SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000600-TA|BGIBMGA000600-PA|IPR008973|C2
calcium/lipid-binding region, CaLB, IPR002048|Calcium-binding EF-hand,
IPR000008|C2 calcium-dependent membrane targeting, IPR000980|SH2
motif, IPR001452|Src homology-3,
IPR000909|Phosphatidylinositol-specific phospholipase C, X region,
IPR001711|Phosphatidylinositol-specific phospholipase C, Y domain,
IPR001849|Pleckstrin-like, IPR001192|Phosphoinositide-specific
phospholipase C, C-terminal (PLC),
IPR013841|Phosphatidylinositol-specific phospholipase C, X and Y boxes
         (1201 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;...  1552   0.0  
UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb...  1438   0.0  
UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R...  1272   0.0  
UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-...  1150   0.0  
UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...  1141   0.0  
UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|...  1078   0.0  
UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph...   812   0.0  
UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol...   803   0.0  
UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;...   700   0.0  
UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s...   654   0.0  
UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho...   357   1e-96
UniRef50_UPI0000E493A1 Cluster: PREDICTED: similar to phospholip...   266   2e-69
UniRef50_A7RPT6 Cluster: Predicted protein; n=2; Nematostella ve...   258   5e-67
UniRef50_Q3LUA8 Cluster: Phospholipase C-eta2; n=23; Euteleostom...   248   7e-64
UniRef50_O75038 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   248   7e-64
UniRef50_Q4KWH8 Cluster: Phospholipase C eta 1; n=45; Tetrapoda|...   244   1e-62
UniRef50_UPI000069FB22 Cluster: 1-phosphatidylinositol-4,5-bisph...   242   5e-62
UniRef50_UPI0000F1F4FE Cluster: PREDICTED: similar to phospholip...   238   6e-61
UniRef50_Q9BRC7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   237   2e-60
UniRef50_Q8K3R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   236   2e-60
UniRef50_UPI0000F1EF3B Cluster: PREDICTED: hypothetical protein;...   234   9e-60
UniRef50_A5D6R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   232   4e-59
UniRef50_Q8N3E9 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   231   9e-59
UniRef50_P51178 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   231   1e-58
UniRef50_Q4RX70 Cluster: Chromosome 11 SCAF14979, whole genome s...   225   6e-57
UniRef50_Q4SNU6 Cluster: Chromosome 15 SCAF14542, whole genome s...   223   2e-56
UniRef50_UPI000069F421 Cluster: phospholipase C delta 3; n=1; Xe...   220   2e-55
UniRef50_Q5QIB9 Cluster: Phospholipase C delta isoform; n=6; Str...   219   3e-55
UniRef50_UPI00006609DC Cluster: Homolog of Brachydanio rerio "Ph...   217   1e-54
UniRef50_Q86XJ2 Cluster: PLCH2 protein; n=8; Euteleostomi|Rep: P...   216   3e-54
UniRef50_UPI000065E113 Cluster: Homolog of Homo sapiens "PhosPho...   215   8e-54
UniRef50_O97037 Cluster: PLC-deltaH; n=1; Hydra magnipapillata|R...   212   4e-53
UniRef50_P40977 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   212   6e-53
UniRef50_Q9UPR0 Cluster: Inactive phospholipase C-like protein 2...   211   1e-52
UniRef50_A7SDH9 Cluster: Predicted protein; n=1; Nematostella ve...   210   2e-52
UniRef50_Q4RY83 Cluster: Chromosome 3 SCAF14978, whole genome sh...   207   2e-51
UniRef50_UPI000069E9FD Cluster: phospholipase C, delta 4; n=1; X...   205   7e-51
UniRef50_Q86YW0 Cluster: Phospholipase C zeta 1; n=7; Eutheria|R...   196   2e-48
UniRef50_Q08AQ7 Cluster: PLCZ1 protein; n=19; Amniota|Rep: PLCZ1...   196   2e-48
UniRef50_UPI0000EB12AF Cluster: phospholipase C-like 3; n=1; Can...   195   5e-48
UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholip...   194   1e-47
UniRef50_Q4RKI8 Cluster: Chromosome 21 SCAF15029, whole genome s...   193   2e-47
UniRef50_A0BLC4 Cluster: Chromosome undetermined scaffold_114, w...   192   4e-47
UniRef50_Q5CR08 Cluster: Phospholipase C, delta 1 ortholog with ...   192   5e-47
UniRef50_Q4RSB2 Cluster: Chromosome 13 SCAF15000, whole genome s...   192   6e-47
UniRef50_UPI000023F2A0 Cluster: hypothetical protein FG05898.1; ...   189   5e-46
UniRef50_A7RKT2 Cluster: Predicted protein; n=1; Nematostella ve...   188   6e-46
UniRef50_UPI0000E49F73 Cluster: PREDICTED: similar to KIAA1092 p...   188   1e-45
UniRef50_UPI00006CFB88 Cluster: Phosphatidylinositol-specific ph...   188   1e-45
UniRef50_Q4T850 Cluster: Chromosome 16 SCAF7896, whole genome sh...   185   6e-45
UniRef50_UPI000069FB24 Cluster: 1-phosphatidylinositol-4,5-bisph...   184   1e-44
UniRef50_UPI0000E817B6 Cluster: PREDICTED: hypothetical protein;...   183   2e-44
UniRef50_A7SXK4 Cluster: Predicted protein; n=1; Nematostella ve...   182   5e-44
UniRef50_A2QRK1 Cluster: Catalytic activity: 1-phosphatidyl-1D-m...   182   7e-44
UniRef50_Q02158 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   182   7e-44
UniRef50_UPI0000DB73F3 Cluster: PREDICTED: similar to no recepto...   180   2e-43
UniRef50_P78585 Cluster: Phosphoinositide-specific phospholipase...   180   2e-43
UniRef50_Q15147 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   180   3e-43
UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho...   179   4e-43
UniRef50_Q27J08 Cluster: Phospholipase C; n=1; Aplysia californi...   178   6e-43
UniRef50_Q21754 Cluster: Phospholipase c protein 4; n=2; Caenorh...   178   9e-43
UniRef50_UPI00006CB024 Cluster: Phosphatidylinositol-specific ph...   176   3e-42
UniRef50_A2TJ25 Cluster: Phospholipase C beta 3; n=8; Clupeoceph...   175   5e-42
UniRef50_Q5MG88 Cluster: Phospholipase C delta 1; n=2; Toxoplasm...   174   1e-41
UniRef50_Q9TZN8 Cluster: Phosphoinositide-specific phospholipase...   174   1e-41
UniRef50_Q8IA75 Cluster: Phospholipase c like protein 1, isoform...   173   3e-41
UniRef50_O97036 Cluster: PLC-betaH2; n=2; Eukaryota|Rep: PLC-bet...   172   4e-41
UniRef50_Q9NBA8 Cluster: Phospholipase C; n=3; Decapodiformes|Re...   171   1e-40
UniRef50_Q4S530 Cluster: Chromosome 6 SCAF14737, whole genome sh...   171   1e-40
UniRef50_O97035 Cluster: PLC-betaH1; n=1; Hydra magnipapillata|R...   170   2e-40
UniRef50_UPI000065E6FA Cluster: 1-phosphatidylinositol-4,5-bisph...   169   3e-40
UniRef50_A3LSB2 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   169   5e-40
UniRef50_P13217 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   169   5e-40
UniRef50_P25455 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   168   7e-40
UniRef50_A4IGD0 Cluster: Plcb3 protein; n=11; Euteleostomi|Rep: ...   168   9e-40
UniRef50_Q4S9T4 Cluster: Chromosome 2 SCAF14695, whole genome sh...   167   2e-39
UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome sh...   167   2e-39
UniRef50_Q16ZC0 Cluster: Phospholipase c epsilon; n=1; Aedes aeg...   167   2e-39
UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   167   2e-39
UniRef50_A7S279 Cluster: Predicted protein; n=1; Nematostella ve...   165   5e-39
UniRef50_Q4FXB0 Cluster: Phosphatidylinositol-specific phospholi...   165   9e-39
UniRef50_Q9NQ66 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   165   9e-39
UniRef50_Q9TVI2 Cluster: Putative uncharacterized protein plc-1;...   164   1e-38
UniRef50_Q4Q6Z7 Cluster: Phospholipase c-like protein; n=2; Leis...   163   3e-38
UniRef50_Q95X29 Cluster: Egg laying defective protein 8, isoform...   160   2e-37
UniRef50_A0C336 Cluster: Chromosome undetermined scaffold_146, w...   160   2e-37
UniRef50_A0CKY8 Cluster: Chromosome undetermined scaffold_20, wh...   156   3e-36
UniRef50_Q4TBY5 Cluster: Chromosome undetermined SCAF7071, whole...   156   4e-36
UniRef50_Q01970 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   156   4e-36
UniRef50_Q6CD33 Cluster: Similar to DEHA0A04554g Debaryomyces ha...   155   5e-36
UniRef50_Q5KJZ5 Cluster: Phosphoinositide phospholipase C, putat...   153   2e-35
UniRef50_Q4PA81 Cluster: Putative uncharacterized protein; n=1; ...   153   3e-35
UniRef50_O97033 Cluster: PLC-betaS; n=1; Ephydatia fluviatilis|R...   151   1e-34
UniRef50_Q75C92 Cluster: ACR024Wp; n=1; Eremothecium gossypii|Re...   151   1e-34
UniRef50_Q00722 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   151   1e-34
UniRef50_Q6FY00 Cluster: Similar to sp|P32383 Saccharomyces cere...   150   3e-34
UniRef50_A3KGF7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   149   3e-34
UniRef50_UPI00015A791C Cluster: UPI00015A791C related cluster; n...   149   5e-34
UniRef50_P32383 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   148   8e-34
UniRef50_A7TR21 Cluster: Putative uncharacterized protein; n=1; ...   147   1e-33
UniRef50_O13433 Cluster: 1-phosphatidylinositol-4,5-bisphosphate...   140   2e-31
UniRef50_UPI00015551EC Cluster: PREDICTED: hypothetical protein,...   135   8e-30
UniRef50_Q0UC00 Cluster: Putative uncharacterized protein; n=1; ...   134   1e-29
UniRef50_A5DAA1 Cluster: Putative uncharacterized protein; n=1; ...   134   2e-29
UniRef50_Q6CSI9 Cluster: Similar to sp|P32383 Saccharomyces cere...   129   4e-28
UniRef50_Q766D4 Cluster: Phosphoinositide-specific phospholipase...   125   8e-27
UniRef50_A7PP48 Cluster: Chromosome chr8 scaffold_23, whole geno...   124   1e-26
UniRef50_P93620 Cluster: Phosphoinositide-specific phospholipase...   124   1e-26
UniRef50_UPI0000F1F9F9 Cluster: PREDICTED: similar to 1-phosphat...   123   3e-26
UniRef50_Q762E2 Cluster: Phosphoinositide-specific phospholipase...   123   3e-26
UniRef50_Q56W08 Cluster: Phosphoinositide-specific phospholipase...   123   3e-26
UniRef50_Q8GV43 Cluster: Phosphoinositide-specific phospholipase...   122   8e-26
UniRef50_UPI0000E493BE Cluster: PREDICTED: similar to ENSANGP000...   120   2e-25
UniRef50_A7T500 Cluster: Predicted protein; n=4; cellular organi...   118   7e-25
UniRef50_Q4YWB8 Cluster: Phospholipase C-like, putative; n=4; Pl...   118   1e-24
UniRef50_Q944C1 Cluster: Phosphoinositide-specific phospholipase...   117   2e-24
UniRef50_Q9LUZ0 Cluster: Phosphoinositide-specific phospholipase...   116   3e-24
UniRef50_A5K7G0 Cluster: Phospholipase C-like, putative; n=3; Pl...   116   3e-24
UniRef50_Q8IJR0 Cluster: Phospholipase C-like, putative; n=1; Pl...   116   4e-24
UniRef50_A5AGR6 Cluster: Putative uncharacterized protein; n=1; ...   116   5e-24
UniRef50_Q9AXF1 Cluster: Phosphoinositide-specific phospholipase...   114   1e-23
UniRef50_A6RM87 Cluster: Putative uncharacterized protein; n=1; ...   113   2e-23
UniRef50_Q9XWB7 Cluster: Putative uncharacterized protein plc-2;...   110   2e-22
UniRef50_Q236T7 Cluster: Phosphatidylinositol-specific phospholi...   109   3e-22
UniRef50_UPI00015A74B5 Cluster: UPI00015A74B5 related cluster; n...   108   1e-21
UniRef50_A4S165 Cluster: Predicted protein; n=1; Ostreococcus lu...   107   2e-21
UniRef50_UPI0001555F0C Cluster: PREDICTED: hypothetical protein,...   103   3e-20
UniRef50_Q4QBH9 Cluster: Phosphoinositide-specific phospholipase...   102   7e-20
UniRef50_Q4SCY7 Cluster: Chromosome 14 SCAF14646, whole genome s...   101   9e-20
UniRef50_A5E691 Cluster: Putative uncharacterized protein; n=1; ...   101   2e-19
UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat...   100   3e-19
UniRef50_Q013R6 Cluster: Phosphoinositide-specific phospholipase...   100   3e-19
UniRef50_A7ASE0 Cluster: Phospholipase C gamma 1, putative; n=1;...   100   3e-19
UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty...    99   8e-19
UniRef50_Q0UE70 Cluster: Putative uncharacterized protein; n=4; ...    97   2e-18
UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ...    94   2e-17
UniRef50_A4RIZ5 Cluster: Putative uncharacterized protein; n=2; ...    92   1e-16
UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ...    91   1e-16
UniRef50_Q4N7P5 Cluster: Phospholipase C, putative; n=2; Theiler...    91   2e-16
UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept...    89   7e-16
UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;...    89   9e-16
UniRef50_Q2H4G2 Cluster: Putative uncharacterized protein; n=1; ...    86   5e-15
UniRef50_Q9STZ3 Cluster: 1-phosphatidylinositol-4, 5-bisphosphat...    85   8e-15
UniRef50_Q7SE08 Cluster: Putative uncharacterized protein NCU021...    85   1e-14
UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;...    83   3e-14
UniRef50_Q2H674 Cluster: Putative uncharacterized protein; n=1; ...    83   6e-14
UniRef50_UPI0000F1F414 Cluster: PREDICTED: hypothetical protein;...    82   1e-13
UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac...    82   1e-13
UniRef50_A4RFY5 Cluster: Putative uncharacterized protein; n=1; ...    81   1e-13
UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil...    81   2e-13
UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:...    80   4e-13
UniRef50_Q86YU7 Cluster: FLJ00417 protein; n=4; Tetrapoda|Rep: F...    80   4e-13
UniRef50_Q5IRA3 Cluster: Phosphatidyl inositol-specific phosphol...    80   4e-13
UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ...    80   4e-13
UniRef50_Q0UVV5 Cluster: Putative uncharacterized protein; n=1; ...    79   5e-13
UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad...    79   7e-13
UniRef50_UPI000023D8AD Cluster: hypothetical protein FG06693.1; ...    79   1e-12
UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot...    78   1e-12
UniRef50_A6RBI2 Cluster: Predicted protein; n=1; Ajellomyces cap...    77   3e-12
UniRef50_A2QEJ2 Cluster: Catalytic activity: 1-phosphatidyl-1D-m...    77   3e-12
UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh...    75   1e-11
UniRef50_Q5B933 Cluster: Putative uncharacterized protein; n=1; ...    75   1e-11
UniRef50_Q4WX21 Cluster: Phosphoinositide-specific phospholipase...    75   2e-11
UniRef50_Q1E522 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-11
UniRef50_Q0CXA3 Cluster: Putative uncharacterized protein; n=1; ...    75   2e-11
UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad...    74   3e-11
UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65...    74   3e-11
UniRef50_UPI0000DB7494 Cluster: PREDICTED: similar to CG10083-PA...    73   4e-11
UniRef50_UPI0000E80974 Cluster: PREDICTED: hypothetical protein;...    72   8e-11
UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase...    72   1e-10
UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept...    72   1e-10
UniRef50_UPI000023E2BC Cluster: hypothetical protein FG08790.1; ...    70   3e-10
UniRef50_A7EE08 Cluster: Putative uncharacterized protein; n=1; ...    70   3e-10
UniRef50_UPI0000D57984 Cluster: PREDICTED: similar to CG3637-PA;...    69   8e-10
UniRef50_Q966Z0 Cluster: Cortactin; n=1; Suberites domuncula|Rep...    69   1e-09
UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo...    69   1e-09
UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le...    68   1e-09
UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ...    68   2e-09
UniRef50_UPI0000F1F9FC Cluster: PREDICTED: similar to phospholip...    67   2e-09
UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - M...    67   2e-09
UniRef50_A7SYD1 Cluster: Predicted protein; n=2; Nematostella ve...    67   3e-09
UniRef50_A2VCM4 Cluster: PLCH2 protein; n=6; Tetrapoda|Rep: PLCH...    67   3e-09
UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;...    66   4e-09
UniRef50_Q0UVW3 Cluster: Putative uncharacterized protein; n=3; ...    66   4e-09
UniRef50_A6SRW9 Cluster: Putative uncharacterized protein; n=1; ...    66   4e-09
UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ...    66   5e-09
UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol...    66   5e-09
UniRef50_Q5AS57 Cluster: Putative uncharacterized protein; n=1; ...    66   5e-09
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul...    65   1e-08
UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin...    65   1e-08
UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase...    65   1e-08
UniRef50_Q4SVL5 Cluster: Chromosome undetermined SCAF13756, whol...    65   1e-08
UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-...    65   1e-08
UniRef50_A2QHI3 Cluster: Contig An03c0200, complete genome; n=3;...    64   2e-08
UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R...    64   2e-08
UniRef50_Q9P7E8 Cluster: Protein app1; n=2; Fungi/Metazoa group|...    64   2e-08
UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot...    64   3e-08
UniRef50_Q7SXH4 Cluster: Cortactin, like; n=3; Danio rerio|Rep: ...    63   4e-08
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole...    63   4e-08
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1...    63   4e-08
UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schis...    63   4e-08
UniRef50_Q2UPV5 Cluster: Predicted protein; n=2; Pezizomycotina|...    63   4e-08
UniRef50_Q14247 Cluster: Src substrate cortactin; n=44; Bilateri...    63   4e-08
UniRef50_UPI0000E1F7BD Cluster: PREDICTED: nitric oxide synthase...    63   5e-08
UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve...    63   5e-08
UniRef50_Q8IVI9 Cluster: Nostrin; n=22; Tetrapoda|Rep: Nostrin -...    63   5e-08
UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra...    62   7e-08
UniRef50_Q6GMH1 Cluster: Zgc:91835; n=1; Danio rerio|Rep: Zgc:91...    62   7e-08
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae...    62   9e-08
UniRef50_A1C8D2 Cluster: Actin binding protein, putative; n=4; E...    62   9e-08
UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2...    62   1e-07
UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s...    62   1e-07
UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A...    62   1e-07
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty...    61   2e-07
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi...    61   2e-07
UniRef50_Q9VDF4 Cluster: CG3637-PA; n=4; Diptera|Rep: CG3637-PA ...    61   2e-07
UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|...    61   2e-07
UniRef50_UPI0000E47D05 Cluster: PREDICTED: similar to MGC84047 p...    60   3e-07
UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange ...    60   3e-07
UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh...    60   3e-07
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099...    60   3e-07
UniRef50_Q9UJU6 Cluster: Drebrin-like protein; n=47; Euteleostom...    60   3e-07
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet...    60   3e-07
UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB...    60   4e-07
UniRef50_Q804J4 Cluster: Phospholipase C gamma 1; n=6; Danio rer...    60   4e-07
UniRef50_Q5M8F8 Cluster: Cortactin; n=2; Xenopus|Rep: Cortactin ...    60   4e-07
UniRef50_O00851 Cluster: Unconventional myosin IB; n=2; Entamoeb...    60   4e-07
UniRef50_A4R8V8 Cluster: Putative uncharacterized protein; n=2; ...    60   4e-07
UniRef50_UPI0000D558FE Cluster: PREDICTED: similar to CG10083-PA...    60   5e-07
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn...    60   5e-07
UniRef50_Q17M42 Cluster: Putative uncharacterized protein; n=1; ...    59   6e-07
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n...    59   6e-07
UniRef50_UPI00015B5756 Cluster: PREDICTED: similar to GA10060-PA...    59   8e-07
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco...    59   8e-07
UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus...    59   8e-07
UniRef50_O96459 Cluster: SRC8; n=2; Strongylocentrotus purpuratu...    59   8e-07
UniRef50_Q4S1M8 Cluster: Chromosome 6 SCAF14768, whole genome sh...    58   1e-06
UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted...    58   1e-06
UniRef50_Q12897 Cluster: Phospholipase C-like; n=16; Euteleostom...    58   1e-06
UniRef50_Q5KHY4 Cluster: Putative uncharacterized protein; n=1; ...    58   1e-06
UniRef50_P19706 Cluster: Myosin heavy chain IB; n=5; Eukaryota|R...    58   1e-06
UniRef50_Q6C2N2 Cluster: Class E vacuolar protein-sorting machin...    58   1e-06
UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy...    58   1e-06
UniRef50_A0JMM6 Cluster: Zgc:154014; n=11; Eumetazoa|Rep: Zgc:15...    58   1e-06
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    58   1e-06
UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat...    58   2e-06
UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H...    58   2e-06
UniRef50_Q6CEP4 Cluster: Yarrowia lipolytica chromosome B of str...    58   2e-06
UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor ...    58   2e-06
UniRef50_Q6GM14 Cluster: MGC84047 protein; n=9; Tetrapoda|Rep: M...    57   3e-06
UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol...    57   3e-06
UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:...    57   3e-06
UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s...    57   3e-06
UniRef50_Q4S596 Cluster: Chromosome 19 SCAF14731, whole genome s...    57   3e-06
UniRef50_P14317 Cluster: Hematopoietic lineage cell-specific pro...    57   3e-06
UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E...    57   3e-06
UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ...    57   3e-06
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E...    57   3e-06
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr...    57   3e-06
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ...    57   3e-06
UniRef50_UPI0000EB037D Cluster: Hematopoietic lineage cell-speci...    56   4e-06
UniRef50_Q5ZMV0 Cluster: Putative uncharacterized protein; n=2; ...    56   4e-06
UniRef50_Q9XUT0 Cluster: Putative uncharacterized protein; n=2; ...    56   4e-06
UniRef50_Q16NH5 Cluster: Cortactin; n=1; Aedes aegypti|Rep: Cort...    56   4e-06
UniRef50_A6RRT4 Cluster: Putative uncharacterized protein; n=3; ...    56   4e-06
UniRef50_UPI00005A2ADA Cluster: PREDICTED: similar to drebrin-li...    56   6e-06
UniRef50_Q4TEV6 Cluster: Chromosome undetermined SCAF5071, whole...    56   6e-06
UniRef50_Q16H73 Cluster: Putative uncharacterized protein; n=1; ...    56   6e-06
UniRef50_Q5VSN0 Cluster: SH3-domain kinase binding protein 1; n=...    56   6e-06
UniRef50_Q96B97 Cluster: SH3 domain-containing kinase-binding pr...    56   6e-06
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr...    56   6e-06
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut...    56   6e-06
UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain...    56   8e-06
UniRef50_Q9Y0S9 Cluster: CG9749-PA; n=7; Endopterygota|Rep: CG97...    56   8e-06
UniRef50_A5E386 Cluster: Reduced viability upon starvation prote...    56   8e-06
UniRef50_Q4RUM3 Cluster: Chromosome 12 SCAF14993, whole genome s...    55   1e-05
UniRef50_Q9DAC8 Cluster: Adult male testis cDNA, RIKEN full-leng...    55   1e-05
UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ...    55   1e-05
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos...    55   1e-05
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal...    55   1e-05
UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy...    55   1e-05
UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym...    55   1e-05
UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor...    55   1e-05
UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda...    55   1e-05
UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|...    55   1e-05
UniRef50_Q9VU84 Cluster: Drebrin-like protein; n=3; Coelomata|Re...    55   1e-05
UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella ve...    54   2e-05
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut...    54   2e-05
UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor ...    54   2e-05
UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no...    54   2e-05
UniRef50_A1YTM4 Cluster: Intersectin; n=1; Lampetra fluviatilis|...    54   2e-05
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    54   2e-05
UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ...    54   2e-05
UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s...    54   2e-05
UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ...    54   2e-05
UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote...    54   2e-05
UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac...    54   3e-05
UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy...    54   3e-05
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man...    54   3e-05
UniRef50_Q5DAS3 Cluster: SJCHGC02119 protein; n=1; Schistosoma j...    54   3e-05
UniRef50_Q4PAN1 Cluster: Putative uncharacterized protein; n=1; ...    54   3e-05
UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int...    54   3e-05
UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor ...    54   3e-05
UniRef50_UPI0000D9C236 Cluster: PREDICTED: abl-interactor 1 isof...    53   4e-05
UniRef50_UPI000051AA4C Cluster: PREDICTED: similar to rho-type g...    53   4e-05
UniRef50_A7RXM7 Cluster: Predicted protein; n=1; Nematostella ve...    53   4e-05
UniRef50_Q59G41 Cluster: Abl-interactor 1 variant; n=46; Eumetaz...    53   4e-05
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ...    53   4e-05
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop...    53   4e-05
UniRef50_UPI000065F8ED Cluster: SH3-containing GRB2-like protein...    53   5e-05
UniRef50_Q4SCY6 Cluster: Chromosome 14 SCAF14646, whole genome s...    53   5e-05
UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh...    53   5e-05
UniRef50_Q59PV2 Cluster: Putative uncharacterized protein; n=3; ...    53   5e-05
UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost...    53   5e-05
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung...    53   5e-05
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA...    52   7e-05
UniRef50_UPI00006CBE11 Cluster: C2 domain containing protein; n=...    52   7e-05
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol...    52   7e-05
UniRef50_Q4S5H4 Cluster: Chromosome 3 SCAF14730, whole genome sh...    52   7e-05
UniRef50_Q556K1 Cluster: Putative uncharacterized protein; n=2; ...    52   7e-05
UniRef50_A0NFK4 Cluster: ENSANGP00000030373; n=2; Coelomata|Rep:...    52   7e-05
UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep: ...    52   7e-05
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat...    52   7e-05
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae...    52   7e-05
UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p...    52   1e-04
UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA...    52   1e-04
UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s...    52   1e-04
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C...    52   1e-04
UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb...    52   1e-04
UniRef50_P10569 Cluster: Myosin IC heavy chain; n=4; Eukaryota|R...    52   1e-04
UniRef50_Q6BNP6 Cluster: Class E vacuolar protein-sorting machin...    52   1e-04
UniRef50_Q5A895 Cluster: Class E vacuolar protein-sorting machin...    52   1e-04
UniRef50_UPI0000E47242 Cluster: PREDICTED: hypothetical protein;...    52   1e-04
UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n...    52   1e-04
UniRef50_UPI000065D63E Cluster: Hematopoietic lineage cell-speci...    52   1e-04
UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut...    52   1e-04
UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome sh...    52   1e-04
UniRef50_Q9VIN1 Cluster: CG10043-PA, isoform A; n=6; Diptera|Rep...    52   1e-04
UniRef50_Q9VIF7 Cluster: CG1099-PA, isoform A; n=8; Sophophora|R...    52   1e-04
UniRef50_Q6T3S4 Cluster: AbpE; n=4; Dictyostelium discoideum|Rep...    52   1e-04
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd...    52   1e-04
UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;...    52   1e-04
UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein ...    52   1e-04
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ...    52   1e-04
UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    52   1e-04
UniRef50_Q8CBW3 Cluster: Abl interactor 1; n=74; Euteleostomi|Re...    52   1e-04
UniRef50_UPI0000E498C8 Cluster: PREDICTED: similar to SH3-domain...    51   2e-04
UniRef50_UPI0000E47DD5 Cluster: PREDICTED: similar to endophilin...    51   2e-04
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p...    51   2e-04
UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain...    51   2e-04
UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s...    51   2e-04
UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j...    51   2e-04
UniRef50_A7S0K6 Cluster: Predicted protein; n=1; Nematostella ve...    51   2e-04
UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am...    51   2e-04
UniRef50_A5DS28 Cluster: Putative uncharacterized protein; n=1; ...    51   2e-04
UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    51   2e-04
UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B...    51   2e-04
UniRef50_UPI00015B47B7 Cluster: PREDICTED: similar to ENSANGP000...    51   2e-04
UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti...    51   2e-04
UniRef50_UPI00006CBE10 Cluster: conserved hypothetical protein; ...    51   2e-04
UniRef50_Q7PWA1 Cluster: ENSANGP00000005190; n=2; Culicidae|Rep:...    51   2e-04
UniRef50_Q400L7 Cluster: Putative uncharacterized protein; n=4; ...    51   2e-04
UniRef50_A6QS61 Cluster: Predicted protein; n=1; Ajellomyces cap...    51   2e-04
UniRef50_A5DTH4 Cluster: Putative uncharacterized protein; n=1; ...    51   2e-04
UniRef50_Q8N157 Cluster: Jouberin; n=40; Eumetazoa|Rep: Jouberin...    51   2e-04
UniRef50_UPI00015B4161 Cluster: PREDICTED: hypothetical protein;...    50   3e-04
UniRef50_UPI0000E4A632 Cluster: PREDICTED: similar to Syt7 prote...    50   3e-04
UniRef50_UPI000069E2B7 Cluster: UPI000069E2B7 related cluster; n...    50   3e-04
UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Interse...    50   3e-04
UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC...    50   3e-04
UniRef50_O08635 Cluster: SH3 domain protein D19; n=17; Tetrapoda...    50   3e-04
UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h...    50   3e-04
UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ...    50   3e-04
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty...    50   3e-04
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ...    50   3e-04
UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p...    50   3e-04
UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve...    50   3e-04
UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=...    50   3e-04
UniRef50_Q0UD52 Cluster: Putative uncharacterized protein; n=1; ...    50   3e-04
UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra...    50   3e-04
UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A...    50   3e-04
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX...    50   3e-04
UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei...    50   4e-04
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty...    50   4e-04
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92...    50   4e-04
UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh...    50   4e-04
UniRef50_Q5BXE8 Cluster: SJCHGC01829 protein; n=3; Schistosoma j...    50   4e-04
UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:...    50   4e-04
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ...    50   4e-04
UniRef50_Q9NYB9 Cluster: Abl interactor 2; n=103; Euteleostomi|R...    50   4e-04
UniRef50_UPI0000E81EFA Cluster: PREDICTED: hypothetical protein;...    50   5e-04
UniRef50_UPI0000ECBBF3 Cluster: Drebrin-like protein (SH3 domain...    50   5e-04
UniRef50_Q4R4C1 Cluster: Testis cDNA clone: QtsA-11117, similar ...    50   5e-04
UniRef50_Q5DEG7 Cluster: SJCHGC01831 protein; n=1; Schistosoma j...    50   5e-04
UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve...    50   5e-04
UniRef50_A7RQF8 Cluster: Predicted protein; n=1; Nematostella ve...    50   5e-04
UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat...    50   5e-04
UniRef50_P34416 Cluster: LIM and SH3 domain protein F42H10.3; n=...    50   5e-04
UniRef50_P38753 Cluster: Class E vacuolar protein-sorting machin...    50   5e-04
UniRef50_O94868 Cluster: FCH and double SH3 domains protein 2; n...    50   5e-04
UniRef50_UPI00015B4F0B Cluster: PREDICTED: similar to Jak pathwa...    49   7e-04
UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,...    49   7e-04
UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73...    49   7e-04
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1...    49   7e-04
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol...    49   7e-04
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia...    49   7e-04
UniRef50_Q54DN5 Cluster: SH3 domain-containing protein; n=2; Dic...    49   7e-04
UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve...    49   7e-04
UniRef50_Q6C963 Cluster: Yarrowia lipolytica chromosome D of str...    49   7e-04
UniRef50_Q2H2P1 Cluster: Putative uncharacterized protein; n=1; ...    49   7e-04
UniRef50_A6R7Z9 Cluster: Putative uncharacterized protein; n=1; ...    49   7e-04
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther...    49   7e-04
UniRef50_Q75DS3 Cluster: Class E vacuolar protein-sorting machin...    49   7e-04
UniRef50_UPI0001555A82 Cluster: PREDICTED: similar to Cortactin,...    49   9e-04
UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;...    49   9e-04
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p...    49   9e-04
UniRef50_UPI0000E483A8 Cluster: PREDICTED: similar to plenty of ...    49   9e-04
UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid...    49   9e-04
UniRef50_UPI00004D5D63 Cluster: Jouberin (Abelson helper integra...    49   9e-04
UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro...    49   9e-04
UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc...    49   9e-04
UniRef50_Q4RMS9 Cluster: Chromosome 3 SCAF15018, whole genome sh...    49   9e-04
UniRef50_Q5U3B8 Cluster: SH3D19 protein; n=24; Amniota|Rep: SH3D...    49   9e-04
UniRef50_Q9UNF0 Cluster: Protein kinase C and casein kinase subs...    49   9e-04
UniRef50_UPI0000E4836F Cluster: PREDICTED: hypothetical protein;...    48   0.001
UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro...    48   0.001
UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh...    48   0.001
UniRef50_Q32LS7 Cluster: Zgc:123285; n=2; Danio rerio|Rep: Zgc:1...    48   0.001
UniRef50_Q9XTL2 Cluster: CG6521-PA; n=2; Sophophora|Rep: CG6521-...    48   0.001
UniRef50_Q8MML2 Cluster: SYNAPTIC DYNAMIN-ASSOCIATED PROTEIN IIB...    48   0.001
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m...    48   0.001
UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ...    48   0.001
UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra...    48   0.001
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote...    48   0.001
UniRef50_Q10199 Cluster: Septation protein imp2; n=1; Schizosacc...    48   0.001
UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro...    48   0.001
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel...    48   0.001
UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ...    48   0.002
UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;...    48   0.002
UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA...    48   0.002
UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ...    48   0.002
UniRef50_UPI000066017A Cluster: nitric oxide synthase traffickin...    48   0.002
UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1...    48   0.002
UniRef50_Q75JD4 Cluster: Similar to Xenopus laevis (African claw...    48   0.002
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g...    48   0.002
UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j...    48   0.002
UniRef50_Q2H8X6 Cluster: Putative uncharacterized protein; n=1; ...    48   0.002
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd...    48   0.002
UniRef50_Q6CVA8 Cluster: Class E vacuolar protein-sorting machin...    48   0.002
UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto...    48   0.002
UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ...    48   0.002
UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome s...    48   0.002
UniRef50_A1L2S0 Cluster: LOC100036932 protein; n=3; Xenopus|Rep:...    48   0.002
UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc...    48   0.002
UniRef50_Q9VA36 Cluster: CG31012-PC, isoform C; n=9; Sophophora|...    48   0.002
UniRef50_Q9BHE8 Cluster: C2 domain protein; n=2; Leishmania|Rep:...    48   0.002
UniRef50_Q8T7Z1 Cluster: Mlk (Mixed lineage kinase) homolog prot...    48   0.002
UniRef50_Q8T7Z0 Cluster: Mlk (Mixed lineage kinase) homolog prot...    48   0.002
UniRef50_Q21430 Cluster: Putative uncharacterized protein pix-1;...    48   0.002
UniRef50_A0BND2 Cluster: Chromosome undetermined scaffold_118, w...    48   0.002
UniRef50_Q6CD36 Cluster: Similar to sp|P53281 Saccharomyces cere...    48   0.002
UniRef50_Q6BK14 Cluster: Similar to sp|P47068 Saccharomyces cere...    48   0.002
UniRef50_Q5K6X7 Cluster: Cell division control protein 25, putat...    48   0.002
UniRef50_Q4P3H3 Cluster: Putative uncharacterized protein; n=1; ...    48   0.002
UniRef50_A6REM5 Cluster: Predicted protein; n=1; Ajellomyces cap...    48   0.002
UniRef50_P39743 Cluster: Reduced viability upon starvation prote...    48   0.002
UniRef50_Q4P5J4 Cluster: Class E vacuolar protein-sorting machin...    48   0.002
UniRef50_UPI0000E465C3 Cluster: PREDICTED: hypothetical protein;...    47   0.003
UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ...    47   0.003
UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain...    47   0.003
UniRef50_UPI0000ECA839 Cluster: UPI0000ECA839 related cluster; n...    47   0.003
UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G...    47   0.003
UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol...    47   0.003
UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh...    47   0.003
UniRef50_Q5C288 Cluster: SJCHGC09127 protein; n=1; Schistosoma j...    47   0.003
UniRef50_A7SAV1 Cluster: Predicted protein; n=1; Nematostella ve...    47   0.003
UniRef50_Q1DZA2 Cluster: Putative uncharacterized protein; n=1; ...    47   0.003
UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E...    47   0.003
UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator...    47   0.003
UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10...    47   0.003
UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain...    47   0.004
UniRef50_UPI00006CA823 Cluster: Variant SH3 domain containing pr...    47   0.004
UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n...    47   0.004
UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n...    47   0.004
UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R...    47   0.004
UniRef50_Q6DBQ9 Cluster: Zgc:91999; n=7; Danio rerio|Rep: Zgc:91...    47   0.004
UniRef50_Q4SID9 Cluster: Chromosome 5 SCAF14581, whole genome sh...    47   0.004
UniRef50_Q4RZ53 Cluster: Chromosome 7 SCAF14966, whole genome sh...    47   0.004
UniRef50_Q07DM1 Cluster: Ahi1; n=2; Danio rerio|Rep: Ahi1 - Dani...    47   0.004
UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j...    47   0.004
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS...    47   0.004
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En...    47   0.004
UniRef50_Q12965 Cluster: Myosin-Ie; n=48; Bilateria|Rep: Myosin-...    47   0.004
UniRef50_Q0U6X7 Cluster: Class E vacuolar protein-sorting machin...    47   0.004
UniRef50_UPI00015B5DE3 Cluster: PREDICTED: hypothetical protein;...    46   0.005
UniRef50_UPI00015A734B Cluster: SH3 multiple domains 2 like; n=1...    46   0.005
UniRef50_A5D8S5 Cluster: Si:dkey-15j16.4 protein; n=10; Euteleos...    46   0.005
UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ...    46   0.005
UniRef50_Q17IU1 Cluster: Signal transducing adapter molecule; n=...    46   0.005
UniRef50_A7T2F6 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ...    46   0.005

>UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA; n=1;
            Tribolium castaneum|Rep: PREDICTED: similar to CG4200-PA
            - Tribolium castaneum
          Length = 1233

 Score = 1552 bits (3848), Expect = 0.0
 Identities = 704/1194 (58%), Positives = 918/1194 (76%), Gaps = 17/1194 (1%)

Query: 14   IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
            I E +Q+IS +ERG+ V+K+  RK+ E + L +RRET Q++W+R     +  ++GA+D+R
Sbjct: 39   IPEMEQIISQLERGTLVMKYSLRKKAEHKTLAIRRETRQIVWTRPATNSKPVHDGAVDLR 98

Query: 74   DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
             +KE+R GKSSKDF++W +++K++E+ KCF +YYG+EFKLR  S  A ++KECE WVKG+
Sbjct: 99   KIKEIRLGKSSKDFDKWADDSKKIENLKCFVVYYGSEFKLRVLSIAALSEKECELWVKGL 158

Query: 134  LYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQ 193
             YL+ + ++  YPLQ++ WLR+EFY++EN  E I +K++KAFLP+IN KI T+KLR++F 
Sbjct: 159  RYLVKDTINVPYPLQVQVWLRREFYAMENPTETINIKDLKAFLPRINYKIPTNKLRELFN 218

Query: 194  DVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQH 253
            +VDT KR EIGFDDFAVLYQK+IFDE+N  +IFDK ++Y SN  +++L+E Q+FL  EQ+
Sbjct: 219  EVDTRKRAEIGFDDFAVLYQKIIFDESNGAEIFDKLALYSSNLKSVSLQEVQSFLAKEQN 278

Query: 254  DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313
            D+L +D+   S+FI D+L+DPQR++ EP+FT+SEF++ L+SKQN ++D   D V QDM++
Sbjct: 279  DDLSNDDRAVSRFICDFLKDPQREVQEPHFTISEFLDYLFSKQNDLWDPNKDSVHQDMSK 338

Query: 314  PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373
            PLSHYWI+SSHNTYLTGDQ SSESS+EAY RCLR GCRCIELDCWDGPDG PFIYHGHT 
Sbjct: 339  PLSHYWIASSHNTYLTGDQLSSESSVEAYARCLRMGCRCIELDCWDGPDGMPFIYHGHTF 398

Query: 374  TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433
            TTKI+FMDV++TIKEHAF TSEYP+ILSIEDNCSLPQQR+MA+A Q+VFG+ LL HP++K
Sbjct: 399  TTKIKFMDVIKTIKEHAFATSEYPVILSIEDNCSLPQQRKMATAMQEVFGESLLTHPVEK 458

Query: 434  NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDK 493
            NE  LPSP+             PEG +ESS  + + EG ++DLR+S +NGI++LEDPVDK
Sbjct: 459  NEKQLPSPYQLRRRIILKHKKLPEGQDESSSILIRHEGSEMDLRSSFRNGIMYLEDPVDK 518

Query: 494  EWKPHAFVLTENKLYYTESY-----NSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHG 548
            EW PH FVLTENKL+YT+SY     + +               + VP +ELHF+E WFHG
Sbjct: 519  EWNPHFFVLTENKLFYTDSYKPDQESERSEDEDDSAAAFHRSKSDVPNEELHFSEKWFHG 578

Query: 549  KLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVT 608
            KLA  R+EAE LL+A++HLGDGTFLVR SVTFVG+YCLSFWR G+VNHCRI+ K ++  T
Sbjct: 579  KLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSKPDKQHT 638

Query: 609  KFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAE 668
            ++YL D+  FDSLY+LITHYR+ PL + EF ITL+EPVPQP KHE +EW+H H  + QA+
Sbjct: 639  RYYLTDAKYFDSLYSLITHYRNCPLVTAEFSITLQEPVPQPKKHETEEWYHKHTGKMQAD 698

Query: 669  ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELV 728
            E+LR+   +GAFLVRPSE +   + ISFR +K+IKHCR+K EGRLYTIG V+FESL+EL+
Sbjct: 699  EILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLYTIGNVEFESLVELI 758

Query: 729  SYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVY-GTPGYMDPTSFT-SKVTVKALYD 786
            +YYENHPLY++VKL YPISEE V+R+  + DDN  Y  +P YMDP++FT  K+TVKALYD
Sbjct: 759  NYYENHPLYRRVKLSYPISEEAVKRMTMQ-DDNVGYNSSPSYMDPSAFTPPKITVKALYD 817

Query: 787  YRARQDDELSFCKHAIITNVDKPDE--GWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTS 844
            YRA+Q DELSFCKHAIITNV KP+   GWWRGDYGG + H+FPANYV+E++   + D   
Sbjct: 818  YRAQQPDELSFCKHAIITNVTKPENSPGWWRGDYGGMKQHFFPANYVMELDRMESQD--- 874

Query: 845  GLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATRESA 904
            G ++ S    S+ +G LD+ GA+V+L+         W+V++ +    +P ++A  +RE A
Sbjct: 875  GSDDGSGE--SMLQGQLDMNGAVVDLIHHPERPGLEWVVKIVTSTACTPLEVALQSREMA 932

Query: 905  LEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNE 964
            +EW                   +MERT+RIAKE+S+LIIYCRS+TFNIER R +GF++ E
Sbjct: 933  VEWMLAIKEVAQRACALENHHREMERTFRIAKEMSNLIIYCRSITFNIERARQQGFIFYE 992

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            MSSFPETKAE+LM QQE  FFVKYH  Q SR+YPKGQR+DSSNYNP+  WN GSQMVALN
Sbjct: 993  MSSFPETKAEKLMCQQEKKFFVKYHQHQFSRVYPKGQRVDSSNYNPINMWNIGSQMVALN 1052

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084
            YQT DKPMQ+N  KF+ NG CG++LKP FMF + ++P D+ ++ G V+P  V LR+I AR
Sbjct: 1053 YQTGDKPMQLNQAKFRDNGNCGYLLKPDFMFRDDFDPADRNTLVG-VEPWIVTLRIIAAR 1111

Query: 1085 HLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW-NDICEFEVANPELALI 1143
            HL +  +GTASPFVEVE+IGA +DSG KL TK V+DNG NP W  ++ EF V NP  AL+
Sbjct: 1112 HLFRPKKGTASPFVEVEVIGAPFDSGTKLSTKPVTDNGFNPRWMEEVIEFPVYNPYFALL 1171

Query: 1144 RFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            RFVVQDED+FGEPNFIGQAT+P+ CLR GYRSV L NA+SE+LEL++L++H+SI
Sbjct: 1172 RFVVQDEDVFGEPNFIGQATYPVTCLRTGYRSVWLKNAYSEDLELASLLIHISI 1225


>UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae
            str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae
            str. PEST
          Length = 1230

 Score = 1438 bits (3563), Expect = 0.0
 Identities = 682/1213 (56%), Positives = 866/1213 (71%), Gaps = 37/1213 (3%)

Query: 16   EADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDV 75
            E +Q+I  +ERG+ + KF+PRKRPE++ L +RRET Q++WS +    R  YEG+L++R+V
Sbjct: 18   EMEQIICQLERGTLIQKFYPRKRPEKKTLMLRRETRQIIWSSVQTNGRSNYEGSLELREV 77

Query: 76   KEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLY 135
            KEVR GK SKDFE+WPEE K+ E  KCF I +G +FKLR  S VA ++KE + W+KG+ Y
Sbjct: 78   KEVRPGKKSKDFEKWPEEAKKSEPRKCFVILHGNDFKLRTVSIVAFSEKEADMWLKGLKY 137

Query: 136  LIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV 195
            LI++ VSA Y LQIERWLR+EFY +E ++   +LK+V++FLPKINCKIST+KL +VF +V
Sbjct: 138  LISDTVSAPYWLQIERWLRREFYLME-ANGTASLKDVRSFLPKINCKISTAKLNEVFHEV 196

Query: 196  DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFD--KYSVYCSNGTTITLREFQNFLRDEQH 253
            DT +R E+GFDDF  LYQ+LI    ++ + FD  + + Y  NG T+TL+EF+ FL  EQ 
Sbjct: 197  DTRRRNELGFDDFTRLYQRLILPPASLPEYFDGLRMATYSQNGETVTLQEFRRFLTKEQQ 256

Query: 254  DNLGD-----DEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308
            ++ G       E   ++FI DY++DP RD+ EPY  L EF++ L+S+QN I+D + D V 
Sbjct: 257  EDEGSPGGGHSEETVAKFINDYIQDPARDVSEPYLRLHEFIDFLFSRQNEIWDKRCDTVY 316

Query: 309  QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
            QDM+RPL+HYWISSSHNTYLTGDQFSSESS+EAY R LR GCRCIELDCWDGPD  P I+
Sbjct: 317  QDMSRPLAHYWISSSHNTYLTGDQFSSESSVEAYARALRMGCRCIELDCWDGPDNMPLIF 376

Query: 369  HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
            HGHT TT+I+FMDV+RTIKEHAFITSEYPLILSIE NCSL QQRRMA A  +VFG++LL 
Sbjct: 377  HGHTFTTRIKFMDVIRTIKEHAFITSEYPLILSIEQNCSLTQQRRMAQAMLEVFGEMLLT 436

Query: 429  HPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--------EESSFAVRQEEGKDLDLRNSI 480
             P+DK E  LPSP              PE          +ES+  +R  +  +LD+RN++
Sbjct: 437  QPIDKAEAQLPSPQQLKRKIILKHKKLPENGMLVVDEAGKESAVLMRGNDESELDIRNTV 496

Query: 481  KNGILHLEDPVDKEWKPHAFVLTENKLYYTESY---------NSQXXXXXXXXXXXXXXN 531
            KNGIL+LEDPVDK W  H FVLT++KL+YT+S          + +               
Sbjct: 497  KNGILYLEDPVDKGWNAHFFVLTQHKLFYTDSQRPDRDADGRDDEREENGFATNRQSRDG 556

Query: 532  AIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ 591
            A++  DELHF E WFHGKL+G R+EAE LL+  +HLGDGTFLVRESVTFVGDYCLSFWRQ
Sbjct: 557  AVLSNDELHFGENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQ 616

Query: 592  GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNK 651
            GK NHCRIKLKQ++GVTK+YL++++ F+SLY+LI +YR + LRS EF ITLKEPVPQPNK
Sbjct: 617  GKPNHCRIKLKQDKGVTKYYLMENVLFESLYSLIMYYRQNALRSAEFYITLKEPVPQPNK 676

Query: 652  HEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEG 711
            HE KEW+H   TR Q+E +L +   DGAFLVRPSEK   +F ISFR   + KHCR++ EG
Sbjct: 677  HETKEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEG 736

Query: 712  RLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL----VS-EPDDNTVYGT 766
            RLY +G ++FESL++LV++Y  HPLY+KV L YPI  E +RR+    VS  P      G 
Sbjct: 737  RLYEMGGMEFESLVDLVNFYSKHPLYRKVTLTYPIPREMIRRINTMDVSCGPPVPEESGG 796

Query: 767  PGYMDPTSFTSK-VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHW 825
             GYMDP + T++ VTVKALYDY+A++DDELSFCKHAIITNV K    WW GDYGGKR H+
Sbjct: 797  YGYMDPATVTNENVTVKALYDYKAQRDDELSFCKHAIITNVVKRGNDWWLGDYGGKRQHY 856

Query: 826  FPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRV 885
            FPANYV E+       +     NE   LGSLQKG LDV GA+VE+   +     R ++R+
Sbjct: 857  FPANYVQELSAMDDGTLVEEGANEPLMLGSLQKGSLDVHGAVVEMAYSNHPDIER-ILRI 915

Query: 886  QSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYC 945
            Q+P M + F++   T+E A EW                   KMER  R+AKE+SDLIIYC
Sbjct: 916  QNPTMQNVFEVGVQTKELAYEWMCAIKEAAQNASAMENERRKMERNSRVAKEMSDLIIYC 975

Query: 946  RSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQE-NTFFVKYHTTQLSRIYPKGQRID 1004
            RSV F   +     +V+ EMSSFPETKAE+   Q E    FV+YH   LSR+YPKGQR+D
Sbjct: 976  RSVPF---KHHPAAWVFYEMSSFPETKAEKYFLQAETRALFVRYHRNHLSRVYPKGQRLD 1032

Query: 1005 SSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK 1064
            SSNY+P   WNCGSQM+ALN+QTPDKPMQ+N  KF+ NGGCG++LKP+FMF + ++P D 
Sbjct: 1033 SSNYHPTALWNCGSQMIALNFQTPDKPMQLNQAKFRDNGGCGYLLKPEFMFRDEFDPTDP 1092

Query: 1065 KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLN 1124
             ++ G V  V V +R+IG R+LCK  R   SP VEVE++GA +D G+K  T+ ++DNGLN
Sbjct: 1093 NTLVG-VGEVIVNVRIIGGRNLCKVSRNITSPLVEVEVLGASFDGGIKHRTRAIADNGLN 1151

Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184
            P+WN+ICEF +ANP  A+IRF VQDED+FGEPNFIGQA FPL  +R GYRSV L N +SE
Sbjct: 1152 PIWNEICEFRIANPHFAMIRFEVQDEDMFGEPNFIGQAVFPLGSIRTGYRSVVLRNKYSE 1211

Query: 1185 ELELSTLMVHLSI 1197
            ELEL+TL+VH SI
Sbjct: 1212 ELELATLLVHTSI 1224


>UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep:
            Phospholipase C gamma - Chaetopterus pergamentaceus
          Length = 1322

 Score = 1272 bits (3150), Expect = 0.0
 Identities = 612/1196 (51%), Positives = 835/1196 (69%), Gaps = 40/1196 (3%)

Query: 20   LISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVR 79
            ++  +ERG    KF+P+KRPE+R   V+ ET Q++W R N   R   EG +D R++KEVR
Sbjct: 28   MLRLLERGCVFTKFYPKKRPEKRTFQVKLETRQLIWIR-NQGGRA--EGTVDFREIKEVR 84

Query: 80   TGKSSKDFER-WPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA 138
             G +S+DFE+  PE+ ++L+   CF + YG++F+L+  S  A + +E   W+ G+ +L+ 
Sbjct: 85   PGTNSRDFEKLMPEDARKLDPLLCFVVLYGSQFRLKTLSVAAVSPEEYNLWMTGLKFLVE 144

Query: 139  EAVSASYPLQIERWLRKEFYSIEN----SHEK-----ITLKEVKAFLPKINCKISTSKLR 189
               SA YPLQ+ERWL KEF  ++     S +K     +TLK++K++LP+IN KI  +KLR
Sbjct: 145  NTQSAPYPLQVERWLWKEFNMMDTRAGVSSQKDREITVTLKDIKSWLPRINLKIPNNKLR 204

Query: 190  DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY-SVYCSNGTTITLREFQNFL 248
            + +Q +DT  + +IGF  F++LY+ L++    V  +FD+Y   Y SNG  IT  +F NFL
Sbjct: 205  EKYQRIDTNCK-DIGFVAFSLLYRDLVY----VPTVFDRYFGGYMSNGENITAEDFLNFL 259

Query: 249  RDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308
            + E+ D   D      Q +  +L D  R +  P+FT  EF++ ++S++N+I++  +D VT
Sbjct: 260  KSEEKDTSVDTVRTVEQLMLQFLDDQMRAV-RPFFTPQEFMDWMFSEENTIWNKAFDAVT 318

Query: 309  QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
            QDM +PLS+YWI+SSHNTYLT +Q+SSESS EAY R L+ GCRCIELDCWDGPD  P IY
Sbjct: 319  QDMDQPLSYYWIASSHNTYLTENQYSSESSTEAYARVLQMGCRCIELDCWDGPDNLPHIY 378

Query: 369  HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
            HGHTLT+KIRFMDVL TIK +AF+ SEYP+ILSIE++CSL QQR MASAF++VFGD+LL+
Sbjct: 379  HGHTLTSKIRFMDVLYTIKANAFLVSEYPIILSIENHCSLLQQRNMASAFREVFGDMLLI 438

Query: 429  HPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVR----QEEGKDLDLRNSIKNGI 484
             P+D NET LPSP+             P+G + + + +          D DL NSIKN I
Sbjct: 439  EPIDVNETVLPSPNQLKRRIILKHKKLPDGVDGTDWRMAGLADDMSVADGDLSNSIKNDI 498

Query: 485  LHLEDPVDKEWKPHAFVLTENKLYYTE--SYNSQXXXXXXXXXXXXXXNAIVPQDELHFA 542
            L LEDP+DKEW PH FVLT++KL+YT+  +  SQ                +   DE+HF+
Sbjct: 499  LFLEDPIDKEWHPHFFVLTQSKLHYTDETAVTSQEDEEEESNDTSLQLEGL-GNDEMHFS 557

Query: 543  ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602
            E WFHGKL G R++AEDLL+ +++LGDGTFLVRES TFVGD+ LSFWR+  VNHCRI+ K
Sbjct: 558  EKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSK 617

Query: 603  QERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHC 662
            QERG TK+YLID++ FDSLY+LITHY+ +PLRSQ+F   LKEPVPQP  H GK W+H   
Sbjct: 618  QERGQTKYYLIDNLAFDSLYSLITHYQKYPLRSQDFQQILKEPVPQPQSHHGKPWYHEKL 677

Query: 663  TRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFE 722
             RT+AE++L++  +DGAFLVR +  +  S+AISFR E +IKHC +KQEGRL+TIG  +FE
Sbjct: 678  DRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLFTIGNAQFE 737

Query: 723  SLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFTSKVTV 781
            SL+ELV+YYE  PLY+K+KL +P++E+ V+ +  +PDD  +YG PG YM+P  FT K+ V
Sbjct: 738  SLVELVNYYEKKPLYRKMKLKHPVNEKFVQSVGEDPDDTAIYGGPGIYMNPNDFTPKIHV 797

Query: 782  KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPD 841
            +ALYDYRA+ +DELSFCK+AIITNV K DEGWW GD G ++  +FP+NYV EI      D
Sbjct: 798  RALYDYRAQMEDELSFCKNAIITNVIKRDEGWWLGDPGNQKRLYFPSNYVEEIR--SQDD 855

Query: 842  VTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATR 901
            V     ++S  LG++QKG ++V G  V+ ++ +G G   ++ R+Q  A   P ++AA T 
Sbjct: 856  V-----SDSMPLGNMQKGTINVTGCAVDRIL-NGKGDKAYVFRIQHTANERPLEIAAETE 909

Query: 902  ESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFV 961
            E  L+W                    +E+   IAKE SDLI+YCRSV F  E+       
Sbjct: 910  EKMLDWMKNIRACANLAEEKVKKKHMIEKNKGIAKEFSDLIVYCRSVPFEPEKAPGN--- 966

Query: 962  YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021
            Y +MSSFPETK E+ +++++    +KY+  QLSR+YPKG RIDSSNY+P PFWNCG  M+
Sbjct: 967  YYDMSSFPETKGEKSLNRKDAAILMKYNKYQLSRVYPKGSRIDSSNYDPQPFWNCGCHML 1026

Query: 1022 ALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI 1081
            ALNYQTPD+ MQ+N GKFK NG CG+IL+P+ M  + +NP +K+ +EG V+P+++ + +I
Sbjct: 1027 ALNYQTPDRSMQLNEGKFKLNGRCGYILQPECMHMDNFNPFNKRDLEGVVEPLSLSINII 1086

Query: 1082 GARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELA 1141
              RHL KTGRG ASPFVEVEI+GA+YD   K  T TV DNGLNP+WN+ C+F++ NPE+A
Sbjct: 1087 AGRHLVKTGRGIASPFVEVEIVGAEYDF-QKYKTSTVQDNGLNPVWNEQCDFDIINPEVA 1145

Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L+RFVVQD D+F +P+F+GQA FP+ CLR G+RSVPL N  SE+LEL++L+VH+ +
Sbjct: 1146 LLRFVVQDMDMFNDPHFMGQAVFPVKCLRSGFRSVPLKNGNSEDLELTSLLVHVEM 1201


>UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA -
            Drosophila melanogaster (Fruit fly)
          Length = 1236

 Score = 1150 bits (2848), Expect = 0.0
 Identities = 588/1250 (47%), Positives = 793/1250 (63%), Gaps = 79/1250 (6%)

Query: 5    CFNGAKDRLIHEADQLISYIERGSTVLKFFPR-KRPERRALCVRRETHQVLWSRI-NAPQ 62
            CF+     L+ E +Q I  +ERG+ V K + + +RP+RR L + RET Q+LW+ +     
Sbjct: 3    CFSAMSAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTP 62

Query: 63   RQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQT 122
            R  YEGA+ +R+++E+R GK SK+F  + ++ +R ESSKCF I +G  FKL+  S VA +
Sbjct: 63   RTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRFESSKCFVILHGNHFKLKSFSVVALS 122

Query: 123  DKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIEN-----------SHEKITLKE 171
            + E + WV+G+ Y++ + + A YPLQI+RWLR+E+Y IEN           S  ++T+K+
Sbjct: 123  EIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKD 182

Query: 172  VKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSV 231
             K FL  ++CK++T K  + F + D  ++ ++ FDDF+ LYQKL+   N    +     V
Sbjct: 183  FKLFLAGVSCKMTTGKFMEHFTE-DVRRKHDLKFDDFSRLYQKLLLP-NGFASVLSGSGV 240

Query: 232  ----YCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQRDIYEPYFTL 285
                Y  +   +   E + FL  EQ D    +   A+   FIRD+++D +RD+ EPY T 
Sbjct: 241  ANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTF 300

Query: 286  SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
             EFV+ L+SKQN +++S+YD+V  DM  PLS YWI+SSHNTYLTGDQFSSESS EAY R 
Sbjct: 301  PEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARA 360

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            LR GCRCIELDCW+GPD  P+I+HGHT+T+KI+FMDV++TIK+HAF +SEYP+ILSIE N
Sbjct: 361  LRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQN 420

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEG------- 458
            CSL QQR MA A  +VFGD+LL  P D+NE  LPSP+             P+        
Sbjct: 421  CSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGI 480

Query: 459  AEESSFAVRQE----------EGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLY 508
            +   S   R            E    ++R   K G+L+ +DPVDK W  + FVLT  +L 
Sbjct: 481  SSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELI 540

Query: 509  YT----ESYNSQXXXXXXXXXXXXXXNAIVPQ--------DELHFAECWFHGKLAGNRQE 556
            Y+    ES N                N+ + Q        DELHF E WFHGKL G R+E
Sbjct: 541  YSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKE 600

Query: 557  AEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSM 616
            A+DLL+ + H GDGTFLVRES TFVGDY LSFWR+ + NHCRIKLK E G  K+YL+++ 
Sbjct: 601  ADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENF 660

Query: 617  CFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNT 676
             FDSLY+LI +YR + LRS EF I LKEPVPQP KHE +EWFH + T+ QAE+ L +   
Sbjct: 661  VFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEI 720

Query: 677  DGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPL 736
             G+FLVRPS +   +F ISF   ++IKHCR+ QEGRLY I T+ FESL+ L++YY  +PL
Sbjct: 721  -GSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPL 779

Query: 737  YKKVKLWYPISEETVRRLVSEP---------DDNTVYGTPGYMDPTSFTSKVTVKALYDY 787
            Y+ VKL +P+S+E +R+ ++E          DDN   G   YM  ++    VT KALY Y
Sbjct: 780  YRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDN---GASNYMG-SNLEENVTCKALYSY 835

Query: 788  RARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLE 847
            +A + DELSF KHAIITNV + +  WW GDYGG      PANYV  I+   T D  S   
Sbjct: 836  KANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVID-STTEDYNS--L 892

Query: 848  NESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATRESALEW 907
            NE    G      +++ GA+  L   +  G   + +++Q+P M +PF +    +E+A EW
Sbjct: 893  NEEGTDGRTDS--IEIFGAVASLFESNDPGII-FKLQIQTPTMQNPFVIGFDNQETAYEW 949

Query: 908  XXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSS 967
                               K ERT R+AKE+SDLIIY RSV F     R   +++ EMSS
Sbjct: 950  IKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPF-----REHSWIFQEMSS 1004

Query: 968  FPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQT 1027
            FPETKAE+   QQ    F+ YH  Q+SR+YPKGQR+DSSN+NP+PFWN GSQM+ALNYQT
Sbjct: 1005 FPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQT 1064

Query: 1028 PDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLC 1087
             DK MQ+N  KF+ NG CG+ILKP FM  + +NP +    +G +  V V +R+I ARHL 
Sbjct: 1065 GDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNP-NNPLCDG-LSEVKVSIRLIAARHLF 1122

Query: 1088 KTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVV 1147
            + G+   +P + VE+IGA +D+GVK  TK V++NG NP+WN+ CEF V NP+ A++RF V
Sbjct: 1123 RGGKSN-NPQIVVELIGASFDTGVKYRTK-VNENGFNPVWNESCEFNVRNPQFAILRFEV 1180

Query: 1148 QDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            QDED+F E +FI QA +PL C+R+GYRSV L N FSEELELS+L++++ I
Sbjct: 1181 QDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKI 1230


>UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
            phosphodiesterase gamma-1; n=65; Eumetazoa|Rep:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            gamma-1 - Homo sapiens (Human)
          Length = 1290

 Score = 1141 bits (2826), Expect = 0.0
 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%)

Query: 3    SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58
            S C NG       +A+   L   +E G+ +  F+ +K  RPER+   V+ ET Q+ WSR 
Sbjct: 6    SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64

Query: 59   NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117
                    EGA+DIR++KE+R GK+S+DF+R+ E+   R + S CF I YG EF+L+  S
Sbjct: 65   ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121

Query: 118  FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176
              A ++ E   W+KG+ +L+ + + A  PLQIERWLRK+FYS++ N  ++I+ K++K  L
Sbjct: 122  LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181

Query: 177  PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234
             ++N ++   + LR+   D++ ++ G+I +  FA LY+ L++      D+ F + S   +
Sbjct: 182  SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240

Query: 235  NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
                    ++L EFQ FL D Q +    D +Q  +F+  +LRDP R+I EPYF L EFV 
Sbjct: 241  GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300

Query: 291  MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+SK+NS+++SQ D V  D M  PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G
Sbjct: 301  FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360

Query: 350  CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409
            CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ 
Sbjct: 361  CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420

Query: 410  QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467
            QQR MA  F+ V GD LL  P++ +   LPSP+              EG+  EE   ++ 
Sbjct: 421  QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480

Query: 468  QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527
              E    D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E  +S            
Sbjct: 481  YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532

Query: 528  XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581
                 +    ELH  E WFHGKL AG   R  AE LL  +    G  DG+FLVRES TFV
Sbjct: 533  EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592

Query: 582  GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641
            GDY LSFWR GKV HCRI  +Q+ G  KF+L D++ FDSLY+LITHY+  PLR  EF + 
Sbjct: 593  GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652

Query: 642  LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            L EPVPQ N HE KEW+HA  TR QAE +L +   DGAFLVR    E  S+AISFR E +
Sbjct: 653  LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711

Query: 702  IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760
            IKHCRV+QEG+   +G  +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++  +EPD 
Sbjct: 712  IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771

Query: 761  NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
              +Y    PG Y++     T K  VKAL+DY+A+++DEL+F K AII NV+K + GWWRG
Sbjct: 772  GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRG 831

Query: 817  DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875
            DYGGK+  WFP+NYV E+  P   +      +E++ LG L +GVLDV    + +   G  
Sbjct: 832  DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891

Query: 876  GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935
                 + + + S A +S  D+AA ++E   +W                    MER  +IA
Sbjct: 892  NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
             E+S+L++YCR V F+ E++  +   Y +MSSFPETKAE+ +++ +   F++Y+  QLSR
Sbjct: 951  LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055
            IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F     CG++L+P  M 
Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
            +E ++P DK S+ G ++P  + + V+GARHL K GRG   PFVE+E+ GA+YDS  K  T
Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128

Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            + V DNGLNP+W      F+++NPE A +RFVV +ED+F + NF+ QATFP+  L+ GYR
Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188

Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197
            +VPL N +SE+LEL++L++ + I
Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211


>UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|Rep:
            PLC-gammaS - Ephydatia fluviatilis
          Length = 1283

 Score = 1078 bits (2670), Expect = 0.0
 Identities = 562/1213 (46%), Positives = 758/1213 (62%), Gaps = 59/1213 (4%)

Query: 20   LISYIERGSTVLKFFPRKR-PERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEV 78
            ++  +ERG+ +++F  RKR PE++  C++ +T +V+   +    R   E ++DIR++KEV
Sbjct: 16   ILGALERGTVMVRFPARKRRPEKKLFCLKVDTFEVVQYPLTKGTRTVAEESIDIREIKEV 75

Query: 79   RTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA 138
            R G SSKDFER P+ETK+++   CF IY+GTEF+L   S  A    EC+AWVK + ++  
Sbjct: 76   REGVSSKDFERQPDETKKVDQYCCFVIYHGTEFRLTTLSVAALCRDECDAWVKALKHVTL 135

Query: 139  EAVSASYPLQIERWLRKEFYSIENSHEKITLK--EVKAFLPKINCKISTSKLRDVFQDVD 196
                AS+ L   RWL KEF ++E S + +T+   E+K ++ +I+ K   +K R +F D D
Sbjct: 136  AGNFASH-LLTHRWLNKEFLALEPSGDNLTIGPIELKKYVLRISSKALLNKARQLFIDFD 194

Query: 197  TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
              + G +G +DF  LY   I    +V+ I +++  +C++  ++T  E Q F R+EQ D  
Sbjct: 195  YSRAGRMGVEDFFNLYHNTI----HVKTIGERFYPFCADRQSLTFSEVQMFFREEQKDKR 250

Query: 257  GDDEVQASQFIRDYLRDPQRDIYEPYFT---LSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313
             DD V  +  IR+Y R P R + +P      L EFV  L+SKQNS++  +Y ++ QDM R
Sbjct: 251  ADDTVYLAGLIREYARVPNRTVRDPRLPSLLLPEFVNFLFSKQNSVFAEEYAQIYQDMDR 310

Query: 314  PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373
            P+SHYWI+SSHNTYLTG+Q+SSESS E Y R LR GCRCIELDCWDGPDG P IYHG TL
Sbjct: 311  PISHYWIASSHNTYLTGNQYSSESSCECYSRALRMGCRCIELDCWDGPDGNPIIYHGRTL 370

Query: 374  TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433
            T+KIRF+DV++TIK+HAF+TSEYP+ILSIE +C + QQR MA  F++VFGD LL   +D 
Sbjct: 371  TSKIRFIDVIKTIKDHAFVTSEYPIILSIEQHCDIQQQRIMARQFKEVFGDALLTELVDL 430

Query: 434  NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKD-------LDLRNSIKNGILH 486
            N T LPSP +             +G EE+S   + EE  +        DL NSI NG+L 
Sbjct: 431  NATRLPSP-NALKRKIIIKHKKLDGTEETSGNNKPEEAGEEEGVTFNSDLCNSILNGLLF 489

Query: 487  LEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWF 546
            ++DP+DK W  H FVLTE+KLY+T+    Q                 +P  E H  E WF
Sbjct: 490  MQDPIDKNWAKHYFVLTEDKLYFTD----QQEKDEDEADKTETNTETLPSTEQHLKEKWF 545

Query: 547  HGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERG 606
            HGKLAG R  AE LL  +  + +G FLVRES TF GDY LSF R GK NHCRI  K E G
Sbjct: 546  HGKLAGGRVAAEKLLTDYKDV-NGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKSEGG 604

Query: 607  VTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQ 666
             T+FYLID   FDS+Y LI HY+S+PL+S  F   L EPVPQ N H GK WFH + +R++
Sbjct: 605  KTRFYLIDQTLFDSIYELIMHYKSNPLKSPTFEQVLAEPVPQQNSHLGKAWFHENLSRSE 664

Query: 667  AEELLRKTNTDGAFLVRPSEKE----QGSFAISFRTEKEIKHCRVK-QEGRLYTIGTVKF 721
            AEE+L+K   DGAFL+RPSE+     Q ++AISFR E ++KHCR++  E   Y IG+  F
Sbjct: 665  AEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVDESGQYCIGSAIF 724

Query: 722  ESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTV 781
            +SL ELV YYE +PLY++++L Y I+E+ ++ L     D+  Y    Y       + +T 
Sbjct: 725  DSLTELVQYYEANPLYRRMRLKYAINEDLLKSLGEAESDDVYYHPIYYTFNEEKATPITC 784

Query: 782  KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPD 841
            KAL+DY A + DELSFCK A+ITNV+K   GWW+GD G K   WFPAN+V E++     +
Sbjct: 785  KALFDYTAVRPDELSFCKDAVITNVEKHGGGWWKGDCGNKNQKWFPANHVEEVQ---ADE 841

Query: 842  VTSGLENESAALGSLQKGVLDVLGAIVEL--VVGDGGGAARW--LVRVQSPAMYSPFDM- 896
            VT     E   LG+LQ+G +D+ G   E+  +  +   A +   +++ +S  +     M 
Sbjct: 842  VT-----EDRQLGNLQQGAIDISGCTTEIHHLSSNNLYALKIVPMLKAESTELEKENHMG 896

Query: 897  ---AAATRESALEWXXXXXXXXXXXXXXXXX-------XXKMERTWRIAKEISDLIIYCR 946
               AA + E  L W                          K E+  RIA E+SD+I YCR
Sbjct: 897  LMVAAQSLEEILRWQKAIDEARNKANSHALAQMEKEKERKKDEQKKRIAIEMSDIIAYCR 956

Query: 947  SVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQE--NTFFVKYHTTQLSRIYPKGQRID 1004
             V F+  ++   G  YN M SF ET+ E+++  +     F V  H T L+R+YPKGQR+D
Sbjct: 957  PVPFDENKMNDMGKYYN-MCSFVETRVEKIVHNKSLAAQFLVHAH-TYLNRVYPKGQRLD 1014

Query: 1005 SSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK 1064
            SSNY+PVP WN G QMV+LNYQT DK MQ+N GKF QNG CG++L    MFE G+NP D 
Sbjct: 1015 SSNYDPVPMWNGGCQMVSLNYQTGDKSMQLNEGKFLQNGKCGYVLMSDCMFEPGFNPLDI 1074

Query: 1065 KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLN 1124
             +   K  P+T+ +++IG RHL + GRG   P VEVE+IG + D   K  T T  +NG N
Sbjct: 1075 ST--QKTSPITLSVQIIGGRHLLRQGRGMTCPLVEVEVIGVEVDYN-KYRTSTCKENGFN 1131

Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184
            P+WN+ C+F++ NP LAL+RF V DED FG+ NF+GQA FP+LCLR GYRSVPL NAFSE
Sbjct: 1132 PVWNEGCDFDINNPALALLRFTVLDEDAFGDANFLGQAVFPVLCLRTGYRSVPLRNAFSE 1191

Query: 1185 ELELSTLMVHLSI 1197
            ELEL +L+VHL +
Sbjct: 1192 ELELCSLLVHLEM 1204


>UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio
            "Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep:
            Homolog of Brachydanio rerio "Phospholipase C gamma 1. -
            Takifugu rubripes
          Length = 1071

 Score =  812 bits (2008), Expect = 0.0
 Identities = 455/1023 (44%), Positives = 614/1023 (60%), Gaps = 71/1023 (6%)

Query: 24   IERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTG 81
            +E G+ +  F+ +K  RPERR   ++ +T  ++WSR   P +   EG +DI++++E+R G
Sbjct: 6    LEMGTVMTVFYQKKSQRPERRTFQIKPDTRLLVWSR--NPDKS--EGEIDIQEIRELRLG 61

Query: 82   KSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAV 141
            K S+DFER+PEE ++LE+++CF + YG EF+LR  S +A +++E   W+ G+ +++++  
Sbjct: 62   KCSRDFERYPEEARKLEAAQCFIVLYGQEFRLRTLS-LAASEEEVNMWI-GLTWMMSDTQ 119

Query: 142  SASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSK-LRDVFQDVDTEKR 200
             A  P Q                + +T+K+VKA LP+IN ++   + L+D  Q+V  E R
Sbjct: 120  RAPAPQQT---------------DSVTVKDVKALLPQINYRVPNMRFLKDKLQEV--EAR 162

Query: 201  GEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDE 260
             ++ F +FA LY+ L+FD        +  +V       I+L +FQ FL+ +Q ++   D 
Sbjct: 163  SDLTFPNFAQLYRTLMFDAQKNVSGSELLNVDRPELCQISLYDFQKFLQMDQKESWASDL 222

Query: 261  VQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYW 319
                 F+  Y+R  QR   EP   L EF+  L+SK+NSI D Q       DM RPLS YW
Sbjct: 223  SLVRDFLMGYMRGGQR--AEPMLQLDEFLTFLFSKENSICDPQRLTLAPDDMKRPLSQYW 280

Query: 320  ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRF 379
            ISSSHNTYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGPD  P IYHGHTLT+KI+F
Sbjct: 281  ISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKF 340

Query: 380  MDVLRTIKEHAFITSE-YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSL 438
            +DVL TIKEHAF+TSE YP+ILSIED+CS+ QQR MA+ F+ VFGDLLL  P+D +   L
Sbjct: 341  LDVLHTIKEHAFVTSERYPVILSIEDHCSVVQQRNMATHFRKVFGDLLLSKPVDNSAEEL 400

