129 (20%), Positives = 62/129 (48%), Gaps = 2/129 (1%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELL 97
+++++++ L+ E+ ++ E + + L++ + E + + + E
Sbjct: 1084 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESH 1143
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELL 157
K K ++ SE+ L+ +N++I + + + + L +AE E+S + EV EL
Sbjct: 1144 KTIKQMQSSFTSSEQELERLRSENKDIE-NLRREREHLEMELEKAEMERSTYVTEVRELK 1202
Query: 158 AQV-ENVTK 165
AQ+ E +TK
Sbjct: 1203 AQLNETLTK 1211
Score = 34.3 bits (75), Expect = 1.0
Identities = 73/419 (17%), Positives = 164/419 (39%), Gaps = 25/419 (5%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+V +E + LS S++++ L++ E ++ +E ++ DL+ L + EE E
Sbjct: 847 NVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 906
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
E+ + E + E++ + +E + LK+ + ++ + + + T+
Sbjct: 907 LKAHVQEVAQHNLKEASSASQF-EELEIVLKEKENELKRL-EAMLKERESDLSSKTQLLQ 964
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL-NR--TIVD 197
+ E F++++ +L Q ++ + E L ISE +I L N ++ D
Sbjct: 965 DVQDENKLFKSQIEQLKQQ----NYQQASSFPPHEELLKVISEREKEISGLWNELDSLKD 1020
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
H+++ + E + V+ V+ + ++ K + S +
Sbjct: 1021 AVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGT 1080
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
E+ + +++ +E L LE + K+ ++ K
Sbjct: 1081 SGSEEVKVLEHKLKEADEMHTLLQLECEKYKSV------LAETEGILQKLQRSVEQEENK 1134
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ + + + E++ RL+SE + D+E RE + +LE+
Sbjct: 1135 WKVKVDESHKTIKQMQSSFTSSEQELERLRSENK----DIENLR---REREHLEMELEKA 1187
Query: 378 NIEIKSRLEETVQLYEQ---TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
+E + + E +L Q T LR +Q E Q+V+ +L K ++ + + + K D
Sbjct: 1188 EMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGD 1246
Score = 33.1 bits (72), Expect = 2.4
Identities = 71/402 (17%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 30 LSALSRLEDKIRLIQDDLE--SERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQ 85
L + L++K +IQD L+ S+ EL I + EK L V + + ++ +
Sbjct: 302 LCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQE 361
Query: 86 FEINRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
++R ++ K LE H + H+ ++ Q++ + FQ+ +Q+ A
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++E + V Q+E +K+ ++K + ++EL K +L + V +
Sbjct: 422 LKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA 479
Query: 202 KQRLSQENIELV------KEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+Q +Q ++L +EVQ ++ + + S+
Sbjct: 480 EQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDT 539
Query: 255 XASLHQVE------IDLESVRVQLEEESEARL-DLERQLVKANGEIGHWRSKFXXXXXXX 307
S Q+E ++ E RV EE + ++ D+ Q +I + S+
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 308 --XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
+ + ++ + E++ +Q+ +L +++K A
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 659
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E +LE++ + + ++ L EQ Q ++ NK E +
Sbjct: 660 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/160 (18%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+ V +E + ++ ++ + EI H + + K S
Sbjct: 394 IHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 453
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L+ N + ++ +LQ E + + A A +L+ + ++ ER E++S + +
Sbjct: 454 DYARLV---NELTEKTGKLQQEE----VQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 388 TVQLYEQTQRDLRNK----QTELQRVSHELDKTREQKDAL 423
+E Q+DL++K + E+Q + +L T K L
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 546
>J04029-1|AAA60544.1| 561|Homo sapiens keratin 10 protein.
Length = 561
Score = 48.4 bits (110), Expect = 6e-05
Identities = 44/205 (21%), Positives = 96/205 (46%), Gaps = 13/205 (6%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
AD++ L R+ D++ L Q DLE + E + E A L + + L G + E
Sbjct: 243 ADINGLRRVLDELTLTQADLEMQIE---SLTEELAYLKKNREEEMKHLRNVSTG-DVNVE 298
Query: 88 INRKRDTELLKL----RKLLEDVHLESEETAHL-LKKKNQEIVIDFQEQIDQLTKTKARA 142
+N +L +L R E + ++ + A +K++E+ + I+Q++ K+
Sbjct: 299 MNAAPGVDLTQLLNNMRNQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEI 358
Query: 143 EKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
+ + QA EL +Q+ + ++++T R + +S++ +I L + +I +
Sbjct: 359 TELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQEIRAET 418
Query: 203 QRLSQENIELVKEVQDLKVNIENVV 227
+ + E +++ D+K+ +EN +
Sbjct: 419 ECQNTE----YQQLTDIKIRLENEI 439
Score = 32.3 bits (70), Expect = 4.2
Identities = 22/110 (20%), Positives = 48/110 (43%)
Query: 117 LKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCER 176
L++ N E+ +E+ DQ ++ ++ SK+ + +L Q+ N+T + I +
Sbjct: 160 LEESNYELEGKIKERYDQHGNSRQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDN 219
Query: 177 LEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
+ + +K E + + L + EL DL++ IE++
Sbjct: 220 ARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTQADLEMQIESL 269
>D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.
Length = 1307
Score = 48.4 bits (110), Expect = 6e-05
Identities = 77/419 (18%), Positives = 166/419 (39%), Gaps = 29/419 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T + + SA+L+ L +D RL+ + E +L+Q E +K + QL +L+EA
Sbjct: 444 TNQLESKQSAELNKLR--QDYARLVNELTEKTGKLQQE-EVQKKNAEQAATQLKVQLQEA 500
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI---DFQEQIDQL 135
E E RKR E ++ L+ + E L K + ++ ++++ QL
Sbjct: 501 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL 560
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE----------KITISKTCERLEITISELH 185
+++ + ++ Q +V ++L Q E + + + + S E L I+E
Sbjct: 561 MESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-- 618
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENVVYLKSQIASQXXXXX 241
K +++ +T + S + RL+ + EL K++Q+ LK ++ + L ++ A+
Sbjct: 619 -KDKQIKQTEDSLASERDRLTSKEEEL-KDIQNMNFLLKAEVQKLQALANEQAAAAHELE 676
Query: 242 XXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
Q++ ++ + + + ++ L+ ++ K + +K
Sbjct: 677 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV 736
Query: 302 XXXXXXXXXXXXXXXK-YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA 360
K T ++N + + S L EV+ DL+
Sbjct: 737 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ----DLKAK 792
Query: 361 NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
E+L++V E +++ +L E + NK+ +Q + E+ +E+
Sbjct: 793 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 851
Score = 40.7 bits (91), Expect = 0.012
Identities = 64/329 (19%), Positives = 127/329 (38%), Gaps = 15/329 (4%)
Query: 111 EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITI 170
+E +LLK K +++ + +++ K A K Q E L A V+ V + +
Sbjct: 870 QELQNLLKGKEEQMNT-MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKE 928
Query: 171 SKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENV 226
+ + + E L K EL R + + LS + +L+++VQD K IE +
Sbjct: 929 ASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKT-QLLQDVQDENKLFKSQIEQL 987
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
Q AS ++++ ++V Q ++ +E + +E
Sbjct: 988 KQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNERQQQVEAVE 1047
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX---XXXXXXXXXXTLIAKINNVEKQK 343
++A + K K + L K+ ++
Sbjct: 1048 LEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMH 1107
Query: 344 SRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQ 403
+ LQ E E L + G ++LQ+ EQ E + K +++E+ + +Q Q + +
Sbjct: 1108 TLLQLECEKYKSVLAETEGILQKLQRSVEQEEN---KWKVKVDESHKTIKQMQSSFTSSE 1164
Query: 404 TELQRVSHE---LDKTREQKDALARENKK 429
EL+R+ E ++ R +++ L E +K
Sbjct: 1165 QELERLRSENKDIENLRREREHLEMELEK 1193
Score = 36.3 bits (80), Expect = 0.26
Identities = 27/129 (20%), Positives = 62/129 (48%), Gaps = 2/129 (1%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELL 97
+++++++ L+ E+ ++ E + + L++ + E + + + E
Sbjct: 1091 EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESH 1150
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELL 157
K K ++ SE+ L+ +N++I + + + + L +AE E+S + EV EL
Sbjct: 1151 KTIKQMQSSFTSSEQELERLRSENKDIE-NLRREREHLEMELEKAEMERSTYVTEVRELK 1209
Query: 158 AQV-ENVTK 165
AQ+ E +TK
Sbjct: 1210 AQLNETLTK 1218
Score = 34.3 bits (75), Expect = 1.0
Identities = 73/419 (17%), Positives = 164/419 (39%), Gaps = 25/419 (5%)
Query: 21 DVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEG 80
+V +E + LS S++++ L++ E ++ +E ++ DL+ L + EE E
Sbjct: 854 NVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENES 913
Query: 81 GAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKA 140
E+ + E + E++ + +E + LK+ + ++ + + + T+
Sbjct: 914 LKAHVQEVAQHNLKEASSASQF-EELEIVLKEKENELKRL-EAMLKERESDLSSKTQLLQ 971
Query: 141 RAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEEL-NR--TIVD 197
+ E F++++ +L Q ++ + E L ISE +I L N ++ D
Sbjct: 972 DVQDENKLFKSQIEQLKQQ----NYQQASSFPPHEELLKVISEREKEISGLWNELDSLKD 1027
Query: 198 ITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXAS 257
H+++ + E + V+ V+ + ++ K + S +
Sbjct: 1028 AVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGT 1087
Query: 258 LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXK 317
E+ + +++ +E L LE + K+ ++ K
Sbjct: 1088 SGSEEVKVLEHKLKEADEMHTLLQLECEKYKSV------LAETEGILQKLQRSVEQEENK 1141
Query: 318 YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV 377
+ + + + E++ RL+SE + D+E RE + +LE+
Sbjct: 1142 WKVKVDESHKTIKQMQSSFTSSEQELERLRSENK----DIENLR---REREHLEMELEKA 1194
Query: 378 NIEIKSRLEETVQLYEQ---TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDD 433
+E + + E +L Q T LR +Q E Q+V+ +L K ++ + + + K D
Sbjct: 1195 EMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGD 1253
Score = 33.1 bits (72), Expect = 2.4
Identities = 71/402 (17%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 30 LSALSRLEDKIRLIQDDLE--SERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQ 85
L + L++K +IQD L+ S+ EL I + EK L V + + ++ +
Sbjct: 309 LCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQE 368
Query: 86 FEINRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
++R ++ K LE H + H+ ++ Q++ + FQ+ +Q+ A
Sbjct: 369 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 428
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++E + V Q+E +K+ ++K + ++EL K +L + V +
Sbjct: 429 LKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA 486
Query: 202 KQRLSQENIELV------KEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+Q +Q ++L +EVQ ++ + + S+
Sbjct: 487 EQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDT 546
Query: 255 XASLHQVE------IDLESVRVQLEEESEARL-DLERQLVKANGEIGHWRSKFXXXXXXX 307
S Q+E ++ E RV EE + ++ D+ Q +I + S+
Sbjct: 547 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 606
Query: 308 --XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
+ + ++ + E++ +Q+ +L +++K A
Sbjct: 607 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 666
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E +LE++ + + ++ L EQ Q ++ NK E +
Sbjct: 667 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 708
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/160 (18%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+ V +E + ++ ++ + EI H + + K S
Sbjct: 401 IHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 460
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L+ N + ++ +LQ E + + A A +L+ + ++ ER E++S + +
Sbjct: 461 DYARLV---NELTEKTGKLQQEE----VQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 513
Query: 388 TVQLYEQTQRDLRNK----QTELQRVSHELDKTREQKDAL 423
+E Q+DL++K + E+Q + +L T K L
Sbjct: 514 RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 553
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 48.4 bits (110), Expect = 6e-05
Identities = 47/255 (18%), Positives = 112/255 (43%), Gaps = 28/255 (10%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI------NR 90
E++ +Q ++E+ L++R++ DL + ++ E+ GA S +++ N
Sbjct: 181 EERAESLQQEVEA---LKERVDELTTDLEILKAEIEEK---GSDGAASSYQLKQLEEQNA 234
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ L+++R L E + L++KKNQE+ + Q+ + R ++E S+ +
Sbjct: 235 RLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ--------RERLQEELSQAE 286
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ + EL QV+ + + +R + + E K+ EL T+ D+ + +++ N
Sbjct: 287 STIDELKEQVDAALGAEEMVEMLTDR-NLNLEE---KVRELRETVGDL----EAMNEMND 338
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL + ++ ++ + + + + Q+ +L+ V
Sbjct: 339 ELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTANLQDVNR 398
Query: 271 QLEEESEARLDLERQ 285
+L + EA ++ ++Q
Sbjct: 399 ELTNQQEASVERQQQ 413
Score = 45.6 bits (103), Expect = 4e-04
Identities = 77/371 (20%), Positives = 140/371 (37%), Gaps = 39/371 (10%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E+ L QV L E+LE + KR + KL++L + H E K
Sbjct: 81 KEEEGLRAQVRDLEEKLET----------LRLKRAEDKAKLKEL--EKHKIQLEQVQEWK 128
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
K QE D Q ++ + K A + K ++ E+ + +E T +K + E L+
Sbjct: 129 SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQ 188
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXX 238
+ L +++EL D+ K + ++ + LK E LK +
Sbjct: 189 QEVEALKERVDELT---TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 245
Query: 239 XXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-SEARLDLERQLVKANGEIGHWR 297
++E+ + R +L+EE S+A ++ + + +G
Sbjct: 246 LSSSEKQEHVKLQKLMEKKNQELEV-VRQQRERLQEELSQAESTIDELKEQVDAALG--- 301
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
+ + ++N+ E Q++ ++E+E L L
Sbjct: 302 ----AEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMND-ELQENARETELE-LREQL 355
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ A RE QKR E + ETV Y+QT + R LQ V+ EL T
Sbjct: 356 DMAGARVREAQKRVEAAQ-----------ETVADYQQTIKKYRQLTANLQDVNREL--TN 402
Query: 418 EQKDALARENK 428
+Q+ ++ R+ +
Sbjct: 403 QQEASVERQQQ 413
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ + +LE R+ R+R++ E + + +L E+++ A GAE E+ R+
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL-GAEEMVEMLTDRNL 314
Query: 95 EL-LKLRKLLEDV-HLES-EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
L K+R+L E V LE+ E L++ +E ++ +EQ+D A+K Q
Sbjct: 315 NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQE 374
Query: 152 EV 153
V
Sbjct: 375 TV 376
>BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein.
