Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000602-TA|BGIBMGA000602-PA|IPR000494|EGF receptor, L
domain, IPR006211|Furin-like cysteine rich region, IPR001245|Tyrosine
protein kinase, IPR011009|Protein kinase-like, IPR009030|Growth
factor, receptor, IPR000719|Protein kinase, IPR008266|Tyrosine protein
kinase, active site, IPR006212|Furin-like repeat
(1397 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 497 e-140
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 497 e-140
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 497 e-140
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 472 e-132
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 472 e-132
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 472 e-132
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 472 e-132
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 472 e-132
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 472 e-132
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 458 e-128
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 458 e-128
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 458 e-128
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 423 e-117
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 423 e-117
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 422 e-117
AY698023-1|AAT97978.1| 645|Homo sapiens epidermal growth factor... 398 e-110
K03193-1|AAA52371.1| 657|Homo sapiens EGFR protein. 397 e-109
AF288738-4|AAG35790.1| 628|Homo sapiens truncated epidermal gro... 397 e-109
AF288738-3|AAG35786.1| 705|Homo sapiens p110 epidermal growth f... 397 e-109
AF288738-2|AAG35788.1| 657|Homo sapiens A431-specific p115 epid... 397 e-109
AF125253-1|AAG43240.1| 705|Homo sapiens truncated epidermal gro... 397 e-109
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 390 e-107
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 371 e-102
AC105921-1|AAY24303.1| 552|Homo sapiens unknown protein. 352 4e-96
BC118665-1|AAI18666.1| 464|Homo sapiens EGFR protein protein. 313 3e-84
AK131568-1|BAD18701.1| 435|Homo sapiens protein ( Homo sapiens ... 281 1e-74
AC012069-1|AAY15092.1| 479|Homo sapiens unknown protein. 277 2e-73
AC073324-1|AAS07524.1| 387|Homo sapiens unknown protein. 264 2e-69
U95089-1|AAB53063.1| 405|Homo sapiens truncated epidermal growt... 256 4e-67
U48722-1|AAC50802.1| 405|Homo sapiens epidermal growth factor r... 256 4e-67
AY698024-1|AAT97979.1| 405|Homo sapiens epidermal growth factor... 256 4e-67
AF288738-5|AAG35787.1| 405|Homo sapiens p60 epidermal growth fa... 256 4e-67
M12036-1|AAA35978.1| 171|Homo sapiens protein ( Human tyrosine ... 246 3e-64
BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic... 237 3e-61
BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein. 237 3e-61
BC128419-1|AAI28420.1| 388|Homo sapiens OSGIN2 protein protein. 221 1e-56
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 216 5e-55
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 216 5e-55
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 216 5e-55
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 216 5e-55
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 216 5e-55
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 216 5e-55
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 216 5e-55
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 216 5e-55
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 216 5e-55
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 216 5e-55
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 214 2e-54
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 214 2e-54
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 214 2e-54
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 214 2e-54
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 214 2e-54
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 214 2e-54
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 214 2e-54
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 214 2e-54
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 214 2e-54
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 214 2e-54
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 213 4e-54
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 213 4e-54
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 213 4e-54
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 213 5e-54
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 213 5e-54
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 213 5e-54
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 210 4e-53
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 210 4e-53
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 209 6e-53
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 209 6e-53
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 209 6e-53
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 208 1e-52
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 208 1e-52
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 208 1e-52
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 206 6e-52
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 206 6e-52
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 206 6e-52
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 205 8e-52
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 205 1e-51
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 205 1e-51
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 205 1e-51
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 205 1e-51
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 205 1e-51
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 204 2e-51
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 204 2e-51
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 204 2e-51
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 203 4e-51
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 202 5e-51
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 201 1e-50
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 201 1e-50
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 201 2e-50
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 201 2e-50
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 201 2e-50
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 201 2e-50
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 201 2e-50
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 201 2e-50
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 201 2e-50
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 200 3e-50
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 200 3e-50
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 200 3e-50
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 200 3e-50
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 200 3e-50
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 200 3e-50
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 200 3e-50
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 200 3e-50
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 200 3e-50
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 200 3e-50
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 200 3e-50
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 200 3e-50
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 200 3e-50
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 200 3e-50
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 200 4e-50
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 200 4e-50
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 200 4e-50
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 200 4e-50
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 200 4e-50
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 198 9e-50
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 198 9e-50
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 198 9e-50
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 198 9e-50
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 198 9e-50
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 198 9e-50
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 198 9e-50
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 198 1e-49
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 198 1e-49
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 198 1e-49
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 198 1e-49
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 197 2e-49
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 197 2e-49
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 197 2e-49
AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein. 197 2e-49
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 197 2e-49
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 197 3e-49
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 197 3e-49
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 197 3e-49
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 197 3e-49
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 197 3e-49
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 197 3e-49
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 196 4e-49
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 196 4e-49
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 196 6e-49
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 195 1e-48
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 195 1e-48
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 195 1e-48
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 195 1e-48
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 195 1e-48
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 195 1e-48
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 195 1e-48
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 195 1e-48
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 195 1e-48
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 195 1e-48
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 195 1e-48
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 195 1e-48
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 195 1e-48
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 195 1e-48
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 194 1e-48
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 194 1e-48
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 194 1e-48
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 191 1e-47
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 191 2e-47
AB209338-1|BAD92575.1| 400|Homo sapiens Hypothetical protein FL... 190 2e-47
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 190 3e-47
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 190 3e-47
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 190 4e-47
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 190 4e-47
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 189 5e-47
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 189 5e-47
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 189 5e-47
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 189 5e-47
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 189 5e-47
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 189 5e-47
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 188 1e-46
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 187 2e-46
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 187 3e-46
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 187 3e-46
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 187 3e-46
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 187 3e-46
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 187 3e-46
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 187 3e-46
AC068970-1|AAX88856.1| 136|Homo sapiens unknown protein. 186 7e-46
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 185 1e-45
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 185 1e-45
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 184 2e-45
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 184 2e-45
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 184 2e-45
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 184 2e-45
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 184 2e-45
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 184 2e-45
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 184 2e-45
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 184 2e-45
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 183 3e-45
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 183 3e-45
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 183 3e-45
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 183 3e-45
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 183 3e-45
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 183 3e-45
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 183 3e-45
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 183 3e-45
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 183 5e-45
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 182 6e-45
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 182 8e-45
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 182 8e-45
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 182 1e-44
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 182 1e-44
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 182 1e-44
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 181 2e-44
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 181 2e-44
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 181 2e-44
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 181 2e-44
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 181 2e-44
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 181 2e-44
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 181 2e-44
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 180 2e-44
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 180 3e-44
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 180 3e-44
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 180 3e-44
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 180 4e-44
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 180 4e-44
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 180 4e-44
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 180 4e-44
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 179 6e-44
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 179 6e-44
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 179 6e-44
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 179 6e-44
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 179 6e-44
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 179 8e-44
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 178 1e-43
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 177 2e-43
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 177 2e-43
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 177 2e-43
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 177 2e-43
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 177 2e-43
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 177 2e-43
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 177 2e-43
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 177 2e-43
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 177 2e-43
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 177 2e-43
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 177 2e-43
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 177 2e-43
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 177 2e-43
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 177 2e-43
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 177 2e-43
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 177 2e-43
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 177 2e-43
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 177 2e-43
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 177 2e-43
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 177 2e-43
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 177 2e-43
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 177 3e-43
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 176 4e-43
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 176 4e-43
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 176 4e-43
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 176 4e-43
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 176 4e-43
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 176 4e-43
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 176 4e-43
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 176 4e-43
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 176 4e-43
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 176 5e-43
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 176 5e-43
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 176 5e-43
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 176 5e-43
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 176 5e-43
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 176 5e-43
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 176 5e-43
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 176 5e-43
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 176 5e-43
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 176 5e-43
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 176 5e-43
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 176 5e-43
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 176 5e-43
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 176 5e-43
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 176 5e-43
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 176 5e-43
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 176 5e-43
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 176 5e-43
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 176 5e-43
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 176 5e-43
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 176 5e-43
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 176 5e-43
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 176 5e-43
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 175 7e-43
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 175 9e-43
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 175 9e-43
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 175 9e-43
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 175 9e-43
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 175 9e-43
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 175 9e-43
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 175 9e-43
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 175 9e-43
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 175 9e-43
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 175 9e-43
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 175 9e-43
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 175 9e-43
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 175 9e-43
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 174 2e-42
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 174 2e-42
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 174 2e-42
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 174 2e-42
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 174 2e-42
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 174 2e-42
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 174 2e-42
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 174 2e-42
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 174 2e-42
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 174 2e-42
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 174 2e-42
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 174 2e-42
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 173 3e-42
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 173 5e-42
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 172 7e-42
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 172 7e-42
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 172 7e-42
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 172 9e-42
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 172 9e-42
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 171 1e-41
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 171 2e-41
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 171 2e-41
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 171 2e-41
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 171 2e-41
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 171 2e-41
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 171 2e-41
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 171 2e-41
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 171 2e-41
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 171 2e-41
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 171 2e-41
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 171 2e-41
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 170 3e-41
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 169 5e-41
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 169 5e-41
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 169 5e-41
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 169 5e-41
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 169 5e-41
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 169 6e-41
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 169 8e-41
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 168 1e-40
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 167 2e-40
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 167 2e-40
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 167 2e-40
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 167 2e-40
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 167 2e-40
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 167 2e-40
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 167 2e-40
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 167 2e-40
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 167 2e-40
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 167 2e-40
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 167 3e-40
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 167 3e-40
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 165 1e-39
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 165 1e-39
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 165 1e-39
L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein. 165 1e-39
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 165 1e-39
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 165 1e-39
BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a prote... 165 1e-39
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 165 1e-39
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 165 1e-39
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 165 1e-39
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 165 1e-39
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 165 1e-39
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 165 1e-39
AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant ... 165 1e-39
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 165 1e-39
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 165 1e-39
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 165 1e-39
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 165 1e-39
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 165 1e-39
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 165 1e-39
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 164 2e-39
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 164 2e-39
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 163 4e-39
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 162 7e-39
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 162 7e-39
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 161 1e-38
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 161 2e-38
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 161 2e-38
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 161 2e-38
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 161 2e-38
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 161 2e-38
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 160 4e-38
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 160 4e-38
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 160 4e-38
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 160 4e-38
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 159 5e-38
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 159 5e-38
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 159 5e-38
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 159 5e-38
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 159 5e-38
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 159 5e-38
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 159 5e-38
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 159 5e-38
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 159 7e-38
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 159 7e-38
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 159 7e-38
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 159 7e-38
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 159 7e-38
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 159 9e-38
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 159 9e-38
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 158 2e-37
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 158 2e-37
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 158 2e-37
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 158 2e-37
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 157 2e-37
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 157 2e-37
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 157 2e-37
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 157 2e-37
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 157 2e-37
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 157 2e-37
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 157 2e-37
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 157 2e-37
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 157 2e-37
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 157 2e-37
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 157 2e-37
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 157 2e-37
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 157 3e-37
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 157 3e-37
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 157 3e-37
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 157 3e-37
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 157 3e-37
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 157 3e-37
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 157 3e-37
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 156 5e-37
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 156 5e-37
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 156 5e-37
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 156 5e-37
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 156 5e-37
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 156 5e-37
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 156 5e-37
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 156 5e-37
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 156 6e-37
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 156 6e-37
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 156 6e-37
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 156 6e-37
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 156 6e-37
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 156 6e-37
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 156 6e-37
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 156 6e-37
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 155 1e-36
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 155 1e-36
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 155 1e-36
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 155 1e-36
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 155 1e-36
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 155 1e-36
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 155 1e-36
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 153 6e-36
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 151 1e-35
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 151 2e-35
U31601-1|AAC50226.1| 1094|Homo sapiens JAK3B protein. 150 4e-35
BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein. 148 1e-34
AB219242-1|BAE02826.1| 1141|Homo sapiens janus kinase 1 protein. 148 2e-34
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 145 9e-34
D83492-1|BAA21560.1| 1006|Homo sapiens Eph-family protein protein. 145 9e-34
BC110607-1|AAI10608.2| 1006|Homo sapiens EPH receptor B6 protein. 145 9e-34
BC110606-1|AAI10607.1| 729|Homo sapiens EPHB6 protein protein. 145 9e-34
AY280502-1|AAP20939.1| 1006|Homo sapiens EPHB6 protein. 145 9e-34
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 145 1e-33
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 145 1e-33
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 145 1e-33
BC112933-1|AAI12934.1| 387|Homo sapiens Unknown (protein for MG... 145 1e-33
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 144 2e-33
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 144 2e-33
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 144 2e-33
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 144 3e-33
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 143 3e-33
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 143 3e-33
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 143 3e-33
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 143 3e-33
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 143 5e-33
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 143 5e-33
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 142 6e-33
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 142 6e-33
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 142 6e-33
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 141 1e-32
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 141 1e-32
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 141 1e-32
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 141 1e-32
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 141 1e-32
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 141 1e-32
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 140 2e-32
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 140 2e-32
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 140 2e-32
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 140 3e-32
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 140 3e-32
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 140 3e-32
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 140 3e-32
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 497 bits (1227), Expect = e-140
Identities = 267/559 (47%), Positives = 355/559 (63%), Gaps = 55/559 (9%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP--SDHFTD-EIGRNCTPCHSECKG- 687
C+ LC +G C C F RG C + C F + E G C C +C+
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 562
Query: 688 ------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQDP 741
C GPGP +C KC + K + P NC + CPD + F + DP
Sbjct: 563 EDGLLTCHGPGPDNCTKCSHFK-----------DGP-NCVEKCPDGLQGANSFIFKYADP 610
Query: 742 IEE-----PYCSEHANDIPTA--------TARTS------TVLVIILVIASLFLAVLAII 782
E P C++ N PT+ T ++ T L+ VI LF +L I+
Sbjct: 611 DRECHPCHPNCTQGCNG-PTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLF--ILVIV 667
Query: 783 GYNF----RQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGML 838
G F R+K+ KK A++ + E EPL P+ PN A+LRI+KE EL+R +L
Sbjct: 668 GLTFAVYVRRKSIKKKRALRRFLET---ELVEPLTPSGTAPNQAQLRILKETELKRVKVL 724
Query: 839 GFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLL 898
G GAFG VYKG+WVPEGE VKIPVAIK+L ETTG + EF++EA IMAS++HP+L++LL
Sbjct: 725 GSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLL 784
Query: 899 AVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDL 958
VC++ + L+TQLMP GCL++YV HK+ IGS+ LNWC QIA+GM YLEE+RLVHRDL
Sbjct: 785 GVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDL 844
Query: 959 AARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVW 1018
AARNVLV++PN VKITDFGLA+LL+ +E EY A GGKMPIKW+ALECI +R FTH+SDVW
Sbjct: 845 AARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVW 904
Query: 1019 AFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSR 1078
++GVTIWE++++G +PY+ I R +P+L+E G +LPQP ICT+D+Y VMV CWM+DADSR
Sbjct: 905 SYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSR 964
Query: 1079 PTFKQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDAD 1138
P FK+LA F+ MARDP RYLVI GD M+LPS ++ + +NL E E ++DA+
Sbjct: 965 PKFKELAAEFSRMARDPQRYLVIQGDDRMKLPS---PNDSKFFQNLLDE-EDLEDMMDAE 1020
Query: 1139 EYLQPKFKSMTGTVTTNSA 1157
EYL P+ ++ + T+ A
Sbjct: 1021 EYLVPQAFNIPPPIYTSRA 1039
Score = 407 bits (1003), Expect = e-112
Identities = 222/577 (38%), Positives = 317/577 (54%), Gaps = 45/577 (7%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+S S+ + YR LR + NC V GNLE+T +E+ + DLSFL+ +REVTGYVL++ +
Sbjct: 36 LSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMSTA----FTLE---LPALRDVLQGSVGI 113
+ L L+IIRG L+ E+ +AL + ++ F L+ L L ++L G V +
Sbjct: 95 RYLPLENLRIIRGTKLY-----EDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYV 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFS 173
N LC+ TI+W +I ++ T + G R G + +CQ +
Sbjct: 150 DQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLT 209
Query: 174 KTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIY 233
+T+C+ QC GRC+GP DCC+ CAGGC+GP T C AC NF D G C +CP +Y
Sbjct: 210 RTVCAEQC-DGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVY 268
Query: 234 NPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPCVG 289
NPTT+ E N N KY YGA CV+ CP + + D+ +CVR+CP +K V NG C PC
Sbjct: 269 NPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTD 328
Query: 290 TCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGER 341
CPK C + + + S NID F +CT I+G++ L TG Y+ E
Sbjct: 329 ICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFL---VTGIH--GDPYNAIE- 382
Query: 342 YPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVK 401
++P+ L VF TVRE+TG+LN+Q+ PN T S F NL IGGR + L SL I+K
Sbjct: 383 --AIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGL--SLLILK 438
Query: 402 -TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEK 460
+++G I I +N NLCY I W L + + + +I+ N C
Sbjct: 439 QQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTA 498
Query: 461 NNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSE 518
+VC+ CS+DGCWGPGPDQCLSC+ ++ G ICI++C+++ G ++ + C +C +
Sbjct: 499 EGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQ 558
Query: 519 C---LDG---CTGASRANCTSCKHVRDGPYCVAQCPE 549
C DG C G NCT C H +DGP CV +CP+
Sbjct: 559 CEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPD 595
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/209 (28%), Positives = 94/209 (44%), Gaps = 25/209 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFA-SLYIVKTXXXXXX 408
L +VREVTGY+ V + + L NL +I G ++ E+ +A ++++
Sbjct: 74 LSFLRSVREVTGYVLVALNQFRYLPLE---NLRIIRGTKLYEDRYALAIFLNYRKDGNFG 130
Query: 409 XXXXXXVN-----SGAIAIMENRNLCYADKIAWNKLVKSK--DHKQIIQKNGDPRQCEKN 461
N +G + + +N+ LCYAD I W +V++ + ++ NG C +
Sbjct: 131 LQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSG-CGR- 188
Query: 462 NLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLD 521
C C+ CWGP + C + E C C G Y +D C CH EC
Sbjct: 189 ---CHKSCTGR-CWGPTENHCQTLTRTVCAEQCDGRCY---GPYVSD---C--CHRECAG 236
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCPES 550
GC+G +C +C + D CV QCP++
Sbjct: 237 GCSGPKDTDCFACMNFNDSGACVTQCPQT 265
Score = 71.7 bits (168), Expect = 2e-11
Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 56/304 (18%)
Query: 16 DRFTNCTYVDGNLE--LTWLEN------ESMD---LSFLKYIREVTGYVLISHVKVHKI- 63
D+F NCT ++GNL +T + E++D L+ + +RE+TG++ I +
Sbjct: 354 DKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTD 413
Query: 64 --VLPQLQIIRGRTLFKLNVREEEFALLVTMSTAFT-LELPALRDVLQGSVGIYSNFNLC 120
V L I GR L+ +LL+ T L+ +L+++ G++ I N NLC
Sbjct: 414 FSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLC 467
Query: 121 HVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQ 180
+ TINW + F+ I N R+V + R A ENC +C+
Sbjct: 468 YYHTINWTTL--------FSTI-------NQRIVIRDNRKA-----ENCTA-EGMVCNHL 506
Query: 181 CAQGRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQ---ECPSMQIYN 234
C+ C+GP P C C F G C R F + C + +C M+
Sbjct: 507 CSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGL 566
Query: 235 PTTYSWEPNPNGKYAY---GATCVRNCPEHLLKDNGACVRSCPPNKTAVNGECIPCVGTC 291
T + P+ K ++ G CV CP+ L N + P++ EC PC C
Sbjct: 567 LTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDR-----ECHPCHPNC 621
Query: 292 PKTC 295
+ C
Sbjct: 622 TQGC 625
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 14/94 (14%)
Query: 452 NGDPRQCEKNNLV--CDPQCSA--DG---CWGPGPDQCLSCQNYNFGEICIDNC-----S 499
+G+ R+ E ++ CDPQC DG C GPGPD C C ++ G C++ C
Sbjct: 540 DGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQG 599
Query: 500 VHPGLYK-AD-HKSCKQCHSECLDGCTGASRANC 531
+ ++K AD + C CH C GC G + +C
Sbjct: 600 ANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 52.8 bits (121), Expect = 8e-06
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 612 NEWVGNVKPLEGKVKIACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHF 670
N W N+ + C +CH C +C +G E CQ +QC+ C +
Sbjct: 169 NPWPSNLTLVSTNGSSGCGRCHKSCTGRC--WGPTENHCQTLTRTVCAEQCDGRCYGPYV 226
Query: 671 TDEIGRNCTPCHSECKG-CTGPGPTDCIKCKN 701
+D C CH EC G C+GP TDC C N
Sbjct: 227 SD-----C--CHRECAGGCSGPKDTDCFACMN 251
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 629 CRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-----SDHFTDEIG---RNCTP 680
C K + C G G C C+ FK G C ++CP ++ F + R C P
Sbjct: 559 CEKMEDGLLTCHGPGPDN--CTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHP 616
Query: 681 CHSEC-KGCTGPGPTDCI 697
CH C +GC GP DCI
Sbjct: 617 CHPNCTQGCNGPTSHDCI 634
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 497 bits (1227), Expect = e-140
Identities = 267/559 (47%), Positives = 355/559 (63%), Gaps = 55/559 (9%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP--SDHFTD-EIGRNCTPCHSECKG- 687
C+ LC +G C C F RG C + C F + E G C C +C+
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 562
Query: 688 ------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQDP 741
C GPGP +C KC + K + P NC + CPD + F + DP
Sbjct: 563 EDGLLTCHGPGPDNCTKCSHFK-----------DGP-NCVEKCPDGLQGANSFIFKYADP 610
Query: 742 IEE-----PYCSEHANDIPTA--------TARTS------TVLVIILVIASLFLAVLAII 782
E P C++ N PT+ T ++ T L+ VI LF +L I+
Sbjct: 611 DRECHPCHPNCTQGCNG-PTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLF--ILVIV 667
Query: 783 GYNF----RQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGML 838
G F R+K+ KK A++ + E EPL P+ PN A+LRI+KE EL+R +L
Sbjct: 668 GLTFAVYVRRKSIKKKRALRRFLET---ELVEPLTPSGTAPNQAQLRILKETELKRVKVL 724
Query: 839 GFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLL 898
G GAFG VYKG+WVPEGE VKIPVAIK+L ETTG + EF++EA IMAS++HP+L++LL
Sbjct: 725 GSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLL 784
Query: 899 AVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDL 958
VC++ + L+TQLMP GCL++YV HK+ IGS+ LNWC QIA+GM YLEE+RLVHRDL
Sbjct: 785 GVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDL 844
Query: 959 AARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVW 1018
AARNVLV++PN VKITDFGLA+LL+ +E EY A GGKMPIKW+ALECI +R FTH+SDVW
Sbjct: 845 AARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVW 904
Query: 1019 AFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSR 1078
++GVTIWE++++G +PY+ I R +P+L+E G +LPQP ICT+D+Y VMV CWM+DADSR
Sbjct: 905 SYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSR 964
Query: 1079 PTFKQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDAD 1138
P FK+LA F+ MARDP RYLVI GD M+LPS ++ + +NL E E ++DA+
Sbjct: 965 PKFKELAAEFSRMARDPQRYLVIQGDDRMKLPS---PNDSKFFQNLLDE-EDLEDMMDAE 1020
Query: 1139 EYLQPKFKSMTGTVTTNSA 1157
EYL P+ ++ + T+ A
Sbjct: 1021 EYLVPQAFNIPPPIYTSRA 1039
Score = 407 bits (1003), Expect = e-112
Identities = 222/577 (38%), Positives = 317/577 (54%), Gaps = 45/577 (7%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+S S+ + YR LR + NC V GNLE+T +E+ + DLSFL+ +REVTGYVL++ +
Sbjct: 36 LSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMSTA----FTLE---LPALRDVLQGSVGI 113
+ L L+IIRG L+ E+ +AL + ++ F L+ L L ++L G V +
Sbjct: 95 RYLPLENLRIIRGTKLY-----EDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYV 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFS 173
N LC+ TI+W +I ++ T + G R G + +CQ +
Sbjct: 150 DQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLT 209
Query: 174 KTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIY 233
+T+C+ QC GRC+GP DCC+ CAGGC+GP T C AC NF D G C +CP +Y
Sbjct: 210 RTVCAEQC-DGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVY 268
Query: 234 NPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPCVG 289
NPTT+ E N N KY YGA CV+ CP + + D+ +CVR+CP +K V NG C PC
Sbjct: 269 NPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTD 328
Query: 290 TCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGER 341
CPK C + + + S NID F +CT I+G++ L TG Y+ E
Sbjct: 329 ICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFL---VTGIH--GDPYNAIE- 382
Query: 342 YPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVK 401
++P+ L VF TVRE+TG+LN+Q+ PN T S F NL IGGR + L SL I+K
Sbjct: 383 --AIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGL--SLLILK 438
Query: 402 -TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEK 460
+++G I I +N NLCY I W L + + + +I+ N C
Sbjct: 439 QQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTA 498
Query: 461 NNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSE 518
+VC+ CS+DGCWGPGPDQCLSC+ ++ G ICI++C+++ G ++ + C +C +
Sbjct: 499 EGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQ 558
Query: 519 C---LDG---CTGASRANCTSCKHVRDGPYCVAQCPE 549
C DG C G NCT C H +DGP CV +CP+
Sbjct: 559 CEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPD 595
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/209 (28%), Positives = 94/209 (44%), Gaps = 25/209 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFA-SLYIVKTXXXXXX 408
L +VREVTGY+ V + + L NL +I G ++ E+ +A ++++
Sbjct: 74 LSFLRSVREVTGYVLVALNQFRYLPLE---NLRIIRGTKLYEDRYALAIFLNYRKDGNFG 130
Query: 409 XXXXXXVN-----SGAIAIMENRNLCYADKIAWNKLVKSK--DHKQIIQKNGDPRQCEKN 461
N +G + + +N+ LCYAD I W +V++ + ++ NG C +
Sbjct: 131 LQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSG-CGR- 188
Query: 462 NLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLD 521
C C+ CWGP + C + E C C G Y +D C CH EC
Sbjct: 189 ---CHKSCTGR-CWGPTENHCQTLTRTVCAEQCDGRCY---GPYVSD---C--CHRECAG 236
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCPES 550
GC+G +C +C + D CV QCP++
Sbjct: 237 GCSGPKDTDCFACMNFNDSGACVTQCPQT 265
Score = 71.7 bits (168), Expect = 2e-11
Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 56/304 (18%)
Query: 16 DRFTNCTYVDGNLE--LTWLEN------ESMD---LSFLKYIREVTGYVLISHVKVHKI- 63
D+F NCT ++GNL +T + E++D L+ + +RE+TG++ I +
Sbjct: 354 DKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTD 413
Query: 64 --VLPQLQIIRGRTLFKLNVREEEFALLVTMSTAFT-LELPALRDVLQGSVGIYSNFNLC 120
V L I GR L+ +LL+ T L+ +L+++ G++ I N NLC
Sbjct: 414 FSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLC 467
Query: 121 HVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQ 180
+ TINW + F+ I N R+V + R A ENC +C+
Sbjct: 468 YYHTINWTTL--------FSTI-------NQRIVIRDNRKA-----ENCTA-EGMVCNHL 506
Query: 181 CAQGRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQ---ECPSMQIYN 234
C+ C+GP P C C F G C R F + C + +C M+
Sbjct: 507 CSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGL 566
Query: 235 PTTYSWEPNPNGKYAY---GATCVRNCPEHLLKDNGACVRSCPPNKTAVNGECIPCVGTC 291
T + P+ K ++ G CV CP+ L N + P++ EC PC C
Sbjct: 567 LTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDR-----ECHPCHPNC 621
Query: 292 PKTC 295
+ C
Sbjct: 622 TQGC 625
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 14/94 (14%)
Query: 452 NGDPRQCEKNNLV--CDPQCSA--DG---CWGPGPDQCLSCQNYNFGEICIDNC-----S 499
+G+ R+ E ++ CDPQC DG C GPGPD C C ++ G C++ C
Sbjct: 540 DGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQG 599
Query: 500 VHPGLYK-AD-HKSCKQCHSECLDGCTGASRANC 531
+ ++K AD + C CH C GC G + +C
Sbjct: 600 ANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 52.8 bits (121), Expect = 8e-06
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 612 NEWVGNVKPLEGKVKIACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHF 670
N W N+ + C +CH C +C +G E CQ +QC+ C +
Sbjct: 169 NPWPSNLTLVSTNGSSGCGRCHKSCTGRC--WGPTENHCQTLTRTVCAEQCDGRCYGPYV 226
Query: 671 TDEIGRNCTPCHSECKG-CTGPGPTDCIKCKN 701
+D C CH EC G C+GP TDC C N
Sbjct: 227 SD-----C--CHRECAGGCSGPKDTDCFACMN 251
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 629 CRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-----SDHFTDEIG---RNCTP 680
C K + C G G C C+ FK G C ++CP ++ F + R C P
Sbjct: 559 CEKMEDGLLTCHGPGPDN--CTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHP 616
Query: 681 CHSEC-KGCTGPGPTDCI 697
CH C +GC GP DCI
Sbjct: 617 CHPNCTQGCNGPTSHDCI 634
>AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 variant protein.
