BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000600-TA|BGIBMGA000600-PA|IPR008973|C2 calcium/lipid-binding region, CaLB, IPR002048|Calcium-binding EF-hand, IPR000008|C2 calcium-dependent membrane targeting, IPR000980|SH2 motif, IPR001452|Src homology-3, IPR000909|Phosphatidylinositol-specific phospholipase C, X region, IPR001711|Phosphatidylinositol-specific phospholipase C, Y domain, IPR001849|Pleckstrin-like, IPR001192|Phosphoinositide-specific phospholipase C, C-terminal (PLC), IPR013841|Phosphatidylinositol-specific phospholipase C, X and Y boxes (1201 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA;... 1552 0.0 UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gamb... 1438 0.0 UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|R... 1272 0.0 UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-... 1150 0.0 UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 1141 0.0 UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|... 1078 0.0 UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Ph... 812 0.0 UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whol... 803 0.0 UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3;... 700 0.0 UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome s... 654 0.0 UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome sho... 357 1e-96 UniRef50_UPI0000E493A1 Cluster: PREDICTED: similar to phospholip... 266 2e-69 UniRef50_A7RPT6 Cluster: Predicted protein; n=2; Nematostella ve... 258 5e-67 UniRef50_Q3LUA8 Cluster: Phospholipase C-eta2; n=23; Euteleostom... 248 7e-64 UniRef50_O75038 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 248 7e-64 UniRef50_Q4KWH8 Cluster: Phospholipase C eta 1; n=45; Tetrapoda|... 244 1e-62 UniRef50_UPI000069FB22 Cluster: 1-phosphatidylinositol-4,5-bisph... 242 5e-62 UniRef50_UPI0000F1F4FE Cluster: PREDICTED: similar to phospholip... 238 6e-61 UniRef50_Q9BRC7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 237 2e-60 UniRef50_Q8K3R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 236 2e-60 UniRef50_UPI0000F1EF3B Cluster: PREDICTED: hypothetical protein;... 234 9e-60 UniRef50_A5D6R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 232 4e-59 UniRef50_Q8N3E9 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 231 9e-59 UniRef50_P51178 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 231 1e-58 UniRef50_Q4RX70 Cluster: Chromosome 11 SCAF14979, whole genome s... 225 6e-57 UniRef50_Q4SNU6 Cluster: Chromosome 15 SCAF14542, whole genome s... 223 2e-56 UniRef50_UPI000069F421 Cluster: phospholipase C delta 3; n=1; Xe... 220 2e-55 UniRef50_Q5QIB9 Cluster: Phospholipase C delta isoform; n=6; Str... 219 3e-55 UniRef50_UPI00006609DC Cluster: Homolog of Brachydanio rerio "Ph... 217 1e-54 UniRef50_Q86XJ2 Cluster: PLCH2 protein; n=8; Euteleostomi|Rep: P... 216 3e-54 UniRef50_UPI000065E113 Cluster: Homolog of Homo sapiens "PhosPho... 215 8e-54 UniRef50_O97037 Cluster: PLC-deltaH; n=1; Hydra magnipapillata|R... 212 4e-53 UniRef50_P40977 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 212 6e-53 UniRef50_Q9UPR0 Cluster: Inactive phospholipase C-like protein 2... 211 1e-52 UniRef50_A7SDH9 Cluster: Predicted protein; n=1; Nematostella ve... 210 2e-52 UniRef50_Q4RY83 Cluster: Chromosome 3 SCAF14978, whole genome sh... 207 2e-51 UniRef50_UPI000069E9FD Cluster: phospholipase C, delta 4; n=1; X... 205 7e-51 UniRef50_Q86YW0 Cluster: Phospholipase C zeta 1; n=7; Eutheria|R... 196 2e-48 UniRef50_Q08AQ7 Cluster: PLCZ1 protein; n=19; Amniota|Rep: PLCZ1... 196 2e-48 UniRef50_UPI0000EB12AF Cluster: phospholipase C-like 3; n=1; Can... 195 5e-48 UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholip... 194 1e-47 UniRef50_Q4RKI8 Cluster: Chromosome 21 SCAF15029, whole genome s... 193 2e-47 UniRef50_A0BLC4 Cluster: Chromosome undetermined scaffold_114, w... 192 4e-47 UniRef50_Q5CR08 Cluster: Phospholipase C, delta 1 ortholog with ... 192 5e-47 UniRef50_Q4RSB2 Cluster: Chromosome 13 SCAF15000, whole genome s... 192 6e-47 UniRef50_UPI000023F2A0 Cluster: hypothetical protein FG05898.1; ... 189 5e-46 UniRef50_A7RKT2 Cluster: Predicted protein; n=1; Nematostella ve... 188 6e-46 UniRef50_UPI0000E49F73 Cluster: PREDICTED: similar to KIAA1092 p... 188 1e-45 UniRef50_UPI00006CFB88 Cluster: Phosphatidylinositol-specific ph... 188 1e-45 UniRef50_Q4T850 Cluster: Chromosome 16 SCAF7896, whole genome sh... 185 6e-45 UniRef50_UPI000069FB24 Cluster: 1-phosphatidylinositol-4,5-bisph... 184 1e-44 UniRef50_UPI0000E817B6 Cluster: PREDICTED: hypothetical protein;... 183 2e-44 UniRef50_A7SXK4 Cluster: Predicted protein; n=1; Nematostella ve... 182 5e-44 UniRef50_A2QRK1 Cluster: Catalytic activity: 1-phosphatidyl-1D-m... 182 7e-44 UniRef50_Q02158 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 182 7e-44 UniRef50_UPI0000DB73F3 Cluster: PREDICTED: similar to no recepto... 180 2e-43 UniRef50_P78585 Cluster: Phosphoinositide-specific phospholipase... 180 2e-43 UniRef50_Q15147 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 180 3e-43 UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate pho... 179 4e-43 UniRef50_Q27J08 Cluster: Phospholipase C; n=1; Aplysia californi... 178 6e-43 UniRef50_Q21754 Cluster: Phospholipase c protein 4; n=2; Caenorh... 178 9e-43 UniRef50_UPI00006CB024 Cluster: Phosphatidylinositol-specific ph... 176 3e-42 UniRef50_A2TJ25 Cluster: Phospholipase C beta 3; n=8; Clupeoceph... 175 5e-42 UniRef50_Q5MG88 Cluster: Phospholipase C delta 1; n=2; Toxoplasm... 174 1e-41 UniRef50_Q9TZN8 Cluster: Phosphoinositide-specific phospholipase... 174 1e-41 UniRef50_Q8IA75 Cluster: Phospholipase c like protein 1, isoform... 173 3e-41 UniRef50_O97036 Cluster: PLC-betaH2; n=2; Eukaryota|Rep: PLC-bet... 172 4e-41 UniRef50_Q9NBA8 Cluster: Phospholipase C; n=3; Decapodiformes|Re... 171 1e-40 UniRef50_Q4S530 Cluster: Chromosome 6 SCAF14737, whole genome sh... 171 1e-40 UniRef50_O97035 Cluster: PLC-betaH1; n=1; Hydra magnipapillata|R... 170 2e-40 UniRef50_UPI000065E6FA Cluster: 1-phosphatidylinositol-4,5-bisph... 169 3e-40 UniRef50_A3LSB2 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 169 5e-40 UniRef50_P13217 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 169 5e-40 UniRef50_P25455 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 168 7e-40 UniRef50_A4IGD0 Cluster: Plcb3 protein; n=11; Euteleostomi|Rep: ... 168 9e-40 UniRef50_Q4S9T4 Cluster: Chromosome 2 SCAF14695, whole genome sh... 167 2e-39 UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome sh... 167 2e-39 UniRef50_Q16ZC0 Cluster: Phospholipase c epsilon; n=1; Aedes aeg... 167 2e-39 UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 167 2e-39 UniRef50_A7S279 Cluster: Predicted protein; n=1; Nematostella ve... 165 5e-39 UniRef50_Q4FXB0 Cluster: Phosphatidylinositol-specific phospholi... 165 9e-39 UniRef50_Q9NQ66 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 165 9e-39 UniRef50_Q9TVI2 Cluster: Putative uncharacterized protein plc-1;... 164 1e-38 UniRef50_Q4Q6Z7 Cluster: Phospholipase c-like protein; n=2; Leis... 163 3e-38 UniRef50_Q95X29 Cluster: Egg laying defective protein 8, isoform... 160 2e-37 UniRef50_A0C336 Cluster: Chromosome undetermined scaffold_146, w... 160 2e-37 UniRef50_A0CKY8 Cluster: Chromosome undetermined scaffold_20, wh... 156 3e-36 UniRef50_Q4TBY5 Cluster: Chromosome undetermined SCAF7071, whole... 156 4e-36 UniRef50_Q01970 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 156 4e-36 UniRef50_Q6CD33 Cluster: Similar to DEHA0A04554g Debaryomyces ha... 155 5e-36 UniRef50_Q5KJZ5 Cluster: Phosphoinositide phospholipase C, putat... 153 2e-35 UniRef50_Q4PA81 Cluster: Putative uncharacterized protein; n=1; ... 153 3e-35 UniRef50_O97033 Cluster: PLC-betaS; n=1; Ephydatia fluviatilis|R... 151 1e-34 UniRef50_Q75C92 Cluster: ACR024Wp; n=1; Eremothecium gossypii|Re... 151 1e-34 UniRef50_Q00722 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 151 1e-34 UniRef50_Q6FY00 Cluster: Similar to sp|P32383 Saccharomyces cere... 150 3e-34 UniRef50_A3KGF7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 149 3e-34 UniRef50_UPI00015A791C Cluster: UPI00015A791C related cluster; n... 149 5e-34 UniRef50_P32383 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 148 8e-34 UniRef50_A7TR21 Cluster: Putative uncharacterized protein; n=1; ... 147 1e-33 UniRef50_O13433 Cluster: 1-phosphatidylinositol-4,5-bisphosphate... 140 2e-31 UniRef50_UPI00015551EC Cluster: PREDICTED: hypothetical protein,... 135 8e-30 UniRef50_Q0UC00 Cluster: Putative uncharacterized protein; n=1; ... 134 1e-29 UniRef50_A5DAA1 Cluster: Putative uncharacterized protein; n=1; ... 134 2e-29 UniRef50_Q6CSI9 Cluster: Similar to sp|P32383 Saccharomyces cere... 129 4e-28 UniRef50_Q766D4 Cluster: Phosphoinositide-specific phospholipase... 125 8e-27 UniRef50_A7PP48 Cluster: Chromosome chr8 scaffold_23, whole geno... 124 1e-26 UniRef50_P93620 Cluster: Phosphoinositide-specific phospholipase... 124 1e-26 UniRef50_UPI0000F1F9F9 Cluster: PREDICTED: similar to 1-phosphat... 123 3e-26 UniRef50_Q762E2 Cluster: Phosphoinositide-specific phospholipase... 123 3e-26 UniRef50_Q56W08 Cluster: Phosphoinositide-specific phospholipase... 123 3e-26 UniRef50_Q8GV43 Cluster: Phosphoinositide-specific phospholipase... 122 8e-26 UniRef50_UPI0000E493BE Cluster: PREDICTED: similar to ENSANGP000... 120 2e-25 UniRef50_A7T500 Cluster: Predicted protein; n=4; cellular organi... 118 7e-25 UniRef50_Q4YWB8 Cluster: Phospholipase C-like, putative; n=4; Pl... 118 1e-24 UniRef50_Q944C1 Cluster: Phosphoinositide-specific phospholipase... 117 2e-24 UniRef50_Q9LUZ0 Cluster: Phosphoinositide-specific phospholipase... 116 3e-24 UniRef50_A5K7G0 Cluster: Phospholipase C-like, putative; n=3; Pl... 116 3e-24 UniRef50_Q8IJR0 Cluster: Phospholipase C-like, putative; n=1; Pl... 116 4e-24 UniRef50_A5AGR6 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-24 UniRef50_Q9AXF1 Cluster: Phosphoinositide-specific phospholipase... 114 1e-23 UniRef50_A6RM87 Cluster: Putative uncharacterized protein; n=1; ... 113 2e-23 UniRef50_Q9XWB7 Cluster: Putative uncharacterized protein plc-2;... 110 2e-22 UniRef50_Q236T7 Cluster: Phosphatidylinositol-specific phospholi... 109 3e-22 UniRef50_UPI00015A74B5 Cluster: UPI00015A74B5 related cluster; n... 108 1e-21 UniRef50_A4S165 Cluster: Predicted protein; n=1; Ostreococcus lu... 107 2e-21 UniRef50_UPI0001555F0C Cluster: PREDICTED: hypothetical protein,... 103 3e-20 UniRef50_Q4QBH9 Cluster: Phosphoinositide-specific phospholipase... 102 7e-20 UniRef50_Q4SCY7 Cluster: Chromosome 14 SCAF14646, whole genome s... 101 9e-20 UniRef50_A5E691 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-19 UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphat... 100 3e-19 UniRef50_Q013R6 Cluster: Phosphoinositide-specific phospholipase... 100 3e-19 UniRef50_A7ASE0 Cluster: Phospholipase C gamma 1, putative; n=1;... 100 3e-19 UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-ty... 99 8e-19 UniRef50_Q0UE70 Cluster: Putative uncharacterized protein; n=4; ... 97 2e-18 UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: ... 94 2e-17 UniRef50_A4RIZ5 Cluster: Putative uncharacterized protein; n=2; ... 92 1e-16 UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; ... 91 1e-16 UniRef50_Q4N7P5 Cluster: Phospholipase C, putative; n=2; Theiler... 91 2e-16 UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-recept... 89 7e-16 UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew;... 89 9e-16 UniRef50_Q2H4G2 Cluster: Putative uncharacterized protein; n=1; ... 86 5e-15 UniRef50_Q9STZ3 Cluster: 1-phosphatidylinositol-4, 5-bisphosphat... 85 8e-15 UniRef50_Q7SE08 Cluster: Putative uncharacterized protein NCU021... 85 1e-14 UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2;... 83 3e-14 UniRef50_Q2H674 Cluster: Putative uncharacterized protein; n=1; ... 83 6e-14 UniRef50_UPI0000F1F414 Cluster: PREDICTED: hypothetical protein;... 82 1e-13 UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth fac... 82 1e-13 UniRef50_A4RFY5 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-13 UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bil... 81 2e-13 UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep:... 80 4e-13 UniRef50_Q86YU7 Cluster: FLJ00417 protein; n=4; Tetrapoda|Rep: F... 80 4e-13 UniRef50_Q5IRA3 Cluster: Phosphatidyl inositol-specific phosphol... 