Query: 439  PSPHDXXXXXXXXXXXXPEGA--EESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDKEWK 496
            PSPH              EG   EE S A   E     DL NS+KNGIL+LEDP+D  W 
Sbjct: 401  PSPHQLRRKILIKHKKLVEGTLYEEVSSASYSEN----DLSNSLKNGILYLEDPIDHTWT 456

Query: 497  PHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAG---N 553
            PH FVLT NK+YY+E   SQ                    +E H AE WFHGKL G    
Sbjct: 457  PHYFVLTSNKIYYSEE-TSQYQTADQEEEDEVKEEC--NNNEQHCAERWFHGKLGGGRDG 513

Query: 554  RQEAEDLLRAHAHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFY 611
            RQ AE LL+ +   G  DGTFLVRES TFVGDY LSFWR G+V HCRI  +QE G T+FY
Sbjct: 514  RQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFY 573

Query: 612  LIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELL 671
            L D++ FDSLY L+ HYR  PLR  EF + L  PVPQPN HE +EW+H+  +R QAE +L
Sbjct: 574  LTDNLVFDSLYRLMCHYRDTPLRCNEFEMRLGSPVPQPNAHESREWYHSSLSRVQAEHML 633

Query: 672  RKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIG-TVKFESLIELVSY 730
             +   DGAFLVR    E  S+AISFR E +IKHCR++QEGRL+ +G + +FESL++LV+Y
Sbjct: 634  MRVPRDGAFLVR-KRSESHSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVNY 692

Query: 731  YENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRAR 790
            YE HPLY+K++L YPI+E+T+ R+ +        G      P  F + + V         
Sbjct: 693  YEKHPLYRKMRLRYPINEDTLDRMGTTVSQARPPGVSA-TTPDHFHTFMRVSLF----LH 747

Query: 791  QDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENES 850
            +D E+  C     T  D+   G  R           PA  V    + H   + S    E+
Sbjct: 748  EDSEVQICS----TMTDEHLGGCLR----------LPAATVPARFMTHCFLLLS-QSTEN 792

Query: 851  AALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS----PFDMAAATRESALE 906
            + LG+  KG +DV    V +V  +G  +  ++  V S    S      D++A + E    
Sbjct: 793  SPLGTFLKGFMDVSTCHV-VVHAEGKNSRPFVFTVHSQNFSSQPVQSLDVSADSLEELTH 851

Query: 907  WXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMS 966
            W                   +MER  +IA E+S+L++YCR V FN +++      Y +MS
Sbjct: 852  WVTKIREAAQNADARMQEEKQMERRKKIAVELSELVVYCRPVPFNEDKIGTDRACYKDMS 911

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026
            SFPETKAE+  ++     F++Y+  QLSR+YP+GQR+DSSNY+P+P W CGSQ+VALN+Q
Sbjct: 912  SFPETKAEKFTTRSRGKRFLQYNRRQLSRVYPRGQRLDSSNYDPLPMWLCGSQLVALNFQ 971

Query: 1027 TPD 1029
            TP+
Sbjct: 972  TPE 974



 Score =  103 bits (246), Expect = 4e-20
 Identities = 46/88 (52%), Positives = 64/88 (72%), Gaps = 1/88 (1%)

Query: 1112 KLVTKTVSDNGLNPLWNDI-CEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
            +L     +DNGLNP+W      F+V NP  + +RF V DED+F +PNF+ QATFP+  L+
Sbjct: 981  ELCVLLAADNGLNPVWVQTHFVFDVHNPTFSFLRFTVYDEDMFSDPNFLAQATFPVQLLQ 1040

Query: 1171 KGYRSVPLTNAFSEELELSTLMVHLSII 1198
             GYRSVPL N++SEELEL++L+VH+ I+
Sbjct: 1041 TGYRSVPLRNSYSEELELASLLVHVEIV 1068


>UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole
            genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF13726, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1377

 Score =  803 bits (1986), Expect = 0.0
 Identities = 464/1027 (45%), Positives = 606/1027 (59%), Gaps = 115/1027 (11%)

Query: 24   IERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTG 81
            +E G+ +  F+ +K  RPERR   VR +   ++WSR   P +   EG LDI+D++E+R G
Sbjct: 2    LETGTVMTLFYQKKSQRPERRTFQVRPDMRLLVWSR--NPDKP--EGELDIQDIRELRLG 57

Query: 82   KSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAV 141
            K S+DFER+PEE ++L+++ CF + YG EF+LR  S  A +++E   W+ G+ +L+ +  
Sbjct: 58   KGSRDFERYPEEARKLDAAHCFIVLYGQEFRLRTLSLAAFSEEEVNMWMTGLTWLMTDTQ 117

Query: 142  SASYPLQIERWLRKEFYSIENSHE------------------------KITLKEVKAFLP 177
             A  P Q +RWLRK+F  ++ +HE                         +T+K+VKA LP
Sbjct: 118  RAPAPQQTDRWLRKQFEVMDRNHEGRWVTLPEHVNIQSQQPVRDAPHSSVTVKDVKALLP 177

Query: 178  KINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNV---QDIFDKYS--V 231
            +IN ++   + L+D  Q+V  E R ++ + +FA LY+ L+FD        ++   ++   
Sbjct: 178  QINFRVPNMRFLKDKLQEV--EARSDLTYPNFAQLYRTLMFDSQKTVSGSELLSSWNSPS 235

Query: 232  YCSNGT--------TITLREFQNFLR--------DEQHD-----NLGDDEVQASQF--IR 268
             C   T        + T R F  + R        D +       +L   E  AS    +R
Sbjct: 236  LCGTSTDRNSARFPSTTSRSFCRWTRRYGDGLPLDSRRALLTSVSLSSQEPWASDLGRVR 295

Query: 269  DYLRDPQR--DIYEPYFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHN 325
            ++L    R     EP   L EF+  L+SK+NSI D Q    V  DM RPLS YWISSSHN
Sbjct: 296  EFLMGYLRGGQQAEPMLQLDEFLTFLFSKENSICDPQLLAVVPDDMKRPLSQYWISSSHN 355

Query: 326  TYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRT 385
            TYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGPD  P IYHGHTLT+KI+F+DVL T
Sbjct: 356  TYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKFLDVLHT 415

Query: 386  IKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXX 445
            IKEHAF+TSEYP+ILSIED+CS+ QQR MA+ F+ VFGDLLL  P+D N   LPSPH   
Sbjct: 416  IKEHAFVTSEYPVILSIEDHCSVVQQRNMATHFKKVFGDLLLTKPVDNNAEELPSPHQLR 475

Query: 446  XXXXXXXXXXPEGA--EESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLT 503
                       EG   EE S A   E     D+ NS+KNGIL LEDPVD  W PH FVLT
Sbjct: 476  RKILIKHKKLVEGTLYEEVSSASYSEN----DISNSLKNGILFLEDPVDHTWTPHYFVLT 531

Query: 504  ENKLYYT-ESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAG---NRQEAED 559
             NK+YY+ E+ + Q              N     +E H AE WFHGKL G    RQ AE 
Sbjct: 532  SNKIYYSEETSHYQTADEEEDDEVKEECN----NNEQHCAERWFHGKLGGGRDGRQVAEK 587

Query: 560  LLRAHAHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMC 617
            LL+ +   G  DGTFLVRES TFVGDY LSFWR G+V HCRI  +QE G T+FYL D++ 
Sbjct: 588  LLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFYLTDNLV 647

Query: 618  FDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTD 677
            FDSLY LI HYR  PLR  EF + L  PVPQPN HE +EW+H+  TR QAE +L +   D
Sbjct: 648  FDSLYRLICHYRDTPLRCNEFEMRLGNPVPQPNAHESREWYHSSLTRVQAEHMLMRVPRD 707

Query: 678  GAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIG-TVKFESLIELVSYYENHPL 736
            GAFLVR    E  S+AISFR E +IKHCR++QEGRL+ +G + +FESL++LVSYYE HPL
Sbjct: 708  GAFLVR-KRSEHNSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLMDLVSYYEKHPL 766

Query: 737  YKKVKLWYPISEETV--------------RRLV----------SEPDDNTVY--GTPG-Y 769
            Y+K+KL YPI+E+T+              RR V           E D   +Y   TP  Y
Sbjct: 767  YRKMKLRYPINEDTLDKMGTTVSRAPPERRRSVESQMMKPPVPQELDYGALYEVRTPHFY 826

Query: 770  MDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828
            ++     T++ TVKALYDYRA+++DEL F K A+I NVDK + GWWRGDYGGK+  WFPA
Sbjct: 827  VEANKMPTARCTVKALYDYRAQREDELCFSKQALILNVDKQEGGWWRGDYGGKKQLWFPA 886

Query: 829  NYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSP 888
            NYV E+      ++   + ++++ LG+  KG LDV    V +V  DG  +  ++  V S 
Sbjct: 887  NYVEELPSSPLRELDEAVSSKNSPLGTFLKGFLDVTSCHV-VVHKDGKNSRPYVFTVHSQ 945

Query: 889  AMYS----PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIY 944
               S      D++A + E  + W                   +MER  +IA E+SDL++Y
Sbjct: 946  HFSSQPVQSLDVSADSLEELIHWVTKIREAAQNADARMQEEKQMERRKKIAVELSDLVVY 1005

Query: 945  CRSVTFN 951
            CR V FN
Sbjct: 1006 CRPVPFN 1012



 Score =  130 bits (313), Expect = 3e-28
 Identities = 73/166 (43%), Positives = 97/166 (58%), Gaps = 25/166 (15%)

Query: 1029 DKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI------- 1081
            DKPMQ+N   F   GG G+I +P  M E+ ++P DK ++   V+P+T+ L+V+       
Sbjct: 1160 DKPMQLNQAFFLLGGGSGYIPQPDVMREDVFDPFDKDTLN--VEPITIQLQVLPNSQGCN 1217

Query: 1082 --------------GARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW 1127
                          GARHL K GR    PFVEVEI GADYDS  K  T  V+DNGLNP+W
Sbjct: 1218 QSESYPCPWPLQVLGARHLPKNGRSIVCPFVEVEICGADYDS-CKYKTDVVADNGLNPVW 1276

Query: 1128 -NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172
                  F++ NP  + +RF V DED+F +PNF+ QAT+P+  LR G
Sbjct: 1277 LQKQFVFDIHNPTFSFLRFTVYDEDMFSDPNFLAQATYPVQLLRTG 1322


>UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3; n=2;
            Caenorhabditis|Rep: Putative uncharacterized protein
            plc-3 - Caenorhabditis elegans
          Length = 1299

 Score =  700 bits (1730), Expect = 0.0
 Identities = 395/1058 (37%), Positives = 585/1058 (55%), Gaps = 59/1058 (5%)

Query: 167  ITLKEVKAFLP-KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI 225
            +  K +K F+   +  K+ + +L+ V +D       +  F    +++   +F  +   D+
Sbjct: 161  VARKHMKPFVQTSLQFKVQSDQLQQVTED--QMNSDQFSFASRQLIHVPELFS-SRFADL 217

Query: 226  FDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQR---DIYEPY 282
             +K+      G  +T + F  FL  +Q D L  +  +A +F+  Y ++ Q    D  EP 
Sbjct: 218  AEKHE---RKGLVVTFQNFLRFLDGKQFDELASNRTRALEFLNRYFQEDQAYFGDRNEPS 274

Query: 283  FTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342
             T+ EF + L+S++NS++D   +KVT DM+RPLSHYWI+SSHNTYLTGDQ  SESSL+ Y
Sbjct: 275  MTVFEFCDFLFSRENSLWDPTNEKVTHDMSRPLSHYWIASSHNTYLTGDQLRSESSLDCY 334

Query: 343  VRCLRSGCRCIELDCWDG---PDGTPFI----YHGHTLTTKIRFMDVLRTIKEHAFITSE 395
             + L  GCRCIELDCWDG   P    FI    YHG+T+T+KI   DVL  I+ +AF+TSE
Sbjct: 335  AQALLMGCRCIELDCWDGQKKPGSAEFIDIVIYHGYTMTSKILLRDVLHVIRHYAFVTSE 394

Query: 396  YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXX 455
            YP+ILSIEDNCS+P QR +A   +D+ GD LL  P ++ E  LPSP              
Sbjct: 395  YPVILSIEDNCSVPAQRLLAQELKDILGDYLLTQPANREEKQLPSPAALKKKIIVKHKKL 454

Query: 456  PEGAEESSFAVRQEEGKDLDL--RNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYT--- 510
            P  +E+ +  V+ +E +D ++  R  +K GIL +++    EW  H F+L  ++L Y    
Sbjct: 455  PIESEDLAAVVKTDEFQDTEIISRECVKKGILMVKNNNSHEWTSHVFILFPDRLCYLIQT 514

Query: 511  ---ESYNSQXXXXXXXXXXXXXXNAI--VPQDELHFAECWFHGKLAGNRQEAEDLLRAHA 565
               E+ N                 +   V  +E+H  E WFHG+    R EA+  +  H 
Sbjct: 515  ADPENPNDDTVSVSGDEEREEETPSGFGVKPEEMHVTEEWFHGRC--ERDEAKKRILEHK 572

Query: 566  HLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLI 625
              G+G F++R+S  F+GD+ LS    GKV+H RI+ K      K+Y +D+   D+LY L+
Sbjct: 573  EKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDKEKKYYFMDNKVCDTLYELV 632

Query: 626  THYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPS 685
            ++Y  H L +  F + L  P PQP  H  + WF A   + +AEELL     DGAFL+R S
Sbjct: 633  SYYTRHYLTTAHFKMVLTIPCPQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTS 692

Query: 686  EKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYP 745
              +   + +S + + E  H R+K++GR++ +    FE+L ++V +Y N    + + L +P
Sbjct: 693  STDSSVYVLSLKVDGEFWHYRLKRDGRIFVVNQKVFENLNQIVEFYANREFVRGISLRFP 752

Query: 746  ISEETVRRLVSEPDDNTVYGTPG-YMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIIT 804
            ++E+ +  L +E  +     TPG YMD      +V  +AL  YR   DDELSF  + IIT
Sbjct: 753  VNEKDISHLTAELAEAR---TPGCYMDLKDLDKEVQARALRPYRGTADDELSFPANVIIT 809

Query: 805  NVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVL 864
             V + +EG WRG YG     WFP+ +V EI     P+  S  E  +          +++ 
Sbjct: 810  -VLRKEEGLWRGRYGSLT-GWFPSAHVQEI----LPEKVSTSETSN-------YNTIELA 856

Query: 865  GAIVELV-VGDGGGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXX 923
            G ++E +   D     R     Q       + +AA++ E A  W                
Sbjct: 857  GTLIERIHDADRPNVIRISQSNQHWMNKQYYLLAASSSEEADGWQNNLFELTRSVNTKMS 916

Query: 924  XXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENT 983
                 E+  RIA E+S+L++YC++V F  +   I    + EM SF E K ++L+ +    
Sbjct: 917  ILRTKEKEKRIAAELSNLVVYCQAVPF--DPAHIYNDAFYEMCSFVEGKLDKLVEKG--- 971

Query: 984  FFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNG 1043
              + +++ +LSR+YP G RI S+NY+PVP WN G  MVALNYQT DKPMQ+N GKF  NG
Sbjct: 972  -LLPFNSRKLSRVYPNGSRITSNNYSPVPMWNAGCHMVALNYQTGDKPMQLNQGKFLANG 1030

Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK--TGRGTASPFVEVE 1101
             CG++LKP +M  + ++P + +       P+ + ++VIG RHL +    +G  SPFVE+E
Sbjct: 1031 RCGYLLKPDYMLTDDFDPTNTEKF-ATAYPIRLNVQVIGGRHLSRKDKNKGICSPFVEIE 1089

Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN--FI 1159
            IIG   D+ V   TKT++ NGLNP+WN    FE+  PE+ALIRF V+D D  G     FI
Sbjct: 1090 IIGMPCDTKV-FQTKTIASNGLNPIWNQTFTFEIQCPEVALIRFHVEDGDFVGPKTDPFI 1148

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQA FP+  +R G+RSVPL N +SEELELS+L+V + +
Sbjct: 1149 GQAVFPVDSIRCGFRSVPLKNQYSEELELSSLLVDVQM 1186


>UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome
           shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13
           SCAF14566, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1249

 Score =  654 bits (1617), Expect = 0.0
 Identities = 353/863 (40%), Positives = 516/863 (59%), Gaps = 57/863 (6%)

Query: 24  IERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKS 83
           +E G+ +  F  R++ ER  + V  ET QV W+R         +G LD+ +++E+R G++
Sbjct: 13  LEMGAVMTVF--RQKAERLTVQVIMETRQVAWTRT----ADKTDGVLDLFEIREIRPGRN 66

Query: 84  SKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVSA 143
           SKDFER+ +   + + + CFTI+YG++F L   S    +  E + W+ G+  L  E + A
Sbjct: 67  SKDFERFRDGKDKHDENACFTIFYGSQFVLNTLSLGVDSVTEAQKWLTGLELLWKETLEA 126

Query: 144 SYPLQIERWLRKEFYSIENSH-EKITLKEVKAFLPKINCKISTSK-LRDVFQDVDTEKRG 201
             P+ IE WLRK+ YS+  +    IT+KE+K  LP +N K   ++ L+D FQ+V + K+ 
Sbjct: 127 PTPVLIESWLRKQMYSVNQTKTNSITVKELKTLLPLLNYKAPGARALKDKFQEVGS-KKD 185

Query: 202 EIGFDDFAVLYQKLIFDENNV---QDIFDKYSV-YCS---------NGTTITLREFQNFL 248
            + F+ F  LY  ++F++N     Q I +++    C+         + + + L +FQ FL
Sbjct: 186 RLDFEQFHKLYNHIMFEQNEASLKQTILNEFKKDSCAFILGNTDKPDASAVMLHDFQRFL 245

Query: 249 RDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308
             +Q +    D  Q  + +  ++ D      +P FT+SEF+  L+S++NSI+D +  +++
Sbjct: 246 VYDQKECWAADLNQVRELMTIFIDDTMSKTNDPVFTVSEFLGYLFSEENSIWDKKVSEIS 305

Query: 309 -QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFI 367
             DM  PLSHYWI+SSHNTYLTGDQ  SESS EAYVR LR GCRC+ELDCW+GP G P I
Sbjct: 306 CMDMNNPLSHYWINSSHNTYLTGDQLRSESSTEAYVRALRLGCRCVELDCWEGP-GEPII 364

Query: 368 YHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL 427
           YHG T TTKI+F DV++ I +HAF+TSE+P+ILSIE++C + QQR+MA  F+DVFGD LL
Sbjct: 365 YHGWTRTTKIKFEDVVKAINDHAFVTSEFPVILSIEEHCPIEQQRQMARIFRDVFGDKLL 424

Query: 428 VHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIKNGILHL 487
             P+++    LPSP                  +    +V +  G   DLR   K G L +
Sbjct: 425 SEPVEQVAEQLPSPTQLKGKII---------LKHKKLSV-EGGGTAKDLRKGQKQGDLQI 474

Query: 488 EDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFH 547
            DPVDK+W  H  V++++ LYY E    +                   Q +LH  E WFH
Sbjct: 475 WDPVDKQWNKHYCVISDDNLYYAEEEEQEEEDT---------------QKDLHCTEPWFH 519

Query: 548 GKLAGNRQEAEDLLRAH-AHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           G +   RQ AE L+  + A  G  DGTFLVR S   V  Y LSFWR G+V HCR+++  +
Sbjct: 520 GHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWRNGRVQHCRVRVGNQ 579

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTR 664
            G   ++L  ++ F SL +LI HYR +PLR Q+F + L + VPQP+ H  + WF++  +R
Sbjct: 580 GGRPYYFLTANLHFPSLISLIQHYRENPLRCQDFELRLTDAVPQPSPHLNEGWFYSDLSR 639

Query: 665 TQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVK-FES 723
            QAE+ L +   DGAFL+R  E E  SFAI+F+ + ++KHCR+++EG  Y +GT   FES
Sbjct: 640 GQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLLGTTTYFES 699

Query: 724 LIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTS---KVT 780
           L+ELVSY+ N PLY+K+KL YP++ E V R     +  ++Y    Y++P    S   K  
Sbjct: 700 LVELVSYFRNRPLYRKIKLRYPVTPELVERFSMGKECASLYSMKMYVEPNEIESALPKNA 759

Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTP 840
           V+ALY Y+A + DELSF K A+I NV K  + WW+GDYGGK   +FPAN+V E+     P
Sbjct: 760 VRALYCYQATRPDELSFNKGALIYNVSKETDDWWKGDYGGKVQFFFPANHVEEVSRGGGP 819

Query: 841 DVTSGLENESAALGSLQKGVLDV 863
           ++T  + +++  LG L KGV+D+
Sbjct: 820 ELTQQVMDDN-PLGELCKGVVDI 841



 Score =  244 bits (596), Expect = 2e-62
 Identities = 134/314 (42%), Positives = 185/314 (58%), Gaps = 18/314 (5%)

Query: 894  FDMAAATRESALEWXXXX---XXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTF 950
            FD++A T E   EW                      ++E+   +A E+SDL++YC+  + 
Sbjct: 894  FDLSAETLEELFEWYQAAWDITQRKISKEYNRQHEVEVEKKEEVAMEMSDLVVYCQPRSK 953

Query: 951  NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNP 1010
              E+ R   + Y E+ SF E K       +E   F+ Y+   LSRIYPKGQR++SSNY+P
Sbjct: 954  --EKDRFDSYTYKEIRSFVENKVPGKNRTKE---FLLYNRKALSRIYPKGQRVESSNYDP 1008

Query: 1011 VPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGK 1070
             P W  G QMVALN+QT DK  Q+N   F  NGG G++L+P+ M  + ++P  +K+   +
Sbjct: 1009 YPLWAVGCQMVALNFQTADKYTQLNSALFSLNGGTGYVLQPEVMRSDVFDPLQEKN---R 1065

Query: 1071 VKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI 1130
            V    + +R+I ARHL K GR  ASPFVEVE+ G    +  K  T    DNGLNP+W   
Sbjct: 1066 VM-YMMDVRIIAARHLPKPGRSIASPFVEVELCG---HTDEKFKTAVYRDNGLNPVWKAP 1121

Query: 1131 CE---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELE 1187
             E   F V   ELA +RFVV +ED+F +PNF+ QATFP+  +R GYRSVP+ N +SE LE
Sbjct: 1122 AEPMTFTVHEHELAFLRFVVYEEDMFSDPNFLAQATFPVQGIRSGYRSVPMRNGYSERLE 1181

Query: 1188 LSTLMVHLSIITDG 1201
            L++L+VH+ I T G
Sbjct: 1182 LASLLVHIDIKTAG 1195


>UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 9 SCAF8684, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 966

 Score =  357 bits (877), Expect = 1e-96
 Identities = 181/335 (54%), Positives = 233/335 (69%), Gaps = 13/335 (3%)

Query: 540 HFAECWFHGKL-AGN--RQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGK 593
           H  E WFHGKL AG   RQ AE LL  +    G  DG+FLVRES TFVGDY LSFWR G+
Sbjct: 624 HVTEKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWRSGR 683

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
           V HCRI  +QE G  KFYL D++ FD+L+ LI HY+   LR  EF + L EPVPQ N HE
Sbjct: 684 VQHCRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQQVALRCNEFEMKLTEPVPQTNAHE 743

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
            KEW+HA+ +R+QAE +L +   DGAFLVR    E  SFAISFR E +IKHCRV+QEG+ 
Sbjct: 744 SKEWYHANLSRSQAENMLMRVPRDGAFLVR-KRAEPNSFAISFRAEGKIKHCRVQQEGQT 802

Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDDNTVY--GTPG-Y 769
             +GT +F+SL++L+SYYE HPLY+K+KL YPI+E+T+ ++  +EPD  ++Y    PG Y
Sbjct: 803 VVLGTSEFDSLVDLISYYEKHPLYRKMKLRYPINEDTLEKIGTAEPDYGSLYEGRNPGFY 862

Query: 770 MDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828
           ++     T K TV+A+Y+Y+A++DDELSF K+AII NVDK + GWW+GD GGK+  WFPA
Sbjct: 863 VEANQMPTFKCTVRAMYEYKAQRDDELSFTKNAIIYNVDKQEGGWWKGDCGGKKQLWFPA 922

Query: 829 NYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDV 863
           NYV EI  P   +       E++ LG L +G +DV
Sbjct: 923 NYVEEIS-PSAAEPDRAEMTENSPLGDLLRGSVDV 956



 Score =  272 bits (667), Expect = 4e-71
 Identities = 122/185 (65%), Positives = 147/185 (79%), Gaps = 1/185 (0%)

Query: 259 DEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQD-MTRPLSH 317
           D     +F+  YL+DP R++ +PYF   EF+  ++SK+N+I+DS  D+V  + M  PLSH
Sbjct: 279 DTNTVQEFMFSYLKDPLREVEQPYFHQDEFLTYMFSKENTIWDSSRDQVCPEKMNDPLSH 338

Query: 318 YWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKI 377
           YWISSSHNTYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGP+G P IYHGHTLTTKI
Sbjct: 339 YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPEGMPVIYHGHTLTTKI 398

Query: 378 RFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS 437
           +F DVL TIKEHAF+TS+YP+ILSIED+CS+ QQR MAS F+ VFGD+LL  P+D     
Sbjct: 399 KFSDVLMTIKEHAFVTSDYPIILSIEDHCSIVQQRNMASHFKKVFGDMLLTKPVDIAADG 458

Query: 438 LPSPH 442
           LPSP+
Sbjct: 459 LPSPN 463



 Score =  146 bits (354), Expect = 3e-33
 Identities = 70/172 (40%), Positives = 114/172 (66%), Gaps = 8/172 (4%)

Query: 16  EADQLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
           E + L   +E G+ +  F+ +K  RPERR   V+ ET  ++W+R         EG +DIR
Sbjct: 21  EMNNLYRDLELGTVLTLFYSKKSQRPERRTFQVKLETRTIIWTR----GTDKIEGEIDIR 76

Query: 74  DVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKG 132
           ++KE+R G+ S+DFER  E++  RL+ + CF I YGTEF+L+  S  A +D+E   WVKG
Sbjct: 77  EIKEIRPGQKSRDFERCLEDSAARLDQAHCFVILYGTEFRLKSLSLAATSDEEMTMWVKG 136

Query: 133 VLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKI 183
           + +L+A+ + +  PLQIERWLRK+FY+++ N  ++I+ K++K+ L ++N ++
Sbjct: 137 LNWLVADTLKSPTPLQIERWLRKQFYAVDRNREDRISCKDLKSMLSQVNYRV 188



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 55/180 (30%), Positives = 84/180 (46%), Gaps = 14/180 (7%)

Query: 458 GAEESSFAVRQEEGKDLDLRNSI-KNG-ILHLEDPVDKEWKPHAFVLTENKLYYT--ESY 513
           GA + SF VR+ E    D   S  ++G + H      +E     F LT+N ++ T     
Sbjct: 656 GAPDGSFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQEAGSPKFYLTDNLVFDTLFALI 715

Query: 514 NSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFL 573
           N                   VPQ   H ++ W+H  L  +R +AE++L       DG FL
Sbjct: 716 NHYQQVALRCNEFEMKLTEPVPQTNAHESKEWYHANL--SRSQAENMLMRVPR--DGAFL 771

Query: 574 VRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
           VR+       + +SF  +GK+ HCR+   Q+ G T   ++ +  FDSL +LI++Y  HPL
Sbjct: 772 VRKRAE-PNSFAISFRAEGKIKHCRV---QQEGQT--VVLGTSEFDSLVDLISYYEKHPL 825



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 26/41 (63%), Positives = 34/41 (82%)

Query: 475 DLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNS 515
           D+ NSIKNGIL+LEDP++ EW PH FVLT +K+YY+E  +S
Sbjct: 523 DISNSIKNGILYLEDPINHEWYPHFFVLTSSKIYYSEETSS 563


>UniRef50_UPI0000E493A1 Cluster: PREDICTED: similar to phospholipase
           C-gamma; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to phospholipase C-gamma -
           Strongylocentrotus purpuratus
          Length = 409

 Score =  266 bits (652), Expect = 2e-69
 Identities = 124/239 (51%), Positives = 165/239 (69%), Gaps = 8/239 (3%)

Query: 161 ENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDEN 220
           +N  + ++L+++K+FLP+IN K++T +LR+VF + D   R EI FD    LY  L+F   
Sbjct: 3   KNKTDTVSLRDMKSFLPRINLKMNTKELREVFNEADRWGRQEIPFDGLLQLYNNLVFQ-- 60

Query: 221 NVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYE 280
             Q++ D+   Y ++   +TL ++  FL  EQ D + ++  +  Q+IR Y  D  +   E
Sbjct: 61  --QEVADRLREYYNDMNRVTLNDYIRFLAQEQKDPVANNPHEVKQYIRKYFADSGKAAME 118

Query: 281 P----YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSE 336
                 FT+ EFV+ LYSK N I++  YD +T DM RPL  YWI+SSHNTYLTGDQ SSE
Sbjct: 119 SDSDLSFTVQEFVDYLYSKDNEIWNRFYDNITDDMERPLCDYWIASSHNTYLTGDQVSSE 178

Query: 337 SSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           SS+EAY RCLR GCRC+ELDCWDGPDG P IYHGHTLTTKIRF DVL+TIKEHA+IT++
Sbjct: 179 SSVEAYARCLRMGCRCLELDCWDGPDGLPIIYHGHTLTTKIRFYDVLKTIKEHAWITTD 237



 Score =  125 bits (301), Expect = 8e-27
 Identities = 56/91 (61%), Positives = 69/91 (75%), Gaps = 4/91 (4%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837
           KVTVKALYDY+A+++DELSFCKHAIITNVDK D GWW+GDYGGK++ WFP+NYV E+  P
Sbjct: 321 KVTVKALYDYKAQREDELSFCKHAIITNVDKQDHGWWKGDYGGKKNMWFPSNYVEEVTTP 380

Query: 838 HTPDVTSGLENESAALGSLQKGVLDVLGAIV 868
              D   G    +  LG+LQKG +D+ G  V
Sbjct: 381 ANND--QG--QNATLLGNLQKGAVDITGCSV 407


>UniRef50_A7RPT6 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 877

 Score =  258 bits (633), Expect = 5e-67
 Identities = 148/439 (33%), Positives = 243/439 (55%), Gaps = 24/439 (5%)

Query: 14  IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
           +   D+ I+ + RGS ++K     +   R   +  E   + W+    P ++G    + + 
Sbjct: 10  VFTVDESIALMRRGSELIKLRSASKKYPRTYFLDSELANISWT----PSKKGDRAKIPVN 65

Query: 74  DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
            VKE+R G  S  F +  E        +CFT+ +G  F       VA   +E   W+ G+
Sbjct: 66  TVKEIREGTVSDAFSQCSEV---FPEERCFTLIHGESFAT--LDLVAANREEAMHWMIGL 120

Query: 134 LYLIAEAVSASYPLQIER----WLRKEFYSIENSHEKI-TLKEVKAFLPKINCKISTSKL 188
            YL+A+    + P + ++    WLR  + + + S + + ++ EV   + K+N KIS  ++
Sbjct: 121 RYLMAQHYGENEPTRRQKARDLWLRGIYTAADKSGDGLLSIDEVYFLMHKLNVKISNRQV 180

Query: 189 RDVFQDVDTE---KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245
           R+ F+  DT+     G + F++FA  Y+ +    +  ++++     Y ++   +T++E  
Sbjct: 181 RENFKAADTDTVNSSGLLDFEEFANFYKSI----STRRELYMLLLKYGNSKENMTVQELL 236

Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYD 305
           NFLR EQ     D+E   S  I+ Y      +       +  F   L S    I++ ++ 
Sbjct: 237 NFLRIEQRVTECDEEY-CSNIIQTY-EPADSNKKNMLLGIDGFTSYLLSADGEIFNPEHS 294

Query: 306 KVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365
            V QDMTRPLSHY+I+SSHNTYLTGDQ +S SS++ YVR L+SGCRC+ELDCWDG DG P
Sbjct: 295 DVYQDMTRPLSHYFIASSHNTYLTGDQLASASSMDMYVRVLQSGCRCLELDCWDGKDGEP 354

Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425
            +YHG+T+T+K++F  V+  I + AF+ + YP+ILS+E++CS+ QQ+ MA+  +D F D+
Sbjct: 355 VVYHGYTMTSKVKFRYVILNINDFAFLNNRYPVILSLENHCSVEQQKFMANFMRDTFKDI 414

Query: 426 L-LVHPMDKNETSLPSPHD 443
           L ++  M  +   LPSP +
Sbjct: 415 LCILFFMLFDGKDLPSPQE 433



 Score =  204 bits (498), Expect = 1e-50
 Identities = 119/279 (42%), Positives = 166/279 (59%), Gaps = 18/279 (6%)

Query: 929  ERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKY 988
            +RT R+++ +SDL+ Y +S  F    +   G  + E+ S PE +A R  +  + T F +Y
Sbjct: 598  KRTIRLSRHLSDLVAYTQSRAFKGLEVEEDGENHWEVISIPEPRAYRF-TDTKATQFTRY 656

Query: 989  HTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFI 1048
               +L RIYP G RIDSSN NP  FWNCG Q+VALNYQT  + +Q+N GKF+ NG CG++
Sbjct: 657  TRYKLCRIYPAGYRIDSSNPNPQTFWNCGCQLVALNYQTEGRMLQINRGKFRANGNCGYV 716

Query: 1049 LKPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            LKP  + +E   ++P  +K I G  K V + +RVI  + L K        RG    P+VE
Sbjct: 717  LKPDILCKESQSFDPMTRKDIPGVSKKV-LKIRVISGQQLPKPKDSILGDRGEIIDPYVE 775

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D+  K  TKTV DNG NP+W +   F +  P++AL+RFVV DED  G  +FI
Sbjct: 776  VEIIGIPADTS-KYRTKTVIDNGFNPVWEETMVFLLNFPDIALVRFVVWDEDPIGR-DFI 833

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
            GQ T P   +  G+R V L     E L+ +T+  H++I+
Sbjct: 834  GQMTLPFQSIMPGFRHVHL-----EGLDQATVFCHVTIM 867


>UniRef50_Q3LUA8 Cluster: Phospholipase C-eta2; n=23;
           Euteleostomi|Rep: Phospholipase C-eta2 - Homo sapiens
           (Human)
          Length = 1416

 Score =  248 bits (607), Expect = 7e-64
 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  ++EV  G+ S+ F+R+P+ +   + + CF+IY+G+  +      V+
Sbjct: 82  PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 137

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
            + +    WV G+ YL+A    E   A      ++WL++ F   + N    +++ EV   
Sbjct: 138 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 197

Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           L K+N  +   +++ +F++ DT+  +G +GF++F   Y+ +    +  +D++     Y +
Sbjct: 198 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 253

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294
           +   +     Q FL+ EQ   +    +++ Q I +       +  +    +  F     S
Sbjct: 254 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 311

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
               I++ ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E
Sbjct: 312 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 371

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M
Sbjct: 372 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 431

Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           A    D+ GD L L     ++ T+LPSP
Sbjct: 432 AQYLTDILGDKLDLSSVSSEDATTLPSP 459



 Score =  204 bits (498), Expect = 1e-50
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 615  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 670

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 671  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 730

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 731  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 789

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 790  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 847

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 848  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 881


>UniRef50_O75038 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase eta-2; n=27; Euteleostomi|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase eta-2 - Homo sapiens (Human)
          Length = 1182

 Score =  248 bits (607), Expect = 7e-64
 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  ++EV  G+ S+ F+R+P+ +   + + CF+IY+G+  +      V+
Sbjct: 108 PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 163

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
            + +    WV G+ YL+A    E   A      ++WL++ F   + N    +++ EV   
Sbjct: 164 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 223

Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           L K+N  +   +++ +F++ DT+  +G +GF++F   Y+ +    +  +D++     Y +
Sbjct: 224 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 279

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294
           +   +     Q FL+ EQ   +    +++ Q I +       +  +    +  F     S
Sbjct: 280 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 337

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
               I++ ++  V QDMT+PLSHY+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E
Sbjct: 338 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 397

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M
Sbjct: 398 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 457

Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           A    D+ GD L L     ++ T+LPSP
Sbjct: 458 AQYLTDILGDKLDLSSVSSEDATTLPSP 485



 Score =  204 bits (498), Expect = 1e-50
 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 641  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 696

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            ++++  QLSRIYP   R+DSSNYNP PFWN G QMVALNYQ+  + +Q+N  KF  NGGC
Sbjct: 697  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 756

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G++LKP  M +  +NP  +  + G++K   ++LR+I  + L K        RG    PFV
Sbjct: 757  GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 815

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +F
Sbjct: 816  EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 873

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            IGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 874  IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 907


>UniRef50_Q4KWH8 Cluster: Phospholipase C eta 1; n=45;
           Tetrapoda|Rep: Phospholipase C eta 1 - Homo sapiens
           (Human)
          Length = 1693

 Score =  244 bits (597), Expect = 1e-62
 Identities = 132/389 (33%), Positives = 217/389 (55%), Gaps = 19/389 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  + +V  G+ S+ F R  E     + S CFTIY+G    +     + 
Sbjct: 55  PSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGN--FDPSCCFTIYHGNH--MESLDLIT 110

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
              +E   W+ G+ YL+A    E   A      ++W+++ F   + N    + ++E+   
Sbjct: 111 SNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQL 170

Query: 176 LPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           + K+N  +   K+R +FQ+ DT E +G + F++F V Y+ +       +D++     Y  
Sbjct: 171 MHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLR----RDLYLLLLSYSD 226

Query: 235 NGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293
               +T+ E   FL+ EQ  +N+  D       I+ +    +  + +    +  F   + 
Sbjct: 227 KKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTNFMR 283

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S    I++  + +V QDM +PL +Y+I+SSHNTYLTGDQ  S+S ++ Y R L+ GCRC+
Sbjct: 284 SPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCV 343

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ QQR+
Sbjct: 344 EVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRK 403

Query: 414 MASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           +A   + +FGD L +  +D  E   LPSP
Sbjct: 404 IAQYLKGIFGDKLDLSSVDTGECKQLPSP 432



 Score =  196 bits (479), Expect = 2e-48
 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 590  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 646

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 647  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 705

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 706  YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 764

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  PE+AL+RF+V D D  G  +F+
Sbjct: 765  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 822

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 823  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 855


>UniRef50_UPI000069FB22 Cluster:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide
           phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2)
           (Phosphoinositide phospholipase C-like 4) (Phospholipase
           C-like 4); n=2; Xenopus tropicalis|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide
           phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2)
           (Phosphoinositide phospholipase C-like 4) (Phospholipase
           C-like 4) - Xenopus tropicalis
          Length = 697

 Score =  242 bits (592), Expect = 5e-62
 Identities = 125/373 (33%), Positives = 216/373 (57%), Gaps = 13/373 (3%)

Query: 72  IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVK 131
           I  ++EV  GK S+ F+R+ + +   + + CF+IYYG    +     V+ + +E   W+ 
Sbjct: 2   IDSIQEVCEGKQSEIFQRYADGS--FDPNCCFSIYYGDH--MESLDLVSSSGEEARTWIT 57

Query: 132 GVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRD 190
           G+ YL+A     SY    + WL++ F   + N    +++ EV   + K+N  +   K++ 
Sbjct: 58  GLKYLMAGISDESYTCSYQIWLKQTFDEADKNGDGCLSINEVLQLMHKLNVNLPRQKVKQ 117

Query: 191 VFQDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249
           +F++ DT+  +G +GFD+F   Y+ +    +  +D++     Y ++   +   + + FL 
Sbjct: 118 MFKEADTDDNQGTLGFDEFCAFYKMM----STRRDLYLLMLTYSNHKDHLDPDDLKRFLE 173

Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ 309
            EQ   +   +      +  +   P+    +    +  F   + S    I++  + +V Q
Sbjct: 174 VEQK-MINVTKEYCLDIVDKFEPCPENK-KQGALGIDGFTNYMRSPAGDIFNPDHYQVNQ 231

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH 369
           DMT PLS+Y+I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E+DCWDGPDG P ++H
Sbjct: 232 DMTLPLSNYFIASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHH 291

Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LV 428
           G+TLT+KI F DV+ TI ++AFI ++YP+ILSIE++CS+ QQ++MA    ++ G+ L L 
Sbjct: 292 GYTLTSKILFKDVIETINKYAFIRNDYPVILSIENHCSVVQQKKMAQYLIEILGEKLNLS 351

Query: 429 HPMDKNETSLPSP 441
             ++++ T LPSP
Sbjct: 352 DVVNEDSTKLPSP 364



 Score =  185 bits (451), Expect = 6e-45
 Identities = 105/269 (39%), Positives = 156/269 (57%), Gaps = 18/269 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            + ++T ++++ +SDL+ Y +SV  +            ++SSF ETKA +++ QQ+   FV
Sbjct: 411  RQKKTMKLSRALSDLVKYTKSVGIHDVETESNW----QVSSFSETKAHQIL-QQKPAQFV 465

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +++  QLSRIYP   R+DSSNYNP PFWN G Q VALNYQ+  + +Q+N  KF  NG CG
Sbjct: 466  RFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQSVALNYQSEGRMLQLNRAKFNSNGNCG 525

Query: 1047 FILKPQFMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASP 1096
            ++LKP+ M +     +NP  +  + G++K   ++LR+I  + L K        RG    P
Sbjct: 526  YVLKPKCMCQVIVGAFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPKDSMLGDRGEIIDP 584

Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156
            FVEVE+IG   D   K  T+ V DNG NP+W +   F V  PE++LIRF+V D D  G  
Sbjct: 585  FVEVELIGLPVDC-FKEQTRVVDDNGFNPMWEETLVFTVHMPEISLIRFLVWDHDPIGR- 642

Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185
            +FIGQ T     +  G +   +   F ++
Sbjct: 643  DFIGQRTLSFSSMMPGKKRAHVNVQFHKQ 671


>UniRef50_UPI0000F1F4FE Cluster: PREDICTED: similar to phospholipase
           C-like 3; n=3; Danio rerio|Rep: PREDICTED: similar to
           phospholipase C-like 3 - Danio rerio
          Length = 1715

 Score =  238 bits (583), Expect = 6e-61
 Identities = 138/437 (31%), Positives = 226/437 (51%), Gaps = 24/437 (5%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P R+  +  + I  + +V  G+ S  F R  E +   + S CFTIY+G    +     V 
Sbjct: 37  PSRKSEKAKITIDSLYKVTEGRQSDIFHRHAEGS--FDPSCCFTIYHGNH--MESLDLVT 92

Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175
              +E   WV G+ YL+A    E   A      ++W+++ F   + N    + ++E+   
Sbjct: 93  SNSEEARTWVTGLRYLMAGISDEDSLAKRQRTHDQWMKQTFEEADKNGDGLLNMEEIYQL 152

Query: 176 LPKINCKISTSKLRDVFQDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           L K+N  +   K++ +FQ+ DT+ ++G + F++F V Y+ +       +D+F     +  
Sbjct: 153 LHKMNVNLPRRKVKQMFQEADTDDQQGTLTFEEFTVFYKMMSLR----RDLFLLLMCFSD 208

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294
               +T  E  NFLR EQ   +     +    I +     + +       +  F   + S
Sbjct: 209 KKDHLTAEELGNFLRVEQ--KMSSVTPECCLDIINKFEVSEENKQNGVLGIEGFTNYMRS 266

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
               +++ Q+ ++ QDM +P+ +Y+I+SSHNTYLTGDQ  S S  + Y   L++GCRC+E
Sbjct: 267 PACDVFNPQHHEINQDMDQPICNYFIASSHNTYLTGDQLLSHSKTDMYAWVLQAGCRCVE 326

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           +DCWDGPDG P + HG+TLT+KI F  V+ TI ++AF+ +E+P+ILSIE++CS+ QQ+++
Sbjct: 327 VDCWDGPDGEPMVQHGYTLTSKITFKSVIETINKYAFVNNEFPVILSIENHCSIQQQKKI 386

Query: 415 ASAFQDVFGDLLLV-HPMDKNETSLPSPHDXXXXXXXXXXXXP-------EGAEESSFAV 466
           A   +++FGD L V   ++K+   LPSP+             P       E  E S    
Sbjct: 387 AQHLKEIFGDKLDVGEALNKDPKQLPSPNLLKGKILLKGKRLPSYLSADAEEGEVSDDDS 446

Query: 467 RQEEGKDLDLRNSIKNG 483
             E   D  L+NS  NG
Sbjct: 447 ADEIEDDFKLKNSTSNG 463



 Score =  180 bits (439), Expect = 2e-43
 Identities = 103/278 (37%), Positives = 157/278 (56%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++++++SDL+++  SV    +    +G   N +S F E +A+ L+  +   F  
Sbjct: 567  RRRKTIKLSRDLSDLVVFTNSVAS--QECLDEGSPCNVLS-FSEARAQNLVHHRAERFLT 623

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             ++  QLSRIYP   RIDSSN+NP  +WN G Q+VALNYQT  + MQ+N  KF  NGG G
Sbjct: 624  -FNQRQLSRIYPSAYRIDSSNFNPQTYWNVGCQLVALNYQTEGRMMQLNRAKFMVNGGSG 682

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKP  M +  +NP   + +    K   +++++I  + L K        RG    PFVE
Sbjct: 683  YVLKPSLMSKGAFNPLSDEPLPANPKK-QLVIKIISGQQLPKPPDSMLGDRGEIIDPFVE 741

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F +  PE+AL+RF+V D D  G  +F+
Sbjct: 742  VEIIGLPVDC-CKEQTRVVDDNGFNPVWEETLSFTLHMPEVALVRFLVWDHDPIGR-DFV 799

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E +  +++ VH+++
Sbjct: 800  GQRTIAFSSLMPGYRHV-----YLEGMTEASIFVHITV 832


>UniRef50_Q9BRC7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta 4; n=24; Tetrapoda|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta 4 - Homo sapiens (Human)
          Length = 762

 Score =  237 bits (579), Expect = 2e-60
 Identities = 133/378 (35%), Positives = 213/378 (56%), Gaps = 15/378 (3%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECE 127
           +  I DV+ +R G  S+      EE   L   + FTI ++G    L     +A + +E +
Sbjct: 60  SFSISDVETIRNGHDSELLRSLAEE---LPLEQGFTIVFHGRRSNL---DLMANSVEEAQ 113

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFY-SIENSHEKITLKEVKAFLPKINCKISTS 186
            W++G+  L+    S  +  ++++WL   F    +N   K++ +EV+  L  +N ++   
Sbjct: 114 IWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQE 173

Query: 187 KLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQN 246
               +FQ  DT + G +  ++F   Y K +     VQ++F+ +S   ++G  +TL EF +
Sbjct: 174 YAFSLFQAADTSQSGTLEGEEFVQFY-KALTKRAEVQELFESFS---ADGQKLTLLEFLD 229

Query: 247 FLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDK 306
           FL++EQ +     E+ A + I  Y       +     ++  F+  L SK   I++     
Sbjct: 230 FLQEEQKERDCTSEL-ALELIDRYEPSDSGKLRH-VLSMDGFLSYLCSKDGDIFNPACLP 287

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           + QDMT+PL+HY+I SSHNTYL GDQ   +SS+E Y+R L+ GCRC+E+D WDGP G P 
Sbjct: 288 IYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPV 347

Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426
           +YHGHTLT++I F DV+ T+ ++AF TS+YP+ILS+E +CS  QQ+ MA    ++ G+ L
Sbjct: 348 VYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQL 407

Query: 427 LVHPMD-KNETSLPSPHD 443
           L   +D    T LPSP +
Sbjct: 408 LSTTLDGVLPTQLPSPEE 425



 Score =  195 bits (476), Expect = 5e-48
 Identities = 109/266 (40%), Positives = 158/266 (59%), Gaps = 11/266 (4%)

Query: 938  ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997
            +S L+IY +SV+F       + + + E+SSF ETKA+RL+ +  N F V+++T QLSR+Y
Sbjct: 493  LSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEF-VQHNTWQLSRVY 551

Query: 998  PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055
            P G R DSSNYNP   WN G QMVA+N QT    M +  G F+QNGGCG++LKP F+   
Sbjct: 552  PSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDI 611

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGT-ASPFVEVEIIGADYDSGV 1111
            +  ++P  +K I    K  T++++VI  + L    KT  G+   P V+V+I G   D+  
Sbjct: 612  QSSFHP--EKPI-SPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDT-A 667

Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
            +  T  V +NG NP W     F V  PELA++RFVV D D     +FIGQ T P  C+++
Sbjct: 668  RQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQ 727

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GYR + L +     L  +++ V++ I
Sbjct: 728  GYRHIHLLSKDGISLRPASIFVYICI 753


>UniRef50_Q8K3R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta 4; n=11; Theria|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta 4 - Mus musculus (Mouse)
          Length = 807

 Score =  236 bits (578), Expect = 2e-60
 Identities = 138/414 (33%), Positives = 227/414 (54%), Gaps = 22/414 (5%)

Query: 72  IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECEAWV 130
           I DV+ +R G+ S +  R+  E   LE    FT+ ++G    L     VA + +E + W+
Sbjct: 63  ISDVERIRKGQDS-ELLRYLVEEFPLEQG--FTVVFHGRRPNL---DLVANSVEEAQIWM 116

Query: 131 KGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLR 189
           +G+  L+    S  +  Q+++ L + F   + + + +++ +E +  L  +N ++      
Sbjct: 117 RGLQLLVDLVASMDHQEQMDQMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAF 176

Query: 190 DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249
            +FQ+ D  +  ++G ++F   Y K +     +++IF+ +S   S+   +TL EF +FLR
Sbjct: 177 SLFQEADVTQSDDLGSEEFVQFY-KALTKRTEIEEIFEDFS---SDKQKLTLLEFVDFLR 232

Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ 309
            EQ +   D     +  + D     +        +   F++ L SK  +I++S    + Q
Sbjct: 233 KEQKEK--DHAPDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQ 290

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH 369
           DMT+PLSHY+I+SSHNTYL GDQ   +SS+E Y+R L+ GCRC+E+D WDGPDG P +YH
Sbjct: 291 DMTQPLSHYYINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYH 350

Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVH 429
           GHTLT++I F DVL T+ ++AF +S+YPLILS+E++C+  QQR MA    ++ G+ LL +
Sbjct: 351 GHTLTSRILFKDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRN 410

Query: 430 PMD-KNETSLPSPHD-------XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLD 475
            ++     S+PSP                      E  EE    + ++EG DLD
Sbjct: 411 TLEGLLVDSMPSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLD 464



 Score =  175 bits (425), Expect = 8e-42
 Identities = 99/279 (35%), Positives = 155/279 (55%), Gaps = 11/279 (3%)

Query: 928  MERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVK 987
            +  T  +  ++S L++Y R+V F       + +   ++SSF E+KA+ L+ +  N F V+
Sbjct: 528  LSSTTIMCPDLSALVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEF-VQ 586

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047
            ++  QL R+YP G R DSSN+NP   WN G QMVA+N QT    M +  G F+QNGG G+
Sbjct: 587  HNARQLCRVYPSGLRTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGY 646

Query: 1048 ILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVE 1101
            +LKP+F+   +  +NP    S+    K   ++++VI  + L K  +        P V+VE
Sbjct: 647  VLKPEFLRDTQSSFNPERPISL---YKAQILVVQVISGQQLPKVDKTKETTVVDPLVKVE 703

Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQ 1161
            + G   D+  +  T  V +NG+NP W +   F +  PELA++RFVV+D       NFIGQ
Sbjct: 704  LYGVPEDT-KEQETSHVENNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQ 762

Query: 1162 ATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSIITD 1200
             T P  C+++GYR V L +     L  +++ V+  +  D
Sbjct: 763  YTLPWTCMKQGYRHVSLLSRDGTSLNPASIFVYTCMQED 801


>UniRef50_UPI0000F1EF3B Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 750

 Score =  234 bits (573), Expect = 9e-60
 Identities = 133/374 (35%), Positives = 210/374 (56%), Gaps = 17/374 (4%)

Query: 72  IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYY-GTEFKLRCASFVAQTDKECEAWV 130
           I DV+ VR G  S+      +E       +CFT+ + G +  L     VA++ +E +AW+
Sbjct: 63  ISDVEAVREGHQSEALLGVADE---FPPDRCFTLVFRGRKGNL---DLVAESAEEAQAWI 116

Query: 131 KGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLR 189
           +GV  L+    +     ++++W+   F   + N   +I  KE K  L  +N  ++     
Sbjct: 117 QGVRGLMENMENMDESTKLDQWISDWFSKADRNKDGRINFKEAKKLLKMMNIDMNEEHAC 176

Query: 190 DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249
            +F+  D  + G +   +F   Y K++ +   V D+F  YS   S+G  ++  + + FLR
Sbjct: 177 CLFKMADKSRSGTLEDQEFVEFY-KMLTERREVLDLFQDYS---SDGQILSQCDLEEFLR 232

Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPY-FTLSEFVEMLYSKQNSIYDSQYDKVT 308
           +EQ +     E  A Q I  Y  +P       +  ++  F+  L S + SI++ +   + 
Sbjct: 233 EEQLEGESSYE-HALQLIDRY--EPSETARMNHSMSVDGFLMYLTSPEGSIFNPERQGIF 289

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
           QDM++ L+HY+ISSSHNTYL  DQ    SS+EAY++ L+ GCRC+E+DCW+G +G P +Y
Sbjct: 290 QDMSQSLAHYYISSSHNTYLMEDQLKGPSSVEAYIQALKRGCRCVEVDCWNGANGEPVVY 349

Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
           HGHT T+KI   DV+ TI  +AF  SEYPLI+SIE++CS+ QQ+ MA  F+++ GD+LL 
Sbjct: 350 HGHTFTSKILLKDVITTIASYAFKASEYPLIISIENHCSVEQQKVMAQQFREILGDMLLT 409

Query: 429 HPMDKNETS-LPSP 441
              D   +S LPSP
Sbjct: 410 STADTEVSSELPSP 423



 Score =  202 bits (494), Expect = 3e-50
 Identities = 116/270 (42%), Positives = 159/270 (58%), Gaps = 11/270 (4%)

Query: 934  IAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            + KE+SD I++C+SV F+  E  RI    Y EMSSF E+KA R  S++  + FV ++T Q
Sbjct: 475  LCKELSD-IMFCKSVHFHSFEHSRISAKPY-EMSSFSESKA-RKYSKEAGSDFVLHNTRQ 531

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L R+YP G R DSSNY PV  W+ G Q+VALN+QT    M +N G F QNG  G++LKP+
Sbjct: 532  LIRVYPSGMRTDSSNYCPVDMWSMGCQIVALNFQTAGMEMDLNDGLFSQNGCSGYVLKPE 591

Query: 1053 FM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGADY 1107
             +   E  ++P +K        P+   ++VI  + L K  +   S   PFV VEI G   
Sbjct: 592  ILRNRERRFDP-EKPEEHEDYNPLVFSVKVISGQQLPKLKQNEWSIVDPFVRVEIYGVPL 650

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   K  TK + +NG NP WN+  +F V  PELAL+RFVV+D D     +FIGQ T PL 
Sbjct: 651  DQ-AKQETKYIDNNGFNPYWNESVQFTVHTPELALVRFVVEDHDKASRNDFIGQYTLPLS 709

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            C++ GYR V L +     +  S++ VH+ I
Sbjct: 710  CIQPGYRHVHLLSKDGTSIRPSSIFVHIKI 739


>UniRef50_A5D6R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-3; n=14; Euteleostomi|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-3 - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 784

 Score =  232 bits (568), Expect = 4e-59
 Identities = 140/430 (32%), Positives = 223/430 (51%), Gaps = 19/430 (4%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + +GS ++K   ++  + R L +  +   V        ++   +    + +V+ 
Sbjct: 34  DEDVLLMLQGSKMMKVRSQRWRKDRRLKLLEDCVTVWCESSKTSRKSNRQQTFSVTEVEC 93

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  S+   R    T  +    CFT+ +    K         T +E E WV+G+  L 
Sbjct: 94  VREGCQSECLRRM---TDLVPEKNCFTVVFRGGRK--SLDLCCHTQEEAERWVRGIRTLK 148

Query: 138 AEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
               + S   +++ W+R      + + + K++  EVK  L  IN  ++    R +F+  D
Sbjct: 149 DRVSNMSQKEKLDHWIRGYLRRADQNQDGKMSYDEVKHLLQLINIDLNEQYARTLFKKCD 208

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
               G +   +     ++++     +  +F  YS    NG  +T  E ++FL D+  D  
Sbjct: 209 RSCDGRLDHVEIEEFCREMM-RRPELDAVFRHYS---GNGCVLTTLELRDFLGDQGEDA- 263

Query: 257 GDDEVQASQFIRDY-LRD-PQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRP 314
               V A   I+ + L D  Q++++    T + F   + SK+N +++  +  V QDM++P
Sbjct: 264 --SLVHAKSLIQTFELNDWAQKNLF---MTQNGFTMYMLSKENDVFNPDHTHVYQDMSKP 318

Query: 315 LSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLT 374
           L+HY+ISSSHNTYLT DQ +S SS E Y+R L  GCRC+ELDCWDG  G P IYHGHTLT
Sbjct: 319 LAHYYISSSHNTYLTKDQVTSASSTEPYIRALNQGCRCVELDCWDGDKGEPIIYHGHTLT 378

Query: 375 TKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPM-DK 433
           +K+ F +V+ TI ++AF  S YPLILS+E++CS+ QQ  MA   Q + G  LL  P+ D 
Sbjct: 379 SKVLFKEVIETIAQYAFKASPYPLILSLENHCSVEQQAIMAQQLQSILGKKLLAKPLSDL 438

Query: 434 NETSLPSPHD 443
               LPSP +
Sbjct: 439 PLKQLPSPEE 448



 Score =  194 bits (474), Expect = 9e-48
 Identities = 106/276 (38%), Positives = 161/276 (58%), Gaps = 12/276 (4%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            +++ E+SDL++YC+SV F+  E    +    + ++SF E +A +L+ +     FV+ ++ 
Sbjct: 501  KLSPELSDLVVYCQSVPFSGFETANQRP--PSVITSFSENEALKLI-KDSGKLFVRNNSR 557

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
            QLSRIYP  QR+ SSN++P   WN G QMVALN+QTP + M +N G+F  NG CG++LKP
Sbjct: 558  QLSRIYPSAQRLQSSNFDPQDMWNAGCQMVALNFQTPGEQMDLNQGRFLPNGRCGYVLKP 617

Query: 1052 QFMFE--EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG----RGTASPFVEVEIIGA 1105
            +F+ +    ++P +     G + P  + +RVI A+ L K           P V VEI G 
Sbjct: 618  EFLCDPKSDFDPENTGGGPGHI-PTQLTIRVISAQQLPKINTDKPNSIVDPQVWVEIHGV 676

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   +  T+ + +NG NP W+    F++  PELAL+RF+V+D D   + +FIGQ T P
Sbjct: 677  SIDK-ARAKTQRIDNNGFNPRWDCTVSFQLQLPELALVRFMVEDHDHKSKNDFIGQFTLP 735

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIITDG 1201
               LR GYR V L  A    L  +TL +H+ ++  G
Sbjct: 736  FTSLRTGYRHVHLLKADGSTLSPATLFIHVKVVRRG 771


>UniRef50_Q8N3E9 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-3; n=22; Euteleostomi|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-3 - Homo sapiens (Human)
          Length = 789

 Score =  231 bits (565), Expect = 9e-59
 Identities = 143/460 (31%), Positives = 230/460 (50%), Gaps = 18/460 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + RGS + K   R   + R   ++ +   V W +   P R   +    ++ ++ 
Sbjct: 59  DEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSV-WFQRRIP-RAPSQHIFFVQHIEA 116

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  S+   R+         ++C TI +  + + +     A T +E + WV+G+  L 
Sbjct: 117 VREGHQSEGLRRFGGA---FAPARCLTIAF--KGRRKNLDLAAPTAEEAQRWVRGLTKLR 171

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
           A   + S   +++ W+    +  + N   K++ KE+K+ L  +N  ++      +F++ D
Sbjct: 172 ARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECD 231

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
                 +   +     ++L+     +++IF +YS        ++  E   FL D+  +  
Sbjct: 232 HSNNDRLEGAEIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE-- 285

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
           G    +A Q I+ Y  +     +E   TL  F+  L S + +  D+ +  V QDM +PL+
Sbjct: 286 GATLARAQQLIQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLA 344

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY+ISSSHNTYLT  Q    SS EAYVR    GCRC+ELDCW+GP G P IYHGHTLT+K
Sbjct: 345 HYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSK 404

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NE 435
           I F DV++ +++HAF  S YP+ILS+E++C L QQ  MA     + GD+L+   +D  N 
Sbjct: 405 ILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNP 464

Query: 436 TSLPSPHDXXXXXXXXXXXXPEGAEESSFAV--RQEEGKD 473
             LPSP              P    E   A+  R+EE +D
Sbjct: 465 EELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEED 504



 Score =  168 bits (408), Expect = 9e-40
 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I+ E+S L +YC +                ++SS  E KA++L+ +  N+F V+++  Q
Sbjct: 523  QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 581

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L+R+YP G R++S+NY+P   WN G Q+VALN+QTP   M +N G+F  NG CG++LKP 
Sbjct: 582  LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 641

Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107
             + +    P      E    P  T+ ++V+ A+ L K           P V +EI G   
Sbjct: 642  CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 697

Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
            D   +  T  V +NG NP W    +F++  PELAL+RFVV+D D     +F+GQ T PL 
Sbjct: 698  DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 756

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L++GYR + L +     L  +TL + + I
Sbjct: 757  SLKQGYRHIHLLSKDGASLSPATLFIQIRI 786


>UniRef50_P51178 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-1; n=43; Euteleostomi|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase delta-1 - Homo sapiens (Human)
          Length = 756

 Score =  231 bits (564), Expect = 1e-58
 Identities = 132/425 (31%), Positives = 216/425 (50%), Gaps = 13/425 (3%)

Query: 18  DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77
           D+ +  + +GS +LK        R      +E  + +W       R        I D++E
Sbjct: 16  DEDLQALLKGSQLLKV-KSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQE 74

Query: 78  VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137
           VR G  ++  E++  +   +   +CF+I +  +        +A +  + + WV G+  +I
Sbjct: 75  VRMGHRTEGLEKFARD---VPEDRCFSIVFKDQ--RNTLDLIAPSPADAQHWVLGLHKII 129

Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196
             + S     +++ W+       + N   K++ KE++ FL ++N ++  S  R +F++ D
Sbjct: 130 HHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECD 189

Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256
             +   +  ++    Y+ L        +I   ++     G T+++ +   FL+ +Q +  
Sbjct: 190 HSQTDSLEDEEIEAFYKML----TQRVEIDRTFAEAAGPGETLSVDQLVTFLQHQQREEA 245

Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316
               +  S  I  Y    +    +   T   F+  L S   S +   + +V QDM +PLS
Sbjct: 246 AGPALALS-LIERY-EPSETTKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLS 303

Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376
           HY +SSSHNTYL  DQ +  SS EAY+R L  GCRC+ELDCWDGP+  P IYHG+T T+K
Sbjct: 304 HYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSK 363

Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET 436
           I F DVLR I+++AF  S YP+ILS+E++C+L QQR MA     + G +LL  P+D    
Sbjct: 364 ILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTN 423

Query: 437 SLPSP 441
           SLPSP
Sbjct: 424 SLPSP 428



 Score =  196 bits (477), Expect = 4e-48
 Identities = 112/272 (41%), Positives = 161/272 (59%), Gaps = 11/272 (4%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            R+A+E+SD++IYC+SV F         G  + EM+SF E +A RL+ +  N F V+++  
Sbjct: 487  RLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGF-VRHNVG 545

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             LSRIYP G R DSSNY+PV  WN G Q+VALN+QTP   M V   +F+ NG CG++LKP
Sbjct: 546  HLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQDRFQDNGACGYVLKP 605

Query: 1052 QFMFEEG--YNPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGA 1105
             F+ +    +NP  +   +G       + +RVI  + L K  +   S   P V VEI G 
Sbjct: 606  AFLRDPNGTFNP--RALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGV 663

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   +  T  +++NG NP W+    FEV  P+LALIRF+V+D D   + +FIGQ+T P
Sbjct: 664  SRDVASR-QTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIP 722

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  L++GYR V L +   ++   +TL V +S+
Sbjct: 723  LNSLKQGYRHVHLMSKNGDQHPSATLFVKISL 754


>UniRef50_Q4RX70 Cluster: Chromosome 11 SCAF14979, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 11 SCAF14979, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1158

 Score =  225 bits (550), Expect = 6e-57
 Identities = 113/293 (38%), Positives = 181/293 (61%), Gaps = 9/293 (3%)

Query: 152 WLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFA 209
           WL++ F   + + +  +++ EV   L K+N  +   K+R +FQD DT E +G +GF++F 
Sbjct: 159 WLQQTFSEADKNRDGTLSIGEVHQLLHKLNVNLPKQKVRQMFQDADTDENQGSLGFEEFC 218

Query: 210 VLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269
             Y K+I    ++  I   YS   +    + L +  +FL +EQ    G  +   +  +  
Sbjct: 219 SFY-KMISTRRDLYLIMISYS---NQKEVMDLHDLAHFLENEQKMR-GLTKEHLADIVAK 273

Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLT 329
           +   P+ ++      +  F   + S    I++ ++++V QDMT+PL+HY+I++SHNTYL+
Sbjct: 274 FEPCPE-NLQHMVLGIDGFTNFMRSPAGDIFNPEHNEVNQDMTQPLNHYFIATSHNTYLS 332

Query: 330 GDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389
           GDQ  S+S +E Y   L++GCRC+E+DCWDGPDG P I+HG+TLT+KI F DV+ TI +H
Sbjct: 333 GDQLLSQSRVEMYAYVLQAGCRCVEVDCWDGPDGEPIIHHGYTLTSKILFKDVIETINKH 392

Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSP 441
           AF  S+YP+ILSIE++CS+PQQ++MA   ++V  D L +  +  N+   LPSP
Sbjct: 393 AFTKSQYPVILSIENHCSVPQQKKMAEYLKEVLQDKLDLSVVISNDCKRLPSP 445



 Score =  175 bits (427), Expect = 5e-42
 Identities = 98/248 (39%), Positives = 146/248 (58%), Gaps = 14/248 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYN-EMSSFPETKAERLMSQQENTFF 985
            K  +T R+++ +SDL+ Y +SV   +  +  + F  + ++SS  ET   +++ Q + +  
Sbjct: 599  KKRKTMRLSRALSDLVKYTKSV--RVHDIETQAFTNSWQVSSLNETVMNQII-QLKPSEL 655

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            V+ +  QL R+YP   R+DSSN+NP P+WN G  MVALNYQT  + +++N  KF  NG C
Sbjct: 656  VRLNQRQLLRVYPSNYRVDSSNFNPQPYWNTGCHMVALNYQTEGRMLELNRAKFSANGNC 715

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G+ILKP+ M +  +NP  +  + G+ K   ++L+VI  + L K        RG    PFV
Sbjct: 716  GYILKPKCMRKGAFNPTLEDPLPGRRK-TQLVLKVISGQQLPKPKDSMFGDRGEIIDPFV 774

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   K  T+ V DNG NP+W +   F +  P++AL+RF V D D  G+ +F
Sbjct: 775  EVEIIGLPMDCS-KQQTRVVEDNGFNPMWEETLVFNIQMPQVALVRFQVWDHDPIGQ-DF 832

Query: 1159 IGQATFPL 1166
            IGQ T  L
Sbjct: 833  IGQRTIAL 840


>UniRef50_Q4SNU6 Cluster: Chromosome 15 SCAF14542, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
           SCAF14542, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 828

 Score =  223 bits (546), Expect = 2e-56
 Identities = 144/450 (32%), Positives = 224/450 (49%), Gaps = 34/450 (7%)

Query: 16  EADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDV 75
           E D  + ++ +GS +LK   R   + R   ++ +  + +W       +     +LD  D+
Sbjct: 3   EGDLDLDFLLKGSDLLKVRSRNWKKTRYFKLQEDC-KTMWLESKKLIKSNQTFSLD--DI 59

Query: 76  KEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLY 135
             VR G+ ++   +  EE  ++E  +CF+I +  + + +    +A +D+E   WV  +  
Sbjct: 60  SAVRVGRQTEGLRKSTEE--QVED-RCFSIVF--KGRRKNLDLIAGSDEEARRWVSSLQK 114

Query: 136 LIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQD 194
           L++   + S   + E W+       + N  +K+T  E+K FL  IN ++       +FQ 
Sbjct: 115 LVSNLNNLSRKQKTEHWILSCLRKADKNKDDKLTQSEMKNFLRLINIEVDDIYAEMLFQK 174

Query: 195 VDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHD 254
            D  K G +  ++    Y  L   E    +I   Y  Y      ++      FL  EQ +
Sbjct: 175 CDKSKSGYLAGEEIEHFYDLLTHRE----EINVIYGAYARTTGFMSPENLVEFLMKEQRE 230

Query: 255 ------------NLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSE--------FVEMLYS 294
                       N   DE   S F    L  P  D      T+ E        F+  L+ 
Sbjct: 231 KATLADANSIIKNFEPDENGESSFFYPLLSGPDPDSRLRVPTVKEKQLLSKDGFLLYLHH 290

Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354
            +  I ++++ +V QDM+RPLSHY+ISSSHNTYL  DQ    SS EAYVR L+ GCRC+E
Sbjct: 291 PETMILNAEHKEVYQDMSRPLSHYFISSSHNTYLMEDQLKGPSSTEAYVRALQKGCRCVE 350

Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414
           LDCWDG D  P IYHG+TLT++I F D ++ IK++AF  S+YP+ILS+E++CS+ QQ+ M
Sbjct: 351 LDCWDGSDNEPVIYHGYTLTSQILFKDAVKAIKDYAFQASDYPVILSLENHCSVKQQQVM 410

Query: 415 ASAFQDVFGDLLLVHPM-DKNETSLPSPHD 443
           A     + G  L+  P+ D   T  PSP +
Sbjct: 411 AHHLSSILGSALVTSPLGDTMPTDFPSPEE 440



 Score =  120 bits (289), Expect = 2e-25
 Identities = 64/136 (47%), Positives = 84/136 (61%), Gaps = 15/136 (11%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            ++AKE+SD++IYC+SV F+      K   + EMSSF E KA +L  +  N + ++++  +
Sbjct: 492  KLAKELSDMVIYCKSVHFSGFEDARKNLSFYEMSSFKEGKAVKLAEESANEY-IRHNAEK 550

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQM--------------VALNYQTPDKPMQVNMGK 1038
            LSRIYP G R DSSNYNPVP WN G QM              VALN+QT    M VN G+
Sbjct: 551  LSRIYPAGVRTDSSNYNPVPLWNAGCQMGTGCSPKPQGLRSKVALNFQTACSDMDVNQGR 610

Query: 1039 FKQNGGCGFILKPQFM 1054
            F+ NG  G+ILKP FM
Sbjct: 611  FQVNGKSGYILKPAFM 626


>UniRef50_UPI000069F421 Cluster: phospholipase C delta 3; n=1;
           Xenopus tropicalis|Rep: phospholipase C delta 3 -
           Xenopus tropicalis
          Length = 790

 Score =  220 bits (537), Expect = 2e-55
 Identities = 125/370 (33%), Positives = 205/370 (55%), Gaps = 16/370 (4%)

Query: 75  VKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVL 134
           ++ VR G  S+  +++    +R   + CFTI +  + + +     A ++KE   WV+G+ 
Sbjct: 66  IESVREGHQSEGLQKYG---RRFPETCCFTIAF--KGRRKNLDLAASSEKEALNWVQGLQ 120

Query: 135 YLIAEAVSASYPLQIERWLRKEFY--SIENSHEKITLKEVKAFLPKINCKISTSKLRDVF 192
            L+  A + S   ++ ++   ++   +  +  EK+T +EVK  L  IN  ++     ++F
Sbjct: 121 KLMKRAEAMSQREKLVQYPVNDYLRQADRDGDEKMTFQEVKDMLKMINIDLNDIYAYNLF 180

Query: 193 QDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252
           +  D      +   +      KL+     V++IF  YS        ++  E Q FL+ + 
Sbjct: 181 KACDRSNTNTLEDHEIEEFCTKLMH-RPEVEEIFHHYS---GEDRVLSAEELQEFLQAQG 236

Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312
            D   +   +A + I+ Y  +     ++    +  F+  L S    I++ ++    QDMT
Sbjct: 237 EDATLE---RAKELIQKYELNETAKQHD-LMMMEGFMMYLLSDDGDIFNQKHRMAYQDMT 292

Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT 372
           +PL HY+ISSSHNTYLT  Q   ESS E+Y+R    GCRC+ELDCW+GP G P IYHGHT
Sbjct: 293 QPLCHYFISSSHNTYLTNHQLVGESSTESYIRVFMEGCRCVELDCWEGPSGEPVIYHGHT 352

Query: 373 LTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432
           LT+KI F DV+ TI+++AF  S YP+ILS+E++C L QQ +MA+  +++ GD+L+  P+ 
Sbjct: 353 LTSKILFKDVVTTIRDYAFKNSPYPVILSLENHCGLEQQVKMANHLREILGDMLVTKPVP 412

Query: 433 KNETS-LPSP 441
             +T+ LPSP
Sbjct: 413 GADTARLPSP 422



 Score =  200 bits (489), Expect = 1e-49
 Identities = 117/269 (43%), Positives = 159/269 (59%), Gaps = 19/269 (7%)

Query: 935  AKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            AKE+SDL++YC++V +  +     G V  EMSSF E K  RL+ +      V+Y+  QLS
Sbjct: 526  AKELSDLVVYCQTVEYRGQ----PGNVC-EMSSFSEDKVRRLI-KDSGINLVRYNARQLS 579

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYP G R +SSNY P   WN G Q+VALN+QTP   M +N G+F+ NG CG++LKP+F+
Sbjct: 580  RIYPDGLRANSSNYCPQEMWNAGCQLVALNFQTPGYTMDLNRGRFQDNGLCGYVLKPEFL 639

Query: 1055 FEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVEIIGADYD 1108
             +E   +NP D  S E    P  + ++VI A+ L K  +        PFV VEI G    
Sbjct: 640  RKEDSYFNP-DSPSKE----PKLLFVKVISAQQLPKLNKEKPNSIVDPFVRVEIHGVGKK 694

Query: 1109 SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168
               +  TK + +NG NP WN+I + EV  PELAL+RFVV+D D     +F+GQ T P L 
Sbjct: 695  K--EKETKYILNNGFNPYWNEILQLEVQVPELALVRFVVEDYDKTSSNDFVGQYTLPFLS 752

Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L++GYR V L +     L  +TL V + I
Sbjct: 753  LKQGYRHVHLLSKDGASLSPATLFVQIRI 781


>UniRef50_Q5QIB9 Cluster: Phospholipase C delta isoform; n=6;
           Strongylocentrotus purpuratus|Rep: Phospholipase C delta
           isoform - Strongylocentrotus purpuratus (Purple sea
           urchin)
          Length = 753

 Score =  219 bits (536), Expect = 3e-55
 Identities = 136/474 (28%), Positives = 232/474 (48%), Gaps = 26/474 (5%)

Query: 16  EADQLISYIERGSTVLKFFPRKRPER-RALCVRRETHQVLWSRINAPQRQGYEGALDIRD 74
           + +Q+   ++RG+   K  P    +  R   +  +   ++++     ++   +  + + +
Sbjct: 7   QVEQIHQKLKRGTKFTKISPNSTKKHGRTFSLTDDGTALMYT---PSKKSSSKATVSLSE 63