Length = 892
Score = 497 bits (1227), Expect = e-140
Identities = 267/559 (47%), Positives = 355/559 (63%), Gaps = 55/559 (9%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP--SDHFTD-EIGRNCTPCHSECKG- 687
C+ LC +G C C F RG C + C F + E G C C +C+
Sbjct: 103 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 162
Query: 688 ------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQDP 741
C GPGP +C KC + K + P NC + CPD + F + DP
Sbjct: 163 EDGLLTCHGPGPDNCTKCSHFK-----------DGP-NCVEKCPDGLQGANSFIFKYADP 210
Query: 742 IEE-----PYCSEHANDIPTA--------TARTS------TVLVIILVIASLFLAVLAII 782
E P C++ N PT+ T ++ T L+ VI LF +L I+
Sbjct: 211 DRECHPCHPNCTQGCNG-PTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLF--ILVIV 267
Query: 783 GYNF----RQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGML 838
G F R+K+ KK A++ + E EPL P+ PN A+LRI+KE EL+R +L
Sbjct: 268 GLTFAVYVRRKSIKKKRALRRFLET---ELVEPLTPSGTAPNQAQLRILKETELKRVKVL 324
Query: 839 GFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLL 898
G GAFG VYKG+WVPEGE VKIPVAIK+L ETTG + EF++EA IMAS++HP+L++LL
Sbjct: 325 GSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLL 384
Query: 899 AVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDL 958
VC++ + L+TQLMP GCL++YV HK+ IGS+ LNWC QIA+GM YLEE+RLVHRDL
Sbjct: 385 GVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDL 444
Query: 959 AARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVW 1018
AARNVLV++PN VKITDFGLA+LL+ +E EY A GGKMPIKW+ALECI +R FTH+SDVW
Sbjct: 445 AARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVW 504
Query: 1019 AFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSR 1078
++GVTIWE++++G +PY+ I R +P+L+E G +LPQP ICT+D+Y VMV CWM+DADSR
Sbjct: 505 SYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSR 564
Query: 1079 PTFKQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDAD 1138
P FK+LA F+ MARDP RYLVI GD M+LPS ++ + +NL E E ++DA+
Sbjct: 565 PKFKELAAEFSRMARDPQRYLVIQGDDRMKLPS---PNDSKFFQNLLDE-EDLEDMMDAE 620
Query: 1139 EYLQPKFKSMTGTVTTNSA 1157
EYL P+ ++ + T+ A
Sbjct: 621 EYLVPQAFNIPPPIYTSRA 639
Score = 157 bits (382), Expect = 2e-37
Identities = 76/197 (38%), Positives = 109/197 (55%), Gaps = 11/197 (5%)
Query: 362 YLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXXXXXXX-VNSGAI 420
+LN+Q+ PN T S F NL IGGR + L SL I+K +++G I
Sbjct: 1 FLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGL--SLLILKQQGITSLQFQSLKEISAGNI 58
Query: 421 AIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQCSADGCWGPGPD 480
I +N NLCY I W L + + + +I+ N C +VC+ CS+DGCWGPGPD
Sbjct: 59 YITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPD 118
Query: 481 QCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSEC---LDG---CTGASRANCT 532
QCLSC+ ++ G ICI++C+++ G ++ + C +C +C DG C G NCT
Sbjct: 119 QCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCT 178
Query: 533 SCKHVRDGPYCVAQCPE 549
C H +DGP CV +CP+
Sbjct: 179 KCSHFKDGPNCVEKCPD 195
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 14/94 (14%)
Query: 452 NGDPRQCEKNNLV--CDPQCSA--DG---CWGPGPDQCLSCQNYNFGEICIDNC-----S 499
+G+ R+ E ++ CDPQC DG C GPGPD C C ++ G C++ C
Sbjct: 140 DGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQG 199
Query: 500 VHPGLYK-AD-HKSCKQCHSECLDGCTGASRANC 531
+ ++K AD + C CH C GC G + +C
Sbjct: 200 ANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 233
Score = 59.3 bits (137), Expect = 1e-07
Identities = 64/242 (26%), Positives = 96/242 (39%), Gaps = 42/242 (17%)
Query: 64 VLPQLQIIRGRTLFKLNVREEEFALLVTMSTAFT-LELPALRDVLQGSVGIYSNFNLCHV 122
V L I GR L+ +LL+ T L+ +L+++ G++ I N NLC+
Sbjct: 16 VFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYY 69
Query: 123 KTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCA 182
TINW + F+ I N R+V + R A ENC +C+ C+
Sbjct: 70 HTINWTTL--------FSTI-------NQRIVIRDNRKA-----ENCTA-EGMVCNHLCS 108
Query: 183 QGRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQ---ECPSMQIYNPT 236
C+GP P C C F G C R F + C + +C M+ T
Sbjct: 109 SDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLT 168
Query: 237 TYSWEPNPNGKYAY---GATCVRNCPEHLLKDNGACVRSCPPNKTAVNGECIPCVGTCPK 293
+ P+ K ++ G CV CP+ L N + P++ EC PC C +
Sbjct: 169 CHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDR-----ECHPCHPNCTQ 223
Query: 294 TC 295
C
Sbjct: 224 GC 225
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 629 CRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-----SDHFTDEIG---RNCTP 680
C K + C G G C C+ FK G C ++CP ++ F + R C P
Sbjct: 159 CEKMEDGLLTCHGPGPDN--CTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHP 216
Query: 681 CHSEC-KGCTGPGPTDCI 697
CH C +GC GP DCI
Sbjct: 217 CHPNCTQGCNGPTSHDCI 234
>X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor
receptor protein.
Length = 1210
Score = 472 bits (1164), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCKLLEGEPREFVENSEC 555
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 603
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 604 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 663
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 664 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 721
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 722 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 781
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 782 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 841
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 842 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 901
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 902 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 961
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 962 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 1017
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 1018 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 1049
Score = 397 bits (977), Expect = e-109
Identities = 221/567 (38%), Positives = 306/567 (53%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C + G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCKLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 67.7 bits (158), Expect = 3e-10
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 53/308 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCKLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAVNG 282
C + CP+ + T W+ G + C NC G + CP NG
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCP-----TNG 640
Query: 283 ECIPCVGT 290
IP + T
Sbjct: 641 PKIPSIAT 648
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 636
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
>BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein.
Length = 1091
Score = 472 bits (1163), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 451 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 510
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 511 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 558
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 559 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 618
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 619 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 676
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 677 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 736
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 737 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 796
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 797 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 856
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 857 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 916
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 917 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 972
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 973 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 1004
Score = 332 bits (817), Expect = 4e-90
Identities = 166/409 (40%), Positives = 221/409 (54%), Gaps = 32/409 (7%)
Query: 160 WAAGESIENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYD 219
W AGE ENCQK +K IC+ QC+ GRC G +P DCC+ CA GCTGP + CL CR F D
Sbjct: 155 WGAGE--ENCQKLTKIICAQQCS-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRD 211
Query: 220 EGTCSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKT 278
E TC CP + +YNPTTY + NP GKY++GATCV+ CP +++ D+G+CVR+C +
Sbjct: 212 EATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSY 271
Query: 279 AVNGE----CIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTF 326
+ + C C G C K C + I++ NI FK+CT I G + IL + F
Sbjct: 272 EMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAF 331
Query: 327 TGFQQVNQDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGG 386
G SF P ++P L++ TV+E+TG+L +QA N T L F NLE+I G
Sbjct: 332 RG-------DSF-THTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRG 383
Query: 387 RQVVENLFASLYIVKTXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHK 446
R F SL +V ++ G + I N+NLCYA+ I W KL + K
Sbjct: 384 RTKQHGQF-SLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQK 442
Query: 447 QIIQKNGDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK 506
I N C+ VC CS +GCWGP P C+SC+N + G C+D C++ G +
Sbjct: 443 TKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPR 502
Query: 507 --ADHKSCKQCHSECLD-----GCTGASRANCTSCKHVRDGPYCVAQCP 548
++ C QCH ECL CTG NC C H DGP+CV CP
Sbjct: 503 EFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP 551
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 314 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 373
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 374 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 428
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 429 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 467
Query: 184 GRCFGPNPRDC--CNTFCAG-GCTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 468 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 527
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 528 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 562
Score = 66.5 bits (155), Expect = 6e-10
Identities = 34/71 (47%), Positives = 48/71 (67%), Gaps = 1/71 (1%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFK 78
LQIIRG ++
Sbjct: 104 LQIIRGNMYYE 114
Score = 60.1 bits (139), Expect = 6e-08
Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 8/84 (9%)
Query: 465 CDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGCT 524
CDP C CWG G + C IC CS G + S CH++C GCT
Sbjct: 145 CDPSCPNGSCWGAGEENCQKLTKI----ICAQQCS---GRCRGKSPS-DCCHNQCAAGCT 196
Query: 525 GASRANCTSCKHVRDGPYCVAQCP 548
G ++C C+ RD C CP
Sbjct: 197 GPRESDCLVCRKFRDEATCKDTCP 220
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 499 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 558
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 559 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 591
Score = 46.0 bits (104), Expect = 0.001
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 20/97 (20%)
Query: 630 RKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK-GC 688
+KC P C +G E+ CQ QC C +D C CH++C GC
Sbjct: 143 QKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAAGC 195
Query: 689 TGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
TGP +DC+ C+ + DE C DTCP
Sbjct: 196 TGPRESDCLVCRKFR---------DE---ATCKDTCP 220
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 500 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 557
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 558 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 591
>AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor
receptor (erythroblastic leukemia viral (v-erb-b) oncog
protein.
Length = 1210
Score = 472 bits (1163), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 603
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 604 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 663
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 664 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 721
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 722 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 781
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 782 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 841
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 842 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 901
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 902 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 961
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 962 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 1017
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 1018 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 1049
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 67.7 bits (158), Expect = 3e-10
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 53/308 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAVNG 282
C + CP+ + T W+ G + C NC G + CP NG
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCP-----TNG 640
Query: 283 ECIPCVGT 290
IP + T
Sbjct: 641 PKIPSIAT 648
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 636
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
>AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting
protein 40 protein.
Length = 1210
Score = 472 bits (1163), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 603
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 604 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 663
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 664 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 721
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 722 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 781
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 782 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 841
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 842 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 901
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 902 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 961
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 962 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 1017
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 1018 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 1049
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 67.7 bits (158), Expect = 3e-10
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 53/308 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAVNG 282
C + CP+ + T W+ G + C NC G + CP NG
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCP-----TNG 640
Query: 283 ECIPCVGT 290
IP + T
Sbjct: 641 PKIPSIAT 648
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 636
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
>AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth factor
receptor protein.
Length = 1210
Score = 472 bits (1163), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 603
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 604 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 663
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 664 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 721
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 722 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 781
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 782 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 841
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 842 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 901
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 902 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 961
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 962 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 1017
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 1018 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 1049
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 67.7 bits (158), Expect = 3e-10
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 53/308 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAVNG 282
C + CP+ + T W+ G + C NC G + CP NG
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCP-----TNG 640
Query: 283 ECIPCVGT 290
IP + T
Sbjct: 641 PKIPSIAT 648
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 636
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
>AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor
receptor isoform a variant protein.
Length = 1081
Score = 472 bits (1163), Expect = e-132
Identities = 253/572 (44%), Positives = 344/572 (60%), Gaps = 39/572 (6%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 367 ENSCKATGQVCHALCSPEGCWGPEPKDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 426
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 427 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 474
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 475 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 534
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 535 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 592
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 593 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 652
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 653 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 712
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 713 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 772
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+Y +MV CWM+DADSRP F
Sbjct: 773 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKF 832
Query: 1082 KQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYL 1141
++L F++MARDP RYLVI GD+ M LPS + R L E + +VDADEYL
Sbjct: 833 RELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRALMDE-EDMDDVVDADEYL 888
Query: 1142 QPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
P+ + T+ + L + + T +S C
Sbjct: 889 IPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 920
Score = 333 bits (819), Expect = 2e-90
Identities = 177/452 (39%), Positives = 241/452 (53%), Gaps = 37/452 (8%)
Query: 121 HVKTINW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTI 176
HV++I W D ++ D L+ ++ F LG + P + W AGE ENCQK +K I
Sbjct: 29 HVESIQWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKII 85
Query: 177 CSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPT 236
C+ QC+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPT
Sbjct: 86 CAQQCS-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPT 144
Query: 237 TYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTC 291
TY + NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C
Sbjct: 145 TYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPC 204
Query: 292 PKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYP 343
K C + I++ NI FK+CT I G + IL + F G SF P
Sbjct: 205 RKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTP 256
Query: 344 KMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTX 403
++P L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 257 PLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLN 315
Query: 404 XXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
++ G + I N+NLCYA+ I W KL + K I N C+
Sbjct: 316 ITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQ 375
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD 521
VC CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 376 VCHALCSPEGCWGPEPKDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLP 435
Query: 522 -----GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 436 QAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP 467
Score = 70.1 bits (164), Expect = 5e-11
Identities = 73/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 230 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 289
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 290 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 344
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 345 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 383
Query: 184 GRCFGPNPRDC--CNTFCAG-GCTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP P+DC C G C R F + C Q P Q N T
Sbjct: 384 EGCWGPEPKDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 443
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 444 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 478
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 415 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 474
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 475 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 507
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 57 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 109
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 110 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 136
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 416 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 473
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 474 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 507
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 458 bits (1130), Expect = e-128
Identities = 235/537 (43%), Positives = 332/537 (61%), Gaps = 44/537 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC------PSDHFTDEIGRNCTPCHSEC 685
CH LC + +G C C+ F RG +C +EC P ++ R+C PCH EC
Sbjct: 511 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVN---ARHCLPCHPEC 567
Query: 686 KG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQ 739
+ C GP C+ C + K + PF C CP + + + +
Sbjct: 568 QPQNGSVTCFGPEADQCVACAHYK-----------DPPF-CVARCPSGVKPDLSYMPIWK 615
Query: 740 DPIEE------PY-CSEHANDIPT----ATARTSTVLVIILVIASLFLAVLAIIGYNFRQ 788
P EE P C+ D+ A R S + II + + L V+ + +
Sbjct: 616 FPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILI 675
Query: 789 KAKAKK-EAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
K + +K M +L E EPL P+ PN A++RI+KE ELR+ +LG GAFG VY
Sbjct: 676 KRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVY 735
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KG+W+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +LL +C+T+ +
Sbjct: 736 KGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ 795
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQLMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRDLAARNVLV++
Sbjct: 796 LVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKS 855
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
PN VKITDFGLA+LLDI+E EY A GGK+PIKW+ALE I R FTH+SDVW++GVT+WE+
Sbjct: 856 PNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWEL 915
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA+PY+ I AR +P+L+E G +LPQP ICT+D+Y +MV CWM+D++ RP F++L
Sbjct: 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPK 1144
F+ MARDP R++VI + + + ++ + + LVDA+EYL P+
Sbjct: 976 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLED-----DDMGDLVDAEEYLVPQ 1027
Score = 337 bits (829), Expect = 1e-91
Identities = 200/583 (34%), Positives = 291/583 (49%), Gaps = 49/583 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+ +P++ +TH LR + C V GNLELT+L + LSFL+ I+EV GYVLI+H +V
Sbjct: 33 LRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNA-SLSFLQDIQEVQGYVLIAHNQV 91
Query: 61 HKIVLPQLQIIRGRTLFKLN----VREEEFALLVTMSTAFT-------LELPALRDVLQG 109
++ L +L+I+RG LF+ N V + L T L+L +L ++L+G
Sbjct: 92 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 151
Query: 110 SVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPAR-WAAGESI 166
V I N LC+ TI W +I Q+ T I + + + +R W GES
Sbjct: 152 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCW--GESS 209
Query: 167 ENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQE 226
E+CQ ++T+C+ CA RC GP P DCC+ CA GCTGP + CLAC +F G C
Sbjct: 210 EDCQSLTRTVCAGGCA--RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 267
Query: 227 CPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE-- 283
CP++ YN T+ PNP G+Y +GA+CV CP +L D G+C CP + V E
Sbjct: 268 CPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDG 327
Query: 284 ---CIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQV 332
C C C + C R + + S NI F C I GS+ L +F G
Sbjct: 328 TQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPAS 387
Query: 333 NQDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVEN 392
N ++P+ L+VF T+ E+TGYL + A + LS F+NL+VI GR ++ N
Sbjct: 388 NT--------APLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGR-ILHN 438
Query: 393 LFASLYIVKTXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKN 452
SL + + SG I N +LC+ + W++L ++ + N
Sbjct: 439 GAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTAN 498
Query: 453 GDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHK 510
+C L C C+ CWGPGP QC++C + G+ C++ C V GL + + +
Sbjct: 499 RPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNAR 558
Query: 511 SCKQCHSEC--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C CH EC +G C G C +C H +D P+CVA+CP
Sbjct: 559 HCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCP 601
Score = 56.8 bits (131), Expect = 5e-07
Identities = 62/212 (29%), Positives = 94/212 (44%), Gaps = 28/212 (13%)
Query: 40 LSFLKYIREVTGYVLIS---HVKVHKIVLPQLQIIRGRTLFKLNVREEEFALLVTMSTAF 96
L + + E+TGY+ IS V LQ+IRGR L ++L +
Sbjct: 397 LQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRIL-----HNGAYSLTLQGLGIS 451
Query: 97 TLELPALRDVLQGSVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILP----LGKGNA- 151
L L +LR++ G I+ N +LC V T+ WD++ ++ Q P +G+G A
Sbjct: 452 WLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLAC 511
Query: 152 -RVVTQPARWAAGES-IENCQKFSK-TICSPQCA--QG--RCFGPNPRDC--CNTFCA-- 200
++ + W G + NC +F + C +C QG R + N R C C+ C
Sbjct: 512 HQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREY-VNARHCLPCHPECQPQ 570
Query: 201 -GG--CTGPLPTQCLACRNFYDEGTCSQECPS 229
G C GP QC+AC ++ D C CPS
Sbjct: 571 NGSVTCFGPEADQCVACAHYKDPPFCVARCPS 602
Score = 38.3 bits (85), Expect = 0.19
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 630 RKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK-GC 688
R CHP C G + + C R C C + +C CH +C GC
Sbjct: 190 RACHPCSPMCKGSRCWGESSEDCQSLTR-TVCAGGCA--RCKGPLPTDC--CHEQCAAGC 244
Query: 689 TGPGPTDCIKC 699
TGP +DC+ C
Sbjct: 245 TGPKHSDCLAC 255
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 458 bits (1130), Expect = e-128
Identities = 235/537 (43%), Positives = 332/537 (61%), Gaps = 44/537 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC------PSDHFTDEIGRNCTPCHSEC 685
CH LC + +G C C+ F RG +C +EC P ++ R+C PCH EC
Sbjct: 511 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVN---ARHCLPCHPEC 567
Query: 686 KG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQ 739
+ C GP C+ C + K + PF C CP + + + +
Sbjct: 568 QPQNGSVTCFGPEADQCVACAHYK-----------DPPF-CVARCPSGVKPDLSYMPIWK 615
Query: 740 DPIEE------PY-CSEHANDIPT----ATARTSTVLVIILVIASLFLAVLAIIGYNFRQ 788
P EE P C+ D+ A R S + II + + L V+ + +
Sbjct: 616 FPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVGILLVVVLGVVFGILI 675
Query: 789 KAKAKK-EAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
K + +K M +L E EPL P+ PN A++RI+KE ELR+ +LG GAFG VY
Sbjct: 676 KRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVY 735
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KG+W+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +LL +C+T+ +
Sbjct: 736 KGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ 795
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQLMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRDLAARNVLV++
Sbjct: 796 LVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKS 855
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
PN VKITDFGLA+LLDI+E EY A GGK+PIKW+ALE I R FTH+SDVW++GVT+WE+
Sbjct: 856 PNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWEL 915
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA+PY+ I AR +P+L+E G +LPQP ICT+D+Y +MV CWM+D++ RP F++L
Sbjct: 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPK 1144
F+ MARDP R++VI + + + ++ + + LVDA+EYL P+
Sbjct: 976 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLED-----DDMGDLVDAEEYLVPQ 1027
Score = 337 bits (829), Expect = 1e-91
Identities = 200/583 (34%), Positives = 291/583 (49%), Gaps = 49/583 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+ +P++ +TH LR + C V GNLELT+L + LSFL+ I+EV GYVLI+H +V
Sbjct: 33 LRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNA-SLSFLQDIQEVQGYVLIAHNQV 91
Query: 61 HKIVLPQLQIIRGRTLFKLN----VREEEFALLVTMSTAFT-------LELPALRDVLQG 109
++ L +L+I+RG LF+ N V + L T L+L +L ++L+G
Sbjct: 92 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 151
Query: 110 SVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPAR-WAAGESI 166
V I N LC+ TI W +I Q+ T I + + + +R W GES
Sbjct: 152 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCW--GESS 209
Query: 167 ENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQE 226
E+CQ ++T+C+ CA RC GP P DCC+ CA GCTGP + CLAC +F G C
Sbjct: 210 EDCQSLTRTVCAGGCA--RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 267
Query: 227 CPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE-- 283
CP++ YN T+ PNP G+Y +GA+CV CP +L D G+C CP + V E
Sbjct: 268 CPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDG 327
Query: 284 ---CIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQV 332
C C C + C R + + S NI F C I GS+ L +F G
Sbjct: 328 TQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPAS 387
Query: 333 NQDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVEN 392
N ++P+ L+VF T+ E+TGYL + A + LS F+NL+VI GR ++ N
Sbjct: 388 NT--------APLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGR-ILHN 438
Query: 393 LFASLYIVKTXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKN 452
SL + + SG I N +LC+ + W++L ++ + N
Sbjct: 439 GAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTAN 498
Query: 453 GDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHK 510
+C L C C+ CWGPGP QC++C + G+ C++ C V GL + + +
Sbjct: 499 RPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNAR 558
Query: 511 SCKQCHSEC--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C CH EC +G C G C +C H +D P+CVA+CP
Sbjct: 559 HCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCP 601
Score = 56.8 bits (131), Expect = 5e-07
Identities = 62/212 (29%), Positives = 94/212 (44%), Gaps = 28/212 (13%)
Query: 40 LSFLKYIREVTGYVLIS---HVKVHKIVLPQLQIIRGRTLFKLNVREEEFALLVTMSTAF 96
L + + E+TGY+ IS V LQ+IRGR L ++L +
Sbjct: 397 LQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRIL-----HNGAYSLTLQGLGIS 451
Query: 97 TLELPALRDVLQGSVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILP----LGKGNA- 151
L L +LR++ G I+ N +LC V T+ WD++ ++ Q P +G+G A
Sbjct: 452 WLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLAC 511
Query: 152 -RVVTQPARWAAGES-IENCQKFSK-TICSPQCA--QG--RCFGPNPRDC--CNTFCA-- 200
++ + W G + NC +F + C +C QG R + N R C C+ C
Sbjct: 512 HQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREY-VNARHCLPCHPECQPQ 570
Query: 201 -GG--CTGPLPTQCLACRNFYDEGTCSQECPS 229
G C GP QC+AC ++ D C CPS
Sbjct: 571 NGSVTCFGPEADQCVACAHYKDPPFCVARCPS 602
Score = 38.3 bits (85), Expect = 0.19
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 630 RKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK-GC 688
R CHP C G + + C R C C + +C CH +C GC
Sbjct: 190 RACHPCSPMCKGSRCWGESSEDCQSLTR-TVCAGGCA--RCKGPLPTDC--CHEQCAAGC 244
Query: 689 TGPGPTDCIKC 699
TGP +DC+ C
Sbjct: 245 TGPKHSDCLAC 255
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 458 bits (1129), Expect = e-128
Identities = 234/537 (43%), Positives = 332/537 (61%), Gaps = 44/537 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC------PSDHFTDEIGRNCTPCHSEC 685
CH LC + +G C C+ F RG +C +EC P ++ R+C PCH EC
Sbjct: 511 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVN---ARHCLPCHPEC 567
Query: 686 KG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQ 739
+ C GP C+ C + K + PF C CP + + + +
Sbjct: 568 QPQNGSVTCFGPEADQCVACAHYK-----------DPPF-CVARCPSGVKPDLSYMPIWK 615
Query: 740 DPIEE------PY-CSEHANDIPT----ATARTSTVLVIILVIASLFLAVLAIIGYNFRQ 788
P EE P C+ D+ A R S + I+ + + L V+ + +
Sbjct: 616 FPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIVSAVVGILLVVVLGVVFGILI 675
Query: 789 KAKAKK-EAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
K + +K M +L E EPL P+ PN A++RI+KE ELR+ +LG GAFG VY
Sbjct: 676 KRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVY 735
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KG+W+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +LL +C+T+ +
Sbjct: 736 KGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQ 795
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQLMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRDLAARNVLV++
Sbjct: 796 LVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKS 855
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
PN VKITDFGLA+LLDI+E EY A GGK+PIKW+ALE I R FTH+SDVW++GVT+WE+
Sbjct: 856 PNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWEL 915
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA+PY+ I AR +P+L+E G +LPQP ICT+D+Y +MV CWM+D++ RP F++L
Sbjct: 916 MTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSE 975
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPK 1144
F+ MARDP R++VI + + + ++ + + LVDA+EYL P+
Sbjct: 976 FSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLED-----DDMGDLVDAEEYLVPQ 1027
Score = 337 bits (829), Expect = 1e-91
Identities = 200/583 (34%), Positives = 291/583 (49%), Gaps = 49/583 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+ +P++ +TH LR + C V GNLELT+L + LSFL+ I+EV GYVLI+H +V
Sbjct: 33 LRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNA-SLSFLQDIQEVQGYVLIAHNQV 91
Query: 61 HKIVLPQLQIIRGRTLFKLN----VREEEFALLVTMSTAFT-------LELPALRDVLQG 109
++ L +L+I+RG LF+ N V + L T L+L +L ++L+G
Sbjct: 92 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 151
Query: 110 SVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPAR-WAAGESI 166
V I N LC+ TI W +I Q+ T I + + + +R W GES
Sbjct: 152 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCW--GESS 209
Query: 167 ENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQE 226
E+CQ ++T+C+ CA RC GP P DCC+ CA GCTGP + CLAC +F G C
Sbjct: 210 EDCQSLTRTVCAGGCA--RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 267
Query: 227 CPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE-- 283
CP++ YN T+ PNP G+Y +GA+CV CP +L D G+C CP + V E
Sbjct: 268 CPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDG 327
Query: 284 ---CIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQV 332
C C C + C R + + S NI F C I GS+ L +F G
Sbjct: 328 TQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPAS 387
Query: 333 NQDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVEN 392
N ++P+ L+VF T+ E+TGYL + A + LS F+NL+VI GR ++ N
Sbjct: 388 NT--------APLQPEQLQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGR-ILHN 438
Query: 393 LFASLYIVKTXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKN 452
SL + + SG I N +LC+ + W++L ++ + N
Sbjct: 439 GAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTAN 498
Query: 453 GDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHK 510
+C L C C+ CWGPGP QC++C + G+ C++ C V GL + + +
Sbjct: 499 RPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNAR 558
Query: 511 SCKQCHSEC--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C CH EC +G C G C +C H +D P+CVA+CP
Sbjct: 559 HCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCP 601
Score = 56.8 bits (131), Expect = 5e-07
Identities = 62/212 (29%), Positives = 94/212 (44%), Gaps = 28/212 (13%)
Query: 40 LSFLKYIREVTGYVLIS---HVKVHKIVLPQLQIIRGRTLFKLNVREEEFALLVTMSTAF 96
L + + E+TGY+ IS V LQ+IRGR L ++L +
Sbjct: 397 LQVFETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRIL-----HNGAYSLTLQGLGIS 451
Query: 97 TLELPALRDVLQGSVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILP----LGKGNA- 151
L L +LR++ G I+ N +LC V T+ WD++ ++ Q P +G+G A
Sbjct: 452 WLGLRSLRELGSGLALIHHNTHLCFVHTVPWDQLFRNPHQALLHTANRPEDECVGEGLAC 511
Query: 152 -RVVTQPARWAAGES-IENCQKFSK-TICSPQCA--QG--RCFGPNPRDC--CNTFCA-- 200
++ + W G + NC +F + C +C QG R + N R C C+ C
Sbjct: 512 HQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREY-VNARHCLPCHPECQPQ 570
Query: 201 -GG--CTGPLPTQCLACRNFYDEGTCSQECPS 229
G C GP QC+AC ++ D C CPS
Sbjct: 571 NGSVTCFGPEADQCVACAHYKDPPFCVARCPS 602
Score = 38.3 bits (85), Expect = 0.19
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 630 RKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK-GC 688
R CHP C G + + C R C C + +C CH +C GC
Sbjct: 190 RACHPCSPMCKGSRCWGESSEDCQSLTR-TVCAGGCA--RCKGPLPTDC--CHEQCAAGC 244
Query: 689 TGPGPTDCIKC 699
TGP +DC+ C
Sbjct: 245 TGPKHSDCLAC 255
>M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (ERBB3) mRNA, complete cds. ).
