BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000601-TA|BGIBMGA000601-PA|IPR011009|Protein kinase-like, IPR000719|Protein kinase, IPR008271|Serine/threonine protein kinase, active site, IPR000472|TGF-beta receptor/activin receptor, type I/II, IPR003605|TGF beta receptor, GS motif, IPR002290|Serine/threonine protein kinase, IPR000333|Activin type II receptor (477 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 69 1e-12 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 69 1e-12 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 63 9e-11 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 62 1e-10 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 62 2e-10 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 61 3e-10 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 60 5e-10 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 60 7e-10 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 60 9e-10 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 60 9e-10 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 59 2e-09 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 59 2e-09 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 57 6e-09 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 57 6e-09 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 56 1e-08 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 55 2e-08 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 55 3e-08 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 54 3e-08 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 54 6e-08 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 54 6e-08 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 53 8e-08 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 52 2e-07 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 52 2e-07 SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 52 2e-07 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 52 2e-07 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 51 3e-07 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 51 3e-07 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 51 4e-07 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 51 4e-07 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 49 1e-06 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 49 1e-06 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 48 2e-06 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 48 3e-06 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 48 3e-06 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 48 4e-06 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 47 5e-06 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 47 5e-06 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 47 7e-06 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 47 7e-06 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 46 9e-06 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 46 9e-06 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 46 1e-05 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 46 1e-05 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 46 1e-05 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 46 1e-05 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 45 2e-05 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 44 5e-05 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 43 8e-05 SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schiz... 43 8e-05 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 43 8e-05 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 43 1e-04 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 43 1e-04 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 42 1e-04 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 42 2e-04 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 42 2e-04 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 42 2e-04 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 41 3e-04 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 41 3e-04 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 40 6e-04 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 40 8e-04 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 40 0.001 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 39 0.001 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 39 0.002 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 38 0.002 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 38 0.004 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 37 0.005 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 36 0.009 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 36 0.016 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 35 0.022 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 35 0.029 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 33 0.066 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 33 0.087 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 33 0.087 SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces p... 33 0.12 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 32 0.15 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 31 0.35 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 31 0.35 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 31 0.47 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 30 0.62 SPAC1834.08 |mak1|phk3|histidine kinase Mak1|Schizosaccharomyces... 30 0.81 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 29 1.1 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 29 1.4 SPAPJ760.02c |app1||App1 protein|Schizosaccharomyces pombe|chr 1... 28 2.5 SPAC869.03c |||urea transporter |Schizosaccharomyces pombe|chr 1... 28 2.5 SPCC1902.01 |gaf1|SPCC417.01c|transcription factor Gaf1 |Schizos... 28 3.3 SPAC890.04c |||ribosome biogenesis protein Ytm1 |Schizosaccharom... 28 3.3 SPBC56F2.04 |utp20||U3 snoRNP protein Utp20|Schizosaccharomyces ... 27 4.3 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 27 4.3 SPAC23H3.06 |apl6||AP-3 adaptor complex subunit Apl6 |Schizosacc... 27 5.7 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 27 5.7 SPBC4B4.01c |||fumble family pantothenate kinase |Schizosaccharo... 27 7.6 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 27 7.6 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 69.3 bits (162), Expect = 1e-12 Identities = 60/205 (29%), Positives = 98/205 (47%), Gaps = 27/205 (13%) Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR---HENILGFIAADN 241 IG+G G+V+ R G N++V I +E + + ++++ H+NI+ FI Sbjct: 392 IGQGASGDVYSARQVGTNLSVAIKKMNINQQPKKEFIVNEILVMKSHHHKNIVNFI---- 447 Query: 242 KDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300 D + ++LW++ +Y GSL + +T ++ + + GL HLH + Sbjct: 448 -DTFFYKSELWMVMEYMRGGSLTEVVTNNTLSEGQIAAICKETLEGLQHLH--------E 498 Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360 I HRD+KS NIL+ + D G + DS T VGT +MAPEV+ Sbjct: 499 NGIVHRDIKSDNILLSLQGDIKLTDFGFCAQ----IDSNMTKRTTMVGTPYWMAPEVV-- 552 Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEM 385 TR+ +K DV+S G++ EM Sbjct: 553 ---TRKEYGFK-VDVWSLGIMAIEM 573 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 69.3 bits (162), Expect = 1e-12 Identities = 81/294 (27%), Positives = 126/294 (42%), Gaps = 51/294 (17%) Query: 176 ARQIQLVDIIGKGRFGEVWRGR--WRGENVAVKIFSS----REECSWFREAEIYQTVMLR 229 A I L D +GKG FG V+RG GE VAVK + + S + EI L Sbjct: 6 ASSITLGDCLGKGAFGAVYRGLNIKNGETVAVKKVKLSKMLKSDLSVIK-MEIDLLKNLD 64 Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNTLIKMSLSIATGLA 288 H NI+ + + ++ L +I +Y ENGSL I N + + + GL Sbjct: 65 HPNIVKYRGSYQTNDS----LCIILEYCENGSLRSICKNFGKIPENLVALYTFQVLQGLL 120 Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348 +LH + HRD+K NIL + + + D G+A + N D + VG Sbjct: 121 YLH--------NQGVIHRDIKGANILTTKDGTIKLADFGVATKINALEDH------SVVG 166 Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDP 408 + +MAPEV++ T SD++S G + E+ D PPYYD + P Sbjct: 167 SPYWMAPEVIELVGAT------TASDIWSVGCTVIELL--------DGNPPYYD-LDPTS 211 Query: 409 ALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKK 462 AL M + P +P+ + S + +C+ ++P R+ ++ K Sbjct: 212 ALFRM-----VKDEHPPLPSN-----ISSAAKSFLMQCFQKDPNLRIKTRKLLK 255 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 62.9 bits (146), Expect = 9e-11 Identities = 59/227 (25%), Positives = 108/227 (47%), Gaps = 32/227 (14%) Query: 182 VDIIGKGRFGEVWRG--RWRGENVAVKIFS---SREECSWFREAEIYQTVMLRHENILGF 236 ++++G+G +G V+RG E VA+KI + +E S ++ E+ L+ ++ Sbjct: 13 LELVGRGSYGAVYRGICNLTKETVAIKILNLDTDEDEVSDIQK-EVAVLSELKQSDVENI 71 Query: 237 IAADNKDNGTW---TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMD 293 I K +G++ T LW+I DY GS+ + A I + + L +H Sbjct: 72 I----KYHGSYLVGTNLWIIMDYCHGGSVRTLMEAGPISEPCISLILRETLQALKFIH-- 125 Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353 I HRD+K+ NILV + + + D G+A N++ +GT +M Sbjct: 126 ------HAGIIHRDIKAANILVSMSGNVKLCDFGVAAELNINRRK----RITFIGTPYWM 175 Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPY 400 APEV+ D ++++ +D++S G+ +E+A G+ P + P+ Sbjct: 176 APEVI---RDGQEYN--VMADIWSLGITAYEIA--TGSPPHAKEDPF 215 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 62.5 bits (145), Expect = 1e-10 Identities = 53/212 (25%), Positives = 102/212 (48%), Gaps = 22/212 (10%) Query: 178 QIQLVDIIGKGRFGEVW--RGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHEN--I 233 Q ++ ++IGKG + V+ + R + A+K + ++ + + ++L+ N + Sbjct: 29 QFKIRNVIGKGSWSTVFVVKHRQTKQRFALKCINKKKHDEHKIKKLRNEVLLLQSLNHPL 88 Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMD 