Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000601-TA|BGIBMGA000601-PA|IPR011009|Protein
kinase-like, IPR000719|Protein kinase, IPR008271|Serine/threonine
protein kinase, active site, IPR000472|TGF-beta receptor/activin
receptor, type I/II, IPR003605|TGF beta receptor, GS motif,
IPR002290|Serine/threonine protein kinase, IPR000333|Activin type II
receptor
(477 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L11695-1|AAA16073.1| 503|Homo sapiens activin receptor-like kin... 501 e-141
DQ383424-1|ABD46753.1| 503|Homo sapiens transforming growth fac... 501 e-141
AY497473-1|AAR32097.1| 503|Homo sapiens transforming growth fac... 501 e-141
AL162427-1|CAI17140.1| 503|Homo sapiens transforming growth fac... 501 e-141
AF054598-1|AAC08998.1| 503|Homo sapiens TGF-beta type I recepto... 501 e-141
AF035670-1|AAD02042.1| 503|Homo sapiens transforming growth fac... 501 e-141
Z22536-1|CAA80258.1| 505|Homo sapiens ALK-4 protein. 491 e-138
U14722-1|AAA50246.1| 505|Homo sapiens activin type I receptor p... 491 e-138
BT007072-1|AAP35735.1| 505|Homo sapiens activin A receptor, typ... 491 e-138
BC040531-1|AAH40531.1| 505|Homo sapiens activin A receptor, typ... 491 e-138
BC000254-1|AAH00254.1| 505|Homo sapiens activin A receptor, typ... 491 e-138
AY127050-1|AAM93495.1| 493|Homo sapiens activin receptor-like k... 479 e-134
AF525679-1|AAP21993.1| 443|Homo sapiens truncated activin recep... 479 e-134
AC079750-1|AAX88951.1| 468|Homo sapiens unknown protein. 479 e-134
Z22534-1|CAA80256.1| 509|Homo sapiens ALK-2 protein. 477 e-134
L02911-1|AAA36614.1| 509|Homo sapiens serine kinase receptor pr... 477 e-134
BC033867-1|AAH33867.1| 509|Homo sapiens ACVR1 protein protein. 477 e-134
BC022530-1|AAH22530.1| 493|Homo sapiens activin A receptor, typ... 477 e-134
BC071181-1|AAH71181.1| 426|Homo sapiens TGFBR1 protein protein. 469 e-131
Z22535-1|CAA80257.1| 532|Homo sapiens ALK-3 protein. 458 e-128
BC028383-1|AAH28383.1| 532|Homo sapiens bone morphogenetic prot... 458 e-128
AF525680-1|AAP21994.1| 413|Homo sapiens soluble activin recepto... 448 e-125
U89326-1|AAC28131.1| 502|Homo sapiens bone morphogenetic protei... 444 e-124
D89675-1|BAA19765.1| 502|Homo sapiens bone morphogenetic protei... 444 e-124
BC069803-1|AAH69803.1| 502|Homo sapiens bone morphogenetic prot... 444 e-124
BC069796-1|AAH69796.1| 502|Homo sapiens bone morphogenetic prot... 444 e-124
BC047773-1|AAH47773.1| 502|Homo sapiens BMPR1B protein protein. 444 e-124
L10125-1|AAA60555.1| 476|Homo sapiens activin type I receptor p... 441 e-123
Z22533-1|CAA80255.1| 503|Homo sapiens ALK-1 protein. 437 e-122
U77713-1|AAB61900.1| 503|Homo sapiens activin receptor like kin... 436 e-121
L17075-1|AAA16160.1| 503|Homo sapiens TGF-b superfamily recepto... 436 e-121
BC042637-1|AAH42637.1| 503|Homo sapiens activin A receptor type... 436 e-121
L10126-1|AAA60556.1| 487|Homo sapiens activin type I receptor p... 383 e-106
AF525681-1|AAP21995.1| 336|Homo sapiens soluble activin recepto... 311 4e-84
AC013731-1|AAY24272.1| 355|Homo sapiens unknown protein. 273 1e-72
L31848-1|AAA53351.1| 212|Homo sapiens activin type I receptor S... 270 9e-72
X63128-1|CAA44839.1| 513|Homo sapiens activin receptor protein. 237 5e-62
X62381-1|CAA44245.1| 513|Homo sapiens activin receptor protein. 237 5e-62
M93415-1|AAA35504.1| 513|Homo sapiens activin type II receptor ... 237 5e-62
BC069707-1|AAH69707.1| 513|Homo sapiens activin A receptor, typ... 237 5e-62
BC067418-1|AAH67418.1| 513|Homo sapiens activin A receptor, typ... 237 5e-62
BC067417-1|AAH67417.1| 513|Homo sapiens activin A receptor, typ... 237 5e-62
AC009480-2|AAX93050.1| 513|Homo sapiens unknown protein. 237 5e-62
D31770-1|BAA06548.1| 513|Homo sapiens activin typeII A receptor... 233 8e-61
X77533-1|CAA54671.1| 512|Homo sapiens activin type II receptor ... 230 7e-60
BC099642-1|AAH99642.1| 512|Homo sapiens activin A receptor, typ... 230 7e-60
BC096244-1|AAH96244.1| 512|Homo sapiens activin A receptor, typ... 230 7e-60
BC096243-1|AAH96243.1| 512|Homo sapiens activin A receptor, typ... 230 7e-60
AB209449-1|BAD92686.1| 514|Homo sapiens activin A type IIB rece... 230 7e-60
AB008681-1|BAA24180.2| 512|Homo sapiens activin receptor type I... 229 2e-59
DQ377559-1|ABG65632.1| 567|Homo sapiens transforming growth fac... 229 2e-59
AY675319-1|AAT70724.1| 567|Homo sapiens transforming growth fac... 229 2e-59
U69152-1|AAB40916.1| 567|Homo sapiens transforming growth facto... 228 3e-59
U52246-1|AAB17553.1| 567|Homo sapiens transforming growth facto... 228 3e-59
M85079-1|AAA61164.1| 567|Homo sapiens TGF-beta type II receptor... 228 3e-59
L31848-2|AAA53350.1| 183|Homo sapiens activin type I receptor S... 228 3e-59
AF060202-1|AAC64515.1| 512|Homo sapiens activin receptor type I... 228 4e-59
D50683-1|BAA09332.1| 567|Homo sapiens TGF-betaIIR alpha protein. 226 1e-58
BC096245-1|AAH96245.1| 303|Homo sapiens ACVR2B protein protein. 210 1e-53
AC019186-2|AAY15094.1| 153|Homo sapiens unknown protein. 205 2e-52
Z48923-1|CAA88759.1| 1038|Homo sapiens BMPR-II precursor protein. 190 1e-47
U25110-1|AAA86519.1| 530|Homo sapiens bone morphogenic protein ... 190 1e-47
U20165-1|AAC50105.1| 1038|Homo sapiens type II serine/threonine ... 190 1e-47
D50516-1|BAA09094.1| 1038|Homo sapiens type II receptor for bone... 190 1e-47
BC052985-1|AAH52985.1| 1038|Homo sapiens bone morphogenetic prot... 190 1e-47
X91156-1|CAA62593.1| 573|Homo sapiens antimullerian hormone typ... 177 5e-44
X89013-1|CAA61418.1| 573|Homo sapiens anti-mullerian hormone ty... 177 5e-44
U29700-1|AAC50328.1| 573|Homo sapiens anti-mullerian hormone ty... 177 5e-44
BC126316-1|AAI26317.1| 573|Homo sapiens anti-Mullerian hormone ... 177 5e-44
AF172932-1|AAD48497.1| 573|Homo sapiens MIS type II receptor pr... 177 5e-44
L31848-3|AAA53349.1| 194|Homo sapiens activin type I receptor S... 170 8e-42
AC009960-1|AAX76517.1| 715|Homo sapiens unknown protein. 121 6e-27
AY714878-1|AAU21221.1| 478|Homo sapiens anti-Mullerian hormone ... 103 2e-21
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 97 1e-19
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 97 1e-19
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 97 1e-19
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 97 1e-19
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 97 1e-19
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 97 1e-19
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 97 1e-19
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 97 1e-19
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 94 1e-18
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 91 1e-17
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 91 1e-17
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 91 1e-17
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 91 1e-17
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 87 1e-16
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 87 1e-16
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 87 1e-16
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 87 1e-16
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 87 1e-16
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 87 1e-16
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 87 1e-16
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 87 1e-16
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 87 1e-16
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 87 1e-16
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 87 1e-16
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 86 2e-16
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 86 3e-16
BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting se... 85 4e-16
AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting pr... 85 4e-16
AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens ... 85 4e-16
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 85 5e-16
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 85 5e-16
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 85 5e-16
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 85 5e-16
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 85 5e-16
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 85 5e-16
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 85 5e-16
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 85 5e-16
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 85 5e-16
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 84 9e-16
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 84 9e-16
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 84 9e-16
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 84 9e-16
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 84 9e-16
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 84 9e-16
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 84 9e-16
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 84 1e-15
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 83 2e-15
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 83 2e-15
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 83 2e-15
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 83 2e-15
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 83 2e-15
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 83 2e-15
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 83 2e-15
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 83 2e-15
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 83 2e-15
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 82 4e-15
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 82 4e-15
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 82 4e-15
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 82 4e-15
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 81 6e-15
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 81 6e-15
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 81 6e-15
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 81 6e-15
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 81 6e-15
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 81 6e-15
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 81 6e-15
AF156884-1|AAD39005.1| 518|Homo sapiens RIP-like kinase protein. 81 6e-15
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 81 8e-15
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 81 8e-15
BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and... 81 8e-15
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 81 8e-15
AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage kinase-re... 81 8e-15
AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage kinase-re... 81 8e-15
AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppres... 81 8e-15
AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase pr... 81 8e-15
AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and... 81 8e-15
AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZA... 81 8e-15
AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage... 81 8e-15
AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein. 81 8e-15
AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein. 81 8e-15
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 81 8e-15
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 81 8e-15
AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage... 81 8e-15
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 79 3e-14
BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein. 79 3e-14
AL451136-3|CAI13092.1| 542|Homo sapiens testis-specific kinase ... 79 3e-14
AL451136-2|CAI13093.1| 571|Homo sapiens testis-specific kinase ... 79 3e-14
AL359540-13|CAI21723.1| 542|Homo sapiens testis-specific kinase... 79 3e-14
AL359540-12|CAI21724.1| 571|Homo sapiens testis-specific kinase... 79 3e-14
AB057597-1|BAB62909.1| 571|Homo sapiens testicular protein kina... 79 3e-14
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 79 3e-14
U43586-1|AAC50354.1| 635|Homo sapiens KSR1 protein. 79 3e-14
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 79 3e-14
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 79 3e-14
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 79 3e-14
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 79 3e-14
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 79 3e-14
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 79 3e-14
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 79 3e-14
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 79 3e-14
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 79 3e-14
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 79 3e-14
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 79 3e-14
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 79 3e-14
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 79 3e-14
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 79 4e-14
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 79 4e-14
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 79 4e-14
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 79 4e-14
AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kin... 79 4e-14
AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 79 4e-14
AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 79 4e-14
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 79 4e-14
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 79 4e-14
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 79 4e-14
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 79 4e-14
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 79 4e-14
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 79 4e-14
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 79 4e-14
AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK... 79 4e-14
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 79 4e-14
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 79 4e-14
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 79 4e-14
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 78 6e-14
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 78 6e-14
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 78 6e-14
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 78 6e-14
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 78 6e-14
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 78 8e-14
AC073410-1|AAX88941.1| 296|Homo sapiens unknown protein. 78 8e-14
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 78 8e-14
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 77 1e-13
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 77 1e-13
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 77 1e-13
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 77 1e-13
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 77 1e-13
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 77 2e-13
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 77 2e-13
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 77 2e-13
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 77 2e-13
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 77 2e-13
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 76 2e-13
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 76 2e-13
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 76 2e-13
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 76 2e-13
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 76 2e-13
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 76 2e-13
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 76 2e-13
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 76 2e-13
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 75 4e-13
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 75 4e-13
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 75 4e-13
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 75 4e-13
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 75 4e-13
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 75 4e-13
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 75 4e-13
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 75 4e-13
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 75 4e-13
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 75 4e-13
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 75 4e-13
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 75 4e-13
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 75 4e-13
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 75 4e-13
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 75 4e-13
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 75 6e-13
U63721-3|AAC13886.1| 633|Homo sapiens LIM-kinase protein. 75 7e-13
U63721-2|AAC13885.1| 647|Homo sapiens LIM-kinase protein. 75 7e-13
U62293-2|AAB17546.1| 633|Homo sapiens alternatively spliced LIM... 75 7e-13
U62293-1|AAB17545.1| 647|Homo sapiens LIM-kinase1 protein. 75 7e-13
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 75 7e-13
D26309-1|BAA05371.1| 647|Homo sapiens LIM kinase protein. 75 7e-13
BC127603-1|AAI27604.1| 829|Homo sapiens kinase suppressor of ra... 75 7e-13
BC107107-1|AAI07108.1| 827|Homo sapiens KSR2 protein protein. 75 7e-13
BC107106-1|AAI07107.1| 827|Homo sapiens KSR2 protein protein. 75 7e-13
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 75 7e-13
AY345972-1|AAQ24226.1| 829|Homo sapiens kinase suppressor of Ra... 75 7e-13
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 75 7e-13
AC005057-3|AAS07438.1| 596|Homo sapiens unknown protein. 75 7e-13
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 73 2e-12
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 73 2e-12
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 73 2e-12
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 73 2e-12
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 73 2e-12
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 73 2e-12
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 73 2e-12
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 73 2e-12
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 73 2e-12
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 73 2e-12
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 73 2e-12
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 73 2e-12
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 73 2e-12
AY494982-1|AAS75516.1| 252|Homo sapiens RIP3 beta protein. 73 2e-12
AY494983-1|AAS75517.1| 231|Homo sapiens RIP3 gamma protein. 73 3e-12
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 72 4e-12
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 72 4e-12
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 72 4e-12
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 72 4e-12
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 72 4e-12
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 72 4e-12
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 72 4e-12
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 72 4e-12
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 72 4e-12
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 72 5e-12
U50062-1|AAC32232.1| 671|Homo sapiens RIP protein kinase protein. 72 5e-12
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 72 5e-12
BC126256-1|AAI26257.1| 671|Homo sapiens receptor (TNFRSF)-inter... 72 5e-12
BC126254-1|AAI26255.1| 671|Homo sapiens receptor (TNFRSF)-inter... 72 5e-12
AY682848-1|AAT74626.1| 671|Homo sapiens receptor (TNFRSF)-inter... 72 5e-12
AL031963-3|CAD70625.1| 671|Homo sapiens receptor (TNFRSF)-inter... 72 5e-12
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 72 5e-12
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 71 1e-11
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 71 1e-11
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 70 2e-11
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 70 2e-11
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 70 2e-11
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 70 2e-11
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 70 2e-11
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 70 2e-11
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 70 2e-11
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 70 2e-11
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 70 2e-11
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 70 2e-11
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 70 2e-11
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 70 2e-11
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 70 2e-11
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 70 2e-11
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 69 4e-11
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 69 4e-11
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 69 4e-11
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 69 4e-11
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 69 4e-11
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 69 4e-11
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 69 4e-11
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 69 4e-11
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 69 4e-11
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 69 5e-11
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 69 5e-11
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 69 5e-11
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 68 6e-11
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 68 6e-11
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 68 6e-11
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 68 6e-11
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 68 6e-11
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 68 6e-11
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 68 8e-11
BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein pr... 68 8e-11
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 68 8e-11
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 68 8e-11
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 68 8e-11
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 68 8e-11
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 68 8e-11
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 68 8e-11
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 68 8e-11
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 68 8e-11
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 68 8e-11
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 68 8e-11
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 68 8e-11
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 68 8e-11
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 68 8e-11
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 68 8e-11
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 67 1e-10
U40282-1|AAC16892.1| 452|Homo sapiens integrin-linked kinase pr... 67 1e-10
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 67 1e-10
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 67 1e-10
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 67 1e-10
CR407673-1|CAG28601.1| 452|Homo sapiens ILK protein. 67 1e-10
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 67 1e-10
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 67 1e-10
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 67 1e-10
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 67 1e-10
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 67 1e-10
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 67 1e-10
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 67 1e-10
BC001554-1|AAH01554.1| 452|Homo sapiens integrin-linked kinase ... 67 1e-10
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 67 1e-10
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 67 1e-10
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 67 1e-10
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 67 1e-10
AK131529-1|BAD18667.1| 879|Homo sapiens protein ( Homo sapiens ... 67 1e-10
AJ404847-1|CAB99253.1| 452|Homo sapiens integrin-linked kinase ... 67 1e-10
AF244139-1|AAF74449.1| 452|Homo sapiens integrin-linked kinase ... 67 1e-10
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 67 1e-10
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 67 1e-10
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 67 1e-10
AB014541-1|BAA31616.2| 1326|Homo sapiens KIAA0641 protein protein. 67 1e-10
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 67 1e-10
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 67 1e-10
X80230-1|CAA56516.1| 372|Homo sapiens serine/threonine protein ... 66 2e-10
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 66 2e-10
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 66 2e-10
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 66 2e-10
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 66 2e-10
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 66 2e-10
L25676-1|AAA35668.1| 372|Homo sapiens CDC2-related kinase protein. 66 2e-10
BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a prote... 66 2e-10
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 66 2e-10
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 66 2e-10
BC001968-1|AAH01968.1| 372|Homo sapiens cyclin-dependent kinase... 66 2e-10
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 66 2e-10
AL162586-9|CAI39768.1| 372|Homo sapiens cyclin-dependent kinase... 66 2e-10
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 66 2e-10
AF517840-1|AAM54039.1| 372|Homo sapiens cyclin-dependent kinase... 66 2e-10
AF255306-1|AAF72183.1| 372|Homo sapiens protein kinase CDK9 pro... 66 2e-10
AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant ... 66 2e-10
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 66 3e-10
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 66 3e-10
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 66 3e-10
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 66 3e-10
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 66 3e-10
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 66 3e-10
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 66 3e-10
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 66 3e-10
AB209655-1|BAD92892.1| 310|Homo sapiens mitogen-activated prote... 66 3e-10
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 66 3e-10
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 66 3e-10
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 66 3e-10
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 66 3e-10
BT019903-1|AAV38706.1| 372|Homo sapiens cyclin-dependent kinase... 66 3e-10
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 66 3e-10
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 66 3e-10
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 66 3e-10
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 66 3e-10
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 66 3e-10
AC013461-1|AAX93067.1| 400|Homo sapiens unknown protein. 66 3e-10
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 65 4e-10
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 65 6e-10
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 65 6e-10
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 65 6e-10
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 65 6e-10
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 65 6e-10
AB219242-1|BAE02826.1| 1141|Homo sapiens janus kinase 1 protein. 65 6e-10
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 65 6e-10
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 65 6e-10
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 64 8e-10
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 64 8e-10
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 64 8e-10
AJ316534-1|CAC48387.1| 1231|Homo sapiens serine/threonine protei... 64 8e-10
AJ132545-1|CAB41970.1| 555|Homo sapiens protein kinase protein. 64 8e-10
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 64 8e-10
AF390018-1|AAK91995.1| 1243|Homo sapiens putative protein kinase... 64 8e-10
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 64 8e-10
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 64 1e-09
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 64 1e-09
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 64 1e-09
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 64 1e-09
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 64 1e-09
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 64 1e-09
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 64 1e-09
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 64 1e-09
AJ277481-1|CAB94832.1| 452|Homo sapiens integrin-linked kinase-... 64 1e-09
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 64 1e-09
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 64 1e-09
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 63 2e-09
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 63 2e-09
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 63 2e-09
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 63 2e-09
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 63 2e-09
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 63 2e-09
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 63 2e-09
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 63 2e-09
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 63 2e-09
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 63 2e-09
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 63 2e-09
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 63 2e-09
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 63 2e-09
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 63 2e-09
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 63 2e-09
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 63 2e-09
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 63 2e-09
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 63 2e-09
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 63 2e-09
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 63 2e-09
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 63 2e-09
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 63 2e-09
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 63 2e-09
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 63 2e-09
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 63 2e-09
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 63 2e-09
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 63 2e-09
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 63 2e-09
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 63 2e-09
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 63 2e-09
AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein. 63 2e-09
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 63 2e-09
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 62 3e-09
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 62 3e-09
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 62 3e-09
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 62 3e-09
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 62 4e-09
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 62 4e-09
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 62 4e-09
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 62 4e-09
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 62 4e-09
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 62 4e-09
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 62 4e-09
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 62 4e-09
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 62 4e-09
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 62 4e-09
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 62 4e-09
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 62 4e-09
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 62 4e-09
>L11695-1|AAA16073.1| 503|Homo sapiens activin receptor-like kinase
protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>DQ383424-1|ABD46753.1| 503|Homo sapiens transforming growth factor
beta receptor I protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>AY497473-1|AAR32097.1| 503|Homo sapiens transforming growth
factor, beta receptor I (activin A receptor type II-like
ki protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>AL162427-1|CAI17140.1| 503|Homo sapiens transforming growth
factor, beta receptor I (activin A receptor type II-like
ki protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>AF054598-1|AAC08998.1| 503|Homo sapiens TGF-beta type I receptor
protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>AF035670-1|AAD02042.1| 503|Homo sapiens transforming growth
factor-beta type I receptor protein.