Length = 873
Score = 48.4 bits (110), Expect = 6e-05
Identities = 77/419 (18%), Positives = 166/419 (39%), Gaps = 29/419 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T + + SA+L+ L +D RL+ + E +L+Q E +K + QL +L+EA
Sbjct: 437 TNQLESKQSAELNKLR--QDYARLVNELTEKTGKLQQE-EVQKKNAEQAATQLKVQLQEA 493
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI---DFQEQIDQL 135
E E RKR E ++ L+ + E L K + ++ ++++ QL
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE----------KITISKTCERLEITISELH 185
+++ + ++ Q +V ++L Q E + + + + S E L I+E
Sbjct: 554 MESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-- 611
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENVVYLKSQIASQXXXXX 241
K +++ +T + S + RL+ + EL K++Q+ LK ++ + L ++ A+
Sbjct: 612 -KDKQIKQTEDSLASERDRLTSKEEEL-KDIQNMNFLLKAEVQKLQALANEQAAAAHELE 669
Query: 242 XXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
Q++ ++ + + + ++ L+ ++ K + +K
Sbjct: 670 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV 729
Query: 302 XXXXXXXXXXXXXXXK-YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA 360
K T ++N + + S L EV+ DL+
Sbjct: 730 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ----DLKAK 785
Query: 361 NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
E+L++V E +++ +L E + NK+ +Q + E+ +E+
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 844
Score = 33.1 bits (72), Expect = 2.4
Identities = 71/402 (17%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 30 LSALSRLEDKIRLIQDDLE--SERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQ 85
L + L++K +IQD L+ S+ EL I + EK L V + + ++ +
Sbjct: 302 LCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQE 361
Query: 86 FEINRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
++R ++ K LE H + H+ ++ Q++ + FQ+ +Q+ A
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++E + V Q+E +K+ ++K + ++EL K +L + V +
Sbjct: 422 LKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA 479
Query: 202 KQRLSQENIELV------KEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+Q +Q ++L +EVQ ++ + + S+
Sbjct: 480 EQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDT 539
Query: 255 XASLHQVE------IDLESVRVQLEEESEARL-DLERQLVKANGEIGHWRSKFXXXXXXX 307
S Q+E ++ E RV EE + ++ D+ Q +I + S+
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 308 --XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
+ + ++ + E++ +Q+ +L +++K A
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 659
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E +LE++ + + ++ L EQ Q ++ NK E +
Sbjct: 660 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/160 (18%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+ V +E + ++ ++ + EI H + + K S
Sbjct: 394 IHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 453
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L+ N + ++ +LQ E + + A A +L+ + ++ ER E++S + +
Sbjct: 454 DYARLV---NELTEKTGKLQQEE----VQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 388 TVQLYEQTQRDLRNK----QTELQRVSHELDKTREQKDAL 423
+E Q+DL++K + E+Q + +L T K L
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 546
>AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1
protein.
Length = 1357
Score = 48.4 bits (110), Expect = 6e-05
Identities = 77/419 (18%), Positives = 166/419 (39%), Gaps = 29/419 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T + + SA+L+ L +D RL+ + E +L+Q E +K + QL +L+EA
Sbjct: 437 TNQLESKQSAELNKLR--QDYARLVNELTEKTGKLQQE-EVQKKNAEQAATQLKVQLQEA 493
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVI---DFQEQIDQL 135
E E RKR E ++ L+ + E L K + ++ ++++ QL
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQL 553
Query: 136 TKTKARAEKEKSKFQAEVYELLAQVENVTKE----------KITISKTCERLEITISELH 185
+++ + ++ Q +V ++L Q E + + + + S E L I+E
Sbjct: 554 MESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAE-- 611
Query: 186 IKIEELNRTIVDITSHKQRLSQENIELVKEVQD----LKVNIENVVYLKSQIASQXXXXX 241
K +++ +T + S + RL+ + EL K++Q+ LK ++ + L ++ A+
Sbjct: 612 -KDKQIKQTEDSLASERDRLTSKEEEL-KDIQNMNFLLKAEVQKLQALANEQAAAAHELE 669
Query: 242 XXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFX 301
Q++ ++ + + + ++ L+ ++ K + +K
Sbjct: 670 KMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDV 729
Query: 302 XXXXXXXXXXXXXXXK-YSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKA 360
K T ++N + + S L EV+ DL+
Sbjct: 730 VEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ----DLKAK 785
Query: 361 NGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQ 419
E+L++V E +++ +L E + NK+ +Q + E+ +E+
Sbjct: 786 QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEE 844
Score = 34.3 bits (75), Expect = 1.0
Identities = 24/98 (24%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ ++ + LQ E E L + G ++LQ+ EQ E + K +++E+ + +Q
Sbjct: 1121 KLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEEN---KWKVKVDESHKTIKQ 1177
Query: 395 TQRDLRNKQTELQRVSHE---LDKTREQKDALARENKK 429
Q + + EL+R+ E ++ R +++ L E +K
Sbjct: 1178 MQSSFTSSEQELERLRSENKDIENLRREREHLEMELEK 1215
Score = 33.1 bits (72), Expect = 2.4
Identities = 71/402 (17%), Positives = 154/402 (38%), Gaps = 26/402 (6%)
Query: 30 LSALSRLEDKIRLIQDDLE--SERELRQRIER--EKADLSVQVIQLSERLEEAEGGAESQ 85
L + L++K +IQD L+ S+ EL I + EK L V + + ++ +
Sbjct: 302 LCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQLTQE 361
Query: 86 FEINRKRDTELLKLRK----LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
++R ++ K LE H + H+ ++ Q++ + FQ+ +Q+ A
Sbjct: 362 MMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAH 421
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
++E + V Q+E +K+ ++K + ++EL K +L + V +
Sbjct: 422 LKQENGILRDAVSNTTNQLE--SKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNA 479
Query: 202 KQRLSQENIELV------KEVQD-LKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXX 254
+Q +Q ++L +EVQ ++ + + S+
Sbjct: 480 EQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDT 539
Query: 255 XASLHQVE------IDLESVRVQLEEESEARL-DLERQLVKANGEIGHWRSKFXXXXXXX 307
S Q+E ++ E RV EE + ++ D+ Q +I + S+
Sbjct: 540 LVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSAS 599
Query: 308 --XXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTAR 365
+ + ++ + E++ +Q+ +L +++K A
Sbjct: 600 VLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALAN 659
Query: 366 ELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQ 407
E +LE++ + + ++ L EQ Q ++ NK E +
Sbjct: 660 EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFK 701
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/160 (18%), Positives = 64/160 (40%), Gaps = 11/160 (6%)
Query: 268 VRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+ V +E + ++ ++ + EI H + + K S
Sbjct: 394 IHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 453
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
L+ N + ++ +LQ E + + A A +L+ + ++ ER E++S + +
Sbjct: 454 DYARLV---NELTEKTGKLQQEE----VQKKNAEQAATQLKVQLQEAERRWEEVQSYIRK 506
Query: 388 TVQLYEQTQRDLRNK----QTELQRVSHELDKTREQKDAL 423
+E Q+DL++K + E+Q + +L T K L
Sbjct: 507 RTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQL 546
Score = 31.9 bits (69), Expect = 5.5
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTEL 96
+ KI+ +++ LE+E E+ DL ++ L E + + Q I K +
Sbjct: 807 DGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSK----V 862
Query: 97 LKLRKLLEDVHLESEETAHLLKKKNQEI------VIDFQEQIDQLTKTKARAEKEKSKFQ 150
+L+ LL+ + +L++K +++ + D QE+ + L K + + + +
Sbjct: 863 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL-KAHVQEVAQHNLKE 921
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
A ++E V KEK +RLE + E + + + D+ + +L + I
Sbjct: 922 ASSASQFEELEIVLKEK---ENELKRLEAMLKERESDLSSKTQLLQDV-QDENKLFKSQI 977
Query: 211 ELVKE 215
E +K+
Sbjct: 978 EQLKQ 982
>AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil
domain containing 1 protein.
Length = 1478
Score = 48.4 bits (110), Expect = 6e-05
Identities = 39/180 (21%), Positives = 82/180 (45%), Gaps = 4/180 (2%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
+ + Q +S + + R E +D + ++ +L E+L+ E E+NR++ +L +L
Sbjct: 372 LAMAQQKADSASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQL 431
Query: 100 RK---LLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYEL 156
K L ED E + +E+ QE DQL + S ++ E+ EL
Sbjct: 432 VKELQLKEDARASLERLVKEMAPLQEELSGKGQEA-DQLWRRLQELLAHTSSWEEELAEL 490
Query: 157 LAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+ + +EK + + L + L ++ ++++ + D+ K++L Q+ L ++V
Sbjct: 491 RREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQV 550
Score = 37.1 bits (82), Expect = 0.15
Identities = 44/207 (21%), Positives = 87/207 (42%), Gaps = 7/207 (3%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+AL RLE ++ + +LE+ R+ + + A + ++ + A Q I
Sbjct: 335 TALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADSASDTKGRQEPIPS 394
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQL-TKTKARAEKEKSKF 149
E+ +L + L+ LE E T +++ N++ ++ + +L K ARA E +
Sbjct: 395 DAAQEMQELGEKLQ--ALERERTK--VEEVNRQQSAQLEQLVKELQLKEDARASLE--RL 448
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
E+ L ++ +E + + + L S ++ EL R K+ L QE
Sbjct: 449 VKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEV 508
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQ 236
L +++Q L+ + V S + Q
Sbjct: 509 RSLTRQLQFLETQLAQVSQHVSDLEEQ 535
Score = 34.7 bits (76), Expect = 0.79
Identities = 39/170 (22%), Positives = 74/170 (43%), Gaps = 11/170 (6%)
Query: 19 TTDVNIEYSADLSALSRLEDK----IRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T ++ I+ A R+E+ ++ +QD E+ R+ +ER+ A L + L E+
Sbjct: 905 TAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEK 964
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQ 134
L+ A+ A S + + + + L E H E + LK + ++D+Q +
Sbjct: 965 LKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQE----LNTLKFQLSAEIMDYQ---SR 1017
Query: 135 LTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISEL 184
L + + + + + +L A E V K K T + E+L T + L
Sbjct: 1018 LKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHL 1067
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal
Nek2-associated protein 1 protein.
Length = 2442
Score = 48.4 bits (110), Expect = 6e-05
Identities = 85/427 (19%), Positives = 169/427 (39%), Gaps = 34/427 (7%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E L L + ++R + +L+ + + Q + ++ + ++ ERL+E G E+
Sbjct: 474 ELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEDQQEELHLAVRERERLQEMLMGLEA 533
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDF---QEQIDQLTKTKAR 141
+ + +EL+ LR+ LE HLE E LL+++ E+ ++ I +L+ ++
Sbjct: 534 K---QSESLSELITLREALESSHLEGE----LLRQEQTEVTAALARAEQSIAELSSSENT 586
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE----ITISELHIKIEELNRTIVD 197
+ E + +A +L A E + +K+ +++ +LE S + + N VD
Sbjct: 587 LKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVD 646
Query: 198 ITSHKQR---LSQENIELVKEVQ-------DLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
+ ++R L ++N L ++Q +L+ ++ ++ K +I +
Sbjct: 647 LAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKK----LSESRHQ 702
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
LHQ E V + +E EA + + L + R
Sbjct: 703 QEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGL 762
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXT---LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTA 364
T L +I V + K +Q EV L ++L+ A
Sbjct: 763 SSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQA 822
Query: 365 -RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+E QL + E K+ LE+ +E+ LR K E +R H+ + + ++L
Sbjct: 823 EQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREK-WEKERSWHQ-QELAKALESL 880
Query: 424 ARENKKM 430
RE ++
Sbjct: 881 EREKMEL 887
Score = 47.6 bits (108), Expect = 1e-04
Identities = 81/378 (21%), Positives = 149/378 (39%), Gaps = 43/378 (11%)
Query: 73 ERLEEAEGGAESQ-----FEINRKRDTELLKLRKLLEDVHLESEETA-HLLKK---KNQE 123
E E GG +S E ++ L K LL + E+ +A H L + K Q+
Sbjct: 1198 ESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQ 1257
Query: 124 IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISE 183
++Q+ +L + E EKS+ E+ +L Q+ +EK LE + E
Sbjct: 1258 TRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELME 1317
Query: 184 LHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXX 243
LH T+ + S +R + +E E + L+ EN L +Q+
Sbjct: 1318 LH-------ETMASLQSRLRRAELQRMEAQGERELLQAAKEN---LTAQVEHLQAAVVEA 1367
Query: 244 XXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXX 303
+E DL + R L+ ++E ++ ER+ +A E G +
Sbjct: 1368 RAQASAAGI--------LEEDLRTARSALKLKNE-EVESERERAQALQEQGELK------ 1412
Query: 304 XXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGT 363
+ TL +I +EKQ+ ++ +E+L +DL+K N
Sbjct: 1413 -VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQE 1471
Query: 364 A-------RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKT 416
+EL+K LE + + ++ R ++ EQ + ++++T+ + H+L +
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLEL 1531
Query: 417 REQKDALARENKKMGDDL 434
E+KD + + DL
Sbjct: 1532 -EKKDQMIESQRGQVQDL 1548
Score = 45.6 bits (103), Expect = 4e-04
Identities = 65/272 (23%), Positives = 118/272 (43%), Gaps = 15/272 (5%)
Query: 25 EYSADLSALSR--LEDKIRLIQDDLESERELRQRIE-REKADLSVQVIQLS---ERLEEA 78
E + L +L R +E ++RL + E E QR E R +A+ ++ +QL ER+
Sbjct: 872 ELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL 931
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
E ++Q E+ +L +LR+ ++ L+ +ET +L+ + QE + +E Q
Sbjct: 932 ETLLQTQKEL-ADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD 990
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
A ++E S + +L QVE++ + + + +E + E + +E NR ++
Sbjct: 991 LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKEL 1050
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
K L+ + L+++ Q L V ++ ++ Q S L
Sbjct: 1051 EREKASLT---LSLMEKEQRLLV-LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELL 1106
Query: 259 HQ----VEIDLESVRVQLEEESEARLDLERQL 286
Q E D + QL EE EA E+QL
Sbjct: 1107 RQEVKEKEADFLAQEAQLLEELEASHITEQQL 1138
Score = 45.2 bits (102), Expect = 6e-04
Identities = 64/412 (15%), Positives = 154/412 (37%), Gaps = 16/412 (3%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+ L + ++ ++ + +S R + L + + L+ E Q E++R
Sbjct: 1933 AVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSR 1992
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKS 147
+ L+ L+ S + L+ + EI + +QE + QL + A+ ++E
Sbjct: 1993 SLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEEL- 2051
Query: 148 KFQAEVYELLAQV------ENVTKEKITISKTCERLEI-----TISELHIKIEELNRTIV 196
+ Q E +LL + EN+ +EK + + E EI ++ EL + + + + I+
Sbjct: 2052 RHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEIL 2111
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++ +QR + E + + ++ + L+ ++ +
Sbjct: 2112 ELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWRE 2171
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ + L + + E + L+ +++ + E + +
Sbjct: 2172 KAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPG 2231
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
S + +++ VE + S E + LE L+ +L+R
Sbjct: 2232 ATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQR 2291
Query: 377 VNIEIKSRLEETVQLYEQTQRD-LRNKQTELQRVSHELDKTREQKDALAREN 427
N++++S LE+ + + +R+ +R Q +S + Q+D ++N
Sbjct: 2292 HNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKN 2343
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/406 (17%), Positives = 167/406 (41%), Gaps = 23/406 (5%)
Query: 33 LSRLEDKIRLIQ-DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
++ L+ ++R + +E++ E R+ ++ K +L+ QV L + EA A + +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGE-RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEED 1380
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID--FQEQIDQLTKTKARAEKEKSKF 149