293 L ++ +D T+++L+TD G L ++ + + + + + + + L ++H Sbjct: 89 LCKFYSEFEDE---TKIYLVTDLMLGGDLRYHISQRKFNESVIRIWMVELVSALIYIH-- 143 Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR-HNVSNDSVDVPSTNRVGTKRY 352 +KG + HRD+K NIL+ C + D +A + H S+ S + RVGT Y Sbjct: 144 ---SKG---VLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSPSKSNMTVGRVGTPVY 197 Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWE 384 MAPE L + YK SD +S G+ +E Sbjct: 198 MAPETLIHAVS------YKESDWWSLGITFYE 223 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 62.1 bits (144), Expect = 2e-10 Identities = 65/258 (25%), Positives = 107/258 (41%), Gaps = 28/258 (10%) Query: 139 DETKHILNTPTTTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFG------E 192 DE + L P I + ++ S ++ +S +++ +G G F E Sbjct: 128 DEIRIGLGVPKDEISFLCQVPVKHSRDSQKNMI-KSENSHYEIIRTLGSGTFAVVKLAVE 186 Query: 193 VWRGRWRGENVAVK----IFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWT 248 V G+W + K + SS + + + EI L H ++ D+ Sbjct: 187 VNSGKWYAIKIINKRKILLTSSEKRATEMFQREIDILKSLHHPGVVQCHEIFENDD---- 242 Query: 249 QLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRD 307 +L+++ +Y E G L DFL A SID + + L HLH K + HRD Sbjct: 243 ELFIVMEYVEGGDLMDFLIANGSIDEQDCKPLLKQLLETLLHLH--------KQGVTHRD 294 Query: 308 LKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQF 367 +K +NIL+ ++ I D GLA + + ++ GT Y+APEVL Sbjct: 295 IKPENILITNDFHLKISDFGLAKVIHGTGTFLE----TFCGTMGYLAPEVLKSKNVNLDG 350 Query: 368 DPYKRSDVYSFGLVLWEM 385 + D++S G VL+ M Sbjct: 351 GYDDKVDIWSLGCVLYVM 368 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 61.3 bits (142), Expect = 3e-10 Identities = 63/217 (29%), Positives = 107/217 (49%), Gaps = 34/217 (15%) Query: 184 IIGKGRFGEVWRGR--WRGENVAVK------IFSSREECSWFREA---EIYQTVMLRHEN 232 +IG G FG+V+ G GE +AVK + S++ + +A EI L HE+ Sbjct: 399 LIGSGSFGQVYLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELSHEH 458 Query: 233 ILGFIAAD-NKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLS-IATGLAHL 290 I+ ++ ++ N D+ L + +Y GS+ LT TL+K + GL +L Sbjct: 459 IVQYLGSNLNSDH-----LNIFLEYVPGGSVAGLLTMYGSFEETLVKNFIKQTLKGLEYL 513 Query: 291 HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPST--NRVG 348 H ++G I HRD+K NILV + I D G++ + +++ S + G Sbjct: 514 H-----SRG---IVHRDIKGANILVDNKGKIKISDFGISKKLELNSTSTKTGGARPSFQG 565 Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 + +MAPEV+ +TM T +++D++S G ++ EM Sbjct: 566 SSFWMAPEVVKQTMHT------EKTDIWSLGCLVIEM 596 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 60.5 bits (140), Expect = 5e-10 Identities = 50/153 (32%), Positives = 78/153 (50%), Gaps = 21/153 (13%) Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301 ++NG L++ +Y E SL D + K I + + ++ I LA++H ++G Sbjct: 716 QENGLNATLYIQMEYCEKLSLQDIIRDK-IPVDEMWRLFRQILEALAYIH-----SRG-- 767 Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAV---RHNVSND------SVDVPSTNRVGTKRY 352 + HRDLK NI + N + +GD GLA + +ND S D T VGT Y Sbjct: 768 -MMHRDLKPGNIFLDENRNVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALY 826 Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 +APE+L R +D + D+YS G++L+EM Sbjct: 827 VAPELLSRRNGVR-YD--AKVDMYSLGIILFEM 856 Score = 35.5 bits (78), Expect = 0.016 Identities = 39/179 (21%), Positives = 80/179 (44%), Gaps = 18/179 (10%) Query: 219 EAEIYQTVMLRHENILGFIA--ADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT 275 E E+ ++RH+ + + + G +L+++ +Y +LF L T ++D T Sbjct: 291 EYELESLKVIRHDLLASIYEYQLERETRGYGWRLYVLQEYSPKFTLFSLLQTVLTLDVET 350 Query: 276 LIKMSLSIATGLAHLHMDIVGTKG----KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR 331 + S +I GLA LH + K + H ++ L+ + + D+ + Sbjct: 351 VRAFSNNILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLRDMNASHP 410 Query: 332 HNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390 N+++ S+ TN + Y PEV + + +++D++ FGL++ +M CG Sbjct: 411 FNINSQSI----TNILPEGLY-PPEVSESSFAAAS----RKTDIWCFGLLVLQML--CG 458 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 60.1 bits (139), Expect = 7e-10 Identities = 58/211 (27%), Positives = 100/211 (47%), Gaps = 30/211 (14%) Query: 183 DIIGKGRFGEVWRGRWRGENV-AVKIFSSRE------ECSWFREAEIYQTVMLRHENILG 235 D IG+G F +R + N+ A K+ + R + F E +++Q+ + H NI+G Sbjct: 45 DCIGEGGFARCFRVKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQS--MSHPNIVG 102 Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDI 294 FI T ++LI + E+ SL + L K + + + + I L ++H Sbjct: 103 FIDCFEDS----TNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMH--- 155 Query: 295 VGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354 K + HRDLK NI++ + + IGD GLA + D + T GT Y+A Sbjct: 156 -----KKRVIHRDLKLGNIMLDESNNVKIGDFGLAA---LLMDDEERKMT-ICGTPNYIA 206 Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 PE+L + + F+ D++S G+V++ + Sbjct: 207 PEILFNSKEGHSFE----VDLWSAGVVMYAL 233 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 59.7 bits (138), Expect = 9e-10 Identities = 53/167 (31%), Positives = 83/167 (49%), Gaps = 24/167 (14%) Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLA 288 H+NI+ F + +N W W++ ++ + G LFD + ID + + G++ Sbjct: 71 HKNIIHFY--NTAENPQWR--WVVLEFAQGGDLFDKIEPDVGIDEDVAQFYFAQLMEGIS 126 Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348 +H +KG +AHRDLK +NIL+ N + I D G A + S + S VG Sbjct: 127 FMH-----SKG---VAHRDLKPENILLDYNGNLKISDFGFASLFSYKGKSRLLNSP--VG 176 Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395 + Y APE+ T+Q+D K DV+S G++L+ A GN P D Sbjct: 177 SPPYAAPEI------TQQYDGSK-VDVWSCGIILF--ALLLGNTPWD 214 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 59.7 bits (138), Expect = 9e-10 Identities = 55/210 (26%), Positives = 105/210 (50%), Gaps = 32/210 (15%) Query: 203 VAVKI-FSSREECSW---FREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHE 258 V +KI S+++ C RE I + + H +I+ ++ T ++ DY Sbjct: 526 VVIKIVLSTKQNCQTSRLMREVAILKGLGNNHPHIVKYLDFVK----TKHHFGIVLDYVN 581 Query: 259 NGSLFDFLTAKS-IDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKS 317 G LFD++ A+ ++ + ++ + +G+A+LH ++G + HRDLK +NIL+ + Sbjct: 582 GGELFDYILARRRLEDSVACRLFAQLISGVAYLH-----SRG---VVHRDLKLENILLDT 633 Query: 318 NLSCVIGDLGLAV---------RHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFD 368 N + VI D G A H++ + D+ ST+ G+ Y APE+++ + + Sbjct: 634 NRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTS-CGSPCYAAPELVN--CKSGMYA 690 Query: 369 PYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398 ++D++S G++L+ M G +P D P Sbjct: 691 G-TQADIWSCGVILYAML--AGYLPFDDDP 717 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 58.8 bits (136), Expect = 2e-09 Identities = 56/210 (26%), Positives = 98/210 (46%), Gaps = 31/210 (14%) Query: 185 IGKGRFGEVWR-----GRWRGENVAVKIFSSREECSWFREAEIYQTVMLR---HENILGF 236 +G+G G V+ G+ G +V I S +C +E + + ++R H NI+ + Sbjct: 315 LGQGASGSVYLAKVVGGKQLGIFDSVAIKSIDLQCQTRKELILNEITVMRESIHPNIVTY 374 Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296 + + LW++ +Y GSL D + + + ++ L G+ HLH Sbjct: 375 LDSFLVRE---RHLWVVMEYMNAGSLTDIIEKSKLTEAQIARICLETCKGIQHLH----- 426 Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR-HNVSNDSVDVPSTNRVGTKRYMAP 355 I HRD+KS N+L+ ++ + I D G R N +N V + VGT +MAP Sbjct: 427 ---ARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLSNRTNKRVTM-----VGTPYWMAP 478 Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 EV+ +Q + + D++S G+++ EM Sbjct: 479 EVV------KQNEYGTKVDIWSLGIMIIEM 502 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 58.8 bits (136), Expect = 2e-09 Identities = 68/221 (30%), Positives = 102/221 (46%), Gaps = 35/221 (15%) Query: 184 IIGKGRFGEVWRGRWRGEN--VAVKIFSSREECSWFREAEIYQTVMLRHENIL------- 234 +IGKG FG+V+ R N A+K S + R+ E+ T L NIL Sbjct: 307 LIGKGTFGQVYLVRKNDTNRIYAMKKISKK---LIVRKKEVTHT--LGERNILVRTSLDE 361 Query: 235 -GFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLS-IATGLAHLHM 292 FI T + L+LITDY G LF L + K ++ + L HLH Sbjct: 362 SPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLH- 420 Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352 K I +RDLK +NIL+ ++ + D GL + +N S + + GT Y Sbjct: 421 -------KHDIIYRDLKPENILLDADGHIALCDFGL----SKANLSANATTNTFCGTTEY 469 Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393 +APEVL ++ + + K+ D +S G++++EM CG P Sbjct: 470 LAPEVL---LEDKGYT--KQVDFWSLGVLVFEMC--CGWSP 503 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 56.8 bits (131), Expect = 6e-09 Identities = 66/244 (27%), Positives = 111/244 (45%), Gaps = 29/244 (11%) Query: 149 TTTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRG--RWRGENVAVK 206 T+T R+ + SG P+ + +D IG+G +G+V++ G+ VA+K Sbjct: 248 TSTARESVPAPLPSPPSG-PIYTYTYPKPAYEKIDQIGEGTYGKVYKAINTVTGDLVALK 306 Query: 207 IFSSREECSWF-----REAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGS 261 +E F RE +I Q LRH+NI+ + + + + ++ D+ G Sbjct: 307 RIRLEQEKDGFPITTVREVKILQR--LRHKNIVRLLEIMVEKSSVY-MVFEYMDHDLTGV 363 Query: 262 LFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSC 321 L + + + +S I LA+LH +G + HRD+K NIL+ +N Sbjct: 364 LLN--SQLHFTPGNIKHLSKQIFEALAYLHH-----RG---VLHRDIKGSNILLNNNGDL 413 Query: 322 VIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLV 381 D GLA R N S+ S + TNRV T + PE+L + +D D++S G + Sbjct: 414 KFADFGLA-RFNTSSKSANY--TNRVITLWFRPPELL---LGETAYD--TAVDIWSAGCI 465 Query: 382 LWEM 385 + E+ Sbjct: 466 VMEL 469 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 56.8 bits (131), Expect = 6e-09 Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 23/217 (10%) Query: 180 QLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAA 239 ++ ++G+G FG+V+ N V + SS + + EI+ L H NI Sbjct: 32 RIESVVGEGSFGKVYLAAHLLTNTKVVLKSSCRKQAIILAREIHHHRRLLHPNITRLYEV 91 Query: 240 