Silkworm BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000600-TA|BGIBMGA000600-PA|IPR008973|C2
calcium/lipid-binding region, CaLB, IPR002048|Calcium-binding EF-hand,
IPR000008|C2 calcium-dependent membrane targeting, IPR000980|SH2
motif, IPR001452|Src homology-3,
IPR000909|Phosphatidylinositol-specific phospholipase C, X region,
IPR001711|Phosphatidylinositol-specific phospholipase C, Y domain,
IPR001849|Pleckstrin-like, IPR001192|Phosphoinositide-specific
phospholipase C, C-terminal (PLC),
IPR013841|Phosphatidylinositol-specific phospholipase C, X and Y boxes
         (1201 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholi...  1141   0.0  
DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma ...  1141   0.0  
AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma ...  1141   0.0  
AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma ...  1141   0.0  
AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein p...  1141   0.0  
BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein.       962   0.0  
BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein.       962   0.0  
BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein.       962   0.0  
BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein.       962   0.0  
AB208914-1|BAD92151.1| 1278|Homo sapiens 1-phosphatidylinositol-...   957   0.0  
X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for ...   947   0.0  
M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein.                  947   0.0  
AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2...   947   0.0  
DQ176850-1|ABA12209.1| 1416|Homo sapiens phospholipase C-eta2 pr...   248   9e-65
AB007919-1|BAA32295.3| 1182|Homo sapiens KIAA0450 protein protein.    248   9e-65
AK122589-1|BAC56930.1| 1129|Homo sapiens FLJ00414 protein protein.    245   9e-64
BC113950-1|AAI13951.1| 1655|Homo sapiens phospholipase C, eta 1 ...   244   2e-63
AY691171-1|AAW22608.1| 1693|Homo sapiens phospholipase C-eta1b p...   244   2e-63
AY691170-1|AAW22607.1| 1002|Homo sapiens phospholipase C-eta1a p...   244   2e-63
BC006355-1|AAH06355.1|  762|Homo sapiens phospholipase C, delta ...   237   2e-61
AK223203-1|BAD96923.1|  762|Homo sapiens phospholipase C, delta ...   236   3e-61
AB209862-1|BAD93099.1|  776|Homo sapiens Phospholipase C, delta ...   232   5e-60
BC050382-1|AAH50382.2|  756|Homo sapiens phospholipase C, delta ...   231   9e-60
BC072384-1|AAH72384.1|  789|Homo sapiens phospholipase C, delta ...   231   1e-59
AK074240-1|BAB85029.1|  789|Homo sapiens protein ( Homo sapiens ...   231   1e-59
AB075844-1|BAB85550.1|  757|Homo sapiens KIAA1964 protein protein.    231   1e-59
U09117-1|AAA73567.1|  756|Homo sapiens phospholipase c delta 1 p...   231   2e-59
BC128207-1|AAI28208.1| 1032|Homo sapiens PLCH2 protein protein.       230   3e-59
D42108-1|BAA07688.1|  997|Homo sapiens Phospholipase C protein.       216   5e-55
BC043358-1|AAH43358.1| 1238|Homo sapiens PLCH2 protein protein.       216   5e-55
BC111985-1|AAI11986.1|  997|Homo sapiens phospholipase C-like 1 ...   215   6e-55
BC101531-1|AAI01532.1|  997|Homo sapiens phospholipase C-like 1 ...   215   6e-55
BC036392-1|AAH36392.1| 1001|Homo sapiens phospholipase C-like 2 ...   211   1e-53
AB029015-1|BAA83044.1| 1154|Homo sapiens KIAA1092 protein protein.    211   1e-53
BC010668-1|AAH10668.2|  617|Homo sapiens PLCD3 protein protein.       210   2e-53
AK074149-1|BAB84975.1|  656|Homo sapiens FLJ00222 protein protein.    204   1e-51
BC125067-1|AAI25068.1|  415|Homo sapiens PLCZ1 protein protein.       196   3e-49
AK097725-1|BAC05152.1|  390|Homo sapiens protein ( Homo sapiens ...   196   3e-49
AK022610-1|BAB14129.1|  466|Homo sapiens protein ( Homo sapiens ...   196   3e-49
AF532185-1|AAN71895.1|  608|Homo sapiens PLC-zeta protein.            196   3e-49
AB028992-1|BAA83021.1|  787|Homo sapiens KIAA1069 protein protein.    196   3e-49
AK023546-1|BAB14606.1|  677|Homo sapiens protein ( Homo sapiens ...   196   4e-49
AY035866-1|AAK61372.1|  504|Homo sapiens testis-development rela...   194   1e-48
BC117458-1|AAI17459.1| 1175|Homo sapiens phospholipase C, beta 4...   180   4e-44
AL031652-3|CAI42218.2| 1194|Homo sapiens phospholipase C, beta 4...   180   4e-44
AL031652-2|CAI42213.1| 1175|Homo sapiens phospholipase C, beta 4...   180   4e-44
AL023805-6|CAI43092.2| 1194|Homo sapiens phospholipase C, beta 4...   180   4e-44
AL023805-5|CAI43087.1| 1175|Homo sapiens phospholipase C, beta 4...   180   4e-44
AL031652-4|CAI42214.1| 1023|Homo sapiens phospholipase C, beta 4...   173   4e-42
AL023805-7|CAI43088.1| 1023|Homo sapiens phospholipase C, beta 4...   173   4e-42
L41349-1|AAB02027.1| 1022|Homo sapiens phospholipase C beta 4 pr...   172   7e-42
AL389885-3|CAH73289.1| 1994|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL389885-2|CAH73288.1| 2312|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL365510-3|CAH73758.1| 1994|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL365510-2|CAH73757.1| 2312|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL139124-2|CAI16675.1| 1994|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL139124-1|CAI16674.1| 2312|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL139118-2|CAH70740.1| 1994|Homo sapiens phospholipase C, epsilo...   167   3e-40
AL139118-1|CAH70739.1| 2312|Homo sapiens phospholipase C, epsilo...   167   3e-40
AF170071-1|AAG28341.1| 1994|Homo sapiens phospholipase C epsilon...   167   3e-40
AF117948-1|AAF22005.1| 1103|Homo sapiens pancreas-enriched phosp...   167   3e-40
AB040949-1|BAA96040.2| 2304|Homo sapiens KIAA1516 protein protein.    167   3e-40
BC117231-1|AAI17232.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
BC069420-1|AAH69420.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AY004175-1|AAF86613.1| 1211|Homo sapiens phospholipase C beta 1 ...   165   1e-39
AL137267-1|CAB70666.1|  913|Homo sapiens hypothetical protein pr...   165   1e-39
AL050323-3|CAI22831.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL050323-2|CAI22830.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL050315-2|CAI42239.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL050315-1|CAI42238.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL049632-2|CAI43152.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL049632-1|CAI43151.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL049593-1|CAI22175.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL034551-2|CAI21974.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL034551-1|CAI21973.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL031683-3|CAI43122.1| 1173|Homo sapiens phospholipase C, beta 1...   165   1e-39
AL031683-2|CAI43121.1| 1216|Homo sapiens phospholipase C, beta 1...   165   1e-39
AK023689-1|BAB14641.1|  639|Homo sapiens protein ( Homo sapiens ...   165   1e-39
AJ278314-1|CAB98143.1| 1173|Homo sapiens phospholipase C-beta-1b...   165   1e-39
AJ278313-1|CAB98142.1| 1216|Homo sapiens phospholipase C-beta-1a...   165   1e-39
AB011153-1|BAA25507.3| 1218|Homo sapiens KIAA0581 protein protein.    165   1e-39
AF190642-1|AAG17145.2| 2303|Homo sapiens phosphoinositide-specif...   164   2e-39
AK097555-1|BAC05099.1|  403|Homo sapiens protein ( Homo sapiens ...   161   1e-38
AB209599-1|BAD92836.1|  279|Homo sapiens phospholipase C, delta ...   159   6e-38
Z37544-1|CAA85776.1| 1234|Homo sapiens phospholipase C beta 3 pr...   156   5e-37
Z16411-1|CAA78903.1| 1051|Homo sapiens phospholipase c protein.       156   5e-37
U26425-1|AAA77683.1| 1234|Homo sapiens phospholipase C-beta-3 pr...   156   5e-37
BC032659-1|AAH32659.1| 1191|Homo sapiens Similar to phospholipas...   156   5e-37
M95678-1|AAA36453.1| 1181|Homo sapiens phospholipase C-beta-2 pr...   151   1e-35
AB209583-1|BAD92820.1|  901|Homo sapiens phospholipase C, beta 2...   151   1e-35
AK022543-1|BAB14090.1|  806|Homo sapiens protein ( Homo sapiens ...   145   1e-33
BC019679-1|AAH19679.1|  716|Homo sapiens PLCH2 protein protein.       130   3e-29
AL591042-2|CAI14458.1|  753|Homo sapiens vav 3 oncogene protein.       94   3e-18
AL591042-1|CAI14457.1|  847|Homo sapiens vav 3 oncogene protein.       94   3e-18
AL513206-2|CAH73196.1|  753|Homo sapiens vav 3 oncogene protein.       94   3e-18
AL513206-1|CAH73195.1|  847|Homo sapiens vav 3 oncogene protein.       94   3e-18
AL391235-1|CAH72458.1|  847|Homo sapiens vav 3 oncogene protein.       94   3e-18
AL353892-1|CAI21786.1|  847|Homo sapiens vav 3 oncogene protein.       94   3e-18
AF118887-1|AAD20349.1|  847|Homo sapiens VAV-3 protein protein.        94   3e-18
AF118886-1|AAD20348.1|  753|Homo sapiens VAV-3 protein beta isof...    94   3e-18
AF067817-1|AAC79695.1|  847|Homo sapiens VAV-3 protein protein.        94   3e-18
BC013361-1|AAH13361.2|  790|Homo sapiens VAV1 protein protein.         93   7e-18
AF030227-1|AAC25011.1|  845|Homo sapiens vav protein protein.          93   7e-18
X83931-1|CAA58783.1|  539|Homo sapiens VAV protein.                    92   1e-17
BX537442-1|CAD97684.1|  355|Homo sapiens hypothetical protein pr...    90   5e-17
X70766-1|CAA50045.1|  593|Homo sapiens protein-tyrosine phosphat...    89   9e-17
L07527-1|AAA17022.1|  593|Homo sapiens protein-tyrosine phosphat...    89   9e-17
L03535-1|AAA36611.1|  593|Homo sapiens phosphotyrosyl-protein ph...    89   9e-17
D13540-1|BAA02740.2|  593|Homo sapiens protein-tyrosine phosphat...    89   9e-17
BT007106-1|AAP35770.1|  460|Homo sapiens protein tyrosine phosph...    89   9e-17
BC008692-1|AAH08692.1|  460|Homo sapiens PTPN11 protein protein.       89   9e-17
X16316-1|CAA34383.1|  797|Homo sapiens VAV protein.                    88   2e-16
BX640754-1|CAE45861.1|  801|Homo sapiens hypothetical protein pr...    85   2e-15
BC132967-1|AAI32968.1|  839|Homo sapiens vav 2 oncogene protein.       85   2e-15
BC132965-1|AAI32966.1|  839|Homo sapiens vav 2 oncogene protein.       85   2e-15
BC128448-1|AAI28449.1|  474|Homo sapiens VAV2 protein protein.         85   2e-15
BC033187-1|AAH33187.1|  369|Homo sapiens VAV2 protein protein.         85   2e-15
AL590710-5|CAI12280.1|  839|Homo sapiens vav 2 oncogene protein.       85   2e-15
AL445931-1|CAI13724.1|  839|Homo sapiens vav 2 oncogene protein.       85   2e-15
AL357934-1|CAI15782.1|  839|Homo sapiens vav 2 oncogene protein.       85   2e-15
X62852-1|CAA44664.1|  160|Homo sapiens ash protein protein.            83   4e-15
M96995-1|AAA58448.1|  217|Homo sapiens epidermal growth factor r...    83   4e-15
CR541942-1|CAG46740.1|  217|Homo sapiens GRB2 protein.                 83   4e-15
BC000631-1|AAH00631.1|  217|Homo sapiens growth factor receptor-...    83   4e-15
AF498925-1|AAM21073.1|  217|Homo sapiens growth factor receptor-...    83   4e-15
AF063618-1|AAC72075.1|  217|Homo sapiens growth factor receptor-...    83   4e-15
U52518-1|AAC50541.1|  217|Homo sapiens Grb2-related adaptor prot...    81   3e-14
CR541966-1|CAG46764.1|  217|Homo sapiens GRAP protein.                 81   3e-14
CR541941-1|CAG46739.1|  217|Homo sapiens GRAP protein.                 81   3e-14
CR450363-1|CAG29359.1|  217|Homo sapiens GRB2 protein.                 81   3e-14
BT019981-1|AAV38784.1|  217|Homo sapiens GRB2-related adaptor pr...    81   3e-14
BC063035-1|AAH63035.1|  217|Homo sapiens GRB2-related adaptor pr...    81   3e-14
BC035856-1|AAH35856.1|  217|Homo sapiens GRB2-related adaptor pr...    81   3e-14
S76992-1|AAB34377.1|  878|Homo sapiens VAV2 protein.                   80   5e-14
AL590710-7|CAI12279.1|  878|Homo sapiens vav 2 oncogene protein.       80   5e-14
AL590710-6|CAI12278.1|  868|Homo sapiens vav 2 oncogene protein.       80   5e-14
AL445931-3|CAI13723.1|  868|Homo sapiens vav 2 oncogene protein.       80   5e-14
AL445931-2|CAI13722.1|  878|Homo sapiens vav 2 oncogene protein.       80   5e-14
AL357934-3|CAI15781.1|  868|Homo sapiens vav 2 oncogene protein.       80   5e-14
AL357934-2|CAI15783.1|  878|Homo sapiens vav 2 oncogene protein.       80   5e-14
AK122591-1|BAC56932.1|  600|Homo sapiens FLJ00417 protein protein.     80   5e-14
AY512961-1|AAS82574.1|  272|Homo sapiens truncated phospholipase...    72   1e-11
X62055-1|CAA43982.1|  597|Homo sapiens protein-tyrosine  phospha...    72   1e-11
U47924-18|AAB51323.1|  595|Homo sapiens protein tyrosine phospha...    72   1e-11
M74903-1|AAA35963.1|  595|Homo sapiens hematopoietic cell phopha...    72   1e-11
BT007390-1|AAP36054.1|  597|Homo sapiens protein tyrosine phosph...    72   1e-11
BC007667-1|AAH07667.1|  597|Homo sapiens protein tyrosine phosph...    72   1e-11
BC002523-1|AAH02523.1|  597|Homo sapiens protein tyrosine phosph...    72   1e-11
AK223629-1|BAD97349.1|  595|Homo sapiens protein tyrosine phosph...    72   1e-11
AB079851-2|BAC81775.1|  595|Homo sapiens protein tyrosine phosph...    72   1e-11
AB079851-1|BAC81774.1|  597|Homo sapiens protein tyrosine phosph...    72   1e-11
M77273-1|AAA36610.1|  595|Homo sapiens tyrosine phosphatase prot...    71   2e-11
AF178946-1|AAD53317.1|  624|Homo sapiens 70 kDa SHP-1L protein p...    71   2e-11
BC007195-1|AAH07195.1|  380|Homo sapiens NCK adaptor protein 2 p...    69   1e-10
BC000103-1|AAH00103.1|  380|Homo sapiens NCK adaptor protein 2 p...    69   1e-10
AF047487-1|AAC80284.1|  380|Homo sapiens Nck-2 protein.                69   1e-10
AC009505-1|AAY24332.1|  304|Homo sapiens unknown protein.              69   1e-10
X17576-1|CAA35599.1|  377|Homo sapiens protein ( Human melanoma ...    68   2e-10
M23612-1|AAA35865.1|  870|Homo sapiens GTPase-activating protein...    68   2e-10
BC054891-1|AAH54891.1|  313|Homo sapiens RASA1 protein protein.        68   2e-10
BC020761-1|AAH20761.1|  317|Homo sapiens Unknown (protein for IM...    68   2e-10
BC006403-1|AAH06403.1|  377|Homo sapiens NCK adaptor protein 1 p...    68   2e-10
M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein...    68   2e-10
BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activat...    68   2e-10
AB209106-1|BAD92343.1|  871|Homo sapiens RAS p21 protein activat...    68   2e-10
AF043119-1|AAC04831.1|  381|Homo sapiens SH2/SH3 adaptor protein...    67   3e-10
U15528-2|AAA82880.1|  595|Homo sapiens protein tyrosine phosphat...    67   4e-10
BC128208-1|AAI28209.1|  368|Homo sapiens PLCH2 protein protein.        67   4e-10
U34379-1|AAB60412.1|  527|Homo sapiens tyrosine kinase protein.        65   2e-09
L27071-1|AAA74557.1|  527|Homo sapiens tyrosine kinase protein.        65   2e-09
BC012924-1|AAH12924.1|  280|Homo sapiens DAPP1 protein protein.        65   2e-09
AF186022-1|AAF14578.1|  280|Homo sapiens B lymphocyte adapter pr...    65   2e-09
AF178987-1|AAF44351.1|  280|Homo sapiens protein-tyrosine phosph...    65   2e-09
AF163254-1|AAD49697.1|  280|Homo sapiens adaptor protein DAPP1 p...    65   2e-09
BC008799-1|AAH08799.1|  513|Homo sapiens cortactin protein.            64   2e-09
AK222613-1|BAD96333.1|  550|Homo sapiens cortactin isoform a var...    64   2e-09
AK027488-1|BAB55148.1|  426|Homo sapiens protein ( Homo sapiens ...    64   2e-09
AF227968-1|AAF73913.1|  671|Homo sapiens SH2-B beta signaling pr...    64   2e-09
AB037720-1|BAA92537.1|  730|Homo sapiens KIAA1299 protein protein.     64   2e-09
BC010704-1|AAH10704.1|  426|Homo sapiens SH2B1 protein protein.        64   4e-09
M98343-1|AAA58455.1|  550|Homo sapiens amplaxin protein.               63   5e-09
DQ402497-1|ABD62889.1|  478|Homo sapiens nostrin protein.              63   7e-09
BC093072-1|AAH93072.1|  506|Homo sapiens nitric oxide synthase t...    63   7e-09
BC014189-1|AAH14189.1|  428|Homo sapiens nitric oxide synthase t...    63   7e-09
AK002203-1|BAE46614.1|  506|Homo sapiens protein ( Homo sapiens ...    63   7e-09
AJ532842-1|CAD58724.1|  506|Homo sapiens NOSTRIN protein protein.      63   7e-09
Z82206-3|CAI42713.1|  330|Homo sapiens GRB2-related adaptor prot...    62   2e-08
Y18051-1|CAA77021.1|  330|Homo sapiens GADS protein protein.           62   2e-08
CR541849-1|CAG46647.1|  330|Homo sapiens GRAP2 protein.                62   2e-08
CR536524-1|CAG38761.1|  330|Homo sapiens GRAP2 protein.                62   2e-08
CR456498-1|CAG30384.1|  330|Homo sapiens GRAP2 protein.                62   2e-08
BC026002-1|AAH26002.1|  330|Homo sapiens GRAP2 protein protein.        62   2e-08
BC025692-1|AAH25692.1|  330|Homo sapiens GRB2-related adaptor pr...    62   2e-08
AY069959-1|AAL58573.1|  330|Homo sapiens Mona protein.                 62   2e-08
AL049924-1|CAB43208.1|  540|Homo sapiens hypothetical protein pr...    62   2e-08
AJ011736-1|CAA09757.1|  330|Homo sapiens growth factor receptor ...    62   2e-08
AF236120-1|AAF60320.1|  330|Homo sapiens adapter protein GRID pr...    62   2e-08
AF236119-1|AAF60319.1|  330|Homo sapiens adapter protein GRID pr...    62   2e-08
AF227969-1|AAF73914.1|  683|Homo sapiens SH2-B gamma signaling p...    62   2e-08
AF129476-1|AAD41782.1|  330|Homo sapiens hematopoietic cell-asso...    62   2e-08
AF121002-1|AAF31758.1|  330|Homo sapiens SH3-SH2-SH3 adaptor pro...    62   2e-08
AF102694-1|AAD04926.1|  330|Homo sapiens Grb2-related adaptor pr...    62   2e-08
AF090456-1|AAD13027.1|  330|Homo sapiens Grb-2-like protein prot...    62   2e-08
AF042380-1|AAC69273.1|  330|Homo sapiens Grf40 adaptor protein p...    62   2e-08
AF227967-1|AAF73912.1|  756|Homo sapiens SH2-B alpha signaling p...    61   3e-08
BC031687-1|AAH31687.1|  430|Homo sapiens drebrin-like protein.         60   4e-08
BC011677-1|AAH11677.1|  431|Homo sapiens drebrin-like protein.         60   4e-08
AK027367-1|BAB55065.1|  439|Homo sapiens protein ( Homo sapiens ...    60   4e-08
AF250287-1|AAF81273.1|  430|Homo sapiens cervical SH3P7 protein.       60   4e-08
AF218020-1|AAG17262.2|  430|Homo sapiens unknown protein.              60   4e-08
AF197060-1|AAF13701.1|  430|Homo sapiens src homology 3 domain-c...    60   4e-08
AF151364-1|AAG13120.1|  430|Homo sapiens mucin-associated protei...    60   4e-08
AF077353-1|AAF80228.1|  430|Homo sapiens drebrin F protein.            60   4e-08
AB209486-1|BAD92723.1|  358|Homo sapiens Drebrin-like protein va...    60   4e-08
X59656-1|CAA42199.1|  303|Homo sapiens CRKL protein.                   60   5e-08
CR456423-1|CAG30309.1|  303|Homo sapiens CRKL protein.                 60   5e-08
BC043500-1|AAH43500.1|  303|Homo sapiens v-crk sarcoma virus CT1...    60   5e-08
AC069137-1|AAY24097.1|  392|Homo sapiens unknown protein.              60   5e-08
AL121829-14|CAC15526.1|  488|Homo sapiens protein ( Human DNA se...    60   6e-08
CR457167-1|CAG33448.1|  430|Homo sapiens HIP-55 protein.               59   8e-08
U09812-1|AAA78806.1|   59|Homo sapiens protein ( Human phospholi...    58   1e-07
D25304-1|BAA04985.1|  773|Homo sapiens KIAA0006 protein.               58   3e-07
BC043505-1|AAH43505.1|  538|Homo sapiens ARHGEF6 protein protein.      58   3e-07
BC039856-1|AAH39856.1|  776|Homo sapiens Rac/Cdc42 guanine nucle...    58   3e-07
AM491363-1|CAM33013.1|  498|Homo sapiens bcr-abl1 e19a2 chimeric...    58   3e-07
AL683813-1|CAI39443.1|  776|Homo sapiens Rac/Cdc42 guanine nucle...    58   3e-07
AL135783-5|CAI42903.1|  622|Homo sapiens Rac/Cdc42 guanine nucle...    58   3e-07
AL135783-1|CAI42899.1|  776|Homo sapiens Rac/Cdc42 guanine nucle...    58   3e-07
X16663-1|CAA34651.1|  486|Homo sapiens protein ( Human HS1 gene ...    57   3e-07
BT006824-1|AAP35470.1|  486|Homo sapiens hematopoietic cell-spec...    57   3e-07
BC016758-1|AAH16758.1|  486|Homo sapiens hematopoietic cell-spec...    57   3e-07
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN...    57   4e-07
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p...    57   4e-07
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p...    57   4e-07
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le...    57   4e-07
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le...    57   4e-07
BC053878-1|AAH53878.1|  619|Homo sapiens zeta-chain (TCR) associ...    57   4e-07
BC039039-1|AAH39039.1|  493|Homo sapiens ZAP70 protein protein.        57   4e-07
AM491362-1|CAM33012.1|  585|Homo sapiens bcr-abl1 e6a2 chimeric ...    57   4e-07
AM491361-1|CAM33011.1|  313|Homo sapiens bcr-abl1 e1a3 chimeric ...    57   4e-07
AM491360-1|CAM33010.1|  260|Homo sapiens bcr-abl1 e14a3 chimeric...    57   4e-07
AM491359-1|CAM33009.1|  235|Homo sapiens bcr-abl1 e13a3 chimeric...    57   4e-07
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l...    57   4e-07
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le...    57   4e-07
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le...    57   4e-07
AJ131467-1|CAA10377.1|  307|Homo sapiens BCR/ABL chimeric fusion...    57   4e-07
AJ131466-1|CAA10376.1|  332|Homo sapiens BCR/ABL (major breakpoi...    57   4e-07
AF113911-1|AAD04633.1|  359|Homo sapiens BCR-ABL minor breakpoin...    57   4e-07
AC016699-1|AAX93187.1|  493|Homo sapiens unknown protein.              57   4e-07
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le...    57   4e-07
CR456794-1|CAG33075.1|  486|Homo sapiens HCLS1 protein.                56   6e-07
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ...    56   8e-07
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le...    56   8e-07
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr...    56   8e-07
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.         56   8e-07
BC050663-1|AAH50663.1|  381|Homo sapiens SH3KBP1 protein protein.      56   8e-07
BC015806-1|AAH15806.1|  665|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AY542305-1|AAT08174.1|  665|Homo sapiens GIG10 protein.                56   8e-07
AY423734-1|AAS00497.1|  665|Homo sapiens migration-inducing gene...    56   8e-07
AL772197-2|CAH71710.1|  665|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL772197-1|CAH71709.1|  553|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL732423-3|CAI40276.1|  665|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL732327-2|CAI40510.1|  665|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL732327-1|CAI40509.1|  553|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL732325-2|CAI41253.1|  665|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL732325-1|CAI41252.1|  553|Homo sapiens SH3-domain kinase bindi...    56   8e-07
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le...    56   8e-07
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le...    56   8e-07
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le...    56   8e-07
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le...    56   8e-07
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le...    56   8e-07
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le...    56   8e-07
AF230904-1|AAF37854.1|  665|Homo sapiens c-Cbl-interacting prote...    56   8e-07
K03218-1|AAA60584.1|  536|Homo sapiens SRC protein.                    56   1e-06
BC051270-1|AAH51270.2|  536|Homo sapiens v-src sarcoma (Schmidt-...    56   1e-06
BC011566-1|AAH11566.1|  536|Homo sapiens SRC protein protein.          56   1e-06
AL133293-2|CAC10573.1|  542|Homo sapiens v-src sarcoma (Schmidt-...    56   1e-06
AL133293-1|CAC34523.1|  536|Homo sapiens v-src sarcoma (Schmidt-...    56   1e-06
X78549-1|CAA55295.1|  451|Homo sapiens tyrosine kinase protein.        55   1e-06
U61412-1|AAC34935.1|  451|Homo sapiens non-receptor type protein...    55   1e-06
BC035843-1|AAH35843.1|  451|Homo sapiens PTK6 protein tyrosine k...    55   1e-06
BC030815-1|AAH30815.1|  454|Homo sapiens phosphoinositide-3-kina...    55   1e-06
AL121829-13|CAC15525.1|  451|Homo sapiens Ptk6 protein.                55   1e-06
X14055-1|CAA32211.1|  509|Homo sapiens protein ( Human lymphocyt...    55   2e-06
X13529-1|CAA31884.1|  509|Homo sapiens protein ( Human lck mRNA ...    55   2e-06
U23852-1|AAC50287.1|  363|Homo sapiens p56lck protein.                 55   2e-06
U07236-1|AAA18225.1|  512|Homo sapiens lymphocyte-specific prote...    55   2e-06
M36881-1|AAA59502.1|  509|Homo sapiens lymphocyte-specific prote...    55   2e-06
BC094795-1|AAH94795.1|  724|Homo sapiens phosphoinositide-3-kina...    55   2e-06
BC033889-1|AAH33889.1|  634|Homo sapiens CTTN protein protein.         55   2e-06
BC013200-1|AAH13200.1|  539|Homo sapiens LCK protein protein.          55   2e-06
AL121991-3|CAI22321.1|  526|Homo sapiens lymphocyte-specific pro...    55   2e-06
AL121991-2|CAI22320.1|  496|Homo sapiens lymphocyte-specific pro...    55   2e-06
AK223613-1|BAD97333.1|  454|Homo sapiens phosphoinositide-3-kina...    55   2e-06
AJ012793-1|CAB42642.1|  576|Homo sapiens lymphocyte adaptor prot...    55   2e-06
AF279367-1|AAO15359.1|  424|Homo sapiens phosphoinositide 3-kina...    55   2e-06
AF228313-1|AAF34794.1|  496|Homo sapiens tyrosine kinase LCK pro...    55   2e-06
AF055581-1|AAC71695.1|  575|Homo sapiens adaptor protein Lnk pro...    55   2e-06
AB208911-1|BAD92148.1|  439|Homo sapiens lymphocyte adaptor prot...    55   2e-06
AB000520-1|BAA22514.1|  632|Homo sapiens APS protein.                  55   2e-06
X74765-1|CAB58562.1|  450|Homo sapiens protein tyrosine kinase p...    54   2e-06
X60114-1|CAA42713.1|  450|Homo sapiens put. cytoplasmic tyrosine...    54   2e-06
X59932-1|CAA42556.1|  450|Homo sapiens c-src-kinase protein.           54   2e-06
DQ075211-1|AAY57329.1|  450|Homo sapiens c-src tyrosine kinase p...    54   2e-06
CR541960-1|CAG46758.1|  450|Homo sapiens CSK protein.                  54   2e-06
BC106073-1|AAI06074.1|  450|Homo sapiens c-src tyrosine kinase p...    54   2e-06
BC104875-1|AAI04876.1|  450|Homo sapiens c-src tyrosine kinase p...    54   2e-06
BC104847-1|AAI04848.1|  450|Homo sapiens c-src tyrosine kinase p...    54   2e-06
AK223626-1|BAD97346.1|  449|Homo sapiens c-src tyrosine kinase v...    54   2e-06
D88532-1|BAA13636.1|  461|Homo sapiens p55pik protein.                 54   3e-06
BX537388-1|CAD97630.1|  494|Homo sapiens hypothetical protein pr...    54   3e-06
BC082982-1|AAH82982.1|  454|Homo sapiens SH2D4A protein protein.       54   3e-06
BC021622-1|AAH21622.1|  461|Homo sapiens phosphoinositide-3-kina...    54   3e-06
BC014525-1|AAH14525.2|  338|Homo sapiens SH2D4A protein protein.       54   3e-06
AY190323-1|AAO41715.1|  298|Homo sapiens SH2A protein.                 54   3e-06
AL358075-3|CAI21703.1|  402|Homo sapiens phosphoinositide-3-kina...    54   3e-06
AL358075-2|CAI21702.1|  461|Homo sapiens phosphoinositide-3-kina...    54   3e-06
AK024799-1|BAB15010.1|  454|Homo sapiens protein ( Homo sapiens ...    54   3e-06
AF028785-1|AAC39696.1|  402|Homo sapiens phosphatidylinositol 3-...    54   3e-06
U61166-1|AAC50592.1|  520|Homo sapiens SH3 domain-containing pro...    54   4e-06
D63476-1|BAA09763.2|  802|Homo sapiens KIAA0142 protein.               54   4e-06
DQ679757-1|ABG74698.1| 1215|Homo sapiens intersectin 1 short for...    54   4e-06
DQ679756-1|ABG74697.1| 1178|Homo sapiens intersectin 1 short for...    54   4e-06
DQ679755-1|ABG74696.1| 1149|Homo sapiens intersectin 1 short for...    54   4e-06
DQ679754-1|ABG74695.1| 1144|Homo sapiens intersectin 1 short for...    54   4e-06
BC117560-1|AAI17561.1| 1144|Homo sapiens ITSN1 protein protein.        54   4e-06
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma...    54   4e-06
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein.        54   4e-06
BC060776-1|AAH60776.1|  803|Homo sapiens ARHGEF7 protein protein.      54   4e-06
BC050521-1|AAH50521.1|  764|Homo sapiens Rho guanine nucleotide ...    54   4e-06
BC033905-1|AAH33905.1|  753|Homo sapiens ARHGEF7 protein protein.      54   4e-06
AL834228-1|CAD38906.1|  812|Homo sapiens hypothetical protein pr...    54   4e-06
AL390754-5|CAM13628.1|  646|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL390754-4|CAI12463.1|  705|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL390754-2|CAI12461.1|  625|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL390754-1|CAI12460.1|  123|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL139086-4|CAM20788.1|  646|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL139086-3|CAI14672.1|  705|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL139086-2|CAI14671.1|  625|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AL139086-1|CAI14670.1|  123|Homo sapiens Rho guanine nucleotide ...    54   4e-06
AF180522-1|AAD53183.1|  187|Homo sapiens intersectin short form ...    54   4e-06
AF114488-1|AAD29953.1| 1220|Homo sapiens intersectin short isofo...    54   4e-06
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor...    54   4e-06
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p...    54   4e-06
AF064243-1|AAC78610.1| 1220|Homo sapiens intersectin short form ...    54   4e-06
AB177849-1|BAD66827.1|  680|Homo sapiens KIAA0142 splice variant...    54   4e-06
AB177848-1|BAD66826.1|  691|Homo sapiens KIAA0142 splice variant...    54   4e-06
U87166-1|AAC39757.1|  508|Homo sapiens spectrin SH3 domain bindi...    53   5e-06
U22322-1|AAC50116.1|  505|Homo sapiens Rak protein.                    53   5e-06
BC024254-1|AAH24254.1|  476|Homo sapiens abl-interactor 1 protein.     53   5e-06
AL390961-8|CAI17274.1|  476|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-7|CAI17277.1|  480|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-6|CAI17276.1|  481|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-5|CAI17275.1|  508|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-4|CAI17273.1|  475|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-3|CAI17272.1|  446|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-2|CAI17279.1|  451|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL390961-1|CAI17278.1|  452|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-8|CAH73116.1|  452|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-7|CAH73115.1|  476|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-6|CAH73114.1|  480|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-5|CAH73113.1|  481|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-4|CAH73112.1|  508|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-3|CAH73119.1|  475|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-2|CAH73118.1|  446|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AL139404-1|CAH73117.1|  451|Homo sapiens spectrin SH3 domain bin...    53   5e-06
AK024620-1|BAB14935.1|  272|Homo sapiens protein ( Homo sapiens ...    53   5e-06
AJ865079-1|CAI23831.1|  516|Homo sapiens proto-oncogene tyrosine...    53   5e-06
AJ277065-1|CAB88006.1|  508|Homo sapiens spectrin SH3 binding pr...    53   5e-06
AF540955-1|AAN28379.1|  476|Homo sapiens Abl-interactor 1 protein.     53   5e-06
AF260262-1|AAF70309.1|  446|Homo sapiens Abl-interactor protein ...    53   5e-06
AF006516-1|AAB62569.1|  480|Homo sapiens e3B1 protein.                 53   5e-06
AF001628-1|AAD00897.1|  451|Homo sapiens interactor protein AblB...    53   5e-06
AB209268-1|BAD92505.1|  476|Homo sapiens Abl-interactor 1 varian...    53   5e-06
AB040151-1|BAB55675.1|  452|Homo sapiens hNap1 Binding Protein p...    53   5e-06
U00803-1|AAA18284.1|  505|Homo sapiens SRC-like tyrosine kinase ...    53   7e-06
BC012916-1|AAH12916.1|  505|Homo sapiens fyn-related kinase prot...    53   7e-06
AL357141-2|CAI16469.1|  505|Homo sapiens fyn-related kinase prot...    53   7e-06
AL121963-8|CAB87592.2|  505|Homo sapiens fyn-related kinase prot...    53   7e-06
X58957-1|CAA41728.1|  659|Homo sapiens agammaglobulinaemia tyros...    52   9e-06
U78027-4|AAB64205.1|  659|Homo sapiens Bruton's tyrosine kinase ...    52   9e-06
U10087-1|AAB60639.1|  659|Homo sapiens Bruton agammaglobulinemia...    52   9e-06
L76687-1|AAC15861.1|  540|Homo sapiens Grb14 protein.                  52   9e-06
L31572-1|AAA61479.1|  659|Homo sapiens Bruton agammaglobulinemia...    52   9e-06
BC109080-1|AAI09081.1|  659|Homo sapiens Bruton agammaglobulinem...    52   9e-06
BC109079-1|AAI09080.1|  659|Homo sapiens Bruton agammaglobulinem...    52   9e-06
BC053559-1|AAH53559.1|  540|Homo sapiens growth factor receptor-...    52   9e-06
AL035422-3|CAB55876.1|  659|Homo sapiens Bruton agammaglobulinem...    52   9e-06
AL031683-1|CAD56150.1|  196|Homo sapiens phospholipase C, beta 1...    52   9e-06
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.        52   9e-06
AF182199-1|AAF59904.1| 1248|Homo sapiens intersectin 2 short iso...    52   9e-06
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof...    52   9e-06
AF001630-1|AAD00899.1|  464|Homo sapiens SH3P18-like WASP associ...    52   9e-06
AC110086-1|AAY24176.1|  172|Homo sapiens unknown protein.              52   9e-06
AC009228-1|AAX93122.1| 1329|Homo sapiens unknown protein.              52   9e-06
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.     52   9e-06
U47924-17|AAB51322.1|  556|Homo sapiens protein tyrosine phospha...    52   1e-05
Y14385-1|CAA74743.1| 1258|Homo sapiens inositol polyphosphate 5-...    52   2e-05
U15528-1|AAA82879.1|  556|Homo sapiens protein tyrosine phosphat...    52   2e-05
M15990-1|AAA35735.1|  543|Homo sapiens protein ( Human c-yes-1 m...    52   2e-05
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.                   52   2e-05
CR456441-1|CAG30327.1|  749|Homo sapiens dJ1042K10.2 protein.          52   2e-05
BC127850-1|AAI27851.1|  361|Homo sapiens Unknown (protein for IM...    52   2e-05
BC048960-1|AAH48960.1|  543|Homo sapiens v-yes-1 Yamaguchi sarco...    52   2e-05
BC008078-1|AAH08078.1|  749|Homo sapiens RUN and TBC1 domain con...    52   2e-05
AY308849-1|AAQ81879.1|  749|Homo sapiens merlin binding protein ...    52   2e-05
AL390754-3|CAI12462.1|   66|Homo sapiens Rho guanine nucleotide ...    52   2e-05
AL022238-3|CAA18266.1|  777|Homo sapiens protein ( Human DNA seq...    52   2e-05
AB196956-1|BAE02561.1|  749|Homo sapiens Rab-GTPase-activating-p...    52   2e-05
D43772-1|BAA07827.1|  532|Homo sapiens GRB-7 SH2 domain protein ...    51   2e-05
BT006686-1|AAP35332.1|  532|Homo sapiens growth factor receptor-...    51   2e-05
BC006535-1|AAH06535.1|  532|Homo sapiens growth factor receptor-...    51   2e-05
AL583849-1|CAH73120.1|  509|Homo sapiens Src homology 2 domain c...    51   2e-05
AL161448-1|CAH73192.1|  509|Homo sapiens Src homology 2 domain c...    51   2e-05
AL138752-4|CAI13876.1|  509|Homo sapiens Src homology 2 domain c...    51   2e-05
AK222870-1|BAD96590.1|  532|Homo sapiens growth factor receptor-...    51   2e-05
AK222849-1|BAD96569.1|  532|Homo sapiens growth factor receptor-...    51   2e-05
AF274875-1|AAG25938.1|  532|Homo sapiens growth factor receptor-...    51   2e-05
AB008789-1|BAA29059.1|  532|Homo sapiens grb7 protein protein.         51   2e-05
DQ090887-1|AAY99645.1| 1196|Homo sapiens AHI1 protein.                 51   3e-05
AL133544-3|CAI22523.1| 1168|Homo sapiens protein ( Human DNA seq...    51   3e-05
AL049552-2|CAI20387.1| 1168|Homo sapiens protein ( EB-RP (G13), ...    51   3e-05
AL023693-5|CAI20201.1| 1168|Homo sapiens protein ( Human DNA seq...    51   3e-05
AK092262-1|BAC03840.1| 1196|Homo sapiens protein ( Homo sapiens ...    51   3e-05
AJ606362-1|CAE54481.1| 1196|Homo sapiens AHI1 protein protein.         51   3e-05
AJ459824-1|CAD30871.1| 1196|Homo sapiens AHI1 protein protein.         51   3e-05
X83107-1|CAA58169.1|  675|Homo sapiens bmx protein.                    50   4e-05
X75342-1|CAA53091.1|  596|Homo sapiens Shb protein.                    50   4e-05
U20158-1|AAC50135.1|  533|Homo sapiens SLP-76 protein.                 50   4e-05
M79321-1|AAB50019.1|  491|Homo sapiens Lyn B protein protein.          50   4e-05
M16038-1|AAA59540.1|  512|Homo sapiens LYN protein.                    50   4e-05
BT007273-1|AAP35937.1|  533|Homo sapiens lymphocyte cytosolic pr...    50   4e-05
BC126458-1|AAI26459.1|  512|Homo sapiens LYN protein protein.          50   4e-05
BC126456-1|AAI26457.1|  512|Homo sapiens LYN protein protein.          50   4e-05
BC075002-1|AAH75002.1|  512|Homo sapiens v-yes-1 Yamaguchi sarco...    50   4e-05
BC075001-1|AAH75001.1|  512|Homo sapiens v-yes-1 Yamaguchi sarco...    50   4e-05
BC068551-1|AAH68551.1|  582|Homo sapiens LYN protein protein.          50   4e-05
BC059394-1|AAH59394.1|  582|Homo sapiens LYN protein protein.          50   4e-05
BC016652-1|AAH16652.1|  675|Homo sapiens BMX non-receptor tyrosi...    50   4e-05
BC016618-1|AAH16618.1|  533|Homo sapiens lymphocyte cytosolic pr...    50   4e-05
BC007586-1|AAH07586.1|  233|Homo sapiens SHF protein protein.          50   4e-05
AL731544-3|CAI14998.1|  431|Homo sapiens novel SH2 domain-contai...    50   4e-05
AL360254-1|CAB96175.1|  392|Homo sapiens SCK protein.                  50   4e-05
AB001451-1|BAA25798.1|  540|Homo sapiens Sck protein.                  50   4e-05
X95677-1|CAA64980.1|  299|Homo sapiens argBPIB protein.                50   5e-05
X95632-1|CAA64885.1|  475|Homo sapiens Arg protein tyrosine kina...    50   5e-05
U23435-1|AAA92289.1|  401|Homo sapiens Abl interactor 2 protein.       50   5e-05
L10717-1|AAA36748.1|  620|Homo sapiens tyrosine kinase protein.        50   5e-05
D13720-1|BAA02873.1|  620|Homo sapiens ITK protein.                    50   5e-05
BT009920-1|AAP88922.1|  475|Homo sapiens abl-interactor 2 protein.     50   5e-05
BC109078-1|AAI09079.1|  620|Homo sapiens IL2-inducible T-cell ki...    50   5e-05
BC109077-1|AAI09078.1|  620|Homo sapiens IL2-inducible T-cell ki...    50   5e-05
BC001439-1|AAH01439.1|  475|Homo sapiens abl interactor 2 protein.     50   5e-05
AF260261-1|AAF70308.1|  513|Homo sapiens Abl-interactor protein ...    50   5e-05
AC018891-1|AAY14675.1|  321|Homo sapiens unknown protein.              50   5e-05
X05027-1|CAA28691.1|  507|Homo sapiens protein ( Human T cell-sp...    50   7e-05
U53470-1|AAD00081.1| 1189|Homo sapiens signaling inositol polyph...    50   7e-05
U50041-1|AAC50454.1| 1179|Homo sapiens signaling inositol polyph...    50   7e-05
S65186-1|AAB28072.2|  620|Homo sapiens EMT protein.                    50   7e-05
DQ340865-1|ABC69037.1| 1076|Homo sapiens intersectin 1 short for...    50   7e-05
BC033907-1|AAH33907.1|  630|Homo sapiens SHC (Src homology 2 dom...    50   7e-05
BC017751-1|AAH17751.1|  330|Homo sapiens FCHSD2 protein protein.       50   7e-05
AY464565-1|AAR19363.1|  630|Homo sapiens rai-like protein RaLP p...    50   7e-05
AY358250-1|AAQ88617.1|  387|Homo sapiens LPAL6438 protein.             50   7e-05
AF045459-1|AAC08966.1|  697|Homo sapiens Etk/Bmx cytosolic tyros...    50   7e-05
AB018312-1|BAA34489.2|  746|Homo sapiens KIAA0769 protein protein.     50   7e-05
Z29630-1|CAA82737.1|  612|Homo sapiens protein-tyrosine kinase p...    49   9e-05
X73568-1|CAA51970.1|  630|Homo sapiens protein tyrosin kinase pr...    49   9e-05
U13433-1|AAC51347.1|  657|Homo sapiens Bruton's agammaglobulinem...    49   9e-05
M19722-1|AAA52451.1|  529|Homo sapiens FGR protein.                    49   9e-05
M14676-1|AAA36615.1|  537|Homo sapiens protein ( Human src-like ...    49   9e-05
M12724-1|AAA52762.1|  306|Homo sapiens FGR protein.                    49   9e-05
L28824-1|AAA36526.1|  635|Homo sapiens protein tyrosine kinase p...    49   9e-05
BC064382-1|AAH64382.1|  529|Homo sapiens Gardner-Rasheed feline ...    49   9e-05
BC011399-1|AAH11399.1|  612|Homo sapiens SYK protein protein.          49   9e-05
BC005381-1|AAH05381.1|  283|Homo sapiens Unknown (protein for IM...    49   9e-05
BC002962-1|AAH02962.1|  635|Homo sapiens spleen tyrosine kinase ...    49   9e-05
BC001645-1|AAH01645.1|  635|Homo sapiens spleen tyrosine kinase ...    49   9e-05
AL358075-1|CAI21701.1|  206|Homo sapiens phosphoinositide-3-kina...    49   9e-05
AL354862-3|CAI16875.1|  612|Homo sapiens spleen tyrosine kinase ...    49   9e-05
AL354862-2|CAI16876.1|  635|Homo sapiens spleen tyrosine kinase ...    49   9e-05
AL031729-3|CAB62998.1|  529|Homo sapiens Gardner-Rasheed feline ...    49   9e-05
AL031729-2|CAI19617.1|  313|Homo sapiens Gardner-Rasheed feline ...    49   9e-05
CR533523-1|CAG38554.1|  445|Homo sapiens PACSIN2 protein.              49   1e-04
CR456536-1|CAG30422.1|  486|Homo sapiens PACSIN2 protein.              49   1e-04
BC108893-1|AAI08894.1|  728|Homo sapiens SH3D19 protein protein.       49   1e-04
BC108892-1|AAI08893.1|  764|Homo sapiens SH3D19 protein protein.       49   1e-04
BC108891-1|AAI08892.1|  764|Homo sapiens SH3D19 protein protein.       49   1e-04
BC108890-1|AAI08891.1|  764|Homo sapiens SH3D19 protein protein.       49   1e-04
BC085613-1|AAH85613.1|  420|Homo sapiens SH3D19 protein protein.       49   1e-04
BC045742-1|AAH45742.1|  208|Homo sapiens SH3D19 protein protein.       49   1e-04
BC032468-1|AAH32468.1|  104|Homo sapiens DKFZp434D0215 protein p...    49   1e-04
BC008037-1|AAH08037.1|  486|Homo sapiens PACSIN2 protein protein.      49   1e-04
AL389984-1|CAB97538.1|  111|Homo sapiens PACSIN2 protein.              49   1e-04
AL133047-1|CAB61374.1|  408|Homo sapiens hypothetical protein pr...    49   1e-04
AL049758-1|CAI20948.1|  486|Homo sapiens protein kinase C and ca...    49   1e-04
AL022476-1|CAI20163.1|  486|Homo sapiens protein kinase C and ca...    49   1e-04
AF128536-1|AAD41781.1|  486|Homo sapiens cytoplasmic phosphoprot...    49   1e-04
Z97989-5|CAI22301.1|  534|Homo sapiens FYN oncogene related to S...    48   2e-04
Z97989-4|CAI22300.1|  537|Homo sapiens FYN oncogene related to S...    48   2e-04