T L+ E+V E E L ++ ++ QE + LT+T A E+E
Sbjct: 1381 LRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETL 1440
Query: 150 QAEVYELLAQ--VENVTKEKITISKTCERLEITISELHIKIEELNRTIVD-----ITSHK 202
+ ++ EL Q ++ E +++ E+ + + I+ E R++++ + +
Sbjct: 1441 RGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQERE 1500
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L+ + E ++E++ + NV L+ Q+ L +
Sbjct: 1501 QKLTVQR-EQIRELEKDRETQRNV--LEHQLLE-----LEKKDQMIESQRGQVQDLKKQL 1552
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
+ LE + ++L EE+ +++ +++L+K E + +
Sbjct: 1553 VTLECLALEL-EENHHKMECQQKLIK-ELEGQRETQRVALTHLTLDLEERSQELQAQSSQ 1610
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
T++A+ Q+ + Q E ++ + +K + T ++L++R ++L I+
Sbjct: 1611 IHDLESHSTVLARELQERDQEVKSQRE-QIEELQRQKEHLT-QDLERRDQELMLQKERIQ 1668
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
++ + + + DL + L+ EL R+ A E K
Sbjct: 1669 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714
Score = 40.3 bits (90), Expect = 0.016
Identities = 61/298 (20%), Positives = 111/298 (37%), Gaps = 17/298 (5%)
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LL K QE+ + E+ +L + K++ + EK++ Q V EL A + K+ K +
Sbjct: 248 LLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIK 307
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
L T ++I E N T ++ H+ LS+ E +Q + +I V+ + +
Sbjct: 308 ALRET-----VEILETNHT--ELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIA 360
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q + L VR L +A DL +QL +
Sbjct: 361 QGSGHENSLELDSSIFSQF--DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLII 355
+ + K + L +++++ K++ LQ E L
Sbjct: 419 LQQQ-HDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE L++ +L RVN+E++ + + E Q +L E +R+ L
Sbjct: 478 QLE-------VLEQEAWRLRRVNVELQLQGDSAQGQKEDQQEELHLAVRERERLQEML 528
Score = 40.3 bits (90), Expect = 0.016
Identities = 73/449 (16%), Positives = 177/449 (39%), Gaps = 32/449 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
+ES+R Q ++++ L ++L E + E + E+ +R+T+ + L L D+
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
S+E L+ ++ +I ++ + AR +E+ + EV Q+E + ++
Sbjct: 1598 EERSQE----LQAQSSQI-----HDLESHSTVLARELQERDQ---EVKSQREQIEELQRQ 1645
Query: 167 KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
K +++ ER + EL ++ E + + + D + + ++ +E++E +K L+ +
Sbjct: 1646 KEHLTQDLERRD---QELMLQKERI-QVLEDQRTRQTKILEEDLEQIK--LSLRERGREL 1699
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
+ + + L E ++E + + E E + LE+QL
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQL 1759
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRL 346
+ ++G + + +L ++++ ++ ++
Sbjct: 1760 QGLHRKVG----ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+E L + ++A G ++++ + L+ LE+ ++ +L++ + +
Sbjct: 1816 DQELEALQQEQQQAQGQEERVKEKADALQ-------GALEQAHMTLKERHGELQDHKEQA 1868
Query: 407 QRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXT 466
+R+ EL + AL + +GD ++R
Sbjct: 1869 RRLEEELAVEGRRVQAL---EEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 467 AAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
++ +A+A K +Q + L AE RH
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRH 1954
Score = 38.3 bits (85), Expect = 0.064
Identities = 79/419 (18%), Positives = 164/419 (39%), Gaps = 45/419 (10%)
Query: 20 TDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAE 79
T+V + +++ L ++ ++ R ++ L++ + L+++L + E
Sbjct: 564 TEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLE 623
Query: 80 GGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTK 139
E+Q +R E + R L+ E+E+ L +KN + Q
Sbjct: 624 --EENQSVCSRMEAAE--QARNALQVDLAEAEKRREALWEKNTHLEAQLQ---------- 669
Query: 140 ARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDIT 199
+AE+ ++ QA++ ++ + E + K+ +S++ + E ++L E+L++
Sbjct: 670 -KAEEAGAELQADLRDIQEEKEEIQKK---LSESRHQQEAATTQL----EQLHQEAKRQE 721
Query: 200 SHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLH 259
R QE LV+E L+V ++ V + +A Q
Sbjct: 722 EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Query: 260 QVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYS 319
+E+ + VQ++ ++A+ ++ ++ E+ RS+ +
Sbjct: 782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGK 841
Query: 320 XXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANG-TARELQKRTEQLERVN 378
+E+QK+ + EV L EK +EL K E LER
Sbjct: 842 TA-----------------LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREK 884
Query: 379 IEIKSRLEETVQLYE--QTQRDLRNKQTELQRVSHELDKTREQ---KDALARENKKMGD 432
+E++ RL+E E Q QR+ Q E +L+ +E+ + L + K++ D
Sbjct: 885 MELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELAD 943
Score = 37.1 bits (82), Expect = 0.15
Identities = 64/402 (15%), Positives = 158/402 (39%), Gaps = 18/402 (4%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ ++ E++R + + + S ++ S ++ + E + ++RD E+
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ 1635
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV-YELLA 158
R+ +E++ + E L++++QE+++ +E+I L + R K + ++ L
Sbjct: 1636 REQIEELQRQKEHLTQDLERRDQELMLQ-KERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1694
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ +T ++ + + E + +E + + D K++ + E + E+Q+
Sbjct: 1695 RGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRD----KEKEVECQQEHIHELQE 1750
Query: 219 LKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESE 277
LK +E + L ++ + Q E+ +S++ QL+E
Sbjct: 1751 LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1810
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
A +++L E + + + ++
Sbjct: 1811 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERH--------GELQ 1862
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+ ++Q RL+ E+ V ++ +L+ + + E+ + ++ + E Q +E R
Sbjct: 1863 DHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETR 1922
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
L++ + Q V E D ++ +AL E++ ARA
Sbjct: 1923 ALQDSWLQAQAVLKERD---QELEALRAESQSSRHQEEAARA 1961
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 48.0 bits (109), Expect = 8e-05
Identities = 81/422 (19%), Positives = 172/422 (40%), Gaps = 23/422 (5%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIERE--KADLSVQVIQLSERLEEAEGGAESQ 85
++ +A LE + Q E+ R+L+ ++ + + + + ++S + E + E
Sbjct: 71 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 130
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + ++ KL+KL E E+ L KK Q +FQEQ+ ++ K+++E
Sbjct: 131 DVMKKSSEEQIAKLQKLHEKELARKEQE---LTKKLQTREREFQEQM-KVALEKSQSEYL 186
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K + E E LA E ++K ++++ +L +L + E I+++ S ++
Sbjct: 187 KISQEKEQQESLALEELELQKKAILTESENKLR----DLQQEAETYRTRILELESSLEKS 242
Query: 206 SQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
QEN K++ + + N N+ + Q +
Sbjct: 243 LQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 302
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRS------KFXXXXXXXXXXXXXXXX 316
++E +R + E+E E L + + +A+ E + ++ K
Sbjct: 303 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 362
Query: 317 KYSXXXXXXXXXXXTLIAKIN---NVEKQKSRLQSEVEVLIIDLEKA-NGTARELQKRTE 372
++ T K +++QK+ Q +V+ +I + E + T + L+ +
Sbjct: 363 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 422
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
QLE + E L+E E + D++ + ELQ+ S +LD + + A + K +
Sbjct: 423 QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 482
Query: 433 DL 434
L
Sbjct: 483 QL 484
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/396 (18%), Positives = 161/396 (40%), Gaps = 22/396 (5%)
Query: 32 ALSRLEDKIRLIQDDLESERELR-QRIE-REKADLSVQVIQLSERLEEAEGGAESQFEIN 89
AL + + + I + E + L + +E ++KA L+ +L + +EAE E+
Sbjct: 177 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELE 236
Query: 90 RKRDTELLKLRKLLED--VHLESEETAH-----LLKKKNQEIVIDFQEQIDQLTKTKARA 142
+ L + + +D VHLE+E+ H ++ +K++ + + Q D L K +
Sbjct: 237 SSLEKSLQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQV 296
Query: 143 EKEKSKFQAEVYELLAQVENVT----KEKITISKTCERLEITISELHIK---IEELNRTI 195
K++ + + E + E T KE I + E E T+ +L +K +E L+ +
Sbjct: 297 LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 356
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ + +L +E L + +K +E + + Q
Sbjct: 357 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA 416
Query: 256 AS--LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++Q+E+ L+ L+E +LE + ++ GE+ +K
Sbjct: 417 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 476
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
Y L + + KQ + ++++ + + +L+ ++L +Q
Sbjct: 477 TKA-YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM---QQ 532
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LE+ N E++ +++ Q+YE D +Q + +++
Sbjct: 533 LEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 568
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 48.0 bits (109), Expect = 8e-05
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 34/322 (10%)
Query: 120 KNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEI 179
K Q+ ++Q+ +L + E EKS+ E+ +L Q+ +EK LE
Sbjct: 1254 KTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLES 1313
Query: 180 TISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXX 239
+ ELH T+ + S +R + +E E + L+ EN L +Q+
Sbjct: 1314 ELMELH-------ETMASLQSRLRRAELQRMEAQGERELLQAAKEN---LTAQVEHLQAA 1363
Query: 240 XXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSK 299
+E DL + R L+ ++E ++ ER+ +A E G +
Sbjct: 1364 VVEARAQASAAGI--------LEEDLRTARSALKLKNE-EVESERERAQALQEQGELK-- 1412
Query: 300 FXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEK 359
+ TL +I +EKQ+ ++ +E+L +DL+K
Sbjct: 1413 -----VAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKK 1467
Query: 360 ANGTA-------RELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHE 412
N +EL+K LE + + ++ R ++ EQ + ++++T+ + H+
Sbjct: 1468 RNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIREPEKDRETQRNVLEHQ 1527
Query: 413 LDKTREQKDALARENKKMGDDL 434
L + E+KD + + DL
Sbjct: 1528 LLEL-EKKDQMIESQRGQVQDL 1548
Score = 45.6 bits (103), Expect = 4e-04
Identities = 65/272 (23%), Positives = 118/272 (43%), Gaps = 15/272 (5%)
Query: 25 EYSADLSALSR--LEDKIRLIQDDLESERELRQRIE-REKADLSVQVIQLS---ERLEEA 78
E + L +L R +E ++RL + E E QR E R +A+ ++ +QL ER+
Sbjct: 872 ELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL 931
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKT 138
E ++Q E+ +L +LR+ ++ L+ +ET +L+ + QE + +E Q
Sbjct: 932 ETLLQTQKEL-ADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDD 990
Query: 139 KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDI 198
A ++E S + +L QVE++ + + + +E + E + +E NR ++
Sbjct: 991 LAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKEL 1050
Query: 199 TSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASL 258
K L+ + L+++ Q L V ++ ++ Q S L
Sbjct: 1051 EREKASLT---LSLMEKEQRLLV-LQEADSIRQQELSALRQDMQEAQGEQKELSAQMELL 1106
Query: 259 HQ----VEIDLESVRVQLEEESEARLDLERQL 286
Q E D + QL EE EA E+QL
Sbjct: 1107 RQEVKEKEADFLAQEAQLLEELEASHITEQQL 1138
Score = 45.2 bits (102), Expect = 6e-04
Identities = 84/410 (20%), Positives = 158/410 (38%), Gaps = 23/410 (5%)
Query: 24 IEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAE 83
+E+ A LS ++ E+K+ L Q +++ Q + E+ D Q L LE E
Sbjct: 324 MEHEASLSRNAQ-EEKLSLQQ----VIKDITQ-VMVEEGDNIAQGSGLENSLE-LESSIF 376
Query: 84 SQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAE 143
SQF+ + D L +R +L ++ L QE V Q+Q DQ +
Sbjct: 377 SQFDY-QDADKALTLVRSVLTRRRQAVQDLRQQLAGC-QEAVNLLQQQHDQWEEEGKALR 434
Query: 144 KEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
+ K E L Q ++ E ++SK E L+ EL ++E L +
Sbjct: 435 QRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQ-------EAW 487
Query: 204 RLSQENIELVKE---VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQ 260
RL + N+EL + Q K + ++L + + +L +
Sbjct: 488 RLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLRE 547
Query: 261 VEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSX 320
LES+ ++ E + + ++ L +A I S K S
Sbjct: 548 A---LESIHLEGELLRQEQTEVTAALARAEQSIAELSSS-ENTLKTEVADLRAAAVKLSA 603
Query: 321 XXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIE 380
L ++ +E++ + S +E E +KR E L N
Sbjct: 604 LNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTH 663
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKM 430
++++L++ + + Q DLR+ Q E + + +L ++R Q++A + +++
Sbjct: 664 LEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 713
Score = 44.0 bits (99), Expect = 0.001
Identities = 64/412 (15%), Positives = 153/412 (37%), Gaps = 16/412 (3%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
+ L + ++ ++ + +S R + L + + L+ E Q E++R
Sbjct: 1933 AVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSR 1992
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIV---IDFQEQIDQLTKTKARAEKEKS 147
+ L+ L+ S + L+ + EI + +QE + QL + A+ ++E
Sbjct: 1993 SLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEEL- 2051
Query: 148 KFQAEVYELLAQV------ENVTKEKITISKTCERLEI-----TISELHIKIEELNRTIV 196
+ Q E +LL + EN+ +EK + E EI ++ EL + + + + I+
Sbjct: 2052 RHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRGLHQSVRELQLTLAQKEQEIL 2111
Query: 197 DITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXA 256
++ +QR + E + + ++ + L+ ++ +
Sbjct: 2112 ELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWRE 2171
Query: 257 SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXX 316
+ + L + + E + L+ +++ + E + +
Sbjct: 2172 KAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPG 2231
Query: 317 KYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLER 376
S + +++ VE + S E + LE L+ +L+R
Sbjct: 2232 ATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQR 2291
Query: 377 VNIEIKSRLEETVQLYEQTQRD-LRNKQTELQRVSHELDKTREQKDALAREN 427
N++++S LE+ + + +R+ +R Q +S + Q+D ++N
Sbjct: 2292 HNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKN 2343
Score = 41.1 bits (92), Expect = 0.009
Identities = 61/298 (20%), Positives = 112/298 (37%), Gaps = 17/298 (5%)
Query: 116 LLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCE 175
LL K QE+ + E+ +L + K++ + EK++ Q V EL A + K+ K +
Sbjct: 248 LLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIK 307
Query: 176 RLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIAS 235
L T ++I E N T ++ H+ LS+ E +Q + +I V+ + +
Sbjct: 308 ALRET-----VEILETNHT--ELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIA 360
Query: 236 QXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGH 295
Q + L VR L +A DL +QL +
Sbjct: 361 QGSGLENSLELESSIFSQF--DYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNL 418
Query: 296 WRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLII 355
+ + K + L +++++ K++ LQ E L
Sbjct: 419 LQQQ-HDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQ 477
Query: 356 DLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL 413
LE L++ +L RVN+E++ + + E+ Q +L E +R+ L
Sbjct: 478 QLE-------VLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEML 528
Score = 40.3 bits (90), Expect = 0.016
Identities = 73/449 (16%), Positives = 177/449 (39%), Gaps = 32/449 (7%)
Query: 47 LESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDV 106
+ES+R Q ++++ L ++L E + E + E+ +R+T+ + L L D+
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 107 HLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE 166
S+E L+ ++ +I ++ + AR +E+ + EV Q+E + ++
Sbjct: 1598 EERSQE----LQAQSSQI-----HDLESHSTVLARELQERDQ---EVKSQREQIEELQRQ 1645
Query: 167 KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENV 226
K +++ ER + EL ++ E + + + D + + ++ +E++E +K L+ +
Sbjct: 1646 KEHLTQDLERRD---QELMLQKERI-QVLEDQRTRQTKILEEDLEQIK--LSLRERGREL 1699
Query: 227 VYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQL 286