Query: 75  VKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVL 134
           + E+R+G  +  F R  +  K+    + F++  G E      + VA +  +   WV G+ 
Sbjct: 64  IHEIRSGHETDTF-RISKNKKKYPKERSFSLIVGNEN--HTVNLVAPSQDDARTWVMGLR 120

Query: 135 YLIAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQ 193
           +L  ++       +   W+   F   +   +  +   E    L K+N KI     + +FQ
Sbjct: 121 WLKKKSQHIDIHSKQAAWIMDAFRQADVDRDGTVDFDESYKLLKKLNIKIEKVHAKRLFQ 180

Query: 194 DVDTE----KRGEIGFD----DFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245
             +T     K+G++  D    D  V + ++I    ++Q++F KYS    +    T  EF 
Sbjct: 181 FANTHSTTTKKGKVRSDALSEDEFVEFYRIITRRPDLQEVFKKYS---GDDDYWTPEEFA 237

Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFVEMLYSKQNSIYDSQY 304
            F+ +EQ       E  A+  I +Y  +P ++  +    T+  F   +      I++  +
Sbjct: 238 EFMHEEQKRLEVTPEWCATN-IEEY--EPNQEFRDQKILTMDGFFLFMMGPSGLIFNPFH 294

Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT 364
           + V QDM +PL+HY+I+SSHNTYL  DQ    SS EAY+  L+ GCRC+ELDCWDGPD  
Sbjct: 295 EDVYQDMKQPLAHYFINSSHNTYLLDDQLRGPSSTEAYISALQRGCRCVELDCWDGPDND 354

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P +YHGHTLT+KI+F D++  + ++AF  SEYPLILS E++CS+ QQ+ MA     +  D
Sbjct: 355 PIVYHGHTLTSKIKFRDIIEVVDKYAFAASEYPLILSFENHCSVEQQKVMAQICVSILKD 414

Query: 425 LLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA---EESSFAVRQEEGKDLD 475
            L  +    NE + PSP +            P  A   E+      ++E  D+D
Sbjct: 415 KLYTNNNLHNEAAFPSPEELKGKILIKGKSLPPSAATTEDDGEVSDEDEAADID 468



 Score =  179 bits (436), Expect = 4e-43
 Identities = 107/269 (39%), Positives = 152/269 (56%), Gaps = 12/269 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            ++AKE+SDL+    SV +       + +  ++MSSF E KA  L   +   + V+++   
Sbjct: 490  KLAKELSDLVTLA-SVHYGSFPASKEKYKCHQMSSFGEAKAFGLAEDKPGDY-VEHNKIF 547

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYP G R +SSNY+PVP W+ G+Q+VALN+QTP + M +N GKF QNG  GFILKP 
Sbjct: 548  LSRIYPGGLRTNSSNYSPVPMWDVGAQIVALNFQTPCEEMDLNQGKFLQNGKSGFILKPV 607

Query: 1053 FMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEVEIIGADYD 1108
            F  +    +NP       G      V L VI  + L K    +    P+V+V ++G    
Sbjct: 608  FCRKPNMQFNPLK----PGDQYTQHVTLTVISGQQLPKPSGSKEVIDPYVKVYVLGG--G 661

Query: 1109 SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168
            S  +  T+ V +NG +P WN    FEV  PELALIR VVQD D+     FIGQ TFP+  
Sbjct: 662  SKQEFKTEVVENNGFSPTWNQEFSFEVKVPELALIRLVVQDYDMASSNEFIGQYTFPVAS 721

Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            ++ GY  VP+     ++L  ++L +H  +
Sbjct: 722  MQLGYHHVPILGEKGDDLLPASLFIHTMV 750


>UniRef50_UPI00006609DC Cluster: Homolog of Brachydanio rerio
            "Phospholipase C gamma 1.; n=3; Euteleostomi|Rep: Homolog
            of Brachydanio rerio "Phospholipase C gamma 1. - Takifugu
            rubripes
          Length = 304

 Score =  217 bits (531), Expect = 1e-54
 Identities = 97/184 (52%), Positives = 135/184 (73%), Gaps = 2/184 (1%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +MER  +IA E+S+L++YCR V FN +++      Y +MSSFPETKAE+  ++     F+
Sbjct: 123  QMERRKKIAVELSELVVYCRPVPFNEDKIGTDRACYKDMSSFPETKAEKFTTRSRGKRFL 182

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +Y+  QLSR+YP+GQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N   F   GG G
Sbjct: 183  QYNRRQLSRVYPRGQRLDSSNYDPLPMWLCGSQLVALNFQTPDKPMQLNQAFFLLGGGSG 242

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGAD 1106
            ++ +P  M ++ ++P DK ++   V+P+T+ L+V+GARHL K GR    PFVEVEI GAD
Sbjct: 243  YVPQPDVMRDDIFDPFDKDTV--TVEPITIQLQVLGARHLPKNGRSIVCPFVEVEICGAD 300

Query: 1107 YDSG 1110
            YDSG
Sbjct: 301  YDSG 304



 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 40/74 (54%), Positives = 54/74 (72%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           T++ TVKALYDYRA+++DEL F K A++ NVDK + GWWRGDYGGK+  WFPANYV E+ 
Sbjct: 48  TARCTVKALYDYRAQREDELCFPKQALVLNVDKQEGGWWRGDYGGKKQLWFPANYVEELP 107

Query: 836 VPHTPDVTSGLENE 849
                ++   ++ E
Sbjct: 108 SSPVRELDEAMQEE 121


>UniRef50_Q86XJ2 Cluster: PLCH2 protein; n=8; Euteleostomi|Rep:
           PLCH2 protein - Homo sapiens (Human)
          Length = 1238

 Score =  216 bits (527), Expect = 3e-54
 Identities = 107/294 (36%), Positives = 177/294 (60%), Gaps = 9/294 (3%)

Query: 151 RWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDF 208
           +WL++ F   + N    +++ EV   L K+N  +   +++ +F++ DT+  +G +GF++F
Sbjct: 30  KWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEF 89

Query: 209 AVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIR 268
              Y+ +    +  +D++     Y ++   +     Q FL+ EQ   +    +++ Q I 
Sbjct: 90  CAFYKMM----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDII 143

Query: 269 DYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYL 328
           +       +  +    +  F     S    I++ ++  V QDMT+PLSHY+I+SSHNTYL
Sbjct: 144 EQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYL 203

Query: 329 TGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKE 388
            GDQ  S+S ++ Y   L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +
Sbjct: 204 VGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINK 263

Query: 389 HAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSLPSP 441
           +AFI +EYP+ILSIE++CS+ QQ++MA    D+ GD L L     ++ T+LPSP
Sbjct: 264 YAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSP 317



 Score = 86.6 bits (205), Expect = 4e-15
 Identities = 43/104 (41%), Positives = 68/104 (65%), Gaps = 5/104 (4%)

Query: 927  KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            + ++T ++++ +SDL+ Y +SV T +IE      +   ++SSF ETKA +++ QQ+   +
Sbjct: 473  RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 528

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPD 1029
            ++++  QLSRIYP   R+DSSNYNP PFWN G QM   N  + D
Sbjct: 529  LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMGVFNPNSED 572



 Score = 83.0 bits (196), Expect = 4e-14
 Identities = 55/146 (37%), Positives = 78/146 (53%), Gaps = 15/146 (10%)

Query: 1059 YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRGTA-SPFVEVEIIGADYDSGV 1111
            +NP  +  + G++K   V LR+I  + L K        RG    PFVEVEIIG   D   
Sbjct: 566  FNPNSEDPLPGQLKKQLV-LRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCS- 623

Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
            +  T+ V DNG NP W +   F V  PE+AL+RF+V D D  G  +FIGQ T     +  
Sbjct: 624  REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DFIGQRTLAFSSMMP 682

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GYR V     + E +E +++ VH+++
Sbjct: 683  GYRHV-----YLEGMEEASIFVHVAV 703


>UniRef50_UPI000065E113 Cluster: Homolog of Homo sapiens
           "PhosPholiPase C-like 3; n=1; Takifugu rubripes|Rep:
           Homolog of Homo sapiens "PhosPholiPase C-like 3 -
           Takifugu rubripes
          Length = 1130

 Score =  215 bits (524), Expect = 8e-54
 Identities = 111/293 (37%), Positives = 177/293 (60%), Gaps = 9/293 (3%)

Query: 152 WLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFA 209
           WL++ F   + N    +++ EV   L K+N  +   K+R +FQD DT E +G +GF++F 
Sbjct: 162 WLQQTFSEADKNGDGTLSIGEVHQLLHKLNVNLPKQKVRQMFQDADTDENQGSLGFEEFC 221

Query: 210 VLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269
             Y K+I    ++  I   YS   +    + L +   FL +EQ    G  +      +  
Sbjct: 222 SFY-KMISTRRDLYLIMISYS---NQKEVMDLHDLARFLENEQKMR-GLTKEHLVDIVAK 276

Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLT 329
           +   P+ ++      +  F   + S    I++ ++++V QDMT+ L++Y+I++SHNTYL+
Sbjct: 277 FEPCPE-NLQHMVLGIDGFTNFMRSPAGDIFNPEHNQVNQDMTQALNNYFIATSHNTYLS 335

Query: 330 GDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389
           GDQ  S+S +E Y   L++GCRC+E+DCWDGPDG P I+HG+TLT+KI F DV+ TI ++
Sbjct: 336 GDQLLSQSRVEMYAYVLQAGCRCVEVDCWDGPDGEPIIHHGYTLTSKILFKDVIETIDKY 395

Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE-TSLPSP 441
           AF  S+YP+ILSIE++CS+PQQ++MA   ++V  D L +  +  N+   LPSP
Sbjct: 396 AFTKSQYPVILSIENHCSVPQQKKMAEYLKEVLQDKLDLSVVISNDCKKLPSP 448



 Score =  182 bits (444), Expect = 4e-44
 Identities = 99/248 (39%), Positives = 147/248 (59%), Gaps = 14/248 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYN-EMSSFPETKAERLMSQQENTFF 985
            K  +T R+++ +SDL+IY +SV   +  +  + F  + ++SS  ET   +++ Q +    
Sbjct: 573  KKRKTMRLSRALSDLVIYTKSV--RVHDIETQAFTNSWQVSSLNETVMNQIL-QLKPDHL 629

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            V+++  QL R+YP   R+DSSN+NP P+WN G  MVALNYQT  + +++N  KF  NG C
Sbjct: 630  VRFNQRQLLRVYPSNYRVDSSNFNPQPYWNTGCHMVALNYQTEGRMLELNTAKFSANGNC 689

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098
            G+ILKP++M +  +NP  +  + G+ K   ++L++I  + L K        RG    PFV
Sbjct: 690  GYILKPKYMRKGAFNPTLEDPLPGRRK-TQLVLKIISGQQLPKPKDSMLGDRGEIIDPFV 748

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
            EVEIIG   D   K  T+ V DNG NP+W +   F +  PE+AL+RF V D D  G  +F
Sbjct: 749  EVEIIGLPLDCS-KQQTRVVDDNGFNPMWEETLVFNIQMPEVALVRFQVWDHDPIGR-DF 806

Query: 1159 IGQATFPL 1166
            IGQ T  L
Sbjct: 807  IGQRTIAL 814



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 40/158 (25%), Positives = 74/158 (46%), Gaps = 11/158 (6%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P ++  +  + I  ++EV  GK S+ F R+ +   R + + CF+IY+G   +++    V 
Sbjct: 41  PSKKQDKAKITIDSIQEVCEGKKSEMFRRYADN--RFDPNCCFSIYHGE--RVKSLDLVT 96

Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKA---FLP 177
              +E   WV G+ YL+A  +S    L   R   ++ Y + +     TLK + +    + 
Sbjct: 97  TNAEEARTWVTGLKYLMA-GISDEDSL-ARRQRTRDQYPLSSLCCTNTLKNILSRSWSVF 154

Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKL 215
           ++NC  S + L+  F + D    G +   +   L  KL
Sbjct: 155 RLNC--SVTWLQQTFSEADKNGDGTLSIGEVHQLLHKL 190


>UniRef50_O97037 Cluster: PLC-deltaH; n=1; Hydra magnipapillata|Rep:
           PLC-deltaH - Hydra magnipapillata (Hydra)
          Length = 738

 Score =  212 bits (518), Expect = 4e-53
 Identities = 131/386 (33%), Positives = 197/386 (51%), Gaps = 17/386 (4%)

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
           P  +G    + I D+ ++   +S   FE      K+L      T Y   E K     F  
Sbjct: 57  PSVKGSNFKILIADITDINVAES---FETKICFKKKLLHQFIVT-YKDDENKTHKLGFFV 112

Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKI 179
           +   E   W  G+ YL  E      P+ ++ WLR+ F + + N +  + LKE+   L  +
Sbjct: 113 EDQNEVRFWSSGLQYLSDELKKPEDPI-VDDWLREAFDAADVNKNSLLGLKEISQLLNSL 171

Query: 180 NCKISTSKLRDVFQDVDTEKR----GEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSN 235
           N     S ++  FQ+   E++    G++  + FA  ++   FD+N V  I  +Y      
Sbjct: 172 NISKENSDVKLKFQECCNEEKNNENGKLTRNGFAEFFKFFSFDKNEVSSIIKEYGRTIFG 231

Query: 236 GTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSK 295
            T +     Q + R+ Q  NL  +E +  + I  +  D  R     Y +    + ML S+
Sbjct: 232 KTCLNAESLQKYFREVQQQNLSLEECK--KIISKH--DENRG---SYLSAEGVIRMLISE 284

Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355
           +N I D  +  + QDMTRPL+ Y+I+SSHNTYL  DQ    SS +AY + L+ GC+ +EL
Sbjct: 285 ENDILDPIHKNIHQDMTRPLTDYFINSSHNTYLLNDQVLGMSSTKAYEKALKKGCKTLEL 344

Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415
           DC+DG +  P +YHG TLT+KI F DV+ TI   AF+ SEYP+ILS E++CS  QQ  MA
Sbjct: 345 DCYDGENNEPIVYHGFTLTSKILFKDVIDTIAMGAFVQSEYPVILSFENHCSPEQQIVMA 404

Query: 416 SAFQDVFGDLLLVHPMDKNETSLPSP 441
              ++  G +L    +D N+T LPSP
Sbjct: 405 QHLKEKLGKMLFDGDVDLNQTKLPSP 430



 Score =  173 bits (420), Expect = 3e-41
 Identities = 101/273 (36%), Positives = 148/273 (54%), Gaps = 9/273 (3%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            K ++   +AKE S++I Y  S+TF      +    Y +  S  E K  +L  + E    +
Sbjct: 465  KTKQKINVAKEFSNIINYVESITFKSLDEGLATQKYFQNVSLGEKKLLQL-GRDEPKKLI 523

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +Y    L R YPKG RIDSSNYNP   W  G Q+VALN+QTP + M +N G F  NG CG
Sbjct: 524  EYSNKFLVRTYPKGSRIDSSNYNPTKGWVYGCQIVALNFQTPGEMMDINDGMFALNGKCG 583

Query: 1047 FILKPQFMFEEGYNPCD-KKSIEGKVKPVTVMLRVIGARHLCKTGRGTA--SPFVEVEII 1103
            ++LKP+ +    ++P +  KSI G  K   V +++I    L K  +      P++ + I 
Sbjct: 584  YVLKPECLRSGNFDPQNIDKSINGVCK---VFIKIISGHLLPKASKDETIPDPYIRINIH 640

Query: 1104 GADYDSGV-KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
            G   D  + K +TK V  NG NP WN+  +F++  PELA IRF + D D+ G  +FIGQ 
Sbjct: 641  GIPKDEVLGKFITKKVKRNGFNPQWNEDFQFDLYAPELAHIRFALCDSDM-GVDDFIGQY 699

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            + P   +R GYR VPL       ++ ++ +V +
Sbjct: 700  SIPFSAIRTGYRRVPLLKRSGHPIKNASFLVFI 732


>UniRef50_P40977 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1; n=1; Schizosaccharomyces pombe|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1 - Schizosaccharomyces pombe (Fission
           yeast)
          Length = 899

 Score =  212 bits (517), Expect = 6e-53
 Identities = 128/390 (32%), Positives = 201/390 (51%), Gaps = 37/390 (9%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           L + D+KE+R G+ ++++    + +   E  + FTI Y  + KL+    ++ T      W
Sbjct: 206 LCVDDIKEIRQGRDARNYREQYKISSENEK-RWFTIIYCADNKLKAMHMISPTLDAHNQW 264

Query: 130 VKGV----LYLIAEAVSA------------SYPLQIERWLRKEFYSIENSHEKITLKEVK 173
           +  +     Y + E +               Y   +  W + E    +    ++ L +V 
Sbjct: 265 IMALEGLKTYRLNEFIIGLNLVCHQGEKMIDYSENLNPWEKLE----KEQSAQLDLGDVH 320

Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYC 233
                ++   S   L + FQ  D +  G++ F++F   +  L+   + + DIF +Y+   
Sbjct: 321 RMCQMLHLNASMEFLEETFQKADADHSGKLSFEEFQH-FVSLLKTRSEIVDIFKEYT--- 376

Query: 234 SNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293
           S    ++L +F++FL   Q   L  D ++       Y+     D  +    L EF   L 
Sbjct: 377 SGSDKMSLEQFRHFLSTSQKARLDSDSIRTL-----YVSFCSND--DSKMGLIEFTSFLL 429

Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353
           S  NS        V QDM+RPL+ Y ISSSHNTYL G QF  ESS+E Y+R L+ GC+CI
Sbjct: 430 SPHNS----PVVPVIQDMSRPLNEYLISSSHNTYLLGKQFGGESSIEGYIRSLQRGCKCI 485

Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413
           E+DCWDGP+G P + HGHT T+ I+F DV+  I+++AF+ S YPL +S+E +C   QQR+
Sbjct: 486 EIDCWDGPNG-PVVCHGHTFTSMIKFNDVIDAIRKYAFVVSPYPLFISLEIHCCPDQQRQ 544

Query: 414 MASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           M S  +  FGD L++ P+  NE+ LPSP D
Sbjct: 545 MVSYMKQAFGDTLVMKPVTANESVLPSPED 574



 Score =  108 bits (259), Expect = 1e-21
 Identities = 75/268 (27%), Positives = 131/268 (48%), Gaps = 13/268 (4%)

Query: 934  IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQL 993
            I +E+  L  Y RS+ F    L  +   Y+ + SF E   ++   +       K++   L
Sbjct: 634  IVQELQQLAPYARSLKFRNFSLP-ESKTYSHIFSFSERTIKK-HGKAMVPRLSKHNLRYL 691

Query: 994  SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053
             R+YP   R+ S+N+NP  +W  G QMVALN+QT D  +Q+N   F  +   G++LKP  
Sbjct: 692  CRVYPGPLRVGSTNFNPQVYWRLGVQMVALNWQTYDTGLQINDALFIADPPTGYLLKPPC 751

Query: 1054 MFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRGTASPFVEVEIIGADYDS 1109
                G    +    EG  + + + + VI  + L +    +   T SP+VE+++   + +S
Sbjct: 752  QRIIGTTVGE----EGLPRKIKLTIDVISGQQLRRARELSNSETLSPYVEIQVHSME-ES 806

Query: 1110 GVKLVTKTVSDNGLNPLWNDICEFE--VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
              +  +K V +NG  P W +   +E  +++   ++IRF+V      G  +     T P+ 
Sbjct: 807  PFRWCSKVVHENGFRPFWGETMVYESIISDDFYSMIRFLVHHRGSNGNDSIFANFTCPID 866

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHL 1195
             L++GYR + L +   E L  S+L + +
Sbjct: 867  RLQQGYRHIRLLDMQGENLLFSSLFLKI 894


>UniRef50_Q9UPR0 Cluster: Inactive phospholipase C-like protein 2
           (Phospholipase C epsilon 2) (Phospholipase C-L2)
           (PLC-L(2)); n=58; Eumetazoa|Rep: Inactive phospholipase
           C-like protein 2 (Phospholipase C epsilon 2)
           (Phospholipase C-L2) (PLC-L(2)) - Homo sapiens (Human)
          Length = 1127

 Score =  211 bits (515), Expect = 1e-52
 Identities = 141/453 (31%), Positives = 231/453 (50%), Gaps = 27/453 (5%)

Query: 2   KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    ++ I  A   I+ +  GS + K     R   R   +  +   + W     
Sbjct: 120 KTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWE---- 175

Query: 61  PQRQGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119
           P ++  E A +DI+ +KEVRTGK++ D  R    + ++     F++ YG  ++      V
Sbjct: 176 PSKKDSEKAKIDIKSIKEVRTGKNT-DIFRSNGISDQISEDCAFSVIYGENYE--SLDLV 232

Query: 120 AQTDKECEAWVKGVLYLIA------EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEV 172
           A +      WV G+ YLI+      + + +S       W+ + F  I+ ++   ITL   
Sbjct: 233 ANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNA 292

Query: 173 KAFLPKINCKISTSKLRDVFQDV--DTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFDKY 229
              +  +N  + TSK+   F+++    +K G E+  ++F  ++ +L        +I+   
Sbjct: 293 VQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELC----TRPEIYFLL 348

Query: 230 SVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEF 288
             + SN   +  ++   FL  EQ     ++E+   + I  Y  +P ++  E  + ++  F
Sbjct: 349 VQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF 405

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
              L S    I+D ++ KV QDM +PLSHY+I+SSHNTYL  DQF   S +  Y+R L+ 
Sbjct: 406 TNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKM 465

Query: 349 GCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSL 408
           GCR +ELD WDGPD  P IY GHT+T++I F  V+  I ++AF  SEYPLIL +E++CS+
Sbjct: 466 GCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSI 525

Query: 409 PQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
            QQ+ M    + + GD L     +  E+ LPSP
Sbjct: 526 KQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSP 558



 Score =  196 bits (478), Expect = 3e-48
 Identities = 109/275 (39%), Positives = 164/275 (59%), Gaps = 11/275 (4%)

Query: 930  RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            + +++ KE+S+L+  C+SV F   ++  +   Y E+ SF E  A +  ++    F V Y+
Sbjct: 610  KRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDF-VNYN 668

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
               L+R++P   RIDSSN NP  FW CG Q+VA+N+QTP   M +N+G F+QNG CG++L
Sbjct: 669  KRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVL 728

Query: 1050 KPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEI 1102
            +P  M EE   ++   K S+ G V P  + +++I  ++  K  G G       P+V VEI
Sbjct: 729  RPAIMREEVSFFSANTKDSVPG-VSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEI 787

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
             G   D   +  TKTV  NG  P++++  EF++  PELA++RFVV D+D  G+  FIGQ 
Sbjct: 788  HGIPADCAEQR-TKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQY 845

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            T P  CL+ GYR VPL +   E L  ++L VH++I
Sbjct: 846  TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI 880


>UniRef50_A7SDH9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 665

 Score =  210 bits (513), Expect = 2e-52
 Identities = 116/350 (33%), Positives = 185/350 (52%), Gaps = 21/350 (6%)

Query: 95  KRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLR 154
           K+     C ++ +G +   R    VA++ +    W+ G+  LI      +       WL 
Sbjct: 8   KKYSLDTCISVKFGAD---RSLDLVAKSVETANLWLVGLQTLINNQSKCT-------WLI 57

Query: 155 KEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGF--DDFAVL 211
             F   + N   ++ L EV   L  +N  I+   ++  F+ V  +   E     ++FA  
Sbjct: 58  DAFEKFDKNKDGELGLSEVTKLLNALNVNITPKTIKKRFR-VSEQAGAEAALNKEEFAEF 116

Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271
           + K I   + + +I +K++   S    + + + Q FL  +    +            +  
Sbjct: 117 F-KAIATRDEIVEIMNKFT---SGKAHMNVEDLQKFLYKQGVKEVSKQYCDIIISTYEPT 172

Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331
            + QRD       +      L SK+  I+D+ +DKV QDM +PLSHY+I+SSHNTYL  D
Sbjct: 173 EEGQRD---KQLGIDGLTNYLLSKEGDIFDTAHDKVYQDMRQPLSHYFIASSHNTYLMED 229

Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAF 391
           Q    SS++AY+     GCRC+ELDCWDG +G P +YHGHTLT+KI+F D+++ + EHAF
Sbjct: 230 QLKGPSSVDAYINAFNKGCRCVELDCWDGDNGDPIVYHGHTLTSKIKFKDIIQAVAEHAF 289

Query: 392 ITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
             S+YP+ILS+E++C++  QR++A   +++ GD L   P+D   TSLPSP
Sbjct: 290 KVSDYPVILSLENHCNIENQRKIAEHLENILGDKLFKDPVDTALTSLPSP 339



 Score =  201 bits (490), Expect = 1e-49
 Identities = 116/277 (41%), Positives = 168/277 (60%), Gaps = 13/277 (4%)

Query: 929  ERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVK 987
            E+  ++AKE+S  + Y  SV F N E  +     Y +MSSF E+K   L +Q +   FV+
Sbjct: 394  EKKVKLAKELSRCVNYISSVGFKNFEHSKENAKFY-QMSSFVESKVATL-AQNKAAGFVE 451

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047
            Y+T QLSR YP G R+DSSNYNP   WN G Q+VALNYQT  + M +N G+F++N   G+
Sbjct: 452  YNTRQLSRTYPAGSRVDSSNYNPQVAWNVGCQIVALNYQTDGEYMHLNQGRFRENKRAGY 511

Query: 1048 ILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRG-TASPFVEV 1100
            +LKP +M      +NP + KS  G VK   ++++VI  + L K    + +G    P+VEV
Sbjct: 512  VLKPAYMRNPDIKFNPNNPKSCPG-VKKKLLIIQVISGQQLPKPQGSSSKGEVIDPYVEV 570

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            +I G + DS     TK + DNG NP+WN+  +  +  PELA++RF V DED+ G+ +FIG
Sbjct: 571  KIYGVNSDS-ADFKTKVIKDNGFNPVWNEEIKKLLYVPELAMLRFCVYDEDV-GKDDFIG 628

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            Q + P+  LR GYR + L +   E L  ++L VH+ +
Sbjct: 629  QFSLPITSLRTGYRHIHLLDIKGEPLPHASLFVHVML 665


>UniRef50_Q4RY83 Cluster: Chromosome 3 SCAF14978, whole genome shotgun
            sequence; n=2; Tetraodontidae|Rep: Chromosome 3
            SCAF14978, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 806

 Score =  207 bits (505), Expect = 2e-51
 Identities = 107/274 (39%), Positives = 163/274 (59%), Gaps = 10/274 (3%)

Query: 928  MERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            M    R++KE+SD ++YC+SV F + +  RI    Y E++SF E+KA + + ++    FV
Sbjct: 537  MRSKQRLSKELSDCVVYCKSVHFRSFKHSRIHSKFY-EVASFTESKARKHL-REAGAEFV 594

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             +++ QL+R+YP G R DSSN+NP   WN G Q+VALN+QT  + M +N G F+QNG CG
Sbjct: 595  YHNSRQLTRVYPSGFRTDSSNFNPQEMWNAGCQIVALNFQTAGEGMDLNDGLFRQNGNCG 654

Query: 1047 FILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG---RGTASPFVEVE 1101
            ++LKP FM   E+ ++P +        KP+ + ++VI  + L K          P V VE
Sbjct: 655  YVLKPSFMRTAEKRFDP-ETPHKRDSYKPIVLTIQVISGQQLPKVNIKEDSIVDPLVRVE 713

Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQ 1161
            I G   D   K  T+ + +NG NP+W D   F +  PELA++RFVV+D D     +F+GQ
Sbjct: 714  IYGVPLDQ-AKQETRYIENNGFNPVWYDTLRFTIHTPELAMVRFVVEDYDKTSRNDFVGQ 772

Query: 1162 ATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
             T PL C+++GYR + L +     +  ++L VH+
Sbjct: 773  YTLPLSCMQQGYRHIHLLSKDGTSIPPASLFVHI 806



 Score =  200 bits (488), Expect = 2e-49
 Identities = 101/252 (40%), Positives = 150/252 (59%), Gaps = 7/252 (2%)

Query: 193 QDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252
           Q  D  + G +  D+F VL+ K++    +V  +F +YS   ++G  ++  + ++FLR+EQ
Sbjct: 237 QMADKSQSGTLEGDEF-VLFYKMLTQREDVLKVFQEYS---ADGQKLSQADLEDFLREEQ 292

Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312
            +  GD +  A Q I  Y       +     T   F+  L S + SI++     + QD+ 
Sbjct: 293 FEE-GDIQHHAKQLIERYEPSDTAKLLNA-MTFDGFLMYLGSTEGSIFNPDRRGIFQDLG 350

Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT 372
           +PL HY+I+SSHNTYL  DQ    SS+E Y+R L  GCRC+E+DCWDG +G P +YHGHT
Sbjct: 351 QPLCHYFIASSHNTYLMEDQLRGHSSVEGYIRALSRGCRCVEVDCWDGANGEPIVYHGHT 410

Query: 373 LTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432
            T+KI F DV+  +  +AF  SEYP+ILS+E++C + QQ+ MA     + GD LL + ++
Sbjct: 411 FTSKILFKDVVGAVANYAFKVSEYPVILSVENHCGVEQQKVMAQHLNHILGDKLLKNTLN 470

Query: 433 -KNETSLPSPHD 443
            K  T LPSP D
Sbjct: 471 GKAPTGLPSPED 482



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 48/272 (17%), Positives = 114/272 (41%), Gaps = 22/272 (8%)

Query: 14  IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73
           I E D L S +  GS + K   R   ++R   ++ +    +W +  + +         + 
Sbjct: 6   IREDDNLQSMLV-GSVMRKIKSRTWKKQRYFKLQEDC-MTIWYK--SKKAGNSHSTFSVS 61

Query: 74  DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133
           DV+ +R G  S+      +E     + +CFT+ + +  +      VA++ +E ++W++G+
Sbjct: 62  DVEAIREGHQSEVLLSIADE---FPADRCFTLVFRS--RRGNLDLVAESAEEAQSWIRGI 116

Query: 134 LYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQ 193
             L+    +     +++ W    F+ + N   ++ +  +      ++  +    + D F+
Sbjct: 117 RKLVENLENMGEREKLDHW----FHGLTNVSNRV-IDWLANLGEDLSSSVLIRWISDWFK 171

Query: 194 DVDTEKRGEIGFDDFAVLYQKLIFD--ENNVQDIFDKYSVYCSNGTTI-TLR-----EFQ 245
             D    G + F +   L + +  D  E++   +F       S G ++ T++     +F+
Sbjct: 172 KADKNNDGRMNFKEVRDLLKMMNVDMSEHHAHRLFTVRPSDLSGGHSLDTVQRVPQPKFR 231

Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD 277
           +F   +  D      ++  +F+  Y    QR+
Sbjct: 232 SFSLTQMADKSQSGTLEGDEFVLFYKMLTQRE 263


>UniRef50_UPI000069E9FD Cluster: phospholipase C, delta 4; n=1;
            Xenopus tropicalis|Rep: phospholipase C, delta 4 -
            Xenopus tropicalis
          Length = 781

 Score =  205 bits (500), Expect = 7e-51
 Identities = 112/272 (41%), Positives = 158/272 (58%), Gaps = 11/272 (4%)

Query: 933  RIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            R++  +SD +IYC+SV F + +  R    +Y EMSS  E KA +L+ +  N F V+++  
Sbjct: 510  RLSHLLSDCVIYCKSVPFVSFQHSRAHYTLY-EMSSVTEYKARKLVREPGNDF-VRHNAW 567

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
            QL R+YP G R DSSNYNP   WN G QMVALN+QT    M +N G F+QN  CG++LKP
Sbjct: 568  QLMRVYPTGLRTDSSNYNPQEMWNVGCQMVALNFQTAGVEMDLNDGLFRQNARCGYVLKP 627

Query: 1052 QFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVEIIGA 1105
             FM   E  +NP   +S EG   PV + + VI A+ L K           PFV VEI G 
Sbjct: 628  SFMRHVETTFNPDQPQSTEG-YSPVNLSILVISAQQLPKVENSKEGSIVDPFVRVEIFGV 686

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D   K  TK + +NG NP+W +   F++  PELAL+RFVV+D D     +F+GQ T P
Sbjct: 687  PIDQ-TKQETKYIENNGFNPMWYETLHFKIHVPELALVRFVVEDYDKTSRNDFVGQYTLP 745

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
               ++ GYR + L +    ++  +++ VH+ +
Sbjct: 746  FKSIKSGYRHIHLLSRDGTKMPPASVFVHVRV 777



 Score =  194 bits (472), Expect = 2e-47
 Identities = 120/365 (32%), Positives = 191/365 (52%), Gaps = 19/365 (5%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECEA 128
           + I D++ VR G  S+  +   +E K      CFTI ++G    L     VA T +E + 
Sbjct: 7   VSISDIETVREGHQSEVLQSIADEFK---PELCFTIVFHGRRANL---DLVANTPEEAQC 60

Query: 129 WVKGVLYLIAEAVSASYPLQIE----RWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKI 183
           W++G+  LI    +      ++    RW+   F   + N   ++  KEV+  L  +N  +
Sbjct: 61  WIQGLEKLIETVTNMDQKDLLDQYPFRWICDWFQKADKNKDGRMNFKEVQDLLKMMNVDM 120

Query: 184 STSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLRE 243
           S      +FQ  D  + G +  ++F VL+ K +   + V  IF  +S    +G  +TL E
Sbjct: 121 SEHHAYRLFQMADKSESGTLEGEEF-VLFYKALTQRDEVLKIFQDFS---KDGKKLTLLE 176

Query: 244 FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
           F +FL+  Q +    +E+      R    D  + ++    ++  FV  L S + SI++  
Sbjct: 177 FVDFLQQGQLEEENTEELAMDLIARYEPSDTAKKLHA--MSIDGFVMYLCSPEGSIFNVA 234

Query: 304 YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG 363
           ++++ QDMT+PL HY+ISSSHNTYL  DQ   +SS+E Y+R L+ GCRC+E+D WDGP+G
Sbjct: 235 HEQLYQDMTQPLCHYFISSSHNTYLMEDQIRGQSSVEGYIRALKRGCRCVEVDTWDGPNG 294

Query: 364 TPFIYHGHTLTTKIRFMDVLRTIKEHAF-ITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            P +YHG T T+KI F DV+  I ++AF ++   PLI  I    ++    + AS  +   
Sbjct: 295 EPIVYHGRTFTSKILFKDVISAINKYAFRVSGLLPLIYMIRAIGTMKGGGKFASFARAFL 354

Query: 423 GDLLL 427
           G  LL
Sbjct: 355 GPRLL 359


>UniRef50_Q86YW0 Cluster: Phospholipase C zeta 1; n=7; Eutheria|Rep:
            Phospholipase C zeta 1 - Homo sapiens (Human)
          Length = 608

 Score =  196 bits (479), Expect = 2e-48
 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 338  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 396

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 397  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 454

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 455  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 510

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 511  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 569

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 570  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 604



 Score =  196 bits (478), Expect = 3e-48
 Identities = 102/277 (36%), Positives = 161/277 (58%), Gaps = 8/277 (2%)

Query: 166 KITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI 225
           KI L++ +  L K++ + S   ++ +F+D D  K+G I  ++F  +Y ++I     + +I
Sbjct: 18  KINLEKTQRLLEKLDIRCSYIHVKQIFKDNDRLKQGRITIEEFRAIY-RIITHREEIIEI 76

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPY-FT 284
           F+ YS    N   +       FL  EQ+       + A + I+ Y  +P  ++ + +  +
Sbjct: 77  FNTYS---ENRKILLASNLAQFLTQEQYAAEMSKAI-AFEIIQKY--EPIEEVRKAHQMS 130

Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344
           L  F   + S++  ++ ++  KV QDMT PL+ Y+ISSSHNTYL  DQ    S L  YV 
Sbjct: 131 LEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVS 190

Query: 345 CLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404
            L  GCRC+E+DCWDG    P +YHG+TLT+K+ F  V++ I ++AF+TS+YP++LS+E+
Sbjct: 191 ALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLEN 250

Query: 405 NCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           +CS  QQ  MA   Q  FG+ LL   +D    +LPSP
Sbjct: 251 HCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 287


>UniRef50_Q08AQ7 Cluster: PLCZ1 protein; n=19; Amniota|Rep: PLCZ1
            protein - Homo sapiens (Human)
          Length = 415

 Score =  196 bits (479), Expect = 2e-48
 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K  R  +IA  +SDL+IY ++  F + +  R+    +NE +S  ET+A +L   + + F 
Sbjct: 145  KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 203

Query: 986  VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              +HT + ++RIYPK  R DSSN+NP  FWN G QMVALN+QTP  PM +  GKF  NGG
Sbjct: 204  --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 261

Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100
             G+ILKP F+ E    +NP + K  EG   P+T+ +R+I    L  T          V +
Sbjct: 262  SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 317

Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            E+ G   D  +K  T+ +  N  +P WN+   F +  PELALIRFVV+ + +     F+G
Sbjct: 318  EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 376

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            Q T PLLC+ KGYR +PL +   E LE ++L V++
Sbjct: 377  QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 411



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 24/51 (47%), Positives = 33/51 (64%)

Query: 391 FITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           F TS+YP++LS+E++CS  QQ  MA   Q  FG+ LL   +D    +LPSP
Sbjct: 44  FKTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 94


>UniRef50_UPI0000EB12AF Cluster: phospholipase C-like 3; n=1; Canis
            lupus familiaris|Rep: phospholipase C-like 3 - Canis
            familiaris
          Length = 1206

 Score =  195 bits (476), Expect = 5e-48
 Identities = 112/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++ +E+SDL++Y  SV    + +   G   N +S F ET+A +++ Q+   F +
Sbjct: 218  RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 274

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             Y+  QL+RIYP   RIDSSN+NP+P+WN G Q+VALNYQ+  + MQ+N  KFK NG CG
Sbjct: 275  -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKTNGNCG 333

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKPQ M +  +NP     +    K   ++L+VI  + L K        RG    PFVE
Sbjct: 334  YVLKPQQMCKGTFNPYSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 392

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F V  P++AL+RF+V D D  G  +F+
Sbjct: 393  VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPDIALVRFLVWDHDPIGR-DFV 450

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH++I
Sbjct: 451  GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 483



 Score = 49.2 bits (112), Expect = 7e-04
 Identities = 23/47 (48%), Positives = 34/47 (72%), Gaps = 1/47 (2%)

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET-SLPSP 441
           +P+ILSIE++CS+ QQR++A   + +FGD L +  +D  ET  LPSP
Sbjct: 14  FPVILSIENHCSVQQQRKIAQYLKGIFGDKLDLSSVDTGETKQLPSP 60


>UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholipase
           c epsilon; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to phospholipase c epsilon - Nasonia vitripennis
          Length = 1801

 Score =  194 bits (473), Expect = 1e-47
 Identities = 103/236 (43%), Positives = 140/236 (59%), Gaps = 8/236 (3%)

Query: 211 LYQKLIFDENNVQDIFDKYS-VYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269
           L++K IFD      I +  S V  S    ITL  F  FL   Q + L DDE++A   I+ 
Sbjct: 739 LHKKQIFDAIAAASIVNNCSGVDTSKSQVITLATFTKFLESRQQEKLSDDEIKA--LIKR 796

Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ-DMTRPLSHYWISSSHNTYL 328
           +  DP     +   +   F   +  K N  + ++Y    + +M +P+S Y+I+SSHNTYL
Sbjct: 797 HEPDPALRT-QWCLSFEGFARYMMDKDNYAFPNEYALPAECEMQQPMSQYYIASSHNTYL 855

Query: 329 TGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKE 388
           TG Q   ESS++ Y + L +GCRC+ELDCWDG DG+P IYHGHT TTKI F  V+  I  
Sbjct: 856 TGHQLKGESSVQLYSQVLLTGCRCVELDCWDGDDGSPLIYHGHTFTTKIPFRSVVEAIDR 915

Query: 389 HAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL---VHPMDKNETSLPSP 441
            AF++S YP+ILSIE++CS  QQ RMA  FQ VFG+ L+   +   D ++  LPSP
Sbjct: 916 SAFVSSPYPVILSIENHCSQSQQARMAQIFQSVFGEKLVTKFLFDSDFDDPQLPSP 971



 Score =  154 bits (374), Expect = 1e-35
 Identities = 91/237 (38%), Positives = 133/237 (56%), Gaps = 14/237 (5%)

Query: 964  EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023
            + SS  E+ A+++  +Q     + +  TQL R YP G RIDSSN+NPV FW  G QMVAL
Sbjct: 1192 QTSSLNESAAKKICRKQP-LGVLGHAETQLIRTYPAGMRIDSSNFNPVIFWAFGIQMVAL 1250

Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE------GYNPCDKKSIEGKVKPVTVM 1077
            NYQT D  + +N   F+QNG CG++ KP  M+++       +NP DK+  +G +    + 
Sbjct: 1251 NYQTDDAALHLNAAMFEQNGQCGYVRKPSVMWDKKHMMYRRFNPWDKE-FDG-LHSAHLT 1308

Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137
            L +I  +++  +    +S +VE+E++G   D   K  TK +  N LNP+WND   F+V  
Sbjct: 1309 LSIISGQYVSPSNL-LSSTYVEIELVGIPIDC-AKHKTKVIQGNSLNPIWNDKFCFQVMF 1366

Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
             +LA +RF + D       + I Q   PL CLR GYR V L    +  L LSTL ++
Sbjct: 1367 KDLAFLRFGIMDA---SSHHPIAQRVLPLKCLRPGYRHVRLRTMKNRALALSTLFIY 1420


>UniRef50_Q4RKI8 Cluster: Chromosome 21 SCAF15029, whole genome
            shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 21
            SCAF15029, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 955

 Score =  193 bits (471), Expect = 2e-47
 Identities = 111/272 (40%), Positives = 160/272 (58%), Gaps = 9/272 (3%)

Query: 932  WRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            +++ KE+SDL+  CRSV F       K     E+ SF ET A RL ++    F V ++  
Sbjct: 555  FQLLKELSDLVTLCRSVRFVDFPTSSKSQKSWELCSFHETLALRLATESPRDF-VNHNKH 613

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             LSR+YP   RIDSSN NP   W CG Q+V++N+QT    M +N   F+QNG CG++L+P
Sbjct: 614  FLSRVYPCPMRIDSSNMNPQDLWKCGCQIVSMNFQTAGLMMDLNTAWFRQNGNCGYVLRP 673

Query: 1052 QFMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEIIGA 1105
              M +E  Y   D +     V P  + ++VI  ++L K  G G       P+V VEI G 
Sbjct: 674  AIMRQEVSYFSADTRDTVPGVSPQLLHVKVISGQNLPKPRGSGAKGDVVDPYVYVEIHGI 733

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              D  ++  T+TV+ NG NP++++  EF++  PELA++RFVV D+D  G+  FIGQ T P
Sbjct: 734  PADC-MERRTRTVTQNGDNPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQYTIP 791

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L C++ GYR VPL +   EEL  + L VH+++
Sbjct: 792  LECIQPGYRHVPLQSLTGEELLHARLFVHVAL 823



 Score =  188 bits (458), Expect = 8e-46
 Identities = 140/511 (27%), Positives = 237/511 (46%), Gaps = 47/511 (9%)

Query: 2   KSVCFNGA--KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRIN 59
           K+V F+ +  + ++   AD + S +E GS + K     R  +R   +      + W    
Sbjct: 12  KTVSFSSSLSEKKISSAADCIYSMVE-GSELKKIRTNSRVYQRYYLLDTGLQALCWE--- 67

Query: 60  APQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119
             +++  +  + +  ++EVRTG++++ F R     +++     F+I YG  ++      V
Sbjct: 68  PSKKESDKARISLDSIREVRTGRNTETF-RTSGVYEQISEDCAFSIIYGELYE--SLDLV 124

Query: 120 AQTDKECEAWVKGVLYLIAEAVSASYPLQIER------WLRKEFYSI------ENSHEKI 167
           A + +    WV G+ YL+     A   L   +      WL + F +       +N  E I
Sbjct: 125 ANSAEVANIWVTGLRYLMQYGKHALDMLASSQDSLRLVWLEQLFSAAVDPNGKDNGEESI 184

Query: 168 TLKEVKAFLPKINCKISTSKLRDVFQDVDT--EKRGEIGFDDFA---------------- 209
           +L+     +   N  +S SK+   F+++    ++   +  D+ +                
Sbjct: 185 SLQSAVRLIKSANPGVSGSKVEQRFKELQRVRDRMCSLALDNGSEAKELKENKRLPMGKR 244

Query: 210 --VLYQKLI---FDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS 264
             V+ Q+ I    D     +I+     + SN   +  ++   FL  EQ   L  +E    
Sbjct: 245 EQVIKQEFIEVFLDFCTRPEIYFLLVQFSSNKEFLDTKDLMRFLEAEQGMALVSEETSL- 303

Query: 265 QFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSH 324
           Q I+ +    +    + Y +L  F   L S +  ++D ++D V QDM++PLSHY+I SSH
Sbjct: 304 QLIQAH-EPSEEGRQQGYLSLDGFTSYLTSAECHLFDREHDAVCQDMSQPLSHYYICSSH 362

Query: 325 NTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLR 384
           NTYL  DQ    S +  Y+R L+ GCRC+E+D WDG DG P +  GHTL+  +    VL 
Sbjct: 363 NTYLIEDQIRGPSDISGYIRALKMGCRCVEVDVWDGSDGEPVVCTGHTLSPPLALHSVLE 422

Query: 385 TIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDX 444
            I++ AF+ S+YPLI+ IE++CS  QQ+ M      +FGD L   P ++ ++ LPSPH  
Sbjct: 423 AIEKCAFVASDYPLIVCIENHCSYQQQQVMCQHLTRIFGDKLYTDPPNQEDSYLPSPHAL 482

Query: 445 XXXXXXXXXXXPEGAEESSFAVRQE-EGKDL 474
                        G E     V +E EG ++
Sbjct: 483 RHRIILKGKKLGPGLEAEDGEVSEEDEGAEM 513


>UniRef50_A0BLC4 Cluster: Chromosome undetermined scaffold_114,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_114,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 825

 Score =  192 bits (469), Expect = 4e-47
 Identities = 107/270 (39%), Positives = 159/270 (58%), Gaps = 19/270 (7%)

Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224
           E+ITLK++K  LP+++  I+  +L+ +F   D E++G I   D+  L ++L+ +++ V+ 
Sbjct: 154 EQITLKQIKGMLPQLS--ITKQELKTLFNQFDLERKGYISNSDYQDLLKRLM-NQDFVRF 210

Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFT 284
           +FD+Y++   N      +EF  FL  EQ       + Q     R + +          F+
Sbjct: 211 LFDRYAIQQMNK-----QEFIKFLTSEQSPY----QKQCEDAFRLFAKQDGNS-----FS 256

Query: 285 LS--EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342
           LS  EF+  L S  N ++D Q  +V Q    PL+ YWI+SSHNTYL GDQ +SESS++AY
Sbjct: 257 LSFLEFLNYLLSTYNQLFDYQKTQVYQSEDFPLTDYWINSSHNTYLMGDQLTSESSIQAY 316

Query: 343 VRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402
           +   + GCRC+ELDCWDG +  P IYHG T+T+KI F  V+ TIKE+ F  S+YPLILS+
Sbjct: 317 INAFQKGCRCVELDCWDGDNNQPIIYHGFTMTSKISFESVIETIKEYGFKYSKYPLILSL 376

Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432
           E +C + QQ  M    +      LL+ P D
Sbjct: 377 EVHCCVKQQDVMTDILKTYLNVNLLLLPDD 406



 Score =  144 bits (348), Expect = 2e-32
 Identities = 83/218 (38%), Positives = 123/218 (56%), Gaps = 11/218 (5%)

Query: 982  NTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ 1041
            N   + YH    +RIYP G R+DSSNY+P+P +N GSQ+VALN+QT D PM +NM KF +
Sbjct: 612  NENLLDYHRKYFTRIYPSGSRVDSSNYDPIPAFNSGSQIVALNFQTNDMPMLINMCKFME 671

Query: 1042 NGG--CGFILKPQFMFEEGYNPCDK-KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFV 1098
            NGG   G++LKPQ+M  +G    ++  SI+      T+ + V     L        +P +
Sbjct: 672  NGGIESGYVLKPQWMRSDGKKKINEFTSIQ---LSFTLSILVGYNLRLLNDQNAKVNPSI 728

Query: 1099 EVEIIGADYD-SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157
            ++ I G   D    K    T+S NGLNP +N I ++ +  P+LA + F V D       +
Sbjct: 729  KISIRGLLQDEQNNKPQIATISQNGLNPQFNFIYKYNIRCPDLAFLIFEVLD----ASKS 784

Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            F+G +  PL C+  GYR+V L + + + L  S L+VH+
Sbjct: 785  FLGWSAIPLSCMSYGYRAVQLLSQYLKPLPKSCLLVHV 822


>UniRef50_Q5CR08 Cluster: Phospholipase C, delta 1 ortholog with 2
           EF hands plus phospholipase C domain plus C2 domain;
           n=2; Cryptosporidium|Rep: Phospholipase C, delta 1
           ortholog with 2 EF hands plus phospholipase C domain
           plus C2 domain - Cryptosporidium parvum Iowa II
          Length = 883

 Score =  192 bits (468), Expect = 5e-47
 Identities = 116/334 (34%), Positives = 179/334 (53%), Gaps = 13/334 (3%)

Query: 156 EFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFA-VLYQK 214
           E   ++NS   I+  E+     ++   +S      +F + D +  G + + +F  +L Q 
Sbjct: 220 ELSDLDNSGS-ISFTELMRLTKRLQMPVSKDYTHALFCEYDNDNNGALDYKEFRNLLTQL 278

Query: 215 LIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDP 274
           LI  E  ++D+FD+Y    +N   +   +F+NFL D Q     D        +   L   
Sbjct: 279 LILPE--LRDLFDEYKDPDTN--VMGANKFRNFLIDVQGM---DPSNSLESLVNAVLNMK 331

Query: 275 QRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334
           +  I     T   F  ++ S+ NS +D     V Q M  P+SHYWI+SSHNTYLTGDQ +
Sbjct: 332 EPFIERGGITEIGFNILMSSEFNSAFDPLKRDVYQSMDEPISHYWIASSHNTYLTGDQLT 391

Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITS 394
           S+S +  Y+  L  GCRC+ELD W+GPDG+P IYHGHTLT+K+ F DV+R  K++AF  S
Sbjct: 392 SKSEIGQYITVLLQGCRCVELDVWNGPDGSPIIYHGHTLTSKVYFEDVIRACKDYAFQIS 451

Query: 395 EYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXX 454
            YP+ILS+E + S  Q+ ++A    +V GD L + P D ++  LP+P++           
Sbjct: 452 PYPIILSLEMHASDKQREKVAEIILNVLGDSLYIPPNDGSD-RLPTPNE-LKYKFLVKAK 509

Query: 455 XPEGAEESSFAVRQEEGKDLDLRNSIKNGILHLE 488
            P+  E+ SF +R     + D +N +   IL ++
Sbjct: 510 VPK--EDISFDLRAGVINEDDEKNDLNPDILEVD 541



 Score =  133 bits (322), Expect = 2e-29
 Identities = 82/260 (31%), Positives = 138/260 (53%), Gaps = 27/260 (10%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            + S  ETK  RL ++  +    K+H   L R+YP G RI SSNYNP+  W+ G+Q+VALN
Sbjct: 593  IGSLVETKFLRL-AKDSSMSLAKFHQDHLCRVYPSGTRISSSNYNPLIPWSYGAQIVALN 651

Query: 1025 YQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEGY--------NPCDKKSIEGKVKPV 1074
            YQ     + +N G+F+QNGG   G++LKP+   ++ +        NP +   +   + PV
Sbjct: 652  YQAVGTALLLNEGRFRQNGGSKSGYVLKPKMCLKKCFDGRVFDPMNPLETLEL-FDIPPV 710

Query: 1075 TVMLRVIGAR----HLCKTGRGTA--------SPFVEVEIIGADYDSGVKLVTKTVSDNG 1122
             V ++++ A     +L +  RG A        SP++ + + G   +      T  +++NG
Sbjct: 711  RVCIQILSAHQLPDNLSQFSRGIAGLISGNKLSPYITISVFGGPSEEFKSYRTPVINNNG 770

Query: 1123 LNPLWNDIC--EFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180
             NP W ++    F V  PE+++I F V+  D   +  FI  A+ P+ CLR G R + L +
Sbjct: 771  FNPKWENLSPFTFNVLCPEISIINFEVKSSDSI-QSEFIAAASIPVSCLRPGLRWIQLFD 829

Query: 1181 AFSEELELSTLMVHLSIITD 1200
            A   +++   ++ ++SI T+
Sbjct: 830  ANFIDIQCCGILANISITTE 849


>UniRef50_Q4RSB2 Cluster: Chromosome 13 SCAF15000, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
            SCAF15000, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 551

 Score =  192 bits (467), Expect = 6e-47
 Identities = 110/269 (40%), Positives = 155/269 (57%), Gaps = 6/269 (2%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            +M  + +I K +SDL++Y RSV F +    R     Y E +S  E KA +L+ +     F
Sbjct: 282  RMTGSKKIVKALSDLVVYTRSVKFCSFTHSRDNQHSY-ENTSLEENKARKLL-KSSGADF 339

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            V ++   LSRIYP G R  SSNYNP  FWN G Q+VALN+Q+   PM +N G+F+ NGGC
Sbjct: 340  VGHNQRFLSRIYPAGSRTSSSNYNPQEFWNVGCQLVALNFQSLAAPMDLNDGRFQDNGGC 399

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-CKTGRGTASPFVEVEIIG 1104
            G++LKP  +        D +  + +V+PV ++L+VI   +L     R +  PFV+VEI G
Sbjct: 400  GYVLKPVVLM-SSQGCFDPRRSQRRVRPVHLLLKVISGSNLPILKSRKSLDPFVKVEIHG 458

Query: 1105 ADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATF 1164
               DS  K  T TV +N L+P W+    F+++ PEL LIRF V+D+       F+GQ T 
Sbjct: 459  IPSDSS-KQSTHTVKNNSLSPHWDAHMNFKISTPELCLIRFCVRDQTGLLSSEFVGQYTL 517

Query: 1165 PLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
            P   L KGYR VPL +     L+ ++L V
Sbjct: 518  PFTSLMKGYRWVPLWSRDGCSLDPASLFV 546



 Score =  185 bits (450), Expect = 7e-45
 Identities = 98/221 (44%), Positives = 132/221 (59%), Gaps = 4/221 (1%)

Query: 224 DIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYF 283
           DI   Y  Y S+ T ++      FL  EQ + L  DE    + I+ Y  +    I     
Sbjct: 14  DIQQLYQRYLSDAT-LSAANLLQFLHKEQKE-LTADEDTTKRLIQRYEIEHSA-IEAKSM 70

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
           T   F   + SK+  +++  +  V QDM +PLS Y+ISSSHNTYLTGDQ   +S L+AYV
Sbjct: 71  TFEGFFRYMESKECCVFNQAHTSVYQDMDQPLSSYFISSSHNTYLTGDQLVGKSHLDAYV 130

Query: 344 RCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIE 403
             LR GCRC+E+DCWDG D  P +YHG+TLTTKI F +V+ T+++HAF  S YP+ILS+E
Sbjct: 131 CALRKGCRCLEIDCWDGADMEPVVYHGYTLTTKILFKEVITTVEQHAFEKSPYPVILSLE 190

Query: 404 DNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET-SLPSPHD 443
           ++C   QQ  MA     + G+ LL  P+D   T  LPSP+D
Sbjct: 191 NHCCKEQQEIMAHYLVSILGEKLLRAPIDHPATGELPSPND 231


>UniRef50_UPI000023F2A0 Cluster: hypothetical protein FG05898.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG05898.1 - Gibberella zeae PH-1
          Length = 1111

 Score =  189 bits (460), Expect = 5e-46
 Identities = 129/442 (29%), Positives = 219/442 (49%), Gaps = 34/442 (7%)

Query: 24  IERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKS 83
           +  G  V K   + RP+R  L    E++++ W   + PQ+     +L + +++E+RTG  
Sbjct: 231 LRNGCPVKKVSKKSRPKRITLAYETESNKLSWDP-SRPQK-----SLHVDEIREIRTGTD 284

Query: 84  SKDFERWPEETKRLES--SKCFTIYYGT--EFKLRCASFVAQTDKECEAWVKGV------ 133
            + +      ++++E      FTI Y      K R    V         W + +      
Sbjct: 285 IQQYIHDYGLSEQIEFYFPVWFTIIYNVPESSKTRFLHIVTDNSNTLSLWTEFLDAMLRY 344

Query: 134 -LYLIAEAVSASYPLQIERW---LRKEFYSIENS--HEKITLKEVKAFLPKINCKISTSK 187
              L+   +S +     + W   + KEF     +   E++ +  VK     ++   S+S 
Sbjct: 345 RQQLMTSLMSFNDRAVAQYWQTEMAKEFGDQARTPDQEEMNIAGVKRVCQNLHIYSSSST 404

Query: 188 LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNF 247
           L   F   D+ +R ++ F +F    +++    N+VQ +    +     G  +TL EF  F
Sbjct: 405 LEVNFHLSDSRRRSKLNFREFKDFVRRMK-QRNDVQRVIRNIAANPEFG--LTLSEFLTF 461

Query: 248 LRDEQHDNLGDD----EVQASQFIRDYLRDPQRDIYEPYFTLSE--FVEMLYSKQNSIYD 301
           LRD+Q +++  +    E   S+F R Y R  + D+ E    ++E  FV  L S+ N +  
Sbjct: 462 LRDDQGEDVDSNRTAWEKLFSRFCRQY-RSTEADLPENVEIMTEAAFVAFLTSEDNEVIQ 520

Query: 302 SQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGP 361
            +   +  D  RP++ Y+ISSSHNTYL G Q + +SS+E Y+  L  GCRC+E+DCWDG 
Sbjct: 521 PEPQNIVLD--RPMNEYYISSSHNTYLLGRQVAGQSSVEGYISALARGCRCVEVDCWDGY 578

Query: 362 DGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDV 421
           +G P + HG T+TT I F +V+ TI ++AF+ S++PL +S+E +CS  QQ  M    ++ 
Sbjct: 579 NGQPEVNHGRTMTTSISFKEVMTTINKYAFVKSKFPLWISLEVHCSPAQQATMVEIIKES 638

Query: 422 FGDLLLVHPMDKNETSLPSPHD 443
           FG  L+   ++     LP+P +
Sbjct: 639 FGSRLVTETLEAFPDKLPTPSE 660



 Score =  111 bits (268), Expect = 8e-23
 Identities = 82/293 (27%), Positives = 143/293 (48%), Gaps = 30/293 (10%)

Query: 933  RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            +  K + DL +YC  V F+  + +  K   YN + SF E+   +    ++    +  H  
Sbjct: 769  KTVKVLGDLGVYCAGVKFSGFDTVDAKQ--YNHIFSFMESSFAKHSRAKDQKMALDIHNM 826

Query: 992  Q-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
            + + R+YP   RI S+N++P+ +W  G QM ALN+QT D  MQ+N   F      G++LK
Sbjct: 827  RYMMRVYPDRTRITSNNFDPLNYWRRGVQMAALNWQTFDLGMQLNRAMFDGKDSSGYVLK 886

Query: 1051 PQFMFEEGYNPCDKKSIEGKVK--PVTVMLRVIGARHLCKTGRGTAS----PFVEVEIIG 1104
            P  + +    P +    EGK +   ++  + VI A+ L +     A+    P+VEVE+  
Sbjct: 887  PAELRDIQVLPYNADIAEGKKERTVISFTIDVISAQQLMRPANLPANKSMDPYVEVEVFH 946

Query: 1105 A---------------DYDSGVKLVTKTVSDNGLNPLWNDICEFEVA--NPELALIRFVV 1147
            A               ++D+ +K  T  + +NG NPL++   ++ V   +P+L  +R+ V
Sbjct: 947  ANDKRDKKEADSNLVLEHDTPLKYQTDVIRENGFNPLFDRTMKYTVTTKHPDLIFVRWSV 1006

Query: 1148 Q---DEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            +   D + + E   +   T  L  L++GYR++PL N   ++   S L   + I
Sbjct: 1007 KLSNDGESYNERPAVATYTAKLTNLKQGYRTLPLLNHAGDQYLFSKLFCKIKI 1059


>UniRef50_A7RKT2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 433

 Score =  188 bits (459), Expect = 6e-46
 Identities = 110/242 (45%), Positives = 143/242 (59%), Gaps = 16/242 (6%)

Query: 215 LIFDENNVQD-IFDKYSVYCSNGTTITL--REFQNFLRDEQHDNLGDDEVQASQFIRDYL 271
           ++FD  N Q  +   Y+ Y  +   + L   EFQ FL  EQ ++L         +  D L
Sbjct: 162 MLFDSLNEQARLLSVYATYARSYPHLGLSPEEFQAFLAKEQKESLSLAMCAKLIYAHDKL 221

Query: 272 R----------DPQRDIYEPYF-TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWI 320
                      DP       +F +L  F+  L S+ NSI   +++KV QDM +PLS Y+I
Sbjct: 222 HTMFKRKCAGNDPDAFKRSKHFLSLHGFISFLRSQDNSIVKPEHNKVYQDMDQPLSDYFI 281

Query: 321 SSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFM 380
           +SSHNTYLTG Q    SSLEAYVR L  GCRCIELD WDGPD  P I HG TLT+KIRF 
Sbjct: 282 NSSHNTYLTGHQLKGLSSLEAYVRALLQGCRCIELDIWDGPD-EPIITHGRTLTSKIRFR 340

Query: 381 DVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440
           DV++ IKE+AF  SEYPLILS+E++C++ QQ +MA  F   FGD+L+     +    LPS
Sbjct: 341 DVVQIIKEYAFEVSEYPLILSLENHCNIQQQAQMAEIFLKDFGDMLVTQDFCRGNV-LPS 399

Query: 441 PH 442
           P+
Sbjct: 400 PN 401


>UniRef50_UPI0000E49F73 Cluster: PREDICTED: similar to KIAA1092
           protein; n=2; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to KIAA1092 protein -
           Strongylocentrotus purpuratus
          Length = 684

 Score =  188 bits (457), Expect = 1e-45
 Identities = 95/201 (47%), Positives = 119/201 (59%), Gaps = 1/201 (0%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           Y  +  F   L S +  I+D Q  +V QDMT+ LSHY+I++SHNTYLT DQ    SS+ A
Sbjct: 59  YLGIDGFTSYLLSSECDIFDHQQRRVCQDMTQSLSHYFIAASHNTYLTEDQLKGPSSVAA 118

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           YV  L+ GCR +ELD WDG +  P IYHGHTLT+KI F   +  I +HAF TSEYP+I+S
Sbjct: 119 YVSALQKGCRWVELDVWDGANDEPIIYHGHTLTSKILFKAAIEAINQHAFETSEYPVIVS 178

Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEE 461
           IE++CS  QQR MA     VFGD L    +D++ + LPSPHD            P+  E 
Sbjct: 179 IENHCSPEQQRTMAHYITSVFGDKLHTDRIDEDLSYLPSPHDLQGKILIKGKRLPDDHEG 238

Query: 462 SSFAVRQE-EGKDLDLRNSIK 481
               V  E EG D D    IK
Sbjct: 239 DEGEVTDEDEGSDTDRGKKIK 259



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 56/145 (38%), Positives = 84/145 (57%), Gaps = 10/145 (6%)

Query: 1060 NPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS------PFVEVEIIGADYDSGVK 1112
            NP D  ++  + V P  + +++I  +   K  RG+ S      P++ VEI G   D   +
Sbjct: 342  NPQDMWNVGCQIVSPQILHIKIISGQQFPKP-RGSGSKGEVIDPYISVEIFGIPADCKEE 400

Query: 1113 LVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172
              TKTV  NG NP++++  EF V  PELAL+RFVV D+D  G+  FIGQ T P  CL+ G
Sbjct: 401  R-TKTVPHNGYNPIFDESFEFSVNLPELALVRFVVLDDDFIGD-EFIGQYTIPFECLQPG 458

Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197
            YR + L +   E L+ ++L VH+++
Sbjct: 459  YRHITLLSNTGEPLKPASLFVHVAV 483



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 42/140 (30%), Positives = 63/140 (45%), Gaps = 1/140 (0%)

Query: 934  IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQL 993
            + +E+SDL+  C+SV F       +   Y E+ SF E  AE+  +     + V ++   L
Sbjct: 268  LIRELSDLVTLCKSVRFLGFNEARQDQRYWEICSFVENTAEKFANMCPEDY-VSHNKRYL 326

Query: 994  SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053
            SR+YP   R+DS+N NP   WN G Q+V+               K + +G  G ++ P  
Sbjct: 327  SRVYPNPNRVDSTNLNPQDMWNVGCQIVSPQILHIKIISGQQFPKPRGSGSKGEVIDPYI 386

Query: 1054 MFEEGYNPCDKKSIEGKVKP 1073
              E    P D K    K  P
Sbjct: 387  SVEIFGIPADCKEERTKTVP 406


>UniRef50_UPI00006CFB88 Cluster: Phosphatidylinositol-specific
           phospholipase C, X domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep:
           Phosphatidylinositol-specific phospholipase C, X domain
           containing protein - Tetrahymena thermophila SB210
          Length = 989

 Score =  188 bits (457), Expect = 1e-45
 Identities = 96/285 (33%), Positives = 172/285 (60%), Gaps = 17/285 (5%)

Query: 161 ENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDEN 220
           ++ ++++ L+EVK  L +++  ++   L+ +FQ  D  +  +I   +F  + +  I  ++
Sbjct: 155 KDGNKQLDLEEVKKLLQELHVSVNKKYLKQLFQTYDYNQNNQIDQGEFINIIRD-ISKKD 213

Query: 221 NVQDIFDKY------SVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDP 274
            +  IF +Y       V       +T+ E+Q FL+++Q  N+   E+   +  R+ + + 
Sbjct: 214 ELLTIFKQYCQSYNQQVSLDQEGLMTIEEYQLFLQEQQKQNVPIHELL--ELFRN-INNV 270

Query: 275 QRDIYEPYFTLSE-------FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTY 327
           Q ++ E   T  +       F  ++++++NS+ D ++ +V Q+M  PLS Y+I+SSHNTY
Sbjct: 271 QINVIESAKTSKDLKISFYQFSNLIFTQENSVLDIKHQEVHQNMNLPLSDYFINSSHNTY 330

Query: 328 LTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIK 387
           L  +Q + +SS +AY+     GCRC+ELDCWDG +  P +YHGHTLT++I F DVL+TI+
Sbjct: 331 LMANQLTGDSSCQAYINAFLRGCRCVELDCWDGENNEPLVYHGHTLTSRILFKDVLQTIE 390

Query: 388 EHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432
           ++AF+TS +P+ILS E++CS+ Q +++A   + +F D L   P D
Sbjct: 391 KYAFMTSPFPVILSFENHCSVEQSKKIAYYLKTIFKDKLFTVPKD 435



 Score =  134 bits (325), Expect = 1e-29
 Identities = 80/230 (34%), Positives = 123/230 (53%), Gaps = 10/230 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E K  +L+ +        +  + + R+YP G R+DSSNY+P+  +  G+Q+VALN
Sbjct: 740  ISSISEVKYLKLIKKCPGVLIQMFKKSFI-RLYPGGMRVDSSNYDPIKGFLSGAQIVALN 798

Query: 1025 YQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVML---R 1079
            +QTPD PM  N+ KF++NGG   G++LKP +M            +   VK V + +   +
Sbjct: 799  FQTPDLPMVFNLSKFQENGGIHSGYVLKPNYMLHHSKKDYIPTLMTKTVKVVRIQIISGQ 858

Query: 1080 VIGARHLCKTGRGTASPFVEVEIIGADYD--SGVKLVTKTVSDNGLNPLWND-ICEFEVA 1136
             +      +       P+V+V + G D+D  +    VT  V DNG +P+WN  + EF  A
Sbjct: 859  QLRPEDYEQDTFDVVDPYVQVFVKGTDFDENNNKPCVTDVVYDNGFHPIWNSHVFEFRFA 918

Query: 1137 NPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEEL 1186
             PELA+I F V D D+ G    +G     + C+R GYR +PL +  + EL
Sbjct: 919  CPELAMIVFRVMDSDV-GIDTQLGIYAISVDCMRPGYRMIPLRSKSNLEL 967


>UniRef50_Q4T850 Cluster: Chromosome 16 SCAF7896, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 16 SCAF7896, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1045

 Score =  185 bits (451), Expect = 6e-45
 Identities = 93/252 (36%), Positives = 152/252 (60%), Gaps = 8/252 (3%)

Query: 193 QDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDE 251
           ++ DT+ ++G + +++F+V Y+ +       +D+F     Y      +T  E  NFL +E
Sbjct: 2   EEADTDDQQGTLTYEEFSVFYKMMSLR----RDLFLLMMAYSDRKDHLTAEELANFLHNE 57

Query: 252 QHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDM 311
           Q       E  A    +  + D  +   +    +  F   + S    I++  +++V QDM
Sbjct: 58  QKMTNVTPEYVAEIIQKFEVADENKQ--KGVMGIEGFTNFMRSPACDIFNPLHNEVNQDM 115

Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGH 371
            +PL +Y+I+SSHNTYLTGDQ  S S  + Y   L+SGCRC+E+DCWDGPDG P + HG+
Sbjct: 116 EQPLCNYFIASSHNTYLTGDQLLSHSKTDMYAWVLQSGCRCVEVDCWDGPDGEPMVQHGY 175

Query: 372 TLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV-HP 430
           TLT+KI F  V+ TI ++AFI +++P+ILSIE++C++ QQ+++A   +++FGD L V   
Sbjct: 176 TLTSKIPFRFVIETINKYAFINNQFPVILSIENHCTIQQQKKIAQYLREIFGDKLDVGDV 235

Query: 431 MDKNETSLPSPH 442
           +  +  +LPSP+
Sbjct: 236 LSGDSKTLPSPN 247



 Score =  172 bits (418), Expect = 6e-41
 Identities = 106/278 (38%), Positives = 157/278 (56%), Gaps = 19/278 (6%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            +  +T ++++++S+L+++  SV    E L  +G    ++ SF ET+A+ L++ +   F  
Sbjct: 430  RKRKTMKLSRDLSNLVVFTNSVASQ-ECLN-EG-TPADVLSFSETRAQSLVNHRAEQFLA 486

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
             ++  QLSRIYP   RIDSSN+NP  +WN G Q+VALNYQT  + MQ+N  KF  NGG G
Sbjct: 487  -FNQRQLSRIYPSAYRIDSSNFNPQFYWNVGCQLVALNYQTEGRMMQLNRAKFMVNGGIG 545

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099
            ++LKP  M +  +NP     +    K   ++L++I  + L K        RG    PFVE
Sbjct: 546  YVLKPPPMCKGSFNPFSDDPLPACPKK-QLILKIISGQQLPKPPDSMLGDRGEIIDPFVE 604

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159
            VEIIG   D   K  T+ V DNG NP+W +   F +   E+ L+RF+V D D  G  +FI
Sbjct: 605  VEIIGLPVDC-CKEQTRVVDDNGFNPVWEETLSFTLHMAEVVLVRFLVWDHDPIGR-DFI 662

Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            GQ T     L  GYR V     + E L  +++ VH+S+
Sbjct: 663  GQRTVAFNSLMPGYRHV-----YLEGLTEASIFVHVSV 695


>UniRef50_UPI000069FB24 Cluster:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C)
            (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide
            phospholipase C-like 4) (Phospholipase C-like 4); n=1;
            Xenopus tropicalis|Rep:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C)
            (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide
            phospholipase C-like 4) (Phospholipase C-like 4) -
            Xenopus tropicalis
          Length = 574

 Score =  184 bits (449), Expect = 1e-44
 Identities = 104/256 (40%), Positives = 151/256 (58%), Gaps = 18/256 (7%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            + ++T ++++ +SDL+ Y +SV  +            ++SSF ETKA +++ QQ+   FV
Sbjct: 320  RQKKTMKLSRALSDLVKYTKSVGIHDVETESNW----QVSSFSETKAHQIL-QQKPAQFV 374

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +++  QLSRIYP   R+DSSNYNP PFWN G Q VALNYQ+  + +Q+N  KF  NG CG
Sbjct: 375  RFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQSVALNYQSEGRMLQLNRAKFNSNGNCG 434

Query: 1047 FILKPQFMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASP 1096
            ++LKP+ M +     +NP  +  + G++K   ++LR+I  + L K        RG    P
Sbjct: 435  YVLKPKCMCQVIVGAFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPKDSMLGDRGEIIDP 493

Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156
            FVEVE+IG   D   K  T+ V DNG NP+W +   F V  PE++LIRF+V D D  G  
Sbjct: 494  FVEVELIGLPVDC-FKEQTRVVDDNGFNPMWEETLVFTVHMPEISLIRFLVWDHDPIGR- 551

Query: 1157 NFIGQATFPLLCLRKG 1172
            +FIGQ T     +  G
Sbjct: 552  DFIGQRTLSFSSMMPG 567



 Score =  182 bits (442), Expect = 7e-44
 Identities = 90/243 (37%), Positives = 148/243 (60%), Gaps = 7/243 (2%)

Query: 200 RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDD 259
           +G +GFD+F   Y+ +    +  +D++     Y ++   +   + + FL  EQ   +   
Sbjct: 1   QGTLGFDEFCAFYKMM----STRRDLYLLMLTYSNHKDHLDPDDLKRFLEVEQK-MINVT 55

Query: 260 EVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYW 319
           +      +  +   P+    +    +  F   + S    I++  + +V QDMT PLS+Y+
Sbjct: 56  KEYCLDIVDKFEPCPENK-KQGALGIDGFTNYMRSPAGDIFNPDHYQVNQDMTLPLSNYF 114

Query: 320 ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRF 379
           I+SSHNTYL GDQ  S+S ++ Y   L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F
Sbjct: 115 IASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILF 174

Query: 380 MDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSL 438
            DV+ TI ++AFI ++YP+ILSIE++CS+ QQ++MA    ++ G+ L L   ++++ T L
Sbjct: 175 KDVIETINKYAFIRNDYPVILSIENHCSVVQQKKMAQYLIEILGEKLNLSDVVNEDSTKL 234

Query: 439 PSP 441
           PSP
Sbjct: 235 PSP 237


>UniRef50_UPI0000E817B6 Cluster: PREDICTED: hypothetical protein;
           n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 729

 Score =  183 bits (446), Expect = 2e-44
 Identities = 143/455 (31%), Positives = 215/455 (47%), Gaps = 31/455 (6%)

Query: 2   KSVCFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    DR I+ A   IS++  G  + K     R   R   +  +   V W     
Sbjct: 21  KTVSFSTMPNDRKINSAAACISFMLEGCELKKVRSNSRMYSRFFVLDADMRSVRWE---- 76

Query: 61  PQRQGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119
           P ++  E A ++I+ VKEVR GK +    R    + +      F+I YG  ++      V
Sbjct: 77  PSKKDSEKAKIEIKSVKEVRVGKKTPIL-RSNGLSDQFPDECAFSIIYGDNYE--SLDLV 133

Query: 120 AQTDKECEAWVKGVLYLIA------EAVSASYPLQIERWLRKEF--YSIENS-HEKIT-- 168
           A +     AWV G+ YL++      EA+ + +P     W+   F    +E S H  ++  
Sbjct: 134 ASSADVVSAWVMGLRYLLSYGKHTPEALGSGHPSLRTSWISSVFDLADLEKSGHIPVSRA 193