>M34667-1|AAA36452.1| 1290|Homo sapiens protein ( Human phospholipase
            C-gamma mRNA, complete cds. ).
          Length = 1290

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 6    SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 65   ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 122  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 182  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 241  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 301  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 361  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 421  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 481  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 533  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 593  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 653  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 712  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 772  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRG 831

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 832  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 892  NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 951  LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211


>DQ297143-1|ABB84466.1| 1291|Homo sapiens phospholipase C, gamma 1
            protein.
          Length = 1291

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 6    SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 65   ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 122  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 182  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 241  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 301  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 361  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 421  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 481  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 533  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 593  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 653  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 712  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 772  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRG 831

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 832  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 892  NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 951  LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211


>AL022394-3|CAA18537.1| 1290|Homo sapiens phospholipase C, gamma 1
            protein.
          Length = 1290

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 6    SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 65   ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 122  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 182  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 241  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 301  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 361  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 421  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 481  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 533  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 593  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 653  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 712  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 772  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRG 831

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 832  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 892  NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 951  LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211


>AL022394-2|CAM28260.1| 1291|Homo sapiens phospholipase C, gamma 1
            protein.
          Length = 1291

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 6    SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 65   ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 122  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 182  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 241  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 301  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 361  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 421  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 481  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 533  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 593  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 653  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 712  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 772  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRG 831

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 832  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 892  NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 951  LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211


>AB210028-1|BAE06110.1| 1412|Homo sapiens PLCG1 variant protein
            protein.
          Length = 1412

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 128  SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 186

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 187  ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 243

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 244  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 303

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 304  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 362

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 363  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 422

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 423  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 482

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 483  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 542

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 543  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 602

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 603  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 654

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 655  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 714

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 715  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 774

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 775  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 833

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 834  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 893

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 894  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRG 953

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 954  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 1013

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 1014 NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 1072

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 1073 LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1132

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1133 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1192

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1193 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1250

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1251 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1310

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1311 AVPLKNNYSEDLELASLLIKIDI 1333


>BC018646-1|AAH18646.1| 1265|Homo sapiens PLCG2 protein protein.
          Length = 1265

 Score =  962 bits (2380), Expect = 0.0
 Identities = 517/1205 (42%), Positives = 728/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + LR+
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLRD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F S+Y LI HYR   LR  EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R   E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAM--Y 891
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P    Y
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKQQGY 883

Query: 892  SPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+YD+  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>BC014561-1|AAH14561.1| 1265|Homo sapiens PLCG2 protein protein.
          Length = 1265