Length = 1342
Score = 423 bits (1042), Expect = e-117
Identities = 222/575 (38%), Positives = 314/575 (54%), Gaps = 47/575 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+SV + + Y+ L + C V GNLE+ L + DLSFL++IREVTGYVL++ +
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMS-------TAFTLELPALRDVLQGSVGI 113
+ LP L+++RG ++ + +FA+ V ++ L L L ++L G V I
Sbjct: 95 STLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYI 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPARWAAGESIENCQK 171
N LCH+ TI+W +I +D ++ G+ V + W G E+CQ
Sbjct: 150 EKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKGRCWGPGS--EDCQT 204
Query: 172 FSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQ 231
+KTIC+PQC G CFGPNP CC+ CAGGC+GP T C ACR+F D G C CP
Sbjct: 205 LTKTICAPQC-NGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPL 263
Query: 232 IYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPC 287
+YN T+ EPNP+ KY YG CV +CP + + D +CVR+CPP+K V NG C PC
Sbjct: 264 VYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPC 323
Query: 288 VGTCPKTCRAE------KPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGER 341
G CPK C + + S NID F +CT I G+++ L TG +N D +
Sbjct: 324 GGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFL---ITG---LNGDP--WHK 375
Query: 342 YPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVK 401
P ++P+ L VF TVRE+TGYLN+Q+ P+ + S F NL IGGR + F+ L +
Sbjct: 376 IPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKN 435
Query: 402 TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQ-CEK 460
+++G I I NR LCY + W K+++ +++ K+ PR+ C
Sbjct: 436 LNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVA 495
Query: 461 NNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSE 518
VCDP CS+ GCWGPGP QCLSC+NY+ G +C+ +C+ G + A C CH E
Sbjct: 496 EGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPE 555
Query: 519 C--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C ++G C G+ C C H RDGP+CV+ CP
Sbjct: 556 CQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCP 590
Score = 346 bits (851), Expect = 3e-94
Identities = 206/583 (35%), Positives = 307/583 (52%), Gaps = 48/583 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC-----PSDHFTDEIGRNCTPCHSECK 686
C PLC +G C C + RG C C F E C CH EC+
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEA--ECFSCHPECQ 557
Query: 687 G------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNI---PNKIYFDEQ 737
C G G C +C + + + P +C +CP + IY
Sbjct: 558 PMEGTATCNGSGSDTCAQCAHFR-----------DGP-HCVSSCPHGVLGAKGPIYKYPD 605
Query: 738 LQDPIEEPY--CSEHANDIPTATARTSTVLVI--------ILVIASLFLAVLAIIGYNFR 787
+Q+ + C++ T+++I + VIA L + + + G
Sbjct: 606 VQNECRPCHENCTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLY 665
Query: 788 QKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
+ + + M L E EPL P+ K N RI KE ELR+ +LG G FG V+
Sbjct: 666 WRGRRIQNKRAMRRYLERGESIEPLDPSE-KANKVLARIFKETELRKLKVLGSGVFGTVH 724
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KGVW+PEGE++KIPV IKV+++ +G + + + + S++H ++++LL +C + +
Sbjct: 725 KGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQ 784
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQ +PLG L+D+VR H+ +G + LNW QIA+GM YLEE +VHR+LAARNVL+++
Sbjct: 785 LVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKS 844
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
P+ V++ DFG+A LL ++ + + K PIKW+ALE I +TH+SDVW++GVT+WE+
Sbjct: 845 PSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWEL 904
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA PY + VP+L+E G +L QP ICT+D+Y VMV CWM+D + RPTFK+LA+
Sbjct: 905 MTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANE 964
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPKFKS 1147
F MARDP RYLVI + P + E + N E +D D L+ + +
Sbjct: 965 FTRMARDPPRYLVIKRESG---PGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDN 1021
Query: 1148 MTGTVTTNSALSAGMET-----QTSSLKPCTSSSWPNNAGQDG 1185
+ T T SALS + T + SL +S P N G G
Sbjct: 1022 L-ATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLG 1063
Score = 99 bits (238), Expect = 6e-20
Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXX 409
L +REVTGY+ V + F++L NL V+ G QV + FA ++
Sbjct: 74 LSFLQWIREVTGYVLVAMNE--FSTLP-LPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHA 130
Query: 410 ------XXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
+ SG + I +N LC+ D I W +V+ +D + +++ NG R C +
Sbjct: 131 LRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG--RSCPPCHE 188
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
VC +C WGPG + C + IC C+ H + + C CH EC GC
Sbjct: 189 VCKGRC-----WGPGSEDCQTLTK----TICAPQCNGH--CFGPNPNQC--CHDECAGGC 235
Query: 524 TGASRANCTSCKHVRDGPYCVAQCPE 549
+G +C +C+H D CV +CP+
Sbjct: 236 SGPQDTDCFACRHFNDSGACVPRCPQ 261
Score = 50.4 bits (115), Expect = 4e-05
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 452 NGDPRQC--EKNNLVCDPQCSA-DG---CWGPGPDQCLSCQNYNFGEICIDNC-----SV 500
NG+PR+ E C P+C +G C G G D C C ++ G C+ +C
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 501 HPGLYKAD--HKSCKQCHSECLDGCTGASRANC 531
+YK C+ CH C GC G +C
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDC 629
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 617 NVKPLEGKVKIACRKCHPLCIKCVGF----GIHEQVCQVCNGFKRGDQCEDECPSD---- 668
N +P E + C CHP C G G C C F+ G C CP
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 669 ----HFTDEIGRNCTPCHSEC-KGCTGPGPTDCI 697
+ ++ C PCH C +GC GP DC+
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDCL 630
Score = 48.0 bits (109), Expect = 2e-04
Identities = 38/124 (30%), Positives = 52/124 (41%), Gaps = 23/124 (18%)
Query: 195 CNTFCA-GGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWEP-----NPNGKY 248
C+ C+ GGC GP P QCL+CRN+ G C C + P ++ E +P +
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLN-GEPREFAHEAECFSCHPECQP 558
Query: 249 AYG-ATCVRN----CPEHL-LKDNGACVRSCPPNKTAVNG----------ECIPCVGTCP 292
G ATC + C + +D CV SCP G EC PC C
Sbjct: 559 MEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCT 618
Query: 293 KTCR 296
+ C+
Sbjct: 619 QGCK 622
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 628 ACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK 686
+C CH +C +C G G + CQ QC C + C CH EC
Sbjct: 182 SCPPCHEVCKGRCWGPGSED--CQTLTKTICAPQCNGHCFGPN-----PNQC--CHDECA 232
Query: 687 G-CTGPGPTDCIKCKN 701
G C+GP TDC C++
Sbjct: 233 GGCSGPQDTDCFACRH 248
Score = 40.3 bits (90), Expect = 0.048
Identities = 15/23 (65%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 675 GRNCTPCHSECKG-CTGPGPTDC 696
GR+C PCH CKG C GPG DC
Sbjct: 180 GRSCPPCHEVCKGRCWGPGSEDC 202
Score = 33.1 bits (72), Expect = 7.2
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 1/27 (3%)
Query: 675 GRNCTPCHSECKGCTGPGPTDCIKCKN 701
G+ C P S GC GPGP C+ C+N
Sbjct: 497 GKVCDPLCSS-GGCWGPGPGQCLSCRN 522
>BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 1342
Score = 423 bits (1042), Expect = e-117
Identities = 222/575 (38%), Positives = 314/575 (54%), Gaps = 47/575 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+SV + + Y+ L + C V GNLE+ L + DLSFL++IREVTGYVL++ +
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMS-------TAFTLELPALRDVLQGSVGI 113
+ LP L+++RG ++ + +FA+ V ++ L L L ++L G V I
Sbjct: 95 STLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYI 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPARWAAGESIENCQK 171
N LCH+ TI+W +I +D ++ G+ V + W G E+CQ
Sbjct: 150 EKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKGRCWGPGS--EDCQT 204
Query: 172 FSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQ 231
+KTIC+PQC G CFGPNP CC+ CAGGC+GP T C ACR+F D G C CP
Sbjct: 205 LTKTICAPQC-NGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPL 263
Query: 232 IYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPC 287
+YN T+ EPNP+ KY YG CV +CP + + D +CVR+CPP+K V NG C PC
Sbjct: 264 VYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPC 323
Query: 288 VGTCPKTCRAE------KPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGER 341
G CPK C + + S NID F +CT I G+++ L TG +N D +
Sbjct: 324 GGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFL---ITG---LNGDP--WHK 375
Query: 342 YPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVK 401
P ++P+ L VF TVRE+TGYLN+Q+ P+ + S F NL IGGR + F+ L +
Sbjct: 376 IPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKN 435
Query: 402 TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQ-CEK 460
+++G I I NR LCY + W K+++ +++ K+ PR+ C
Sbjct: 436 LNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVA 495
Query: 461 NNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSE 518
VCDP CS+ GCWGPGP QCLSC+NY+ G +C+ +C+ G + A C CH E
Sbjct: 496 EGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPE 555
Query: 519 C--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C ++G C G+ C C H RDGP+CV+ CP
Sbjct: 556 CQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCP 590
Score = 346 bits (851), Expect = 3e-94
Identities = 206/583 (35%), Positives = 307/583 (52%), Gaps = 48/583 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC-----PSDHFTDEIGRNCTPCHSECK 686
C PLC +G C C + RG C C F E C CH EC+
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEA--ECFSCHPECQ 557
Query: 687 G------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNI---PNKIYFDEQ 737
C G G C +C + + + P +C +CP + IY
Sbjct: 558 PMEGTATCNGSGSDTCAQCAHFR-----------DGP-HCVSSCPHGVLGAKGPIYKYPD 605
Query: 738 LQDPIEEPY--CSEHANDIPTATARTSTVLVI--------ILVIASLFLAVLAIIGYNFR 787
+Q+ + C++ T+++I + VIA L + + + G
Sbjct: 606 VQNECRPCHENCTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLY 665
Query: 788 QKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
+ + + M L E EPL P+ K N RI KE ELR+ +LG G FG V+
Sbjct: 666 WRGRRIQNKRAMRRYLERGESIEPLDPSE-KANKVLARIFKETELRKLKVLGSGVFGTVH 724
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KGVW+PEGE++KIPV IKV+++ +G + + + + S++H ++++LL +C + +
Sbjct: 725 KGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQ 784
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQ +PLG L+D+VR H+ +G + LNW QIA+GM YLEE +VHR+LAARNVL+++
Sbjct: 785 LVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKS 844
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
P+ V++ DFG+A LL ++ + + K PIKW+ALE I +TH+SDVW++GVT+WE+
Sbjct: 845 PSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWEL 904
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA PY + VP+L+E G +L QP ICT+D+Y VMV CWM+D + RPTFK+LA+
Sbjct: 905 MTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANE 964
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPKFKS 1147
F MARDP RYLVI + P + E + N E +D D L+ + +
Sbjct: 965 FTRMARDPPRYLVIKRESG---PGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDN 1021
Query: 1148 MTGTVTTNSALSAGMET-----QTSSLKPCTSSSWPNNAGQDG 1185
+ T T SALS + T + SL +S P N G G
Sbjct: 1022 L-ATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLG 1063
Score = 99 bits (238), Expect = 6e-20
Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXX 409
L +REVTGY+ V + F++L NL V+ G QV + FA ++
Sbjct: 74 LSFLQWIREVTGYVLVAMNE--FSTLP-LPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHA 130
Query: 410 ------XXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
+ SG + I +N LC+ D I W +V+ +D + +++ NG R C +
Sbjct: 131 LRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG--RSCPPCHE 188
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
VC +C WGPG + C + IC C+ H + + C CH EC GC
Sbjct: 189 VCKGRC-----WGPGSEDCQTLTK----TICAPQCNGH--CFGPNPNQC--CHDECAGGC 235
Query: 524 TGASRANCTSCKHVRDGPYCVAQCPE 549
+G +C +C+H D CV +CP+
Sbjct: 236 SGPQDTDCFACRHFNDSGACVPRCPQ 261
Score = 50.4 bits (115), Expect = 4e-05
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 13/93 (13%)
Query: 452 NGDPRQC--EKNNLVCDPQCSA-DG---CWGPGPDQCLSCQNYNFGEICIDNC-----SV 500
NG+PR+ E C P+C +G C G G D C C ++ G C+ +C
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 501 HPGLYKAD--HKSCKQCHSECLDGCTGASRANC 531
+YK C+ CH C GC G +C
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDC 629
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 617 NVKPLEGKVKIACRKCHPLCIKCVGF----GIHEQVCQVCNGFKRGDQCEDECPSD---- 668
N +P E + C CHP C G G C C F+ G C CP
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 669 ----HFTDEIGRNCTPCHSEC-KGCTGPGPTDCI 697
+ ++ C PCH C +GC GP DC+
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDCL 630
Score = 48.0 bits (109), Expect = 2e-04
Identities = 38/124 (30%), Positives = 52/124 (41%), Gaps = 23/124 (18%)
Query: 195 CNTFCA-GGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWEP-----NPNGKY 248
C+ C+ GGC GP P QCL+CRN+ G C C + P ++ E +P +
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLN-GEPREFAHEAECFSCHPECQP 558
Query: 249 AYG-ATCVRN----CPEHL-LKDNGACVRSCPPNKTAVNG----------ECIPCVGTCP 292
G ATC + C + +D CV SCP G EC PC C
Sbjct: 559 MEGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCT 618
Query: 293 KTCR 296
+ C+
Sbjct: 619 QGCK 622
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 628 ACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK 686
+C CH +C +C G G + CQ QC C + C CH EC
Sbjct: 182 SCPPCHEVCKGRCWGPGSED--CQTLTKTICAPQCNGHCFGPN-----PNQC--CHDECA 232
Query: 687 G-CTGPGPTDCIKCKN 701
G C+GP TDC C++
Sbjct: 233 GGCSGPQDTDCFACRH 248
Score = 40.3 bits (90), Expect = 0.048
Identities = 15/23 (65%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 675 GRNCTPCHSECKG-CTGPGPTDC 696
GR+C PCH CKG C GPG DC
Sbjct: 180 GRSCPPCHEVCKGRCWGPGSEDC 202
Score = 33.1 bits (72), Expect = 7.2
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 1/27 (3%)
Query: 675 GRNCTPCHSECKGCTGPGPTDCIKCKN 701
G+ C P S GC GPGP C+ C+N
Sbjct: 497 GKVCDPLCSS-GGCWGPGPGQCLSCRN 522
>M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (HER3) mRNA, complete cds. ).
Length = 1342
Score = 422 bits (1039), Expect = e-117
Identities = 222/575 (38%), Positives = 313/575 (54%), Gaps = 47/575 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+SV + + Y+ L + C V GNLE+ L + DLSFL++IREVTGYVL++ +
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMS-------TAFTLELPALRDVLQGSVGI 113
+ LP L+++RG ++ + +FA+ V ++ L L L ++L G V I
Sbjct: 95 STLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYI 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPARWAAGESIENCQK 171
N LCH+ TI+W +I +D ++ G+ V + W G E+CQ
Sbjct: 150 EKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKGRCWGPGS--EDCQT 204
Query: 172 FSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQ 231
+KTIC+PQC G CFGPNP CC+ CAGGC+GP T C ACR+F D G C CP
Sbjct: 205 LTKTICAPQC-NGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPL 263
Query: 232 IYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPC 287
+YN T+ EPNP+ KY YG CV +CP + + D +CVR+CPP+K V NG C PC
Sbjct: 264 VYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPC 323
Query: 288 VGTCPKTCRAE------KPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGER 341
G CPK C + + S NID F +CT I G+++ L TG +N D +
Sbjct: 324 GGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGNLDFL---ITG---LNGDP--WHK 375
Query: 342 YPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVK 401
P ++P+ L VF TVRE+TGYLN+Q+ P+ + S F NL IGGR + F+ L +
Sbjct: 376 IPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKN 435
Query: 402 TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQ-CEK 460
+++G I I NR LCY + W K+++ +++ K+ PR+ C
Sbjct: 436 LNVTSLGFRSLKEISAGRIYISANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVA 495
Query: 461 NNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSE 518
VCDP CS+ GCWGPGP QCLSC+NY+ G +C+ +C+ G + A C CH E
Sbjct: 496 EGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPE 555
Query: 519 C--LDG---CTGASRANCTSCKHVRDGPYCVAQCP 548
C + G C G+ C C H RDGP+CV+ CP
Sbjct: 556 CQPMGGTATCNGSGSDTCAQCAHFRDGPHCVSSCP 590
Score = 346 bits (851), Expect = 3e-94
Identities = 206/583 (35%), Positives = 307/583 (52%), Gaps = 48/583 (8%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC-----PSDHFTDEIGRNCTPCHSECK 686
C PLC +G C C + RG C C F E C CH EC+
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEA--ECFSCHPECQ 557
Query: 687 G------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNI---PNKIYFDEQ 737
C G G C +C + + + P +C +CP + IY
Sbjct: 558 PMGGTATCNGSGSDTCAQCAHFR-----------DGP-HCVSSCPHGVLGAKGPIYKYPD 605
Query: 738 LQDPIEEPY--CSEHANDIPTATARTSTVLVI--------ILVIASLFLAVLAIIGYNFR 787
+Q+ + C++ T+++I + VIA L + + + G
Sbjct: 606 VQNECRPCHENCTQGCKGPELQDCLGQTLVLIGKTHLTMALTVIAGLVVIFMMLGGTFLY 665
Query: 788 QKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVY 847
+ + + M L E EPL P+ K N RI KE ELR+ +LG G FG V+
Sbjct: 666 WRGRRIQNKRAMRRYLERGESIEPLDPSE-KANKVLARIFKETELRKLKVLGSGVFGTVH 724
Query: 848 KGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMM 907
KGVW+PEGE++KIPV IKV+++ +G + + + + S++H ++++LL +C + +
Sbjct: 725 KGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVTDHMLAIGSLDHAHIVRLLGLCPGSSLQ 784
Query: 908 LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQT 967
L+TQ +PLG L+D+VR H+ +G + LNW QIA+GM YLEE +VHR+LAARNVL+++
Sbjct: 785 LVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVLLKS 844
Query: 968 PNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEI 1027
P+ V++ DFG+A LL ++ + + K PIKW+ALE I +TH+SDVW++GVT+WE+
Sbjct: 845 PSQVQVADFGVADLLPPDDKQLLYSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTVWEL 904
Query: 1028 LSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADT 1087
+++GA PY + VP+L+E G +L QP ICT+D+Y VMV CWM+D + RPTFK+LA+
Sbjct: 905 MTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKELANE 964
Query: 1088 FAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPKFKS 1147
F MARDP RYLVI + P + E + N E +D D L+ + +
Sbjct: 965 FTRMARDPPRYLVIKRESG---PGIAPGPEPHGLTNKKLEEVELEPELDLDLDLEAEEDN 1021
Query: 1148 MTGTVTTNSALSAGMET-----QTSSLKPCTSSSWPNNAGQDG 1185
+ T T SALS + T + SL +S P N G G
Sbjct: 1022 L-ATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLG 1063
Score = 99 bits (238), Expect = 6e-20
Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXX 409
L +REVTGY+ V + F++L NL V+ G QV + FA ++
Sbjct: 74 LSFLQWIREVTGYVLVAMNE--FSTLP-LPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHA 130
Query: 410 ------XXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
+ SG + I +N LC+ D I W +V+ +D + +++ NG R C +
Sbjct: 131 LRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG--RSCPPCHE 188
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
VC +C WGPG + C + IC C+ H + + C CH EC GC
Sbjct: 189 VCKGRC-----WGPGSEDCQTLTK----TICAPQCNGH--CFGPNPNQC--CHDECAGGC 235
Query: 524 TGASRANCTSCKHVRDGPYCVAQCPE 549
+G +C +C+H D CV +CP+
Sbjct: 236 SGPQDTDCFACRHFNDSGACVPRCPQ 261
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 13/93 (13%)
Query: 452 NGDPRQC--EKNNLVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNC-----SV 500
NG+PR+ E C P+C G C G G D C C ++ G C+ +C
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMGGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 501 HPGLYKAD--HKSCKQCHSECLDGCTGASRANC 531
+YK C+ CH C GC G +C
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDC 629
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 25/125 (20%)
Query: 195 CNTFCA-GGCTGPLPTQCLACRNFYDEGTCSQEC------PSMQIYNPTTYSWEPN--PN 245
C+ C+ GGC GP P QCL+CRN+ G C C P + +S P P
Sbjct: 500 CDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPM 559
Query: 246 GKYAY----GATCVRNCPEHLLKDNGACVRSCPPNKTAVNG----------ECIPCVGTC 291
G A G+ C +D CV SCP G EC PC C
Sbjct: 560 GGTATCNGSGSDTCAQCAH--FRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENC 617
Query: 292 PKTCR 296
+ C+
Sbjct: 618 TQGCK 622
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/94 (29%), Positives = 36/94 (38%), Gaps = 13/94 (13%)
Query: 617 NVKPLEGKVKIACRKCHPLCIKCVGF----GIHEQVCQVCNGFKRGDQCEDECPSD---- 668
N +P E + C CHP C G G C C F+ G C CP
Sbjct: 537 NGEPREFAHEAECFSCHPECQPMGGTATCNGSGSDTCAQCAHFRDGPHCVSSCPHGVLGA 596
Query: 669 ----HFTDEIGRNCTPCHSEC-KGCTGPGPTDCI 697
+ ++ C PCH C +GC GP DC+
Sbjct: 597 KGPIYKYPDVQNECRPCHENCTQGCKGPELQDCL 630
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 628 ACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK 686
+C CH +C +C G G + CQ QC C + C CH EC
Sbjct: 182 SCPPCHEVCKGRCWGPGSED--CQTLTKTICAPQCNGHCFGPN-----PNQC--CHDECA 232
Query: 687 G-CTGPGPTDCIKCKN 701
G C+GP TDC C++
Sbjct: 233 GGCSGPQDTDCFACRH 248
Score = 40.3 bits (90), Expect = 0.048
Identities = 15/23 (65%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 675 GRNCTPCHSECKG-CTGPGPTDC 696
GR+C PCH CKG C GPG DC
Sbjct: 180 GRSCPPCHEVCKGRCWGPGSEDC 202
Score = 33.1 bits (72), Expect = 7.2
Identities = 13/27 (48%), Positives = 16/27 (59%), Gaps = 1/27 (3%)
Query: 675 GRNCTPCHSECKGCTGPGPTDCIKCKN 701
G+ C P S GC GPGP C+ C+N
Sbjct: 497 GKVCDPLCSS-GGCWGPGPGQCLSCRN 522
>AY698023-1|AAT97978.1| 645|Homo sapiens epidermal growth factor
receptor protein.
Length = 645
Score = 398 bits (979), Expect = e-110
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPKDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 67.3 bits (157), Expect = 4e-10
Identities = 77/294 (26%), Positives = 122/294 (41%), Gaps = 48/294 (16%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W + +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPKDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPN 276
C + CP+ + T W+ G + C NC G + CP N
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCPTN 639
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 636
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPKDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPKDCVSCRNV 529
>K03193-1|AAA52371.1| 657|Homo sapiens EGFR protein.
Length = 657
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 66.9 bits (156), Expect = 5e-10
Identities = 77/294 (26%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPN 276
C + CP+ + T W+ G + C NC G + CP N
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCPTN 639
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 21/115 (18%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANCTSCKHVRDGPYCVAQCPESRY 552
+ ++K A H C CH C GCTG C + +G Y V+ P S Y
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGCPT-----NGSYIVSHFPRSFY 652
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNV 529
>AF288738-4|AAG35790.1| 628|Homo sapiens truncated epidermal growth
factor receptor protein.
Length = 628
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 474 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 512
Query: 184 GRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 513 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 572
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 573 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 607
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNV 529
>AF288738-3|AAG35786.1| 705|Homo sapiens p110 epidermal growth
factor receptor protein.
Length = 705
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 474 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 512
Query: 184 GRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 513 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 572
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 573 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 607
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNV 529
>AF288738-2|AAG35788.1| 657|Homo sapiens A431-specific p115
epidermal growth factor receptor protein.
Length = 657
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 66.9 bits (156), Expect = 5e-10
Identities = 77/294 (26%), Positives = 121/294 (41%), Gaps = 48/294 (16%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 474 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 531
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 532 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 590
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPN 276
C + CP+ + T W+ G + C NC G + CP N
Sbjct: 591 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCPTN 639
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/115 (31%), Positives = 51/115 (44%), Gaps = 21/115 (18%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 544 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 603
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANCTSCKHVRDGPYCVAQCPESRY 552
+ ++K A H C CH C GCTG C + +G Y V+ P S Y
Sbjct: 604 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGCPT-----NGSYIVSHFPRSFY 652
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 545 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 602
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 603 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNV 529
>AF125253-1|AAG43240.1| 705|Homo sapiens truncated epidermal growth
factor receptor precursor protein.
Length = 705
Score = 397 bits (978), Expect = e-109
Identities = 221/567 (38%), Positives = 307/567 (54%), Gaps = 41/567 (7%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXX 408
L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 391 ELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLG 449
Query: 409 XXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQ 468
++ G + I N+NLCYA+ I W KL + K I N C+ VC
Sbjct: 450 LRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHAL 509
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD----- 521
CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 510 CSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNI 569
Query: 522 GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 570 TCTGRGPDNCIQCAHYIDGPHCVKTCP 596
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 359 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 418
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 419 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 473
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 474 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 512
Query: 184 GRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 513 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 572
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 573 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 607
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 496 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 555
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 556 IQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNV 529
>X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA fragment
for epidermal growth factor (EGF) receptor. ).
Length = 800
Score = 390 bits (959), Expect = e-107
Identities = 206/461 (44%), Positives = 279/461 (60%), Gaps = 34/461 (7%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPS-DHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 354 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 413
Query: 679 TPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKI 732
CH EC CTG GP +CI+C + ++ G +C TCP + +
Sbjct: 414 IQCHPECLPQAMNITCTGRGPDNCIQCAH---YIDGP---------HCVKTCPAGVMGEN 461
Query: 733 ------YFDEQLQDPIEEPYCSEHAND-----IPTATARTSTVLVIILVIASLFLAVLAI 781
Y D + P C+ PT + ++ ++ L L V
Sbjct: 462 NTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALG 521
Query: 782 IGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFG 841
IG R++ +K ++ +L E EPL P+ PN A LRI+KE E ++ +LG G
Sbjct: 522 IGLFMRRRHIVRKRTLRR--LLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSG 579
Query: 842 AFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVC 901
AFG VYKG+W+PEGE VKIPVAIK L+E T +KE L+EAY+MASV++P++ +LL +C
Sbjct: 580 AFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC 639
Query: 902 MTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAAR 961
+T+ + LITQLMP GCL+DYVR HK+ IGS+ LNWC QIA+GM YLE++RLVHRDLAAR
Sbjct: 640 LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAAR 699
Query: 962 NVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFG 1021
NVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+ALE I HRI+TH+SDVW++G
Sbjct: 700 NVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYG 759
Query: 1022 VTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
VT+WE++++G++PY+ I A + ++E G +LPQP ICT+D
Sbjct: 760 VTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTID 800
Score = 341 bits (839), Expect = 8e-93
Identities = 182/467 (38%), Positives = 250/467 (53%), Gaps = 37/467 (7%)
Query: 106 VLQGSVGIYSNFNLCHVKTINW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWA 161
+L G+V +N LC+V++I W D ++ D L+ ++ F LG + P + W
Sbjct: 1 ILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWG 59
Query: 162 AGESIENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEG 221
AGE ENCQK +K IC+ QC+ GRC G +P DCC+ CA GCTGP + CL CR F DE
Sbjct: 60 AGE--ENCQKLTKIICAQQCS-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEA 116
Query: 222 TCSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAV 280
TC CP + +YNPTTY + NP GKY++GATCV+ CP +++ D+G+CVR+C + +
Sbjct: 117 TCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEM 176
Query: 281 NGE----CIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTG 328
+ C C G C K C + I++ NI FK+CT I G + IL + F G
Sbjct: 177 EEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG 236
Query: 329 FQQVNQDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQ 388
SF P ++P L++ TV+E+TG+L +QA N T L F NLE+I GR
Sbjct: 237 -------DSF-THTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRT 288
Query: 389 VVENLFASLYIVKTXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQI 448
F SL +V ++ G + I N+NLCYA+ I W KL + K
Sbjct: 289 KQHGQF-SLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTK 347
Query: 449 IQKNGDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK-- 506
I N C+ VC CS +GCWGP P C+SC+N + G C+D C++ G +
Sbjct: 348 IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREF 407
Query: 507 ADHKSCKQCHSECLD-----GCTGASRANCTSCKHVRDGPYCVAQCP 548
++ C QCH ECL CTG NC C H DGP+CV CP
Sbjct: 408 VENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP 454
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 217 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 276
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 277 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 331
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 332 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 370
Query: 184 GRCFGPNPRDC--CNTFCAG-GCTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 371 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 430
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 431 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 465
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 402 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 461
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 462 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 494
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 44 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 96
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 97 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 123
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 403 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 460
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 461 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 494
>M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein protein.
Length = 295
Score = 371 bits (913), Expect = e-102
Identities = 162/296 (54%), Positives = 226/296 (76%), Gaps = 5/296 (1%)
Query: 849 GVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMML 908
G+W+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +LL +C+T+ + L
Sbjct: 1 GIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQL 60
Query: 909 ITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTP 968
+TQLMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRDLAARNVLV++P
Sbjct: 61 VTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSP 120
Query: 969 NSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEIL 1028
N VKITDFGLA+LLDI+E EY A GGK+PIKW+ALE I R FTH+SDVW++GVT+WE++
Sbjct: 121 NHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELM 180
Query: 1029 SYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTF 1088
++GA+PY+ I AR +P+L+E G +LPQP ICT+D+Y +MV CWM+D++ RP F++L F
Sbjct: 181 TFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF 240
Query: 1089 AEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRNLSSAMEGPESLVDADEYLQPK 1144
+ MARDP R++VI + + + ++ + + LVDA+EYL P+
Sbjct: 241 SRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLED-----DDMGDLVDAEEYLVPQ 291
>AC105921-1|AAY24303.1| 552|Homo sapiens unknown protein.
Length = 552
Score = 352 bits (866), Expect = 4e-96
Identities = 180/465 (38%), Positives = 252/465 (54%), Gaps = 32/465 (6%)
Query: 106 VLQGSVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGES 165
+L G V + N LC+ TI+W +I ++ T + G R G +
Sbjct: 1 ILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPT 60
Query: 166 IENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQ 225
+CQ ++T+C+ QC GRC+GP DCC+ CAGGC+GP T C AC NF D G C
Sbjct: 61 ENHCQTLTRTVCAEQC-DGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVT 119
Query: 226 ECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG- 282
+CP +YNPTT+ E N N KY YGA CV+ CP + + D+ +CVR+CP +K V NG
Sbjct: 120 QCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGI 179
Query: 283 -ECIPCVGTCPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVN 333
C PC CPK C + + + S NID F +CT I+G++ L TG
Sbjct: 180 KMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFL---VTGIH--G 234
Query: 334 QDYSFGERYPKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENL 393
Y+ E ++P+ L VF TVRE+TG+LN+Q+ PN T S F NL IGGR + L
Sbjct: 235 DPYNAIE---AIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGL 291
Query: 394 FASLYIVK-TXXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKN 452
SL I+K +++G I I +N NLCY I W L + + + +I+ N
Sbjct: 292 --SLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDN 349
Query: 453 GDPRQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHK 510
C +VC+ CS+DGCWGPGPDQCLSC+ ++ G ICI++C+++ G ++ +
Sbjct: 350 RKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGS 409
Query: 511 SCKQCHSEC---LDG---CTGASRANCTSCKHVRDGPYCVAQCPE 549
C +C +C DG C G NCT C H +DGP CV +CP+
Sbjct: 410 ICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPD 454
Score = 74.5 bits (175), Expect = 2e-12
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 16/136 (11%)
Query: 417 SGAIAIMENRNLCYADKIAWNKLVKSK--DHKQIIQKNGDPRQCEKNNLVCDPQCSADGC 474
+G + + +N+ LCYAD I W +V++ + ++ NG C + C C+ C
Sbjct: 3 NGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSG-CGR----CHKSCTGR-C 56
Query: 475 WGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGCTGASRANCTSC 534
WGP + C + E C C G Y +D C CH EC GC+G +C +C
Sbjct: 57 WGPTENHCQTLTRTVCAEQCDGRCY---GPYVSD---C--CHRECAGGCSGPKDTDCFAC 108
Query: 535 KHVRDGPYCVAQCPES 550
+ D CV QCP++
Sbjct: 109 MNFNDSGACVTQCPQT 124
Score = 71.7 bits (168), Expect = 2e-11
Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 56/304 (18%)
Query: 16 DRFTNCTYVDGNLE--LTWLEN------ESMD---LSFLKYIREVTGYVLISHVKVHKI- 63
D+F NCT ++GNL +T + E++D L+ + +RE+TG++ I +
Sbjct: 213 DKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTD 272
Query: 64 --VLPQLQIIRGRTLFKLNVREEEFALLVTMSTAFT-LELPALRDVLQGSVGIYSNFNLC 120
V L I GR L+ +LL+ T L+ +L+++ G++ I N NLC
Sbjct: 273 FSVFSNLVTIGGRVLYS------GLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLC 326
Query: 121 HVKTINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQ 180
+ TINW + F+ I N R+V + R A ENC +C+
Sbjct: 327 YYHTINWTTL--------FSTI-------NQRIVIRDNRKA-----ENCTA-EGMVCNHL 365
Query: 181 CAQGRCFGPNPRDC--CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQ---ECPSMQIYN 234
C+ C+GP P C C F G C R F + C + +C M+
Sbjct: 366 CSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGL 425
Query: 235 PTTYSWEPNPNGKYAY---GATCVRNCPEHLLKDNGACVRSCPPNKTAVNGECIPCVGTC 291
T + P+ K ++ G CV CP+ L N + P++ EC PC C
Sbjct: 426 LTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDR-----ECHPCHPNC 480
Query: 292 PKTC 295
+ C
Sbjct: 481 TQGC 484
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 14/94 (14%)
Query: 452 NGDPRQCEKNNLV--CDPQCSA--DG---CWGPGPDQCLSCQNYNFGEICIDNC-----S 499
+G+ R+ E ++ CDPQC DG C GPGPD C C ++ G C++ C
Sbjct: 399 DGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQG 458
Query: 500 VHPGLYK-AD-HKSCKQCHSECLDGCTGASRANC 531
+ ++K AD + C CH C GC G + +C
Sbjct: 459 ANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 492
Score = 52.8 bits (121), Expect = 8e-06
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 612 NEWVGNVKPLEGKVKIACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHF 670
N W N+ + C +CH C +C +G E CQ +QC+ C +
Sbjct: 28 NPWPSNLTLVSTNGSSGCGRCHKSCTGRC--WGPTENHCQTLTRTVCAEQCDGRCYGPYV 85
Query: 671 TDEIGRNCTPCHSECKG-CTGPGPTDCIKCKN 701
+D C CH EC G C+GP TDC C N
Sbjct: 86 SD-----C--CHRECAGGCSGPKDTDCFACMN 110
Score = 50.8 bits (116), Expect = 3e-05
Identities = 56/199 (28%), Positives = 77/199 (38%), Gaps = 46/199 (23%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP--SDHFTD-EIGRNCTPCHSECKG- 687
C+ LC +G C C F RG C + C F + E G C C +C+
Sbjct: 362 CNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKM 421
Query: 688 ------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIPNKIYFDEQLQDP 741
C GPGP +C KC + K + P NC + CPD + F + DP
Sbjct: 422 EDGLLTCHGPGPDNCTKCSHFK-----------DGP-NCVEKCPDGLQGANSFIFKYADP 469
Query: 742 IEE-----PYCSEHAND--------IP-----TATARTSTVLVIILVIASLFLAVLAIIG 783
E P C++ N P T T L+ VI LF +L I+G
Sbjct: 470 DRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLF--ILVIVG 527
Query: 784 YNF----RQKAKAKKEAVK 798
F R+K+ KK A++
Sbjct: 528 LTFAVYVRRKSIKKKRALR 546
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 629 CRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-----SDHFTDEIG---RNCTP 680
C K + C G G C C+ FK G C ++CP ++ F + R C P
Sbjct: 418 CEKMEDGLLTCHGPGPDN--CTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHP 475
Query: 681 CHSEC-KGCTGPGPTDCI 697
CH C +GC GP DCI
Sbjct: 476 CHPNCTQGCNGPTSHDCI 493
>BC118665-1|AAI18666.1| 464|Homo sapiens EGFR protein protein.