Length = 503
Score = 501 bits (1235), Expect = e-141
Identities = 243/420 (57%), Positives = 311/420 (74%), Gaps = 10/420 (2%)
Query: 55 PGDKPVWCREDERSDII----CCASDYCNRDIFAEFWIKETSPTATAWQVVPWIMGLVVF 110
P D+P C ++ + CC D+CN+ I +K +SP ++ I G V F
Sbjct: 79 PRDRPFVCAPSSKTGSVTTTYCCNQDHCNK-IELPTTVK-SSPGLGPVELAAVIAGPVCF 136
Query: 111 AICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPL 169
+C++L L P ++ + TT++D+I ++TTSGSGSGLPL
Sbjct: 137 -VCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPL 195
Query: 170 LVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLR 229
LVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQTVMLR
Sbjct: 196 LVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLR 255
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAH 289
HENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLAH
Sbjct: 256 HENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAH 315
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+ +RVGT
Sbjct: 316 LHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGT 375
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPD 407
KRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD VP D
Sbjct: 376 KRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSD 435
Query: 408 PALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
P++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKKTL+ +
Sbjct: 436 PSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQL 495
>Z22536-1|CAA80258.1| 505|Homo sapiens ALK-4 protein.
Length = 505
Score = 491 bits (1211), Expect = e-138
Identities = 238/421 (56%), Positives = 303/421 (71%), Gaps = 8/421 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEVWRGRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ GLV WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLAN 466
DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AARLTALRIKKTL+
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496
Query: 467 V 467
+
Sbjct: 497 L 497
>U14722-1|AAA50246.1| 505|Homo sapiens activin type I receptor
protein.
Length = 505
Score = 491 bits (1211), Expect = e-138
Identities = 238/421 (56%), Positives = 303/421 (71%), Gaps = 8/421 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEVWRGRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ GLV WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLAN 466
DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AARLTALRIKKTL+
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496
Query: 467 V 467
+
Sbjct: 497 L 497
>BT007072-1|AAP35735.1| 505|Homo sapiens activin A receptor, type
IB protein.
Length = 505
Score = 491 bits (1211), Expect = e-138
Identities = 238/421 (56%), Positives = 303/421 (71%), Gaps = 8/421 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEVWRGRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ GLV WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLAN 466
DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AARLTALRIKKTL+
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496
Query: 467 V 467
+
Sbjct: 497 L 497
>BC040531-1|AAH40531.1| 505|Homo sapiens activin A receptor, type
IB protein.
Length = 505
Score = 491 bits (1211), Expect = e-138
Identities = 238/421 (56%), Positives = 303/421 (71%), Gaps = 8/421 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEVWRGRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ GLV WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLAN 466
DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AARLTALRIKKTL+
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496
Query: 467 V 467
+
Sbjct: 497 L 497
>BC000254-1|AAH00254.1| 505|Homo sapiens activin A receptor, type
IB protein.
Length = 505
Score = 491 bits (1211), Expect = e-138
Identities = 238/421 (56%), Positives = 303/421 (71%), Gaps = 8/421 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEVWRGRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ GLV WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLAN 466
DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AARLTALRIKKTL+
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAARLTALRIKKTLSQ 496
Query: 467 V 467
+
Sbjct: 497 L 497
>AY127050-1|AAM93495.1| 493|Homo sapiens activin receptor-like
kinase 7 protein.
Length = 493
Score = 479 bits (1180), Expect = e-134
Identities = 224/400 (56%), Positives = 299/400 (74%), Gaps = 4/400 (1%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTATAWQVVPWI-MGLVVFAICVALSLWWAKKWRADGKR 130
CC +D+CN +P ++ I + + + +I L++W + + ++
Sbjct: 86 CCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRK 145
Query: 131 PPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGR 189
RP +E ++ L T++D+I ++T SGSGSGLPLLVQR+IAR I L +I+GKGR
Sbjct: 146 KKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGR 205
Query: 190 FGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 249
FGEVW GRW GE+VAVKIFSSR+E SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ
Sbjct: 206 FGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 265
Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309
LWL+++YHE GSL+D+L + +IK++LSIA+GLAHLHM+IVGT+GKPAIAHRD+K
Sbjct: 266 LWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 325
Query: 310 SKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDP 369
SKNILVK +C I DLGLAV+H+ +++D+P +VGTKRYMAPE+LD+TM+ F+
Sbjct: 326 SKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFES 385
Query: 370 YKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVP 427
+KR+D+YS GLV WE+ARRC G + ++YQ PYYD VP DP++E+MR+VVC +K RP++P
Sbjct: 386 FKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIP 445
Query: 428 NRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
N+W S L + ++M+ECWY N AARLTALRIKKT++ +
Sbjct: 446 NQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 485
>AF525679-1|AAP21993.1| 443|Homo sapiens truncated activin
receptor-like kinase 7 protein.
Length = 443
Score = 479 bits (1180), Expect = e-134
Identities = 224/400 (56%), Positives = 299/400 (74%), Gaps = 4/400 (1%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTATAWQVVPWI-MGLVVFAICVALSLWWAKKWRADGKR 130
CC +D+CN +P ++ I + + + +I L++W + + ++
Sbjct: 36 CCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRK 95
Query: 131 PPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGR 189
RP +E ++ L T++D+I ++T SGSGSGLPLLVQR+IAR I L +I+GKGR
Sbjct: 96 KKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGR 155
Query: 190 FGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 249
FGEVW GRW GE+VAVKIFSSR+E SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ
Sbjct: 156 FGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 215
Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309
LWL+++YHE GSL+D+L + +IK++LSIA+GLAHLHM+IVGT+GKPAIAHRD+K
Sbjct: 216 LWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 275
Query: 310 SKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDP 369
SKNILVK +C I DLGLAV+H+ +++D+P +VGTKRYMAPE+LD+TM+ F+
Sbjct: 276 SKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFES 335
Query: 370 YKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVP 427
+KR+D+YS GLV WE+ARRC G + ++YQ PYYD VP DP++E+MR+VVC +K RP++P
Sbjct: 336 FKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIP 395
Query: 428 NRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
N+W S L + ++M+ECWY N AARLTALRIKKT++ +
Sbjct: 396 NQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 435
>AC079750-1|AAX88951.1| 468|Homo sapiens unknown protein.
Length = 468
Score = 479 bits (1180), Expect = e-134
Identities = 224/400 (56%), Positives = 299/400 (74%), Gaps = 4/400 (1%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTATAWQVVPWI-MGLVVFAICVALSLWWAKKWRADGKR 130
CC +D+CN +P ++ I + + + +I L++W + + ++
Sbjct: 61 CCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRK 120
Query: 131 PPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGR 189
RP +E ++ L T++D+I ++T SGSGSGLPLLVQR+IAR I L +I+GKGR
Sbjct: 121 KKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGR 180
Query: 190 FGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 249
FGEVW GRW GE+VAVKIFSSR+E SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ
Sbjct: 181 FGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 240
Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309
LWL+++YHE GSL+D+L + +IK++LSIA+GLAHLHM+IVGT+GKPAIAHRD+K
Sbjct: 241 LWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 300
Query: 310 SKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDP 369
SKNILVK +C I DLGLAV+H+ +++D+P +VGTKRYMAPE+LD+TM+ F+
Sbjct: 301 SKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFES 360
Query: 370 YKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVP 427
+KR+D+YS GLV WE+ARRC G + ++YQ PYYD VP DP++E+MR+VVC +K RP++P
Sbjct: 361 FKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIP 420
Query: 428 NRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
N+W S L + ++M+ECWY N AARLTALRIKKT++ +
Sbjct: 421 NQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 460
>Z22534-1|CAA80256.1| 509|Homo sapiens ALK-2 protein.
Length = 509
Score = 477 bits (1176), Expect = e-134
Identities = 236/415 (56%), Positives = 302/415 (72%), Gaps = 11/415 (2%)
Query: 72 CCASDYCNRDIFAEFWIKETS-PTATAWQV-VPWIMGLVVFAICVALSLWWAKKWRADGK 129
CC D+CNR+I A+ K S P + + V I+ VVFA+C+ L + +
Sbjct: 93 CCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRR 152
Query: 130 RPPRPYPDEDETKHILNTPTT-----TIRDMIELT-TSGSGSGLPLLVQRSIARQIQLVD 183
R P + E I TT T+ D+++ + TSGSGSGLP LVQR++ARQI L++
Sbjct: 153 NQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLE 212
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+GKGR+GEVWRG W+GENVAVKIFSSR+E SWFRE E+Y TVMLRHENILGFIA+D
Sbjct: 213 CVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTS 272
Query: 244 NGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAI 303
+ TQLWLIT YHE GSL+D+L ++D+ + +++ LSIA+GLAHLH++I GT+GKPAI
Sbjct: 273 RHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAI 332
Query: 304 AHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMD 363
AHRDLKSKNILVK N C I DLGLAV H+ S + +DV + RVGTKRYMAPEVLDET+
Sbjct: 333 AHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQ 392
Query: 364 TRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVCTEK 421
FD YKR D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDMR+VVC ++
Sbjct: 393 VDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQ 452
Query: 422 RRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTNGADYIK 476
+RPN+PNRW SDP L+ ++K+MKECWYQNP+ARLTALRIKKTL + N D +K
Sbjct: 453 QRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI-DNSLDKLK 506
>L02911-1|AAA36614.1| 509|Homo sapiens serine kinase receptor
protein.
Length = 509
Score = 477 bits (1176), Expect = e-134
Identities = 236/415 (56%), Positives = 302/415 (72%), Gaps = 11/415 (2%)
Query: 72 CCASDYCNRDIFAEFWIKETS-PTATAWQV-VPWIMGLVVFAICVALSLWWAKKWRADGK 129
CC D+CNR+I A+ K S P + + V I+ VVFA+C+ L + +
Sbjct: 93 CCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRR 152
Query: 130 RPPRPYPDEDETKHILNTPTT-----TIRDMIELT-TSGSGSGLPLLVQRSIARQIQLVD 183
R P + E I TT T+ D+++ + TSGSGSGLP LVQR++ARQI L++
Sbjct: 153 NQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLE 212
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+GKGR+GEVWRG W+GENVAVKIFSSR+E SWFRE E+Y TVMLRHENILGFIA+D
Sbjct: 213 CVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTS 272
Query: 244 NGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAI 303
+ TQLWLIT YHE GSL+D+L ++D+ + +++ LSIA+GLAHLH++I GT+GKPAI
Sbjct: 273 RHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAI 332
Query: 304 AHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMD 363
AHRDLKSKNILVK N C I DLGLAV H+ S + +DV + RVGTKRYMAPEVLDET+
Sbjct: 333 AHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQ 392
Query: 364 TRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVCTEK 421
FD YKR D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDMR+VVC ++
Sbjct: 393 VDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQ 452
Query: 422 RRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTNGADYIK 476
+RPN+PNRW SDP L+ ++K+MKECWYQNP+ARLTALRIKKTL + N D +K
Sbjct: 453 QRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI-DNSLDKLK 506
>BC033867-1|AAH33867.1| 509|Homo sapiens ACVR1 protein protein.
Length = 509
Score = 477 bits (1176), Expect = e-134
Identities = 236/415 (56%), Positives = 302/415 (72%), Gaps = 11/415 (2%)
Query: 72 CCASDYCNRDIFAEFWIKETS-PTATAWQV-VPWIMGLVVFAICVALSLWWAKKWRADGK 129
CC D+CNR+I A+ K S P + + V I+ VVFA+C+ L + +
Sbjct: 93 CCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRR 152
Query: 130 RPPRPYPDEDETKHILNTPTT-----TIRDMIELT-TSGSGSGLPLLVQRSIARQIQLVD 183
R P + E I TT T+ D+++ + TSGSGSGLP LVQR++ARQI L++
Sbjct: 153 NQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLE 212
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+GKGR+GEVWRG W+GENVAVKIFSSR+E SWFRE E+Y TVMLRHENILGFIA+D
Sbjct: 213 CVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTS 272
Query: 244 NGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAI 303
+ TQLWLIT YHE GSL+D+L ++D+ + +++ LSIA+GLAHLH++I GT+GKPAI
Sbjct: 273 RHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAI 332
Query: 304 AHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMD 363
AHRDLKSKNILVK N C I DLGLAV H+ S + +DV + RVGTKRYMAPEVLDET+
Sbjct: 333 AHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQ 392
Query: 364 TRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVCTEK 421
FD YKR D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDMR+VVC ++
Sbjct: 393 VDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQ 452
Query: 422 RRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTNGADYIK 476
+RPN+PNRW SDP L+ ++K+MKECWYQNP+ARLTALRIKKTL + N D +K
Sbjct: 453 QRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKI-DNSLDKLK 506
>BC022530-1|AAH22530.1| 493|Homo sapiens activin A receptor, type
IC protein.
Length = 493
Score = 477 bits (1175), Expect = e-134
Identities = 223/400 (55%), Positives = 298/400 (74%), Gaps = 4/400 (1%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTATAWQVVPWI-MGLVVFAICVALSLWWAKKWRADGKR 130
CC +D+CN +P ++ I + + + +I L++W + + ++
Sbjct: 86 CCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRK 145
Query: 131 PPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGR 189
RP +E ++ L T++D+I ++T SGSGSGLPLLVQR+IAR I L +I+GKGR
Sbjct: 146 KKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGR 205
Query: 190 FGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 249
FGEVW GRW GE+VAVKIFSSR+E WFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ
Sbjct: 206 FGEVWHGRWCGEDVAVKIFSSRDERYWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQ 265
Query: 250 LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLK 309
LWL+++YHE GSL+D+L + +IK++LSIA+GLAHLHM+IVGT+GKPAIAHRD+K
Sbjct: 266 LWLVSEYHEQGSLYDYLNRNIVTMAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIK 325
Query: 310 SKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDP 369
SKNILVK +C I DLGLAV+H+ +++D+P +VGTKRYMAPE+LD+TM+ F+
Sbjct: 326 SKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFES 385
Query: 370 YKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVP 427
+KR+D+YS GLV WE+ARRC G + ++YQ PYYD VP DP++E+MR+VVC +K RP++P
Sbjct: 386 FKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIP 445
Query: 428 NRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
N+W S L + ++M+ECWY N AARLTALRIKKT++ +
Sbjct: 446 NQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 485
>BC071181-1|AAH71181.1| 426|Homo sapiens TGFBR1 protein protein.
Length = 426
Score = 469 bits (1155), Expect = e-131
Identities = 211/305 (69%), Positives = 259/305 (84%), Gaps = 2/305 (0%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQ 224
+GLPLLVQR+IAR I L + IGKGRFGEVWRG+WRGE VAVKIFSSREE SWFREAEIYQ
Sbjct: 114 TGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQ 173
Query: 225 TVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIA 284
TVMLRHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A
Sbjct: 174 TVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTA 233
Query: 285 TGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPST 344
+GLAHLHM+IVGT+GKPAIAHRDLKSKNILVK N +C I DLGLAVRH+ + D++D+
Sbjct: 234 SGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPN 293
Query: 345 NRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYD 402
+RVGTKRYMAPEVLD++++ + F+ +KR+D+Y+ GLV WE+ARRC G + +DYQ PYYD
Sbjct: 294 HRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYD 353
Query: 403 CVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKK 462
VP DP++E+MR+VVC +K RPN+PNRW S L ++K+M+ECWY N AARLTALRIKK
Sbjct: 354 LVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKK 413
Query: 463 TLANV 467
TL+ +
Sbjct: 414 TLSQL 418
>Z22535-1|CAA80257.1| 532|Homo sapiens ALK-3 protein.
Length = 532
Score = 458 bits (1130), Expect = e-128
Identities = 222/412 (53%), Positives = 288/412 (69%), Gaps = 17/412 (4%)
Query: 67 RSDIICCASDYCNRDIFAEFWIKETSPTATAWQV----VPWIMGLVVFAICVALSLWWAK 122
R I CC ++ CN+ +++ T P + W++ L+ A+C+ + ++
Sbjct: 119 RRTIECCRTNLCNQ------YLQPTLPPVVIGPFFDGSIRWLVLLISMAVCIIAMIIFSS 172
Query: 123 ----KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIAR 177
K R Y + E +++D+I+ + +SGSGSGLPLLVQR+IA+
Sbjct: 173 CFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAK 232
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFI 237
QIQ+V +GKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFI
Sbjct: 233 QIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFI 292
Query: 238 AADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGT 297
AAD K G+WTQL+LITDYHENGSL+DFL ++D+ L+K++ S A GL HLH +I GT
Sbjct: 293 AADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGT 352
Query: 298 KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
+GKPAIAHRDLKSKNIL+K N SC I DLGLAV+ N + VDVP RVGTKRYMAPEV
Sbjct: 353 QGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEV 412
Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRR 415
LDE+++ F PY +D+YSFGL++WEMARRC G + ++YQ PYY+ VP DP+ EDMR
Sbjct: 413 LDESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMRE 472
Query: 416 VVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
VVC ++ RP V NRW+SD L + K+M ECW NPA+RLTALRIKKTLA +
Sbjct: 473 VVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKM 524
>BC028383-1|AAH28383.1| 532|Homo sapiens bone morphogenetic protein
receptor, type IA protein.
Length = 532
Score = 458 bits (1130), Expect = e-128
Identities = 222/412 (53%), Positives = 288/412 (69%), Gaps = 17/412 (4%)
Query: 67 RSDIICCASDYCNRDIFAEFWIKETSPTATAWQV----VPWIMGLVVFAICVALSLWWAK 122
R I CC ++ CN+ +++ T P + W++ L+ A+C+ + ++
Sbjct: 119 RRTIECCRTNLCNQ------YLQPTLPPVVIGPFFDGSIRWLVLLISMAVCIIAMIIFSS 172
Query: 123 ----KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIAR 177
K R Y + E +++D+I+ + +SGSGSGLPLLVQR+IA+
Sbjct: 173 CFCYKHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAK 232
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFI 237
QIQ+V +GKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFI
Sbjct: 233 QIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFI 292
Query: 238 AADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGT 297
AAD K G+WTQL+LITDYHENGSL+DFL ++D+ L+K++ S A GL HLH +I GT
Sbjct: 293 AADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGT 352
Query: 298 KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
+GKPAIAHRDLKSKNIL+K N SC I DLGLAV+ N + VDVP RVGTKRYMAPEV
Sbjct: 353 QGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEV 412
Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRR 415
LDE+++ F PY +D+YSFGL++WEMARRC G + ++YQ PYY+ VP DP+ EDMR
Sbjct: 413 LDESLNKNHFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMRE 472
Query: 416 VVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
VVC ++ RP V NRW+SD L + K+M ECW NPA+RLTALRIKKTLA +
Sbjct: 473 VVCVKRLRPIVSNRWNSDECLRAVLKLMSECWAHNPASRLTALRIKKTLAKM 524
>AF525680-1|AAP21994.1| 413|Homo sapiens soluble activin
receptor-like kinase 7a protein.
Length = 413
Score = 448 bits (1105), Expect = e-125
Identities = 201/305 (65%), Positives = 254/305 (83%), Gaps = 2/305 (0%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQ 224
+GLPLLVQR+IAR I L +I+GKGRFGEVW GRW GE+VAVKIFSSR+E SWFREAEIYQ
Sbjct: 101 TGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQ 160
Query: 225 TVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIA 284
TVMLRHENILGFIAADNKDNGTWTQLWL+++YHE GSL+D+L + +IK++LSIA
Sbjct: 161 TVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIA 220
Query: 285 TGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPST 344
+GLAHLHM+IVGT+GKPAIAHRD+KSKNILVK +C I DLGLAV+H+ +++D+P
Sbjct: 221 SGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQN 280
Query: 345 NRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYD 402
+VGTKRYMAPE+LD+TM+ F+ +KR+D+YS GLV WE+ARRC G + ++YQ PYYD
Sbjct: 281 PKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYD 340
Query: 403 CVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKK 462
VP DP++E+MR+VVC +K RP++PN+W S L + ++M+ECWY N AARLTALRIKK
Sbjct: 341 MVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKK 400
Query: 463 TLANV 467
T++ +
Sbjct: 401 TISQL 405
>U89326-1|AAC28131.1| 502|Homo sapiens bone morphogenetic protein
receptor type I ALK-6 protein.