 Score =  962 bits (2380), Expect = 0.0
 Identities = 517/1205 (42%), Positives = 728/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + LR+
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLRD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F S+Y LI HYR   LR  EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R   E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAM--Y 891
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P    Y
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKQQGY 883

Query: 892  SPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+YD+  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>BC011772-1|AAH11772.1| 1265|Homo sapiens PLCG2 protein protein.
          Length = 1265

 Score =  962 bits (2380), Expect = 0.0
 Identities = 517/1205 (42%), Positives = 728/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + LR+
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLRD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F S+Y LI HYR   LR  EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R   E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAM--Y 891
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P    Y
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKQQGY 883

Query: 892  SPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+YD+  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>BC007565-1|AAH07565.1| 1265|Homo sapiens PLCG2 protein protein.
          Length = 1265

 Score =  962 bits (2380), Expect = 0.0
 Identities = 517/1205 (42%), Positives = 728/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + LR+
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLRD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F S+Y LI HYR   LR  EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R   E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAM--Y 891
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P    Y
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKQQGY 883

Query: 892  SPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+YD+  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>AB208914-1|BAD92151.1| 1278|Homo sapiens
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            gamma 2 variant protein.
          Length = 1278

 Score =  957 bits (2368), Expect = 0.0
 Identities = 515/1205 (42%), Positives = 726/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 26   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 81

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 82   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 139

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 140  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 199

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + L +
Sbjct: 200  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHD 258

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 259  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 318

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 319  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 378

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 379  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 438

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 439  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 490

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 491  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 541

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 542  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 600

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F S+Y LI HYR   LR  EF + L +PVP PN HE K W+
Sbjct: 601  IRSTMEGGTLKYYLTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWY 660

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 661  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 719

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R   E D N++Y     Y+DP+   
Sbjct: 720  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEIN 779

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 780  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 839

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS- 892
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P     
Sbjct: 840  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKQQGD 896

Query: 893  -PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 897  PPVEFATDRVEELFEWFQSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 956

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 957  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1013

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1014 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1072

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+YD+  K  T  V+DNGL+P+W    
Sbjct: 1073 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYDNN-KFKTTVVNDNGLSPIWAPTQ 1130

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1131 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1190

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1191 ASLLV 1195


>X14034-1|CAA32194.1| 1252|Homo sapiens protein ( Human mRNA for
            phospholipase C. ).
          Length = 1252

 Score =  947 bits (2345), Expect = 0.0
 Identities = 512/1205 (42%), Positives = 724/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + L +
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F  +Y LI HYR   L   EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHLPCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R  +E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNTERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS- 892
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P     
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKEQGD 883

Query: 893  -PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDSKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+Y +  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYGNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>M37238-1|AAA60112.1| 1252|Homo sapiens PLC1 protein.
          Length = 1252

 Score =  947 bits (2345), Expect = 0.0
 Identities = 512/1205 (42%), Positives = 724/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + L +
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F  +Y LI HYR   L   EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHLPCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R  +E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNTERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS- 892
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P     
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKEQGD 883

Query: 893  -PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDSKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+Y +  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYGNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>AY364256-1|AAQ76815.1| 1252|Homo sapiens phospholipase C gamma 2
            protein.
          Length = 1252

 Score =  947 bits (2345), Expect = 0.0
 Identities = 512/1205 (42%), Positives = 724/1205 (60%), Gaps = 61/1205 (5%)

Query: 15   HEADQLISYIERGSTVLKF-FPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            +E  Q+   +E G+ +  F F +  PERR + V  ET QV WS+         EG LDI 
Sbjct: 13   YEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKT----ADKIEGFLDIM 68

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            ++KE+R GK+SKDFER   +  R +   CFTI YGT+F L   S  A + ++   W+ G+
Sbjct: 69   EIKEIRPGKNSKDFER--AKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAVNWLSGL 126

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEK-ITLKEVKAFLPKINCKISTSK-LRDV 191
              L  EA++AS P  IE WLRK+ YS++ +    I+L+E+K  LP IN K+S++K L+D 
Sbjct: 127  KILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDK 186

Query: 192  FQDVDTEKRGEIGFDDFAVLYQKLIFDEN-NVQDIFDKYSVYCSNGTT-------ITLRE 243
            F ++   K  E+ F+ F + Y+KL+F++  ++ D F K S     G T       + L +
Sbjct: 187  FVEIGAHK-DELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLHD 245

Query: 244  FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
            FQ FL  EQ ++   D  +  + +  ++ D  R+  EP+  + EF+  L+S++NSI+D +
Sbjct: 246  FQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEK 305

Query: 304  YDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
            YD V  QDM  PLSHYWISSSHNTYLTGDQ  SESS EAY+RCLR GCRCIELDCWDGPD
Sbjct: 306  YDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDCWDGPD 365

Query: 363  GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            G P IYHG T TTKI+F DV++ IK+HAF+TS +P+ILSIE++CS+ QQR MA AF++VF
Sbjct: 366  GKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKAFKEVF 425

Query: 423  GDLLLVHPMDKNETSLPSPHD-XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIK 481
            GDLLL  P + +   LPSP               P G  + +   +++E K        +
Sbjct: 426  GDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNMEDKKDEHK--------Q 477

Query: 482  NGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHF 541
             G L++ D +D++W  H   + + KL +++                      +P  ELHF
Sbjct: 478  QGELYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQD---------IPPTELHF 528

Query: 542  AECWFHGKLAGNRQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
             E WFH K+   R  AE LL+ +    G  DGTFLVRES TF  DY LSFWR G+V HCR
Sbjct: 529  GEKWFHKKVE-KRTSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCR 587

Query: 599  IKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWF 658
            I+   E G  K+YL D++ F  +Y LI HYR   L   EF + L +PVP PN HE K W+
Sbjct: 588  IRSTMEGGTLKYYLTDNLRFRRMYALIQHYRETHLPCAEFELRLTDPVPNPNPHESKPWY 647

Query: 659  HAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGT 718
            +   +R +AE++L +   DGAFL+R  E    S+AI+FR   ++KHCR+ ++GR + +GT
Sbjct: 648  YDSLSRGEAEDMLMRIPRDGAFLIRKREGSD-SYAITFRARGKVKHCRINRDGRHFVLGT 706

Query: 719  -VKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFT 776
               FESL+ELVSYYE H LY+K++L YP++ E + R  +E D N++Y     Y+DP+   
Sbjct: 707  SAYFESLVELVSYYEKHSLYRKMRLRYPVTPELLERYNTERDINSLYDVSRMYVDPSEIN 766

Query: 777  SKV---TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
              +   TVKALYDY+A++ DELSFC+ A+I NV K   GWW+GDYG +   +FP+NYV +
Sbjct: 767  PSMPQRTVKALYDYKAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVED 826

Query: 834  IEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS- 892
            I      ++   +  E   LGSL +G+LD+      +V    G   +  V +  P     
Sbjct: 827  ISTADFEELEKQI-IEDNPLGSLCRGILDL--NTYNVVKAPQGKNQKSFVFILEPKEQGD 883

Query: 893  -PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFN 951
             P + A    E   EW                     E+   IA E+SDL++YC+  +  
Sbjct: 884  PPVEFATDRVEELFEWFQSIREITWKIDSKENNMKYWEKNQSIAIELSDLVVYCKPTSKT 943

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
             + L    F   E+ SF ETKA+ ++ +Q+    +KY+   L+R+YPKGQR+DSSNY+P 
Sbjct: 944  KDNLENPDF--REIRSFVETKADSII-RQKPVDLLKYNQKGLTRVYPKGQRVDSSNYDPF 1000

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKV 1071
              W CGSQMVALN+QT DK MQ+N   F  NG  G++L+P+ M  E Y+P   +S + K+
Sbjct: 1001 RLWLCGSQMVALNFQTADKYMQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPES-QRKI 1059

Query: 1072 KPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDIC 1131
              +T+ ++V+GARHL K GR  A PFVEVEI GA+Y +  K  T  V+DNGL+P+W    
Sbjct: 1060 L-MTLTVKVLGARHLPKLGRSIACPFVEVEICGAEYGNN-KFKTTVVNDNGLSPIWAPTQ 1117

Query: 1132 E---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELEL 1188
            E   FE+ +P LA +RFVV +ED+F +PNF+  AT+P+  ++ G+RSVPL N +SE++EL
Sbjct: 1118 EKVTFEIYDPNLAFLRFVVYEEDMFSDPNFLAHATYPIKAVKSGFRSVPLKNGYSEDIEL 1177

Query: 1189 STLMV 1193
            ++L+V
Sbjct: 1178 ASLLV 1182


>DQ176850-1|ABA12209.1| 1416|Homo sapiens phospholipase C-eta2
           protein.
          Length = 1416

 Score =  248 bits (607), Expect = 9e-65
 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  ++EV  G+ S+ F+R+P+ +   + + CF+IY+G+  +      V+
Sbjct: 82  PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 137

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
            + +    WV G+ YL+A    E   A      ++WL++ F   + N    +++ EV   
Sbjct: 138 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 197

Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           L K+N  +   +++ +F++ DT+  +G +GF++F   Y+ +    +  +D++     Y +
Sbjct: 198 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 253

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294
           +   +     Q FL+ EQ   +    +++ Q I +       +  +    +  F     S
Sbjct: 254 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 311

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
               I++ ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E
Sbjct: 312 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 371

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M
Sbjct: 372 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 431

Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           A    D+ GD L L     ++ T+LPSP
Sbjct: 432 AQYLTDILGDKLDLSSVSSEDATTLPSP 459



 Score =  204 bits (498), Expect = 1e-51
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 615  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 670

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 671  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 730

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 731  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 789

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 790  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 847

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 848  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 881


>AB007919-1|BAA32295.3| 1182|Homo sapiens KIAA0450 protein protein.
          Length = 1182

 Score =  248 bits (607), Expect = 9e-65
 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  ++EV  G+ S+ F+R+P+ +   + + CF+IY+G+  +      V+
Sbjct: 108 PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 163

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
            + +    WV G+ YL+A    E   A      ++WL++ F   + N    +++ EV   
Sbjct: 164 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 223

Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           L K+N  +   +++ +F++ DT+  +G +GF++F   Y+ +    +  +D++     Y +
Sbjct: 224 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 279

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294
           +   +     Q FL+ EQ   +    +++ Q I +       +  +    +  F     S
Sbjct: 280 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 337

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
               I++ ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E
Sbjct: 338 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 397

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M
Sbjct: 398 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 457

Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           A    D+ GD L L     ++ T+LPSP
Sbjct: 458 AQYLTDILGDKLDLSSVSSEDATTLPSP 485



 Score =  204 bits (498), Expect = 1e-51
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 641  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 696

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 697  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 756

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 757  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 815

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 816  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 873

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 874  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 907


>AK122589-1|BAC56930.1| 1129|Homo sapiens FLJ00414 protein protein.
          Length = 1129

 Score =  245 bits (599), Expect = 9e-64
 Identities = 130/380 (34%), Positives = 221/380 (58%), Gaps = 17/380 (4%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEA 128
           A+ I  ++EV  G+ S+ F+R+P+ +   + + CF+IY+G+  +      V+ + +    
Sbjct: 8   AVSIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVSTSSEVART 63

Query: 129 WVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKI 183
           WV G+ YL+A    E   A      ++WL++ F   + N    +++ EV   L K+N  +
Sbjct: 64  WVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNL 123

Query: 184 STSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLR 242
              +++ +F++ DT+  +G +GF++F   Y+ +    +  +D++     Y ++   +   
Sbjct: 124 PRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSNHKDHLDAA 179

Query: 243 EFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDS 302
             Q FL+ EQ   +    +++ Q I +       +  +    +  F     S    I++ 
Sbjct: 180 SLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNP 237

Query: 303 QYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
           ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E+DCWDGPD
Sbjct: 238 EHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPD 297

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
           G P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++MA    D+ 
Sbjct: 298 GEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDIL 357

Query: 423 GDLL-LVHPMDKNETSLPSP 441
           GD L L     ++ T+LPSP
Sbjct: 358 GDKLDLSSVSSEDATTLPSP 377



 Score =  204 bits (498), Expect = 1e-51
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 533  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 588

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 589  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 648

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 649  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 707

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 708  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 765

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 766  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 799


>BC113950-1|AAI13951.1| 1655|Homo sapiens phospholipase C, eta 1
           protein.
          Length = 1655

 Score =  244 bits (597), Expect = 2e-63
 Identities = 132/389 (33%), Positives = 217/389 (55%), Gaps = 19/389 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  + +V  G+ S+ F R  E     + S CFTIY+G    +     + 
Sbjct: 37  PSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGN--FDPSCCFTIYHGNH--MESLDLIT 92

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
              +E   W+ G+ YL+A    E   A      ++W+++ F   + N    + ++E+   
Sbjct: 93  SNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQL 152

Query: 176 LPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           + K+N  +   K+R +FQ+ DT E +G + F++F V Y+ +       +D++     Y  
Sbjct: 153 MHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLR----RDLYLLLLSYSD 208

Query: 235 NGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293
               +T+ E   FL+ EQ  +N+  D       I+ +    +  + +    +  F   + 
Sbjct: 209 KKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTNFMR 265

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S    I++  + +V QDM +PL +Y+I+SSHNTYLTGDQ  S+S ++ Y R L+ GCRC+
Sbjct: 266 SPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCV 325

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ QQR+
Sbjct: 326 EVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRK 385

Query: 414 MASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           +A   + +FGD L +  +D  E   LPSP
Sbjct: 386 IAQYLKGIFGDKLDLSSVDTGECKQLPSP 414



 Score =  196 bits (479), Expect = 3e-49
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 572  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 628

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 629  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 687

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 688  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 746

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 747  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 804

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 805  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 837


>AY691171-1|AAW22608.1| 1693|Homo sapiens phospholipase C-eta1b
           protein.
          Length = 1693

 Score =  244 bits (597), Expect = 2e-63
 Identities = 132/389 (33%), Positives = 217/389 (55%), Gaps = 19/389 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  + +V  G+ S+ F R  E     + S CFTIY+G    +     + 
Sbjct: 55  PSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGN--FDPSCCFTIYHGNH--MESLDLIT 110

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
              +E   W+ G+ YL+A    E   A      ++W+++ F   + N    + ++E+   
Sbjct: 111 SNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQL 170

Query: 176 LPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           + K+N  +   K+R +FQ+ DT E +G + F++F V Y+ +       +D++     Y  
Sbjct: 171 MHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLR----RDLYLLLLSYSD 226

Query: 235 NGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293
               +T+ E   FL+ EQ  +N+  D       I+ +    +  + +    +  F   + 
Sbjct: 227 KKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTNFMR 283

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S    I++  + +V QDM +PL +Y+I+SSHNTYLTGDQ  S+S ++ Y R L+ GCRC+
Sbjct: 284 SPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCV 343

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ QQR+
Sbjct: 344 EVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRK 403

Query: 414 MASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           +A   + +FGD L +  +D  E   LPSP
Sbjct: 404 IAQYLKGIFGDKLDLSSVDTGECKQLPSP 432



 Score =  196 bits (479), Expect = 3e-49
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 590  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 646

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 647  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 705

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 706  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 764

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 765  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 822

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 823  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 855


>AY691170-1|AAW22607.1| 1002|Homo sapiens phospholipase C-eta1a
           protein.
          Length = 1002

 Score =  244 bits (597), Expect = 2e-63
 Identities = 132/389 (33%), Positives = 217/389 (55%), Gaps = 19/389 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  + +V  G+ S+ F R  E     + S CFTIY+G    +     + 
Sbjct: 55  PSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGN--FDPSCCFTIYHGNH--MESLDLIT 110

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
              +E   W+ G+ YL+A    E   A      ++W+++ F   + N    + ++E+   
Sbjct: 111 SNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQL 170

Query: 176 LPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           + K+N  +   K+R +FQ+ DT E +G + F++F V Y+ +       +D++     Y  
Sbjct: 171 MHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLR----RDLYLLLLSYSD 226

Query: 235 NGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293
               +T+ E   FL+ EQ  +N+  D       I+ +    +  + +    +  F   + 
Sbjct: 227 KKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTNFMR 283

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S    I++  + +V QDM +PL +Y+I+SSHNTYLTGDQ  S+S ++ Y R L+ GCRC+
Sbjct: 284 SPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCV 343

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ QQR+
Sbjct: 344 EVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRK 403

Query: 414 MASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           +A   + +FGD L +  +D  E   LPSP
Sbjct: 404 IAQYLKGIFGDKLDLSSVDTGECKQLPSP 432



 Score =  196 bits (479), Expect = 3e-49
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 590  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 646

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 647  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 705

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 706  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 764

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 765  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 822

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 823  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 855


>BC006355-1|AAH06355.1|  762|Homo sapiens phospholipase C, delta 4
           protein.
          Length = 762

 Score =  237 bits (579), Expect = 2e-61
 Identities = 133/378 (35%), Positives = 213/378 (56%), Gaps = 15/378 (3%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECE 127
           +  I DV+ +R G  S+      EE   L   + FTI ++G    L     +A + +E +
Sbjct: 60  SFSISDVETIRNGHDSELLRSLAEE---LPLEQGFTIVFHGRRSNL---DLMANSVEEAQ 113

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFY-SIENSHEKITLKEVKAFLPKINCKISTS 186
            W++G+  L+    S  +  ++++WL   F    +N   K++ +EV+  L  +N ++   
Sbjct: 114 IWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQE 173

Query: 187 KLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQN 246
               +FQ  DT + G +  ++F   Y K +     VQ++F+ +S   ++G  +TL EF +
Sbjct: 174 YAFSLFQAADTSQSGTLEGEEFVQFY-KALTKRAEVQELFESFS---ADGQKLTLLEFLD 229

Query: 247 FLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDK 306
           FL++EQ +     E+ A + I  Y       +     ++  F+  L SK   I++     
Sbjct: 230 FLQEEQKERDCTSEL-ALELIDRYEPSDSGKLRH-VLSMDGFLSYLCSKDGDIFNPACLP 287

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           + QDMT+PL+HY+I SSHNTYL GDQ   +SS+E Y+R L+ GCRC+E+D WDGP G P 
Sbjct: 288 IYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPV 347

Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426
           +YHGHTLT++I F DV+ T+ ++AF TS+YP+ILS+E +CS  QQ+ MA    ++ G+ L
Sbjct: 348 VYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQL 407

Query: 427 LVHPMD-KNETSLPSPHD 443
           L   +D    T LPSP +
Sbjct: 408 LSTTLDGVLPTQLPSPEE 425



 Score =  195 bits (476), Expect = 7e-49
 Identities = 109/266 (40%), Positives = 158/266 (59%), Gaps = 11/266 (4%)

Query: 938  ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997
            +S L+IY +SV+F       + + + E+SSF ETKA+RL+ +  N F V+++T QLSR+Y
Sbjct: 493  LSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEF-VQHNTWQLSRVY 551

Query: 998  PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055
            P G R DSSNYNP   WN G QMVA+N QT    M +  G F+QNGGCG++LKP F+   
Sbjct: 552  PSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDI 611

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGT-ASPFVEVEIIGADYDSGV 1111
            +  ++P  +K I    K  T++++VI  + L    KT  G+   P V+V+I G   D+  
Sbjct: 612  QSSFHP--EKPI-SPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDT-A 667

Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
            +  T  V +NG NP W     F V  PELA++RFVV D D     +FIGQ T P  C+++
Sbjct: 668  RQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQ 727

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GYR + L +     L  +++ V++ I
Sbjct: 728  GYRHIHLLSKDGISLRPASIFVYICI 753


>AK223203-1|BAD96923.1|  762|Homo sapiens phospholipase C, delta 4
           variant protein.
          Length = 762

 Score =  236 bits (578), Expect = 3e-61
 Identities = 133/378 (35%), Positives = 213/378 (56%), Gaps = 15/378 (3%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECE 127
           +  I DV+ +R G  S+      EE   L   + FTI ++G    L     +A + +E +
Sbjct: 60  SFSISDVETIRNGHDSELLRSLAEE---LPLEQGFTIVFHGHRSNL---DLMANSVEEAQ 113

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFY-SIENSHEKITLKEVKAFLPKINCKISTS 186
            W++G+  L+    S  +  ++++WL   F    +N   K++ +EV+  L  +N ++   
Sbjct: 114 IWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQE 173

Query: 187 KLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQN 246
               +FQ  DT + G +  ++F   Y K +     VQ++F+ +S   ++G  +TL EF +
Sbjct: 174 YAFSLFQAADTSQSGTLEGEEFVQFY-KALTKRAEVQELFESFS---ADGQKLTLLEFLD 229

Query: 247 FLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDK 306
           FL++EQ +     E+ A + I  Y       +     ++  F+  L SK   I++     
Sbjct: 230 FLQEEQKERDCTSEL-ALELIDRYEPSDSGKLRH-VLSMDGFLSYLCSKDGDIFNPACLP 287

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           + QDMT+PL+HY+I SSHNTYL GDQ   +SS+E Y+R L+ GCRC+E+D WDGP G P 
Sbjct: 288 IYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPV 347

Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426
           +YHGHTLT++I F DV+ T+ ++AF TS+YP+ILS+E +CS  QQ+ MA    ++ G+ L
Sbjct: 348 VYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQL 407

Query: 427 LVHPMD-KNETSLPSPHD 443
           L   +D    T LPSP +
Sbjct: 408 LSTTLDGVLPTQLPSPEE 425



 Score =  195 bits (476), Expect = 7e-49
 Identities = 109/266 (40%), Positives = 158/266 (59%), Gaps = 11/266 (4%)

Query: 938  ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997
            +S L+IY +SV+F       + + + E+SSF ETKA+RL+ +  N F V+++T QLSR+Y
Sbjct: 493  LSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEF-VQHNTWQLSRVY 551

Query: 998  PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055
            P G R DSSNYNP   WN G QMVA+N QT    M +  G F+QNGGCG++LKP F+   
Sbjct: 552  PSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDI 611

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGT-ASPFVEVEIIGADYDSGV 1111
            +  ++P  +K I    K  T++++VI  + L    KT  G+   P V+V+I G   D+  
Sbjct: 612  QSSFHP--EKPI-SPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDT-A 667

Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
            +  T  V +NG NP W     F V  PELA++RFVV D D     +FIGQ T P  C+++
Sbjct: 668  RQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQ 727

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GYR + L +     L  +++ V++ I
Sbjct: 728  GYRHIHLLSKDGISLRPASIFVYICI 753


>AB209862-1|BAD93099.1|  776|Homo sapiens Phospholipase C, delta 1
           variant protein.
          Length = 776

 Score =  232 bits (568), Expect = 5e-60
 Identities = 133/426 (31%), Positives = 218/426 (51%), Gaps = 15/426 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + +GS +LK        R      +E  + +W       R        I D++E
Sbjct: 36  DEDLQALLKGSQLLKV-KSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQE 94

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  ++  E++  +   +   +CF+I +  +        +A +  + + WV G+  +I
Sbjct: 95  VRMGHRTEGLEKFARD---VPEDRCFSIVFKDQ--RNTLDLIAPSPADAQHWVLGLHKII 149

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
             + S     +++ W+       + N   K++ KE++ FL ++N ++  S  R +F++ D
Sbjct: 150 HHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECD 209

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
             +   +  ++    Y+ L        +I   ++    +G T+++ +   FL+ +Q +  
Sbjct: 210 HSQTDSLEDEEIEAFYKML----TQRVEIDRTFAEAAGSGETLSVNQLVTFLQHQQREEA 265

Query: 257 GDDEVQASQFIRDYLRDPQRDIY-EPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPL 315
               +  S  I  Y  +P      +   T   F+  L S   S +   + +V QDM +PL
Sbjct: 266 AGPALALS-LIERY--EPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPL 322

Query: 316 SHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTT 375
           SHY +SSSHNTYL  DQ +  SS EAY+R L  GCRC+ELDCWDGP+  P IYHG+T T+
Sbjct: 323 SHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTS 382

Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE 435
           KI F DVLR I+++AF  S YP+ILS+E++C+L QQR MA     + G +LL  P+D   
Sbjct: 383 KILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVT 442

Query: 436 TSLPSP 441
            SLPSP
Sbjct: 443 NSLPSP 448



 Score =  198 bits (484), Expect = 7e-50
 Identities = 113/272 (41%), Positives = 162/272 (59%), Gaps = 11/272 (4%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            R+A+E+SD++IYC+SV F         G  + EM+SF E +A RL+ +  N F V+++  
Sbjct: 507  RLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGF-VRHNVG 565

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             LSRIYP G R DSSNY+PV  WN G Q+VALN+QTP   M V  G+F+ NG CG++LKP
Sbjct: 566  HLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKP 625

Query: 1052 QFMFEEG--YNPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGA 1105
             F+ +    +NP  +   +G       + +RVI  + L K  +   S   P V VEI G 
Sbjct: 626  AFLRDPNGTFNP--RALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGV 683

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   +  T  +++NG NP W+    FEV  P+LALIRF+V+D D   + +FIGQ+T P
Sbjct: 684  SRDVASR-QTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIP 742

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  L++GYR V L +   ++   +TL V +S+
Sbjct: 743  LNSLKQGYRHVHLMSKNGDQHPSATLFVKISL 774


>BC050382-1|AAH50382.2|  756|Homo sapiens phospholipase C, delta 1
           protein.
          Length = 756