DNKDNGTWTQLWLITDYHENGSLFDFLT-AKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298 ++ +++L +Y NG L+D++ K +D T ++ + + +LH Sbjct: 92 VCTED----RIYLAMEYCPNGELYDWVAREKRLDEKTTCRIMWQLCCAIQYLH------- 140 Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVL 358 + HRDLK +NI + + +GD G + + S + R GT Y APE++ Sbjct: 141 -RQGCVHRDLKLENIFLDKAYNVKLGDFGFSRDSDCSRRTF---MNTRCGTVAYCAPELV 196 Query: 359 DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395 + D++S G++++ A G +P D Sbjct: 197 QGHKYIGEC-----VDIWSLGIIMY--ALLIGRLPFD 226 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 55.6 bits (128), Expect = 1e-08 Identities = 57/187 (30%), Positives = 86/187 (45%), Gaps = 35/187 (18%) Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLF------DFLTAKSIDSNTLIKMSLS 282 RH NI+ F+ + +DN +++ +Y G L+ DF AK+ + + L Sbjct: 66 RHRNIIHFVESF-EDN---VYYYVVLEYCPLGDLYECILNNDFPNAKN-QPEMIKNIFLQ 120 Query: 283 IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVK-----SNLSCVIGDLGLAVRHNVSND 337 I G+AHLH I HRDLK +N L+ S L I D GLA R +S D Sbjct: 121 IIDGVAHLHSH--------GIYHRDLKPENFLLSLSEDGSELVVKISDFGLACRDKISYD 172 Query: 338 SVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM--ARRCGNMPDD 395 G+ RYMAPE +E +D + P + +D+++ G+ L + AR P + Sbjct: 173 F-------GTGSDRYMAPEQFEE-VDGAGYSP-RAADIWALGICLLNLIFARNPFTYPHE 223 Query: 396 YQPPYYD 402 P + D Sbjct: 224 KDPIFAD 230 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 55.2 bits (127), Expect = 2e-08 Identities = 61/229 (26%), Positives = 100/229 (43%), Gaps = 20/229 (8%) Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFI 237 +I ++ +GKG +G V++ + V + + R +I + + H+ + +I Sbjct: 319 EIIKLEELGKGNYGVVYKALHQPTGVTMALKEIRLSLEEATFNQIIMELDILHKAVSPYI 378 Query: 238 AADNKDNGTWTQLWLITDYHENGSLFDFLTAKSI-DSNTLIKMSLSIATGLAHLHMDIVG 296 +++ +Y + GS+ D L A I D L + + ++ GL L Sbjct: 379 VDFYGAFFVEGSVFICMEYMDAGSM-DKLYAGGIKDEGVLARTAYAVVQGLKTL------ 431 Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPE 356 K + I HRD+K N+LV SN + D G VS + V S +G + YMAPE Sbjct: 432 -KEEHNIIHRDVKPTNVLVNSNGQVKLCDFG------VSGNLVASISKTNIGCQSYMAPE 484 Query: 357 VLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCV 404 + T Y ++DV+S GL + EMA G P Y P Y + Sbjct: 485 RIRVGGPTNGVLTYTVQADVWSLGLTILEMA--LGAYP--YPPESYTSI 529 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 54.8 bits (126), Expect = 3e-08 Identities = 59/209 (28%), Positives = 97/209 (46%), Gaps = 35/209 (16%) Query: 185 IGKGRFGEVWRGRWR--GENVAVK------IFSSREECSWFREAEIYQTVMLRHENILGF 236 +GKG+FG V+ + + G VA+K + S+ E RE EI LRH+NIL Sbjct: 95 LGKGKFGRVYLAKEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSN--LRHKNILRL 152 Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLT-AKSIDSNTLIKMSLSIATGLAHLHMDIV 295 + + +++LI ++ G L+ L AK K +A L++LH Sbjct: 153 YGHFHDEK----RIYLILEFAGRGELYQHLRRAKRFSEEVASKYIFQMANALSYLH---- 204 Query: 296 GTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAP 355 K + HRD+K +NIL+ + + D G +V H SN T GT Y+ P Sbjct: 205 ----KKHVIHRDIKPENILLGIDGEIKLSDFGWSV-HAPSN-----RRTTLCGTLDYLPP 254 Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWE 384 E+++ T ++ D++S G++ +E Sbjct: 255 EMVEGKEHT------EKVDLWSLGVLTYE 277 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 54.4 bits (125), Expect = 3e-08 Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 18/154 (11%) Query: 228 LRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGL 287 LRH NI+ + K + T Q+ Y LF F+T + +M + G+ Sbjct: 298 LRHPNIIKVLDIIYKRH-TILQIIEYVPY----DLFTFITKGHCSALKADQMFFQLLDGV 352 Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347 A++H +G IAHRD+K NI++ NL+ I D G A + +S + S V Sbjct: 353 AYMHS--LG------IAHRDIKLDNIMLDENLNVKIIDFGTAFVFHYPFESTTLMSDGVV 404 Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLV 381 G+K Y+APEVL + + +DP DV+S +V Sbjct: 405 GSKPYVAPEVLTQ----KPYDP-SAVDVWSCAIV 433 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 53.6 bits (123), Expect = 6e-08 Identities = 65/257 (25%), Positives = 113/257 (43%), Gaps = 40/257 (15%) Query: 143 HILNTPTTTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRG--RWRG 200 H+L+ RD I+L +S S +I + Q + G FG+V+ G G Sbjct: 1011 HVLDDSVFRNRDFIKLASSFS----------NITIRWQQGHFVRSGMFGDVYTGVNMETG 1060 Query: 201 ENVAVK---IFSSREECSWFREAEIYQTVM--LRHENILGFIAADNKDNGTWTQLWLITD 255 + +AVK + SR S + TV+ L H N++ + + ++++ + Sbjct: 1061 DLLAVKEIKLQDSRTFRSTVDQIHNEMTVLERLNHPNVVTYYGVEVHRE----KVYIFME 1116 Query: 256 YHENGSLFDFLTAKSIDSNTLIKMSL-SIATGLAHLHMDIVGTKGKPAIAHRDLKSKNIL 314 + + GSL D L I+ ++K+ + + GLA++H I HRD+K NIL Sbjct: 1117 FCQGGSLADLLAHGRIEDENVLKVYVVQLLEGLAYIHSQ--------HILHRDIKPANIL 1168 Query: 315 VKSNLSCVIGDLGLAV------RHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFD 368 + D G A+ V + + + GT YMAPE++ + T++ D Sbjct: 1169 LDHRGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQHLAGTPMYMAPEII---LGTKKGD 1225 Query: 369 PYKRSDVYSFGLVLWEM 385 + D++S G V+ EM Sbjct: 1226 -FGAMDIWSLGCVILEM 1241 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 53.6 bits (123), Expect = 6e-08 Identities = 68/219 (31%), Positives = 97/219 (44%), Gaps = 31/219 (14%) Query: 184 IIGKGRFGEVWRGRWRG-ENV-AVKIFSSREECSWFREAEIYQTVMLRHENILG------ 235 +IGKG FG+V+ R + E V A+K+ S + R E+ TV R + Sbjct: 271 LIGKGTFGQVYLVRKKDTERVYAMKVLSKKVIV---RRKEVAHTVGERDILVQTSAADSP 327 Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLS-IATGLAHLHMDI 294 FI A T L+L+TDY G LF L K ++ + L LH Sbjct: 328 FIVALRFSFQTPKDLYLVTDYMAGGELFWHLQKSVRFPEERAKFYIAELLLALQALH--- 384 Query: 295 VGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354 K I +RDLK +NIL+ + D GL + +N SV + GT Y+A Sbjct: 385 -----KRGIVYRDLKPENILLDVQGHIALCDFGL----SKANLSVGTTTRTFCGTTDYLA 435 Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393 PEV+ +D +D D +S G++L+EM CG P Sbjct: 436 PEVI---LDEAGYD--MMVDFWSLGVLLYEMT--CGWSP 467 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 53.2 bits (122), Expect = 8e-08 Identities = 58/214 (27%), Positives = 97/214 (45%), Gaps = 23/214 (10%) Query: 176 ARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFREAEIYQTVMLRHENI 233 A L+ +G G FG VW+ R G+ +A+K + E + ML + N Sbjct: 6 ANSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIE-QEVFMLSNCNS 64 Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMD 293 I +T LW++ ++ + GS+ L ++ + + + GL +LH Sbjct: 65 SNVIQYYGCFVDGYT-LWILMEHMDGGSVSGLLKMGRLNEQVISIILREVLYGLNYLH-- 121 Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352 G+ I HRD+K+ NIL+ S+ V + D G+A + +SN + VGT + Sbjct: 122 -----GQNKI-HRDIKAANILLSSSTGNVKLADFGVAAQ--LSNAA--SRRHTFVGTPFW 171 Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMA 386 MAPEV+ +T +D++S G+ EMA Sbjct: 172 MAPEVIQQT------SYGLAADIWSLGITAIEMA 199 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 52.0 bits (119), Expect = 2e-07 Identities = 67/252 (26%), Positives = 115/252 (45%), Gaps = 36/252 (14%) Query: 154 DMIELTTSGSGSG-LP--LLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIF 208 D++E +T +G+ LP + +R I I + + +G+G FG+V + VA+K Sbjct: 7 DLMENSTMRNGARVLPPEAISKRHIGPYI-IRETLGEGSFGKVKLATHYKTQQKVALKFI 65 Query: 209 S----SREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFD 264 S + + E EI +LRH +I+ T T + ++ +Y G LFD Sbjct: 66 SRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVIT----TPTDIVMVIEY-AGGELFD 120 Query: 265 FLTAKS-IDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVI 323 ++ K + + + I + + H + I HRDLK +N+L+ NL+ I Sbjct: 121 YIVEKKRMTEDEGRRFFQQIICAIEYCH--------RHKIVHRDLKPENLLLDDNLNVKI 172 Query: 324 GDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLW 383 D GL+ N+ D + ++ G+ Y APEV++ + DV+S G+VL+ Sbjct: 173 ADFGLS---NIMTDGNFLKTS--CGSPNYAAPEVINGKLYAG-----PEVDVWSCGIVLY 222 Query: 384 EMARRCGNMPDD 395 M G +P D Sbjct: 223 VML--VGRLPFD 232 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 51.6 bits (118), Expect = 2e-07 Identities = 44/175 (25%), Positives = 84/175 (48%), Gaps = 14/175 (8%) Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGR--WRGENVAVKIFSSREECSWFREAEIYQTV 226 LL+ + + ++ V IIG G +G V++ + G AVK ++ + + Sbjct: 8 LLLGQVLGDSLRFVSIIGAGAYGVVYKAEDIYDGTLYAVKALCKDGLNEKQKKLQARELA 67 Query: 227 MLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSI---DSNTLIKMSLSI 283 + + +I ++ T ++++ Y NG LF ++T K + +S+ + + L + Sbjct: 68 LHARVSSHPYIITLHRVLETEDAIYVVLQYCPNGDLFTYITEKKVYQGNSHLIKTVFLQL 127 Query: 284 ATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVSND 337 + + H H VG I HRDLK +NI+V ++++ V + D GLA S+D Sbjct: 128 ISAVEHCHS--VG------IYHRDLKPENIMVGNDVNTVYLADFGLATTEPYSSD 174 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 51.6 bits (118), Expect = 2e-07 Identities = 57/215 (26%), Positives = 103/215 (47%), Gaps = 29/215 (13%) Query: 178 QIQLVDIIGKGRFGEVWRGR--WRGENVAVKIF---SSREECSWFREAEIYQTVMLRHEN 232 Q + + +IG+G FG V+R + + VA+K+ +++++ + EI + L + Sbjct: 5 QYRDLQLIGQGSFGSVFRAQDVESSKIVALKVVDLDATKDQIETLTQ-EINFLIDLNSVH 63 Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI-KMSLSIATGLAHLH 291 I + A+ +LW+ +Y + GS D L S +I ++ + L +LH Sbjct: 64 ITKYYASFVDG----FRLWITMEYCDGGSCLDLLKLSGTFSERVIAEVMRQVLEALVYLH 119 Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351 +GK HRD+K+ NIL + + D G++ + D D + VGT Sbjct: 120 -----GQGK---MHRDIKAANILTMKDGLVKLADFGVSGQLESLRDKND----DFVGTPF 167 Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMA 386 +MAPEV+ +T YK +D++S G+ +E+A Sbjct: 168 WMAPEVVKQTGYN-----YK-ADIWSLGITAYELA 196 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 51.6 bits (118), Expect = 2e-07 Identities = 45/146 (30%), Positives = 69/146 (47%), Gaps = 23/146 (15%) Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309 L+ + NG L D++ N L + + A A L +D + + HRDLK Sbjct: 173 