80 4e-13 UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: ... 80 4e-13 UniRef50_Q0UVV5 Cluster: Putative uncharacterized protein; n=1; ... 79 5e-13 UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 ad... 79 7e-13 UniRef50_UPI000023D8AD Cluster: hypothetical protein FG06693.1; ... 79 1e-12 UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygot... 78 1e-12 UniRef50_A6RBI2 Cluster: Predicted protein; n=1; Ajellomyces cap... 77 3e-12 UniRef50_A2QEJ2 Cluster: Catalytic activity: 1-phosphatidyl-1D-m... 77 3e-12 UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome sh... 75 1e-11 UniRef50_Q5B933 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-11 UniRef50_Q4WX21 Cluster: Phosphoinositide-specific phospholipase... 75 2e-11 UniRef50_Q1E522 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-11 UniRef50_Q0CXA3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-11 UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 ad... 74 3e-11 UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65... 74 3e-11 UniRef50_UPI0000DB7494 Cluster: PREDICTED: similar to CG10083-PA... 73 4e-11 UniRef50_UPI0000E80974 Cluster: PREDICTED: hypothetical protein;... 72 8e-11 UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase... 72 1e-10 UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-recept... 72 1e-10 UniRef50_UPI000023E2BC Cluster: hypothetical protein FG08790.1; ... 70 3e-10 UniRef50_A7EE08 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-10 UniRef50_UPI0000D57984 Cluster: PREDICTED: similar to CG3637-PA;... 69 8e-10 UniRef50_Q966Z0 Cluster: Cortactin; n=1; Suberites domuncula|Rep... 69 1e-09 UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleo... 69 1e-09 UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-le... 68 1e-09 UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; ... 68 2e-09 UniRef50_UPI0000F1F9FC Cluster: PREDICTED: similar to phospholip... 67 2e-09 UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - M... 67 2e-09 UniRef50_A7SYD1 Cluster: Predicted protein; n=2; Nematostella ve... 67 3e-09 UniRef50_A2VCM4 Cluster: PLCH2 protein; n=6; Tetrapoda|Rep: PLCH... 67 3e-09 UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2;... 66 4e-09 UniRef50_Q0UVW3 Cluster: Putative uncharacterized protein; n=3; ... 66 4e-09 UniRef50_A6SRW9 Cluster: Putative uncharacterized protein; n=1; ... 66 4e-09 UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; ... 66 5e-09 UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whol... 66 5e-09 UniRef50_Q5AS57 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-09 UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 65 1e-08 UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsin... 65 1e-08 UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase... 65 1e-08 UniRef50_Q4SVL5 Cluster: Chromosome undetermined SCAF13756, whol... 65 1e-08 UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-... 65 1e-08 UniRef50_A2QHI3 Cluster: Contig An03c0200, complete genome; n=3;... 64 2e-08 UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|R... 64 2e-08 UniRef50_Q9P7E8 Cluster: Protein app1; n=2; Fungi/Metazoa group|... 64 2e-08 UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygot... 64 3e-08 UniRef50_Q7SXH4 Cluster: Cortactin, like; n=3; Danio rerio|Rep: ... 63 4e-08 UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 63 4e-08 UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 63 4e-08 UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schis... 63 4e-08 UniRef50_Q2UPV5 Cluster: Predicted protein; n=2; Pezizomycotina|... 63 4e-08 UniRef50_Q14247 Cluster: Src substrate cortactin; n=44; Bilateri... 63 4e-08 UniRef50_UPI0000E1F7BD Cluster: PREDICTED: nitric oxide synthase... 63 5e-08 UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella ve... 63 5e-08 UniRef50_Q8IVI9 Cluster: Nostrin; n=22; Tetrapoda|Rep: Nostrin -... 63 5e-08 UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal tra... 62 7e-08 UniRef50_Q6GMH1 Cluster: Zgc:91835; n=1; Danio rerio|Rep: Zgc:91... 62 7e-08 UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 62 9e-08 UniRef50_A1C8D2 Cluster: Actin binding protein, putative; n=4; E... 62 9e-08 UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2... 62 1e-07 UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome s... 62 1e-07 UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; A... 62 1e-07 UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 61 2e-07 UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 61 2e-07 UniRef50_Q9VDF4 Cluster: CG3637-PA; n=4; Diptera|Rep: CG3637-PA ... 61 2e-07 UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|... 61 2e-07 UniRef50_UPI0000E47D05 Cluster: PREDICTED: similar to MGC84047 p... 60 3e-07 UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange ... 60 3e-07 UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome sh... 60 3e-07 UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 60 3e-07 UniRef50_Q9UJU6 Cluster: Drebrin-like protein; n=47; Euteleostom... 60 3e-07 UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 60 3e-07 UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB... 60 4e-07 UniRef50_Q804J4 Cluster: Phospholipase C gamma 1; n=6; Danio rer... 60 4e-07 UniRef50_Q5M8F8 Cluster: Cortactin; n=2; Xenopus|Rep: Cortactin ... 60 4e-07 UniRef50_O00851 Cluster: Unconventional myosin IB; n=2; Entamoeb... 60 4e-07 UniRef50_A4R8V8 Cluster: Putative uncharacterized protein; n=2; ... 60 4e-07 UniRef50_UPI0000D558FE Cluster: PREDICTED: similar to CG10083-PA... 60 5e-07 UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 60 5e-07 UniRef50_Q17M42 Cluster: Putative uncharacterized protein; n=1; ... 59 6e-07 UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 59 6e-07 UniRef50_UPI00015B5756 Cluster: PREDICTED: similar to GA10060-PA... 59 8e-07 UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 59 8e-07 UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus... 59 8e-07 UniRef50_O96459 Cluster: SRC8; n=2; Strongylocentrotus purpuratu... 59 8e-07 UniRef50_Q4S1M8 Cluster: Chromosome 6 SCAF14768, whole genome sh... 58 1e-06 UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted... 58 1e-06 UniRef50_Q12897 Cluster: Phospholipase C-like; n=16; Euteleostom... 58 1e-06 UniRef50_Q5KHY4 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-06 UniRef50_P19706 Cluster: Myosin heavy chain IB; n=5; Eukaryota|R... 58 1e-06 UniRef50_Q6C2N2 Cluster: Class E vacuolar protein-sorting machin... 58 1e-06 UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocy... 58 1e-06 UniRef50_A0JMM6 Cluster: Zgc:154014; n=11; Eumetazoa|Rep: Zgc:15... 58 1e-06 UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 58 1e-06 UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphat... 58 2e-06 UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; H... 58 2e-06 UniRef50_Q6CEP4 Cluster: Yarrowia lipolytica chromosome B of str... 58 2e-06 UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor ... 58 2e-06 UniRef50_Q6GM14 Cluster: MGC84047 protein; n=9; Tetrapoda|Rep: M... 57 3e-06 UniRef50_Q6DEM2 Cluster: V-crk sarcoma virus CT10 oncogene homol... 57 3e-06 UniRef50_Q567F1 Cluster: Zgc:112091; n=2; Euteleostomi|Rep: Zgc:... 57 3e-06 UniRef50_Q4SBL7 Cluster: Chromosome 15 SCAF14667, whole genome s... 57 3e-06 UniRef50_Q4S596 Cluster: Chromosome 19 SCAF14731, whole genome s... 57 3e-06 UniRef50_P14317 Cluster: Hematopoietic lineage cell-specific pro... 57 3e-06 UniRef50_A2RQD6 Cluster: Bcr-abl1 e6a2 chimeric protein; n=10; E... 57 3e-06 UniRef50_A2RQD3 Cluster: Bcr-abl1 e13a3 chimeric protein; n=21; ... 57 3e-06 UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 57 3e-06 UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 57 3e-06 UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 57 3e-06 UniRef50_UPI0000EB037D Cluster: Hematopoietic lineage cell-speci... 56 4e-06 UniRef50_Q5ZMV0 Cluster: Putative uncharacterized protein; n=2; ... 56 4e-06 UniRef50_Q9XUT0 Cluster: Putative uncharacterized protein; n=2; ... 56 4e-06 UniRef50_Q16NH5 Cluster: Cortactin; n=1; Aedes aegypti|Rep: Cort... 56 4e-06 UniRef50_A6RRT4 Cluster: Putative uncharacterized protein; n=3; ... 56 4e-06 UniRef50_UPI00005A2ADA Cluster: PREDICTED: similar to drebrin-li... 56 6e-06 UniRef50_Q4TEV6 Cluster: Chromosome undetermined SCAF5071, whole... 56 6e-06 UniRef50_Q16H73 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-06 UniRef50_Q5VSN0 Cluster: SH3-domain kinase binding protein 1; n=... 56 6e-06 UniRef50_Q96B97 Cluster: SH3 domain-containing kinase-binding pr... 56 6e-06 UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 56 6e-06 UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 56 6e-06 UniRef50_UPI0000D56E93 Cluster: PREDICTED: similar to SH2 domain... 56 8e-06 UniRef50_Q9Y0S9 Cluster: CG9749-PA; n=7; Endopterygota|Rep: CG97... 56 8e-06 UniRef50_A5E386 Cluster: Reduced viability upon starvation prote... 56 8e-06 UniRef50_Q4RUM3 Cluster: Chromosome 12 SCAF14993, whole genome s... 55 1e-05 UniRef50_Q9DAC8 Cluster: Adult male testis cDNA, RIKEN full-leng... 55 1e-05 UniRef50_Q95PW9 Cluster: Temporarily assigned gene name protein ... 55 1e-05 UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 55 1e-05 UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 55 1e-05 UniRef50_UPI0000F318C3 Cluster: SH2B adapter protein 3 (Lymphocy... 55 1e-05 UniRef50_Q5RJ36 Cluster: Novel protein similar to vertebrate lym... 55 1e-05 UniRef50_P50745 Cluster: SH2B adapter protein 3; n=3; Rattus nor... 55 1e-05 UniRef50_Q9UQQ2 Cluster: SH2B adapter protein 3; n=15; Tetrapoda... 55 1e-05 UniRef50_O14492 Cluster: SH2B adapter protein 2; n=7; Tetrapoda|... 55 1e-05 UniRef50_Q9VU84 Cluster: Drebrin-like protein; n=3; Coelomata|Re... 55 1e-05 UniRef50_A7SKW6 Cluster: Predicted protein; n=1; Nematostella ve... 54 2e-05 UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 54 2e-05 UniRef50_Q5ZLR6 Cluster: Rho guanine nucleotide exchange factor ... 54 2e-05 UniRef50_UPI00015A4B5A Cluster: protein tyrosine phosphatase, no... 54 2e-05 UniRef50_A1YTM4 Cluster: Intersectin; n=1; Lampetra fluviatilis|... 54 2e-05 UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 54 2e-05 UniRef50_Q7K137 Cluster: LD10453p; n=4; Diptera|Rep: LD10453p - ... 54 2e-05 UniRef50_Q5T4P1 Cluster: Phosphoinositide-3-kinase, regulatory s... 54 2e-05 UniRef50_Q9D7V1 Cluster: SH2 domain-containing protein 4A; n=4; ... 54 2e-05 UniRef50_Q9H788 Cluster: SH2 domain-containing protein 4A (Prote... 54 2e-05 UniRef50_UPI0000D562ED Cluster: PREDICTED: similar to growth fac... 54 3e-05 UniRef50_UPI00004D6B5A Cluster: SH2B adapter protein 3 (Lymphocy... 54 3e-05 UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 54 3e-05 UniRef50_Q5DAS3 Cluster: SJCHGC02119 protein; n=1; Schistosoma j... 54 3e-05 UniRef50_Q4PAN1 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-05 UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int... 54 3e-05 UniRef50_Q14155 Cluster: Rho guanine nucleotide exchange factor ... 54 3e-05 UniRef50_UPI0000D9C236 Cluster: PREDICTED: abl-interactor 1 isof... 53 4e-05 UniRef50_UPI000051AA4C Cluster: PREDICTED: similar to rho-type g... 53 4e-05 UniRef50_A7RXM7 Cluster: Predicted protein; n=1; Nematostella ve... 53 4e-05 UniRef50_Q59G41 Cluster: Abl-interactor 1 variant; n=46; Eumetaz... 53 4e-05 UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 53 4e-05 UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 53 4e-05 UniRef50_UPI000065F8ED Cluster: SH3-containing GRB2-like protein... 53 5e-05 UniRef50_Q4SCY6 Cluster: Chromosome 14 SCAF14646, whole genome s... 53 5e-05 UniRef50_Q4S131 Cluster: Chromosome 1 SCAF14770, whole genome sh... 53 5e-05 UniRef50_Q59PV2 Cluster: Putative uncharacterized protein; n=3; ... 53 5e-05 UniRef50_Q9JID9 Cluster: SH2B adapter protein 2; n=16; Euteleost... 53 5e-05 UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 53 5e-05 UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 52 7e-05 UniRef50_UPI00006CBE11 Cluster: C2 domain containing protein; n=... 52 7e-05 UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 52 7e-05 UniRef50_Q4S5H4 Cluster: Chromosome 3 SCAF14730, whole genome sh... 52 7e-05 UniRef50_Q556K1 Cluster: Putative uncharacterized protein; n=2; ... 