 Score =  231 bits (566), Expect = 9e-60
 Identities = 133/426 (31%), Positives = 218/426 (51%), Gaps = 15/426 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + +GS +LK        R      +E  + +W       R        I D++E
Sbjct: 16  DEDLQALLKGSQLLKV-KSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQE 74

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  ++  E++  +   +   +CF+I +  +        +A +  + + WV G+  +I
Sbjct: 75  VRMGHRTEGLEKFARD---VPEDRCFSIVFKDQ--RNTLDLIAPSPADAQHWVLGLHKII 129

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
             + S     +++ W+       + N   K++ KE++ FL ++N ++  S  R +F++ D
Sbjct: 130 HHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECD 189

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
             +   +  ++    Y+ L        +I   ++    +G T+++ +   FL+ +Q +  
Sbjct: 190 HSQTDSLEDEEIEAFYKML----TQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEA 245

Query: 257 GDDEVQASQFIRDYLRDPQRDIY-EPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPL 315
               +  S  I  Y  +P      +   T   F+  L S   S +   + +V QDM +PL
Sbjct: 246 AGPALALS-LIERY--EPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPL 302

Query: 316 SHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTT 375
           SHY +SSSHNTYL  DQ +  SS EAY+R L  GCRC+ELDCWDGP+  P IYHG+T T+
Sbjct: 303 SHYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTS 362

Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE 435
           KI F DVLR I+++AF  S YP+ILS+E++C+L QQR MA     + G +LL  P+D   
Sbjct: 363 KILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVT 422

Query: 436 TSLPSP 441
            SLPSP
Sbjct: 423 NSLPSP 428



 Score =  198 bits (484), Expect = 7e-50
 Identities = 113/272 (41%), Positives = 162/272 (59%), Gaps = 11/272 (4%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            R+A+E+SD++IYC+SV F         G  + EM+SF E +A RL+ +  N F V+++  
Sbjct: 487  RLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGF-VRHNVG 545

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             LSRIYP G R DSSNY+PV  WN G Q+VALN+QTP   M V  G+F+ NG CG++LKP
Sbjct: 546  HLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQGRFQDNGACGYVLKP 605

Query: 1052 QFMFEEG--YNPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGA 1105
             F+ +    +NP  +   +G       + +RVI  + L K  +   S   P V VEI G 
Sbjct: 606  AFLRDPNGTFNP--RALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGV 663

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   +  T  +++NG NP W+    FEV  P+LALIRF+V+D D   + +FIGQ+T P
Sbjct: 664  SRDVASR-QTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIP 722

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  L++GYR V L +   ++   +TL V +S+
Sbjct: 723  LNSLKQGYRHVHLMSKNGDQHPSATLFVKISL 754


>BC072384-1|AAH72384.1|  789|Homo sapiens phospholipase C, delta 3
           protein.
          Length = 789

 Score =  231 bits (565), Expect = 1e-59
 Identities = 143/460 (31%), Positives = 230/460 (50%), Gaps = 18/460 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + RGS + K   R   + R   ++ +   V W +   P R   +    ++ ++ 
Sbjct: 59  DEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSV-WFQRRIP-RAPSQHIFFVQHIEA 116

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  S+   R+         ++C TI +  + + +     A T +E + WV+G+  L 
Sbjct: 117 VREGHQSEGLRRFGGA---FAPARCLTIAF--KGRRKNLDLAAPTAEEAQRWVRGLTKLR 171

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
           A   + S   +++ W+    +  + N   K++ KE+K+ L  +N  ++      +F++ D
Sbjct: 172 ARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECD 231

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
                 +   +     ++L+     +++IF +YS        ++  E   FL D+  +  
Sbjct: 232 HSNNDRLEGAEIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE-- 285

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
           G    +A Q I+ Y  +     +E   TL  F+  L S + +  D+ +  V QDM +PL+
Sbjct: 286 GATLARAQQLIQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLA 344

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY+ISSSHNTYLT  Q    SS EAYVR    GCRC+ELDCW+GP G P IYHGHTLT+K
Sbjct: 345 HYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSK 404

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NE 435
           I F DV++ +++HAF  S YP+ILS+E++C L QQ  MA     + GD+L+   +D  N 
Sbjct: 405 ILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNP 464

Query: 436 TSLPSPHDXXXXXXXXXXXXPEGAEESSFAV--RQEEGKD 473
             LPSP              P    E   A+  R+EE +D
Sbjct: 465 EELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEED 504



 Score =  168 bits (408), Expect = 1e-40
 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I+ E+S L +YC +                ++SS  E KA++L+ +  N+F V+++  Q
Sbjct: 523  QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 581

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L+R+YP G R++S+NY+P   WN G Q+VALN+QTP   M +N G+F  NG CG++LKP 
Sbjct: 582  LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 641

Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107
             + +    P      E    P  T+ ++V+ A+ L K           P V +EI G   
Sbjct: 642  CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 697

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   +  T  V +NG NP W    +F++  PELAL+RFVV+D D     +F+GQ T PL 
Sbjct: 698  DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 756

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L++GYR + L +     L  +TL + + I
Sbjct: 757  SLKQGYRHIHLLSKDGASLSPATLFIQIRI 786


>AK074240-1|BAB85029.1|  789|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23660 fis, clone HEP00931. ).
          Length = 789

 Score =  231 bits (565), Expect = 1e-59
 Identities = 143/460 (31%), Positives = 230/460 (50%), Gaps = 18/460 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + RGS + K   R   + R   ++ +   V W +   P R   +    ++ ++ 
Sbjct: 59  DEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSV-WFQRRIP-RAPSQHIFFVQHIEA 116

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  S+   R+         ++C TI +  + + +     A T +E + WV+G+  L 
Sbjct: 117 VREGHQSEGLRRFGGA---FAPARCLTIAF--KGRRKNLDLAAPTAEEAQRWVRGLTKLR 171

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
           A   + S   +++ W+    +  + N   K++ KE+K+ L  +N  ++      +F++ D
Sbjct: 172 ARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECD 231

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
                 +   +     ++L+     +++IF +YS        ++  E   FL D+  +  
Sbjct: 232 HSNNDRLEGAEIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE-- 285

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
           G    +A Q I+ Y  +     +E   TL  F+  L S + +  D+ +  V QDM +PL+
Sbjct: 286 GATLARAQQLIQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLA 344

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY+ISSSHNTYLT  Q    SS EAYVR    GCRC+ELDCW+GP G P IYHGHTLT+K
Sbjct: 345 HYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSK 404

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NE 435
           I F DV++ +++HAF  S YP+ILS+E++C L QQ  MA     + GD+L+   +D  N 
Sbjct: 405 ILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNP 464

Query: 436 TSLPSPHDXXXXXXXXXXXXPEGAEESSFAV--RQEEGKD 473
             LPSP              P    E   A+  R+EE +D
Sbjct: 465 EELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEED 504



 Score =  168 bits (408), Expect = 1e-40
 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I+ E+S L +YC +                ++SS  E KA++L+ +  N+F V+++  Q
Sbjct: 523  QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 581

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L+R+YP G R++S+NY+P   WN G Q+VALN+QTP   M +N G+F  NG CG++LKP 
Sbjct: 582  LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 641

Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107
             + +    P      E    P  T+ ++V+ A+ L K           P V +EI G   
Sbjct: 642  CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 697

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   +  T  V +NG NP W    +F++  PELAL+RFVV+D D     +F+GQ T PL 
Sbjct: 698  DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 756

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L++GYR + L +     L  +TL + + I
Sbjct: 757  SLKQGYRHIHLLSKDGASLSPATLFIQIRI 786


>AB075844-1|BAB85550.1|  757|Homo sapiens KIAA1964 protein protein.
          Length = 757

 Score =  231 bits (565), Expect = 1e-59
 Identities = 143/460 (31%), Positives = 230/460 (50%), Gaps = 18/460 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + RGS + K   R   + R   ++ +   V W +   P R   +    ++ ++ 
Sbjct: 27  DEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSV-WFQRRIP-RAPSQHIFFVQHIEA 84

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  S+   R+         ++C TI +  + + +     A T +E + WV+G+  L 
Sbjct: 85  VREGHQSEGLRRFGGA---FAPARCLTIAF--KGRRKNLDLAAPTAEEAQRWVRGLTKLR 139

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
           A   + S   +++ W+    +  + N   K++ KE+K+ L  +N  ++      +F++ D
Sbjct: 140 ARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECD 199

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
                 +   +     ++L+     +++IF +YS        ++  E   FL D+  +  
Sbjct: 200 HSNNDRLEGAEIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE-- 253

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
           G    +A Q I+ Y  +     +E   TL  F+  L S + +  D+ +  V QDM +PL+
Sbjct: 254 GATLARAQQLIQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLA 312

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY+ISSSHNTYLT  Q    SS EAYVR    GCRC+ELDCW+GP G P IYHGHTLT+K
Sbjct: 313 HYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSK 372

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NE 435
           I F DV++ +++HAF  S YP+ILS+E++C L QQ  MA     + GD+L+   +D  N 
Sbjct: 373 ILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNP 432

Query: 436 TSLPSPHDXXXXXXXXXXXXPEGAEESSFAV--RQEEGKD 473
             LPSP              P    E   A+  R+EE +D
Sbjct: 433 EELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEED 472



 Score =  168 bits (408), Expect = 1e-40
 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I+ E+S L +YC +                ++SS  E KA++L+ +  N+F V+++  Q
Sbjct: 491  QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 549

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L+R+YP G R++S+NY+P   WN G Q+VALN+QTP   M +N G+F  NG CG++LKP 
Sbjct: 550  LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 609

Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107
             + +    P      E    P  T+ ++V+ A+ L K           P V +EI G   
Sbjct: 610  CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 665

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   +  T  V +NG NP W    +F++  PELAL+RFVV+D D     +F+GQ T PL 
Sbjct: 666  DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 724

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L++GYR + L +     L  +TL + + I
Sbjct: 725  SLKQGYRHIHLLSKDGASLSPATLFIQIRI 754


>U09117-1|AAA73567.1|  756|Homo sapiens phospholipase c delta 1
           protein.
          Length = 756

 Score =  231 bits (564), Expect = 2e-59
 Identities = 132/425 (31%), Positives = 216/425 (50%), Gaps = 13/425 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + +GS +LK        R      +E  + +W       R        I D++E
Sbjct: 16  DEDLQALLKGSQLLKV-KSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQE 74

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  ++  E++  +   +   +CF+I +  +        +A +  + + WV G+  +I
Sbjct: 75  VRMGHRTEGLEKFARD---VPEDRCFSIVFKDQ--RNTLDLIAPSPADAQHWVLGLHKII 129

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
             + S     +++ W+       + N   K++ KE++ FL ++N ++  S  R +F++ D
Sbjct: 130 HHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECD 189

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
             +   +  ++    Y+ L        +I   ++     G T+++ +   FL+ +Q +  
Sbjct: 190 HSQTDSLEDEEIEAFYKML----TQRVEIDRTFAEAAGPGETLSVDQLVTFLQHQQREEA 245

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
               +  S  I  Y    +    +   T   F+  L S   S +   + +V QDM +PLS
Sbjct: 246 AGPALALS-LIERY-EPSETTKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLS 303

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY +SSSHNTYL  DQ +  SS EAY+R L  GCRC+ELDCWDGP+  P IYHG+T T+K
Sbjct: 304 HYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSK 363

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET 436
           I F DVLR I+++AF  S YP+ILS+E++C+L QQR MA     + G +LL  P+D    
Sbjct: 364 ILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTN 423

Query: 437 SLPSP 441
           SLPSP
Sbjct: 424 SLPSP 428



 Score =  196 bits (477), Expect = 5e-49
 Identities = 112/272 (41%), Positives = 161/272 (59%), Gaps = 11/272 (4%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            R+A+E+SD++IYC+SV F         G  + EM+SF E +A RL+ +  N F V+++  
Sbjct: 487  RLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGF-VRHNVG 545

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             LSRIYP G R DSSNY+PV  WN G Q+VALN+QTP   M V   +F+ NG CG++LKP
Sbjct: 546  HLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQDRFQDNGACGYVLKP 605

Query: 1052 QFMFEEG--YNPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGA 1105
             F+ +    +NP  +   +G       + +RVI  + L K  +   S   P V VEI G 
Sbjct: 606  AFLRDPNGTFNP--RALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGV 663

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   +  T  +++NG NP W+    FEV  P+LALIRF+V+D D   + +FIGQ+T P
Sbjct: 664  SRDVASR-QTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIP 722

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  L++GYR V L +   ++   +TL V +S+
Sbjct: 723  LNSLKQGYRHVHLMSKNGDQHPSATLFVKISL 754


>BC128207-1|AAI28208.1| 1032|Homo sapiens PLCH2 protein protein.
          Length = 1032

 Score =  230 bits (562), Expect = 3e-59
 Identities = 121/347 (34%), Positives = 201/347 (57%), Gaps = 15/347 (4%)

Query: 102 CFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEF 157
           CF+IY+G+  +      V+ + +    WV G+ YL+A    E   A      ++WL++ F
Sbjct: 6   CFSIYHGSHRE--SLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTF 63

Query: 158 YSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKL 215
              + N    +++ EV   L K+N  +   +++ +F++ DT+  +G +GF++F   Y+ +
Sbjct: 64  DEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM 123

Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275
               +  +D++     Y ++   +     Q FL+ EQ   +    +++ Q I +      
Sbjct: 124 ----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCP 177

Query: 276 RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSS 335
            +  +    +  F     S    I++ ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S
Sbjct: 178 ENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMS 237

Query: 336 ESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           +S ++ Y   L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +E
Sbjct: 238 QSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNE 297

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           YP+ILSIE++CS+ QQ++MA    D+ GD L L     ++ T+LPSP
Sbjct: 298 YPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSP 344



 Score =  204 bits (498), Expect = 1e-51
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 500  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 555

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 556  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 615

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 616  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 674

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 675  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 732

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 733  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 766


>D42108-1|BAA07688.1|  997|Homo sapiens Phospholipase C protein.
          Length = 997

 Score =  216 bits (527), Expect = 5e-55
 Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 9/271 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            R+ +E+SDL+  C+SV +    L +K   Y EM SF ET+A R+ ++    F V Y+   
Sbjct: 482  RLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDF-VNYNKKF 540

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYP   RIDSSN NP  FWNCG Q+VA+N+QTP   M ++ G F QNGGCG++L+P 
Sbjct: 541  LSRIYPSAMRIDSSNLNPQDFWNCGCQIVAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS 600

Query: 1053 FMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTA-----SPFVEVEIIGAD 1106
             M +E  Y   + K I   V P+ + +++I  ++  K     A      P+V +EI G  
Sbjct: 601  IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP 660

Query: 1107 YDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPL 1166
             D   +  TKTV  N  NP++++  EF+V  PELA+IRFVV D+D  G+  FIGQ T P 
Sbjct: 661  ADCSEQR-TKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGD-EFIGQYTIPF 718

Query: 1167 LCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             CL+ GYR VPL +   + +E  TL VH++I
Sbjct: 719  ECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 749



 Score =  186 bits (454), Expect = 3e-46
 Identities = 125/442 (28%), Positives = 212/442 (47%), Gaps = 24/442 (5%)

Query: 11  DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGA- 69
           ++ I  A+  IS+++ G  + K  P  R   R   +  +   + W     P ++  E A 
Sbjct: 4   EKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWE----PSKKDLEKAK 59

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           LDI  +KE+R GK+++ F       +  E    F+I +G  ++      VA +      W
Sbjct: 60  LDISAIKEIRLGKNTETFTNNGLADQICEDC-AFSILHGENYE--SLDLVANSADVANIW 116

Query: 130 VKGVLYLIAEA------VSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPK-INCK 182
           V G+ YL++ +      +  +       WL+  F + +     I L++    L K +N  
Sbjct: 117 VSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPT 176

Query: 183 ISTSKLRDVFQDVDTEKRG---EIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTI 239
           +  +K+R  F+++   K      +  ++F   + +L        +++        N   +
Sbjct: 177 LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELC----TRPEVYFLLVQISKNKEYL 232

Query: 240 TLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSI 299
              +   FL  EQ      +++      R  L +  R   + +  +  F + L S +  I
Sbjct: 233 DANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQ--KGFLAIDGFTQYLLSSECDI 290

Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359
           +D +  KV QDMT+PLSHY+I++SHNTYL  DQF   + +  Y+R L+ GCR +ELD  D
Sbjct: 291 FDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSD 350

Query: 360 GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQ 419
           G D  P + + + +TT + F  V+  I + AF+ SEYPLIL + ++CSLPQQ+ MA   +
Sbjct: 351 GSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMK 410

Query: 420 DVFGDLLLVHPMDKNETSLPSP 441
            VFG+ L       +E+ LPSP
Sbjct: 411 KVFGNKLYTEAPLPSESYLPSP 432


>BC043358-1|AAH43358.1| 1238|Homo sapiens PLCH2 protein protein.
          Length = 1238

 Score =  216 bits (527), Expect = 5e-55
 Identities = 107/294 (36%), Positives = 177/294 (60%), Gaps = 9/294 (3%)

Query: 151 RWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDF 208
           +WL++ F   + N    +++ EV   L K+N  +   +++ +F++ DT+  +G +GF++F
Sbjct: 30  KWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEF 89

Query: 209 AVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIR 268
              Y+ +    +  +D++     Y ++   +     Q FL+ EQ   +    +++ Q I 
Sbjct: 90  CAFYKMM----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDII 143

Query: 269 DYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYL 328
           +       +  +    +  F     S    I++ ++  V QDMT+PLSHY+I+SSHNTYL
Sbjct: 144 EQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYL 203

Query: 329 TGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKE 388
            GDQ  S+S ++ Y   L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +
Sbjct: 204 VGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINK 263

Query: 389 HAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           +AFI +EYP+ILSIE++CS+ QQ++MA    D+ GD L L     ++ T+LPSP
Sbjct: 264 YAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSP 317



 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 43/104 (41%), Positives = 68/104 (65%), Gaps = 5/104 (4%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 473  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 528

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPD 1029
            ++++  QLSRIYP   R+DSSNYNP PFWN G QM   N  + D
Sbjct: 529  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMGVFNPNSED 572



 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 55/146 (37%), Positives = 78/146 (53%), Gaps = 15/146 (10%)

Query: 1059 YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRGTA-SPFVEVEIIGADYDSGV 1111
            +NP  +  + G++K   V LR+I  + L K        RG    PFVEVEIIG   D   
Sbjct: 566  FNPNSEDPLPGQLKKQLV-LRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCS- 623

Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
            +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +FIGQ T     +  
Sbjct: 624  REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DFIGQRTLAFSSMMP 682

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GYR V     + E +E +++ VH+++
Sbjct: 683  GYRHV-----YLEGMEEASIFVHVAV 703


>BC111985-1|AAI11986.1|  997|Homo sapiens phospholipase C-like 1
            protein.
          Length = 997

 Score =  215 bits (526), Expect = 6e-55
 Identities = 116/271 (42%), Positives = 163/271 (60%), Gaps = 9/271 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            R+ +E+SDL+  C+SV +    L +K   Y EM SF ET+A R+ ++    F V Y+   
Sbjct: 482  RLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDF-VNYNKKF 540

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYP   RIDSSN NP  FWNCG Q++A+N+QTP   M ++ G F QNGGCG++L+P 
Sbjct: 541  LSRIYPSAMRIDSSNLNPQDFWNCGCQIIAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS 600

Query: 1053 FMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTA-----SPFVEVEIIGAD 1106
             M +E  Y   + K I   V P+ + +++I  ++  K     A      P+V +EI G  
Sbjct: 601  IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP 660

Query: 1107 YDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPL 1166
             D   +  TKTV  N  NP++++  EF+V  PELA+IRFVV D+D  G+  FIGQ T P 
Sbjct: 661  ADCSEQR-TKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGD-EFIGQYTIPF 718

Query: 1167 LCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             CL+ GYR VPL +   + +E  TL VH++I
Sbjct: 719  ECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 749



 Score =  187 bits (455), Expect = 2e-46
 Identities = 125/442 (28%), Positives = 212/442 (47%), Gaps = 24/442 (5%)

Query: 11  DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGA- 69
           ++ I  A+  IS+++ G  + K  P  R   R   +  +   + W     P ++  E A 
Sbjct: 4   EKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWE----PSKKDLEKAK 59

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           LDI  +KE+R GK+++ F       +  E    F+I +G  ++      VA +      W
Sbjct: 60  LDISAIKEIRLGKNTETFRNNGLADQICEDC-AFSILHGENYE--SLDLVANSADVANIW 116

Query: 130 VKGVLYLIAEA------VSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPK-INCK 182
           V G+ YL++ +      +  +       WL+  F + +     I L++    L K +N  
Sbjct: 117 VSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPT 176

Query: 183 ISTSKLRDVFQDVDTEKRG---EIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTI 239
           +  +K+R  F+++   K      +  ++F   + +L        +++        N   +
Sbjct: 177 LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELC----TRPEVYFLLVQISKNKEYL 232

Query: 240 TLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSI 299
              +   FL  EQ      +++      R  L +  R   + +  +  F + L S +  I
Sbjct: 233 DANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQ--KGFLAIDGFTQYLLSSECDI 290

Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359
           +D +  KV QDMT+PLSHY+I++SHNTYL  DQF   + +  Y+R L+ GCR +ELD  D
Sbjct: 291 FDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSD 350

Query: 360 GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQ 419
           G D  P + + + +TT + F  V+  I + AF+ SEYPLIL + ++CSLPQQ+ MA   +
Sbjct: 351 GSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMK 410

Query: 420 DVFGDLLLVHPMDKNETSLPSP 441
            VFG+ L       +E+ LPSP
Sbjct: 411 KVFGNKLYTEAPLPSESYLPSP 432


>BC101531-1|AAI01532.1|  997|Homo sapiens phospholipase C-like 1
            protein.
          Length = 997

 Score =  215 bits (526), Expect = 6e-55
 Identities = 116/271 (42%), Positives = 163/271 (60%), Gaps = 9/271 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            R+ +E+SDL+  C+SV +    L +K   Y EM SF ET+A R+ ++    F V Y+   
Sbjct: 482  RLCRELSDLVSICKSVQYRDFELSMKSQNYWEMCSFSETEASRIANEYPEDF-VNYNKKF 540

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYP   RIDSSN NP  FWNCG Q++A+N+QTP   M ++ G F QNGGCG++L+P 
Sbjct: 541  LSRIYPSAMRIDSSNLNPQDFWNCGCQIIAMNFQTPGPMMDLHTGWFLQNGGCGYVLRPS 600

Query: 1053 FMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTA-----SPFVEVEIIGAD 1106
             M +E  Y   + K I   V P+ + +++I  ++  K     A      P+V +EI G  
Sbjct: 601  IMRDEVSYFSANTKGILPGVSPLALHIKIISGQNFPKPKGACAKGDVIDPYVCIEIHGIP 660

Query: 1107 YDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPL 1166
             D   +  TKTV  N  NP++++  EF+V  PELA+IRFVV D+D  G+  FIGQ T P 
Sbjct: 661  ADCSEQR-TKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGD-EFIGQYTIPF 718

Query: 1167 LCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             CL+ GYR VPL +   + +E  TL VH++I
Sbjct: 719  ECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 749



 Score =  187 bits (455), Expect = 2e-46
 Identities = 125/442 (28%), Positives = 212/442 (47%), Gaps = 24/442 (5%)

Query: 11  DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGA- 69
           ++ I  A+  IS+++ G  + K  P  R   R   +  +   + W     P ++  E A 
Sbjct: 4   EKKISSANDCISFMQAGCELKKVRPNSRIYNRFFTLDTDLQALRWE----PSKKDLEKAK 59

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           LDI  +KE+R GK+++ F       +  E    F+I +G  ++      VA +      W
Sbjct: 60  LDISAIKEIRLGKNTETFRNNGLADQICEDC-AFSILHGENYE--SLDLVANSADVANIW 116

Query: 130 VKGVLYLIAEA------VSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPK-INCK 182
           V G+ YL++ +      +  +       WL+  F + +     I L++    L K +N  
Sbjct: 117 VSGLRYLVSRSKQPLDFMEGNQNTPRFMWLKTVFEAADVDGNGIMLEDTSVELIKQLNPT 176

Query: 183 ISTSKLRDVFQDVDTEKRG---EIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTI 239
           +  +K+R  F+++   K      +  ++F   + +L        +++        N   +
Sbjct: 177 LKEAKIRLKFKEIQKSKEKLTTRVTEEEFCEAFCELC----TRPEVYFLLVQISKNKEYL 232

Query: 240 TLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSI 299
              +   FL  EQ      +++      R  L +  R   + +  +  F + L S +  I
Sbjct: 233 DANDLMLFLEAEQGVTHITEDICLDIIRRYELSEEGRQ--KGFLAIDGFTQYLLSSECDI 290

Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359
           +D +  KV QDMT+PLSHY+I++SHNTYL  DQF   + +  Y+R L+ GCR +ELD  D
Sbjct: 291 FDPEQKKVAQDMTQPLSHYYINASHNTYLIEDQFRGPADINGYIRALKMGCRSVELDVSD 350

Query: 360 GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQ 419
           G D  P + + + +TT + F  V+  I + AF+ SEYPLIL + ++CSLPQQ+ MA   +
Sbjct: 351 GSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNHCSLPQQKVMAQQMK 410

Query: 420 DVFGDLLLVHPMDKNETSLPSP 441
            VFG+ L       +E+ LPSP
Sbjct: 411 KVFGNKLYTEAPLPSESYLPSP 432


>BC036392-1|AAH36392.1| 1001|Homo sapiens phospholipase C-like 2
           protein.
          Length = 1001

 Score =  211 bits (516), Expect = 1e-53
 Identities = 139/443 (31%), Positives = 226/443 (51%), Gaps = 26/443 (5%)

Query: 11  DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGA- 69
           ++ I  A   I+ +  GS + K     R   R   +  +   + W     P ++  E A 
Sbjct: 4   EKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWE----PSKKDSEKAK 59

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           +DI+ +KEVRTGK++ D  R    + R+     F++ YG  ++      VA +      W
Sbjct: 60  IDIKSIKEVRTGKNT-DIFRSNGISDRISEDCAFSVIYGENYE--SLDLVANSADVANIW 116

Query: 130 VKGVLYLIA------EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCK 182
           V G+ YLI+      + + +S       W+ + F  I+ ++   ITL      +  +N  
Sbjct: 117 VTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPG 176

Query: 183 ISTSKLRDVFQDV--DTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTI 239
           + TSK+   F+++    +K G E+  ++F  ++ +L        +I+     + SN   +
Sbjct: 177 LKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELC----TRPEIYFLLVQFSSNKEFL 232

Query: 240 TLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFVEMLYSKQNS 298
             ++   FL  EQ     ++E+   + I  Y  +P ++  E  + ++  F   L S    
Sbjct: 233 DTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGFTNYLMSPDCY 289

Query: 299 IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCW 358
           I+D ++ KV QDM +PLSHY+I+SSHNTYL  DQF   S +  Y+R L+ GCR +ELD W
Sbjct: 290 IFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVW 349

Query: 359 DGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAF 418
           DGPD  P IY GHT+T++I F  V+  I ++AF  SEYPLIL +E++CS+ QQ+ M    
Sbjct: 350 DGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHM 409

Query: 419 QDVFGDLLLVHPMDKNETSLPSP 441
           + + GD L     +  E+ LPSP
Sbjct: 410 KKLLGDKLYTTSPNVEESYLPSP 432



 Score =  192 bits (469), Expect = 5e-48
 Identities = 108/275 (39%), Positives = 163/275 (59%), Gaps = 11/275 (4%)

Query: 930  RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            + +++ KE+S+L+  C+SV F   ++  +   Y E+ SF E  A +  ++    F V Y+
Sbjct: 484  KRFQLCKELSELVSICKSVQFKEFQMSFQVQKYWEVCSFNEVLASKYANENPGDF-VNYN 542

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
               L+R++P   RIDSSN NP  FW CG Q+VA+N+QTP   M +N+G F+QNG CG++L
Sbjct: 543  KRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVL 602

Query: 1050 KPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEI 1102
            +P  M EE   ++   K S+ G V P  + +++I  ++  K  G G       P+V VEI
Sbjct: 603  RPAIMREEVSFFSVNTKDSVPG-VSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEI 661

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
             G   D   +  TKTV  NG   ++++  EF++  PELA++RFVV D+D  G+  FIGQ 
Sbjct: 662  HGIPADCAEQR-TKTVHQNGDAHIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQY 719

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            T P  CL+ GYR VPL +   E L  ++L VH++I
Sbjct: 720  TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI 754


>AB029015-1|BAA83044.1| 1154|Homo sapiens KIAA1092 protein protein.
          Length = 1154

 Score =  211 bits (515), Expect = 1e-53
 Identities = 141/453 (31%), Positives = 231/453 (50%), Gaps = 27/453 (5%)

Query: 2   KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    ++ I  A   I+ +  GS + K     R   R   +  +   + W     
Sbjct: 147 KTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWE---- 202

Query: 61  PQRQGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119
           P ++  E A +DI+ +KEVRTGK++ D  R    + ++     F++ YG  ++      V
Sbjct: 203 PSKKDSEKAKIDIKSIKEVRTGKNT-DIFRSNGISDQISEDCAFSVIYGENYE--SLDLV 259

Query: 120 AQTDKECEAWVKGVLYLIA------EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEV 172
           A +      WV G+ YLI+      + + +S       W+ + F  I+ ++   ITL   
Sbjct: 260 ANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNA 319

Query: 173 KAFLPKINCKISTSKLRDVFQDV--DTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFDKY 229
              +  +N  + TSK+   F+++    +K G E+  ++F  ++ +L        +I+   
Sbjct: 320 VQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELC----TRPEIYFLL 375

Query: 230 SVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEF 288
             + SN   +  ++   FL  EQ     ++E+   + I  Y  +P ++  E  + ++  F
Sbjct: 376 VQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF 432

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
              L S    I+D ++ KV QDM +PLSHY+I+SSHNTYL  DQF   S +  Y+R L+ 
Sbjct: 433 TNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKM 492

Query: 349 GCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSL 408
           GCR +ELD WDGPD  P IY GHT+T++I F  V+  I ++AF  SEYPLIL +E++CS+
Sbjct: 493 GCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSI 552

Query: 409 PQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
            QQ+ M    + + GD L     +  E+ LPSP
Sbjct: 553 KQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSP 585



 Score =  196 bits (478), Expect = 4e-49
 Identities = 109/275 (39%), Positives = 164/275 (59%), Gaps = 11/275 (4%)

Query: 930  RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            + +++ KE+S+L+  C+SV F   ++  +   Y E+ SF E  A +  ++    F V Y+
Sbjct: 637  KRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDF-VNYN 695

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
               L+R++P   RIDSSN NP  FW CG Q+VA+N+QTP   M +N+G F+QNG CG++L
Sbjct: 696  KRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVL 755

Query: 1050 KPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEI 1102
            +P  M EE   ++   K S+ G V P  + +++I  ++  K  G G       P+V VEI
Sbjct: 756  RPAIMREEVSFFSANTKDSVPG-VSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEI 814

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
             G   D   +  TKTV  NG  P++++  EF++  PELA++RFVV D+D  G+  FIGQ 
Sbjct: 815  HGIPADCAEQR-TKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQY 872

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            T P  CL+ GYR VPL +   E L  ++L VH++I
Sbjct: 873  TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI 907


>BC010668-1|AAH10668.2|  617|Homo sapiens PLCD3 protein protein.
          Length = 617

 Score =  210 bits (514), Expect = 2e-53
 Identities = 115/330 (34%), Positives = 175/330 (53%), Gaps = 11/330 (3%)

Query: 148 QIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFD 206
           +++ W+    +  + N   K++ KE+K+ L  +N  ++      +F++ D      +   
Sbjct: 10  RLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECDHSNNDRLEGA 69

Query: 207 DFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQF 266
           +     ++L+     +++IF +YS        ++  E   FL D+  +  G    +A Q 
Sbjct: 70  EIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE--GATLARAQQL 123

Query: 267 IRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNT 326
           I+ Y  +     +E   TL  F+  L S + +  D+ +  V QDM +PL+HY+ISSSHNT
Sbjct: 124 IQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLAHYFISSSHNT 182

Query: 327 YLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTI 386
           YLT  Q    SS EAYVR    GCRC+ELDCW+GP G P IYHGHTLT+KI F DV++ +
Sbjct: 183 YLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAV 242

Query: 387 KEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NETSLPSPHDXX 445
           ++HAF  S YP+ILS+E++C L QQ  MA     + GD+L+   +D  N   LPSP    
Sbjct: 243 RDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNPEELPSPEQLK 302

Query: 446 XXXXXXXXXXPEGAEESSFAV--RQEEGKD 473
                     P    E   A+  R+EE +D
Sbjct: 303 GRVLVKGKKLPAARSEDGRALSDREEEEED 332



 Score =  168 bits (408), Expect = 1e-40
 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I+ E+S L +YC +                ++SS  E KA++L+ +  N+F V+++  Q
Sbjct: 351  QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 409

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L+R+YP G R++S+NY+P   WN G Q+VALN+QTP   M +N G+F  NG CG++LKP 
Sbjct: 410  LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 469

Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107
             + +    P      E    P  T+ ++V+ A+ L K           P V +EI G   
Sbjct: 470  CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 525

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   +  T  V +NG NP W    +F++  PELAL+RFVV+D D     +F+GQ T PL 
Sbjct: 526  DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 584

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L++GYR + L +     L  +TL + + I
Sbjct: 585  SLKQGYRHIHLLSKDGASLSPATLFIQIRI 614


>AK074149-1|BAB84975.1|  656|Homo sapiens FLJ00222 protein protein.
          Length = 656

 Score =  204 bits (498), Expect = 1e-51
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 60   RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 115

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 116  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 175

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 176  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 234

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 235  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 292

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 293  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 326


>BC125067-1|AAI25068.1|  415|Homo sapiens PLCZ1 protein protein.
          Length = 415

 Score =  196 bits (479), Expect = 3e-49
 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 145  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 203

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 204  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 261

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 262  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 317

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 318  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 376

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 377  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 411



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 24/51 (47%), Positives = 33/51 (64%)

Query: 391 FITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           F TS+YP++LS+E++CS  QQ  MA   Q  FG+ LL   +D    +LPSP
Sbjct: 44  FKTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 94


>AK097725-1|BAC05152.1|  390|Homo sapiens protein ( Homo sapiens cDNA
            FLJ40406 fis, clone TESTI2037534, weakly similar to
            1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE
            DELTA ).
          Length = 390

 Score =  196 bits (479), Expect = 3e-49
 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 120  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 178

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 179  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 236

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 237  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 292

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 293  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 351

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 352  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 386


>AK022610-1|BAB14129.1|  466|Homo sapiens protein ( Homo sapiens cDNA
            FLJ12548 fis, clone NT2RM4000657, weakly similar to
            1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE
            DELTA ).
          Length = 466

 Score =  196 bits (479), Expect = 3e-49
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 42   RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 98

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 99   -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 157

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 158  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 216

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 217  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 274

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 275  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 307


>AF532185-1|AAN71895.1|  608|Homo sapiens PLC-zeta protein.
          Length = 608

 Score =  196 bits (479), Expect = 3e-49
 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 338  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 396

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 397  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 454

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 455  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 510

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 511  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 569

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 570  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 604



 Score =  196 bits (478), Expect = 4e-49
 Identities = 102/277 (36%), Positives = 161/277 (58%), Gaps = 8/277 (2%)

Query: 166 KITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI 225
           KI L++ +  L K++ + S   ++ +F+D D  K+G I  ++F  +Y ++I     + +I
Sbjct: 18  KINLEKTQRLLEKLDIRCSYIHVKQIFKDNDRLKQGRITIEEFRAIY-RIITHREEIIEI 76

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPY-FT 284
           F+ YS    N   +       FL  EQ+       + A + I+ Y  +P  ++ + +  +
Sbjct: 77  FNTYS---ENRKILLASNLAQFLTQEQYAAEMSKAI-AFEIIQKY--EPIEEVRKAHQMS 130

Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344
           L  F   + S++  ++ ++  KV QDMT PL+ Y+ISSSHNTYL  DQ    S L  YV 
Sbjct: 131 LEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVS 190

Query: 345 CLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404
            L  GCRC+E+DCWDG    P +YHG+TLT+K+ F  V++ I ++AF+TS+YP++LS+E+
Sbjct: 191 ALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLEN 250

Query: 405 NCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           +CS  QQ  MA   Q  FG+ LL   +D    +LPSP
Sbjct: 251 HCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 287


>AB028992-1|BAA83021.1|  787|Homo sapiens KIAA1069 protein protein.
          Length = 787

 Score =  196 bits (479), Expect = 3e-49
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 375  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 431

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 432  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 490

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 491  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 549

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 550  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 607

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 608  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 640



 Score =  184 bits (448), Expect = 2e-45
 Identities = 89/212 (41%), Positives = 134/212 (63%), Gaps = 5/212 (2%)

Query: 232 YCSNGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
           Y      +T+ E   FL+ EQ  +N+  D       I+ +    +  + +    +  F  
Sbjct: 9   YSDKKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTN 65

Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350
            + S    I++  + +V QDM +PL +Y+I+SSHNTYLTGDQ  S+S ++ Y R L+ GC
Sbjct: 66  FMRSPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGC 125

Query: 351 RCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQ 410
           RC+E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ Q
Sbjct: 126 RCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQ 185

Query: 411 QRRMASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           QR++A   + +FGD L +  +D  E   LPSP
Sbjct: 186 QRKIAQYLKGIFGDKLDLSSVDTGECKQLPSP 217


>AK023546-1|BAB14606.1|  677|Homo sapiens protein ( Homo sapiens cDNA
            FLJ13484 fis, clone PLACE1003888, weakly similar to
            1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE
            DELTA ).
          Length = 677

 Score =  196 bits (478), Expect = 4e-49
 Identities = 109/275 (39%), Positives = 164/275 (59%), Gaps = 11/275 (4%)

Query: 930  RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            + +++ KE+S+L+  C+SV F   ++  +   Y E+ SF E  A +  ++    F V Y+
Sbjct: 201  KRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDF-VNYN 259

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
               L+R++P   RIDSSN NP  FW CG Q+VA+N+QTP   M +N+G F+QNG CG++L
Sbjct: 260  KRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVL 319

Query: 1050 KPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEI 1102
            +P  M EE   ++   K S+ G V P  + +++I  ++  K  G G       P+V VEI
Sbjct: 320  RPAIMREEVSFFSANTKDSVPG-VSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEI 378

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
             G   D   +  TKTV  NG  P++++  EF++  PELA++RFVV D+D  G+  FIGQ 
Sbjct: 379  HGIPADCAEQR-TKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQY 436

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            T P  CL+ GYR VPL +   E L  ++L VH++I
Sbjct: 437  TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI 471



 Score =  162 bits (393), Expect = 8e-39
 Identities = 72/143 (50%), Positives = 97/143 (67%)

Query: 299 IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCW 358
           I+D ++ KV QDM +PLSHY+I+SSHNTYL  DQF   S +  Y+R L+ GCR +ELD W
Sbjct: 7   IFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVW 66

Query: 359 DGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAF 418
           DGPD  P IY GHT+T++I F  V+  I ++AF  SEYPLIL +E++CS+ QQ+ M    
Sbjct: 67  DGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHM 126

Query: 419 QDVFGDLLLVHPMDKNETSLPSP 441
           + + GD L     +  E+ LPSP
Sbjct: 127 KKLLGDKLYTTSPNVEESYLPSP 149


>AY035866-1|AAK61372.1|  504|Homo sapiens testis-development related
            NYD-SP27 protein.
          Length = 504

 Score =  194 bits (474), Expect = 1e-48
 Identities = 111/275 (40%), Positives = 159/275 (57%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 234  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 292

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 293  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 350

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+     L  T          V +
Sbjct: 351  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLTSGIQLPLTHSSSNKGDSLVII 406

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 407  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 465

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 466  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 500



 Score =  165 bits (400), Expect = 1e-39
 Identities = 78/180 (43%), Positives = 115/180 (63%), Gaps = 3/180 (1%)

Query: 263 ASQFIRDYLRDPQRDIYEPY-FTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWIS 321
           A + I+ Y  +P  ++ + +  +L  F   + S++  ++ ++  KV QDMT PL+ Y+IS
Sbjct: 6   AFEIIQKY--EPIEEVRKAHQMSLEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFIS 63

Query: 322 SSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMD 381
           SSHNTYL  DQ    S L  YV  L  GCRC+E+DCWDG    P +YHG+TLT+K+ F  
Sbjct: 64  SSHNTYLVSDQLLGPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKT 123

Query: 382 VLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           V++ I ++AF+TS+YP++LS+E++CS  QQ  MA   Q  FG+ LL   +D    +LPSP
Sbjct: 124 VIQAIHKYAFMTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 183


>BC117458-1|AAI17459.1| 1175|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1175

 Score =  180 bits (437), Expect = 4e-44
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>AL031652-3|CAI42218.2| 1194|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1194

 Score =  180 bits (437), Expect = 4e-44
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>AL031652-2|CAI42213.1| 1175|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1175

 Score =  180 bits (437), Expect = 4e-44
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>AL023805-6|CAI43092.2| 1194|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1194

 Score =  180 bits (437), Expect = 4e-44
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>AL023805-5|CAI43087.1| 1175|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1175

 Score =  180 bits (437), Expect = 4e-44
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>AL031652-4|CAI42214.1| 1023|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1023

 Score =  173 bits (420), Expect = 4e-42
 Identities = 104/254 (40%), Positives = 149/254 (58%), Gaps = 21/254 (8%)

Query: 205 FDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD----- 258
           ++ F  L QK I    +++D+F K  +       +T+ +  +FL + Q D  L +     
Sbjct: 42  YEKFYELTQK-ICPRTDIEDLFKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPF 98

Query: 259 -DEVQASQFIRDYLRDPQRDIYEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
            D  +A Q I  Y  +P  D+ +     S+ F   L S +N+       ++ Q+M  PL+
Sbjct: 99  YDAKRAMQIIEMY--EPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLA 156

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLT 374
           HY+ISSSHNTYLTG QF  +SS+E Y + L +GCRC+ELDCWD  G D  P I HG  + 
Sbjct: 157 HYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMC 216

Query: 375 TKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VH 429
           T I F DV++ IKE AF+TSEYP+ILS E++CS  QQ +M+   +D+FGDLLL      H
Sbjct: 217 TDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESH 276

Query: 430 PMDKNETSLPSPHD 443
           P++    +LPSP+D
Sbjct: 277 PLEPGR-ALPSPND 289



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 406  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 464

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 465  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 524

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 525  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 580

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 581  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 636

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 637  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 670


>AL023805-7|CAI43088.1| 1023|Homo sapiens phospholipase C, beta 4
           protein.
          Length = 1023

 Score =  173 bits (420), Expect = 4e-42
 Identities = 104/254 (40%), Positives = 149/254 (58%), Gaps = 21/254 (8%)

Query: 205 FDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD----- 258
           ++ F  L QK I    +++D+F K  +       +T+ +  +FL + Q D  L +     
Sbjct: 42  YEKFYELTQK-ICPRTDIEDLFKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPF 98

Query: 259 -DEVQASQFIRDYLRDPQRDIYEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
            D  +A Q I  Y  +P  D+ +     S+ F   L S +N+       ++ Q+M  PL+
Sbjct: 99  YDAKRAMQIIEMY--EPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLA 156

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLT 374
           HY+ISSSHNTYLTG QF  +SS+E Y + L +GCRC+ELDCWD  G D  P I HG  + 
Sbjct: 157 HYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMC 216

Query: 375 TKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VH 429
           T I F DV++ IKE AF+TSEYP+ILS E++CS  QQ +M+   +D+FGDLLL      H
Sbjct: 217 TDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESH 276

Query: 430 PMDKNETSLPSPHD 443
           P++    +LPSP+D
Sbjct: 277 PLEPGR-ALPSPND 289



 Score =  166 bits (403), Expect = 5e-40
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 406  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 464

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 465  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 524

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 525  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 580

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 581  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 636

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 637  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 670


>L41349-1|AAB02027.1| 1022|Homo sapiens phospholipase C beta 4
           protein.
          Length = 1022

 Score =  172 bits (418), Expect = 7e-42
 Identities = 104/254 (40%), Positives = 148/254 (58%), Gaps = 21/254 (8%)

Query: 205 FDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD----- 258
           ++ F  L QK I    +++D+F K  +       +T+ +  +FL + Q D  L +     
Sbjct: 53  YEKFYELTQK-ICPRTDIEDLFKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPF 109

Query: 259 -DEVQASQFIRDYLRDPQRDIYEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
            D  +A Q I  Y  +P  D+ +     S+ F   L S +N+       ++ Q+M  PL+
Sbjct: 110 YDAKRAMQIIEMY--EPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLA 167

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLT 374
           HY+ISSSHNTYLTG QF  +SS+E Y + L +GCRC+ELDCWD  G D  P I HG  + 
Sbjct: 168 HYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMC 227

Query: 375 TKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VH 429
           T I F DV++ IKE AF+TSEYP+ILS E++CS  QQ +M+   +D+FGDLLL      H
Sbjct: 228 TDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESH 287

Query: 430 PMDKNETSLPSPHD 443
           P++     LPSP+D
Sbjct: 288 PLEPGR-PLPSPND 300



 Score =  165 bits (401), Expect = 8e-40
 Identities = 104/274 (37%), Positives = 154/274 (56%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 405  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 463

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 464  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 523

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 524  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 579

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+  +   +V  P+LA++R  V D++       IGQ   P
Sbjct: 580  TIRKEFRTRMVMNNGLNPVYNEESLVFRKVILPDLAVLRIAVYDDN----NKLIGQRIPP 635

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 636  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 669


>AL389885-3|CAH73289.1| 1994|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 1994

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1062 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1120

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1121 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1180

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1181 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1220



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1449 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1507

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1508 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1567

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1568 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1625

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1626 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1676


>AL389885-2|CAH73288.1| 2312|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 2312

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>AL365510-3|CAH73758.1| 1994|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 1994

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1062 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1120

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1121 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1180

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1181 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1220



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1449 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1507

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1508 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1567

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1568 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1625

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1626 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1676


>AL365510-2|CAH73757.1| 2312|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 2312

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>AL139124-2|CAI16675.1| 1994|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 1994

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1062 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1120

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1121 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1180

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1181 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1220



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1449 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1507

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1508 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1567

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1568 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1625

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1626 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1676


>AL139124-1|CAI16674.1| 2312|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 2312

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>AL139118-2|CAH70740.1| 1994|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 1994

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1062 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1120

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1121 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1180

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1181 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1220



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1449 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1507

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1508 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1567

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1568 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1625

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1626 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1676


>AL139118-1|CAH70739.1| 2312|Homo sapiens phospholipase C, epsilon 1
            protein.
          Length = 2312

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>AF170071-1|AAG28341.1| 1994|Homo sapiens phospholipase C epsilon
            protein.
          Length = 1994

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1062 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1120

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1121 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1180

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1181 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1220



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1449 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1507

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1508 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1567

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1568 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1625

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1626 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1676


>AF117948-1|AAF22005.1| 1103|Homo sapiens pancreas-enriched
           phospholipase C protein.
          Length = 1103

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288 FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
           F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 171 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 229

Query: 346 LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 230 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 289

Query: 406 CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
           CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 290 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 329



 Score =  146 bits (354), Expect = 4e-34
 Identities = 83/234 (35%), Positives = 127/234 (54%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +      +++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 558  ISSLNENAAKRLCRRYSQKL-IQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 616

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 617  YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 676

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 677  VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFRVHFEDL 734

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 735  VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 785


>AB040949-1|BAA96040.2| 2304|Homo sapiens KIAA1516 protein protein.
          Length = 2304

 Score =  167 bits (405), Expect = 3e-40
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1372 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1430

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1431 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1490

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1491 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1530



 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1759 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1817

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1818 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1877

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1878 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFRVHFEDL 1935

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1936 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1986


>BC117231-1|AAI17232.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>BC069420-1|AAH69420.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AY004175-1|AAF86613.1| 1211|Homo sapiens phospholipase C beta 1
            protein.
          Length = 1211

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 533  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 588

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 589  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 648

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 649  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 704

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 705  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 760

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 761  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 790



 Score =  151 bits (365), Expect = 2e-35
 Identities = 112/404 (27%), Positives = 199/404 (49%), Gaps = 40/404 (9%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLE-------SSKCFTIYYGTEF-KLRCASFVAQ 121
           LD+  VK+ R G+ +K   + P+  + L+         +  T+ YG +   +   + VA 
Sbjct: 59  LDLSLVKDARCGRHAKA-PKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLVAF 117

Query: 122 TDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVKAFLPK 178
            ++  + W   V  L    ++ +  +  + +L K +  ++       +I LK +      
Sbjct: 118 QEEVAKEWTNEVFSLATNLLAQN--MSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA 175

Query: 179 INCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDE----NNVQDIFDKYSVYCS 234
              ++ T+        + + +   I  +DF     ++ F+       + +IF ++     
Sbjct: 176 DRKRVETAMEAC---SLPSSRNDSILQEDFTPEVYRVFFNNLCLRPEIDNIFSEFGA--K 230

Query: 235 NGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYEP-YFTLS 286
           +   +T+ +  +F+  +Q D  L +       + Q    I  Y  +P   +      ++ 
Sbjct: 231 SKPYLTVDQMMDFINLKQRDPRLNEILYPPPKQEQVQVLIEKY--EPNNSLARKGQISVD 288

Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346
            F+  L  ++N +  ++   + +DM+RPLSHY+I+SSHNTYLT  Q +  SS+E Y + L
Sbjct: 289 GFMRYLSGEENGVVSTEKLDLNEDMSRPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQAL 348

Query: 347 RSGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404
            SGCRC+ELDCW G   +  P I HG T+TT+I F +V++ I E AF TS +P++LS E+
Sbjct: 349 LSGCRCVELDCWRGRTAEEEPVITHGFTMTTEISFKEVIKAIAECAFKTSPFPILLSFEN 408

Query: 405 NCSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
           +   P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 409 HVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 452


>AL137267-1|CAB70666.1|  913|Homo sapiens hypothetical protein
            protein.
          Length = 913

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 278  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 333

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 334  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 393

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 394  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 449

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 450  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 505

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 506  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 535



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 35  FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 94

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 95  SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 154

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 155 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 197