Length = 502
Score = 444 bits (1093), Expect = e-124
Identities = 215/408 (52%), Positives = 287/408 (70%), Gaps = 8/408 (1%)
Query: 66 ERSDIICCAS-DYCNRDIFAEFW-IKETSPTATAWQVVPWIMGLVVFAICVALSLWWAK- 122
+R I CC + CN+D+ +K ++ + V ++ + L + +
Sbjct: 89 QRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYF 148
Query: 123 KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIARQIQL 181
+++ RP E + +I P ++RD+IE + +SGSGSGLPLLVQR+IA+QIQ+
Sbjct: 149 RYKRQETRPRYSIGLEQDETYI--PPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQM 206
Query: 182 VDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241
V IGKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFIAAD
Sbjct: 207 VKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADI 266
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
K G+WTQL+LITDYHENGSL+D+L + ++D+ +++K++ S +GL HLH +I T+GKP
Sbjct: 267 KGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP 326
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
AIAHRDLKSKNILVK N +C I DLGLAV+ + VD+P RVGTKRYM PEVLDE+
Sbjct: 327 AIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDES 386
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCT 419
++ F Y +D+YSFGL+LWE+ARRC G + ++YQ PY+D VP DP+ EDMR +VC
Sbjct: 387 LNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCI 446
Query: 420 EKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
+K RP+ PNRW SD L + K+M ECW NPA+RLTALR+KKTLA +
Sbjct: 447 KKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKM 494
>D89675-1|BAA19765.1| 502|Homo sapiens bone morphogenetic protein
type IB receptor protein.
Length = 502
Score = 444 bits (1093), Expect = e-124
Identities = 215/408 (52%), Positives = 287/408 (70%), Gaps = 8/408 (1%)
Query: 66 ERSDIICCAS-DYCNRDIFAEFW-IKETSPTATAWQVVPWIMGLVVFAICVALSLWWAK- 122
+R I CC + CN+D+ +K ++ + V ++ + L + +
Sbjct: 89 QRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYF 148
Query: 123 KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIARQIQL 181
+++ RP E + +I P ++RD+IE + +SGSGSGLPLLVQR+IA+QIQ+
Sbjct: 149 RYKRQETRPRYSIGLEQDETYI--PPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQM 206
Query: 182 VDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241
V IGKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFIAAD
Sbjct: 207 VKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADI 266
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
K G+WTQL+LITDYHENGSL+D+L + ++D+ +++K++ S +GL HLH +I T+GKP
Sbjct: 267 KGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP 326
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
AIAHRDLKSKNILVK N +C I DLGLAV+ + VD+P RVGTKRYM PEVLDE+
Sbjct: 327 AIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDES 386
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCT 419
++ F Y +D+YSFGL+LWE+ARRC G + ++YQ PY+D VP DP+ EDMR +VC
Sbjct: 387 LNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCI 446
Query: 420 EKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
+K RP+ PNRW SD L + K+M ECW NPA+RLTALR+KKTLA +
Sbjct: 447 KKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKM 494
>BC069803-1|AAH69803.1| 502|Homo sapiens bone morphogenetic protein
receptor, type IB protein.
Length = 502
Score = 444 bits (1093), Expect = e-124
Identities = 215/408 (52%), Positives = 287/408 (70%), Gaps = 8/408 (1%)
Query: 66 ERSDIICCAS-DYCNRDIFAEFW-IKETSPTATAWQVVPWIMGLVVFAICVALSLWWAK- 122
+R I CC + CN+D+ +K ++ + V ++ + L + +
Sbjct: 89 QRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYF 148
Query: 123 KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIARQIQL 181
+++ RP E + +I P ++RD+IE + +SGSGSGLPLLVQR+IA+QIQ+
Sbjct: 149 RYKRQETRPRYSIGLEQDETYI--PPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQM 206
Query: 182 VDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241
V IGKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFIAAD
Sbjct: 207 VKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADI 266
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
K G+WTQL+LITDYHENGSL+D+L + ++D+ +++K++ S +GL HLH +I T+GKP
Sbjct: 267 KGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP 326
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
AIAHRDLKSKNILVK N +C I DLGLAV+ + VD+P RVGTKRYM PEVLDE+
Sbjct: 327 AIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDES 386
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCT 419
++ F Y +D+YSFGL+LWE+ARRC G + ++YQ PY+D VP DP+ EDMR +VC
Sbjct: 387 LNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCI 446
Query: 420 EKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
+K RP+ PNRW SD L + K+M ECW NPA+RLTALR+KKTLA +
Sbjct: 447 KKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKM 494
>BC069796-1|AAH69796.1| 502|Homo sapiens bone morphogenetic protein
receptor, type IB protein.
Length = 502
Score = 444 bits (1093), Expect = e-124
Identities = 215/408 (52%), Positives = 287/408 (70%), Gaps = 8/408 (1%)
Query: 66 ERSDIICCAS-DYCNRDIFAEFW-IKETSPTATAWQVVPWIMGLVVFAICVALSLWWAK- 122
+R I CC + CN+D+ +K ++ + V ++ + L + +
Sbjct: 89 QRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYF 148
Query: 123 KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIARQIQL 181
+++ RP E + +I P ++RD+IE + +SGSGSGLPLLVQR+IA+QIQ+
Sbjct: 149 RYKRQETRPRYSIGLEQDETYI--PPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQM 206
Query: 182 VDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241
V IGKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFIAAD
Sbjct: 207 VKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADI 266
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
K G+WTQL+LITDYHENGSL+D+L + ++D+ +++K++ S +GL HLH +I T+GKP
Sbjct: 267 KGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP 326
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
AIAHRDLKSKNILVK N +C I DLGLAV+ + VD+P RVGTKRYM PEVLDE+
Sbjct: 327 AIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDES 386
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCT 419
++ F Y +D+YSFGL+LWE+ARRC G + ++YQ PY+D VP DP+ EDMR +VC
Sbjct: 387 LNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCI 446
Query: 420 EKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
+K RP+ PNRW SD L + K+M ECW NPA+RLTALR+KKTLA +
Sbjct: 447 KKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKM 494
>BC047773-1|AAH47773.1| 502|Homo sapiens BMPR1B protein protein.
Length = 502
Score = 444 bits (1093), Expect = e-124
Identities = 215/408 (52%), Positives = 287/408 (70%), Gaps = 8/408 (1%)
Query: 66 ERSDIICCAS-DYCNRDIFAEFW-IKETSPTATAWQVVPWIMGLVVFAICVALSLWWAK- 122
+R I CC + CN+D+ +K ++ + V ++ + L + +
Sbjct: 89 QRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYF 148
Query: 123 KWRADGKRPPRPYPDEDETKHILNTPTTTIRDMIELT-TSGSGSGLPLLVQRSIARQIQL 181
+++ RP E + +I P ++RD+IE + +SGSGSGLPLLVQR+IA+QIQ+
Sbjct: 149 RYKRQETRPRYSIGLEQDETYI--PPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQM 206
Query: 182 VDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADN 241
V IGKGR+GEVW G+WRGE VAVK+F + EE SWFRE EIYQTV++RHENILGFIAAD
Sbjct: 207 VKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADI 266
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
K G+WTQL+LITDYHENGSL+D+L + ++D+ +++K++ S +GL HLH +I T+GKP
Sbjct: 267 KGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKP 326
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
AIAHRDLKSKNILVK N +C I DLGLAV+ + VD+P RVGTKRYM PEVLDE+
Sbjct: 327 AIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDES 386
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCT 419
++ F Y +D+YSFGL+LWE+ARRC G + ++YQ PY+D VP DP+ EDMR +VC
Sbjct: 387 LNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCI 446
Query: 420 EKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
+K RP+ PNRW SD L + K+M ECW NPA+RLTALR+KKTLA +
Sbjct: 447 KKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTLAKM 494
>L10125-1|AAA60555.1| 476|Homo sapiens activin type I receptor
protein.
Length = 476
Score = 441 bits (1087), Expect = e-123
Identities = 216/391 (55%), Positives = 277/391 (70%), Gaps = 8/391 (2%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEV GRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVMAGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPP 406
TKRYMAPEVLDET++ + FD +K +D+Y+ G+V WE+ARRC G + ++YQ PYYD VP
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGVVYWEIARRCNSGGVHEEYQLPYYDLVPS 436
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPVLS 437
DP++E+MR+VVC +K RPN+PN W S V S
Sbjct: 437 DPSIEEMRKVVCDQKLRPNIPNWWQSYEVRS 467
>Z22533-1|CAA80255.1| 503|Homo sapiens ALK-1 protein.
Length = 503
Score = 437 bits (1077), Expect = e-122
Identities = 212/412 (51%), Positives = 295/412 (71%), Gaps = 18/412 (4%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTA----TAWQ---VVPWIMGLVVFAICVALSLWWAKKW 124
CC S CN ++ ++ T P + T Q ++ ++ L+ L LW ++
Sbjct: 89 CCDSHLCNHNV--SLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRR- 145
Query: 125 RADGKRPPRPYPDEDETKHILNTPT---TTIRDMIELT-TSGSGSGLPLLVQRSIARQIQ 180
R + +R + + E+ IL T + D+++ T+GSGSGLP LVQR++ARQ+
Sbjct: 146 RQEKQRGL--HSELGESSLILKASEQGDTMLGDLLDSDCTTGSGSGLPFLVQRTVARQVA 203
Query: 181 LVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAAD 240
LV+ +GKGR+GEVWRG W GE+VAVKIFSSR+E SWFRE EIY TV+LRH+NILGFIA+D
Sbjct: 204 LVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASD 263
Query: 241 NKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
+ TQLWLIT YHE+GSL+DFL ++++ + +++++S A GLAHLH++I GT+GK
Sbjct: 264 MTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGK 323
Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360
PAIAHRD KS+N+LVKSNL C I DLGLAV H+ +D +D+ + RVGTKRYMAPEVLDE
Sbjct: 324 PAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDE 383
Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVC 418
+ T F+ YK +D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDM++VVC
Sbjct: 384 QIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVC 443
Query: 419 TEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
+++ P +PNR +DPVLSG++++M+ECWY NP+ARLTALRIKKTL + +
Sbjct: 444 VDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNS 495
>U77713-1|AAB61900.1| 503|Homo sapiens activin receptor like kinase
1 protein.
Length = 503
Score = 436 bits (1073), Expect = e-121
Identities = 211/412 (51%), Positives = 295/412 (71%), Gaps = 18/412 (4%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTA----TAWQ---VVPWIMGLVVFAICVALSLWWAKKW 124
CC S CN ++ ++ T P + T Q ++ ++ L+ L LW ++
Sbjct: 89 CCDSHLCNHNV--SLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRR- 145
Query: 125 RADGKRPPRPYPDEDETKHILNTPT---TTIRDMIELT-TSGSGSGLPLLVQRSIARQIQ 180
R + +R + + E+ IL + + D+++ T+GSGSGLP LVQR++ARQ+
Sbjct: 146 RQEKQRGL--HSELGESSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVA 203
Query: 181 LVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAAD 240
LV+ +GKGR+GEVWRG W GE+VAVKIFSSR+E SWFRE EIY TV+LRH+NILGFIA+D
Sbjct: 204 LVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASD 263
Query: 241 NKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
+ TQLWLIT YHE+GSL+DFL ++++ + +++++S A GLAHLH++I GT+GK
Sbjct: 264 MTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGK 323
Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360
PAIAHRD KS+N+LVKSNL C I DLGLAV H+ +D +D+ + RVGTKRYMAPEVLDE
Sbjct: 324 PAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDE 383
Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVC 418
+ T F+ YK +D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDM++VVC
Sbjct: 384 QIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVC 443
Query: 419 TEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
+++ P +PNR +DPVLSG++++M+ECWY NP+ARLTALRIKKTL + +
Sbjct: 444 VDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNS 495
>L17075-1|AAA16160.1| 503|Homo sapiens TGF-b superfamily receptor
type I protein.
Length = 503
Score = 436 bits (1073), Expect = e-121
Identities = 211/412 (51%), Positives = 295/412 (71%), Gaps = 18/412 (4%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTA----TAWQ---VVPWIMGLVVFAICVALSLWWAKKW 124
CC S CN ++ ++ T P + T Q ++ ++ L+ L LW ++
Sbjct: 89 CCDSHLCNHNV--SLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRR- 145
Query: 125 RADGKRPPRPYPDEDETKHILNTPT---TTIRDMIELT-TSGSGSGLPLLVQRSIARQIQ 180
R + +R + + E+ IL + + D+++ T+GSGSGLP LVQR++ARQ+
Sbjct: 146 RQEKQRGL--HSELGESSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVA 203
Query: 181 LVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAAD 240
LV+ +GKGR+GEVWRG W GE+VAVKIFSSR+E SWFRE EIY TV+LRH+NILGFIA+D
Sbjct: 204 LVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASD 263
Query: 241 NKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
+ TQLWLIT YHE+GSL+DFL ++++ + +++++S A GLAHLH++I GT+GK
Sbjct: 264 MTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGK 323
Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360
PAIAHRD KS+N+LVKSNL C I DLGLAV H+ +D +D+ + RVGTKRYMAPEVLDE
Sbjct: 324 PAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDE 383
Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVC 418
+ T F+ YK +D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDM++VVC
Sbjct: 384 QIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVC 443
Query: 419 TEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
+++ P +PNR +DPVLSG++++M+ECWY NP+ARLTALRIKKTL + +
Sbjct: 444 VDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNS 495
>BC042637-1|AAH42637.1| 503|Homo sapiens activin A receptor type
II-like 1 protein.
Length = 503
Score = 436 bits (1073), Expect = e-121
Identities = 211/412 (51%), Positives = 295/412 (71%), Gaps = 18/412 (4%)
Query: 72 CCASDYCNRDIFAEFWIKETSPTA----TAWQ---VVPWIMGLVVFAICVALSLWWAKKW 124
CC S CN ++ ++ T P + T Q ++ ++ L+ L LW ++
Sbjct: 89 CCDSHLCNHNV--SLVLEATQPPSEQPGTDGQLALILGPVLALLALVALGVLGLWHVRR- 145
Query: 125 RADGKRPPRPYPDEDETKHILNTPT---TTIRDMIELT-TSGSGSGLPLLVQRSIARQIQ 180
R + +R + + E+ IL + + D+++ T+GSGSGLP LVQR++ARQ+
Sbjct: 146 RQEKQRGL--HSELGESSLILKASEQGDSMLGDLLDSDCTTGSGSGLPFLVQRTVARQVA 203
Query: 181 LVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAAD 240
LV+ +GKGR+GEVWRG W GE+VAVKIFSSR+E SWFRE EIY TV+LRH+NILGFIA+D
Sbjct: 204 LVECVGKGRYGEVWRGLWHGESVAVKIFSSRDEQSWFRETEIYNTVLLRHDNILGFIASD 263
Query: 241 NKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
+ TQLWLIT YHE+GSL+DFL ++++ + +++++S A GLAHLH++I GT+GK
Sbjct: 264 MTSRNSSTQLWLITHYHEHGSLYDFLQRQTLEPHLALRLAVSAACGLAHLHVEIFGTQGK 323
Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360
PAIAHRD KS+N+LVKSNL C I DLGLAV H+ +D +D+ + RVGTKRYMAPEVLDE
Sbjct: 324 PAIAHRDFKSRNVLVKSNLQCCIADLGLAVMHSQGSDYLDIGNNPRVGTKRYMAPEVLDE 383
Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEMARR--CGNMPDDYQPPYYDCVPPDPALEDMRRVVC 418
+ T F+ YK +D+++FGLVLWE+ARR + +DY+PP+YD VP DP+ EDM++VVC
Sbjct: 384 QIRTDCFESYKWTDIWAFGLVLWEIARRTIVNGIVEDYRPPFYDVVPNDPSFEDMKKVVC 443
Query: 419 TEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
+++ P +PNR +DPVLSG++++M+ECWY NP+ARLTALRIKKTL + +
Sbjct: 444 VDQQTPTIPNRLAADPVLSGLAQMMRECWYPNPSARLTALRIKKTLQKISNS 495
>L10126-1|AAA60556.1| 487|Homo sapiens activin type I receptor
protein.
Length = 487
Score = 383 bits (943), Expect = e-106
Identities = 189/343 (55%), Positives = 242/343 (70%), Gaps = 6/343 (1%)
Query: 55 PGDKPVWCREDER-SDIICCASDYCNR-DIFAEFWIKETSPTATAW---QVVPWIMGLVV 109
P KP +C E + CC +DYCNR D+ + + W ++V I G V
Sbjct: 77 PAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPSMWGPVELVGIIAGPVF 136
Query: 110 FAICVALSLWWAKKWRADGKRPPRPYPDEDETKHILNTPTTTIRDMI-ELTTSGSGSGLP 168
+ + ++ + + ED + + + T++D++ +L+TSGSGSGLP
Sbjct: 137 LLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQDLVYDLSTSGSGSGLP 196
Query: 169 LLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVML 228
L VQR++AR I L +IIGKGRFGEV GRWRG +VAVKIFSSREE SWFREAEIYQTVML
Sbjct: 197 LFVQRTVARTIVLQEIIGKGRFGEVMAGRWRGGDVAVKIFSSREERSWFREAEIYQTVML 256
Query: 229 RHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLA 288
RHENILGFIAADNKDNGTWTQLWL++DYHE+GSLFD+L ++ +IK++LS A+GLA
Sbjct: 257 RHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTIEGMIKLALSAASGLA 316
Query: 289 HLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG 348
HLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+ D++D+ RVG
Sbjct: 317 HLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAVTDTIDIAPNQRVG 376
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGN 391
TKRYMAPEVLDET++ + FD +K +D+Y+ G+V WE+ARRC +
Sbjct: 377 TKRYMAPEVLDETINMKHFDSFKCADIYALGVVYWEIARRCNS 419
>AF525681-1|AAP21995.1| 336|Homo sapiens soluble activin
receptor-like kinase 7b protein.
Length = 336
Score = 311 bits (763), Expect = 4e-84
Identities = 135/227 (59%), Positives = 182/227 (80%), Gaps = 2/227 (0%)
Query: 243 DNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPA 302
DNGTWTQLWL+++YHE GSL+D+L + +IK++LSIA+GLAHLHM+IVGT+GKPA
Sbjct: 102 DNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPA 161
Query: 303 IAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETM 362
IAHRD+KSKNILVK +C I DLGLAV+H+ +++D+P +VGTKRYMAPE+LD+TM
Sbjct: 162 IAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTM 221
Query: 363 DTRQFDPYKRSDVYSFGLVLWEMARRC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTE 420
+ F+ +KR+D+YS GLV WE+ARRC G + ++YQ PYYD VP DP++E+MR+VVC +
Sbjct: 222 NVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQ 281
Query: 421 KRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANV 467
K RP++PN+W S L + ++M+ECWY N AARLTALRIKKT++ +
Sbjct: 282 KFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQL 328
>AC013731-1|AAY24272.1| 355|Homo sapiens unknown protein.
Length = 355
Score = 273 bits (669), Expect = 1e-72
Identities = 143/263 (54%), Positives = 183/263 (69%), Gaps = 8/263 (3%)
Query: 72 CCASDYCNRDIFAEFWIKETS-PTATAWQV-VPWIMGLVVFAICVALSLWWAKKWRADGK 129
CC D+CNR+I A+ K S P + + V I+ VVFA+C+ L + +
Sbjct: 93 CCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRR 152
Query: 130 RPPRPYPDEDETKHILNTPTT-----TIRDMIELT-TSGSGSGLPLLVQRSIARQIQLVD 183
R P + E I TT T+ D+++ + TSGSGSGLP LVQR++ARQI L++
Sbjct: 153 NQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLE 212
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+GKGR+GEVWRG W+GENVAVKIFSSR+E SWFRE E+Y TVMLRHENILGFIA+D
Sbjct: 213 CVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTS 272
Query: 244 NGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAI 303
+ TQLWLIT YHE GSL+D+L ++D+ + +++ LSIA+GLAHLH++I GT+GKPAI
Sbjct: 273 RHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAI 332
Query: 304 AHRDLKSKNILVKSNLSCVIGDL 326
AHRDLKSKNILVK N C I DL
Sbjct: 333 AHRDLKSKNILVKKNGQCCIADL 355
>L31848-1|AAA53351.1| 212|Homo sapiens activin type I receptor
SKR2-1 protein.