Query: 169 LKEVKAFLPKINCKISTSKLRDVFQDVDTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFD 227
           ++ +KA  P +  K+ST +L+       +E+ G E+  D F   Y +L        +IF 
Sbjct: 194 VQLIKALNPGM--KVSTIELKFKELQKASERPGTEVACDLFVEAYCELC----TRPEIFF 247

Query: 228 KYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLS 286
               + SN   + L++   FL  EQ    G  E +  + I  Y  +P ++  E  Y  + 
Sbjct: 248 LLVQFSSNKEYLGLKDLLTFLEVEQGME-GITEEKCLEIISKY--EPSKEGREKGYLAID 304

Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346
            F   L S   SI+D Q+ +V QDM +PLSHY+ISS+H+  L  D F   S +  YV  L
Sbjct: 305 GFTRYLLSSDCSIFDPQHRRVCQDMAQPLSHYYISSAHSACLLEDNFWGRSDISGYVSAL 364

Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
             GCR IEL  WDGP+G P +Y   +  + + F  V+  I +HAF  S YPLIL +   C
Sbjct: 365 GLGCRSIELVLWDGPEGEPVVYTSPSAASCVPFRSVVGLIDQHAFAASAYPLILCLVVRC 424

Query: 407 SLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           S  QQR  A   +   G+ L + P D   + LPSP
Sbjct: 425 SAAQQRLAAQCLRKTLGEKLYLEPPDPARSYLPSP 459


>UniRef50_A7SXK4 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 553

 Score =  182 bits (443), Expect = 5e-44
 Identities = 89/230 (38%), Positives = 137/230 (59%), Gaps = 6/230 (2%)

Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271
           + K I     V  +F   S   SNG  +T+ + ++F+  +Q  ++        + I+ + 
Sbjct: 1   FYKFISKRKEVDLLFRNVS---SNGAWVTVDDLEDFMTKDQRFDV--THKTCKELIKKF- 54

Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331
              QR   +    +  F+  + S+  S+++  ++K+ QDM +PLSHY+I+SSHNTYL G 
Sbjct: 55  EVSQRGKAQLQLGIDGFLSFINSQHASLFNPAHEKIYQDMNQPLSHYFIASSHNTYLLGH 114

Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAF 391
           Q    SS++AY   L  GCRC+ELDCWDG D  P +YHGHTLT+K+ F D+++ IKE AF
Sbjct: 115 QLKGSSSVQAYRDVLERGCRCVELDCWDGDDEEPIVYHGHTLTSKVLFKDIVQAIKESAF 174

Query: 392 ITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
             S YP+I+S+E++CS+  Q +MA   + + G LL   P+D    +LPSP
Sbjct: 175 KVSPYPVIVSLENHCSVQFQIKMAEHLKGILGSLLYTTPVDFTLDALPSP 224



 Score =  163 bits (397), Expect = 2e-38
 Identities = 99/274 (36%), Positives = 154/274 (56%), Gaps = 15/274 (5%)

Query: 934  IAKEISDLIIYCRSVTFN--IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            +A E+S LI Y  +  F   IE + +  F  ++  SF E++    + +  + F V+++  
Sbjct: 276  VADELSQLINYISNEKFKSFIESMEMGHF--SQTHSFVESEMLYFLDKSASEF-VEFNKH 332

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
            Q+SRIYP   R+DSSNY+P+  W  G Q+VALN+QT  + MQ++ GKF+QNG  G++LKP
Sbjct: 333  QISRIYPGNLRVDSSNYDPIKPWTVGCQIVALNHQTNSEEMQLHYGKFRQNGNTGYVLKP 392

Query: 1052 QFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG------RGTASPFVEVEII 1103
            +F+   E  ++P  +      ++P  + L VI A  L +        R    P+V+VE+ 
Sbjct: 393  KFLRDPELTFDPDPQDGKFPGIQPKRLQLTVISAFQLLEIEESWSLVRDEPDPYVQVEVH 452

Query: 1104 GADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQAT 1163
            G   D      T  ++D  LNP+WN+  +  V  PELA+++FVV DED +G  +F+GQ  
Sbjct: 453  GVPADKAT-FTTHGLTDTTLNPVWNEEFQTIVHVPELAMVQFVVYDED-YGFDDFLGQVV 510

Query: 1164 FPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             P   L +GYR + L +     L  +TL VH+ I
Sbjct: 511  IPFESLMEGYRQIQLLDMSGLPLPGTTLFVHVKI 544


>UniRef50_A2QRK1 Cluster: Catalytic activity:
           1-phosphatidyl-1D-myo-inositol 4; n=11;
           Eurotiomycetidae|Rep: Catalytic activity:
           1-phosphatidyl-1D-myo-inositol 4 - Aspergillus niger
          Length = 1156

 Score =  182 bits (442), Expect = 7e-44
 Identities = 138/457 (30%), Positives = 216/457 (47%), Gaps = 43/457 (9%)

Query: 17  ADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVK 76
           A ++ + I+RG    K   ++R + R   +  +  +V W   N P ++ Y     + D+K
Sbjct: 226 APKVDAMIQRGVIFTKITKKRRKQVRFF-LDLDAGKVYWDLSN-PTKRFY-----VDDIK 278

Query: 77  EVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFK----LRCASFVAQTDKECEAWVKG 132
           E+R G  ++++    + ++  ES     +    E      ++    +A +D   E W   
Sbjct: 279 EIRVGVDARNYREEHQVSQDFESRWITVVIADAERSKGRSVKTLHLIAPSDYTLELWTTT 338

Query: 133 VLYLIAEAVSASYPL----QIE-----RWLRK--EFYSIE---NSHEKITLKEVKAFLPK 178
           + ++    +     L    Q E      W R+    Y         E +  + V++    
Sbjct: 339 LEHISRYRIGLMAGLAGSGQSEAVLKAHWQREMTRLYPKGLKLGELESLDFEAVESVCRS 398

Query: 179 INCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238
           ++   S + LR  F   D   +G++ F +F+    +L  +  +V+ IF K  V  S G  
Sbjct: 399 LHINCSKNMLRAQFSKADNNNKGKLYFSEFSDFVARLK-ERKDVKAIF-KERVASSEG-- 454

Query: 239 ITLREFQNFLRDEQHDNLGDDEVQ-ASQFIR----DYLRDPQ-------RDIYEPYFTLS 286
            TL EF  FLRD Q++++  D     S F R       R P        R    P   L 
Sbjct: 455 FTLEEFLAFLRDVQNEDVESDRSYWVSIFDRLVRKSRPRAPSLPEHPDGRPTGVPRLGLD 514

Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346
            F   L S  N +Y S+  +   D  RPL+ Y+ISSSHNTYL G Q +  SS EAY+  L
Sbjct: 515 AFTSFLSSSWNGVYASRAPQSRFD--RPLNEYFISSSHNTYLLGRQVAGASSTEAYISAL 572

Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
             GCRC+E+DCWDG DG P + HG T+TT + F D +  I  +AFI++++PLILS+E +C
Sbjct: 573 SQGCRCVEIDCWDGADGRPIVSHGRTMTTSVLFADCITVINRYAFISTDFPLILSLEVHC 632

Query: 407 SLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           +  QQ  M    ++ F D L++ P+  N   LPSP D
Sbjct: 633 NPEQQLAMVRIMKETFKDQLVLEPLLTNTFVLPSPED 669



 Score =  104 bits (249), Expect = 2e-20
 Identities = 92/307 (29%), Positives = 141/307 (45%), Gaps = 41/307 (13%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQEN-TFF 985
            K  +  +I K +SDL +Y R   ++      +   YN + SF E   E +    +N   F
Sbjct: 772  KRRQKSKITKPLSDLGVYTRGYKWH-SFTSPESQRYNHVYSFAERSFESICRDADNKAVF 830

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ-NGG 1044
             K++   L+R+YP G R+ SSN++P+ FW  G QM ALN+QT D  MQ+N   +      
Sbjct: 831  EKHNRKYLTRVYPSGFRLRSSNFDPLKFWRRGVQMAALNWQTYDVGMQLNQAMYAAGTDR 890

Query: 1045 CGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEV 1100
             G++LKP+ +         +KS E K   V   + V+ A+ L +          +P+VEV
Sbjct: 891  TGYVLKPESLRTVTTGEDRRKSTERKC--VRFTIEVVSAQQLPRPRSLGPDDNINPYVEV 948

Query: 1101 EIIGADYDSGVKLV------------------------TKTVSDNGLNPLWNDICEF--E 1134
            EI  AD D G   V                        TK    NG +P++ND  +F  +
Sbjct: 949  EIFSAD-DRGQSFVFGEGGLNTSARSGVSGIGYPHRRRTKIEQSNGYSPIFNDCFKFALD 1007

Query: 1135 VANPELALIRFVV---QDEDIFGEPNFIGQATF--PLLCLRKGYRSVPLTNAFSEELELS 1189
               P+L  +R+ V    D    G  + +  ATF   L  L +GYR +PL +A  ++   S
Sbjct: 1008 TKYPDLVFVRWTVWSSLDGRSAGNNSSVQLATFTAKLTSLSQGYRYLPLYDAGGDQYLFS 1067

Query: 1190 TLMVHLS 1196
            TL   ++
Sbjct: 1068 TLFCKIT 1074


>UniRef50_Q02158 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase; n=2; Dictyostelium discoideum|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase - Dictyostelium discoideum (Slime
           mold)
          Length = 801

 Score =  182 bits (442), Expect = 7e-44
 Identities = 118/418 (28%), Positives = 209/418 (50%), Gaps = 30/418 (7%)

Query: 27  GSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKSSKD 86
           G T+LK   + +P+++ L      +Q++          G +  ++  ++ E+R G  +  
Sbjct: 61  GLTILKISSKGKPQKKKLIFDLARNQIVC---------GKKKKVNFSEIDEIRVGHKTNI 111

Query: 87  FERWPEETKRLES----SKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVS 142
           F ++       E      + F+I +    + +   FV     E    V  + +++ E+ S
Sbjct: 112 FNQFKSSKNLKEDIESIQQSFSILFSGNLR-KTMDFVCSDIPERRQIVSALYHVVQESKS 170

Query: 143 ASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGE 202
            +       ++++E+  +    + I    +K  L ++N   S + L ++ +  D+     
Sbjct: 171 VNNEYN---FVKREWDRV--GKDSIDFSTLKKILARLNFTTSDAVLHNLMKFSDSNSDYH 225

Query: 203 IGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ 262
           + F +F+ L  KL+     ++ +F KY+    NG  + ++   +F R EQ       EV 
Sbjct: 226 LDFSEFSNLL-KLLRSHPEMKPVFYKYNG--GNGEWVPIQGMIDFFRIEQ------SEVW 276

Query: 263 ASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISS 322
             +  RD ++    +  +   +   F E +  + N         V QD ++PLS+Y+I+S
Sbjct: 277 TVEQCRDLIKKYHHERLD-CISFENFEEFICGEANLAQYPHTSTVYQDTSKPLSYYFINS 335

Query: 323 SHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDV 382
           SHNTYL+G Q    S+ E Y   LR GC+C+ELD WDG DG P I+HG+TLT++I+F  V
Sbjct: 336 SHNTYLSGHQLKGLSTSEMYTNTLRQGCKCVELDVWDGNDGDPIIFHGNTLTSQIKFSHV 395

Query: 383 LRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440
             TIK   F TS YP+ILS+E +CS+PQQ  MA+  +++FG++L   P+ +    LP+
Sbjct: 396 CETIKARGFETSPYPVILSLEVHCSVPQQIMMANHMKEIFGEMLPT-PLPEGTKELPT 452



 Score =  151 bits (365), Expect = 1e-34
 Identities = 94/273 (34%), Positives = 144/273 (52%), Gaps = 13/273 (4%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +IA E  +LI Y  S  F       K     ++ S  E K ++L+ Q E    V+     
Sbjct: 534  KIAPEFEELI-YLVSHGFKSGNTT-KEIPSYKIHSLVEEKVKQLV-QSEPREVVEASQNH 590

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L R+YP+G R DSSN++P+P W+ G Q+ ALN QT  +PM +N G F  NGGCG++LKP 
Sbjct: 591  LLRVYPRGTRFDSSNFDPMPGWSIGCQLAALNQQTSSEPMWINDGMFSDNGGCGYVLKPP 650

Query: 1053 FMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGT----ASPFVEVEIIGA 1105
             +     E Y+P   + I+   K   +++ VI AR L K  + T      P+V + I+G 
Sbjct: 651  CLLPGECETYDPTSPERIKSS-KYSRLIVNVISARQLPKYTKSTKGEVIDPYVTLSIVGT 709

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
             +D  V+  TK + +NG NP W +  EF + N +L+++   V D+D  G  N IG     
Sbjct: 710  HFDQKVE-KTKVIDNNGFNPHWGEEFEFPLYNSQLSMLLIRVDDKDKVGH-NRIGHHCIR 767

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
            +  +R GYR + L N F+  + L+ L+   + +
Sbjct: 768  VENIRPGYRILKLKNNFNRTIPLANLLCKFTFV 800


>UniRef50_UPI0000DB73F3 Cluster: PREDICTED: similar to no receptor
           potential A CG3620-PD, isoform D; n=2; Apis
           mellifera|Rep: PREDICTED: similar to no receptor
           potential A CG3620-PD, isoform D - Apis mellifera
          Length = 1074

 Score =  180 bits (439), Expect = 2e-43
 Identities = 132/407 (32%), Positives = 206/407 (50%), Gaps = 33/407 (8%)

Query: 62  QRQGYEG-ALDIRDVKEVRTGKSSKDFERWPE-ETKRLES--SKCFTIYYGTEF-KLRCA 116
           Q +G +G  +++  V ++R G   KD + + +  TK  E    KC TI  G ++  +   
Sbjct: 53  QSEGRDGDVIELCQVSDIRAGGLPKDPKLYDKLVTKHGEQLEEKCLTICSGVDYTNINYQ 112

Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASY-PLQI--ERWLRKEFYSIENSHEKITLKEV- 172
             V       + W+ G+  +     + +  PL    + W+R       N   K+ +K V 
Sbjct: 113 HVVCPDSATAKIWLDGIRSITHNVKANNVCPLTCLKKHWMRLRMLIDPNG--KVPVKVVA 170

Query: 173 KAFLPKINCKISTSKLRDVFQDV---DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY 229
           + F      K+    L D+       D  +  +  FD F  LY K I   N+++++F   
Sbjct: 171 RTFASGKTEKLVYQCLADLGLSSGKNDVIEPEDFTFDAFYALYHK-ICPRNDIEELFQ-- 227

Query: 230 SVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYEPY 282
           S+      TI L +   FL ++Q D  L +      DE +A + I DY ++      +  
Sbjct: 228 SITQGKADTINLDQLVMFLNEKQRDPTLNEILYPLYDEKRALEIINDYEQNEMAR-NQKT 286

Query: 283 FTLSEFVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
            T   F+  L S +N+ ++  + D V  DM +PL+HY+I+SSHNTYL G QF  +SS+E 
Sbjct: 287 MTKDGFIRYLMSDENAPVFLDRLD-VYMDMDQPLAHYYINSSHNTYLCGRQFGGKSSVEM 345

Query: 342 YVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399
           Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV+  +++ AF+TSEYP+I
Sbjct: 346 YRQVLLAGCRCVELDCWDGKGEDEEPIITHGKAMCTDILFKDVIYAVRDTAFVTSEYPVI 405

Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPH 442
           LS E++CS  QQ ++A    ++ GDLLL  P+     +    LPSP+
Sbjct: 406 LSFENHCSKKQQYKLAKYCDEILGDLLLKEPLKDYPLEPGVPLPSPN 452



 Score =  159 bits (387), Expect = 3e-37
 Identities = 99/265 (37%), Positives = 144/265 (54%), Gaps = 13/265 (4%)

Query: 938  ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997
            +S ++ Y + + F    +  +  +++ MSSF ET     +  Q   F V Y+  Q+SRIY
Sbjct: 526  LSSMVNYAQPIKFPGFDVAEQKNIHHNMSSFAETAGLNYLKTQAIEF-VNYNKRQMSRIY 584

Query: 998  PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055
            PKG R DSSNY P  FWN G QMV+LN+QT D PMQ+N GKF+ NG  G++LKP FM   
Sbjct: 585  PKGTRADSSNYMPQVFWNAGCQMVSLNFQTADLPMQLNQGKFEYNGSSGYLLKPDFMRRA 644

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK-LV 1114
            +  ++P  +  ++G V      ++VI  + L     GT   +VEVE+ G   D+  K   
Sbjct: 645  DRSFDPFAESPVDG-VIATQCSVQVIAGQFLSDKKVGT---YVEVEMYGLPTDTIRKEFR 700

Query: 1115 TKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172
            T+ V  NGLNP++N+      +V  P+LA +RF V DE        +GQ   PL  L+ G
Sbjct: 701  TRVVPANGLNPVYNEEPFLFRKVVLPDLAALRFAVYDE---SNGKLLGQRIVPLDGLQSG 757

Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197
            YR + L    +  + L  L  ++ I
Sbjct: 758  YRHISLRTEANFPMSLPMLFCNIEI 782


>UniRef50_P78585 Cluster: Phosphoinositide-specific phospholipase C;
           n=2; Sclerotiniaceae|Rep: Phosphoinositide-specific
           phospholipase C - Botrytis cinerea (Noble rot fungus)
           (Botryotinia fuckeliana)
          Length = 994

 Score =  180 bits (438), Expect = 2e-43
 Identities = 105/283 (37%), Positives = 159/283 (56%), Gaps = 11/283 (3%)

Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224
           E +  + V+     ++   S+  LR+ FQ  D  K  ++ F +F   + KL+    +V +
Sbjct: 268 EALDFEGVEQLCKNLHINTSSRFLRERFQQADATKSKKLIFSEFQE-FVKLMKRRGDVSE 326

Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ-ASQFIRDYLRDPQRD--IYEP 281
           I+ + +    N   ITL EF +F+   Q +N+  D  +  S F +   R   RD  + E 
Sbjct: 327 IYRELA--SDNVKGITLEEFIDFVNVVQGENVEKDRAKWESIFAKFARRSRSRDQPLQEG 384

Query: 282 YFT-LSEFVEMLYSKQNSIYDSQYDKVTQDMT--RPLSHYWISSSHNTYLTGDQFSSESS 338
               +SE  E L +   S+++   + V +  T  RP+  Y+ISSSHNTYL G Q + ESS
Sbjct: 385 EAARMSE--EALATFFTSVHNVPLETVPETFTLDRPMHEYFISSSHNTYLMGRQVAGESS 442

Query: 339 LEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
           +EAY+  L  GCRC+E+DCWDG DG P + HGHT+T  I F DV+ TI ++AF+ S +PL
Sbjct: 443 VEAYISALIKGCRCVEIDCWDGKDGRPIVNHGHTMTRPIMFSDVMYTIAKYAFVKSHFPL 502

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
            +S+E +C+  QQ  MA   ++  GDLL+  P+D +   LPSP
Sbjct: 503 WISLEVHCNDAQQAAMAQIIKEACGDLLVTEPLDPSSQVLPSP 545



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 86/311 (27%), Positives = 139/311 (44%), Gaps = 45/311 (14%)

Query: 930  RTWRIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQ-ENTFFVK 987
            +T +I K + +L IY   V F   +    K   YN + SF E+  +R    Q +     +
Sbjct: 643  KTSKIVKVLGELGIYSAGVKFRGFDDPESKA--YNHIFSFMESTFDRNSKTQIDRRAMTR 700

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK-QNGGCG 1046
            ++   L R+YP G R+ S+N++P+ +W    QMVALN+QT D  MQ+N   F       G
Sbjct: 701  HNMRYLMRVYPNGWRVASTNFDPLKYWRRSVQMVALNWQTHDLGMQMNDAMFAGGTDQSG 760

Query: 1047 FILKPQFMFEEGYNP-----CDKKSIEGKVKPVTVMLRVIGARHLCK----TGRGTASPF 1097
            ++LKP  + E    P          ++ + K V   + +I A+ L +        +  P+
Sbjct: 761  YVLKPSELREIKMLPSVPEEAGADHVKRERKNVNFSIDIISAQQLMRPKGLPSNRSVDPY 820

Query: 1098 VEVEIIGADYDS----GV---------------------KLVTKTVSDNGLNPLWNDICE 1132
            +EVE+  AD  S    GV                     K  T  V +NG NP++N    
Sbjct: 821  IEVEVYHADDKSKETKGVIGEGGLDASAKDGSSGLGAPHKRRTHIVQENGFNPVFNKKFN 880

Query: 1133 FEVAN--PELALIRFVVQ---DEDIFGEPNF-IGQATFPLLCLRKGYRSVPLTNAFSEEL 1186
            F +    PEL  +R+ V+   D   + +    +   T  L  L++GYR++PL +   ++ 
Sbjct: 881  FALTTKFPELVFVRWTVRCSSDGHSYNDKTLPLATYTAKLSSLKQGYRTLPLYDTNGDQF 940

Query: 1187 ELSTLMVHLSI 1197
              STL   + I
Sbjct: 941  LFSTLFCRVKI 951


>UniRef50_Q15147 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-4; n=70; Coelomata|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-4 - Homo sapiens (Human)
          Length = 1175

 Score =  180 bits (437), Expect = 3e-43
 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115
           +G EG  L+   +  +R+G   KD       E   +    LE  +   +  GT+   +  
Sbjct: 53  EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111

Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171
              VA+  +  + WV+G+  +I    A  VS    L+ + W++  F +  N++ KI ++ 
Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168

Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225
           + + F      K+    L+++   + + K  EI      ++ F  L QK I    +++D+
Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225

Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278
           F K  +       +T+ +  +FL + Q D  L +      D  +A Q I  Y  +P  D+
Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281

Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337
            +     S+ F   L S +N+       ++ Q+M  PL+HY+ISSSHNTYLTG QF  +S
Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341

Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           S+E Y + L +GCRC+ELDCWD  G D  P I HG  + T I F DV++ IKE AF+TSE
Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401

Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443
           YP+ILS E++CS  QQ +M+   +D+FGDLLL      HP++    +LPSP+D
Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453



 Score =  166 bits (403), Expect = 4e-39
 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S +I Y + V F    +  +  ++  MSSF E+     +      F V Y+ 
Sbjct: 558  TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYPKG R+DSSNY P  FWN G QMV+LNYQTPD  MQ+N GKF+ NG CG++LK
Sbjct: 617  RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P FM   +  ++P  +  ++G V   T  ++VI  + L     GT   +VEV++ G   D
Sbjct: 677  PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732

Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   T+ V +NGLNP++N+      +V  P+LA++R  V D++       IGQ   P
Sbjct: 733  TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
            L  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 789  LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822


>UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate
           phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel
           protein similar to vertebrate phospholipase C, gamma 2 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 270

 Score =  179 bits (436), Expect = 4e-43
 Identities = 105/281 (37%), Positives = 154/281 (54%), Gaps = 23/281 (8%)

Query: 481 KNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELH 540
           K G L + DP+DK +  H  V+++NKLYY+E    +                I    ELH
Sbjct: 2   KEGELSIWDPIDKRFYKHDCVISDNKLYYSEEKWEEQSTQ------------IKDSSELH 49

Query: 541 FAECWFHGKLAGNRQEAEDLLRAHAHLGDG---TFLVRESVTFVGDYCLSFWRQGKVNHC 597
            +E WFHG+LA  R  AE LLR +    DG   TFLVRES TF+G+YC+S W +G++ H 
Sbjct: 50  LSEPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQHY 109

Query: 598 RIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVP----QPNKHE 653
           RI    E G   F+L    CF S+  LI +YR   +    F + LK  +P    +P  H 
Sbjct: 110 RIFCFPENGHKIFFLKSKECFPSMCALIDYYRQQSIDYDRFNLCLKNFLPRLNFEPLHHM 169

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G  WF+++ +R +AE+ L +   DGAFL+R    E+ +FA+S R+E +IKH ++ ++   
Sbjct: 170 G--WFYSNMSRAEAEDCLLRIPRDGAFLIR-KRNERDTFALSIRSEGDIKHYKIFRKSSK 226

Query: 714 YTIG-TVKFESLIELVSYYENHPLYKKVKLWYPISEETVRR 753
           Y +    +F SL ++VS + N     K KL YP++ + V R
Sbjct: 227 YVLADAYEFFSLEDMVSCFRNQQFAGKTKLRYPVTPQLVER 267


>UniRef50_Q27J08 Cluster: Phospholipase C; n=1; Aplysia
           californica|Rep: Phospholipase C - Aplysia californica
           (California sea hare)
          Length = 965

 Score =  178 bits (434), Expect = 6e-43
 Identities = 115/409 (28%), Positives = 208/409 (50%), Gaps = 29/409 (7%)

Query: 2   KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    ++ I  A   ++Y++ GS ++K     R   R   +  +  ++ W   + 
Sbjct: 86  KTVSFSSMPTEKKIATAQDCLAYMQTGSELIKVRSNSRQYHRFFSLSGDVQEIRWQPTS- 144

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKC-FTIYYGTEFKLRCASFV 119
             ++ ++  + +  +KEVR GK+++      +E   +   +C F+I +G EF+      +
Sbjct: 145 --KKPHKARIAVSSIKEVRQGKTTEALRS--KEIIGVYPDECAFSIIFGEEFE--AMDLI 198

Query: 120 AQTDKECEAWVKGVLYLI-AEAVSASYPLQI-------ERWLRKEFYSIENSHEKITLKE 171
           A T  E   W  G+  L+ A + S++    I       + WL + F S   +   +  + 
Sbjct: 199 ASTPDEANIWTTGLTCLLNANSRSSNSSSSIGDMQRMRDSWLLELFQSASPAEGTLEEER 258

Query: 172 VKAFLPKINCKISTSKLRDVFQDVDTE----KRGEIGFDDFAVLYQKLIFDENNVQDIFD 227
           V + + KIN  I+ S +    ++++ +    KRG +  ++F  L++++    +   +I+ 
Sbjct: 259 VVSLMRKINTTITPSVICQKLKELEIKRGDGKRGRLSSEEFISLFKEI----STRPEIYF 314

Query: 228 KYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD-IYEPYFTLS 286
               Y SN   ++  +   FL  EQ       + +  + I  +  +P  +   +    + 
Sbjct: 315 LLVRYASNADYMSTDDLLLFLEAEQGMQRVTKD-KCLEIINKF--EPSTEGRRKGQLGID 371

Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346
            F   L S++  ++D ++ +V QDM++PLSHY+I+SSHNTYL  DQ    SS++ Y+R L
Sbjct: 372 GFTSYLLSEECELFDQEHSRVCQDMSQPLSHYFIASSHNTYLLEDQLKGPSSVDGYIRAL 431

Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395
           + GCRC+ELD WDGP+  P IYHGHTLT+KI F   +  I ++AF  SE
Sbjct: 432 KKGCRCLELDVWDGPNEEPIIYHGHTLTSKISFRAAVEAINQYAFFASE 480



 Score =  174 bits (423), Expect = 1e-41
 Identities = 90/220 (40%), Positives = 132/220 (60%), Gaps = 10/220 (4%)

Query: 985  FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
            FV ++   LSRIYP G RIDSSNYNP   WNCG  MVALN+QT    M +  G F++NGG
Sbjct: 504  FVNHNKKFLSRIYPNGMRIDSSNYNPQDLWNCGCHMVALNFQTAGLMMDLYHGWFQKNGG 563

Query: 1045 CGFILKPQFMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTAS------PF 1097
            CG+ LKP  M EE  Y   + + +   + P  + +++I  ++  K  +G+A+      P+
Sbjct: 564  CGYTLKPAIMREEIAYFSANTRDVIPGISPQILHVKIISGQNFPKP-KGSAAKGDVTDPY 622

Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157
            V +E+ G   D   +  TKTV  NG NP++++  EF++  PELAL+RF + D+D  G+  
Sbjct: 623  VTIEVFGIPSDCAEER-TKTVPHNGYNPIFDESFEFQINLPELALVRFAILDDDYIGD-E 680

Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            FIGQ T P  C++ GYR + L +     +E  TL +H++I
Sbjct: 681  FIGQYTIPFECMQTGYRHIQLLSNTGSVMENCTLFIHVAI 720


>UniRef50_Q21754 Cluster: Phospholipase c protein 4; n=2;
           Caenorhabditis|Rep: Phospholipase c protein 4 -
           Caenorhabditis elegans
          Length = 751

 Score =  178 bits (433), Expect = 9e-43
 Identities = 109/379 (28%), Positives = 198/379 (52%), Gaps = 13/379 (3%)

Query: 72  IRDVKEVRTGKSSKDFERWPEETKRLE---SSKCFTIYYG-TEFKLRCASFVAQTDKECE 127
           + ++ EVR+G  + + +R  ++ +  E    S+CF++ +   +F  +   F A + +  +
Sbjct: 76  LSELLEVRSGYQTDNLQRASKKYEFQELAPESRCFSVIFSHAKFLHKSVDFSADSKETRD 135

Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTS 186
            WV  + +LI+ A           WL  +F   + N +  ++  EV   L ++N +IS  
Sbjct: 136 KWVSVLTHLISVAKHQRVVFNETAWLIDKFQQADTNKNGLLSFDEVWNLLKRMNLQISER 195

Query: 187 KLRDVFQDVDTE--KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREF 244
             + +F++ + E  +  ++   +F   +++L  D  +++ +  + S    N  T+T+ + 
Sbjct: 196 YAKAIFRESEFENSRDNKLNEKEFLNFFERLT-DRPDLRFVMTQAS--SDNVETLTVADL 252

Query: 245 QNFLRDEQ-HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303
           Q FL +EQ  +N+  D  +A Q +  + +  Q    E    L     ++ S+  +++   
Sbjct: 253 QRFLTEEQGFENV--DLKKAEQILTTFEQTVQDKQKEKLMGLMGMRRLMQSRWGNVFKPG 310

Query: 304 YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG 363
           ++ + QDM +PL+HY+++SSHNTYLTG Q   E+++E Y+  LR G R +ELD +DG  G
Sbjct: 311 HESIFQDMDQPLTHYFVNSSHNTYLTGLQVKGEATVEGYISALRKGARLLELDLFDGEHG 370

Query: 364 TPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFG 423
            P I H  T    I   + L  IK  AF TS YP+IL++E++    QQ  MA  F+++ G
Sbjct: 371 EPVITHKRTFIESITLRNSLEAIKRTAFETSPYPVILTLENHVGFVQQAVMADLFKEILG 430

Query: 424 DLLLVHPMDKNETSLPSPH 442
           D L + P D +   L SP+
Sbjct: 431 DSLYIPPKDSHRHPLSSPN 449



 Score =  142 bits (345), Expect = 4e-32
 Identities = 82/260 (31%), Positives = 139/260 (53%), Gaps = 16/260 (6%)

Query: 947  SVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF------VKYHTTQLSRIYPKG 1000
            S    +  +++   +Y +++  P   +  L   +  T F        Y   +L + YPKG
Sbjct: 495  SALIGLPSVKLSHNIYQDVNKHPFDGSPSLSENKVYTMFEAAVPIFTYTAERLVKSYPKG 554

Query: 1001 QRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYN 1060
             R DSSN +P+  W CG Q VA+N+QT  + + +N G F+ NG CG++LKP  +  +G +
Sbjct: 555  LRQDSSNMHPMVSWLCGIQSVAMNFQTAGEELDLNAGLFRINGNCGYVLKPSCLL-DGVD 613

Query: 1061 PCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEVEIIGADYDSGVKLVTKTV 1118
            P  +   + K+K   + + +  A++L K+  G+    P+V V+I G   D   K  T+ +
Sbjct: 614  P--RSMAKPKLK---LGIGLFSAQYLPKSEPGKEIIDPYVSVQIFGIPRDE-TKAKTRII 667

Query: 1119 SDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
             DNG NP W D   F ++ PELA+IRF V+D D     +F+G+ + P++ LR G+  + L
Sbjct: 668  KDNGFNPEWRDNFYFTLSCPELAIIRFCVKDFDSTSSNDFVGEFSIPVMSLRTGFSQIQL 727

Query: 1179 TNAFSEELELS-TLMVHLSI 1197
               +   L+ S +L V +++
Sbjct: 728  NTGYQHTLDPSASLFVRIAM 747


>UniRef50_UPI00006CB024 Cluster: Phosphatidylinositol-specific
           phospholipase C, X domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep:
           Phosphatidylinositol-specific phospholipase C, X domain
           containing protein - Tetrahymena thermophila SB210
          Length = 850

 Score =  176 bits (429), Expect = 3e-42
 Identities = 92/283 (32%), Positives = 163/283 (57%), Gaps = 16/283 (5%)

Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224
           + +T +E    + K+N  IS   L + FQ  D      +  ++F  + + L+  ++ +  
Sbjct: 157 DNLTYEECLNLIQKLNVNISKKDLLEKFQFYDENNDKLLQVNEFVEIIRDLL-SKSELMP 215

Query: 225 IFDKYSVYCS-----NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIY 279
           +F KY    +     N   +    F  F++ EQ     + ++++ QF+  Y  +    I 
Sbjct: 216 LFKKYVPSFNEKSNLNSPAMKKETFFKFMKAEQKQE--EIDLKSQQFLDMYFAEKNNII- 272

Query: 280 EPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSL 339
               + ++F+ ++++ QN+IYD     V QDM +PL+ Y+I+SSHNTYL  +Q + ES++
Sbjct: 273 ----SYNDFINLIFNYQNNIYDPAKLSVYQDMDQPLTDYFINSSHNTYLMANQLTGESNV 328

Query: 340 EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399
           +AY+   R GCRCIE+D WDG +  P + HG TLT+ I+F DV++TIK + F+ S+YP+I
Sbjct: 329 QAYINAFRKGCRCIEIDVWDGSE--PIVTHGFTLTSSIKFRDVVQTIKTYGFVWSKYPII 386

Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSL-PSP 441
           +SIE++C+   Q++MA+  +++FG  + + P + +     PSP
Sbjct: 387 ISIENHCNQENQKKMANIMKEIFGSSIYLIPENYSSMKFYPSP 429



 Score =  128 bits (309), Expect = 9e-28
 Identities = 87/276 (31%), Positives = 147/276 (53%), Gaps = 27/276 (9%)

Query: 948  VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSN 1007
            V+F ++ ++ +     ++ S  E K + L+ + E    V YH    SRIYPKG R+DSSN
Sbjct: 573  VSFTMDMIKFQNGSIFDIFSLSEEKIKYLLKKHEK-IIVDYHKKFFSRIYPKGSRVDSSN 631

Query: 1008 YNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM--------FEE 1057
            ++P+P +  GSQ++ALN+QT D  M + + KF+QNGG   G++LKP+++          +
Sbjct: 632  FDPLPSFISGSQIIALNFQTCDYHMLMYLSKFQQNGGIFSGYVLKPKYLRHSHIQQINSD 691

Query: 1058 GYNPCD---------KKSIEGKVKPV-TVMLRVIGARHLCKTGRGTAS--PFVEVEIIGA 1105
             +  CD         +K     VK +  + + +I  + L +    + S  PF+EV + G 
Sbjct: 692  DHKLCDDLNKNKNTLQKYPSDFVKQIKEIKITIISGQCLKREEDDSKSFNPFIEVSLKGT 751

Query: 1106 DYD--SGVKLVTKTVSDNGLNPLWNDI-CEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
            + D  +     TK++++N  +P++N     F+VA PELA+I F V    I     F  Q 
Sbjct: 752  ELDEKNNKTQRTKSINNNTFHPIFNSSPITFKVACPELAMISFQVFSNGIIKNELF-AQY 810

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
                 C+R+GYR +PL +   +++E   L+ H+ I+
Sbjct: 811  ALDFECIREGYRIIPLWDKEFKKIEHGMLLAHIEIL 846


>UniRef50_A2TJ25 Cluster: Phospholipase C beta 3; n=8;
            Clupeocephala|Rep: Phospholipase C beta 3 - Danio rerio
            (Zebrafish) (Brachydanio rerio)
          Length = 1244

 Score =  175 bits (427), Expect = 5e-42
 Identities = 105/266 (39%), Positives = 152/266 (57%), Gaps = 13/266 (4%)

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
            +E+S L+ Y   V F    +  K   + EMSSF ETK    +     T FV+Y+  Q+SR
Sbjct: 568  EEMSTLVNYIEPVKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSP-TEFVEYNKKQMSR 626

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM- 1054
            IYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG F+ NG CG++LKP+FM 
Sbjct: 627  IYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMR 686

Query: 1055 -FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKL 1113
              ++ ++P     ++G V   TV +++I  + L     G    +VEV++ G   D+  K 
Sbjct: 687  RTDKHFDPFTTDIVDGIVAN-TVKVKIISGQFLNDKKVGV---YVEVDMFGLPADTKRKY 742

Query: 1114 VTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
             TKT ++N L+P+W+D      +V  P LA +R  V +E+      FIG    P+  LR 
Sbjct: 743  RTKTSNNNSLDPVWDDETFVFNKVVLPTLASLRVAVYEEN----GKFIGHRILPVSALRP 798

Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197
            GY  + L N  ++ L L +L+V+  +
Sbjct: 799  GYHYICLKNELNQPLMLPSLLVYTEV 824



 Score =  168 bits (409), Expect = 7e-40
 Identities = 127/430 (29%), Positives = 205/430 (47%), Gaps = 32/430 (7%)

Query: 70  LDIRDVKEVRTGKSSKD--FERWPE-----ETKRLESSKCFTIYYGTEF-KLRCASFVAQ 121
           LD+  +++ RTGK +K    +R  E     +      S+  T+ YG +   +   +F A 
Sbjct: 66  LDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAV 125

Query: 122 TDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KAFLP 177
            D  C+ W   +  L    +S +       +L K +  ++       KI +K + K F  
Sbjct: 126 QDGYCKLWTDELFKLATNMLSQN--ASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD 183

Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237
           K   +++      +F  VD  K  +  ++ F     KL      V+ IF    +      
Sbjct: 184 KKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLS-PRPEVERIF--VDLGSKGKP 240

Query: 238 TITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
            ++L +  +F+  +Q D+  ++ +       Q  Q +  Y  +  + +     +L  F +
Sbjct: 241 FLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQ-LERDQISLMSFTK 299

Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350
            L  ++N++   +   +  DM +PLSHY+I+SSHNTYLT  Q +  SS+E Y + L +GC
Sbjct: 300 YLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGC 359

Query: 351 RCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-S 407
           RCIELDCW G  P+  P I HG T+TT+I F DV+  I E AF TS YPLILS E++  S
Sbjct: 360 RCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDS 419

Query: 408 LPQQRRMASAFQDVFGDLLLVHPMDKNE----TSLPSPHDXXXXXXXXXXXXPEGAEESS 463
             QQ +MA   + +FGD LL+ P+DK        LPSP +                  + 
Sbjct: 420 AKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNG 479

Query: 464 FAVRQEEGKD 473
            ++R+++G D
Sbjct: 480 GSIRRKDGTD 489


>UniRef50_Q5MG88 Cluster: Phospholipase C delta 1; n=2; Toxoplasma
           gondii|Rep: Phospholipase C delta 1 - Toxoplasma gondii
          Length = 1097

 Score =  174 bits (424), Expect = 1e-41
 Identities = 119/422 (28%), Positives = 210/422 (49%), Gaps = 29/422 (6%)

Query: 19  QLISYIERGSTVLKFFPR--KRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVK 76
           + +  +  GS +LK+     K+P  R   V      + W    +P++      + + DV+
Sbjct: 128 EALQTLAEGSFLLKWCKTNFKKPHERFFYVDANAMALKW---RSPKKPESVTTIPVGDVQ 184

Query: 77  EVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYL 136
            +  G+ + DF R     K  +S     +  G    + C     + +KE   W+KG+L  
Sbjct: 185 RIIPGEDT-DFGR----NKADKSHSIEIVATGRVLHVAC-----RDEKEWRLWMKGLLLY 234

Query: 137 IAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDV 195
              A+          ++  +++++E   + KI  + +   L K+N +     + ++FQ  
Sbjct: 235 HDMALGQLASEGASDFVSAQWHAVEKDADGKIDQRHLHGLLRKLNIQADGRYVEELFQTH 294

Query: 196 DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQH-D 254
           DTE  G +GF +F  +  +L+    +V   F  Y +   +   I  + ++ FLR+ Q   
Sbjct: 295 DTENSGRLGFTEFREMLNELLV-RPDVDYYFTVYKL--PHEDFIDEQGYRRFLREVQKVT 351

Query: 255 NLGDDEVQASQF--IRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312
           +  + E + + F  + +  R P   +     +   F  +L  + NS+      KV QDM+
Sbjct: 352 SEAEVEEELASFCSVDEAFRKPGPTVM---VSSLGFDNLLCGEANSLMAPHRMKVHQDMS 408

Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH--- 369
            PL +YW+ SSHNTYL GDQ   +S++  Y+  L  GCRC+ELDCWDG DG P ++H   
Sbjct: 409 LPLCNYWVKSSHNTYLCGDQVVGKSAVGQYIDALLRGCRCVELDCWDGSDGEPSLFHGVG 468

Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD-LLLV 428
           G+ LT++I+F DV++  K++ F  S++P+ILS+E +CS  Q+ R+A   +++  D +   
Sbjct: 469 GYQLTSRIKFKDVIQACKDYGFQRSKFPIILSLEMHCSTKQRIRIAEILEEILQDQIYRC 528

Query: 429 HP 430
           HP
Sbjct: 529 HP 530



 Score =  107 bits (257), Expect = 2e-21
 Identities = 89/282 (31%), Positives = 133/282 (47%), Gaps = 30/282 (10%)

Query: 944  YCRSVTFNIERLRIKGFVYNEMS--SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQ 1001
            Y R++    ++LR      N M   S PE++  +L+ Q     F  ++   L+R+YP G 
Sbjct: 789  YYRNIAMPGKKLRSFEQARNPMDICSMPESRLLKLVKQSP-VEFASFNQRFLTRVYPAGT 847

Query: 1002 RIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEG- 1058
            R+ SSN++PV  W  G+Q+VALN Q+      +N G+F  NGG   G++LKP+ M     
Sbjct: 848  RLQSSNFSPVVPWLFGAQVVALNLQSLGSATILNEGRFLDNGGPAGGYVLKPEMMRNPAR 907

Query: 1059 -YNPCDKKSIEGKVKPVTVMLRVIGARHL----------------CKTGRGT--ASPFVE 1099
             + P   +    +  PV   ++++ A  L                 KT + T  + PFV 
Sbjct: 908  PFVPAFAELSACRETPVHFTIKILSAHQLPRPVTDPWKGPSTINKIKTRKSTDLSCPFVS 967

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWN---DICEFEVANPELALIRFVVQDEDIFGEP 1156
            V I G   D+     T TV +NG NP W+      EF V  P +AL+ F VQ  D     
Sbjct: 968  VSIHGVKEDTKA-FRTSTVMNNGFNPRWSSPESTFEFIVHAPSVALLVFKVQTADSV-RS 1025

Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
             F+  A FP   +R G R VPL +     L  + L+V+  I+
Sbjct: 1026 EFLAAACFPFDAIRPGIRWVPLFDRKFCRLRWTGLLVYSRIV 1067


>UniRef50_Q9TZN8 Cluster: Phosphoinositide-specific phospholipase C;
           n=5; Trypanosoma|Rep: Phosphoinositide-specific
           phospholipase C - Trypanosoma cruzi
          Length = 725

 Score =  174 bits (423), Expect = 1e-41
 Identities = 99/210 (47%), Positives = 130/210 (61%), Gaps = 11/210 (5%)

Query: 238 TITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQN 297
           TIT  EF++FLR+ Q + L  + V+    I DY+   +    E YFT   F++ L   + 
Sbjct: 180 TITRDEFKSFLRNYQGEELNGERVKE---ILDYVCCMKTG--EVYFT--NFLKFLEDNRF 232

Query: 298 -SIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355
            SI D +   KV QDM +P+ +Y+I+SSHNTYLTGDQ +S SS + Y + L  GCRC+EL
Sbjct: 233 CSIVDEEKVSKVYQDMNQPICNYFINSSHNTYLTGDQLTSNSSADMYRKALLDGCRCVEL 292

Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415
           DCWDG  G P +YHGHT T+KI F+  ++ IKE+AF  SEYP+ILSIE + S  Q  RMA
Sbjct: 293 DCWDGFAGEPIVYHGHTRTSKISFLSCIKVIKEYAFKASEYPVILSIEVHTSSAQADRMA 352

Query: 416 SAFQDVFGDLLLVHPMDKNE--TSLPSPHD 443
               D FGD+L   P    E  T L SP +
Sbjct: 353 EIMCDTFGDMLFQSPWAPAEPTTFLFSPEN 382



 Score =  110 bits (264), Expect = 3e-22
 Identities = 78/226 (34%), Positives = 115/226 (50%), Gaps = 21/226 (9%)

Query: 964  EMSSFPETKAERLMSQQENTF-FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVA 1022
            + +SF E+KA+++       F  +  H   LSRIYP G R+ SSNYNP  FWNCG Q+VA
Sbjct: 490  QCTSFVESKAKKIAVSNAMEFKLINQHC--LSRIYPAGSRVGSSNYNPQLFWNCGCQIVA 547

Query: 1023 LNYQ-TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI 1081
            LN+Q T     ++N G F  NG CG++LKP+ +           S  G  +  ++ L +I
Sbjct: 548  LNWQSTHTYAWRLNKGFFSDNGNCGYVLKPESVRSSA------ASRNGS-QVRSLNLEII 600

Query: 1082 GARHLCKTGRGT----ASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI---CEF- 1133
                L K  R        PF+   I G D +S  K  + T+ +NG +P+W       EF 
Sbjct: 601  SGFCLPKPKRSNKGEIVDPFITCFIEGPDGNSDRK-TSGTIRNNGFHPVWRGKGLGTEFS 659

Query: 1134 -EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
             +V + +L+ +   V DED     +F+ +   PL  L+ G R +PL
Sbjct: 660  WDVKDWDLSTLVVQVYDEDKKTRDDFLAECILPLRVLKAGIRQIPL 705


>UniRef50_Q8IA75 Cluster: Phospholipase c like protein 1, isoform a;
            n=3; Caenorhabditis|Rep: Phospholipase c like protein 1,
            isoform a - Caenorhabditis elegans
          Length = 1075

 Score =  173 bits (420), Expect = 3e-41
 Identities = 104/275 (37%), Positives = 154/275 (56%), Gaps = 17/275 (6%)

Query: 933  RIAKEISDLI-IYCRSVTFNIERLRIKGFVY----NEMSSFPETKAERLMSQQENTFFVK 987
            ++ KE+SDL+ ++    T N       G         ++S  E+   RLM     T F +
Sbjct: 547  QLCKELSDLVPVFFNVKTLNDLLSTAPGSTTMSSRKNLASVTESTCLRLMHTYA-TEFGQ 605

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047
                   R++P   R+DSSN NP  FWN G QMV LNYQTP   M +  GKF  NGGCG+
Sbjct: 606  ATRNYCVRVFPNPSRVDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGY 665

Query: 1048 ILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRG-TASPFVEVEI 1102
            +LKPQ M ++ + P D+        P  + LR++  + L +      +G +A PFV VE+
Sbjct: 666  VLKPQVMKDDMFVPSDRV----PTSPQILHLRILSGQQLPRPRGSNAKGDSADPFVVVEV 721

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
             G   D   +  T+TV ++ +NP +++  +F+V+ PELAL+RF+V D+D  G+ +FIGQ 
Sbjct: 722  FGLPGDCAEER-TRTVRNDSINPSFDESFQFQVSVPELALVRFLVLDDDYIGD-DFIGQY 779

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            T P  CL+ GYR + L N   + LE +TL VH++I
Sbjct: 780  TIPFECLQPGYRHIYLLNNEGDPLEHATLFVHVAI 814



 Score =  149 bits (361), Expect = 5e-34
 Identities = 122/462 (26%), Positives = 206/462 (44%), Gaps = 34/462 (7%)

Query: 2   KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    D  I       +Y++ GS  +K     R  RR   +  +   + W+  N 
Sbjct: 59  KTVSFSSKNSDAKISNVSDCWNYMQTGSDFVKLRGTNRQFRRFFSLDADLSYIRWTPTN- 117

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
             ++ ++  + I +++E+R GK+++      E    L+    F+I YG  ++      +A
Sbjct: 118 --KKPHKARIAIDEIREIRLGKNTELLRSSDEVFTDLQEECLFSIIYGDNYET--LDLIA 173

Query: 121 QTDKECEAWVKGVLYLIAEAV-----SASYPLQIERWLRK---EFYSIENSH--EKITLK 170
            +  +   WV G++ L +        S+ +    ERW+     EF + +N H  E+   K
Sbjct: 174 SSGDDANIWVTGLMALTSNKYECKPSSSQFATLRERWIESVFDEFDTKKNGHLDEQTAFK 233

Query: 171 EVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYS 230
            +     +I+    T+KL++V    +  +RG+I    F  LY++ I     V  +  +Y+
Sbjct: 234 AILHINSRISHHRLTNKLKEVTIGAEESERGKIEKSHFVDLYKE-IGTRPEVYFLMVRYA 292

Query: 231 VYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFV 289
               N   ++ ++ + FL  EQ   +G         I  Y  +P  +  E    T+  F 
Sbjct: 293 ----NKDYLSCQDLRLFLETEQ-GMVGVTTDNCETLIEQY--EPCSEARENNLMTVDGFT 345

Query: 290 EMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349
             L+S    ++D  +  VT DM +P S Y+ISSS  +YL  DQ    SS + +   L+  
Sbjct: 346 SFLFSPDCGVFDPNHRVVTMDMKQPFSRYFISSSRKSYLVEDQLGPSSS-DGFSSALKRN 404

Query: 350 CRCIELDCWD----GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           CR +E D WD      D  P + +G T T+KI     LR I+E AF  S YPL+L +  +
Sbjct: 405 CRFLEFDIWDPNEADGDTEPMVQNGQTATSKITISSALRIIREFAFERSRYPLLLKVSVH 464

Query: 406 CSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443
           CS   Q+  A       G  L +   D     +E + P+P D
Sbjct: 465 CSTDWQKVAAMLIVTHLGTRLYLPKNDPTNWDDEKNCPTPWD 506


>UniRef50_O97036 Cluster: PLC-betaH2; n=2; Eukaryota|Rep: PLC-betaH2
           - Hydra magnipapillata (Hydra)
          Length = 1364

 Score =  172 bits (419), Expect = 4e-41
 Identities = 125/394 (31%), Positives = 209/394 (53%), Gaps = 34/394 (8%)

Query: 71  DIRDVKEVRTGKS-SKDFERWPEETKR-LESSKCFT-IYYGTEF-KLRCASFVAQTDKEC 126
           DI  VK+  T K+ +K FE++ +E K  ++    FT I +GT   ++   +F   T +  
Sbjct: 65  DISYVKDGATPKALNKVFEQYSDEEKNNVDFLSRFTYICFGTNIVEVSFITFDFMTKELK 124

Query: 127 EAWVKGVLYLIAEAVSASYPLQIERWLRKEFY---SIENSHEKITLKEVKAFLPKINCKI 183
           + +   +   +     A     +++ L K++    S+ N+  KI++K +   L  +  + 
Sbjct: 125 QIFFSCISTNLTNHKHAFRNPSVKQMLYKQYVLSKSMVNASGKISMKNIFKCLNAVRFEQ 184

Query: 184 ST-----SKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238
           +T     + L     ++D E      F+ F  L   L+    ++ ++F   S++   GT 
Sbjct: 185 TTIEGIQTALSLPVGEIDPEM---FSFEQFYKLCC-LVCPRPDIDELF--ISLF---GTR 235

Query: 239 ITLREFQNFLRDEQHDNLGDDEVQ-------ASQFIRDYLRDPQRDIYEPYFTLSEFVEM 291
           +T  +   FL ++Q D   ++++        A   I DY  +      E   T+  F+++
Sbjct: 236 LTAEKLMKFLNEDQRDPRLNEQMHPHCTISNAVDLIMDYESNEACRTKE-LLTIQGFIQL 294

Query: 292 LYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCR 351
           L SK++++ + +   +  DM +P++HY+I+SSHNTYL G Q   +SS+E Y + L SGCR
Sbjct: 295 LLSKESAVLNPECLLLRHDMNQPINHYFINSSHNTYLLGRQVYGKSSVEIYRQVLISGCR 354

Query: 352 CIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQ 411
           CIELDCWDGP G P I HG  + T + F DV++ I + AF+TS YP++LS E++CSLPQQ
Sbjct: 355 CIELDCWDGP-GVPIITHGKAMCTNVLFSDVVQAIADTAFLTSPYPVVLSFENHCSLPQQ 413

Query: 412 RRMASAFQDVFGDLLLVHPMDKNE----TSLPSP 441
           + +A     +FG LLL  P++ N       LPSP
Sbjct: 414 KILAEMCIKIFGPLLLDKPLESNPLEPGIELPSP 447



 Score =  138 bits (333), Expect = 1e-30
 Identities = 91/248 (36%), Positives = 131/248 (52%), Gaps = 22/248 (8%)

Query: 958  KGFVYNE-------MSSFPETKAERLMSQQEN-TFFVKYHTTQLSRIYPKGQRIDSSNYN 1009
            KGF Y E       MSSF E   E L    EN T FV Y+  Q SRIYPK  R++S+NY 
Sbjct: 704  KGFEYAEEQKKHYIMSSFSEL--EGLKQCTENLTDFVLYNKRQFSRIYPKATRVESTNYV 761

Query: 1010 PVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFE--EGYNPCDKKSI 1067
            P  FWN G Q VALN QTPD  +Q+N  KF+ N  CG++LKP    E    ++P  +  I
Sbjct: 762  PQVFWNAGCQFVALNLQTPDLSVQLNQQKFECNFNCGYLLKPVKYRETDSNFDPLTENPI 821

Query: 1068 EGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW 1127
            +G + P+TV + VI  ++L +        +V++++ G   D+  K  T     N +N ++
Sbjct: 822  DG-IIPLTVEIEVISGQYLSEK---KCMTYVQIDMFGLSADTTRKKRTNLSESNLMNTVY 877

Query: 1128 -NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185
               + +F+ +  PE+ L+RF V DE        +GQ   PL  ++ GYR + +       
Sbjct: 878  PKTVFKFDKIVFPEMVLVRFTVYDE----SDKLLGQRVLPLEGIKSGYRHIAMRTETGHF 933

Query: 1186 LELSTLMV 1193
            L L+TL V
Sbjct: 934  LPLTTLFV 941


>UniRef50_Q9NBA8 Cluster: Phospholipase C; n=3; Decapodiformes|Rep:
           Phospholipase C - Loligo pealeii (Longfin squid)
          Length = 1127

 Score =  171 bits (416), Expect = 1e-40
 Identities = 115/362 (31%), Positives = 182/362 (50%), Gaps = 23/362 (6%)

Query: 101 KCFTIYYGTEF-KLRCASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFY- 158
           KC TI +G  +  L     VA+       W + V       +S +   Q+  W +  F  
Sbjct: 104 KCVTICHGYNYIDLDWIHLVAENSSVAAKWAEEVFSYAYNLLSLNKN-QLGEWEKLYFRL 162

Query: 159 -SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV-------DTEKRGEIGFDDFAV 210
            ++E    KI +K ++  L K   K   +++    + +       D  +     FD F  
Sbjct: 163 TTVEMEKNKIPVKSIQKCLSKD--KDDRTRVAKAIEKIGWPSGKNDAIEIKAFDFDTFFK 220

Query: 211 LYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ--HDNLGD--DEVQASQF 266
            Y  L+ + + ++ IF + S    N TT+  R+F N ++     H  L     + Q    
Sbjct: 221 FYLSLL-ERSEIEGIFKELSQNKGNITTVMFRDFLNDMQRHPSLHKTLFPLYTDSQCDAL 279

Query: 267 IRDYLRDP-QRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHN 325
           I +Y     ++   +   T    +  L  ++N++       +  +M   L+ Y+I+SSHN
Sbjct: 280 INEYESAVNKKGKKKGQLTKEGLLYFLMCEENNLTPMHRLDLGANMKLSLAAYYINSSHN 339

Query: 326 TYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRT 385
           TYLTG Q + +SS+E Y + L +GCRC+ELDCWDG DG P I HG T+ T+++F DV+  
Sbjct: 340 TYLTGHQLTGKSSVEIYRQVLLTGCRCLELDCWDGKDGEPIITHGFTMCTEVQFKDVVHA 399

Query: 386 IKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSP 441
           I E AF  SEYP+ILS E++CS+PQQ+ +A    + FG+LLL +P+D    K    LP+P
Sbjct: 400 IAECAFKVSEYPVILSFENHCSVPQQKLLAQYCHEAFGELLLDNPIDGHPLKPGVPLPTP 459

Query: 442 HD 443
           +D
Sbjct: 460 YD 461



 Score =  165 bits (402), Expect = 5e-39
 Identities = 101/267 (37%), Positives = 157/267 (58%), Gaps = 16/267 (5%)

Query: 935  AKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKA-ERLMSQQENTFFVKYHTTQL 993
            A+E+S L+ Y + V F       K   + EMSS  ET+A  +L    E+  FV Y+  QL
Sbjct: 511  AEEMSALVNYIQPVHFTTFEQAQKKDRHYEMSSMVETQALNKLKDNPED--FVDYNKKQL 568

Query: 994  SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053
            +RIYPKG R+DSSNY P  +WN G Q+VALN+Q  D  M VN+G F+ NG  G++LKP+F
Sbjct: 569  TRIYPKGTRVDSSNYVPQIYWNAGCQLVALNFQCFDVAMCVNLGVFEYNGCSGYLLKPEF 628

Query: 1054 M--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDS-G 1110
            M   ++ ++P  + +++G V   T+ +++I A+ L        S +VEVE+ G   D+  
Sbjct: 629  MRKLDKRFDPFTESTVDGVVAG-TIEIKIISAQFLSDK---QISSYVEVEMYGLPTDTVR 684

Query: 1111 VKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168
             K  TKTV++NG++P +N+      +V  P+LA++R +V ++       FIG    PL  
Sbjct: 685  KKFKTKTVNNNGMDPYYNENAFVFKKVVLPDLAVVRIIVNEDG----GKFIGHRLMPLDG 740

Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHL 1195
            ++ GYR +PL N  +  L L+++  H+
Sbjct: 741  IKPGYRHIPLRNESNRPLGLASVFAHI 767


>UniRef50_Q4S530 Cluster: Chromosome 6 SCAF14737, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 6 SCAF14737, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 767

 Score =  171 bits (415), Expect = 1e-40
 Identities = 78/163 (47%), Positives = 109/163 (66%), Gaps = 2/163 (1%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           + T   F+  L+  +  I +  +    QDM +PL+HY+ISSSHNTYL  DQ    SS EA
Sbjct: 212 HMTKDGFLMYLHQDEGYILNPAHKHQYQDMRQPLNHYFISSSHNTYLMEDQLKGPSSTEA 271

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           Y+      CRC+ELDCWDGP+G P IYHG+T+T+K+ F DV++ IK++AF TS+YP+ILS
Sbjct: 272 YINTDEE-CRCVELDCWDGPNGEPIIYHGYTITSKVLFRDVIKAIKDYAFKTSQYPVILS 330

Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKN-ETSLPSPHD 443
           +E++CS+ QQ+ MA     + GD LL  P+ K+  +  PSP D
Sbjct: 331 LENHCSVDQQKLMAHHLISILGDALLTAPLGKSLPSEFPSPED 373



 Score = 89.8 bits (213), Expect = 4e-16
 Identities = 43/88 (48%), Positives = 60/88 (68%), Gaps = 1/88 (1%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            ++AKE+SD++IYC+SV F+      +   + EMSSF E+KA  L ++   T F+ ++  +
Sbjct: 426  KLAKELSDIVIYCKSVHFSSFEHARENQAFYEMSSFKESKAFSL-AETSATAFMHHNMDK 484

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQM 1020
            LSRIYP G R DSSNYNPVP WN G Q+
Sbjct: 485  LSRIYPAGSRTDSSNYNPVPMWNVGCQI 512



 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 42/123 (34%), Positives = 67/123 (54%), Gaps = 5/123 (4%)

Query: 1079 RVIGARHLCKTGR----GTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFE 1134
            +VI A+ L K  +        P V VE+ G   D+  K  T  +S+NG NP+WN   +F+
Sbjct: 646  QVISAQQLPKLNKDKQKSIVDPLVRVELYGVPADNASK-ETHHISNNGFNPMWNQRFQFD 704

Query: 1135 VANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
            +  PEL ++RFVV+D D   + + IGQ   PL  ++ GYR VP+     + +  + L ++
Sbjct: 705  IHVPELVMVRFVVEDYDATSQNDLIGQYCLPLTSIQNGYRHVPILTKRGDVISSAGLFLN 764

Query: 1195 LSI 1197
            L +
Sbjct: 765  LML 767



 Score = 47.2 bits (107), Expect = 0.003
 Identities = 41/206 (19%), Positives = 91/206 (44%), Gaps = 10/206 (4%)

Query: 1   MKSVCFNGAKDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           +K V     K RL  E D  + ++ +G  ++K       + R   ++ +  + +W   + 
Sbjct: 22  VKKVAQENGK-RLGLEGDADVQFLLQGGELVKVRSTTWKKMRFFKLQEDC-KTIWHESH- 78

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
            +R   +    I ++  +R G+ S+   +    T  ++  +CF+I +  + + +    +A
Sbjct: 79  -KRFNRDQTFSIDEIDSLRLGRQSEGLNK---HTHPVDEDQCFSIIF--KGRKKNLDLMA 132

Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKI 179
              +    WV G+  +I    + S+  + E W+       + N   K+ LKE+K FL +I
Sbjct: 133 PNGEVARKWVNGMEKIINNMRNLSHVQKSEHWIINCMRKADKNEDNKMNLKELKHFLRQI 192

Query: 180 NCKISTSKLRDVFQDVDTEKRGEIGF 205
           N +++     ++F+    +   + GF
Sbjct: 193 NIEVNDVYAEELFKQSTNKHMTKDGF 218


>UniRef50_O97035 Cluster: PLC-betaH1; n=1; Hydra magnipapillata|Rep:
            PLC-betaH1 - Hydra magnipapillata (Hydra)
          Length = 1012

 Score =  170 bits (414), Expect = 2e-40
 Identities = 108/264 (40%), Positives = 152/264 (57%), Gaps = 13/264 (4%)

Query: 936  KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995
            +E+S+L+ Y + V F       K   Y EMSSF E  A  L+ +Q    FV Y+  Q SR
Sbjct: 533  QELSELVNYFQPVHFRGFEKAEKRKCYYEMSSFGENTATNLLKEQP-VEFVNYNKFQNSR 591

Query: 996  IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM- 1054
            IYPKG R+ S NY P  FWN G QMVALN+QT D PMQ+N+GKF+ NG CG++LKP+ M 
Sbjct: 592  IYPKGSRVSSDNYIPQLFWNAGCQMVALNFQTLDVPMQLNLGKFEINGRCGYLLKPEHMR 651

Query: 1055 -FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDS-GVK 1112
              +  ++P    +++G +   TV ++VI  + L +   GT   +VEVE+ G   D+   K
Sbjct: 652  RHDLTFDPFVDSTVDGIIAG-TVQVKVISGQCLLERRSGT---YVEVEMYGLPADTVRRK 707

Query: 1113 LVTKTVSDNGLNPLWN-DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171
              TK VS+NGLNP+++ D  +F+V  P LA +R  V +E+       IG    P+  L  
Sbjct: 708  YRTKVVSNNGLNPVYDEDPFKFKVILPHLAELRIAVYEEN----GKMIGHRILPVDGLLP 763

Query: 1172 GYRSVPLTNAFSEELELSTLMVHL 1195
            G+R + L N   + L L TL V +
Sbjct: 764  GFRHIKLRNESYQPLCLPTLFVDI 787



 Score =  163 bits (397), Expect = 2e-38
 Identities = 119/370 (32%), Positives = 188/370 (50%), Gaps = 24/370 (6%)

Query: 92  EETKRLESSKCFTIYYGTEF-KLRCASFVAQTDKECEAWVKGVLYLIAEAVSA-SYPLQ- 148
           E    L   +  TI YG+ F  L   +FVA +  E + W + +       +   S PL+ 
Sbjct: 99  ELESNLMQERTITIVYGSNFVDLTFINFVASSVSEAQEWTEALFKCTNNLLEFHSSPLKC 158

Query: 149 IERWLRKEFYSIENSHEKITLKE-VKAFLP-KINCKISTSKLRDV---FQDVDTEKRGEI 203
           +ER+  +     +N + +I +K  VKAF+  K + K +   L+ +       D     + 
Sbjct: 159 LERFYTRICVQ-KNQNGEIPVKILVKAFVNHKEDIKRAYGTLQSLGIAHGKKDMIVLKDF 217

Query: 204 GFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDD---- 259
            F+ F   Y +LI   ++  ++F +      N   +T  +   FL + Q D   ++    
Sbjct: 218 SFETFFTFYNRLI-SRHDFDNVFTELGA--KNKPYLTTDQLVEFLNNRQRDPRLNEILFP 274

Query: 260 --EVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSH 317
              + A+  I +     +    +   ++   ++ L S   ++       + QD++ P++H
Sbjct: 275 YYNINAADAIVNTYEPNKSFADKGLISIDGLMKFLMSNDANVLLPGKLNIHQDLSFPIAH 334

Query: 318 YWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTT 375
           Y+I+SSHNTYL G Q + +SS+E Y + L +GCRCIELDCWDG   +  P I HG TL T
Sbjct: 335 YFINSSHNTYLQGHQLTGKSSVEIYRQVLLAGCRCIELDCWDGKTEEQEPVITHGMTLCT 394

Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE 435
           ++ F DV+  IKE AF TSEYP+ILS E++CS  QQ +MA+    +FGDLLL   +D+  
Sbjct: 395 EVLFKDVIEAIKESAFKTSEYPVILSFENHCSAKQQMKMANYCLQIFGDLLLNKELDEYP 454

Query: 436 ----TSLPSP 441
               T LPSP
Sbjct: 455 LLPGTLLPSP 464


>UniRef50_UPI000065E6FA Cluster:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            epsilon 1 (EC 3.1.4.11) (Phospholipase C-epsilon-1)
            (PLC-epsilon-1) (Phosphoinositide-specific phospholipase
            C epsilon-1) (Pancreas- enriched phospholipase C).; n=9;
            Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate
            phosphodiesterase epsilon 1 (EC 3.1.4.11) (Phospholipase
            C-epsilon-1) (PLC-epsilon-1) (Phosphoinositide-specific
            phospholipase C epsilon-1) (Pancreas- enriched
            phospholipase C). - Takifugu rubripes
          Length = 1761

 Score =  169 bits (412), Expect = 3e-40
 Identities = 88/205 (42%), Positives = 127/205 (61%), Gaps = 10/205 (4%)

Query: 243  EFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFVEMLYSKQNSIYD 301
            +  +FL + Q ++L  DE+ +   I+ +  +P   + +  + +   F   L  K N    
Sbjct: 833  QLNDFLVNCQREHLSYDEILS--IIQKF--EPSSSMRQMGWMSFEGFSRFLMDKDNFASH 888

Query: 302  SQYDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360
             +  ++  +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + L  GCR +ELDCWDG
Sbjct: 889  IEESQMNPEELQHPLSYYYIQSSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG 948

Query: 361  PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420
             DG P IYHGHTLTTKI F DV+  I   AF+ S  P++LSIE++CSLPQQR+MA  F+ 
Sbjct: 949  DDGMPVIYHGHTLTTKIPFKDVVEAISRSAFVNSNMPVVLSIENHCSLPQQRKMAEIFKT 1008

Query: 421  VFGDLLLVHPMDKNETS----LPSP 441
            VFG+ L+   + +++ S    LPSP
Sbjct: 1009 VFGERLVTRFLFESDFSDDPHLPSP 1033



 Score =  153 bits (372), Expect = 2e-35
 Identities = 84/234 (35%), Positives = 127/234 (54%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +      +++   QL R YP   RIDS+N NP+ FW  G Q+VALN
Sbjct: 1245 ISSVNENAAKRLCRRYSQKL-IQHTVCQLLRTYPAATRIDSTNPNPLLFWLHGIQLVALN 1303

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG---YNP-CDKKSIEGKVKPVTVMLRV 1080
            YQT D PMQ+N   F+ NGGCG++LKP  +++     Y   C  +    K+ P    L +
Sbjct: 1304 YQTDDLPMQLNTALFEANGGCGYVLKPAVLWDRNCPMYQQFCPMERDVEKMSPAVYSLAI 1363

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C  G  + SP +EV+++G   DS     TK +  N LNP+WN+  +F V   E+
Sbjct: 1364 VSGQNVC-PGNSSGSPCIEVDVLGMPVDS-AHFRTKPIHRNTLNPMWNEHFQFTVHFEEM 1421

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +R  V + +         Q T PL  L+ GYR + L    +E LE+S+L ++
Sbjct: 1422 CFLRVAVVENN---SSQTTAQRTLPLKALKSGYRHIQLRTQHNESLEVSSLFIY 1472


>UniRef50_A3LSB2 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1; n=2; Saccharomycetaceae|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1 - Pichia stipitis (Yeast)
          Length = 943

 Score =  169 bits (410), Expect = 5e-40
 Identities = 101/304 (33%), Positives = 161/304 (52%), Gaps = 32/304 (10%)

Query: 159 SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD--TEKRGEI-----GFDDFAVL 211
           S ++  E ++ +++  +  ++N  I+   LR +F +V    +K  E+      FD F + 
Sbjct: 314 SDKSVREFLSFEDILKYSKRLNININRGYLRSIFDEVKKVNDKEDEVCGNGLNFDQFKLF 373

Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271
              L        DI + +S+ C +G ++TL  F+ F+   Q D++  +     +  + + 
Sbjct: 374 VSTL----KKRSDIMEIWSLVCGSGQSMTLEIFKQFIIQVQKDSI--ENAVLHKIFKKFC 427

Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331
            D        Y+    F   L SK ++    Q +   Q M+ PLS Y+ISSSHNTYL G 
Sbjct: 428 VDTL-----DYWLPENFNNFLLSKYSTAIQ-QIEDEEQYMSYPLSEYYISSSHNTYLVGR 481

Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGP------------DGTPFIYHGHTLTTKIRF 379
           Q + +SS+E Y+R L+ GCRC+E+D WDG             D  P + HG T TT I F
Sbjct: 482 QVAGDSSVEGYIRALQRGCRCVEVDVWDGEVAESEEGVQFQHDKEPIVNHGRTFTTAISF 541

Query: 380 MDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLP 439
            +V+ TIK++AF TS YPL++S+E NCS+  QR++    ++  GD L+  P+  N T LP
Sbjct: 542 SNVISTIKKYAFFTSPYPLVISLEINCSVASQRKIVDILKNTLGDTLIATPILDNAT-LP 600

Query: 440 SPHD 443
           SP++
Sbjct: 601 SPNE 604



 Score =  107 bits (256), Expect = 2e-21
 Identities = 87/284 (30%), Positives = 137/284 (48%), Gaps = 23/284 (8%)

Query: 930  RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            ++ +I  E+SDL +Y + + F    L  +   YN   S  E     ++  +     +  H
Sbjct: 662  KSTKIIDELSDLGVYFQGLKFRNFSLP-ESKTYNHCFSLSEKSINSMLKDETKKASIDKH 720

Query: 990  TTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFI 1048
              + L R+YP   R+ SSN+ P+ +W  G QMVA N+QT D   Q++   F   G  G++
Sbjct: 721  NRRYLMRVYPSKIRVRSSNFLPLKYWEHGVQMVATNWQTYDLGQQISEAMFDSVGRKGYV 780

Query: 1049 LKPQFMFEEGYNPCDKKSIEGKVKPVTVMLR----VIGARHLCKT-GRGTA-SPFVEVEI 1102
            LK   + +       K+    K  P T  ++    +I A  L K+ G   A +PFV+ EI
Sbjct: 781  LKDTSLRKPLLKSLRKQ--VSKYSPGTFEVKFDFEIISAHQLPKSKGEENAINPFVQFEI 838

Query: 1103 IGA---DYDSGVKLV--TKTVSDNGLNPLWNDICEFEV-ANPELALIRFVV-----QDED 1151
            IGA   ++D     +  TK VS+NG NP WN     ++ A   L  ++F +     + E+
Sbjct: 839  IGATTIEWDDNSMALGKTKIVSENGFNPRWNQTFSGKMTAANNLVFVKFTIFASESKTEE 898

Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            I   P  IG     L  L++GYR + + + F EEL  S+L V +
Sbjct: 899  IEASP--IGICVARLNNLKRGYRYLNVNDLFGEELVYSSLFVKI 940


>UniRef50_P13217 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase; n=12; Pancrustacea|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase - Drosophila melanogaster (Fruit fly)
          Length = 1095

 Score =  169 bits (410), Expect = 5e-40
 Identities = 120/405 (29%), Positives = 210/405 (51%), Gaps = 34/405 (8%)

Query: 64  QGYEG-ALDIRDVKEVRTGKSSKDFERWPEETKRLESS------KCFTIYYGTEF-KLRC 115
           +G +G  +++  V ++R G + KD +   + TK+  ++      +  TI   T++  +  
Sbjct: 58  EGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITY 117

Query: 116 ASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQI---ERWLRKEFYSIENSHEKITLKEV 172
              +       ++W K +  +     + +   ++   + W+R   Y +E S  KI +K +
Sbjct: 118 HHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLS-YCVEKSG-KIPVKTL 175

Query: 173 -KAFLPKINCKISTSKLRDVFQDVD---TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDK 228
            K F      K+  + ++D     D   T  + +  FD F  LY K +   N+++++F  
Sbjct: 176 AKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHK-VCPRNDIEELFT- 233

Query: 229 YSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYEP 281
            S+       I+L +F  F+ D+Q D  + +      +E + ++ I DY  D ++     
Sbjct: 234 -SITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKK-KNV 291

Query: 282 YFTLSEFVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLE 340
             +L  F   L S +N+ ++  + D    +M +PL+HY+I+SSHNTYL+G Q   +SS+E
Sbjct: 292 QMSLDGFKRYLMSDENAPVFLDRLD-FYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVE 350

Query: 341 AYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
            Y + L +GCRC+ELDCW+  G D  P + HGH   T+I F D ++ I + AF++SEYP+
Sbjct: 351 MYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPV 410

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKN--ETSLPSP 441
           ILS E++C+  QQ ++A    D FGDLLL  P+  +  +  LP P
Sbjct: 411 ILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLP 455



 Score =  165 bits (402), Expect = 5e-39
 Identities = 101/265 (38%), Positives = 152/265 (57%), Gaps = 14/265 (5%)

Query: 938  ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997
            +S ++ Y + + F      I+  + + MSSF E+     + +Q +  FV Y+  Q+SRIY
Sbjct: 550  LSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYL-KQSSIDFVNYNKRQMSRIY 608

Query: 998  PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055
            PKG R DSSNY P  FWN G QMV+LN+Q+ D PMQ+N GKF+ NGGCG++LKP FM   
Sbjct: 609  PKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRA 668

Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK-LV 1114
            ++ ++P     ++G V      ++VI  + L     GT   +VEV++ G   D+  K   
Sbjct: 669  DKDFDPFADAPVDG-VIAAQCSVKVIAGQFLSDKKVGT---YVEVDMFGLPSDTVKKEFR 724

Query: 1115 TKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172
            T+ V++NGLNP++N D   F +V  P+LA++RF V +E        +GQ   PL  L+ G
Sbjct: 725  TRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEE----SGKILGQRILPLDGLQAG 780

Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197
            YR V L    +  + L  L V++ +
Sbjct: 781  YRHVSLRTEANFPMSLPMLFVNIEL 805


>UniRef50_P25455 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase classes I and II; n=10;
           Endopterygota|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase classes I and II - Drosophila
           melanogaster (Fruit fly)
          Length = 1318

 Score =  168 bits (409), Expect = 7e-40
 Identities = 123/390 (31%), Positives = 199/390 (51%), Gaps = 33/390 (8%)

Query: 70  LDIRDVKEVRTG---KSSKDFER------WPEETKRLESSKCFTIYYGTEF-KLRCASFV 119
           LDI  +++VRTG   K  KD +        P++T  LE  K  T+ +G++F  +   +F 
Sbjct: 62  LDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDT--LEE-KTVTVCHGSDFVNMTFVNFC 118

Query: 120 AQTDKECEAWVKGVL---YLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFL 176
                  + W  G++   Y +A+ ++ S  + +++   K    ++ S        +K F 
Sbjct: 119 CTRRDIAQLWTDGLIKLAYSLAQ-LNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFA 177

Query: 177 PKINCKISTSKLRDVFQ----DVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVY 232
                +    K  DV       VD+    +  F+DF  LY K +   + V+ +FD   V 
Sbjct: 178 QNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLY-KYLTQRSEVERLFDSI-VG 235

Query: 233 CSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQR-DIYEPYFT 284
            S    +++ +   FL   Q D  L +      +  +A + I+ Y  +P + +  +   +
Sbjct: 236 NSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQY--EPNKFNAQKGQLS 293

Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344
           L  F+  L    N I       +  DM +P+SHY+I+SSHNTYLTG Q + +SS+E Y +
Sbjct: 294 LDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQ 353

Query: 345 CLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404
           CL +GCRC+ELD W+G    P I HG+T   +I   DVL  I E AF TSEYP+ILS E+
Sbjct: 354 CLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFEN 413

Query: 405 NCSLPQQRRMASAFQDVFGDLLLVHPMDKN 434
           +C+  QQ ++A+  +++FGD+LL  P+D +
Sbjct: 414 HCNPRQQAKIANYCREIFGDMLLDKPLDSH 443



 Score =  154 bits (374), Expect = 1e-35
 Identities = 101/273 (36%), Positives = 150/273 (54%), Gaps = 16/273 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985
            K ++      EIS L+ Y + + F+  E    K   Y EMSSF E +A  L+ ++   F 
Sbjct: 588  KAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCY-EMSSFDEKQATTLLKERPIEF- 645

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            V Y+  QLSR+YP G R DSSN+ P  FWN G Q+VALN+QT D  MQ+N+G F+ N   
Sbjct: 646  VNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARS 705

Query: 1046 GFILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEII 1103
            G++LKP+FM   +   +P  + +++G +   TV + V+  + L       A+ FVEV++ 
Sbjct: 706  GYLLKPEFMRRSDRRLDPFAESTVDGIIAG-TVSITVLSGQFLTDK---RANTFVEVDMY 761

Query: 1104 GADYDS-GVKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160
            G   D+   K  TKTV DNG+NPL+++      +V  PELA IR    +E        IG
Sbjct: 762  GLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEG----GKLIG 817

Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
                P++ L  GYR V L +   + + L++L +
Sbjct: 818  HRVLPVIGLCPGYRHVNLRSEVGQPIALASLFL 850


>UniRef50_A4IGD0 Cluster: Plcb3 protein; n=11; Euteleostomi|Rep:
           Plcb3 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 557

 Score =  168 bits (408), Expect = 9e-40
 Identities = 127/430 (29%), Positives = 205/430 (47%), Gaps = 32/430 (7%)

Query: 70  LDIRDVKEVRTGKSSKD--FERWPE-----ETKRLESSKCFTIYYGTEF-KLRCASFVAQ 121
           LD+  +++ RTGK +K    +R  E     +      S+  T+ YG +   +   +F A 
Sbjct: 66  LDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAV 125

Query: 122 TDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KAFLP 177
            D  C+ W   +  L    +S +       +L K +  ++       KI +K + K F  
Sbjct: 126 QDGYCKLWTDELFKLATNMLSQN--ASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD 183

Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237
           K   +++      +F  VD  K  +  ++ F     KL      V+ IF    +      
Sbjct: 184 KKRAEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLS-PRPEVERIF--VDLGSKGKP 240

Query: 238 TITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSEFVE 290
            ++L +  +F+  +Q D+  ++ +       Q  Q +  Y  +  + +     +L  F +
Sbjct: 241 FLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQ-LERDQISLMSFTK 299

Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350
            L  ++N++   +   +  DM +PLSHY+I+SSHNTYLT  Q +  SS+E Y + L +GC
Sbjct: 300 YLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGC 359

Query: 351 RCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-S 407
           RCIELDCW G  P+  P I HG T+TT+I F DV+  I E AF TS YPLILS E++  S
Sbjct: 360 RCIELDCWKGRPPEEEPTITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDS 419

Query: 408 LPQQRRMASAFQDVFGDLLLVHPMDKNE----TSLPSPHDXXXXXXXXXXXXPEGAEESS 463
             QQ +MA   + +FGD LL+ P+DK        LPSP +                  + 
Sbjct: 420 AKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNG 479

Query: 464 FAVRQEEGKD 473
            ++R+++G D
Sbjct: 480 GSIRRKDGTD 489


>UniRef50_Q4S9T4 Cluster: Chromosome 2 SCAF14695, whole genome shotgun
            sequence; n=2; Tetraodontidae|Rep: Chromosome 2
            SCAF14695, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1095

 Score =  167 bits (406), Expect = 2e-39
 Identities = 97/242 (40%), Positives = 139/242 (57%), Gaps = 9/242 (3%)

Query: 962  YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021
            Y  + S  E +A RL ++      V +    L+R+ P   R+DSSN NP  +W  G Q+V
Sbjct: 630  YWTLCSLGEGEAGRLTTESPEDL-VTFTKRTLTRVRPSSVRLDSSNPNPQGYWKGGLQLV 688

Query: 1022 ALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE-GYNPCDKKSIEGKVKPVTVMLRV 1080
            ALN QTP   + +N G+F QNGGCG++L+P  M +E  Y     +     V P T+ ++V
Sbjct: 689  ALNQQTPGAMLDINRGRFSQNGGCGYVLRPAVMRDEVSYFSAHTQGCVPGVPPQTLRIKV 748

Query: 1081 IGARHLCK-TGRG----TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEV 1135
            I A  L K  G G       P+V +E+ G   D   +  T+T + N  +PL+++  EF+V
Sbjct: 749  ISAHSLPKPIGSGAKGEVIDPYVVLELHGVPADCAEQR-TRTAAQNQDDPLFDETFEFQV 807

Query: 1136 ANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
              PELAL+RFVV D+D  G+ +FIGQ T P  CL+ GYRSVPL     ++L  S+L VH+
Sbjct: 808  NMPELALLRFVVLDDDYIGD-DFIGQYTVPFECLQPGYRSVPLLGMAGDQLPHSSLFVHV 866

Query: 1196 SI 1197
            +I
Sbjct: 867  AI 868



 Score =  130 bits (315), Expect = 2e-28
 Identities = 131/520 (25%), Positives = 218/520 (41%), Gaps = 64/520 (12%)

Query: 2   KSVCFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60
           K+V F+    ++ +  A   +++++ G  + K  P  R   R   +  +   + W     
Sbjct: 35  KTVSFSSMPSEKKVSSAADCLAFMQGGCELKKIRPNSRIYCRFYTLDPDLSCLRWE---P 91

Query: 61  PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120
            ++ G    LD+  V+EVRTGKS++ F      +++L     F+I +G +++      VA
Sbjct: 92  SKKDGERARLDVSSVREVRTGKSTETFLHNGLPSEQLAEEAAFSIIHGDDYQ--SLDLVA 149

Query: 121 QTDKECEAWVKGVLYLIAE------------AVSASYPLQIER---------WLRKEFYS 159
            +      WV G+ YL+A               S    L +E          WL  EF  
Sbjct: 150 FSADVANIWVTGLRYLLAHPSIVGGGGGGGGVFSEGGGLVVEGSLGGKMRSDWLSAEFAQ 209

Query: 160 IENSHEKITLKEVKAF-LPKINCKISTSKLRDVFQDVDTEKR---GEIGFDDFAVLYQKL 215
           ++     I  ++V    + K+   I  +K+R  F+++   K      +  ++F   Y +L
Sbjct: 210 VDEDGYGIVSEDVAVTTICKLCPGIKEAKVRLRFKEIQRSKEKLTSHVTCEEFQEAYCEL 269

Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275
                   D++        +   +  ++ + FL  EQ  +L   E    + +R Y  +P 
Sbjct: 270 C----TRPDVYFLLVQLSKDRECLDPQDLRLFLETEQGLSLVTTE-GCLELLRRY--EPS 322

Query: 276 RDIYEP-YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334
               E     L      L S +  ++D ++ +V QDMT PLSHY+IS+S+ +YL  DQ  
Sbjct: 323 AQAREKGLLGLDGLTRYLQSSECHLFDPEHLEVCQDMTMPLSHYYISTSYRSYLLDDQVH 382

Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFI-------------------YHGHTLTT 375
           +       ++ L+SGCRC+EL   DGP+G P +                   +H H   T
Sbjct: 383 A-GRPRGLIKALQSGCRCVELGVTDGPEGEPLLGVDYGPDISRQHHHHHHHHHHHHHQHT 441

Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-----LVHP 430
            I     L  I ++AF+TS+YPL+L +   CS  QQR MA   + V G  L     L   
Sbjct: 442 PITIRSALEVINKYAFLTSQYPLLLYLCHRCSPAQQRTMAQHLKKVLGSRLYTPEALPVS 501

Query: 431 MDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEE 470
           +    T+LP+P                  E S   V +EE
Sbjct: 502 LGGRATTLPTPEQLRGRVLLVGKKLSPDQETSEGEVSEEE 541


>UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 2 SCAF15106, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1617

 Score =  167 bits (405), Expect = 2e-39
 Identities = 83/165 (50%), Positives = 105/165 (63%), Gaps = 5/165 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR-PLSHYWISSSHNTYLTGDQFSSESSLE 340
           + +   F   L  K N        ++ Q+  R PLS+Y+I SSHNTYLTG Q   ESS+E
Sbjct: 804 WMSFEGFSRFLMDKDNFASCIDESQMNQEELRYPLSYYYIQSSHNTYLTGHQLKGESSVE 863

Query: 341 AYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLIL 400
            Y + L  GCR +ELDCWDG DG P IYHGHTLTTKI F DV+  I   AF+ S  P+IL
Sbjct: 864 LYSQVLLQGCRSVELDCWDGDDGMPVIYHGHTLTTKIPFKDVVEAISRSAFVNSNMPVIL 923

Query: 401 SIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
           SIE++CSLPQQR+MA  F+ VFG+ L+   +  ++ S    LPSP
Sbjct: 924 SIENHCSLPQQRKMAEIFKTVFGERLVTRFLFDSDFSDDPHLPSP 968



 Score =  151 bits (367), Expect = 9e-35
 Identities = 84/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +      +++   QL R YP   RIDS+N NP+ FW  G Q+VALN
Sbjct: 1214 ISSVNENAAKRLCRRYSQKL-IQHTACQLLRTYPAATRIDSTNPNPLLFWLHGIQLVALN 1272

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE---GYNP-CDKKSIEGKVKPVTVMLRV 1080
            YQT D PMQ+N   F+ NGGCG++LKP  +++     Y   C  +    K+ P      +
Sbjct: 1273 YQTDDLPMQLNTSLFEANGGCGYVLKPAVLWDRNCLNYQQFCPMERDVEKMSPAVYSFTI 1332

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C  G  + SP +EV+++G   DS     TK +  N LNP+WN+  +F V   E+
Sbjct: 1333 VSGQNVC-PGNSSGSPCIEVDVLGMSVDS-AHFRTKPIHRNTLNPMWNEHFQFTVHFEEM 1390

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +R  V + +         Q T PL  L+ GYR + L    +E LE+S+L V+
Sbjct: 1391 CFLRVAVVENN---SSQTTAQRTLPLKALKSGYRHIQLRTQHNEFLEVSSLFVY 1441


>UniRef50_Q16ZC0 Cluster: Phospholipase c epsilon; n=1; Aedes
           aegypti|Rep: Phospholipase c epsilon - Aedes aegypti
           (Yellowfever mosquito)
          Length = 1022

 Score =  167 bits (405), Expect = 2e-39
 Identities = 81/158 (51%), Positives = 107/158 (67%), Gaps = 4/158 (2%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F   +  K N  + S+    +  M  PLS Y+I+SSHNTYLTG Q   ESS+E Y + L 
Sbjct: 19  FARYMMDKDNYAFLSELMPESTYMNLPLSQYYIASSHNTYLTGHQLKGESSVELYSQVLL 78

Query: 348 SGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407
           +G RC+ELDCWDG DGTP IYHGHT TTKI F  V+  I + AF+ S YP+ILSIE++CS
Sbjct: 79  TGARCVELDCWDGDDGTPVIYHGHTFTTKIPFRAVVEAINKSAFVQSAYPVILSIENHCS 138

Query: 408 LPQQRRMASAFQDVFGDLLLVHPM-DKNETS---LPSP 441
           + QQ+RMA+ FQ +FG+ L+ + + D++ T    LPSP
Sbjct: 139 VTQQQRMAAIFQAIFGEKLVTNFLFDQDYTDEPYLPSP 176



 Score =  142 bits (344), Expect = 5e-32
 Identities = 81/236 (34%), Positives = 129/236 (54%), Gaps = 15/236 (6%)

Query: 964  EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023
            + SS  E  A++L  +++    + +  TQL R YP G RIDSSN+NPV FW+ G QMVAL
Sbjct: 406  QCSSLNEASAKKLC-RKDPLGLIAHTETQLMRTYPAGLRIDSSNFNPVFFWSFGFQMVAL 464

Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG------YNPCDKKSIEGKVKPVTVM 1077
            NYQT D PM +N   F++N  CG++ KP  ++         +NP +K+  +G +    ++
Sbjct: 465  NYQTEDMPMHINKAMFEENNSCGYVRKPDVLWNRSHLMYRRFNPLEKE-FDG-LHVTQLV 522

Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137
            + V+  ++L     G     VE+E++G   D G +  TK V  N  NP+WN+   F++  
Sbjct: 523  INVVSGQYLNHVTGGNVI-HVEIELLGIPIDCG-RRRTKPVKHNLFNPVWNETFFFKIMF 580

Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
             +LA ++F V +     E   + Q    L C R GYR V L +  ++ L +++L +
Sbjct: 581  HDLAFLKFTVYE----SESVVVAQRVISLKCFRPGYRHVRLRSPINQPLNMASLFL 632


>UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
            phosphodiesterase epsilon-1; n=28; Amniota|Rep:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            epsilon-1 - Homo sapiens (Human)
          Length = 2302

 Score =  167 bits (405), Expect = 2e-39
 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%)

Query: 288  FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
            F   L  K+N  S  D   + + +++  PLS+Y+I SSHNTYLTG Q   ESS+E Y + 
Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428

Query: 346  LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
            L  GCR +ELDCWDG DG P IYHGHTLTTKI F +V+  I   AFI S+ P+I+SIE++
Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488

Query: 406  CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441
            CSLPQQR+MA  F+ VFG+ L+   + + + S    LPSP
Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528



 Score =  145 bits (351), Expect = 7e-33
 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E  A+RL  +       ++   QL R YP   RIDSSN NP+ FW  G Q+VALN
Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080
            YQT D P+ +N   F+ NGGCG++LKP  ++++      K S +E     + P    L +
Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875

Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
            +  +++C +     SP +EV+++G   DS     TK +  N LNP+WN+   F V   +L
Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194
              +RF V + +         Q   PL  L++GYR + L N  +E LE+S+L ++
Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984


>UniRef50_A7S279 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1125

 Score =  165 bits (402), Expect = 5e-39
 Identities = 119/398 (29%), Positives = 193/398 (48%), Gaps = 32/398 (8%)

Query: 69  ALDIRDVKEVRTGKSSKDFERWPEETKRLESS----KCFTIYYGTEF-KLRCASFVAQTD 123
           +++I ++ EVR G   KD ++  E  +R  +     + FT+ Y T           A T 
Sbjct: 65  SIEISNISEVRLGVLPKD-QKVRESLQRTGADPLEERGFTVVYNTNLVDCNYLHLFASTS 123

Query: 124 KECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKI 183
           +  + WV+G+  L+      +  +  +  L K++       + +    VK+    +    
Sbjct: 124 RVAKEWVEGLRPLLHNVRLDNCSVLTQ--LHKQYVKAGLHKDALGKISVKSICKALYAGK 181

Query: 184 STSKLRDVFQDV-------DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNG 236
             S + D  Q +       D     +  F+ F  LY K +     + ++  ++       
Sbjct: 182 FESLVLDALQALGLPCSKNDKITPEDFTFEHFYQLYLK-VCPRLEIMELCVEWGG--GRA 238

Query: 237 TTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYE-PYFTLSEF 288
             +T  +  NF+  EQ D  L +      D  +A   I  Y  + Q D+ +     ++  
Sbjct: 239 PILTATQLVNFMNKEQRDPRLNEILFPFCDNEKALSLIWKY--EKQMDMLQRDRICVNGL 296

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
              L S+ N +       ++ DM +PLSHY+I+SSHNTYL G QF   SS+E Y +CL +
Sbjct: 297 TRYLLSEDNLLIMPGRLNLSDDMNQPLSHYFINSSHNTYLVGRQFGGRSSVEMYRQCLIA 356

Query: 349 GCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSL 408
           GCRCIELDCWDG +  P I HG+ + TKI F DV+  I++ AF TS++P+ILS E++CS 
Sbjct: 357 GCRCIELDCWDGQNDEPIITHGNAMCTKILFKDVIEAIRDSAFQTSDFPVILSFENHCSK 416

Query: 409 PQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPH 442
            QQ +MA    D+ GD+L+  P++    +    LPSP+
Sbjct: 417 HQQYKMACYCMDILGDMLVTKPLESCPLEEGRPLPSPN 454



 Score =  160 bits (388), Expect = 2e-37
 Identities = 104/272 (38%), Positives = 150/272 (55%), Gaps = 14/272 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S L+ Y + V F       K  ++ +MSSF E+    L+ +     FVKY+ 
Sbjct: 559  TGNINPLLSSLVNYIQPVPFQGFDESEKRNLFYQMSSFNESTGFGLV-RATPLDFVKYNK 617

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q+SRIYP+G R+DSSNY P  FWN G QMV+LN+QTPD P  +N GKF+ NG  G+ILK
Sbjct: 618  RQMSRIYPRGSRVDSSNYMPQVFWNVGCQMVSLNFQTPDLPFHLNQGKFEFNGRSGYILK 677

Query: 1051 PQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P  M  +   ++P  +  I+G V    V ++VI  ++L      T    VEV++ G   D
Sbjct: 678  PDLMRRDDRMFDPFTESPIDGYV-GAYVAIKVISGQYLSDKKITTV---VEVDMYGLPTD 733

Query: 1109 S-GVKLVTKTVSDNGLNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +   K  TK+ + NGLN L++   +    V  PE+AL+RF V D++       I Q   P
Sbjct: 734  TIRKKYKTKSSTSNGLNTLYDGEHMVFRRVVLPEMALLRFAVIDDN----DRIIAQRVVP 789

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  ++ GYR VPL       + L+TL VH+++
Sbjct: 790  LDSIQAGYRHVPLRTENDTPIPLATLFVHITL 821


>UniRef50_Q4FXB0 Cluster: Phosphatidylinositol-specific
           phospholipase-like protein; n=3; Leishmania|Rep:
           Phosphatidylinositol-specific phospholipase-like protein
           - Leishmania major strain Friedlin
          Length = 729

 Score =  165 bits (400), Expect = 9e-39
 Identities = 100/289 (34%), Positives = 153/289 (52%), Gaps = 23/289 (7%)

Query: 157 FYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLI 216
           F + +    K++  E+     K+  ++  ++L D F+  D++K   + + +F   ++   
Sbjct: 150 FIAAQQGKTKLSFTEISMLTNKLFGRVPAAELADRFRQCDSDKDTCLNYQEFCEFFR--Y 207

Query: 217 FDENN-VQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275
           F+E   V+ I+++++  C+ G  +T  EF  F               AS F     R   
Sbjct: 208 FNEAKAVRSIYERHTSECAPG--MTAEEFTRFCISNDAAATVTPMRCASLFHLFANRQSD 265

Query: 276 RDIYEPYFTLSEFVE-MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334
           R        LS F   +L+   NSI D++  ++T  M  PL HY+I+SSHNTYLTG+Q +
Sbjct: 266 R------MALSGFTAFLLHPHHNSIVDARQLRLTDSMDHPLPHYFINSSHNTYLTGNQLN 319

Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFIT- 393
           SESS   Y   L +GCRC+E+DCWDGP G P +YHGHT+TTKI F DV+RTI ++AF   
Sbjct: 320 SESSCNMYRDVLLAGCRCVEIDCWDGPAGVPVVYHGHTMTTKIAFDDVVRTINDYAFQNP 379

Query: 394 ----------SEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432
                      E P+I+S+E + S  Q  RMA   + VF + L +  +D
Sbjct: 380 SNNQEAAWNPRELPVIVSLEVHTSPEQTNRMAEIIRSVFKERLFLSRLD 428



 Score =  112 bits (269), Expect = 6e-23
 Identities = 74/218 (33%), Positives = 110/218 (50%), Gaps = 15/218 (6%)

Query: 985  FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKF-KQNG 1043
            F + +T  LSRIYP G RIDSSNY+P+  W  G Q+VALN+QT D   +VN G F  QNG
Sbjct: 519  FARQNTHMLSRIYPSGTRIDSSNYDPMLMWRLGCQLVALNWQTRDHNFRVNEGFFTHQNG 578

Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEI- 1102
            GCG++LKP ++ +     C          P T+ LR+I   HL  T  G  +  V + + 
Sbjct: 579  GCGYVLKPMYLRDVDAG-C-------SAVPFTLALRLICGSHLSTTFDGADATHVTLRLR 630

Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
            +  +  S   +   T     + P WN+  E +    E A++   V      G  + +  A
Sbjct: 631  VHGEAWSHETIAVPTT----IYPEWNESMELQGKCKETAVLCLCVVAHTRSGATHDVCTA 686

Query: 1163 TFPLLCLRKGYRSVPLTNAFS-EELELSTLMVHLSIIT 1199
              P+  LR GY ++PL +  S    E+++++ H S  T
Sbjct: 687  CLPVRVLRTGYHAMPLRHVKSGRTAEVASVLCHFSFKT 724


>UniRef50_Q9NQ66 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
            phosphodiesterase beta-1; n=116; Eumetazoa|Rep:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            beta-1 - Homo sapiens (Human)
          Length = 1216

 Score =  165 bits (400), Expect = 9e-39
 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S+L+ Y + V   +F I + R K F   EMSSF ETK    +++     FV+Y+  Q
Sbjct: 538  EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            LSRIYPKG R+DSSNY P  FWN G QMVALN+QT D  MQ+NMG ++ NG  G+ LKP+
Sbjct: 594  LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ ++P  +  ++G V   T+ +++I  + L     GT   +VEV++ G   D+ 
Sbjct: 654  FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709

Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             K   TKT   N +NP+W +  I   +V  P LA +R  V +E       FIG    P+ 
Sbjct: 710  RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +R GY  + L N  ++ L L  + V++ +
Sbjct: 766  AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795



 Score =  147 bits (355), Expect = 2e-33
 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F+  L  ++N +   +   + +DM++PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           SGCRC+ELDCW G   +  P I HG T+TT+I F +V+  I E AF TS +P++LS E++
Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414

Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443
              P QQ +MA   + +FGD LL+ P++K    +   LPSP D
Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457


>UniRef50_Q9TVI2 Cluster: Putative uncharacterized protein plc-1; n=4;
            Caenorhabditis|Rep: Putative uncharacterized protein
            plc-1 - Caenorhabditis elegans
          Length = 1898

 Score =  164 bits (398), Expect = 1e-38
 Identities = 73/119 (61%), Positives = 90/119 (75%)

Query: 309  QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
            +D+  PLSHY+I+SSHNTYLTG Q    SS E Y + L +GCRC+ELDCWDG DG P IY
Sbjct: 910  EDLRYPLSHYYINSSHNTYLTGHQLKGPSSSEMYRQVLLTGCRCVELDCWDGDDGLPLIY 969

Query: 369  HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL 427
            HGHTL +KI F  V+  IK+ AFITS+ P+ILSIE++CSL QQ +MA  F+ V GDLL+
Sbjct: 970  HGHTLVSKIGFRQVVEIIKKSAFITSDLPVILSIENHCSLQQQAKMAQMFKTVLGDLLV 1028



 Score =  132 bits (320), Expect = 4e-29
 Identities = 78/220 (35%), Positives = 118/220 (53%), Gaps = 11/220 (5%)

Query: 964  EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023
            +++S  E  A++LM +      V Y    L R YP  +  DSSN+NP+  W  G QMVAL
Sbjct: 1296 QVTSLNENAAKKLMKRHPAKC-VSYTRDHLIRTYPSAKHYDSSNFNPINCWAHGMQMVAL 1354

Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK-----KSIEGKVKPVTVML 1078
            N+QTPD  M VN   F+Q+G CG+ LKP+ +++E +   +K     K I G    + + L
Sbjct: 1355 NFQTPDVIMAVNQAMFEQSGNCGYQLKPRCLWDESHLLYNKFLPLSKDIAGH-SALLLNL 1413

Query: 1079 RVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANP 1138
             +I  +H+       AS +VE+E+IG   D  V+  +K V  N +NP+WN   +  +A  
Sbjct: 1414 TIISGQHVYPNTH-YASLYVEIEVIGIHNDC-VREKSKVVQRNSVNPIWNHTTQLRIACV 1471

Query: 1139 ELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
            +LA +R  V D    G    +     P+ C+R G+R +PL
Sbjct: 1472 DLAFLRIAVCDSGQNG--RVVAHRVVPVKCIRPGFRHLPL 1509


>UniRef50_Q4Q6Z7 Cluster: Phospholipase c-like protein; n=2;
           Leishmania|Rep: Phospholipase c-like protein -
           Leishmania major
          Length = 560

 Score =  163 bits (395), Expect = 3e-38
 Identities = 97/252 (38%), Positives = 141/252 (55%), Gaps = 18/252 (7%)

Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237
           ++N +IS   L D+ +  D    G +   +F  L+ +L   E  ++ +F  ++       
Sbjct: 4   RMNVEISDDLLADLVRKHDASGDGALDLKEFTTLFIQLTQHEE-LRPLFASFAAQVD--- 59

Query: 238 TITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSK-Q 296
            +T  EF  FL+ +     GD    +S  + + L+ P ++      T ++FV  L S   
Sbjct: 60  WMTRAEFDCFLKAQ-----GD---VSSDVLFNTLK-PDKN---GRITFTQFVHYLLSPCL 107

Query: 297 NSIYDSQYDK-VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355
           N   D  +   V  +MT PL  Y+I+SSHNTYL+GDQF S S +E Y R L +GCRC+EL
Sbjct: 108 NPALDPAHQTGVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSRIEMYRRALLAGCRCVEL 167

Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415
           DCWDG D  P IYHGHT T+KIRF DV+ TI+ HAF  S +P+ILS+E + S  Q   MA
Sbjct: 168 DCWDGKDNDPVIYHGHTRTSKIRFADVIETIRRHAFTASPFPVILSLEVHTSDEQSMVMA 227

Query: 416 SAFQDVFGDLLL 427
              + + GD+L+
Sbjct: 228 GHLRTILGDMLM 239



 Score =  128 bits (309), Expect = 9e-28
 Identities = 76/218 (34%), Positives = 113/218 (51%), Gaps = 16/218 (7%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            + S+ ET  + L     + F +   +  L R+YPKG RI SSNYNP   W+ G+Q+VALN
Sbjct: 328  IQSYVETVVKELALGHRDEF-IGQTSRMLVRVYPKGTRIGSSNYNPTTAWSVGAQLVALN 386

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084
            YQT D  M++N G F  N GCG++LKP ++     NP  K     K  P T+ + V+   
Sbjct: 387  YQTWDDDMRLNDGMFSLNKGCGYVLKPDYL----RNPSGK----AKATPCTITVTVLSGT 438

Query: 1085 HLCKTG---RG-TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140
             + K     +G    P+V++ I   D     ++ T  V +NGLNP W +       + E+
Sbjct: 439  QIPKPSLQKKGDITDPYVKLYINKRD---RTEVKTSVVRNNGLNPYWMETFTLACESKEI 495

Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
             L+   V DED     + + +   P+  LR GYR+VP+
Sbjct: 496  GLLTVKVMDEDTTSANDSVCEMVIPVRALRTGYRAVPM 533


>UniRef50_Q95X29 Cluster: Egg laying defective protein 8, isoform b;
            n=5; Caenorhabditis|Rep: Egg laying defective protein 8,
            isoform b - Caenorhabditis elegans
          Length = 1431

 Score =  160 bits (389), Expect = 2e-37
 Identities = 110/275 (40%), Positives = 154/275 (56%), Gaps = 15/275 (5%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990
            T  I   +S L+ Y   V F+   +     ++  MSSF E+     + Q    F V Y+ 
Sbjct: 751  TTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEF-VNYNK 809

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
             Q SRIYPKG R+DSSN+ P  FWN G QMV+LN+QTPD  MQ+NMGKF+ NGG G++LK
Sbjct: 810  RQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLK 869

Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108
            P F+   +  ++P  +  ++G V      +RVI  + L     GT   +VEVE+ G   D
Sbjct: 870  PDFLRRPDRTFDPFSESPVDG-VIAAHCSVRVISGQFLSDRKIGT---YVEVEMYGLPTD 925

Query: 1109 SGVK-LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
            +  K   TK +  NGLNP++N D   F +V  PELA++RF V DE+  G+   +GQ   P
Sbjct: 926  TIRKEHKTKVIPGNGLNPVYNEDPFVFRKVVLPELAVLRFAVYDEN--GKQ--LGQRILP 981

Query: 1166 LLCLRKGYRSVPLTNAFSEELELS-TLMVHLSIIT 1199
            L  L+ GYR + L +  ++   LS  L V + I T
Sbjct: 982  LDGLQAGYRHISLRSDTNQSFILSPVLFVQIVIKT 1016



 Score =  158 bits (383), Expect = 1e-36
 Identities = 104/274 (37%), Positives = 147/274 (53%), Gaps = 20/274 (7%)

Query: 182 KISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITL 241
           K S  + R   +++D +    + F+ F  LY K I     VQ++F K S        +T 
Sbjct: 214 KCSRGRKRKEREELDVDI---LTFEKFQRLYNK-ICPRTEVQELFVKLS---GQKEYLTK 266

Query: 242 REFQNFLRDEQHDNLGDDEVQA---SQFIRDYLRDPQRDI-YEPYFTLSE--FVEMLYSK 295
               NFL +EQ D   ++ +     SQ I   L+  + DI Y+    +S   F+  L S 
Sbjct: 267 ERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSD 326

Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355
           +N        ++  DM +PL HY+I+SSHNTYLTG Q+  +SS E Y + L SGCRCIEL
Sbjct: 327 ENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIEL 386

Query: 356 DCWDGP---DGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQR 412
           DCWDG     G P I HG  + T + F DVL  I++ AF  S++P++LS E++CS   Q 
Sbjct: 387 DCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQL 446

Query: 413 RMASAFQDVFGDLLLVHPMDKNE----TSLPSPH 442
           +MA    D+FGD+LL  P +        SLPSP+
Sbjct: 447 KMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPN 480


>UniRef50_A0C336 Cluster: Chromosome undetermined scaffold_146,
           whole genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_146,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 709

 Score =  160 bits (388), Expect = 2e-37
 Identities = 103/303 (33%), Positives = 163/303 (53%), Gaps = 24/303 (7%)

Query: 131 KGVLYLIAEAVSASYPLQI--ERW---LRKEFYSIENSHEKITLKEVKAFLPKINCKIST 185
           +G+ YL+AEA      L    + W   L+    S  +   +++ KE +  + ++  +I  
Sbjct: 97  EGLQYLMAEAFRIQKQLDSYNQIWSNALKLITKSDLDMDNRLSFKEFQFLIGELQIEIPE 156

Query: 186 SKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245
            KL  +F     +K  ++   D A LY KL+ +     ++   Y  YCS    I   +  
Sbjct: 157 RKLLQLFDK--HQKNNQL---DEATLY-KLLMEITRKHELIQLYQKYCSKQEGI-FDDPH 209

Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYD 305
           N +    HD      ++  Q  +DY    Q+  Y  Y    +F  ++++++NSI+ ++  
Sbjct: 210 NTMLMSAHDLETFFLIEQGQ--KDY--KAQKQCYNFY----DFQNIIFNQENSIFQAK-- 259

Query: 306 KVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365
               D ++PL+ Y I+SSHNTYL  +Q + +SS  AY    + G +C+ELDCWDG DG P
Sbjct: 260 --DFDKSQPLTQYLINSSHNTYLETNQLTGQSSCFAYQDAFKMGFKCVELDCWDGQDGEP 317

Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425
            + HGHTL   I+F+DV+RT++E AFI  + P ILS+E +CSL QQRR+A   + V GD+
Sbjct: 318 NVTHGHTLVNDIKFIDVIRTVREFAFIKDDNPAILSLEMHCSLKQQRRIADIIRSVLGDM 377

Query: 426 LLV 428
           L V
Sbjct: 378 LFV 380



 Score =  104 bits (250), Expect = 1e-20
 Identities = 74/240 (30%), Positives = 123/240 (51%), Gaps = 29/240 (12%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            +SS  E K + ++ + +  F   Y  T   RIYP G R DSSNY+P P W+ G+QMVALN
Sbjct: 490  VSSVSEDKIQDVVKKNQGKF-QDYVNTYFVRIYPLGLRFDSSNYDPFPSWSAGAQMVALN 548

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084
             QT D  M  N G F  +    ++LK             K  I+     +T+ +++I A 
Sbjct: 549  IQTKDIFMLYNYGMFLNS---SYVLK------------SKNDIQ-----MTIFIQIISAS 588

Query: 1085 HLC-----KTGRGTASPFVEVEIIG--ADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137
            ++      +  +    P+++V I G   D ++  K  T+ + DNG +P++N  C+ ++ +
Sbjct: 589  NIVWEEEKRRQQEVVDPYIKVRIAGNKEDVNNSEKWRTEVIYDNGYHPIFNYKCKIQLKH 648

Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             +  +I F      + G+ + +GQ     L LR+GYR VPL N+  + L  S ++V++ I
Sbjct: 649  AQQDVIYFQAYSYSLLGD-SLLGQYCLSPLNLRRGYRIVPLLNSQLKPLLNSFVLVNIKI 707


>UniRef50_A0CKY8 Cluster: Chromosome undetermined scaffold_20, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_20,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 773

 Score =  156 bits (379), Expect = 3e-36
 Identities = 79/183 (43%), Positives = 115/183 (62%), Gaps = 7/183 (3%)

Query: 260 EVQASQFIRDYLRDPQRDIYEPY-FTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHY 318
           E    +FIR   R    D +  +  T  +F + L+S+QNSI++  +   + DMT+PLSHY
Sbjct: 222 EADFEKFIRTAQRQQDTDYFFGFPMTADKFNDFLFSQQNSIFEMGH---SDDMTKPLSHY 278

Query: 319 WISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGTPFIYHGHTLTTKI 377
           +I+SSHNTYLT DQ + +SS+  YV  L +GCRC ELDCWD   D  P +YHG+TLT+KI
Sbjct: 279 YINSSHNTYLTKDQLAGDSSVGQYVIALLNGCRCFELDCWDSISDRNPVVYHGYTLTSKI 338

Query: 378 RFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS 437
            F D +  + +  F+ S YP+ILS+E +CS+ QQ  +    +  F D L ++  ++N + 
Sbjct: 339 LFEDAILALDKFGFMFSSYPIILSLELHCSIDQQEVLGQIMRAQFKDELYIY--EQNLSV 396

Query: 438 LPS 440
           LPS
Sbjct: 397 LPS 399



 Score =  126 bits (303), Expect = 5e-27
 Identities = 75/244 (30%), Positives = 134/244 (54%), Gaps = 7/244 (2%)

Query: 958  KGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCG 1017
            K  ++N +SS  E K +++  +++     ++    L RIYP G R+DSSN++P+P +  G
Sbjct: 532  KRSIWN-ISSLSEDKVDKIFKEKKVKEVQQHLNNYLVRIYPSGMRVDSSNFDPIPSFILG 590

Query: 1018 SQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVM 1077
            +Q++ALN+QT D+PM +N  +F QN G G++LKP+++ E      + +S +   K VT  
Sbjct: 591  AQIIALNFQTKDEPMLINRARFSQNLGIGYVLKPKYLIEGLDQVTNFESPDYPKKLVT-- 648

Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYD-SGVKLVTKTVSDNGLNPLWN---DICEF 1133
            L +I  +      +   +P V V++ G   D +G +L T  + +NGLNP ++       F
Sbjct: 649  LEIISCQLFLLHTKNVINPQVIVKLKGNKVDENGQELQTNVIYNNGLNPEFDQNYSKTTF 708

Query: 1134 EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
            EV + + A+  F V ++    +   IGQ   P   +R+G+R++PL +     +E   +  
Sbjct: 709  EVKDVDQAIFIFKVFNKSDDNKQTIIGQYALPFKNMREGFRAIPLKDENLMVMEYCYIFA 768

Query: 1194 HLSI 1197
             ++I
Sbjct: 769  QVTI 772


>UniRef50_Q4TBY5 Cluster: Chromosome undetermined SCAF7071, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7071,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1237

 Score =  156 bits (378), Expect = 4e-36
 Identities = 121/403 (30%), Positives = 193/403 (47%), Gaps = 39/403 (9%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLE----------SSKCFTIYYGTEF-KLRCASF 118
           LD+  +++ RTGK +K     P++ +  E            K  TI +G++   +   +F
Sbjct: 6   LDMSTIRDTRTGKYAKQ----PKDVRVREVLGFGKGESVERKLVTIVHGSDLVNISFLNF 61

Query: 119 VAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KA 174
            A  +   + W   +  L    +S +       +L K F  ++   N   KI +K V K 
Sbjct: 62  QAMQEDTAKIWTDELFTLATNILSQN--ASRNTFLLKAFTKLKLQVNQDGKIPVKNVLKL 119

Query: 175 FLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234
           F  K   + +  +   V    +  K  +  ++ F      L      +Q IF++      
Sbjct: 120 FSDKKRVETALEQCGLVNNRSEGLKPDDFTWEAFQNFLNSLCL-RPEIQSIFEESG--SK 176

Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSE 287
               I+L +F +F+   Q D+  ++ +       Q  Q +  Y  +  + +     +L  
Sbjct: 177 RKPFISLDQFMDFINRRQRDSRLNEVLYPPLKREQVRQIMERYESNTSQ-LERDQISLQA 235

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F   L  ++N I   +   V  DM +PLSHY+I+SSHNTYLT  Q +  SS+E Y + L 
Sbjct: 236 FARYLGGEENGIVPPERLDVIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLL 295

Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405
           +GCRC+ELDCW G   D  P+I HG T+TT+I F +V+  I E AF TS YP+ILS E++
Sbjct: 296 TGCRCVELDCWKGRPHDEEPYITHGFTMTTEIPFKEVIEAIAESAFKTSPYPVILSFENH 355

Query: 406 C-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
             S  QQ +MA   + +FGD L++ P++K        LPSP +
Sbjct: 356 VDSAKQQAKMAEYCRTIFGDALVIDPLEKYPLEPGQPLPSPQE 398



 Score =  126 bits (304), Expect = 4e-27
 Identities = 89/249 (35%), Positives = 129/249 (51%), Gaps = 47/249 (18%)

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +Y+  QLSRIYPKG R+DSSNY P  FWN G QMVALN+QT D PMQ+NMG F+ NGG G
Sbjct: 594  RYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLPMQLNMGVFEYNGGSG 653

Query: 1047 FILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGT----------- 1093
            ++LKP+FM   ++ ++P  +  ++G V   TV ++V G    C     T           
Sbjct: 654  YLLKPEFMRRTDKHFDPFTENIVDGIVAN-TVKIKV-GPSFWCPVAAPTTHQVISGQFLT 711

Query: 1094 ---ASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWND--ICEFEVANPE--------- 1139
                  +VEV++ G   D+  K  TKT + N L+P+W+D      +V  PE         
Sbjct: 712  DKKVGVYVEVDMFGLPADTKRKYRTKTSNGNSLDPVWDDDMFVFTKVGVPEPRPPRLTVP 771

Query: 1140 --------------LALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185
                          LA +R VV +E+      F+G    P+  +R G+  + L N  ++ 
Sbjct: 772  YPPSPPSPQVVLPTLASLRIVVFEEN----GKFVGHRILPVSAIRPGFHYINLKNELNQP 827

Query: 1186 LELSTLMVH 1194
            L L +L+V+
Sbjct: 828  LLLPSLLVY 836


>UniRef50_Q01970 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
            phosphodiesterase beta-3; n=27; Tetrapoda|Rep:
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            beta-3 - Homo sapiens (Human)
          Length = 1234

 Score =  156 bits (378), Expect = 4e-36
 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y   V F + E  R +   + EMSSF ETKA   +++    F V+Y+  QLS
Sbjct: 588  EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 645

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNY P  FWN G Q+VALN+QT D  MQ+N G F+ NG  G++LKP+FM
Sbjct: 646  RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 705

Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  +  ++G V    + ++VI  + L     G    +VEV++ G   D+  K
Sbjct: 706  RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 761

Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170
              T+T   N  NP+W+ +  +F +V  P LA +R    +E       F+G    P+  +R
Sbjct: 762  YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 817

Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194
             GY  V L N  ++ L L  L+++
Sbjct: 818  SGYHYVCLRNEANQPLCLPALLIY 841



 Score =  150 bits (363), Expect = 3e-34
 Identities = 123/407 (30%), Positives = 198/407 (48%), Gaps = 45/407 (11%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETK------------RLESSKCFTIYYGTE-FKLRCA 116
           LDI  +++ RTG+    + R P++ K            RLE  K  T+  G +       
Sbjct: 64  LDISSIRDTRTGR----YARLPKDPKIREVLGFGGPDARLEE-KLMTVVSGPDPVNTVFL 118

Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVK 173
           +F+A  D   + W +  L+ +A  + A    +   +LRK +  ++   N   +I +K + 
Sbjct: 119 NFMAVQDDTAKVWSEE-LFKLAMNILAQNASR-NTFLRKAYTKLKLQVNQDGRIPVKNIL 176

Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY--SV 231
                   ++ T+ L      +   +   I  D+F++   +   ++  ++   DK    +
Sbjct: 177 KMFSADKKRVETA-LESC--GLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEI 233

Query: 232 YCSNGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYF 283
                  +TL +  +F+  +Q D   ++ +       QA   I  Y  +P +   E    
Sbjct: 234 GAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQM 291

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
           ++  F   L  ++N I   +   ++ DMT+PLS Y+I+SSHNTYLT  Q +  SS+E Y 
Sbjct: 292 SMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYR 351

Query: 344 RCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           + L  GCRC+ELD W G  P+  PFI HG T+TT++   DVL  I E AF TS YP+ILS
Sbjct: 352 QALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILS 411

Query: 402 IEDNC-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443
            E++  S  QQ +MA   + +FGD LL+ P+DK   +    LPSP D
Sbjct: 412 FENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 458


>UniRef50_Q6CD33 Cluster: Similar to DEHA0A04554g Debaryomyces
           hansenii IPF 6581.1; n=1; Yarrowia lipolytica|Rep:
           Similar to DEHA0A04554g Debaryomyces hansenii IPF 6581.1
           - Yarrowia lipolytica (Candida lipolytica)
          Length = 955

 Score =  155 bits (377), Expect = 5e-36
 Identities = 106/360 (29%), Positives = 174/360 (48%), Gaps = 29/360 (8%)

Query: 100 SKCFTIYYGTEFKLRCASFVAQTDKECEAWV---KGVLYLIAEAV----SASYPLQIERW 152
           S+  TI Y    + +    VA T +E   +V   + ++Y   E +    S++  +    W
Sbjct: 291 SRWVTITYMKNKRRKPLHLVAPTKEEFTLFVDALQNLVYFRQELMRGFQSSNPKIASVHW 350

Query: 153 LRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLY 212
             K + + E   E++T + V+    + +   S + L+  F + D +K G + F++F + +
Sbjct: 351 --KSYAAKEQGEERLTFEAVQRLAQRHHVLCSKAYLKSKFDEADVDKSGFLEFNEFKI-F 407

Query: 213 QKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLR 272
            KL+       +I   Y           +       RD+    L  D VQ ++F      
Sbjct: 408 VKLL---KRRPEIVTLYYQTLGKPEPANIWSDDRMTRDDLLGFL--DHVQRTRFEPHIFE 462

Query: 273 D------PQRDIYEP---YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSS 323
                  P+ D ++    Y+T+  F + L S  N      + K   ++ RPL+ Y+IS+S
Sbjct: 463 KIWAKFAPKDDTFDSSLDYWTVDSFNDFLLSSYNL-----FVKPETNLNRPLNEYYISTS 517

Query: 324 HNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVL 383
           HNTYL G Q +  SS E Y+R L+SGCR +E+D WDGPD  P + HG T T+ +   DV 
Sbjct: 518 HNTYLIGRQVADTSSEEGYIRALQSGCRSVEIDIWDGPDDRPVVKHGRTFTSSVSVEDVC 577

Query: 384 RTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
             I+++ FI S  PLILS+E +CS   Q ++    +  FG+ L+  P+     +LPSPH+
Sbjct: 578 SAIRKYGFIASPNPLILSLEIHCSASNQLKVVDILKGTFGENLVTQPLVPGALNLPSPHE 637



 Score =  108 bits (260), Expect = 8e-22
 Identities = 84/274 (30%), Positives = 130/274 (47%), Gaps = 22/274 (8%)

Query: 931  TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTF-FVKYH 989
            T +I   + +L +Y + + F       +    N   SF E K   +    EN    +K++
Sbjct: 700  TKKIVPALGELGVYVQGLKFRNFAFP-ESKTTNHCFSFSERKFISICKDPENREQMMKHN 758

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
               L+RIYP G R+ SSN NP+ FW  G+QMVALN+QT D P Q+N   F   G  G++L
Sbjct: 759  RRYLTRIYPSGYRVKSSNLNPLYFWQNGAQMVALNWQTYDLPAQLNDAMFAARG--GYVL 816

Query: 1050 KPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK---TGRGTASPFVEVEIIGAD 1106
            KP ++          + ++      +V L  I A+ L +    G+ +  P++  ++ G  
Sbjct: 817  KPPYL----------RHLKSPRSGHSVNLSFISAQQLPRPKDLGKSSFDPYIVAQLHGPG 866

Query: 1107 YDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPL 1166
             +   KL T  V DNG NP WN      + +PE     FV     ++ +      +   L
Sbjct: 867  ENH--KLKTSPVIDNGFNPRWNKDWSLSL-SPEDYEFSFV--QITLYTQDRPFAVSCLRL 921

Query: 1167 LCLRKGYRSVPLTNAFSEELELSTLMVHLSIITD 1200
              L +GYR VPL +   EE   STL + +S I++
Sbjct: 922  SSLNEGYRHVPLNDLQGEEYLFSTLFMKVSKISN 955


>UniRef50_Q5KJZ5 Cluster: Phosphoinositide phospholipase C,
           putative; n=2; Filobasidiella neoformans|Rep:
           Phosphoinositide phospholipase C, putative -
           Cryptococcus neoformans (Filobasidiella neoformans)
          Length = 604

 Score =  153 bits (372), Expect = 2e-35
 Identities = 67/135 (49%), Positives = 95/135 (70%), Gaps = 1/135 (0%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
           QDMT PL HY+ISSSHNTYL G+Q+  ES++E Y+R L +GCRC+E+D   G D  P +Y
Sbjct: 158 QDMTHPLQHYFISSSHNTYLVGEQWKGESTVEGYIRVLLAGCRCVEMDVQSG-DVEPVVY 216

Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
           H  TLT+ +   D+ R IK++ F+TS YP+I+S E +C+  QQ R+A   ++VFGD+L+ 
Sbjct: 217 HRKTLTSSVPVRDICRAIKQYGFVTSPYPIIISTEIHCASEQQNRLAIILKEVFGDMLVS 276

Query: 429 HPMDKNETSLPSPHD 443
            P+ +  + LPSP D
Sbjct: 277 APLVEEFSELPSPED 291



 Score = 93.5 bits (222), Expect = 3e-17
 Identities = 72/273 (26%), Positives = 134/273 (49%), Gaps = 28/273 (10%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            K ER    + ++S+L++Y   V +     ++  ++ +   S  E  A +++ + +   ++
Sbjct: 343  KTERPDIFSPQLSELLVYTHGVKYQ-GFSKLNEYLPSHQFSVSERTAAKILKENK-VDWI 400

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            K++   +SR+YP+G R+ S+N+NPV  W+ G Q+VALN+QT D+ + +N   F  +   G
Sbjct: 401  KHNFKHISRVYPRGTRLGSTNFNPVDSWSAGCQIVALNWQTLDESILLNHAMFHDSN--G 458

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR-HLCKTGRGTASPFVEVEIIGA 1105
            +ILKP  + E        K +E   K +  +  + G R  LC      A  +VE  + G 
Sbjct: 459  YILKPLSLRE--------KVVEVPEKYLLTVRIISGQRTPLC------ADLYVEAILNGK 504

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEV-ANPELALIRFVVQDEDIFGEPNFIGQATF 1164
                 +   T+ +S   LNPLW++   FE+ + P L ++ F+  +           Q   
Sbjct: 505  -----ISKRTRALSQVTLNPLWDETLTFEITSTPSLLMLNFLHLE---VRNKALQAQWMR 556

Query: 1165 PLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            P+    +GY  +PL ++       +TL V +++
Sbjct: 557  PVSLAPRGYHHLPLYDSLLSRFVFATLFVKITV 589


>UniRef50_Q4PA81 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 1491

 Score =  153 bits (371), Expect = 3e-35
 Identities = 71/140 (50%), Positives = 92/140 (65%), Gaps = 5/140 (3%)

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           +  DMTRPLS Y+ISSSHNTYL G Q+  +S++E Y+R L  G R +ELDCWDGP+  P 
Sbjct: 720 IQHDMTRPLSEYYISSSHNTYLVGGQWKGDSTVEGYIRALLQGARSVELDCWDGPNNVPQ 779

Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426
           I HG TLT+++ F DV+  I  +AF+TS YPLILS+E +   PQQ  MA    D  G++L
Sbjct: 780 ITHGRTLTSRVPFQDVISAIARYAFVTSPYPLILSLEVHADPPQQEVMARILIDTLGEML 839

Query: 427 LVHPMDK-----NETSLPSP 441
           L  P+D      +   LPSP
Sbjct: 840 LSQPIDSQTLPGSTDELPSP 859



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 9/143 (6%)

Query: 958  KGFVYNEMSSFPETKAERLMSQQ-ENTFFVKYHTTQLSRIYPKGQ---RIDSS-NYNPVP 1012
            + +    M S  E  A +++     N   +K++ + L+RIYP      R+ +S N+ P+ 
Sbjct: 1012 ESYATQHMVSLSEKTALKMIRDPISNEALIKHNRSHLTRIYPSMMSFARLHASRNFVPLD 1071

Query: 1013 FWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVK 1072
             W  G Q+VALN+QT D   ++N   F +NG CG++LKP  +  + +     K+++GKV 
Sbjct: 1072 MWAAGCQLVALNWQTTDLGFELNQAMFSRNGRCGYVLKPAALRTKEHG----KTLQGKVV 1127

Query: 1073 PVTVMLRVIGARHLCKTGRGTAS 1095
               + LR++ A+ L K  +  AS
Sbjct: 1128 RFQLDLRIVSAQQLPKKNKAGAS 1150



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 49/210 (23%), Positives = 91/210 (43%), Gaps = 13/210 (6%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           +++  ++EVR G S+  + R          S+  TI Y      +    +A +D+    W
Sbjct: 324 VNLESIREVRFGPSAASY-RTSLNISSAHESRWLTIIYQNNGIYKALHLIALSDQSLSRW 382

Query: 130 VKGVLYL------IAEAVSASYPLQIER--WLRKEFYSIENSH-EKITLKEVKAFLPKIN 180
              +L+L      +  AV AS  L+  R  W+R  +   + S+ EK++++EV     ++ 
Sbjct: 383 RASLLHLQSLRRELLGAVGASSSLENRRHLWMRHHWKDADESNDEKLSIEEVILLCRRLG 442

Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240
            + + + LR  F   D   RG + F DF   +  L+    +++ IF  ++          
Sbjct: 443 IESNKAHLRRCFNLADWRNRGFLDFQDFQ-HFVSLLKQRADIETIFAAWADQPLEQPLEQ 501

Query: 241 LREFQNFLRDEQHDNLGD-DEVQASQFIRD 269
           LR      +D+ HD  G   E++ S  + D
Sbjct: 502 LRRGSGVTKDD-HDLRGQAPELEGSPALSD 530


>UniRef50_O97033 Cluster: PLC-betaS; n=1; Ephydatia fluviatilis|Rep:
           PLC-betaS - Ephydatia fluviatilis
          Length = 1355

 Score =  151 bits (366), Expect = 1e-34
 Identities = 130/398 (32%), Positives = 190/398 (47%), Gaps = 31/398 (7%)

Query: 71  DIRDVKEVRTGK----SSK--DFERWPEETKRLESSKCFTIYYGTE--FKLRCASFVAQT 122
           D+  + +VR GK     SK  +F R    +  LE  +  T+ Y  E    L     +A +
Sbjct: 64  DVTHISDVRAGKVPYKDSKLHEFLRSMTSSDYLEPEQFLTMVYRREGIVNLDHVQLMAPS 123

Query: 123 DKECEAWVKGVLYLIAEAV--SASYPLQIERWLRKEFYSIENSHEKITLKEV-KAFLPKI 179
               E W + V  ++   +  +AS     +R  ++   S  N + +I +K + +A L ++
Sbjct: 124 MDVAEKWKRAVNAIVFNMLRFNASTLTFFKRNYQRILLSC-NGYGQIPVKSICRALLLRV 182

Query: 180 NCKISTSKLRDVFQ------DVDTEKRGEIGF--DDFAVLYQKLIFDENNVQDIFDKYSV 231
             K +  +L  +F       D  TE   +  F  D +  L  +L     +  +   K   
Sbjct: 183 RDK-TDMELFGIFDAQKKKMDDGTEYIQDTDFTWDKYEQLVNQLTKGRTSDMECVIKDLG 241

Query: 232 YCSNGTTITLREFQNFLRDEQHD---NLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEF 288
                  +TL+EF NFL   Q D   N         Q  ++     +    E   T    
Sbjct: 242 KSKKHQQLTLQEFHNFLTKCQRDPRLNTILYPPPTKQQAKELAEKYEGKAVEDRLTPRAL 301

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
           +  L S+ N++   +      DMT+PLSHY+I+SSHNTYLTG Q  S S++E Y +CL  
Sbjct: 302 LNFLMSEDNNVLGVENLDQFMDMTQPLSHYFINSSHNTYLTGHQLRSLSTVEMYRQCLLL 361

Query: 349 GCRCIELDCWDGPDGTPFIY-HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407
           GCRC+ELD W  P+G   I  HG TL TKI F DV+  I E+AFITSE+P+ILSIE++C 
Sbjct: 362 GCRCVELDLW--PEGEDIIITHGGTLCTKIPFKDVVEAISEYAFITSEFPVILSIENHCR 419

Query: 408 LPQQ--RRMASAFQDVFGDLLLVHPMDKN--ETSLPSP 441
                 +++AS F  VFGD L   P+D    E  LP P
Sbjct: 420 HKPLLIQKIASTFALVFGDKLQKSPLDDYPLEPGLPLP 457



 Score =  149 bits (360), Expect = 6e-34
 Identities = 94/265 (35%), Positives = 143/265 (53%), Gaps = 17/265 (6%)

Query: 940  DLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPK 999
            D+I YC  +TF       K       SSF E K   L+      F VKY+  Q+SRIYP+
Sbjct: 767  DIINYCSGITFEGFEAAEKTNCSFYQSSFNEDKGVSLVKVTAREF-VKYNMRQMSRIYPQ 825

Query: 1000 GQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG- 1058
            G RI+SSNY P  FWN G Q+VALN+Q+ D P+Q+N  K++ NG  G++LKP    +E  
Sbjct: 826  GGRINSSNYMPQIFWNVGCQLVALNFQSTDLPIQLNNAKYEFNGVTGYLLKPAAYLKERT 885

Query: 1059 ----YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLV 1114
                +NP  +  +E  + P T+ L+VI    L  T + T +  VE ++ G   D+ V   
Sbjct: 886  TGGLFNPFIQNPVE-NIVPATLTLKVISGIFL--TEKRT-NCLVEAQMFGLPSDT-VNHK 940

Query: 1115 TKTVSDNGLNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172
              T      +P+W+       ++  PE+A++R  V DED       +GQ + P+  +R G
Sbjct: 941  FYTTKKEAPHPVWDHEPFTFAKILLPEMAMLRVAVYDED----RELLGQRSLPVNAIRAG 996

Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197
            YR +PL + +++ L L++L VH+ +
Sbjct: 997  YRHIPLRDKYNQPLSLASLFVHIMV 1021


>UniRef50_Q75C92 Cluster: ACR024Wp; n=1; Eremothecium gossypii|Rep:
           ACR024Wp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 877

 Score =  151 bits (366), Expect = 1e-34
 Identities = 103/369 (27%), Positives = 184/369 (49%), Gaps = 32/369 (8%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           L++  +K++R  + +K++    +      S     IY  +  KL+    +A T  EC  +
Sbjct: 166 LELDTIKDIRMAEMAKNYREQYDIMDAFASRWITIIYQVSPTKLKALHLIAPTQLECAKF 225

Query: 130 VKGVLYL------IAEAVS--ASYPLQIERW-LRKEFYSIENSHEKITLKEVKAFLPKIN 180
              VL +      + E++S  +S       W +       + S + ++ ++V+    K +
Sbjct: 226 YNAVLTVARQRRELMESISVPSSEAFANIHWKVNVSSKKADESRDTLSFEDVQRLCTKFH 285

Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240
              S++ L+ VF+  D  + G + F +F   + +++   + V +I+ K +   +    I 
Sbjct: 286 IYCSSNYLKRVFKIADVNRNGLLNFSEFCT-FVRMLKKRHEVTEIWQKIA---AETRAID 341

Query: 241 LREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEML-YSKQNSI 299
             +F +FL D Q +++       +Q  RD   +   + Y     L +F+    Y+++   
Sbjct: 342 FEKFYSFLTDVQCEDMD------AQLARDLFNEYSHEGYMDEDLLLKFLTAQPYARE--- 392

Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359
                  + +D +RPLS Y+ISSSHNTYL G+Q  S +S+E Y++ L+ GCR +E+D WD
Sbjct: 393 -------IEEDYSRPLSEYFISSSHNTYLLGNQVGSMASVEGYIQALQQGCRSVEIDIWD 445

Query: 360 GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQ 419
             DG P + HG  LT+ +   +V+  I ++AFITS YPLILS+E +C    Q  +   F 
Sbjct: 446 SDDG-PVVCHG-KLTSSLPLRNVVDVINKYAFITSPYPLILSLEIHCRSEGQIIVKQLFD 503

Query: 420 DVFGDLLLV 428
           D+ G L+ V
Sbjct: 504 DILGPLIYV 512



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 63/232 (27%), Positives = 102/232 (43%), Gaps = 30/232 (12%)

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNG--- 1043
            K++   L R+YP   R  SSNY+P+  W  G QMVA N+QT D   Q+N   F+      
Sbjct: 640  KHNRRHLMRVYPHAFRYKSSNYDPIKCWRLGVQMVATNWQTYDLGQQLNQAMFRVTARDD 699

Query: 1044 ---GCGFILKPQFMFEEGYNPCDKKSIEGKV--KPVTVMLRVIGARHLCK------TGRG 1092
                 G++ KP+++          + I   V    V + L ++ A+ L K       G  
Sbjct: 700  WPWPSGYVRKPEYLLHTVPKTSFIRDIYEAVHSSVVALSLELLSAQLLPKPKLSSRDGEA 759

Query: 1093 TASPFVEVEIIG------ADYDSGVKLVTKTVS-----DNGLNPLWNDICEFEVANPELA 1141
              +P+V +E++G          +G+      V+     +NG NP+W       + N    
Sbjct: 760  HFAPYVVIEVLGDGLCGPIHVQNGLVTAPNQVTSCRCPENGFNPVWKTSLTATLNNTGFN 819

Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
             IR++V++ DI      +      L  +++GYR +PL +  S     STL V
Sbjct: 820  FIRYIVKNADI-----TLATCCIRLDYMKRGYRHIPLYSLESSRFIFSTLFV 866


>UniRef50_Q00722 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-2; n=18; Euteleostomi|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-2 - Homo sapiens (Human)
          Length = 1181

 Score =  151 bits (366), Expect = 1e-34
 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%)

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
           V  L   +NS+       +  DMT+PL+HY+I+SSHNTYLT  QFS  SS E Y + L S
Sbjct: 292 VWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 351

Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
           GCRC+ELDCW G  PD  P I HG T+TT I F + +  I E AF TS YP+ILS E++ 
Sbjct: 352 GCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHV 411

Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443
             P QQ +MA   + +FGD+LL  P++    K    LPSP D
Sbjct: 412 DSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPED 453



 Score =  144 bits (350), Expect = 1e-32
 Identities = 100/270 (37%), Positives = 146/270 (54%), Gaps = 20/270 (7%)

Query: 936  KEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +E+S L+ Y +    V+F     + + +V   +SSF E KA  L+S+  +  FV Y+  Q
Sbjct: 540  EEMSSLVNYIQPTKFVSFEFSAQKNRSYV---ISSFTELKAYDLLSKA-SVQFVDYNKRQ 595

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            +SRIYPKG R+DSSNY P  FWN G QMVALN+QT D PMQ NM  F+ NG  G++LK +
Sbjct: 596  MSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHE 655

Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110
            FM   ++ +NP     I+  V   T+ + VI  + L +    T   +VEVE+ G   D  
Sbjct: 656  FMRRPDKQFNPFSVDRID-VVVATTLSITVISGQFLSERSVRT---YVEVELFGLPGDPK 711

Query: 1111 VKLVTK-TVSDNGLNPLW-NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167
             +  TK + S N +NP+W  +   FE +  PELA +R  V +E       F+G    P+ 
Sbjct: 712  RRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEG----NKFLGHRIIPIN 767

Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
             L  GY  + L +  +  L +  L + L +
Sbjct: 768  ALNSGYHHLCLHSESNMPLTMPALFIFLEM 797


>UniRef50_Q6FY00 Cluster: Similar to sp|P32383 Saccharomyces
           cerevisiae YPL268w PLC1 1- phosphatidylinositol-4; n=1;
           Candida glabrata|Rep: Similar to sp|P32383 Saccharomyces
           cerevisiae YPL268w PLC1 1- phosphatidylinositol-4 -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 850

 Score =  150 bits (363), Expect = 3e-34
 Identities = 108/381 (28%), Positives = 177/381 (46%), Gaps = 32/381 (8%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129
           L++  +K +R G+   ++ R         S    TI Y    KL+    +A+ + +   +
Sbjct: 149 LNLDSIKSIRPGELGSNY-REEYNVDASYSKYWVTIIYKVSNKLKALHVIARDESDYNVF 207

Query: 130 VKGVLYLIAEAVSASYPLQIE--------RWLRKEFYSI-ENSHEKITLKEVKAFLPKIN 180
              V  L+         L +          W R    +  E + E +  ++V+    + +
Sbjct: 208 CSLVFGLVRTRRELMESLAVPDHDKFADIHWNRALSRNPDEKAEEVLGFEDVRQMCQRFH 267

Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240
              S   LR  F   DT   G + F++F V + KL+     + D++ +      +   +T
Sbjct: 268 IYCSAGYLRRFFDAADTNNSGTLSFEEFQV-FVKLLKARKEIDDVWQE--AVGLHEDKLT 324

Query: 241 LREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIY 300
              F  FL + Q + + +DE               R +YE Y T    +     ++    
Sbjct: 325 FDTFYKFLTEIQRERMDEDEA--------------RHLYERYETAGGGINKQGFEKYLTT 370

Query: 301 DSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360
                   +D +RP++ Y+I+SSHNTYLTG Q     S+E Y++ L+ GCR +E+D WDG
Sbjct: 371 SPYMLPNNEDYSRPMNQYYIASSHNTYLTGKQIGGAPSVEGYIQALQQGCRSVEIDMWDG 430

Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420
            + +P + HG  LT+ +    V + I+++AFITS YPLI+S+E  C+   QR  AS F+D
Sbjct: 431 -ESSPVVCHG-VLTSALPLSSVTQIIRKYAFITSPYPLIISMEVRCNSKNQRIAASIFKD 488

Query: 421 VFGDLLLVHPMDKNETSLPSP 441
            FGDLL     D++E  LPSP
Sbjct: 489 TFGDLLYTCE-DRSE--LPSP 506



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 68/255 (26%), Positives = 108/255 (42%), Gaps = 33/255 (12%)

Query: 967  SFPETKAERLMSQQENTFFV-KYHTTQLSRIYPKGQRIDSSNY-NPVPFWNCGSQMVALN 1024
            S  E + ++++   +    V K++   + R+YP   R  S+N+ +PV FW  G QMVA N
Sbjct: 603  SLDERRLDKMLGDAQVAAAVDKHNRRHMMRVYPHALRYRSTNFEDPVRFWRLGVQMVATN 662

Query: 1025 YQTPDKPMQVNMGKF------KQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVML 1078
            +QT D   Q+N+  F      +Q    G++LKP ++      P  K+  E     + V  
Sbjct: 663  WQTNDVGHQLNVAMFQLNTRNQQQMPSGYVLKPGWL----ARPPSKRRRERCGAVLRVTF 718

Query: 1079 RVIGARHLCKTGRGTASPFVEVEIIGAD-YDSGVKLVT-------KTVS------DNGLN 1124
             VI A+ L      T +      I  A+  D     VT        TV       +NG +
Sbjct: 719  EVISAQLLPNLSESTETKSQAASIGAAETEDPYYTQVTCEMFSCGSTVEKSSKCHENGFS 778

Query: 1125 PLWNDICEFEVANPE--LALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAF 1182
            P+W      +V   E     +R VV+  +       +      +  LR+GYR +PL +  
Sbjct: 779  PVWRSALSQDVRRDEYPFVFVRVVVRRCE-----EVVATTCVRVCQLREGYRHIPLCSPD 833

Query: 1183 SEELELSTLMVHLSI 1197
             E+   STL V   +
Sbjct: 834  GEQYVFSTLFVRYRV 848


>UniRef50_A3KGF7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-2; n=15; Eutheria|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase beta-2 - Mus musculus (Mouse)
          Length = 1181

 Score =  149 bits (362), Expect = 3e-34
 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%)

Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348
           V  L   +NS+       + QDMT+PL+HY+I+SSHNTYLT  QFS  SS E Y + L S
Sbjct: 292 VWFLCGPENSVLAHDTLLIHQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 351

Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406
           GCRC+ELDCW G  PD  P I HG T+TT I F + +  I E AF TS YP+ILS E++ 
Sbjct: 352 GCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHV 411

Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443
             P QQ +MA   + +FG+ LL  P++    K    LPSP D
Sbjct: 412 DSPRQQAKMAEYCRSMFGETLLTDPLENFPLKPGIPLPSPED 453



 Score =  145 bits (351), Expect = 7e-33
 Identities = 99/269 (36%), Positives = 144/269 (53%), Gaps = 18/269 (6%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S L+ Y +   F + E    K   Y  +SSF E KA  L+S+    F V Y+  Q+S
Sbjct: 545  EEMSSLVNYIQPTKFISFEFSAQKNRSY-VVSSFTELKAYELLSKASMQF-VDYNKRQMS 602

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            R+YPKG R+DSSNY P  FWN G QMVALN+QT D PMQ NM  F+ NG  G++LK +FM
Sbjct: 603  RVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFM 662

Query: 1055 --FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ +NP     I+  V   T+ + +I  + L +    T   +VEVE+ G   D   +
Sbjct: 663  RRLDKQFNPFSVDRID-VVVATTLSITIISGQFLSERSVRT---YVEVELFGLPGDPKRR 718

Query: 1113 LVTK-TVSDNGLNPLWND---ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168
              TK + + N +NP+W +   I E ++  PELA +R  V +E       F+G    P+  
Sbjct: 719  YRTKLSPTANSINPVWKEEPFIFE-KILMPELASLRIAVMEEG----SKFLGHRIIPINA 773

Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L  GY  + L +  +  L +  L V L +
Sbjct: 774  LHSGYHHLCLRSESNMALTMPALFVFLEM 802


>UniRef50_UPI00015A791C Cluster: UPI00015A791C related cluster; n=1;
            Danio rerio|Rep: UPI00015A791C UniRef100 entry - Danio
            rerio
          Length = 658

 Score =  149 bits (361), Expect = 5e-34
 Identities = 87/217 (40%), Positives = 128/217 (58%), Gaps = 13/217 (5%)

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047
            Y+  Q+SRIYPKG R+DSSNY P  FWN G QMV+LN+QTPD  MQ+N GKF+ NG CG+
Sbjct: 271  YNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLGMQLNQGKFEYNGACGY 330

Query: 1048 ILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGA 1105
            +LKP FM   +  ++P  +  ++G V   T  ++V   + L     GT   +VEV++ G 
Sbjct: 331  LLKPDFMRRGDRMFDPFSETPVDG-VIAATCSVQVFSGQFLSDKKIGT---YVEVDMYGL 386

Query: 1106 DYDSGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162
              D+  K   T+ V +NGLNP +N+      ++  P+LA++R  V D++       IGQ 
Sbjct: 387  PTDTIRKEFRTRMVMNNGLNPYYNEEPFVFRKLILPDLAVLRIAVFDDN----SKLIGQR 442

Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199
              PL  L+ GYR + L N  ++ L L T+  ++ + T
Sbjct: 443  LLPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKT 479



 Score = 93.1 bits (221), Expect = 4e-17
 Identities = 48/99 (48%), Positives = 62/99 (62%), Gaps = 4/99 (4%)

Query: 288 FVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346
           F   L S +N+ ++  + D + Q+M  PLSHY+ISSSHNTYLTG QF  +SS+E Y + L
Sbjct: 8   FCRYLMSDENAPVFLDRLD-LCQEMEHPLSHYFISSSHNTYLTGRQFGGKSSVEMYRQVL 66

Query: 347 RSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVL 383
            SGC   ELDCWD  G D  P I HG  + T I F  ++
Sbjct: 67  LSGCYTKELDCWDGKGEDQEPIITHGKAMCTDILFKQII 105


>UniRef50_P32383 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1; n=2; Saccharomyces cerevisiae|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 869

 Score =  148 bits (359), Expect = 8e-34
 Identities = 116/386 (30%), Positives = 195/386 (50%), Gaps = 33/386 (8%)

Query: 70  LDIRDVKEVRTGKSSKDFERWPEETKRLES-SKCF-TIYYGTEFKLRCASFVAQTDKECE 127
           L++  VK++R G ++  ++    + KRL S SK +  I Y    KL+    VA  + +  
Sbjct: 146 LELDSVKDIRIGDTASTYQE-EVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFN 204

Query: 128 AWVKGVLYLIA------EAVSASYPLQIERWLRKEFYSIENSHEK---ITLKEVKAFLPK 178
            ++  +  L+       E++      Q  R   +   S +   EK   ++  +VK    K
Sbjct: 205 TFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDK 264

Query: 179 INCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238
            +  +ST +L + FQ  D    G + + +F   + K++ +   V  I+ K++      + 
Sbjct: 265 FHIYVSTGQLLEFFQLADINHNGLLNYFEFEK-FIKILKNRKEVNMIWSKFTK--PPHSH 321

Query: 239 ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFV-EMLYSKQN 297
           ++   F  FL  EQH+ + D +   S FI+ Y    Q  + +  FT  +F+ E  Y  + 
Sbjct: 322 LSFENFFQFLITEQHEQV-DRQTAWSYFIK-YREPTQLTMGQDGFT--KFLKEQPYLVE- 376

Query: 298 SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDC 357
            + +  Y K       PL+HY+I+SSHNTYL G Q +   S+E Y++ L+ GCRC+E+D 
Sbjct: 377 -VKEELYSK-------PLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDI 428

Query: 358 WDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASA 417
           WDG +G P + HG  LT+ I    V+R IK++AFITS YPLI+S+E NC+   Q+  +  
Sbjct: 429 WDGENG-PVVCHGF-LTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLI 486

Query: 418 FQDVFGDLLLVHPMDKNETSLPSPHD 443
            ++V  + L  + +      LPSP +
Sbjct: 487 MREVLAEQL--YFVGTRTDKLPSPRE 510



 Score =  102 bits (244), Expect = 7e-20
 Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 34/261 (13%)

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025
            S  E K E ++  +     +  H  + L R+YP   R  SSN+NP+PFW  G QMVA N+
Sbjct: 614  SLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNW 673

Query: 1026 QTPDKPMQVNMGKFK----QNGG---CGFILKPQFMF----EEGYNPCDKKSIEGKVKPV 1074
            QT D   Q+N+  F+    Q  G    G++LKP+ +     +    P   +  E    PV
Sbjct: 674  QTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPV 733

Query: 1075 TVMLRVIGARHL-----CKTGRGTASPFVEVEIIGAD-------YDSGVKL-----VTKT 1117
            TV +R++  + L         R   + FV+VE    D        D G ++      TK+
Sbjct: 734  TVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKS 793

Query: 1118 VSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVP 1177
               NG NP+W+      + + +L  I+F+V       E   I      L  LR GYR +P
Sbjct: 794  SQGNGFNPIWDAEVSITLKDTDLTFIKFMV-----ISEETQIASVCLKLNYLRMGYRHIP 848

Query: 1178 LTNAFSEELELSTLMVHLSII 1198
            L N   E+    TL +H  I+
Sbjct: 849  LFNMEGEQYIFCTLFIHTQIL 869


>UniRef50_A7TR21 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 873

 Score =  147 bits (357), Expect = 1e-33
 Identities = 111/384 (28%), Positives = 186/384 (48%), Gaps = 33/384 (8%)

Query: 67  EGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKEC 126
           E +L+I  +K++R    + ++ +         S+   T+ +    KL+    +A    + 
Sbjct: 146 EKSLEIDSIKDIRVDTLAINYRK-EYNIPDSSSNLWITVIFEVSKKLKALHLIANKHTDF 204

Query: 127 EAW---VKGVL-YLIAEAVSASYPLQIERWLRKEFYSI------ENSHEKITLKEVKAFL 176
           + +   + G++ Y      S S P + E++    ++S       + S + ++  ++K   
Sbjct: 205 QTFCTCIGGLVKYRYDLMKSVSVP-ESEKFANIHWHSSVSEKKEDESKDTLSFVDIKRLC 263

Query: 177 PKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNG 236
            K +   S+  L   F   D    G + F +F    Q L        +I   +    +  
Sbjct: 264 DKFHIYCSSKHLLKFFTAADINHNGLLNFKEFQTFVQLL----KRRDEIIKVWESLTNCR 319