>AL050323-3|CAI22831.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL050323-2|CAI22830.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL050315-2|CAI42239.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL050315-1|CAI42238.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL049632-2|CAI43152.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL049632-1|CAI43151.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL049593-1|CAI22175.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL034551-2|CAI21974.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL034551-1|CAI21973.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL031683-3|CAI43122.1| 1173|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AL031683-2|CAI43121.1| 1216|Homo sapiens phospholipase C, beta 1
            (phosphoinositide-specific) protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AK023689-1|BAB14641.1|  639|Homo sapiens protein ( Homo sapiens cDNA
            FLJ13627 fis, clone PLACE1011046, highly similar to
            1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE
            BETA ).
          Length = 639

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 115  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 170

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 171  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 230

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 231  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 286

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 287  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 342

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 343  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 372


>AJ278314-1|CAB98143.1| 1173|Homo sapiens phospholipase C-beta-1b
            protein.
          Length = 1173

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AJ278313-1|CAB98142.1| 1216|Homo sapiens phospholipase C-beta-1a
            protein.
          Length = 1216

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>AB011153-1|BAA25507.3| 1218|Homo sapiens KIAA0581 protein protein.
          Length = 1218

 Score =  165 bits (400), Expect = 1e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 540  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 595

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 596  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 655

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 656  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 711

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 712  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 767

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 768  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 797



 Score =  147 bits (355), Expect = 3e-34
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 297 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 356

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 357 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 416

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 417 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 459


>AF190642-1|AAG17145.2| 2303|Homo sapiens phosphoinositide-specific
            phospholipase C PLC-epsilon protein.
          Length = 2303

 Score =  164 bits (398), Expect = 2e-39
 Identities = 81/160 (50%), Positives = 106/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHT TTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTPTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  146 bits (354), Expect = 4e-34
 Identities = 83/234 (35%), Positives = 127/234 (54%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +      +++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-IQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFRVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>AK097555-1|BAC05099.1|  403|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40236 fis, clone TESTI2023214, weakly similar to
           1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE
           PHOSPHODIESTERASE DELTA ).
          Length = 403

 Score =  161 bits (391), Expect = 1e-38
 Identities = 72/148 (48%), Positives = 100/148 (67%)

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S++  ++ ++  KV QDMT PL+ Y+ISSSHNTYL  DQ    S L  YV  L  GCRC+
Sbjct: 3   SRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVSALVKGCRCL 62

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDG    P +YHG+TLT+K+ F  V++ I ++AF+TS+YP++LS+E++CS  QQ  
Sbjct: 63  EIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENHCSTAQQEV 122

Query: 414 MASAFQDVFGDLLLVHPMDKNETSLPSP 441
           MA   Q  FG+ LL   +D    +LPSP
Sbjct: 123 MADNLQATFGESLLSDMLDDFPDTLPSP 150



 Score =  128 bits (310), Expect = 9e-29
 Identities = 80/202 (39%), Positives = 114/202 (56%), Gaps = 14/202 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 201  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 259

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 260  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 317

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 318  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 373

Query: 1101 EIIGADYDSGVKLVTKTVSDNG 1122
            E+ G   D  +K  T+ +  NG
Sbjct: 374  EVFGVPNDQ-MKQQTRVIKKNG 394


>AB209599-1|BAD92836.1|  279|Homo sapiens phospholipase C, delta 4
            variant protein.
          Length = 279

 Score =  159 bits (386), Expect = 6e-38
 Identities = 88/201 (43%), Positives = 119/201 (59%), Gaps = 11/201 (5%)

Query: 985  FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
            FV+++T QLSR+YP G R DSSNYNP   WN G QMVA+N QT    M +  G F+QNGG
Sbjct: 30   FVQHNTWQLSRVYPSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGG 89

Query: 1045 CGFILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGT-ASPFV 1098
            CG++LKP F+   +  ++P  +K I    K  T++++VI  + L    KT  G+   P V
Sbjct: 90   CGYVLKPDFLRDIQSSFHP--EKPI-SPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLV 146

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            +V+I G   D+  +  T  V +NG NP W     F V  PELA++RFVV D D     +F
Sbjct: 147  KVQIFGVRLDT-ARQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDF 205

Query: 1159 IGQATFPLLCLRKGYRSVPLT 1179
            IGQ T P  C+++G    PLT
Sbjct: 206  IGQYTLPWTCMQQG-EPAPLT 225


>Z37544-1|CAA85776.1| 1234|Homo sapiens phospholipase C beta 3
            protein.
          Length = 1234

 Score =  156 bits (378), Expect = 5e-37
 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y   V F + E  R +   + EMSSF ETKA   +++    F V+Y+  QLS
Sbjct: 588  EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 645

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNY P  FWN G Q+VALN+QT D  MQ+N G F+ NG  G++LKP+FM
Sbjct: 646  RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 705

Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  +  ++G V    + ++VI  + L     G    +VEV++ G   D+  K
Sbjct: 706  RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 761

Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
              T+T   N  NP+W+ +  +F +V  P LA +R    +E       F+G    P+  +R
Sbjct: 762  YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 817

Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194
             GY  V L N  ++ L L  L+++
Sbjct: 818  SGYHYVCLRNEANQPLCLPALLIY 841



 Score =  150 bits (363), Expect = 3e-35
 Identities = 123/407 (30%), Positives = 198/407 (48%), Gaps = 45/407 (11%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETK------------RLESSKCFTIYYGTE-FKLRCA 116
           LDI  +++ RTG+    + R P++ K            RLE  K  T+  G +       
Sbjct: 64  LDISSIRDTRTGR----YARLPKDPKIREVLGFGGPDARLEE-KLMTVVSGPDPVNTVFL 118

Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVK 173
           +F+A  D   + W +  L+ +A  + A    +   +LRK +  ++   N   +I +K + 
Sbjct: 119 NFMAVQDDTAKVWSEE-LFKLAMNILAQNASR-NTFLRKAYTKLKLQVNQDGRIPVKNIL 176

Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY--SV 231
                   ++ T+ L      +   +   I  D+F++   +   ++  ++   DK    +
Sbjct: 177 KMFSADKKRVETA-LESC--GLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEI 233

Query: 232 YCSNGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYF 283
                  +TL +  +F+  +Q D   ++ +       QA   I  Y  +P +   E    
Sbjct: 234 GAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQM 291

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
           ++  F   L  ++N I   +   ++ DMT+PLS Y+I+SSHNTYLT  Q +  SS+E Y 
Sbjct: 292 SMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYR 351

Query: 344 RCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           + L  GCRC+ELD W G  P+  PFI HG T+TT++   DVL  I E AF TS YP+ILS
Sbjct: 352 QALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILS 411

Query: 402 IEDNC-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
            E++  S  QQ +MA   + +FGD LL+ P+DK   +    LPSP D
Sbjct: 412 FENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 458


>Z16411-1|CAA78903.1| 1051|Homo sapiens phospholipase c protein.
          Length = 1051

 Score =  156 bits (378), Expect = 5e-37
 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y   V F + E  R +   + EMSSF ETKA   +++    F V+Y+  QLS
Sbjct: 405  EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 462

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNY P  FWN G Q+VALN+QT D  MQ+N G F+ NG  G++LKP+FM
Sbjct: 463  RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 522

Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  +  ++G V    + ++VI  + L     G    +VEV++ G   D+  K
Sbjct: 523  RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 578

Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
              T+T   N  NP+W+ +  +F +V  P LA +R    +E       F+G    P+  +R
Sbjct: 579  YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 634

Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194
             GY  V L N  ++ L L  L+++
Sbjct: 635  SGYHYVCLRNEANQPLCLPALLIY 658



 Score =  149 bits (362), Expect = 4e-35
 Identities = 88/220 (40%), Positives = 125/220 (56%), Gaps = 17/220 (7%)

Query: 239 ITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYFTLSEFVE 290
           +TL +  +F+  +Q D   ++ +       QA   I  Y  +P +   E    ++  F  
Sbjct: 58  LTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQMSMEGFSR 115

Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350
            L  ++N I   +   ++ DMT+PLS Y+I+SSHNTYLT  Q +  SS+E Y + L  GC
Sbjct: 116 YLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGC 175

Query: 351 RCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-S 407
           RC+ELD W G  P+  PFI HG T+TT++   DVL  I E AF TS YP+ILS E++  S
Sbjct: 176 RCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDS 235

Query: 408 LPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
             QQ +MA   + +FGD LL+ P+DK   +    LPSP D
Sbjct: 236 AKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 275


>U26425-1|AAA77683.1| 1234|Homo sapiens phospholipase C-beta-3
            protein.
          Length = 1234

 Score =  156 bits (378), Expect = 5e-37
 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y   V F + E  R +   + EMSSF ETKA   +++    F V+Y+  QLS
Sbjct: 588  EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 645

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNY P  FWN G Q+VALN+QT D  MQ+N G F+ NG  G++LKP+FM
Sbjct: 646  RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 705

Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  +  ++G V    + ++VI  + L     G    +VEV++ G   D+  K
Sbjct: 706  RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 761

Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
              T+T   N  NP+W+ +  +F +V  P LA +R    +E       F+G    P+  +R
Sbjct: 762  YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 817

Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194
             GY  V L N  ++ L L  L+++
Sbjct: 818  SGYHYVCLRNEANQPLCLPALLIY 841



 Score =  150 bits (363), Expect = 3e-35
 Identities = 123/407 (30%), Positives = 198/407 (48%), Gaps = 45/407 (11%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETK------------RLESSKCFTIYYGTE-FKLRCA 116
           LDI  +++ RTG+    + R P++ K            RLE  K  T+  G +       
Sbjct: 64  LDISSIRDTRTGR----YARLPKDPKIREVLGFGGPDARLEE-KLMTVVSGPDPVNTVFL 118

Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVK 173
           +F+A  D   + W +  L+ +A  + A    +   +LRK +  ++   N   +I +K + 
Sbjct: 119 NFMAVQDDTAKVWSEE-LFKLAMNILAQNASR-NTFLRKAYTKLKLQVNQDGRIPVKNIL 176

Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY--SV 231
                   ++ T+ L      +   +   I  D+F++   +   ++  ++   DK    +
Sbjct: 177 KMFSADKKRVETA-LESC--GLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEI 233

Query: 232 YCSNGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYF 283
                  +TL +  +F+  +Q D   ++ +       QA   I  Y  +P +   E    
Sbjct: 234 GAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQM 291

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
           ++  F   L  ++N I   +   ++ DMT+PLS Y+I+SSHNTYLT  Q +  SS+E Y 
Sbjct: 292 SMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYR 351

Query: 344 RCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           + L  GCRC+ELD W G  P+  PFI HG T+TT++   DVL  I E AF TS YP+ILS
Sbjct: 352 QALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILS 411

Query: 402 IEDNC-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
            E++  S  QQ +MA   + +FGD LL+ P+DK   +    LPSP D
Sbjct: 412 FENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 458


>BC032659-1|AAH32659.1| 1191|Homo sapiens Similar to phospholipase C,
            beta 3 (phosphatidylinositol-specific) protein.
          Length = 1191

 Score =  156 bits (378), Expect = 5e-37
 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y   V F + E  R +   + EMSSF ETKA   +++    F V+Y+  QLS
Sbjct: 545  EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 602

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNY P  FWN G Q+VALN+QT D  MQ+N G F+ NG  G++LKP+FM
Sbjct: 603  RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 662

Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  +  ++G V    + ++VI  + L     G    +VEV++ G   D+  K
Sbjct: 663  RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 718

Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
              T+T   N  NP+W+ +  +F +V  P LA +R    +E       F+G    P+  +R
Sbjct: 719  YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 774

Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194
             GY  V L N  ++ L L  L+++
Sbjct: 775  SGYHYVCLRNEANQPLCLPALLIY 798



 Score =  150 bits (364), Expect = 3e-35
 Identities = 119/396 (30%), Positives = 190/396 (47%), Gaps = 35/396 (8%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTE-FKLRCASFVAQTDKECE 127
           AL +     V T +    F +W EE       K  T+  G +       +F+A  D   +
Sbjct: 34  ALQLEPPTVVETLRRGSKFIKWDEE-------KLMTVVSGPDPVNTVFLNFMAVQDDTAK 86

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVKAFLPKINCKIS 184
            W +  L+ +A  + A    +   +LRK +  ++   N   +I +K +         ++ 
Sbjct: 87  VWSEE-LFKLAMNILAQNASR-NTFLRKAYTKLKLQVNQDGRIPVKNILKMFSADKKRVE 144

Query: 185 TSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY--SVYCSNGTTITLR 242
           T+ L      +   +   I  D+F++   +   ++  ++   DK    +       +TL 
Sbjct: 145 TA-LESC--GLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAKGKPYLTLE 201

Query: 243 EFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYFTLSEFVEMLYS 294
           +  +F+  +Q D   ++ +       QA   I  Y  +P +   E    ++  F   L  
Sbjct: 202 QLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQMSMEGFSRYLGG 259

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
           ++N I   +   ++ DMT+PLS Y+I+SSHNTYLT  Q +  SS+E Y + L  GCRC+E
Sbjct: 260 EENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLWGCRCVE 319

Query: 355 LDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-SLPQQ 411
           LD W G  P+  PFI HG T+TT++   DVL  I E AF TS YP+ILS E++  S  QQ
Sbjct: 320 LDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHVDSAKQQ 379

Query: 412 RRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
            +MA   + +FGD LL+ P+DK   +    LPSP D
Sbjct: 380 AKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 415


>M95678-1|AAA36453.1| 1181|Homo sapiens phospholipase C-beta-2
           protein.
          Length = 1181

 Score =  151 bits (366), Expect = 1e-35
 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%)

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
           V  L   +NS+       +  DMT+PL+HY+I+SSHNTYLT  QFS  SS E Y + L S
Sbjct: 292 VWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 351

Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
           GCRC+ELDCW G  PD  P I HG T+TT I F + +  I E AF TS YP+ILS E++ 
Sbjct: 352 GCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHV 411

Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443
             P QQ +MA   + +FGD+LL  P++    K    LPSP D
Sbjct: 412 DSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPED 453



 Score =  144 bits (350), Expect = 1e-33
 Identities = 100/270 (37%), Positives = 146/270 (54%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S L+ Y +    V+F     + + +V   +SSF E KA  L+S+  +  FV Y+  Q
Sbjct: 540  EEMSSLVNYIQPTKFVSFEFSAQKNRSYV---ISSFTELKAYDLLSKA-SVQFVDYNKRQ 595

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            +SRIYPKG R+DSSNY P  FWN G QMVALN+QT D PMQ NM  F+ NG  G++LK +
Sbjct: 596  MSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHE 655

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ +NP     I+  V   T+ + VI  + L +    T   +VEVE+ G   D  
Sbjct: 656  FMRRPDKQFNPFSVDRID-VVVATTLSITVISGQFLSERSVRT---YVEVELFGLPGDPK 711

Query: 1111 VKLVTK-TVSDNGLNPLW-NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             +  TK + S N +NP+W  +   FE +  PELA +R  V +E       F+G    P+ 
Sbjct: 712  RRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEG----NKFLGHRIIPIN 767

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L  GY  + L +  +  L +  L + L +
Sbjct: 768  ALNSGYHHLCLHSESNMPLTMPALFIFLEM 797


>AB209583-1|BAD92820.1|  901|Homo sapiens phospholipase C, beta 2
           variant protein.
          Length = 901

 Score =  151 bits (366), Expect = 1e-35
 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%)

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
           V  L   +NS+       +  DMT+PL+HY+I+SSHNTYLT  QFS  SS E Y + L S
Sbjct: 299 VWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 358

Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
           GCRC+ELDCW G  PD  P I HG T+TT I F + +  I E AF TS YP+ILS E++ 
Sbjct: 359 GCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHV 418

Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443
             P QQ +MA   + +FGD+LL  P++    K    LPSP D
Sbjct: 419 DSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPED 460



 Score =  144 bits (350), Expect = 1e-33
 Identities = 100/270 (37%), Positives = 146/270 (54%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S L+ Y +    V+F     + + +V   +SSF E KA  L+S+  +  FV Y+  Q
Sbjct: 551  EEMSSLVNYIQPTKFVSFEFSAQKNRSYV---ISSFTELKAYDLLSKA-SVQFVDYNKRQ 606

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            +SRIYPKG R+DSSNY P  FWN G QMVALN+QT D PMQ NM  F+ NG  G++LK +
Sbjct: 607  MSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHE 666

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ +NP     I+  V   T+ + VI  + L +    T   +VEVE+ G   D  
Sbjct: 667  FMRRPDKQFNPFSVDRID-VVVATTLSITVISGQFLSERSVRT---YVEVELFGLPGDPK 722

Query: 1111 VKLVTK-TVSDNGLNPLW-NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             +  TK + S N +NP+W  +   FE +  PELA +R  V +E       F+G    P+ 
Sbjct: 723  RRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEG----NKFLGHRIIPIN 778

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L  GY  + L +  +  L +  L + L +
Sbjct: 779  ALNSGYHHLCLHSESNMPLTMPALFIFLEM 808


>AK022543-1|BAB14090.1|  806|Homo sapiens protein ( Homo sapiens cDNA
            FLJ12481 fis, clone NT2RM1001072, weakly similar to
            1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE
            GAMMA ).
          Length = 806

 Score =  145 bits (351), Expect = 1e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 261  ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 319

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 320  YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 379

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 380  VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 437

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 438  VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 488


>BC019679-1|AAH19679.1|  716|Homo sapiens PLCH2 protein protein.
          Length = 716

 Score =  130 bits (314), Expect = 3e-29
 Identities = 76/188 (40%), Positives = 108/188 (57%), Gaps = 15/188 (7%)

Query: 1017 GSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTV 1076
            G QMVALNYQ+  + +Q+N  KF  NGGCG++LKP  M +  +NP  +  + G++K   +
Sbjct: 2    GCQMVALNYQSEGRMLQLNRAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKK-QL 60

Query: 1077 MLRVIGARHLCKT------GRG-TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWND 1129
            +LR+I  + L K        RG    PFVEVEIIG   D   +  T+ V DNG NP W +
Sbjct: 61   VLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCS-REQTRVVDDNGFNPTWEE 119

Query: 1130 ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELS 1189
               F V  PE+AL+RF+V D D  G  +FIGQ T     +  GYR V     + E +E +
Sbjct: 120  TLVFMVHMPEIALVRFLVWDHDPIGR-DFIGQRTLAFSSMMPGYRHV-----YLEGMEEA 173

Query: 1190 TLMVHLSI 1197
            ++ VH+++
Sbjct: 174  SIFVHVAV 181


>AL591042-2|CAI14458.1|  753|Homo sapiens vav 3 oncogene protein.
          Length = 753

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 624

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 625 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 679

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 680 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 738

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 739 G-RVGWFPSTYVEEDE 753



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 621

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 622 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 677

Query: 652 HEGK 655
             G+
Sbjct: 678 SAGQ 681


>AL591042-1|CAI14457.1|  847|Homo sapiens vav 3 oncogene protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>AL513206-2|CAH73196.1|  753|Homo sapiens vav 3 oncogene protein.
          Length = 753

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 624

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 625 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 679

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 680 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 738

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 739 G-RVGWFPSTYVEEDE 753



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 621

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 622 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 677

Query: 652 HEGK 655
             G+
Sbjct: 678 SAGQ 681


>AL513206-1|CAH73195.1|  847|Homo sapiens vav 3 oncogene protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>AL391235-1|CAH72458.1|  847|Homo sapiens vav 3 oncogene protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>AL353892-1|CAI21786.1|  847|Homo sapiens vav 3 oncogene protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>AF118887-1|AAD20349.1|  847|Homo sapiens VAV-3 protein protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>AF118886-1|AAD20348.1|  753|Homo sapiens VAV-3 protein beta isoform
           protein.
          Length = 753

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 624

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 625 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 679

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 680 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 738

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 739 G-RVGWFPSTYVEEDE 753



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 567 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 621

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 622 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 677

Query: 652 HEGK 655
             G+
Sbjct: 678 SAGQ 681


>AF067817-1|AAC79695.1|  847|Homo sapiens VAV-3 protein protein.
          Length = 847

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>BC013361-1|AAH13361.2|  790|Homo sapiens VAV1 protein protein.
          Length = 790

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 65/179 (36%), Positives = 88/179 (49%), Gaps = 12/179 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+     R  AE +L    +DG FLVR   K+   FAIS +   E+KH ++     LY I
Sbjct: 616 WYAGPMERAGAESILAN-RSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 674

Query: 717 GTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
              K F  L ELV +Y+ + L    K  +   + T++    EP+  T+   P       F
Sbjct: 675 TEKKAFRGLTELVEFYQQNSL----KDCFKSLDTTLQFPFKEPEKRTI-SRPAVGSTKYF 729

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYVLE 833
               T KA YD+ AR   ELS  +  II  ++K   +GWWRG+  G R  WFPANYV E
Sbjct: 730 G---TAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYG-RVGWFPANYVEE 784



 Score = 40.7 bits (91), Expect = 0.031
 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 15/120 (12%)

Query: 535 PQD-ELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           PQD  +H    W+ G +   R  AE +L   A+  DGTFLVR+ V    ++ +S     +
Sbjct: 608 PQDLSVHL---WYAGPM--ERAGAESIL---ANRSDGTFLVRQRVKDAAEFAISIKYNVE 659

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
           V H  IK+    G+  + + +   F  L  L+  Y+ + L+   +    TL+ P  +P K
Sbjct: 660 VKH--IKIMTAEGL--YRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEK 715


>AF030227-1|AAC25011.1|  845|Homo sapiens vav protein protein.
          Length = 845

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 65/179 (36%), Positives = 88/179 (49%), Gaps = 12/179 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+     R  AE +L    +DG FLVR   K+   FAIS +   E+KH ++     LY I
Sbjct: 671 WYAGPMERAGAESILAN-RSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 729

Query: 717 GTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
              K F  L ELV +Y+ + L    K  +   + T++    EP+  T+   P       F
Sbjct: 730 TEKKAFRGLTELVEFYQQNSL----KDCFKSLDTTLQFPFKEPEKRTI-SRPAVGSTKYF 784

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYVLE 833
               T KA YD+ AR   ELS  +  II  ++K   +GWWRG+  G R  WFPANYV E
Sbjct: 785 G---TAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYG-RVGWFPANYVEE 839



 Score = 40.7 bits (91), Expect = 0.031
 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 15/120 (12%)

Query: 535 PQD-ELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           PQD  +H    W+ G +   R  AE +L   A+  DGTFLVR+ V    ++ +S     +
Sbjct: 663 PQDLSVHL---WYAGPM--ERAGAESIL---ANRSDGTFLVRQRVKDAAEFAISIKYNVE 714

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
           V H  IK+    G+  + + +   F  L  L+  Y+ + L+   +    TL+ P  +P K
Sbjct: 715 VKH--IKIMTAEGL--YRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEK 770


>X83931-1|CAA58783.1|  539|Homo sapiens VAV protein.
          Length = 539

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 64/177 (36%), Positives = 87/177 (49%), Gaps = 12/177 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+     R  AE +L    +DG FLVR   K+   FAIS +   E+KH ++     LY I
Sbjct: 373 WYAGPMERAGAESILAN-RSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 431

Query: 717 GTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
              K F  L ELV +Y+ + L    K  +   + T++    EP+  T+   P       F
Sbjct: 432 TEKKAFRGLTELVEFYQQNSL----KDCFKSLDTTLQFPFKEPEKRTI-SRPAVGSTKYF 486

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
               T KA YD+ AR   ELS  +  II  ++K   +GWWRG+  G R  WFPANYV
Sbjct: 487 G---TAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYG-RVGWFPANYV 539



 Score = 40.7 bits (91), Expect = 0.031
 Identities = 35/120 (29%), Positives = 57/120 (47%), Gaps = 15/120 (12%)

Query: 535 PQD-ELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           PQD  +H    W+ G +   R  AE +L   A+  DGTFLVR+ V    ++ +S     +
Sbjct: 365 PQDLSVHL---WYAGPM--ERAGAESIL---ANRSDGTFLVRQRVKDAAEFAISIKYNVE 416

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
           V H  IK+    G+  + + +   F  L  L+  Y+ + L+   +    TL+ P  +P K
Sbjct: 417 VKH--IKIMTAEGL--YRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEK 472


>BX537442-1|CAD97684.1|  355|Homo sapiens hypothetical protein
            protein.
          Length = 355

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 48/102 (47%), Positives = 65/102 (63%), Gaps = 2/102 (1%)

Query: 1096 PFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGE 1155
            P+V +EI G   D   +  TKTV  N  NP++++  EF+V  PELA+IRFVV D+D  G+
Sbjct: 8    PYVCIEIHGIPADCSEQR-TKTVQQNSDNPIFDETFEFQVNLPELAMIRFVVLDDDYIGD 66

Query: 1156 PNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
              FIGQ T P  CL+ GYR VPL +   + +E  TL VH++I
Sbjct: 67   -EFIGQYTIPFECLQPGYRHVPLRSFVGDIMEHVTLFVHIAI 107


>X70766-1|CAA50045.1|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>L07527-1|AAA17022.1|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>L03535-1|AAA36611.1|  593|Homo sapiens phosphotyrosyl-protein
           phosphatase protein.
          Length = 593

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>D13540-1|BAA02740.2|  593|Homo sapiens protein-tyrosine phosphatase
           protein.
          Length = 593

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>BT007106-1|AAP35770.1|  460|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 11 (Noonan syndrome 1)
           protein.
          Length = 460