Length = 212
Score = 270 bits (661), Expect = 9e-72
Identities = 121/194 (62%), Positives = 154/194 (79%), Gaps = 2/194 (1%)
Query: 276 LIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVS 335
+IK++LS A+GLAHLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+
Sbjct: 11 MIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAV 70
Query: 336 NDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP 393
D++D+ RVGTKRYMAPEVLDET++ + FD +K +D+Y+ G+V WE+ARRC G +
Sbjct: 71 TDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGVVYWEIARRCNSGGVH 130
Query: 394 DDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAA 453
++YQ PYYD VP DP++E+MR+VVC +K RPN+PN W S L + K+M+ECWY N AA
Sbjct: 131 EEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYANGAA 190
Query: 454 RLTALRIKKTLANV 467
RLTALRIKKTL+ +
Sbjct: 191 RLTALRIKKTLSQL 204
>X63128-1|CAA44839.1| 513|Homo sapiens activin receptor protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>X62381-1|CAA44245.1| 513|Homo sapiens activin receptor protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>M93415-1|AAA35504.1| 513|Homo sapiens activin type II receptor
protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>BC069707-1|AAH69707.1| 513|Homo sapiens activin A receptor, type
IIA, precursor protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>BC067418-1|AAH67418.1| 513|Homo sapiens activin A receptor, type
IIA, precursor protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>BC067417-1|AAH67417.1| 513|Homo sapiens activin A receptor, type
IIA protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>AC009480-2|AAX93050.1| 513|Homo sapiens unknown protein.
Length = 513
Score = 237 bits (581), Expect = 5e-62
Identities = 122/286 (42%), Positives = 183/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRFG VW+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>D31770-1|BAA06548.1| 513|Homo sapiens activin typeII A receptor
precursor protein.
Length = 513
Score = 233 bits (571), Expect = 8e-61
Identities = 120/286 (41%), Positives = 182/286 (63%), Gaps = 8/286 (2%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL+++ +GRF +W+ + E VAVKIF +++ SW E E+Y ++HENIL F
Sbjct: 190 KPLQLLEVKARGRFPSLWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
I A+ + LWLIT +HE GSL DFL A + N L ++ ++A GLA+LH DI G
Sbjct: 250 IGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPG 309
Query: 297 TKG--KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMA 354
K KPAI+HRD+KSKN+L+K+NL+ I D GLA++ + D + +VGT+RYMA
Sbjct: 310 LKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFVAGKSAGD--THGQVGTRRYMA 367
Query: 355 PEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALE 411
PEVL+ ++ Q D + R D+Y+ GLVLWE+A RC + P D+Y P+ + + P+LE
Sbjct: 368 PEVLEGAINF-QRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLE 426
Query: 412 DMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
DM+ VV +K+RP + + W ++ + + ++ECW + ARL+A
Sbjct: 427 DMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSA 472
>X77533-1|CAA54671.1| 512|Homo sapiens activin type II receptor
protein.
Length = 512
Score = 230 bits (563), Expect = 7e-60
Identities = 118/287 (41%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ECW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA 471
>BC099642-1|AAH99642.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 230 bits (563), Expect = 7e-60
Identities = 118/287 (41%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ECW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA 471
>BC096244-1|AAH96244.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 230 bits (563), Expect = 7e-60
Identities = 118/287 (41%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ECW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA 471
>BC096243-1|AAH96243.1| 512|Homo sapiens activin A receptor, type
IIB protein.
Length = 512
Score = 230 bits (563), Expect = 7e-60
Identities = 118/287 (41%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ECW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA 471
>AB209449-1|BAD92686.1| 514|Homo sapiens activin A type IIB
receptor precursor variant protein.
Length = 514
Score = 230 bits (563), Expect = 7e-60
Identities = 118/287 (41%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 190 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 249
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 250 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 309
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 310 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 367
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 368 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 426
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ECW + ARL+A
Sbjct: 427 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSA 473
>AB008681-1|BAA24180.2| 512|Homo sapiens activin receptor type IIB
protein.
Length = 512
Score = 229 bits (560), Expect = 2e-59
Identities = 117/287 (40%), Positives = 183/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + +++CW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEDCWDHDAEARLSA 471
>DQ377559-1|ABG65632.1| 567|Homo sapiens transforming growth factor
beta receptor II protein.
Length = 567
Score = 229 bits (559), Expect = 2e-59
Identities = 117/288 (40%), Positives = 173/288 (60%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDLKS NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>AY675319-1|AAT70724.1| 567|Homo sapiens transforming growth
factor, beta receptor II (70/80kDa) protein.
Length = 567
Score = 229 bits (559), Expect = 2e-59
Identities = 117/288 (40%), Positives = 173/288 (60%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDLKS NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>U69152-1|AAB40916.1| 567|Homo sapiens transforming growth
factor-beta type II receptor protein.
Length = 567
Score = 228 bits (558), Expect = 3e-59
Identities = 117/288 (40%), Positives = 173/288 (60%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDLKS NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENAESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>U52246-1|AAB17553.1| 567|Homo sapiens transforming growth
factor-beta type II receptor protein.
Length = 567
Score = 228 bits (558), Expect = 3e-59
Identities = 117/288 (40%), Positives = 173/288 (60%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDLKS NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENAESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>M85079-1|AAA61164.1| 567|Homo sapiens TGF-beta type II receptor
protein.
Length = 567
Score = 228 bits (558), Expect = 3e-59
Identities = 117/288 (40%), Positives = 173/288 (60%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDLKS NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENAESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>L31848-2|AAA53350.1| 183|Homo sapiens activin type I receptor
SKR2-2 protein.
Length = 183
Score = 228 bits (558), Expect = 3e-59
Identities = 102/164 (62%), Positives = 130/164 (79%), Gaps = 2/164 (1%)
Query: 276 LIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVS 335
+IK++LS A+GLAHLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+
Sbjct: 11 MIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAV 70
Query: 336 NDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP 393
D++D+ RVGTKRYMAPEVLDET++ + FD +K +D+Y+ G+V WE+ARRC G +
Sbjct: 71 TDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGVVYWEIARRCNSGGVH 130
Query: 394 DDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLS 437
++YQ PYYD VP DP++E+MR+VVC +K RPN+PN W S V S
Sbjct: 131 EEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEVRS 174
>AF060202-1|AAC64515.1| 512|Homo sapiens activin receptor type IIB
protein.
Length = 512
Score = 228 bits (557), Expect = 4e-59
Identities = 117/287 (40%), Positives = 182/287 (63%), Gaps = 9/287 (3%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+ +QL++I +GRFG VW+ + + VAVKIF +++ SW E EI+ T ++HEN+L F
Sbjct: 188 KPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQF 247
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVG 296
IAA+ + + +LWLIT +H+ GSL D+L I N L ++ +++ GL++LH D+
Sbjct: 248 IAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPW 307
Query: 297 TKG---KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+G KP+IAHRD KSKN+L+KS+L+ V+ D GLAVR D + +VGT+RYM
Sbjct: 308 CRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGD--THGQVGTRRYM 365
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRC--GNMP-DDYQPPYYDCVPPDPAL 410
APEVL+ ++ Q D + R D+Y+ GLVLWE+ RC + P D+Y P+ + + P+L
Sbjct: 366 APEVLEGAINF-QRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSL 424
Query: 411 EDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
E+++ VV +K RP + + W P L+ + ++ CW + ARL+A
Sbjct: 425 EELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEACWDHDAEARLSA 471
>D50683-1|BAA09332.1| 567|Homo sapiens TGF-betaIIR alpha protein.
Length = 567
Score = 226 bits (553), Expect = 1e-58
Identities = 116/288 (40%), Positives = 172/288 (59%), Gaps = 9/288 (3%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRG------ENVAVKIFSSREECSWFREAEIYQTVMLRHEN 232
I+L ++GKGRF EV++ + + E VAVKIF E SW E +I+ + L+HEN
Sbjct: 244 IELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHEN 303
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
IL F+ A+ + Q WLIT +H G+L ++LT I L K+ S+A G+AHLH
Sbjct: 304 ILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHS 363
Query: 293 DIVGT-KGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
D + K I HRDL S NILVK++L+C + D GL++R + + D+ ++ +VGT R
Sbjct: 364 DHTPCGRPKMPIVHRDLNSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTAR 423
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPD--DYQPPYYDCVPPDPA 409
YMAPEVL+ M+ + +K++DVYS LVLWEM RC + + DY+PP+ V P
Sbjct: 424 YMAPEVLESRMNLENAESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPC 483
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTA 457
+E M+ V ++ RP +P+ W + + + + + ECW +P ARLTA
Sbjct: 484 VESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTA 531
>BC096245-1|AAH96245.1| 303|Homo sapiens ACVR2B protein protein.
Length = 303
Score = 210 bits (512), Expect = 1e-53
Identities = 109/261 (41%), Positives = 166/261 (63%), Gaps = 9/261 (3%)
Query: 203 VAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSL 262
VAVKIF +++ SW E EI+ T ++HEN+L FIAA+ + + +LWLIT +H+ GSL
Sbjct: 5 VAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSL 64
Query: 263 FDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKG---KPAIAHRDLKSKNILVKSNL 319
D+L I N L ++ +++ GL++LH D+ +G KP+IAHRD KSKN+L+KS+L
Sbjct: 65 TDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDL 124
Query: 320 SCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFG 379
+ V+ D GLAVR D + +VGT+RYMAPEVL+ ++ Q D + R D+Y+ G
Sbjct: 125 TAVLADFGLAVRFEPGKPPGD--THGQVGTRRYMAPEVLEGAINF-QRDAFLRIDMYAMG 181
Query: 380 LVLWEMARRC--GNMP-DDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVL 436
LVLWE+ RC + P D+Y P+ + + P+LE+++ VV +K RP + + W P L
Sbjct: 182 LVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGL 241
Query: 437 SGISKVMKECWYQNPAARLTA 457
+ + ++ECW + ARL+A
Sbjct: 242 AQLCVTIEECWDHDAEARLSA 262
>AC019186-2|AAY15094.1| 153|Homo sapiens unknown protein.
Length = 153
Score = 205 bits (501), Expect = 2e-52
Identities = 92/151 (60%), Positives = 118/151 (78%), Gaps = 3/151 (1%)
Query: 328 LAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMAR 387
LAV H+ S + +DV + RVGTKRYMAPEVLDET+ FD YKR D+++FGLVLWE+AR
Sbjct: 1 LAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVAR 60
Query: 388 RC--GNMPDDYQPPYYDCVPPDPALEDMRRVVCTEKRRPNVPNRWHSDPVLSGISKVMKE 445
R + +DY+PP+YD VP DP+ EDMR+VVC +++RPN+PNRW SDP L+ ++K+MKE
Sbjct: 61 RMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKE 120
Query: 446 CWYQNPAARLTALRIKKTLANVGTNGADYIK 476
CWYQNP+ARLTALRIKKTL + N D +K
Sbjct: 121 CWYQNPSARLTALRIKKTLTKI-DNSLDKLK 150
>Z48923-1|CAA88759.1| 1038|Homo sapiens BMPR-II precursor protein.
Length = 1038
Score = 190 bits (462), Expect = 1e-47
Identities = 105/302 (34%), Positives = 174/302 (57%), Gaps = 13/302 (4%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 203 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 262
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV-G 296
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++ G
Sbjct: 263 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG 322
Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRY 352
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RY
Sbjct: 323 DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY 382
Query: 353 MAPEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPP 406
MAPEVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V
Sbjct: 383 MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGN 442
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLA 465
P EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A
Sbjct: 443 HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMA 502
Query: 466 NV 467
+
Sbjct: 503 EL 504
>U25110-1|AAA86519.1| 530|Homo sapiens bone morphogenic protein
type II receptor protein.
Length = 530
Score = 190 bits (462), Expect = 1e-47
Identities = 105/302 (34%), Positives = 174/302 (57%), Gaps = 13/302 (4%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 203 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 262
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV-G 296
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++ G
Sbjct: 263 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG 322
Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRY 352
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RY
Sbjct: 323 DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY 382
Query: 353 MAPEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPP 406
MAPEVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V
Sbjct: 383 MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGN 442
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLA 465
P EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A
Sbjct: 443 HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMA 502
Query: 466 NV 467
+
Sbjct: 503 EL 504
>U20165-1|AAC50105.1| 1038|Homo sapiens type II serine/threonine
kinase receptor protein.
Length = 1038
Score = 190 bits (462), Expect = 1e-47
Identities = 105/302 (34%), Positives = 174/302 (57%), Gaps = 13/302 (4%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 203 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 262
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV-G 296
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++ G
Sbjct: 263 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG 322
Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRY 352
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RY
Sbjct: 323 DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY 382
Query: 353 MAPEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPP 406
MAPEVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V
Sbjct: 383 MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGN 442
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLA 465
P EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A
Sbjct: 443 HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMA 502
Query: 466 NV 467
+
Sbjct: 503 EL 504
>D50516-1|BAA09094.1| 1038|Homo sapiens type II receptor for bone
morphogenetic protein-4 protein.
Length = 1038
Score = 190 bits (462), Expect = 1e-47
Identities = 105/302 (34%), Positives = 174/302 (57%), Gaps = 13/302 (4%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 203 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 262
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV-G 296
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++ G
Sbjct: 263 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG 322
Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRY 352
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RY
Sbjct: 323 DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY 382
Query: 353 MAPEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPP 406
MAPEVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V
Sbjct: 383 MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGN 442
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLA 465
P EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A
Sbjct: 443 HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMA 502
Query: 466 NV 467
+
Sbjct: 503 EL 504
>BC052985-1|AAH52985.1| 1038|Homo sapiens bone morphogenetic protein
receptor, type II (serine/threonine kinase) protein.
Length = 1038
Score = 190 bits (462), Expect = 1e-47
Identities = 105/302 (34%), Positives = 174/302 (57%), Gaps = 13/302 (4%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 203 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 262
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDIV-G 296
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++ G
Sbjct: 263 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTELPRG 322
Query: 297 TKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRY 352
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RY
Sbjct: 323 DHYKPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRY 382
Query: 353 MAPEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPP 406
MAPEVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V
Sbjct: 383 MAPEVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGN 442
Query: 407 DPALEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLA 465
P EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A
Sbjct: 443 HPTFEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMA 502
Query: 466 NV 467
+
Sbjct: 503 EL 504
>X91156-1|CAA62593.1| 573|Homo sapiens antimullerian hormone type
II receptor protein.
Length = 573
Score = 177 bits (432), Expect = 5e-44
Identities = 106/301 (35%), Positives = 173/301 (57%), Gaps = 21/301 (6%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSNDSVDVPSTNR-------VGTKRYM 353
IAHRDL S+N+L++ + SC IGDLGLA V ++ P+ + GT+RYM
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYM 387
Query: 354 APEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRCGNM-PDDYQPPY---YDC-VPPD 407
APE+LD+T+D + + +R+D+YS L+LWE+ RC ++ PD PP+ Y+ +
Sbjct: 388 APELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNT 447
Query: 408 PALEDMRRVVCTEKRRPNVPNRWH---SDPVLSGISKVMKECWYQNPAARLTALRIKKTL 464
P +++ + E+RRP +P+ W +DP G+ +++++CW +P ARLTA +++ L
Sbjct: 448 PTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRL 505
Query: 465 A 465
A
Sbjct: 506 A 506
>X89013-1|CAA61418.1| 573|Homo sapiens anti-mullerian hormone type
II receptor protein.
Length = 573
Score = 177 bits (432), Expect = 5e-44
Identities = 106/301 (35%), Positives = 173/301 (57%), Gaps = 21/301 (6%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSNDSVDVPSTNR-------VGTKRYM 353
IAHRDL S+N+L++ + SC IGDLGLA V ++ P+ + GT+RYM
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYM 387
Query: 354 APEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRCGNM-PDDYQPPY---YDC-VPPD 407
APE+LD+T+D + + +R+D+YS L+LWE+ RC ++ PD PP+ Y+ +
Sbjct: 388 APELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNT 447
Query: 408 PALEDMRRVVCTEKRRPNVPNRWH---SDPVLSGISKVMKECWYQNPAARLTALRIKKTL 464
P +++ + E+RRP +P+ W +DP G+ +++++CW +P ARLTA +++ L
Sbjct: 448 PTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRL 505
Query: 465 A 465
A
Sbjct: 506 A 506
>U29700-1|AAC50328.1| 573|Homo sapiens anti-mullerian hormone type
II receptor precursor protein.
Length = 573
Score = 177 bits (432), Expect = 5e-44
Identities = 106/301 (35%), Positives = 173/301 (57%), Gaps = 21/301 (6%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSNDSVDVPSTNR-------VGTKRYM 353
IAHRDL S+N+L++ + SC IGDLGLA V ++ P+ + GT+RYM
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYM 387
Query: 354 APEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRCGNM-PDDYQPPY---YDC-VPPD 407
APE+LD+T+D + + +R+D+YS L+LWE+ RC ++ PD PP+ Y+ +
Sbjct: 388 APELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNT 447
Query: 408 PALEDMRRVVCTEKRRPNVPNRWH---SDPVLSGISKVMKECWYQNPAARLTALRIKKTL 464
P +++ + E+RRP +P+ W +DP G+ +++++CW +P ARLTA +++ L
Sbjct: 448 PTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRL 505
Query: 465 A 465
A
Sbjct: 506 A 506
>BC126316-1|AAI26317.1| 573|Homo sapiens anti-Mullerian hormone
receptor, type II protein.
Length = 573
Score = 177 bits (432), Expect = 5e-44
Identities = 106/301 (35%), Positives = 173/301 (57%), Gaps = 21/301 (6%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSNDSVDVPSTNR-------VGTKRYM 353
IAHRDL S+N+L++ + SC IGDLGLA V ++ P+ + GT+RYM
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYM 387
Query: 354 APEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRCGNM-PDDYQPPY---YDC-VPPD 407
APE+LD+T+D + + +R+D+YS L+LWE+ RC ++ PD PP+ Y+ +
Sbjct: 388 APELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNT 447
Query: 408 PALEDMRRVVCTEKRRPNVPNRWH---SDPVLSGISKVMKECWYQNPAARLTALRIKKTL 464
P +++ + E+RRP +P+ W +DP G+ +++++CW +P ARLTA +++ L
Sbjct: 448 PTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRL 505
Query: 465 A 465
A
Sbjct: 506 A 506
>AF172932-1|AAD48497.1| 573|Homo sapiens MIS type II receptor
protein.
Length = 573
Score = 177 bits (432), Expect = 5e-44
Identities = 106/301 (35%), Positives = 173/301 (57%), Gaps = 21/301 (6%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLA-VRHNVSNDSVDVPSTNR-------VGTKRYM 353
IAHRDL S+N+L++ + SC IGDLGLA V ++ P+ + GT+RYM
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYM 387
Query: 354 APEVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRCGNM-PDDYQPPY---YDC-VPPD 407
APE+LD+T+D + + +R+D+YS L+LWE+ RC ++ PD PP+ Y+ +
Sbjct: 388 APELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNT 447
Query: 408 PALEDMRRVVCTEKRRPNVPNRWH---SDPVLSGISKVMKECWYQNPAARLTALRIKKTL 464
P +++ + E+RRP +P+ W +DP G+ +++++CW +P ARLTA +++ L
Sbjct: 448 PTSDELWALAVQERRRPYIPSTWRCFATDP--DGLRELLEDCWDADPEARLTAECVQQRL 505
Query: 465 A 465
A
Sbjct: 506 A 506
>L31848-3|AAA53349.1| 194|Homo sapiens activin type I receptor
SKR2-3 protein.
Length = 194
Score = 170 bits (414), Expect = 8e-42
Identities = 75/116 (64%), Positives = 95/116 (81%)
Query: 276 LIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVS 335
+IK++LS A+GLAHLHM+IVGT+GKP IAHRDLKSKNILVK N C I DLGLAVRH+
Sbjct: 11 MIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHDAV 70
Query: 336 NDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGN 391
D++D+ RVGTKRYMAPEVLDET++ + FD +K +D+Y+ G+V WE+ARRC +
Sbjct: 71 TDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGVVYWEIARRCNS 126
>AC009960-1|AAX76517.1| 715|Homo sapiens unknown protein.
Length = 715
Score = 121 bits (291), Expect = 6e-27
Identities = 67/179 (37%), Positives = 104/179 (58%), Gaps = 11/179 (6%)
Query: 300 KPAIAHRDLKSKNILVKSNLSCVIGDLGLAVR----HNVSNDSVDVPSTNRVGTKRYMAP 355
KPAI+HRDL S+N+LVK++ +CVI D GL++R V D + + VGT RYMAP
Sbjct: 3 KPAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAP 62
Query: 356 EVLDETMDTRQFD-PYKRSDVYSFGLVLWEMARRC-----GNMPDDYQPPYYDCVPPDPA 409
EVL+ ++ R + K+ D+Y+ GL+ WE+ RC G +YQ + V P
Sbjct: 63 EVLEGAVNLRDCESALKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPT 122
Query: 410 LEDMRRVVCTEKRRPNVPNRWHSDPV-LSGISKVMKECWYQNPAARLTALRIKKTLANV 467
EDM+ +V EK+RP P W + + + + + +++CW Q+ ARLTA ++ +A +
Sbjct: 123 FEDMQVLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEERMAEL 181
>AY714878-1|AAU21221.1| 478|Homo sapiens anti-Mullerian hormone
receptor type II protein.