LYFVLSLARNGELLDYI-------NKLGRFNEICAQYYAALIVDSIDYMHGRGVIHRDLK 225 Query: 310 SKNILVKSNLSCVIGDLGLAVRHNVSNDS-------VDVP---STNRVGTKRYMAPEVLD 359 +NIL+ N+ I D G A N S+ S D P S + VGT RY++PEVL Sbjct: 226 PENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLS 285 Query: 360 ETMDTRQFDPYKRSDVYSFGLVLWEM 385 + + SD+++FG +L++M Sbjct: 286 DKI------AGTASDIWAFGCILFQM 305 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 51.2 bits (117), Expect = 3e-07 Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 33/239 (13%) Query: 220 AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIK- 278 AEI L H NI+ ++ + T T + + +Y GS+ L L++ Sbjct: 879 AEISMIADLDHLNIVQYLGFEK----TETDISIFLEYVSGGSIGRCLRNYGPFEEQLVRF 934 Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338 +S + GL++LH +KG I HRDLK+ N+L+ + C I D G++ +H+ N Sbjct: 935 VSRQVLYGLSYLH-----SKG---IIHRDLKADNLLIDFDGVCKISDFGIS-KHS-DNVY 984 Query: 339 VDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398 + + + G+ +MAPEV+ D + + + DV+S G V+ EM G P Sbjct: 985 DNDANLSMQGSIFWMAPEVIHN--DHQGYS--AKVDVWSLGCVVLEML--AGRRP----- 1033 Query: 399 PYYDCVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457 D A++ M + + TEK+ P +P+ S I + + C+ N R TA Sbjct: 1034 -----WSTDEAIQAMFK-LGTEKKAPPIPSELVSQVSPEAI-QFLNACFTVNADVRPTA 1085 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 51.2 bits (117), Expect = 3e-07 Identities = 62/228 (27%), Positives = 108/228 (47%), Gaps = 40/228 (17%) Query: 181 LVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWF-----REAEIYQTVMLRHENI 233 L++ +G+G FGEV++ + R G+ A+K E F RE +I +++ +HENI Sbjct: 38 LMEKLGEGTFGEVYKSQRRKDGKVYALKRILMHTEKEGFPITAIREIKILKSI--KHENI 95 Query: 234 LGF-----IAADNKDNGTWTQLWLITDY--HENGSLFDFLTAKSIDSNTLIKMSLSIATG 286 + + AD K + ++++T Y H+ L + + K + M A G Sbjct: 96 IPLSDMTVVRADKKHRRRGS-IYMVTPYMDHDLSGLLENPSVKFTEPQIKCYMKQLFA-G 153 Query: 287 LAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLA---VRHNVSNDSVDVPS 343 +LH + I HRDLK+ N+L+ ++ I D GLA + +N + +P Sbjct: 154 TKYLHDQL--------ILHRDLKAANLLIDNHGILKIADFGLARVITEESYANKNPGLPP 205 Query: 344 TNR------VGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 NR V T+ Y +PE+L + R++ D++S G ++ EM Sbjct: 206 PNRREYTGCVVTRWYRSPELL---LGERRYT--TAIDMWSVGCIMAEM 248 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 50.8 bits (116), Expect = 4e-07 Identities = 54/212 (25%), Positives = 95/212 (44%), Gaps = 25/212 (11%) Query: 183 DIIGKGRFGEVWRG--RWRGENVAVKIFSSRE--ECSWFREAEIYQTVMLRHENILGFIA 238 DIIG G F +V R + + A+K+ + + + + I + M+R G Sbjct: 58 DIIGDGSFSKVRRATDKKSWKEYAIKVLDKKYIVKENKVKYVNIERDSMMRLNGFPGISR 117 Query: 239 ADNKDNGTWTQLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDIVGT 297 + +L+ + + NG L ++ + +D N + + I + + ++H Sbjct: 118 LFHTFQDD-LKLYYVLELAPNGELLQYIKKYRFLDENCVRFYAAEILSSIEYMH------ 170 Query: 298 KGKPAIAHRDLKSKNILVKSNLSCVIGDLG----LAVRHNVSNDSVDVPSTNRVGTKRYM 353 I HRDLK +NIL N+ I D G L ++ S D PS + VGT Y+ Sbjct: 171 --SCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNSPDYTTFPS-SFVGTAEYV 227 Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 APE+L + + K SD+++F V+++M Sbjct: 228 APELLSRQVVS------KSSDLWAFACVVYQM 253 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 50.8 bits (116), Expect = 4e-07 Identities = 45/133 (33%), Positives = 64/133 (48%), Gaps = 28/133 (21%) Query: 262 LFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVK----- 316 LF + T + L I +G+ H+H K HRD+K +NILVK Sbjct: 113 LFKRRQGRLFTKETAFNILLQIISGIEHIH--------KHGFMHRDIKPENILVKRISPK 164 Query: 317 ---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRS 373 S S +GD GLA R +VS+D P T V T+ Y APE+L + Y S Sbjct: 165 PISSRYSIKLGDFGLA-RPSVSSD----PLTEYVSTRWYRAPELL------LRSGSYNHS 213 Query: 374 -DVYSFGLVLWEM 385 D+Y+FG +++E+ Sbjct: 214 VDLYAFGCIVFEI 226 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 49.2 bits (112), Expect = 1e-06 Identities = 54/218 (24%), Positives = 96/218 (44%), Gaps = 24/218 (11%) Query: 175 IARQIQLVDIIGKGRFGEVWRGRWR--GENVAVK-IFSSREECSWFREA-EIYQTVMLRH 230 + + +++++IG+G +G V + G VAVK I R EI RH Sbjct: 35 LPEEYEMINLIGQGAYGVVCAALHKPSGLKVAVKKIHPFNHPVFCLRTLREIKLLRHFRH 94 Query: 231 ENILGFIAADNKDNGTWTQL---WLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGL 287 ENI+ + D ++ +L +++ + E L+ + ++ + + + I L Sbjct: 95 ENIISIL--DILPPPSYQELEDVYIVQELMET-DLYRVIRSQPLSDDHCQYFTYQILRAL 151 Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347 +H + HRDLK N+L+ +N + D GLA R + T V Sbjct: 152 KAMH--------SAGVVHRDLKPSNLLLNANCDLKVADFGLA-RSTTAQGGNPGFMTEYV 202 Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 T+ Y APE++ + R++ K D++S G +L EM Sbjct: 203 ATRWYRAPEIM---LSFREYS--KAIDLWSTGCILAEM 235 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 49.2 bits (112), Expect = 1e-06 Identities = 59/228 (25%), Positives = 104/228 (45%), Gaps = 38/228 (16%) Query: 182 VDIIGKGRFGEVWRG--------RWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENI 233 V ++G G F EV++ ++ + + VK +E +E I Q + H++I Sbjct: 569 VTLLGSGEFSEVFQVEDPVEKTLKYAVKKLKVKFSGPKERNRLLQEVSI-QRALKGHDHI 627 Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS----IDSNTLIKMSLSIATGLAH 289 + + D+ ++G + L++ + ENGSL FL + +D + K+ + +A GL Sbjct: 628 VELM--DSWEHGGF--LYMQVELCENGSLDRFLEEQGQLSRLDEFRVWKILVEVALGLQF 683 Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349 +H H DLK N+++ + IGD G+A V R G Sbjct: 684 IH--------HKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPR------GMEREGD 729 Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQ 397 Y+APEVL + +D K +D++S G+ ++E A +PD+ Q Sbjct: 730 CEYIAPEVLANHL----YD--KPADIFSLGITVFEAAANI-VLPDNGQ 770 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 48.4 bits (110), Expect = 2e-06 Identities = 47/178 (26%), Positives = 81/178 (45%), Gaps = 25/178 (14%) Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLI 277 E E+ ++ H N+L I + QL+++ +Y G LFD + K S Sbjct: 56 EGELVLLRLIEHPNVLQLIDVISAQE----QLFVVVEYMPGGELFDCMLRKGSFTEQDTA 111 Query: 278 KMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSND 337 K I GL + H K I HRDLK +N+ + ++ S IG+ G+A ++ Sbjct: 112 KFLWQILCGLEYCH--------KLHICHRDLKPENLYLDAHGSIKIGEFGMA---SIQQP 160 Query: 338 SVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395 + ++ G+ Y +PE++ R +D SD++S G++ + A G +P D Sbjct: 161 GKLLQTS--CGSPHYASPEII----MGRSYDGC-ASDIWSCGIIFF--ALLTGKLPFD 209 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 48.0 bits (109), Expect = 3e-06 Identities = 46/147 (31%), Positives = 63/147 (42%), Gaps = 19/147 (12%) Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLI 277 E I + V H NIL + N L+LIT+ G LFD + AK S Sbjct: 77 EIAILKRVSYEHPNILHLVDFFETVNN----LYLITELATGGELFDRICAKGSFYEADAA 132 Query: 278 KMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKS---NLSCVIGDLGLAVRHNV 334 + + + + +LH + I HRDLK +N+L +S N +I D GL+ + Sbjct: 133 ALMRTTTSAVKYLHDN--------GIVHRDLKPENLLYRSKDPNSDLLIADFGLS---HF 181 Query: 335 SNDSVDVPSTNRVGTKRYMAPEVLDET 361 DS GT YMAPEV T Sbjct: 182 YEDSQYYMLMTACGTPEYMAPEVFRRT 208 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 48.0 bits (109), Expect = 3e-06 Identities = 49/186 (26%), Positives = 84/186 (45%), Gaps = 11/186 (5%) Query: 183 DIIGKGRFGE-VWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241 ++IG G G V+RG + VAVK RE + Q H NI+ + Sbjct: 658 EVIGYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASREITLLQQSD-NHPNIVRYYCKQK 716 Query: 242 KDNGTWTQLWL----ITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH-MDIVG 296 D + + L ++D E +D L KSID L+ + IA G++HLH +D+V Sbjct: 717 SDQFLYIVIELCKCNLSDLIEKPIAYDDLF-KSID---LVSLLYQIAFGVSHLHSLDLVH 772 Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPE 356 KP + + L K+ + +I D GL+ + + + S+ + G+ + +PE Sbjct: 773 RDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLRNTTFEAAGSYGWRSPE 832 Query: 357 VLDETM 362 +L ++ Sbjct: 833 ILSGSL 838 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 47.6 bits (108), Expect = 4e-06 Identities = 30/87 (34%), Positives = 49/87 (56%), Gaps = 12/87 (13%) Query: 300 KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLD 359 K ++ HRD+K NI + N S +GD GL + D+ V + + VGT YM+PE++ Sbjct: 144 KQSVLHRDIKPANIFLDENNSVKLGDFGL----SKLLDNTRVFTQSYVGTPYYMSPEII- 198 Query: 360 ETMDTRQFDPYK-RSDVYSFGLVLWEM 385 + PY +SDV++ G V++E+ Sbjct: 199 ------RSSPYSAKSDVWALGCVIFEI 219 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 47.2 bits (107), Expect = 5e-06 Identities = 52/226 (23%), Positives = 98/226 (43%), Gaps = 25/226 (11%) Query: 173 RSIARQIQLVDIIGKGRFGEVWRGR--WRGENVAVKIFSSREE--------CSWFREAEI 222 R +++ +G+G G+V GR E +A+KI E S +E Sbjct: 129 RKYINHYEIIKELGRGMHGKVKLGRDTVTRELLAIKIIPKTERRPKLGRANASSQKEKVR 188 Query: 223 YQTVMLR---HENILGFIAADNKDNGTWTQLWLITDYHENGSL-FDFLTAKSIDSNTLIK 278 + +L+ H N++ + D+ + T+++L+ +Y G + + + + + + Sbjct: 189 REIAILKKCVHPNVVRL--REVIDDPSSTKVYLVLEYMSGGEVPWTDCDSPVLSISEARQ 246 Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVS-ND 337 + GL +LH I HRD+K N+L+ S+ I D G++ N N+ Sbjct: 247 YFRDVVLGLEYLHYQ--------GIIHRDIKPANLLLNSSNCVKISDFGVSYIANAGLNE 298 Query: 338 SVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLW 383 DV VGT + APE+ +D + + DV++ G+ L+ Sbjct: 299 DNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLF 344 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 47.2 bits (107), Expect = 5e-06 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 22/139 (15%) Query: 249 QLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRD 307 +L+LI Y G LF L + + + + + + L HLH K I +RD Sbjct: 164 RLYLILQYAPGGELFSHLAEQRMLPEDVVAFYTAELTLALIHLH--------KLGIVYRD 215 Query: 308 LKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQF 367 