Query: 237 TTITLREFQNFLRDEQHDNLGDDEVQASQF-IRDYLRDPQRDIYEPYFTLSEFVEMLYSK 295
             + L EF  F+   Q +     E +AS F I +  + P +     Y  L+ F+  L S 
Sbjct: 320 QYLNLDEFHEFVTKIQKEK----EDKASIFTIYNKFKSPDKK----YMDLNGFINYL-SS 370

Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355
           Q  I D   D V  D ++PL+HY+I+SSHNTYL G QF    S+E Y++ L+ GCRC+E+
Sbjct: 371 QPYIND---DVV--DYSKPLNHYYIASSHNTYLLGKQFGETPSVEGYIQVLQQGCRCVEI 425

Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415
           D WD  +G P + H   LT+ I  +DV   I+++AFITS YPLI+S+E NC+   Q +  
Sbjct: 426 DIWDDENG-PVVCHSF-LTSSIPLLDVASVIRKYAFITSPYPLIISLETNCNKINQLKAV 483

Query: 416 SAFQDVFGDLLLVHPMDKNETSLP 439
           S F+D+FGD L  + +D +  + P
Sbjct: 484 SIFKDIFGDSLCTNILDGDALASP 507



 Score = 95.9 bits (228), Expect = 6e-18
 Identities = 79/254 (31%), Positives = 112/254 (44%), Gaps = 31/254 (12%)

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025
            S  E K E L         V  H  + L RIYP   R  SSN++P+  W  G+QMVA N+
Sbjct: 622  SLNEKKLEHLCKDTTQKLAVDKHNRRFLMRIYPHALRYKSSNFDPIKCWEIGTQMVATNW 681

Query: 1026 QTPDKPMQVNMGKFKQNG------GCGFILKPQFMFEEGYNPCDKKSI--EGKVKPVTVM 1077
            QT D   Q+N+  FK           G+ LKP  +  E     D   +  E K  PVTV 
Sbjct: 682  QTNDLGHQLNLALFKLTDQKQELLHTGYALKPPKLLPEVTKSRDLTQLYKETKKDPVTVC 741

Query: 1078 LRVIGARHL-----CKTGRGTASPFVEVEII-------GADYDSGVKLVTKTVS-----D 1120
            + ++  + L      K+   T +P+V  E I             G  L  K  S     +
Sbjct: 742  ITLLSGQLLPKPKNIKSNEDTFAPYVVTEFICNCEPVKPLMVKFGTALSPKVCSTPRCKE 801

Query: 1121 NGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180
            NG +P WN      + + ELA ++F V+ E+     + +   T  L  +RKGYR +PL N
Sbjct: 802  NGFSPTWNTEMCITLKDIELAFVKFTVKTEE-----SILASCTLKLDYIRKGYRHIPLYN 856

Query: 1181 AFSEELELSTLMVH 1194
               E+   STL ++
Sbjct: 857  PKGEKYIFSTLFIN 870


>UniRef50_O13433 Cluster: 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1; n=3; Candida|Rep:
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase 1 - Candida albicans (Yeast)
          Length = 1099

 Score =  140 bits (339), Expect = 2e-31
 Identities = 95/320 (29%), Positives = 162/320 (50%), Gaps = 51/320 (15%)

Query: 159 SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV------DTEK-------RGEIGF 205
           S ++  E ++  ++  +  ++N  ++T+ L+ +F  V       TEK          + F
Sbjct: 409 SHKHVREFLSFNDILKYSKRLNINVNTNHLQQIFDQVLLLSSATTEKPVSTPLFEKGLNF 468

Query: 206 DDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQ 265
           + F   +  ++ D  ++Q+I+D  +        +   E +NF+ + Q +N  DD+  ++ 
Sbjct: 469 EQFKQ-FVSILKDRKDLQEIWDSLA---QGKEVLQFDEIKNFIINIQKENFSDDDDNSTI 524

Query: 266 FIRDYLRDPQRDIYEPYFTLSEF--VEMLYSKQNSIYDSQYDKVTQDMTR----PLSHYW 319
            +          I++ Y +       E L     S Y + Y ++TQ  T     PL+ Y+
Sbjct: 525 NL----------IFQKYCSNDNGWNKESLNEYLLSSYSTPYREITQTQTNYYDYPLNEYF 574

Query: 320 ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT--------------- 364
           ISSSHNTYLTG Q + +SS+E Y+R L+ GCRC+E+D W+G   T               
Sbjct: 575 ISSSHNTYLTGRQVAGDSSVEGYIRTLQRGCRCVEIDIWNGDSNTTTTTVIGTKDDDDKN 634

Query: 365 ---PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDV 421
              P + HG T T  I F +V+R IK+ AFI S +PLILS+E +CS   Q ++ +  +D+
Sbjct: 635 EYEPIVNHGRTFTKPISFANVIRAIKKFAFIVSPWPLILSLEIHCSPECQIKVVNILKDI 694

Query: 422 FGDLLLVHPMDKNETSLPSP 441
            G+ +++ P+D +   LPSP
Sbjct: 695 LGENMIIAPIDIDSVILPSP 714



 Score = 90.2 bits (214), Expect = 3e-16
 Identities = 79/303 (26%), Positives = 131/303 (43%), Gaps = 36/303 (11%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I  E+S+L IY + + F    L  +   +N   S  E    R++   +    +  H  +
Sbjct: 790  KIINELSNLGIYTQGIKFRNFSLP-ESKTFNHCFSLGEKSINRMIKDDDKKISLDKHNRR 848

Query: 993  -LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             L R+YP G R+ SSN+NP+P+W+ G QMVA N+QT D   Q+N   F+     G++LKP
Sbjct: 849  YLMRVYPSGTRLKSSNFNPLPYWSHGVQMVATNWQTYDLGQQLNEALFENKIFQGYVLKP 908

Query: 1052 QFM----FEEGYNPCDKKS--IEGKVKPVTVMLRVIGARHLCKTGRG-----TASPFVEV 1100
              +     +   +  D ++       K +     +I    L K  +        +P++  
Sbjct: 909  SVLRKPTLKSSSSNVDTRTSLTTTNSKTIRFNFEIISGHQLPKFPKDDYKDQAINPYISF 968

Query: 1101 EIIGA---DYD-------------SGVKLVTKTVSDNGLNPLWNDICEFEV--ANPELAL 1142
            EIIGA    +D             S     TK + +NG NP +N      +     +L  
Sbjct: 969  EIIGAQDVQWDNNDSSPIAPTTSSSPFIRTTKIIRENGFNPNFNTKFSGSIITTTNDLIF 1028

Query: 1143 IRFVVQDEDIFGEPNF-----IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            I+FVV        P++     I      L  L++GYR + L +   E+L  S++ + +  
Sbjct: 1029 IKFVVYASTSLNYPDYGENFPIAILVTKLNYLKQGYRYIYLNDLLGEQLVYSSIFIKIEY 1088

Query: 1198 ITD 1200
              D
Sbjct: 1089 DED 1091


>UniRef50_UPI00015551EC Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein, partial - Ornithorhynchus anatinus
          Length = 650

 Score =  135 bits (326), Expect = 8e-30
 Identities = 122/488 (25%), Positives = 205/488 (42%), Gaps = 31/488 (6%)

Query: 5   CFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQR 63
           CF+    ++ I  A   IS+++ G  + K  P  R   R   +  +   + W     P +
Sbjct: 15  CFSSMPSEKKISSAGDCISFMQAGCELKKVRPNSRLYNRFFTLDGDLQALRWE----PSK 70

Query: 64  QGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQT 122
           +  + A LDI  ++E+R GK+++ F R      +L      +I +G +++      VA++
Sbjct: 71  KDPDKARLDISAIREIRPGKNTETF-RHNGLADQLCEDCALSILHGDDYE--SLDLVARS 127

Query: 123 DKECEAWVKGVLYLIAEAVSASYPLQIER------WLRKEFYSIENSHEKITLKEVKA-F 175
                 WV G+ YL++       P    R      WLR  F   +     I  +E     
Sbjct: 128 ADVANIWVSGLRYLVSRLRQGPDPPGAGREPPRLAWLRSVFEEADEEGNGILPEEAAVRL 187

Query: 176 LPKINCKISTSKLRDVFQDVDTEKRG---EIGFDDFAVLYQKLIFDENNVQDIFDKYSVY 232
           + ++   +  +++R  F+++   K      +  ++F  ++ +L        +++      
Sbjct: 188 IRRLAPALKEARIRLRFKEIQRSKEKLTTRVTREEFCEVFGELC----TRPEVYFLLVQI 243

Query: 233 CSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYE-PYFTLSEFVEM 291
             N   +   +   FL  EQ    G  E      +R Y  +P  +     +  +  F   
Sbjct: 244 SKNKEFVDAGDLLLFLEAEQ-GVAGASEDLCRDIVRRY--EPSEEGRRLGFLAIDGFTRY 300

Query: 292 LYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES-SLEAYVRCLRSGC 350
           L S +  ++D +  KVTQDM+RPLSHY+ISSS +     ++    +  +  Y R LR+GC
Sbjct: 301 LLSPECDLFDPEQRKVTQDMSRPLSHYYISSSRSPRWAAERRGGPADEVRGYERALRTGC 360

Query: 351 RCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQ 410
           R ++LD  DGPDG P +          R    L  I   AF  S +PLIL ++  CS+ Q
Sbjct: 361 RSVQLDVRDGPDGEPVLDGAAPAPPSFRL--ALEVIDRFAFAASAFPLILCLDHRCSVQQ 418

Query: 411 QRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQE- 469
           Q+ MA   + VFG  L        +  LPSP +            P G       V  + 
Sbjct: 419 QKVMARHLKGVFGPKLFGGRPPGPDAPLPSPEELRGRVVVEGRKLPPGWTAPEGDVPDDR 478

Query: 470 EGKDLDLR 477
           +G DL  R
Sbjct: 479 DGADLPQR 486


>UniRef50_Q0UC00 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 980

 Score =  134 bits (325), Expect = 1e-29
 Identities = 60/126 (47%), Positives = 80/126 (63%)

Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347
           F   L S  NS+   +       + RPL+ Y+ISSSHNTYL G Q + ESS EAY+  L+
Sbjct: 471 FQTFLTSSNNSVLKPKPSTGKLQLNRPLNEYFISSSHNTYLLGRQVAGESSTEAYISALQ 530

Query: 348 SGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407
            GCRCIE+DCWDG DG P + HG TLT  I F D ++ + + AF  S YPLILS+E N +
Sbjct: 531 KGCRCIEIDCWDGGDGLPVVMHGRTLTKAISFHDTIKVVNKFAFAESPYPLILSLEPNAT 590

Query: 408 LPQQRR 413
           + ++ +
Sbjct: 591 VMEESK 596



 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 41/302 (13%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMS--QQENTF 984
            K  +T  I KE+  L +Y R V F  +        +N + S  E K E L     +E   
Sbjct: 599  KKTKTSNITKELGTLGVYTRGVKFT-DFGCTDANTFNHVFSLNERKFETLTKAGSREKYL 657

Query: 985  FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK-QNG 1043
              +++   L R+YP   RI S+N++P+  W  G QMVALN+QT D   Q+N   F   + 
Sbjct: 658  LEEHNVRCLMRVYPHAFRITSTNFDPLKCWRRGVQMVALNWQTYDLGQQLNQAMFAGGDD 717

Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTA-----SPFV 1098
              G++LKP  +   G         +   K V   ++++ A+ L +  RG A     +P+V
Sbjct: 718  RTGYVLKPTTL-RRGSQTTIHGPRKAPKKEVKFTVQIMSAQQLPRP-RGLAQEANINPYV 775

Query: 1099 EVEIIGADYDSGVKLV-----------------------TKTVSDNGLNPLWNDICEFEV 1135
            E E+  A+ D G   +                       T+ V  NG NP +    + E+
Sbjct: 776  EFEMYCAE-DMGANAIGVGGQDASAPNGHSGIGNPLRKRTEIVPGNGYNPEFQGTKDIEM 834

Query: 1136 ----ANPELALIRFVVQDEDIFGEPNFIGQATF--PLLCLRKGYRSVPLTNAFSEELELS 1189
                  P L  +R+ V         N+   A+F   L  L++GYR +PL ++  E+   S
Sbjct: 835  KVTTRFPSLVFVRWTVWHSLDAKTTNYAPLASFTAKLNSLQQGYRHLPLFDSNGEQYLFS 894

Query: 1190 TL 1191
            TL
Sbjct: 895  TL 896


>UniRef50_A5DAA1 Cluster: Putative uncharacterized protein; n=1;
           Pichia guilliermondii|Rep: Putative uncharacterized
           protein - Pichia guilliermondii (Yeast) (Candida
           guilliermondii)
          Length = 921

 Score =  134 bits (323), Expect = 2e-29
 Identities = 88/301 (29%), Positives = 161/301 (53%), Gaps = 33/301 (10%)

Query: 160 IENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT------EKRGEIGFDDFAVLYQ 213
           ++   E + L+++  +  ++N  +  + L+DVF +V T      E +G + F+ F   + 
Sbjct: 296 VKEVRELLYLEDILKYSRRLNINLDEAFLKDVFDNVITRVATSSEPKG-LSFEGFKE-FV 353

Query: 214 KLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRD 273
            +I   +++  I++      S+ +TI   +F  F+ + Q +   ++ ++   F+R   R+
Sbjct: 354 SIIKRRDDISHIWE---ACFSSLSTIDFDKFCTFMIEIQKEEHNEEHLR-KLFVRFSKRE 409

Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQF 333
            +       +T   F   L SK ++I+ + +     D   PL+ Y+ISSSHNTYL G QF
Sbjct: 410 DRL-----IWTKESFNAFLLSKYSTIFKNDFSDDYFD--HPLNDYFISSSHNTYLIGRQF 462

Query: 334 SSESSLEAYVRCLRSGCRCIELDCWDGP--DGT-----------PFIYHGHTLTTKIRFM 380
             +SS++ Y+R  + GC+C+E+D WDG   DG            P + HG + T+ I   
Sbjct: 463 VGDSSIDGYIRAFQRGCKCVEIDIWDGMSIDGDLDNNESEGIKGPIVNHGRSFTSSISLK 522

Query: 381 DVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440
           +VL T+K++AF +S +P+ILS+E +C+   Q ++    +D+ G+ L+   +D N+  LPS
Sbjct: 523 NVLLTVKKYAFSSSSWPVILSLEVHCNAENQLKIKKLLKDILGESLVTDMLD-NDCVLPS 581

Query: 441 P 441
           P
Sbjct: 582 P 582



 Score =  126 bits (304), Expect = 4e-27
 Identities = 91/277 (32%), Positives = 137/277 (49%), Gaps = 20/277 (7%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I  E+SDL IY + + F    L  +   +N   S  E     L+S +E    +  H  +
Sbjct: 643  KIVTELSDLAIYIQGIKFRNFSLP-ESKTFNHCISLSEKSFNSLLSDEEKRLSLAKHNRK 701

Query: 993  -LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
             L R+YP   RI SSN+NP+  WN G QMVA N+QT D   Q+N   F+  GG G+ LKP
Sbjct: 702  FLMRVYPSKMRIGSSNFNPITQWNYGVQMVASNWQTYDVGQQINEALFQSCGGTGYALKP 761

Query: 1052 QFMFEEGYNPCDKKSIEGKV-KP-VTVMLRVIGARHLCKT--GRGTASPFVEVEIIGA-- 1105
            + +     +P  KK     V +P +   L++I A  L K+       +PFV VE+ G   
Sbjct: 762  KSL----RSPLSKKRKPELVQRPLMRFSLKIISALQLPKSKGSNAATNPFVSVEMHGCSL 817

Query: 1106 -DYD-SGVKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDE-DIFGEPNF-- 1158
              +D    +  T  ++ NG NP+WN+   C     N +LA +R VV       G+ +   
Sbjct: 818  IQWDGESQEPSTLIIAANGFNPIWNEQFSCIMSAEN-DLAFLRIVVNSSLSATGKEDIQP 876

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195
            +G     + C++ GYR +P+ +   EEL  S L+V +
Sbjct: 877  LGIIVLRVGCIKDGYRYLPINDPLGEELVYSKLLVRI 913


>UniRef50_Q6CSI9 Cluster: Similar to sp|P32383 Saccharomyces
           cerevisiae YPL268w PLC1 1- phosphatidylinositol-4; n=1;
           Kluyveromyces lactis|Rep: Similar to sp|P32383
           Saccharomyces cerevisiae YPL268w PLC1 1-
           phosphatidylinositol-4 - Kluyveromyces lactis (Yeast)
           (Candida sphaerica)
          Length = 976

 Score =  129 bits (312), Expect = 4e-28
 Identities = 65/133 (48%), Positives = 87/133 (65%), Gaps = 5/133 (3%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368
           +D +RPL+ Y+ISSSHNTYL G Q   E S+EAY R L+ GCRCIE+D W G  G P + 
Sbjct: 400 EDYSRPLNEYFISSSHNTYLMGKQVVDEVSVEAYTRALQQGCRCIEIDIWQGDHG-PVVC 458

Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
           HG   T  I   DV++TI+++AFITS YPLI+S+E +C    Q  +    +++ GDL+ V
Sbjct: 459 HG-LFTQSIPLEDVVKTIRKYAFITSPYPLIVSLEIHCKKDYQLMITKIMKEILGDLIFV 517

Query: 429 HPMDKNETSLPSP 441
            P +   TSL SP
Sbjct: 518 IPPN---TSLLSP 527



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 45/125 (36%), Positives = 66/125 (52%), Gaps = 8/125 (6%)

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK----QN 1042
            K++   L RIYP   R  SSN+NP+ FW  G QMVA N+QT D   Q+N   F+    +N
Sbjct: 665  KHNRRHLMRIYPHMLRYKSSNFNPIRFWKEGVQMVATNWQTYDLGQQLNHAMFQVSLDRN 724

Query: 1043 G--GCGFILKPQFMFEEGYNPCDKKSIEGKVK--PVTVMLRVIGARHLCKTGRGTASPFV 1098
                 G++LKP  + +E +   D   I  ++K   + + L VI  + L        +PFV
Sbjct: 725  SIWHSGYVLKPAHLRKEIHKMKDIPVIMERLKREKIHIHLDVISGQMLSLQNCKILAPFV 784

Query: 1099 EVEII 1103
            E+E+I
Sbjct: 785  EIELI 789



 Score = 44.8 bits (101), Expect = 0.014
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 5/79 (6%)

Query: 1115 TKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174
            TK   DNG +P+WN   E  + N     +RF V++         I      L  L++GYR
Sbjct: 894  TKCFRDNGFSPVWNASFECTLTNTTFNFVRFTVKN-----STQTIATTCVRLNYLKQGYR 948

Query: 1175 SVPLTNAFSEELELSTLMV 1193
             +PL N   E+   STL +
Sbjct: 949  HLPLYNIKGEKFIFSTLFI 967


>UniRef50_Q766D4 Cluster: Phosphoinositide-specific phospholipase C;
           n=1; Physcomitrella patens|Rep:
           Phosphoinositide-specific phospholipase C -
           Physcomitrella patens (Moss)
          Length = 634

 Score =  125 bits (301), Expect = 8e-27
 Identities = 77/225 (34%), Positives = 117/225 (52%), Gaps = 10/225 (4%)

Query: 223 QDIF-DKYSVYCSNGTTITLREFQNFLRDEQHDNLG--DDEVQASQFIRDYLRDPQRD-- 277
           QD+  D +S Y  NG  +       FL+ EQ D+    DD     + IR+     +    
Sbjct: 18  QDLLGDVFSTYSENGK-LDAEGLLKFLQTEQGDSKSSLDDAKHLVELIRNERHKSKFPGF 76

Query: 278 IYEPYFTLSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSE 336
           I     +  +F   + S   N + +S    V QDMT+PLSHY+I + HN+YLTG+Q SS+
Sbjct: 77  IVSSDLSKGDFKNYVLSPDLNGVLEST---VHQDMTQPLSHYFIFTGHNSYLTGNQLSSD 133

Query: 337 SSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEY 396
           SS       L+ G R +ELD W    G   + HG+TLT+ + F   ++ IK +AF++S+Y
Sbjct: 134 SSDVPIAAALQRGVRVVELDLWPDDKGGIKVTHGNTLTSPVAFEKCIKAIKANAFVSSKY 193

Query: 397 PLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           P+++++ED+ S P Q   A    ++ G+ L   P       LPSP
Sbjct: 194 PVVITLEDHLSSPLQALAAETLTNILGEDLYYPPSSDGFKELPSP 238



 Score =  120 bits (288), Expect = 3e-25
 Identities = 83/250 (33%), Positives = 128/250 (51%), Gaps = 14/250 (5%)

Query: 953  ERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVP 1012
            +RL+++G V     S  ETK E++ +++     VK+    + R+YP G R++SSNY+P  
Sbjct: 381  DRLKVEGTVVR--ISLSETKLEKV-TEEFPELVVKFTQRNILRVYPAGNRVNSSNYDPTA 437

Query: 1013 FWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE-----GYNPCDKKSI 1067
             W  G+QMVA N Q   K +    GKF+ NGGCG+ILKP+++ E+      +NP      
Sbjct: 438  AWIHGAQMVAQNMQGYGKELWQAHGKFRGNGGCGYILKPKYLLEDLPNGKPFNPSAPGDT 497

Query: 1068 EGKVKPVTVMLRVIGARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLN 1124
            +  +K V VM  +   +   K      SP   F  + + G   D  V     +V D+   
Sbjct: 498  KMILK-VKVMTTMGWDKAFPKYHFDLFSPPDFFTRLLVTGVPAD--VAKWKTSVIDDVWE 554

Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184
            P WN+  EF +  PELAL+R  V+D D   +  F GQA  P+  ++ GYR V + +    
Sbjct: 555  PHWNEDHEFYLKCPELALLRIEVRDHDEGSQDEFEGQACLPMHEIKDGYRCVQMYDKKGS 614

Query: 1185 ELELSTLMVH 1194
             L+   ++ H
Sbjct: 615  VLKGVKMLFH 624


>UniRef50_A7PP48 Cluster: Chromosome chr8 scaffold_23, whole genome
            shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
            chr8 scaffold_23, whole genome shotgun sequence - Vitis
            vinifera (Grape)
          Length = 615

 Score =  124 bits (300), Expect = 1e-26
 Identities = 82/222 (36%), Positives = 117/222 (52%), Gaps = 13/222 (5%)

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            +++    L R++PK  R+DSSNYNP+  W  G+QMVA N Q  D+P+ +  G F+ NGGC
Sbjct: 398  IRFTQRNLLRVFPKVMRVDSSNYNPLIGWMHGAQMVAFNMQGYDRPLWLMQGMFRANGGC 457

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV---IG-ARHL--CKTGRGTASP--- 1096
            G++ KP  + + G  P DK        PV   L+V   +G   HL    T     SP   
Sbjct: 458  GYVKKPDLLLKVG--PHDKVFDPKANLPVKTTLKVKVYMGEGWHLDFHHTHFDIYSPPDF 515

Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156
            + +V I G   DS +K  TK V D+   P WN+  EF +  PELAL+R  V + D+  + 
Sbjct: 516  YTKVGIAGVPADSLMK-KTKAVEDD-WTPTWNEEFEFPLTAPELALLRIEVHEYDMSEKD 573

Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
            +F GQ   P+  LR G R+VPL N   E+     L++    +
Sbjct: 574  DFGGQTCLPVSELRTGIRAVPLHNQKGEKYNSVKLLMRFEFV 615



 Score =  111 bits (266), Expect = 1e-22
 Identities = 76/219 (34%), Positives = 112/219 (51%), Gaps = 13/219 (5%)

Query: 229 YSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQR-DIYE--PYF 283
           ++ Y   G  ++L + Q FL + Q    G+DE      Q I D L + +   I++     
Sbjct: 76  FNDYSEQGV-MSLEQLQKFLIEVQ----GEDEASMEDVQGIMDSLHEFKHLPIFQLRKGL 130

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
            L  F   L    N    S ++ V  DM  PLSHY+I + HN+YLTG+Q SS  S    +
Sbjct: 131 NLEAFFRYLCHDLNPPL-SPHNTVHHDMNAPLSHYFIYTGHNSYLTGNQLSSICSDVPVI 189

Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402
             L+ G R IELD W         + HG TLTT ++    L +IK++AF+ SEYP+I+++
Sbjct: 190 NSLQCGVRVIELDMWPNSTKDDIDVLHGRTLTTPVKLSKCLISIKKYAFVASEYPVIITL 249

Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           ED+ +   Q ++A     +FGDLL   P  +     PSP
Sbjct: 250 EDHLTPDLQAKVAEMATQIFGDLLF-SPESECLAEFPSP 287


>UniRef50_P93620 Cluster: Phosphoinositide-specific phospholipase C;
           n=2; Vigna|Rep: Phosphoinositide-specific phospholipase
           C - Vigna unguiculata (Cowpea)
          Length = 549

 Score =  124 bits (299), Expect = 1e-26
 Identities = 72/219 (32%), Positives = 120/219 (54%), Gaps = 9/219 (4%)

Query: 224 DIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYF 283
           D+   +S +    ++++      FL + Q +   D  V  S+ I   L+  +++  E  F
Sbjct: 26  DVQKAFSEFSDGASSMSAEHLLRFLAEHQGEV--DCTVSDSEQI---LQQSRKEDGETGF 80

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
            L +F   L  ++N +      +V  DM  P+SHY+I + HN+YLTG+Q SS+ S    +
Sbjct: 81  DLHDFFHFL--QENDLNVPLKSQVHHDMNAPISHYFIYTGHNSYLTGNQLSSDCSDAPII 138

Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402
           + L+ G R IELD W   +     + HG TLTT +  +  L++IKE+AF+ S+YPL++++
Sbjct: 139 KALQRGVRVIELDLWPNSNKDDIDVVHGRTLTTPVSLLRCLKSIKEYAFVKSQYPLVITL 198

Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           ED+ +   Q ++A     VFG+ LL +P   + T  PSP
Sbjct: 199 EDHLTPDLQAKVAKMATQVFGE-LLHYPQTDSLTEFPSP 236



 Score =  117 bits (282), Expect = 2e-24
 Identities = 70/201 (34%), Positives = 111/201 (55%), Gaps = 11/201 (5%)

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            V++    + R+YPKG R++SSNY P   W  G+QMVA N Q   K +    G F+ NGGC
Sbjct: 332  VRFTHNNILRVYPKGTRLNSSNYKPHIGWTYGAQMVAFNMQGHGKSLWYMQGMFRSNGGC 391

Query: 1046 GFILKPQFMFEEG-----YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASP---F 1097
            G++ KP F+ ++G     ++P     ++  +K V V L    +     +   + SP   +
Sbjct: 392  GYVKKPNFLIQKGPQDEVFDPKIALPVKKTLK-VKVYLGKGWSLDFSPSDFDSYSPPDFY 450

Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157
            V+V I+G   D  +K  T  +S+N   P+WN+  +F +  PELAL+   V+++D   + +
Sbjct: 451  VKVCIVGVPADM-IKKKTSVISNNWF-PVWNEEFDFPLTVPELALLGIEVREDDKHQKDD 508

Query: 1158 FIGQATFPLLCLRKGYRSVPL 1178
            F GQ   P+  L+ G+RSVPL
Sbjct: 509  FGGQTCLPVSELKSGFRSVPL 529


>UniRef50_UPI0000F1F9F9 Cluster: PREDICTED: similar to
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            beta 1 (Phosphoinositide phospholipase C) (Phospholipase
            C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154); n=1; Danio
            rerio|Rep: PREDICTED: similar to
            1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase
            beta 1 (Phosphoinositide phospholipase C) (Phospholipase
            C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) - Danio rerio
          Length = 354

 Score =  123 bits (297), Expect = 3e-26
 Identities = 76/198 (38%), Positives = 117/198 (59%), Gaps = 14/198 (7%)

Query: 936  KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994
            +E+S+L+ Y + V F N E  +     Y EMSSF ETKA  L+ +     F++Y+  QLS
Sbjct: 100  EEMSNLVNYVQPVKFTNFETCKKVNRSY-EMSSFVETKAMDLLKESP-VEFIEYNKLQLS 157

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054
            RIYPKG R+DSSNYNP  FWN G Q+VALN+QT    + +   +      C  +LKP+FM
Sbjct: 158  RIYPKGTRVDSSNYNPQVFWNAGCQLVALNFQT----LGIFCPRLSAYCVCVCVLKPEFM 213

Query: 1055 --FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112
               ++ ++P  + +++G +   T+ L++I  + L +   G    +VEVE+IG   D+  K
Sbjct: 214  RRMDKQFDPFTQSTVDGIIAH-TLSLKIISGQFLSEKRVGV---YVEVEMIGLPVDTRWK 269

Query: 1113 LV-TKTVSDNGLNPLWND 1129
               TK+   N +NP+W++
Sbjct: 270  AFRTKSSQGNAINPVWDE 287


>UniRef50_Q762E2 Cluster: Phosphoinositide-specific phospholipase C;
           n=1; Physcomitrella patens|Rep:
           Phosphoinositide-specific phospholipase C -
           Physcomitrella patens (Moss)
          Length = 639

 Score =  123 bits (297), Expect = 3e-26
 Identities = 60/151 (39%), Positives = 88/151 (58%), Gaps = 1/151 (0%)

Query: 281 PYFTLSEFVEMLYSKQNSIYDSQYDKV-TQDMTRPLSHYWISSSHNTYLTGDQFSSESSL 339
           P F ++ F++ L   + + +     K  T DM  PLS Y+I SSHNTYL G+Q  S SS 
Sbjct: 119 PTFDIATFLKFLLHPEFNGHRVPVSKTPTDDMNAPLSDYYIFSSHNTYLMGNQLCSPSST 178

Query: 340 EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399
              V+ L  GCR IELDCW+G +    + HG TLT  + F D ++ IK++AF TS YP++
Sbjct: 179 APIVKALLDGCRVIELDCWNGSNKRIDVLHGGTLTKAVPFEDCVKAIKDNAFTTSAYPVV 238

Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHP 430
           ++IE +  L  Q+  A     + G+++ V P
Sbjct: 239 VTIESHLDLEHQKEAARVLNKILGNIMFVPP 269



 Score = 98.3 bits (234), Expect = 1e-18
 Identities = 64/223 (28%), Positives = 113/223 (50%), Gaps = 8/223 (3%)

Query: 965  MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024
            M++  E++ + L+    ++  +++  T L+R+YP G R+ SSN +P+  W  G Q+ A+N
Sbjct: 407  MANLSESQLDDLIEDHTDSL-IEFSKTNLTRVYPFGLRVTSSNADPMDAWEHGVQVAAIN 465

Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084
             Q  D+P+ ++   F +NGGCG++ KP  +  E  +  D KS+      + + + V+   
Sbjct: 466  MQGRDRPVWISKAIFSRNGGCGYVKKPDILLPE--SNMDHKSLMNLQPKLELKVTVLLGT 523

Query: 1085 HLCKTGRGTASP--FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWN-DICEFEVANPELA 1141
               K       P  FV+V I G  +D   K  T  V      P W  +   F++  P+LA
Sbjct: 524  DWHKNYDVFKKPGYFVKVAIHGM-HDDEQKFKTH-VCKRSREPHWEVEEFVFQIRVPKLA 581

Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184
            ++R  V++ D     + +GQ+  P+   R+G R+V L +   E
Sbjct: 582  ILRLEVREYDRIVRDDMVGQSCVPVTEHRQGIRAVQLASKKGE 624


>UniRef50_Q56W08 Cluster: Phosphoinositide-specific phospholipase C;
            n=6; core eudicotyledons|Rep: Phosphoinositide-specific
            phospholipase C - Arabidopsis thaliana (Mouse-ear cress)
          Length = 564

 Score =  123 bits (296), Expect = 3e-26
 Identities = 80/226 (35%), Positives = 119/226 (52%), Gaps = 7/226 (3%)

Query: 977  MSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNM 1036
            M +   T  V++    L RIYPKG R+DSSNY+P   W  G+QMVA N Q   K + +  
Sbjct: 334  MVRTRGTDLVRFTQRNLVRIYPKGTRVDSSNYDPHVGWTHGAQMVAFNMQGHGKQLWIMQ 393

Query: 1037 GKFKQNGGCGFILKPQFMFEEG--YNPCDKKSIEG--KVKPVTVMLRVIGARHLCKTGRG 1092
            G F+ NGGCG++ KP+ + +E   ++PC +  I+   KVK  T     +   H       
Sbjct: 394  GMFRGNGGCGYVKKPRILLDEHTLFDPCKRFPIKTTLKVKIYTGEGWDLDFHHTHFDQYS 453

Query: 1093 TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDED 1151
                FV++ I G   D+ V   T+T  D    P+W ND   F+++ PELAL+ F VQD D
Sbjct: 454  PPDFFVKIGIAGVPRDT-VSYRTETAVDQWF-PIWGNDEFLFQLSVPELALLWFKVQDYD 511

Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
               + +F GQ   PL  L+ G R+V L +   +  + + L+V  ++
Sbjct: 512  NDTQNDFAGQTCLPLPELKSGVRAVRLHDRTGKAYKNTRLLVSFAL 557



 Score =  107 bits (256), Expect = 2e-21
 Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 3/160 (1%)

Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344
           L+ F   L+S  NS       +V  DM  PLSHY++ + HN+YLTG+Q +S SS+E  V+
Sbjct: 83  LNAFYRYLFSDTNSPLPMS-GQVHHDMKAPLSHYFVYTGHNSYLTGNQVNSRSSVEPIVQ 141

Query: 345 CLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIE 403
            LR G + IELD W  P G    + HG TLT+       L  IK++AF  S+YP+I+++E
Sbjct: 142 ALRKGVKVIELDLWPNPSGNAAEVRHGRTLTSHEDLQKCLTAIKDNAFHVSDYPVIITLE 201

Query: 404 DNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           D+     Q ++A      +  +L    + ++    PSP +
Sbjct: 202 DHLPPKLQAQVAKMLTKTYRGMLF-RRVSESFKHFPSPEE 240


>UniRef50_Q8GV43 Cluster: Phosphoinositide-specific phospholipase C 8;
            n=28; Magnoliophyta|Rep: Phosphoinositide-specific
            phospholipase C 8 - Arabidopsis thaliana (Mouse-ear
            cress)
          Length = 544

 Score =  122 bits (293), Expect = 8e-26
 Identities = 78/235 (33%), Positives = 123/235 (52%), Gaps = 12/235 (5%)

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026
            S  E + +R  S       V++    L RIYPKG R +SSNY P+  W  G+QM+A N Q
Sbjct: 309  SLSEQELDRTCSSNSQDV-VRFTQRNLLRIYPKGTRFNSSNYKPLIGWTHGAQMIAFNMQ 367

Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG-----YNPCDKKSIEGKVKPVTVMLRVI 1081
               K + +  G F+ NGGCG++ KP F+ ++G     ++P  K  ++  +K V V +   
Sbjct: 368  GYGKSLWLMHGMFRANGGCGYVKKPNFLMKKGFHDEVFDPRKKLPVKETLK-VKVYMGDG 426

Query: 1082 GARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANP 1138
                   T     SP   + ++ I+G   D+  K  TK + DN   P+W++   F +  P
Sbjct: 427  WRMDFSHTHFDAYSPPDFYTKMFIVGVPADN-AKKKTKIIEDNWY-PIWDEEFSFPLTVP 484

Query: 1139 ELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193
            ELAL+R  V++ D+  + +F GQ   P+  LR G RSVPL +   E+++   L++
Sbjct: 485  ELALLRIEVREYDMSEKDDFGGQTCLPVAELRPGIRSVPLYDKKGEKMKSVRLLM 539



 Score =  117 bits (282), Expect = 2e-24
 Identities = 57/136 (41%), Positives = 85/136 (62%), Gaps = 2/136 (1%)

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           V QDMT PLSHY+I + HN+YLTG+Q SS+ S    ++ L+ G R IELD W    GT  
Sbjct: 66  VHQDMTAPLSHYFIYTGHNSYLTGNQLSSDCSEVPVIKALQRGVRVIELDLWPNSTGTDI 125

Query: 367 -IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425
            + HG TLTT +  M  L++I+++AF +S YP+I+++ED+ +   Q ++A     +FG  
Sbjct: 126 NVLHGRTLTTPVPLMKCLKSIRDYAFSSSPYPVIITLEDHLTPDLQAKVAEMATQIFGQ- 184

Query: 426 LLVHPMDKNETSLPSP 441
           +L +P   +    PSP
Sbjct: 185 MLYYPESDSLLEFPSP 200


>UniRef50_UPI0000E493BE Cluster: PREDICTED: similar to
            ENSANGP00000003004, partial; n=1; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to ENSANGP00000003004,
            partial - Strongylocentrotus purpuratus
          Length = 354

 Score =  120 bits (289), Expect = 2e-25
 Identities = 73/210 (34%), Positives = 117/210 (55%), Gaps = 24/210 (11%)

Query: 1002 RIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNP 1061
            RIDSSNYNP  +W+ G Q+VALNYQT D  +Q     F++ G CG++LKP  +++  +  
Sbjct: 2    RIDSSNYNPFIYWSFGVQLVALNYQTDDPSLQTYFAMFERTGNCGYVLKPTILWDRNHPA 61

Query: 1062 CDK-----KSIEG-KVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115
             ++     KS +G  +K +T+  +++  + L  T     S FVEVE++G   D   K  T
Sbjct: 62   FNRFNAYNKSFDGMPIKELTI--QIVSGQFLSLT-NPLGSVFVEVEVMGIPADC-AKWKT 117

Query: 1116 KTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK---- 1171
            K  S N +NP+W +   F+V+  +LA +RF V D +     + + Q + PL+ LR+    
Sbjct: 118  KIASRNSINPIWEETFTFQVSFEDLAFVRFTVIDSN---SSSTLAQRSVPLVHLRQDKDG 174

Query: 1172 -------GYRSVPLTNAFSEELELSTLMVH 1194
                   GYR + L ++ +  LE++TL +H
Sbjct: 175  DNAIDLTGYRHLRLRSSQNIPLEITTLFIH 204


>UniRef50_A7T500 Cluster: Predicted protein; n=4; cellular
            organisms|Rep: Predicted protein - Nematostella vectensis
          Length = 171

 Score =  118 bits (285), Expect = 7e-25
 Identities = 76/181 (41%), Positives = 103/181 (56%), Gaps = 23/181 (12%)

Query: 1021 VALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV 1080
            VALNYQT  + +Q+N GKF+ NG CG++LKP  +       C K   EG+ +     L  
Sbjct: 1    VALNYQTEGRMLQINRGKFRANGNCGYVLKPDIL-------C-KGMTEGEGEGGYQTLY- 51

Query: 1081 IGARHLCK---TGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137
                +LCK    G G   P+VEVEIIG   D+  K  TKTV DNG NP+W +   F +  
Sbjct: 52   ----NLCKGMTEGGGIIDPYVEVEIIGIPADTS-KYRTKTVIDNGFNPVWEETMVFLLNF 106

Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            P++AL+RFVV DED  G  +FIGQ T P   +  G+R V L     E L+ +T+  H++I
Sbjct: 107  PDIALVRFVVWDEDPIGR-DFIGQMTLPFQSIMPGFRHVHL-----EGLDQATVFCHVTI 160

Query: 1198 I 1198
            +
Sbjct: 161  M 161


>UniRef50_Q4YWB8 Cluster: Phospholipase C-like, putative; n=4;
           Plasmodium (Vinckeia)|Rep: Phospholipase C-like,
           putative - Plasmodium berghei
          Length = 1312

 Score =  118 bits (284), Expect = 1e-24
 Identities = 66/165 (40%), Positives = 94/165 (56%), Gaps = 5/165 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           Y T    V  L SK+NSI   +Y KV Q+M  PL +YWI+SSHN+YL+  Q  S SS+E 
Sbjct: 553 YLTQIGLVYFLLSKENSIMCPEYAKVYQNMNLPLCNYWINSSHNSYLSRKQIFSASSIEQ 612

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
           Y+  L  GCRC+E DC+   +    +YH   G+ LT+ I F D L   K   F TS YP+
Sbjct: 613 YIYILIDGCRCVEFDCYYF-NKNIVVYHGLYGYKLTSSILFCDTLIACKMFGFSTSPYPI 671

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           ILS+E +C    +  +A     + G+ L + P  K+E +  +P++
Sbjct: 672 ILSLEIHCKDKHKNLIAKILIYILGNQLYI-PKTKDEINNITPNN 715



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 42/95 (44%), Positives = 62/95 (65%), Gaps = 3/95 (3%)

Query: 962  YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021
            YNE+ S  E K  +L+ + E+   +KY+   L+R+YP G R+ S+N+NP+ FW+ G Q V
Sbjct: 950  YNEICSISENKFIKLIKKHEDDV-IKYNQKTLTRVYPSGTRLASTNFNPLIFWSAGIQFV 1008

Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054
            ALNYQ     M +N G+F +NGG   G+ILKP+ +
Sbjct: 1009 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPELL 1043


>UniRef50_Q944C1 Cluster: Phosphoinositide-specific phospholipase C;
           n=8; Magnoliophyta|Rep: Phosphoinositide-specific
           phospholipase C - Arabidopsis thaliana (Mouse-ear cress)
          Length = 597

 Score =  117 bits (281), Expect = 2e-24
 Identities = 82/284 (28%), Positives = 133/284 (46%), Gaps = 10/284 (3%)

Query: 198 EKRGEIGFDDFAVLY-QKLIFDENN-VQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDN 255
           E + E+G   F +++ +K    E+  V+D+ D +  Y      ++  + Q  + +E  + 
Sbjct: 2   EGKKEMGSYKFCLIFTRKFRMTESGPVEDVRDLFEKYTEGDAHMSPEQLQKLMTEEGGEG 61

Query: 256 LGDDEVQASQFIRDYLRDPQR--DIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313
               E +A + + + LR             TL +F   L+S    +     D+V Q+M  
Sbjct: 62  ETSLE-EAERIVDEVLRRKHHIAKFTRRNLTLDDFNYYLFS--TDLNPPIADQVHQNMDA 118

Query: 314 PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373
           PLSHY+I + HN+YLTG+Q SS  S       LR G R +ELD W        + HG TL
Sbjct: 119 PLSHYFIFTGHNSYLTGNQLSSNCSELPIADALRRGVRVVELDLWPRGTDDVCVKHGRTL 178

Query: 374 TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433
           T +++    L +IK +AF  S+YP+I+++ED+ +   Q ++A      FGD+L  H   +
Sbjct: 179 TKEVKLGKCLESIKANAFAISKYPVIITLEDHLTPKLQFKVAKMITQTFGDMLYYHD-SQ 237

Query: 434 NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQ--EEGKDLD 475
                PSP +             E  E +    +   E+GKD D
Sbjct: 238 GCQEFPSPEELKEKILISTKPPKEYLEANDTKEKDNGEKGKDSD 281



 Score =  116 bits (278), Expect = 5e-24
 Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 9/220 (4%)

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            +++      RIYPKG R +SSNY P   W  G+QM+A N Q   + + +  G F+ NGGC
Sbjct: 380  IRFTQKNFLRIYPKGTRFNSSNYKPQIGWMSGAQMIAFNMQGYGRALWLMEGMFRANGGC 439

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV-IGARHLC---KTGRGTASP---FV 1098
            G++ KP F+ +   N  D    +      T+ ++V +G   L    KT   + SP   FV
Sbjct: 440  GYVKKPDFLMDASPNGQDFYPKDNSSPKKTLKVKVCMGDGWLLDFKKTHFDSYSPPDFFV 499

Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158
             V I GA  D  V   TK   D    P+WN    F +A PELAL+R  V + D+  + +F
Sbjct: 500  RVGIAGAPVDE-VMEKTKIEYDT-WTPIWNKEFTFPLAVPELALLRVEVHEHDVNEKDDF 557

Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
             GQ   P+  +R+G R+VPL N    +   + L++    +
Sbjct: 558  GGQTCLPVSEIRQGIRAVPLFNRKGVKYSSTRLLMRFEFV 597


>UniRef50_Q9LUZ0 Cluster: Phosphoinositide-specific phospholipase
            C-line; n=37; Magnoliophyta|Rep:
            Phosphoinositide-specific phospholipase C-line -
            Arabidopsis thaliana (Mouse-ear cress)
          Length = 909

 Score =  116 bits (280), Expect = 3e-24
 Identities = 72/207 (34%), Positives = 104/207 (50%), Gaps = 9/207 (4%)

Query: 978  SQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037
            ++   T  +K+    L RIYPK  R++SSNY P   W  G+QMVA N Q   + + +  G
Sbjct: 353  TEMYGTEVIKFTQKNLLRIYPKATRVNSSNYRPYNGWMYGAQMVAFNMQGYGRALWMMHG 412

Query: 1038 KFKQNGGCGFILKPQFMFE-----EGYNPCDKKSIEGKVKPVTVMLR--VIGARHLCKTG 1090
             F+ NGGCG++ KP FM       E +NP  K  I+  +K    M +    G +  C   
Sbjct: 413  MFRGNGGCGYVKKPDFMMNNNLSGEVFNPKAKLPIKKTLKVKVYMGKGWDSGFQRTCFNT 472

Query: 1091 RGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDE 1150
              + + +  V I G   D  +K   K        P WN+  EF++  PELAL+R  V D 
Sbjct: 473  WSSPNFYTRVGITGVRGDKVMKKTKK--EQKTWEPFWNEEFEFQLTVPELALLRIEVHDY 530

Query: 1151 DIFGEPNFIGQATFPLLCLRKGYRSVP 1177
            ++  + +F GQ   P+  LR+G RSVP
Sbjct: 531  NMPEKDDFSGQTCLPVSELRQGIRSVP 557



 Score =  113 bits (272), Expect = 3e-23
 Identities = 65/163 (39%), Positives = 92/163 (56%), Gaps = 10/163 (6%)

Query: 285 LSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
           L +F   L+S   N   DS   KV QDM  PLSHY+I +SHN+YLTG+Q +SE S    +
Sbjct: 90  LDDFFSFLFSDDLNHPIDS---KVHQDMASPLSHYFIYTSHNSYLTGNQINSECSDVPLI 146

Query: 344 RCLRSGCRCIELDCWDGPDGTP---FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLIL 400
           + L+ G R +ELD W  P+ T     + HG   T  +  +  LR+IKEHAF  S YP+IL
Sbjct: 147 KALKRGVRALELDMW--PNSTKDDILVLHGWAWTPPVELVKCLRSIKEHAFYASAYPVIL 204

Query: 401 SIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           ++ED+ +   Q + A   +++F D ++  P        PSP D
Sbjct: 205 TLEDHLTPDLQAKAAEMMKEIFMD-MVYFPEAGGLKEFPSPED 246


>UniRef50_A5K7G0 Cluster: Phospholipase C-like, putative; n=3;
           Plasmodium|Rep: Phospholipase C-like, putative -
           Plasmodium vivax
          Length = 1432

 Score =  116 bits (280), Expect = 3e-24
 Identities = 64/165 (38%), Positives = 93/165 (56%), Gaps = 5/165 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           Y T    V  L SK+NSI   +Y KV Q+M  PL +YWI+SSHNTYL   Q  S S++E 
Sbjct: 615 YLTQIGLVYFLLSKENSIMCPEYSKVYQNMNLPLCNYWINSSHNTYLGRKQIFSSSNIEQ 674

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
           Y+  L  GCRC+E DC+   +    +YH   G+ LT+ I F D L   K   F TS +P+
Sbjct: 675 YIYILIDGCRCVEFDCYYF-NKNIVVYHGFYGYKLTSSILFCDTLIACKLFGFTTSPFPI 733

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           ILS+E +C    +  +A     + G+ L + P  ++E +  +P++
Sbjct: 734 ILSLEIHCKNKHKNLIAKILICILGNQLYI-PKSRDEINNITPNN 777



 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 42/95 (44%), Positives = 61/95 (64%), Gaps = 3/95 (3%)

Query: 962  YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021
            YNE+ S  E K  +L+ + E    +KY+   L+R+YP G R+ S+N+NP+ FW+ G Q V
Sbjct: 1039 YNEICSISENKFIKLIKKNEEEI-IKYNQKTLTRVYPSGTRLASTNFNPLIFWSAGIQFV 1097

Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054
            ALNYQ     M +N G+F +NGG   G+ILKP+ +
Sbjct: 1098 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPEIL 1132



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 29/81 (35%), Positives = 48/81 (59%), Gaps = 3/81 (3%)

Query: 1123 LNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180
            LN  W+   I + ++  P LALI F ++  D   +   I  A FP+ CLR+G R VPL +
Sbjct: 1352 LNYCWSKPSIFQMKITYPSLALIVFELKTYDTV-KSELIACACFPVKCLREGIRFVPLCD 1410

Query: 1181 AFSEELELSTLMVHLSIITDG 1201
             + ++++ S ++V+L I T+G
Sbjct: 1411 KYLKDIKGSGILVNLKIGTNG 1431


>UniRef50_Q8IJR0 Cluster: Phospholipase C-like, putative; n=1;
           Plasmodium falciparum 3D7|Rep: Phospholipase C-like,
           putative - Plasmodium falciparum (isolate 3D7)
          Length = 1357

 Score =  116 bits (279), Expect = 4e-24
 Identities = 64/165 (38%), Positives = 92/165 (55%), Gaps = 5/165 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           Y T    V  L SK+NSI   +Y KV Q+M  PL +YWI+SSHN+YL   Q  S S++E 
Sbjct: 597 YLTEIGLVYFLLSKENSIMCPEYAKVYQNMNLPLCNYWINSSHNSYLARKQIFSTSNIEQ 656

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
           Y+  L  GCRC+E DC+   +    +YH   G+ LT+ I F D L   K   F TS YP+
Sbjct: 657 YIYILLDGCRCVEFDCYYF-NKNIVVYHGFYGYKLTSSILFCDTLIACKMFGFTTSPYPI 715

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           ILS+E +C    +  +A     + G+ L + P   +E +  +P++
Sbjct: 716 ILSLEIHCKNKHKNLIAKILISILGNQLYI-PKTTDEINNITPNN 759



 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 44/95 (46%), Positives = 63/95 (66%), Gaps = 3/95 (3%)

Query: 962  YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021
            YNE+ S  E K  +L+ + EN   +KY+   L+R+YP G R+ S+N+NP+ FWN G Q+V
Sbjct: 993  YNEICSISENKFIKLIKKNENEI-IKYNQKTLTRVYPSGTRLASTNFNPLIFWNAGIQVV 1051

Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054
            ALNYQ     M +N G+F +NGG   G+ILKP+ +
Sbjct: 1052 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPELL 1086


>UniRef50_A5AGR6 Cluster: Putative uncharacterized protein; n=1; Vitis
            vinifera|Rep: Putative uncharacterized protein - Vitis
            vinifera (Grape)
          Length = 592

 Score =  116 bits (278), Expect = 5e-24
 Identities = 75/213 (35%), Positives = 107/213 (50%), Gaps = 24/213 (11%)

Query: 986  VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045
            +++    L R++PK  R+DSSNYNP+  W  G+QMVA N Q  D+P+ +  G F+ NGGC
Sbjct: 404  IRFTQRNLLRVFPKVMRVDSSNYNPLIGWMHGAQMVAFNMQGYDRPLWLMQGMFRANGGC 463

Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGA 1105
            G++ KP  + + G  P DK        PV   L+                    V I G 
Sbjct: 464  GYVKKPDLLLKVG--PHDKVFDPKANLPVKTTLK--------------------VGIAGV 501

Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165
              DS +K  TK V D+   P WN+  EF +  PELAL+R  V + D+  + +F GQ   P
Sbjct: 502  PADSLMK-KTKAVEDD-WTPTWNEEFEFPLTAPELALLRIEVHEYDMSEKDDFGGQTCLP 559

Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
            +  LR G R+VPL N   E+     L++    +
Sbjct: 560  VSELRTGIRAVPLHNQKGEKYNSVKLLMRFEFV 592



 Score =  111 bits (266), Expect = 1e-22
 Identities = 76/219 (34%), Positives = 112/219 (51%), Gaps = 13/219 (5%)

Query: 229 YSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQR-DIYE--PYF 283
           ++ Y   G  ++L + Q FL + Q    G+DE      Q I D L + +   I++     
Sbjct: 31  FNDYSEEGV-MSLEQLQKFLIEVQ----GEDEASMEDVQGIMDSLHEFKHLPIFQLRKGL 85

Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343
            L  F   L    N    S ++ V  DM  PLSHY+I + HN+YLTG+Q SS  S    +
Sbjct: 86  NLEAFFRYLCHDLNPPL-SPHNTVHHDMNAPLSHYFIYTGHNSYLTGNQLSSICSDVPVI 144

Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402
             L+ G R IELD W         + HG TLTT ++    L +IK++AF+ SEYP+I+++
Sbjct: 145 NSLQCGVRVIELDMWPNSTKDDIDVLHGRTLTTPVKLSKCLISIKKYAFVASEYPVIITL 204

Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
           ED+ +   Q ++A     +FGDLL   P  +     PSP
Sbjct: 205 EDHLTPDLQAKVAEMATQIFGDLLF-SPESECLAEFPSP 242


>UniRef50_Q9AXF1 Cluster: Phosphoinositide-specific phospholipase C;
           n=3; Oryza sativa|Rep: Phosphoinositide-specific
           phospholipase C - Oryza sativa (Rice)
          Length = 599

 Score =  114 bits (275), Expect = 1e-23
 Identities = 64/162 (39%), Positives = 90/162 (55%), Gaps = 3/162 (1%)

Query: 284 TLSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342
           T+ +F   L+S + N        +V  DM  PLSHY+I + HN+YLTG+Q SS+ S    
Sbjct: 89  TVDDFHRFLFSHELNPPIRHGQGQVHHDMAAPLSHYFIYTGHNSYLTGNQLSSDCSDLPI 148

Query: 343 VRCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401
           +R L+ G R IELD W         I HG T TT +  +  L +IKEHAF  S YP+I++
Sbjct: 149 IRALQRGVRVIELDMWPNSSKDDISILHGRTPTTPVSLLKCLLSIKEHAFEASPYPVIIT 208

Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443
           +ED+ +   Q + A    +VFGD +L +P   +    PSP D
Sbjct: 209 LEDHLTPDLQDKAAKMVLEVFGD-ILYYPDKDHLKEFPSPQD 249



 Score =  113 bits (271), Expect = 4e-23
 Identities = 79/234 (33%), Positives = 117/234 (50%), Gaps = 15/234 (6%)

Query: 958  KGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ--------LSRIYPKGQRIDSSNYN 1009
            KG + + + S PE      +S+Q+      +H T+        L RIYPKG R+ SSNYN
Sbjct: 348  KGTLLDALQSDPEKVRRLSLSEQQLAKLADHHGTEIVRFTQRNLLRIYPKGTRVTSSNYN 407

Query: 1010 PVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCD-KKSIE 1068
            P   W  G+QMVA N Q   + + +  G +K NGGCG++ KP F+ +      D KKS+ 
Sbjct: 408  PFLGWVHGAQMVAFNMQGYGRALWLMHGFYKANGGCGYVKKPDFLMQTDPEVFDPKKSLS 467

Query: 1069 G-KVKPVTVMLRVIGARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLN 1124
              K   V V +         +T     SP   +  V I G   DS +K  T+ + DN + 
Sbjct: 468  SKKTLKVKVYMGDGWRMDFTQTHFDQYSPPDFYARVGIAGVPADSVMKR-TRAIEDNWV- 525

Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
            P+W +   F++  PE+AL+R  V + D+  + +F GQ   P+  L  G R+V L
Sbjct: 526  PVWEEDFTFKLTVPEIALLRVEVHEYDMSEKDDFGGQTVLPVSELIPGIRAVAL 579


>UniRef50_A6RM87 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 1023

 Score =  113 bits (273), Expect = 2e-23
 Identities = 90/283 (31%), Positives = 140/283 (49%), Gaps = 35/283 (12%)

Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224
           E +  + V+     ++   S+  LR+ FQ  D  K  ++ F +F   + KL+    +V +
Sbjct: 399 EALDFEGVEQLCKNLHINTSSRFLRERFQQADATKSKKLIFSEFQE-FVKLMKRRGDVSE 457

Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ-ASQFIRDYLRDPQRD--IYEP 281
           I+ + +    N   ITL EF +F+   Q +N+  D  +  S F +   R   RD  + E 
Sbjct: 458 IYRELA--SDNVKGITLEEFIDFVNVVQGENVEKDRAKWESIFAKFARRSRSRDQPLQEG 515

Query: 282 YFT-LSEFVEMLYSKQNSIYDSQYDKVTQDMT--RPLSHYWISSSHNTYLTGDQFSSESS 338
               +SE  E L +   S+++   + V +  T  RP+  Y+ISSSHNTYL G Q + ESS
Sbjct: 516 EAARMSE--EALATFFTSVHNVPLETVPETFTLDRPMHEYFISSSHNTYLMGRQVAGESS 573

Query: 339 LEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398
           +EAY+  L  GCR                         I F DV+ TI ++AF+ S +PL
Sbjct: 574 VEAYISALIKGCR------------------------PIMFSDVMYTIAKYAFVKSHFPL 609

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441
            +S+E +C+  QQ  MA   ++  GDLL+  P+D +   LPSP
Sbjct: 610 WISLEVHCNDAQQAAMAQIIKEACGDLLVTEPLDPSSQVLPSP 652



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 6/89 (6%)

Query: 1115 TKTVSDNGLNPLWNDICEFEVAN--PELALIRFVVQ---DEDIFGEPNF-IGQATFPLLC 1168
            T  V +NG NP++N    F +    PEL  +R+ V+   D   + +    +   T  L  
Sbjct: 892  THIVQENGFNPVFNKKFNFALTTKFPELVFVRWTVRCSSDGHSYNDKTLPLATYTAKLSS 951

Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            L++GYR++PL +   ++   STL   + I
Sbjct: 952  LKQGYRTLPLYDTNGDQFLFSTLFCRVKI 980


>UniRef50_Q9XWB7 Cluster: Putative uncharacterized protein plc-2;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein plc-2 - Caenorhabditis elegans
          Length = 896

 Score =  110 bits (265), Expect = 2e-22
 Identities = 80/230 (34%), Positives = 117/230 (50%), Gaps = 19/230 (8%)

Query: 217 FDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDN-LGDDEVQ--ASQFIRDYLRD 273
           F+ + ++ IF K S    +    T  EF ++LR  QHD+ L D      + + I   L +
Sbjct: 211 FEGSRLEAIFRKIS---EDEPVATKLEFGDWLRKNQHDHRLNDARFNQVSDRKINSILEN 267

Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSI-YDSQYDKV-TQDMTRPLSHYWISSSHNTYLTGD 331
            Q    +   +   F   + S +  +   +Q  K+    M  P++ Y+I+SSHNTY +G+
Sbjct: 268 WQYSS-DSAISPQMFTHWMVSDECGVAISAQRMKMDVTSMREPINKYFINSSHNTYCSGN 326

Query: 332 QF-----SSESSLEAYVRCLRSGCRCIELDCWDGPD--GTPFIYHGHTLT---TKIRFMD 381
           Q         + +E Y + L SG RC+ELD WD  D  G P I HG T      +I   +
Sbjct: 327 QLVYAIGHCSADVEMYRQALLSGSRCVELDMWDNKDKDGEPVITHGPTAVMGMNEIGLKE 386

Query: 382 VLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPM 431
           V   IKE AF TS YP+ILSIE++    QQ +M   F+ VFG+LLL  P+
Sbjct: 387 VCEAIKECAFKTSPYPVILSIENHLGRKQQEKMVQIFRQVFGELLLTGPL 436



 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 33/64 (51%), Positives = 47/64 (73%)

Query: 991  TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050
            ++++RIYPK  RI S+NYNP+  W  GSQMV+LN QT    MQ+N   F++NGGCG++ K
Sbjct: 587  SKITRIYPKASRIYSTNYNPMIHWLTGSQMVSLNIQTNCSNMQLNYAMFERNGGCGYVRK 646

Query: 1051 PQFM 1054
            P ++
Sbjct: 647  PDWL 650


>UniRef50_Q236T7 Cluster: Phosphatidylinositol-specific
           phospholipase C, X domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep:
           Phosphatidylinositol-specific phospholipase C, X domain
           containing protein - Tetrahymena thermophila SB210
          Length = 1278

 Score =  109 bits (263), Expect = 3e-22
 Identities = 105/414 (25%), Positives = 190/414 (45%), Gaps = 55/414 (13%)

Query: 67  EGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKEC 126
           E  + + ++K +++  S  +   +         S C T+  G E  L          K  
Sbjct: 105 ESRIKLSEIKNIQSKPSLTEINNYDSSV-----SLCLTMDGGFELILEF-----NDKKTR 154

Query: 127 EAWVKGVLYLIAEAVSASYPLQI----ERWLRKEFYSIE-NSHEKITLKEVKAFLPKINC 181
           + W KG+L++  +     Y +Q     E+++ +     E +  +KIT KEVK  L K+  
Sbjct: 155 DKWWKGLLFV--KEYGPDYDIQNYQTKEQFIAQLLLGAEIDKKKKITDKEVKKLLRKLLI 212

Query: 182 KISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITL 241
           +I+  +L D  +         + +++F  L   L+ ++  +Q I   Y  YC+N   I  
Sbjct: 213 QINNEELEDKIKKYYKNNEKSLTYNEFIELTITLL-EKPEIQPI---YQSYCTNNNMILQ 268

Query: 242 REFQNFLRDEQHDNLGDDEVQAS---------QFIRDYLR-------------DPQRDI- 278
           ++   F ++EQ +N  + +V +          + + +YL              DP + + 
Sbjct: 269 KDILKFYQNEQGENYDEKQVLSKMNKLTKGREKKMINYLSFCQLIFTGDNSIFDPAKQVI 328

Query: 279 ---YEPYFTLSEFVEMLYSKQNSIYD---SQ--YDKVTQDMTRPLSHYWISSSHNTYLTG 330
              +E  F L +FV++ +++  + +    SQ  +    Q+M +PLS Y+I+SS  +YL  
Sbjct: 329 SGLFEKDFNL-QFVQINFNQVFNTFQLISSQLFFQYTPQNMDKPLSDYFINSSFRSYLVY 387

Query: 331 DQFSSESSL-EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389
           D  +    L +AY+  L+ G R +++ C DG  G P    G    T +   D+ + IK++
Sbjct: 388 DLVTQTKDLTKAYIYLLQKGVRHLDIYCQDGESGVPEALQGVFQVTPVSVEDIFKAIKQY 447

Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSPH 442
            F  S YP+I+++E  CS+ QQ  +A    +VF D+L   P D      LPSP+
Sbjct: 448 GFERSVYPIIINLEHECSVNQQNLIAQFLVNVFQDMLYRLPEDFISLDYLPSPN 501



 Score =  101 bits (241), Expect = 2e-19
 Identities = 72/228 (31%), Positives = 110/228 (48%), Gaps = 11/228 (4%)

Query: 979  QQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037
            Q+E    +  HT Q L R YPK  + D SNYN +     G Q  A+NY T D  +   + 
Sbjct: 1004 QEEMNQQIVNHTRQYLLRTYPKQAKSDHSNYNFLQTMVSGCQFSAMNYYTQDLYLLAYLQ 1063

Query: 1038 KFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG--RGTA 1094
             FKQN  CG++LKP ++        ++   +   KP + + + +I A+ L   G      
Sbjct: 1064 YFKQNASCGYVLKPPWLLSSTAKTSNQYFEKEASKPKIWLKVEIISAQSLRIPGDEEKIF 1123

Query: 1095 SPFVEVEIIGADYDSGVK---LVTKTVSDNG-LNPLW-NDICEFEVANPELALIRFVVQD 1149
            SP++ + +IG   D        V+  V +N   NP + N I +F V  PELA + F V D
Sbjct: 1124 SPYISIRLIGTALDIQANENLFVSNQVKNNSCYNPQFENCIADFTVYIPELAFVIFQVYD 1183

Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
                 +     Q   P+ C+RKG+R++PL ++    +  S L  H+SI
Sbjct: 1184 NPECQDR--FAQYAIPVSCIRKGFRTIPLLDSQLNPIPNSFLFAHISI 1229


>UniRef50_UPI00015A74B5 Cluster: UPI00015A74B5 related cluster; n=1;
           Danio rerio|Rep: UPI00015A74B5 UniRef100 entry - Danio
           rerio
          Length = 573

 Score =  108 bits (259), Expect = 1e-21
 Identities = 75/207 (36%), Positives = 104/207 (50%), Gaps = 18/207 (8%)

Query: 197 TEKRGEIGFDDFAV-LYQKL---IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252
           T +   I  D F   +Y++L   I   N++  IF   SV     T  ++     F   EQ
Sbjct: 117 TGRNDSIPLDTFTQDVYRQLLNNICPRNDIDTIFSDMSVLFILCTHCSV--LLGFAEREQ 174

Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSE--------FVEMLYSKQNSIYDSQY 304
           H    D  +       + ++    + YEP   LS         F   L  ++N I   + 
Sbjct: 175 HMTEADTPLTXPHLKAEQVQ-ALVEKYEPDSMLSSRGQISVEGFARYLSGEENCIIPPEK 233

Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG--PD 362
             +++D+T+PLSHY+I+SSHNTYL G Q +  SS+E Y + L SGCRC+ELD W G  PD
Sbjct: 234 LDLSEDITQPLSHYFINSSHNTYLIGQQLAGTSSVEIYRQVLLSGCRCVELDVWKGKAPD 293

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEH 389
             P I HG T+TT+I F D L T K H
Sbjct: 294 EEPIITHGFTMTTEISFKDTL-TTKAH 319



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 25/53 (47%), Positives = 35/53 (66%), Gaps = 2/53 (3%)

Query: 977  MSQQENTFFVKYHTTQLSR--IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQT 1027
            + Q E +   + H+T  +   ++ KG R+DSSNYNP  FWN G Q+VALN+QT
Sbjct: 520  VEQSEASPAEEQHSTSCTHTALWXKGTRVDSSNYNPQVFWNAGCQLVALNFQT 572


>UniRef50_A4S165 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 495

 Score =  107 bits (257), Expect = 2e-21
 Identities = 51/120 (42%), Positives = 69/120 (57%)

Query: 311 MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHG 370
           MT  LSHY+++SSHNTYL G Q  S S+  A    L  GCR +ELDC+DG    P I HG
Sbjct: 1   MTDELSHYFVNSSHNTYLDGGQLFSRSTSSAIAWALERGCRVVELDCYDGGSKGPIITHG 60

Query: 371 HTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHP 430
            T    + F D +  I + A + SEYP+I+++E++ S   +  MA   +  FGD L   P
Sbjct: 61  GTAVRPMLFKDAIAVINDRAHVASEYPVIVTLENHASRETRAVMAKIMRHTFGDKLWTPP 120



 Score =  105 bits (251), Expect = 1e-20
 Identities = 63/222 (28%), Positives = 106/222 (47%), Gaps = 15/222 (6%)

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026
            S+ E KA++L+ +      +++    L R YP GQRI S+NY+P   W+ G+ +VALN+Q
Sbjct: 228  SWSENKAKKLVEKSSQKDLLEFTKAHLLRTYPGGQRIMSNNYDPSDAWSIGASLVALNFQ 287

Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL 1086
              D+ M VN  KF  NGGCG++ KP ++     NP  ++  + ++  + V   +      
Sbjct: 288  AQDRYMWVNQAKFAVNGGCGYVKKPDYLI----NPSVQRPTKPRILRIHVFCGLGWENFK 343

Query: 1087 CKTGRGTASPFVEVEIIGADYD------SGVKLVTKTVSDNGL----NPLWNDICEFEVA 1136
                      F+++ + G   D       G  + T   S   +     P+WN+  + E+ 
Sbjct: 344  DADFMSAPDTFMKISLFGCVADRLSATSRGNSMRTSVYSKARVGPCAQPIWNEHFDLEIR 403

Query: 1137 NPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
             PEL +++    D+D      F+      +  LR+G R VPL
Sbjct: 404  EPELTVLQIQAMDKD-GARDEFLAHYDVAVSALREGVRIVPL 444


>UniRef50_UPI0001555F0C Cluster: PREDICTED: hypothetical protein,
           partial; n=2; Amniota|Rep: PREDICTED: hypothetical
           protein, partial - Ornithorhynchus anatinus
          Length = 233

 Score =  103 bits (247), Expect = 3e-20
 Identities = 64/194 (32%), Positives = 104/194 (53%), Gaps = 26/194 (13%)

Query: 701 EIKHCRV--KQEG---RLYTIGTVKFESLIELVSYYENHPLYK---KVKLWYPISEETVR 752
           +++HCR+  +Q+    + +    + F+SL  L+++Y+  PL     +++L  P+ +    
Sbjct: 4   KVQHCRIHSRQDAGSPKFFLTDNLVFDSLYALITHYQQVPLRCNEFEMRLTEPVPQTNAH 63

Query: 753 RLVSEPD-------------DNTVYGTPGYMDPTSFTSKVT----VKALYDYRARQDDEL 795
                P                T    P ++ P   +  ++    VKAL+DY+A+++DEL
Sbjct: 64  ESKDTPSVPPQKLSHCPPNAPCTSRCDPSHLVPPGLSPYLSRQCAVKALFDYKAQREDEL 123

Query: 796 SFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGS 855
           +F K AII NV+K + GWWRGDYGGK+  WFP+NYV E+  P        L+ E++ LG 
Sbjct: 124 TFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMASPALEPEREQLD-ENSPLGD 182

Query: 856 LQKGVLDVLGAIVE 869
           L +GVLDV    +E
Sbjct: 183 LLRGVLDVPSCQIE 196



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 39/67 (58%), Positives = 47/67 (70%)

Query: 590 RQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQP 649
           R GKV HCRI  +Q+ G  KF+L D++ FDSLY LITHY+  PLR  EF + L EPVPQ 
Sbjct: 1   RNGKVQHCRIHSRQDAGSPKFFLTDNLVFDSLYALITHYQQVPLRCNEFEMRLTEPVPQT 60

Query: 650 NKHEGKE 656
           N HE K+
Sbjct: 61  NAHESKD 67


>UniRef50_Q4QBH9 Cluster: Phosphoinositide-specific phospholipase C,
           putative; n=3; Leishmania|Rep: Phosphoinositide-specific
           phospholipase C, putative - Leishmania major
          Length = 555

 Score =  102 bits (244), Expect = 7e-20
 Identities = 53/129 (41%), Positives = 77/129 (59%)

Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366
           V QDM + +  Y+ISSSHNTYLTGDQ +S+SS + Y +         E  C +GP G P 
Sbjct: 191 VYQDMDQIMCCYFISSSHNTYLTGDQLTSKSSAQMYKKGASRRVPVREAICRNGPHGEPI 250

Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426
           + HG+T T+ I F + ++ I+++AF  S Y +ILS+  + S+ QQ +MA   ++  G LL
Sbjct: 251 VCHGYTRTSCIAFEECVKMIRQYAFTASAYLVILSLGVHTSVEQQDKMAEILEEGLGSLL 310

Query: 427 LVHPMDKNE 435
              P   NE
Sbjct: 311 FWPPWGSNE 319



 Score = 75.8 bits (178), Expect = 7e-12
 Identities = 37/90 (41%), Positives = 57/90 (63%), Gaps = 2/90 (2%)

Query: 966  SSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025
            SS+ E K + ++ +  N   V  + T LSR++P G RIDSSNY P+ +W  G QMVA+N+
Sbjct: 420  SSYSERKGKAIVREAHNAL-VCINDTCLSRVFPAGSRIDSSNYRPLLYWVSGCQMVAINW 478

Query: 1026 QTPDK-PMQVNMGKFKQNGGCGFILKPQFM 1054
            Q+ D    ++N   F  +G CG++LKP ++
Sbjct: 479  QSSDTFGWRLNGCIFLDSGCCGYLLKPDYL 508


>UniRef50_Q4SCY7 Cluster: Chromosome 14 SCAF14646, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 14 SCAF14646, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 530

 Score =  101 bits (243), Expect = 9e-20
 Identities = 54/120 (45%), Positives = 71/120 (59%), Gaps = 3/120 (2%)

Query: 262 QASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWIS 321
           +A Q I  Y RD +    +   +   F   L S +N+       ++ Q+M +PL+HY+IS
Sbjct: 179 RAMQIIEKYERDAELK-KKGRMSSDGFCRYLMSDENAPVFLDRLELYQEMDQPLAHYFIS 237

Query: 322 SSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRF 379
           SSHNTYLTG QF  +SS+E Y + L SGCRC+ELDCWD  G D  P I HG  + T I F
Sbjct: 238 SSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDILF 297



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 2/45 (4%)

Query: 1029 DKPMQVNMGKFKQNGGCGFILKPQFM--FEEGYNPCDKKSIEGKV 1071
            D  MQ+N GKF+ NG CG++LKP FM   +  ++P  +  ++G +
Sbjct: 451  DLAMQLNQGKFEYNGSCGYLLKPDFMRRSDRTFDPFSEIPVDGVI 495


>UniRef50_A5E691 Cluster: Putative uncharacterized protein; n=1;
            Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
            uncharacterized protein - Lodderomyces elongisporus
            (Yeast) (Saccharomyces elongisporus)
          Length = 538

 Score =  101 bits (241), Expect = 2e-19
 Identities = 75/284 (26%), Positives = 133/284 (46%), Gaps = 21/284 (7%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQ-ENTFFVKYHTT 991
            +I   +S+L +Y + + F    L  +  VYN   S  E    +++  + + T   K++  
Sbjct: 248  KIIDVLSELGVYIQGIKFRNFSLP-ESKVYNHCFSLSEKATNKMLKDEVKRTSLDKHNRK 306

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ-NGGCGFILK 1050
               R+YP   R+ SSN+ P+ +W  G QMVA N+QT D   Q+N   F+  +   G++LK
Sbjct: 307  YFLRVYPSRFRLKSSNFIPINYWKIGVQMVATNWQTYDLGQQLNEAMFEDPHNKSGYVLK 366

Query: 1051 PQFMFEEGYNPCD-KKSIEGKVKPVTVMLRVIGARHL-CKTGRGTASPFVEVEIIGAD-- 1106
            P ++ +         K      + +   + ++GA  L   T     +PFV VE+IGAD  
Sbjct: 367  PSYLRKPIIKSSKFYKMPSPPAEKIKFSITIVGAHELPTSTYADVLNPFVTVEVIGADSI 426

Query: 1107 ----YDSGVKLVTKTVSDNGLNPLWNDICEFEVAN-PELALIRFVV-------QDEDIFG 1154
                 +  +   T+ +++NG +P+W++    E+    +   ++FVV        +   F 
Sbjct: 427  ESDTEEGELGKRTRVINNNGFSPIWDETFNGEITGLRDFIFVKFVVGSYSTPWSESSKFD 486

Query: 1155 --EPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLS 1196
               P  +      L  L++GY+ + L + F E L  S+L V +S
Sbjct: 487  THTPATVAMVVTKLDHLQQGYQHLHLKDPFGERLPFSSLFVKVS 530



 Score = 92.3 bits (219), Expect = 7e-17
 Identities = 64/162 (39%), Positives = 83/162 (51%), Gaps = 32/162 (19%)

Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYV-------RCLR--------SGCRCIELD 356
           + PL+ Y+ISSSHNTYL G Q   ESSLE Y+       RC+          G   + LD
Sbjct: 22  SHPLTDYYISSSHNTYLIGRQVGGESSLEGYIKALKKGCRCVEIDVWDGSGGGASSLVLD 81

Query: 357 CWDGPDGT--------------PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402
                  T              P + HG T T  I+F DV+RTIKE+AF +S YP+ILS+
Sbjct: 82  GNSANTNTNGGTSAATIAVVAEPVVNHGRTFTKSIKFSDVIRTIKEYAFESSPYPVILSL 141

Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSPHD 443
           E NCS   QR + +  ++  G  L+   +  NE S LPSP D
Sbjct: 142 EINCSANYQRSVVTIIKETLGKSLVTETI--NEYSILPSPED 181


>UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma 1 (Phosphoinositide
           phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1)
           (PLC-II) (PLC-148); n=2; Gallus gallus|Rep: PREDICTED:
           similar to 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma 1 (Phosphoinositide
           phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1)
           (PLC-II) (PLC-148) - Gallus gallus
          Length = 174

 Score =  100 bits (239), Expect = 3e-19
 Identities = 56/121 (46%), Positives = 70/121 (57%), Gaps = 6/121 (4%)

Query: 538 ELHFAECWFHGKLAGNR---QEAEDLLRAHA-HLGD--GTFLVRESVTFVGDYCLSFWRQ 591
           ELH A+ WFH KL   R     AE LL  +   +GD  G+FLVRES TFVGDY LS W  
Sbjct: 50  ELHLAQDWFHSKLGEGRVGWHMAEWLLTEYCTEMGDPDGSFLVRESGTFVGDYVLSLWCN 109

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNK 651
            KV HC I   Q+  +++F+L D+  FDSL+N IT YR       +  + L E VP+ N 
Sbjct: 110 EKVQHCCIHWWQDASISRFFLTDNWVFDSLFNFITRYRETLPGYNKLEMRLTEAVPRSNT 169

Query: 652 H 652
           H
Sbjct: 170 H 170



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 16/107 (14%)

Query: 652 HEGKEWFHAHCTRTQ-----AEELLRKTNT-----DGAFLVRPSEKEQGSFAISFRTEKE 701
           H  ++WFH+     +     AE LL +  T     DG+FLVR S    G + +S    ++
Sbjct: 52  HLAQDWFHSKLGEGRVGWHMAEWLLTEYCTEMGDPDGSFLVRESGTFVGDYVLSLWCNEK 111

Query: 702 IKHCRVK--QE---GRLYTIGTVKFESLIELVS-YYENHPLYKKVKL 742
           ++HC +   Q+    R +      F+SL   ++ Y E  P Y K+++
Sbjct: 112 VQHCCIHWWQDASISRFFLTDNWVFDSLFNFITRYRETLPGYNKLEM 158


>UniRef50_Q013R6 Cluster: Phosphoinositide-specific phospholipase C;
            n=1; Ostreococcus tauri|Rep: Phosphoinositide-specific
            phospholipase C - Ostreococcus tauri
          Length = 616

 Score =  100 bits (239), Expect = 3e-19
 Identities = 65/229 (28%), Positives = 109/229 (47%), Gaps = 20/229 (8%)

Query: 967  SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026
            S+ E K +  + ++ +   +++    L R YP G RI S+NY+P   W+ G+  VALN+Q
Sbjct: 378  SWSERKLKLKIEKESSKDIIEFTNAHLLRTYPAGHRIFSNNYDPSEAWDVGASFVALNFQ 437

Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV---IGA 1083
              D+ +  N  KF+ NG CG++ KP ++ +         +IE   KP  + ++V   IG 
Sbjct: 438  ALDRYVWANRAKFRVNGNCGYVKKPAYLLD--------PTIERPSKPRRLQVKVFAGIGW 489

Query: 1084 RHLCKTGR-GTASPFVEVEIIGADYD-------SGVKLVTKTVSDNGLNPLWNDICEFEV 1135
             +     R       + +  +G   D       +   + +K  +     P+WND  E  +
Sbjct: 490  DNFKDADRFSPPDSLIRITTLGCLADRTKPGKSNRTSVYSKARAGPEAQPVWNDTFELAI 549

Query: 1136 ANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184
              PELAL++    D+D  G+   +    FP+  LR+G R VP+ N   E
Sbjct: 550  FEPELALMQIQALDKDGNGD-ELLAHYDFPISKLREGVRIVPMLNRDDE 597



 Score = 94.7 bits (225), Expect = 1e-17
 Identities = 47/121 (38%), Positives = 69/121 (57%), Gaps = 4/121 (3%)

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD----GPDGTP 365
           +MT  +S Y+++SSHNTYL GDQ  S +S+ A    L  GCR IELD +D    G    P
Sbjct: 118 EMTSEMSAYFVNSSHNTYLDGDQLFSRASVAAIAGALDRGCRVIELDVYDGKKRGDKPRP 177

Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425
            + HG T    + F D ++ I E A + SEYP+I+++E++ S   +  M+   +   GD 
Sbjct: 178 IVTHGGTAVRPMYFEDAIKVIAERAHVASEYPVIVTLENHASKETRAEMSRILRSTLGDK 237

Query: 426 L 426
           L
Sbjct: 238 L 238


>UniRef50_A7ASE0 Cluster: Phospholipase C gamma 1, putative; n=1;
           Babesia bovis|Rep: Phospholipase C gamma 1, putative -
           Babesia bovis
          Length = 1027

 Score =  100 bits (239), Expect = 3e-19
 Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 4/150 (2%)

Query: 283 FTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341
           FT+  F   L  K N+    Q  +++   +  PL+ +WI+SSHNTYLTG+Q    ++  A
Sbjct: 493 FTIMGFHWSLAQKFNAATIPQDAEEILNLLKYPLNSFWIASSHNTYLTGNQVGGAAAAGA 552

Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGH---TLTTKIRFMDVLRTIKEHAFITSEYPL 398
               L  GCRCIELDC DGP+G P + H      LT  I   + L   KE AF  S+ P+
Sbjct: 553 LADALLRGCRCIELDCQDGPNGEPVLCHSWKNCQLTGSITLSEALIACKETAFKFSKLPV 612

Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428
           ILS++ +C+   + + A   + + GD L +
Sbjct: 613 ILSMQMHCTDECKMKTAETCRKILGDALYI 642



 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 4/89 (4%)

Query: 963  NEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVA 1022
            N + S  E+K  ++ + Q   F  +     + RIYP G R+ S+N+ P+  W  G Q VA
Sbjct: 710  NNVYSLNESKFAKVAAHQ--AFLRRLTDISMIRIYPSGTRVASTNFCPLNAWASGIQCVA 767

Query: 1023 LNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
            LNYQ+ D+ M +N GKF Q+   G++LKP
Sbjct: 768  LNYQSCDRSMLINYGKFNQS--FGYVLKP 794



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 9/106 (8%)

Query: 1096 PFVEVEIIGADYDSGVKLV-TKTVSDNGLNPLWNDIC---EFEVANPELALIRFVVQDED 1151
            PFVE+ ++G     G +++ T+ V+ NG NP+W D     EF V  P LA++   V+  D
Sbjct: 923  PFVEIVLVG----KGERILKTEIVNFNGFNPVWADTTPPFEFIVKEPNLAVLLLAVKHHD 978

Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
              G    IGQ   P+  +R G R   L +    E+E   L++H+ I
Sbjct: 979  NVGV-QIIGQTALPVNRIRPGIRWAQLLDQRLMEIECCGLLLHIDI 1023


>UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to
           protein-tyrosine phosphatase; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to protein-tyrosine
           phosphatase - Strongylocentrotus purpuratus
          Length = 533

 Score = 98.7 bits (235), Expect = 8e-19
 Identities = 66/196 (33%), Positives = 100/196 (51%), Gaps = 13/196 (6%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  ++G   EAE LL  +    DG FL R S +  GD+ LS  R G+V H +I   Q 
Sbjct: 6   WFHPNISG--MEAEQLLLNNGF--DGCFLCRPSKSNPGDFTLSVRRNGEVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHY---RSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAH 661
            G   F L     F +L  L+ HY   R+        +I LK P+   +    + WFH H
Sbjct: 59  TG-DFFDLYGGEKFATLAELVQHYTEGRNQLKERNGQMIELKYPLNCADP-TNERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI-GTVK 720
            T  +AE+ L     +G++LVR S  + G + +S RTE ++ H  ++ +   Y + G  +
Sbjct: 117 ITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKYDVGGGEQ 176

Query: 721 FESLIELVSYYENHPL 736
           FE+L +LV +Y  +P+
Sbjct: 177 FETLTDLVDHYRKNPM 192



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 1/78 (1%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + +  +AE+LL     DG FL RPS+   G F +S R   E+ H +++  G  +
Sbjct: 4   RRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDFF 63

Query: 715 TI-GTVKFESLIELVSYY 731
            + G  KF +L ELV +Y
Sbjct: 64  DLYGGEKFATLAELVQHY 81



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 37/104 (35%), Positives = 58/104 (55%), Gaps = 9/104 (8%)

Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602
           E WFHG + G  +EAE  L       +G++LVRES +  GDY LS   + KV H  I+ +
Sbjct: 110 ERWFHGHITG--KEAEKSLVDKGK--NGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQ 165

Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEP 645
                TK+ +     F++L +L+ HYR +P+  +  +++ LK P
Sbjct: 166 D----TKYDVGGGEQFETLTDLVDHYRKNPMVETTGYVVHLKVP 205


>UniRef50_Q0UE70 Cluster: Putative uncharacterized protein; n=4;
           Dikarya|Rep: Putative uncharacterized protein -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 573

 Score = 97.5 bits (232), Expect = 2e-18
 Identities = 52/125 (41%), Positives = 69/125 (55%), Gaps = 7/125 (5%)

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG--TPFI 367
           D   PL  Y+ISSSHNTYL   Q   ES   AY   L +G RC+E+D WD  D    P +
Sbjct: 100 DRNHPLPEYFISSSHNTYLMAHQLFGESHASAYEIALYTGSRCVEIDAWDNDDNKEEPKV 159

Query: 368 YHGHTLTTKIRFMDVLRTI-----KEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
            HG+TL + I F  V  T+     KE A      P+++S+E++C    Q R+A   ++VF
Sbjct: 160 THGYTLVSNIPFRTVCETLRDVVDKEAAEERHAAPIMISLENHCDAHGQARLAQIMREVF 219

Query: 423 GDLLL 427
           GD LL
Sbjct: 220 GDRLL 224



 Score = 70.9 bits (166), Expect = 2e-10
 Identities = 59/229 (25%), Positives = 101/229 (44%), Gaps = 26/229 (11%)

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +++   L R++PKG RI S N  PVPFW  G+Q+ ALN+QT     Q+N   F  +G  G
Sbjct: 352  RHNAHHLMRVFPKGTRISSKNLAPVPFWGIGAQICALNWQTFGAASQLNEALFAGSG--G 409

Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-CKTGRGT--ASPFVEVEII 1103
            ++LKP  +   G    D     G+ +   + L V GA  +     R T    P++   ++
Sbjct: 410  YVLKPAALRAGG----DGNLNTGRRR--KLRLHVAGATDVPLPKDRETDDIKPYLTCTMV 463

Query: 1104 GADYDSGVKLVTKTV------------SDN--GLNPLWNDICEFEVANPELALIRFVVQD 1149
                 + + +  KT              DN    +P+W ++ E+E  + EL  +R +++ 
Sbjct: 464  HPSDLNNMPVKRKTAGYKPHKLTSFLHKDNSPSTDPIWKEVLEWEYEDNELVFLRLLIKS 523

Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198
            +D F        A   L+    G+  + + +    E    TL+V    +
Sbjct: 524  DDSFARNPIFAVAAVRLMYAAPGWSFIRMLDLGGHE-TTCTLLVRFEFV 571


>UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep:
           Protein vav-3 - Homo sapiens (Human)
          Length = 847

 Score = 93.9 bits (223), Expect = 2e-17
 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%)

Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704
           VP+P  +  + W+     R QAE EL+ + N+   +LVR   KE G +AIS +   E KH
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718

Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763
            ++  ++G  +     KF+SL+ELV YY++H L    K  +   + T++    EP+ +  
Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773

Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819
            G  G     S  S KV   A+  YD+ AR   ELS  K  ++    K    GWWRG+  
Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832

Query: 820 GKRHHWFPANYVLEIE 835
           G R  WFP+ YV E E
Sbjct: 833 G-RVGWFPSTYVEEDE 847



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%)

Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           VP+   +  + W+ G +   + E E + R ++     T+LVR      G+Y +S     +
Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651
             H  IK+    G   F++ ++  F SL  L+ +Y+ H L+   +    TL+ P  +P  
Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771

Query: 652 HEGK 655
             G+
Sbjct: 772 SAGQ 775


>UniRef50_A4RIZ5 Cluster: Putative uncharacterized protein; n=2;
            Sordariomycetes|Rep: Putative uncharacterized protein -
            Magnaporthe grisea (Rice blast fungus) (Pyricularia
            grisea)
          Length = 636

 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 84/265 (31%), Positives = 127/265 (47%), Gaps = 33/265 (12%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I   +S + +Y R V+F     + +  + N + S  E  A     ++   FF +++   
Sbjct: 366  KITPRLSRMGVYTRGVSFK-SLSQAEATMPNHIFSLSEKVAFDTQRREPGAFF-EHNRNY 423

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L R+YP G R DSSN++PV FW  G+Q+VALN+Q+ D  M +N G F   G  G+++KP 
Sbjct: 424  LMRLYPHGMRFDSSNFDPVIFWRAGAQVVALNWQSWDSGMMLNEGMFA--GSDGYVVKP- 480

Query: 1053 FMFEEGYNPCDKKSIEGKVKPV-TVMLRVIGARHL-CKTGRGTAS---PFVEV------- 1100
                EGY   D K    + + +  V + V+  ++L    G+G AS   P+V+V       
Sbjct: 481  ----EGYRSSDSKDRALQSRTLDKVSITVLAGQNLPLLGGKGDASSFIPYVKVGLHTEPD 536

Query: 1101 ---EIIGADYDS-GVKLV---TKTVSDNGLNP-LWNDICEF---EVANPELALIRFVVQD 1149
                ++G D     V+ V     T+   G +P    DI EF   E   PEL  + FVV +
Sbjct: 537  PLAAMVGEDATPLDVRQVGYSGTTIKSTGTSPDFGGDIIEFLNVEGVVPELTFLSFVVMN 596

Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYR 1174
             D+ G       A   L  LR GYR
Sbjct: 597  -DVVGPDVVAAWACIRLDRLRAGYR 620



 Score = 82.2 bits (194), Expect = 8e-14
 Identities = 35/54 (64%), Positives = 44/54 (81%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
           QD++ PLS Y+ISSSHNTYLTG+Q SS+SS++AY   L  GCRCIE+D WDG +
Sbjct: 103 QDLSLPLSDYFISSSHNTYLTGNQLSSDSSVDAYKDVLLRGCRCIEIDVWDGEE 156



 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 36/81 (44%), Positives = 52/81 (64%), Gaps = 1/81 (1%)

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
           G P + HG TLT ++ F DV R +KE+AF  S+ PLI+S+E +CS  QQ  M    ++ +
Sbjct: 229 GEPRVLHGFTLTKEVLFRDVCRVVKEYAFAVSDLPLIVSLEVHCSPLQQNAMCDIMEEAW 288

Query: 423 GDLLLVHPMDKNETSLPSPHD 443
            + LL  P +++ TSLPSP D
Sbjct: 289 EEFLLPTP-EEDPTSLPSPAD 308


>UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452;
           n=1; Danio rerio|Rep: hypothetical protein LOC550452 -
           Danio rerio
          Length = 250

 Score = 91.5 bits (217), Expect = 1e-16
 Identities = 66/198 (33%), Positives = 98/198 (49%), Gaps = 25/198 (12%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV-KQEGRLYT 715
           WF    +R  AEE L      GAFL+R S+   G F+IS R + +++H +V K +   Y 
Sbjct: 58  WFKESASRGSAEETLMSREV-GAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYY 116

Query: 716 IGTVKFESLIELVSYYENHPLYK------KVKLWYPISEETVR-------------RLVS 756
           + T KF SL +LV +Y+   + K      ++KL     +E+ R              L++
Sbjct: 117 LWTEKFTSLNKLVDFYKTTSISKQKEIFLRLKLSSLSDKESARSSASPRWWLWQSTNLIT 176

Query: 757 EPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816
           +P  N     P  + P    S + V+A+YD+ A +DDEL F    II  +D+ D  WW+G
Sbjct: 177 KPQHNRSNSQP-KVKPN--RSTIQVRAIYDFTAEEDDELGFNSGDIIEVLDRSDASWWKG 233

Query: 817 DYGGKRHHWFPANYVLEI 834
              G R   FPANY  +I
Sbjct: 234 RLRG-RSGLFPANYTEQI 250


>UniRef50_Q4N7P5 Cluster: Phospholipase C, putative; n=2;
           Theileria|Rep: Phospholipase C, putative - Theileria
           parva
          Length = 974

 Score = 90.6 bits (215), Expect = 2e-16
 Identities = 57/150 (38%), Positives = 77/150 (51%), Gaps = 5/150 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLE 340
           + TL  F   L S  N I   Q  D++   ++  L  +WISSSHNTYL GDQ    ++  
Sbjct: 438 FLTLLGFNWSLTSNFNDICIPQDSDEIFSVLSLTLRDFWISSSHNTYLIGDQLGGSATAG 497

Query: 341 AYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT---LTTKIRFMDVLRTIKEHAFITSEYP 397
           A    L  GCRCIELDC DG +  P + H      LT  +   + L  IKE AF +++ P
Sbjct: 498 ALAEALLRGCRCIELDCQDGAE-EPVLCHAWKNCHLTGSVTLREGLIAIKESAFESNKLP 556

Query: 398 LILSIEDNCSLPQQRRMASAFQDVFGDLLL 427
           +ILS E +CS   + +       + GD LL
Sbjct: 557 VILSFEMHCSDEFKFQSFELVTQILGDELL 586



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 7/110 (6%)

Query: 1091 RGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI---CEFEVANPELALIRFVV 1147
            R    PFVEV ++G D ++     TK V+ N  NP+W+D      F++ NP  A++ F V
Sbjct: 863  RQKVCPFVEVSVVGEDENT---CKTKPVNFNTFNPVWSDSNPPFTFKIRNPNEAILLFYV 919

Query: 1148 QDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            +  D       +GQA FP+  LR G R V L ++   E++ S L+VH+ +
Sbjct: 920  KHYDSISS-EVLGQAAFPVNRLRPGIRWVQLLDSKFMEIDCSGLLVHIEM 968



 Score = 50.4 bits (115), Expect = 3e-04
 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 952  IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011
            ++  +I+    N + +  ETK  ++   +E +           R+YP   R+ S+N+ PV
Sbjct: 644  VDEKKIETLKRNSVFAISETKFIKI--SKEPSLLNALAERCFVRVYPSATRLASTNFCPV 701

Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044
              W+ G Q  ALN+Q+ D+ M +N G+F  + G
Sbjct: 702  KPWSHGVQFAALNFQSFDRSMLINYGRFYHSFG 734


>UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor
           type 11; n=73; Bilateria|Rep: Tyrosine-protein
           phosphatase non-receptor type 11 - Homo sapiens (Human)
          Length = 597

 Score = 89.0 bits (211), Expect = 7e-16
 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  + G   EAE+LL       DG+FL R S +  GD+ LS  R G V H +I   Q 
Sbjct: 6   WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F +L  L+ +Y  H  + +E    +I LK P+   +    + WFH H
Sbjct: 59  TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711
            +  +AE+LL +    G+FLVR S+   G F +S RT          + ++ H  ++ + 
Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176

Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736
             Y + G  +F+SL +LV +Y+ +P+
Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202



 Score = 70.5 bits (165), Expect = 3e-10
 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH + T  +AE LL     DG+FL RPS+   G F +S R    + H +++  G  Y
Sbjct: 4   RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            + G  KF +L ELV YY E+H   K+     ++L YP++
Sbjct: 64  DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591
           +E WFHG L+G  +EAE LL        G+FLVRES +  GD+ LS             +
Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164

Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            KV H  I+ ++     K+ +     FDSL +L+ HY+ +P+  +   ++ LK+P+
Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216


>UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;
           n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase
           corkscrew - Drosophila melanogaster (Fruit fly)
          Length = 845

 Score = 88.6 bits (210), Expect = 9e-16
 Identities = 62/197 (31%), Positives = 105/197 (53%), Gaps = 16/197 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  ++G   EAE LL+      DG+FL R S +  G + LS  R  +V H +I   Q 
Sbjct: 6   WFHPTISGI--EAEKLLQEQGF--DGSFLARLSSSNPGAFTLSVRRGNEVTHIKI---QN 58

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSH-PLRSQEF-LITLKEPV--PQPNKHEGKEWFHA 660
            G   F L     F +L  L+ +Y  +  L+ +    I LK+P+   +P     + WFH 
Sbjct: 59  NG-DFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLICAEPTT---ERWFHG 114

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI-GTV 719
           + +  +AE+L+ +   +G+FLVR S+ + G F +S RT+ ++ H  ++ + + Y + G  
Sbjct: 115 NLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDVGGGE 174

Query: 720 KFESLIELVSYYENHPL 736
            F +L EL+ +Y+ +P+
Sbjct: 175 SFGTLSELIDHYKRNPM 191



 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           + WFH   +  +AE+LL++   DG+FL R S    G+F +S R   E+ H +++  G  +
Sbjct: 4   RRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFF 63

Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK 739
            + G  KF +L ELV YY EN  L +K
Sbjct: 64  DLYGGEKFATLPELVQYYMENGELKEK 90



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 8/91 (8%)

Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602
           E WFHG L+G  +EAE L+       +G+FLVRES +  GD+ LS     KV H  I+ +
Sbjct: 109 ERWFHGNLSG--KEAEKLILERGK--NGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQ 164

Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
            +    K+ +     F +L  LI HY+ +P+
Sbjct: 165 DK----KYDVGGGESFGTLSELIDHYKRNPM 191


>UniRef50_Q2H4G2 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 693

 Score = 86.2 bits (204), Expect = 5e-15
 Identities = 42/81 (51%), Positives = 57/81 (70%), Gaps = 3/81 (3%)

Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQ--DMTRPLSHYWISSSHNTYLTGDQFSSESSL 339
           Y+   EF   L+S+  S + +  ++  Q  D TRP+S+Y+ISSSHNTYL G+Q SS+SS 
Sbjct: 114 YYRFDEFF-WLWSQTESAWRAAGEQQQQEVDATRPISNYFISSSHNTYLEGNQLSSKSSA 172

Query: 340 EAYVRCLRSGCRCIELDCWDG 360
           EAY   LR+GCRCIE+D W+G
Sbjct: 173 EAYRAALRNGCRCIEIDVWNG 193



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 3/125 (2%)

Query: 934  IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTF-FVKYHTTQ 992
            I + +S+L IY  S  +  +         + + S  E   E L          +K++   
Sbjct: 401  ICRALSELAIYTHSQHYTDDSSLDTCQAPSHIFSLSEDSFEALTEDHNKLQKMLKHNRDF 460

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
              RIYPKG R+DSSN +P   W  G QMVA+N+Q  D+ M +N   F   G  G+ILKP 
Sbjct: 461  FMRIYPKGLRVDSSNPDPSFHWRRGVQMVAMNWQKSDEGMLINDAMFA--GTNGWILKPP 518

Query: 1053 FMFEE 1057
             +  +
Sbjct: 519  ALLSD 523



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 21/63 (33%), Positives = 35/63 (55%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P ++H  T+T+ + F +V R I+E AF  +  P+I+S+E      QQ  M    ++ +  
Sbjct: 283 PVVHHHGTMTSTVGFREVCRAIRESAFEKNPLPIIISLEVGADWEQQEVMVKIMKEEWNG 342

Query: 425 LLL 427
           LLL
Sbjct: 343 LLL 345


>UniRef50_Q9STZ3 Cluster: 1-phosphatidylinositol-4, 5-bisphosphate
            phosphodiesterase; n=4; Arabidopsis thaliana|Rep:
            1-phosphatidylinositol-4, 5-bisphosphate
            phosphodiesterase - Arabidopsis thaliana (Mouse-ear
            cress)
          Length = 531

 Score = 85.4 bits (202), Expect = 8e-15
 Identities = 53/201 (26%), Positives = 94/201 (46%), Gaps = 7/201 (3%)

Query: 983  TFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQN 1042
            T  + +   +  R  P+ + +  + Y P   W  G+Q++AL+ +   + + +  G F+ N
Sbjct: 313  TDIISFTQKRFLRTRPQRKLLIYAPYKPQRAWMHGAQLIALSRKEEKEKLWLMQGMFRAN 372

Query: 1043 GGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLC----KTGR-GTASPF 1097
            GGCG++ KP F+   G +     ++   V  +  +   +G   +     + GR      +
Sbjct: 373  GGCGYVKKPDFLLNAGPSGVFYPTVNPVVVKILKVKIYMGDGWIVDFKKRIGRLSKPDLY 432

Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157
            V + I G  +D  +  +  TV +N   P W +   F +  P+LALI F V D ++     
Sbjct: 433  VRISIAGVPHDENI--MKTTVKNNEWTPTWGEEFTFPLTYPDLALISFEVYDYEVSTADA 490

Query: 1158 FIGQATFPLLCLRKGYRSVPL 1178
            F GQ   P+  L +G R+VPL
Sbjct: 491  FCGQTCLPVSELIEGIRAVPL 511



 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 46/137 (33%), Positives = 65/137 (47%), Gaps = 2/137 (1%)

Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT 364
           D+V  DM  PLSHY+I +S N+Y TG+ F   S L   +  L  G R +ELD W    G+
Sbjct: 101 DQVHHDMHAPLSHYFIHTSLNSYFTGNVFGKYSILPI-IEALEQGVRVVELDLWPDGRGS 159

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
             +         ++  + L +IKEHAF    YPLI++ +D      Q +     Q  F  
Sbjct: 160 ICVRPSWNFEKPLKLQECLDSIKEHAFTKCTYPLIITFKDGLKPELQSKATQMIQQTFNH 219

Query: 425 LLLVHPMDKNETSLPSP 441
           ++  H     E   PSP
Sbjct: 220 MVYHHDPHSLEV-FPSP 235


>UniRef50_Q7SE08 Cluster: Putative uncharacterized protein
           NCU02175.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU02175.1 - Neurospora crassa
          Length = 598

 Score = 85.0 bits (201), Expect = 1e-14
 Identities = 45/95 (47%), Positives = 61/95 (64%), Gaps = 8/95 (8%)

Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSIYDS--QYDKVTQDMTRPLSHYWISSSHNTYLTGD 331
           P +D+Y    T  EF    +S   + +++    D    D+T P+S+Y+ISSSHNTYL G+
Sbjct: 102 PVKDVY----TFEEFF-WAWSSNKAAWNAVRPLDPTEIDLTYPISNYFISSSHNTYLEGN 156

Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGTP 365
           Q SS+SS EAY   LR+GCRCIE+D W+G P  TP
Sbjct: 157 QLSSKSSAEAYKAVLRNGCRCIEIDVWNGAPSRTP 191



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 44/119 (36%), Positives = 60/119 (50%), Gaps = 4/119 (3%)

Query: 934  IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ- 992
            I + ++ L IY RS  FN +   +     + + S  E K   ++SQ E    +  H  Q 
Sbjct: 384  ICEMLAALAIYTRSEHFN-DVNSLASTTPSHIFSVNEDKFIDMISQDEALSKIMDHNRQY 442

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
              RIYPKG R DSSN +P   W  G QMVA+N+Q  D+   +N   F      G+ILKP
Sbjct: 443  FMRIYPKGLRFDSSNPDPTIPWRRGVQMVAMNWQNTDEGTMLNDAMFADTN--GWILKP 499



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 24/79 (30%), Positives = 42/79 (53%)

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
           G P ++H  T+TT + F +V + ++E AF+T+  P+I+S+E      QQ  M    ++ +
Sbjct: 263 GEPIVHHHGTMTTTVPFREVCKAVREEAFVTNHLPIIVSLEVGADREQQEMMVEIMKEEW 322

Query: 423 GDLLLVHPMDKNETSLPSP 441
             LLL  P +  +     P
Sbjct: 323 AGLLLEEPFENCDRLTQQP 341


>UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;
           n=26; Euteleostomi|Rep: Growth factor receptor-bound
           protein 2 - Homo sapiens (Human)
          Length = 217

 Score = 83.4 bits (197), Expect = 3e-14
 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL ELV Y+ +  + +  +++       +R +   P        P Y      
Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
                V+AL+D+  ++D EL F +   I  +D  D  WW+G   G+    FP NYV  +
Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E VPQ
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>UniRef50_Q2H674 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 1065

 Score = 82.6 bits (195), Expect = 6e-14
 Identities = 48/112 (42%), Positives = 65/112 (58%), Gaps = 6/112 (5%)

Query: 257 GDDEVQASQFIRDYLRDPQRDI-YEPYFTLS-----EFVEMLYSKQNSIYDSQYDKVTQD 310
           G D++ + +    +L+D QRD   E    LS     +    L    +SI  +      +D
Sbjct: 50  GADKLWSPEKAAAFLKDTQRDTDAERALELSTGKPWDLNAFLRYMTSSITHAISPPHEED 109

Query: 311 MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362
           ++ PLS Y+ISSSHNTYLTG+Q SS+SS +AY   L  GCRCIE+D WDG D
Sbjct: 110 LSWPLSSYFISSSHNTYLTGNQLSSDSSADAYKNVLLRGCRCIEVDVWDGDD 161



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 4/126 (3%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            K ++  +I + +S L IY R V+F     + +  +   + S  E     +  +     F 
Sbjct: 382  KSKKPSKIIQALSKLGIYTRGVSFKSLE-QAEATMPTHIFSLSEKGVVEVHQKSAYELF- 439

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +++   L R YP G RI SSN +P  FW  G Q+VALN+Q  D+ M +N G F   G  G
Sbjct: 440  EHNRRYLMRTYPSGLRIRSSNLDPAVFWRKGIQIVALNWQNWDEGMMLNEGMFA--GTNG 497

Query: 1047 FILKPQ 1052
            ++LKP+
Sbjct: 498  YVLKPE 503



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HG+TLT ++ F +V   I+++AF  ++ PLI S+E +CS  QQ  M +   + +G 
Sbjct: 269 PRVLHGYTLTKEVSFREVCVAIRDYAFAVTDTPLIASLEVHCSAEQQETMVAIMLETWGP 328

Query: 425 LLLVHPMDKNETSLPSP 441
            LL  P + +   LPSP
Sbjct: 329 FLLPEPKE-DAAHLPSP 344


>UniRef50_UPI0000F1F414 Cluster: PREDICTED: hypothetical protein; n=1;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 872

 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%)

Query: 929  ERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKY 988
            +R  +++ E+SDL++Y  SV F       K    NEMSSF E+ A +L+ ++    FV++
Sbjct: 71   KRDCKLSSELSDLVVYTSSVAFKQFDPSAKK-APNEMSSFSESDALKLI-KESGKLFVRH 128

Query: 989  HTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQM 1020
            ++ QLSRIYP GQR+ SSNYNP   WN G Q+
Sbjct: 129  NSVQLSRIYPSGQRVQSSNYNPQDMWNAGCQI 160



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 33/76 (43%), Positives = 45/76 (59%)

Query: 1122 GLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNA 1181
            G NP W+   +F++  PEL LIRF+V+D D     +F+GQ T P   LR GYR V L NA
Sbjct: 161  GFNPRWDCTFKFQLHVPELVLIRFMVEDHDYTTRNDFLGQFTLPFPSLRTGYRHVRLLNA 220

Query: 1182 FSEELELSTLMVHLSI 1197
                +  S+L +H+ I
Sbjct: 221  DGCSISPSSLFIHVKI 236


>UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor
           receptor-bound protein 2; n=1; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Growth factor
           receptor-bound protein 2 - Strongylocentrotus purpuratus
          Length = 176

 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 60/182 (32%), Positives = 89/182 (48%), Gaps = 27/182 (14%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE-GRLYT 715
           WF    TR  AE LL +   +GAFLVR SE  +G +++S +  + ++H R+ Q+    + 
Sbjct: 14  WFFPTITRKNAELLLMQER-NGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAGKFH 72

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +  VKF SL  LV YY    + ++ +    +S ++V +    P                 
Sbjct: 73  LWIVKFPSLDALVDYYRTTSVTRENQ----VSTQSVEQWSRNPQ---------------- 112

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                ++ALYD+   ++ EL F K  IIT +DKP + WWRG   G R    PA YV E E
Sbjct: 113 ----RLQALYDFDPEEEGELCFRKGDIITLIDKPTKDWWRGTVDG-RTGMLPAPYVKEEE 167

Query: 836 VP 837
            P
Sbjct: 168 EP 169


>UniRef50_A4RFY5 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 602

 Score = 81.4 bits (192), Expect = 1e-13
 Identities = 51/145 (35%), Positives = 71/145 (48%), Gaps = 23/145 (15%)

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD--GTPFI 367
           D + PL  Y++SSSHNTYL   Q    S   AY   LR+G RC+E+D WD  D    P +
Sbjct: 104 DRSHPLPEYFVSSSHNTYLVAHQLYGTSCATAYRTALRTGSRCVEIDAWDNGDNRSEPKV 163

Query: 368 YHGHTLTTKIRFMDVLRTIK----EHAFITSEY-----------------PLILSIEDNC 406
            HG+TL + I F  V  TI+    E A    +                  P++LS+E++C
Sbjct: 164 THGYTLVSNIPFRLVCETIRDVVDEEAAQAQKLPVGADAAEREDERYRPAPILLSLENHC 223

Query: 407 SLPQQRRMASAFQDVFGDLLLVHPM 431
               Q R+    ++VFG  LL  P+
Sbjct: 224 DAAGQLRLVEIMREVFGHRLLDKPV 248



 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%)

Query: 989  HTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047
            H  Q L R+YPKG RI S N   +PFW  G+Q+ A+N+QT    MQ+N   F   G  G+
Sbjct: 383  HNAQHLMRVYPKGTRISSRNMKVIPFWAVGAQICAMNWQTFGANMQMNEALFA--GTDGY 440

Query: 1048 ILKPQFMFEEG 1058
            +LKPQ +   G
Sbjct: 441  VLKPQALRSGG 451


>UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21;
           Bilateria|Rep: GRB2-related adapter protein - Homo
           sapiens (Human)
          Length = 217

 Score = 80.6 bits (190), Expect = 2e-13
 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           W+    +R  AEE+L K N  GAFL+R SE   G F++S     +++H +V +E    Y 
Sbjct: 60  WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775
           +   KF SL ELV +Y    + KK             R +   D+  +  +PG       
Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
                 +A +D+ A+   +LSF +  II  +++PD  WWRG   G R  +FP +YV  + 
Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216

Query: 836 V 836
           +
Sbjct: 217 L 217



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+ G+++  RQ AE++L    HLG   FL+RES +  G++ +S     +V H ++ L++ 
Sbjct: 60  WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646
            G  K++L +   F+SL  L+  YR+  + + ++  +  +EP+
Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154


>UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:
           ENSANGP00000020137 - Anopheles gambiae str. PEST
          Length = 185

 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 55/177 (31%), Positives = 89/177 (50%), Gaps = 30/177 (16%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +W++   TR  AE+LL   + +GAFL+R SE   G F++S +    ++H +V ++ +  +
Sbjct: 33  DWYYGRITRADAEKLLSNKH-EGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKF 91

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTS 774
            +  VKF SL ELV Y+    + +         +  +R +V E                 
Sbjct: 92  FLWVVKFNSLNELVDYHRTASVSRS-------QDVKLRDMVPE----------------- 127

Query: 775 FTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
              ++ V+ALYD+ A++  EL F +  +IT  D+ DE WW G+  G R   FPA YV
Sbjct: 128 ---EMLVQALYDFVAQESGELDFRRGDVITVTDRSDEHWWNGEI-GNRKGLFPAIYV 180



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 35/105 (33%), Positives = 63/105 (60%), Gaps = 12/105 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G++   R +AE LL ++ H  +G FL+R S +  GD+ LS      V H ++ L+  
Sbjct: 34  WYYGRIT--RADAEKLL-SNKH--EGAFLIRISESSPGDFSLSVKCSDGVQHFKV-LRDA 87

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648
           +G  KF+L   + F+SL  L+ ++R+  + RSQ+  + L++ VP+
Sbjct: 88  QG--KFFLW-VVKFNSLNELVDYHRTASVSRSQD--VKLRDMVPE 127


>UniRef50_Q86YU7 Cluster: FLJ00417 protein; n=4; Tetrapoda|Rep:
            FLJ00417 protein - Homo sapiens (Human)
          Length = 600

 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 44/106 (41%), Positives = 61/106 (57%), Gaps = 7/106 (6%)

Query: 1092 GTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDED 1151
            G+  PFVEVEIIG   D   +  T+ V DNG NP W +   F V  PE+AL+RF+V D D
Sbjct: 172  GSFDPFVEVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHD 230

Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
              G  +FIGQ T     +  GYR V     + E +E +++ VH+++
Sbjct: 231  PIGR-DFIGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 270


>UniRef50_Q5IRA3 Cluster: Phosphatidyl inositol-specific
           phospholipase C; n=15; Sordariomycetidae|Rep:
           Phosphatidyl inositol-specific phospholipase C -
           Cryphonectria parasitica (Chesnut blight fungus)
           (Endothiaparasitica)
          Length = 736

 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 36/77 (46%), Positives = 50/77 (64%)

Query: 286 SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
           ++F+  + S   S       +   D++ PLS Y+ISSSHNTYLTG+Q SS++S +AY   
Sbjct: 106 NDFLRYMTSDATSAVTPLNAQTGGDLSYPLSSYFISSSHNTYLTGNQLSSDASTDAYKNV 165

Query: 346 LRSGCRCIELDCWDGPD 362
           L  GCRCIE+D WDG +
Sbjct: 166 LLRGCRCIEIDVWDGDE 182



 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 50/180 (27%), Positives = 96/180 (53%), Gaps = 10/180 (5%)

Query: 927  KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986
            K ++  +I   +S L IY ++V+F     + +  + + + S  E     +  +Q    F 
Sbjct: 427  KKKKPSKIIHALSALGIYTKAVSFKSLH-QPEATMPSHVFSLGEKSVREVHEKQGQDLF- 484

Query: 987  KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046
            +++   L R YP G R+ SSN +P PFW  G Q+ ALN+Q  D+ M +N G F  +G  G
Sbjct: 485  EHNRKYLMRAYPSGFRVGSSNLDPTPFWRKGIQIAALNWQHWDEGMMLNEGMFAGSG--G 542

Query: 1047 FILKPQ-FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGTASPFVEVEI 1102
            ++LKP  +  ++   P +   ++ +   + + ++V+ A++L    +T   + +P+V+VE+
Sbjct: 543  YVLKPPGYRHDKPNAPAETAHVQHRT--LDLEIKVLAAQNLPLPPETSVKSFNPYVKVEL 600



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 1/106 (0%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HG+TLT ++ F +V   IKE+AF  ++ PLI+S+E +    QQ  M     + +  
Sbjct: 306 PRVLHGYTLTKEVSFREVCLAIKEYAFAVTDLPLIVSLEVHAGPEQQEIMVKIMNETWAG 365

Query: 425 LLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEE 470
           LLL  P +K    LPSP D            P G E S+ A   E+
Sbjct: 366 LLL-DPPEKEADVLPSPSDLRRKILVKVKYAPPGQEVSAAAASDED 410


>UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep:
           Protein vav-2 - Homo sapiens (Human)
          Length = 878

 Score = 79.8 bits (188), Expect = 4e-13
 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%)

Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698
           + P+ +P   E       WF  +  R Q + LL K++  G +L+R    E   FAIS + 
Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713

Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750
             E+KH + V+++  ++     KF+SL+ELV YY+ H L +  K     L YP    E +
Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773

Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793
             R  S    +       ++ P               + FT +V  T  A Y++ AR   
Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833

Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833
           ELS  +  ++    +   D+GWW+G+  G R  WFP+ YV E
Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%)

Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P  E+ + A  WF G +   RQ+ ++LL++HA    GT+L+RE       + +S     +
Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645
           V H ++  K        ++ ++  FDSL  L+ +Y+ H L+   ++   TLK P
Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766


>UniRef50_Q0UVV5 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 617

 Score = 79.4 bits (187), Expect = 5e-13
 Identities = 33/51 (64%), Positives = 41/51 (80%)

Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360
           D + P+S+Y+ISSSHNTYLTG+Q SSESS +AY   L  GCRC+E+D WDG
Sbjct: 115 DESYPISNYFISSSHNTYLTGNQLSSESSTDAYKNVLMRGCRCVEIDVWDG 165



 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 29/58 (50%), Positives = 36/58 (62%), Gaps = 2/58 (3%)

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            R YPKG R++SSN NP  FW  G Q+VALN+Q  D  M  N   F   G  G++LKP+
Sbjct: 451  RAYPKGLRLNSSNLNPSVFWRAGVQIVALNWQRWDGGMMQNEAMFA--GTPGWVLKPE 506



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 27/73 (36%), Positives = 42/73 (57%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HG+TLT  + F  V  TI+++AF TS  PLI+S+E +    QQ  M     + +  
Sbjct: 244 PRVLHGYTLTKDLPFRAVCATIRDYAFKTSNLPLIVSLEVHTCPEQQEIMVELMNEYWKG 303

Query: 425 LLLVHPMDKNETS 437
           LL+  P+D ++ S
Sbjct: 304 LLVDLPIDPSQPS 316


>UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3
           adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to SH2/SH3 adaptor Grb2 -
           Strongylocentrotus purpuratus
          Length = 241

 Score = 79.0 bits (186), Expect = 7e-13
 Identities = 53/188 (28%), Positives = 95/188 (50%), Gaps = 16/188 (8%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEK--EQGSFAISFRTEKEIKHCRVKQE-GRL 713
           W+    +R  AEE L    +DGAF++R SE   + G+F++S +   +++H ++  +    
Sbjct: 62  WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKILTDLAGK 121

Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPT 773
           Y +  VKF S+ +LV Y++++ + +  ++   ++E  V       +D      P      
Sbjct: 122 YFLWVVKFTSINDLVDYHKDNSVSRTQEI--VLNEPCV-----PIEDANQRPQPAMQQSR 174

Query: 774 SFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDY---GGKRHHWFPANY 830
               +  VKALY++ +    EL+F ++ +IT   +P   WW G+     G R   FP NY
Sbjct: 175 ERLQQ--VKALYNFESDDAQELTFKQNDVITLTGRPHADWWEGEIRAPTGTRRGIFPKNY 232

Query: 831 VLEIEVPH 838
           V E++ PH
Sbjct: 233 VKELD-PH 239


>UniRef50_UPI000023D8AD Cluster: hypothetical protein FG06693.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG06693.1 - Gibberella zeae PH-1
          Length = 633

 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 34/57 (59%), Positives = 42/57 (73%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365
           QD+T PL+ Y+ISSSHNTYLTG+Q SS+SS + Y   L  G RCIE+D WDG +  P
Sbjct: 97  QDLTYPLASYFISSSHNTYLTGNQLSSDSSTKPYTETLLRGGRCIEIDVWDGDESEP 153



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 79/273 (28%), Positives = 122/273 (44%), Gaps = 40/273 (14%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            ++ +E+S +  +CR V+F        G     + S  E K   +  +Q +  F  ++   
Sbjct: 353  KVIQELSKMGFHCRGVSFKSLSQPEAGMP-THIFSLSEKKVIDVHEEQADALF-NHNRHF 410

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            L R YP G RI SSN +P  FW  G Q+VALN+Q  D+ M +N G F   G  G++LKP 
Sbjct: 411  LMRTYPWGLRIGSSNLDPSVFWRKGIQVVALNWQRWDEGMMLNEGMFAGTG--GYVLKPL 468

Query: 1053 FMFEEGYNPCDKKSIEGKVKP---VTVMLRVIGARHL-----CKTGRGTASPFVEVEI-- 1102
                 GY P     +     P   + + + VI A+++      K+ RG   P+V+VE+  
Sbjct: 469  -----GYRPNRNDEVVSNTIPRQTLHLTITVIAAQNIPLPPGDKSARG-FEPYVKVELHV 522

Query: 1103 -------------IGADYDSGVKLVTKT----VSDNGLNPLWNDICEFEVANPELALIRF 1145
                          G + +   K  T+T    V D G  PL  +         EL+ +RF
Sbjct: 523  EGPDEFHGGPIPNDGHEREGEYKARTRTQKGDVVDFGSEPL--EFPPIPHVVDELSWVRF 580

Query: 1146 VVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
             ++D++I G  +    A   +  L  GYR V L
Sbjct: 581  TIRDDEI-GRDDMAAWACMRVDRLGHGYRFVHL 612



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 1/79 (1%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HG+TLT +I F  V   I++ AF+ S+ P+I+S+E +C+  QQ  M    + V+  
Sbjct: 230 PRVLHGYTLTKEISFRAVCEAIRDSAFVVSDLPVIVSLEVHCNAEQQLAMVRIMKQVWEG 289

Query: 425 LLLVHPMDKNETSLPSPHD 443
           LL+  P + +  +LPSP +
Sbjct: 290 LLVAEP-ENDPENLPSPDE 307


>UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9;
           Endopterygota|Rep: CG3727-PB, isoform B - Drosophila
           melanogaster (Fruit fly)
          Length = 548

 Score = 78.2 bits (184), Expect = 1e-12
 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%)

Query: 644 EPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIK 703
           +P+ +PN   GK W++   TR+Q + +L     DG FL+R SE   G +++S +     K
Sbjct: 436 QPIERPNL-AGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNK 494

Query: 704 HCRVKQEGRLYTIGTVKFESLIELVSYYENHPLY 737
           H RV  E  +Y IG  KF SL +LV +Y+  P+Y
Sbjct: 495 HFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIY 528



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 9/89 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R + + +L  H H  DG FL+R+S T +GDY +S    G+  H R+ ++Q 
Sbjct: 448 WYYGAIT--RSQCDTVLNGHGH--DGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQ- 502

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
                 Y I    F SL  L+ HY+  P+
Sbjct: 503 ----NMYCIGQRKFHSLDQLVDHYQRAPI 527



 Score = 55.6 bits (128), Expect = 8e-06
 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 771 DPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830
           DP        VK  Y+Y+A+Q DELS  K   I  ++K ++GWWRG   G    WFP+NY
Sbjct: 249 DPAEAIGTAVVK--YNYQAQQPDELSLTKGTRILILEKSNDGWWRGQ-SGNSVGWFPSNY 305

Query: 831 VLE 833
             E
Sbjct: 306 TTE 308


>UniRef50_A6RBI2 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 660

 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 33/57 (57%), Positives = 44/57 (77%), Gaps = 1/57 (1%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGT 364
           QD++ P+++Y+ISSSHNTYLTG+Q  SESS + Y   L  GCRC+E+D WDG PD +
Sbjct: 82  QDLSLPMNNYFISSSHNTYLTGNQLYSESSTKVYRDVLLKGCRCLEIDVWDGEPDSS 138



 Score = 66.1 bits (154), Expect = 5e-09
 Identities = 28/68 (41%), Positives = 44/68 (64%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P ++HG+TLT +I F DV  TI++HAF+TS+ P+I+S+E +  L QQ+ M       +  
Sbjct: 224 PLVFHGYTLTKEITFRDVCNTIRDHAFVTSDLPIIVSLEVHACLEQQKVMVDIITQAWEG 283

Query: 425 LLLVHPMD 432
           +L+  P D
Sbjct: 284 MLIELPAD 291



 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 4/120 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I   +S L IY R  TF+ +  + +    N + S  E+        +    F +++   
Sbjct: 373  KILHSLSRLGIYTRGHTFS-KFSQQEATQPNHIFSLSESAVRDAYENERQALF-EHNREY 430

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            + R YP G R++SSN +P  +W  G Q+VALN+Q  DK M +N G F   G  G++LKP+
Sbjct: 431  MMRTYPSGLRVNSSNLDPSFYWRRGIQIVALNWQNCDKGMMMNEGMFV--GYRGWVLKPE 488


>UniRef50_A2QEJ2 Cluster: Catalytic activity:
           1-phosphatidyl-1D-myo-inositol 4; n=1; Aspergillus
           niger|Rep: Catalytic activity:
           1-phosphatidyl-1D-myo-inositol 4 - Aspergillus niger
          Length = 594

 Score = 77.0 bits (181), Expect = 3e-12
 Identities = 49/135 (36%), Positives = 71/135 (52%), Gaps = 13/135 (9%)

Query: 234 SNGTTITLREFQNFLR--DEQHDNLGDDEVQASQFIRDYLRDPQ------RDIYEPYFTL 285
           SN   ITL    + L   D+ + +L    +    F+ D  R+P+      ++   P  TL
Sbjct: 6   SNAQKITLPFAPSMLNYIDKIYSSL--TSMNQPNFLTDVQREPKGQGSTTKEHPAPLATL 63

Query: 286 SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345
           + F E L S + S   +       D++ P++ Y+IS+SHNTYLTG+Q  SES   AY   
Sbjct: 64  AAFYEYLASPEASAMRAA---TQMDLSAPITDYFISTSHNTYLTGNQLYSESKASAYTNV 120

Query: 346 LRSGCRCIELDCWDG 360
           L SGCR +E+D WDG
Sbjct: 121 LLSGCRSVEIDVWDG 135



 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 81/287 (28%), Positives = 130/287 (45%), Gaps = 37/287 (12%)

Query: 933  RIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991
            +I + +S L ++ +   F N  +   K  V + + S  E KA R     +     +++  
Sbjct: 318  KILQALSKLAVFTKGFHFSNFAQPEAK--VPSHVFSLSE-KAVREAHATDGDALFEHNRH 374

Query: 992  QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051
               R+YP G R+DSSN +P  FW  G+QMVALN+Q  DK M +N G F   G  G++LKP
Sbjct: 375  FFMRVYPNGLRVDSSNMDPTFFWRRGAQMVALNWQNFDKAMMLNAGMFA--GEQGWVLKP 432

Query: 1052 QFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL----CKTGRGTASPFV----EVE-- 1101
                  GY   D +    + + + + +  +  +++      T      PFV     VE  
Sbjct: 433  -----PGYRSSDAQPGIIEPRRLDLTIEFLAGQNIPLPPGHTNENKFYPFVTCLLHVETP 487

Query: 1102 ---IIGADYD-----SGVKLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQD 1149
                  AD D     +G K  TK+V+  G+NP       EF   +    EL  +RF ++D
Sbjct: 488  DDSFAAADDDTESEKTGYKHCTKSVT--GVNPDFGGQKMEFATVSGFLDELTFVRFKIKD 545

Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLS 1196
             + +        A   L  L++GYR + L ++     E   L+VH++
Sbjct: 546  NE-WMHNALAAWACIRLDRLQEGYRIIHLNDSTGAPTE-GALLVHIT 590



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 24/77 (31%), Positives = 44/77 (57%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HGHTLT +  F +V   I++ AF+ S+ P+I+S+E +  L QQ+ M    ++ +  
Sbjct: 171 PRVLHGHTLTRETSFREVCYAIRDSAFVASDLPVIVSLEVHTCLEQQQTMVEIMEEAWKG 230

Query: 425 LLLVHPMDKNETSLPSP 441
           +L+    +    ++P P
Sbjct: 231 MLVEVTPELEAGTVPPP 247


>UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6
           SCAF14737, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 393

 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 34/84 (40%), Positives = 51/84 (60%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           GKEW++   TR QAE  L +   +G FL+R SE     F+IS + + + KH +V+ +  L
Sbjct: 294 GKEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESL 353

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  KF S+ ELV +Y+  P++
Sbjct: 354 YCIGQRKFHSMEELVEHYKKAPIF 377



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K   +  ++K  +GWWRG Y G R  WFP+NYV E
Sbjct: 118 FSYAAEREDELSLVKGTRVVVMEKCSDGWWRGSYSG-RSGWFPSNYVTE 165



 Score = 47.6 bits (108), Expect = 0.002
 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++GK+   R +AE  L      GD  FL+R+S +   D+ +S   Q K  H +++LK+ 
Sbjct: 297 WYYGKVT--RHQAEVALNQRGVEGD--FLIRDSESSPHDFSISLKAQSKNKHFKVQLKE- 351

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
                 Y I    F S+  L+ HY+  P+ + E
Sbjct: 352 ----SLYCIGQRKFHSMEELVEHYKKAPIFTSE 380



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      +  + P+NYV
Sbjct: 2   TEEVIVIAKFDYMAQQDQELDIKKNERLWLLD-DSKSWWRVRNATNKTGFVPSNYV 56



 Score = 35.5 bits (78), Expect = 8.9
 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIE 835
           TV+ALY + +   +EL+F K  ++  V+KP  D  WW+      +    P NYV  ++
Sbjct: 206 TVQALYPFSSDNAEELNFEKGEVMEVVEKPENDPEWWKCRKADGQLGLVPKNYVTVLD 263


>UniRef50_Q5B933 Cluster: Putative uncharacterized protein; n=1;
            Emericella nidulans|Rep: Putative uncharacterized protein
            - Emericella nidulans (Aspergillus nidulans)
          Length = 614

 Score = 74.9 bits (176), Expect = 1e-11
 Identities = 77/255 (30%), Positives = 116/255 (45%), Gaps = 43/255 (16%)

Query: 958  KGFVYNEMSSFPETK--------AERLMSQQENTF---FVKYHTTQLSRIYPKGQRIDSS 1006
            KGF + + S  PE K        +ER   Q +  +     +++     R+YP G R++SS
Sbjct: 348  KGFSFKQFSQ-PEAKVPGHVFSLSERAARQADEKYGKELFEHNRKYFMRVYPYGLRVNSS 406

Query: 1007 NYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS 1066
            N +P  FW  G+Q+VALN+Q  DK M +N G F   G  G+ILKPQ     GY   + +S
Sbjct: 407  NLDPTFFWRRGAQIVALNWQNSDKGMMLNQGMFA--GEQGWILKPQ-----GYRSTEPES 459

Query: 1067 IEGKVKPVTVMLRVIGARHLC--------KTGRGTASPFVEVE---------IIGADYDS 1109
                 + V + + V+  + L         K  R   + +V VE         + G D   
Sbjct: 460  APIPRRTVDLSIEVLAGQDLTLPPGDKNEKGFRPYVACYVHVETPEDAANPGLKGDDSTD 519

Query: 1110 GVKLVTK--TVSDNGLNP-LWNDICEFEV---ANPELALIRFVVQDEDIFGEPNFIGQAT 1163
              K   K  T +  G+NP   + I +F        EL  +RF V+D++I G  +    A 
Sbjct: 520  SEKTSYKRVTKAGEGVNPDFGSQILQFPTLPGVVEELTFVRFKVKDDEI-GFDSLASWAC 578

Query: 1164 FPLLCLRKGYRSVPL 1178
              L  L++GYR + L
Sbjct: 579  IRLTRLQEGYRVLRL 593



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 33/77 (42%), Positives = 45/77 (58%), Gaps = 2/77 (2%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF-G 423
           P + HGHTLT    F +V   I++ AFI S+ P+I+S+E + SL QQ  M    +D F G
Sbjct: 202 PKVLHGHTLTKGTTFREVCYAIRDSAFIVSDLPVIVSLEVHASLEQQETMVEIMEDAFDG 261

Query: 424 DLLLVHP-MDKNETSLP 439
            L+ V P M+  ET  P
Sbjct: 262 MLIQVTPEMEAMETPPP 278



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 6/83 (7%)

Query: 262 QASQFIRDYLRDPQ--RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYW 319
           ++S F RD  RD Q  +D   P  +L+ F   + S   S   +       D + P++ Y+
Sbjct: 49  ESSNFSRDIQRDDQDPKD-NNPLSSLAAFHAYMASPSAS---ALRPAGPPDDSAPITDYF 104

Query: 320 ISSSHNTYLTGDQFSSESSLEAY 342
           ISSSHNTYLTG+Q  S+++ +AY
Sbjct: 105 ISSSHNTYLTGNQLYSDAAAKAY 127


>UniRef50_Q4WX21 Cluster: Phosphoinositide-specific phospholipase C,
            putative; n=4; Trichocomaceae|Rep:
            Phosphoinositide-specific phospholipase C, putative -
            Aspergillus fumigatus (Sartorya fumigata)
          Length = 652

 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 73/276 (26%), Positives = 128/276 (46%), Gaps = 33/276 (11%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I   +S L ++ +  +F  +  + +  V   + S  E  A    ++  +   ++++   
Sbjct: 373  KILHSLSRLAVFTKGFSFR-QFTQPEAKVPGHVFSLSENAAREAYAKDRDAL-LEHNRHF 430

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
              R+YP G R++SSN +P  FW CG+Q+VALN+Q  DK M +N G F      G++LKPQ
Sbjct: 431  FMRVYPYGLRVNSSNPDPTFFWRCGAQIVALNWQNLDKGMMLNRGMFTSEP--GWVLKPQ 488

Query: 1053 FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-------CKTG-RGTASPFVEVEI-- 1102
                 GY   D  S   K + + + + ++  ++L        ++G R   S ++ VE   
Sbjct: 489  -----GYRSSDPPSTPVKRQQLDLSIEILAGQNLPLPPGDTKESGFRPYVSCYLHVECPD 543

Query: 1103 ------IGAD--YDSGVKLVTKTV-SDNGLNPLWN-DICEFEVAN---PELALIRFVVQD 1149
                   G D   DS      +++ S  G NP +   + +F        EL  +RF V+D
Sbjct: 544  EENGFPPGGDNTTDSEKTSYKRSIKSATGRNPDFGAQMIQFPTLQGVIDELTFVRFKVKD 603

Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185
            +++ G  +    A   L  L++GYR + L +    E
Sbjct: 604  DEL-GRDSLAAWACLKLSRLQQGYRLIHLHDCSGAE 638



 Score = 74.1 bits (174), Expect = 2e-11
 Identities = 27/52 (51%), Positives = 41/52 (78%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360
           +D++ P++ Y++SSSHNTYLTG+Q  S+++  AY   L +GCRC+E+D WDG
Sbjct: 94  EDLSAPITDYYVSSSHNTYLTGNQLYSDAAAAAYTNVLLNGCRCVEIDVWDG 145



 Score = 56.0 bits (129), Expect = 6e-06
 Identities = 25/77 (32%), Positives = 42/77 (54%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HGHTLT   +F DV   I++ AF+ S+ P+I+S+E +  + QQ  M    ++ F  
Sbjct: 244 PRVLHGHTLTKGTKFRDVCYAIRDSAFVASDLPVIVSLEVHTCIEQQATMVEIMEEAFKG 303

Query: 425 LLLVHPMDKNETSLPSP 441
           +L+    +   +  P P
Sbjct: 304 MLIEVTPELEASQAPPP 320


>UniRef50_Q1E522 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 654

 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 9/106 (8%)

Query: 260 EVQASQFIRDYLRDPQRDIYEP-----YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRP 314
           E  +  F+R   +D   D+  P       TL  F+E + +       ++ D    D++ P
Sbjct: 49  EESSDHFLRVVQQDDSSDLQSPAKAPVLTTLDSFMEYMSTATAMPPGARED----DLSLP 104

Query: 315 LSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360
           +++Y+I+SSHNTYLTG+Q  SE+S + Y   L  GCRC+E+D WDG
Sbjct: 105 MTNYFINSSHNTYLTGNQLYSEASTDVYKDVLLKGCRCLEIDVWDG 150



 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 4/120 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I   +S L IY R  TFN    + +      + S  E   +     Q    F  ++   
Sbjct: 369  KILHALSRLGIYTRGYTFN-GFSQPEATKPTHIFSLSEATLKDAHENQRKALF-DHNKNF 426

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
            + R+YP G R++SSN +P   W  G+Q+ ALN+Q  DK M +N G F ++   G++LKP+
Sbjct: 427  MMRVYPSGMRVNSSNLDPSFSWRQGAQIAALNWQNCDKGMMLNKGMFARSK--GWVLKPE 484



 Score = 53.6 bits (123), Expect = 3e-05
 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 7/108 (6%)

Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424
           P + HG+TLT ++ F DV   I++ AF+TS+ P+I+S+E + S  QQ  M     + +  
Sbjct: 226 PRVLHGYTLTKEVTFRDVCYAIRDTAFVTSDLPVIVSLEVHASHEQQETMVEIMMEAWKG 285

Query: 425 LL------LVHPMDKNE-TSLPSPHDXXXXXXXXXXXXPEGAEESSFA 465
           +L      L   ++K++   LPSP              P+   E+  A
Sbjct: 286 MLVDFTPELAAELEKSDYKHLPSPDSLRNKILIKVKWAPDHGPETDVA 333


>UniRef50_Q0CXA3 Cluster: Putative uncharacterized protein; n=1;
           Aspergillus terreus NIH2624|Rep: Putative
           uncharacterized protein - Aspergillus terreus (strain
           NIH 2624)
          Length = 564

 Score = 74.5 bits (175), Expect = 2e-11
 Identities = 31/52 (59%), Positives = 40/52 (76%), Gaps = 1/52 (1%)

Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PD 362
           + P++ Y+ISSSHNTYLTG+Q SS+S   AY   L +GCRC+E+D WDG PD
Sbjct: 89  SHPMTDYFISSSHNTYLTGNQLSSDSDARAYAAVLLNGCRCVEIDVWDGEPD 140



 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 69/254 (27%), Positives = 109/254 (42%), Gaps = 36/254 (14%)

Query: 948  VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSN 1007
            +  NI   ++ G V+    S  E KA R    ++     +++     RIYP G R+ SSN
Sbjct: 303  IKVNITEAKVPGHVF----SLSE-KAARAAHAKDPEALFEHNRNHFMRIYPFGLRVTSSN 357

Query: 1008 YNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSI 1067
             +P  FW  G+Q+VALN+Q  DK + +N   F      G++LKP      GY   D    
Sbjct: 358  LDPSFFWRRGAQIVALNWQNVDKGVMLNRAMFADQR--GWVLKP-----PGYRSSDGAGS 410

Query: 1068 EGKVKPVTVMLRVIGARHL----CKTGRGTASPFVEVEI-IGADYDSGV----------- 1111
                K + + + VI  +++      T      P+V   + +  + D+ V           
Sbjct: 411  AIVRKQLDLSIEVIAGQNIPLPPGDTNEKGFHPYVACHLHVETEGDNAVGVPQGDDSTDS 470

Query: 1112 ---KLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQDEDIFGEPNFIGQATF 1164
                    T S  G NP   + + +F   +    EL  IRF V+D++ FG  +    A  
Sbjct: 471  EKSSYKRTTKSATGCNPDFGSQLIQFPTVSGIVDELTFIRFKVKDDE-FGRDSMAAWACI 529

Query: 1165 PLLCLRKGYRSVPL 1178
             L  L++GYR + L
Sbjct: 530  KLNHLQEGYRLIHL 543



 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 1/84 (1%)

Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420
           P   P + HGHTLT    F DV   I+++AF+T++ P+I+S+E +  L QQ+ M    ++
Sbjct: 213 PRPEPRVLHGHTLTKGTTFRDVCYAIRDNAFVTNDMPVIVSLEVHACLEQQQTMVEIMEE 272

Query: 421 VF-GDLLLVHPMDKNETSLPSPHD 443
            F G L+ V P  +    +P+P D
Sbjct: 273 AFKGMLIEVTPEIEATKIIPAPED 296


>UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3
           adaptor protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to SH2/SH3 adaptor protein -
           Strongylocentrotus purpuratus
          Length = 389

 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 31/83 (37%), Positives = 50/83 (60%)

Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           ++WFH   TR  +E++L      G FL+R SE   G FA+S +  + +KH +V +  + +
Sbjct: 289 RDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKKF 348

Query: 715 TIGTVKFESLIELVSYYENHPLY 737
            IG  KFESL +LV +Y+  P++
Sbjct: 349 CIGQRKFESLDDLVDHYKRSPIF 371



 Score = 56.4 bits (130), Expect = 4e-06
 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%)

Query: 745 PISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIIT 804
           P++     R    P  +T    PG   P S  ++V    +Y Y+A Q+DEL+  K   + 
Sbjct: 81  PVTRPISPRNSESPHPHTAQ--PGNEMPFSQPARV----MYHYKAAQEDELNLNKGEQVN 134

Query: 805 NVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
            ++K  +GWWRG+  G++  WFP+NYV E
Sbjct: 135 VLEKSGDGWWRGECNGEK-GWFPSNYVSE 162



 Score = 54.0 bits (124), Expect = 2e-05
 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 10/108 (9%)

Query: 531 NAIVPQDELHFAEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW 589
           N+  P   + F +  WFHG++   RQ++E +L        G FL+RES T  GD+ +S  
Sbjct: 276 NSFTPSSSVGFYDRDWFHGRIT--RQDSEKILGCPGE--SGLFLIRESETMPGDFAVSVK 331

Query: 590 RQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
              +V H ++    ++     + I    F+SL +L+ HY+  P+ S +
Sbjct: 332 APERVKHFKVTRSDKK-----FCIGQRKFESLDDLVDHYKRSPIFSSD 374



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           V V A +DY ++QD+ELS  ++  +  +D     WW+ +    R  + P+NYV
Sbjct: 7   VLVVAKWDYDSKQDEELSIKRNEKLKLID-DSRSWWKVEKQNGRCGYVPSNYV 58



 Score = 35.9 bits (79), Expect = 6.7
 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 8/100 (8%)

Query: 741 KLWYP---ISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSF 797
           K W+P   +SE+      S     +  G    + P  F   VT   LY ++ R D+EL+F
Sbjct: 152 KGWFPSNYVSEDDTSMPNSHGSSTSSKGDDNSI-PDDFVLGVTT--LYAFKGRTDEELNF 208

Query: 798 CKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIE 835
               ++  +  P  D+ WW+           P+NYV  +E
Sbjct: 209 DASELLDIISNPSDDQDWWKARNKLGTVGLVPSNYVKVVE 248


>UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 249

 Score = 73.7 bits (173), Expect = 3e-11
 Identities = 56/191 (29%), Positives = 96/191 (50%), Gaps = 20/191 (10%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV--KQEGRLY 714
           W+  + +R  A++ L      GAF++R S+   G F+IS R E +++H +V   ++GR Y
Sbjct: 58  WYKENTSRQSAQDELM-CQPIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQGRYY 116

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW----YPISEETVRRLVSEP----DDNTVYGT 766
            + +  F SL +LV YY ++ + K+ +++       S + + R  +E      +   Y +
Sbjct: 117 -LWSEMFTSLNKLVDYYTHNSISKQSRVFLLTDQRSSSDFLHRKPTEAPPFRQERQDYRS 175

Query: 767 --PGYMDPTS-----FTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819
             P    P+        S + V+A+YD+ A   DEL+F    +I  +D+ D  WW+G   
Sbjct: 176 LAPPVARPSQPSLPPQVSALHVRAMYDFTAEDADELNFQAGDVIEVLDQSDRSWWKGVLR 235

Query: 820 GKRHHWFPANY 830
           G R   FP NY
Sbjct: 236 G-RTGLFPVNY 245



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 9/91 (9%)

Query: 553 NRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYL 612
           +RQ A+D L        G F++R S +  GD+ +S   +  V H ++ ++  +G  ++YL
Sbjct: 64  SRQSAQDELMCQPI---GAFIIRGSQSSPGDFSISVRHENDVQHFKV-MRDRQG--RYYL 117

Query: 613 IDSMCFDSLYNLITHYRSHPL--RSQEFLIT 641
              M F SL  L+ +Y  + +  +S+ FL+T
Sbjct: 118 WSEM-FTSLNKLVDYYTHNSISKQSRVFLLT 147


>UniRef50_UPI0000DB7494 Cluster: PREDICTED: similar to CG10083-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to
           CG10083-PA - Apis mellifera
          Length = 472

 Score = 73.3 bits (172), Expect = 4e-11
 Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 7/165 (4%)

Query: 680 FLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKK 739
           ++ + S  E    AI    +K++ H +V++E ++    T   ++++  VS   + P   +
Sbjct: 310 YIPKNSHVEAAKKAIEESQQKDVSHIKVQEETKIIKNKTHNVDNIVTTVSNTSSSPNQVQ 369

Query: 740 VKLWYPISEETVRRLVSEP-DDNTVY----GTPGYMDPTSFTSKVTVKALYDYRARQDDE 794
                 I E     +  E   +N +Y    G   Y DP +   K   +ALYDY+A  D E
Sbjct: 370 ESKLSEIEESQQSSMTKEVVTENELYSQMDGQYLYFDPNNEGMKA--RALYDYQAADDTE 427

Query: 795 LSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHT 839
           ++F    IIT++D  DEGWW+G      +  FPANYV  I+   T
Sbjct: 428 ITFDPGDIITHIDAIDEGWWQGLGPDGTYGLFPANYVEVIDYSTT 472


>UniRef50_UPI0000E80974 Cluster: PREDICTED: hypothetical protein; n=1;
            Gallus gallus|Rep: PREDICTED: hypothetical protein -
            Gallus gallus
          Length = 184

 Score = 72.1 bits (169), Expect = 8e-11
 Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 1/100 (1%)

Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157
            V VEI G   D   +  TK + +NG NP W++  +F++  P+LAL+RFVV+D D     +
Sbjct: 77   VRVEIHGVPADQAHQ-ETKYIENNGFNPHWDETLQFQLHVPQLALVRFVVEDYDKTSRND 135

Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197
            F+GQ T     ++ GYR + L +     +  S+L VH+ I
Sbjct: 136  FVGQFTLAFANIKPGYRHIHLLSKDGTGIPPSSLFVHIRI 175


>UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras
           GTPase-activating protein 1 (GTPase-activating protein)
           (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP);
           n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to Ras GTPase-activating protein 1
           (GTPase-activating protein) (GAP) (Ras p21 protein
           activator) (p120GAP) (RasGAP) - Strongylocentrotus
           purpuratus
          Length = 628

 Score = 71.7 bits (168), Expect = 1e-10
 Identities = 36/122 (29%), Positives = 67/122 (54%), Gaps = 1/122 (0%)

Query: 642 LKEPVP-QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK 700
           L +PV  + + +EGK WFH + ++ +A E L K    G FL+R S+K  G +++SFR   
Sbjct: 221 LVKPVEGEIDPNEGKVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPN 280

Query: 701 EIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDD 760
            I+  R++++ R Y +G   + SL  +V +Y+   +    KL  P + +  +   +  +D
Sbjct: 281 TIQRFRIQKQQRQYVMGGRYYNSLDAIVDHYKKEEIIDGFKLRDPTAPKKFKNQTTSTED 340

Query: 761 NT 762
           ++
Sbjct: 341 SS 342



 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 1/91 (1%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715
           EW+H    R  AE  L   +  G++LVR SE++ GS+ +S+  ++ I H RV      + 
Sbjct: 67  EWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAVCGDFY 126

Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYP 745
           +G  +F++L EL+ YY +   + K  +L YP
Sbjct: 127 VGGRQFQTLPELIGYYTHISNILKNERLQYP 157



 Score = 44.8 bits (101), Expect = 0.014
 Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 15/114 (13%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L  +RQ AE  LR +A    G++LVRES    G Y LS+  Q  +NH R+     
Sbjct: 68  WYHGCL--DRQSAE--LRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRV----- 118

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKE 656
             V   + +    F +L  LI +Y   S+ L+++     L+ P P P   + K+
Sbjct: 119 TAVCGDFYVGGRQFQTLPELIGYYTHISNILKNER----LQYPAPPPEPVDDKK 168



 Score = 42.7 bits (96), Expect = 0.058
 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 13/132 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG ++  ++EA + L     +G   FL+R S    GDY LSF     +   RI+ KQ+
Sbjct: 237 WFHGNVS--KEEAAETLWKDGDIGG--FLIRNSDKNPGDYSLSFRGPNTIQRFRIQ-KQQ 291

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTR 664
           R     Y++    ++SL  ++ HY+   +        L++P   P K + +       + 
Sbjct: 292 RQ----YVMGGRYYNSLDAIVDHYKKEEIIDG---FKLRDPT-APKKFKNQTTSTEDSSP 343

Query: 665 TQAEELLRKTNT 676
              EEL R+ ++
Sbjct: 344 MNYEELRRRRSS 355


>UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor
           type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase
           non-receptor type 6 - Homo sapiens (Human)
          Length = 595

 Score = 71.7 bits (168), Expect = 1e-10
 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+G   +AE LL+       G+FL R S    GD+ LS     +V H RI   Q 
Sbjct: 4   WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56

Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660
            G   FY L     F +L  L+ +Y      L+ ++  +I LK P+   +    + W+H 
Sbjct: 57  SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113

Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711
           H +  QAE LL+       FLVR S  + G F +S  +++          + H +V  EG
Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173

Query: 712 RLYTIGTVK-FESLIELVSYYE 732
             YT+G ++ F+SL +LV +++
Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195



 Score = 39.9 bits (89), Expect = 0.41
 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597
           +E W+HG ++G   +AE LL+A       TFLVRES++  GD+ LS      + G  +  
Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162

Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629
           R   IK+  E G  ++ +     FDSL +L+ H++
Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195


>UniRef50_UPI000023E2BC Cluster: hypothetical protein FG08790.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG08790.1 - Gibberella zeae PH-1
          Length = 750

 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 31/54 (57%), Positives = 42/54 (77%), Gaps = 2/54 (3%)

Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSS--ESSLEAYVRCLRSGCRCIELDCWDG 360
           +D+++PL++Y+ISSSHNTYL G+Q +S   SS EAY   L  GCRCIE+D W+G
Sbjct: 162 KDLSKPLTNYFISSSHNTYLVGNQLASWNRSSPEAYKTVLLRGCRCIEIDVWNG 215



 Score = 65.7 bits (153), Expect = 7e-09
 Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 5/154 (3%)

Query: 933  RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992
            +I + +  L IY RS  +     + +  +   + S  E +   L  +Q    FV ++   
Sbjct: 464  KICENLGKLAIYTRSQHYKCLATK-EAKIPAHIFSISENRILELNQKQHREMFV-HNKGY 521

Query: 993  LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052
              R +P G+R DSSN +P  FW  G QMVA+N+Q  D+ M +N G F      G++LKP+
Sbjct: 522  FMRAFPAGRRFDSSNPDPSLFWRGGVQMVAMNWQYLDEGMMLNEGMFADEK--GWVLKPE 579

Query: 1053 FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL 1086
              ++      + +S     + + + + V+  +H+
Sbjct: 580  -GYQSSNTSTETQSDAAPGRTMNLRITVLAGQHI 612



 Score = 52.8 bits (121), Expect = 5e-05
 Identities = 24/72 (33%), Positives = 39/72 (54%)

Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420
           P   P + HG TLT    F +V R + E AF+ ++ P+I+S+E +    QQ  M    + 
Sbjct: 310 PKDEPIVTHGWTLTAPCGFREVCRAVGEAAFVDNDLPIIVSLEVHADEDQQEVMVKIMKQ 369

Query: 421 VFGDLLLVHPMD 432
            +G +L+  P+D
Sbjct: 370 EWGQMLVDKPLD 381


>UniRef50_A7EE08 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 686

 Score = 70.1 bits (164), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 5/121 (4%)

Query: 243 EFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD---IYEPYFTLSEFVEMLYSKQNSI 299
           E Q +LR    +  G +     +    +L D Q     + +  +   +F+E +Y   +  
Sbjct: 65  EIQEYLRKLFDELRGPEPCLGREKFEKWLADVQGHTITLEKDTYKFEQFLESVYYSHSLE 124

Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359
              +  ++  D +RP+++Y+ISSSHNTYL G+Q  S SS EAY   L   CRCIE+D  +
Sbjct: 125 VMKRIPEL--DQSRPITNYYISSSHNTYLEGNQLLSRSSTEAYKTALTQNCRCIEIDVHN 182

Query: 360 G 360
           G
Sbjct: 183 G 183



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 33/74 (44%), Positives = 43/74 (58%), Gaps = 4/74 (5%)