Length = 478
Score = 103 bits (246), Expect = 2e-21
Identities = 57/149 (38%), Positives = 87/149 (58%), Gaps = 2/149 (1%)
Query: 184 IIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+I +G VW G+ +G+ VA+K F R + E +Y+ L+H++I+ FI A
Sbjct: 208 VIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGG 267
Query: 244 NGTWTQ-LWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI-VGTKGKP 301
G L+ + H GSL +LT + D + ++M+LS+A GLA LH + + KP
Sbjct: 268 PGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEEHWQNGQYKP 327
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAV 330
IAHRDL S+N+L++ + SC IGDLGLA+
Sbjct: 328 GIAHRDLSSQNVLIREDGSCAIGDLGLAL 356
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 97.1 bits (231), Expect = 1e-19
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 46/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLP-------VKWT 353
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 354 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 397
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 398 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 446
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 93.9 bits (223), Expect = 1e-18
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 47/297 (15%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++++L+ IGKG FG+V G +RG VAVK + F AE LRH N++
Sbjct: 193 KELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFL-AEASVMTQLRHSNLVQL 251
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMD 293
+ ++ G L+++T+Y GSL D+L ++ + + L+K SL + + +L
Sbjct: 252 LGVIVEEKG---GLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLE-- 306
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
G HRDL ++N+LV + + D GL + + D+ +P ++
Sbjct: 307 --GNN----FVHRDLAARNVLVSEDNVAKVSDFGL-TKEASTQDTGKLP-------VKWT 352
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPYYDCVPPDPALEDM 413
APE L E ++F +SDV+SFG++LWE+ G +P + P D VP
Sbjct: 353 APEALRE----KKFS--TKSDVWSFGILLWEI-YSFGRVPYP-RIPLKDVVP-------- 396
Query: 414 RRVVCTEKRRPNVPNRWHSDPVLSGISKVMKECWYQNPAARLTALRIKKTLANVGTN 470
RV + + + P D + +VMK CW+ + A R + L++++ L ++ T+
Sbjct: 397 -RV--EKGYKMDAP-----DGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHIKTH 445
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 90.6 bits (215), Expect = 1e-17
Identities = 75/216 (34%), Positives = 107/216 (49%), Gaps = 26/216 (12%)
Query: 176 ARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHE 231
A ++ L IG G FG V++G+W G+ VAVKI + E+ FR E+ RH
Sbjct: 346 ASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRN-EVAVLRKTRHV 403
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGLAH 289
NIL F+ KDN L ++T + E SL+ L + LI ++ A G+ +
Sbjct: 404 NILLFMGYMTKDN-----LAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LH I HRD+KS NI + L+ IGD GLA + + S V G+
Sbjct: 459 LHAK--------NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP--TGS 508
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ D F +SDVYS+G+VL+E+
Sbjct: 509 VLWMAPEVI-RMQDNNPFS--FQSDVYSYGIVLYEL 541
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 90.6 bits (215), Expect = 1e-17
Identities = 75/216 (34%), Positives = 107/216 (49%), Gaps = 26/216 (12%)
Query: 176 ARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHE 231
A ++ L IG G FG V++G+W G+ VAVKI + E+ FR E+ RH
Sbjct: 119 ASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRN-EVAVLRKTRHV 176
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGLAH 289
NIL F+ KDN L ++T + E SL+ L + LI ++ A G+ +
Sbjct: 177 NILLFMGYMTKDN-----LAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 231
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LH I HRD+KS NI + L+ IGD GLA + + S V G+
Sbjct: 232 LHAK--------NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP--TGS 281
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ D F +SDVYS+G+VL+E+
Sbjct: 282 VLWMAPEVI-RMQDNNPFS--FQSDVYSYGIVLYEL 314
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 90.6 bits (215), Expect = 1e-17
Identities = 75/216 (34%), Positives = 107/216 (49%), Gaps = 26/216 (12%)
Query: 176 ARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHE 231
A ++ L IG G FG V++G+W G+ VAVKI + E+ FR E+ RH
Sbjct: 346 ASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRN-EVAVLRKTRHV 403
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGLAH 289
NIL F+ KDN L ++T + E SL+ L + LI ++ A G+ +
Sbjct: 404 NILLFMGYMTKDN-----LAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LH I HRD+KS NI + L+ IGD GLA + + S V G+
Sbjct: 459 LHAK--------NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP--TGS 508
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ D F +SDVYS+G+VL+E+
Sbjct: 509 VLWMAPEVI-RMQDNNPFS--FQSDVYSYGIVLYEL 541
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 90.6 bits (215), Expect = 1e-17
Identities = 75/216 (34%), Positives = 107/216 (49%), Gaps = 26/216 (12%)
Query: 176 ARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHE 231
A ++ L IG G FG V++G+W G+ VAVKI + E+ FR E+ RH
Sbjct: 346 ASEVMLSTRIGSGSFGTVYKGKWHGD-VAVKILKVVDPTPEQFQAFRN-EVAVLRKTRHV 403
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGLAH 289
NIL F+ KDN L ++T + E SL+ L + LI ++ A G+ +
Sbjct: 404 NILLFMGYMTKDN-----LAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDY 458
Query: 290 LHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGT 349
LH I HRD+KS NI + L+ IGD GLA + + S V G+
Sbjct: 459 LHAK--------NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQP--TGS 508
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ D F +SDVYS+G+VL+E+
Sbjct: 509 VLWMAPEVI-RMQDNNPFS--FQSDVYSYGIVLYEL 541
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 87.4 bits (207), Expect = 1e-16
Identities = 75/224 (33%), Positives = 115/224 (51%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G G+FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 245 LKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 302
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 303 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE- 356
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 357 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 403
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 404 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 440
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 87.4 bits (207), Expect = 1e-16
Identities = 75/224 (33%), Positives = 115/224 (51%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G G+FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 245 LKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 302
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 303 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE- 356
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 357 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 403
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 404 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 440
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 87.4 bits (207), Expect = 1e-16
Identities = 75/224 (33%), Positives = 115/224 (51%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G G+FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 232 LKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 289
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 290 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE- 343
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 344 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 390
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 391 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 427
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 87.4 bits (207), Expect = 1e-16
Identities = 75/224 (33%), Positives = 115/224 (51%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G G+FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 232 LKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 289
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 290 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE- 343
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 344 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 390
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 391 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 427
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 450 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 508
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 509 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 563
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 564 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 616
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 617 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 658
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 87.0 bits (206), Expect = 1e-16
Identities = 74/229 (32%), Positives = 118/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 556 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 614
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 615 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 669
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 670 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 722
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G R+MAPEV T TR ++DV+S+ L LWE+
Sbjct: 723 DEDNM--TKQPGNLRWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 764
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 86.2 bits (204), Expect = 2e-16
Identities = 69/216 (31%), Positives = 111/216 (51%), Gaps = 22/216 (10%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIF--SSREECSWFREA---EIYQTVMLRHE 231
++++L ++IG G FG+V+RG WRGE VAVK E+ S E+ E ML H
Sbjct: 115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHP 174
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH 291
NI+ A ++ L L+ +Y G L L + + + L+ ++ IA G+ +LH
Sbjct: 175 NIIALKAVCLEE----PNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLH 230
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGT 349
+ + P I HRDLKS NIL+ ++ S + L + ++ + + GT
Sbjct: 231 CEAL----VPVI-HRDLKSNNILLLQHIESDDMEHKTLKITDFGLAREWHKTTQMSAAGT 285
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ + + K SDV+SFG++LWE+
Sbjct: 286 YAWMAPEVIKASTFS------KGSDVWSFGVLLWEL 315
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 85.8 bits (203), Expect = 3e-16
Identities = 74/224 (33%), Positives = 114/224 (50%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G G+FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 248 LKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 305
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+ +
Sbjct: 306 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMVFIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 360 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 407 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 443
>BC062584-1|AAH62584.1| 518|Homo sapiens receptor-interacting
serine-threonine kinase 3 protein.
Length = 518
Score = 85.4 bits (202), Expect = 4e-16
Identities = 84/299 (28%), Positives = 134/299 (44%), Gaps = 41/299 (13%)
Query: 163 SGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFRE- 219
SG+ PL+ + Q +++GKG FG V+R + R G +VAVKI +S+ +
Sbjct: 9 SGAPAPLVSIEELENQ----ELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAM 64
Query: 220 AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI-K 278
A + +LR E ++ + D L+T + ENGSL L ++ L+ +
Sbjct: 65 ASLDNEFVLRLEGVIEKVNWDQDPKPA-----LVTKFMENGSLSGLLQSQCPRPWPLLCR 119
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
+ + G+ +LH P + HRDLK N+L+ L + D GL+ S
Sbjct: 120 LLKEVVLGMFYLHDQ------NPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSG 173
Query: 339 VDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
S GT Y+APE+ R+ SDVYSFG+++W A G +
Sbjct: 174 TG--SGEPGGTLGYLAPELFVNV--NRKAS--TASDVYSFGILMW--AVLAGREVE---- 221
Query: 399 PYYDCVPPDPALEDMRRVVCTEKRRPN---VPNRWHSDPVLSGISKVMKECWYQNPAAR 454
+P +P+L + VC + RP+ +P P L G+ ++M+ CW P R
Sbjct: 222 -----LPTEPSL--VYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDR 273
>AY453693-1|AAS16359.1| 518|Homo sapiens receptor interacting
protein 3 protein.
Length = 518
Score = 85.4 bits (202), Expect = 4e-16
Identities = 84/299 (28%), Positives = 134/299 (44%), Gaps = 41/299 (13%)
Query: 163 SGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFRE- 219
SG+ PL+ + Q +++GKG FG V+R + R G +VAVKI +S+ +
Sbjct: 9 SGAPAPLVSIEELENQ----ELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAM 64
Query: 220 AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI-K 278
A + +LR E ++ + D L+T + ENGSL L ++ L+ +
Sbjct: 65 ASLDNEFVLRLEGVIEKVNWDQDPKPA-----LVTKFMENGSLSGLLQSQCPRPWPLLCR 119
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
+ + G+ +LH P + HRDLK N+L+ L + D GL+ S
Sbjct: 120 LLKEVVLGMFYLHDQ------NPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSG 173
Query: 339 VDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
S GT Y+APE+ R+ SDVYSFG+++W A G +
Sbjct: 174 TG--SGEPGGTLGYLAPELFVNV--NRKAS--TASDVYSFGILMW--AVLAGREVE---- 221
Query: 399 PYYDCVPPDPALEDMRRVVCTEKRRPN---VPNRWHSDPVLSGISKVMKECWYQNPAAR 454
+P +P+L + VC + RP+ +P P L G+ ++M+ CW P R
Sbjct: 222 -----LPTEPSL--VYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDR 273
>AK075275-1|BAC11512.1| 427|Homo sapiens protein ( Homo sapiens
cDNA FLJ90794 fis, clone THYRO1001700, weakly similar to
SERINE/THREONINE PROTEIN KINASE RIP (EC 2.7.1.-). ).
Length = 427
Score = 85.4 bits (202), Expect = 4e-16
Identities = 84/299 (28%), Positives = 134/299 (44%), Gaps = 41/299 (13%)
Query: 163 SGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFRE- 219
SG+ PL+ + Q +++GKG FG V+R + R G +VAVKI +S+ +
Sbjct: 9 SGAPAPLVSIEELENQ----ELVGKGGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAM 64
Query: 220 AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI-K 278
A + +LR E ++ + D L+T + ENGSL L ++ L+ +
Sbjct: 65 ASLDNEFVLRLEGVIEKVNWDQDPKPA-----LVTKFMENGSLSGLLQSQCPRPWPLLCR 119
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
+ + G+ +LH P + HRDLK N+L+ L + D GL+ S
Sbjct: 120 LLKEVVLGMFYLHDQ------NPVLLHRDLKPSNVLLDPELHVKLADFGLSTFQGGSQSG 173
Query: 339 VDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
S GT Y+APE+ R+ SDVYSFG+++W A G +
Sbjct: 174 TG--SGEPGGTLGYLAPELFVNV--NRKAS--TASDVYSFGILMW--AVLAGREVE---- 221
Query: 399 PYYDCVPPDPALEDMRRVVCTEKRRPN---VPNRWHSDPVLSGISKVMKECWYQNPAAR 454
+P +P+L + VC + RP+ +P P L G+ ++M+ CW P R
Sbjct: 222 -----LPTEPSL--VYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDR 273
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 85.0 bits (201), Expect = 5e-16
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
+QL+ +G G+FGEVW G W G VA+K + S+ EA+I + L+H+ ++
Sbjct: 271 LQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMK--KLKHDKLVQ 328
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A +++ ++++T+Y GSL DFL +++ L+ M+ +A G+A++
Sbjct: 329 LYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE- 382
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL+S NILV + L C I D GLA + D+ T R G K
Sbjct: 383 -------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN---EYTARQGAKFP 429
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 430 IKWTAPEAALYGRFT------IKSDVWSFGILLTELVTK-GRVP 466
>Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase with
SH3 domain, leucine zipper domain and proline rich
protein.
Length = 953
Score = 85.0 bits (201), Expect = 5e-16
Identities = 68/215 (31%), Positives = 106/215 (49%), Gaps = 22/215 (10%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAE-IYQTV----MLRHEN 232
++QL +IIG G FG+V+R WRGE VAVK E AE + Q L+H N
Sbjct: 97 ELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPN 156
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ A L L+ +Y G+L L + + + L+ ++ +A G+ +LH
Sbjct: 157 IIALRGACLNP----PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHN 212
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGTK 350
D I HRDLKS NIL+ + + + D L + ++ + + GT
Sbjct: 213 D-----APVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTY 267
Query: 351 RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ ++ + K SDV+SFG++LWE+
Sbjct: 268 AWMAPEVIRLSLFS------KSSDVWSFGVLLWEL 296
>X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2
protein.
Length = 954
Score = 85.0 bits (201), Expect = 5e-16
Identities = 68/215 (31%), Positives = 106/215 (49%), Gaps = 22/215 (10%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAE-IYQTV----MLRHEN 232
++QL +IIG G FG+V+R WRGE VAVK E AE + Q L+H N
Sbjct: 97 ELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPN 156
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ A L L+ +Y G+L L + + + L+ ++ +A G+ +LH
Sbjct: 157 IIALRGACLNP----PHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHN 212
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGTK 350
D I HRDLKS NIL+ + + + D L + ++ + + GT
Sbjct: 213 D-----APVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTY 267
Query: 351 RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ ++ + K SDV+SFG++LWE+
Sbjct: 268 AWMAPEVIRLSLFS------KSSDVWSFGVLLWEL 296
>U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein
kinase protein.
Length = 847
Score = 85.0 bits (201), Expect = 5e-16
Identities = 69/216 (31%), Positives = 110/216 (50%), Gaps = 22/216 (10%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIF--SSREECSWFREA---EIYQTVMLRHE 231
++++L ++IG G FG+V+RG WRGE VAVK E+ S E+ E ML H
Sbjct: 115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHP 174
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH 291
NI+ A ++ L L+ +Y G L L + + + L+ ++ IA G+ +LH
Sbjct: 175 NIIALKAVCLEE----PNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLH 230
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGT 349
+ + P I HRDLKS NIL+ + S + L + ++ + + GT
Sbjct: 231 CEAL----VPVI-HRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGT 285
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ + + K SDV+SFG++LWE+
Sbjct: 286 YAWMAPEVIKASTFS------KGSDVWSFGVLLWEL 315
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 85.0 bits (201), Expect = 5e-16
Identities = 74/224 (33%), Positives = 114/224 (50%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
++LV+ +G +FGEVW G + G VAVK S ++ EA + + L+H+ ++
Sbjct: 245 LKLVERLGAAQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMK--QLQHQRLVR 302
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 303 LYAVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE- 356
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ NILV LSC I D GLA + D+ T R G K
Sbjct: 357 -------ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFP 403
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 404 IKWTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 440
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 85.0 bits (201), Expect = 5e-16
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
+QL+ +G G+FGEVW G W G VA+K + S+ EA+I + L+H+ ++
Sbjct: 271 LQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMK--KLKHDKLVQ 328
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A +++ ++++T+Y GSL DFL +++ L+ M+ +A G+A++
Sbjct: 329 LYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE- 382
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL+S NILV + L C I D GLA + D+ T R G K
Sbjct: 383 -------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN---EYTARQGAKFP 429
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 430 IKWTAPEAALYGRFT------IKSDVWSFGILLTELVTK-GRVP 466
>L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein.
Length = 847
Score = 85.0 bits (201), Expect = 5e-16
Identities = 69/216 (31%), Positives = 110/216 (50%), Gaps = 22/216 (10%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIF--SSREECSWFREA---EIYQTVMLRHE 231
++++L ++IG G FG+V+RG WRGE VAVK E+ S E+ E ML H
Sbjct: 115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHP 174
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH 291
NI+ A ++ L L+ +Y G L L + + + L+ ++ IA G+ +LH
Sbjct: 175 NIIALKAVCLEE----PNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLH 230
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGT 349
+ + P I HRDLKS NIL+ + S + L + ++ + + GT
Sbjct: 231 CEAL----VPVI-HRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGT 285
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ + + K SDV+SFG++LWE+
Sbjct: 286 YAWMAPEVIKASTFS------KGSDVWSFGVLLWEL 315
>BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 85.0 bits (201), Expect = 5e-16
Identities = 69/216 (31%), Positives = 110/216 (50%), Gaps = 22/216 (10%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIF--SSREECSWFREA---EIYQTVMLRHE 231
++++L ++IG G FG+V+RG WRGE VAVK E+ S E+ E ML H
Sbjct: 115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHP 174
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH 291
NI+ A ++ L L+ +Y G L L + + + L+ ++ IA G+ +LH
Sbjct: 175 NIIALKAVCLEE----PNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLH 230
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGT 349
+ + P I HRDLKS NIL+ + S + L + ++ + + GT
Sbjct: 231 CEAL----VPVI-HRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGT 285
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ + + K SDV+SFG++LWE+
Sbjct: 286 YAWMAPEVIKASTFS------KGSDVWSFGVLLWEL 315
>AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 variant protein.