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>BC008692-1|AAH08692.1|  460|Homo sapiens PTPN11 protein protein.
          Length = 460

 Score = 89.0 bits (211), Expect = 9e-17
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>X16316-1|CAA34383.1|  797|Homo sapiens VAV protein.
          Length = 797

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 65/180 (36%), Positives = 88/180 (48%), Gaps = 13/180 (7%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH-CRVKQEGRLYT 715
           W+     R  AE +L    +DG FLVR   K+   FAIS +   E+KH  ++     LY 
Sbjct: 622 WYAGPMERAGAESILAN-RSDGTFLVRQRVKDAAEFAISIKYNVEVKHTVKIMTAEGLYR 680

Query: 716 IGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTS 774
           I   K F  L ELV +Y+ + L    K  +   + T++    EP+  T+   P       
Sbjct: 681 ITEKKAFRGLTELVEFYQQNSL----KDCFKSLDTTLQFPFKEPEKRTI-SRPAVGSTKY 735

Query: 775 FTSKVTVKALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYVLE 833
           F    T KA YD+ AR   ELS  +  II  ++K   +GWWRG+  G R  WFPANYV E
Sbjct: 736 FG---TAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYG-RVGWFPANYVEE 791



 Score = 40.7 bits (91), Expect = 0.031
 Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 14/120 (11%)

Query: 535 PQD-ELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           PQD  +H    W+ G +   R  AE +L   A+  DGTFLVR+ V    ++ +S     +
Sbjct: 614 PQDLSVHL---WYAGPM--ERAGAESIL---ANRSDGTFLVRQRVKDAAEFAISIKYNVE 665

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
           V H  +K+    G+  + + +   F  L  L+  Y+ + L+   +    TL+ P  +P K
Sbjct: 666 VKH-TVKIMTAEGL--YRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEK 722


>BX640754-1|CAE45861.1|  801|Homo sapiens hypothetical protein
           protein.
          Length = 801

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 607 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 665

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 666 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 723

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 724 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 775

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 776 QGWWKGETNG-RIGWFPSTYVEE 797



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 614 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 668

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 669 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 718


>BC132967-1|AAI32968.1|  839|Homo sapiens vav 2 oncogene protein.
          Length = 839

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 761

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 762 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 813

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 814 QGWWKGETNG-RIGWFPSTYVEE 835



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>BC132965-1|AAI32966.1|  839|Homo sapiens vav 2 oncogene protein.
          Length = 839

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 761

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 762 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 813

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 814 QGWWKGETNG-RIGWFPSTYVEE 835



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>BC128448-1|AAI28449.1|  474|Homo sapiens VAV2 protein protein.
          Length = 474

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 280 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 338

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 339 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 396

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 397 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 448

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 449 QGWWKGETNG-RIGWFPSTYVEE 470



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 287 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 341

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 342 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 391


>BC033187-1|AAH33187.1|  369|Homo sapiens VAV2 protein protein.
          Length = 369

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 175 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 233

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 234 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 291

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 292 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 343

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 344 QGWWKGETNG-RIGWFPSTYVEE 365



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 182 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 236

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 237 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 286


>AL590710-5|CAI12280.1|  839|Homo sapiens vav 2 oncogene protein.
          Length = 839

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 761

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 762 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 813

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 814 QGWWKGETNG-RIGWFPSTYVEE 835



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>AL445931-1|CAI13724.1|  839|Homo sapiens vav 2 oncogene protein.
          Length = 839

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 761

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 762 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 813

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 814 QGWWKGETNG-RIGWFPSTYVEE 835



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>AL357934-1|CAI15782.1|  839|Homo sapiens vav 2 oncogene protein.
          Length = 839

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 62/203 (30%), Positives = 95/203 (46%), Gaps = 24/203 (11%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPISEETVR 752
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP       
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSR--E 761

Query: 753 RLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK--PD 810
           R  S     +   TP  +         T  A Y++ AR   ELS  +  ++    +   D
Sbjct: 762 RSASRASSRSPVFTPRVIG--------TAVARYNFAARDMRELSLREGDVVRIYSRIGGD 813

Query: 811 EGWWRGDYGGKRHHWFPANYVLE 833
           +GWW+G+  G R  WFP+ YV E
Sbjct: 814 QGWWKGETNG-RIGWFPSTYVEE 835



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>X62852-1|CAA44664.1|  160|Homo sapiens ash protein protein.
          Length = 160

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 3   WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 62

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 63  LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 103

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 104 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 156



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 3   WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 56

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 57  -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 99


>M96995-1|AAA58448.1|  217|Homo sapiens epidermal growth factor
           receptor-binding protein GRB2 protein.
          Length = 217

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>CR541942-1|CAG46740.1|  217|Homo sapiens GRB2 protein.
          Length = 217

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>BC000631-1|AAH00631.1|  217|Homo sapiens growth factor
           receptor-bound protein 2 protein.
          Length = 217

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>AF498925-1|AAM21073.1|  217|Homo sapiens growth factor
           receptor-bound protein 2 protein.
          Length = 217

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>AF063618-1|AAC72075.1|  217|Homo sapiens growth factor
           receptor-bound protein 2 protein.
          Length = 217

 Score = 83.4 bits (197), Expect = 4e-15
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>U52518-1|AAC50541.1|  217|Homo sapiens Grb2-related adaptor protein
           protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>CR541966-1|CAG46764.1|  217|Homo sapiens GRAP protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>CR541941-1|CAG46739.1|  217|Homo sapiens GRAP protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>CR450363-1|CAG29359.1|  217|Homo sapiens GRB2 protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 55/179 (30%), Positives = 87/179 (48%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D     WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSGPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 0.16
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>BT019981-1|AAV38784.1|  217|Homo sapiens GRB2-related adaptor
           protein protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>BC063035-1|AAH63035.1|  217|Homo sapiens GRB2-related adaptor
           protein protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>BC035856-1|AAH35856.1|  217|Homo sapiens GRB2-related adaptor
           protein protein.
          Length = 217

 Score = 80.6 bits (190), Expect = 3e-14
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>S76992-1|AAB34377.1|  878|Homo sapiens VAV2 protein.
          Length = 878

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766


>AL590710-7|CAI12279.1|  878|Homo sapiens vav 2 oncogene protein.
          Length = 878

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766


>AL590710-6|CAI12278.1|  868|Homo sapiens vav 2 oncogene protein.
          Length = 868

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 763

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 764 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 823

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 824 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 864



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>AL445931-3|CAI13723.1|  868|Homo sapiens vav 2 oncogene protein.
          Length = 868

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 763

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 764 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 823

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 824 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 864



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>AL445931-2|CAI13722.1|  878|Homo sapiens vav 2 oncogene protein.
          Length = 878

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766


>AL357934-3|CAI15781.1|  868|Homo sapiens vav 2 oncogene protein.
          Length = 868

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 645 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 703

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 704 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 763

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 764 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 823

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 824 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 864



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 652 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 706

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 707 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 756


>AL357934-2|CAI15783.1|  878|Homo sapiens vav 2 oncogene protein.
          Length = 878

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766


>AK122591-1|BAC56932.1|  600|Homo sapiens FLJ00417 protein protein.
          Length = 600

 Score = 79.8 bits (188), Expect = 5e-14
 Identities = 44/106 (41%), Positives = 61/106 (57%), Gaps = 7/106 (6%)

Query: 1092 GTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDED 1151
            G+  PFVEVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D
Sbjct: 172  GSFDPFVEVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHD 230

Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
              G  +FIGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 231  PIGR-DFIGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 270


>AY512961-1|AAS82574.1|  272|Homo sapiens truncated phospholipase C
           delta-4 protein.
          Length = 272

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 50/188 (26%), Positives = 95/188 (50%), Gaps = 12/188 (6%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECE 127
           +  I DV+ +R G  S+      EE   L   + FTI ++G    L     +A + +E +
Sbjct: 60  SFSISDVETIRNGHDSELLRSLAEE---LPLEQGFTIVFHGRRSNL---DLMANSVEEAQ 113

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFY-SIENSHEKITLKEVKAFLPKINCKISTS 186
            W++G+  L+    S  +  ++++WL   F    +N   K++ +EV+  L  +N ++   
Sbjct: 114 IWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQE 173

Query: 187 KLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQN 246
               +FQ  DT + G +  ++F   Y K +     VQ++F+ +S   ++G  +TL EF +
Sbjct: 174 YAFSLFQAADTSQSGTLEGEEFVQFY-KALTKRAEVQELFESFS---ADGQKLTLLEFLD 229

Query: 247 FLRDEQHD 254
           FL++EQ +
Sbjct: 230 FLQEEQKE 237


>X62055-1|CAA43982.1|  597|Homo sapiens protein-tyrosine
           phosphatase 1C protein.
          Length = 597

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 6   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 58

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 59  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 115

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 116 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 175

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 176 GRYTVGGLETFDSLTDLVEHFK 197



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 109 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 165 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 197


>U47924-18|AAB51323.1|  595|Homo sapiens protein tyrosine
           phosphatase 1C protein.
          Length = 595

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>M74903-1|AAA35963.1|  595|Homo sapiens hematopoietic cell
           phophatase protein.
          Length = 595

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>BT007390-1|AAP36054.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 6   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 58

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 59  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 115

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 116 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 175

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 176 GRYTVGGLETFDSLTDLVEHFK 197



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 109 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 165 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 197


>BC007667-1|AAH07667.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 6   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 58

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 59  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 115

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 116 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 175

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 176 GRYTVGGLETFDSLTDLVEHFK 197



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 109 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 165 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 197


>BC002523-1|AAH02523.1|  597|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 protein.
          Length = 597

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 6   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 58

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 59  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 115

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 116 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 175

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 176 GRYTVGGLETFDSLTDLVEHFK 197



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 109 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 165 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 197


>AK223629-1|BAD97349.1|  595|Homo sapiens protein tyrosine
           phosphatase, non-receptor type 6 isoform 1 variant
           protein.
          Length = 595

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>AB079851-2|BAC81775.1|  595|Homo sapiens protein tyrosine
           phosphatase SHP-1 protein.
          Length = 595

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>AB079851-1|BAC81774.1|  597|Homo sapiens protein tyrosine
           phosphatase SHP-1 protein.
          Length = 597

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 6   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 58

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 59  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 115

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 116 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 175

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 176 GRYTVGGLETFDSLTDLVEHFK 197



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 109 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 164

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 165 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 197


>M77273-1|AAA36610.1|  595|Homo sapiens tyrosine phosphatase
           protein.
          Length = 595

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 64/202 (31%), Positives = 96/202 (47%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHPLRSQE---FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y       Q+    +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVVQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>AF178946-1|AAD53317.1|  624|Homo sapiens 70 kDa SHP-1L protein
           protein.
          Length = 624

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 64/202 (31%), Positives = 96/202 (47%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHPLRSQE---FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y       Q+    +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVVQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.054
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>BC007195-1|AAH07195.1|  380|Homo sapiens NCK adaptor protein 2
           protein.
          Length = 380

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 29/84 (34%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QAE  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 282 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 341

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 342 YCIGQRRFHTMDELVEHYKKAPIF 365



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K + +T ++K  +GWWRG Y G +  WFP+NYVLE
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 167



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +AE  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 285 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 337

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 338 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 368



 Score = 39.5 bits (88), Expect = 0.071
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      R  + P+NYV
Sbjct: 2   TEEVIVIAKWDYTAQQDQELDIKKNERLWLLD-DSKTWWRVRNAANRTGYVPSNYV 56


>BC000103-1|AAH00103.1|  380|Homo sapiens NCK adaptor protein 2
           protein.
          Length = 380

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 29/84 (34%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QAE  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 282 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 341

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 342 YCIGQRRFHTMDELVEHYKKAPIF 365



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K + +T ++K  +GWWRG Y G +  WFP+NYVLE
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 167



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +AE  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 285 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 337

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 338 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 368



 Score = 39.5 bits (88), Expect = 0.071
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      R  + P+NYV
Sbjct: 2   TEEVIVIAKWDYTAQQDQELDIKKNERLWLLD-DSKTWWRVRNAANRTGYVPSNYV 56


>AF047487-1|AAC80284.1|  380|Homo sapiens Nck-2 protein.
          Length = 380

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 29/84 (34%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QAE  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 282 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 341

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 342 YCIGQRRFHTMDELVEHYKKAPIF 365



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 1/76 (1%)

Query: 758 PDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGD 817
           P  +  Y   G      +   +     + Y A ++DELS  K + +T ++K  +GWWRG 
Sbjct: 93  PSTDAEYAANGSGADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGS 152

Query: 818 YGGKRHHWFPANYVLE 833
           Y G +  WFP+NYVLE
Sbjct: 153 YNG-QIGWFPSNYVLE 167



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +AE  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 285 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 337

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 338 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 368



 Score = 39.5 bits (88), Expect = 0.071
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      R  + P+NYV
Sbjct: 2   TEEVIVIAKWDYTAQQDQELDIKKNERLWLLD-DSKTWWRVRNAANRTGYVPSNYV 56


>AC009505-1|AAY24332.1|  304|Homo sapiens unknown protein.
          Length = 304

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 29/84 (34%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QAE  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 206 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 265

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 266 YCIGQRRFHTMDELVEHYKKAPIF 289



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K + +T ++K  +GWWRG Y G +  WFP+NYVLE
Sbjct: 44  FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 91



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +AE  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 209 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 261

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 262 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 292


>X17576-1|CAA35599.1|  377|Homo sapiens protein ( Human melanoma
           mRNA for nck protein, showing homology to src. ).
          Length = 377

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%)

Query: 651 KHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           K  G  W++   TR QAE  L +   +G FL+R SE     F++S + + + KH +V+ +
Sbjct: 276 KFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLK 335

Query: 711 GRLYTIGTVKFESLIELVSYYENHPLY 737
             +Y IG  KF ++ ELV +Y+  P++
Sbjct: 336 ETVYCIGQRKFSTMEELVEHYKKAPIF 362



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 6/121 (4%)

Query: 751 VRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKAL--YDYRARQDDELSFCKHAIITNVDK 808
           V+R  S PD  +      ++DP      + + A   ++Y A ++DELS  K   +  ++K
Sbjct: 80  VKRKPSVPDSASP-ADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEK 138

Query: 809 PDEGWWRGDYGGKRHHWFPANYVLEI-EVPHTPDVTSGLENESAALGSLQKG-VLDVLGA 866
             +GWWRG Y G +  WFP+NYV E  + P    V S  E  +A + +L  G VL V+ A
Sbjct: 139 CSDGWWRGSYNG-QVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQA 197

Query: 867 I 867
           +
Sbjct: 198 L 198



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++GK+   R +AE  L    H GD  FL+R+S +   D+ +S   QGK  H +++LK+ 
Sbjct: 282 WYYGKVT--RHQAEMALNERGHEGD--FLIRDSESSPNDFSVSLKAQGKNKHFKVQLKE- 336

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
                 Y I    F ++  L+ HY+  P+ + E
Sbjct: 337 ----TVYCIGQRKFSTMEELVEHYKKAPIFTSE 365



 Score = 37.5 bits (83), Expect = 0.29
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 5/69 (7%)

Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIEVPH 838
           V+ALY + +  D+EL+F K  ++  ++KP  D  WW+           P NYV  ++  +
Sbjct: 195 VQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQ--N 252

Query: 839 TPDVTSGLE 847
            P +TSGLE
Sbjct: 253 NP-LTSGLE 260



 Score = 34.3 bits (75), Expect = 2.7
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +V V A +DY A+Q+ EL   K+  +  +D   + WWR      +  + P+NYV
Sbjct: 4   EVVVVAKFDYVAQQEQELDIKKNERLWLLDD-SKSWWRVRNSMNKTGFVPSNYV 56


>M23612-1|AAA35865.1|  870|Homo sapiens GTPase-activating protein
           protein.
          Length = 870

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRL 713
           K W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      
Sbjct: 2   KGWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGD 61

Query: 714 YTIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
           Y IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 62  YYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 96



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 165 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 224

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 225 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 284

Query: 766 T 766
           T
Sbjct: 285 T 285



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 165 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 220

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++ +
Sbjct: 221 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 271



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 4   WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 55

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 56  -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 100


>BC054891-1|AAH54891.1|  313|Homo sapiens RASA1 protein protein.
          Length = 313

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRL 713
           K W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      
Sbjct: 2   KGWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGD 61

Query: 714 YTIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
           Y IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 62  YYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 96



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 165 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 224

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 225 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 284

Query: 766 T 766
           T
Sbjct: 285 T 285



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 40/161 (24%), Positives = 76/161 (47%), Gaps = 20/161 (12%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 165 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 220

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKH--- 652
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++    
Sbjct: 221 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQVL 273

Query: 653 ----EGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQ 689
               +GKE ++    R + ++   K      +L++  +K++
Sbjct: 274 NDTVDGKEIYNT--IRRKTKDAFYKNIVKKGYLLKKKKKKK 312



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 4   WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 55

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 56  -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 100


>BC020761-1|AAH20761.1|  317|Homo sapiens Unknown (protein for
           IMAGE:4733187) protein.
          Length = 317

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 36/95 (37%), Positives = 54/95 (56%), Gaps = 2/95 (2%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRL 713
           K W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      
Sbjct: 2   KGWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGD 61

Query: 714 YTIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
           Y IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 62  YYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 96



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 165 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 224

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 225 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 284

Query: 766 T 766
           T
Sbjct: 285 T 285



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 40/161 (24%), Positives = 77/161 (47%), Gaps = 20/161 (12%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 165 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 220

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKH--- 652
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++    
Sbjct: 221 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQVL 273

Query: 653 ----EGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQ 689
               +GKE ++    R + ++   K      +L++ ++K++
Sbjct: 274 NDTVDGKEIYNT--IRRKTKDAFYKNIVKKGYLLKEAKKKK 312



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 4   WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 55

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 56  -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 100


>BC006403-1|AAH06403.1|  377|Homo sapiens NCK adaptor protein 1
           protein.
          Length = 377

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%)

Query: 651 KHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           K  G  W++   TR QAE  L +   +G FL+R SE     F++S + + + KH +V+ +
Sbjct: 276 KFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLK 335

Query: 711 GRLYTIGTVKFESLIELVSYYENHPLY 737
             +Y IG  KF ++ ELV +Y+  P++
Sbjct: 336 ETVYCIGQRKFSTMEELVEHYKKAPIF 362



 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 41/121 (33%), Positives = 63/121 (52%), Gaps = 6/121 (4%)

Query: 751 VRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKAL--YDYRARQDDELSFCKHAIITNVDK 808
           V+R  S PD  +      ++DP      + + A   ++Y A ++DELS  K   +  ++K
Sbjct: 80  VKRKPSVPDSASP-ADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKGTKVIVMEK 138

Query: 809 PDEGWWRGDYGGKRHHWFPANYVLEI-EVPHTPDVTSGLENESAALGSLQKG-VLDVLGA 866
             +GWWRG Y G +  WFP+NYV E  + P    V S  E  +A + +L  G VL V+ A
Sbjct: 139 CSDGWWRGSYNG-QVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVVQA 197

Query: 867 I 867
           +
Sbjct: 198 L 198



 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++GK+   R +AE  L    H GD  FL+R+S +   D+ +S   QGK  H +++LK+ 
Sbjct: 282 WYYGKVT--RHQAEMALNERGHEGD--FLIRDSESSPNDFSVSLKAQGKNKHFKVQLKE- 336

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
                 Y I    F ++  L+ HY+  P+ + E
Sbjct: 337 ----TVYCIGQRKFSTMEELVEHYKKAPIFTSE 365



 Score = 37.5 bits (83), Expect = 0.29
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 5/69 (7%)

Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIEVPH 838
           V+ALY + +  D+EL+F K  ++  ++KP  D  WW+           P NYV  ++  +
Sbjct: 195 VQALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQ--N 252

Query: 839 TPDVTSGLE 847
            P +TSGLE
Sbjct: 253 NP-LTSGLE 260



 Score = 34.3 bits (75), Expect = 2.7
 Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +V V A +DY A+Q+ EL   K+  +  +D   + WWR      +  + P+NYV
Sbjct: 4   EVVVVAKFDYVAQQEQELDIKKNERLWLLDD-SKSWWRVRNSMNKTGFVPSNYV 56


>M23379-1|AAA52517.1| 1047|Homo sapiens GTPase-activating protein
           protein.
          Length = 1047

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRLY 714
           +W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      Y
Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239

Query: 715 TIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
            IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 240 YIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 273



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 342 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 401

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 402 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 461

Query: 766 T 766
           T
Sbjct: 462 T 462



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 342 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 397

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++ +
Sbjct: 398 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 448



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 181 WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 232

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 233 -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 277


>BC033015-1|AAH33015.1| 1047|Homo sapiens RAS p21 protein activator
           (GTPase activating protein) 1 protein.
          Length = 1047

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRLY 714
           +W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      Y
Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239

Query: 715 TIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
            IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 240 YIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 273



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 342 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 401

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 402 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 461

Query: 766 T 766
           T
Sbjct: 462 T 462



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 342 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 397

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++ +
Sbjct: 398 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 448



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 181 WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 232

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 233 -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 277


>AB209106-1|BAD92343.1|  871|Homo sapiens RAS p21 protein activator
           1 isoform 1 variant protein.
          Length = 871

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRLY 714
           +W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      Y
Sbjct: 213 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 272

Query: 715 TIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
            IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 273 YIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 306



 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 375 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 434

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 435 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 494

Query: 766 T 766
           T
Sbjct: 495 T 495



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 375 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 430

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++ +
Sbjct: 431 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 481



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 214 WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 265

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 266 -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 310


>AF043119-1|AAC04831.1|  381|Homo sapiens SH2/SH3 adaptor protein
           NCK-beta protein.
          Length = 381

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 28/84 (33%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QA+  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 283 GREWYYGNVTRHQAQCALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 342

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 343 YCIGQRRFHTMDELVEHYKKAPIF 366



 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K + +T ++K  +GWWRG Y G +  WFP+NYVLE
Sbjct: 121 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 168



 Score = 41.5 bits (93), Expect = 0.018
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +A+  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 286 WYYGNVT--RHQAQCALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 338

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 339 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 369



 Score = 35.5 bits (78), Expect = 1.2
 Identities = 20/56 (35%), Positives = 27/56 (48%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K      +    + WWR      R  + P+NYV
Sbjct: 2   TEEVIVIAKWDYTAQQDQELDIKKVNERLWLLDDSKTWWRVRNAANRTGYVPSNYV 57


>U15528-2|AAA82880.1|  595|Homo sapiens protein tyrosine phosphatase
           1C protein.
          Length = 595

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 63/202 (31%), Positives = 97/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF   L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFLRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFELSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 38.7 bits (86), Expect = 0.12
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFELSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>BC128208-1|AAI28209.1|  368|Homo sapiens PLCH2 protein protein.
          Length = 368

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 15/221 (6%)

Query: 102 CFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEF 157
           CF+IY+G+  +      V+ + +    WV G+ YL+A    E   A      ++WL++ F
Sbjct: 6   CFSIYHGSHRE--SLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTF 63

Query: 158 YSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKL 215
              + N    +++ EV   L K+N  +   +++ +F++ DT + +G +GF++F   Y+ +
Sbjct: 64  DEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM 123

Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275
               +  +D++     Y ++   +     Q FL+ EQ   +    +++ Q I +      
Sbjct: 124 ----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCP 177

Query: 276 RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT-RPL 315
            +  +    +  F     S    I++ ++  V QDMT RPL
Sbjct: 178 ENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQRPL 218


>U34379-1|AAB60412.1|  527|Homo sapiens tyrosine kinase protein.
          Length = 527

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 9/99 (9%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISF------RTEKEIKHCRVKQ 709
           EW+H + TR QAE LLR+ + +GAF+VR S +  GS+ IS        TE  IKH ++K+
Sbjct: 149 EWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAAIKHYQIKK 207

Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI 746
              G+ Y      F+S+ EL+ Y++++      +L YP+
Sbjct: 208 NDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPV 246



 Score = 33.5 bits (73), Expect = 4.7
 Identities = 17/59 (28%), Positives = 29/59 (49%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836
           K+ VKALYD+  R+   L+  +      ++K +  WW+           P+NYV E ++
Sbjct: 84  KIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKI 142


>L27071-1|AAA74557.1|  527|Homo sapiens tyrosine kinase protein.
          Length = 527

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 9/99 (9%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISF------RTEKEIKHCRVKQ 709
           EW+H + TR QAE LLR+ + +GAF+VR S +  GS+ IS        TE  IKH ++K+
Sbjct: 149 EWYHRNITRNQAEHLLRQESKEGAFIVRDS-RHLGSYTISVFMGARRSTEAAIKHYQIKK 207

Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI 746
              G+ Y      F+S+ EL+ Y++++      +L YP+
Sbjct: 208 NDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPV 246



 Score = 33.5 bits (73), Expect = 4.7
 Identities = 17/59 (28%), Positives = 29/59 (49%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836
           K+ VKALYD+  R+   L+  +      ++K +  WW+           P+NYV E ++
Sbjct: 84  KIQVKALYDFLPREPCNLALRRAEEYLILEKYNPHWWKARDRLGNEGLIPSNYVTENKI 142


>BC012924-1|AAH12924.1|  280|Homo sapiens DAPP1 protein protein.
          Length = 280