Length = 464
Score = 313 bits (769), Expect = 3e-84
Identities = 156/393 (39%), Positives = 210/393 (53%), Gaps = 30/393 (7%)
Query: 176 ICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNP 235
IC+ QC+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNP
Sbjct: 8 ICAQQCS-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNP 66
Query: 236 TTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGT 290
TTY + NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G
Sbjct: 67 TTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGP 126
Query: 291 CPKTC--------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERY 342
C K C + I++ NI FK+CT I G + IL + F G SF
Sbjct: 127 CRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THT 178
Query: 343 PKMEPDALEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKT 402
P ++P L++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 179 PPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSL 237
Query: 403 XXXXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNN 462
++ G + I N+NLCYA+ I W KL + K I N C+
Sbjct: 238 NITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATG 297
Query: 463 LVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECL 520
VC CS +GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL
Sbjct: 298 QVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECL 357
Query: 521 D-----GCTGASRANCTSCKHVRDGPYCVAQCP 548
CTG NC C H DGP+CV CP
Sbjct: 358 PQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCP 390
Score = 71.3 bits (167), Expect = 2e-11
Identities = 74/275 (26%), Positives = 113/275 (41%), Gaps = 48/275 (17%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 153 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 212
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 213 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 267
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPARWAAGESIENCQKFSKTICSPQCAQ 183
TINW ++ Q T ++++ EN K + +C C+
Sbjct: 268 TINWKKLFGTSGQKT-------------KIISNRG--------ENSCKATGQVCHALCSP 306
Query: 184 GRCFGPNPRDC--CNTFCAG-GCTGPLPTQCLACRNFYDEGTCSQECPSM--QIYNPTTY 238
C+GP PRDC C G C R F + C Q P Q N T
Sbjct: 307 EGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCT 366
Query: 239 SWEPN---PNGKYAYGATCVRNCPEHLLKDNGACV 270
P+ Y G CV+ CP ++ +N V
Sbjct: 367 GRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLV 401
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 338 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 397
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 398 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 430
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 290 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 349
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 350 IQCHPECLPQAMNITCTGRGPDNCIQC 376
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 339 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 396
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 397 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 430
Score = 35.5 bits (78), Expect = 1.4
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 13/46 (28%)
Query: 681 CHSECK-GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
CH++C GCTGP +DC+ C+ + DE C DTCP
Sbjct: 26 CHNQCAAGCTGPRESDCLVCRKFR---------DE---ATCKDTCP 59
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 300 CHALCSPEGCWGPEPRDCVSCRNV 323
>AK131568-1|BAD18701.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ16821 fis, clone TRACH3021066, highly similar
to Receptor protein-tyrosine kinase ERBB-2 precursor (EC
2.7.1.112). ).
Length = 435
Score = 281 bits (689), Expect = 1e-74
Identities = 149/339 (43%), Positives = 204/339 (60%), Gaps = 30/339 (8%)
Query: 676 RNCTPCHSECKG------CTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCPDNIP 729
R+C PCH EC+ C GP C+ C + K + PF C CP +
Sbjct: 108 RHCLPCHPECQPQNGSVTCFGPEADQCVACAHYK-----------DPPF-CVARCPSGVK 155
Query: 730 NKIYFDEQLQDPIEEPYCSE------HA------NDIPTATARTSTVLVIILVIASLFLA 777
+ + + P EE C H+ P ++ V+ L +
Sbjct: 156 PDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRANPLTSIVSAVVGILLVV 215
Query: 778 VLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRPTNVKPNLAKLRIVKEAELRRGGM 837
VL ++ ++ + K M +L E EPL P+ PN A++RI+KE ELR+ +
Sbjct: 216 VLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKV 275
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG GAFG VYKG+W+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +L
Sbjct: 276 LGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL 335
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRD 957
L +C+T+ + L+TQLMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRD
Sbjct: 336 LGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRD 395
Query: 958 LAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKM 996
LAARNVLV++PN VKITDFGLA+LLDI+E EY A GGK+
Sbjct: 396 LAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKV 434
Score = 50.4 bits (115), Expect = 4e-05
Identities = 17/41 (41%), Positives = 24/41 (58%)
Query: 463 LVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPG 503
L C C+ CWGPGP QC++C + G+ C++ C V G
Sbjct: 32 LACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQG 72
Score = 44.4 bits (100), Expect = 0.003
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 9/85 (10%)
Query: 456 RQCEKNNLVCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNC--SVHPGL-------YK 506
R C + C PQ + C+GP DQC++C +Y C+ C V P L +
Sbjct: 108 RHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFP 167
Query: 507 ADHKSCKQCHSECLDGCTGASRANC 531
+ +C+ C C C C
Sbjct: 168 DEEGACQPCPINCTHSCVDLDDKGC 192
Score = 43.6 bits (98), Expect = 0.005
Identities = 31/104 (29%), Positives = 38/104 (36%), Gaps = 2/104 (1%)
Query: 195 CNTFCAGG-CTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWEPNPNGKYAYGAT 253
C+ CA G C GP PTQC+ C F C +EC +Q Y W G + T
Sbjct: 34 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGYEGRRRGWLEGCMGLLSDPLT 93
Query: 254 CVRNCPEHLLKDNGACVRSCPPNKTAVNGECIPCVGTCPKTCRA 297
V + N C P NG + C G C A
Sbjct: 94 TVPSLRLPREYVNARHCLPCHPECQPQNGS-VTCFGPEADQCVA 136
Score = 33.9 bits (74), Expect = 4.1
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 5/36 (13%)
Query: 681 CHSEC-KG-CTGPGPTDCIKCKNLKIFLGGSDASDE 714
CH C +G C GPGPT C+ C FL G + +E
Sbjct: 34 CHQLCARGHCWGPGPTQCVNCSQ---FLRGQECVEE 66
Score = 32.7 bits (71), Expect = 9.6
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 632 CHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDEC 665
CH LC + +G C C+ F RG +C +EC
Sbjct: 34 CHQLCARGHCWGPGPTQCVNCSQFLRGQECVEEC 67
Score = 32.7 bits (71), Expect = 9.6
Identities = 12/27 (44%), Positives = 15/27 (55%)
Query: 203 CTGPLPTQCLACRNFYDEGTCSQECPS 229
C GP QC+AC ++ D C CPS
Sbjct: 126 CFGPEADQCVACAHYKDPPFCVARCPS 152
>AC012069-1|AAY15092.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 277 bits (680), Expect = 2e-73
Identities = 127/214 (59%), Positives = 166/214 (77%), Gaps = 4/214 (1%)
Query: 944 GMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLAL 1003
GM YLEE+RLVHRDLAARNVLV++PN VKITDFGLA+LL+ +E EY A GGKMPIKW+AL
Sbjct: 1 GMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMAL 60
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
ECI +R FTH+SDVW++GVTIWE++++G +PY+ I R +P+L+E G +LPQP ICT+D+
Sbjct: 61 ECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDV 120
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRN 1123
Y VMV CWM+DADSRP FK+LA F+ MARDP RYLVI GD M+LPS ++ + +N
Sbjct: 121 YMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPS---PNDSKFFQN 177
Query: 1124 LSSAMEGPESLVDADEYLQPKFKSMTGTVTTNSA 1157
L E E ++DA+EYL P+ ++ + T+ A
Sbjct: 178 LLDE-EDLEDMMDAEEYLVPQAFNIPPPIYTSRA 210
>AC073324-1|AAS07524.1| 387|Homo sapiens unknown protein.
Length = 387
Score = 264 bits (646), Expect = 2e-69
Identities = 124/230 (53%), Positives = 164/230 (71%), Gaps = 5/230 (2%)
Query: 944 GMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLAL 1003
GM YLE++RLVHRDLAARNVLV+TP VKITDFGLAKLL E EY A GGK+PIKW+AL
Sbjct: 1 GMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMAL 60
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E I HRI+TH+SDVW++GVT+WE++++G++PY+ I A + ++E G +LPQP ICT+D+
Sbjct: 61 ESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDV 120
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVIPGDKFMRLPSYSTQDEKEMIRN 1123
Y +MV CWM+DADSRP F++L F++MARDP RYLVI GD+ M LPS + R
Sbjct: 121 YMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPS---PTDSNFYRA 177
Query: 1124 LSSAMEGPESLVDADEYLQPKFKSMTGTVTTNSALSAGME-TQTSSLKPC 1172
L E + +VDADEYL P+ + T+ + L + + T +S C
Sbjct: 178 LMDE-EDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVAC 226
>U95089-1|AAB53063.1| 405|Homo sapiens truncated epidermal growth
factor receptor-like protein precursor protein.
Length = 405
Score = 256 bits (627), Expect = 4e-67
Identities = 148/373 (39%), Positives = 212/373 (56%), Gaps = 33/373 (8%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTG 361
L++ TV+E+TG
Sbjct: 391 ELDILKTVKEITG 403
Score = 79.4 bits (187), Expect = 8e-14
Identities = 56/205 (27%), Positives = 78/205 (38%), Gaps = 21/205 (10%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIV-----KTXX 404
L T++EV GY+ + N NL++I G EN +A + KT
Sbjct: 76 LSFLKTIQEVAGYVLIAL---NTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGL 132
Query: 405 XXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQI-IQKNGDPRQCEKNNL 463
+ GA+ N LC + I W +V S + + C+K
Sbjct: 133 KELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQK--- 189
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
CDP C CWG G + C IC CS G + S CH++C GC
Sbjct: 190 -CDPSCPNGSCWGAGEENCQKLTKI----ICAQQCS---GRCRGKSPS-DCCHNQCAAGC 240
Query: 524 TGASRANCTSCKHVRDGPYCVAQCP 548
TG ++C C+ RD C CP
Sbjct: 241 TGPRESDCLVCRKFRDEATCKDTCP 265
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
>U48722-1|AAC50802.1| 405|Homo sapiens epidermal growth factor
receptor precursor protein.
Length = 405
Score = 256 bits (627), Expect = 4e-67
Identities = 148/373 (39%), Positives = 212/373 (56%), Gaps = 33/373 (8%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTG 361
L++ TV+E+TG
Sbjct: 391 ELDILKTVKEITG 403
Score = 79.4 bits (187), Expect = 8e-14
Identities = 56/205 (27%), Positives = 78/205 (38%), Gaps = 21/205 (10%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIV-----KTXX 404
L T++EV GY+ + N NL++I G EN +A + KT
Sbjct: 76 LSFLKTIQEVAGYVLIAL---NTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGL 132
Query: 405 XXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQI-IQKNGDPRQCEKNNL 463
+ GA+ N LC + I W +V S + + C+K
Sbjct: 133 KELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQK--- 189
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
CDP C CWG G + C IC CS G + S CH++C GC
Sbjct: 190 -CDPSCPNGSCWGAGEENCQKLTKI----ICAQQCS---GRCRGKSPS-DCCHNQCAAGC 240
Query: 524 TGASRANCTSCKHVRDGPYCVAQCP 548
TG ++C C+ RD C CP
Sbjct: 241 TGPRESDCLVCRKFRDEATCKDTCP 265
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
>AY698024-1|AAT97979.1| 405|Homo sapiens epidermal growth factor
receptor short isoform protein.
Length = 405
Score = 256 bits (627), Expect = 4e-67
Identities = 148/373 (39%), Positives = 212/373 (56%), Gaps = 33/373 (8%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTG 361
L++ TV+E+TG
Sbjct: 391 ELDILKTVKEITG 403
Score = 79.4 bits (187), Expect = 8e-14
Identities = 56/205 (27%), Positives = 78/205 (38%), Gaps = 21/205 (10%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIV-----KTXX 404
L T++EV GY+ + N NL++I G EN +A + KT
Sbjct: 76 LSFLKTIQEVAGYVLIAL---NTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGL 132
Query: 405 XXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQI-IQKNGDPRQCEKNNL 463
+ GA+ N LC + I W +V S + + C+K
Sbjct: 133 KELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQK--- 189
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
CDP C CWG G + C IC CS G + S CH++C GC
Sbjct: 190 -CDPSCPNGSCWGAGEENCQKLTKI----ICAQQCS---GRCRGKSPS-DCCHNQCAAGC 240
Query: 524 TGASRANCTSCKHVRDGPYCVAQCP 548
TG ++C C+ RD C CP
Sbjct: 241 TGPRESDCLVCRKFRDEATCKDTCP 265
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
>AF288738-5|AAG35787.1| 405|Homo sapiens p60 epidermal growth
factor receptor protein.
Length = 405
Score = 256 bits (627), Expect = 4e-67
Identities = 148/373 (39%), Positives = 212/373 (56%), Gaps = 33/373 (8%)
Query: 8 DTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKVHKIVLPQ 67
+ H+ +L+ F NC V GNLE+T+++ + DLSFLK I+EV GYVLI+ V +I L
Sbjct: 45 EDHFLSLQRMFNNCEVVLGNLEITYVQR-NYDLSFLKTIQEVAGYVLIALNTVERIPLEN 103
Query: 68 LQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPA--LRDVLQGSVGIYSNFNLCHVKTI 125
LQIIRG ++ + + T ELP L+++L G+V +N LC+V++I
Sbjct: 104 LQIIRGNMYYENSYALAVLSNYDANKTGLK-ELPMRNLQEILHGAVRFSNNPALCNVESI 162
Query: 126 NW-DEINQD-LTQVTFTFIILPLGKGNARVVTQP--ARWAAGESIENCQKFSKTICSPQC 181
W D ++ D L+ ++ F LG + P + W AGE ENCQK +K IC+ QC
Sbjct: 163 QWRDIVSSDFLSNMSMDFQN-HLGSCQKCDPSCPNGSCWGAGE--ENCQKLTKIICAQQC 219
Query: 182 AQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQIYNPTTYSWE 241
+ GRC G +P DCC+ CA GCTGP + CL CR F DE TC CP + +YNPTTY +
Sbjct: 220 S-GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMD 278
Query: 242 PNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTC- 295
NP GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 279 VNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCN 338
Query: 296 -------RAEKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPD 348
+ I++ NI FK+CT I G + IL + F G SF P ++P
Sbjct: 339 GIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRG-------DSF-THTPPLDPQ 390
Query: 349 ALEVFSTVREVTG 361
L++ TV+E+TG
Sbjct: 391 ELDILKTVKEITG 403
Score = 79.4 bits (187), Expect = 8e-14
Identities = 56/205 (27%), Positives = 78/205 (38%), Gaps = 21/205 (10%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIV-----KTXX 404
L T++EV GY+ + N NL++I G EN +A + KT
Sbjct: 76 LSFLKTIQEVAGYVLIAL---NTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGL 132
Query: 405 XXXXXXXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQI-IQKNGDPRQCEKNNL 463
+ GA+ N LC + I W +V S + + C+K
Sbjct: 133 KELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQK--- 189
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
CDP C CWG G + C IC CS G + S CH++C GC
Sbjct: 190 -CDPSCPNGSCWGAGEENCQKLTKI----ICAQQCS---GRCRGKSPS-DCCHNQCAAGC 240
Query: 524 TGASRANCTSCKHVRDGPYCVAQCP 548
TG ++C C+ RD C CP
Sbjct: 241 TGPRESDCLVCRKFRDEATCKDTCP 265
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/99 (32%), Positives = 43/99 (43%), Gaps = 20/99 (20%)
Query: 628 ACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSEC-K 686
+C+KC P C +G E+ CQ QC C +D C CH++C
Sbjct: 186 SCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSD-----C--CHNQCAA 238
Query: 687 GCTGPGPTDCIKCKNLKIFLGGSDASDENAPFNCTDTCP 725
GCTGP +DC+ C+ + DE C DTCP
Sbjct: 239 GCTGPRESDCLVCRKFR---------DE---ATCKDTCP 265
>M12036-1|AAA35978.1| 171|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) gene, partial cds. ).
Length = 171
Score = 246 bits (603), Expect = 3e-64
Identities = 110/171 (64%), Positives = 142/171 (83%)
Query: 852 VPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQ 911
+P+GENVKIPVAIKVL+E T +KE L+EAY+MA V P + +LL +C+T+ + L+TQ
Sbjct: 1 IPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQ 60
Query: 912 LMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSV 971
LMP GCL+D+VR ++ ++GS+ LNWC QIA+GM+YLE+ RLVHRDLAARNVLV++PN V
Sbjct: 61 LMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHV 120
Query: 972 KITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGV 1022
KITDFGLA+LLDI+E EY A GGK+PIKW+ALE I R FTH+SDVW++GV
Sbjct: 121 KITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGV 171
>BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 331
Score = 237 bits (579), Expect = 3e-61
Identities = 123/306 (40%), Positives = 171/306 (55%), Gaps = 25/306 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+SV + + Y+ L + C V GNLE+ L + DLSFL++IREVTGYVL++ +
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMS-------TAFTLELPALRDVLQGSVGI 113
+ LP L+++RG ++ + +FA+ V ++ L L L ++L G V I
Sbjct: 95 STLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYI 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPARWAAGESIENCQK 171
N LCH+ TI+W +I +D ++ G+ V + W G E+CQ
Sbjct: 150 EKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKGRCWGPGS--EDCQT 204
Query: 172 FSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQ 231
+KTIC+PQC G CFGPNP CC+ CAGGC+GP T C ACR+F D G C CP
Sbjct: 205 LTKTICAPQC-NGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPL 263
Query: 232 IYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPC 287
+YN T+ EPNP+ KY YG CV +CP + + D +CVR+CPP+K V NG C PC
Sbjct: 264 VYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPC 323
Query: 288 VGTCPK 293
G CPK
Sbjct: 324 GGLCPK 329
Score = 99 bits (238), Expect = 6e-20
Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXX 409
L +REVTGY+ V + F++L NL V+ G QV + FA ++
Sbjct: 74 LSFLQWIREVTGYVLVAMNE--FSTLP-LPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHA 130
Query: 410 ------XXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
+ SG + I +N LC+ D I W +V+ +D + +++ NG R C +
Sbjct: 131 LRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG--RSCPPCHE 188
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
VC +C WGPG + C + IC C+ H + + C CH EC GC
Sbjct: 189 VCKGRC-----WGPGSEDCQTLTK----TICAPQCNGH--CFGPNPNQC--CHDECAGGC 235
Query: 524 TGASRANCTSCKHVRDGPYCVAQCPE 549
+G +C +C+H D CV +CP+
Sbjct: 236 SGPQDTDCFACRHFNDSGACVPRCPQ 261
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 628 ACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK 686
+C CH +C +C G G + CQ QC C + C CH EC
Sbjct: 182 SCPPCHEVCKGRCWGPGSED--CQTLTKTICAPQCNGHCFGPN-----PNQC--CHDECA 232
Query: 687 G-CTGPGPTDCIKCKN 701
G C+GP TDC C++
Sbjct: 233 GGCSGPQDTDCFACRH 248
Score = 40.3 bits (90), Expect = 0.048
Identities = 15/23 (65%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 675 GRNCTPCHSECKG-CTGPGPTDC 696
GR+C PCH CKG C GPG DC
Sbjct: 180 GRSCPPCHEVCKGRCWGPGSEDC 202
>BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein.
Length = 331
Score = 237 bits (579), Expect = 3e-61
Identities = 123/306 (40%), Positives = 171/306 (55%), Gaps = 25/306 (8%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+SV + + Y+ L + C V GNLE+ L + DLSFL++IREVTGYVL++ +
Sbjct: 36 LSVTGDAENQYQTLYKLYERCEVVMGNLEIV-LTGHNADLSFLQWIREVTGYVLVAMNEF 94
Query: 61 HKIVLPQLQIIRGRTLFKLNVREEEFALLVTMS-------TAFTLELPALRDVLQGSVGI 113
+ LP L+++RG ++ + +FA+ V ++ L L L ++L G V I
Sbjct: 95 STLPLPNLRVVRGTQVY-----DGKFAIFVMLNYNTNSSHALRQLRLTQLTEILSGGVYI 149
Query: 114 YSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPARWAAGESIENCQK 171
N LCH+ TI+W +I +D ++ G+ V + W G E+CQ
Sbjct: 150 EKNDKLCHMDTIDWRDIVRDRDA---EIVVKDNGRSCPPCHEVCKGRCWGPGS--EDCQT 204
Query: 172 FSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQECPSMQ 231
+KTIC+PQC G CFGPNP CC+ CAGGC+GP T C ACR+F D G C CP
Sbjct: 205 LTKTICAPQC-NGHCFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPL 263
Query: 232 IYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAV--NG--ECIPC 287
+YN T+ EPNP+ KY YG CV +CP + + D +CVR+CPP+K V NG C PC
Sbjct: 264 VYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPC 323
Query: 288 VGTCPK 293
G CPK
Sbjct: 324 GGLCPK 329
Score = 99 bits (238), Expect = 6e-20
Identities = 61/206 (29%), Positives = 94/206 (45%), Gaps = 24/206 (11%)
Query: 350 LEVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXX 409
L +REVTGY+ V + F++L NL V+ G QV + FA ++
Sbjct: 74 LSFLQWIREVTGYVLVAMNE--FSTLP-LPNLRVVRGTQVYDGKFAIFVMLNYNTNSSHA 130
Query: 410 ------XXXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNL 463
+ SG + I +N LC+ D I W +V+ +D + +++ NG R C +
Sbjct: 131 LRQLRLTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG--RSCPPCHE 188
Query: 464 VCDPQCSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGC 523
VC +C WGPG + C + IC C+ H + + C CH EC GC
Sbjct: 189 VCKGRC-----WGPGSEDCQTLTK----TICAPQCNGH--CFGPNPNQC--CHDECAGGC 235
Query: 524 TGASRANCTSCKHVRDGPYCVAQCPE 549
+G +C +C+H D CV +CP+
Sbjct: 236 SGPQDTDCFACRHFNDSGACVPRCPQ 261
Score = 41.5 bits (93), Expect = 0.021
Identities = 25/76 (32%), Positives = 33/76 (43%), Gaps = 11/76 (14%)
Query: 628 ACRKCHPLCI-KCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK 686
+C CH +C +C G G + CQ QC C + C CH EC
Sbjct: 182 SCPPCHEVCKGRCWGPGSED--CQTLTKTICAPQCNGHCFGPN-----PNQC--CHDECA 232
Query: 687 G-CTGPGPTDCIKCKN 701
G C+GP TDC C++
Sbjct: 233 GGCSGPQDTDCFACRH 248
Score = 40.3 bits (90), Expect = 0.048
Identities = 15/23 (65%), Positives = 16/23 (69%), Gaps = 1/23 (4%)
Query: 675 GRNCTPCHSECKG-CTGPGPTDC 696
GR+C PCH CKG C GPG DC
Sbjct: 180 GRSCPPCHEVCKGRCWGPGSEDC 202
>BC128419-1|AAI28420.1| 388|Homo sapiens OSGIN2 protein protein.
Length = 388
Score = 221 bits (541), Expect = 1e-56
Identities = 119/325 (36%), Positives = 164/325 (50%), Gaps = 29/325 (8%)
Query: 244 PNGKYAYGATCVRNCPE-HLLKDNGACVRSCPPNKTAVNGE----CIPCVGTCPKTCRA- 297
P GKY++GATCV+ CP +++ D+G+CVR+C + + + C C G C K C
Sbjct: 9 PEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGI 68
Query: 298 -------EKPIHSGNIDSFKDCTIIDGSIEILEMTFTGFQQVNQDYSFGERYPKMEPDAL 350
I++ NI FK+CT I G + IL + F G SF P ++P L
Sbjct: 69 GIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGD-------SFTHT-PPLDPQEL 120
Query: 351 EVFSTVREVTGYLNVQAHHPNFTSLSYFRNLEVIGGRQVVENLFASLYIVKTXXXXXXXX 410
++ TV+E+TG+L +QA N T L F NLE+I GR F SL +V
Sbjct: 121 DILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQF-SLAVVSLNITSLGLR 179
Query: 411 XXXXVNSGAIAIMENRNLCYADKIAWNKLVKSKDHKQIIQKNGDPRQCEKNNLVCDPQCS 470
++ G + I N+NLCYA+ I W KL + K I N C+ VC CS
Sbjct: 180 SLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCS 239
Query: 471 ADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLD-----GC 523
+GCWGP P C+SC+N + G C+D C++ G + ++ C QCH ECL C
Sbjct: 240 PEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITC 299
Query: 524 TGASRANCTSCKHVRDGPYCVAQCP 548
TG NC C H DGP+CV CP
Sbjct: 300 TGRGPDNCIQCAHYIDGPHCVKTCP 324
Score = 74.1 bits (174), Expect = 3e-12
Identities = 82/313 (26%), Positives = 127/313 (40%), Gaps = 48/313 (15%)
Query: 18 FTNCTYVDGNLEL--------TWLENESMD---LSFLKYIREVTGYVLISHVKVHKIVL- 65
F NCT + G+L + ++ +D L LK ++E+TG++LI ++ L
Sbjct: 87 FKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLH 146
Query: 66 --PQLQIIRGRTLFKLNVREEEFALLVTMSTAFTLELPALRDVLQGSVGIYSNFNLCHVK 123
L+IIRGRT + +F+L V +L L +L+++ G V I N NLC+
Sbjct: 147 AFENLEIIRGRTK-----QHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYAN 201
Query: 124 TINWDEINQDLTQVTFTFIILPLGKGNARVVTQPAR--------WAAG-ESIENCQKFSK 174
TINW ++ Q T II G+ + + Q W +C+ S+
Sbjct: 202 TINWKKLFGTSGQKTK--IISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSR 259
Query: 175 -TICSPQC----AQGRCFGPNPRDC--CNTFCAGG-----CTGPLPTQCLACRNFYDEGT 222
C +C + R F N +C C+ C CTG P C+ C ++ D
Sbjct: 260 GRECVDKCNLLEGEPREFVENS-ECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPH 318
Query: 223 CSQECPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCPEHLLKDNGACVRSCPPNKTAVNG 282
C + CP+ + T W+ G + C NC G + CP N +
Sbjct: 319 CVKTCPAGVMGENNTLVWKYADAGHVCH--LCHPNCTYGC---TGPGLEGCPTNGPKIPS 373
Query: 283 ECIPCVGTCPKTC 295
VGT P C
Sbjct: 374 IATGMVGTTPLAC 386
Score = 50.4 bits (115), Expect = 4e-05
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 16/94 (17%)
Query: 453 GDPRQCEKNN--LVCDPQCSADG----CWGPGPDQCLSCQNYNFGEICIDNCSV------ 500
G+PR+ +N+ + C P+C C G GPD C+ C +Y G C+ C
Sbjct: 272 GEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGEN 331
Query: 501 HPGLYK---ADHKSCKQCHSECLDGCTGASRANC 531
+ ++K A H C CH C GCTG C
Sbjct: 332 NTLVWKYADAGHV-CHLCHPNCTYGCTGPGLEGC 364
Score = 47.6 bits (108), Expect = 3e-04
Identities = 29/87 (33%), Positives = 37/87 (42%), Gaps = 9/87 (10%)
Query: 622 EGKVKIACRKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECP-SDHFTDEIGRN--C 678
E K + CH LC +G + C C RG +C D+C + E N C
Sbjct: 224 ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSEC 283
Query: 679 TPCHSECK------GCTGPGPTDCIKC 699
CH EC CTG GP +CI+C
Sbjct: 284 IQCHPECLPQAMNITCTGRGPDNCIQC 310
Score = 39.5 bits (88), Expect = 0.083
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 619 KPLEGKVKIACRKCHPLC------IKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTD 672
+P E C +CHP C I C G G C C + G C CP+ +
Sbjct: 273 EPREFVENSECIQCHPECLPQAMNITCTGRGPDN--CIQCAHYIDGPHCVKTCPAGVMGE 330
Query: 673 ---------EIGRNCTPCHSECK-GCTGPGPTDC 696
+ G C CH C GCTGPG C
Sbjct: 331 NNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 364
Score = 35.5 bits (78), Expect = 1.4
Identities = 12/24 (50%), Positives = 17/24 (70%), Gaps = 2/24 (8%)
Query: 681 CHSEC--KGCTGPGPTDCIKCKNL 702
CH+ C +GC GP P DC+ C+N+
Sbjct: 234 CHALCSPEGCWGPEPRDCVSCRNV 257
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 294 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 347
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 348 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 408 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 465
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 525
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 526 PADRPSFAETHQAFETMFHD 545
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 294 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 347
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 348 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 408 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 465
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 525
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 526 PADRPSFAETHQAFETMFHD 545
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 307 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 360
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 361 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 420
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 421 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 478
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 479 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 538
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 539 PADRPSFAETHQAFETMFHD 558
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 279 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 332
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 333 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 393 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 450
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 451 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 510
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 511 PADRPSFAETHQAFETMFHD 530
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 294 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 347
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 348 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 408 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 465
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 525
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 526 PADRPSFAETHQAFETMFHD 545
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 279 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 332
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 333 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 393 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 450
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 451 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 510
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 511 PADRPSFAETHQAFETMFHD 530
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 294 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 347
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 348 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 408 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 465
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 525
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 526 PADRPSFAETHQAFETMFHD 545
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 279 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 332
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 333 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 393 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 450
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 451 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 510
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 511 PADRPSFAETHQAFETMFHD 530
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 294 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 347
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 348 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 407
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 408 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 465
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 466 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 525
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 526 PADRPSFAETHQAFETMFHD 545
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 216 bits (527), Expect = 5e-55
Identities = 113/260 (43%), Positives = 157/260 (60%), Gaps = 11/260 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G +G+VY GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QL
Sbjct: 279 LGGGQYGEVYVGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQL 332
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L VC + ++T+ MP G L+DY+R ++E++ + L TQI+ M YLE+K +H
Sbjct: 333 LGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQISSAMEYLEKKNFIH 392
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHK 1014
RDLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ K
Sbjct: 393 RDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNTFSIK 450
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVWAFGV +WEI +YG PY I V +L+E G ++ QP C +Y +M +CW
Sbjct: 451 SDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPPKVYELMRACWKWS 510
Query: 1075 ADSRPTFKQLADTFAEMARD 1094
RP+F + F M D
Sbjct: 511 PADRPSFAETHQAFETMFHD 530
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 222 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 276
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 277 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 334
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 335 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 392
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 393 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 452
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 453 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 222 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 276
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 277 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 334
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 335 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 392
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 393 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 452
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 453 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 241 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 295
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 296 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 353
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 354 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 411
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 412 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 471
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 472 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 518
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 222 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 276
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 277 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 334
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 335 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 392
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 393 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYELL 452
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 453 EKDYRMKRPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 241 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 295
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 296 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 353
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 354 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 411
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 412 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 471
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 472 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 518
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 241 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 295
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 296 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 353
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 354 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 411
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 412 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 471
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 472 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 518
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 241 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 295
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 296 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 353
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 354 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 411
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 412 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 471
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 472 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 518
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 241 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 295
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 296 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 353
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 354 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 411
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 412 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 471
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 472 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 518
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 222 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 276
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 277 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 334
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 335 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 392
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 393 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 452
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 453 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 499
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 214 bits (522), Expect = 2e-54
Identities = 116/287 (40%), Positives = 169/287 (58%), Gaps = 14/287 (4%)
Query: 813 RPT--NVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKET 870
+PT V PN K + + ++ LG G +G+VY+GVW + + VA+K LKE
Sbjct: 259 KPTVYGVSPNYDKWEM-ERTDITMKHKLGGGQYGEVYEGVW----KKYSLTVAVKTLKED 313
Query: 871 TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEK 928
T +EFL+EA +M ++HPNL+QLL VC +IT+ M G L+DY+R ++++
Sbjct: 314 T--MEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQE 371
Query: 929 IGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE 988
+ + L TQI+ M YLE+K +HRDLAARN LV + VK+ DFGL++L+ D
Sbjct: 372 VNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT 429
Query: 989 YKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELI 1047
Y A AG K PIKW A E + + F+ KSDVWAFGV +WEI +YG PY I V EL+
Sbjct: 430 YTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELL 489
Query: 1048 ENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
E ++ +P C +Y +M +CW + RP+F ++ F M ++
Sbjct: 490 EKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQE 536
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase protein.