LK +N L+ + ++ D GL+ V+ + D S VGT+ Y APE+L E Sbjct: 216 LKPENCLLDAEGHILLTDFGLS---KVAENGADCRSF--VGTEEYCAPEILLE------- 263 Query: 368 DPYKRS-DVYSFGLVLWEM 385 PY + D +S G++++++ Sbjct: 264 QPYDHAVDWWSMGILIFDL 282 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 46.8 bits (106), Expect = 7e-06 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 5/86 (5%) Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETM 362 +AHRDLK N++V SN I D G AV ++ V +T VG+ Y+AP ET+ Sbjct: 421 LAHRDLKLDNLVVDSNCFVKIIDFGSAVVFKYPFEADIVEATGVVGSDPYLAP----ETL 476 Query: 363 DTRQFDPYKRSDVYSFGLVLWEMARR 388 + +DP + D++S ++ MA R Sbjct: 477 VRKLYDP-RAVDIWSSAIIFCCMALR 501 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 46.8 bits (106), Expect = 7e-06 Identities = 58/228 (25%), Positives = 95/228 (41%), Gaps = 31/228 (13%) Query: 180 QLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFREAEIYQTVMLRHEN----- 232 Q V+ IG+G +G V++ R + G VA+K +E I + +L+ N Sbjct: 5 QKVEKIGEGTYGVVYKARHKLSGRIVAMKKIRLEDESEGVPSTAIREISLLKEVNDENNR 64 Query: 233 -----ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGL 287 +L + A++K + +L D + A S+D + K + + G+ Sbjct: 65 SNCVRLLDILHAESKLYLVFE--FLDMDLKKYMDRISETGATSLDPRLVQKFTYQLVNGV 122 Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347 H I HRDLK +N+L+ + + D GLA V + T+ + Sbjct: 123 NFCH--------SRRIIHRDLKPQNLLIDKEGNLKLADFGLARSFGVPLRNY----THEI 170 Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395 T Y APEVL + +R + D++S G + EM RR P D Sbjct: 171 VTLWYRAPEVL---LGSRHYS--TGVDIWSVGCIFAEMIRRSPLFPGD 213 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 46.4 bits (105), Expect = 9e-06 Identities = 46/196 (23%), Positives = 92/196 (46%), Gaps = 22/196 (11%) Query: 203 VAVKIFSSREECSWFREAEIYQTVMLR-HENILGFIAA-----DNKDNGTWTQLWLITDY 256 V +++S E F + EI +L+ + +++ +I + + T ++ L+ +Y Sbjct: 56 VLKRMYSPDENALRFVKTEIETMELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEY 115 Query: 257 HENGSLFDFLTAK---SIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNI 313 G L DF+ + + + ++K+ I G+A LH +P + HRDLK +N+ Sbjct: 116 CAGGGLIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHYL------RPPLIHRDLKVENV 169 Query: 314 LVKSNL--SCVIGDL--GLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDP 369 L+ N C G + + N S S N T +Y APE+++ D Sbjct: 170 LLSFNTFKLCDFGSVTEPMHAAENSSEIQALEKSINTFTTYQYRAPEMIN-LYSGLGID- 227 Query: 370 YKRSDVYSFGLVLWEM 385 ++SD+++ G++L+++ Sbjct: 228 -EKSDMWALGVLLYKL 242 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 46.4 bits (105), Expect = 9e-06 Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 15/160 (9%) Query: 227 MLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATG 286 +L HEN++ N D L ++ +Y G L S D L S Sbjct: 127 VLDHENVVKLYQVINSDYKD--SLCMVLNYCPGGKLASVDHGISFDPMPLETCRKSFRQL 184 Query: 287 LAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346 + L ++ + KG + HRD+K NIL K N + + D GLA + D P++ Sbjct: 185 V--LAVNYIHGKG---VIHRDIKPDNILFKENNNLCVIDFGLA--EFLPKDGFVKPAS-- 235 Query: 347 VGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMA 386 GT +MAPE+ D + + P D++S G+ L+ +A Sbjct: 236 -GTPAFMAPELFDNELKKIKGKPL---DIWSMGVTLYVIA 271 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 46.0 bits (104), Expect = 1e-05 Identities = 64/225 (28%), Positives = 100/225 (44%), Gaps = 36/225 (16%) Query: 185 IGKGRFGEVWR--GRWRGENVAVKI--FSSREECSWFR-EAEIYQTVMLRHENILGFIAA 239 IG G G+V GE A+K+ F+ R + E +LRH NI I Sbjct: 59 IGAGSMGKVKLVVNILTGEKAALKMIPFTPNNTSQTVRVQREALLGRLLRHPNICRVIDC 118 Query: 240 DNKDNGTWTQLWLITDYHENGSLFDFLTAKS-IDSNTLIKMSLSIATGLAHLHMDIVGTK 298 T+ ++ +Y G L +++ A+ +D + ++ + L +LH Sbjct: 119 IRTPACTY----ILFEYVPGGQLLEYILARGKLDEDLARSFAMQLINALVYLH------- 167 Query: 299 GKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357 K I HRDLK +N+L+ + V + D GL+ + S D D+ T G+ + APE+ Sbjct: 168 -KNFIVHRDLKIENVLLTQDSRQVKLIDFGLS--NFYSKD--DLLRT-YCGSLYFAAPEL 221 Query: 358 LDETMDTRQFDPY--KRSDVYSFGLVLWEMARRCGNMP-DDYQPP 399 LD PY DV+S G+V++ M CG +P DD P Sbjct: 222 LDA-------KPYIGPEVDVWSLGVVIYVMV--CGRVPFDDVSVP 257 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 46.0 bits (104), Expect = 1e-05 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 10/89 (11%) Query: 303 IAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE- 360 I H DLK N +LV+ NL + D G+A + ND+ ++ + +GT YMAPE L + Sbjct: 438 IVHSDLKPANFLLVEGNLKLI--DFGIAKA--IGNDTTNIHRDSHIGTINYMAPEALTDM 493 Query: 361 ----TMDTRQFDPYKRSDVYSFGLVLWEM 385 + + SDV+S G +L++M Sbjct: 494 NAHTNSGVKLVKLGRPSDVWSLGCILYQM 522 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 46.0 bits (104), Expect = 1e-05 Identities = 53/214 (24%), Positives = 97/214 (45%), Gaps = 28/214 (13%) Query: 180 QLVDIIGKGRFGEVWRGRWR--GENVAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235 Q ++ +G+G + V++G+ R GE VA+K+ + E EI LRH NI+ Sbjct: 4 QRLEKLGEGTYAHVYKGQNRVTGEIVALKVIRIDADEGTPSTAIREISLMKELRHPNIMS 63 Query: 236 FIAADNKDNGTWTQLWLITDYHENGS---LFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292 +N +L L+ +Y E + + ++ + + + + G++ H Sbjct: 64 LSDVLQTEN----KLMLVFEYMEKDLKKYMDTYGNQGALPPSQVKNFTQQLLKGISFCHE 119 Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352 + + HRDLK +N+L+ S + D GLA + ++ +N V T Y Sbjct: 120 N--------RVLHRDLKPQNLLINSRGELKLADFGLARSIGIPVNTF----SNEVVTLWY 167 Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMA 386 AP+VL + +R + D++S G ++ EMA Sbjct: 168 RAPDVL---LGSRVYS--TSIDIWSVGCIMAEMA 196 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 46.0 bits (104), Expect = 1e-05 Identities = 52/172 (30%), Positives = 76/172 (44%), Gaps = 34/172 (19%) Query: 221 EIYQTVMLRHENILGFIAADNKDNGTWTQ---LWLITDYHENGSLFDFLTAKSIDSNTLI 277 EI +LRH NIL WT ++L +Y +G LF ++ S Sbjct: 53 EILMMRLLRHPNILRLY-------DVWTDHQHMYLALEYVPDGELFHYIRKHGPLSEREA 105 Query: 278 KMSLS-IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVS 335 LS I +AH H + HRDLK +NIL+K N + I D G+A Sbjct: 106 AHYLSQILDAVAHCH--------RFRFRHRDLKLENILIKVNEQQIKIADFGMATVE--P 155 Query: 336 NDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYK--RSDVYSFGLVLWEM 385 NDS N G+ Y+APE++ PY+ +DV+S G++L+ + Sbjct: 156 NDSC---LENYCGSLHYLAPEIVSH-------KPYRGAPADVWSCGVILYSL 197 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 45.2 bits (102), Expect = 2e-05 Identities = 58/208 (27%), Positives = 92/208 (44%), Gaps = 33/208 (15%) Query: 185 IGKGRFGEVW--RGRWRGENVAVKI----FSSREECS-WFREAEIYQTVMLRHENILGFI 237 IG G FG V + + G NVAVK FS+ +RE ++ + LRHENI I Sbjct: 26 IGMGAFGLVCSAKDQLTGMNVAVKKIMKPFSTPVLAKRTYRELKLLKH--LRHENI---I 80 Query: 238 AADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGT 297 + + + ++ +T+ L LT++ +++ + I GL +H Sbjct: 81 SLSDIFISPFEDIYFVTELLGT-DLHRLLTSRPLETQFIQYFLYQILRGLKFVH------ 133 Query: 298 KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357 + HRDLK NIL+ N I D GLA D T V T+ Y APE+ Sbjct: 134 --SAGVIHRDLKPSNILINENCDLKICDFGLA-------RIQDPQMTGYVSTRYYRAPEI 184 Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEM 385 + + ++++ D++S G + EM Sbjct: 185 M---LTWQKYN--VEVDIWSAGCIFAEM 207 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 44.0 bits (99), Expect = 5e-05 Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 20/122 (16%) Query: 278 KMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSND 337 K++ + +GL++LH I HRD+K NIL+ S + D G VS + Sbjct: 185 KIAFGVLSGLSYLH--------DRKIIHRDIKPSNILLTSKGQVKLCDFG------VSGE 230 Query: 338 SVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQ 397 V+ + GT YMAPE + T SD++S GL L E+A P + Sbjct: 231 LVNSLAGTFTGTSYYMAPERISGGSYTIS------SDIWSLGLTLMEVALNRFPFPPEGS 284 Query: 398 PP 399 PP Sbjct: 285 PP 286 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 43.2 bits (97), Expect = 8e-05 Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 33/224 (14%) Query: 184 IIGKGRFGEVWRGRWR--GENVAVKIFSSREECS--WFREAEIYQTVMLRHENILGFIAA 239 ++G G F ++ G A KI ++ + +F + E+ L H NI+ Sbjct: 165 LLGIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRKLDHPNIIKV--- 221 Query: 240 DNKDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTK 298 N + + TQ ++ + G LF +LT ++ T + + I GL +LH Sbjct: 222 -NMEYNSETQFFIFEEMVTGGDLFSYLTKLGTVPEVTTLFIMFQILQGLKYLH------- 273 Query: 299 GKPAIAHRDLKSKNILVKSN----LSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354 + I HRDLK +NIL+ S+ ++ D G+A R + + VGT Y A Sbjct: 274 -EQNIIHRDLKLENILIASSSDTIFRIILTDFGVA-RCMQKGKRL----STFVGTPEYTA 327 Query: 355 PEVL----DETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMP 393 PE+ ++ Y K D++S G++++ + GN P Sbjct: 328 PEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLL--SGNSP 369 >SPAC23A1.06c |cmk2|mkp2|MAPK-activated protein kinase Cmk2|Schizosaccharomyces pombe|chr 1|||Manual Length = 504 Score = 43.2 bits (97), Expect = 8e-05 Identities = 40/144 (27%), Positives = 72/144 (50%), Gaps = 23/144 (15%) Query: 180 QLVDIIGKGRFGEVWRGRW--RGENVAVKIF-----SSREECSWFREAEIYQTVMLRHEN 232 QL++ +G G F +V++ R E+VAVK+ + ++ F+E I + V +H+N Sbjct: 66 QLIENLGDGAFSQVYKAYSIDRKEHVAVKVIRKYEMNKKQRQGVFKEVNIMRRV--KHKN 123 Query: 233 ILG-FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIK-MSLSIATGLAHL 290 ++ F + +D L+ + E G LF + + S L + + + +A + HL Sbjct: 124 VVNLFDFVETEDF-----YHLVMELAEGGELFHQIVNFTYFSENLARHIIIQVAEAVKHL 178 Query: 291 HMDIVGTKGKPAIAHRDLKSKNIL 314 H D+ G I HRD+K +N+L Sbjct: 179 H-DVCG------IVHRDIKPENLL 195 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 43.2 bits (97), Expect = 8e-05 Identities = 57/224 (25%), Positives = 103/224 (45%), Gaps = 35/224 (15%) Query: 180 QLVDIIGKGRFGEVWRGRWRGEN----VAVKIFS--SREECSWFREAEIYQTVM------ 227 +++ I G +G+V++ N A+K F S++ S ++ + Q+ + Sbjct: 6 