52 7e-05 UniRef50_A0NFK4 Cluster: ENSANGP00000030373; n=2; Coelomata|Rep:... 52 7e-05 UniRef50_Q9NZM3 Cluster: Intersectin-2; n=40; Euteleostomi|Rep: ... 52 7e-05 UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 52 7e-05 UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 52 7e-05 UniRef50_UPI000155BC71 Cluster: PREDICTED: similar to inositol p... 52 1e-04 UniRef50_UPI0000D554A0 Cluster: PREDICTED: similar to CG11146-PA... 52 1e-04 UniRef50_Q4RNX3 Cluster: Chromosome 10 SCAF15009, whole genome s... 52 1e-04 UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 52 1e-04 UniRef50_Q7QG48 Cluster: ENSANGP00000010943; n=1; Anopheles gamb... 52 1e-04 UniRef50_P10569 Cluster: Myosin IC heavy chain; n=4; Eukaryota|R... 52 1e-04 UniRef50_Q6BNP6 Cluster: Class E vacuolar protein-sorting machin... 52 1e-04 UniRef50_Q5A895 Cluster: Class E vacuolar protein-sorting machin... 52 1e-04 UniRef50_UPI0000E47242 Cluster: PREDICTED: hypothetical protein;... 52 1e-04 UniRef50_UPI00015A3F46 Cluster: UPI00015A3F46 related cluster; n... 52 1e-04 UniRef50_UPI000065D63E Cluster: Hematopoietic lineage cell-speci... 52 1e-04 UniRef50_Q98TP5 Cluster: C-Src protein-tyrosine kinase; n=5; Eut... 52 1e-04 UniRef50_Q4S0P4 Cluster: Chromosome 2 SCAF14781, whole genome sh... 52 1e-04 UniRef50_Q9VIN1 Cluster: CG10043-PA, isoform A; n=6; Diptera|Rep... 52 1e-04 UniRef50_Q9VIF7 Cluster: CG1099-PA, isoform A; n=8; Sophophora|R... 52 1e-04 UniRef50_Q6T3S4 Cluster: AbpE; n=4; Dictyostelium discoideum|Rep... 52 1e-04 UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 52 1e-04 UniRef50_Q96HU1 Cluster: RUN and TBC1 domain containing 3; n=34;... 52 1e-04 UniRef50_Q7Z709 Cluster: RUN and TBC1 domain-containing protein ... 52 1e-04 UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 52 1e-04 UniRef50_O15357 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 52 1e-04 UniRef50_Q8CBW3 Cluster: Abl interactor 1; n=74; Euteleostomi|Re... 52 1e-04 UniRef50_UPI0000E498C8 Cluster: PREDICTED: similar to SH3-domain... 51 2e-04 UniRef50_UPI0000E47DD5 Cluster: PREDICTED: similar to endophilin... 51 2e-04 UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 51 2e-04 UniRef50_UPI00005A0859 Cluster: PREDICTED: similar to SH2 domain... 51 2e-04 UniRef50_Q4SIP6 Cluster: Chromosome 21 SCAF14577, whole genome s... 51 2e-04 UniRef50_Q5DBN4 Cluster: SJCHGC05332 protein; n=1; Schistosoma j... 51 2e-04 UniRef50_A7S0K6 Cluster: Predicted protein; n=1; Nematostella ve... 51 2e-04 UniRef50_Q7M4L6 Cluster: Shb-like adapter protein, Shf; n=21; Am... 51 2e-04 UniRef50_A5DS28 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-04 UniRef50_Q2I6J0 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 51 2e-04 UniRef50_Q15464 Cluster: SH2 domain-containing adapter protein B... 51 2e-04 UniRef50_UPI00015B47B7 Cluster: PREDICTED: similar to ENSANGP000... 51 2e-04 UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti... 51 2e-04 UniRef50_UPI00006CBE10 Cluster: conserved hypothetical protein; ... 51 2e-04 UniRef50_Q7PWA1 Cluster: ENSANGP00000005190; n=2; Culicidae|Rep:... 51 2e-04 UniRef50_Q400L7 Cluster: Putative uncharacterized protein; n=4; ... 51 2e-04 UniRef50_A6QS61 Cluster: Predicted protein; n=1; Ajellomyces cap... 51 2e-04 UniRef50_A5DTH4 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-04 UniRef50_Q8N157 Cluster: Jouberin; n=40; Eumetazoa|Rep: Jouberin... 51 2e-04 UniRef50_UPI00015B4161 Cluster: PREDICTED: hypothetical protein;... 50 3e-04 UniRef50_UPI0000E4A632 Cluster: PREDICTED: similar to Syt7 prote... 50 3e-04 UniRef50_UPI000069E2B7 Cluster: UPI000069E2B7 related cluster; n... 50 3e-04 UniRef50_UPI000065F386 Cluster: Homolog of Homo sapiens "Interse... 50 3e-04 UniRef50_Q7T0U4 Cluster: MGC68984 protein; n=2; Xenopus|Rep: MGC... 50 3e-04 UniRef50_O08635 Cluster: SH3 domain protein D19; n=17; Tetrapoda... 50 3e-04 UniRef50_A2AQ87 Cluster: Novel protein (Possible orthologue of h... 50 3e-04 UniRef50_Q9TYT3 Cluster: Putative uncharacterized protein; n=5; ... 50 3e-04 UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 50 3e-04 UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 50 3e-04 UniRef50_O18683 Cluster: P60 protein; n=2; Sophophora|Rep: P60 p... 50 3e-04 UniRef50_A7SJB4 Cluster: Predicted protein; n=1; Nematostella ve... 50 3e-04 UniRef50_Q5SQS7 Cluster: Novel SH2 domain-containing protein; n=... 50 3e-04 UniRef50_Q0UD52 Cluster: Putative uncharacterized protein; n=1; ... 50 3e-04 UniRef50_P98077 Cluster: SHC-transforming protein 2; n=15; Tetra... 50 3e-04 UniRef50_Q13094 Cluster: Lymphocyte cytosolic protein 2; n=31; A... 50 3e-04 UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 50 3e-04 UniRef50_UPI00015B564A Cluster: PREDICTED: similar to CRK protei... 50 4e-04 UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 50 4e-04 UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 50 4e-04 UniRef50_Q4RUJ4 Cluster: Chromosome 1 SCAF14995, whole genome sh... 50 4e-04 UniRef50_Q5BXE8 Cluster: SJCHGC01829 protein; n=3; Schistosoma j... 50 4e-04 UniRef50_Q45FX5 Cluster: Protein vav-1; n=4; Caenorhabditis|Rep:... 50 4e-04 UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 50 4e-04 UniRef50_Q9NYB9 Cluster: Abl interactor 2; n=103; Euteleostomi|R... 50 4e-04 UniRef50_UPI0000E81EFA Cluster: PREDICTED: hypothetical protein;... 50 5e-04 UniRef50_UPI0000ECBBF3 Cluster: Drebrin-like protein (SH3 domain... 50 5e-04 UniRef50_Q4R4C1 Cluster: Testis cDNA clone: QtsA-11117, similar ... 50 5e-04 UniRef50_Q5DEG7 Cluster: SJCHGC01831 protein; n=1; Schistosoma j... 50 5e-04 UniRef50_A7S295 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-04 UniRef50_A7RQF8 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-04 UniRef50_Q92835 Cluster: Phosphatidylinositol-3,4,5-trisphosphat... 50 5e-04 UniRef50_P34416 Cluster: LIM and SH3 domain protein F42H10.3; n=... 50 5e-04 UniRef50_P38753 Cluster: Class E vacuolar protein-sorting machin... 50 5e-04 UniRef50_O94868 Cluster: FCH and double SH3 domains protein 2; n... 50 5e-04 UniRef50_UPI00015B4F0B Cluster: PREDICTED: similar to Jak pathwa... 49 7e-04 UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,... 49 7e-04 UniRef50_Q6PBV3 Cluster: Zgc:73230; n=2; Danio rerio|Rep: Zgc:73... 49 7e-04 UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 49 7e-04 UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 49 7e-04 UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 49 7e-04 UniRef50_Q54DN5 Cluster: SH3 domain-containing protein; n=2; Dic... 49 7e-04 UniRef50_A7T185 Cluster: Predicted protein; n=1; Nematostella ve... 49 7e-04 UniRef50_Q6C963 Cluster: Yarrowia lipolytica chromosome D of str... 49 7e-04 UniRef50_Q2H2P1 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-04 UniRef50_A6R7Z9 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-04 UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 49 7e-04 UniRef50_Q75DS3 Cluster: Class E vacuolar protein-sorting machin... 49 7e-04 UniRef50_UPI0001555A82 Cluster: PREDICTED: similar to Cortactin,... 49 9e-04 UniRef50_UPI0000F207BA Cluster: PREDICTED: hypothetical protein;... 49 9e-04 UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 49 9e-04 UniRef50_UPI0000E483A8 Cluster: PREDICTED: similar to plenty of ... 49 9e-04 UniRef50_UPI0000519A8B Cluster: PREDICTED: similar to Phosphatid... 49 9e-04 UniRef50_UPI00004D5D63 Cluster: Jouberin (Abelson helper integra... 49 9e-04 UniRef50_UPI000065EFEA Cluster: Growth factor receptor-bound pro... 49 9e-04 UniRef50_Q4V9Q1 Cluster: Zgc:109892; n=11; Euteleostomi|Rep: Zgc... 49 9e-04 UniRef50_Q4RMS9 Cluster: Chromosome 3 SCAF15018, whole genome sh... 49 9e-04 UniRef50_Q5U3B8 Cluster: SH3D19 protein; n=24; Amniota|Rep: SH3D... 49 9e-04 UniRef50_Q9UNF0 Cluster: Protein kinase C and casein kinase subs... 49 9e-04 UniRef50_UPI0000E4836F Cluster: PREDICTED: hypothetical protein;... 48 0.001 UniRef50_UPI00006A0BC0 Cluster: Growth factor receptor-bound pro... 48 0.001 UniRef50_Q4RIB1 Cluster: Chromosome 8 SCAF15044, whole genome sh... 48 0.001 UniRef50_Q32LS7 Cluster: Zgc:123285; n=2; Danio rerio|Rep: Zgc:1... 48 0.001 UniRef50_Q9XTL2 Cluster: CG6521-PA; n=2; Sophophora|Rep: CG6521-... 48 0.001 UniRef50_Q8MML2 Cluster: SYNAPTIC DYNAMIN-ASSOCIATED PROTEIN IIB... 48 0.001 UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 48 0.001 UniRef50_Q5T185 Cluster: SHC (Src homology 2 domain containing) ... 48 0.001 UniRef50_P29353 Cluster: SHC-transforming protein 1; n=46; Tetra... 48 0.001 UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 48 0.001 UniRef50_Q10199 Cluster: Septation protein imp2; n=1; Schizosacc... 48 0.001 UniRef50_Q6VYH9 Cluster: Hematopoietic SH2 domain-containing pro... 48 0.001 UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 48 0.001 UniRef50_UPI00015B496D Cluster: PREDICTED: similar to conserved ... 48 0.002 UniRef50_UPI0000E4625F Cluster: PREDICTED: hypothetical protein;... 48 0.002 UniRef50_UPI0000DB713D Cluster: PREDICTED: similar to CG11146-PA... 48 0.002 UniRef50_UPI00015A7910 Cluster: hypothetical protein LOC553596; ... 48 0.002 UniRef50_UPI000066017A Cluster: nitric oxide synthase traffickin... 48 0.002 UniRef50_Q1ED32 Cluster: Zgc:136231; n=1; Danio rerio|Rep: Zgc:1... 48 0.002 UniRef50_Q75JD4 Cluster: Similar to Xenopus laevis (African claw... 48 0.002 UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 48 0.002 UniRef50_Q5BXT3 Cluster: SJCHGC03955 protein; n=1; Schistosoma j... 48 0.002 UniRef50_Q2H8X6 Cluster: Putative uncharacterized protein; n=1; ... 48 0.002 UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 48 0.002 UniRef50_Q6CVA8 Cluster: Class E vacuolar protein-sorting machin... 48 0.002 UniRef50_UPI000051A29D Cluster: PREDICTED: similar to SHC-adapto... 48 0.002 UniRef50_UPI000065FE19 Cluster: SHC-transforming protein 1 (SH2 ... 48 0.002 UniRef50_Q4SM05 Cluster: Chromosome 13 SCAF14555, whole genome s... 48 0.002 UniRef50_A1L2S0 Cluster: LOC100036932 protein; n=3; Xenopus|Rep:... 48 0.002 UniRef50_A1L2D2 Cluster: Zgc:158798; n=7; Clupeocephala|Rep: Zgc... 48 0.002 UniRef50_Q9VA36 Cluster: CG31012-PC, isoform C; n=9; Sophophora|... 48 0.002 UniRef50_Q9BHE8 Cluster: C2 domain protein; n=2; Leishmania|Rep:... 48 0.002 UniRef50_Q8T7Z1 Cluster: Mlk (Mixed lineage kinase) homolog prot... 48 0.002 UniRef50_Q8T7Z0 Cluster: Mlk (Mixed lineage kinase) homolog prot... 48 0.002 UniRef50_Q21430 Cluster: Putative uncharacterized protein pix-1;... 48 0.002 UniRef50_A0BND2 Cluster: Chromosome undetermined scaffold_118, w... 48 0.002 UniRef50_Q6CD36 Cluster: Similar to sp|P53281 Saccharomyces cere... 48 0.002 UniRef50_Q6BK14 Cluster: Similar to sp|P47068 Saccharomyces cere... 48 0.002 UniRef50_Q5K6X7 Cluster: Cell division control protein 25, putat... 48 0.002 UniRef50_Q4P3H3 Cluster: Putative uncharacterized protein; n=1; ... 48 0.002 UniRef50_A6REM5 Cluster: Predicted protein; n=1; Ajellomyces cap... 48 0.002 UniRef50_P39743 Cluster: Reduced viability upon starvation prote... 48 0.002 UniRef50_Q4P5J4 Cluster: Class E vacuolar protein-sorting machin... 48 0.002 UniRef50_UPI0000E465C3 Cluster: PREDICTED: hypothetical protein;... 47 0.003 UniRef50_UPI00015A6A53 Cluster: hypothetical protein LOC406311; ... 47 0.003 UniRef50_UPI000065F097 Cluster: Hematopoietic SH2 domain-contain... 47 0.003 UniRef50_UPI0000ECA839 Cluster: UPI0000ECA839 related cluster; n... 47 0.003 UniRef50_Q13322-2 Cluster: Isoform 1 of Q13322 ; n=5; Homo/Pan/G... 47 0.003 UniRef50_Q4SYA1 Cluster: Chromosome undetermined SCAF12132, whol... 47 0.003 UniRef50_Q4RP74 Cluster: Chromosome 1 SCAF15008, whole genome sh... 47 0.003 UniRef50_Q5C288 Cluster: SJCHGC09127 protein; n=1; Schistosoma j... 47 0.003 UniRef50_A7SAV1 Cluster: Predicted protein; n=1; Nematostella ve... 47 0.003 UniRef50_Q1DZA2 Cluster: Putative uncharacterized protein; n=1; ... 47 0.003 UniRef50_Q5VZ18 Cluster: SH2 domain-containing adapter protein E... 47 0.003 UniRef50_O00459 Cluster: Phosphatidylinositol 3-kinase regulator... 47 0.003 UniRef50_Q13322 Cluster: Growth factor receptor-bound protein 10... 47 0.003 UniRef50_UPI0000E45D4F Cluster: PREDICTED: similar to SH2 domain... 47 0.004 UniRef50_UPI00006CA823 Cluster: Variant SH3 domain containing pr... 47 0.004 UniRef50_UPI00006A1C31 Cluster: UPI00006A1C31 related cluster; n... 47 0.004 UniRef50_UPI00006A1C30 Cluster: UPI00006A1C30 related cluster; n... 47 0.004 UniRef50_Q6GP30 Cluster: MGC80721 protein; n=1; Xenopus laevis|R... 47 0.004 UniRef50_Q6DBQ9 Cluster: Zgc:91999; n=7; Danio rerio|Rep: Zgc:91... 