Length = 1052
Score = 213 bits (520), Expect = 4e-54
Identities = 105/270 (38%), Positives = 161/270 (59%), Gaps = 3/270 (1%)
Query: 815 TNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGAN 874
T P+ I +E + G +G G FG V++G+++ EN + VAIK K T +
Sbjct: 406 TYTMPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDS 463
Query: 875 TSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL+EA M +HP++++L+ V N + +I +L LG L +++ K + +
Sbjct: 464 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 523
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG 994
+ + Q++ +AYLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ G
Sbjct: 524 ILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKG 582
Query: 995 KMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLP 1054
K+PIKW+A E I R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP
Sbjct: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
Query: 1055 QPSICTLDIYCVMVSCWMLDADSRPTFKQL 1084
P C +Y +M CW D RP F +L
Sbjct: 643 MPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 213 bits (520), Expect = 4e-54
Identities = 105/270 (38%), Positives = 161/270 (59%), Gaps = 3/270 (1%)
Query: 815 TNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGAN 874
T P+ I +E + G +G G FG V++G+++ EN + VAIK K T +
Sbjct: 406 TYTMPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDS 463
Query: 875 TSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL+EA M +HP++++L+ V N + +I +L LG L +++ K + +
Sbjct: 464 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 523
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG 994
+ + Q++ +AYLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ G
Sbjct: 524 ILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKG 582
Query: 995 KMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLP 1054
K+PIKW+A E I R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP
Sbjct: 583 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 642
Query: 1055 QPSICTLDIYCVMVSCWMLDADSRPTFKQL 1084
P C +Y +M CW D RP F +L
Sbjct: 643 MPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 213 bits (520), Expect = 4e-54
Identities = 105/270 (38%), Positives = 161/270 (59%), Gaps = 3/270 (1%)
Query: 815 TNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGAN 874
T P+ I +E + G +G G FG V++G+++ EN + VAIK K T +
Sbjct: 34 TYTMPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDS 91
Query: 875 TSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL+EA M +HP++++L+ V N + +I +L LG L +++ K + +
Sbjct: 92 VREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASL 151
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG 994
+ + Q++ +AYLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ G
Sbjct: 152 ILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKG 210
Query: 995 KMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLP 1054
K+PIKW+A E I R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP
Sbjct: 211 KLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLP 270
Query: 1055 QPSICTLDIYCVMVSCWMLDADSRPTFKQL 1084
P C +Y +M CW D RP F +L
Sbjct: 271 MPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 300
>AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens cDNA
FLJ37680 fis, clone BRHIP2012923, highly similar to FOCAL
ADHESION KINASE 1 (EC 2.7.1.112). ).
Length = 720
Score = 213 bits (519), Expect = 5e-54
Identities = 101/258 (39%), Positives = 157/258 (60%), Gaps = 2/258 (0%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
++ + G +G G FG V++G+++ EN + VAIK K T + ++FL+EA M
Sbjct: 85 IQRERIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDSVREKFLQEALTM 143
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMA 946
+HP++++L+ V N + +I +L LG L +++ K + + + + Q++ +A
Sbjct: 144 RQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 203
Query: 947 YLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECI 1006
YLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ GK+PIKW+A E I
Sbjct: 204 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESI 262
Query: 1007 QHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCV 1066
R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP P C +Y +
Sbjct: 263 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL 322
Query: 1067 MVSCWMLDADSRPTFKQL 1084
M CW D RP F +L
Sbjct: 323 MTKCWAYDPSRRPRFTEL 340
>AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine kinase
2 isoform b variant protein.
Length = 1007
Score = 213 bits (519), Expect = 5e-54
Identities = 101/258 (39%), Positives = 157/258 (60%), Gaps = 2/258 (0%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
++ + G +G G FG V++G+++ EN + VAIK K T + ++FL+EA M
Sbjct: 369 IQRERIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDSVREKFLQEALTM 427
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMA 946
+HP++++L+ V N + +I +L LG L +++ K + + + + Q++ +A
Sbjct: 428 RQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 487
Query: 947 YLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECI 1006
YLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ GK+PIKW+A E I
Sbjct: 488 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESI 546
Query: 1007 QHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCV 1066
R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP P C +Y +
Sbjct: 547 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL 606
Query: 1067 MVSCWMLDADSRPTFKQL 1084
M CW D RP F +L
Sbjct: 607 MTKCWAYDPSRRPRFTEL 624
>AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine kinase
2 isoform b variant protein.
Length = 975
Score = 213 bits (519), Expect = 5e-54
Identities = 101/258 (39%), Positives = 157/258 (60%), Gaps = 2/258 (0%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
++ + G +G G FG V++G+++ EN + VAIK K T + ++FL+EA M
Sbjct: 337 IQRERIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDSVREKFLQEALTM 395
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMA 946
+HP++++L+ V N + +I +L LG L +++ K + + + + Q++ +A
Sbjct: 396 RQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALA 455
Query: 947 YLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECI 1006
YLE KR VHRD+AARNVLV + + VK+ DFGL++ ++ + YKA+ GK+PIKW+A E I
Sbjct: 456 YLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESI 514
Query: 1007 QHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCV 1066
R FT SDVW FGV +WEIL +G +P++ + +V IENG +LP P C +Y +
Sbjct: 515 NFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSL 574
Query: 1067 MVSCWMLDADSRPTFKQL 1084
M CW D RP F +L
Sbjct: 575 MTKCWAYDPSRRPRFTEL 592
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 210 bits (512), Expect = 4e-53
Identities = 133/387 (34%), Positives = 197/387 (50%), Gaps = 16/387 (4%)
Query: 745 PYCSEHANDIPTATARTSTVLVIILVIASLFLAVLAIIG---YNFRQKAKAKKEAVKMTM 801
P+ +H +R T I+ VI L L ++G + R+ + +++ +
Sbjct: 526 PFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRA 585
Query: 802 VLTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVP 853
ED L+P P L +E + L ++G G FG+VY+G
Sbjct: 586 TDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 645
Query: 854 EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQL 912
++ K VAIK LK+T+ FL EA IM HP++L L V + +M+IT+
Sbjct: 646 PSQDCKT-VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEF 704
Query: 913 MPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVK 972
M G L ++R ++++ + IA GM YL VHRDLAARN+LV K
Sbjct: 705 MENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCK 764
Query: 973 ITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGA 1032
++DFGL +LLD + Y+ GGK+PI+W A E I HRIFT SDVW+FG+ +WE+LS+G
Sbjct: 765 VSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
Query: 1033 RPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
+PY +S + V + IE+G +LP P C +Y +M +CW D RP F++L ++
Sbjct: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
Query: 1093 RDPGRYLVIPG-DKFM--RLPSYSTQD 1116
+P I D M RLPS S D
Sbjct: 885 ANPHSLRTIANFDPRMTLRLPSLSGSD 911
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 210 bits (512), Expect = 4e-53
Identities = 109/259 (42%), Positives = 157/259 (60%), Gaps = 11/259 (4%)
Query: 839 GFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLL 898
G G +G+VY+GVW + + VA+K LKE T +EFL+EA +M ++HPNL+QLL
Sbjct: 68 GGGQYGEVYEGVW----KKYSLTVAVKTLKEDT--MEVEEFLKEAAVMKEIKHPNLVQLL 121
Query: 899 AVCMTNQ-MMLITQLMPLGCLVDYVRT-HKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC +IT+ M G L+DY+R +++++ + L TQI+ M YLE+K +HR
Sbjct: 122 GVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHR 181
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV + VK+ DFGL++L+ D Y A AG K PIKW A E + + F+ KS
Sbjct: 182 DLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKFPIKWTAPESLAYNKFSIKS 239
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVWAFGV +WEI +YG PY I V EL+E ++ +P C +Y +M +CW +
Sbjct: 240 DVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNP 299
Query: 1076 DSRPTFKQLADTFAEMARD 1094
RP+F ++ F M ++
Sbjct: 300 SDRPSFAEIHQAFETMFQE 318
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 209 bits (510), Expect = 6e-53
Identities = 131/387 (33%), Positives = 196/387 (50%), Gaps = 16/387 (4%)
Query: 745 PYCSEHANDIPTATARTSTVLVIILVIASLFLAVLAIIG---YNFRQKAKAKKEAVKMTM 801
P+ +H +R T I+ VI L L ++G + R+ + +++ +
Sbjct: 241 PFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRA 300
Query: 802 VLTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVP 853
ED L+P P L +E + L ++G G FG+VY+G
Sbjct: 301 TDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 360
Query: 854 EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQL 912
++ K VAIK LK+T+ FL EA IM HP++L L V + +M+IT+
Sbjct: 361 PSQDCKT-VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEF 419
Query: 913 MPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVK 972
M G L ++R ++++ + IA GM YL VHRDLAARN+LV K
Sbjct: 420 MENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCK 479
Query: 973 ITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGA 1032
++DFGL +LLD + Y+ GGK+PI+W A E I HRIFT SDVW+FG+ +WE+LS+G
Sbjct: 480 VSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 539
Query: 1033 RPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
+PY +S + V + IE+G +LP P C +Y +M +CW D RP F++L ++
Sbjct: 540 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 599
Query: 1093 RDPGRYLVIPG---DKFMRLPSYSTQD 1116
+P I +RLPS S D
Sbjct: 600 ANPHSLRTIANFDPRVTLRLPSLSGSD 626
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 209 bits (510), Expect = 6e-53
Identities = 131/387 (33%), Positives = 196/387 (50%), Gaps = 16/387 (4%)
Query: 745 PYCSEHANDIPTATARTSTVLVIILVIASLFLAVLAIIG---YNFRQKAKAKKEAVKMTM 801
P+ +H +R T I+ VI L L ++G + R+ + +++ +
Sbjct: 526 PFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRA 585
Query: 802 VLTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVP 853
ED L+P P L +E + L ++G G FG+VY+G
Sbjct: 586 TDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 645
Query: 854 EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQL 912
++ K VAIK LK+T+ FL EA IM HP++L L V + +M+IT+
Sbjct: 646 PSQDCKT-VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEF 704
Query: 913 MPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVK 972
M G L ++R ++++ + IA GM YL VHRDLAARN+LV K
Sbjct: 705 MENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCK 764
Query: 973 ITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGA 1032
++DFGL +LLD + Y+ GGK+PI+W A E I HRIFT SDVW+FG+ +WE+LS+G
Sbjct: 765 VSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
Query: 1033 RPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
+PY +S + V + IE+G +LP P C +Y +M +CW D RP F++L ++
Sbjct: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
Query: 1093 RDPGRYLVIPG---DKFMRLPSYSTQD 1116
+P I +RLPS S D
Sbjct: 885 ANPHSLRTIANFDPRVTLRLPSLSGSD 911
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 209 bits (510), Expect = 6e-53
Identities = 131/387 (33%), Positives = 196/387 (50%), Gaps = 16/387 (4%)
Query: 745 PYCSEHANDIPTATARTSTVLVIILVIASLFLAVLAIIG---YNFRQKAKAKKEAVKMTM 801
P+ +H +R T I+ VI L L ++G + R+ + +++ +
Sbjct: 526 PFSPDHEFRTSPPVSRGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRA 585
Query: 802 VLTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVP 853
ED L+P P L +E + L ++G G FG+VY+G
Sbjct: 586 TDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRL 645
Query: 854 EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQL 912
++ K VAIK LK+T+ FL EA IM HP++L L V + +M+IT+
Sbjct: 646 PSQDCKT-VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEF 704
Query: 913 MPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVK 972
M G L ++R ++++ + IA GM YL VHRDLAARN+LV K
Sbjct: 705 MENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCK 764
Query: 973 ITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGA 1032
++DFGL +LLD + Y+ GGK+PI+W A E I HRIFT SDVW+FG+ +WE+LS+G
Sbjct: 765 VSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGD 824
Query: 1033 RPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
+PY +S + V + IE+G +LP P C +Y +M +CW D RP F++L ++
Sbjct: 825 KPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLL 884
Query: 1093 RDPGRYLVIPG---DKFMRLPSYSTQD 1116
+P I +RLPS S D
Sbjct: 885 ANPHSLRTIANFDPRVTLRLPSLSGSD 911
>L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kinase
protein.
Length = 1036
Score = 208 bits (508), Expect = 1e-52
Identities = 113/285 (39%), Positives = 158/285 (55%), Gaps = 7/285 (2%)
Query: 811 PLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVW-VPEGENVKIPVAIKVLKE 869
P P P + ++ E +LR LG G+FG V +G W P G+ V VA+K LK
Sbjct: 105 PGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVS--VAVKCLKP 162
Query: 870 T--TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKE 927
+ +F+ E M S++H NL++L V +T M ++T+L PLG L+D +R H+
Sbjct: 163 DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQG 222
Query: 928 KIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINED 987
+ Q+A GM YLE KR +HRDLAARN+L+ T + VKI DFGL + L N+D
Sbjct: 223 HFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD 282
Query: 988 EY-KAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPEL 1046
Y K+P W A E ++ R F+H SD W FGVT+WE+ +YG P+ ++ +
Sbjct: 283 HYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHK 342
Query: 1047 IE-NGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAE 1090
I+ G +LP+P C DIY VMV CW + RPTF L D E
Sbjct: 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLE 387
>BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein.
Length = 528
Score = 208 bits (508), Expect = 1e-52
Identities = 113/285 (39%), Positives = 158/285 (55%), Gaps = 7/285 (2%)
Query: 811 PLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVW-VPEGENVKIPVAIKVLKE 869
P P P + ++ E +LR LG G+FG V +G W P G+ V VA+K LK
Sbjct: 105 PGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVS--VAVKCLKP 162
Query: 870 T--TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKE 927
+ +F+ E M S++H NL++L V +T M ++T+L PLG L+D +R H+
Sbjct: 163 DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQG 222
Query: 928 KIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINED 987
+ Q+A GM YLE KR +HRDLAARN+L+ T + VKI DFGL + L N+D
Sbjct: 223 HFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD 282
Query: 988 EY-KAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPEL 1046
Y K+P W A E ++ R F+H SD W FGVT+WE+ +YG P+ ++ +
Sbjct: 283 HYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHK 342
Query: 1047 IE-NGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAE 1090
I+ G +LP+P C DIY VMV CW + RPTF L D E
Sbjct: 343 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLE 387
>AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens cDNA
FLJ16772 fis, clone BRAWH3043827, highly similar to Homo
sapiens activated p21cdc42Hs kinase (ACK1). ).
Length = 1086
Score = 208 bits (508), Expect = 1e-52
Identities = 113/285 (39%), Positives = 158/285 (55%), Gaps = 7/285 (2%)
Query: 811 PLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVW-VPEGENVKIPVAIKVLKE 869
P P P + ++ E +LR LG G+FG V +G W P G+ V VA+K LK
Sbjct: 168 PGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDAPSGKTVS--VAVKCLKP 225
Query: 870 T--TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKE 927
+ +F+ E M S++H NL++L V +T M ++T+L PLG L+D +R H+
Sbjct: 226 DVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQG 285
Query: 928 KIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINED 987
+ Q+A GM YLE KR +HRDLAARN+L+ T + VKI DFGL + L N+D
Sbjct: 286 HFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDD 345
Query: 988 EY-KAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPEL 1046
Y K+P W A E ++ R F+H SD W FGVT+WE+ +YG P+ ++ +
Sbjct: 346 HYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHK 405
Query: 1047 IE-NGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAE 1090
I+ G +LP+P C DIY VMV CW + RPTF L D E
Sbjct: 406 IDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLE 450
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 206 bits (502), Expect = 6e-52
Identities = 128/386 (33%), Positives = 192/386 (49%), Gaps = 13/386 (3%)
Query: 723 TCPDNIPNKIYFDEQLQDPIEEPYCSEHANDIPTATARTSTVLVII--LVIASLFLAVLA 780
T D P+ Y + E ++ T + S L +I + + + L VLA
Sbjct: 493 TLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLA 552
Query: 781 IIGYNFRQKAKAKKEAVKMTMV-LTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE--- 831
+G+ ++ K ++ V + E +PL+ T PN A L+ E
Sbjct: 553 GVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSC 612
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
+ R ++G G FG+VYKG+ ++PVAIK LK +FL EA IM H
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSH 672
Query: 892 PNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEE 950
N+++L V + MM+IT+ M G L ++R + + IA GM YL
Sbjct: 673 HNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLAN 732
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAGGKMPIKWLALECIQHR 1009
VHRDLAARN+LV + K++DFGL+++L D E Y +GGK+PI+W A E I +R
Sbjct: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYR 792
Query: 1010 IFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVS 1069
FT SDVW+FG+ +WE+++YG RPY +S V + I +G +LP P C IY +M+
Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQ 852
Query: 1070 CWMLDADSRPTFKQLADTFAEMARDP 1095
CW + RP F + ++ R P
Sbjct: 853 CWQQERARRPKFADIVSILDKLIRAP 878
Score = 33.9 bits (74), Expect = 4.1
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 4/65 (6%)
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLDGCTGA 526
C+ DG W QCL Y E CS PG +K A C +C L GA
Sbjct: 247 CAVDGEWLVPIGQCLCQAGYEKVEDACQACS--PGFFKFEASESPCLECPEHTLPSPEGA 304
Query: 527 SRANC 531
+ C
Sbjct: 305 TSCEC 309
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 206 bits (502), Expect = 6e-52
Identities = 128/386 (33%), Positives = 192/386 (49%), Gaps = 13/386 (3%)
Query: 723 TCPDNIPNKIYFDEQLQDPIEEPYCSEHANDIPTATARTSTVLVII--LVIASLFLAVLA 780
T D P+ Y + E ++ T + S L +I + + + L VLA
Sbjct: 493 TLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLA 552
Query: 781 IIGYNFRQKAKAKKEAVKMTMV-LTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE--- 831
+G+ ++ K ++ V + E +PL+ T PN A L+ E
Sbjct: 553 GVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSC 612
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
+ R ++G G FG+VYKG+ ++PVAIK LK +FL EA IM H
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSH 672
Query: 892 PNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEE 950
N+++L V + MM+IT+ M G L ++R + + IA GM YL
Sbjct: 673 HNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLAN 732
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAGGKMPIKWLALECIQHR 1009
VHRDLAARN+LV + K++DFGL+++L D E Y +GGK+PI+W A E I +R
Sbjct: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYR 792
Query: 1010 IFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVS 1069
FT SDVW+FG+ +WE+++YG RPY +S V + I +G +LP P C IY +M+
Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQ 852
Query: 1070 CWMLDADSRPTFKQLADTFAEMARDP 1095
CW + RP F + ++ R P
Sbjct: 853 CWQQERARRPKFADIVSILDKLIRAP 878
Score = 33.9 bits (74), Expect = 4.1
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 4/65 (6%)
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLDGCTGA 526
C+ DG W QCL Y E CS PG +K A C +C L GA
Sbjct: 247 CAVDGEWLVPIGQCLCQAGYEKVEDACQACS--PGFFKFEASESPCLECPEHTLPSPEGA 304
Query: 527 SRANC 531
+ C
Sbjct: 305 TSCEC 309
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 206 bits (502), Expect = 6e-52
Identities = 128/386 (33%), Positives = 192/386 (49%), Gaps = 13/386 (3%)
Query: 723 TCPDNIPNKIYFDEQLQDPIEEPYCSEHANDIPTATARTSTVLVII--LVIASLFLAVLA 780
T D P+ Y + E ++ T + S L +I + + + L VLA
Sbjct: 493 TLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGGVAVGVVLLLVLA 552
Query: 781 IIGYNFRQKAKAKKEAVKMTMV-LTGCEDNEPLRP-----TNVKPNLAKLRIVKEAE--- 831
+G+ ++ K ++ V + E +PL+ T PN A L+ E
Sbjct: 553 GVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQAVLKFTTEIHPSC 612
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
+ R ++G G FG+VYKG+ ++PVAIK LK +FL EA IM H
Sbjct: 613 VTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMGQFSH 672
Query: 892 PNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEE 950
N+++L V + MM+IT+ M G L ++R + + IA GM YL
Sbjct: 673 HNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLAN 732
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAGGKMPIKWLALECIQHR 1009
VHRDLAARN+LV + K++DFGL+++L D E Y +GGK+PI+W A E I +R
Sbjct: 733 MNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRWTAPEAISYR 792
Query: 1010 IFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVS 1069
FT SDVW+FG+ +WE+++YG RPY +S V + I +G +LP P C IY +M+
Sbjct: 793 KFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQ 852
Query: 1070 CWMLDADSRPTFKQLADTFAEMARDP 1095
CW + RP F + ++ R P
Sbjct: 853 CWQQERARRPKFADIVSILDKLIRAP 878
Score = 33.9 bits (74), Expect = 4.1
Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 4/65 (6%)
Query: 469 CSADGCWGPGPDQCLSCQNYNFGEICIDNCSVHPGLYK--ADHKSCKQCHSECLDGCTGA 526
C+ DG W QCL Y E CS PG +K A C +C L GA
Sbjct: 247 CAVDGEWLVPIGQCLCQAGYEKVEDACQACS--PGFFKFEASESPCLECPEHTLPSPEGA 304
Query: 527 SRANC 531
+ C
Sbjct: 305 TSCEC 309
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 205 bits (501), Expect = 8e-52
Identities = 111/284 (39%), Positives = 160/284 (56%), Gaps = 5/284 (1%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG+VY+G ++ K VAIK LK+T+ FL EA IM HP++L
Sbjct: 637 VIGEGEFGEVYRGTLRLPSQDCKT-VAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILH 695
Query: 897 LLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
L V + +M+IT+ M L ++R ++++ + IA GM YL VH
Sbjct: 696 LEGVVTKRKPIMIITEFMENAALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVH 755
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKS 1015
RDLAARN+LV K++DFGL +LLD + Y+ GGK+PI+W A E I HRIFT S
Sbjct: 756 RDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTAS 815
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ +WE+LS+G +PY +S + V + IE+G +LP P C +Y +M +CW D
Sbjct: 816 DVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDR 875
Query: 1076 DSRPTFKQLADTFAEMARDPGRYLVIPG---DKFMRLPSYSTQD 1116
RP F++L ++ +P I +RLPS S D
Sbjct: 876 ARRPHFQKLQAHLEQLLANPHSLRTIANFDPRVTLRLPSLSGSD 919
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 205 bits (500), Expect = 1e-51
Identities = 106/251 (42%), Positives = 155/251 (61%), Gaps = 11/251 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V++G+W N PVA+K LK G+ +FL EA IM ++ HP L+QL
Sbjct: 240 LGSGQFGEVWEGLW-----NNTTPVAVKTLKP--GSMDPNDFLREAQIMKNLRHPKLIQL 292
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AVC + + + +IT+LM G L +Y++ KI ++ Q+A GMAYLE + +H
Sbjct: 293 YAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIH 352
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDI-NEDEYKAAGG-KMPIKWLALECIQHRIFTH 1013
RDLAARNVLV N K+ DFGLA++ + NED Y++ K+P+KW A E I+ F+
Sbjct: 353 RDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSI 412
Query: 1014 KSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWML 1073
KSDVW+FG+ ++EI++YG PY ++ V +++ +LPQPS C Y +M+ CW
Sbjct: 413 KSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472
Query: 1074 DADSRPTFKQL 1084
+ RPTF+ L
Sbjct: 473 EPKERPTFETL 483
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 205 bits (500), Expect = 1e-51
Identities = 106/251 (42%), Positives = 155/251 (61%), Gaps = 11/251 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V++G+W N PVA+K LK G+ +FL EA IM ++ HP L+QL
Sbjct: 240 LGSGQFGEVWEGLW-----NNTTPVAVKTLKP--GSMDPNDFLREAQIMKNLRHPKLIQL 292
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AVC + + + +IT+LM G L +Y++ KI ++ Q+A GMAYLE + +H
Sbjct: 293 YAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIH 352
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDI-NEDEYKAAGG-KMPIKWLALECIQHRIFTH 1013
RDLAARNVLV N K+ DFGLA++ + NED Y++ K+P+KW A E I+ F+
Sbjct: 353 RDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSI 412
Query: 1014 KSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWML 1073
KSDVW+FG+ ++EI++YG PY ++ V +++ +LPQPS C Y +M+ CW
Sbjct: 413 KSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472
Query: 1074 DADSRPTFKQL 1084
+ RPTF+ L
Sbjct: 473 EPKERPTFETL 483
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 205 bits (500), Expect = 1e-51
Identities = 106/251 (42%), Positives = 155/251 (61%), Gaps = 11/251 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V++G+W N PVA+K LK G+ +FL EA IM ++ HP L+QL
Sbjct: 240 LGSGQFGEVWEGLW-----NNTTPVAVKTLKP--GSMDPNDFLREAQIMKNLRHPKLIQL 292
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AVC + + + +IT+LM G L +Y++ KI ++ Q+A GMAYLE + +H
Sbjct: 293 YAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIH 352
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDI-NEDEYKAAGG-KMPIKWLALECIQHRIFTH 1013
RDLAARNVLV N K+ DFGLA++ + NED Y++ K+P+KW A E I+ F+
Sbjct: 353 RDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSI 412
Query: 1014 KSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWML 1073
KSDVW+FG+ ++EI++YG PY ++ V +++ +LPQPS C Y +M+ CW
Sbjct: 413 KSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472
Query: 1074 DADSRPTFKQL 1084
+ RPTF+ L
Sbjct: 473 EPKERPTFETL 483
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 205 bits (500), Expect = 1e-51
Identities = 106/251 (42%), Positives = 155/251 (61%), Gaps = 11/251 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V++G+W N PVA+K LK G+ +FL EA IM ++ HP L+QL
Sbjct: 240 LGSGQFGEVWEGLW-----NNTTPVAVKTLKP--GSMDPNDFLREAQIMKNLRHPKLIQL 292
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AVC + + + +IT+LM G L +Y++ KI ++ Q+A GMAYLE + +H
Sbjct: 293 YAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIH 352
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDI-NEDEYKAAGG-KMPIKWLALECIQHRIFTH 1013
RDLAARNVLV N K+ DFGLA++ + NED Y++ K+P+KW A E I+ F+
Sbjct: 353 RDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSI 412
Query: 1014 KSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWML 1073
KSDVW+FG+ ++EI++YG PY ++ V +++ +LPQPS C Y +M+ CW
Sbjct: 413 KSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472
Query: 1074 DADSRPTFKQL 1084
+ RPTF+ L
Sbjct: 473 EPKERPTFETL 483
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase protein.