+ + + L E ++E + + E E + LE+QL
Sbjct: 1700 TTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQL 1759
Query: 287 VKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRL 346
+ ++G + + +L ++++ ++ ++
Sbjct: 1760 QGLHRKVG----ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQR 1815
Query: 347 QSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTEL 406
E+E L + ++A G ++++ + L+ LE+ ++ +L++ + +
Sbjct: 1816 DQELEALQQEQQQAQGQEERVKEKADALQ-------GALEQAHMTLKERHGELQDHKEQA 1868
Query: 407 QRVSHELDKTREQKDALARENKKMGDDLHDARANITXXXXXXXXXXXXXXXXXXXXXXXT 466
+R+ EL + AL + +GD ++R
Sbjct: 1869 RRLEEELAVEGRRVQAL---EEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQ 1925
Query: 467 AAYKEAEAGRKAEEQRSQRLTAEFGQFRH 495
++ +A+A K +Q + L AE RH
Sbjct: 1926 DSWLQAQAVLKERDQELEALRAESQSSRH 1954
Score = 39.5 bits (88), Expect = 0.028
Identities = 73/406 (17%), Positives = 166/406 (40%), Gaps = 23/406 (5%)
Query: 33 LSRLEDKIRLIQ-DDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRK 91
++ L+ ++R + +E++ E R+ ++ K +L+ QV L + EA A + +
Sbjct: 1322 MASLQSRLRRAELQRMEAQGE-RELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEED 1380
Query: 92 RDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVID--FQEQIDQLTKTKARAEKEKSKF 149
T L+ E+V E E L ++ ++ QE + LT+T A E+E
Sbjct: 1381 LRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETL 1440
Query: 150 QAEVYELLAQ--VENVTKEKITISKTCERLEITISELHIKIEELNRTIVD-----ITSHK 202
+ ++ EL Q ++ E +++ E+ + + I+ E R++++ + +
Sbjct: 1441 RGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQERE 1500
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
Q+L+ + E ++E + + NV L+ Q+ L +
Sbjct: 1501 QKLTVQR-EQIREPEKDRETQRNV--LEHQLLE-----LEKKDQMIESQRGQVQDLKKQL 1552
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
+ LE + ++L EE+ +++ +++L+K E + +
Sbjct: 1553 VTLECLALEL-EENHHKMECQQKLIK-ELEGQRETQRVALTHLTLDLEERSQELQAQSSQ 1610
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIK 382
T++A+ Q+ + Q E ++ + +K + T ++L++R ++L I+
Sbjct: 1611 IHDLESHSTVLARELQERDQEVKSQRE-QIEELQRQKEHLT-QDLERRDQELMLQKERIQ 1668
Query: 383 SRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENK 428
++ + + + DL + L+ EL R+ A E K
Sbjct: 1669 VLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGK 1714
Score = 37.9 bits (84), Expect = 0.084
Identities = 24/87 (27%), Positives = 38/87 (43%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
EK++ L + L L+KA ELQ ++ EI+ +L E+ E L
Sbjct: 651 EKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQL 710
Query: 400 RNKQTELQRVSHELDKTREQKDALARE 426
E +R L + ++K+AL RE
Sbjct: 711 EQLHQEAKRQEEVLARAVQEKEALVRE 737
Score = 37.1 bits (82), Expect = 0.15
Identities = 64/402 (15%), Positives = 158/402 (39%), Gaps = 18/402 (4%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I+ ++ E++R + + + S ++ S ++ + E + ++RD E+
Sbjct: 1576 IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ 1635
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEV-YELLA 158
R+ +E++ + E L++++QE+++ +E+I L + R K + ++ L
Sbjct: 1636 REQIEELQRQKEHLTQDLERRDQELMLQ-KERIQVLEDQRTRQTKILEEDLEQIKLSLRE 1694
Query: 159 QVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQD 218
+ +T ++ + + E + +E + + D K++ + E + E+Q+
Sbjct: 1695 RGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRD----KEKEVECQQEHIHELQE 1750
Query: 219 LKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESE 277
LK +E + L ++ + Q E+ +S++ QL+E
Sbjct: 1751 LKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQR 1810
Query: 278 ARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKIN 337
A +++L E + + + ++
Sbjct: 1811 ALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERH--------GELQ 1862
Query: 338 NVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQR 397
+ ++Q RL+ E+ V ++ +L+ + + E+ + ++ + E Q +E R
Sbjct: 1863 DHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETR 1922
Query: 398 DLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
L++ + Q V E D ++ +AL E++ ARA
Sbjct: 1923 ALQDSWLQAQAVLKERD---QELEALRAESQSSRHQEEAARA 1961
Score = 35.9 bits (79), Expect = 0.34
Identities = 42/192 (21%), Positives = 87/192 (45%), Gaps = 7/192 (3%)
Query: 48 ESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQF-EINRKRDTELLKLRKLLEDV 106
++E+E + +E++KA +V QL E+ E+ + + + + E ++L L++
Sbjct: 835 QAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQ 894
Query: 107 HLESEE-TAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTK 165
E E A +++ Q Q Q+ + K + + + Q E+ + Q+E + +
Sbjct: 895 QTEMEAIQAQREEERTQAESALCQMQL-ETEKERVSLLETLLQTQKELADASQQLERLRQ 953
Query: 166 E-KITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIE 224
+ K+ K E I ++L EL L +E+ L+++ DL+ +E
Sbjct: 954 DMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVE 1013
Query: 225 NVVYLKSQIASQ 236
+ LKSQ+ +Q
Sbjct: 1014 D---LKSQLVAQ 1022
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/396 (18%), Positives = 161/396 (40%), Gaps = 22/396 (5%)
Query: 32 ALSRLEDKIRLIQDDLESERELR-QRIE-REKADLSVQVIQLSERLEEAEGGAESQFEIN 89
AL + + + I + E + L + +E ++KA L+ +L + +EAE E+
Sbjct: 545 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELE 604
Query: 90 RKRDTELLKLRKLLED--VHLESEETAH-----LLKKKNQEIVIDFQEQIDQLTKTKARA 142
+ L + + +D VHLE+E+ H ++ +K++ + + Q D L K +
Sbjct: 605 SSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 664
Query: 143 EKEKSKFQAEVYELLAQVENVT----KEKITISKTCERLEITISELHIK---IEELNRTI 195
K++ + + E + E T KE I + E E T+ +L +K +E L+ +
Sbjct: 665 LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 724
Query: 196 VDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXX 255
++ + +L +E L + +K +E + + Q
Sbjct: 725 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA 784
Query: 256 AS--LHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXX 313
++Q+E+ L+ L+E +LE + ++ GE+ +K
Sbjct: 785 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQ 844
Query: 314 XXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQ 373
Y L + + KQ + ++++ + + +L+ ++L +Q
Sbjct: 845 TKA-YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLM---QQ 900
Query: 374 LERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRV 409
LE+ N E++ +++ Q+YE D +Q + +++
Sbjct: 901 LEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 936
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/407 (20%), Positives = 177/407 (43%), Gaps = 41/407 (10%)
Query: 46 DLESERELRQR----IEREKADLSVQV----IQLSERLEEAEGGAESQFEINRKRDTELL 97
DLE+ER L + +E +K D+ ++ IQ+ + +++ E S+ E K T++
Sbjct: 861 DLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK-QNSEMEQKVKSLTQVY 919
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQE----QIDQLTKTKARAEKEKSKFQAEV 153
+ + LED + E E+T +L +K + +++ +E +I+ LT+ K A+++ E
Sbjct: 920 ESK--LEDGNKEQEQTKQILVEK-ENMILQMREGQKKEIEILTQ-KLSAKEDSIHILNEE 975
Query: 154 YE--LLAQVENVTKEKITISKTCERLEITISELHIKIE-ELNRTIVDITSHKQRLSQENI 210
YE Q + + K K + E L+ + + K++ EL T ++++ Q+ Q N
Sbjct: 976 YETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELS---QKEKQFNA 1032
Query: 211 ELVKEVQDLKVNIENVVY-LKSQIASQXXXXXXXXXXXXXXXXXX-XASLHQVEIDLESV 268
++++ Q I + V L++ Q L+Q +L+ +
Sbjct: 1033 KMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEI 1092
Query: 269 R-VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXX 327
+QL+E+ + +L+++++ E + K
Sbjct: 1093 HEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGV--------KQDTTLNELQE 1144
Query: 328 XXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEE 387
A +N++ + +++L++ +E L +DL K+ LQ EQL +E+K EE
Sbjct: 1145 QLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ---EQL----VELKMLAEE 1197
Query: 388 TVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
+ + L+ E Q + +K+ + + + E KK+ ++L
Sbjct: 1198 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1244
Score = 46.8 bits (106), Expect = 2e-04
Identities = 81/422 (19%), Positives = 171/422 (40%), Gaps = 23/422 (5%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIERE--KADLSVQVIQLSERLEEAEGGAESQ 85
++ +A LE + Q E+ R+L+ ++ + + + + ++S + E + E
Sbjct: 439 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVV 498
Query: 86 FEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKE 145
+ + + ++ KL+KL E E+ L KK Q +FQEQ+ ++ K+++E
Sbjct: 499 DVMKKSSEEQIAKLQKLHEKELARKEQE---LTKKLQTREREFQEQM-KVALEKSQSEYL 554
Query: 146 KSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRL 205
K + E E LA E ++K ++++ +L +L + E I+++ S ++
Sbjct: 555 KISQEKEQQESLALEELELQKKAILTESENKLR----DLQQEAETYRTRILELESSLEKS 610
Query: 206 SQENIELVKEVQ---DLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
QEN K++ + + N N + Q +
Sbjct: 611 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 670
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRS------KFXXXXXXXXXXXXXXXX 316
++E +R + E+E E L + + +A+ E + ++ K
Sbjct: 671 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKA 730
Query: 317 KYSXXXXXXXXXXXTLIAKIN---NVEKQKSRLQSEVEVLIIDLEKA-NGTARELQKRTE 372
++ T K +++QK+ Q +V+ +I + E + T + L+ +
Sbjct: 731 RHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQIN 790
Query: 373 QLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGD 432
QLE + E L+E E + D++ + ELQ+ S +LD + + A + K +
Sbjct: 791 QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEE 850
Query: 433 DL 434
L
Sbjct: 851 QL 852
Score = 46.0 bits (104), Expect = 3e-04
Identities = 88/432 (20%), Positives = 170/432 (39%), Gaps = 39/432 (9%)
Query: 33 LSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKR 92
+ R E+ ++ ++ ++S +E + EK L Q L ERL+E E + K
Sbjct: 319 VKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQ---LDERLQELEKIKDLHMAEKTKL 375
Query: 93 DTELLKLRKLLED-------VHLESEETAHLLKKKNQEIVIDFQEQIDQLTK--TKARAE 143
T+L + L+E V E++ H + +E + + +I Q+T + R +
Sbjct: 376 ITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ 435
Query: 144 KEKSKFQA--EVYELLAQVENV----TKEKITISKTCERLEITISELHIKI-EELNRTIV 196
KEKS+ A E+ + L+ + K K + + + +E T E I + +EL+R
Sbjct: 436 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQ 495
Query: 197 DITSHKQRLSQENI---------ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXX 247
++ ++ S+E I EL ++ Q+L ++ +
Sbjct: 496 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK 555
Query: 248 XXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXX 307
SL E++L+ + E E++ R DL+++ I S
Sbjct: 556 ISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKSLQEN 614
Query: 308 XXXXXXXXXKYSXXXXXXXXXXXTLIAK----INNVEKQKSRLQSE-VEVLIIDLEKANG 362
++ K + +++ Q+ L +E ++VL +
Sbjct: 615 KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 674
Query: 363 TAREL--QKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQK 420
RE Q++ L+ I ++ +EE + E+T L KQTEL+ +S EL + + +
Sbjct: 675 KLREKCEQEKETLLKDKEIIFQAHIEE---MNEKTLEKLDVKQTELESLSSELSEVLKAR 731
Query: 421 DALARENKKMGD 432
L E + D
Sbjct: 732 HKLEEELSVLKD 743
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/255 (18%), Positives = 111/255 (43%), Gaps = 28/255 (10%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI------NR 90
E++ +Q ++E+ L++R++ DL + ++ E+ GA S +++ N
Sbjct: 300 EERAESLQQEVEA---LKERVDELTTDLEILKAEIEEK---GSDGAASSYQLKQLEEQNA 353
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ L+++R L E + L++KKNQE+ + Q+ + R ++E S+ +
Sbjct: 354 RLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ--------RERLQEELSQAE 405
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ + EL QV+ + + +R + + E K+ EL T+ D+ + +++ N
Sbjct: 406 STIDELKEQVDAALGAEEMVEMLTDR-NLNLEE---KVRELRETVGDL----EAMNEMND 457
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL + ++ ++ + + + + Q+ L+ V
Sbjct: 458 ELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNR 517
Query: 271 QLEEESEARLDLERQ 285
+L + EA ++ ++Q
Sbjct: 518 ELTNQQEASVERQQQ 532
Score = 45.6 bits (103), Expect = 4e-04
Identities = 77/371 (20%), Positives = 140/371 (37%), Gaps = 39/371 (10%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E+ L QV L E+LE + KR + KL++L + H E K
Sbjct: 200 KEEEGLRAQVRDLEEKLET----------LRLKRAEDKAKLKEL--EKHKIQLEQVQEWK 247
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
K QE D Q ++ + K A + K ++ E+ + +E T +K + E L+
Sbjct: 248 SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQ 307
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXX 238
+ L +++EL D+ K + ++ + LK E LK +
Sbjct: 308 QEVEALKERVDELT---TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 364
Query: 239 XXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-SEARLDLERQLVKANGEIGHWR 297
++E+ + R +L+EE S+A ++ + + +G
Sbjct: 365 LSSSEKQEHVKLQKLMEKKNQELEV-VRQQRERLQEELSQAESTIDELKEQVDAALG--- 420
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
+ + ++N+ E Q++ ++E+E L L
Sbjct: 421 ----AEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMND-ELQENARETELE-LREQL 474
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ A RE QKR E + ETV Y+QT + R LQ V+ EL T
Sbjct: 475 DMAGARVREAQKRVEAAQ-----------ETVADYQQTIKKYRQLTAHLQDVNREL--TN 521
Query: 418 EQKDALARENK 428
+Q+ ++ R+ +
Sbjct: 522 QQEASVERQQQ 532
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ + +LE R+ R+R++ E + + +L E+++ A GAE E+ R+
Sbjct: 375 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL-GAEEMVEMLTDRNL 433
Query: 95 EL-LKLRKLLEDV-HLES-EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
L K+R+L E V LE+ E L++ +E ++ +EQ+D A+K Q
Sbjct: 434 NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQE 493
Query: 152 EV 153
V
Sbjct: 494 TV 495
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 47.6 bits (108), Expect = 1e-04
Identities = 78/430 (18%), Positives = 167/430 (38%), Gaps = 21/430 (4%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ-FE 87
+L L +ED+ R ++ L +EL ++ ++ L ++ E LE+ G + + +
Sbjct: 1782 NLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIE-LEKIVGELKKENSD 1840
Query: 88 INRKRDTELLKLRKLLEDVH----LESEETAHLLKKKNQEI------VID-FQEQIDQLT 136
++ K + ++LL+ V L S+ H K ++I V D ++E+ +
Sbjct: 1841 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVE 1900
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITI----SELHIKIEELN 192
+R EK+ + E L A +E V EK+ + K E + I EL + E N
Sbjct: 1901 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN 1960
Query: 193 --RTIVDITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
R +D S K + E +KE Q+L+ + ++ ++
Sbjct: 1961 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2020
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
++ L+S+ + S + +LE Q+ + N E K
Sbjct: 2021 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE-KELLVKESESLQARLS 2079
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
S ++++ +++ +L+ +E L + +E + +
Sbjct: 2080 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2139
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ ++ ER N +K ++E + + ++ + + + E++ + Q + +AR K
Sbjct: 2140 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV 2199
Query: 430 MGDDLHDARA 439
DL R+
Sbjct: 2200 FELDLVTLRS 2209
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/254 (19%), Positives = 105/254 (41%), Gaps = 10/254 (3%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I++ + +++ + EL Q + + ++L L E+L+ E +++ + + ++ +L
Sbjct: 2001 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL 2060
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
K E + ESE L + + E ++ + ++ K S Q EV++L
Sbjct: 2061 NKEKELLVKESESLQARLSESDYE-KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRG 2119
Query: 160 VENV-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+E + K+++ I++ + E L K+E L R + ++ Q L + E
Sbjct: 2120 IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL-QMSEENQELVILDAEN 2178
Query: 213 VK-EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
K EV+ LK IE + L +++ L S +
Sbjct: 2179 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSL 2238