47 0.004 UniRef50_Q4SID9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 47 0.004 UniRef50_Q4RZ53 Cluster: Chromosome 7 SCAF14966, whole genome sh... 47 0.004 UniRef50_Q07DM1 Cluster: Ahi1; n=2; Danio rerio|Rep: Ahi1 - Dani... 47 0.004 UniRef50_Q5BWZ4 Cluster: SJCHGC04657 protein; n=1; Schistosoma j... 47 0.004 UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 47 0.004 UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 47 0.004 UniRef50_Q12965 Cluster: Myosin-Ie; n=48; Bilateria|Rep: Myosin-... 47 0.004 UniRef50_Q0U6X7 Cluster: Class E vacuolar protein-sorting machin... 47 0.004 UniRef50_UPI00015B5DE3 Cluster: PREDICTED: hypothetical protein;... 46 0.005 UniRef50_UPI00015A734B Cluster: SH3 multiple domains 2 like; n=1... 46 0.005 UniRef50_A5D8S5 Cluster: Si:dkey-15j16.4 protein; n=10; Euteleos... 46 0.005 UniRef50_Q17PR7 Cluster: Putative uncharacterized protein; n=1; ... 46 0.005 UniRef50_Q17IU1 Cluster: Signal transducing adapter molecule; n=... 46 0.005 UniRef50_A7T2F6 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 46 0.005 >UniRef50_UPI0000D57912 Cluster: PREDICTED: similar to CG4200-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4200-PA - Tribolium castaneum Length = 1233 Score = 1552 bits (3848), Expect = 0.0 Identities = 704/1194 (58%), Positives = 918/1194 (76%), Gaps = 17/1194 (1%) Query: 14 IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73 I E +Q+IS +ERG+ V+K+ RK+ E + L +RRET Q++W+R + ++GA+D+R Sbjct: 39 IPEMEQIISQLERGTLVMKYSLRKKAEHKTLAIRRETRQIVWTRPATNSKPVHDGAVDLR 98 Query: 74 DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133 +KE+R GKSSKDF++W +++K++E+ KCF +YYG+EFKLR S A ++KECE WVKG+ Sbjct: 99 KIKEIRLGKSSKDFDKWADDSKKIENLKCFVVYYGSEFKLRVLSIAALSEKECELWVKGL 158 Query: 134 LYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQ 193 YL+ + ++ YPLQ++ WLR+EFY++EN E I +K++KAFLP+IN KI T+KLR++F Sbjct: 159 RYLVKDTINVPYPLQVQVWLRREFYAMENPTETINIKDLKAFLPRINYKIPTNKLRELFN 218 Query: 194 DVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQH 253 +VDT KR EIGFDDFAVLYQK+IFDE+N +IFDK ++Y SN +++L+E Q+FL EQ+ Sbjct: 219 EVDTRKRAEIGFDDFAVLYQKIIFDESNGAEIFDKLALYSSNLKSVSLQEVQSFLAKEQN 278 Query: 254 DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313 D+L +D+ S+FI D+L+DPQR++ EP+FT+SEF++ L+SKQN ++D D V QDM++ Sbjct: 279 DDLSNDDRAVSRFICDFLKDPQREVQEPHFTISEFLDYLFSKQNDLWDPNKDSVHQDMSK 338 Query: 314 PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373 PLSHYWI+SSHNTYLTGDQ SSESS+EAY RCLR GCRCIELDCWDGPDG PFIYHGHT Sbjct: 339 PLSHYWIASSHNTYLTGDQLSSESSVEAYARCLRMGCRCIELDCWDGPDGMPFIYHGHTF 398 Query: 374 TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433 TTKI+FMDV++TIKEHAF TSEYP+ILSIEDNCSLPQQR+MA+A Q+VFG+ LL HP++K Sbjct: 399 TTKIKFMDVIKTIKEHAFATSEYPVILSIEDNCSLPQQRKMATAMQEVFGESLLTHPVEK 458 Query: 434 NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDK 493 NE LPSP+ PEG +ESS + + EG ++DLR+S +NGI++LEDPVDK Sbjct: 459 NEKQLPSPYQLRRRIILKHKKLPEGQDESSSILIRHEGSEMDLRSSFRNGIMYLEDPVDK 518 Query: 494 EWKPHAFVLTENKLYYTESY-----NSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHG 548 EW PH FVLTENKL+YT+SY + + + VP +ELHF+E WFHG Sbjct: 519 EWNPHFFVLTENKLFYTDSYKPDQESERSEDEDDSAAAFHRSKSDVPNEELHFSEKWFHG 578 Query: 549 KLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVT 608 KLA R+EAE LL+A++HLGDGTFLVR SVTFVG+YCLSFWR G+VNHCRI+ K ++ T Sbjct: 579 KLANGREEAEQLLKAYSHLGDGTFLVRASVTFVGEYCLSFWRNGQVNHCRIRSKPDKQHT 638 Query: 609 KFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAE 668 ++YL D+ FDSLY+LITHYR+ PL + EF ITL+EPVPQP KHE +EW+H H + QA+ Sbjct: 639 RYYLTDAKYFDSLYSLITHYRNCPLVTAEFSITLQEPVPQPKKHETEEWYHKHTGKMQAD 698 Query: 669 ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELV 728 E+LR+ +GAFLVRPSE + + ISFR +K+IKHCR+K EGRLYTIG V+FESL+EL+ Sbjct: 699 EILRRVKMEGAFLVRPSENDANCYTISFRADKKIKHCRIKLEGRLYTIGNVEFESLVELI 758 Query: 729 SYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVY-GTPGYMDPTSFT-SKVTVKALYD 786 +YYENHPLY++VKL YPISEE V+R+ + DDN Y +P YMDP++FT K+TVKALYD Sbjct: 759 NYYENHPLYRRVKLSYPISEEAVKRMTMQ-DDNVGYNSSPSYMDPSAFTPPKITVKALYD 817 Query: 787 YRARQDDELSFCKHAIITNVDKPDE--GWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTS 844 YRA+Q DELSFCKHAIITNV KP+ GWWRGDYGG + H+FPANYV+E++ + D Sbjct: 818 YRAQQPDELSFCKHAIITNVTKPENSPGWWRGDYGGMKQHFFPANYVMELDRMESQD--- 874 Query: 845 GLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATRESA 904 G ++ S S+ +G LD+ GA+V+L+ W+V++ + +P ++A +RE A Sbjct: 875 GSDDGSGE--SMLQGQLDMNGAVVDLIHHPERPGLEWVVKIVTSTACTPLEVALQSREMA 932 Query: 905 LEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNE 964 +EW +MERT+RIAKE+S+LIIYCRS+TFNIER R +GF++ E Sbjct: 933 VEWMLAIKEVAQRACALENHHREMERTFRIAKEMSNLIIYCRSITFNIERARQQGFIFYE 992 Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 MSSFPETKAE+LM QQE FFVKYH Q SR+YPKGQR+DSSNYNP+ WN GSQMVALN Sbjct: 993 MSSFPETKAEKLMCQQEKKFFVKYHQHQFSRVYPKGQRVDSSNYNPINMWNIGSQMVALN 1052 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084 YQT DKPMQ+N KF+ NG CG++LKP FMF + ++P D+ ++ G V+P V LR+I AR Sbjct: 1053 YQTGDKPMQLNQAKFRDNGNCGYLLKPDFMFRDDFDPADRNTLVG-VEPWIVTLRIIAAR 1111 Query: 1085 HLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW-NDICEFEVANPELALI 1143 HL + +GTASPFVEVE+IGA +DSG KL TK V+DNG NP W ++ EF V NP AL+ Sbjct: 1112 HLFRPKKGTASPFVEVEVIGAPFDSGTKLSTKPVTDNGFNPRWMEEVIEFPVYNPYFALL 1171 Query: 1144 RFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 RFVVQDED+FGEPNFIGQAT+P+ CLR GYRSV L NA+SE+LEL++L++H+SI Sbjct: 1172 RFVVQDEDVFGEPNFIGQATYPVTCLRTGYRSVWLKNAYSEDLELASLLIHISI 1225 >UniRef50_Q7QHE3 Cluster: ENSANGP00000022029; n=2; Anopheles gambiae str. PEST|Rep: ENSANGP00000022029 - Anopheles gambiae str. PEST Length = 1230 Score = 1438 bits (3563), Expect = 0.0 Identities = 682/1213 (56%), Positives = 866/1213 (71%), Gaps = 37/1213 (3%) Query: 16 EADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDV 75 E +Q+I +ERG+ + KF+PRKRPE++ L +RRET Q++WS + R YEG+L++R+V Sbjct: 18 EMEQIICQLERGTLIQKFYPRKRPEKKTLMLRRETRQIIWSSVQTNGRSNYEGSLELREV 77 Query: 76 KEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLY 135 KEVR GK SKDFE+WPEE K+ E KCF I +G +FKLR S VA ++KE + W+KG+ Y Sbjct: 78 KEVRPGKKSKDFEKWPEEAKKSEPRKCFVILHGNDFKLRTVSIVAFSEKEADMWLKGLKY 137 Query: 136 LIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV 195 LI++ VSA Y LQIERWLR+EFY +E ++ +LK+V++FLPKINCKIST+KL +VF +V Sbjct: 138 LISDTVSAPYWLQIERWLRREFYLME-ANGTASLKDVRSFLPKINCKISTAKLNEVFHEV 196 Query: 196 DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFD--KYSVYCSNGTTITLREFQNFLRDEQH 253 DT +R E+GFDDF LYQ+LI ++ + FD + + Y NG T+TL+EF+ FL EQ Sbjct: 197 DTRRRNELGFDDFTRLYQRLILPPASLPEYFDGLRMATYSQNGETVTLQEFRRFLTKEQQ 256 Query: 254 DNLGD-----DEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308 ++ G E ++FI DY++DP RD+ EPY L EF++ L+S+QN I+D + D V Sbjct: 257 EDEGSPGGGHSEETVAKFINDYIQDPARDVSEPYLRLHEFIDFLFSRQNEIWDKRCDTVY 316 Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 QDM+RPL+HYWISSSHNTYLTGDQFSSESS+EAY R LR GCRCIELDCWDGPD P I+ Sbjct: 317 QDMSRPLAHYWISSSHNTYLTGDQFSSESSVEAYARALRMGCRCIELDCWDGPDNMPLIF 376 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 HGHT TT+I+FMDV+RTIKEHAFITSEYPLILSIE NCSL QQRRMA A +VFG++LL Sbjct: 377 HGHTFTTRIKFMDVIRTIKEHAFITSEYPLILSIEQNCSLTQQRRMAQAMLEVFGEMLLT 436 Query: 429 HPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--------EESSFAVRQEEGKDLDLRNSI 480 P+DK E LPSP PE +ES+ +R + +LD+RN++ Sbjct: 437 QPIDKAEAQLPSPQQLKRKIILKHKKLPENGMLVVDEAGKESAVLMRGNDESELDIRNTV 496 Query: 481 KNGILHLEDPVDKEWKPHAFVLTENKLYYTESY---------NSQXXXXXXXXXXXXXXN 531 KNGIL+LEDPVDK W H FVLT++KL+YT+S + + Sbjct: 497 KNGILYLEDPVDKGWNAHFFVLTQHKLFYTDSQRPDRDADGRDDEREENGFATNRQSRDG 556 Query: 532 AIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ 591 A++ DELHF E WFHGKL+G R+EAE LL+ +HLGDGTFLVRESVTFVGDYCLSFWRQ Sbjct: 557 AVLSNDELHFGENWFHGKLSGGREEAEKLLQQFSHLGDGTFLVRESVTFVGDYCLSFWRQ 616 Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNK 651 GK NHCRIKLKQ++GVTK+YL++++ F+SLY+LI +YR + LRS EF ITLKEPVPQPNK Sbjct: 617 GKPNHCRIKLKQDKGVTKYYLMENVLFESLYSLIMYYRQNALRSAEFYITLKEPVPQPNK 676 Query: 652 HEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEG 711 HE KEW+H TR Q+E +L + DGAFLVRPSEK +F ISFR + KHCR++ EG Sbjct: 677 HETKEWYHQTTTREQSEIVLNQIPQDGAFLVRPSEKGTKAFVISFRAHGKFKHCRIRVEG 736 Query: 712 RLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL----VS-EPDDNTVYGT 766 RLY +G ++FESL++LV++Y HPLY+KV L YPI E +RR+ VS P G Sbjct: 737 RLYEMGGMEFESLVDLVNFYSKHPLYRKVTLTYPIPREMIRRINTMDVSCGPPVPEESGG 796 Query: 767 PGYMDPTSFTSK-VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHW 825 GYMDP + T++ VTVKALYDY+A++DDELSFCKHAIITNV K WW GDYGGKR H+ Sbjct: 797 YGYMDPATVTNENVTVKALYDYKAQRDDELSFCKHAIITNVVKRGNDWWLGDYGGKRQHY 856 Query: 826 FPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRV 885 FPANYV E+ + NE LGSLQKG LDV GA+VE+ + R ++R+ Sbjct: 857 FPANYVQELSAMDDGTLVEEGANEPLMLGSLQKGSLDVHGAVVEMAYSNHPDIER-ILRI 915 Query: 886 QSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYC 945 Q+P M + F++ T+E A EW KMER R+AKE+SDLIIYC Sbjct: 916 QNPTMQNVFEVGVQTKELAYEWMCAIKEAAQNASAMENERRKMERNSRVAKEMSDLIIYC 975 Query: 946 RSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQE-NTFFVKYHTTQLSRIYPKGQRID 1004 RSV F + +V+ EMSSFPETKAE+ Q E FV+YH LSR+YPKGQR+D Sbjct: 976 RSVPF---KHHPAAWVFYEMSSFPETKAEKYFLQAETRALFVRYHRNHLSRVYPKGQRLD 1032 Query: 1005 SSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK 1064 SSNY+P WNCGSQM+ALN+QTPDKPMQ+N KF+ NGGCG++LKP+FMF + ++P D Sbjct: 1033 SSNYHPTALWNCGSQMIALNFQTPDKPMQLNQAKFRDNGGCGYLLKPEFMFRDEFDPTDP 1092 Query: 1065 KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLN 1124 ++ G V V V +R+IG R+LCK R SP VEVE++GA +D G+K T+ ++DNGLN Sbjct: 1093 NTLVG-VGEVIVNVRIIGGRNLCKVSRNITSPLVEVEVLGASFDGGIKHRTRAIADNGLN 1151 Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184 P+WN+ICEF +ANP A+IRF VQDED+FGEPNFIGQA FPL +R GYRSV L N +SE Sbjct: 1152 PIWNEICEFRIANPHFAMIRFEVQDEDMFGEPNFIGQAVFPLGSIRTGYRSVVLRNKYSE 1211 Query: 1185 ELELSTLMVHLSI 1197 ELEL+TL+VH SI Sbjct: 1212 ELELATLLVHTSI 1224 >UniRef50_A2IB48 Cluster: Phospholipase C gamma; n=5; Eumetazoa|Rep: Phospholipase C gamma - Chaetopterus pergamentaceus Length = 1322 Score = 1272 bits (3150), Expect = 0.0 Identities = 612/1196 (51%), Positives = 835/1196 (69%), Gaps = 40/1196 (3%) Query: 20 LISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVR 79 ++ +ERG KF+P+KRPE+R V+ ET Q++W R N R EG +D R++KEVR Sbjct: 28 MLRLLERGCVFTKFYPKKRPEKRTFQVKLETRQLIWIR-NQGGRA--EGTVDFREIKEVR 84 Query: 80 TGKSSKDFER-WPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA 138 G +S+DFE+ PE+ ++L+ CF + YG++F+L+ S A + +E W+ G+ +L+ Sbjct: 85 PGTNSRDFEKLMPEDARKLDPLLCFVVLYGSQFRLKTLSVAAVSPEEYNLWMTGLKFLVE 144 Query: 139 EAVSASYPLQIERWLRKEFYSIEN----SHEK-----ITLKEVKAFLPKINCKISTSKLR 189 SA YPLQ+ERWL KEF ++ S +K +TLK++K++LP+IN KI +KLR Sbjct: 145 NTQSAPYPLQVERWLWKEFNMMDTRAGVSSQKDREITVTLKDIKSWLPRINLKIPNNKLR 204 Query: 190 DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY-SVYCSNGTTITLREFQNFL 248 + +Q +DT + +IGF F++LY+ L++ V +FD+Y Y SNG IT +F NFL Sbjct: 205 EKYQRIDTNCK-DIGFVAFSLLYRDLVY----VPTVFDRYFGGYMSNGENITAEDFLNFL 259 Query: 249 RDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308 + E+ D D Q + +L D R + P+FT EF++ ++S++N+I++ +D VT Sbjct: 260 KSEEKDTSVDTVRTVEQLMLQFLDDQMRAV-RPFFTPQEFMDWMFSEENTIWNKAFDAVT 318 Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 QDM +PLS+YWI+SSHNTYLT +Q+SSESS EAY R L+ GCRCIELDCWDGPD P IY Sbjct: 319 QDMDQPLSYYWIASSHNTYLTENQYSSESSTEAYARVLQMGCRCIELDCWDGPDNLPHIY 378 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 HGHTLT+KIRFMDVL TIK +AF+ SEYP+ILSIE++CSL QQR MASAF++VFGD+LL+ Sbjct: 379 HGHTLTSKIRFMDVLYTIKANAFLVSEYPIILSIENHCSLLQQRNMASAFREVFGDMLLI 438 Query: 429 HPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVR----QEEGKDLDLRNSIKNGI 484 P+D NET LPSP+ P+G + + + + D DL NSIKN I Sbjct: 439 EPIDVNETVLPSPNQLKRRIILKHKKLPDGVDGTDWRMAGLADDMSVADGDLSNSIKNDI 498 Query: 485 LHLEDPVDKEWKPHAFVLTENKLYYTE--SYNSQXXXXXXXXXXXXXXNAIVPQDELHFA 542 L LEDP+DKEW PH FVLT++KL+YT+ + SQ + DE+HF+ Sbjct: 499 LFLEDPIDKEWHPHFFVLTQSKLHYTDETAVTSQEDEEEESNDTSLQLEGL-GNDEMHFS 557 Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602 E WFHGKL G R++AEDLL+ +++LGDGTFLVRES TFVGD+ LSFWR+ VNHCRI+ K Sbjct: 558 EKWFHGKLEGGRRKAEDLLKEYSYLGDGTFLVRESDTFVGDFSLSFWRKDSVNHCRIRSK 617 Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHC 662 QERG TK+YLID++ FDSLY+LITHY+ +PLRSQ+F LKEPVPQP H GK W+H Sbjct: 618 QERGQTKYYLIDNLAFDSLYSLITHYQKYPLRSQDFQQILKEPVPQPQSHHGKPWYHEKL 677 Query: 663 TRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFE 722 RT+AE++L++ +DGAFLVR + + S+AISFR E +IKHC +KQEGRL+TIG +FE Sbjct: 678 DRTRAEDMLKRIPSDGAFLVRQNGVDTNSYAISFRAEGKIKHCIIKQEGRLFTIGNAQFE 737 Query: 723 SLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPG-YMDPTSFTSKVTV 781 SL+ELV+YYE PLY+K+KL +P++E+ V+ + +PDD +YG PG YM+P FT K+ V Sbjct: 738 SLVELVNYYEKKPLYRKMKLKHPVNEKFVQSVGEDPDDTAIYGGPGIYMNPNDFTPKIHV 797 Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPD 841 +ALYDYRA+ +DELSFCK+AIITNV K DEGWW GD G ++ +FP+NYV EI D Sbjct: 798 RALYDYRAQMEDELSFCKNAIITNVIKRDEGWWLGDPGNQKRLYFPSNYVEEIR--SQDD 855 Query: 842 VTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATR 901 V ++S LG++QKG ++V G V+ ++ +G G ++ R+Q A P ++AA T Sbjct: 856 V-----SDSMPLGNMQKGTINVTGCAVDRIL-NGKGDKAYVFRIQHTANERPLEIAAETE 909 Query: 902 ESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFV 961 E L+W +E+ IAKE SDLI+YCRSV F E+ Sbjct: 910 EKMLDWMKNIRACANLAEEKVKKKHMIEKNKGIAKEFSDLIVYCRSVPFEPEKAPGN--- 966 Query: 962 YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021 Y +MSSFPETK E+ +++++ +KY+ QLSR+YPKG RIDSSNY+P PFWNCG M+ Sbjct: 967 YYDMSSFPETKGEKSLNRKDAAILMKYNKYQLSRVYPKGSRIDSSNYDPQPFWNCGCHML 1026 Query: 1022 ALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI 1081 ALNYQTPD+ MQ+N GKFK NG CG+IL+P+ M + +NP +K+ +EG V+P+++ + +I Sbjct: 1027 ALNYQTPDRSMQLNEGKFKLNGRCGYILQPECMHMDNFNPFNKRDLEGVVEPLSLSINII 1086 Query: 1082 GARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELA 1141 RHL KTGRG ASPFVEVEI+GA+YD K T TV DNGLNP+WN+ C+F++ NPE+A Sbjct: 1087 AGRHLVKTGRGIASPFVEVEIVGAEYDF-QKYKTSTVQDNGLNPVWNEQCDFDIINPEVA 1145 Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L+RFVVQD D+F +P+F+GQA FP+ CLR G+RSVPL N SE+LEL++L+VH+ + Sbjct: 1146 LLRFVVQDMDMFNDPHFMGQAVFPVKCLRSGFRSVPLKNGNSEDLELTSLLVHVEM 1201 >UniRef50_Q9VXH3 Cluster: CG4200-PA; n=5; Drosophila|Rep: CG4200-PA - Drosophila melanogaster (Fruit fly) Length = 1236 Score = 1150 bits (2848), Expect = 0.0 Identities = 588/1250 (47%), Positives = 793/1250 (63%), Gaps = 79/1250 (6%) Query: 5 CFNGAKDRLIHEADQLISYIERGSTVLKFFPR-KRPERRALCVRRETHQVLWSRI-NAPQ 62 CF+ L+ E +Q I +ERG+ V K + + +RP+RR L + RET Q+LW+ + Sbjct: 3 CFSAMSAPLLGEMEQTIGMLERGTIVTKLYGKQRRPDRRHLMLIRETRQLLWATVATQTP 62 Query: 63 RQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQT 122 R YEGA+ +R+++E+R GK SK+F + ++ +R ESSKCF I +G FKL+ S VA + Sbjct: 63 RTDYEGAIQLREIREIRVGKHSKEFRLFADDCQRFESSKCFVILHGNHFKLKSFSVVALS 122 Query: 123 DKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIEN-----------SHEKITLKE 171 + E + WV+G+ Y++ + + A YPLQI+RWLR+E+Y IEN S ++T+K+ Sbjct: 123 EIEADNWVRGLRYMVKDTLGAPYPLQIDRWLRREYYQIENVNTHSAKATEQSPAQVTIKD 182 Query: 172 VKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSV 231 K FL ++CK++T K + F + D ++ ++ FDDF+ LYQKL+ N + V Sbjct: 183 FKLFLAGVSCKMTTGKFMEHFTE-DVRRKHDLKFDDFSRLYQKLLLP-NGFASVLSGSGV 240 Query: 232 ----YCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQRDIYEPYFTL 285 Y + + E + FL EQ D + A+ FIRD+++D +RD+ EPY T Sbjct: 241 ANFPYSEDQQVVRPAELKQFLETEQRDVSASEISSAAIASFIRDFVQDVERDVQEPYLTF 300 Query: 286 SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345 EFV+ L+SKQN +++S+YD+V DM PLS YWI+SSHNTYLTGDQFSSESS EAY R Sbjct: 301 PEFVDFLFSKQNDLWNSKYDQVFMDMNLPLSSYWIASSHNTYLTGDQFSSESSCEAYARA 360 Query: 346 LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405 LR GCRCIELDCW+GPD P+I+HGHT+T+KI+FMDV++TIK+HAF +SEYP+ILSIE N Sbjct: 361 LRMGCRCIELDCWNGPDNLPYIFHGHTITSKIKFMDVIKTIKDHAFTSSEYPVILSIEQN 420 Query: 406 CSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEG------- 458 CSL QQR MA A +VFGD+LL P D+NE LPSP+ P+ Sbjct: 421 CSLEQQRNMAQALIEVFGDMLLTQPCDRNEQHLPSPYQLRRKIILKHKKLPQFDDIANGI 480 Query: 459 AEESSFAVRQE----------EGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLY 508 + S R E ++R K G+L+ +DPVDK W + FVLT +L Sbjct: 481 SSTGSLGHRSSLGGAGGGAHGENDGENVRKVFKEGLLYFKDPVDKSWNLYQFVLTHQELI 540 Query: 509 YT----ESYNSQXXXXXXXXXXXXXXNAIVPQ--------DELHFAECWFHGKLAGNRQE 556 Y+ ES N N+ + Q DELHF E WFHGKL G R+E Sbjct: 541 YSSEINESRNGNSEDDDFGLSSSCSLNSNMQQKQKDTSANDELHFGENWFHGKLEGGRKE 600 Query: 557 AEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSM 616 A+DLL+ + H GDGTFLVRES TFVGDY LSFWR+ + NHCRIKLK E G K+YL+++ Sbjct: 601 ADDLLKKYKHFGDGTFLVRESATFVGDYSLSFWRRNRPNHCRIKLKHENGSIKYYLVENF 660 Query: 617 CFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNT 676 FDSLY+LI +YR + LRS EF I LKEPVPQP KHE +EWFH + T+ QAE+ L + Sbjct: 661 VFDSLYSLIVYYRKNMLRSSEFSIILKEPVPQPKKHEDQEWFHPNTTKEQAEQGLYRLEI 720 Query: 677 DGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPL 736 G+FLVRPS + +F ISF ++IKHCR+ QEGRLY I T+ FESL+ L++YY +PL Sbjct: 721 -GSFLVRPSVQSINAFVISFTINRKIKHCRIMQEGRLYGIDTMNFESLVSLINYYTRNPL 779 Query: 737 YKKVKLWYPISEETVRRLVSEP---------DDNTVYGTPGYMDPTSFTSKVTVKALYDY 787 Y+ VKL +P+S+E +R+ ++E DDN G YM ++ VT KALY Y Sbjct: 780 YRNVKLSHPVSQELLRQALAEAAQGDHSGGHDDN---GASNYMG-SNLEENVTCKALYSY 835 Query: 788 RARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLE 847 +A + DELSF KHAIITNV + + WW GDYGG PANYV I+ T D S Sbjct: 836 KANKPDELSFPKHAIITNVQRDNSMWWIGDYGGMIKKHLPANYVKVID-STTEDYNS--L 892 Query: 848 NESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYSPFDMAAATRESALEW 907 NE G +++ GA+ L + G + +++Q+P M +PF + +E+A EW Sbjct: 893 NEEGTDGRTDS--IEIFGAVASLFESNDPGII-FKLQIQTPTMQNPFVIGFDNQETAYEW 949 Query: 908 XXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSS 967 K ERT R+AKE+SDLIIY RSV F R +++ EMSS Sbjct: 950 IKAIQEAALIASQLASERRKKERTARVAKEMSDLIIYFRSVPF-----REHSWIFQEMSS 1004 Query: 968 FPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQT 1027 FPETKAE+ QQ F+ YH Q+SR+YPKGQR+DSSN+NP+PFWN GSQM+ALNYQT Sbjct: 1005 FPETKAEKQFFQQNTQLFLSYHRNQISRVYPKGQRLDSSNFNPMPFWNVGSQMIALNYQT 1064 Query: 1028 PDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLC 1087 DK MQ+N KF+ NG CG+ILKP FM + +NP + +G + V V +R+I ARHL Sbjct: 1065 GDKAMQLNQAKFRNNGQCGYILKPSFMKSDSFNP-NNPLCDG-LSEVKVSIRLIAARHLF 1122 Query: 1088 KTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVV 1147 + G+ +P + VE+IGA +D+GVK TK V++NG NP+WN+ CEF V NP+ A++RF V Sbjct: 1123 RGGKSN-NPQIVVELIGASFDTGVKYRTK-VNENGFNPVWNESCEFNVRNPQFAILRFEV 1180 Query: 1148 QDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 QDED+F E +FI QA +PL C+R+GYRSV L N FSEELELS+L++++ I Sbjct: 1181 QDEDMFAETHFIAQACYPLTCIRQGYRSVILRNKFSEELELSSLLINIKI 1230 >UniRef50_P19174 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; n=65; Eumetazoa|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 - Homo sapiens (Human) Length = 1290 Score = 1141 bits (2826), Expect = 0.0 Identities = 587/1223 (47%), Positives = 795/1223 (65%), Gaps = 45/1223 (3%) Query: 3 SVCFNGAKDRLIHEAD--QLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRI 58 S C NG +A+ L +E G+ + F+ +K RPER+ V+ ET Q+ WSR Sbjct: 6 SPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSR- 64 Query: 59 NAPQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCAS 117 EGA+DIR++KE+R GK+S+DF+R+ E+ R + S CF I YG EF+L+ S Sbjct: 65 ---GADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTLS 121 Query: 118 FVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFL 176 A ++ E W+KG+ +L+ + + A PLQIERWLRK+FYS++ N ++I+ K++K L Sbjct: 122 LQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNML 181 Query: 177 PKINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI-FDKYSVYCS 234 ++N ++ + LR+ D++ ++ G+I + FA LY+ L++ D+ F + S + Sbjct: 182 SQVNYRVPNMRFLRERLTDLE-QRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA 240 Query: 235 NGTT----ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVE 290 ++L EFQ FL D Q + D +Q +F+ +LRDP R+I EPYF L EFV Sbjct: 241 GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT 300 Query: 291 MLYSKQNSIYDSQYDKVTQD-MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349 L+SK+NS+++SQ D V D M PLSHYWISSSHNTYLTGDQFSSESSLEAY RCLR G Sbjct: 301 FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG 360 Query: 350 CRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLP 409 CRCIELDCWDGPDG P IYHGHTLTTKI+F DVL TIKEHAF+ SEYP+ILSIED+CS+ Sbjct: 361 CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIA 420 Query: 410 QQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA--EESSFAVR 467 QQR MA F+ V GD LL P++ + LPSP+ EG+ EE ++ Sbjct: 421 QQRNMAQYFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM 480 Query: 468 QEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXX 527 E D+ NSIKNGIL+LEDPV+ EW PH FVLT +K+YY+E +S Sbjct: 481 YSEN---DISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSD-----QGNEDE 532 Query: 528 XXXNAIVPQDELHFAECWFHGKL-AG--NRQEAEDLLRAHA-HLG--DGTFLVRESVTFV 581 + ELH E WFHGKL AG R AE LL + G DG+FLVRES TFV Sbjct: 533 EEPKEVSSSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV 592 Query: 582 GDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLIT 641 GDY LSFWR GKV HCRI +Q+ G KF+L D++ FDSLY+LITHY+ PLR EF + Sbjct: 593 GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR 652 Query: 642 LKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701 L EPVPQ N HE KEW+HA TR QAE +L + DGAFLVR E S+AISFR E + Sbjct: 653 LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVR-KRNEPNSYAISFRAEGK 711 Query: 702 IKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDD 760 IKHCRV+QEG+ +G +F+SL++L+SYYE HPLY+K+KL YPI+EE + ++ +EPD Sbjct: 712 IKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDY 771 Query: 761 NTVY--GTPG-YMDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816 +Y PG Y++ T K VKAL+DY+A+++DEL+F K AII NV+K + GWWRG Sbjct: 772 GALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRG 831 Query: 817 DYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVEL-VVGDG 875 DYGGK+ WFP+NYV E+ P + +E++ LG L +GVLDV + + G Sbjct: 832 DYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKN 891 Query: 876 GGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIA 935 + + + S A +S D+AA ++E +W MER +IA Sbjct: 892 NRLFVFSISMASVAHWS-LDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIA 950 Query: 936 KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995 E+S+L++YCR V F+ E++ + Y +MSSFPETKAE+ +++ + F++Y+ QLSR Sbjct: 951 LELSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSR 1010 Query: 996 IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMF 1055 IYPKGQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N F CG++L+P M Sbjct: 1011 IYPKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMR 1070 Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115 +E ++P DK S+ G ++P + + V+GARHL K GRG PFVE+E+ GA+YDS K T Sbjct: 1071 DEAFDPFDKSSLRG-LEPCAISIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDS-TKQKT 1128 Query: 1116 KTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174 + V DNGLNP+W F+++NPE A +RFVV +ED+F + NF+ QATFP+ L+ GYR Sbjct: 1129 EFVVDNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYR 1188 Query: 1175 SVPLTNAFSEELELSTLMVHLSI 1197 +VPL N +SE+LEL++L++ + I Sbjct: 1189 AVPLKNNYSEDLELASLLIKIDI 1211 >UniRef50_O97034 Cluster: PLC-gammaS; n=1; Ephydatia fluviatilis|Rep: PLC-gammaS - Ephydatia fluviatilis Length = 1283 Score = 1078 bits (2670), Expect = 0.0 Identities = 562/1213 (46%), Positives = 758/1213 (62%), Gaps = 59/1213 (4%) Query: 20 LISYIERGSTVLKFFPRKR-PERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEV 78 ++ +ERG+ +++F RKR PE++ C++ +T +V+ + R E ++DIR++KEV Sbjct: 16 ILGALERGTVMVRFPARKRRPEKKLFCLKVDTFEVVQYPLTKGTRTVAEESIDIREIKEV 75 Query: 79 RTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA 138 R G SSKDFER P+ETK+++ CF IY+GTEF+L S A EC+AWVK + ++ Sbjct: 76 REGVSSKDFERQPDETKKVDQYCCFVIYHGTEFRLTTLSVAALCRDECDAWVKALKHVTL 135 Query: 139 EAVSASYPLQIERWLRKEFYSIENSHEKITLK--EVKAFLPKINCKISTSKLRDVFQDVD 196 AS+ L RWL KEF ++E S + +T+ E+K ++ +I+ K +K R +F D D Sbjct: 136 AGNFASH-LLTHRWLNKEFLALEPSGDNLTIGPIELKKYVLRISSKALLNKARQLFIDFD 194 Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256 + G +G +DF LY I +V+ I +++ +C++ ++T E Q F R+EQ D Sbjct: 195 YSRAGRMGVEDFFNLYHNTI----HVKTIGERFYPFCADRQSLTFSEVQMFFREEQKDKR 250 Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFT---LSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313 DD V + IR+Y R P R + +P L EFV L+SKQNS++ +Y ++ QDM R Sbjct: 251 ADDTVYLAGLIREYARVPNRTVRDPRLPSLLLPEFVNFLFSKQNSVFAEEYAQIYQDMDR 310 Query: 314 PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373 P+SHYWI+SSHNTYLTG+Q+SSESS E Y R LR GCRCIELDCWDGPDG P IYHG TL Sbjct: 311 PISHYWIASSHNTYLTGNQYSSESSCECYSRALRMGCRCIELDCWDGPDGNPIIYHGRTL 370 Query: 374 TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433 T+KIRF+DV++TIK+HAF+TSEYP+ILSIE +C + QQR MA F++VFGD LL +D Sbjct: 371 TSKIRFIDVIKTIKDHAFVTSEYPIILSIEQHCDIQQQRIMARQFKEVFGDALLTELVDL 430 Query: 434 NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKD-------LDLRNSIKNGILH 486 N T LPSP + +G EE+S + EE + DL NSI NG+L Sbjct: 431 NATRLPSP-NALKRKIIIKHKKLDGTEETSGNNKPEEAGEEEGVTFNSDLCNSILNGLLF 489 Query: 487 LEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWF 546 ++DP+DK W H FVLTE+KLY+T+ Q +P E H E WF Sbjct: 490 MQDPIDKNWAKHYFVLTEDKLYFTD----QQEKDEDEADKTETNTETLPSTEQHLKEKWF 545 Query: 547 HGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERG 606 HGKLAG R AE LL + + +G FLVRES TF GDY LSF R GK NHCRI K E G Sbjct: 546 HGKLAGGRVAAEKLLTDYKDV-NGAFLVRESTTFTGDYSLSFVRDGKYNHCRIHTKSEGG 604 Query: 607 VTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQ 666 T+FYLID FDS+Y LI HY+S+PL+S F L EPVPQ N H GK WFH + +R++ Sbjct: 605 KTRFYLIDQTLFDSIYELIMHYKSNPLKSPTFEQVLAEPVPQQNSHLGKAWFHENLSRSE 664 Query: 667 AEELLRKTNTDGAFLVRPSEKE----QGSFAISFRTEKEIKHCRVK-QEGRLYTIGTVKF 721 AEE+L+K DGAFL+RPSE+ Q ++AISFR E ++KHCR++ E Y IG+ F Sbjct: 665 AEEMLKKVRMDGAFLIRPSEQNTKAGQKNYAISFRAEGKVKHCRIEVDESGQYCIGSAIF 724 Query: 722 ESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTV 781 +SL ELV YYE +PLY++++L Y I+E+ ++ L D+ Y Y + +T Sbjct: 725 DSLTELVQYYEANPLYRRMRLKYAINEDLLKSLGEAESDDVYYHPIYYTFNEEKATPITC 784 Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPD 841 KAL+DY A + DELSFCK A+ITNV+K GWW+GD G K WFPAN+V E++ + Sbjct: 785 KALFDYTAVRPDELSFCKDAVITNVEKHGGGWWKGDCGNKNQKWFPANHVEEVQ---ADE 841 Query: 842 VTSGLENESAALGSLQKGVLDVLGAIVEL--VVGDGGGAARW--LVRVQSPAMYSPFDM- 896 VT E LG+LQ+G +D+ G E+ + + A + +++ +S + M Sbjct: 842 VT-----EDRQLGNLQQGAIDISGCTTEIHHLSSNNLYALKIVPMLKAESTELEKENHMG 896 Query: 897 ---AAATRESALEWXXXXXXXXXXXXXXXXX-------XXKMERTWRIAKEISDLIIYCR 946 AA + E L W K E+ RIA E+SD+I YCR Sbjct: 897 LMVAAQSLEEILRWQKAIDEARNKANSHALAQMEKEKERKKDEQKKRIAIEMSDIIAYCR 956 Query: 947 SVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQE--NTFFVKYHTTQLSRIYPKGQRID 1004 V F+ ++ G YN M SF ET+ E+++ + F V H T L+R+YPKGQR+D Sbjct: 957 PVPFDENKMNDMGKYYN-MCSFVETRVEKIVHNKSLAAQFLVHAH-TYLNRVYPKGQRLD 1014 Query: 1005 SSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK 1064 SSNY+PVP WN G QMV+LNYQT DK MQ+N GKF QNG CG++L MFE G+NP D Sbjct: 1015 SSNYDPVPMWNGGCQMVSLNYQTGDKSMQLNEGKFLQNGKCGYVLMSDCMFEPGFNPLDI 1074 Query: 1065 KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLN 1124 + K P+T+ +++IG RHL + GRG P VEVE+IG + D K T T +NG N Sbjct: 1075 ST--QKTSPITLSVQIIGGRHLLRQGRGMTCPLVEVEVIGVEVDYN-KYRTSTCKENGFN 1131 Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184 P+WN+ C+F++ NP LAL+RF V DED FG+ NF+GQA FP+LCLR GYRSVPL NAFSE Sbjct: 1132 PVWNEGCDFDINNPALALLRFTVLDEDAFGDANFLGQAVFPVLCLRTGYRSVPLRNAFSE 1191 Query: 1185 ELELSTLMVHLSI 1197 ELEL +L+VHL + Sbjct: 1192 ELELCSLLVHLEM 1204 >UniRef50_UPI0000660CE1 Cluster: Homolog of Brachydanio rerio "Phospholipase C gamma 1.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Phospholipase C gamma 1. - Takifugu rubripes Length = 1071 Score = 812 bits (2008), Expect = 0.0 Identities = 455/1023 (44%), Positives = 614/1023 (60%), Gaps = 71/1023 (6%) Query: 24 IERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTG 81 +E G+ + F+ +K RPERR ++ +T ++WSR P + EG +DI++++E+R G Sbjct: 6 LEMGTVMTVFYQKKSQRPERRTFQIKPDTRLLVWSR--NPDKS--EGEIDIQEIRELRLG 61 Query: 82 KSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAV 141 K S+DFER+PEE ++LE+++CF + YG EF+LR S +A +++E W+ G+ +++++ Sbjct: 62 KCSRDFERYPEEARKLEAAQCFIVLYGQEFRLRTLS-LAASEEEVNMWI-GLTWMMSDTQ 119 Query: 142 SASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSK-LRDVFQDVDTEKR 200 A P Q + +T+K+VKA LP+IN ++ + L+D Q+V E R Sbjct: 120 RAPAPQQT---------------DSVTVKDVKALLPQINYRVPNMRFLKDKLQEV--EAR 162 Query: 201 GEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDE 260 ++ F +FA LY+ L+FD + +V I+L +FQ FL+ +Q ++ D Sbjct: 163 SDLTFPNFAQLYRTLMFDAQKNVSGSELLNVDRPELCQISLYDFQKFLQMDQKESWASDL 222 Query: 261 VQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYW 319 F+ Y+R QR EP L EF+ L+SK+NSI D Q DM RPLS YW Sbjct: 223 SLVRDFLMGYMRGGQR--AEPMLQLDEFLTFLFSKENSICDPQRLTLAPDDMKRPLSQYW 280 Query: 320 ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRF 379 ISSSHNTYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGPD P IYHGHTLT+KI+F Sbjct: 281 ISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKF 340 Query: 380 MDVLRTIKEHAFITSE-YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSL 438 +DVL TIKEHAF+TSE YP+ILSIED+CS+ QQR MA+ F+ VFGDLLL P+D + L Sbjct: 341 LDVLHTIKEHAFVTSERYPVILSIEDHCSVVQQRNMATHFRKVFGDLLLSKPVDNSAEEL 400 Query: 439 PSPHDXXXXXXXXXXXXPEGA--EESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDKEWK 496 PSPH EG EE S A E DL NS+KNGIL+LEDP+D W Sbjct: 401 PSPHQLRRKILIKHKKLVEGTLYEEVSSASYSEN----DLSNSLKNGILYLEDPIDHTWT 456 Query: 497 PHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAG---N 553 PH FVLT NK+YY+E SQ +E H AE WFHGKL G Sbjct: 457 PHYFVLTSNKIYYSEE-TSQYQTADQEEEDEVKEEC--NNNEQHCAERWFHGKLGGGRDG 513 Query: 554 RQEAEDLLRAHAHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFY 611 RQ AE LL+ + G DGTFLVRES TFVGDY LSFWR G+V HCRI +QE G T+FY Sbjct: 514 RQVAEKLLQDYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFY 573 Query: 612 LIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELL 671 L D++ FDSLY L+ HYR PLR EF + L PVPQPN HE +EW+H+ +R QAE +L Sbjct: 574 LTDNLVFDSLYRLMCHYRDTPLRCNEFEMRLGSPVPQPNAHESREWYHSSLSRVQAEHML 633 Query: 672 RKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIG-TVKFESLIELVSY 730 + DGAFLVR E S+AISFR E +IKHCR++QEGRL+ +G + +FESL++LV+Y Sbjct: 634 MRVPRDGAFLVR-KRSESHSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLVDLVNY 692 Query: 731 YENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRAR 790 YE HPLY+K++L YPI+E+T+ R+ + G P F + + V Sbjct: 693 YEKHPLYRKMRLRYPINEDTLDRMGTTVSQARPPGVSA-TTPDHFHTFMRVSLF----LH 747 Query: 791 QDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENES 850 +D E+ C T D+ G R PA V + H + S E+ Sbjct: 748 EDSEVQICS----TMTDEHLGGCLR----------LPAATVPARFMTHCFLLLS-QSTEN 792 Query: 851 AALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSPAMYS----PFDMAAATRESALE 906 + LG+ KG +DV V +V +G + ++ V S S D++A + E Sbjct: 793 SPLGTFLKGFMDVSTCHV-VVHAEGKNSRPFVFTVHSQNFSSQPVQSLDVSADSLEELTH 851 Query: 907 WXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMS 966 W +MER +IA E+S+L++YCR V FN +++ Y +MS Sbjct: 852 WVTKIREAAQNADARMQEEKQMERRKKIAVELSELVVYCRPVPFNEDKIGTDRACYKDMS 911 Query: 967 SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026 SFPETKAE+ ++ F++Y+ QLSR+YP+GQR+DSSNY+P+P W CGSQ+VALN+Q Sbjct: 912 SFPETKAEKFTTRSRGKRFLQYNRRQLSRVYPRGQRLDSSNYDPLPMWLCGSQLVALNFQ 971 Query: 1027 TPD 1029 TP+ Sbjct: 972 TPE 974 Score = 103 bits (246), Expect = 4e-20 Identities = 46/88 (52%), Positives = 64/88 (72%), Gaps = 1/88 (1%) Query: 1112 KLVTKTVSDNGLNPLWNDI-CEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170 +L +DNGLNP+W F+V NP + +RF V DED+F +PNF+ QATFP+ L+ Sbjct: 981 ELCVLLAADNGLNPVWVQTHFVFDVHNPTFSFLRFTVYDEDMFSDPNFLAQATFPVQLLQ 1040 Query: 1171 KGYRSVPLTNAFSEELELSTLMVHLSII 1198 GYRSVPL N++SEELEL++L+VH+ I+ Sbjct: 1041 TGYRSVPLRNSYSEELELASLLVHVEIV 1068 >UniRef50_Q4SVT4 Cluster: Chromosome undetermined SCAF13726, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF13726, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1377 Score = 803 bits (1986), Expect = 0.0 Identities = 464/1027 (45%), Positives = 606/1027 (59%), Gaps = 115/1027 (11%) Query: 24 IERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTG 81 +E G+ + F+ +K RPERR VR + ++WSR P + EG LDI+D++E+R G Sbjct: 2 LETGTVMTLFYQKKSQRPERRTFQVRPDMRLLVWSR--NPDKP--EGELDIQDIRELRLG 57 Query: 82 KSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAV 141 K S+DFER+PEE ++L+++ CF + YG EF+LR S A +++E W+ G+ +L+ + Sbjct: 58 KGSRDFERYPEEARKLDAAHCFIVLYGQEFRLRTLSLAAFSEEEVNMWMTGLTWLMTDTQ 117 Query: 142 SASYPLQIERWLRKEFYSIENSHE------------------------KITLKEVKAFLP 177 A P Q +RWLRK+F ++ +HE +T+K+VKA LP Sbjct: 118 RAPAPQQTDRWLRKQFEVMDRNHEGRWVTLPEHVNIQSQQPVRDAPHSSVTVKDVKALLP 177 Query: 178 KINCKISTSK-LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNV---QDIFDKYS--V 231 +IN ++ + L+D Q+V E R ++ + +FA LY+ L+FD ++ ++ Sbjct: 178 QINFRVPNMRFLKDKLQEV--EARSDLTYPNFAQLYRTLMFDSQKTVSGSELLSSWNSPS 235 Query: 232 YCSNGT--------TITLREFQNFLR--------DEQHD-----NLGDDEVQASQF--IR 268 C T + T R F + R D + +L E AS +R Sbjct: 236 LCGTSTDRNSARFPSTTSRSFCRWTRRYGDGLPLDSRRALLTSVSLSSQEPWASDLGRVR 295 Query: 269 DYLRDPQR--DIYEPYFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHN 325 ++L R EP L EF+ L+SK+NSI D Q V DM RPLS YWISSSHN Sbjct: 296 EFLMGYLRGGQQAEPMLQLDEFLTFLFSKENSICDPQLLAVVPDDMKRPLSQYWISSSHN 355 Query: 326 TYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRT 385 TYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGPD P IYHGHTLT+KI+F+DVL T Sbjct: 356 TYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKFLDVLHT 415 Query: 386 IKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXX 445 IKEHAF+TSEYP+ILSIED+CS+ QQR MA+ F+ VFGDLLL P+D N LPSPH Sbjct: 416 IKEHAFVTSEYPVILSIEDHCSVVQQRNMATHFKKVFGDLLLTKPVDNNAEELPSPHQLR 475 Query: 446 XXXXXXXXXXPEGA--EESSFAVRQEEGKDLDLRNSIKNGILHLEDPVDKEWKPHAFVLT 503 EG EE S A E D+ NS+KNGIL LEDPVD W PH FVLT Sbjct: 476 RKILIKHKKLVEGTLYEEVSSASYSEN----DISNSLKNGILFLEDPVDHTWTPHYFVLT 531 Query: 504 ENKLYYT-ESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAG---NRQEAED 559 NK+YY+ E+ + Q N +E H AE WFHGKL G RQ AE Sbjct: 532 SNKIYYSEETSHYQTADEEEDDEVKEECN----NNEQHCAERWFHGKLGGGRDGRQVAEK 587 Query: 560 LLRAHAHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMC 617 LL+ + G DGTFLVRES TFVGDY LSFWR G+V HCRI +QE G T+FYL D++ Sbjct: 588 LLQEYCEGGAKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRFYLTDNLV 647 Query: 618 FDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTD 677 FDSLY LI HYR PLR EF + L PVPQPN HE +EW+H+ TR QAE +L + D Sbjct: 648 FDSLYRLICHYRDTPLRCNEFEMRLGNPVPQPNAHESREWYHSSLTRVQAEHMLMRVPRD 707 Query: 678 GAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIG-TVKFESLIELVSYYENHPL 736 GAFLVR E S+AISFR E +IKHCR++QEGRL+ +G + +FESL++LVSYYE HPL Sbjct: 708 GAFLVR-KRSEHNSYAISFRAEGKIKHCRIQQEGRLFMLGSSAEFESLMDLVSYYEKHPL 766 Query: 737 YKKVKLWYPISEETV--------------RRLV----------SEPDDNTVY--GTPG-Y 769 Y+K+KL YPI+E+T+ RR V E D +Y TP Y Sbjct: 767 YRKMKLRYPINEDTLDKMGTTVSRAPPERRRSVESQMMKPPVPQELDYGALYEVRTPHFY 826 Query: 770 MDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828 ++ T++ TVKALYDYRA+++DEL F K A+I NVDK + GWWRGDYGGK+ WFPA Sbjct: 827 VEANKMPTARCTVKALYDYRAQREDELCFSKQALILNVDKQEGGWWRGDYGGKKQLWFPA 886 Query: 829 NYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVLGAIVELVVGDGGGAARWLVRVQSP 888 NYV E+ ++ + ++++ LG+ KG LDV V +V DG + ++ V S Sbjct: 887 NYVEELPSSPLRELDEAVSSKNSPLGTFLKGFLDVTSCHV-VVHKDGKNSRPYVFTVHSQ 945 Query: 889 AMYS----PFDMAAATRESALEWXXXXXXXXXXXXXXXXXXXKMERTWRIAKEISDLIIY 944 S D++A + E + W +MER +IA E+SDL++Y Sbjct: 946 HFSSQPVQSLDVSADSLEELIHWVTKIREAAQNADARMQEEKQMERRKKIAVELSDLVVY 1005 Query: 945 CRSVTFN 951 CR V FN Sbjct: 1006 CRPVPFN 1012 Score = 130 bits (313), Expect = 3e-28 Identities = 73/166 (43%), Positives = 97/166 (58%), Gaps = 25/166 (15%) Query: 1029 DKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI------- 1081 DKPMQ+N F GG G+I +P M E+ ++P DK ++ V+P+T+ L+V+ Sbjct: 1160 DKPMQLNQAFFLLGGGSGYIPQPDVMREDVFDPFDKDTLN--VEPITIQLQVLPNSQGCN 1217 Query: 1082 --------------GARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW 1127 GARHL K GR PFVEVEI GADYDS K T V+DNGLNP+W Sbjct: 1218 QSESYPCPWPLQVLGARHLPKNGRSIVCPFVEVEICGADYDS-CKYKTDVVADNGLNPVW 1276 Query: 1128 -NDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172 F++ NP + +RF V DED+F +PNF+ QAT+P+ LR G Sbjct: 1277 LQKQFVFDIHNPTFSFLRFTVYDEDMFSDPNFLAQATYPVQLLRTG 1322 >UniRef50_Q22070 Cluster: Putative uncharacterized protein plc-3; n=2; Caenorhabditis|Rep: Putative uncharacterized protein plc-3 - Caenorhabditis elegans Length = 1299 Score = 700 bits (1730), Expect = 0.0 Identities = 395/1058 (37%), Positives = 585/1058 (55%), Gaps = 59/1058 (5%) Query: 167 ITLKEVKAFLP-KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI 225 + K +K F+ + K+ + +L+ V +D + F +++ +F + D+ Sbjct: 161 VARKHMKPFVQTSLQFKVQSDQLQQVTED--QMNSDQFSFASRQLIHVPELFS-SRFADL 217 Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQR---DIYEPY 282 +K+ G +T + F FL +Q D L + +A +F+ Y ++ Q D EP Sbjct: 218 AEKHE---RKGLVVTFQNFLRFLDGKQFDELASNRTRALEFLNRYFQEDQAYFGDRNEPS 274 Query: 283 FTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342 T+ EF + L+S++NS++D +KVT DM+RPLSHYWI+SSHNTYLTGDQ SESSL+ Y Sbjct: 275 MTVFEFCDFLFSRENSLWDPTNEKVTHDMSRPLSHYWIASSHNTYLTGDQLRSESSLDCY 334 Query: 343 VRCLRSGCRCIELDCWDG---PDGTPFI----YHGHTLTTKIRFMDVLRTIKEHAFITSE 395 + L GCRCIELDCWDG P FI YHG+T+T+KI DVL I+ +AF+TSE Sbjct: 335 AQALLMGCRCIELDCWDGQKKPGSAEFIDIVIYHGYTMTSKILLRDVLHVIRHYAFVTSE 394 Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXX 455 YP+ILSIEDNCS+P QR +A +D+ GD LL P ++ E LPSP Sbjct: 395 YPVILSIEDNCSVPAQRLLAQELKDILGDYLLTQPANREEKQLPSPAALKKKIIVKHKKL 454 Query: 456 PEGAEESSFAVRQEEGKDLDL--RNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYT--- 510 P +E+ + V+ +E +D ++ R +K GIL +++ EW H F+L ++L Y Sbjct: 455 PIESEDLAAVVKTDEFQDTEIISRECVKKGILMVKNNNSHEWTSHVFILFPDRLCYLIQT 514 Query: 511 ---ESYNSQXXXXXXXXXXXXXXNAI--VPQDELHFAECWFHGKLAGNRQEAEDLLRAHA 565 E+ N + V +E+H E WFHG+ R EA+ + H Sbjct: 515 ADPENPNDDTVSVSGDEEREEETPSGFGVKPEEMHVTEEWFHGRC--ERDEAKKRILEHK 572 Query: 566 HLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLI 625 G+G F++R+S F+GD+ LS GKV+H RI+ K K+Y +D+ D+LY L+ Sbjct: 573 EKGNGLFMIRDSNLFIGDFSLSILHDGKVHHVRIRSKIIDKEKKYYFMDNKVCDTLYELV 632 Query: 626 THYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPS 685 ++Y H L + F + L P PQP H + WF A + +AEELL DGAFL+R S Sbjct: 633 SYYTRHYLTTAHFKMVLTIPCPQPQPHLNQPWFSATADKEKAEELLSLVPEDGAFLIRTS 692 Query: 686 EKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYP 745 + + +S + + E H R+K++GR++ + FE+L ++V +Y N + + L +P Sbjct: 693 STDSSVYVLSLKVDGEFWHYRLKRDGRIFVVNQKVFENLNQIVEFYANREFVRGISLRFP 752 Query: 746 ISEETVRRLVSEPDDNTVYGTPG-YMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIIT 804 ++E+ + L +E + TPG YMD +V +AL YR DDELSF + IIT Sbjct: 753 VNEKDISHLTAELAEAR---TPGCYMDLKDLDKEVQARALRPYRGTADDELSFPANVIIT 809 Query: 805 NVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDVL 864 V + +EG WRG YG WFP+ +V EI P+ S E + +++ Sbjct: 810 -VLRKEEGLWRGRYGSLT-GWFPSAHVQEI----LPEKVSTSETSN-------YNTIELA 856 Query: 865 GAIVELV-VGDGGGAARWLVRVQSPAMYSPFDMAAATRESALEWXXXXXXXXXXXXXXXX 923 G ++E + D R Q + +AA++ E A W Sbjct: 857 GTLIERIHDADRPNVIRISQSNQHWMNKQYYLLAASSSEEADGWQNNLFELTRSVNTKMS 916 Query: 924 XXXKMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENT 983 E+ RIA E+S+L++YC++V F + I + EM SF E K ++L+ + Sbjct: 917 ILRTKEKEKRIAAELSNLVVYCQAVPF--DPAHIYNDAFYEMCSFVEGKLDKLVEKG--- 971 Query: 984 FFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNG 1043 + +++ +LSR+YP G RI S+NY+PVP WN G MVALNYQT DKPMQ+N GKF NG Sbjct: 972 -LLPFNSRKLSRVYPNGSRITSNNYSPVPMWNAGCHMVALNYQTGDKPMQLNQGKFLANG 1030 Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK--TGRGTASPFVEVE 1101 CG++LKP +M + ++P + + P+ + ++VIG RHL + +G SPFVE+E Sbjct: 1031 RCGYLLKPDYMLTDDFDPTNTEKF-ATAYPIRLNVQVIGGRHLSRKDKNKGICSPFVEIE 1089 Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN--FI 1159 IIG D+ V TKT++ NGLNP+WN FE+ PE+ALIRF V+D D G FI Sbjct: 1090 IIGMPCDTKV-FQTKTIASNGLNPIWNQTFTFEIQCPEVALIRFHVEDGDFVGPKTDPFI 1148 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 GQA FP+ +R G+RSVPL N +SEELELS+L+V + + Sbjct: 1149 GQAVFPVDSIRCGFRSVPLKNQYSEELELSSLLVDVQM 1186 >UniRef50_Q4SKC0 Cluster: Chromosome 13 SCAF14566, whole genome shotgun sequence; n=2; Euteleostei|Rep: Chromosome 13 SCAF14566, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1249 Score = 654 bits (1617), Expect = 0.0 Identities = 353/863 (40%), Positives = 516/863 (59%), Gaps = 57/863 (6%) Query: 24 IERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKS 83 +E G+ + F R++ ER + V ET QV W+R +G LD+ +++E+R G++ Sbjct: 13 LEMGAVMTVF--RQKAERLTVQVIMETRQVAWTRT----ADKTDGVLDLFEIREIRPGRN 66 Query: 84 SKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVSA 143 SKDFER+ + + + + CFTI+YG++F L S + E + W+ G+ L E + A Sbjct: 67 SKDFERFRDGKDKHDENACFTIFYGSQFVLNTLSLGVDSVTEAQKWLTGLELLWKETLEA 126 Query: 144 SYPLQIERWLRKEFYSIENSH-EKITLKEVKAFLPKINCKISTSK-LRDVFQDVDTEKRG 201 P+ IE WLRK+ YS+ + IT+KE+K LP +N K ++ L+D FQ+V + K+ Sbjct: 127 PTPVLIESWLRKQMYSVNQTKTNSITVKELKTLLPLLNYKAPGARALKDKFQEVGS-KKD 185 Query: 202 EIGFDDFAVLYQKLIFDENNV---QDIFDKYSV-YCS---------NGTTITLREFQNFL 248 + F+ F LY ++F++N Q I +++ C+ + + + L +FQ FL Sbjct: 186 RLDFEQFHKLYNHIMFEQNEASLKQTILNEFKKDSCAFILGNTDKPDASAVMLHDFQRFL 245 Query: 249 RDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVT 308 +Q + D Q + + ++ D +P FT+SEF+ L+S++NSI+D + +++ Sbjct: 246 VYDQKECWAADLNQVRELMTIFIDDTMSKTNDPVFTVSEFLGYLFSEENSIWDKKVSEIS 305 Query: 309 -QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFI 367 DM PLSHYWI+SSHNTYLTGDQ SESS EAYVR LR GCRC+ELDCW+GP G P I Sbjct: 306 CMDMNNPLSHYWINSSHNTYLTGDQLRSESSTEAYVRALRLGCRCVELDCWEGP-GEPII 364 Query: 368 YHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL 427 YHG T TTKI+F DV++ I +HAF+TSE+P+ILSIE++C + QQR+MA F+DVFGD LL Sbjct: 365 YHGWTRTTKIKFEDVVKAINDHAFVTSEFPVILSIEEHCPIEQQRQMARIFRDVFGDKLL 424 Query: 428 VHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEEGKDLDLRNSIKNGILHL 487 P+++ LPSP + +V + G DLR K G L + Sbjct: 425 SEPVEQVAEQLPSPTQLKGKII---------LKHKKLSV-EGGGTAKDLRKGQKQGDLQI 474 Query: 488 EDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFH 547 DPVDK+W H V++++ LYY E + Q +LH E WFH Sbjct: 475 WDPVDKQWNKHYCVISDDNLYYAEEEEQEEEDT---------------QKDLHCTEPWFH 519 Query: 548 GKLAGNRQEAEDLLRAH-AHLG--DGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 G + RQ AE L+ + A G DGTFLVR S V Y LSFWR G+V HCR+++ + Sbjct: 520 GHMKDGRQMAERLIYEYCAETGGQDGTFLVRPSDRVVLSYTLSFWRNGRVQHCRVRVGNQ 579 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTR 664 G ++L ++ F SL +LI HYR +PLR Q+F + L + VPQP+ H + WF++ +R Sbjct: 580 GGRPYYFLTANLHFPSLISLIQHYRENPLRCQDFELRLTDAVPQPSPHLNEGWFYSDLSR 639 Query: 665 TQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVK-FES 723 QAE+ L + DGAFL+R E E SFAI+F+ + ++KHCR+++EG Y +GT FES Sbjct: 640 GQAEDYLMRIPRDGAFLIRQREGEPDSFAITFKGDGKVKHCRIQKEGTRYLLGTTTYFES 699 Query: 724 LIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTS---KVT 780 L+ELVSY+ N PLY+K+KL YP++ E V R + ++Y Y++P S K Sbjct: 700 LVELVSYFRNRPLYRKIKLRYPVTPELVERFSMGKECASLYSMKMYVEPNEIESALPKNA 759 Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTP 840 V+ALY Y+A + DELSF K A+I NV K + WW+GDYGGK +FPAN+V E+ P Sbjct: 760 VRALYCYQATRPDELSFNKGALIYNVSKETDDWWKGDYGGKVQFFFPANHVEEVSRGGGP 819 Query: 841 DVTSGLENESAALGSLQKGVLDV 863 ++T + +++ LG L KGV+D+ Sbjct: 820 ELTQQVMDDN-PLGELCKGVVDI 841 Score = 244 bits (596), Expect = 2e-62 Identities = 134/314 (42%), Positives = 185/314 (58%), Gaps = 18/314 (5%) Query: 894 FDMAAATRESALEWXXXX---XXXXXXXXXXXXXXXKMERTWRIAKEISDLIIYCRSVTF 950 FD++A T E EW ++E+ +A E+SDL++YC+ + Sbjct: 894 FDLSAETLEELFEWYQAAWDITQRKISKEYNRQHEVEVEKKEEVAMEMSDLVVYCQPRSK 953 Query: 951 NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNP 1010 E+ R + Y E+ SF E K +E F+ Y+ LSRIYPKGQR++SSNY+P Sbjct: 954 --EKDRFDSYTYKEIRSFVENKVPGKNRTKE---FLLYNRKALSRIYPKGQRVESSNYDP 1008 Query: 1011 VPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGK 1070 P W G QMVALN+QT DK Q+N F NGG G++L+P+ M + ++P +K+ + Sbjct: 1009 YPLWAVGCQMVALNFQTADKYTQLNSALFSLNGGTGYVLQPEVMRSDVFDPLQEKN---R 1065 Query: 1071 VKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI 1130 V + +R+I ARHL K GR ASPFVEVE+ G + K T DNGLNP+W Sbjct: 1066 VM-YMMDVRIIAARHLPKPGRSIASPFVEVELCG---HTDEKFKTAVYRDNGLNPVWKAP 1121 Query: 1131 CE---FEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELE 1187 E F V ELA +RFVV +ED+F +PNF+ QATFP+ +R GYRSVP+ N +SE LE Sbjct: 1122 AEPMTFTVHEHELAFLRFVVYEEDMFSDPNFLAQATFPVQGIRSGYRSVPMRNGYSERLE 1181 Query: 1188 LSTLMVHLSIITDG 1201 L++L+VH+ I T G Sbjct: 1182 LASLLVHIDIKTAG 1195 >UniRef50_Q4T6N5 Cluster: Chromosome 9 SCAF8684, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 9 SCAF8684, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 966 Score = 357 bits (877), Expect = 1e-96 Identities = 181/335 (54%), Positives = 233/335 (69%), Gaps = 13/335 (3%) Query: 540 HFAECWFHGKL-AGN--RQEAEDLLRAHA-HLG--DGTFLVRESVTFVGDYCLSFWRQGK 593 H E WFHGKL AG RQ AE LL + G DG+FLVRES TFVGDY LSFWR G+ Sbjct: 624 HVTEKWFHGKLGAGRDGRQIAERLLSEYCMETGAPDGSFLVRESETFVGDYTLSFWRSGR 683 Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653 V HCRI +QE G KFYL D++ FD+L+ LI HY+ LR EF + L EPVPQ N HE Sbjct: 684 VQHCRIHSRQEAGSPKFYLTDNLVFDTLFALINHYQQVALRCNEFEMKLTEPVPQTNAHE 743 Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713 KEW+HA+ +R+QAE +L + DGAFLVR E SFAISFR E +IKHCRV+QEG+ Sbjct: 744 SKEWYHANLSRSQAENMLMRVPRDGAFLVR-KRAEPNSFAISFRAEGKIKHCRVQQEGQT 802 Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRL-VSEPDDNTVY--GTPG-Y 769 +GT +F+SL++L+SYYE HPLY+K+KL YPI+E+T+ ++ +EPD ++Y PG Y Sbjct: 803 VVLGTSEFDSLVDLISYYEKHPLYRKMKLRYPINEDTLEKIGTAEPDYGSLYEGRNPGFY 862 Query: 770 MDPTSF-TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828 ++ T K TV+A+Y+Y+A++DDELSF K+AII NVDK + GWW+GD GGK+ WFPA Sbjct: 863 VEANQMPTFKCTVRAMYEYKAQRDDELSFTKNAIIYNVDKQEGGWWKGDCGGKKQLWFPA 922 Query: 829 NYVLEIEVPHTPDVTSGLENESAALGSLQKGVLDV 863 NYV EI P + E++ LG L +G +DV Sbjct: 923 NYVEEIS-PSAAEPDRAEMTENSPLGDLLRGSVDV 956 Score = 272 bits (667), Expect = 4e-71 Identities = 122/185 (65%), Positives = 147/185 (79%), Gaps = 1/185 (0%) Query: 259 DEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQD-MTRPLSH 317 D +F+ YL+DP R++ +PYF EF+ ++SK+N+I+DS D+V + M PLSH Sbjct: 279 DTNTVQEFMFSYLKDPLREVEQPYFHQDEFLTYMFSKENTIWDSSRDQVCPEKMNDPLSH 338 Query: 318 YWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKI 377 YWISSSHNTYLTGDQFSSESSLEAY RCLR GCRCIELDCWDGP+G P IYHGHTLTTKI Sbjct: 339 YWISSSHNTYLTGDQFSSESSLEAYARCLRMGCRCIELDCWDGPEGMPVIYHGHTLTTKI 398 Query: 378 RFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS 437 +F DVL TIKEHAF+TS+YP+ILSIED+CS+ QQR MAS F+ VFGD+LL P+D Sbjct: 399 KFSDVLMTIKEHAFVTSDYPIILSIEDHCSIVQQRNMASHFKKVFGDMLLTKPVDIAADG 458 Query: 438 LPSPH 442 LPSP+ Sbjct: 459 LPSPN 463 Score = 146 bits (354), Expect = 3e-33 Identities = 70/172 (40%), Positives = 114/172 (66%), Gaps = 8/172 (4%) Query: 16 EADQLISYIERGSTVLKFFPRK--RPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73 E + L +E G+ + F+ +K RPERR V+ ET ++W+R EG +DIR Sbjct: 21 EMNNLYRDLELGTVLTLFYSKKSQRPERRTFQVKLETRTIIWTR----GTDKIEGEIDIR 76 Query: 74 DVKEVRTGKSSKDFERWPEETK-RLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKG 132 ++KE+R G+ S+DFER E++ RL+ + CF I YGTEF+L+ S A +D+E WVKG Sbjct: 77 EIKEIRPGQKSRDFERCLEDSAARLDQAHCFVILYGTEFRLKSLSLAATSDEEMTMWVKG 136 Query: 133 VLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKI 183 + +L+A+ + + PLQIERWLRK+FY+++ N ++I+ K++K+ L ++N ++ Sbjct: 137 LNWLVADTLKSPTPLQIERWLRKQFYAVDRNREDRISCKDLKSMLSQVNYRV 188 Score = 65.7 bits (153), Expect = 7e-09 Identities = 55/180 (30%), Positives = 84/180 (46%), Gaps = 14/180 (7%) Query: 458 GAEESSFAVRQEEGKDLDLRNSI-KNG-ILHLEDPVDKEWKPHAFVLTENKLYYT--ESY 513 GA + SF VR+ E D S ++G + H +E F LT+N ++ T Sbjct: 656 GAPDGSFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQEAGSPKFYLTDNLVFDTLFALI 715 Query: 514 NSQXXXXXXXXXXXXXXNAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFL 573 N VPQ H ++ W+H L +R +AE++L DG FL Sbjct: 716 NHYQQVALRCNEFEMKLTEPVPQTNAHESKEWYHANL--SRSQAENMLMRVPR--DGAFL 771 Query: 574 VRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 VR+ + +SF +GK+ HCR+ Q+ G T ++ + FDSL +LI++Y HPL Sbjct: 772 VRKRAE-PNSFAISFRAEGKIKHCRV---QQEGQT--VVLGTSEFDSLVDLISYYEKHPL 825 Score = 64.5 bits (150), Expect = 2e-08 Identities = 26/41 (63%), Positives = 34/41 (82%) Query: 475 DLRNSIKNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNS 515 D+ NSIKNGIL+LEDP++ EW PH FVLT +K+YY+E +S Sbjct: 523 DISNSIKNGILYLEDPINHEWYPHFFVLTSSKIYYSEETSS 563 >UniRef50_UPI0000E493A1 Cluster: PREDICTED: similar to phospholipase C-gamma; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to phospholipase C-gamma - Strongylocentrotus purpuratus Length = 409 Score = 266 bits (652), Expect = 2e-69 Identities = 124/239 (51%), Positives = 165/239 (69%), Gaps = 8/239 (3%) Query: 161 ENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDEN 220 +N + ++L+++K+FLP+IN K++T +LR+VF + D R EI FD LY L+F Sbjct: 3 KNKTDTVSLRDMKSFLPRINLKMNTKELREVFNEADRWGRQEIPFDGLLQLYNNLVFQ-- 60 Query: 221 NVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYE 280 