Query: 978  SQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037
            S +E  F   ++     R +P G+R DSSN +P   W  G QMVALN+QT D+ M +N G
Sbjct: 481  SNREQMF--AHNRNYFMRAFPAGKRFDSSNLDPSVCWRKGIQMVALNWQTLDEGMMLNEG 538

Query: 1038 KFKQNGGCGFILKP 1051
             F   G  G+ILKP
Sbjct: 539  MFA--GSQGWILKP 550



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 27/70 (38%), Positives = 39/70 (55%)

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
           G P + HG TLT  + F  V + I+E AF TS  P+I+S+E +    QQ  M    ++ +
Sbjct: 276 GEPLVLHGWTLTAPVGFRAVCKAIRETAFTTSPLPIIVSLEVHADHEQQEIMVDIMKEEW 335

Query: 423 GDLLLVHPMD 432
            DLLL  P +
Sbjct: 336 EDLLLDSPFE 345


>UniRef50_UPI0000D57984 Cluster: PREDICTED: similar to CG3637-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG3637-PA - Tribolium castaneum
          Length = 205

 Score = 68.9 bits (161), Expect = 8e-10
 Identities = 53/157 (33%), Positives = 79/157 (50%), Gaps = 15/157 (9%)

Query: 679 AFLVRPSEKEQGSFAISF-RTEKEIKHCRVKQEGR---LYTIGTVKFESLIELVSYYENH 734
           AFL + S+ E  S  +   ++  E K   + QE R       G +    L +  S  ENH
Sbjct: 56  AFLTQTSQAETPSGEVRVPKSLDESKKAFLAQETREEVRVVPGQLDQSKLAQFSS--ENH 113

Query: 735 PLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDE 794
            + ++ +  Y   E    ++ +E  +   Y T   +D     + ++  ALYDY+A  DDE
Sbjct: 114 EVNEEQEEIY---ENVTSQVTNEQQEEVYYTTDEIVD-----TGISAVALYDYQAAADDE 165

Query: 795 LSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +SF    IIT+++K DEGWWRG   GK +  FPANYV
Sbjct: 166 ISFDPDDIITHIEKIDEGWWRGLCKGK-YGLFPANYV 201


>UniRef50_Q966Z0 Cluster: Cortactin; n=1; Suberites domuncula|Rep:
           Cortactin - Suberites domuncula (Sponge)
          Length = 477

 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 31/61 (50%), Positives = 41/61 (67%), Gaps = 1/61 (1%)

Query: 771 DPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830
           +PT   S +  KA+YDY+A  +DE+SF    II N+++ DEGWW GD+ G R   FPANY
Sbjct: 415 EPTVVESGLRAKAVYDYQATGEDEISFDPDDIIENIEQVDEGWWIGDFNGNR-GLFPANY 473

Query: 831 V 831
           V
Sbjct: 474 V 474


>UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54;
           Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo
           sapiens (Human)
          Length = 380

 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 29/84 (34%), Positives = 50/84 (59%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713
           G+EW++ + TR QAE  L +   +G FL+R SE     F++S +   + KH +V+    +
Sbjct: 282 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 341

Query: 714 YTIGTVKFESLIELVSYYENHPLY 737
           Y IG  +F ++ ELV +Y+  P++
Sbjct: 342 YCIGQRRFHTMDELVEHYKKAPIF 365



 Score = 56.8 bits (131), Expect = 3e-06
 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833
           + Y A ++DELS  K + +T ++K  +GWWRG Y G +  WFP+NYVLE
Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 167



 Score = 42.7 bits (96), Expect = 0.058
 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +   R +AE  L      GD  FL+R+S +   D+ +S    GK  H +++L   
Sbjct: 285 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 337

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
             V   Y I    F ++  L+ HY+  P+ + E
Sbjct: 338 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 368



 Score = 39.5 bits (88), Expect = 0.54
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      R  + P+NYV
Sbjct: 2   TEEVIVIAKWDYTAQQDQELDIKKNERLWLLD-DSKTWWRVRNAANRTGYVPSNYV 56


>UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN
           full-length enriched library, clone:9930020J04
           product:similar to epidermal growth factor-receptor-
           binding protein GRB-4; n=5; Eutheria|Rep: Adult female
           vagina cDNA, RIKEN full-length enriched library,
           clone:9930020J04 product:similar to epidermal growth
           factor-receptor- binding protein GRB-4 - Mus musculus
           (Mouse)
          Length = 123

 Score = 68.1 bits (159), Expect = 1e-09
 Identities = 30/87 (34%), Positives = 50/87 (57%)

Query: 651 KHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710
           K  G  W++   TR QAE  L +   +G FL+R SE     F++S + + + KH +V+ +
Sbjct: 22  KFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLK 81

Query: 711 GRLYTIGTVKFESLIELVSYYENHPLY 737
             +Y IG  KF ++ ELV +Y+  P++
Sbjct: 82  ETVYCIGQRKFSTMEELVEHYKKAPIF 108



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 9/93 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++GK+   R +AE  L    H GD  FL+R+S +   D+ +S   QGK  H +++LK+ 
Sbjct: 28  WYYGKVT--RHQAEMALNERGHEGD--FLIRDSESSPNDFSVSLKAQGKNKHFKVQLKE- 82

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637
                 Y I    F ++  L+ HY+  P+ + E
Sbjct: 83  ----TVYCIGQRKFSTMEELVEHYKKAPIFTSE 111


>UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50;
           Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo
           sapiens (Human)
          Length = 1047

 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 2/94 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRLY 714
           +W+H    RT AEE LR+    G++L+R S++  GSF +SF ++   + H R+      Y
Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239

Query: 715 TIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
            IG  +F SL +L+ YY +   L K  KL YP++
Sbjct: 240 YIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 273



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK WFH   ++ +A  LL       +FLVRPS+   G +++ FRT + I+  ++
Sbjct: 342 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 401

Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765
                  + +G   + S+ +++ +Y    + +   L  P+  +   +++++  D   +Y 
Sbjct: 402 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 461

Query: 766 T 766
           T
Sbjct: 462 T 462



 Score = 46.8 bits (106), Expect = 0.004
 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%)

Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595
           +++ H  + WFHGK+  ++QEA +LL     +   +FLVR S    GDY L F     + 
Sbjct: 342 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 397

Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653
             +I           +++    ++S+ ++I HYR   +    +   LKEPVP  ++ +
Sbjct: 398 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 448



 Score = 43.2 bits (97), Expect = 0.044
 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR       G++L+RES    G + LSF  Q   VNH RI    
Sbjct: 181 WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 232

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P
Sbjct: 233 -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 277


>UniRef50_UPI0000F1F9FC Cluster: PREDICTED: similar to phospholipase
            C, beta 4,, partial; n=1; Danio rerio|Rep: PREDICTED:
            similar to phospholipase C, beta 4,, partial - Danio
            rerio
          Length = 348

 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 28/41 (68%), Positives = 33/41 (80%)

Query: 988  YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTP 1028
            Y+  Q+SRIYPKG R+DSSNY P  FWN G QMV+LN+QTP
Sbjct: 66   YNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTP 106



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 29/56 (51%), Positives = 39/56 (69%), Gaps = 2/56 (3%)

Query: 288 FVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342
           F   L S +N+ ++  + D + Q+M  PLSHY+ISSSHNTYLTG QF  +SS+E Y
Sbjct: 6   FCRYLMSDENAPVFLDRLD-LCQEMEHPLSHYFISSSHNTYLTGRQFGGKSSVEMY 60


>UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - Mus
           musculus (Mouse)
          Length = 166

 Score = 67.3 bits (157), Expect = 2e-09
 Identities = 50/146 (34%), Positives = 72/146 (49%), Gaps = 11/146 (7%)

Query: 690 GSFAISFRTEKEIKHCRVKQEGRLYTIGTVK-FESLIELVSYYENHPLYKKVKLWYPISE 748
           GS   + R   E+KH ++     LY I   K F  L+ELV +Y+ + L    K  +   +
Sbjct: 24  GSRQETRRYNVEVKHIKIMTSEGLYRITEKKAFRGLLELVEFYQQNSL----KDCFKSLD 79

Query: 749 ETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK 808
            T++    EP+   +   P     T +    T KA YD+ AR   ELS  +  II  ++K
Sbjct: 80  TTLQFPYKEPERRAISKPPA--GSTKYFG--TAKARYDFCARDRSELSLKEGDIIKILNK 135

Query: 809 P-DEGWWRGDYGGKRHHWFPANYVLE 833
              +GWWRG+  G R  WFP+NYV E
Sbjct: 136 KGQQGWWRGEIYG-RIGWFPSNYVEE 160


>UniRef50_A7SYD1 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 245

 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 29/53 (54%), Positives = 36/53 (67%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           VT  ALYDY+   D+E++F    IITN+++ DEGWWRG     RH  FPANYV
Sbjct: 189 VTATALYDYQQADDNEITFDPDDIITNIEQIDEGWWRGTGPDGRHGMFPANYV 241


>UniRef50_A2VCM4 Cluster: PLCH2 protein; n=6; Tetrapoda|Rep: PLCH2
           protein - Homo sapiens (Human)
          Length = 368

 Score = 66.9 bits (156), Expect = 3e-09
 Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 15/221 (6%)

Query: 102 CFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEF 157
           CF+IY+G+  +      V+ + +    WV G+ YL+A    E   A      ++WL++ F
Sbjct: 6   CFSIYHGSHRE--SLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTF 63

Query: 158 YSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKL 215
              + N    +++ EV   L K+N  +   +++ +F++ DT + +G +GF++F   Y+ +
Sbjct: 64  DEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM 123

Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275
               +  +D++     Y ++   +     Q FL+ EQ   +    +++ Q I +      
Sbjct: 124 ----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCP 177

Query: 276 RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT-RPL 315
            +  +    +  F     S    I++ ++  V QDMT RPL
Sbjct: 178 ENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQRPL 218


>UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;
           n=3; Mammalia|Rep: Growth factor receptor bound protein
           2 - Mus musculus (Mouse)
          Length = 203

 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 1/78 (1%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF     R +AEE+L K   DGAFL+R SE   G F++S +   +++H +V ++G   Y 
Sbjct: 60  WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119

Query: 716 IGTVKFESLIELVSYYEN 733
           +  VKF SL ELV Y+ +
Sbjct: 120 LWVVKFNSLNELVDYHRS 137



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 9/111 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+   R +AE++L    H  DG FL+RES +  GD+ LS      V H ++ L+  
Sbjct: 60  WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQPNKHEG 654
            G  K++L   + F+SL  L+ ++RS  + R+Q+  +   E +PQ +   G
Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQMPQEDGELG 162



 Score = 38.3 bits (85), Expect = 1.3
 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831
           A YD++A  DDELSF +  I+  +++  D+ W++ +  GK   + P NY+
Sbjct: 5   AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53


>UniRef50_Q0UVW3 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Phaeosphaeria nodorum (Septoria nodorum)
          Length = 819

 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 31/56 (55%), Positives = 38/56 (67%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +S  T  ALYDY A +D+E+SF ++A IT V+ PDE WW G Y GK    FPANYV
Sbjct: 761 SSGPTATALYDYEAAEDNEISFPENATITGVEFPDEDWWLGSYNGK-SGLFPANYV 815



 Score = 46.0 bits (104), Expect = 0.006
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           YDY   +D+E+   +   +T++D  DE WW G         FPANYV  +E
Sbjct: 677 YDYEKAEDNEVELREGEYVTDIDMVDEDWWMGTNSQGERGLFPANYVELVE 727


>UniRef50_A6SRW9 Cluster: Putative uncharacterized protein; n=1;
            Botryotinia fuckeliana B05.10|Rep: Putative
            uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 489

 Score = 66.5 bits (155), Expect = 4e-09
 Identities = 79/272 (29%), Positives = 121/272 (44%), Gaps = 39/272 (14%)

Query: 933  RIAKEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989
            +I + +S L IY  S   V+F++        ++    S  E     L  Q+    F +++
Sbjct: 210  KICESLSKLGIYTHSEHFVSFDVRAATKPSHIF----SVGEKVINELHEQKREQMF-QHN 264

Query: 990  TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049
                 R +P G R DSSN +P   W  G QMVALN+QT D+ M +N G F   G  G++L
Sbjct: 265  RNFFMRAFPAGSRFDSSNLDPSVCWRKGIQMVALNWQTLDEGMMLNEGMFA--GSQGWLL 322

Query: 1050 KPQFMFEEGYNPCDKKS-IEGKVKPVTVMLRV-IGARHLCKTGRGTAS----PFVEVEI- 1102
            KP      GY   D+KS I   +   T+ L++ I A        G       P+V+ E+ 
Sbjct: 323  KP-----PGYRSEDEKSDIWANIPYKTLDLKITIFAGQQIPYPEGETEKGFHPYVKCELH 377

Query: 1103 -----------IGADYDSGV-KLVTKTVSDNGLNP-LWNDICEFE-VAN--PELALIRFV 1146
                       IG D  +   +   KT   +G  P    +   FE + N   EL+ +RF 
Sbjct: 378  VESQEELNGQPIGNDVKAKEGEHKLKTAYKSGSKPDFEGETLHFEGIRNVVEELSFVRFK 437

Query: 1147 VQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178
            ++D + + +      A   L  L++GYR +PL
Sbjct: 438  IEDAN-YSKDELAAWACIRLDRLQQGYRLIPL 468



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 27/70 (38%), Positives = 40/70 (57%)

Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422
           G P + HG TLT  + F  V +TI+E+AF TS  P+I+S+E +    QQ  M    ++ +
Sbjct: 49  GEPLVLHGWTLTAPVGFRAVCKTIRENAFTTSPLPIIVSLEVHADHEQQEVMVDIMKEEW 108

Query: 423 GDLLLVHPMD 432
             LLL  P +
Sbjct: 109 EGLLLDSPFE 118


>UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3;
           Gallus gallus|Rep: Putative uncharacterized protein -
           Gallus gallus (Chicken)
          Length = 431

 Score = 66.1 bits (154), Expect = 5e-09
 Identities = 52/160 (32%), Positives = 77/160 (48%), Gaps = 12/160 (7%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  ++G   EAE LL        G+FL R S +  GD+ LS  R  +V H +I   Q 
Sbjct: 4   WFHPNISGI--EAEKLLLTRGV--HGSFLARPSKSNPGDFTLSVRRNDEVTHIKI---QN 56

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHP--LRSQEF-LITLKEPVPQPNKHEGKEWFHAH 661
            G   + L     F     L+ +Y      LR +   +I LK P+   +    + W+H H
Sbjct: 57  TG-DYYDLYGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLNCQDP-TSERWYHGH 114

Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701
            T  +AE+LL +    G+FLVR S+ + G F +S  T ++
Sbjct: 115 LTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSVLTNED 154



 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 7/98 (7%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           WFH + +  +AE+LL      G+FL RPS+   G F +S R   E+ H +++  G  Y +
Sbjct: 4   WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYDL 63

Query: 717 -GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747
            G  KF    ELV YY E   L ++     ++L YP++
Sbjct: 64  YGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLN 101



 Score = 37.1 bits (82), Expect = 2.9
 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 4/46 (8%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLS 587
           +E W+HG L G  +EAE LL        G+FLVRES +  GD+ LS
Sbjct: 107 SERWYHGHLTG--KEAEKLLTEKGK--PGSFLVRESQSKPGDFVLS 148


>UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF15108, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 877

 Score = 66.1 bits (154), Expect = 5e-09
 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 28/184 (15%)

Query: 664 RTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV-KQEGRLYTIGTVKF 721
           R QAE EL+ + N+   +LVR   +E   +AIS +   ++KH ++  +EG  Y     KF
Sbjct: 692 RLQAEAELINRVNS--TYLVRHRSREYTEYAISIKYNNDVKHIKILTKEGCFYIAENKKF 749

Query: 722 ESLIELVSYYENHPLYKKVK-----LWYPIS--EETVRRLVSEPDDNT------VYGTPG 768
            S+ EL+ YY++H L +  +     L +P    E    + ++ P  N        +  PG
Sbjct: 750 RSISELIEYYKHHSLREGFRSLDTTLHFPYRELENAAMQRLNRPGSNNPLLCGLSFVPPG 809

Query: 769 Y--MDPTS--FTSKVTVK------ALYDYRARQDDELSFCKHAIITNVDKPD-EGWWRGD 817
           Y  + P+S  F S +T K      A YD+ +R   ELS  +  ++    K    GWWRG+
Sbjct: 810 YSFVPPSSAPFWSVLTPKVIGVAIARYDFSSRDTRELSLQEGDVVKIYTKSGANGWWRGE 869

Query: 818 YGGK 821
             G+
Sbjct: 870 VHGR 873


>UniRef50_Q5AS57 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 784

 Score = 66.1 bits (154), Expect = 5e-09
 Identities = 33/61 (54%), Positives = 42/61 (68%), Gaps = 2/61 (3%)

Query: 772 PTSFTS-KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830
           PTS +  K T KALYDY A +D+ELSF + A I N++ PD+ WW G++ GK    FPANY
Sbjct: 721 PTSGSHVKPTAKALYDYEAAEDNELSFPEGAEIINIEFPDDDWWLGEFRGKT-GLFPANY 779

Query: 831 V 831
           V
Sbjct: 780 V 780



 Score = 41.1 bits (92), Expect = 0.18
 Identities = 16/51 (31%), Positives = 26/51 (50%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           YDY   +D+E+   +   +T ++  D+ WW G         FP+NYV  +E
Sbjct: 644 YDYEKAEDNEVDLREGEFVTEIEMVDKDWWLGSNAQGERGLFPSNYVELLE 694


>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
           Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
           aegypti (Yellowfever mosquito)
          Length = 939

 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 10/116 (8%)

Query: 544 CWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQ 603
           CWFHGK++  R+ AE++LR     G+G F+VRES +  GD+ LS   Q +V H +I+   
Sbjct: 8   CWFHGKIS--RERAEEILRQEG--GNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIR--- 60

Query: 604 ERGVTKFYLIDS-MCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKE 656
             G   F+ ID  M    L +LI HYR  S+ L ++   +    P P   +  GKE
Sbjct: 61  RHGDDAFFSIDDHMPIHGLDSLIEHYRESSNGLVTRLQTVCQSGPPPHDVRSHGKE 116



 Score = 54.8 bits (126), Expect = 1e-05
 Identities = 22/62 (35%), Positives = 37/62 (59%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709
           N+ E   WFH   +R +AEE+LR+   +G F+VR S   +G F +S   + E+ H ++++
Sbjct: 2   NREENLCWFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRR 61

Query: 710 EG 711
            G
Sbjct: 62  HG 63


>UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri
           tsingtauense|Rep: Bam32 - Branchiostoma belcheri
           tsingtauense
          Length = 250

 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 3/122 (2%)

Query: 653 EGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR 712
           E  +W+H   +R  AE LL     DG++L+R S    G +++S + +  +KH ++  +G+
Sbjct: 10  EQLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGK 69

Query: 713 LYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPD--DN-TVYGTPGY 769
            Y  G   F+SL E V ++ N PL                R V EPD  D  TV+ + G 
Sbjct: 70  QYQFGMGVFQSLQEFVEHFANQPLIGGESGILTALRHPYSRNVLEPDVYDTVTVHASLGQ 129

Query: 770 MD 771
            D
Sbjct: 130 QD 131



 Score = 49.6 bits (113), Expect = 5e-04
 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 11/103 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L+  R  AE LL A+A   DG++L+R S T VG+Y LS   +  V H +I     
Sbjct: 14  WYHGDLS--RHMAEALLMANAE--DGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWD-- 67

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEP 645
               K Y      F SL   + H+ + PL   E   L  L+ P
Sbjct: 68  ---GKQYQFGMGVFQSLQEFVEHFANQPLIGGESGILTALRHP 107


>UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase
           activating protein; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to ras gtpase activating protein -
           Nasonia vitripennis
          Length = 879

 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 1/91 (1%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715
           +W+H    R  AEE LR  +  G++LVR S+++ GS+ +S+     I H R+      Y 
Sbjct: 76  QWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 135

Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYP 745
           IG  +F SL++LV+YY +   L KK +L +P
Sbjct: 136 IGGRQFNSLMDLVAYYTHCSDLLKKERLIHP 166



 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 9/103 (8%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           WFH + T+++A ++L K    G+FLVRPS+   G +++ F    +I+  R++++G  Y +
Sbjct: 246 WFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 304

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPD 759
           G   FE L  +++ Y    + +            V+ +V+EPD
Sbjct: 305 GGRTFECLDAVINRYRKEQIVE--------GHTLVQAMVTEPD 339



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG+L  +R  AE+ LR  + LG  ++LVRES    G Y LS+  +  +NH RI     
Sbjct: 77  WYHGRL--DRFTAEERLRDASRLG--SYLVRESDRKPGSYVLSYLGRTGINHFRI----- 127

Query: 605 RGVTKFYLIDSMCFDSLYNLITHY-RSHPLRSQEFLITLKEPVPQP 649
             V   Y I    F+SL +L+ +Y     L  +E LI    P P+P
Sbjct: 128 TAVCGDYYIGGRQFNSLMDLVAYYTHCSDLLKKERLIH-PTPPPEP 172



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  +   + EA D+L      G G+FLVR S    GDY L F    ++   RI+ K  
Sbjct: 246 WFHPNVT--KSEAVDML---VKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 300

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHA 660
           R     YL+    F+ L  +I  YR   +     L+      P       KE  HA
Sbjct: 301 R-----YLMGGRTFECLDAVINRYRKEQIVEGHTLVQAMVTEPDGTVRVNKEVQHA 351


>UniRef50_Q4SVL5 Cluster: Chromosome undetermined SCAF13756, whole
           genome shotgun sequence; n=3; Tetraodontidae|Rep:
           Chromosome undetermined SCAF13756, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 450

 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 35/77 (45%), Positives = 45/77 (58%), Gaps = 5/77 (6%)

Query: 756 SEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWR 815
           ++ DD  +Y  P   + TS    V  +ALYDY+A  D E+SF    +IT ++  DEGWWR
Sbjct: 375 AQVDDTNLYEVPA--EETS-DKGVCARALYDYQAADDTEISFDPDEVITGIEMIDEGWWR 431

Query: 816 GDYGGKRHH-WFPANYV 831
           G YG   H   FPANYV
Sbjct: 432 G-YGPDGHFGMFPANYV 447


>UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and
           3-phosphotyrosine and 3- phosphoinositide; n=25;
           Euteleostomi|Rep: Dual adapter for phosphotyrosine and
           3-phosphotyrosine and 3- phosphoinositide - Homo sapiens
           (Human)
          Length = 280

 Score = 64.9 bits (151), Expect = 1e-08
 Identities = 32/102 (31%), Positives = 51/102 (50%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H + TR  AE LL     DG++L+R S +  G +++S R +  +KH  V+  G  +  
Sbjct: 35  WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758
           G  +F SL + V ++ N PL         + +    R V EP
Sbjct: 95  GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136



 Score = 42.3 bits (95), Expect = 0.077
 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R  AE LL ++    DG++L+R+S    G Y LS   +  V H  ++    
Sbjct: 35  WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648
               KF   +   F SL + + H+ + PL   E   L+ LK P P+
Sbjct: 91  S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131


>UniRef50_A2QHI3 Cluster: Contig An03c0200, complete genome; n=3;
           Trichocomaceae|Rep: Contig An03c0200, complete genome -
           Aspergillus niger
          Length = 782

 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 30/52 (57%), Positives = 37/52 (71%), Gaps = 1/52 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T  ALYDY A +D+ELSF + A ITN++ PD+ WW G+Y GK    FPANYV
Sbjct: 728 TATALYDYEAAEDNELSFPEGAEITNIEFPDDDWWFGEYLGKM-GLFPANYV 778



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 781 VKAL--YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +KAL  YDY   +D+E+   +   +TN++  D+ WW G         FP+NYV
Sbjct: 630 IKALVQYDYEKAEDNEIELKEGEYVTNIEMVDQDWWLGSNAQGDRGLFPSNYV 682


>UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep:
           Zgc:158474 protein - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 906

 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 35/93 (37%), Positives = 55/93 (59%), Gaps = 7/93 (7%)

Query: 542 AEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIK 600
           +EC WFHG L+  R +A  L+ A      G FLVR+S T  G+Y L+F  QGK  H R+ 
Sbjct: 711 SECQWFHGTLS--RLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLS 768

Query: 601 LKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
           L ++ G  +   +  + F S+++++ H+R HP+
Sbjct: 769 LNED-GQCR---VQHLWFQSIFDMLEHFRVHPI 797



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 23/84 (27%), Positives = 46/84 (54%), Gaps = 3/84 (3%)

Query: 656 EWFHAHCTRTQAEELLRKTN--TDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGR 712
           +WFH   +R +A +L+      + G FLVR SE  +G + ++F  + + KH R+   E  
Sbjct: 714 QWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEDG 773

Query: 713 LYTIGTVKFESLIELVSYYENHPL 736
              +  + F+S+ +++ ++  HP+
Sbjct: 774 QCRVQHLWFQSIFDMLEHFRVHPI 797


>UniRef50_Q9P7E8 Cluster: Protein app1; n=2; Fungi/Metazoa
           group|Rep: Protein app1 - Schizosaccharomyces pombe
           (Fission yeast)
          Length = 857

 Score = 64.1 bits (149), Expect = 2e-08
 Identities = 30/55 (54%), Positives = 39/55 (70%), Gaps = 1/55 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           +VKA+YDY+A++D+ELSF +  II NVD  D  WW G+  G R   FP+NYV EI
Sbjct: 804 SVKAIYDYQAQEDNELSFFEDEIIANVDCVDPNWWEGECHGHR-GLFPSNYVEEI 857



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 777 SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836
           +K     +YDY   +++E+   ++  I  ++  D+GWW G+    +   FP+NYV EI  
Sbjct: 726 TKTPAIVIYDYSPEEENEIELVENEQIQILEFVDDGWWLGENSKGQQGLFPSNYV-EITG 784

Query: 837 PHTPDVTSGLENESAALGSLQKGVLD 862
           P+        E ++   G   K + D
Sbjct: 785 PNETANNPPAEPQAGGPGKSVKAIYD 810


>UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6;
           Endopterygota|Rep: CG9209-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 954

 Score = 63.7 bits (148), Expect = 3e-08
 Identities = 28/90 (31%), Positives = 52/90 (57%), Gaps = 1/90 (1%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           WFH +CT+ +A ++L K    G+FLVRPS+   G +++ F    +I+  R++++G  Y +
Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 311

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPI 746
           G   FE L  +++ Y    + +   L +P+
Sbjct: 312 GGRTFECLDAVINRYRKEQIVEGHSLNHPV 341



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 1/93 (1%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715
           EW+H    R  AE  LR ++  G++LVR S+++ GS+ +S+     I H R+      + 
Sbjct: 83  EWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFY 142

Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
           IG  +F SL +LV YY +   L K+ +L  P++
Sbjct: 143 IGGRQFISLSDLVGYYTSCSDLLKRERLAIPVA 175



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 11/109 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG+L  +R  AE  LR  + LG  ++LVRES    G Y LS++ +  +NH RI     
Sbjct: 84  WYHGRL--DRYSAESRLRGSSKLG--SYLVRESDRKPGSYVLSYYGRTGINHFRI----- 134

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNK 651
             V   + I    F SL +L+ +Y   S  L+ +   I +  P P  +K
Sbjct: 135 TAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDK 183



 Score = 41.5 bits (93), Expect = 0.13
 Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 10/89 (11%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH     N  EA D+L      G G+FLVR S    GDY L F    ++   RI+ K  
Sbjct: 253 WFHPNCTKN--EAVDML---VKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 307

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
           R     YL+    F+ L  +I  YR   +
Sbjct: 308 R-----YLMGGRTFECLDAVINRYRKEQI 331


>UniRef50_Q7SXH4 Cluster: Cortactin, like; n=3; Danio rerio|Rep:
           Cortactin, like - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 206

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 30/53 (56%), Positives = 36/53 (67%), Gaps = 1/53 (1%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +T  ALYDY+A  DDE+SF    IITN++  DEGWWRG   G  +  FPANYV
Sbjct: 151 ITAVALYDYQAAGDDEISFDPDDIITNIEMIDEGWWRGVCRG-AYGLFPANYV 202


>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
           genome shotgun sequence; n=3; Tetraodontidae|Rep:
           Chromosome undetermined SCAF5507, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1116

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 36/98 (36%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 657 WFHAHCTRTQAEE-LLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ--EGRL 713
           WF     R QA+  LL   N++GAFL+R SEK+   + +S R+  ++KH +V Q  + R 
Sbjct: 69  WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128

Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETV 751
           Y     +F SL ELV YY+   L     L  P    T+
Sbjct: 129 YVEPGRRFSSLAELVDYYQKTSLNNAGPLGNPCKRNTL 166



 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 32/96 (33%), Positives = 55/96 (57%), Gaps = 3/96 (3%)

Query: 657 WFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE--GRL 713
           W++ +  R +AE+LL  + N DG+FLVR SE     + IS R+E ++ H R+++   G  
Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309

Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEE 749
           +    + F +L EL+SYY+ +     V L  P +++
Sbjct: 310 FVSDRISFATLGELISYYQRNNRSLGVLLEEPCAQQ 345



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 675 NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ--EGRLYTIGTVKFESLIELVSYYE 732
           N++GAFL+R SEK+   + +S R+  ++KH +V Q  + R Y     +F SL ELV YY+
Sbjct: 733 NSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLAELVDYYQ 792

Query: 733 NHPLYKKVKLWYPISEETV 751
              L     L  P    T+
Sbjct: 793 KTSLNNAGPLGNPCKRNTL 811



 Score = 52.0 bits (119), Expect = 1e-04
 Identities = 35/104 (33%), Positives = 59/104 (56%), Gaps = 9/104 (8%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W++G +  NR +AE LL A  +  DG+FLVR S +   +Y +S   +GKV H RI   Q 
Sbjct: 250 WYYGNI--NRVKAEKLLLASQNK-DGSFLVRISESHSDEYTISARSEGKVFHFRI---QR 303

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQ 648
             +  +++ D + F +L  LI++Y+ +   ++   + L+EP  Q
Sbjct: 304 SSIGAYFVSDRISFATLGELISYYQRN---NRSLGVLLEEPCAQ 344


>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
           Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 511

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 2/86 (2%)

Query: 653 EGKEWFHAHCTRTQA-EELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEG 711
           E + WF     R  A   L+   N  G+FLVR SE +   + +S RT++  KH ++ Q G
Sbjct: 130 ESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTG 189

Query: 712 -RLYTIGTVKFESLIELVSYYENHPL 736
            + Y     KF S++E++ +Y++HPL
Sbjct: 190 DQFYVDALFKFSSIVEVIEHYQSHPL 215



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 38/114 (33%), Positives = 54/114 (47%), Gaps = 12/114 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WF GK+  NR  A   L +  +   G+FLVR S +    Y LS   +    H +I    +
Sbjct: 134 WFFGKM--NRVGAVSHLMSDEN-NYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGD 190

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFL----ITLK-EPVPQPNKHE 653
           +    FY+     F S+  +I HY+SHPL   + L    I +K E VP P+  E
Sbjct: 191 Q----FYVDALFKFSSIVEVIEHYQSHPLSIGDLLSEPCIRIKPENVPPPSTDE 240


>UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1;
           Schistosoma japonicum|Rep: Clone ZZD1053 mRNA sequence -
           Schistosoma japonicum (Blood fluke)
          Length = 234

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 29/186 (15%)

Query: 657 WFHAHCTRTQAEELLRKTNT--------DGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK 708
           W+  HC+R +AEE L++ +         DGAF++R SE +   F++S +   E+ H +V 
Sbjct: 60  WYIRHCSRMEAEERLQEVDQETAQHLQPDGAFILRQSEADGKGFSLSVKQGCEVLHFKVL 119

Query: 709 Q-EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTP 767
           Q E   Y     +F+S+ +L+ +      ++K      IS   +  LV           P
Sbjct: 120 QDEAGKYFFWISRFDSVNQLIDH------HRKTS----ISRNRLLTLVDL--------VP 161

Query: 768 GYMDPTSFTSKV--TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHW 825
               PT+        V A +D+  +   ELS  +  +I  +++ DE WWRG     R   
Sbjct: 162 SKRFPTNVRKYQLDRVIARFDFITKDAGELSLHRGDVIEVINRDDENWWRGRTSDGRCGL 221

Query: 826 FPANYV 831
           FP+NYV
Sbjct: 222 FPSNYV 227


>UniRef50_Q2UPV5 Cluster: Predicted protein; n=2; Pezizomycotina|Rep:
            Predicted protein - Aspergillus oryzae
          Length = 218

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 59/203 (29%), Positives = 97/203 (47%), Gaps = 26/203 (12%)

Query: 995  RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ-F 1053
            RIYP G R++SSN +P  FW  G+Q+VALN+Q  DK M +N   F      G++LKPQ +
Sbjct: 2    RIYPYGLRVNSSNLDPSFFWRRGAQVVALNWQNLDKGMMLNSAMFADEQ--GWVLKPQGY 59

Query: 1054 MFEEGYNPCDKKSIEGKVKPVTVMLRVIGARH----------LC----KTGRGTASPFVE 1099
            +  +  +   ++ ++  ++ +      +   H          +C    +T   T SP  E
Sbjct: 60   LSSDAPSTIVRRQLDLSIEFLAGQNIPLPPGHTNEKHFHPYVVCDLHVETPEDTTSPHTE 119

Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQDEDIFGE 1155
             E  G       K + K+ S  G +P     + +F   +    EL+ +RF ++D++ FG 
Sbjct: 120  DE--GESETENHKQMIKSAS--GASPDFEGQMVQFPTLSGLVEELSFVRFKIKDDE-FGR 174

Query: 1156 PNFIGQATFPLLCLRKGYRSVPL 1178
             +    A   L  L++GYR V L
Sbjct: 175  DSTAAWACIRLDRLQEGYRLVHL 197


>UniRef50_Q14247 Cluster: Src substrate cortactin; n=44;
           Bilateria|Rep: Src substrate cortactin - Homo sapiens
           (Human)
          Length = 550

 Score = 63.3 bits (147), Expect = 4e-08
 Identities = 30/52 (57%), Positives = 36/52 (69%), Gaps = 1/52 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T  ALYDY+A  DDE+SF    IITN++  D+GWWRG   G R+  FPANYV
Sbjct: 496 TAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG-RYGLFPANYV 546


>UniRef50_UPI0000E1F7BD Cluster: PREDICTED: nitric oxide synthase
           trafficking isoform 4; n=2; Catarrhini|Rep: PREDICTED:
           nitric oxide synthase trafficking isoform 4 - Pan
           troglodytes
          Length = 563

 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 449 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 507

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 508 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 552


>UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 275

 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 28/175 (16%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716
           W+H    R + E +L      G +LVR S    G + +S     ++ H  +  +G +YTI
Sbjct: 9   WYHGVLKRVETEGILNG-KPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67

Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFT 776
           G   F  L  ++ +Y+ H L             T++  V   + N               
Sbjct: 68  GDQTFPDLPSIIEFYKKHFL----------DTTTLKEHVPNSECN--------------- 102

Query: 777 SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
             + VKALY +  + D++L F K  I+T + K ++ WW+      R    P  YV
Sbjct: 103 --IKVKALYAFPGKDDEDLPFKKGDILTVISKEEDNWWKARDSAGREGMIPKPYV 155



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 39/103 (37%), Positives = 48/103 (46%), Gaps = 14/103 (13%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           W+HG L   R E E +L        G +LVR+S T  GDY LS    GKV+H  I  K  
Sbjct: 9   WYHGVL--KRVETEGILNGKP---PGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNK-- 61

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVP 647
                 Y I    F  L ++I  Y+ H L +     TLKE VP
Sbjct: 62  ---GTMYTIGDQTFPDLPSIIEFYKKHFLDT----TTLKEHVP 97


>UniRef50_Q8IVI9 Cluster: Nostrin; n=22; Tetrapoda|Rep: Nostrin -
           Homo sapiens (Human)
          Length = 506

 Score = 62.9 bits (146), Expect = 5e-08
 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%)

Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788
           E    +  VK+  P   + +  +VS+         PG   P    ++++    KALY ++
Sbjct: 392 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 450

Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           ARQDDEL+  K  I+   +K +EGWW G   GK+ H FPA YV E+
Sbjct: 451 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 495


>UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal
           transduction protein lnk-realted; n=1; Nasonia
           vitripennis|Rep: PREDICTED: similar to signal
           transduction protein lnk-realted - Nasonia vitripennis
          Length = 458

 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 6/89 (6%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L   R +A  L+  +A  G GTFLVR+S T  G+Y L+F  QG+  H R+ L  +
Sbjct: 270 WFHGTLP--RSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRMTL-TD 326

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
           +G  +   +  + F ++Y+++ H+R +P+
Sbjct: 327 QGHCR---VQHLSFPAIYDMLDHFRQNPI 352



 Score = 44.8 bits (101), Expect = 0.014
 Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 3/83 (3%)

Query: 657 WFHAHCTRTQAEELLRKTNTDG--AFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714
           WFH    R+ A +L+    T+G   FLVR SE  +G + ++F  +   KH R+    + +
Sbjct: 270 WFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRMTLTDQGH 329

Query: 715 -TIGTVKFESLIELVSYYENHPL 736
             +  + F ++ +++ ++  +P+
Sbjct: 330 CRVQHLSFPAIYDMLDHFRQNPI 352


>UniRef50_Q6GMH1 Cluster: Zgc:91835; n=1; Danio rerio|Rep: Zgc:91835
           - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 496

 Score = 62.5 bits (145), Expect = 7e-08
 Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 2/69 (2%)

Query: 764 YGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRH 823
           + +P   +       +  +ALYDY+A  D E+SF    +I+ +D  DEGWWRG YG   H
Sbjct: 426 FQSPADEEENGDNQNICARALYDYQASDDTEISFDPDDVISGIDMIDEGWWRG-YGPDGH 484

Query: 824 H-WFPANYV 831
           +  FPANYV
Sbjct: 485 YGMFPANYV 493


>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
           Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 747

 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 37/84 (44%), Positives = 46/84 (54%), Gaps = 9/84 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG++   R+EAE+LL+      DG FLVRES  F GDY L      KV H RIK  + 
Sbjct: 378 WFHGRI--KREEAENLLKPRE---DGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAE- 431

Query: 605 RGVTKFYLIDSMCFDSLYNLITHY 628
               K  + D   FD+L  L+ HY
Sbjct: 432 ---NKLTIDDDEYFDNLGQLVEHY 452



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 2/76 (2%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRLYT 715
           WFH    R +AE LL K   DG FLVR S    G + +     ++++H R+K  E +L  
Sbjct: 378 WFHGRIKREEAENLL-KPREDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAENKLTI 436

Query: 716 IGTVKFESLIELVSYY 731
                F++L +LV +Y
Sbjct: 437 DDDEYFDNLGQLVEHY 452


>UniRef50_A1C8D2 Cluster: Actin binding protein, putative; n=4;
           Eurotiomycetidae|Rep: Actin binding protein, putative -
           Aspergillus clavatus
          Length = 791

 Score = 62.1 bits (144), Expect = 9e-08
 Identities = 27/49 (55%), Positives = 36/49 (73%), Gaps = 1/49 (2%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           ALYDY A +D+E+SF + A I N++ PD+ WW G+Y GK+   FPANYV
Sbjct: 740 ALYDYEAAEDNEVSFPEGAEILNIEFPDDDWWFGEYNGKK-GLFPANYV 787



 Score = 40.7 bits (91), Expect = 0.24
 Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 2/59 (3%)

Query: 780 TVKAL--YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836
           TV+A+  YDY   +D+E+   +   +++++  D+ WW G         FP+NYV  +E+
Sbjct: 638 TVRAIVQYDYEKAEDNEIDLKEGDYVSDIEMVDKDWWLGSNVHGHRGLFPSNYVELVEL 696


>UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Grb14 - Strongylocentrotus purpuratus
          Length = 756

 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 4/85 (4%)

Query: 652 HEGKEWFHAHCTRTQAEELLRKTN-TDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ- 709
           H  + WFH+  TR +   L  K    DG FL+R S++  G+F +SF   +++KH ++   
Sbjct: 655 HMTQPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINMV 714

Query: 710 EGRLYTI--GTVKFESLIELVSYYE 732
           E  +YTI  G  +F  LI+LV +Y+
Sbjct: 715 EDGVYTIDDGGTRFTDLIQLVEFYQ 739



 Score = 44.0 bits (99), Expect = 0.025
 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 9/93 (9%)

Query: 539 LHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598
           +H  + WFH  L  +   A   L A   + DG FL+RES    G + LSF    KV H +
Sbjct: 654 IHMTQPWFHSGLTRDETHA---LFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQ 710

Query: 599 IKLKQERGVTKFYLID--SMCFDSLYNLITHYR 629
           I + ++ GV   Y ID     F  L  L+  Y+
Sbjct: 711 INMVED-GV---YTIDDGGTRFTDLIQLVEFYQ 739


>UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome
           shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
           Chromosome 12 SCAF14993, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1136

 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 2/114 (1%)

Query: 636 QEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAIS 695
           +E    L  P    +      W+H    RT AEE LR+    G++L+R S++  GSF +S
Sbjct: 164 EEVAFPLSAPPSNHSPPRMPRWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLS 223

Query: 696 FRT-EKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747
           F +    + H R+      Y IG  +F SL +L+ YY     L K  KL  P++
Sbjct: 224 FLSMTNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPVA 277



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 22/60 (36%), Positives = 35/60 (58%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           + + HEGK W+H H T+ +A  LL       +FLVRPS+   G +++ FRT   I+  ++
Sbjct: 350 EEDPHEGKVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKI 409



 Score = 41.5 bits (93), Expect = 0.13
 Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 17/163 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603
           W+HGKL  +R  AE+ LR   +   G++L+RES    G + LSF      VNH RI    
Sbjct: 185 WYHGKL--DRTIAEERLRQARN--PGSYLIRESDRRPGSFVLSFLSMTNVVNHFRI---- 236

Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKEWFHAH 661
              +   Y I    F SL +LI +Y   S  L+ ++ L  +  P P  ++   +      
Sbjct: 237 -IAMCGDYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPVAPPEPVEDRRRVRAIL--P 293

Query: 662 CTRTQAEELLRKTNT--DGAFLVRPSEKEQGSFAIS-FRTEKE 701
            T+    + +R+ +T   G   +  +E + G   +S  RTE++
Sbjct: 294 YTKVPDTDEIRQVSTFLQGDMFIVHNELDDGWMWVSNVRTEEQ 336


>UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22;
           Amniota|Rep: GRB2-related adapter protein 2 - Homo
           sapiens (Human)
          Length = 330

 Score = 61.7 bits (143), Expect = 1e-07
 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%)

Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714
           +WFH   +R QAE LL      G F++R S+   G F+IS R E +++H +V ++ +  Y
Sbjct: 57  KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115

Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743
            + T KF SL +LV YY  + + ++ +++
Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +ALYD+ A +DDEL F    ++  +D  +  WW G    K    FPANYV
Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325



 Score = 41.9 bits (94), Expect = 0.10
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFH  L+  R +AE+LL        G F++R S +  GD+ +S   +  V H ++ ++  
Sbjct: 58  WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654
           +G    Y + +  F SL  L+ +YR++ + S++  I L++   +   H G
Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157


>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
           tyrosine kinase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to protein tyrosine kinase - Nasonia
           vitripennis
          Length = 739

 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 41/108 (37%), Positives = 56/108 (51%), Gaps = 7/108 (6%)

Query: 544 CWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQ 603
           CWFHG L+  R++AE LL       +GTFLVRES + +GDY LS    G+V H +I+   
Sbjct: 8   CWFHGNLS--REDAESLLLEDGR-DNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIR--- 61

Query: 604 ERGVTKFYLI-DSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           + G   F+ I D      L  LI +Y+    R    L T    +P P+
Sbjct: 62  KHGEDAFFSIDDETTIHGLETLIEYYQKENDRLVTILQTPIRGLPPPH 109



 Score = 46.4 bits (105), Expect = 0.005
 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 4/80 (5%)

Query: 657 WFHAHCTRTQAEELLRKTNTD-GAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR--L 713
           WFH + +R  AE LL +   D G FLVR S    G + +S   + E+ H ++++ G    
Sbjct: 9   WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68

Query: 714 YTI-GTVKFESLIELVSYYE 732
           ++I        L  L+ YY+
Sbjct: 69  FSIDDETTIHGLETLIEYYQ 88



 Score = 44.8 bits (101), Expect = 0.014
 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 2/102 (1%)

Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR 706
           +P K +  +W+H    R +A  LL K  + DG+FLVR SE+  G   ++    K   H +
Sbjct: 274 RPTKEKASDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQ 333

Query: 707 V-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPIS 747
           + K+   L+        SL  ++ +Y   P      L +PI+
Sbjct: 334 IQKRRNFLFIDNGPYLPSLEHVIEHYRCMPDGLPGPLIHPIA 375


>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
           kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
           similar to Abl tyrosine kinase CG4032-PA - Apis
           mellifera
          Length = 1439

 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 40/116 (34%), Positives = 58/116 (50%), Gaps = 6/116 (5%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709
           N  E   W+H    R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+ +
Sbjct: 167 NSLEKHSWYHGRICRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINE 225

Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI---SEETVRRLVSEPDD 760
             EG+++     KF +L ELV ++         +L YP    ++ TV  L  EPD+
Sbjct: 226 DSEGKMFVTTESKFNTLAELVHHHSMLADGLITQLLYPAPKHNKPTVFPLSPEPDE 281



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N + P + L     W+HG++   R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 161 NYVTPVNSLE-KHSWYHGRIC--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 214

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    E    K ++     F++L  L+ H   H + +   +  L  P P+ N
Sbjct: 215 EGRVYHYRI---NEDSEGKMFVTTESKFNTLAELVHH---HSMLADGLITQLLYPAPKHN 268

Query: 651 K 651
           K
Sbjct: 269 K 269


>UniRef50_Q9VDF4 Cluster: CG3637-PA; n=4; Diptera|Rep: CG3637-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 559

 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 27/49 (55%), Positives = 35/49 (71%), Gaps = 1/49 (2%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           ALYDY+A  DDE+SF    +IT+++K D+GWWRG     R+  FPANYV
Sbjct: 505 ALYDYQAADDDEISFDPDDVITHIEKIDDGWWRG-LCKNRYGLFPANYV 552


>UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33;
           Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens
           (Human)
          Length = 756

 Score = 60.9 bits (141), Expect = 2e-07
 Identities = 33/89 (37%), Positives = 51/89 (57%), Gaps = 6/89 (6%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG L+  R +A  L+        G FLVR+S T  G+Y L+F  QGK  H R+ L +E
Sbjct: 527 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
            G  +   +  + F S+++++ H+R HP+
Sbjct: 585 -GQCR---VQHLWFQSIFDMLEHFRVHPI 609



 Score = 52.4 bits (120), Expect = 7e-05
 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%)

Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709
           G  WFH   +R +A +L+    T + G FLVR SE  +G + ++F  + + KH R  + +
Sbjct: 524 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 583

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736
           EG+   +  + F+S+ +++ ++  HP+
Sbjct: 584 EGQC-RVQHLWFQSIFDMLEHFRVHPI 609


>UniRef50_UPI0000E47D05 Cluster: PREDICTED: similar to MGC84047
           protein; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to MGC84047 protein -
           Strongylocentrotus purpuratus
          Length = 299

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 26/53 (49%), Positives = 34/53 (64%)

Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           +T +ALYDY+A  D E++F    IIT +++ DEGWWRG         FPANYV
Sbjct: 244 MTARALYDYQAEDDTEVTFDPGDIITQIEQIDEGWWRGQAPSGEFGLFPANYV 296


>UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange
           factor 6 (Rac/Cdc42 guanine nucleotide exchange factor
           6) (PAK-interacting exchange factor alpha) (Alpha-Pix)
           (COOL-2).; n=1; Takifugu rubripes|Rep: Rho guanine
           nucleotide exchange factor 6 (Rac/Cdc42 guanine
           nucleotide exchange factor 6) (PAK-interacting exchange
           factor alpha) (Alpha-Pix) (COOL-2). - Takifugu rubripes
          Length = 664

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837
           ++TVKA ++++   +DELSF K  +I    + D GWW G   GK   WFP+NYV EI+  
Sbjct: 10  QLTVKARFNFKQNNEDELSFSKGDVIVVTRQEDGGWWEGTLNGKT-GWFPSNYVREIKPC 68

Query: 838 HTPDVTSGLE 847
             P    G +
Sbjct: 69  EKPVSPKGTQ 78


>UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome
           shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3
           SCAF14679, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 283

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 27/50 (54%), Positives = 33/50 (66%), Gaps = 1/50 (2%)

Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830
           VKALYD+ A +DDELSFC   +I  +D+ DE WW+G   G     FPANY
Sbjct: 234 VKALYDFTAEEDDELSFCAGDVIDVLDRSDESWWKGRLRG-NSGLFPANY 282



 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 2/88 (2%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715
           WF  + +R+ AEELLR     G F++R  +   G F+IS R E +++H +V ++ R  Y 
Sbjct: 58  WFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQYF 116

Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLW 743
           + + KF SL +LV +Y    + K  +++
Sbjct: 117 LWSEKFTSLNKLVDFYRTSSISKTREIY 144



 Score = 39.1 bits (87), Expect = 0.72
 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 10/98 (10%)

Query: 534 VPQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQG 592
           VPQ+ +      WF      +R  AE+LLR   H G G F++R   +  G++ +S   + 
Sbjct: 46  VPQNYIEIQTPRWFQEN--ASRSAAEELLR---HKGVGEFVIRGCQSSPGEFSISVRHES 100

Query: 593 KVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRS 630
            V H ++ ++  RG    Y + S  F SL  L+  YR+
Sbjct: 101 DVQHFKV-MRDSRGQ---YFLWSEKFTSLNKLVDFYRT 134



 Score = 36.7 bits (81), Expect = 3.8
 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837
           YD+ A  D ELSF K  I+  +  P++ W++ +  G +  + P NY+ EI+ P
Sbjct: 7   YDFMATGDTELSFRKGDIL-KILSPEDDWFKAEMNG-QEGYVPQNYI-EIQTP 56


>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
           - Drosophila melanogaster (Fruit fly)
          Length = 847

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 9/86 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG +   R EAE LL+      DG FLVRES  F GDY L    Q KV H R+K  + 
Sbjct: 479 WFHGSIT--RDEAEHLLQPRE---DGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLE- 532

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRS 630
               K  + D   F++L  L+ HY +
Sbjct: 533 ---NKLTIDDEEYFENLGQLVAHYEA 555



 Score = 53.2 bits (122), Expect = 4e-05
 Identities = 30/77 (38%), Positives = 43/77 (55%), Gaps = 2/77 (2%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715
           WFH   TR +AE LL+    DG FLVR S    G + +    + +++H RVK  E +L  
Sbjct: 479 WFHGSITRDEAEHLLQPRE-DGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTI 537

Query: 716 IGTVKFESLIELVSYYE 732
                FE+L +LV++YE
Sbjct: 538 DDEEYFENLGQLVAHYE 554


>UniRef50_Q9UJU6 Cluster: Drebrin-like protein; n=47;
           Euteleostomi|Rep: Drebrin-like protein - Homo sapiens
           (Human)
          Length = 430

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835
           +ALYDY+A  D E+SF    +IT ++  DEGWWRG YG   H   FPANYV  IE
Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430


>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
           Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
           melanogaster (Fruit fly)
          Length = 1620

 Score = 60.5 bits (140), Expect = 3e-07
 Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 12/120 (10%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+ +
Sbjct: 247 NSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISE 305

Query: 710 --EGRLYTIGTVKFESLIELVSY----YENHPLYKKVKLWYPISEE---TVRRLVSEPDD 760
             +G+++     KF +L ELV +    +E H L     L YP  ++   TV  L  EPD+
Sbjct: 306 DPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLI--TPLLYPAPKQNKPTVFPLSPEPDE 363



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 10/121 (8%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N + P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 241 NYVTPLNSLE-KHSWYHGPIS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 294

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    E    K ++     F++L  L+ H+ S P      +  L  P P+ N
Sbjct: 295 EGRVYHYRI---SEDPDGKVFVTQEAKFNTLAELV-HHHSVPHEGHGLITPLLYPAPKQN 350

Query: 651 K 651
           K
Sbjct: 351 K 351


>UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG17367-PB, isoform B - Tribolium castaneum
          Length = 488

 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 6/91 (6%)

Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602
           E WFHG L   R EA +L+      G G FLVR+S T  G++ L+F  QG+  H R+ + 
Sbjct: 320 EFWFHGTLG--RSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHLRMTI- 376

Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
            ++G  +   +    F S+Y ++ H+R  P+
Sbjct: 377 NDQGQCR---VQHFWFQSIYEMLEHFRQQPI 404



 Score = 44.4 bits (100), Expect = 0.019
 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%)

Query: 640 ITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNT--DGAFLVRPSEKEQGSFAISFR 697
           I+++  + Q  K E   WFH    R++A  L+        G FLVR SE   G F ++F 
Sbjct: 307 ISMETDIGQTLKKEF--WFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFN 364

Query: 698 TEKEIKHCR--VKQEGRLYTIGTVKFESLIELVSYYENHPL 736
            +   KH R  +  +G+   +    F+S+ E++ ++   P+
Sbjct: 365 FQGRAKHLRMTINDQGQC-RVQHFWFQSIYEMLEHFRQQPI 404


>UniRef50_Q804J4 Cluster: Phospholipase C gamma 1; n=6; Danio
           rerio|Rep: Phospholipase C gamma 1 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 50

 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 26/48 (54%), Positives = 37/48 (77%), Gaps = 1/48 (2%)

Query: 71  DIRDVKEVRTGKSSKDFERWPEE-TKRLESSKCFTIYYGTEFKLRCAS 117
           DIR++KE+RTG+ S+DFER+ E+ T R + + CF I YGTEF+L+  S
Sbjct: 1   DIREIKEIRTGQKSRDFERYVEDVTTRPDQAHCFVILYGTEFRLKSLS 48


>UniRef50_Q5M8F8 Cluster: Cortactin; n=2; Xenopus|Rep: Cortactin -
           Xenopus tropicalis (Western clawed frog) (Silurana
           tropicalis)
          Length = 553

 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 36/92 (39%), Positives = 45/92 (48%), Gaps = 8/92 (8%)

Query: 747 SEETVRRLVSEPDDNTVYGT-PGYMDPTSFTSK------VTVKALYDYRARQDDELSFCK 799
           +EE    +   PDD  +Y   P    P    S       +   ALYDY    DDE+SF  
Sbjct: 455 NEEDYEAVPDLPDDEALYEELPKEESPILIASSKQGGSGICAVALYDYEGGGDDEISFQP 514

Query: 800 HAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
             +IT++D  DEGWW G   G+R   FPANYV
Sbjct: 515 QELITDIDMLDEGWWCGTCEGRR-GLFPANYV 545


>UniRef50_O00851 Cluster: Unconventional myosin IB; n=2; Entamoeba
            histolytica|Rep: Unconventional myosin IB - Entamoeba
            histolytica
          Length = 1049

 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 30/54 (55%), Positives = 36/54 (66%), Gaps = 2/54 (3%)

Query: 781  VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
            VKALY Y A  D+ELSF    IIT ++K DEGWW+G+  G +  W P NYV EI
Sbjct: 998  VKALYPYTAANDEELSFKVGDIITILEK-DEGWWKGELNG-QEGWIPNNYVKEI 1049


>UniRef50_A4R8V8 Cluster: Putative uncharacterized protein; n=2;
           Sordariomycetes|Rep: Putative uncharacterized protein -
           Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 799

 Score = 60.1 bits (139), Expect = 4e-07
 Identities = 28/52 (53%), Positives = 35/52 (67%), Gaps = 1/52 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T  ALYDY A +D+ELSF + A + N++ PDE WW G + GK    FPANYV
Sbjct: 745 TATALYDYEAAEDNELSFPEGAKVMNLEFPDEDWWFGHFQGK-SGLFPANYV 795



 Score = 45.6 bits (103), Expect = 0.008
 Identities = 18/51 (35%), Positives = 27/51 (52%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           YDY A +D+E+       +T+++  DE WW G         FP+NYV  +E
Sbjct: 650 YDYEAAEDNEIELVDGQYVTDIEMVDEDWWMGTNSRGERGLFPSNYVELVE 700


>UniRef50_UPI0000D558FE Cluster: PREDICTED: similar to CG10083-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG10083-PA - Tribolium castaneum
          Length = 442

 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 27/56 (48%), Positives = 36/56 (64%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T  +  +ALYDY+A  D E+SF    IITN+D+ D+GWW+G      +  FPANYV
Sbjct: 383 TPGLQARALYDYQAVDDTEISFDPGDIITNIDQVDKGWWQGLAPNGTYGLFPANYV 438


>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
           Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
           (Human)
          Length = 488

 Score = 59.7 bits (138), Expect = 5e-07
 Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 649 PNKHEGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707
           P     + W+ +  +RTQA++LL    N  GAFL+RPSE   G +++S R + ++ H RV
Sbjct: 112 PETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRV 171

Query: 708 KQ--EGRLYTIGTVKFESLIELVSYYE 732
               +G LY      F  L EL++YY+
Sbjct: 172 SMAADGSLYLQKGRLFPGLEELLTYYK 198



 Score = 40.3 bits (90), Expect = 0.31
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%)

Query: 553 NRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYL 612
           +R +A+ LL +  +   G FL+R S + +G Y LS   Q KV H R+ +  +  +   YL
Sbjct: 126 SRTQAQQLLLSPPN-EPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL---YL 181

Query: 613 IDSMCFDSLYNLITHYRSH 631
                F  L  L+T+Y+++
Sbjct: 182 QKGRLFPGLEELLTYYKAN 200


>UniRef50_Q17M42 Cluster: Putative uncharacterized protein; n=1;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 393

 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 28/76 (36%), Positives = 43/76 (56%)

Query: 756 SEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWR 815
           +EP     +     +D +   + +  +ALYDY+A  + E+SF    IIT++D+ DEGWW+
Sbjct: 315 AEPVVQEFFDPNATIDLSDEDNMIKARALYDYQAADESEISFDPGDIITHIDQIDEGWWQ 374

Query: 816 GDYGGKRHHWFPANYV 831
           G      +  FPANYV
Sbjct: 375 GLAPDGTYGLFPANYV 390


>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
           n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
           - Spongilla lacustris (Freshwater sponge)
          Length = 505

 Score = 59.3 bits (137), Expect = 6e-07
 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 3/96 (3%)

Query: 653 EGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK--Q 709
           + +EWF     R +AE++L ++ N  G+FL+R SE   G F++S + +  ++H RV+  +
Sbjct: 118 DAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVRRLE 177

Query: 710 EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYP 745
           +G L+      F+ L ELV +Y+        KL YP
Sbjct: 178 DGSLFVTRRSTFQILHELVDHYKIETDGLCCKLLYP 213



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKL 601
           AE WF GK+   R EAE +L    +   G+FL+R+S T  GD+ LS   Q +V H R++ 
Sbjct: 119 AEEWFLGKI--KRVEAEKMLNQSFNQV-GSFLIRDSETTPGDFSLSVKDQDRVRHYRVR- 174

Query: 602 KQERGVTKFYLIDSMCFDSLYNLITHYR 629
           + E G    ++     F  L+ L+ HY+
Sbjct: 175 RLEDG--SLFVTRRSTFQILHELVDHYK 200



 Score = 37.9 bits (84), Expect = 1.7
 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWW--RGDYGGKRHHWFPANYVLE 833
           YDY +R DD+LSF K  ++  +   +  WW  R      +  + P+NYV E
Sbjct: 63  YDYDSRTDDDLSFKKGDLMYIISTDEGDWWFARSKDTAGKEGYIPSNYVAE 113


>UniRef50_UPI00015B5756 Cluster: PREDICTED: similar to GA10060-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA10060-PA - Nasonia vitripennis
          Length = 542

 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 30/71 (42%), Positives = 42/71 (59%), Gaps = 2/71 (2%)

Query: 769 YMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828
           Y+DP +   K   +ALYDY+A  D E++F    IIT++D  DEGWW+G      +  FPA
Sbjct: 474 YLDPNNQGMKA--RALYDYQAADDTEITFDPGDIITHIDAIDEGWWQGLAPDGTYGLFPA 531

Query: 829 NYVLEIEVPHT 839
           N+V  I+   T
Sbjct: 532 NHVEVIDYGST 542


>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
           proto-oncogene tyrosine-protein kinase abl1; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to
           proto-oncogene tyrosine-protein kinase abl1 - Nasonia
           vitripennis
          Length = 1522

 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 6/116 (5%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+ +
Sbjct: 168 NSLEKHSWYHGRISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINE 226

Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI---SEETVRRLVSEPDD 760
             +G++Y      F +L ELV ++         +L YP    ++ TV  L  EPD+
Sbjct: 227 DSDGKMYVTTESIFNTLAELVHHHSMLADGLITQLLYPAPKRNKPTVFPLSPEPDE 282



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 38/121 (31%), Positives = 59/121 (48%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N + P + L     W+HG+++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 162 NYVTPVNSLE-KHSWYHGRIS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 215

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    E    K Y+     F++L  L+ H   H + +   +  L  P P+ N
Sbjct: 216 EGRVYHYRI---NEDSDGKMYVTTESIFNTLAELVHH---HSMLADGLITQLLYPAPKRN 269

Query: 651 K 651
           K
Sbjct: 270 K 270


>UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus
           tropicalis|Rep: Nck1-prov protein. - Xenopus tropicalis
          Length = 345

 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVL-EIEVPHTPDVT 843
           + Y A +DDELS  K   +  ++K  +GWWRG Y G R  WFP+NYV  E + P    V 
Sbjct: 115 FTYTAERDDELSLVKGTKVIVMEKCSDGWWRGSYNG-RVGWFPSNYVTEENDSPSGDQVG 173

Query: 844 SGLENESAALGSLQKG 859
           +  E  +A + +L  G
Sbjct: 174 TLTEKLAAVVNNLNNG 189



 Score = 37.5 bits (83), Expect = 2.2
 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +V V A +DY A+QD EL   K+  +  +D   + WWR      +  + P+NYV
Sbjct: 3   TEEVIVVAKFDYVAQQDQELDIKKNERLWLLD-DSKSWWRVRNSMNKTGFVPSNYV 57



 Score = 36.3 bits (80), Expect = 5.1
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISF 696
           G +W++   TR QAE  L +   +G FL+R SE    +   S+
Sbjct: 279 GNQWYYGKVTRHQAEMALNERGNEGDFLIRDSESSVSNLGHSY 321


>UniRef50_O96459 Cluster: SRC8; n=2; Strongylocentrotus
           purpuratus|Rep: SRC8 - Strongylocentrotus purpuratus
           (Purple sea urchin)
          Length = 587

 Score = 58.8 bits (136), Expect = 8e-07
 Identities = 28/50 (56%), Positives = 36/50 (72%), Gaps = 1/50 (2%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           KALYDY+A  +DEL+F  + IIT+V+  D+GWW+G   GK    FPANYV
Sbjct: 533 KALYDYQATAEDELTFDPNEIITHVETIDDGWWKGVCRGK-VGLFPANYV 581


>UniRef50_Q4S1M8 Cluster: Chromosome 6 SCAF14768, whole genome
           shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 6
           SCAF14768, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 634

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 25/51 (49%), Positives = 35/51 (68%), Gaps = 1/51 (1%)

Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835
           +DY A+QDDELS     II N+ + D GWW G+ GG+R  +FP N+V E++
Sbjct: 7   FDYEAQQDDELSLTVGDIIVNIRRDDGGWWEGELGGRR-GFFPDNFVREMK 56



 Score = 45.2 bits (102), Expect = 0.011
 Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 5/58 (8%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYV--LEIE 835
           K L+ Y A+ +DELS  +  II  + K   D GWW G+ GG R   FP N+V  LE+E
Sbjct: 274 KVLFPYEAQNEDELSIKEGDIINIITKDCADAGWWMGETGG-RQGVFPDNFVKLLELE 330



 Score = 39.5 bits (88), Expect = 0.54
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)

Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
           KA + Y  + +DEL      +I  + + +EGWW G   GK    FP+N+  EI
Sbjct: 110 KAAFSYLPQHEDELELKAGDVIEILAEVEEGWWEGLLNGKT-GMFPSNFTKEI 161


>UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted;
           n=2; Endopterygota|Rep: Signal transduction protein
           lnk-realted - Aedes aegypti (Yellowfever mosquito)
          Length = 564

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 6/89 (6%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG LA  R EA  L+  +     G FLVR+S T  G++ L+F  QGK  H R+ L  +
Sbjct: 419 WFHGTLA--RSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTL-ND 475

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
            G  +   +  + F S+  ++ H+R HP+
Sbjct: 476 LGQCR---VQHLWFPSITEMLEHFRQHPI 501



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 657 WFHAHCTRTQAEELLRKT--NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRL 713
           WFH    R++A +L+     ++ G FLVR SE  +G F ++F  + + KH R+   +   
Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTLNDLGQ 478

Query: 714 YTIGTVKFESLIELVSYYENHPL 736
             +  + F S+ E++ ++  HP+
Sbjct: 479 CRVQHLWFPSITEMLEHFRQHPI 501


>UniRef50_Q12897 Cluster: Phospholipase C-like; n=16;
           Euteleostomi|Rep: Phospholipase C-like - Homo sapiens
           (Human)
          Length = 59

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 25/54 (46%), Positives = 37/54 (68%), Gaps = 1/54 (1%)

Query: 701 EIKHCRVKQEGRLYTIGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRR 753
           ++KHCR+ ++      G    FESL+ELVSYYE H LY+K++L YP++ E + R
Sbjct: 4   KVKHCRINRDAGTLCWGPPPIFESLVELVSYYEKHSLYRKMRLCYPVTPELLER 57


>UniRef50_Q5KHY4 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 693

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 2/98 (2%)

Query: 767 PGYMDPTSFTSKV--TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH 824
           P  ++P S  S      K LYDY A +D+ELS  +  IIT +++ DEGWW G     +  
Sbjct: 510 PRTIEPASEPSPAGKRAKVLYDYDAAEDNELSLREDDIITQIEQLDEGWWSGTNADGQSG 569

Query: 825 WFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLD 862
            FPANY   IE    P      + E  A    +  ++D
Sbjct: 570 LFPANYCELIEDDSAPAANPQYQVEPEAELETEPTIID 607



 Score = 50.0 bits (114), Expect = 4e-04
 Identities = 24/60 (40%), Positives = 36/60 (60%), Gaps = 1/60 (1%)

Query: 773 TSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVL 832
           +S+     + A YDY A +D+ELSF +   IT+++K D  WW+G   G +   FPA YV+
Sbjct: 626 SSYAKDTVMIAAYDYDASEDNELSFKEGDQITDIEKIDPDWWQGKCNG-QEGLFPAAYVV 684


>UniRef50_P19706 Cluster: Myosin heavy chain IB; n=5; Eukaryota|Rep:
            Myosin heavy chain IB - Acanthamoeba castellanii (Amoeba)
          Length = 1147

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 29/58 (50%), Positives = 35/58 (60%), Gaps = 1/58 (1%)

Query: 777  SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834
            +K  VKALYDY A+  DEL+F +   I    K   GWW G+  GKR  W PANYV +I
Sbjct: 1091 AKPQVKALYDYDAQTGDELTFKEGDTIIVHQKDPAGWWEGELNGKR-GWVPANYVQDI 1147


>UniRef50_Q6C2N2 Cluster: Class E vacuolar protein-sorting machinery
           protein HSE1; n=1; Yarrowia lipolytica|Rep: Class E
           vacuolar protein-sorting machinery protein HSE1 -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 685

 Score = 58.4 bits (135), Expect = 1e-06
 Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 761 NTVYGTPGYMDPTSFTSKVT-VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819
           NT    P   DPT   + V+ VKALYD  A +  ELSF K  IIT ++     WWRG   
Sbjct: 234 NTNNNAPAVEDPTPTVATVSRVKALYDLNATEPGELSFRKGDIITVLESVFRDWWRGSLR 293

Query: 820 GKRHHWFPANYVLEIEVPHTPDVTSGLENE 849
           G +   FP NYV+ I  P   ++    + E
Sbjct: 294 G-QVGIFPLNYVMPIAEPTPAEIEKEAQEE 322


>UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).;
           n=1; Gallus gallus|Rep: SH2B adapter protein 3
           (Lymphocyte-specific adapter protein Lnk) (Signal
           transduction protein Lnk) (Lymphocyte adapter protein).
           - Gallus gallus
          Length = 506

 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 7/100 (7%)

Query: 535 PQDELHFAEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593
           P+ E   + C WFHG ++  R +A  L++     G G FLVR+S T  G+Y L+F  QG+
Sbjct: 377 PKMEQFLSSCPWFHGPIS--RVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGR 434

Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633
             H R+ L  ERG  +   +  + F S+  ++ H+  +P+
Sbjct: 435 AKHLRLSL-TERGQCR---VQHLRFSSITEMLHHFHRYPI 470



 Score = 48.4 bits (110), Expect = 0.001
 Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 3/83 (3%)

Query: 657 WFHAHCTRTQAEELLRKTNTDG--AFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRL 713
           WFH   +R +A +L++    +G   FLVR SE  +G + ++F  +   KH R+   E   
Sbjct: 388 WFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLSLTERGQ 447

Query: 714 YTIGTVKFESLIELVSYYENHPL 736
             +  ++F S+ E++ ++  +P+
Sbjct: 448 CRVQHLRFSSITEMLHHFHRYPI 470


>UniRef50_A0JMM6 Cluster: Zgc:154014; n=11; Eumetazoa|Rep:
           Zgc:154014 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 550

 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 25/52 (48%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           T +A+YDY+    DE+SF    IITN++  DEGWW+G   G R   FPA++V
Sbjct: 497 TARAIYDYQGEDSDEISFMPDDIITNIEMVDEGWWKGMCNG-RTGLFPASFV 547


>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
           fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
           fluviatilis
          Length = 485

 Score = 58.0 bits (134), Expect = 1e-06
 Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 11/108 (10%)

Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604
           WFHG+++  R++AE LL    +   G FLVRES  + GDY L     G+V + R++ + E
Sbjct: 109 WFHGRIS--REDAEKLLTPPKN---GRFLVRESQNYPGDYTLCVSYDGRVENYRVR-RNE 162

Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKH 652
           +G+    + D   FD+L  L+ HY+     +      LK PV +  +H
Sbjct: 163 KGLVT--VDDDEYFDNLIKLVEHYQK---EADGLCTRLKAPVDKEGQH 205



 Score = 48.8 bits (111), Expect = 9e-04
 Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 3/106 (2%)

Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715
           WFH   +R  AE+LL     +G FLVR S+   G + +    +  +++ RV++ E  L T
Sbjct: 109 WFHGRISREDAEKLLTPPK-NGRFLVRESQNYPGDYTLCVSYDGRVENYRVRRNEKGLVT 167

Query: 716 IGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDD 760
           +   + F++LI+LV +Y+        +L  P+ +E     V + +D
Sbjct: 168 VDDDEYFDNLIKLVEHYQKEADGLCTRLKAPVDKEGQHLFVVDVND 213


>UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to
           1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma 1 (Phosphoinositide
           phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1)
           (PLC-II) (PLC-148); n=1; Gallus gallus|Rep: PREDICTED:
           similar to 1-phosphatidylinositol-4,5-bisphosphate
           phosphodiesterase gamma 1 (Phosphoinositide
           phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1)
           (PLC-II) (PLC-148) - Gallus gallus
          Length = 131

 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 34/73 (46%), Positives = 42/73 (57%), Gaps = 6/73 (8%)

Query: 538 ELHFAECWFHGKLAGNR---QEAEDLLRAHA-HLGD--GTFLVRESVTFVGDYCLSFWRQ 591
           ELH A+ WFHGKL   R     A+ LL  +   +G   G+FLVRES  FVGD+ LS W  
Sbjct: 50  ELHLAQDWFHGKLGAGRGGWHIAKWLLTEYCTEMGPPCGSFLVRESEIFVGDFVLSIWCD 109

Query: 592 GKVNHCRIKLKQE 604
            KV H  I  +Q+
Sbjct: 110 EKVQHFHIHWQQD 122


>UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo
           sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo
           sapiens (Human)
          Length = 498

 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%)

Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708
           N  E   W+H   +R  AE LL  +  +G+FLVR SE   G  +IS R E  + H R+  
Sbjct: 372 NSLEKHSWYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 430

Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731
             +G+LY     +F +L ELV ++
Sbjct: 431 ASDGKLYVSSESRFNTLAELVHHH 454



 Score = 50.8 bits (116), Expect = 2e-04
 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%)

Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590
           N I P + L     W+HG ++  R  AE LL +  +   G+FLVRES +  G   +S   
Sbjct: 366 NYITPVNSLE-KHSWYHGPVS--RNAAEHLLSSGIN---GSFLVRESESSPGQRSISLRY 419

Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650
           +G+V H RI    +    K Y+     F++L  L+ H   H   +   + TL  P P+ N
Sbjct: 420 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 473

Query: 651 K 651
           K
Sbjct: 474 K 474


>UniRef50_Q6CEP4 Cluster: Yarrowia lipolytica chromosome B of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome B of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 837

 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 26/49 (53%), Positives = 34/49 (69%), Gaps = 1/49 (2%)

Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831
           ALYDY A +D+ELSF    IIT+++  DE WW G   GKR + FP+N+V
Sbjct: 786 ALYDYDAAEDNELSFAADDIITDIEFIDEDWWTGSLNGKR-NLFPSNFV 833



 Score = 44.8 bits (101), Expect = 0.014
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 2/68 (2%)

Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV--LE 833
           +SK +    YDY   ++ E+   +  I+T+++  DE WW G         FP+NYV   +
Sbjct: 696 SSKPSATVEYDYTKDEEGEIDLVEDEIVTDIEFLDENWWSGTNSKGESGLFPSNYVRLKD 755

Query: 834 IEVPHTPD 841
             VP  PD
Sbjct: 756 GAVPTIPD 763


>UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor 6;
           n=14; Tetrapoda|Rep: Rho guanine nucleotide exchange
           factor 6 - Homo sapiens (Human)
          Length = 776

 Score = 57.6 bits (133), Expect = 2e-06
 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%)

Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834
           ++ VKA ++++   +DELS CK  II      + GWW G   G R  WFP+NYV EI   
Sbjct: 162 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 220

Query: 835 EVPHTPDVTSGLE 847
           E P +P    G E
Sbjct: 221 ERPLSPKAVKGFE 233


>UniRef50_Q6GM14 Cluster: MGC84047 protein; n=9; Tetrapoda|Rep:
           MGC84047 protein - Xenopus laevis (African clawed frog)
          Length = 376

 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 28/76 (36%), Positives = 40/76 (52%)

Query: 760 DNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819
           ++T    P Y    +  S +  +ALYDY+A  D E+SF    +I  ++  D+GWWRG   
Sbjct: 301 EDTPQEDPVYETGVAEDSGMCARALYDYQAADDTEISFDPDDVIIQIEMIDDGWWRGVAP 360

Query: 820 GKRHHWFPANYVLEIE 835
                 FPANYV  +E
Sbjct: 361 SGHFGMFPANYVELLE 376


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.136    0.416 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,337,361,673
Number of Sequences: 1657284
Number of extensions: 57110858
Number of successful extensions: 125952
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 559
Number of HSP's successfully gapped in prelim test: 566
Number of HSP's that attempted gapping in prelim test: 123409
Number of HSP's gapped (non-prelim): 2262
length of query: 1201
length of database: 575,637,011
effective HSP length: 109
effective length of query: 1092
effective length of database: 394,993,055
effective search space: 431332416060
effective search space used: 431332416060
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 78 (35.5 bits)

- SilkBase 1999-2023 -