Query: 272 LEEESEARLDLERQ 285
LEE+ +A + ++ +
Sbjct: 2239 LEEKEQAEIQIKEE 2252
Score = 40.7 bits (91), Expect = 0.012
Identities = 72/415 (17%), Positives = 165/415 (39%), Gaps = 18/415 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A++ + + ++Q+ L+ E + ++ + L +EE S +
Sbjct: 2245 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2304
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + + + K +L+ + ESE A LLK + + + + + +I + + A E E S
Sbjct: 2305 LRARLEADEKKQLCVLQQLK-ESEHHADLLKGRVENL--ERELEIARTNQEHAALEAENS 2361
Query: 148 KFQAEVYELLAQVENVTK-----EKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
K EV L A++E +T+ E ++ E+ +T +EL + E ++ + +S +
Sbjct: 2362 K--GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT-NELQKEQERISELEIINSSFE 2418
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
L ++ E V+ + +E + ++ + + + +E
Sbjct: 2419 NILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLE 2478
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
++ + L+E + L+ + E+ + K +
Sbjct: 2479 LEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVS 2538
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN--GTARELQKRTEQLERVNIE 380
+ K N+E + ++ E ++ ++ + A+ T LQ + LE E
Sbjct: 2539 KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN---E 2595
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALARENKKMGDDL 434
++ + + E+ + + K+TELQR HE+ KT E ++ L+ E ++ +L
Sbjct: 2596 LELTKMDKMSFVEKVNK-MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2649
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/175 (23%), Positives = 84/175 (48%), Gaps = 10/175 (5%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREK 61
S +A+TS+ + + N+ + LSAL E +++L+ D +E+E+ Q +++
Sbjct: 875 SFVAETSQRISKLQEDTSAHQNV-VAETLSALENKEKELQLLNDKVETEQAEIQELKKSN 933
Query: 62 ADL--SVQVIQL-SERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLL 117
L S++ +QL SE L + S +N++ EL + L++++ ++E +L+
Sbjct: 934 HLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLI 993
Query: 118 KKKNQ-EIVIDFQEQIDQLTKTKARAEK----EKSKFQAEVYELLAQVENVTKEK 167
+K ID +E+ + + EK ++ + YE L+Q +EK
Sbjct: 994 QKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK 1048
Score = 35.1 bits (77), Expect = 0.59
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
K + LQ+ V+ L LE +LQK+ E+L ++ EI+ L + Q+++ +
Sbjct: 822 KNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETS 881
Query: 401 NKQTELQR-VSHELDKTREQKDALARENKKM 430
+ ++LQ S + E AL + K++
Sbjct: 882 QRISKLQEDTSAHQNVVAETLSALENKEKEL 912
Score = 35.1 bits (77), Expect = 0.59
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E QRI + + D S ++E L E + +N K +TE ++++L + HL +
Sbjct: 879 ETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLED 938
Query: 112 ---------ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
ET L KK+ I+ + +I++LT+ ++ + E L+ + E+
Sbjct: 939 SLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSES 998
Query: 163 ----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + + +IS+ ++ + L + EE D+ S K + +QE
Sbjct: 999 FANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDL-SQKYKAAQE 1047
Score = 35.1 bits (77), Expect = 0.59
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ EK+K LQ E++ + DLE +N + Q+ L+ I+ + +
Sbjct: 1222 KLQESEKEKECLQHELQTIRGDLETSNLQDMQSQE-ISGLKDCEIDAEEKYISGPHELST 1280
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+Q D + Q LQ ++L++ + + L E ++ +L+D+R+
Sbjct: 1281 SQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRS 1325
Score = 34.3 bits (75), Expect = 1.0
Identities = 41/203 (20%), Positives = 92/203 (45%), Gaps = 11/203 (5%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT---ELLKLR 100
+D +E E ++R+ I + L + L + E + + R++ T E L +
Sbjct: 2682 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2741
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
KL D+ S+E + K +I+ + ++ ++D L K + +KE + Q ++ L+
Sbjct: 2742 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL-KYVNQLKKENERAQGKMKLLIKS 2800
Query: 160 VENVTKEKITISKTCERLEI------TISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
+ + +EK + K +L+ T + + K++EL I ++ + ++E E +
Sbjct: 2801 CKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYL 2860
Query: 214 KEVQDLKVNIENVVYLKSQIASQ 236
+ L ++ E + K + +Q
Sbjct: 2861 DKYCSLLISHEKLEKAKEMLETQ 2883
Score = 32.3 bits (70), Expect = 4.2
Identities = 22/105 (20%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
++ ++ Q L++++ L + L+ G +E++ + + + + ++++ + V+L E+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQ---GHEKEMKGQVNKFQELQLQLE---KAKVELIEK- 332
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
++ L + EL R + + D+ + AL ++ KK+ +DL R N
Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQN 377
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 47.6 bits (108), Expect = 1e-04
Identities = 78/430 (18%), Positives = 167/430 (38%), Gaps = 21/430 (4%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ-FE 87
+L L +ED+ R ++ L +EL ++ ++ L ++ E LE+ G + + +
Sbjct: 1879 NLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIE-LEKIVGELKKENSD 1937
Query: 88 INRKRDTELLKLRKLLEDVH----LESEETAHLLKKKNQEI------VID-FQEQIDQLT 136
++ K + ++LL+ V L S+ H K ++I V D ++E+ +
Sbjct: 1938 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVE 1997
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITI----SELHIKIEELN 192
+R EK+ + E L A +E V EK+ + K E + I EL + E N
Sbjct: 1998 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN 2057
Query: 193 --RTIVDITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
R +D S K + E +KE Q+L+ + ++ ++
Sbjct: 2058 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2117
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
++ L+S+ + S + +LE Q+ + N E K
Sbjct: 2118 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE-KELLVKESESLQARLS 2176
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
S ++++ +++ +L+ +E L + +E + +
Sbjct: 2177 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2236
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ ++ ER N +K ++E + + ++ + + + E++ + Q + +AR K
Sbjct: 2237 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV 2296
Query: 430 MGDDLHDARA 439
DL R+
Sbjct: 2297 FELDLVTLRS 2306
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/254 (19%), Positives = 105/254 (41%), Gaps = 10/254 (3%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I++ + +++ + EL Q + + ++L L E+L+ E +++ + + ++ +L
Sbjct: 2098 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL 2157
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
K E + ESE L + + E ++ + ++ K S Q EV++L
Sbjct: 2158 NKEKELLVKESESLQARLSESDYE-KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRG 2216
Query: 160 VENV-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+E + K+++ I++ + E L K+E L R + ++ Q L + E
Sbjct: 2217 IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL-QMSEENQELVILDAEN 2275
Query: 213 VK-EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
K EV+ LK IE + L +++ L S +
Sbjct: 2276 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSL 2335
Query: 272 LEEESEARLDLERQ 285
LEE+ +A + ++ +
Sbjct: 2336 LEEKEQAEIQIKEE 2349
Score = 41.5 bits (93), Expect = 0.007
Identities = 72/415 (17%), Positives = 166/415 (40%), Gaps = 18/415 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A++ + + ++Q+ L+ E + ++ + L +EE S +
Sbjct: 2342 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2401
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + + + K +L+ + ESE A LLK + + + + + +I + + A E E S
Sbjct: 2402 LRARLEADEKKQLCVLQQLK-ESEHHADLLKGRVENL--ERELEIARTNQEHAALEAENS 2458
Query: 148 KFQAEVYELLAQVENVTK-----EKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
K EV L A++E +T+ E ++ E+ ++T +EL + E ++ + +S +
Sbjct: 2459 K--GEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLT-NELQKEQERISELEIINSSFE 2515
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
L ++ E V+ + +E + ++ + + + +E
Sbjct: 2516 NILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLE 2575
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
++ + L+E + L+ + E+ + K +
Sbjct: 2576 LEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVS 2635
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN--GTARELQKRTEQLERVNIE 380
+ K N+E + ++ E ++ ++ + A+ T LQ + LE E
Sbjct: 2636 KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN---E 2692
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALARENKKMGDDL 434
++ + + E+ + + K+TELQR HE+ KT E ++ L+ E ++ +L
Sbjct: 2693 LELTKMDKMSFVEKVNK-MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2746
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/175 (23%), Positives = 84/175 (48%), Gaps = 10/175 (5%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREK 61
S +A+TS+ + + N+ + LSAL E +++L+ D +E+E+ Q +++
Sbjct: 876 SFVAETSQRISKLQEDTSAHQNV-VAETLSALENKEKELQLLNDKVETEQAEIQELKKSN 934
Query: 62 ADL--SVQVIQ-LSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLL 117
L S++ +Q LSE L + S +N++ EL + L++++ ++E +L+
Sbjct: 935 HLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLI 994
Query: 118 KKKNQ-EIVIDFQEQIDQLTKTKARAEK----EKSKFQAEVYELLAQVENVTKEK 167
+K ID +E+ + + EK ++ + YE L+Q +EK
Sbjct: 995 QKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK 1049
Score = 35.1 bits (77), Expect = 0.59
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
K + LQ+ V+ L LE +LQK+ E+L ++ EI+ L + Q+++ +
Sbjct: 823 KNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETS 882
Query: 401 NKQTELQR-VSHELDKTREQKDALARENKKM 430
+ ++LQ S + E AL + K++
Sbjct: 883 QRISKLQEDTSAHQNVVAETLSALENKEKEL 913
Score = 35.1 bits (77), Expect = 0.59
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E QRI + + D S ++E L E + +N K +TE ++++L + HL +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLED 939
Query: 112 ---------ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
ET L KK+ I+ + +I++LT+ ++ + E L+ + E+
Sbjct: 940 SLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSES 999
Query: 163 ----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + + +IS+ ++ + L + EE D+ S K + +QE
Sbjct: 1000 FANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDL-SQKYKAAQE 1048
Score = 35.1 bits (77), Expect = 0.59
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ EK+K LQ E++ + DLE +N + Q+ L+ I+ + +
Sbjct: 1223 KLQESEKEKECLQHELQTIRGDLETSNLQDMQSQE-ISGLKDCEIDAEEKYISGPHELST 1281
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+Q D + Q LQ ++L++ + + L E ++ +L+D+R+
Sbjct: 1282 SQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRS 1326
Score = 34.7 bits (76), Expect = 0.79
Identities = 39/202 (19%), Positives = 94/202 (46%), Gaps = 12/202 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKA----DLSVQVIQLSERLEEAEGGAESQFEINRKR 92
E+++R ++++ E L + +KA L ++ + + L +++ AE N +
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQ 533
Query: 93 DTELLKLRKLL--EDVHLESEE----TAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEK 144
+T L L++ + ++ L E+ A L K+++ Q+++ + I+QL ++ EK
Sbjct: 534 ETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E + + + E + +EK S E ++++ + E L I + + +
Sbjct: 594 ESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKT 653
Query: 205 LSQENIELVKEVQDLKVNIENV 226
++ E + V+ L+++ EN+
Sbjct: 654 QQIKSHEYNERVRTLEMDRENL 675
Score = 34.3 bits (75), Expect = 1.0
Identities = 41/203 (20%), Positives = 92/203 (45%), Gaps = 11/203 (5%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT---ELLKLR 100
+D +E E ++R+ I + L + L + E + + R++ T E L +
Sbjct: 2779 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2838
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
KL D+ S+E + K +I+ + ++ ++D L K + +KE + Q ++ L+
Sbjct: 2839 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL-KYVNQLKKENERAQGKMKLLIKS 2897
Query: 160 VENVTKEKITISKTCERLEI------TISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
+ + +EK + K +L+ T + + K++EL I ++ + ++E E +
Sbjct: 2898 CKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYL 2957
Query: 214 KEVQDLKVNIENVVYLKSQIASQ 236
+ L ++ E + K + +Q
Sbjct: 2958 DKYCSLLISHEKLEKAKEMLETQ 2980
Score = 32.3 bits (70), Expect = 4.2
Identities = 22/105 (20%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
++ ++ Q L++++ L + L+ G +E++ + + + + ++++ + V+L E+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQ---GHEKEMKGQVNKFQELQLQLE---KAKVELIEK- 332
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
++ L + EL R + + D+ + AL ++ KK+ +DL R N
Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQN 377
>S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 330
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 91 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLER 150
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 151 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 210
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 211 EILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRE 264
Score = 38.3 bits (85), Expect = 0.064
Identities = 28/147 (19%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
RK ++ ++ LED +E K+N++ + + QL + A AE+ + +
Sbjct: 6 RKLQAQMKDFQRELEDARASRDEI-FATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 64
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
E EL ++ + + + RLE I++L ++EE + ++ ++ +Q+
Sbjct: 65 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 124
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQ 236
+L E+ + + + Q+ Q
Sbjct: 125 EQLSNELATERTTAQKNESARQQLERQ 151
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/110 (20%), Positives = 52/110 (47%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L AKI +E+Q + E + L++ + +E+ + E ++ + K + E+
Sbjct: 177 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAG 236
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 237 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 286
Score = 35.5 bits (78), Expect = 0.45
Identities = 42/236 (17%), Positives = 96/236 (40%), Gaps = 12/236 (5%)
Query: 64 LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE 123
L Q+ LE+A + F ++ + K K LE ++ +E ++ ++
Sbjct: 8 LQAQMKDFQRELEDARASRDEIFATAKENE----KKAKSLEADLMQLQEDLAAAERARKQ 63
Query: 124 IVIDFQEQIDQLTKT---KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEIT 180
++ +E ++L + + + EK + +A + +L ++E +S +
Sbjct: 64 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 123
Query: 181 ISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXX 240
+L ++ T S +Q+L ++N EL ++ +++ +++ KS IA+
Sbjct: 124 AEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSK--FKSTIAALEAKI 181
Query: 241 XXXXXXXXXXXXXXXA---SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
A SL Q + L+ + +Q+E+E + + Q K N +
Sbjct: 182 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGV 237
Score = 35.5 bits (78), Expect = 0.45
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLY 392
N ++ +K RL++ + L +LE+ G + ++K T+Q E+++ E+ + T Q
Sbjct: 83 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE-RTTAQKN 141
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQK 420
E ++ L + EL+ HE++ + K
Sbjct: 142 ESARQQLERQNKELRSKLHEMEGAVKSK 169
Score = 33.5 bits (73), Expect = 1.8
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 9/154 (5%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+ + + E E L +L + LQ +LE +++ LEE E +
Sbjct: 58 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 117
Query: 400 RNKQTELQRVSHEL--DKTREQKDA-----LARENKKMGDDLHDARANITXXXXXXXXXX 452
R + +++S+EL ++T QK+ L R+NK++ LH+ +
Sbjct: 118 RKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 177
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 178 EAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 209
Score = 31.5 bits (68), Expect = 7.3