Length = 847
Score = 85.0 bits (201), Expect = 5e-16
Identities = 69/216 (31%), Positives = 110/216 (50%), Gaps = 22/216 (10%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIF--SSREECSWFREA---EIYQTVMLRHE 231
++++L ++IG G FG+V+RG WRGE VAVK E+ S E+ E ML H
Sbjct: 115 QELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHP 174
Query: 232 NILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLH 291
NI+ A ++ L L+ +Y G L L + + + L+ ++ IA G+ +LH
Sbjct: 175 NIIALKAVCLEE----PNLCLVMEYAAGGPLSRALAGRRVPPHVLVNWAVQIARGMHYLH 230
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNL-SCVIGDLGLAVR-HNVSNDSVDVPSTNRVGT 349
+ + P I HRDLKS NIL+ + S + L + ++ + + GT
Sbjct: 231 CEAL----VPVI-HRDLKSNNILLLQPIESDDMEHKTLKITDFGLAREWHKTTQMSAAGT 285
Query: 350 KRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+MAPEV+ + + K SDV+SFG++LWE+
Sbjct: 286 YAWMAPEVIKASTFS------KGSDVWSFGVLLWEL 315
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 456 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 513
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 514 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 568
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 569 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 618
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 619 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 649
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 18 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 75
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 76 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 130
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 131 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 180
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 181 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 211
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 456 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 513
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 514 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 568
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 569 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 618
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 619 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 649
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 456 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 513
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 514 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 568
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 569 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 618
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 619 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 649
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 84.2 bits (199), Expect = 9e-16
Identities = 73/229 (31%), Positives = 117/229 (51%), Gaps = 28/229 (12%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECS------WFR 218
+GLP ++ +I+ +IIG G FG+V++GR R + VA+K + + CS + R
Sbjct: 551 AGLPSHFHLQLS-EIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMFCR 609
Query: 219 EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTL 276
E I L H ++ F+ A D +Q ++T Y GSLF L + +D +
Sbjct: 610 EVSI--LCQLNHPCVIQFVGACLNDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSK 664
Query: 277 IKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSN 336
+ +++ +A G+ +LH +P I HRDL S NIL+ + V+ D G + R S
Sbjct: 665 LIIAVDVAKGMEYLH-----NLTQP-IIHRDLNSHNILLYEDGHAVVADFGES-RFLQSL 717
Query: 337 DSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
D ++ T + G +MAPEV T TR ++DV+S+ L LWE+
Sbjct: 718 DEDNM--TKQPGNLLWMAPEVF--TQCTRY---TIKADVFSYALCLWEI 759
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 1182 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 1239
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 1240 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 1294
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 1295 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 1344
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 1345 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 1375
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 84.2 bits (199), Expect = 9e-16
Identities = 72/215 (33%), Positives = 111/215 (51%), Gaps = 28/215 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
QI + IG G FG V++G+W G+ VAVK+ + + ++ F+ E+ RH NI
Sbjct: 341 QITVGQRIGSGSFGTVYKGKWHGD-VAVKMLNVTAPTPQQLQAFKN-EVGVLRKTRHVNI 398
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
L F+ K QL ++T + E SL+ L + LI ++ A G+ +LH
Sbjct: 399 LLFMGYSTKP-----QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH 453
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+I HRDLKS NI + +L+ IGD GLA + + S + G+
Sbjct: 454 AK--------SIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLS--GSIL 503
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEM 385
+MAPEV+ M + +PY +SDVY+FG+VL+E+
Sbjct: 504 WMAPEVI--RMQDK--NPYSFQSDVYAFGIVLYEL 534
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 83.8 bits (198), Expect = 1e-15
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 37/224 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
+QL+ +G G+FGEVW G W G VA+K + S+ EA+I + L+H+ ++
Sbjct: 271 LQLIKRLGNGQFGEVWMGTWNGNTKVAIKTLKPGTMSPESFLEEAQIMK--KLKHDKLVQ 328
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A +++ ++++T+Y GSL DFL +++ L+ M+ +A G+A++
Sbjct: 329 LYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVDMAAQVAAGMAYIE- 382
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL+S NILV + L C I D GLA + D+ T R G K
Sbjct: 383 -------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN---EYTARQGAKFP 429
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 430 IKWTAPERALYGRFT------IKSDVWSFGILLTELVTK-GRVP 466
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 91 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 148
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 149 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 196
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 197 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 249
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 250 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 280
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 276 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 333
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 334 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 381
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 382 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 434
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 435 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 465
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 276 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 333
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 334 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 381
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 382 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 434
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 435 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 465
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 276 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 333
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 334 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 381
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 382 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 434
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 435 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 465
>AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 282 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 339
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 340 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 387
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 388 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 440
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 441 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 471
>AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 83.4 bits (197), Expect = 2e-15
Identities = 70/218 (32%), Positives = 112/218 (51%), Gaps = 37/218 (16%)
Query: 185 IGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILGFIAADN 241
+G+G FGEVW G W G VA+K + ++ +EA++ + LRHE ++ A +
Sbjct: 276 LGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKK--LRHEKLVQLYAVVS 333
Query: 242 KDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTK 298
++ ++++T+Y GSL DFL T K + L+ M+ IA+G+A++
Sbjct: 334 EE-----PIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVE------- 381
Query: 299 GKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAP 355
+ HRDL++ NILV NL C + D GLA + D+ T R G K ++ AP
Sbjct: 382 -RMNYVHRDLRAANILVGENLVCKVADFGLA---RLIEDN---EYTARQGAKFPIKWTAP 434
Query: 356 EVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
E T +SDV+SFG++L E+ + G +P
Sbjct: 435 EAALYGRFT------IKSDVWSFGILLTELTTK-GRVP 465
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 83.0 bits (196), Expect = 2e-15
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 37/227 (16%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVM-LRHENI 233
+I L+ +G G+FG V G+W+G+ +VAVK+ S E +F+EA QT+M L H +
Sbjct: 416 EITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEA---QTMMKLSHPKL 472
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTA--KSIDSNTLIKMSLSIATGLAHLH 291
+ F +K+ ++++T+Y NG L ++L + K ++ + L++M + G+A L
Sbjct: 473 VKFYGVCSKE----YPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLE 528
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK- 350
HRDL ++N LV +L + D G+ R+ + + V + VGTK
Sbjct: 529 --------SHQFIHRDLAARNCLVDRDLCVKVSDFGM-TRYVLDDQYV-----SSVGTKF 574
Query: 351 --RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395
++ APEV F +SDV++FG+++WE+ G P D
Sbjct: 575 PVKWSAPEVF------HYFKYSSKSDVWAFGILMWEVF-SLGKQPYD 614
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 83.0 bits (196), Expect = 2e-15
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 37/227 (16%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVM-LRHENI 233
+I L+ +G G+FG V G+W+G+ +VAVK+ S E +F+EA QT+M L H +
Sbjct: 416 EITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEA---QTMMKLSHPKL 472
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTA--KSIDSNTLIKMSLSIATGLAHLH 291
+ F +K+ ++++T+Y NG L ++L + K ++ + L++M + G+A L
Sbjct: 473 VKFYGVCSKE----YPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLE 528
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK- 350
HRDL ++N LV +L + D G+ R+ + + V + VGTK
Sbjct: 529 --------SHQFIHRDLAARNCLVDRDLCVKVSDFGM-TRYVLDDQYV-----SSVGTKF 574
Query: 351 --RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395
++ APEV F +SDV++FG+++WE+ G P D
Sbjct: 575 PVKWSAPEVF------HYFKYSSKSDVWAFGILMWEVF-SLGKQPYD 614
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 83.0 bits (196), Expect = 2e-15
Identities = 69/227 (30%), Positives = 118/227 (51%), Gaps = 37/227 (16%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGE-NVAVKIF--SSREECSWFREAEIYQTVM-LRHENI 233
+I L+ +G G+FG V G+W+G+ +VAVK+ S E +F+EA QT+M L H +
Sbjct: 438 EITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQEA---QTMMKLSHPKL 494
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTA--KSIDSNTLIKMSLSIATGLAHLH 291
+ F +K+ ++++T+Y NG L ++L + K ++ + L++M + G+A L
Sbjct: 495 VKFYGVCSKE----YPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCEGMAFLE 550
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK- 350
HRDL ++N LV +L + D G+ R+ + + V + VGTK
Sbjct: 551 --------SHQFIHRDLAARNCLVDRDLCVKVSDFGM-TRYVLDDQYV-----SSVGTKF 596
Query: 351 --RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDD 395
++ APEV F +SDV++FG+++WE+ G P D
Sbjct: 597 PVKWSAPEVF------HYFKYSSKSDVWAFGILMWEVF-SLGKQPYD 636
>BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein.
Length = 1104
Score = 82.2 bits (194), Expect = 4e-15
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 26/217 (11%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKI--FSSREECSWFRE---AEIYQTVMLRHEN 232
++ L +IIG G FG+V+R W G+ VAVK E+ S E E ML+H N
Sbjct: 143 ELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPN 202
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ K+ L L+ ++ G L L+ K I + L+ ++ IA G+ +LH
Sbjct: 203 IIALRGVCLKE----PNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHD 258
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAV----RHNVSNDSVDVPSTNRVG 348
+ + I HRDLKS NIL+ + GDL + ++ + + G
Sbjct: 259 EAI-----VPIIHRDLKSSNILILQKVE--NGDLSNKILKITDFGLAREWHRTTKMSAAG 311
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
T +MAPEV+ +M + K SDV+S+G++LWE+
Sbjct: 312 TYAWMAPEVIRASMFS------KGSDVWSYGVLLWEL 342
>BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein.
Length = 1103
Score = 82.2 bits (194), Expect = 4e-15
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 26/217 (11%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKI--FSSREECSWFRE---AEIYQTVMLRHEN 232
++ L +IIG G FG+V+R W G+ VAVK E+ S E E ML+H N
Sbjct: 142 ELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPN 201
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ K+ L L+ ++ G L L+ K I + L+ ++ IA G+ +LH
Sbjct: 202 IIALRGVCLKE----PNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHD 257
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAV----RHNVSNDSVDVPSTNRVG 348
+ + I HRDLKS NIL+ + GDL + ++ + + G
Sbjct: 258 EAI-----VPIIHRDLKSSNILILQKVE--NGDLSNKILKITDFGLAREWHRTTKMSAAG 310
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
T +MAPEV+ +M + K SDV+S+G++LWE+
Sbjct: 311 TYAWMAPEVIRASMFS------KGSDVWSYGVLLWEL 341
>AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein
kinase 1 protein.
Length = 1104
Score = 82.2 bits (194), Expect = 4e-15
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 26/217 (11%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKI--FSSREECSWFRE---AEIYQTVMLRHEN 232
++ L +IIG G FG+V+R W G+ VAVK E+ S E E ML+H N
Sbjct: 143 ELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPN 202
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ K+ L L+ ++ G L L+ K I + L+ ++ IA G+ +LH
Sbjct: 203 IIALRGVCLKE----PNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHD 258
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAV----RHNVSNDSVDVPSTNRVG 348
+ + I HRDLKS NIL+ + GDL + ++ + + G
Sbjct: 259 EAI-----VPIIHRDLKSSNILILQKVE--NGDLSNKILKITDFGLAREWHRTTKMSAAG 311
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
T +MAPEV+ +M + K SDV+S+G++LWE+
Sbjct: 312 TYAWMAPEVIRASMFS------KGSDVWSYGVLLWEL 342
>AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase MLK1
protein.
Length = 1066
Score = 82.2 bits (194), Expect = 4e-15
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 26/217 (11%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKI--FSSREECSWFRE---AEIYQTVMLRHEN 232
++ L +IIG G FG+V+R W G+ VAVK E+ S E E ML+H N
Sbjct: 91 ELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPN 150
Query: 233 ILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHM 292
I+ K+ L L+ ++ G L L+ K I + L+ ++ IA G+ +LH
Sbjct: 151 IIALRGVCLKE----PNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHD 206
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAV----RHNVSNDSVDVPSTNRVG 348
+ + I HRDLKS NIL+ + GDL + ++ + + G
Sbjct: 207 EAI-----VPIIHRDLKSSNILILQKVE--NGDLSNKILKITDFGLAREWHRTTKMSAAG 259
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
T +MAPEV+ +M + K SDV+S+G++LWE+
Sbjct: 260 TYAWMAPEVIRASMFS------KGSDVWSYGVLLWEL 290
>Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for
A-raf-1 oncogene. ).
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase
protein.
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein.
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog 1 protein.
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein.
Length = 609
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 312 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 369
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 370 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 424
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 425 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 474
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 475 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 511
>BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 3611
viral oncogene homolog protein.
Length = 606
Score = 81.4 bits (192), Expect = 6e-15
Identities = 75/223 (33%), Positives = 109/223 (48%), Gaps = 30/223 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 309 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 366
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 367 LLFMGFMTRPGFA-----IITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 421
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G+
Sbjct: 422 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGSVL 471
Query: 352 YMAPEVLDETMDTRQFDPYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV+ D +PY +SDVY++G+VL+E+ G++P
Sbjct: 472 WMAAEVI-RMQDP---NPYSFQSDVYAYGVVLYEL--MTGSLP 508
>AF156884-1|AAD39005.1| 518|Homo sapiens RIP-like kinase protein.
Length = 518
Score = 81.4 bits (192), Expect = 6e-15
Identities = 83/299 (27%), Positives = 132/299 (44%), Gaps = 41/299 (13%)
Query: 163 SGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWR--GENVAVKIFSSREECSWFRE- 219
SG+ PL+ + Q +++GK FG V+R + R G +VAVKI +S+ +
Sbjct: 9 SGAPAPLVSIEELENQ----ELVGKDGFGTVFRAQHRKWGYDVAVKIVNSKAISREVKAM 64
Query: 220 AEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI-K 278
A + +LR E ++ + D L+T + ENGSL L ++ L+ +
Sbjct: 65 ASLDNEFVLRLEGVIEKVNWDQDPKPA-----LVTKFMENGSLSGLLQSQCPRPWPLLCR 119
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
+ + G+ +LH P + HRDLK N+L L + D GL+ S
Sbjct: 120 LLKEVVLGMFYLHDQ------NPVLLHRDLKPSNVLPDPELHVKLADFGLSTFQGGSQSG 173
Query: 339 VDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
S GT Y+APE+ R+ SDVYSFG+++W A G +
Sbjct: 174 TG--SGEPGGTLGYLAPELFVNV--NRKAS--TASDVYSFGILMW--AVLAGREVE---- 221
Query: 399 PYYDCVPPDPALEDMRRVVCTEKRRPN---VPNRWHSDPVLSGISKVMKECWYQNPAAR 454
+P +P+L + VC + RP+ +P P L G+ ++M+ CW P R
Sbjct: 222 -----LPTEPSL--VYEAVCNRQNRPSLAELPQAGPETPGLEGLKELMQLCWSSEPKDR 273
>M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein.
Length = 298
Score = 81.0 bits (191), Expect = 8e-15
Identities = 77/225 (34%), Positives = 109/225 (48%), Gaps = 34/225 (15%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
++QL+ IG G FG V+RGRW G+ VAVK+ + E+ F+ E+ RH NI
Sbjct: 18 EVQLLKRIGTGSFGTVFRGRWHGD-VAVKVLKVSQPTAEQAQAFKN-EMQVLRKTRHVNI 75
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS--IDSNTLIKMSLSIATGLAHLH 291
L F+ + + +IT + E SL+ L D LI ++ A G+ +LH
Sbjct: 76 LPFMGFMTRPG-----VAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLH 130
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
I HRDLKS NI + L+ IGD GLA + S P G
Sbjct: 131 AK--------NIIHRDLKSNNIFLHEGLTVKIGDFGLATVK--TRWSGAQPLEQPSGPVL 180
Query: 352 YMAPEVLDETMDTRQFD--PYK-RSDVYSFGLVLWEMARRCGNMP 393
+MA EV TR D PY +SDVY++G+VL+E+ G++P
Sbjct: 181 WMAAEV------TRMQDPNPYSFQSDVYAYGVVLYEL--MTGSLP 217
>BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1
(zebrafish) protein.
Length = 1332
Score = 81.0 bits (191), Expect = 8e-15
Identities = 73/256 (28%), Positives = 120/256 (46%), Gaps = 33/256 (12%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ E+ E EI Q
Sbjct: 13 IDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED----EEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFL---TAKSIDSN 274
+ ML+ H NI + A K + G QLWL+ ++ GS+ D + ++ +
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKED 128
Query: 275 TLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNV 334
+ + I GLAHLH + HRD+K +N+L+ N + D G++ +
Sbjct: 129 CIAYICREILRGLAHLHAH--------KVIHRDIKGQNVLLTENAEVKLVDFGVSAQ--- 177
Query: 335 SNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNM 392
D +GT +MAPEV+ DE D +D RSD++S G+ EMA +
Sbjct: 178 -LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDIWSLGITAIEMAEGAPPL 233
Query: 393 PDDYQPPYYDCVPPDP 408
D + +P +P
Sbjct: 234 CDMHPMRALFLIPRNP 249
>BC001401-1|AAH01401.1| 455|Homo sapiens sterile alpha motif and
leucine zipper containing kinase AZK protein.
Length = 455
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related
kinase isoform beta protein.
Length = 1312
Score = 81.0 bits (191), Expect = 8e-15
Identities = 73/256 (28%), Positives = 120/256 (46%), Gaps = 33/256 (12%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ E+ E EI Q
Sbjct: 13 IDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED----EEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFL---TAKSIDSN 274
+ ML+ H NI + A K + G QLWL+ ++ GS+ D + ++ +
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKED 128
Query: 275 TLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNV 334
+ + I GLAHLH + HRD+K +N+L+ N + D G++ +
Sbjct: 129 CIAYICREILRGLAHLHAH--------KVIHRDIKGQNVLLTENAEVKLVDFGVSAQ--- 177
Query: 335 SNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNM 392
D +GT +MAPEV+ DE D +D RSD++S G+ EMA +
Sbjct: 178 -LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDIWSLGITAIEMAEGAPPL 233
Query: 393 PDDYQPPYYDCVPPDP 408
D + +P +P
Sbjct: 234 CDMHPMRALFLIPRNP 249
>AF480462-1|AAL85892.1| 455|Homo sapiens mixed lineage
kinase-related kinase MRK-beta protein.
Length = 455
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AF480461-1|AAL85891.1| 800|Homo sapiens mixed lineage
kinase-related kinase MRK-alpha protein.
Length = 800
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AF465843-1|AAO33376.1| 312|Homo sapiens cervical cancer suppressor
gene-4 protein protein.
Length = 312
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AF325454-1|AAK11615.1| 455|Homo sapiens mixed lineage kinase
protein.
Length = 455
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AF251441-1|AAF65822.1| 800|Homo sapiens sterile-alpha motif and
leucine zipper containing kinase AZK protein.
Length = 800
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AF238255-1|AAF63490.1| 800|Homo sapiens mixed lineage kinase ZAK
protein.
Length = 800
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AB208974-1|BAD92211.1| 845|Homo sapiens Plaucible mixed-lineage
kinase protein variant protein.
Length = 845
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 61 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 113
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 114 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 169
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 170 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 218
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 219 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 247
>AB049734-1|BAB16445.1| 455|Homo sapiens MLTK-beta protein.
Length = 455
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AB049733-1|BAB16444.1| 800|Homo sapiens MLTK-alpha protein.
Length = 800
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-2
protein.
Length = 1303
Score = 81.0 bits (191), Expect = 8e-15
Identities = 73/256 (28%), Positives = 120/256 (46%), Gaps = 33/256 (12%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ E+ E EI Q
Sbjct: 13 IDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED----EEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFL---TAKSIDSN 274
+ ML+ H NI + A K + G QLWL+ ++ GS+ D + ++ +
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKED 128
Query: 275 TLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNV 334
+ + I GLAHLH + HRD+K +N+L+ N + D G++ +
Sbjct: 129 CIAYICREILRGLAHLHAH--------KVIHRDIKGQNVLLTENAEVKLVDFGVSAQ--- 177
Query: 335 SNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNM 392
D +GT +MAPEV+ DE D +D RSD++S G+ EMA +
Sbjct: 178 -LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDIWSLGITAIEMAEGAPPL 233
Query: 393 PDDYQPPYYDCVPPDP 408
D + +P +P
Sbjct: 234 CDMHPMRALFLIPRNP 249
>AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related
kinase MINK-1 protein.
Length = 1295
Score = 81.0 bits (191), Expect = 8e-15
Identities = 73/256 (28%), Positives = 120/256 (46%), Gaps = 33/256 (12%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ E+ E EI Q
Sbjct: 13 IDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTED----EEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFL---TAKSIDSN 274
+ ML+ H NI + A K + G QLWL+ ++ GS+ D + ++ +
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLWLVMEFCGAGSVTDLVKNTKGNALKED 128
Query: 275 TLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNV 334
+ + I GLAHLH + HRD+K +N+L+ N + D G++ +
Sbjct: 129 CIAYICREILRGLAHLHAH--------KVIHRDIKGQNVLLTENAEVKLVDFGVSAQ--- 177
Query: 335 SNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNM 392
D +GT +MAPEV+ DE D +D RSD++S G+ EMA +
Sbjct: 178 -LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDIWSLGITAIEMAEGAPPL 233
Query: 393 PDDYQPPYYDCVPPDP 408
D + +P +P
Sbjct: 234 CDMHPMRALFLIPRNP 249
>AB030034-1|BAB12040.1| 800|Homo sapiens plaucible mixed-lineage
kinase protein protein.
Length = 800
Score = 81.0 bits (191), Expect = 8e-15
Identities = 64/215 (29%), Positives = 106/215 (49%), Gaps = 33/215 (15%)
Query: 179 IQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
+Q + G G FG V+R +W + + VAVK E +EAEI +L H NI+ F
Sbjct: 16 LQFFENCGGGSFGSVYRAKWISQDKEVAVKKLLKIE-----KEAEILS--VLSHRNIIQF 68
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFLTA---KSIDSNTLIKMSLSIATGLAHLHMD 293
+ ++T+Y GSL+D++ + + +D + ++ + +A G+ +LHM+
Sbjct: 69 YGVILEP----PNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHME 124
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
+ HRDLKS+N+++ ++ I D G + HN + VGT +M
Sbjct: 125 -----APVKVIHRDLKSRNVVIAADGVLKICDFGASRFHN------HTTHMSLVGTFPWM 173
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
APEV+ + + D YS+G+VLWEM R
Sbjct: 174 APEVI------QSLPVSETCDTYSYGVVLWEMLTR 202
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 79.4 bits (187), Expect = 3e-14
Identities = 69/221 (31%), Positives = 110/221 (49%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV++GR + G+ VA+K +S ++ + EA I
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG--QFD 676
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ K + +IT++ ENG+L FL L+ M IA G+
Sbjct: 677 HPNIIRLEGVVTKSR----PVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + HRDL ++NILV SNL C + D GL+ + +D+ D T+ +
Sbjct: 733 KYL--------AEMNYVHRDLAARNILVNSNLVCKVSDFGLS--RYLQDDTSDPTYTSSL 782
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 783 GGKIPVRWTAPEAI----AYRKFT--SASDVWSYGIVMWEV 817
>BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein.
Length = 542
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AL451136-3|CAI13092.1| 542|Homo sapiens testis-specific kinase 2
protein.
Length = 542
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AL451136-2|CAI13093.1| 571|Homo sapiens testis-specific kinase 2
protein.
Length = 571
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AL359540-13|CAI21723.1| 542|Homo sapiens testis-specific kinase 2
protein.