Length = 505
Score = 205 bits (500), Expect = 1e-51
Identities = 106/251 (42%), Positives = 155/251 (61%), Gaps = 11/251 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V++G+W N PVA+K LK G+ +FL EA IM ++ HP L+QL
Sbjct: 240 LGSGQFGEVWEGLW-----NNTTPVAVKTLKP--GSMDPNDFLREAQIMKNLRHPKLIQL 292
Query: 898 LAVC-MTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AVC + + + +IT+LM G L +Y++ KI ++ Q+A GMAYLE + +H
Sbjct: 293 YAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLESRNYIH 352
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDI-NEDEYKAAGG-KMPIKWLALECIQHRIFTH 1013
RDLAARNVLV N K+ DFGLA++ + NED Y++ K+P+KW A E I+ F+
Sbjct: 353 RDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEAIRSNKFSI 412
Query: 1014 KSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWML 1073
KSDVW+FG+ ++EI++YG PY ++ V +++ +LPQPS C Y +M+ CW
Sbjct: 413 KSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNA 472
Query: 1074 DADSRPTFKQL 1084
+ RPTF+ L
Sbjct: 473 EPKERPTFETL 483
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 204 bits (498), Expect = 2e-51
Identities = 115/348 (33%), Positives = 190/348 (54%), Gaps = 12/348 (3%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQKAKAKK-----EAVKMTMVLTGCEDNEPLRPTN 816
S + IIL+ +++ + GY + A K+ +K+ + T + + PT
Sbjct: 548 SAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQ 607
Query: 817 VKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKG-VWVPEGENVKIPVAIKVLKETTGANT 875
AK + + ++G G FG+V G + +P + +I VAIK LK
Sbjct: 608 AVHEFAKELDATNISIDK--VVGAGEFGEVCSGRLKLPSKK--EISVAIKTLKVGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M++T+ M G L ++R H +
Sbjct: 664 RRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 724 VGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 783
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W + E I +R FT SDVW++G+ +WE++SYG RPY +S ++V + ++ G +L
Sbjct: 784 GKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRL 843
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
P P C +Y +M+ CW D ++RP F+Q+ ++ R+PG +I
Sbjct: 844 PPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKII 891
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 204 bits (498), Expect = 2e-51
Identities = 115/348 (33%), Positives = 190/348 (54%), Gaps = 12/348 (3%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQKAKAKK-----EAVKMTMVLTGCEDNEPLRPTN 816
S + IIL+ +++ + GY + A K+ +K+ + T + + PT
Sbjct: 548 SAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQ 607
Query: 817 VKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKG-VWVPEGENVKIPVAIKVLKETTGANT 875
AK + + ++G G FG+V G + +P + +I VAIK LK
Sbjct: 608 TVHEFAKELDATNISIDK--VVGAGEFGEVCSGRLKLPSKK--EISVAIKTLKVGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M++T+ M G L ++R H +
Sbjct: 664 RRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 724 VGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 783
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W + E I +R FT SDVW++G+ +WE++SYG RPY +S ++V + ++ G +L
Sbjct: 784 GKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRL 843
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
P P C +Y +M+ CW D ++RP F+Q+ ++ R+PG +I
Sbjct: 844 PPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKII 891
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 204 bits (498), Expect = 2e-51
Identities = 115/348 (33%), Positives = 190/348 (54%), Gaps = 12/348 (3%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQKAKAKK-----EAVKMTMVLTGCEDNEPLRPTN 816
S + IIL+ +++ + GY + A K+ +K+ + T + + PT
Sbjct: 548 SAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPHTYEDPTQ 607
Query: 817 VKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKG-VWVPEGENVKIPVAIKVLKETTGANT 875
AK + + ++G G FG+V G + +P + +I VAIK LK
Sbjct: 608 AVHEFAKELDATNISIDK--VVGAGEFGEVCSGRLKLPSKK--EISVAIKTLKVGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M++T+ M G L ++R H +
Sbjct: 664 RRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 724 VGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 783
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W + E I +R FT SDVW++G+ +WE++SYG RPY +S ++V + ++ G +L
Sbjct: 784 GKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRL 843
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
P P C +Y +M+ CW D ++RP F+Q+ ++ R+PG +I
Sbjct: 844 PPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKII 891
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 203 bits (495), Expect = 4e-51
Identities = 108/284 (38%), Positives = 169/284 (59%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+VYKG G+ +I VAIK LK
Sbjct: 592 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKR-EIYVAIKTLKAGYSEKQ 650
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M+IT+ M G L ++R + +
Sbjct: 651 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 710
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+LV + K++DFGL++ L D ++ Y ++
Sbjct: 711 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 770
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+P++W A E I +R FT SDVW++G+ +WE++S+G RPY ++S ++V IE
Sbjct: 771 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIRMWEVMSFGERPYWDMSNQDVINAIEQDY 830
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P+ C ++ +M+ CW D +SRP F ++ +T +M R+P
Sbjct: 831 RLPPPTDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNP 874
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 202 bits (494), Expect = 5e-51
Identities = 108/284 (38%), Positives = 168/284 (59%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+VYKG G+ +I VAIK LK
Sbjct: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKR-EIYVAIKTLKAGYSEKQ 661
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M+IT+ M G L ++R + +
Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+LV + K++DFGL++ L D ++ Y ++
Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+P++W A E I +R FT SDVW++G+ +WE++S+G RPY ++S ++V IE
Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D +SRP F ++ +T +M R+P
Sbjct: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNP 885
>U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta
protein.
Length = 1009
Score = 201 bits (491), Expect = 1e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGLFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 201 bits (491), Expect = 1e-50
Identities = 107/284 (37%), Positives = 168/284 (59%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+VYKG G+ +I VAIK LK
Sbjct: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKR-EIYVAIKTLKAGYSEKQ 661
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M+IT+ M G L ++R + +
Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+L+ + K++DFGL++ L D ++ Y ++
Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILLNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+P++W A E I +R FT SDVW++G+ +WE++S+G RPY ++S ++V IE
Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D +SRP F ++ +T +M R+P
Sbjct: 842 RLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNP 885
>U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein.
Length = 1009
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal
tyrosine kinase protein.
Length = 1009
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase protein.
Length = 1009
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine
kinase 2 beta protein.
Length = 1009
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 430 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 488
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 489 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 548
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 549 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 607
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 608 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 667
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 668 DRPRFTELVCSLSDV 682
>AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens cDNA
FLJ46514 fis, clone THYMU3032798, highly similar to
Focal adhesion kinase 2 (EC 2.7.1.112). ).
Length = 596
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 176 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 234
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 235 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 294
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 295 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 353
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 354 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 413
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 414 DRPRFTELVCSLSDV 428
>AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine
kinase 2 beta isoform a variant protein.
Length = 802
Score = 201 bits (490), Expect = 2e-50
Identities = 96/255 (37%), Positives = 157/255 (61%), Gaps = 2/255 (0%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
+LG G FG+VY+GV+ + KI VA+K K+ + ++F+ EA IM +++HP++++
Sbjct: 435 ILGEGFFGEVYEGVYTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVK 493
Query: 897 LLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
L+ + +I +L P G L Y+ +K + + + QI + MAYLE VHR
Sbjct: 494 LIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHR 553
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSD 1016
D+A RN+LV +P VK+ DFGL++ ++ +ED YKA+ ++PIKW++ E I R FT SD
Sbjct: 554 DIAVRNILVASPECVKLGDFGLSRYIE-DEDYYKASVTRLPIKWMSPESINFRRFTTASD 612
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW F V +WEILS+G +P+ + ++V ++E G +LP+P +C +Y +M CW D
Sbjct: 613 VWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPS 672
Query: 1077 SRPTFKQLADTFAEM 1091
RP F +L + +++
Sbjct: 673 DRPRFTELVCSLSDV 687
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 406 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 458
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 459 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 518
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 519 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 576
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 577 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 636
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 637 DERPTFKILLSNILDV 652
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 986
Score = 200 bits (488), Expect = 3e-50
Identities = 121/344 (35%), Positives = 189/344 (54%), Gaps = 14/344 (4%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLTGCEDN-EPLRPTN 816
STVL ++ V S+ L V+ I + ++ +KAK+EA + + G +P T
Sbjct: 546 STVL-LVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF--TY 602
Query: 817 VKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGA 873
PN A KE + ++ ++G G FG+V G G+ +I VAIK LK
Sbjct: 603 EDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKAGYTD 661
Query: 874 NTSKEFLEEAYIMASVEHPNLLQLLAVCMT-NQMMLITQLMPLGCLVDYVRTHKEKIGSK 932
++FL EA IM +HPN++ L V +M+IT+ M G L ++R + +
Sbjct: 662 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
Query: 933 AFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKA 991
+ I GM YL + VHRDLAARN+LV + K++DFG++++L D E Y
Sbjct: 722 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
Query: 992 AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G
Sbjct: 782 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C + ++ +M+ CW + RP F Q+ + ++ R+P
Sbjct: 842 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNP 885
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4
protein.
Length = 986
Score = 200 bits (488), Expect = 3e-50
Identities = 121/344 (35%), Positives = 189/344 (54%), Gaps = 14/344 (4%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLTGCEDN-EPLRPTN 816
STVL ++ V S+ L V+ I + ++ +KAK+EA + + G +P T
Sbjct: 546 STVL-LVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF--TY 602
Query: 817 VKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGA 873
PN A KE + ++ ++G G FG+V G G+ +I VAIK LK
Sbjct: 603 EDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKAGYTD 661
Query: 874 NTSKEFLEEAYIMASVEHPNLLQLLAVCMT-NQMMLITQLMPLGCLVDYVRTHKEKIGSK 932
++FL EA IM +HPN++ L V +M+IT+ M G L ++R + +
Sbjct: 662 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
Query: 933 AFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKA 991
+ I GM YL + VHRDLAARN+LV + K++DFG++++L D E Y
Sbjct: 722 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
Query: 992 AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G
Sbjct: 782 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C + ++ +M+ CW + RP F Q+ + ++ R+P
Sbjct: 842 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNP 885
>BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein.
Length = 986
Score = 200 bits (488), Expect = 3e-50
Identities = 121/344 (35%), Positives = 189/344 (54%), Gaps = 14/344 (4%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLTGCEDN-EPLRPTN 816
STVL ++ V S+ L V+ I + ++ +KAK+EA + + G +P T
Sbjct: 546 STVL-LVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF--TY 602
Query: 817 VKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGA 873
PN A KE + ++ ++G G FG+V G G+ +I VAIK LK
Sbjct: 603 EDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKAGYTD 661
Query: 874 NTSKEFLEEAYIMASVEHPNLLQLLAVCMT-NQMMLITQLMPLGCLVDYVRTHKEKIGSK 932
++FL EA IM +HPN++ L V +M+IT+ M G L ++R + +
Sbjct: 662 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
Query: 933 AFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKA 991
+ I GM YL + VHRDLAARN+LV + K++DFG++++L D E Y
Sbjct: 722 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
Query: 992 AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G
Sbjct: 782 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C + ++ +M+ CW + RP F Q+ + ++ R+P
Sbjct: 842 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNP 885
>BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein.
Length = 949
Score = 200 bits (488), Expect = 3e-50
Identities = 121/344 (35%), Positives = 189/344 (54%), Gaps = 14/344 (4%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLTGCEDN-EPLRPTN 816
STVL ++ V S+ L V+ I + ++ +KAK+EA + + G +P T
Sbjct: 546 STVL-LVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF--TY 602
Query: 817 VKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGA 873
PN A KE + ++ ++G G FG+V G G+ +I VAIK LK
Sbjct: 603 EDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKAGYTD 661
Query: 874 NTSKEFLEEAYIMASVEHPNLLQLLAVCMT-NQMMLITQLMPLGCLVDYVRTHKEKIGSK 932
++FL EA IM +HPN++ L V +M+IT+ M G L ++R + +
Sbjct: 662 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 721
Query: 933 AFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKA 991
+ I GM YL + VHRDLAARN+LV + K++DFG++++L D E Y
Sbjct: 722 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 781
Query: 992 AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G
Sbjct: 782 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C + ++ +M+ CW + RP F Q+ + ++ R+P
Sbjct: 842 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNP 885
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 200 bits (488), Expect = 3e-50
Identities = 103/256 (40%), Positives = 151/256 (58%), Gaps = 11/256 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V G W G+ VAIK++KE G+ + EF+EEA +M ++ H L+QL
Sbjct: 408 LGTGQFGVVKYGKW--RGQ---YDVAIKMIKE--GSMSEDEFIEEAKVMMNLSHEKLVQL 460
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC + + +IT+ M GCL++Y+R + + ++ L C + M YLE K+ +HR
Sbjct: 461 YGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHR 520
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV VK++DFGL++ + +DEY ++ G K P++W E + + F+ KS
Sbjct: 521 DLAARNCLVNDQGVVKVSDFGLSRY--VLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKS 578
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
D+WAFGV +WEI S G PYE + E I GL+L +P + + +Y +M SCW A
Sbjct: 579 DIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKA 638
Query: 1076 DSRPTFKQLADTFAEM 1091
D RPTFK L ++
Sbjct: 639 DERPTFKILLSNILDV 654
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 200 bits (488), Expect = 3e-50
Identities = 107/284 (37%), Positives = 168/284 (59%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+VYKG G+ +I VAIK LK
Sbjct: 603 PNEAVREFAKEIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKR-EIYVAIKTLKAGYSEKQ 661
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M+IT+ M G L ++R + +
Sbjct: 662 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQL 721
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+LV + K++DFGL++ L D ++ Y ++
Sbjct: 722 VGMLRGIAAGMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSS 781
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+P++W A E I +R FT SDVW++G+ +WE++ +G RPY ++S ++V IE
Sbjct: 782 LGGKIPVRWTAPEAIAYRKFTSASDVWSYGIHMWEVMYFGERPYWDMSNQDVINAIEQDY 841
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P+ C ++ +M+ CW D +SRP F ++ +T +M R+P
Sbjct: 842 RLPPPTDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNP 885
>AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein.
Length = 711
Score = 200 bits (488), Expect = 3e-50
Identities = 121/344 (35%), Positives = 189/344 (54%), Gaps = 14/344 (4%)
Query: 762 STVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLTGCEDN-EPLRPTN 816
STVL ++ V S+ L V+ I + ++ +KAK+EA + + G +P T
Sbjct: 271 STVL-LVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF--TY 327
Query: 817 VKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGA 873
PN A KE + ++ ++G G FG+V G G+ +I VAIK LK
Sbjct: 328 EDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKR-EICVAIKTLKAGYTD 386
Query: 874 NTSKEFLEEAYIMASVEHPNLLQLLAVCMT-NQMMLITQLMPLGCLVDYVRTHKEKIGSK 932
++FL EA IM +HPN++ L V +M+IT+ M G L ++R + +
Sbjct: 387 KQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVI 446
Query: 933 AFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKA 991
+ I GM YL + VHRDLAARN+LV + K++DFG++++L D E Y
Sbjct: 447 QLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTT 506
Query: 992 AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G
Sbjct: 507 RGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGY 566
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C + ++ +M+ CW + RP F Q+ + ++ R+P
Sbjct: 567 RLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNP 610
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 200 bits (487), Expect = 4e-50
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 11/269 (4%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +EL +G G FG V+ G W+ + + VAIK ++E GA + ++F+EEA +
Sbjct: 357 VIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
M + HP L+QL VC+ + L+ + M GCL DY+RT + ++ L C + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG-KMPIKWLAL 1003
MAYLEE ++HRDLAARN LV +K++DFG+ + + +D+Y ++ G K P+KW +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF--VLDDQYTSSTGTKFPVKWASP 527
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E ++ KSDVW+FGV +WE+ S G PYEN S V E I G +L +P + + +
Sbjct: 528 EVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHV 587
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
Y +M CW + RP F +L AE+A
Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 200 bits (487), Expect = 4e-50
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 11/269 (4%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +EL +G G FG V+ G W+ + + VAIK ++E GA + ++F+EEA +
Sbjct: 357 VIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
M + HP L+QL VC+ + L+ + M GCL DY+RT + ++ L C + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG-KMPIKWLAL 1003
MAYLEE ++HRDLAARN LV +K++DFG+ + + +D+Y ++ G K P+KW +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF--VLDDQYTSSTGTKFPVKWASP 527
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E ++ KSDVW+FGV +WE+ S G PYEN S V E I G +L +P + + +
Sbjct: 528 EVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHV 587
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
Y +M CW + RP F +L AE+A
Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 200 bits (487), Expect = 4e-50
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 11/269 (4%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +EL +G G FG V+ G W+ + + VAIK ++E GA + ++F+EEA +
Sbjct: 357 VIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
M + HP L+QL VC+ + L+ + M GCL DY+RT + ++ L C + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG-KMPIKWLAL 1003
MAYLEE ++HRDLAARN LV +K++DFG+ + + +D+Y ++ G K P+KW +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF--VLDDQYTSSTGTKFPVKWASP 527
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E ++ KSDVW+FGV +WE+ S G PYEN S V E I G +L +P + + +
Sbjct: 528 EVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHV 587
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
Y +M CW + RP F +L AE+A
Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell kinase
protein.
Length = 620
Score = 200 bits (487), Expect = 4e-50
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 11/269 (4%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +EL +G G FG V+ G W+ + + VAIK ++E GA + ++F+EEA +
Sbjct: 357 VIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
M + HP L+QL VC+ + L+ + M GCL DY+RT + ++ L C + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG-KMPIKWLAL 1003
MAYLEE ++HRDLAARN LV +K++DFG+ + + +D+Y ++ G K P+KW +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF--VLDDQYTSSTGTKFPVKWASP 527
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E ++ KSDVW+FGV +WE+ S G PYEN S V E I G +L +P + + +
Sbjct: 528 EVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHV 587
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
Y +M CW + RP F +L AE+A
Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell kinase
protein.
Length = 620
Score = 200 bits (487), Expect = 4e-50
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 11/269 (4%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +EL +G G FG V+ G W+ + + VAIK ++E GA + ++F+EEA +
Sbjct: 357 VIDPSELTFVQEIGSGQFGLVHLGYWLNKDK-----VAIKTIRE--GAMSEEDFIEEAEV 409
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
M + HP L+QL VC+ + L+ + M GCL DY+RT + ++ L C + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG-KMPIKWLAL 1003
MAYLEE ++HRDLAARN LV +K++DFG+ + + +D+Y ++ G K P+KW +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF--VLDDQYTSSTGTKFPVKWASP 527
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E ++ KSDVW+FGV +WE+ S G PYEN S V E I G +L +P + + +
Sbjct: 528 EVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTHV 587
Query: 1064 YCVMVSCWMLDADSRPTFKQLADTFAEMA 1092
Y +M CW + RP F +L AE+A
Sbjct: 588 YQIMNHCWKERPEDRPAFSRLLRQLAEIA 616
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 664
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 665 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 723
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 724 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 783
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 784 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 887
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 664
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 665 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 723
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 724 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 783
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 784 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 887
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 404 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 463
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 464 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 522
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 523 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 581
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 582 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 641
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 642 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 701
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 702 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 745
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 664
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 665 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 723
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 724 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 783
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 784 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 887
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 664
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 665 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 723
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 724 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 783
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 784 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 887
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 546 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 605
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 606 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 664
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 665 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 723
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 724 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 783
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 784 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 843
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 844 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 887
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 198 bits (484), Expect = 9e-50
Identities = 117/344 (34%), Positives = 185/344 (53%), Gaps = 11/344 (3%)
Query: 767 IILVIASLFLAVLAIIGYNFRQKAKAKKEAVKMTMVLTGCEDNEPLRP-TNVKPNLAKLR 825
++ V+ L + V+A++ + + + + K L G + P T PN A
Sbjct: 545 VVGVVLVLVVIVVAVLCLRKQSNGREAEYSDKHGQYLIGHGTKVYIDPFTYEDPNEAVRE 604
Query: 826 IVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEE 882
KE ++ + ++G G FG+V +G G+ VAIK LK +EFL E
Sbjct: 605 FAKEIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESC-VAIKTLKGGYTERQRREFLSE 663
Query: 883 AYIMASVEHPNLLQLLAVCMTNQM--MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQ 940
A IM EHPN+++L V +TN M M++T+ M G L ++R + + +
Sbjct: 664 ASIMGQFEHPNIIRLEGV-VTNSMPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRG 722
Query: 941 IARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE--YKAA-GGKMP 997
IA GM YL E VHRDLAARN+LV + K++DFGL++ L+ N + Y ++ GGK+P
Sbjct: 723 IASGMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIP 782
Query: 998 IKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPS 1057
I+W A E I R FT SD W++G+ +WE++S+G RPY ++S ++V IE +LP P
Sbjct: 783 IRWTAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPP 842
Query: 1058 ICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
C ++ +M+ CW D ++RP F Q+ +M R+P ++
Sbjct: 843 DCPTSLHQLMLDCWQKDRNARPRFPQVVSALDKMIRNPASLKIV 886
>BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associated
protein kinase 70kDa protein.
Length = 619
Score = 198 bits (483), Expect = 1e-49
Identities = 100/245 (40%), Positives = 147/245 (60%), Gaps = 3/245 (1%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V +GV+ +I VAIKVLK+ T ++E + EA IM +++P +++L
Sbjct: 344 LGCGNFGSVRQGVY--RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRL 401
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRD 957
+ VC +ML+ ++ G L ++ +E+I Q++ GM YLEEK VHRD
Sbjct: 402 IGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRD 461
Query: 958 LAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHKSD 1016
LAARNVL+ + KI+DFGL+K L ++ Y A + GK P+KW A ECI R F+ +SD
Sbjct: 462 LAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSD 521
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW++GVT+WE LSYG +PY+ + V IE G ++ P C ++Y +M CW+ +
Sbjct: 522 VWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWE 581
Query: 1077 SRPTF 1081
RP F
Sbjct: 582 DRPDF 586
>BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein.
Length = 493
Score = 198 bits (483), Expect = 1e-49
Identities = 100/245 (40%), Positives = 147/245 (60%), Gaps = 3/245 (1%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V +GV+ +I VAIKVLK+ T ++E + EA IM +++P +++L
Sbjct: 218 LGCGNFGSVRQGVY--RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRL 275
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRD 957
+ VC +ML+ ++ G L ++ +E+I Q++ GM YLEEK VHRD
Sbjct: 276 IGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRD 335
Query: 958 LAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHKSD 1016
LAARNVL+ + KI+DFGL+K L ++ Y A + GK P+KW A ECI R F+ +SD
Sbjct: 336 LAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSD 395
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW++GVT+WE LSYG +PY+ + V IE G ++ P C ++Y +M CW+ +
Sbjct: 396 VWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWE 455
Query: 1077 SRPTF 1081
RP F
Sbjct: 456 DRPDF 460
>AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein.
Length = 493
Score = 198 bits (483), Expect = 1e-49
Identities = 100/245 (40%), Positives = 147/245 (60%), Gaps = 3/245 (1%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V +GV+ +I VAIKVLK+ T ++E + EA IM +++P +++L
Sbjct: 218 LGCGNFGSVRQGVY--RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRL 275
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRD 957
+ VC +ML+ ++ G L ++ +E+I Q++ GM YLEEK VHRD
Sbjct: 276 IGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRD 335
Query: 958 LAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHKSD 1016
LAARNVL+ + KI+DFGL+K L ++ Y A + GK P+KW A ECI R F+ +SD
Sbjct: 336 LAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSD 395
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW++GVT+WE LSYG +PY+ + V IE G ++ P C ++Y +M CW+ +
Sbjct: 396 VWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWE 455
Query: 1077 SRPTF 1081
RP F
Sbjct: 456 DRPDF 460
>AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase
protein.
Length = 312
Score = 198 bits (483), Expect = 1e-49
Identities = 100/245 (40%), Positives = 147/245 (60%), Gaps = 3/245 (1%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V +GV+ +I VAIKVLK+ T ++E + EA IM +++P +++L
Sbjct: 37 LGCGNFGSVRQGVY--RMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRL 94
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRD 957
+ VC +ML+ ++ G L ++ +E+I Q++ GM YLEEK VHRD
Sbjct: 95 IGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRD 154
Query: 958 LAARNVLVQTPNSVKITDFGLAKLLDINEDEYKA-AGGKMPIKWLALECIQHRIFTHKSD 1016
LAARNVL+ + KI+DFGL+K L ++ Y A + GK P+KW A ECI R F+ +SD
Sbjct: 155 LAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSD 214
Query: 1017 VWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDAD 1076
VW++GVT+WE LSYG +PY+ + V IE G ++ P C ++Y +M CW+ +
Sbjct: 215 VWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWE 274
Query: 1077 SRPTF 1081
RP F
Sbjct: 275 DRPDF 279
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine kinase
protein.
Length = 478
Score = 197 bits (481), Expect = 2e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 97 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 155
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 156 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 215
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 216 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 275
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 276 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 335
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 336 RLPPPMDCPAALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 379
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 197 bits (481), Expect = 2e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 600 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 658
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 659 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 718
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 719 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 778
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 779 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 838
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 839 RLPPPMDCPAALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 882
>AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein.
Length = 1005
Score = 197 bits (481), Expect = 2e-49
Identities = 102/273 (37%), Positives = 154/273 (56%), Gaps = 3/273 (1%)
Query: 825 RIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAY 884
R ++ + + ++G G G+V G G+ +PVAIK LK ++FL EA
Sbjct: 628 REIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR-DVPVAIKALKAGYTERQRRDFLSEAS 686
Query: 885 IMASVEHPNLLQLLAVCMTNQM-MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIAR 943
IM +HPN+++L V ++ M++T+ M G L ++RTH + + +
Sbjct: 687 IMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGA 746
Query: 944 GMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE-YKAAGGKMPIKWLA 1002
GM YL + VHRDLAARNVLV + K++DFGL+++L+ + D Y GGK+PI+W A
Sbjct: 747 GMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTA 806
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E I R F+ SDVW+FGV +WE+L+YG RPY N++ R+V +E G +LP P C
Sbjct: 807 PEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHA 866
Query: 1063 IYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
++ +M+ CW D RP F Q+ + R P
Sbjct: 867 LHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSP 899
>AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein.
Length = 419
Score = 197 bits (481), Expect = 2e-49
Identities = 118/320 (36%), Positives = 168/320 (52%), Gaps = 25/320 (7%)
Query: 1 MSVPSNRDTHYRNLRDRFTNCTYVDGNLELTWLENESMDLSFLKYIREVTGYVLISHVKV 60
+ +P++ +TH LR + C V GNLELT+L + LSFL+ I+EV GYVLI+H +V
Sbjct: 33 LRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNA-SLSFLQDIQEVQGYVLIAHNQV 91
Query: 61 HKIVLPQLQIIRGRTLFKLN----VREEEFALLVTMSTAFT-------LELPALRDVLQG 109
++ L +L+I+RG LF+ N V + L T L+L +L ++L+G
Sbjct: 92 RQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKG 151
Query: 110 SVGIYSNFNLCHVKTINWDEINQDLTQVTFTFIILPLGKG--NARVVTQPAR-WAAGESI 166
V I N LC+ TI W +I Q+ T I + + + +R W GES
Sbjct: 152 GVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCW--GESS 209
Query: 167 ENCQKFSKTICSPQCAQGRCFGPNPRDCCNTFCAGGCTGPLPTQCLACRNFYDEGTCSQE 226
E+CQ ++T+C+ CA RC GP P DCC+ CA GCTGP + CLAC +F G C
Sbjct: 210 EDCQSLTRTVCAGGCA--RCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELH 267
Query: 227 CPSMQIYNPTTYSWEPNPNGKYAYGATCVRNCP-EHLLKDNGACVRSCPPNKTAVNGE-- 283
CP++ YN T+ PNP G+Y +GA+CV CP +L D G+C CP + V E
Sbjct: 268 CPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDG 327
Query: 284 ---CIPCVGTCPKTCRAEKP 300
C C C + + P
Sbjct: 328 TQRCEKCSKPCARGTHSLPP 347
Score = 70.9 bits (166), Expect = 3e-11
Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 14/132 (10%)
Query: 418 GAIAIMENRNLCYADKIAWNKLVKSKDHKQI-IQKNGDPRQCEKNNLVCDPQCSADGCWG 476
G + I N LCY D I W + + + + R C C P C CWG
Sbjct: 151 GGVLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHP----CSPMCKGSRCWG 206
Query: 477 PGPDQCLSCQNYNFGEICIDNCSVHPGLYKADHKSCKQCHSECLDGCTGASRANCTSCKH 536
+ C S +C C+ G D C CH +C GCTG ++C +C H
Sbjct: 207 ESSEDCQSLTR----TVCAGGCARCKGPLPTD---C--CHEQCAAGCTGPKHSDCLACLH 257
Query: 537 VRDGPYCVAQCP 548
C CP
Sbjct: 258 FNHSGICELHCP 269
Score = 38.3 bits (85), Expect = 0.19
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 6/71 (8%)
Query: 630 RKCHPLCIKCVGFGIHEQVCQVCNGFKRGDQCEDECPSDHFTDEIGRNCTPCHSECK-GC 688
R CHP C G + + C R C C + +C CH +C GC
Sbjct: 190 RACHPCSPMCKGSRCWGESSEDCQSLTR-TVCAGGCA--RCKGPLPTDC--CHEQCAAGC 244
Query: 689 TGPGPTDCIKC 699
TGP +DC+ C
Sbjct: 245 TGPKHSDCLAC 255
>AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein.