Identities = 24/98 (24%), Positives = 46/98 (46%)
Query: 25 EYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAES 84
E A +L + + K++ I +E ER++ ++ + + + V QL +LEEAE ++
Sbjct: 194 EKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQR 253
Query: 85 QFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQ 122
RK EL + + E + E L++ N+
Sbjct: 254 INANRRKLQRELDEATESNEAMGREVNALKSKLRRGNE 291
Score = 31.1 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 172 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 231
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 232 KGNAGVKQLKRQLEEAEEESQRINANRRKLQREL 265
>S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 296
Score = 47.6 bits (108), Expect = 1e-04
Identities = 35/174 (20%), Positives = 76/174 (43%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
RLE +I ++++LE E+ + + + Q QLS L A+ ++ +
Sbjct: 91 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERTTAQKNESARQQLER 150
Query: 95 ELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVY 154
+ +LR L ++ + + + +EQ++Q + K A K + ++
Sbjct: 151 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 210
Query: 155 ELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
E+L QVE+ K + E+ + +L ++EE I +++++L +E
Sbjct: 211 EILLQVEDERKMAEQYKEQAEKGNAGVKQLKRQLEEAEEESQRINANRRKLQRE 264
Score = 38.3 bits (85), Expect = 0.064
Identities = 28/147 (19%), Positives = 64/147 (43%), Gaps = 1/147 (0%)
Query: 90 RKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKF 149
RK ++ ++ LED +E K+N++ + + QL + A AE+ + +
Sbjct: 6 RKLQAQMKDFQRELEDARASRDEI-FATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 64
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQEN 209
E EL ++ + + + RLE I++L ++EE + ++ ++ +Q+
Sbjct: 65 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 124
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQ 236
+L E+ + + + Q+ Q
Sbjct: 125 EQLSNELATERTTAQKNESARQQLERQ 151
Score = 37.5 bits (83), Expect = 0.11
Identities = 23/110 (20%), Positives = 52/110 (47%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L AKI +E+Q + E + L++ + +E+ + E ++ + K + E+
Sbjct: 177 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAG 236
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+Q +R L + E QR++ K + + D N+ MG +++ ++ +
Sbjct: 237 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 286
Score = 35.5 bits (78), Expect = 0.45
Identities = 42/236 (17%), Positives = 96/236 (40%), Gaps = 12/236 (5%)
Query: 64 LSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQE 123
L Q+ LE+A + F ++ + K K LE ++ +E ++ ++
Sbjct: 8 LQAQMKDFQRELEDARASRDEIFATAKENE----KKAKSLEADLMQLQEDLAAAERARKQ 63
Query: 124 IVIDFQEQIDQLTKT---KARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEIT 180
++ +E ++L + + + EK + +A + +L ++E +S +
Sbjct: 64 ADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQ 123
Query: 181 ISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXX 240
+L ++ T S +Q+L ++N EL ++ +++ +++ KS IA+
Sbjct: 124 AEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSK--FKSTIAALEAKI 181
Query: 241 XXXXXXXXXXXXXXXA---SLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEI 293
A SL Q + L+ + +Q+E+E + + Q K N +
Sbjct: 182 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAGV 237
Score = 35.5 bits (78), Expect = 0.45
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 337 NNVEKQKSRLQSEVEVLIIDLEKANGT----ARELQKRTEQLERVNIEIKSRLEETVQLY 392
N ++ +K RL++ + L +LE+ G + ++K T+Q E+++ E+ + T Q
Sbjct: 83 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATE-RTTAQKN 141
Query: 393 EQTQRDLRNKQTELQRVSHELDKTREQK 420
E ++ L + EL+ HE++ + K
Sbjct: 142 ESARQQLERQNKELRSKLHEMEGAVKSK 169
Score = 33.5 bits (73), Expect = 1.8
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 9/154 (5%)
Query: 340 EKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDL 399
E+ + + E E L +L + LQ +LE +++ LEE E +
Sbjct: 58 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 117
Query: 400 RNKQTELQRVSHEL--DKTREQKDA-----LARENKKMGDDLHDARANITXXXXXXXXXX 452
R + +++S+EL ++T QK+ L R+NK++ LH+ +
Sbjct: 118 RKATQQAEQLSNELATERTTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 177
Query: 453 XXXXXXXXXXXXXTAAYKEAEAGRKAEEQRSQRL 486
A +E +A K+ +Q+ ++L
Sbjct: 178 EAKIAQLEEQVEQEA--REKQAATKSLKQKDKKL 209
Score = 31.1 bits (67), Expect = 9.7
Identities = 20/94 (21%), Positives = 45/94 (47%)
Query: 31 SALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINR 90
S ++ LE KI +++ +E E +Q + ++ ++ ++E+ AE E
Sbjct: 172 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 231
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEI 124
K + + +L++ LE+ ES+ +K +E+
Sbjct: 232 KGNAGVKQLKRQLEEAEEESQRINANRRKLQREL 265
>BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/205 (20%), Positives = 101/205 (49%), Gaps = 20/205 (9%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELL 97
+K R ++D + R+ + IER+ +L ++ + E E+ AE Q +I ++ EL
Sbjct: 251 EKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLS--AERQEQIKQRTKLEL- 307
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELL 157
K + L +++ SE+ LLK++ Q+++ +E+ +L +T+ + K K + + L
Sbjct: 308 KAKDLQDELAGNSEQRKRLLKER-QKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLA 366
Query: 158 AQVENVT--------------KEKIT--ISKTCERLEITISELHIKIEELNRTIVDITSH 201
+ T KE+ I K + L+ I++ +I +++ + D ++
Sbjct: 367 QATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEAN 426
Query: 202 KQRLSQENIELVKEVQDLKVNIENV 226
K++ ++ +L +++ ++K +E +
Sbjct: 427 KEKNLEQYNKLDQDLNEVKARVEEL 451
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 9/194 (4%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
++ E + ++LE K + +QD+L E R+R+ +E+ L ++ + + L E E
Sbjct: 291 LSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPK 350
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
S E + L + + D++ + + K+ ++ + I + K+ +
Sbjct: 351 FNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERD------KWIKKELKSLDQ 404
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A +K + A +++ L E KEK + +L+ ++E+ ++EEL+R ++ +
Sbjct: 405 AINDKKRQIAAIHKDLEDTE-ANKEKNL--EQYNKLDQDLNEVKARVEELDRKYYEVKNK 461
Query: 202 KQRLSQENIELVKE 215
K L E L +E
Sbjct: 462 KDELQSERNYLWRE 475
Score = 36.3 bits (80), Expect = 0.26
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
DT +L +L +DV EE L K N+ + + +IDQL + E ++ KF
Sbjct: 670 DTRKSRL-ELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKF 728
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH--KQRLSQ 207
+A +L++++ + +++ KT + ++ L + + T + + LSQ
Sbjct: 729 KASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQ 788
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQ 236
++E K V L I + Q+ ++
Sbjct: 789 LSLEDQKRVDALNDEIRQLQQENRQLLNE 817
>AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 617
Score = 47.6 bits (108), Expect = 1e-04
Identities = 65/346 (18%), Positives = 143/346 (41%), Gaps = 27/346 (7%)
Query: 104 EDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSK----FQAEVYELLAQ 159
+D+ E E LK++ QE + QI + + K RA E ++ ++A++ EL
Sbjct: 6 DDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGK-RALSELTQGVTCYKAKIKELETI 64
Query: 160 VENVTKEKITISKTCERL---EITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEV 216
+E E+ +K + + E I +L ++E + D + + L+ + ++L +E+
Sbjct: 65 LETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEI 124
Query: 217 QDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEES 276
L N++++ +L + A ++ DL+ +
Sbjct: 125 TQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLK 184
Query: 277 EARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKI 336
E D ++Q+ + E+ R + K + L K
Sbjct: 185 EKLTDAKKQIKQVQKEVSVMRDE-----------DKLLRIKINELEKKKNQCSQELDMKQ 233
Query: 337 NNVEKQKSRLQSE-VEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
+++ K +L ++ VE I E+A ++L + + +E +++ LEE Q +
Sbjct: 234 RTIQQLKEQLNNQKVEEAIQQYERA---CKDLNVKEKIIE----DMRMTLEEQEQTQVEQ 286
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARANI 441
+ L K E++R++ EL+K +E+ + L +N + + H+ ++
Sbjct: 287 DQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDV 332
Score = 46.0 bits (104), Expect = 3e-04
Identities = 78/395 (19%), Positives = 162/395 (41%), Gaps = 41/395 (10%)
Query: 39 KIRLIQDDLES---ERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
KI+ ++ LE+ ER ++E++ + +++L L+E + + + + + +
Sbjct: 57 KIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 116
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQ---IDQLTKTKARAEKEKSKFQAE 152
LKL++ + + ++ HLL+ K +E + QE ++L+ + AR + K+ Q +
Sbjct: 117 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 176
Query: 153 VYELLAQVENVTKEKITISKTCERLEITISE---LHIKIEELNRTIVDITSHKQRLSQEN 209
+ E +T K I + + + + E L IKI EL + K + SQE
Sbjct: 177 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEK-------KKNQCSQEL 229
Query: 210 IELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVR 269
+ +Q LK + N K + A Q L+ E +E +R
Sbjct: 230 DMKQRTIQQLKEQLNN---QKVEEAIQ-------------QYERACKDLNVKEKIIEDMR 273
Query: 270 VQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXX 329
+ LEE+ + +++ ++ L E+ + K +
Sbjct: 274 MTLEEQEQTQVEQDQVLEAKLEEV----ERLATELEKWKEKCNDLETKNNQRSNKEHENN 329
Query: 330 XTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERV-NIEIKSRLEET 388
++ K+ N++ + LQ + D +K L + ++ E + N E+K E+
Sbjct: 330 TDVLGKLTNLQDE---LQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDR 386
Query: 389 VQLYEQTQRDLRNKQTELQRVSHELDKTREQKDAL 423
+ ++Q Q ++ +L +L K RE++D L
Sbjct: 387 ERFFKQ-QNEMEILTAQLTEKDSDLQKWREERDQL 420
Score = 38.7 bits (86), Expect = 0.048
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)
Query: 19 TTDVNIE---YSADLSALSR-LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSER 74
T D+N++ +++ L+ L+D L+Q E E RQ E+ K +LS +
Sbjct: 110 TKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNL 169
Query: 75 LEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETA-------HLLKKKNQ-EIVI 126
+ + E ++ K +++++ ++V + +E L KKKNQ +
Sbjct: 170 KADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQEL 229
Query: 127 DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKI--TISKTCERLEITISE- 183
D +++ Q K + +K + Q YE + NV KEKI + T E E T E
Sbjct: 230 DMKQRTIQQLKEQLNNQKVEEAIQQ--YERACKDLNV-KEKIIEDMRMTLEEQEQTQVEQ 286
Query: 184 ---LHIKIEELNRTIVDITSHKQR 204
L K+EE+ R ++ K++
Sbjct: 287 DQVLEAKLEEVERLATELEKWKEK 310
Score = 33.5 bits (73), Expect = 1.8
Identities = 46/210 (21%), Positives = 96/210 (45%), Gaps = 19/210 (9%)
Query: 40 IRLIQDDLESER--ELRQRIEREKADLSVQ---VIQLSERLEEAEGGA-------ESQFE 87
I+ +++ L +++ E Q+ ER DL+V+ + + LEE E E++ E
Sbjct: 236 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 295
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ TEL K ++ D+ ++ + ++ + N +++ D+L +++ + ++
Sbjct: 296 EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRK 355
Query: 148 KFQAEVYELLAQ---VENV-TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQ 203
K+ E L+ Q EN+ KE ++ ER +E+ I +L D+ K
Sbjct: 356 KWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQLTEKDSDL--QKW 413
Query: 204 RLSQENIELVKEVQDLKVNIENVVYLKSQI 233
R ++ + E+Q LK I + V ++I
Sbjct: 414 REERDQLVAALEIQ-LKALISSNVQKDNEI 442
Score = 31.9 bits (69), Expect = 5.5
Identities = 33/184 (17%), Positives = 84/184 (45%), Gaps = 8/184 (4%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLL 103
Q +E ++ L ++E E L+ ++ + E+ + E + + +T++L L
Sbjct: 281 QTQVEQDQVLEAKLE-EVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNL 339
Query: 104 EDVHLESEETAHLLKKKNQE----IVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
+D ESE+ + +KK E ++ +E + K + +++ +F + E+
Sbjct: 340 QDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEIL 399
Query: 160 VENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQ---ENIELVKEV 216
+T++ + K E + ++ L I+++ L + V + ++L + E ++ ++
Sbjct: 400 TAQLTEKDSDLQKWREERDQLVAALEIQLKALISSNVQKDNEIEQLKRIISETSKIETQI 459
Query: 217 QDLK 220
D+K
Sbjct: 460 MDIK 463
>AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 47.6 bits (108), Expect = 1e-04
Identities = 78/430 (18%), Positives = 167/430 (38%), Gaps = 21/430 (4%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ-FE 87
+L L +ED+ R ++ L +EL ++ ++ L ++ E LE+ G + + +
Sbjct: 1783 NLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIE-LEKIVGELKKENSD 1841
Query: 88 INRKRDTELLKLRKLLEDVH----LESEETAHLLKKKNQEI------VID-FQEQIDQLT 136
++ K + ++LL+ V L S+ H K ++I V D ++E+ +
Sbjct: 1842 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVE 1901
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITI----SELHIKIEELN 192
+R EK+ + E L A +E V EK+ + K E + I EL + E N
Sbjct: 1902 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN 1961
Query: 193 --RTIVDITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
R +D S K + E +KE Q+L+ + ++ ++
Sbjct: 1962 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
++ L+S+ + S + +LE Q+ + N E K
Sbjct: 2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE-KELLVKESESLQARLS 2080
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
S ++++ +++ +L+ +E L + +E + +
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2140
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ ++ ER N +K ++E + + ++ + + + E++ + Q + +AR K
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV 2200
Query: 430 MGDDLHDARA 439
DL R+
Sbjct: 2201 FELDLVTLRS 2210
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/254 (19%), Positives = 105/254 (41%), Gaps = 10/254 (3%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I++ + +++ + EL Q + + ++L L E+L+ E +++ + + ++ +L
Sbjct: 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL 2061
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
K E + ESE L + + E ++ + ++ K S Q EV++L
Sbjct: 2062 NKEKELLVKESESLQARLSESDYE-KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRG 2120
Query: 160 VENV-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+E + K+++ I++ + E L K+E L R + ++ Q L + E
Sbjct: 2121 IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL-QMSEENQELVILDAEN 2179
Query: 213 VK-EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
K EV+ LK IE + L +++ L S +
Sbjct: 2180 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSL 2239
Query: 272 LEEESEARLDLERQ 285
LEE+ +A + ++ +
Sbjct: 2240 LEEKEQAEIQIKEE 2253
Score = 40.7 bits (91), Expect = 0.012
Identities = 72/415 (17%), Positives = 165/415 (39%), Gaps = 18/415 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A++ + + ++Q+ L+ E + ++ + L +EE S +
Sbjct: 2246 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2305
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + + + K +L+ + ESE A LLK + + + + + +I + + A E E S
Sbjct: 2306 LRARLEADEKKQLCVLQQLK-ESEHHADLLKGRVENL--ERELEIARTNQEHAALEAENS 2362
Query: 148 KFQAEVYELLAQVENVTK-----EKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
K EV L A++E +T+ E ++ E+ +T +EL + E ++ + +S +
Sbjct: 2363 K--GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT-NELQKEQERISELEIINSSFE 2419
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
L ++ E V+ + +E + ++ + + + +E
Sbjct: 2420 NILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLE 2479
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
++ + L+E + L+ + E+ + K +
Sbjct: 2480 LEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVS 2539
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN--GTARELQKRTEQLERVNIE 380
+ K N+E + ++ E ++ ++ + A+ T LQ + LE E
Sbjct: 2540 KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN---E 2596
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALARENKKMGDDL 434
++ + + E+ + + K+TELQR HE+ KT E ++ L+ E ++ +L
Sbjct: 2597 LELTKMDKMSFVEKVNK-MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2650