Length = 542
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AL359540-12|CAI21724.1| 571|Homo sapiens testis-specific kinase 2
protein.
Length = 571
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AB057597-1|BAB62909.1| 571|Homo sapiens testicular protein kinase
2 protein.
Length = 571
Score = 79.4 bits (187), Expect = 3e-14
Identities = 73/222 (32%), Positives = 115/222 (51%), Gaps = 32/222 (14%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ +A+K+ + S + +E ++ L H NIL F+
Sbjct: 64 IGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANMLKEVQLMNR--LSHPNILRFMGVCV 121
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTAK-SIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y +G+L L + + +K++ IA GL++LH KG
Sbjct: 122 HQG----QLHALTEYINSGNLEQLLDSNLHLPWTVRVKLAYDIAVGLSYLHF-----KG- 171
Query: 301 PAIAHRDLKSKNILVK---SNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
I HRDL SKN L+K + S V+ D GLA + + + S+ VG+ +MAPEV
Sbjct: 172 --IFHRDLTSKNCLIKRDENGYSAVVADFGLAEK--IPDVSMGSEKLAVVGSPFWMAPEV 227
Query: 358 LDETMDTRQFDPY-KRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +PY +++DV+S+G++L E+ R P DY P
Sbjct: 228 LRD-------EPYNEKADVFSYGIILCEIIARIQADP-DYLP 261
>AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein.
Length = 1385
Score = 79.4 bits (187), Expect = 3e-14
Identities = 79/272 (29%), Positives = 129/272 (47%), Gaps = 37/272 (13%)
Query: 154 DMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSR 211
DM + + S + L R A +LV+++G G +G+V++GR G+ A+K+
Sbjct: 25 DMASDSPARSLDEIDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM--- 81
Query: 212 EECSWFREAEIYQTV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFD 264
+ + E EI Q + ML+ H NI + A K N G QLWL+ ++ GS+ D
Sbjct: 82 -DVTGDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTD 140
Query: 265 FLTAKSIDSNTLIK-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNL 319
+ K+ NTL + + I GL+HLH + + HRD+K +N+L+ N
Sbjct: 141 LI--KNTKGNTLKEEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENA 190
Query: 320 SCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYS 377
+ D G++ + D +GT +MAPEV+ DE D +D +SD++S
Sbjct: 191 EVKLVDFGVSAQ----LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWS 243
Query: 378 FGLVLWEMARRCGNMPDDYQPPYYDCVPPDPA 409
G+ EMA + D + +P +PA
Sbjct: 244 LGITAIEMAEGAPPLCDMHPMRALFLIPRNPA 275
>U43586-1|AAC50354.1| 635|Homo sapiens KSR1 protein.
Length = 635
Score = 79.0 bits (186), Expect = 3e-14
Identities = 70/224 (31%), Positives = 113/224 (50%), Gaps = 31/224 (13%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFS----SREECSWFREAEIYQTVMLRHENI 233
Q++L + IG+GR+G V RGRW GE VA+++ +++ F++ E+ RHEN+
Sbjct: 348 QVELGEPIGQGRWGRVHRGRWHGE-VAIRLLEMDGHNQDHLKLFKK-EVMNYRQTRHENV 405
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFL--TAKSIDSNTLIKMSLSIATGLAHLH 291
+ F+ A L +IT + + +L F+ S+D N +++ I G+ +LH
Sbjct: 406 VLFMGACMNP----PHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLH 461
Query: 292 MDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
KG I H+DLKSKN+ N VI D GL +S + N++
Sbjct: 462 -----AKG---IVHKDLKSKNVFY-DNGKVVITDFGL---FGISGVVREGRRENQLKLSH 509
Query: 352 ----YMAPEVLDETMDTRQFD--PY-KRSDVYSFGLVLWEMARR 388
Y+APE++ E + D P+ K +DVY+FG V +E+ R
Sbjct: 510 DWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQAR 553
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 79.0 bits (186), Expect = 3e-14
Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 27/221 (12%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
IQL+ +G G+FGEVW G W VAVK S + + REA+I + LRH ++
Sbjct: 234 IQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKN--LRHPKLIQ 291
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+ +GSL ++L T I + M+ +A+G+A+L
Sbjct: 292 LYAVCTLED----PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE- 346
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352
HRDL ++N+LV + + D GLA V N+ + ++
Sbjct: 347 -------SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
APE + + +F +SDV+SFG++L+E+ G MP
Sbjct: 400 TAPEAI----RSNKFS--IKSDVWSFGILLYEII-TYGKMP 433
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 79.0 bits (186), Expect = 3e-14
Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 27/221 (12%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
IQL+ +G G+FGEVW G W VAVK S + + REA+I + LRH ++
Sbjct: 234 IQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKN--LRHPKLIQ 291
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+ +GSL ++L T I + M+ +A+G+A+L
Sbjct: 292 LYAVCTLED----PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE- 346
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352
HRDL ++N+LV + + D GLA V N+ + ++
Sbjct: 347 -------SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
APE + + +F +SDV+SFG++L+E+ G MP
Sbjct: 400 TAPEAI----RSNKFS--IKSDVWSFGILLYEII-TYGKMP 433
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 226 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 283
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 284 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 338
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 339 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 385
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 386 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 415
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 304
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 305 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 360 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 407 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 436
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 304
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 305 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 360 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 407 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 436
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 304
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 305 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 360 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 407 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 436
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 304
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 305 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 360 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 407 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 436
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 247 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 304
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 305 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 359
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 360 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 406
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 407 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 436
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 374
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 375 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 429
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 430 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 476
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 477 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 506
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 79.0 bits (186), Expect = 3e-14
Identities = 69/216 (31%), Positives = 109/216 (50%), Gaps = 35/216 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAEIYQTVMLRHENILG 235
I+LV +G G+FGEVW G + VAVK + ++ EA + +T L+H+ ++
Sbjct: 317 IKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKT--LQHDKLVR 374
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+Y GSL DFL + + LI S IA G+A++
Sbjct: 375 LYAVVTREE----PIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIE- 429
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK-- 350
+ HRDL++ N+LV +L C I D GLA V D+ T R G K
Sbjct: 430 -------RKNYIHRDLRAANVLVSESLMCKIADFGLA---RVIEDN---EYTAREGAKFP 476
Query: 351 -RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
++ APE ++ T +SDV+SFG++L+E+
Sbjct: 477 IKWTAPEAINFGCFT------IKSDVWSFGILLYEI 506
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 79.0 bits (186), Expect = 3e-14
Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 27/221 (12%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
IQL+ +G G+FGEVW G W VAVK S + + REA+I + LRH ++
Sbjct: 234 IQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKN--LRHPKLIQ 291
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+ +GSL ++L T I + M+ +A+G+A+L
Sbjct: 292 LYAVCTLED----PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE- 346
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352
HRDL ++N+LV + + D GLA V N+ + ++
Sbjct: 347 -------SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
APE + + +F +SDV+SFG++L+E+ G MP
Sbjct: 400 TAPEAI----RSNKFS--IKSDVWSFGILLYEII-TYGKMP 433
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 79.0 bits (186), Expect = 3e-14
Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 27/221 (12%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
IQL+ +G G+FGEVW G W VAVK S + + REA+I + LRH ++
Sbjct: 234 IQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKN--LRHPKLIQ 291
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+ +GSL ++L T I + M+ +A+G+A+L
Sbjct: 292 LYAVCTLED----PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE- 346
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352
HRDL ++N+LV + + D GLA V N+ + ++
Sbjct: 347 -------SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
APE + + +F +SDV+SFG++L+E+ G MP
Sbjct: 400 TAPEAI----RSNKFS--IKSDVWSFGILLYEII-TYGKMP 433
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 79.0 bits (186), Expect = 3e-14
Identities = 66/221 (29%), Positives = 108/221 (48%), Gaps = 27/221 (12%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF--SSREECSWFREAEIYQTVMLRHENILG 235
IQL+ +G G+FGEVW G W VAVK S + + REA+I + LRH ++
Sbjct: 234 IQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKN--LRHPKLIQ 291
Query: 236 FIAADNKDNGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHM 292
A ++ +++IT+ +GSL ++L T I + M+ +A+G+A+L
Sbjct: 292 LYAVCTLED----PIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVASGMAYLE- 346
Query: 293 DIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRY 352
HRDL ++N+LV + + D GLA V N+ + ++
Sbjct: 347 -------SRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 353 MAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
APE + + +F +SDV+SFG++L+E+ G MP
Sbjct: 400 TAPEAI----RSNKFS--IKSDVWSFGILLYEII-TYGKMP 433
>DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYNEKCDVFSWGIILWEVITR 225
>BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kinase
HGK protein.
Length = 1239
Score = 78.6 bits (185), Expect = 4e-14
Identities = 73/248 (29%), Positives = 117/248 (47%), Gaps = 29/248 (11%)
Query: 173 RSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVML-R 229
R A +LV+++G G +G+V++GR G+ A+K+ E+ + EI
Sbjct: 19 RDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSH 78
Query: 230 HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIK-----MSLS 282
H NI + A K + G QLWL+ ++ GS+ D + K+ NTL + +S
Sbjct: 79 HRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLV--KNTKGNTLKEDWIAYISRE 136
Query: 283 IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVP 342
I GLAHLH+ + HRD+K +N+L+ N + D G++ + D
Sbjct: 137 ILRGLAHLHIH--------HVIHRDIKGQNVLLTENAEVKLVDFGVSAQ----LDRTVGR 184
Query: 343 STNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPY 400
+GT +MAPEV+ DE D +D RSD++S G+ EMA + D +
Sbjct: 185 RNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDLWSCGITAIEMAEGAPPLCDMHPMRA 241
Query: 401 YDCVPPDP 408
+P +P
Sbjct: 242 LFLIPRNP 249
>AL121964-4|CAI19612.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121964-3|CAI19611.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 579
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 606
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 491
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated protein
kinase kinase kinase 7 protein.
Length = 518
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kinase
splice variant d protein.
Length = 491
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK
protein.
Length = 1165
Score = 78.6 bits (185), Expect = 4e-14
Identities = 73/248 (29%), Positives = 117/248 (47%), Gaps = 29/248 (11%)
Query: 173 RSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQTVML-R 229
R A +LV+++G G +G+V++GR G+ A+K+ E+ + EI
Sbjct: 19 RDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSH 78
Query: 230 HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLIK-----MSLS 282
H NI + A K + G QLWL+ ++ GS+ D + K+ NTL + +S
Sbjct: 79 HRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLV--KNTKGNTLKEDWIAYISRE 136
Query: 283 IATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVP 342
I GLAHLH+ + HRD+K +N+L+ N + D G++ + D
Sbjct: 137 ILRGLAHLHIH--------HVIHRDIKGQNVLLTENAEVKLVDFGVSAQ----LDRTVGR 184
Query: 343 STNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQPPY 400
+GT +MAPEV+ DE D +D RSD++S G+ EMA + D +
Sbjct: 185 RNTFIGTPYWMAPEVIACDENPDA-TYD--YRSDLWSCGITAIEMAEGAPPLCDMHPMRA 241
Query: 401 YDCVPPDP 408
+P +P
Sbjct: 242 LFLIPRNP 249
>AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kinase
1c protein.
Length = 518
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kinase
1b protein.
Length = 606
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kinase
1a protein.
Length = 579
Score = 78.6 bits (185), Expect = 4e-14
Identities = 63/217 (29%), Positives = 106/217 (48%), Gaps = 30/217 (13%)
Query: 177 RQIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGF 236
++I++ +++G+G FG V + +WR ++VA+K S E F E+ Q + H NI+
Sbjct: 34 KEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAF-IVELRQLSRVNHPNIVKL 92
Query: 237 IAADNKDNGTWTQLWLITDYHENGSLFDFL-TAKSIDSNT---LIKMSLSIATGLAHLHM 292
A + L+ +Y E GSL++ L A+ + T + L + G+A+LH
Sbjct: 93 YGA------CLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLH- 145
Query: 293 DIVGTKGKPAIAHRDLKSKN-ILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKR 351
+ A+ HRDLK N +LV I D G A + TN G+
Sbjct: 146 ----SMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTAC-------DIQTHMTNNKGSAA 194
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARR 388
+MAPEV + + + ++ DV+S+G++LWE+ R
Sbjct: 195 WMAPEVFEGS------NYSEKCDVFSWGIILWEVITR 225
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 78.2 bits (184), Expect = 6e-14
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 37/238 (15%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAE 221
SGL R + L +G+G F EVW G W G VA+K + S+ EA+
Sbjct: 205 SGLAKDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQ 264
Query: 222 IYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLT---AKSIDSNTLIK 278
I + L+H+ ++ A +++ ++++T+Y GSL DFL +++ L+
Sbjct: 265 IMKK--LKHDKLVQLYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 317
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
M+ +A G+A++ + HRDL+S NILV + L C I D GLA + D+
Sbjct: 318 MAAQVAAGMAYIE--------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN 366
Query: 339 VDVPSTNRVGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
T R G K ++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 367 ---EYTARQGAKFPIKWTAPEAALYGRFT------IKSDVWSFGILLTELVTK-GRVP 414
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 78.2 bits (184), Expect = 6e-14
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 37/238 (15%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAE 221
SGL R + L +G+G F EVW G W G VA+K + S+ EA+
Sbjct: 254 SGLAKDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQ 313
Query: 222 IYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLT---AKSIDSNTLIK 278
I + L+H+ ++ A +++ ++++T+Y GSL DFL +++ L+
Sbjct: 314 IMKK--LKHDKLVQLYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 366
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
M+ +A G+A++ + HRDL+S NILV + L C I D GLA + D+
Sbjct: 367 MAAQVAAGMAYIE--------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN 415
Query: 339 VDVPSTNRVGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
T R G K ++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 416 ---EYTARQGAKFPIKWTAPEAALYGRFT------IKSDVWSFGILLTELVTK-GRVP 463
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 78.2 bits (184), Expect = 6e-14
Identities = 68/221 (30%), Positives = 110/221 (49%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV++GR + G+ VA+K +S ++ + EA I
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG--QFD 676
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ K + +IT++ ENG+L FL L+ M IA G+
Sbjct: 677 HPNIIRLEGVVTKSR----PVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + HRDL ++NIL+ SNL C + D GL+ + +D+ D T+ +
Sbjct: 733 KYL--------AEMNYVHRDLAARNILLNSNLVCKVSDFGLS--RYLQDDTSDPTYTSSL 782
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 783 GGKIPVRWTAPEAI----AYRKFT--SASDVWSYGIVMWEV 817
>AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 8 protein.
Length = 1268
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 7 protein.
Length = 1297
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 6 protein.
Length = 1323
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 5 protein.
Length = 1276
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 4 protein.
Length = 1352
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 3 protein.
Length = 1305
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 2 protein.
Length = 1331
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 1 protein.
Length = 1360
Score = 78.2 bits (184), Expect = 6e-14
Identities = 76/259 (29%), Positives = 124/259 (47%), Gaps = 37/259 (14%)
Query: 167 LPLLVQRSIARQIQLVDIIGKGRFGEVWRGRW--RGENVAVKIFSSREECSWFREAEIYQ 224
+ L R A +LV+++G G +G+V++GR G+ A+K+ + + E EI Q
Sbjct: 13 IDLSALRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKVM----DVTGDEEEEIKQ 68
Query: 225 TV-MLR----HENILGFIAADNKDN--GTWTQLWLITDYHENGSLFDFLTAKSIDSNTLI 277
+ ML+ H NI + A K N G QLWL+ ++ GS+ D + K+ NTL
Sbjct: 69 EINMLKKYSHHRNIATYYGAFIKKNPPGMDDQLWLVMEFCGAGSVTDLI--KNTKGNTLK 126
Query: 278 K-----MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRH 332
+ + I GL+HLH + + HRD+K +N+L+ N + D G++ +
Sbjct: 127 EEWIAYICREILRGLSHLH--------QHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQ- 177
Query: 333 NVSNDSVDVPSTNRVGTKRYMAPEVL--DETMDTRQFDPYKRSDVYSFGLVLWEMARRCG 390
D +GT +MAPEV+ DE D +D +SD++S G+ EMA
Sbjct: 178 ---LDRTVGRRNTFIGTPYWMAPEVIACDENPDA-TYD--FKSDLWSLGITAIEMAEGAP 231
Query: 391 NMPDDYQPPYYDCVPPDPA 409
+ D + +P +PA
Sbjct: 232 PLCDMHPMRALFLIPRNPA 250
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 77.8 bits (183), Expect = 8e-14
Identities = 82/255 (32%), Positives = 122/255 (47%), Gaps = 36/255 (14%)
Query: 159 TTSGSGSGLP--LLVQRSIARQIQLVDI------IGKGRFGEVWRGRWR--GENVAVKIF 208
T G G G P V RS + VD IG G F EV++ R R G+ + +K+
Sbjct: 29 TGGGPGRGRPSSYRVLRSAVSSLARVDDFHCAEKIGAGFFSEVYKVRHRQSGQVMVLKMN 88
Query: 209 S-SREECSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLT 267
+ RE ++ LRH NIL F+ QL +T+Y G+L L+
Sbjct: 89 KLPSNRGNTLREVQLMNR--LRHPNILRFMGVCVHQG----QLHALTEYMNGGTLEQLLS 142
Query: 268 A-KSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSN---LSCVI 323
+ + + + ++L IA GL +LH +KG + HRDL SKN LV+ + V+
Sbjct: 143 SPEPLSWPVRLHLALDIARGLRYLH-----SKG---VFHRDLTSKNCLVRREDRGFTAVV 194
Query: 324 GDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLW 383
GD GLA + V + VG+ +MAPEVL + +D +++DV++FG+VL
Sbjct: 195 GDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGEL----YD--EKADVFAFGIVLC 248
Query: 384 EMARRCGNMPDDYQP 398
E+ R P DY P
Sbjct: 249 ELIARVPADP-DYLP 262
>AC073410-1|AAX88941.1| 296|Homo sapiens unknown protein.
Length = 296
Score = 77.8 bits (183), Expect = 8e-14
Identities = 37/117 (31%), Positives = 69/117 (58%), Gaps = 1/117 (0%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIA 238
++L+++IG+GR+G V++G VAVK+FS ++ E IY+ ++ H+NI FI
Sbjct: 177 LKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVPLMEHDNIARFIV 236
Query: 239 ADNKDNGTW-TQLWLITDYHENGSLFDFLTAKSIDSNTLIKMSLSIATGLAHLHMDI 294
D + + L+ +Y+ NGSL +L+ + D + +++ S+ GLA+LH ++
Sbjct: 237 GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVSSCRLAHSVTRGLAYLHTEL 293
>AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing
kinase protein.