Length = 853
Score = 197 bits (481), Expect = 2e-49
Identities = 102/273 (37%), Positives = 154/273 (56%), Gaps = 3/273 (1%)
Query: 825 RIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAY 884
R ++ + + ++G G G+V G G+ +PVAIK LK ++FL EA
Sbjct: 476 REIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR-DVPVAIKALKAGYTERQRRDFLSEAS 534
Query: 885 IMASVEHPNLLQLLAVCMTNQM-MLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIAR 943
IM +HPN+++L V ++ M++T+ M G L ++RTH + + +
Sbjct: 535 IMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGA 594
Query: 944 GMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDE-YKAAGGKMPIKWLA 1002
GM YL + VHRDLAARNVLV + K++DFGL+++L+ + D Y GGK+PI+W A
Sbjct: 595 GMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTA 654
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E I R F+ SDVW+FGV +WE+L+YG RPY N++ R+V +E G +LP P C
Sbjct: 655 PEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHA 714
Query: 1063 IYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
++ +M+ CW D RP F Q+ + R P
Sbjct: 715 LHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSP 747
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 606 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 664
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 665 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 724
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 725 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 844
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 845 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 888
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 197 bits (480), Expect = 3e-49
Identities = 103/257 (40%), Positives = 150/257 (58%), Gaps = 11/257 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
+G G FG V+ G W I VAIK + E G+ + ++F+EEA +M + H L+QL
Sbjct: 277 IGSGQFGVVHLGEW-----RSHIQVAIKAINE--GSMSEEDFIEEAKVMMKLSHSKLVQL 329
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC+ + + ++T+ M GCL++Y+R +K K+ + L+ C I GM YLE +HR
Sbjct: 330 YGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGMEYLERNGYIHR 389
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV + VKI+DFG+ + + +DEY ++ G K PIKW E ++ KS
Sbjct: 390 DLAARNCLVSSTCIVKISDFGMTRY--VLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKS 447
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FGV +WE+ + G P+EN S V E I G +L +P + + IY VM SCW
Sbjct: 448 DVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKP 507
Query: 1076 DSRPTFKQLADTFAEMA 1092
+ RPTF +L E+A
Sbjct: 508 EGRPTFAELLRAVTEIA 524
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 606 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 664
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 665 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 724
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 725 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 844
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 845 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 888
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 600 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 658
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 659 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 718
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 719 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 778
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 779 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 838
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 839 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 882
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 606 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 664
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 665 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 724
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 725 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 844
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 845 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 888
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 606 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 664
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 665 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 724
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 725 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 784
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 785 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 844
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 845 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 888
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 600 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 658
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 659 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 718
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 719 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 778
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 779 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 838
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 839 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 882
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 605 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 663
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 664 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 723
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 724 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 783
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 784 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 843
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 844 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 887
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 197 bits (480), Expect = 3e-49
Identities = 108/284 (38%), Positives = 164/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 623 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 681
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 682 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 741
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 742 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 801
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 802 LGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 861
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 862 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 905
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 196 bits (479), Expect = 4e-49
Identities = 103/257 (40%), Positives = 150/257 (58%), Gaps = 11/257 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
+G G FG V+ G W I VAIK + E G+ + ++F+EEA +M + H L+QL
Sbjct: 277 IGSGQFGVVHLGEW-----RSHIQVAIKAINE--GSMSEEDFIEEAKVMMKLSHSKLVQL 329
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
VC+ + + ++T+ M GCL++Y+R +K K+ + L+ C I GM YLE +HR
Sbjct: 330 YGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQXICEGMEYLERNGYIHR 389
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DLAARN LV + VKI+DFG+ + + +DEY ++ G K PIKW E ++ KS
Sbjct: 390 DLAARNCLVSSTCIVKISDFGMTRY--VLDDEYVSSFGAKFPIKWSPPEVFLFNKYSSKS 447
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FGV +WE+ + G P+EN S V E I G +L +P + + IY VM SCW
Sbjct: 448 DVWSFGVLMWEVFTEGKMPFENKSNLQVVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKP 507
Query: 1076 DSRPTFKQLADTFAEMA 1092
+ RPTF +L E+A
Sbjct: 508 EGRPTFAELLRAVTEIA 524
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 196 bits (479), Expect = 4e-49
Identities = 108/284 (38%), Positives = 163/284 (57%), Gaps = 8/284 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V G G+ +I VAIK LK
Sbjct: 589 PNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGKR-EIFVAIKTLKSGYTEKQ 647
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M+IT+ M G L ++R + +
Sbjct: 648 RRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFTVIQL 707
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL + VHRDLAARN+LV + K++DFGL++ L D ++ Y +A
Sbjct: 708 VGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSA 767
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK PI+W A E IQ+R FT SDVW++G+ +WE++SYG RPY +++ ++V IE
Sbjct: 768 LGGKFPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDY 827
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+LP P C ++ +M+ CW D + RP F Q+ +T +M R+P
Sbjct: 828 RLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNP 871
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 196 bits (477), Expect = 6e-49
Identities = 114/358 (31%), Positives = 190/358 (53%), Gaps = 12/358 (3%)
Query: 749 EHANDIPTATARTSTVLVIILVIASLFLAVLAIIGYNFRQK----AKAKKEAVKMTMVLT 804
E A ++ + +++ ++ +A + V + G+ ++ +KA +E +
Sbjct: 543 EEATATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF 602
Query: 805 GCEDNEP-LRP-TNVKPNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVK 859
+ + P T PN A + KE + ++ ++G G FG+V G G+
Sbjct: 603 KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-D 661
Query: 860 IPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCL 918
+ VAIK LK ++FL EA IM +HPN++ L V + +M++ + M G L
Sbjct: 662 VAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGAL 721
Query: 919 VDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGL 978
++R H + + IA GM YL + VHRDLAARN+LV + K++DFGL
Sbjct: 722 DAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGL 781
Query: 979 AKLL-DINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYEN 1037
++++ D E Y GGK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY +
Sbjct: 782 SRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 841
Query: 1038 ISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
+S ++V + IE G +LP P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 842 MSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 899
>Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase
protein.
Length = 612
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 331 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 381
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 382 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 441
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 442 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 500
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 501 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 561 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 596
>X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase
protein.
Length = 630
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 349 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 399
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 400 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 459
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 460 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 518
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 519 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 578
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 579 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 614
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase
protein.
Length = 635
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 354 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 404
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 405 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 464
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 465 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 523
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 524 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein.
Length = 612
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 331 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 381
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 382 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 441
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 442 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 500
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 501 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 561 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 596
>BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 354 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 404
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 405 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 464
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 465 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 523
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 524 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
>BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 354 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 404
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 405 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 464
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 465 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 523
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 524 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase
protein.
Length = 612
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 331 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 381
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 382 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 441
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 442 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 500
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 501 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 560
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 561 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 596
>AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 195 bits (475), Expect = 1e-48
Identities = 106/276 (38%), Positives = 160/276 (57%), Gaps = 12/276 (4%)
Query: 808 DNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVL 867
D E +RP V + KL +++ EL G G FG V KG + + + V VA+K+L
Sbjct: 354 DPEEIRPKEVYLD-RKLLTLEDKEL------GSGNFGTVKKGYY--QMKKVVKTVAVKIL 404
Query: 868 K-ETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK 926
K E E L EA +M +++P +++++ +C ML+ ++ LG L Y++ ++
Sbjct: 405 KNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNR 464
Query: 927 EKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINE 986
+ K + Q++ GM YLEE VHRDLAARNVL+ T + KI+DFGL+K L +E
Sbjct: 465 H-VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADE 523
Query: 987 DEYKA-AGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPE 1045
+ YKA GK P+KW A ECI + F+ KSDVW+FGV +WE SYG +PY + V
Sbjct: 524 NYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTA 583
Query: 1046 LIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTF 1081
++E G ++ P+ C ++Y +M CW D ++RP F
Sbjct: 584 MLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGF 619
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 195 bits (475), Expect = 1e-48
Identities = 104/282 (36%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A + KE + ++ ++G G FG+V G G+ + VAIK LK
Sbjct: 617 PNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKR-DVAVAIKTLKVGYTEKQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V + +M++ + M G L ++R H +
Sbjct: 676 RRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ IA GM YL + VHRDLAARN+LV + K++DFGL++++ D E Y G
Sbjct: 736 VGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTG 795
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+P++W A E IQ+R FT SDVW++G+ +WE++SYG RPY ++S ++V + IE G +L
Sbjct: 796 GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRL 855
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C ++ +M+ CW + RP F+Q+ +M R+P
Sbjct: 856 PAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine kinase
protein.
Length = 1037
Score = 194 bits (474), Expect = 1e-48
Identities = 102/282 (36%), Positives = 162/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE E + ++G G FG+V G G+ ++PVAIK LK
Sbjct: 659 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVGYTEKQ 717
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V ++ +M++T+ M G L +++ + +
Sbjct: 718 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 777
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ I+ GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 778 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 837
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W A E I R FT SDVW++G+ +WE++SYG RPY ++ ++V + +E G +L
Sbjct: 838 GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRL 897
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C +Y +M+ CW + +SRP F ++ + ++ R+P
Sbjct: 898 PSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNP 939
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 194 bits (474), Expect = 1e-48
Identities = 102/282 (36%), Positives = 162/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE E + ++G G FG+V G G+ ++PVAIK LK
Sbjct: 613 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVGYTEKQ 671
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V ++ +M++T+ M G L +++ + +
Sbjct: 672 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 731
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ I+ GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 732 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 791
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W A E I R FT SDVW++G+ +WE++SYG RPY ++ ++V + +E G +L
Sbjct: 792 GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRL 851
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C +Y +M+ CW + +SRP F ++ + ++ R+P
Sbjct: 852 PSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNP 893
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 194 bits (474), Expect = 1e-48
Identities = 102/282 (36%), Positives = 162/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE E + ++G G FG+V G G+ ++PVAIK LK
Sbjct: 673 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVGYTEKQ 731
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V ++ +M++T+ M G L +++ + +
Sbjct: 732 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 791
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ I+ GM YL + VHRDLAARN+L+ + K++DFGL+++L D E Y G
Sbjct: 792 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRG 851
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W A E I R FT SDVW++G+ +WE++SYG RPY ++ ++V + +E G +L
Sbjct: 852 GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRL 911
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C +Y +M+ CW + +SRP F ++ + ++ R+P
Sbjct: 912 PSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNP 953
>BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein
protein.
Length = 969
Score = 191 bits (466), Expect = 1e-47
Identities = 101/282 (35%), Positives = 161/282 (57%), Gaps = 6/282 (2%)
Query: 819 PNLAKLRIVKEAE---LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE E + ++G G FG+V G G+ ++PVAIK LK
Sbjct: 591 PNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKR-ELPVAIKTLKVGYTEKQ 649
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN++ L V ++ +M++T+ M G L +++ + +
Sbjct: 650 RRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQL 709
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL-DINEDEYKAAG 993
+ I+ GM YL + VHRDLAARN+L+ + K++DF L+++L D E Y G
Sbjct: 710 VGMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFELSRVLEDDPEAAYTTRG 769
Query: 994 GKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKL 1053
GK+PI+W A E I R FT SDVW++G+ +WE++SYG RPY ++ ++V + +E G +L
Sbjct: 770 GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRL 829
Query: 1054 PQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDP 1095
P P C +Y +M+ CW + +SRP F ++ + ++ R+P
Sbjct: 830 PSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNP 871
>X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein.
Length = 1400
Score = 191 bits (465), Expect = 2e-47
Identities = 102/281 (36%), Positives = 161/281 (57%), Gaps = 15/281 (5%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G ++ + +N +I AIK L T + FL E +M + HPN+L
Sbjct: 1087 VIGKGHFGVVYHGEYIDQAQN-RIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLA 1145
Query: 897 LLAVCMTNQMM--LITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
L+ + + + + ++ M G L+ ++R+ + K +++ Q+ARGM YL E++ V
Sbjct: 1146 LIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFV 1205
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAG----GKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ DI + EY + ++P+KW+ALE +Q
Sbjct: 1206 HRDLAARNCMLDESFTVKVADFGLAR--DILDREYYSVQQHRHARLPVKWMALESLQTYR 1263
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+L+ GA PY +I ++ + G +LPQP C +Y VM C
Sbjct: 1264 FTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQC 1323
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPGDKFMRLPS 1111
W D RPTF+ L ++ + GD +++LP+
Sbjct: 1324 WEADPAVRPTFRVLVGEVEQIVS------ALLGDHYVQLPA 1358
>AB209338-1|BAD92575.1| 400|Homo sapiens Hypothetical protein
FLJ16772 variant protein.
Length = 400
Score = 190 bits (464), Expect = 2e-47
Identities = 96/236 (40%), Positives = 136/236 (57%), Gaps = 4/236 (1%)
Query: 859 KIPVAIKVLKET--TGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLG 916
++ VA+K LK + +F+ E M S++H NL++L V +T M ++T+L PLG
Sbjct: 28 QVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLG 87
Query: 917 CLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDF 976
L+D +R H+ + Q+A GM YLE KR +HRDLAARN+L+ T + VKI DF
Sbjct: 88 SLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDF 147
Query: 977 GLAKLLDINEDEY-KAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPY 1035
GL + L N+D Y K+P W A E ++ R F+H SD W FGVT+WE+ +YG P+
Sbjct: 148 GLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPW 207
Query: 1036 ENISARNVPELIE-NGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAE 1090
++ + I+ G +LP+P C DIY VMV CW + RPTF L D E
Sbjct: 208 IGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLE 263
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 190 bits (463), Expect = 3e-47
Identities = 104/290 (35%), Positives = 166/290 (57%), Gaps = 8/290 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V +G G ++ VAIK LK
Sbjct: 617 PNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRR-EVFVAIKTLKVGYTERQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M++T+ M L ++R + +
Sbjct: 676 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+LV + K++DFGL++ L D ++ Y ++
Sbjct: 736 VGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V +E
Sbjct: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDY 855
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
+LP P C ++ +M+ CW+ D + RP F Q+ +T ++ R+ VI
Sbjct: 856 RLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVI 905
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 190 bits (463), Expect = 3e-47
Identities = 104/290 (35%), Positives = 166/290 (57%), Gaps = 8/290 (2%)
Query: 819 PNLAKLRIVKEAEL---RRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANT 875
PN A KE ++ + ++G G FG+V +G G ++ VAIK LK
Sbjct: 617 PNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRR-EVFVAIKTLKVGYTERQ 675
Query: 876 SKEFLEEAYIMASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAF 934
++FL EA IM +HPN+++L V ++ +M++T+ M L ++R + +
Sbjct: 676 RRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQL 735
Query: 935 LNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLL--DINEDEYKAA 992
+ IA GM YL E VHRDLAARN+LV + K++DFGL++ L D ++ Y ++
Sbjct: 736 VGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSS 795
Query: 993 -GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGL 1051
GGK+PI+W A E I +R FT SDVW++G+ +WE++SYG RPY ++S ++V +E
Sbjct: 796 LGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDY 855
Query: 1052 KLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARDPGRYLVI 1101
+LP P C ++ +M+ CW+ D + RP F Q+ +T ++ R+ VI
Sbjct: 856 RLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVI 905
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 190 bits (462), Expect = 4e-47
Identities = 96/254 (37%), Positives = 149/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 1083 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1141
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+GM YL K+ V
Sbjct: 1142 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV 1201
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 1202 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 1259
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 1260 FTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 1319
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 1320 WHPKAEMRPSFSEL 1333
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 190 bits (462), Expect = 4e-47
Identities = 99/260 (38%), Positives = 156/260 (60%), Gaps = 12/260 (4%)
Query: 830 AELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASV 889
+E G LG G FG+V++G+W+ +PVAIKV+K T + +E + +
Sbjct: 228 SEFALGRKLGEGYFGEVWEGLWLGS-----LPVAIKVIKSANMKLT--DLAKEIQTLKGL 280
Query: 890 EHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAY 947
H L++L AVC + + ++T+LM G L ++ T + + + L + Q+A GM+Y
Sbjct: 281 RHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSY 340
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYK-AAGGKMPIKWLALECI 1006
LEE+R+VHRDLAARNVLV + K+ DFGLA+LL +D Y ++ K+P+KW A E
Sbjct: 341 LEEQRVVHRDLAARNVLVDDGLACKVADFGLARLL--KDDIYSPSSSSKIPVKWTAPEAA 398
Query: 1007 QHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCV 1066
+R+F+ KSDVW+FGV + E+ +YG PYE ++ + I G +LP+P+ C ++Y +
Sbjct: 399 NYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRGYRLPRPAACPAEVYVL 458
Query: 1067 MVSCWMLDADSRPTFKQLAD 1086
M+ CW + RP+F L +
Sbjct: 459 MLECWRSSPEERPSFATLRE 478
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 189 bits (461), Expect = 5e-47
Identities = 96/254 (37%), Positives = 149/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 216 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 274
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+GM YL K+ V
Sbjct: 275 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV 334
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 335 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 392
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 393 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 452
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 453 WHPKAEMRPSFSEL 466
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 189 bits (461), Expect = 5e-47
Identities = 96/254 (37%), Positives = 149/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 148 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 206
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+GM YL K+ V
Sbjct: 207 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV 266
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 267 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 324
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 325 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 384
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 385 WHPKAEMRPSFSEL 398
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 189 bits (461), Expect = 5e-47
Identities = 96/254 (37%), Positives = 149/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 1083 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1141
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+GM YL K+ V
Sbjct: 1142 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV 1201
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 1202 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 1259
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 1260 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 1319
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 1320 WHPKAEMRPSFSEL 1333
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine kinase
protein.
Length = 631
Score = 189 bits (461), Expect = 5e-47
Identities = 96/267 (35%), Positives = 149/267 (55%), Gaps = 11/267 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ +EL LG G FG V G W + VAIK ++E GA ++F+EEA +M
Sbjct: 365 INPSELTFMRELGSGLFGVVRLGKW-----RAQYKVAIKAIRE--GAMCEEDFIEEAKVM 417
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L+QL VC + + ++T+ M GCL++++R + L+ C + GM
Sbjct: 418 MKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGM 477
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
YLE +HRDLAARN LV VK++DFG+A+ + +D+Y ++G K P+KW E
Sbjct: 478 EYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARY--VLDDQYTSSSGAKFPVKWCPPE 535
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ F+ KSDVW+FGV +WE+ + G P+E + V ++ G +L QP + + +Y
Sbjct: 536 VFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVY 595
Query: 1065 CVMVSCWMLDADSRPTFKQLADTFAEM 1091
VM+ CW + RP+F+ L T E+
Sbjct: 596 EVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine kinase
protein.
Length = 631
Score = 189 bits (461), Expect = 5e-47
Identities = 96/267 (35%), Positives = 149/267 (55%), Gaps = 11/267 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ +EL LG G FG V G W + VAIK ++E GA ++F+EEA +M
Sbjct: 365 INPSELTFMRELGSGLFGVVRLGKW-----RAQYKVAIKAIRE--GAMCEEDFIEEAKVM 417
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L+QL VC + + ++T+ M GCL++++R + L+ C + GM
Sbjct: 418 MKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGM 477
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
YLE +HRDLAARN LV VK++DFG+A+ + +D+Y ++G K P+KW E
Sbjct: 478 EYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARY--VLDDQYTSSSGAKFPVKWCPPE 535
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ F+ KSDVW+FGV +WE+ + G P+E + V ++ G +L QP + + +Y
Sbjct: 536 VFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVY 595
Query: 1065 CVMVSCWMLDADSRPTFKQLADTFAEM 1091
VM+ CW + RP+F+ L T E+
Sbjct: 596 EVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene precursor
variant protein.
Length = 712
Score = 189 bits (461), Expect = 5e-47
Identities = 96/254 (37%), Positives = 149/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 405 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 463
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+GM YL K+ V
Sbjct: 464 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFV 523
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 524 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 581
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 582 FTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 641
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 642 WHPKAEMRPSFSEL 655
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 188 bits (458), Expect = 1e-46
Identities = 96/267 (35%), Positives = 148/267 (55%), Gaps = 11/267 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ +EL LG G FG V G W + VAIK ++E GA ++F+EEA +M
Sbjct: 365 INPSELTFMRELGSGLFGVVRLGKW-----RAQYKVAIKAIRE--GAMCEEDFIEEAKVM 417
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L+QL VC + + ++T+ M GCL++++R + L+ C + GM
Sbjct: 418 MKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGM 477
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
YLE +HRDLAARN LV VK++DFG+A+ +D+Y ++G K P+KW E
Sbjct: 478 EYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYF--LDDQYTSSSGAKFPVKWCPPE 535
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ F+ KSDVW+FGV +WE+ + G P+E + V ++ G +L QP + + +Y
Sbjct: 536 VFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVY 595
Query: 1065 CVMVSCWMLDADSRPTFKQLADTFAEM 1091
VM+ CW + RP+F+ L T E+
Sbjct: 596 EVMLRCWQEKPEGRPSFEDLLRTIDEL 622
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 187 bits (456), Expect = 2e-46
Identities = 95/254 (37%), Positives = 148/254 (58%), Gaps = 9/254 (3%)
Query: 837 MLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQ 896
++G G FG VY G + + + KI A+K L T +FL E IM HPN+L
Sbjct: 1101 VIGRGHFGCVYHGTLL-DNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLS 1159
Query: 897 LLAVCMTNQ--MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLV 954
LL +C+ ++ +++ M G L +++R K + + Q+A+ M YL K+ V
Sbjct: 1160 LLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKAMKYLASKKFV 1219
Query: 955 HRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA----GGKMPIKWLALECIQHRI 1010
HRDLAARN ++ +VK+ DFGLA+ D+ + EY + G K+P+KW+ALE +Q +
Sbjct: 1220 HRDLAARNCMLDEKFTVKVADFGLAR--DMYDKEYYSVHNKTGAKLPVKWMALESLQTQK 1277
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+++ GA PY +++ ++ + G +L QP C +Y VM+ C
Sbjct: 1278 FTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKC 1337
Query: 1071 WMLDADSRPTFKQL 1084
W A+ RP+F +L
Sbjct: 1338 WHPKAEMRPSFSEL 1351
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 187 bits (455), Expect = 3e-46
Identities = 99/273 (36%), Positives = 153/273 (56%), Gaps = 15/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + VA+K +K T++ FL+E +M ++H
Sbjct: 235 LTLGAQIGEGEFGAVLQGEYLGQ------KVAVKNIKCDV---TAQAFLDETAVMTKMQH 285
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + +A GM YLE
Sbjct: 286 ENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLES 345
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 346 KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 400
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E G ++ P C ++ +M SC
Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSC 460
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 461 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 493
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 187 bits (455), Expect = 3e-46
Identities = 99/273 (36%), Positives = 153/273 (56%), Gaps = 15/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + VA+K +K T++ FL+E +M ++H
Sbjct: 235 LTLGAQIGEGEFGAVLQGEYLGQ------KVAVKNIKCDV---TAQAFLDETAVMTKMQH 285
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + +A GM YLE
Sbjct: 286 ENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLES 345
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 346 KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 400
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E G ++ P C ++ +M SC
Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSC 460
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 461 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 493
>D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein.
Length = 347
Score = 187 bits (455), Expect = 3e-46
Identities = 95/241 (39%), Positives = 144/241 (59%), Gaps = 4/241 (1%)
Query: 859 KIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCM-TNQMMLITQLMPLGC 917
+I VAIK LK ++FL E IM +HPN++ L V + +M+IT+ M G
Sbjct: 8 EIFVAIKTLKSGYTEKQRRDFLSERSIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGS 67
Query: 918 LVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFG 977
L ++R + + + IA GM YL + VHRDLAARN+LV + K++DFG
Sbjct: 68 LDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFG 127
Query: 978 LAKLL--DINEDEYKAA-GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARP 1034
L++ L D ++ Y +A GGK+PI+W A E IQ+R FT SDVW++G+ +WE++SYG RP
Sbjct: 128 LSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERP 187
Query: 1035 YENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQLADTFAEMARD 1094
Y +++ ++V IE +LP P C ++ +M+ CW D + RP F Q+ +T +M R+
Sbjct: 188 YWDMTNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRN 247
Query: 1095 P 1095
P
Sbjct: 248 P 248
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 187 bits (455), Expect = 3e-46
Identities = 99/273 (36%), Positives = 153/273 (56%), Gaps = 15/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + VA+K +K T++ FL+E +M ++H
Sbjct: 235 LTLGAQIGEGEFGAVLQGEYLGQ------KVAVKNIKCDV---TAQAFLDETAVMTKMQH 285
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + +A GM YLE
Sbjct: 286 ENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLES 345
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 346 KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 400
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E G ++ P C ++ +M SC
Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSC 460
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 461 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 493
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 187 bits (455), Expect = 3e-46
Identities = 99/273 (36%), Positives = 153/273 (56%), Gaps = 15/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + VA+K +K T++ FL+E +M ++H
Sbjct: 235 LTLGAQIGEGEFGAVLQGEYLGQ------KVAVKNIKCDV---TAQAFLDETAVMTKMQH 285
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + +A GM YLE
Sbjct: 286 ENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLES 345
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 346 KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 400
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E G ++ P C ++ +M SC
Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSC 460
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 461 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 493
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 187 bits (455), Expect = 3e-46
Identities = 99/273 (36%), Positives = 153/273 (56%), Gaps = 15/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + VA+K +K T++ FL+E +M ++H
Sbjct: 235 LTLGAQIGEGEFGAVLQGEYLGQ------KVAVKNIKCDV---TAQAFLDETAVMTKMQH 285
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + +A GM YLE
Sbjct: 286 ENLVRLLGVILHQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLES 345
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 346 KKLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 400
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E G ++ P C ++ +M SC
Sbjct: 401 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKGYRMEPPEGCPGPVHVLMSSC 460
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 461 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 493
>AC068970-1|AAX88856.1| 136|Homo sapiens unknown protein.
Length = 136
Score = 186 bits (452), Expect = 7e-46
Identities = 82/134 (61%), Positives = 106/134 (79%)
Query: 810 EPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKE 869
EPL P+ PN A+LRI+KE EL+R +LG GAFG VYKG+WVPEGE VKIPVAIK+L E
Sbjct: 3 EPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNE 62
Query: 870 TTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHKEKI 929
TTG + EF++EA IMAS++HP+L++LL VC++ + L+TQLMP GCL++YV HK+ I
Sbjct: 63 TTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNI 122
Query: 930 GSKAFLNWCTQIAR 943
GS+ LNWC QIA+
Sbjct: 123 GSQLLLNWCVQIAK 136
>BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 185 bits (450), Expect = 1e-45
Identities = 102/261 (39%), Positives = 151/261 (57%), Gaps = 13/261 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ LR LG G FG+V+ G + N+K VAIK LKE G + + FL EA +M
Sbjct: 236 IPRQSLRLVRKLGSGQFGEVWMGYYK---NNMK--VAIKTLKE--GTMSPEAFLGEANVM 288
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGM 945
+++H L++L AV + ++T+ M GCL+D+++T + ++ ++ QIA GM
Sbjct: 289 KALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM 348
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALE 1004
AY+E +HRDL A N+LV KI DFGLA+++D EY A G K PIKW A E
Sbjct: 349 AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIID---SEYTAQEGAKFPIKWTAPE 405
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
I +FT K+DVW+FGV + E+++YG PY +S V +E G ++P+P C ++Y
Sbjct: 406 AIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELY 465
Query: 1065 -CVMVSCWMLDADSRPTFKQL 1084
V+ CW + RPTF+ L
Sbjct: 466 RGVIAECWRSRPEERPTFEFL 486
>BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 185 bits (450), Expect = 1e-45
Identities = 102/261 (39%), Positives = 151/261 (57%), Gaps = 13/261 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ LR LG G FG+V+ G + N+K VAIK LKE G + + FL EA +M
Sbjct: 236 IPRQSLRLVRKLGSGQFGEVWMGYYK---NNMK--VAIKTLKE--GTMSPEAFLGEANVM 288
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGM 945
+++H L++L AV + ++T+ M GCL+D+++T + ++ ++ QIA GM
Sbjct: 289 KALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM 348
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALE 1004
AY+E +HRDL A N+LV KI DFGLA+++D EY A G K PIKW A E
Sbjct: 349 AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIID---SEYTAQEGAKFPIKWTAPE 405
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
I +FT K+DVW+FGV + E+++YG PY +S V +E G ++P+P C ++Y
Sbjct: 406 AIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELY 465
Query: 1065 -CVMVSCWMLDADSRPTFKQL 1084
V+ CW + RPTF+ L
Sbjct: 466 RGVIAECWRSRPEERPTFEFL 486
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 1944 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 2002
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 2003 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2062
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 2063 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2122
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 2123 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2182
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 2183 DLWNLMTQCWAQEPDQRPTFHRIQD 2207
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 1950 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 2008
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 2009 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2128
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 2129 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2188
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 2189 DLWNLMTQCWAQEPDQRPTFHRIQD 2213
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 97 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 155
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 156 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 215
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 216 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 275
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 276 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 335
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 336 DLWNLMTQCWAQEPDQRPTFHRIQD 360
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 161 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 219
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 220 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 279
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 280 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 339
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 340 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 399
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 400 DLWNLMTQCWAQEPDQRPTFHRIQD 424
>AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 1950 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 2008
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 2009 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2128
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 2129 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2188
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 2189 DLWNLMTQCWAQEPDQRPTFHRIQD 2213
>AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 184 bits (449), Expect = 2e-45
Identities = 104/265 (39%), Positives = 152/265 (57%), Gaps = 16/265 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 1944 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 2002
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 2003 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2062
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 2063 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2122
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 2123 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2182
Query: 1062 DIYCVMVSCWMLDADSRPTFKQLAD 1086
D++ +M CW + D RPTF ++ D
Sbjct: 2183 DLWNLMTQCWAQEPDQRPTFHRIQD 2207
>Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase
protein.
Length = 505
Score = 184 bits (448), Expect = 2e-45
Identities = 102/261 (39%), Positives = 151/261 (57%), Gaps = 13/261 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ LR LG G FG+V+ G + N+K VAIK LKE G + + FL EA +M
Sbjct: 236 IPRQSLRLVRKLGSGQFGEVWMGYYK---NNMK--VAIKTLKE--GTMSPEAFLGEANMM 288
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGM 945
+++H L++L AV + ++T+ M GCL+D+++T + ++ ++ QIA GM
Sbjct: 289 KALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM 348
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALE 1004
AY+E +HRDL A N+LV KI DFGLA+++D EY A G K PIKW A E
Sbjct: 349 AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIID---SEYTAQEGAKFPIKWTAPE 405
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
I +FT K+DVW+FGV + E+++YG PY +S V +E G ++P+P C ++Y
Sbjct: 406 AIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELY 465
Query: 1065 -CVMVSCWMLDADSRPTFKQL 1084
V+ CW + RPTF+ L
Sbjct: 466 RGVIAECWRSRPEERPTFEFL 486
>BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for
IMAGE:4574968) protein.
Length = 599
Score = 184 bits (448), Expect = 2e-45
Identities = 101/258 (39%), Positives = 149/258 (57%), Gaps = 13/258 (5%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ LR LG G FG+V+ G + N+K VAIK LKE G + + FL EA +M
Sbjct: 236 IPRQSLRLVRKLGSGQFGEVWMGYYK---NNMK--VAIKTLKE--GTMSPEAFLGEANVM 288
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGM 945
+++H L++L AV + ++T+ M GCL+D+++T + ++ ++ QIA GM
Sbjct: 289 KALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM 348
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALE 1004
AY+E +HRDL A N+LV KI DFGLA+++D EY A G K PIKW A E
Sbjct: 349 AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIID---SEYTAQEGAKFPIKWTAPE 405
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
I +FT K+DVW+FGV + E+++YG PY +S V +E G ++P+P C ++Y
Sbjct: 406 AIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELY 465
Query: 1065 -CVMVSCWMLDADSRPTF 1081
V+ CW + RPTF
Sbjct: 466 RGVIAECWRSRPEERPTF 483
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 183 bits (446), Expect = 3e-45
Identities = 102/259 (39%), Positives = 145/259 (55%), Gaps = 17/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K +D GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDT-----GKLPVKWTAPEALR 359
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 360 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 419
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 420 KNCWHLDAAMRPSFLQLRE 438
>S76617-1|AAB33265.1| 505|Homo sapiens blk protein.