KIIGFISSGTYGKVYKAVSSNSNDKRLFAIKKFKAESKQVSSNAQQTGVSQSAIREMMLC 65 Query: 228 --LRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLT---AKSIDSNTLIKMSLS 282 ++HENI+ + KD GT + ++ + H+ + F + + I + L + Sbjct: 66 REIQHENIVSLVQVLLKD-GTISMVFEYAE-HDLLQIIHFHSRSRTRQIPPSILKSILWQ 123 Query: 283 IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVP 342 I G+A+LH + I HRDLK NI++ + IGDLGL + + + Sbjct: 124 IINGVAYLHENW--------IMHRDLKPANIMITATGKVKIGDLGLG--RLIRDPILPFY 173 Query: 343 STNR-VGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 S++R V T Y APE+L + + P DV++ G + EM Sbjct: 174 SSDRVVVTIWYRAPELL---LGAHDYTP--AIDVWAIGCIYGEM 212 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 42.7 bits (96), Expect = 1e-04 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 25/155 (16%) Query: 246 TWTQLWLITDYHENGSLFDFLTAKS-IDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIA 304 T + +++ ++ + G + D++ + + K I + L++LH + ++ Sbjct: 212 TNSHYYMVFEFVDGGQMLDYIISHGKLKEKQARKFVRQIGSALSYLHQN--------SVV 263 Query: 305 HRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDT 364 HRDLK +NIL+ I D GL+ N+ + + G+ + APE+L+ Sbjct: 264 HRDLKIENILISKTGDIKIIDFGLS---NLYRRQSRLRTF--CGSLYFAAPELLNA---- 314 Query: 365 RQFDPY--KRSDVYSFGLVLWEMARRCGNMPDDYQ 397 PY DV+SFG+VL+ + CG +P D Q Sbjct: 315 ---QPYIGPEVDVWSFGIVLYVLV--CGKVPFDDQ 344 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 42.7 bits (96), Expect = 1e-04 Identities = 43/141 (30%), Positives = 65/141 (46%), Gaps = 24/141 (17%) Query: 250 LWLITDYHENGSLFDFLTAKSI----DSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAH 305 ++L DY ENG L FL+ + D + KM + L +H+ H Sbjct: 364 IFLQLDYCENGDLSLFLSELGLLQVMDPFRVWKMLFQLTQALNFIHL--------LEFVH 415 Query: 306 RDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTR 365 D+K N+L+ + + +GD GLA VS+ VD+ G + Y+APE+L Sbjct: 416 LDVKPSNVLITRDGNLKLGDFGLATSLPVSS-MVDLE-----GDRVYIAPEIL------A 463 Query: 366 QFDPYKRSDVYSFGLVLWEMA 386 + K +DVYS GL + E A Sbjct: 464 SHNYGKPADVYSLGLSMIEAA 484 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 42.3 bits (95), Expect = 1e-04 Identities = 49/234 (20%), Positives = 95/234 (40%), Gaps = 23/234 (9%) Query: 182 VDIIGKGRFGEVWRGRWRGEN--VAVKIFSSRE--ECSWFREAEIYQTVML-RHENILGF 236 + ++GKG FG+V + E A+K+ E + + V L + F Sbjct: 686 LSVLGKGNFGKVMLAELKSEKQLYAIKVLKKEFILENDEVESTKSEKRVFLVANRERHPF 745 Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296 + + T T+++ + D+ G L + + + + L + H + Sbjct: 746 LVNLHSCFQTETRIYFVMDFVSGGDLMLHIQQEQFSRRRAQFYAAEVCLALKYFHDN--- 802 Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPE 356 I +RDLK NIL+ + + D GL + ++ +D+ + GT +MAPE Sbjct: 803 -----GIIYRDLKLDNILLSPDGHVKVADYGLC-KEDMWHDNT---TATFCGTPEFMAPE 853 Query: 357 VLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPAL 410 +L E TR D ++FG+++++M + + +D + D L Sbjct: 854 ILLEQQYTRSV------DWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEPL 901 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 41.5 bits (93), Expect = 2e-04 Identities = 39/168 (23%), Positives = 85/168 (50%), Gaps = 23/168 (13%) Query: 230 HENILGFI---AADNKDNGTWTQLWLITDYHENGSLFDFLTAK---SIDSNTLIKMSLSI 283 H +I+ +I A +K + +++L+ ++ G L DF+ + + ++K+ + Sbjct: 111 HRHIVNYIDSSALYSKSENRY-EVYLLMEFCAGGGLIDFMNTRLQHRLTEGEILKILADV 169 Query: 284 ATGLAHLH-MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLA---VRHNVSNDSV 339 +A +H +D P + HRDLK +N+L+ + S + D G A + + D++ Sbjct: 170 CDAVAAMHYLD-------PPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTI 222 Query: 340 DVPSTNRVG--TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 N T +Y APE++D ++ RQ ++SD+++ G++ +++ Sbjct: 223 MFLEQNIAAYTTPQYRAPEMID--INRRQ-GIDEKSDIWAIGVLAYKL 267 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 41.5 bits (93), Expect = 2e-04 Identities = 42/141 (29%), Positives = 65/141 (46%), Gaps = 16/141 (11%) Query: 252 LITDYHENGSLFDFLTAKSIDSNTLIKMS--LSIATGLAHLHMDIVGTK--GKPAIAHRD 307 +I Y+ N ++ + D N +IK L+ A + ++ + G K + HRD Sbjct: 91 IINPYNFN-EVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIHSANVIHRD 149 Query: 308 LKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPS--TNRVGTKRYMAPEVLDETMDTR 365 LK N+LV ++ I D GLA S + + P T V T+ Y APE++ Sbjct: 150 LKPGNLLVNADCELKICDFGLA--RGCSENPEENPGFMTEYVATRWYRAPEIM------L 201 Query: 366 QFDPY-KRSDVYSFGLVLWEM 385 F Y K DV+S G +L E+ Sbjct: 202 SFSSYHKGIDVWSVGCILAEL 222 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 41.5 bits (93), Expect = 2e-04 Identities = 51/236 (21%), Positives = 99/236 (41%), Gaps = 31/236 (13%) Query: 184 IIGKGRFGEVWRGRWRGEN--VAVKIFSSR-----EECSWFR-EAEIYQTVML-RHENIL 234 ++GKG FG+V ++ A+K+ EE + E +++ +H +L Sbjct: 669 VLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKEKHPFLL 728 Query: 235 GFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI 294 A+ T T+++ + +Y G L + + + L + H + Sbjct: 729 NLFASFQ----TSTRVYFVMEYILGGDLMVHIQRQQFSVKRARFYGAEVCLALKYFHEN- 783 Query: 295 VGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354 IA+RDLK NIL+ + I D GL + + ++ ++ GT +MA Sbjct: 784 -------GIAYRDLKLDNILLCPDGHIRIADYGLCKENMLLGNT----TSTFCGTPEFMA 832 Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPAL 410 PE+L E +Q+ K D ++FG+++++M + + +D + D L Sbjct: 833 PEILLE----QQYS--KDVDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPL 882 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 41.1 bits (92), Expect = 3e-04 Identities = 39/138 (28%), Positives = 62/138 (44%), Gaps = 23/138 (16%) Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKM-SLSIATGLAHLHMDIVGTKGKPAIAHRDL 308 L+++ D+ E G LF L + K + + L +LH + I +RDL Sbjct: 274 LFMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHN--------QIVYRDL 325 Query: 309 KSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFD 368 K +N+L+ I D G A R + SN GT Y+APE++ Sbjct: 326 KPENLLLDRFGHLKIVDFGFAKRVSTSN------CCTLCGTPDYLAPEII-------SLK 372 Query: 369 PY-KRSDVYSFGLVLWEM 385 PY K +D +S G++++EM Sbjct: 373 PYNKAADWWSLGILIFEM 390 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 41.1 bits (92), Expect = 3e-04 Identities = 66/246 (26%), Positives = 106/246 (43%), Gaps = 38/246 (15%) Query: 174 SIARQIQLVDIIGKGRFGEVWRGRWRG---ENVAVKIFSSR--EECSWFREAEIYQTVML 228 SI +V +G G FG V+ + E VA+K + + R E++ + L Sbjct: 31 SIDEVYNVVRKVGDGTFGSVYLATTKTPSKEVVAIKSMKKKLAKVSDATRLREVHSLLRL 90 Query: 229 -RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMS---LSIA 284 +ENI+ + + L ++ ++ + +L+ ++ + D TL ++ I Sbjct: 91 SENENIVNIF---DLYIDQFRCLHIVMEFLDC-NLYQLISTRKNDPLTLEQVQDIMRQIF 146 Query: 285 TGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSN-----LSCVIGDLGLAVRHNVSNDSV 339 GL H+H T G HRD+K +NIL+ SN + I D GLA N Sbjct: 147 KGLNHIH-----TNG---FFHRDMKPENILISSNSDSSSFNVKIADFGLAREINSR---- 194 Query: 340 DVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP--DDYQ 397 P T V T+ Y APE+L D+ P D+Y+ G + +E+A P DD+ Sbjct: 195 -PPYTEYVSTRWYRAPELL--LRDSYYSFPV---DIYAAGCMAFEIATLQPIFPGNDDFD 248 Query: 398 PPYYDC 403 Y C Sbjct: 249 QLYKMC 254 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 40.3 bits (90), Expect = 6e-04 Identities = 42/171 (24%), Positives = 73/171 (42%), Gaps = 18/171 (10%) Query: 163 SGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFREA 220 SG G P + + +++ I KG FG V+ R GE A+K+ + S + A Sbjct: 554 SGKGTPSI------QDYEIIKPISKGTFGTVYLSRKNTTGEIYAIKVLRKVDMISKNQVA 607 Query: 221 EIY-QTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKM 279 + + +L + F+A + L+L+ ++ G L + + K+ Sbjct: 608 NVKAERAVLMAQEESAFVAKLYYAFQSRDYLYLVMEFMNGGDCASLLKSLYTIPESWAKI 667 Query: 280 SLS-IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLA 329 ++ +A GL HLH + I HRD+K NIL+ + D GL+ Sbjct: 668 YIAEVALGLEHLH--------RLGIIHRDIKPDNILMSITGHLKLADFGLS 710 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 39.9 bits (89), Expect = 8e-04 Identities = 69/281 (24%), Positives = 114/281 (40%), Gaps = 47/281 (16%) Query: 120 WAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELTTSGSGSGLPLLVQRSIARQI 179 W KK R + KR R +E+E N D L G+ P L + Sbjct: 25 WRKKRRLEKKRK-RKILEEEEKAEERNI------DACRLYLMGN---TPELKSCNSIDDY 74 Query: 180 QLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWF-----REAEIYQTVMLRHENIL 234 ++++ I +G +G V+RG + N V + + + + EI +RH+NI+ Sbjct: 75 EILEKIEEGSYGIVYRGLDKSTNTLVALKKIKFDPNGIGFPITSLREIESLSSIRHDNIV 134 Query: 235 GF----IAADNKDNGTWTQLWLITDY--HENGSLFDFLTAKSIDSNT-LIKMSLSIATGL 287 + D KD ++L+ ++ H+ +L D + + S + + L AT Sbjct: 135 ELEKVVVGKDLKD------VYLVMEFMEHDLKTLLDNMPEDFLQSEVKTLMLQLLAATAF 188 Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347 H H + HRDLK N+L+ + + D GLA + S+ T V Sbjct: 189 MHHHWYL----------HRDLKPSNLLMNNTGEIKLADFGLARPVSEPKSSL----TRLV 234 Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388 T Y APE+L + + K D++S G + EM R Sbjct: 235 VTLWYRAPELL---LGAPSYG--KEIDMWSIGCIFAEMITR 270 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 39.5 bits (88), Expect = 0.001 Identities = 47/159 (29%), Positives = 71/159 (44%), Gaps = 24/159 (15%) Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS-IDSNTLIKMSLSIATGL 287 R I+GF A N + L +Y + GSL L I + L K+ S+ GL Sbjct: 118 RSPYIVGFYGAFQYKNN----ISLCMEYMDCGSLDAILREGGPIPLDILGKIINSMVKGL 173 Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347 +L+ + I HRDLK N++V S + D G VS + V+ + V Sbjct: 174 IYLYNVL-------HIIHRDLKPSNVVVNSRGEIKLCDFG------VSGELVNSVAQTFV 220 Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMA 386 GT YM+PE + T +SD++S G+ + E+A Sbjct: 221 GTSTYMSPERIRGGKYT------VKSDIWSLGISIIELA 253 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 39.1 bits (87), Expect = 0.001 Identities = 55/208 (26%), Positives = 90/208 (43%), Gaps = 30/208 (14%) Query: 185 