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/175 (23%), Positives = 84/175 (48%), Gaps = 10/175 (5%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREK 61
S +A+TS+ + + N+ + LSAL E +++L+ D +E+E+ Q +++
Sbjct: 876 SFVAETSQRISKLQEDTSAHQNV-VAETLSALENKEKELQLLNDKVETEQAEIQELKKSN 934
Query: 62 ADL--SVQVIQL-SERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLL 117
L S++ +QL SE L + S +N++ EL + L++++ ++E +L+
Sbjct: 935 HLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLI 994
Query: 118 KKKNQ-EIVIDFQEQIDQLTKTKARAEK----EKSKFQAEVYELLAQVENVTKEK 167
+K ID +E+ + + EK ++ + YE L+Q +EK
Sbjct: 995 QKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK 1049
Score = 35.1 bits (77), Expect = 0.59
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
K + LQ+ V+ L LE +LQK+ E+L ++ EI+ L + Q+++ +
Sbjct: 823 KNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETS 882
Query: 401 NKQTELQR-VSHELDKTREQKDALARENKKM 430
+ ++LQ S + E AL + K++
Sbjct: 883 QRISKLQEDTSAHQNVVAETLSALENKEKEL 913
Score = 35.1 bits (77), Expect = 0.59
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E QRI + + D S ++E L E + +N K +TE ++++L + HL +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLED 939
Query: 112 ---------ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
ET L KK+ I+ + +I++LT+ ++ + E L+ + E+
Sbjct: 940 SLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSES 999
Query: 163 ----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + + +IS+ ++ + L + EE D+ S K + +QE
Sbjct: 1000 FANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDL-SQKYKAAQE 1048
Score = 35.1 bits (77), Expect = 0.59
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ EK+K LQ E++ + DLE +N + Q+ L+ I+ + +
Sbjct: 1223 KLQESEKEKECLQHELQTIRGDLETSNLQDMQSQE-ISGLKDCEIDAEEKYISGPHELST 1281
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+Q D + Q LQ ++L++ + + L E ++ +L+D+R+
Sbjct: 1282 SQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRS 1326
Score = 34.7 bits (76), Expect = 0.79
Identities = 39/202 (19%), Positives = 94/202 (46%), Gaps = 12/202 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKA----DLSVQVIQLSERLEEAEGGAESQFEINRKR 92
E+++R ++++ E L + +KA L ++ + + L +++ AE N +
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQ 533
Query: 93 DTELLKLRKLL--EDVHLESEE----TAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEK 144
+T L L++ + ++ L E+ A L K+++ Q+++ + I+QL ++ EK
Sbjct: 534 ETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E + + + E + +EK S E ++++ + E L I + + +
Sbjct: 594 ESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKT 653
Query: 205 LSQENIELVKEVQDLKVNIENV 226
++ E + V+ L+++ EN+
Sbjct: 654 QQIKSHEYNERVRTLEMDRENL 675
Score = 34.3 bits (75), Expect = 1.0
Identities = 41/203 (20%), Positives = 92/203 (45%), Gaps = 11/203 (5%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT---ELLKLR 100
+D +E E ++R+ I + L + L + E + + R++ T E L +
Sbjct: 2683 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2742
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
KL D+ S+E + K +I+ + ++ ++D L K + +KE + Q ++ L+
Sbjct: 2743 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL-KYVNQLKKENERAQGKMKLLIKS 2801
Query: 160 VENVTKEKITISKTCERLEI------TISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
+ + +EK + K +L+ T + + K++EL I ++ + ++E E +
Sbjct: 2802 CKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYL 2861
Query: 214 KEVQDLKVNIENVVYLKSQIASQ 236
+ L ++ E + K + +Q
Sbjct: 2862 DKYCSLLISHEKLEKAKEMLETQ 2884
Score = 32.3 bits (70), Expect = 4.2
Identities = 22/105 (20%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
++ ++ Q L++++ L + L+ G +E++ + + + + ++++ + V+L E+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQ---GHEKEMKGQVNKFQELQLQLE---KAKVELIEK- 332
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
++ L + EL R + + D+ + AL ++ KK+ +DL R N
Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQN 377
Score = 31.5 bits (68), Expect = 7.3
Identities = 19/103 (18%), Positives = 50/103 (48%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L +++ ++K+K + Q +++ L L+K + L+R N + E +
Sbjct: 23 LEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKT 82
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ +L+ K++++ +L+ ++Q + L +E K+ +L
Sbjct: 83 KQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSEL 125
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 47.6 bits (108), Expect = 1e-04
Identities = 78/430 (18%), Positives = 167/430 (38%), Gaps = 21/430 (4%)
Query: 29 DLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQ-FE 87
+L L +ED+ R ++ L +EL ++ ++ L ++ E LE+ G + + +
Sbjct: 1783 NLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIE-LEKIVGELKKENSD 1841
Query: 88 INRKRDTELLKLRKLLEDVH----LESEETAHLLKKKNQEI------VID-FQEQIDQLT 136
++ K + ++LL+ V L S+ H K ++I V D ++E+ +
Sbjct: 1842 LSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVE 1901
Query: 137 KTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITI----SELHIKIEELN 192
+R EK+ + E L A +E V EK+ + K E + I EL + E N
Sbjct: 1902 NELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERN 1961
Query: 193 --RTIVDITSHKQRLSQENIELVKE-VQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXX 249
R +D S K + E +KE Q+L+ + ++ ++
Sbjct: 1962 QLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSS 2021
Query: 250 XXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXX 309
++ L+S+ + S + +LE Q+ + N E K
Sbjct: 2022 DVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKE-KELLVKESESLQARLS 2080
Query: 310 XXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQK 369
S ++++ +++ +L+ +E L + +E + +
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2140
Query: 370 RTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKK 429
+ ++ ER N +K ++E + + ++ + + + E++ + Q + +AR K
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKV 2200
Query: 430 MGDDLHDARA 439
DL R+
Sbjct: 2201 FELDLVTLRS 2210
Score = 43.2 bits (97), Expect = 0.002
Identities = 49/254 (19%), Positives = 105/254 (41%), Gaps = 10/254 (3%)
Query: 40 IRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKL 99
I++ + +++ + EL Q + + ++L L E+L+ E +++ + + ++ +L
Sbjct: 2002 IQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL 2061
Query: 100 RKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
K E + ESE L + + E ++ + ++ K S Q EV++L
Sbjct: 2062 NKEKELLVKESESLQARLSESDYE-KLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRG 2120
Query: 160 VENV-------TKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIEL 212
+E + K+++ I++ + E L K+E L R + ++ Q L + E
Sbjct: 2121 IEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL-QMSEENQELVILDAEN 2179
Query: 213 VK-EVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQ 271
K EV+ LK IE + L +++ L S +
Sbjct: 2180 SKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSL 2239
Query: 272 LEEESEARLDLERQ 285
LEE+ +A + ++ +
Sbjct: 2240 LEEKEQAEIQIKEE 2253
Score = 40.7 bits (91), Expect = 0.012
Identities = 72/415 (17%), Positives = 165/415 (39%), Gaps = 18/415 (4%)
Query: 28 ADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFE 87
A++ + + ++Q+ L+ E + ++ + L +EE S +
Sbjct: 2246 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2305
Query: 88 INRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKS 147
+ + + + K +L+ + ESE A LLK + + + + + +I + + A E E S
Sbjct: 2306 LRARLEADEKKQLCVLQQLK-ESEHHADLLKGRVENL--ERELEIARTNQEHAALEAENS 2362
Query: 148 KFQAEVYELLAQVENVTK-----EKITISKTCERLEITISELHIKIEELNRTIVDITSHK 202
K EV L A++E +T+ E ++ E+ +T +EL + E ++ + +S +
Sbjct: 2363 K--GEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLT-NELQKEQERISELEIINSSFE 2419
Query: 203 QRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVE 262
L ++ E V+ + +E + ++ + + + +E
Sbjct: 2420 NILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLE 2479
Query: 263 IDLESVRVQLEEESEARLDLERQLVKANGEIGHWRSKFXXXXXXXXXXXXXXXXKYSXXX 322
++ + L+E + L+ + E+ + K +
Sbjct: 2480 LEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVS 2539
Query: 323 XXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDLEKAN--GTARELQKRTEQLERVNIE 380
+ K N+E + ++ E ++ ++ + A+ T LQ + LE E
Sbjct: 2540 KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN---E 2596
Query: 381 IKSRLEETVQLYEQTQRDLRNKQTELQRVSHEL-DKTREQKDALARENKKMGDDL 434
++ + + E+ + + K+TELQR HE+ KT E ++ L+ E ++ +L
Sbjct: 2597 LELTKMDKMSFVEKVNK-MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGEL 2650
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/175 (23%), Positives = 84/175 (48%), Gaps = 10/175 (5%)
Query: 2 SAMAKTSKYTYRSSGGGTTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREK 61
S +A+TS+ + + N+ + LSAL E +++L+ D +E+E+ Q +++
Sbjct: 876 SFVAETSQRISKLQEDTSAHQNV-VAETLSALENKEKELQLLNDKVETEQAEIQELKKSN 934
Query: 62 ADL--SVQVIQL-SERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLE-SEETAHLL 117
L S++ +QL SE L + S +N++ EL + L++++ ++E +L+
Sbjct: 935 HLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLI 994
Query: 118 KKKNQ-EIVIDFQEQIDQLTKTKARAEK----EKSKFQAEVYELLAQVENVTKEK 167
+K ID +E+ + + EK ++ + YE L+Q +EK
Sbjct: 995 QKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK 1049
Score = 35.1 bits (77), Expect = 0.59
Identities = 23/91 (25%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 341 KQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLR 400
K + LQ+ V+ L LE +LQK+ E+L ++ EI+ L + Q+++ +
Sbjct: 823 KNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETS 882
Query: 401 NKQTELQR-VSHELDKTREQKDALARENKKM 430
+ ++LQ S + E AL + K++
Sbjct: 883 QRISKLQEDTSAHQNVVAETLSALENKEKEL 913
Score = 35.1 bits (77), Expect = 0.59
Identities = 38/170 (22%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 52 ELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESE 111
E QRI + + D S ++E L E + +N K +TE ++++L + HL +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLED 939
Query: 112 ---------ETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVEN 162
ET L KK+ I+ + +I++LT+ ++ + E L+ + E+
Sbjct: 940 SLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSES 999
Query: 163 ----VTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQE 208
+ + + +IS+ ++ + L + EE D+ S K + +QE
Sbjct: 1000 FANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDL-SQKYKAAQE 1048
Score = 35.1 bits (77), Expect = 0.59
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 335 KINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQ 394
K+ EK+K LQ E++ + DLE +N + Q+ L+ I+ + +
Sbjct: 1223 KLQESEKEKECLQHELQTIRGDLETSNLQDMQSQE-ISGLKDCEIDAEEKYISGPHELST 1281
Query: 395 TQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARA 439
+Q D + Q LQ ++L++ + + L E ++ +L+D+R+
Sbjct: 1282 SQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRS 1326
Score = 34.7 bits (76), Expect = 0.79
Identities = 39/202 (19%), Positives = 94/202 (46%), Gaps = 12/202 (5%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKA----DLSVQVIQLSERLEEAEGGAESQFEINRKR 92
E+++R ++++ E L + +KA L ++ + + L +++ AE N +
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQ 533
Query: 93 DTELLKLRKLL--EDVHLESEE----TAHLLKKKN--QEIVIDFQEQIDQLTKTKARAEK 144
+T L L++ + ++ L E+ A L K+++ Q+++ + I+QL ++ EK
Sbjct: 534 ETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEK 593
Query: 145 EKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQR 204
E + + + E + +EK S E ++++ + E L I + + +
Sbjct: 594 ESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKT 653
Query: 205 LSQENIELVKEVQDLKVNIENV 226
++ E + V+ L+++ EN+
Sbjct: 654 QQIKSHEYNERVRTLEMDRENL 675
Score = 34.3 bits (75), Expect = 1.0
Identities = 41/203 (20%), Positives = 92/203 (45%), Gaps = 11/203 (5%)
Query: 44 QDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT---ELLKLR 100
+D +E E ++R+ I + L + L + E + + R++ T E L +
Sbjct: 2683 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2742
Query: 101 KLLEDVHLESEETAHLLKKKNQEIVIDFQE-QIDQLTKTKARAEKEKSKFQAEVYELLAQ 159
KL D+ S+E + K +I+ + ++ ++D L K + +KE + Q ++ L+
Sbjct: 2743 KLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL-KYVNQLKKENERAQGKMKLLIKS 2801
Query: 160 VENVTKEKITISKTCERLEI------TISELHIKIEELNRTIVDITSHKQRLSQENIELV 213
+ + +EK + K +L+ T + + K++EL I ++ + ++E E +
Sbjct: 2802 CKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYL 2861
Query: 214 KEVQDLKVNIENVVYLKSQIASQ 236
+ L ++ E + K + +Q
Sbjct: 2862 DKYCSLLISHEKLEKAKEMLETQ 2884
Score = 32.3 bits (70), Expect = 4.2
Identities = 22/105 (20%), Positives = 57/105 (54%), Gaps = 7/105 (6%)
Query: 336 INNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQT 395
++ ++ Q L++++ L + L+ G +E++ + + + + ++++ + V+L E+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQ---GHEKEMKGQVNKFQELQLQLE---KAKVELIEK- 332
Query: 396 QRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDLHDARAN 440
++ L + EL R + + D+ + AL ++ KK+ +DL R N
Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQN 377
Score = 31.5 bits (68), Expect = 7.3
Identities = 19/103 (18%), Positives = 50/103 (48%)
Query: 332 LIAKINNVEKQKSRLQSEVEVLIIDLEKANGTARELQKRTEQLERVNIEIKSRLEETVQL 391
L +++ ++K+K + Q +++ L L+K + L+R N + E +
Sbjct: 23 LEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICESLEKT 82
Query: 392 YEQTQRDLRNKQTELQRVSHELDKTREQKDALARENKKMGDDL 434
++ +L+ K++++ +L+ ++Q + L +E K+ +L
Sbjct: 83 KQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSEL 125
>AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 47.6 bits (108), Expect = 1e-04
Identities = 43/205 (20%), Positives = 101/205 (49%), Gaps = 20/205 (9%)
Query: 38 DKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELL 97
+K R ++D + R+ + IER+ +L ++ + E E+ AE Q +I ++ EL
Sbjct: 251 EKSRQLRDAQQDARDKMEDIERQVRELKTKISAMKEEKEQLS--AERQEQIKQRTKLEL- 307
Query: 98 KLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELL 157
K + L +++ SE+ LLK++ Q+++ +E+ +L +T+ + K K + + L
Sbjct: 308 KAKDLQDELAGNSEQRKRLLKER-QKLLEKIEEKQKELAETEPKFNSVKEKEERGIARLA 366
Query: 158 AQVENVT--------------KEKIT--ISKTCERLEITISELHIKIEELNRTIVDITSH 201
+ T KE+ I K + L+ I++ +I +++ + D ++
Sbjct: 367 QATQERTDLYAKQGRGSQFTSKEERDKWIKKELKSLDQAINDKKRQIAAIHKDLEDTEAN 426
Query: 202 KQRLSQENIELVKEVQDLKVNIENV 226
K++ ++ +L +++ ++K +E +
Sbjct: 427 KEKNLEQYNKLDQDLNEVKARVEEL 451
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/194 (21%), Positives = 89/194 (45%), Gaps = 9/194 (4%)
Query: 22 VNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGG 81
++ E + ++LE K + +QD+L E R+R+ +E+ L ++ + + L E E
Sbjct: 291 LSAERQEQIKQRTKLELKAKDLQDELAGNSEQRKRLLKERQKLLEKIEEKQKELAETEPK 350
Query: 82 AESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKAR 141
S E + L + + D++ + + K+ ++ + I + K+ +
Sbjct: 351 FNSVKEKEERGIARLAQATQERTDLYAKQGRGSQFTSKEERD------KWIKKELKSLDQ 404
Query: 142 AEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH 201
A +K + A +++ L E KEK + +L+ ++E+ ++EEL+R ++ +
Sbjct: 405 AINDKKRQIAAIHKDLEDTE-ANKEKNL--EQYNKLDQDLNEVKARVEELDRKYYEVKNK 461
Query: 202 KQRLSQENIELVKE 215
K L E L +E
Sbjct: 462 KDELQSERNYLWRE 475
Score = 36.3 bits (80), Expect = 0.26
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 6/149 (4%)
Query: 93 DTELLKLRKLLEDVHLESEETAHLLKKKNQEI---VIDFQEQIDQLTKTKARAEKEKSKF 149
DT +L +L +DV EE L K N+ + + +IDQL + E ++ KF
Sbjct: 670 DTRKSRL-ELQKDVRKAEEELGELEAKLNENLRRNIERINNEIDQLMNQMQQIETQQRKF 728
Query: 150 QAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSH--KQRLSQ 207
+A +L++++ + +++ KT + ++ L + + T + + LSQ
Sbjct: 729 KASRDSILSEMKMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQ 788
Query: 208 ENIELVKEVQDLKVNIENVVYLKSQIASQ 236
++E K V L I + Q+ ++
Sbjct: 789 LSLEDQKRVDALNDEIRQLQQENRQLLNE 817
>AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1732
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein
kinase alpha (DMPK-like) protein.