Length = 505
Score = 183 bits (445), Expect = 5e-45
Identities = 101/261 (38%), Positives = 150/261 (57%), Gaps = 13/261 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+ LR LG G FG+V+ G + N+K VAIK LKE G + + FL EA +M
Sbjct: 236 IPRQSLRLVRKLGSGQFGEVWMGYYK---NNMK--VAIKTLKE--GTMSPEAFLGEANVM 288
Query: 887 ASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGM 945
+++H L++L AV + ++T+ M GCL+D+++T + ++ ++ QIA GM
Sbjct: 289 KALQHERLVRLYAVVTKEPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIAEGM 348
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALE 1004
AY+E +HRDL A N+LV KI DFGLA+++D EY A G K PIKW A E
Sbjct: 349 AYIERMNSIHRDLRAANILVSEALCCKIADFGLARIID---SEYTAQEGAKFPIKWTAPE 405
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+FT K+DVW+FGV + E+++YG PY +S V +E G ++P+P C ++Y
Sbjct: 406 AYHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCPPELY 465
Query: 1065 -CVMVSCWMLDADSRPTFKQL 1084
V+ CW + RPTF+ L
Sbjct: 466 RGVIAECWRSRPEERPTFEFL 486
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 182 bits (444), Expect = 6e-45
Identities = 103/263 (39%), Positives = 151/263 (57%), Gaps = 16/263 (6%)
Query: 837 MLGFGAFGKVYKGVWVP---EGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPN 893
+LG GAFG+VY+G V G +I VA+K LK+ + EFL+EA++M+ HPN
Sbjct: 1950 LLGSGAFGEVYEGTAVDILGVGSG-EIKVAVKTLKKGSTDQEKIEFLKEAHLMSKFNHPN 2008
Query: 894 LLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFL------NWCTQIARGMA 946
+L+ L VC+ N+ +I +LM G L+ Y+R + L + C I++G
Sbjct: 2009 ILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDISKGCV 2068
Query: 947 YLEEKRLVHRDLAARNVLVQ-----TPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWL 1001
YLE +HRDLAARN LV +P VKI DFGLA+ + N+ K G +P++W+
Sbjct: 2069 YLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYKNDYYRKRGEGLLPVRWM 2128
Query: 1002 ALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTL 1061
A E + IFT +SDVW+FG+ IWEIL+ G +PY S +V ++ G +L P C
Sbjct: 2129 APESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPD 2188
Query: 1062 DIYCVMVSCWMLDADSRPTFKQL 1084
D++ +M CW + D RPTF ++
Sbjct: 2189 DLWNLMTQCWAQEPDQRPTFHRI 2211
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 182 bits (443), Expect = 8e-45
Identities = 98/249 (39%), Positives = 145/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 277 LGNGQFGEVWMGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 329
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 330 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 390 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKS 447
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 448 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 507
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 508 EERPTFEYL 516
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 182 bits (443), Expect = 8e-45
Identities = 98/249 (39%), Positives = 145/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 277 LGNGQFGEVWMGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 329
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 330 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 390 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKS 447
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 448 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 507
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 508 EERPTFEYL 516
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 182 bits (442), Expect = 1e-44
Identities = 95/260 (36%), Positives = 148/260 (56%), Gaps = 11/260 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+K E+ LG G FG V G W +G+ VA+K++KE G+ + EF +EA M
Sbjct: 412 LKREEITLLKELGSGQFGVVQLGKW--KGQ---YDVAVKMIKE--GSMSEDEFFQEAQTM 464
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L++ VC + ++T+ + GCL++Y+R+H + + L C + GM
Sbjct: 465 MKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGM 524
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
A+LE + +HRDLAARN LV VK++DFG+ + + +D+Y + G K P+KW A E
Sbjct: 525 AFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRY--VLDDQYVSSVGTKFPVKWSAPE 582
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ ++ KSDVWAFG+ +WE+ S G +PY+ V + G +L +P + + IY
Sbjct: 583 VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIY 642
Query: 1065 CVMVSCWMLDADSRPTFKQL 1084
+M SCW + RPTF+QL
Sbjct: 643 QIMYSCWHELPEKRPTFQQL 662
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 182 bits (442), Expect = 1e-44
Identities = 95/260 (36%), Positives = 148/260 (56%), Gaps = 11/260 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+K E+ LG G FG V G W +G+ VA+K++KE G+ + EF +EA M
Sbjct: 412 LKREEITLLKELGSGQFGVVQLGKW--KGQ---YDVAVKMIKE--GSMSEDEFFQEAQTM 464
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L++ VC + ++T+ + GCL++Y+R+H + + L C + GM
Sbjct: 465 MKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGM 524
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
A+LE + +HRDLAARN LV VK++DFG+ + + +D+Y + G K P+KW A E
Sbjct: 525 AFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRY--VLDDQYVSSVGTKFPVKWSAPE 582
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ ++ KSDVWAFG+ +WE+ S G +PY+ V + G +L +P + + IY
Sbjct: 583 VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIY 642
Query: 1065 CVMVSCWMLDADSRPTFKQL 1084
+M SCW + RPTF+QL
Sbjct: 643 QIMYSCWHELPEKRPTFQQL 662
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 182 bits (442), Expect = 1e-44
Identities = 95/260 (36%), Positives = 148/260 (56%), Gaps = 11/260 (4%)
Query: 827 VKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIM 886
+K E+ LG G FG V G W +G+ VA+K++KE G+ + EF +EA M
Sbjct: 434 LKREEITLLKELGSGQFGVVQLGKW--KGQ---YDVAVKMIKE--GSMSEDEFFQEAQTM 486
Query: 887 ASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGM 945
+ HP L++ VC + ++T+ + GCL++Y+R+H + + L C + GM
Sbjct: 487 MKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGM 546
Query: 946 AYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEY-KAAGGKMPIKWLALE 1004
A+LE + +HRDLAARN LV VK++DFG+ + + +D+Y + G K P+KW A E
Sbjct: 547 AFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRY--VLDDQYVSSVGTKFPVKWSAPE 604
Query: 1005 CIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIY 1064
+ ++ KSDVWAFG+ +WE+ S G +PY+ V + G +L +P + + IY
Sbjct: 605 VFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDTIY 664
Query: 1065 CVMVSCWMLDADSRPTFKQL 1084
+M SCW + RPTF+QL
Sbjct: 665 QIMYSCWHELPEKRPTFQQL 684
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 555 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 610
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 670
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 671 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTA 728
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 729 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 788
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 789 VFRLMEQCWAYEPGQRPSFSTI 810
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 555 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 610
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 670
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 671 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTA 728
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 729 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 788
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 789 VFRLMEQCWAYEPGQRPSFSTI 810
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 181 bits (440), Expect = 2e-44
Identities = 98/249 (39%), Positives = 145/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 277 LGNGQFGEVWMGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 329
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 330 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 389
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 390 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPERALYGRFTIKS 447
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 448 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 507
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 508 EERPTFEYL 516
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 555 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 610
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 611 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 670
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 671 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGLRQVPVKWTA 728
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 729 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 788
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 789 VFRLMEQCWAYEPGQRPSFSTI 810
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes variant
4 protein.
Length = 752
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 485 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 540
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 541 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 600
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 601 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTA 658
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 659 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 718
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 719 VFRLMEQCWAYEPGQRPSFSTI 740
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes variant
3 protein.
Length = 764
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 497 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 552
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 553 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 612
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 613 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTA 670
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 671 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 730
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 731 VFRLMEQCWAYEPGQRPSFSTI 752
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes variant
1 protein.
Length = 694
Score = 181 bits (440), Expect = 2e-44
Identities = 92/262 (35%), Positives = 150/262 (57%), Gaps = 9/262 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
++ +L G +G G FG+V+ G +N VA+K +ET + +FL+EA I
Sbjct: 427 VLNHEDLVLGEQIGRGNFGEVFSGRL--RADNTL--VAVKSCRETLPPDLKAKFLQEARI 482
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ HPN+++L+ VC Q + ++ +L+ G + ++RT ++ K L A G
Sbjct: 483 LKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAG 542
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGG--KMPIKWLA 1002
M YLE K +HRDLAARN LV N +KI+DFG+++ + + Y A+GG ++P+KW A
Sbjct: 543 MEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSR--EEADGVYAASGGSRQVPVKWTA 600
Query: 1003 LECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLD 1062
E + + ++ +SDVW+FG+ +WE S GA PY N+S + E +E G +LP P +C
Sbjct: 601 PEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDA 660
Query: 1063 IYCVMVSCWMLDADSRPTFKQL 1084
++ +M CW + RP+F +
Sbjct: 661 VFRLMEQCWAYEPGQRPSFSTI 682
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 180 bits (439), Expect = 2e-44
Identities = 101/259 (38%), Positives = 144/259 (55%), Gaps = 18/259 (6%)
Query: 831 ELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVE 890
EL+ +G G FG V G + G V A+K +K T++ FL EA +M +
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY--RGNKV----AVKCIKNDA---TAQAFLAEASVMTQLR 244
Query: 891 HPNLLQLLAVCMTNQ--MMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAY 947
H NL+QLL V + + + ++T+ M G LVDY+R+ + +G L + + M Y
Sbjct: 245 HSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEY 304
Query: 948 LEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQ 1007
LE VHRDLAARNVLV N K++DFGL K + GK+P+KW A E ++
Sbjct: 305 LEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASTQDT------GKLPVKWTAPEALR 358
Query: 1008 HRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVM 1067
+ F+ KSDVW+FG+ +WEI S+G PY I ++V +E G K+ P C +Y VM
Sbjct: 359 EKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVM 418
Query: 1068 VSCWMLDADSRPTFKQLAD 1086
+CW LDA RP+F QL +
Sbjct: 419 KNCWHLDAAMRPSFLQLRE 437
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 180 bits (438), Expect = 3e-44
Identities = 104/270 (38%), Positives = 145/270 (53%), Gaps = 12/270 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V+ G W N VA+K LK G + K FLEEA +M + H L+QL
Sbjct: 269 LGTGCFGDVWLGTW-----NGSTKVAVKTLKP--GTMSPKAFLEEAQVMKLLRHDKLVQL 321
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 322 YAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHR 381
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV + KI DFGLA+L I +DEY G K PIKW A E FT KS
Sbjct: 382 DLRAANILVGERLACKIADFGLARL--IKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKS 439
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G +P P C +Y M W LD
Sbjct: 440 DVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDP 499
Query: 1076 DSRPTFKQLADTFAEMARDPGRYLVIPGDK 1105
+ RPTF+ L +F E PGD+
Sbjct: 500 EERPTFEYL-QSFLEDYFTSAEPQYQPGDQ 528
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 180 bits (438), Expect = 3e-44
Identities = 104/270 (38%), Positives = 145/270 (53%), Gaps = 12/270 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V+ G W N VA+K LK G + K FLEEA +M + H L+QL
Sbjct: 269 LGTGCFGDVWLGTW-----NGSTKVAVKTLKP--GTMSPKAFLEEAQVMKLLRHDKLVQL 321
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 322 YAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHR 381
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV + KI DFGLA+L I +DEY G K PIKW A E FT KS
Sbjct: 382 DLRAANILVGERLACKIADFGLARL--IKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKS 439
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G +P P C +Y M W LD
Sbjct: 440 DVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDP 499
Query: 1076 DSRPTFKQLADTFAEMARDPGRYLVIPGDK 1105
+ RPTF+ L +F E PGD+
Sbjct: 500 EERPTFEYL-QSFLEDYFTSAEPQYQPGDQ 528
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 180 bits (438), Expect = 3e-44
Identities = 104/270 (38%), Positives = 145/270 (53%), Gaps = 12/270 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG V+ G W N VA+K LK G + K FLEEA +M + H L+QL
Sbjct: 269 LGTGCFGDVWLGTW-----NGSTKVAVKTLKP--GTMSPKAFLEEAQVMKLLRHDKLVQL 321
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 322 YAVVSEEPIYIVTEFMCHGSLLDFLKNPEGQDLRLPQLVDMAAQVAEGMAYMERMNYIHR 381
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV + KI DFGLA+L I +DEY G K PIKW A E FT KS
Sbjct: 382 DLRAANILVGERLACKIADFGLARL--IKDDEYNPCQGSKFPIKWTAPEAALFGRFTIKS 439
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G +P P C +Y M W LD
Sbjct: 440 DVWSFGILLTELITKGRIPYPGMNKREVLEQVEQGYHMPCPPGCPASLYEAMEQTWRLDP 499
Query: 1076 DSRPTFKQLADTFAEMARDPGRYLVIPGDK 1105
+ RPTF+ L +F E PGD+
Sbjct: 500 EERPTFEYL-QSFLEDYFTSAEPQYQPGDQ 528
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 180 bits (437), Expect = 4e-44
Identities = 97/249 (38%), Positives = 144/249 (57%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G F +V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 225 LGQGCFAEVWLGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 277
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 278 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 337
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 338 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKS 395
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 396 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 455
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 456 EERPTFEYL 464
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 180 bits (437), Expect = 4e-44
Identities = 97/249 (38%), Positives = 144/249 (57%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G F +V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 274 LGQGCFAEVWLGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 326
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 327 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 387 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPEAALYGRFTIKS 444
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 445 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 504
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 505 EERPTFEYL 513
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 180 bits (437), Expect = 4e-44
Identities = 106/281 (37%), Positives = 156/281 (55%), Gaps = 13/281 (4%)
Query: 806 CEDNEPLRPTNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIK 865
C+ +P +P KP V L+ LG G FG+V+ G + N VA+K
Sbjct: 224 CQTQKPQKPQ--KPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYY-----NGHTKVAVK 276
Query: 866 VLKETTGANTSKEFLEEAYIMASVEHPNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH 925
LK+ G+ + FL EA +M ++H L++L AV + +IT+ M G LVD+++T
Sbjct: 277 SLKQ--GSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTP 334
Query: 926 KE-KIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDI 984
K+ L+ QIA GM ++EE+ +HRDL A N+LV S KI DFGLA+L++
Sbjct: 335 SGIKLTINKLLDMAAQIAEGMVFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIED 394
Query: 985 NEDEYKAA-GGKMPIKWLALECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNV 1043
NE Y A G K PIKW A E I + FT KSDVW+FG+ + EI+++G PY ++ V
Sbjct: 395 NE--YTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNLEV 452
Query: 1044 PELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQL 1084
+ +E G ++ +P C ++Y +M CW + RPTF L
Sbjct: 453 IQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYL 493
>L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase protein.
Length = 879
Score = 180 bits (437), Expect = 4e-44
Identities = 105/299 (35%), Positives = 160/299 (53%), Gaps = 32/299 (10%)
Query: 815 TNVKPNLAKLRIVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGAN 874
T P+ I +E + G +G G FG V++G+++ EN + VAIK K T +
Sbjct: 225 TYTMPSTRDYEIQRE-RIELGRCIGEGQFGDVHQGIYMSP-ENPALAVAIKTCKNCTSDS 282
Query: 875 TSKEFLEEAYIMAS--------VEHPNL---------------------LQLLAVCMTNQ 905
++FL+EA S + PN+ ++L+ V N
Sbjct: 283 VREKFLQEACHYTSLHWNWCRYISDPNVDACPDPRNAELTMRQFDHPHIVKLIGVITENP 342
Query: 906 MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARGMAYLEEKRLVHRDLAARNVLV 965
+ +I +L LG L +++ K + + + + Q++ +AYLE KR VHRD+AARNVLV
Sbjct: 343 VWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLV 402
Query: 966 QTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRIFTHKSDVWAFGVTIW 1025
+ + VK+ DFGL++ ++ + YKA+ GK+PIKW+A E I R FT SDVW FGV +W
Sbjct: 403 SSNDCVKLGDFGLSRYME-DSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMW 461
Query: 1026 EILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDADSRPTFKQL 1084
EIL +G +P++ + +V IENG +LP P C +Y +M CW D RP F +L
Sbjct: 462 EILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 520
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 179 bits (436), Expect = 6e-44
Identities = 100/249 (40%), Positives = 146/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK+ G+ + FL EA +M ++H L++L
Sbjct: 251 LGAGQFGEVWMGYY-----NGHTKVAVKSLKQ--GSMSPDAFLAEANLMKQLQHQRLVRL 303
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G LVD+++T K+ L+ QIA GMA++EE+ +HR
Sbjct: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV S KI DFGLA+L++ NE Y A G K PIKW A E I + FT KS
Sbjct: 364 DLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAINYGTFTIKS 421
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI+++G PY ++ V + +E G ++ +P C ++Y +M CW
Sbjct: 422 DVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 481
Query: 1076 DSRPTFKQL 1084
+ RPTF L
Sbjct: 482 EDRPTFDYL 490
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 179 bits (436), Expect = 6e-44
Identities = 100/249 (40%), Positives = 146/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK+ G+ + FL EA +M ++H L++L
Sbjct: 251 LGAGQFGEVWMGYY-----NGHTKVAVKSLKQ--GSMSPDAFLAEANLMKQLQHQRLVRL 303
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G LVD+++T K+ L+ QIA GMA++EE+ +HR
Sbjct: 304 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 363
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV S KI DFGLA+L++ NE Y A G K PIKW A E I + FT KS
Sbjct: 364 DLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAINYGTFTIKS 421
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI+++G PY ++ V + +E G ++ +P C ++Y +M CW
Sbjct: 422 DVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 481
Query: 1076 DSRPTFKQL 1084
+ RPTF L
Sbjct: 482 EDRPTFDYL 490
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 179 bits (436), Expect = 6e-44
Identities = 95/273 (34%), Positives = 148/273 (54%), Gaps = 16/273 (5%)
Query: 832 LRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEH 891
L G +G G FG V +G ++ + K +K T++ FL+E +M ++H
Sbjct: 194 LTLGAQIGEGEFGAVLQGEYLGQ----------KCVKNIKCDVTAQAFLDETAVMTKMQH 243
Query: 892 PNLLQLLAVCMTNQMMLITQLMPLGCLVDYVRTH-KEKIGSKAFLNWCTQIARGMAYLEE 950
NL++LL V + + ++ + + G LV+++RT + + + L + + GM YLE
Sbjct: 244 ENLVRLLGVILDQGLYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVREGMEYLES 303
Query: 951 KRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGKMPIKWLALECIQHRI 1010
K+LVHRDLAARN+LV K++DFGLAK D ++P+KW A E ++H
Sbjct: 304 KKLVHRDLAARNILVSEELVAKVSDFGLAKAERKGLDS-----SRLPVKWTAPEALKHGK 358
Query: 1011 FTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSC 1070
FT KSDVW+FGV +WE+ SYG PY +S + V E +E ++ P C ++ +M SC
Sbjct: 359 FTSKSDVWSFGVLLWEVFSYGRAPYPKMSLKEVSEAVEKRYRMEPPEGCPGPVHVLMSSC 418
Query: 1071 WMLDADSRPTFKQLADTFAEMARDPGRYLVIPG 1103
W + RP F++LA+ A R G + G
Sbjct: 419 WEAEPARRPPFRKLAEKLARELRSAGAPASVSG 451
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 496
Score = 179 bits (436), Expect = 6e-44
Identities = 100/249 (40%), Positives = 146/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK+ G+ + FL EA +M ++H L++L
Sbjct: 238 LGAGQFGEVWMGYY-----NGHTKVAVKSLKQ--GSMSPDAFLAEANLMKQLQHQRLVRL 290
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G LVD+++T K+ L+ QIA GMA++EE+ +HR
Sbjct: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV S KI DFGLA+L++ NE Y A G K PIKW A E I + FT KS
Sbjct: 351 DLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAINYGTFTIKS 408
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI+++G PY ++ V + +E G ++ +P C ++Y +M CW
Sbjct: 409 DVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 468
Query: 1076 DSRPTFKQL 1084
+ RPTF L
Sbjct: 469 EDRPTFDYL 477
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK protein.
Length = 496
Score = 179 bits (436), Expect = 6e-44
Identities = 100/249 (40%), Positives = 146/249 (58%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK+ G+ + FL EA +M ++H L++L
Sbjct: 238 LGAGQFGEVWMGYY-----NGHTKVAVKSLKQ--GSMSPDAFLAEANLMKQLQHQRLVRL 290
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G LVD+++T K+ L+ QIA GMA++EE+ +HR
Sbjct: 291 YAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHR 350
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV S KI DFGLA+L++ NE Y A G K PIKW A E I + FT KS
Sbjct: 351 DLRAANILVSDTLSCKIADFGLARLIEDNE--YTAREGAKFPIKWTAPEAINYGTFTIKS 408
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI+++G PY ++ V + +E G ++ +P C ++Y +M CW
Sbjct: 409 DVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERP 468
Query: 1076 DSRPTFKQL 1084
+ RPTF L
Sbjct: 469 EDRPTFDYL 477
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 179 bits (435), Expect = 8e-44
Identities = 94/261 (36%), Positives = 148/261 (56%), Gaps = 9/261 (3%)
Query: 826 IVKEAELRRGGMLGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYI 885
I+ ++ G +LG G FG+VYKG K VA+K KE +FL+EA I
Sbjct: 557 ILSHEDVILGELLGKGNFGEVYKGTLKD-----KTSVAVKTCKEDLPQELKIKFLQEAKI 611
Query: 886 MASVEHPNLLQLLAVCMTNQ-MMLITQLMPLGCLVDYVRTHKEKIGSKAFLNWCTQIARG 944
+ +HPN+++L+ VC Q + +I +L+ G + ++R K+++ K + + A G
Sbjct: 612 LKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAG 671
Query: 945 MAYLEEKRLVHRDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAAGGK-MPIKWLAL 1003
M YLE K +HRDLAARN LV N +KI+DFG+++ D Y ++G K +PIKW A
Sbjct: 672 MLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSRQED--GGVYSSSGLKQIPIKWTAP 729
Query: 1004 ECIQHRIFTHKSDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDI 1063
E + + ++ +SDVW+FG+ +WE S G PY ++ + E +E G ++ P C DI
Sbjct: 730 EALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDI 789
Query: 1064 YCVMVSCWMLDADSRPTFKQL 1084
+M+ CW ++RP F +L
Sbjct: 790 SKIMMKCWDYKPENRPKFSEL 810
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 178 bits (434), Expect = 1e-43
Identities = 97/249 (38%), Positives = 144/249 (57%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G F +V+ G W N VAIK LK G + + FLEEA IM ++H L+QL
Sbjct: 274 LGQGCFAEVWLGTW-----NGNTKVAIKTLKP--GTMSPESFLEEAQIMKKLKHDKLVQL 326
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHKEK-IGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + ++T+ M G L+D+++ + + + ++ Q+A GMAY+E +HR
Sbjct: 327 YAVVSEEPIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIERMNYIHR 386
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL + N+LV KI DFGLA+L++ NE Y A G K PIKW A E + FT KS
Sbjct: 387 DLRSANILVGNGLICKIADFGLARLIEDNE--YTARQGAKFPIKWTAPERALYGRFTIKS 444
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + E+++ G PY ++ R V E +E G ++P P C + ++ +M+ CW D
Sbjct: 445 DVWSFGILLTELVTKGRVPYPGMNNREVLEQVERGYRMPCPQDCPISLHELMIHCWKKDP 504
Query: 1076 DSRPTFKQL 1084
+ RPTF+ L
Sbjct: 505 EERPTFEYL 513
>X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein.
Length = 348
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 90 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 142
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 143 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 202
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 203 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 260
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 261 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 320
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 321 EERPTFEYI 329
>M16592-1|AAA52644.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 247 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 299
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 300 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 359
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 360 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 417
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 418 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 477
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 478 EERPTFEYI 486
>M16591-1|AAA52643.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 247 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 299
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 300 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 359
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 360 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 417
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 418 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 477
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 478 EERPTFEYI 486
>BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 268 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 320
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 321 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 380
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 381 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 438
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 439 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 498
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 499 EERPTFEYI 507
>BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 268 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 320
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 321 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 380
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 381 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 438
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 439 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 498
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 499 EERPTFEYI 507
>BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 268 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 320
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 321 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 380
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 381 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 438
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 439 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 498
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 499 EERPTFEYI 507
>BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 268 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 320
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 321 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 380
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 381 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 438
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 439 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 498
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 499 EERPTFEYI 507
>BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 268 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 320
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 321 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 380
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 381 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 438
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 439 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 498
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 499 EERPTFEYI 507
>AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 247 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 299
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 300 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 359
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 360 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 417
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 418 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 477
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 478 EERPTFEYI 486
>AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 246 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 298
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 299 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 358
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 359 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 416
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 417 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 476
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 477 EERPTFEYI 485
>AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 246 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 298
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 299 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 358
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 359 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 416
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 417 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 476
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 477 EERPTFEYI 485
>AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 247 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 299
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 300 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 359
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 360 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 417
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 418 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 477
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 478 EERPTFEYI 486
>AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens cDNA:
FLJ22779 fis, clone KAIA1741. ).
Length = 505
Score = 177 bits (432), Expect = 2e-43
Identities = 94/249 (37%), Positives = 147/249 (59%), Gaps = 11/249 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ + N VA+K +K G+ + + FL EA +M +++H L++L
Sbjct: 247 LGAGQFGEVWMATY-----NKHTKVAVKTMKP--GSMSVEAFLAEANVMKTLQHDKLVKL 299
Query: 898 LAVCMTNQMMLITQLMPLGCLVDYVRTHK-EKIGSKAFLNWCTQIARGMAYLEEKRLVHR 956
AV + +IT+ M G L+D++++ + K +++ QIA GMA++E++ +HR
Sbjct: 300 HAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHR 359
Query: 957 DLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHKS 1015
DL A N+LV KI DFGLA++++ NE Y A G K PIKW A E I FT KS
Sbjct: 360 DLRAANILVSASLVCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGSFTIKS 417
Query: 1016 DVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLDA 1075
DVW+FG+ + EI++YG PY +S V +E G ++P+P C ++Y +M+ CW
Sbjct: 418 DVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRP 477
Query: 1076 DSRPTFKQL 1084
+ RPTF+ +
Sbjct: 478 EERPTFEYI 486
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 177 bits (431), Expect = 2e-43
Identities = 99/250 (39%), Positives = 147/250 (58%), Gaps = 12/250 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK G + + FLEEA +M +++H L++L
Sbjct: 232 LGAGQFGEVWMGYY-----NNSTKVAVKTLKP--GTMSVQAFLEEANLMKTLQHDKLVRL 284
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AV + + +IT+ M G L+D++++ + K+ +++ QIA GMAY+E K +H
Sbjct: 285 YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH 344
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHK 1014
RDL A NVLV KI DFGLA++++ NE Y A G K PIKW A E I FT K
Sbjct: 345 RDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGCFTIK 402
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVW+FG+ ++EI++YG PY + +V + G ++P+ C ++Y +M CW
Sbjct: 403 SDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEK 462
Query: 1075 ADSRPTFKQL 1084
A+ RPTF L
Sbjct: 463 AEERPTFDYL 472
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 177 bits (431), Expect = 2e-43
Identities = 99/250 (39%), Positives = 147/250 (58%), Gaps = 12/250 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK G + + FLEEA +M +++H L++L
Sbjct: 253 LGAGQFGEVWMGYY-----NNSTKVAVKTLKP--GTMSVQAFLEEANLMKTLQHDKLVRL 305
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AV + + +IT+ M G L+D++++ + K+ +++ QIA GMAY+E K +H
Sbjct: 306 YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH 365
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHK 1014
RDL A NVLV KI DFGLA++++ NE Y A G K PIKW A E I FT K
Sbjct: 366 RDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGCFTIK 423
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVW+FG+ ++EI++YG PY + +V + G ++P+ C ++Y +M CW
Sbjct: 424 SDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEK 483
Query: 1075 ADSRPTFKQL 1084
A+ RPTF L
Sbjct: 484 AEERPTFDYL 493
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 177 bits (431), Expect = 2e-43
Identities = 99/250 (39%), Positives = 147/250 (58%), Gaps = 12/250 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK G + + FLEEA +M +++H L++L
Sbjct: 253 LGAGQFGEVWMGYY-----NNSTKVAVKTLKP--GTMSVQAFLEEANLMKTLQHDKLVRL 305
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AV + + +IT+ M G L+D++++ + K+ +++ QIA GMAY+E K +H
Sbjct: 306 YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH 365
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHK 1014
RDL A NVLV KI DFGLA++++ NE Y A G K PIKW A E I FT K
Sbjct: 366 RDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGCFTIK 423
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVW+FG+ ++EI++YG PY + +V + G ++P+ C ++Y +M CW
Sbjct: 424 SDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEK 483
Query: 1075 ADSRPTFKQL 1084
A+ RPTF L
Sbjct: 484 AEERPTFDYL 493
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 177 bits (431), Expect = 2e-43
Identities = 99/250 (39%), Positives = 147/250 (58%), Gaps = 12/250 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK G + + FLEEA +M +++H L++L
Sbjct: 253 LGAGQFGEVWMGYY-----NNSTKVAVKTLKP--GTMSVQAFLEEANLMKTLQHDKLVRL 305
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AV + + +IT+ M G L+D++++ + K+ +++ QIA GMAY+E K +H
Sbjct: 306 YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH 365
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHK 1014
RDL A NVLV KI DFGLA++++ NE Y A G K PIKW A E I FT K
Sbjct: 366 RDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGCFTIK 423
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVW+FG+ ++EI++YG PY + +V + G ++P+ C ++Y +M CW
Sbjct: 424 SDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEK 483
Query: 1075 ADSRPTFKQL 1084
A+ RPTF L
Sbjct: 484 AEERPTFDYL 493
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 177 bits (431), Expect = 2e-43
Identities = 99/250 (39%), Positives = 147/250 (58%), Gaps = 12/250 (4%)
Query: 838 LGFGAFGKVYKGVWVPEGENVKIPVAIKVLKETTGANTSKEFLEEAYIMASVEHPNLLQL 897
LG G FG+V+ G + N VA+K LK G + + FLEEA +M +++H L++L
Sbjct: 253 LGAGQFGEVWMGYY-----NNSTKVAVKTLKP--GTMSVQAFLEEANLMKTLQHDKLVRL 305
Query: 898 LAVCMTNQ-MMLITQLMPLGCLVDYVRTHKE-KIGSKAFLNWCTQIARGMAYLEEKRLVH 955
AV + + +IT+ M G L+D++++ + K+ +++ QIA GMAY+E K +H
Sbjct: 306 YAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIERKNYIH 365
Query: 956 RDLAARNVLVQTPNSVKITDFGLAKLLDINEDEYKAA-GGKMPIKWLALECIQHRIFTHK 1014
RDL A NVLV KI DFGLA++++ NE Y A G K PIKW A E I FT K
Sbjct: 366 RDLRAANVLVSESLMCKIADFGLARVIEDNE--YTAREGAKFPIKWTAPEAINFGCFTIK 423
Query: 1015 SDVWAFGVTIWEILSYGARPYENISARNVPELIENGLKLPQPSICTLDIYCVMVSCWMLD 1074
SDVW+FG+ ++EI++YG PY + +V + G ++P+ C ++Y +M CW
Sbjct: 424 SDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCWKEK 483
Query: 1075 ADSRPTFKQL 1084
A+ RPTF L
Sbjct: 484 AEERPTFDYL 493
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.424
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 222,965,624
Number of Sequences: 224733
Number of extensions: 10445975
Number of successful extensions: 30006
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1931
Number of HSP's successfully gapped in prelim test: 877
Number of HSP's that attempted gapping in prelim test: 21913
Number of HSP's gapped (non-prelim): 5124
length of query: 1397
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1298
effective length of database: 50,986,271
effective search space: 66180179758
effective search space used: 66180179758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
- SilkBase 1999-2023 -