IGKGRFGEVWRGRW--RGENVAVKIFSSRE---ECSWFR-EAEIYQTVMLRHENILGFIA 238 +G+G +V G+ E VA+K+ + E + +W R + E+ L H NI+ Sbjct: 29 LGQGNLAKVKLGKHFQTNEKVALKMVYNDELEDKDTWKRLQREVTILRQLHHPNIITLYQ 88 Query: 239 ADNKDNGTWTQL-WLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGT 297 T L ++ TD H + +D T K+ I + + H+ Sbjct: 89 VFRVPKYTVLALEYMDTDLHSM-----VVKHNRLDECTTRKIFRQIVHAIDYCHLH---- 139 Query: 298 KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357 +AHRDLK +NIL+ +L + D GL+ N D + ++ GT Y APEV Sbjct: 140 ----RVAHRDLKLENILLNKDLVVKLTDFGLS---NFMLDGSFLSTS--CGTPHYAAPEV 190 Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEM 385 + R +D DV+ G++L+ M Sbjct: 191 I----QGRYYDGCD-VDVWGCGILLYLM 213 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 38.7 bits (86), Expect = 0.002 Identities = 56/222 (25%), Positives = 100/222 (45%), Gaps = 42/222 (18%) Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREEC-----SWFREAEIYQTVMLRHENILGFIAA 239 +G G +G+V ++ V I S + SW R+ ++ M +IL F+ A Sbjct: 509 LGIGAYGQVKLATYKSNKVHEVILKSISKSRILLDSWMRDKDLGTVPM--EISILHFLKA 566 Query: 240 DNKDNG----TWTQ----LWLITDYHENG-SLFDFLTAK-SIDSNTLIKMSLSIATGLAH 289 + N T+ + +L+T+ + G LFD++ K SI + IA +AH Sbjct: 567 HSHPNIVKMITFFEDNENYYLLTEPQKPGIDLFDYIELKPSISEKESKAIFFQIALAVAH 626 Query: 290 LH-MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348 LH DI+ HRD+K +N++++ N + D G S+ + + P G Sbjct: 627 LHSFDII---------HRDIKDENVILEGNGCARLIDFG------SSSLTKNGPFDTFRG 671 Query: 349 TKRYMAPEVLDETMDTRQFDPY--KRSDVYSFGLVLWEMARR 388 T + APE+L + + Y K D+++ G++L+ + R Sbjct: 672 TVGFAAPELL-------RGEKYLGKEQDIWALGILLYTIVYR 706 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 38.3 bits (85), Expect = 0.002 Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 16/96 (16%) Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSV-------DVPS----TNRVGT 349 P I++ D KN L K ++ IGD GL V + + ++ +P+ T +GT Sbjct: 437 PLISYND---KNDL-KEYITPKIGDFGLVVENKKNTETALSFLERNHLPNLQDETQHIGT 492 Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 Y APE+LD M ++ K+ D +S G+VL+E+ Sbjct: 493 ATYAAPELLD-AMSSQHNKFTKKIDTFSLGMVLFEL 527 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 37.5 bits (83), Expect = 0.004 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 7/88 (7%) Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETM 362 +AHRDLK +N+L+ + S I D G ++ + + G+ Y+APE E+ Sbjct: 477 VAHRDLKPENLLLTVSGSLKITDFGNGECFRMAWEKEAHMTCGLCGSAPYIAPEEYTES- 535 Query: 363 DTRQFDPYKRSDVYSFGLVLWEMARRCG 390 +FDP + DV++ G++ MA R G Sbjct: 536 ---EFDP-RAVDVWACGVIY--MAMRTG 557 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 37.1 bits (82), Expect = 0.005 Identities = 31/146 (21%), Positives = 69/146 (47%), Gaps = 19/146 (13%) Query: 249 QLWLITDYHENGSLFDFLTAK---SIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAH 305 ++ ++ +Y G L DFL + + ++K++ + +A +H KP + H Sbjct: 111 EVLVLLEYCPCGGLIDFLNTRLQVRLSEQEILKIASDVTEAVAVMHYL------KPPLIH 164 Query: 306 RDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPS------TNRVGTKRYMAPEVLD 359 RDLK +N+L+ + S + D G A H + + + T +Y PE+++ Sbjct: 165 RDLKIENVLLAAPNSYKLCDFGSAC-HPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMIN 223 Query: 360 ETMDTRQFDPYKRSDVYSFGLVLWEM 385 + F ++SD+++ G++ +++ Sbjct: 224 V---HKGFGIDEKSDIWALGVLFYKL 246 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 36.3 bits (80), Expect = 0.009 Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 3/59 (5%) Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSND--SVDVPSTNRVGTKRYMAPEVL 358 IAHRD+K +NIL+ I D G V N +D +V+ S G+ YMAPE+L Sbjct: 580 IAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKSMGIFGSDPYMAPEIL 638 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 35.5 bits (78), Expect = 0.016 Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 3/60 (5%) Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLA--VRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360 IAHRDLK +NIL+ + + D G + V + N+S+ S VG+ Y+APE E Sbjct: 252 IAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVS-GAVGSLAYLAPEAFHE 310 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 35.1 bits (77), Expect = 0.022 Identities = 54/235 (22%), Positives = 94/235 (40%), Gaps = 27/235 (11%) Query: 180 QLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILG---- 235 +L+ ++GKG FG+V + R R + + + ++ +E+ T L +L Sbjct: 231 ELLKVVGKGSFGKVMQVRKR-DTSRIYALKTMKKAHIVSRSEVDHT--LAERTVLAQVNN 287 Query: 236 -FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLS-IATGLAHLHMD 293 FI + +L+L+ + G LF L + K ++ + L LH Sbjct: 288 PFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLH-- 345 Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353 + + +RDLK +NIL+ + D GL + D + GT Y+ Sbjct: 346 ------EFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDR----TNTFCGTPEYL 395 Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDP 408 APE+L T K D ++ G++L+EM D+ Y + DP Sbjct: 396 APELLLGHGYT------KVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDP 444 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 34.7 bits (76), Expect = 0.029 Identities = 62/233 (26%), Positives = 95/233 (40%), Gaps = 31/233 (13%) Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRG--RWRGENVAVKIFSSREECSWFREAEIYQTVM 227 +V I + ++ IG G FG+++ G GE VAVK+ + + E Y+ Sbjct: 3 VVDIKIGNKYRIGRKIGSGSFGQIYLGLNTVNGEQVAVKLEPLKAR---HHQLE-YE--- 55 Query: 228 LRHENILGFIAADNKDN-GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI--KMSLSIA 284 R NIL K N G T W N + D L D K +L Sbjct: 56 FRVYNIL-------KGNIGIPTIRWFGVTNSYNAMVMDLLGPSLEDLFCYCGRKFTLKTV 108 Query: 285 TGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVSNDSVDVP- 342 LA + + + HRD+K N L+K + + V + D GLA ++ V +P Sbjct: 109 LLLADQLISRIEYVHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLAKKYRDFKTHVHIPY 168 Query: 343 --STNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393 + N GT RY + ++ + Q +R D+ S G VL R G++P Sbjct: 169 RDNKNLTGTARYAS---INTHIGIEQ---SRRDDLESLGYVLLYFCR--GSLP 213 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 33.5 bits (73), Expect = 0.066 Identities = 47/201 (23%), Positives = 90/201 (44%), Gaps = 24/201 (11%) Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243 ++G G FG V + + G + + ++ ++ E+ + H NI+ IA + Sbjct: 30 VLGSGSFGVVIQAKLVGTPGFIAVKRVLQD-KRYKNRELQIMRAISHPNIIKLIAFFHTH 88 Query: 244 NGTW--TQLWLITDYHENGSLFDFLT-----AKSIDSNTLIKMSLSIATGLAHLHMDIVG 296 N + T L L+ +Y ++FD + KSI + ++ + + LA+LH Sbjct: 89 NPSKDETHLCLLLEYMPE-TVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLH----- 142 Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCV-IGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAP 355 + HRD+K +N+LV + + D G A + V ++ P+ + + ++ Y AP Sbjct: 143 ---STGVCHRDIKPQNLLVDYKTGILKLCDFGSA-KVLVPSE----PNVSYICSRYYRAP 194 Query: 356 E-VLDETMDTRQFDPYKRSDV 375 E V T T + D + + V Sbjct: 195 ELVFGATHYTTKIDVWSAACV 215 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 33.1 bits (72), Expect = 0.087 Identities = 52/219 (23%), Positives = 98/219 (44%), Gaps = 39/219 (17%) Query: 180 QLVDIIGKGRFGEVWR--GRWRGENVAVKIFSSREECSWFREAEIYQTVMLRH------- 230 +++D +GKG FG+V + RG+ VA+K+ +R++ F + + +L+ Sbjct: 519 EIIDTVGKGSFGQVLKCIDHKRGQVVAIKVIKNRQK---FHGQTLVEVGILKRLCEADPA 575 Query: 231 --ENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288 N++ +++ + L ++T+ +LFD + + LI + GL Sbjct: 576 DKNNVIRYLSHFDFRG----HLCIVTEL-LGSNLFDVIRENNYKGLPLIVVKSFALQGLQ 630 Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIG--DLGLAVRHNVSNDSVDVPSTNR 346 L + +G+ I H DLK +N+L+ L I D G + + N+ V +R Sbjct: 631 ALRL----LQGQ-NIIHCDLKPENLLLSHPLKARIKLIDFGSSCFY---NEKVYTYLQSR 682 Query: 347 VGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 Y APE++ + K D++SFG +L E+ Sbjct: 683 F----YRAPEII------LGLEYGKEIDIWSFGCILAEL 711 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 33.1 bits (72), Expect = 0.087 Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 20/154 (12%) Query: 184 IIGKGRFGEVWRG--RWRGENVAVK---IFSSREECSWFR--EAEIYQTVMLRHENILGF 236 +IG G FG V+R G+ +AVK + R + + E+ + H N++ + Sbjct: 1125 LIGSGSFGTVYRAVNLDTGDLMAVKEVALHKPRISRPMIKRIKGEMLVLELFDHPNVVSY 1184 Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMS-LSIATGLAHLHMDIV 295 + ++ + + + SLF+FL I+ +I++ L + GLA++H Sbjct: 1185 YGIEVHRE----KVNIFMELCQGSSLFEFLRYGRIEDELVIQVYVLQLLEGLAYIH---- 1236 Query: 296 GTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLA 329 ++H+D+K +NIL N D G A Sbjct: 1237 ----SCGVSHQDVKPENILFDHNGIMKFTDFGSA 1266 >SPAC20G4.03c |hri1||eIF2 alpha kinase Hri1|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 32.7 bits (71), Expect = 0.12 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 323 IGDLGLAVRH--NVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGL 380 IGD GL + N+ + ++ VGT Y APE+ + M + + +D+Y+ G+ Sbjct: 541 IGDFGLVLSQSDNLEEGTNSSAESSFVGTSTYAAPELFSKHMRS-VMNNNSSTDIYALGI 599 Query: 381 VLWEM 385 + +E+ Sbjct: 600 LFFEL 604 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 32.3 bits (70), Expect = 0.15 Identities = 50/208 (24%), Positives = 85/208 (40%), Gaps = 18/208 (8%) Query: 124 WRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELTTSGSGSGLPLLVQRS-IARQIQLV 182 +R KR +P + + N P + +T G +V S A + +V Sbjct: 307 YRPPKKRKRAAWPPYKKVDRV-NVPVVHDTTAFDPSTFDDDDGHYKVVPNSKFANRYTVV 365 Query: 183 DIIGKGRFGEVWR--GRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA-A 239 ++G G FG+V + + G + A+K+ + + +REA + + LR +L IA + Sbjct: 366 RLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPK---YREASLIE---LR---VLQTIAHS 416 Query: 240 DNKDNGTWTQLWLITDYHEN----GSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV 295 D + QL DY ++ LF + + +N