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 32/102 (31%), Positives = 51/102 (50%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H + TR  AE LL     DG++L+R S +  G +++S R +  +KH  V+  G  +  
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758
           G  +F SL + V ++ N PL         + +    R V EP
Sbjct: 95  GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R  AE LL ++    DG++L+R+S    G Y LS   +  V H  ++    
Sbjct: 35  WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648
               KF   +   F SL + + H+ + PL   E   L+ LK P P+
Sbjct: 91  S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131


>AF186022-1|AAF14578.1|  280|Homo sapiens B lymphocyte adapter
           protein BAM32 protein.
          Length = 280

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 32/102 (31%), Positives = 51/102 (50%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H + TR  AE LL     DG++L+R S +  G +++S R +  +KH  V+  G  +  
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758
           G  +F SL + V ++ N PL         + +    R V EP
Sbjct: 95  GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R  AE LL ++    DG++L+R+S    G Y LS   +  V H  ++    
Sbjct: 35  WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648
               KF   +   F SL + + H+ + PL   E   L+ LK P P+
Sbjct: 91  S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131


>AF178987-1|AAF44351.1|  280|Homo sapiens protein-tyrosine
           phosphatase D protein.
          Length = 280

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 32/102 (31%), Positives = 51/102 (50%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H + TR  AE LL     DG++L+R S +  G +++S R +  +KH  V+  G  +  
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758
           G  +F SL + V ++ N PL         + +    R V EP
Sbjct: 95  GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R  AE LL ++    DG++L+R+S    G Y LS   +  V H  ++    
Sbjct: 35  WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648
               KF   +   F SL + + H+ + PL   E   L+ LK P P+
Sbjct: 91  S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131


>AF163254-1|AAD49697.1|  280|Homo sapiens adaptor protein DAPP1
           protein.
          Length = 280

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 32/102 (31%), Positives = 51/102 (50%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H + TR  AE LL     DG++L+R S +  G +++S R +  +KH  V+  G  +  
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758
           G  +F SL + V ++ N PL         + +    R V EP
Sbjct: 95  GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136



 Score = 42.3 bits (95), Expect = 0.010
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R  AE LL ++    DG++L+R+S    G Y LS   +  V H  ++    
Sbjct: 35  WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648
               KF   +   F SL + + H+ + PL   E   L+ LK P P+
Sbjct: 91  S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131


>BC008799-1|AAH08799.1|  513|Homo sapiens cortactin protein.
          Length = 513

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 30/53 (56%), Positives = 37/53 (69%), Gaps = 1/53 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +T  ALYDY+A  DDE+SF    IITN++  D+GWWRG   G R+  FPANYV
Sbjct: 458 ITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG-RYGLFPANYV 509


>AK222613-1|BAD96333.1|  550|Homo sapiens cortactin isoform a
           variant protein.
          Length = 550

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 30/53 (56%), Positives = 37/53 (69%), Gaps = 1/53 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +T  ALYDY+A  DDE+SF    IITN++  D+GWWRG   G R+  FPANYV
Sbjct: 495 ITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG-RYGLFPANYV 546


>AK027488-1|BAB55148.1|  426|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14582 fis, clone NT2RM4001411, highly similar to
           Mus musculus Pro-rich, PH, SH2 domain-containing
           signaling ).
          Length = 426

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 282 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 339

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKEWFHAH 661
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G+E   +H
Sbjct: 340 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSH 395



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 279 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 338

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 339 EGQC-RVQHLWFQSIFDMLEHFRVHPI 364


>AF227968-1|AAF73913.1|  671|Homo sapiens SH2-B beta signaling
           protein protein.
          Length = 671

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 527 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKEWFHAH 661
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G+E   +H
Sbjct: 585 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSH 640



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 524 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 583

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 584 EGQC-RVQHLWFQSIFDMLEHFRVHPI 609


>AB037720-1|BAA92537.1|  730|Homo sapiens KIAA1299 protein protein.
          Length = 730

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 9/120 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 586 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 643

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKEWFHAH 661
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G+E   +H
Sbjct: 644 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSH 699



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 583 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 642

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 643 EGQC-RVQHLWFQSIFDMLEHFRVHPI 668


>BC010704-1|AAH10704.1|  426|Homo sapiens SH2B1 protein protein.
          Length = 426

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 39/120 (32%), Positives = 62/120 (51%), Gaps = 9/120 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L         G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 282 WFHGMLS--RLKAAQLALTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 339

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKEWFHAH 661
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G+E   +H
Sbjct: 340 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSH 395



 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 26/87 (29%), Positives = 49/87 (56%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L     T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 279 GYPWFHGMLSRLKAAQLALTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 338

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 339 EGQC-RVQHLWFQSIFDMLEHFRVHPI 364


>M98343-1|AAA58455.1|  550|Homo sapiens amplaxin protein.
          Length = 550

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 30/52 (57%), Positives = 36/52 (69%), Gaps = 1/52 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T  ALYDY+A  DDE+SF    IITN++  D+GWWRG   G R+  FPANYV
Sbjct: 496 TAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG-RYGLFPANYV 546


>DQ402497-1|ABD62889.1|  478|Homo sapiens nostrin protein.
          Length = 478

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 364 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 422

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 423 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 467


>BC093072-1|AAH93072.1|  506|Homo sapiens nitric oxide synthase
           trafficker protein.
          Length = 506

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 392 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 450

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 451 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 495


>BC014189-1|AAH14189.1|  428|Homo sapiens nitric oxide synthase
           trafficker protein.
          Length = 428

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 314 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 372

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 373 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 417


>AK002203-1|BAE46614.1|  506|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11341 fis, clone PLACE1010786, highly  similar
           to Mus musculus nitric oxide synthase trafficker. ).
          Length = 506

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 392 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 450

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 451 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 495


>AJ532842-1|CAD58724.1|  506|Homo sapiens NOSTRIN protein protein.
          Length = 506

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 392 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 450

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 451 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 495


>Z82206-3|CAI42713.1|  330|Homo sapiens GRB2-related adaptor protein
           2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>Y18051-1|CAA77021.1|  330|Homo sapiens GADS protein protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>CR541849-1|CAG46647.1|  330|Homo sapiens GRAP2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>CR536524-1|CAG38761.1|  330|Homo sapiens GRAP2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>CR456498-1|CAG30384.1|  330|Homo sapiens GRAP2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>BC026002-1|AAH26002.1|  330|Homo sapiens GRAP2 protein protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>BC025692-1|AAH25692.1|  330|Homo sapiens GRB2-related adaptor
           protein 2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AY069959-1|AAL58573.1|  330|Homo sapiens Mona protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AL049924-1|CAB43208.1|  540|Homo sapiens hypothetical protein
           protein.
          Length = 540

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 9/115 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 384 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 441

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKE 656
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G++
Sbjct: 442 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGEQ 492



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 381 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 440

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 441 EGQC-RVQHLWFQSIFDMLEHFRVHPI 466


>AJ011736-1|CAA09757.1|  330|Homo sapiens growth factor receptor
           binding protein (GRBLG) protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF236120-1|AAF60320.1|  330|Homo sapiens adapter protein GRID
           protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF236119-1|AAF60319.1|  330|Homo sapiens adapter protein GRID
           protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 21/50 (42%), Positives = 29/50 (58%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K   +FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GFFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF227969-1|AAF73914.1|  683|Homo sapiens SH2-B gamma signaling
           protein protein.
          Length = 683

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 37/115 (32%), Positives = 61/115 (53%), Gaps = 9/115 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 527 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQ---EFLITLKEPVPQPNKHEGKE 656
            G  +   +  + F S+++++ H+R HP+  +      + L   VP   + +G++
Sbjct: 585 -GQCR---VQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGEQ 635



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 524 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 583

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 584 EGQC-RVQHLWFQSIFDMLEHFRVHPI 609


>AF129476-1|AAD41782.1|  330|Homo sapiens hematopoietic
           cell-associated adaptor protein GrpL protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF121002-1|AAF31758.1|  330|Homo sapiens SH3-SH2-SH3 adaptor
           protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF102694-1|AAD04926.1|  330|Homo sapiens Grb2-related adaptor
           protein 2 protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF090456-1|AAD13027.1|  330|Homo sapiens Grb-2-like protein
           protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF042380-1|AAC69273.1|  330|Homo sapiens Grf40 adaptor protein
           protein.
          Length = 330

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.013
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>AF227967-1|AAF73912.1|  756|Homo sapiens SH2-B alpha signaling
           protein protein.
          Length = 756

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 33/89 (37%), Positives = 51/89 (57%), Gaps = 6/89 (6%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 527 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
            G  +   +  + F S+++++ H+R HP+
Sbjct: 585 -GQCR---VQHLWFQSIFDMLEHFRVHPI 609



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 524 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 583

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 584 EGQC-RVQHLWFQSIFDMLEHFRVHPI 609


>BC031687-1|AAH31687.1|  430|Homo sapiens drebrin-like protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>BC011677-1|AAH11677.1|  431|Homo sapiens drebrin-like protein.
          Length = 431

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 378 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 431


>AK027367-1|BAB55065.1|  439|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14461 fis, clone MAMMA1000173, highly similar to
           Homo sapiens src homology 3 domain-containing protein
           HIP-55 ).
          Length = 439

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 386 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 439


>AF250287-1|AAF81273.1|  430|Homo sapiens cervical SH3P7 protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>AF218020-1|AAG17262.2|  430|Homo sapiens unknown protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>AF197060-1|AAF13701.1|  430|Homo sapiens src homology 3
           domain-containing protein HIP-55 protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>AF151364-1|AAG13120.1|  430|Homo sapiens mucin-associated protein
           protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>AF077353-1|AAF80228.1|  430|Homo sapiens drebrin F protein.
          Length = 430

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>AB209486-1|BAD92723.1|  358|Homo sapiens Drebrin-like protein
           variant protein.
          Length = 358

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 305 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 358


>X59656-1|CAA42199.1|  303|Homo sapiens CRKL protein.
          Length = 303

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 13/196 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715
           W+    +R +A+  L+     G FLVR S    G + +S      + H  +     R + 
Sbjct: 14  WYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           IG  +F+ L  L+ +Y+ H L     +      E   R  S P  +     P    PT+ 
Sbjct: 73  IGDQEFDHLPALLEFYKIHYLDTTTLI------EPAPRYPSPPMGSV--SAPNL--PTAE 122

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
            +   V+ LYD+     ++L F K  I+  ++KP+E WW       R    P  YV ++ 
Sbjct: 123 DNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL- 181

Query: 836 VPHTPDVTSGLENESA 851
           V  +P    G  N ++
Sbjct: 182 VRSSPHGKHGNRNSNS 197



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 13/104 (12%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G ++  RQEA+  L+   H   G FLVR+S T  GDY LS     +V+H  I     
Sbjct: 14  WYMGPVS--RQEAQTRLQGQRH---GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQ 648
           R   +F + D   FD L  L+  Y+ H L +     TL EP P+
Sbjct: 69  R---RFKIGDQE-FDHLPALLEFYKIHYLDT----TTLIEPAPR 104


>CR456423-1|CAG30309.1|  303|Homo sapiens CRKL protein.
          Length = 303

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 13/196 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715
           W+    +R +A+  L+     G FLVR S    G + +S      + H  +     R + 
Sbjct: 14  WYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           IG  +F+ L  L+ +Y+ H L     +      E   R  S P  +     P    PT+ 
Sbjct: 73  IGDQEFDHLPALLEFYKIHYLDTTTLI------EPAPRYPSPPMGSV--SAPNL--PTAE 122

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
            +   V+ LYD+     ++L F K  I+  ++KP+E WW       R    P  YV ++ 
Sbjct: 123 DNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL- 181

Query: 836 VPHTPDVTSGLENESA 851
           V  +P    G  N ++
Sbjct: 182 VRSSPHGKHGNRNSNS 197



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 13/104 (12%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G ++  RQEA+  L+   H   G FLVR+S T  GDY LS     +V+H  I     
Sbjct: 14  WYMGPVS--RQEAQTRLQGQRH---GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQ 648
           R   +F + D   FD L  L+  Y+ H L +     TL EP P+
Sbjct: 69  R---RFKIGDQE-FDHLPALLEFYKIHYLDT----TTLIEPAPR 104


>BC043500-1|AAH43500.1|  303|Homo sapiens v-crk sarcoma virus CT10
           oncogene homolog (avian)-like protein.
          Length = 303

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 13/196 (6%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715
           W+    +R +A+  L+     G FLVR S    G + +S      + H  +     R + 
Sbjct: 14  WYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           IG  +F+ L  L+ +Y+ H L     +      E   R  S P  +     P    PT+ 
Sbjct: 73  IGDQEFDHLPALLEFYKIHYLDTTTLI------EPAPRYPSPPMGSV--SAPNL--PTAE 122

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
            +   V+ LYD+     ++L F K  I+  ++KP+E WW       R    P  YV ++ 
Sbjct: 123 DNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL- 181

Query: 836 VPHTPDVTSGLENESA 851
           V  +P    G  N ++
Sbjct: 182 VRSSPHGKHGNRNSNS 197



 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 38/104 (36%), Positives = 52/104 (50%), Gaps = 13/104 (12%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G ++  RQEA+  L+   H   G FLVR+S T  GDY LS     +V+H  I     
Sbjct: 14  WYMGPVS--RQEAQTRLQGQRH---GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQ 648
           R   +F + D   FD L  L+  Y+ H L +     TL EP P+
Sbjct: 69  R---RFKIGDQE-FDHLPALLEFYKIHYLDT----TTLIEPAPR 104


>AC069137-1|AAY24097.1|  392|Homo sapiens unknown protein.
          Length = 392

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 36/106 (33%), Positives = 54/106 (50%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 278 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 336

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K + GWW G   GK+ H FPA YV E+
Sbjct: 337 ARQDDELNLEKGDIVIIHEKKEGGWWFGSLNGKKGH-FPAAYVEEL 381


>AL121829-14|CAC15526.1|  488|Homo sapiens protein ( Human DNA
           sequence from clone RP4-697K14 on chromosome 20. ).
          Length = 488

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 649 PNKHEGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           P     + W+ +  +RTQA++LL    N  GAFL+RPSE   G +++S R + ++ H RV
Sbjct: 112 PETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRV 171

Query: 708 KQ--EGRLYTIGTVKFESLIELVSYYE 732
               +G LY      F  L EL++YY+
Sbjct: 172 SMAADGSLYLQKGRLFPGLEELLTYYK 198



 Score = 40.3 bits (90), Expect = 0.041
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 553 NRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYL 612
           +R +A+ LL +  +   G FL+R S + +G Y LS   Q KV H R+ +  +  +   YL
Sbjct: 126 SRTQAQQLLLSPPN-EPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL---YL 181

Query: 613 IDSMCFDSLYNLITHYRSH 631
                F  L  L+T+Y+++
Sbjct: 182 QKGRLFPGLEELLTYYKAN 200


>CR457167-1|CAG33448.1|  430|Homo sapiens HIP-55 protein.
          Length = 430

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 28/51 (54%), Positives = 34/51 (66%), Gaps = 2/51 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYV 831
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYV 426


>U09812-1|AAA78806.1|   59|Homo sapiens protein ( Human
           phospholipase C-like gene, partial cds. ).
          Length = 59

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 25/54 (46%), Positives = 37/54 (68%), Gaps = 1/54 (1%)

Query: 701 EIKHCRVKQEGRLYTIGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRR 753
           ++KHCR+ ++      G    FESL+ELVSYYE H LY+K++L YP++ E + R
Sbjct: 4   KVKHCRINRDAGTLCWGPPPIFESLVELVSYYEKHSLYRKMRLCYPVTPELLER 57


>D25304-1|BAA04985.1|  773|Homo sapiens KIAA0006 protein.
          Length = 773

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 159 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 217

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 218 ERPLSPKAVKGFE 230


>BC043505-1|AAH43505.1|  538|Homo sapiens ARHGEF6 protein protein.
          Length = 538

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 8   QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 66

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 67  ERPLSPKAVKGFE 79


>BC039856-1|AAH39856.1|  776|Homo sapiens Rac/Cdc42 guanine
           nucleotide exchange factor (GEF) 6 protein.
          Length = 776

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 162 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 220

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 221 ERPLSPKAVKGFE 233


>AM491363-1|CAM33013.1|  498|Homo sapiens bcr-abl1 e19a2 chimeric
           protein protein.
          Length = 498

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 372 NSLEKHSWYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 430

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 431 ASDGKLYVSSESRFNTLAELVHHH 454



 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 366 NYITPVNSLE-KHSWYHGPVS--RNAAEHLLSSGIN---GSFLVRESESSPGQRSISLRY 419

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 420 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 473

Query: 651 K 651
           K
Sbjct: 474 K 474


>AL683813-1|CAI39443.1|  776|Homo sapiens Rac/Cdc42 guanine
           nucleotide exchange factor (GEF) 6 protein.
          Length = 776

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 162 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 220

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 221 ERPLSPKAVKGFE 233


>AL135783-5|CAI42903.1|  622|Homo sapiens Rac/Cdc42 guanine
           nucleotide exchange factor (GEF) 6 protein.
          Length = 622

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 8   QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 66

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 67  ERPLSPKAVKGFE 79


>AL135783-1|CAI42899.1|  776|Homo sapiens Rac/Cdc42 guanine
           nucleotide exchange factor (GEF) 6 protein.
          Length = 776

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 162 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 220

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 221 ERPLSPKAVKGFE 233


>X16663-1|CAA34651.1|  486|Homo sapiens protein ( Human HS1 gene for
           heamatopoietic lineage cell specific protein. ).
          Length = 486

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 27/57 (47%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           ++  ALYDY+    DELSF    +IT+++  DEGWWRG   G     FPANYV  +E
Sbjct: 431 ISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-HFGLFPANYVKLLE 486


>BT006824-1|AAP35470.1|  486|Homo sapiens hematopoietic
           cell-specific Lyn substrate 1 protein.
          Length = 486

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 27/57 (47%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           ++  ALYDY+    DELSF    +IT+++  DEGWWRG   G     FPANYV  +E
Sbjct: 431 ISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-HFGLFPANYVKLLE 486


>BC016758-1|AAH16758.1|  486|Homo sapiens hematopoietic
           cell-specific Lyn substrate 1 protein.
          Length = 486

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 27/57 (47%), Positives = 35/57 (61%), Gaps = 1/57 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           ++  ALYDY+    DELSF    +IT+++  DEGWWRG   G     FPANYV  +E
Sbjct: 431 ISAVALYDYQGEGSDELSFDPDDVITDIEMVDEGWWRGRCHG-HFGLFPANYVKLLE 486


>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
           encoding p150 protein. ).
          Length = 1130

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 120 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 178

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 179 ASDGKLYVSSESRFNTLAELVHHH 202



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 114 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 167

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 168 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 221

Query: 651 K 651
           K
Sbjct: 222 K 222


>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
           tyrosine-protein kinase protein.
          Length = 1130

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 120 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 178

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 179 ASDGKLYVSSESRFNTLAELVHHH 202



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 114 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 167

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 168 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 221

Query: 651 K 651
           K
Sbjct: 222 K 222


>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
           tyrosine-protein kinase protein.
          Length = 1149

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 198 ASDGKLYVSSESRFNTLAELVHHH 221



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 133 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 186

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 187 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 240

Query: 651 K 651
           K
Sbjct: 241 K 241


>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 protein.
          Length = 1149

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 198 ASDGKLYVSSESRFNTLAELVHHH 221



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 133 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 186

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 187 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 240

Query: 651 K 651
           K
Sbjct: 241 K 241


>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 protein.
          Length = 1149

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 198 ASDGKLYVSSESRFNTLAELVHHH 221



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 133 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 186

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 187 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 240

Query: 651 K 651
           K
Sbjct: 241 K 241


>BC053878-1|AAH53878.1|  619|Homo sapiens zeta-chain (TCR)
           associated protein kinase 70kDa protein.
          Length = 619

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 4/82 (4%)

Query: 652 HEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           HE   W+H+  TR +AE +L     TDG FL+RP  KEQG++A+S    K + H  + Q+
Sbjct: 158 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRP-RKEQGTYALSLIYGKTVYHYLISQD 216

Query: 711 --GRLYTIGTVKFESLIELVSY 730
             G+       KF++L +LV Y
Sbjct: 217 KAGKYCIPEGTKFDTLWQLVEY 238



 Score = 32.7 bits (71), Expect = 8.2
 Identities = 19/56 (33%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIK 600
           +F+G ++  R EAE+ L+  A + DG FL+R+ +  +G Y LS     + +H  I+
Sbjct: 10  FFYGSIS--RAEAEEHLKL-AGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIE 62


>BC039039-1|AAH39039.1|  493|Homo sapiens ZAP70 protein protein.
          Length = 493

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 4/82 (4%)

Query: 652 HEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           HE   W+H+  TR +AE +L     TDG FL+RP  KEQG++A+S    K + H  + Q+
Sbjct: 32  HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRP-RKEQGTYALSLIYGKTVYHYLISQD 90

Query: 711 --GRLYTIGTVKFESLIELVSY 730
             G+       KF++L +LV Y
Sbjct: 91  KAGKYCIPEGTKFDTLWQLVEY 112


>AM491362-1|CAM33012.1|  585|Homo sapiens bcr-abl1 e6a2 chimeric
           protein protein.
          Length = 585

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 459 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 517

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 518 ASDGKLYVSSESRFNTLAELVHHH 541



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 453 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 506

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 507 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 560

Query: 651 K 651
           K
Sbjct: 561 K 561


>AM491361-1|CAM33011.1|  313|Homo sapiens bcr-abl1 e1a3 chimeric
           protein protein.
          Length = 313

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 187 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 245

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 246 ASDGKLYVSSESRFNTLAELVHHH 269



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 181 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 234

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 235 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 288

Query: 651 K 651
           K
Sbjct: 289 K 289


>AM491360-1|CAM33010.1|  260|Homo sapiens bcr-abl1 e14a3 chimeric
           protein protein.
          Length = 260

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 134 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 192

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 193 ASDGKLYVSSESRFNTLAELVHHH 216



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 128 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 181

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 182 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 235

Query: 651 K 651
           K
Sbjct: 236 K 236


>AM491359-1|CAM33009.1|  235|Homo sapiens bcr-abl1 e13a3 chimeric
           protein protein.
          Length = 235

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 109 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 167

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 168 ASDGKLYVSSESRFNTLAELVHHH 191



 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 103 NYITPANSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 156

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 157 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 210

Query: 651 K 651
           K
Sbjct: 211 K 211


>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 protein.
          Length = 1149

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 198 ASDGKLYVSSESRFNTLAELVHHH 221



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 133 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 186

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 187 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 240

Query: 651 K 651
           K
Sbjct: 241 K 241


>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 protein.
          Length = 1149

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 198 ASDGKLYVSSESRFNTLAELVHHH 221



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 133 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 186

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 187 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 240

Query: 651 K 651
           K
Sbjct: 241 K 241


>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 protein.
          Length = 1130

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 120 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 178

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 179 ASDGKLYVSSESRFNTLAELVHHH 202



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 114 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 167

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 168 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 221

Query: 651 K 651
           K
Sbjct: 222 K 222


>AJ131467-1|CAA10377.1|  307|Homo sapiens BCR/ABL chimeric fusion
           peptide protein.
          Length = 307

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 193 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 251

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 252 ASDGKLYVSSESRFNTLAELVHHH 275



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 187 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 240

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 241 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 294

Query: 651 K 651
           K
Sbjct: 295 K 295


>AJ131466-1|CAA10376.1|  332|Homo sapiens BCR/ABL (major breakpoint)
           fusion peptide protein.
          Length = 332

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 218 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 276

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 277 ASDGKLYVSSESRFNTLAELVHHH 300



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 212 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 265

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 266 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 319

Query: 651 K 651
           K
Sbjct: 320 K 320


>AF113911-1|AAD04633.1|  359|Homo sapiens BCR-ABL minor breakpoint
           peptide protein.
          Length = 359

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 245 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 303

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 304 ASDGKLYVSSESRFNTLAELVHHH 327



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 239 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 292

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 293 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 346

Query: 651 K 651
           K
Sbjct: 347 K 347


>AC016699-1|AAX93187.1|  493|Homo sapiens unknown protein.
          Length = 493

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 32/82 (39%), Positives = 47/82 (57%), Gaps = 4/82 (4%)

Query: 652 HEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           HE   W+H+  TR +AE +L     TDG FL+RP  KEQG++A+S    K + H  + Q+
Sbjct: 32  HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRP-RKEQGTYALSLIYGKTVYHYLISQD 90

Query: 711 --GRLYTIGTVKFESLIELVSY 730
             G+       KF++L +LV Y
Sbjct: 91  KAGKYCIPEGTKFDTLWQLVEY 112


>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
           leukemia viral oncogene homolog 1 isoform b variant
           protein.
          Length = 1167

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 157 NSLEKHSWYHGPVSRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 215

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 216 ASDGKLYVSSESRFNTLAELVHHH 239



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 151 NYITPVNSLE-KHSWYHGPVS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 204

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 205 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 258

Query: 651 K 651
           K
Sbjct: 259 K 259


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.136    0.416 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 174,547,297
Number of Sequences: 224733
Number of extensions: 7387695
Number of successful extensions: 20158
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 677
Number of HSP's successfully gapped in prelim test: 473
Number of HSP's that attempted gapping in prelim test: 17099
Number of HSP's gapped (non-prelim): 2396
length of query: 1201
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1103
effective length of database: 51,211,004
effective search space: 56485737412
effective search space used: 56485737412
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)