Length = 1719
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/180 (20%), Positives = 87/180 (48%), Gaps = 6/180 (3%)
Query: 36 LEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTE 95
L+D R I+ E++++ +++E+ DL+ +++Q SERL+ + + E
Sbjct: 523 LDDAFRQIK---AYEKQIKT-LQQEREDLNKELVQASERLKNQSKELKDAHCQRKLAMQE 578
Query: 96 LLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYE 155
+++ + L ++H + ++ A ++ K +E+ + Q +++ L + R E+ K + +
Sbjct: 579 FMEINERLTELHTQKQKLARHVRDKEEEVDLVMQ-KVESLRQELRRTERAKKELEVHTEA 637
Query: 156 LLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKE 215
L A+ K + ++LE + L K + + I H+Q +++ +L K+
Sbjct: 638 LAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSI-EHQQEITKLKTDLEKK 696
Score = 38.3 bits (85), Expect = 0.064
Identities = 40/202 (19%), Positives = 90/202 (44%), Gaps = 18/202 (8%)
Query: 32 ALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGA---ESQFEI 88
A LE + + +R+LR++ E L ++ L ++ G E Q EI
Sbjct: 627 AKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQQEI 686
Query: 89 NRKRDTELLKLRKLLEDVHLESEETAHLLKKKN----------QEIVIDFQEQI--DQLT 136
+ + T+L K + + + L E H + KN Q++ ++ + I D+L
Sbjct: 687 TKLK-TDLEK-KSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKLE 744
Query: 137 KTKARAEKEKSKFQAEVYELLAQVE-NVTKEKITISKTCERLEITISELHIKIEELNRTI 195
KT+ ++ E+ +F++E + + + +T+E ++ ++L L I ++L +
Sbjct: 745 KTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQQLEEEV 804
Query: 196 VDITSHKQRLSQENIELVKEVQ 217
D+ K+ ++ ++ + +Q
Sbjct: 805 KDLADKKESVAHWEAQITEIIQ 826
>AF161352-1|AAF28912.1| 290|Homo sapiens HSPC089 protein.
Length = 290
Score = 47.6 bits (108), Expect = 1e-04
Identities = 55/253 (21%), Positives = 114/253 (45%), Gaps = 16/253 (6%)
Query: 51 RELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLES 110
+ R +E + A L +L + E+ + + + E +++ L K +L +DV +
Sbjct: 1 KRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK--QLFDDV--QK 56
Query: 111 EETAHLLKKKNQEIVI-DFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKE--K 167
EE +L +K+ E+ D+++QI L + + EK + Q L + E+VT + K
Sbjct: 57 EERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQH-----LVEGEHVTSDGLK 111
Query: 168 ITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVV 227
+++ ++++ TISE +IE L +D+ H Q +E E + E+ + ++
Sbjct: 112 AEVARLSKQVK-TISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIE 170
Query: 228 YLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEESEARLDLERQLV 287
++S+++ + + +E +S + E+E EA L ++V
Sbjct: 171 DVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEA---LNFKVV 227
Query: 288 KANGEIGHWRSKF 300
+ EI H + F
Sbjct: 228 HLSQEINHLQKLF 240
Score = 34.3 bits (75), Expect = 1.0
Identities = 43/214 (20%), Positives = 92/214 (42%), Gaps = 9/214 (4%)
Query: 19 TTDVNIEYSADLSALSRLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEA 78
T D + + + L+D+ +Q +E E ++ E A LS QV +SE +E
Sbjct: 72 TQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEI 131
Query: 79 EGGAESQFEINRKRDTELLKLRKLLEDVH---LES---EETAHLLKKKNQEIVIDFQEQI 132
E + ++ + ++ ++R+ + ++ LES E+ L ++ E + + E
Sbjct: 132 ELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELW 191
Query: 133 DQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELN 192
K +S FQ++ ++E + + + +S+ L+ E + E +
Sbjct: 192 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIR 251
Query: 193 RTIVDITSHKQRL---SQENIELVKEVQDLKVNI 223
+ +TS + Q+ EL K+ QDL++ +
Sbjct: 252 HEVTRLTSENMMIPDFKQQIPELEKQKQDLEIRL 285
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/255 (18%), Positives = 111/255 (43%), Gaps = 28/255 (10%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI------NR 90
E++ +Q ++E+ L++R++ DL + ++ E+ GA S +++ N
Sbjct: 298 EERAESLQQEVEA---LKERVDELTTDLEILKAEIEEK---GSDGAASSYQLKQLEEQNA 351
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ L+++R L E + L++KKNQE+ + Q+ + R ++E S+ +
Sbjct: 352 RLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ--------RERLQEELSQAE 403
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ + EL QV+ + + +R + + E K+ EL T+ D+ + +++ N
Sbjct: 404 STIDELKEQVDAALGAEEMVEMLTDR-NLNLEE---KVRELRETVGDL----EAMNEMND 455
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL + ++ ++ + + + + Q+ L+ V
Sbjct: 456 ELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNR 515
Query: 271 QLEEESEARLDLERQ 285
+L + EA ++ ++Q
Sbjct: 516 ELTNQQEASVERQQQ 530
Score = 45.6 bits (103), Expect = 4e-04
Identities = 77/371 (20%), Positives = 140/371 (37%), Gaps = 39/371 (10%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E+ L QV L E+LE + KR + KL++L + H E K
Sbjct: 198 KEEEGLRAQVRDLEEKLET----------LRLKRAEDKAKLKEL--EKHKIQLEQVQEWK 245
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
K QE D Q ++ + K A + K ++ E+ + +E T +K + E L+
Sbjct: 246 SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQ 305
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXX 238
+ L +++EL D+ K + ++ + LK E LK +
Sbjct: 306 QEVEALKERVDELT---TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 362
Query: 239 XXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-SEARLDLERQLVKANGEIGHWR 297
++E+ + R +L+EE S+A ++ + + +G
Sbjct: 363 LSSSEKQEHVKLQKLMEKKNQELEV-VRQQRERLQEELSQAESTIDELKEQVDAALG--- 418
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
+ + ++N+ E Q++ ++E+E L L
Sbjct: 419 ----AEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMND-ELQENARETELE-LREQL 472
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ A RE QKR E + ETV Y+QT + R LQ V+ EL T
Sbjct: 473 DMAGARVREAQKRVEAAQ-----------ETVADYQQTIKKYRQLTAHLQDVNREL--TN 519
Query: 418 EQKDALARENK 428
+Q+ ++ R+ +
Sbjct: 520 QQEASVERQQQ 530
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ + +LE R+ R+R++ E + + +L E+++ A GAE E+ R+
Sbjct: 373 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL-GAEEMVEMLTDRNL 431
Query: 95 EL-LKLRKLLEDV-HLES-EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
L K+R+L E V LE+ E L++ +E ++ +EQ+D A+K Q
Sbjct: 432 NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQE 491
Query: 152 EV 153
V
Sbjct: 492 TV 493
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/255 (18%), Positives = 111/255 (43%), Gaps = 28/255 (10%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI------NR 90
E++ +Q ++E+ L++R++ DL + ++ E+ GA S +++ N
Sbjct: 181 EERAESLQQEVEA---LKERVDELTTDLEILKAEIEEK---GSDGAASSYQLKQLEEQNA 234
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ L+++R L E + L++KKNQE+ + Q+ + R ++E S+ +
Sbjct: 235 RLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ--------RERLQEELSQAE 286
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ + EL QV+ + + +R + + E K+ EL T+ D+ + +++ N
Sbjct: 287 STIDELKEQVDAALGAEEMVEMLTDR-NLNLEE---KVRELRETVGDL----EAMNEMND 338
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL + ++ ++ + + + + Q+ L+ V
Sbjct: 339 ELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNR 398
Query: 271 QLEEESEARLDLERQ 285
+L + EA ++ ++Q
Sbjct: 399 ELTNQQEASVERQQQ 413
Score = 45.6 bits (103), Expect = 4e-04
Identities = 77/371 (20%), Positives = 140/371 (37%), Gaps = 39/371 (10%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E+ L QV L E+LE + KR + KL++L + H E K
Sbjct: 81 KEEEGLRAQVRDLEEKLET----------LRLKRAEDKAKLKEL--EKHKIQLEQVQEWK 128
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
K QE D Q ++ + K A + K ++ E+ + +E T +K + E L+
Sbjct: 129 SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQ 188
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXX 238
+ L +++EL D+ K + ++ + LK E LK +
Sbjct: 189 QEVEALKERVDELT---TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 245
Query: 239 XXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-SEARLDLERQLVKANGEIGHWR 297
++E+ + R +L+EE S+A ++ + + +G
Sbjct: 246 LSSSEKQEHVKLQKLMEKKNQELEV-VRQQRERLQEELSQAESTIDELKEQVDAALG--- 301
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
+ + ++N+ E Q++ ++E+E L L
Sbjct: 302 ----AEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMND-ELQENARETELE-LREQL 355
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ A RE QKR E + ETV Y+QT + R LQ V+ EL T
Sbjct: 356 DMAGARVREAQKRVEAAQ-----------ETVADYQQTIKKYRQLTAHLQDVNREL--TN 402
Query: 418 EQKDALARENK 428
+Q+ ++ R+ +
Sbjct: 403 QQEASVERQQQ 413
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ + +LE R+ R+R++ E + + +L E+++ A GAE E+ R+
Sbjct: 256 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL-GAEEMVEMLTDRNL 314
Query: 95 EL-LKLRKLLEDV-HLES-EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
L K+R+L E V LE+ E L++ +E ++ +EQ+D A+K Q
Sbjct: 315 NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQE 374
Query: 152 EV 153
V
Sbjct: 375 TV 376
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/255 (18%), Positives = 111/255 (43%), Gaps = 28/255 (10%)
Query: 37 EDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEI------NR 90
E++ +Q ++E+ L++R++ DL + ++ E+ GA S +++ N
Sbjct: 315 EERAESLQQEVEA---LKERVDELTTDLEILKAEIEEK---GSDGAASSYQLKQLEEQNA 368
Query: 91 KRDTELLKLRKLLEDVHLESEETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQ 150
+ L+++R L E + L++KKNQE+ + Q+ + R ++E S+ +
Sbjct: 369 RLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQ--------RERLQEELSQAE 420
Query: 151 AEVYELLAQVENVTKEKITISKTCERLEITISELHIKIEELNRTIVDITSHKQRLSQENI 210
+ + EL QV+ + + +R + + E K+ EL T+ D+ + +++ N
Sbjct: 421 STIDELKEQVDAALGAEEMVEMLTDR-NLNLEE---KVRELRETVGDL----EAMNEMND 472
Query: 211 ELVKEVQDLKVNIENVVYLKSQIASQXXXXXXXXXXXXXXXXXXXASLHQVEIDLESVRV 270
EL + ++ ++ + + + + Q+ L+ V
Sbjct: 473 ELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNR 532
Query: 271 QLEEESEARLDLERQ 285
+L + EA ++ ++Q
Sbjct: 533 ELTNQQEASVERQQQ 547
Score = 45.6 bits (103), Expect = 4e-04
Identities = 77/371 (20%), Positives = 140/371 (37%), Gaps = 39/371 (10%)
Query: 59 REKADLSVQVIQLSERLEEAEGGAESQFEINRKRDTELLKLRKLLEDVHLESEETAHLLK 118
+E+ L QV L E+LE + KR + KL++L + H E K
Sbjct: 215 KEEEGLRAQVRDLEEKLET----------LRLKRAEDKAKLKEL--EKHKIQLEQVQEWK 262
Query: 119 KKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQAEVYELLAQVENVTKEKITISKTCERLE 178
K QE D Q ++ + K A + K ++ E+ + +E T +K + E L+
Sbjct: 263 SKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQ 322
Query: 179 ITISELHIKIEELNRTIVDITSHKQRLSQENIELVKEVQDLKVNIENVVYLKSQIASQXX 238
+ L +++EL D+ K + ++ + LK E LK +
Sbjct: 323 QEVEALKERVDELT---TDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 379
Query: 239 XXXXXXXXXXXXXXXXXASLHQVEIDLESVRVQLEEE-SEARLDLERQLVKANGEIGHWR 297
++E+ + R +L+EE S+A ++ + + +G
Sbjct: 380 LSSSEKQEHVKLQKLMEKKNQELEV-VRQQRERLQEELSQAESTIDELKEQVDAALG--- 435
Query: 298 SKFXXXXXXXXXXXXXXXXKYSXXXXXXXXXXXTLIAKINNVEKQKSRLQSEVEVLIIDL 357
+ + ++N+ E Q++ ++E+E L L
Sbjct: 436 ----AEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMND-ELQENARETELE-LREQL 489
Query: 358 EKANGTARELQKRTEQLERVNIEIKSRLEETVQLYEQTQRDLRNKQTELQRVSHELDKTR 417
+ A RE QKR E + ETV Y+QT + R LQ V+ EL T
Sbjct: 490 DMAGARVREAQKRVEAAQ-----------ETVADYQQTIKKYRQLTAHLQDVNREL--TN 536
Query: 418 EQKDALARENK 428
+Q+ ++ R+ +
Sbjct: 537 QQEASVERQQQ 547
Score = 38.3 bits (85), Expect = 0.064
Identities = 33/122 (27%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 35 RLEDKIRLIQDDLESERELRQRIEREKADLSVQVIQLSERLEEAEGGAESQFEINRKRDT 94
+L+ + +LE R+ R+R++ E + + +L E+++ A GAE E+ R+
Sbjct: 390 KLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAAL-GAEEMVEMLTDRNL 448
Query: 95 EL-LKLRKLLEDV-HLES-EETAHLLKKKNQEIVIDFQEQIDQLTKTKARAEKEKSKFQA 151
L K+R+L E V LE+ E L++ +E ++ +EQ+D A+K Q
Sbjct: 449 NLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQE 508
Query: 152 EV 153
V
Sbjct: 509 TV 510
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.309 0.126 0.318
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 45,413,074
Number of Sequences: 224733
Number of extensions: 1543719
Number of successful extensions: 27821
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 550
Number of HSP's successfully gapped in prelim test: 1466
Number of HSP's that attempted gapping in prelim test: 13697
Number of HSP's gapped (non-prelim): 11968
length of query: 512
length of database: 73,234,838
effective HSP length: 93
effective length of query: 419
effective length of database: 52,334,669
effective search space: 21928226311
effective search space used: 21928226311
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.7 bits)
S2: 67 (31.1 bits)
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