Length = 966
Score = 77.8 bits (183), Expect = 8e-14
Identities = 68/212 (32%), Positives = 105/212 (49%), Gaps = 36/212 (16%)
Query: 178 QIQLVDIIGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFI 237
+I + +G G G V+ G++R E VA+K RE+ E +I L+H NI+ F
Sbjct: 167 EISELQWLGSGAQGAVFLGKFRAEEVAIK--KVREQ----NETDIKHLRKLKHPNIIAF- 219
Query: 238 AADNKDNGTWTQL---WLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMD 293
G TQ +I +Y +G L++ L A + I L+ S IA+G+ +LH+
Sbjct: 220 ------KGVCTQAPCYCIIMEYCAHGQLYEVLRAGRKITPRLLVDWSTGIASGMNYLHLH 273
Query: 294 IVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYM 353
I HRDLKS N+LV + I D G + +S+ S + + GT +M
Sbjct: 274 --------KIIHRDLKSPNVLVTHTDAVKISDFGTS--KELSDKSTKM---SFAGTVAWM 320
Query: 354 APEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
APEV+ R ++ D++SFG+VLWE+
Sbjct: 321 APEVI------RNEPVSEKVDIWSFGVVLWEL 346
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 77.0 bits (181), Expect = 1e-13
Identities = 71/222 (31%), Positives = 107/222 (48%), Gaps = 33/222 (14%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFSSREECSWFREAEIYQTVMLRHENILGFI 237
++LV+ +G G+FG G G VAVK + AE L+H+ ++
Sbjct: 246 LKLVERLGAGQFGRCGWGTTTGTTKVAVKSLKQGSMSAGRLPAEANLMKQLQHQRLVRLY 305
Query: 238 AADNKDNGTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDI 294
A ++ +++IT+Y ENGSL DFL S + N L+ M+ IA G+A +
Sbjct: 306 AVVTQE-----PIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIE--- 357
Query: 295 VGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTK---R 351
+ HRDL++ NILV LSC I D GLA + D+ T R G K +
Sbjct: 358 -----ERNYIHRDLRAANILVSDTLSCKIADFGLA---RLIEDN---EYTAREGAKFPIK 406
Query: 352 YMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
+ APE ++ T +SDV+SFG++L E+ G +P
Sbjct: 407 WTAPEAINYGTFT------IKSDVWSFGILLTEIVTH-GRIP 441
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/238 (30%), Positives = 115/238 (48%), Gaps = 37/238 (15%)
Query: 165 SGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGEN-VAVKIFS--SREECSWFREAE 221
SGL R + L +G+G F EVW G W G VA+K + S+ EA+
Sbjct: 254 SGLAKDAWEVARRSLCLEKKLGQGCFAEVWLGTWNGNTKVAIKTLKPGTMSPESFLEEAQ 313
Query: 222 IYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLT---AKSIDSNTLIK 278
I + L+H+ ++ A +++ ++++T+Y GSL DFL +++ L+
Sbjct: 314 IMKK--LKHDKLVQLYAVVSEE-----PIYIVTEYMNKGSLLDFLKDGEGRALKLPNLVD 366
Query: 279 MSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDS 338
M+ +A G+A++ + HRDL+S NILV + L C I D GLA + D+
Sbjct: 367 MAAQVAAGMAYIE--------RMNYIHRDLRSANILVGNGLICKIADFGLA---RLIEDN 415
Query: 339 VDVPSTNRVGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMP 393
T R G K ++ APE T +SDV+SFG++L E+ + G +P
Sbjct: 416 ---EYTARQGAKFPIKWTAPERALYGRFT------IKSDVWSFGILLTELVTK-GRVP 463
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/221 (32%), Positives = 111/221 (50%), Gaps = 28/221 (12%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ + +K+ + RE ++ LRH NIL F+
Sbjct: 63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNR--LRHPNILRFMGVCV 120
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y G+L L++ + + + ++L IA GL +LH +KG
Sbjct: 121 HQG----QLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLH-----SKG- 170
Query: 301 PAIAHRDLKSKNILVKSN---LSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
+ HRDL SKN LV+ + V+GD GLA + V + VG+ +MAPEV
Sbjct: 171 --VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEV 228
Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +D +++DV++FG+VL E+ R P DY P
Sbjct: 229 LRGEL----YD--EKADVFAFGIVLCELIARVPADP-DYLP 262
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/221 (32%), Positives = 111/221 (50%), Gaps = 28/221 (12%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ + +K+ + RE ++ LRH NIL F+
Sbjct: 63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNR--LRHPNILRFMGVCV 120
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y G+L L++ + + + ++L IA GL +LH +KG
Sbjct: 121 HQG----QLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLH-----SKG- 170
Query: 301 PAIAHRDLKSKNILVKSN---LSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
+ HRDL SKN LV+ + V+GD GLA + V + VG+ +MAPEV
Sbjct: 171 --VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEV 228
Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +D +++DV++FG+VL E+ R P DY P
Sbjct: 229 LRGEL----YD--EKADVFAFGIVLCELIARVPADP-DYLP 262
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 77.0 bits (181), Expect = 1e-13
Identities = 72/221 (32%), Positives = 111/221 (50%), Gaps = 28/221 (12%)
Query: 185 IGKGRFGEVWRGRWR--GENVAVKIFS-SREECSWFREAEIYQTVMLRHENILGFIAADN 241
IG G F EV++ R R G+ + +K+ + RE ++ LRH NIL F+
Sbjct: 63 IGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRGNTLREVQLMNR--LRHPNILRFMGVCV 120
Query: 242 KDNGTWTQLWLITDYHENGSLFDFLTA-KSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
QL +T+Y G+L L++ + + + ++L IA GL +LH +KG
Sbjct: 121 HQG----QLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIARGLRYLH-----SKG- 170
Query: 301 PAIAHRDLKSKNILVKSN---LSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEV 357
+ HRDL SKN LV+ + V+GD GLA + V + VG+ +MAPEV
Sbjct: 171 --VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEV 228
Query: 358 LDETMDTRQFDPYKRSDVYSFGLVLWEMARRCGNMPDDYQP 398
L + +D +++DV++FG+VL E+ R P DY P
Sbjct: 229 LRGEL----YD--EKADVFAFGIVLCELIARVPADP-DYLP 262
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 76.6 bits (180), Expect = 2e-13
Identities = 74/253 (29%), Positives = 122/253 (48%), Gaps = 41/253 (16%)
Query: 150 TTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF 208
TT+ ++ T G + + S+ +++L G+G FGEVW G W G VA+K
Sbjct: 252 TTVCPTVKPQTQGLAKDAWEIPRESLRLEVKL----GQGCFGEVWMGTWNGTTKVAIKTL 307
Query: 209 SSREEC--SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL 266
++ +EA+I + LRH+ ++ A +++ ++++T++ GSL DFL
Sbjct: 308 KPGTMMPEAFLQEAQIMKK--LRHDKLVPLYAVVSEE-----PIYIVTEFMSKGSLLDFL 360
Query: 267 T---AKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVI 323
K + L+ M+ IA G+A++ + HRDL++ NILV NL C I
Sbjct: 361 KEGDGKYLKLPQLVDMAAQIADGMAYIE--------RMNYIHRDLRAANILVGENLVCKI 412
Query: 324 GDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGL 380
D GLA + D+ T R G K ++ APE T +SDV+SFG+
Sbjct: 413 ADFGLA---RLIEDN---EYTARQGAKFPIKWTAPEAALYGRFT------IKSDVWSFGI 460
Query: 381 VLWEMARRCGNMP 393
+ E+ + G +P
Sbjct: 461 LQTELVTK-GRVP 472
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 76.6 bits (180), Expect = 2e-13
Identities = 74/253 (29%), Positives = 122/253 (48%), Gaps = 41/253 (16%)
Query: 150 TTIRDMIELTTSGSGSGLPLLVQRSIARQIQLVDIIGKGRFGEVWRGRWRGEN-VAVKIF 208
TT+ ++ T G + + S+ +++L G+G FGEVW G W G VA+K
Sbjct: 252 TTVCPTVKPQTQGLAKDAWEIPRESLRLEVKL----GQGCFGEVWMGTWNGTTKVAIKTL 307
Query: 209 SSREEC--SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFL 266
++ +EA+I + LRH+ ++ A +++ ++++T++ GSL DFL
Sbjct: 308 KPGTMMPEAFLQEAQIMKK--LRHDKLVPLYAVVSEE-----PIYIVTEFMSKGSLLDFL 360
Query: 267 T---AKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVI 323
K + L+ M+ IA G+A++ + HRDL++ NILV NL C I
Sbjct: 361 KEGDGKYLKLPQLVDMAAQIADGMAYIE--------RMNYIHRDLRAANILVGENLVCKI 412
Query: 324 GDLGLAVRHNVSNDSVDVPSTNRVGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGL 380
D GLA + D+ T R G K ++ APE T +SDV+SFG+
Sbjct: 413 ADFGLA---RLIEDN---EYTARQGAKFPIKWTAPEAALYGRFT------IKSDVWSFGI 460
Query: 381 VLWEMARRCGNMP 393
+ E+ + G +P
Sbjct: 461 LQTELVTK-GRVP 472
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 76.6 bits (180), Expect = 2e-13
Identities = 59/205 (28%), Positives = 101/205 (49%), Gaps = 25/205 (12%)
Query: 185 IGKGRFGEVWRGRWRGE-NVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKD 243
+G+G FGEVW G W G VA+K+ S EI LRHE ++ A +
Sbjct: 236 LGEGYFGEVWEGLWLGSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHERLIRLHAVCSGG 295
Query: 244 NGTWTQLWLITDYHENGSLFDFL---TAKSIDSNTLIKMSLSIATGLAHLHMDIVGTKGK 300
++++T+ G+L FL +++ L+ + +A G+++L +
Sbjct: 296 E----PVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMSYLE--------E 343
Query: 301 PAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDE 360
+ HRDL ++N+LV L+C + D GLA + D + PS++ ++ AP E
Sbjct: 344 QRVVHRDLAARNVLVDDGLACKVADFGLA---RLLKDDIYSPSSSSKIPVKWTAP----E 396
Query: 361 TMDTRQFDPYKRSDVYSFGLVLWEM 385
+ R F ++SDV+SFG++L E+
Sbjct: 397 AANYRVFS--QKSDVWSFGVLLHEV 419
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 76.6 bits (180), Expect = 2e-13
Identities = 68/221 (30%), Positives = 109/221 (49%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV++GR + G+ VA+K +S ++ + EA I
Sbjct: 608 VKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG--QFD 665
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ K + +IT++ ENG+L FL L+ M IA G+
Sbjct: 666 HPNIIRLEGVVTKSR----PVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 721
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + HRDL ++NILV SNL C + D GL+ + +D+ D T+ +
Sbjct: 722 KYL--------AEMNYVHRDLAARNILVNSNLVCKVSDFGLS--RYLQDDTSDPTYTSSL 771
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SDV+S+G+ +WE+
Sbjct: 772 GGKIPVRWTAPEAI----AYRKFT--SASDVWSYGIRMWEV 806
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 76.6 bits (180), Expect = 2e-13
Identities = 68/221 (30%), Positives = 109/221 (49%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV++GR + G+ VA+K +S ++ + EA I
Sbjct: 619 VKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG--QFD 676
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ K + +IT++ ENG+L FL L+ M IA G+
Sbjct: 677 HPNIIRLEGVVTKSR----PVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGM 732
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + HRDL ++NILV SNL C + D GL+ + +D+ D T+ +
Sbjct: 733 KYL--------AEMNYVHRDLAARNILVNSNLVCKVSDFGLS--RYLQDDTSDPTYTSSL 782
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SDV+S+G+ +WE+
Sbjct: 783 GGKIPVRWTAPEAI----AYRKFT--SASDVWSYGIHMWEV 817
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 76.2 bits (179), Expect = 2e-13
Identities = 59/204 (28%), Positives = 97/204 (47%), Gaps = 30/204 (14%)
Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN 244
IG+G FG V +G + G+ VAVK F + T M +HEN++ +
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM-QHENLVRLLGVILHQG 299
Query: 245 GTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
L+++ ++ G+L +FL + +++ L++ SL +A G+ +L
Sbjct: 300 -----LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLE--------SK 346
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
+ HRDL ++NILV +L + D GLA DS +P ++ APE L
Sbjct: 347 KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLP-------VKWTAPEALKHG 399
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEM 385
T +SDV+SFG++LWE+
Sbjct: 400 KFT------SKSDVWSFGVLLWEV 417
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 76.2 bits (179), Expect = 2e-13
Identities = 59/204 (28%), Positives = 97/204 (47%), Gaps = 30/204 (14%)
Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN 244
IG+G FG V +G + G+ VAVK F + T M +HEN++ +
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM-QHENLVRLLGVILHQG 299
Query: 245 GTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
L+++ ++ G+L +FL + +++ L++ SL +A G+ +L
Sbjct: 300 -----LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLE--------SK 346
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
+ HRDL ++NILV +L + D GLA DS +P ++ APE L
Sbjct: 347 KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLP-------VKWTAPEALKHG 399
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEM 385
T +SDV+SFG++LWE+
Sbjct: 400 KFT------SKSDVWSFGVLLWEV 417
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 76.2 bits (179), Expect = 2e-13
Identities = 70/217 (32%), Positives = 107/217 (49%), Gaps = 39/217 (17%)
Query: 184 IIGKGRFGEVWRGRWRGEN------VAVKI----FSSREECSWFREAEIYQTVMLRHENI 233
+IG G FGEV++G + + VA+K ++ ++ + EA I H NI
Sbjct: 618 VIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMG--QFSHHNI 675
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTL--IKMSLSIATGLAHL- 290
+ +K + + +IT+Y ENG+L FL K + + L + M IA G+ +L
Sbjct: 676 IRLEGVISK----YKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLA 731
Query: 291 HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG-- 348
+M+ V HRDL ++NILV SNL C + D GL+ V D + T G
Sbjct: 732 NMNYV---------HRDLAARNILVNSNLVCKVSDFGLS---RVLEDDPEATYTTSGGKI 779
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
R+ APE + R+F SDV+SFG+V+WE+
Sbjct: 780 PIRWTAPEAI----SYRKFT--SASDVWSFGIVMWEV 810
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 76.2 bits (179), Expect = 2e-13
Identities = 70/217 (32%), Positives = 107/217 (49%), Gaps = 39/217 (17%)
Query: 184 IIGKGRFGEVWRGRWRGEN------VAVKI----FSSREECSWFREAEIYQTVMLRHENI 233
+IG G FGEV++G + + VA+K ++ ++ + EA I H NI
Sbjct: 618 VIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMG--QFSHHNI 675
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTL--IKMSLSIATGLAHL- 290
+ +K + + +IT+Y ENG+L FL K + + L + M IA G+ +L
Sbjct: 676 IRLEGVISK----YKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLA 731
Query: 291 HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG-- 348
+M+ V HRDL ++NILV SNL C + D GL+ V D + T G
Sbjct: 732 NMNYV---------HRDLAARNILVNSNLVCKVSDFGLS---RVLEDDPEATYTTSGGKI 779
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
R+ APE + R+F SDV+SFG+V+WE+
Sbjct: 780 PIRWTAPEAI----SYRKFT--SASDVWSFGIVMWEV 810
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 76.2 bits (179), Expect = 2e-13
Identities = 59/204 (28%), Positives = 97/204 (47%), Gaps = 30/204 (14%)
Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN 244
IG+G FG V +G + G+ VAVK F + T M +HEN++ +
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM-QHENLVRLLGVILHQG 299
Query: 245 GTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
L+++ ++ G+L +FL + +++ L++ SL +A G+ +L
Sbjct: 300 -----LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLE--------SK 346
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
+ HRDL ++NILV +L + D GLA DS +P ++ APE L
Sbjct: 347 KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLP-------VKWTAPEALKHG 399
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEM 385
T +SDV+SFG++LWE+
Sbjct: 400 KFT------SKSDVWSFGVLLWEV 417
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 76.2 bits (179), Expect = 2e-13
Identities = 59/204 (28%), Positives = 97/204 (47%), Gaps = 30/204 (14%)
Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN 244
IG+G FG V +G + G+ VAVK F + T M +HEN++ +
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM-QHENLVRLLGVILHQG 299
Query: 245 GTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
L+++ ++ G+L +FL + +++ L++ SL +A G+ +L
Sbjct: 300 -----LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLE--------SK 346
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
+ HRDL ++NILV +L + D GLA DS +P ++ APE L
Sbjct: 347 KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLP-------VKWTAPEALKHG 399
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEM 385
T +SDV+SFG++LWE+
Sbjct: 400 KFT------SKSDVWSFGVLLWEV 417
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 76.2 bits (179), Expect = 2e-13
Identities = 70/217 (32%), Positives = 107/217 (49%), Gaps = 39/217 (17%)
Query: 184 IIGKGRFGEVWRGRWRGEN------VAVKI----FSSREECSWFREAEIYQTVMLRHENI 233
+IG G FGEV++G + + VA+K ++ ++ + EA I H NI
Sbjct: 618 VIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDFLGEAGIMG--QFSHHNI 675
Query: 234 LGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNTL--IKMSLSIATGLAHL- 290
+ +K + + +IT+Y ENG+L FL K + + L + M IA G+ +L
Sbjct: 676 IRLEGVISK----YKPMMIITEYMENGALDKFLREKDGEFSVLQLVGMLRGIAAGMKYLA 731
Query: 291 HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVG-- 348
+M+ V HRDL ++NILV SNL C + D GL+ V D + T G
Sbjct: 732 NMNYV---------HRDLAARNILVNSNLVCKVSDFGLS---RVLEDDPEATYTTSGGKI 779
Query: 349 TKRYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
R+ APE + R+F SDV+SFG+V+WE+
Sbjct: 780 PIRWTAPEAI----SYRKFT--SASDVWSFGIVMWEV 810
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 76.2 bits (179), Expect = 2e-13
Identities = 59/204 (28%), Positives = 97/204 (47%), Gaps = 30/204 (14%)
Query: 185 IGKGRFGEVWRGRWRGENVAVKIFSSREECSWFREAEIYQTVMLRHENILGFIAADNKDN 244
IG+G FG V +G + G+ VAVK F + T M +HEN++ +
Sbjct: 241 IGEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKM-QHENLVRLLGVILHQG 299
Query: 245 GTWTQLWLITDYHENGSLFDFLTAKS---IDSNTLIKMSLSIATGLAHLHMDIVGTKGKP 301
L+++ ++ G+L +FL + +++ L++ SL +A G+ +L
Sbjct: 300 -----LYIVMEHVSKGNLVNFLRTRGRALVNTAQLLQFSLHVAEGMEYLE--------SK 346
Query: 302 AIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRVGTKRYMAPEVLDET 361
+ HRDL ++NILV +L + D GLA DS +P ++ APE L
Sbjct: 347 KLVHRDLAARNILVSEDLVAKVSDFGLAKAERKGLDSSRLP-------VKWTAPEALKHG 399
Query: 362 MDTRQFDPYKRSDVYSFGLVLWEM 385
T +SDV+SFG++LWE+
Sbjct: 400 KFT------SKSDVWSFGVLLWEV 417
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 672
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 673 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 729 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 778
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 779 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 813
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 679
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 680 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 736 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 784
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 785 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 820
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 605 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 662
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 663 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 718
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 719 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 767
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 768 LGGKFPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 803
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 113 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 170
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 171 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 226
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 227 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 275
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 276 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 311
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 673
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 674 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 730 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 778
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 779 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 814
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 672
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 673 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 729 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 778
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 779 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 813
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 473 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 530
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 531 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 586
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 587 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 636
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 637 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 671
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 672
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 673 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 729 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 778
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 779 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 813
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 672
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 673 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 729 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 778
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 779 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 813
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 679
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 680 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 736 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 784
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 785 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 820
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 673
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 674 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 730 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 778
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 779 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 814
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 679
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 680 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 736 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 784
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 785 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 820
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 622 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 679
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 680 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 735
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 736 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 784
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 785 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 820
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 616 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 673
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 674 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 729
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 730 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 778
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 779 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 814
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 75.4 bits (177), Expect = 4e-13
Identities = 66/221 (29%), Positives = 106/221 (47%), Gaps = 36/221 (16%)
Query: 179 IQLVDIIGKGRFGEVWRGRWRGEN-----VAVKI----FSSREECSWFREAEIYQTVMLR 229
+++ ++IG G FGEV RGR + VA+K ++ R+ + EA I
Sbjct: 615 VKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIMG--QFE 672
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H NI+ + ++T++ ENG+L FL L+ M IA+G+
Sbjct: 673 HPNIIRLEGVVTNS----MPVMILTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIASGM 728
Query: 288 AHLHMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNRV 347
+L + + HRDL ++NILV SNL C + D GL+ + +S D T+ +
Sbjct: 729 RYL--------AEMSYVHRDLAARNILVNSNLVCKVSDFGLS--RFLEENSSDPTYTSSL 778
Query: 348 GTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
G K R+ APE + R+F SD +S+G+V+WE+
Sbjct: 779 GGKIPIRWTAPEAI----AFRKFT--SASDAWSYGIVMWEV 813
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 75.4 bits (177), Expect = 4e-13
Identities = 71/222 (31%), Positives = 108/222 (48%), Gaps = 38/222 (17%)
Query: 179 IQLVDIIGKGRFGEVWRGRWR--GEN---VAVKIFSS----REECSWFREAEIYQTVMLR 229
+++ +IG G FGEV G + G+ VA+K S ++ + EA I
Sbjct: 621 VKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMG--QFD 678
Query: 230 HENILGFIAADNKDNGTWTQLWLITDYHENGSLFDFLTAKSIDSNT--LIKMSLSIATGL 287
H N++ K T + +IT++ ENGSL FL L+ M IA G+
Sbjct: 679 HPNVIHLEGVVTKS----TPVMIITEFMENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGM 734
Query: 288 AHL-HMDIVGTKGKPAIAHRDLKSKNILVKSNLSCVIGDLGLAVRHNVSNDSVDVPSTNR 346
+L M+ V HRDL ++NILV SNL C + D GL+ + +D+ D T+
Sbjct: 735 KYLADMNYV---------HRDLAARNILVNSNLVCKVSDFGLS--RFLEDDTSDPTYTSA 783
Query: 347 VGTK---RYMAPEVLDETMDTRQFDPYKRSDVYSFGLVLWEM 385
+G K R+ APE + R+F SDV+S+G+V+WE+
Sbjct: 784 LGGKIPIRWTAPEAI----QYRKFT--SASDVWSYGIVMWEV 819
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.136 0.441
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 82,402,042
Number of Sequences: 224733
Number of extensions: 3768828
Number of successful extensions: 14935
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 517
Number of HSP's successfully gapped in prelim test: 1853
Number of HSP's that attempted gapping in prelim test: 11288
Number of HSP's gapped (non-prelim): 2888
length of query: 477
length of database: 73,234,838
effective HSP length: 93
effective length of query: 384
effective length of database: 52,334,669
effective search space: 20096512896
effective search space used: 20096512896
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)
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