I L L+ V Sbjct: 417 DPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSV 476 Query: 296 GTKGKPAIAHRDLKSKNILVKSNLSCVI 323 + H DLK +N+L+ SN S I Sbjct: 477 AFLHSLGLVHTDLKPENVLLVSNASRTI 504 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 31.1 bits (67), Expect = 0.35 Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 12/149 (8%) Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFREAEIY-QTVMLRHENILGFIAADN 241 I KG FG V+ + R G+ A+KI + + + + +L + F+A Sbjct: 595 ISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGESPFVAKLY 654 Query: 242 KDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300 + L+L+ +Y G L T +D + + L LH +G Sbjct: 655 YTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDLH-----DRG- 708 Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLA 329 I HRD+K +N+L+ N + D GL+ Sbjct: 709 --IIHRDIKPENLLISQNGHLKLTDFGLS 735 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 31.1 bits (67), Expect = 0.35 Identities = 44/217 (20%), Positives = 80/217 (36%), Gaps = 20/217 (9%) Query: 134 PYPDEDETKHILNTPTTTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEV 193 P+ E E HI T T R S + + + + V ++GKG G V Sbjct: 157 PHGKEKELAHIKKTVATRARTY-------SSNSIKICDVEVGPSSFEKVFLLGKGDVGRV 209 Query: 194 W--RGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLW 251 + R + G+ A+K+ S +E + + + + FI + L+ Sbjct: 210 YLVREKKSGKFYAMKVLSKQEMIKRNKSKRAFAEQHILATSNHPFIVTLYHSFQSDEYLY 269 Query: 252 LITDYHENGSLFDFLT---AKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDL 308 L +Y G F L + + N + L +LH+ +RDL Sbjct: 270 LCMEYCMGGEFFRALQRRPGRCLSENEAKFYIAEVTAALEYLHL--------MGFIYRDL 321 Query: 309 KSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTN 345 K +NIL+ + ++ D L+ + N + + + N Sbjct: 322 KPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARN 358 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 30.7 bits (66), Expect = 0.47 Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 10/93 (10%) Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETM 362 I HRDLK N+L+ S+ + D GL+ + +++V T+ Y PE+ M Sbjct: 129 ILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSH-----MSHQVITRWYRPPELF---M 180 Query: 363 DTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395 R + D++S G + E+ R +P + Sbjct: 181 GCRSYG--TGVDMWSVGCIFAELMLRTPYLPGE 211 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 30.3 bits (65), Expect = 0.62 Identities = 33/110 (30%), Positives = 50/110 (45%), Gaps = 13/110 (11%) Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309 ++LIT + ++ L D + SID T K+ L I++ L +L K I HRD+ Sbjct: 83 VYLITSF-KSFVLSDVMDEISID--TKCKIVLQISSALEYLE--------KHGILHRDIH 131 Query: 310 SKNILVKS-NLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVL 358 NIL+ S N + D +A + V ++GT Y A E L Sbjct: 132 PNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQ-ELIPQIGTGHYRAIETL 180 >SPAC1834.08 |mak1|phk3|histidine kinase Mak1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1639 Score = 29.9 bits (64), Expect = 0.81 Identities = 15/62 (24%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Query: 241 NKDNGTWTQLWL--ITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH-LHMDIVGT 297 N T T LWL TD H++ L + L +I++ +++ + + ++H + ++G Sbjct: 953 NNSADTSTNLWLGTCTDIHDHKMLEEKLQESNIEAQRIVRSKMQYLSNMSHEIRTPLIGI 1012 Query: 298 KG 299 G Sbjct: 1013 TG 1014 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 29.5 bits (63), Expect = 1.1 Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Query: 175 IARQIQLVDIIGKGRFGEVWR--GRWRGENVAVKIFSSRE 212 IA + ++VD +GKG FG+V R G+ VA+KI +++ Sbjct: 695 IAYRYEVVDFLGKGSFGQVLRCIDYETGKLVALKIIRNKK 734 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 29.1 bits (62), Expect = 1.4 Identities = 36/161 (22%), Positives = 68/161 (42%), Gaps = 23/161 (14%) Query: 185 IGKGRFGEVWRGRWRG--ENVAVKIFSSREECSWFREAE--IYQTVMLRHEN----ILGF 236 +G+G +G VW + R E +A+K+ + E + + + +L + N + + Sbjct: 168 LGQGGYGSVWLAKKRNTHELLAMKMMK-KSTLQQLNEVKHILNERDILTNTNSEWLVKLY 226 Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLS-IATGLAHLHMDIV 295 A +K+ +++L +Y G FLT K + + L+ + ++ +H Sbjct: 227 YAFQDKE-----KVYLAMEYVPGGDFRTFLTTKGLLHENQTRFYLAEMVAAISAVH---- 277 Query: 296 GTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336 K HRDLK +N L+ + D GL+ SN Sbjct: 278 ----KLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSN 314 >SPAPJ760.02c |app1||App1 protein|Schizosaccharomyces pombe|chr 1|||Manual Length = 857 Score = 28.3 bits (60), Expect = 2.5 Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 11/72 (15%) Query: 202 NVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGS 261 NV K+ S ++CSW Y+ NIL +A+ N DN + + ++ EN Sbjct: 16 NVYEKVLSGADDCSWAIFG--YEK---GQGNILKVVASGN-DNDEF-----LDEFDENAV 64 Query: 262 LFDFLTAKSIDS 273 LF FL K +++ Sbjct: 65 LFGFLRVKDVNT 76 >SPAC869.03c |||urea transporter |Schizosaccharomyces pombe|chr 1|||Manual Length = 661 Score = 28.3 bits (60), Expect = 2.5 Identities = 10/21 (47%), Positives = 13/21 (61%) Query: 97 AWQVVPWIMGLVVFAICVALS 117 AW +VPW MG C+AL+ Sbjct: 294 AWLIVPWAMGSAAALSCLALT 314 >SPCC1902.01 |gaf1|SPCC417.01c|transcription factor Gaf1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 855 Score = 27.9 bits (59), Expect = 3.3 Identities = 16/65 (24%), Positives = 29/65 (44%) Query: 304 AHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMD 363 + + KS+++L +NL+ + D GL + + +D ++ V K AP V D Sbjct: 759 SENESKSQSMLSANNLNAGVNDFGLGFSEGLGSAHLDSNDSSMVQGKNDFAPVVDSPLFD 818 Query: 364 TRQFD 368 D Sbjct: 819 AFDTD 823 >SPAC890.04c |||ribosome biogenesis protein Ytm1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 440 Score = 27.9 bits (59), Expect = 3.3 Identities = 15/58 (25%), Positives = 27/58 (46%), Gaps = 1/58 (1%) Query: 263 FDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLS 320 +D +T +++DS + K L L LH+ I G+ + + H + +V LS Sbjct: 296 WDLITGQNVDSK-ITKAPLLCVEKLTDLHLVICGSSARHIVVHDPRAGSDKIVSHTLS 352 >SPBC56F2.04 |utp20||U3 snoRNP protein Utp20|Schizosaccharomyces pombe|chr 2|||Manual Length = 2493 Score = 27.5 bits (58), Expect = 4.3 Identities = 21/91 (23%), Positives = 37/91 (40%), Gaps = 1/91 (1%) Query: 266 LTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGD 325 L ++ SN L+ + + T LH I T I H +I + +L+ ++ Sbjct: 1240 LVPSNVKSNILVLLCKLLPTNTKWLHASISQTNDFDTIMHLYTSMVDIKARQHLNDLL-K 1298 Query: 326 LGLAVRHNVSNDSVDVPSTNRVGTKRYMAPE 356 + + N+ SV V N + KR P+ Sbjct: 1299 IYSTIDDNLIFSSVFVEEINSISKKRLDEPD 1329 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 27.5 bits (58), Expect = 4.3 Identities = 48/209 (22%), Positives = 89/209 (42%), Gaps = 26/209 (12%) Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAA--DN 241 ++G G FG V + + I ++ F+ E+ +++H NI+ IA Sbjct: 37 VVGSGSFGVVMQVHLIESDSKAAIKRVLQD-KRFKNRELQIMRIMKHPNIVDLIAYYYTT 95 Query: 242 KDNGTWTQLWLITDYH-ENGSLFDFLTAKSIDSNTLIKMSLSI---ATGLAHLHMDIVGT 297 DN L L+ ++ E L + S ++++ L I LA++H Sbjct: 96 GDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIHAS---- 151 Query: 298 KGKPAIAHRDLKSKNILV-KSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPE 356 I HRD+K +N+L+ N + D G A + V+ + P+ + + ++ Y APE Sbjct: 152 ----GICHRDIKPQNLLLDPENGILKLCDFGSA-KILVAGE----PNVSYICSRYYRAPE 202 Query: 357 VLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 ++ D D++S G V+ E+ Sbjct: 203 LIFGATDYTH-----AIDIWSTGCVMAEL 226 >SPAC23H3.06 |apl6||AP-3 adaptor complex subunit Apl6 |Schizosaccharomyces pombe|chr 1|||Manual Length = 745 Score = 27.1 bits (57), Expect = 5.7 Identities = 12/42 (28%), Positives = 22/42 (52%) Query: 430 WHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTNG 471 ++ D L ++ V K + +NP R TA+R+ ++ NG Sbjct: 99 FNPDLALLSVNTVQKTLYDKNPLTRSTAIRVMSSIRVPAING 140 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 27.1 bits (57), Expect = 5.7 Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 5/49 (10%) Query: 334 VSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVL 382 + ND+ NR GT+ + APEVL + + D++S G++L Sbjct: 276 IKNDTRPSKRANRAGTRGFRAPEVLFKCSSQS-----PKVDIWSAGVIL 319 >SPBC4B4.01c |||fumble family pantothenate kinase |Schizosaccharomyces pombe|chr 2|||Manual Length = 403 Score = 26.6 bits (56), Expect = 7.6 Identities = 24/94 (25%), Positives = 42/94 (44%), Gaps = 9/94 (9%) Query: 145 LNTPTTTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVA 204 L TP + +M+EL+ G + + +LV + IG RFG + + Sbjct: 244 LLTPANSFDEMLELSKGGDNTSVDMLVGDIYGKD------IGYERFG--LKSTTIASSFG 295 Query: 205 VKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238 K+F R+ F +I ++++L N +G IA Sbjct: 296 -KVFRERKPLEEFAPQDISRSLLLAISNNIGQIA 328 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 26.6 bits (56), Expect = 7.6 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 7/38 (18%) Query: 348 GTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385 GT YMAPE+L +DT+ D+++ G V++EM Sbjct: 779 GTPNYMAPEIL-MGVDTQM------GDIWAMGCVIFEM 809 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.321 0.136 0.441 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 2,435,012 Number of Sequences: 5004 Number of extensions: 108086 Number of successful extensions: 378 Number of sequences better than 10.0: 92 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 259 Number of HSP's gapped (non-prelim): 113 length of query: 477 length of database: 2,362,478 effective HSP length: 75 effective length of query: 402 effective length of database: 1,987,178 effective search space: 798845556 effective search space used: 798845556 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.9 bits) S2: 56 (26.6 bits)
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