Q++ D+ Y ++ +TL ++ FL EQ D + ++ + Q+IR Y D + E Sbjct: 61 --QEVADRLREYYNDMNRVTLNDYIRFLAQEQKDPVANNPHEVKQYIRKYFADSGKAAME 118 Query: 281 P----YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSE 336 FT+ EFV+ LYSK N I++ YD +T DM RPL YWI+SSHNTYLTGDQ SSE Sbjct: 119 SDSDLSFTVQEFVDYLYSKDNEIWNRFYDNITDDMERPLCDYWIASSHNTYLTGDQVSSE 178 Query: 337 SSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395 SS+EAY RCLR GCRC+ELDCWDGPDG P IYHGHTLTTKIRF DVL+TIKEHA+IT++ Sbjct: 179 SSVEAYARCLRMGCRCLELDCWDGPDGLPIIYHGHTLTTKIRFYDVLKTIKEHAWITTD 237 Score = 125 bits (301), Expect = 8e-27 Identities = 56/91 (61%), Positives = 69/91 (75%), Gaps = 4/91 (4%) Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837 KVTVKALYDY+A+++DELSFCKHAIITNVDK D GWW+GDYGGK++ WFP+NYV E+ P Sbjct: 321 KVTVKALYDYKAQREDELSFCKHAIITNVDKQDHGWWKGDYGGKKNMWFPSNYVEEVTTP 380 Query: 838 HTPDVTSGLENESAALGSLQKGVLDVLGAIV 868 D G + LG+LQKG +D+ G V Sbjct: 381 ANND--QG--QNATLLGNLQKGAVDITGCSV 407 >UniRef50_A7RPT6 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 877 Score = 258 bits (633), Expect = 5e-67 Identities = 148/439 (33%), Positives = 243/439 (55%), Gaps = 24/439 (5%) Query: 14 IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73 + D+ I+ + RGS ++K + R + E + W+ P ++G + + Sbjct: 10 VFTVDESIALMRRGSELIKLRSASKKYPRTYFLDSELANISWT----PSKKGDRAKIPVN 65 Query: 74 DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133 VKE+R G S F + E +CFT+ +G F VA +E W+ G+ Sbjct: 66 TVKEIREGTVSDAFSQCSEV---FPEERCFTLIHGESFAT--LDLVAANREEAMHWMIGL 120 Query: 134 LYLIAEAVSASYPLQIER----WLRKEFYSIENSHEKI-TLKEVKAFLPKINCKISTSKL 188 YL+A+ + P + ++ WLR + + + S + + ++ EV + K+N KIS ++ Sbjct: 121 RYLMAQHYGENEPTRRQKARDLWLRGIYTAADKSGDGLLSIDEVYFLMHKLNVKISNRQV 180 Query: 189 RDVFQDVDTE---KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245 R+ F+ DT+ G + F++FA Y+ + + ++++ Y ++ +T++E Sbjct: 181 RENFKAADTDTVNSSGLLDFEEFANFYKSI----STRRELYMLLLKYGNSKENMTVQELL 236 Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYD 305 NFLR EQ D+E S I+ Y + + F L S I++ ++ Sbjct: 237 NFLRIEQRVTECDEEY-CSNIIQTY-EPADSNKKNMLLGIDGFTSYLLSADGEIFNPEHS 294 Query: 306 KVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365 V QDMTRPLSHY+I+SSHNTYLTGDQ +S SS++ YVR L+SGCRC+ELDCWDG DG P Sbjct: 295 DVYQDMTRPLSHYFIASSHNTYLTGDQLASASSMDMYVRVLQSGCRCLELDCWDGKDGEP 354 Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425 +YHG+T+T+K++F V+ I + AF+ + YP+ILS+E++CS+ QQ+ MA+ +D F D+ Sbjct: 355 VVYHGYTMTSKVKFRYVILNINDFAFLNNRYPVILSLENHCSVEQQKFMANFMRDTFKDI 414 Query: 426 L-LVHPMDKNETSLPSPHD 443 L ++ M + LPSP + Sbjct: 415 LCILFFMLFDGKDLPSPQE 433 Score = 204 bits (498), Expect = 1e-50 Identities = 119/279 (42%), Positives = 166/279 (59%), Gaps = 18/279 (6%) Query: 929 ERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKY 988 +RT R+++ +SDL+ Y +S F + G + E+ S PE +A R + + T F +Y Sbjct: 598 KRTIRLSRHLSDLVAYTQSRAFKGLEVEEDGENHWEVISIPEPRAYRF-TDTKATQFTRY 656 Query: 989 HTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFI 1048 +L RIYP G RIDSSN NP FWNCG Q+VALNYQT + +Q+N GKF+ NG CG++ Sbjct: 657 TRYKLCRIYPAGYRIDSSNPNPQTFWNCGCQLVALNYQTEGRMLQINRGKFRANGNCGYV 716 Query: 1049 LKPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099 LKP + +E ++P +K I G K V + +RVI + L K RG P+VE Sbjct: 717 LKPDILCKESQSFDPMTRKDIPGVSKKV-LKIRVISGQQLPKPKDSILGDRGEIIDPYVE 775 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159 VEIIG D+ K TKTV DNG NP+W + F + P++AL+RFVV DED G +FI Sbjct: 776 VEIIGIPADTS-KYRTKTVIDNGFNPVWEETMVFLLNFPDIALVRFVVWDEDPIGR-DFI 833 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 GQ T P + G+R V L E L+ +T+ H++I+ Sbjct: 834 GQMTLPFQSIMPGFRHVHL-----EGLDQATVFCHVTIM 867 >UniRef50_Q3LUA8 Cluster: Phospholipase C-eta2; n=23; Euteleostomi|Rep: Phospholipase C-eta2 - Homo sapiens (Human) Length = 1416 Score = 248 bits (607), Expect = 7e-64 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P R+ + + I ++EV G+ S+ F+R+P+ + + + CF+IY+G+ + V+ Sbjct: 82 PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 137 Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175 + + WV G+ YL+A E A ++WL++ F + N +++ EV Sbjct: 138 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 197 Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234 L K+N + +++ +F++ DT+ +G +GF++F Y+ + + +D++ Y + Sbjct: 198 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 253 Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294 + + Q FL+ EQ + +++ Q I + + + + F S Sbjct: 254 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 311 Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354 I++ ++ V QDMT+PLSHY+I+SSHNTYL GDQ S+S ++ Y L++GCRC+E Sbjct: 312 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 371 Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414 +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M Sbjct: 372 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 431 Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441 A D+ GD L L ++ T+LPSP Sbjct: 432 AQYLTDILGDKLDLSSVSSEDATTLPSP 459 Score = 204 bits (498), Expect = 1e-50 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%) Query: 927 KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 + ++T ++++ +SDL+ Y +SV T +IE + ++SSF ETKA +++ QQ+ + Sbjct: 615 RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 670 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 ++++ QLSRIYP R+DSSNYNP PFWN G QMVALNYQ+ + +Q+N KF NGGC Sbjct: 671 LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 730 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098 G++LKP M + +NP + + G++K ++LR+I + L K RG PFV Sbjct: 731 GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 789 Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158 EVEIIG D + T+ V DNG NP W + F V PE+AL+RF+V D D G +F Sbjct: 790 EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 847 Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 IGQ T + GYR V + E +E +++ VH+++ Sbjct: 848 IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 881 >UniRef50_O75038 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2; n=27; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 - Homo sapiens (Human) Length = 1182 Score = 248 bits (607), Expect = 7e-64 Identities = 131/388 (33%), Positives = 224/388 (57%), Gaps = 17/388 (4%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P R+ + + I ++EV G+ S+ F+R+P+ + + + CF+IY+G+ + V+ Sbjct: 108 PSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGS--FDPNCCFSIYHGSHRE--SLDLVS 163 Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175 + + WV G+ YL+A E A ++WL++ F + N +++ EV Sbjct: 164 TSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQL 223 Query: 176 LPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234 L K+N + +++ +F++ DT+ +G +GF++F Y+ + + +D++ Y + Sbjct: 224 LHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM----STRRDLYLLMLTYSN 279 Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294 + + Q FL+ EQ + +++ Q I + + + + F S Sbjct: 280 HKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRS 337 Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354 I++ ++ V QDMT+PLSHY+I+SSHNTYL GDQ S+S ++ Y L++GCRC+E Sbjct: 338 PAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVE 397 Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414 +DCWDGPDG P ++HG+TLT+KI F DV+ TI ++AFI +EYP+ILSIE++CS+ QQ++M Sbjct: 398 VDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKM 457 Query: 415 ASAFQDVFGDLL-LVHPMDKNETSLPSP 441 A D+ GD L L ++ T+LPSP Sbjct: 458 AQYLTDILGDKLDLSSVSSEDATTLPSP 485 Score = 204 bits (498), Expect = 1e-50 Identities = 114/279 (40%), Positives = 170/279 (60%), Gaps = 20/279 (7%) Query: 927 KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 + ++T ++++ +SDL+ Y +SV T +IE + ++SSF ETKA +++ QQ+ + Sbjct: 641 RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 696 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 ++++ QLSRIYP R+DSSNYNP PFWN G QMVALNYQ+ + +Q+N KF NGGC Sbjct: 697 LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGGC 756 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098 G++LKP M + +NP + + G++K ++LR+I + L K RG PFV Sbjct: 757 GYVLKPGCMCQGVFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPRDSMLGDRGEIIDPFV 815 Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158 EVEIIG D + T+ V DNG NP W + F V PE+AL+RF+V D D G +F Sbjct: 816 EVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DF 873 Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 IGQ T + GYR V + E +E +++ VH+++ Sbjct: 874 IGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 907 >UniRef50_Q4KWH8 Cluster: Phospholipase C eta 1; n=45; Tetrapoda|Rep: Phospholipase C eta 1 - Homo sapiens (Human) Length = 1693 Score = 244 bits (597), Expect = 1e-62 Identities = 132/389 (33%), Positives = 217/389 (55%), Gaps = 19/389 (4%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P R+ + + I + +V G+ S+ F R E + S CFTIY+G + + Sbjct: 55 PSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGN--FDPSCCFTIYHGNH--MESLDLIT 110 Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175 +E W+ G+ YL+A E A ++W+++ F + N + ++E+ Sbjct: 111 SNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQL 170 Query: 176 LPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234 + K+N + K+R +FQ+ DT E +G + F++F V Y+ + +D++ Y Sbjct: 171 MHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLR----RDLYLLLLSYSD 226 Query: 235 NGTTITLREFQNFLRDEQH-DNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293 +T+ E FL+ EQ +N+ D I+ + + + + + F + Sbjct: 227 KKDHLTVEELAQFLKVEQKMNNVTTD--YCLDIIKKFEVSEENKV-KNVLGIEGFTNFMR 283 Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353 S I++ + +V QDM +PL +Y+I+SSHNTYLTGDQ S+S ++ Y R L+ GCRC+ Sbjct: 284 SPACDIFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCV 343 Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413 E+DCWDGPDG P ++HG+TLT+KI F DV+ TI +HAF+ +E+P+ILSIE++CS+ QQR+ Sbjct: 344 EVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRK 403 Query: 414 MASAFQDVFGDLLLVHPMDKNE-TSLPSP 441 +A + +FGD L + +D E LPSP Sbjct: 404 IAQYLKGIFGDKLDLSSVDTGECKQLPSP 432 Score = 196 bits (479), Expect = 2e-48 Identities = 113/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + +T ++ +E+SDL++Y SV + + G N +S F ET+A +++ Q+ F + Sbjct: 590 RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 646 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 Y+ QL+RIYP RIDSSN+NP+P+WN G Q+VALNYQ+ + MQ+N KFK NG CG Sbjct: 647 -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKANGNCG 705 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099 ++LKPQ M + +NP + K ++L+VI + L K RG PFVE Sbjct: 706 YVLKPQQMCKGTFNPFSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 764 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159 VEIIG D K T+ V DNG NP+W + F V PE+AL+RF+V D D G +F+ Sbjct: 765 VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGR-DFV 822 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 GQ T L GYR V + E L +++ VH++I Sbjct: 823 GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 855 >UniRef50_UPI000069FB22 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4); n=2; Xenopus tropicalis|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4) - Xenopus tropicalis Length = 697 Score = 242 bits (592), Expect = 5e-62 Identities = 125/373 (33%), Positives = 216/373 (57%), Gaps = 13/373 (3%) Query: 72 IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVK 131 I ++EV GK S+ F+R+ + + + + CF+IYYG + V+ + +E W+ Sbjct: 2 IDSIQEVCEGKQSEIFQRYADGS--FDPNCCFSIYYGDH--MESLDLVSSSGEEARTWIT 57 Query: 132 GVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRD 190 G+ YL+A SY + WL++ F + N +++ EV + K+N + K++ Sbjct: 58 GLKYLMAGISDESYTCSYQIWLKQTFDEADKNGDGCLSINEVLQLMHKLNVNLPRQKVKQ 117 Query: 191 VFQDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249 +F++ DT+ +G +GFD+F Y+ + + +D++ Y ++ + + + FL Sbjct: 118 MFKEADTDDNQGTLGFDEFCAFYKMM----STRRDLYLLMLTYSNHKDHLDPDDLKRFLE 173 Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ 309 EQ + + + + P+ + + F + S I++ + +V Q Sbjct: 174 VEQK-MINVTKEYCLDIVDKFEPCPENK-KQGALGIDGFTNYMRSPAGDIFNPDHYQVNQ 231 Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH 369 DMT PLS+Y+I+SSHNTYL GDQ S+S ++ Y L++GCRC+E+DCWDGPDG P ++H Sbjct: 232 DMTLPLSNYFIASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHH 291 Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LV 428 G+TLT+KI F DV+ TI ++AFI ++YP+ILSIE++CS+ QQ++MA ++ G+ L L Sbjct: 292 GYTLTSKILFKDVIETINKYAFIRNDYPVILSIENHCSVVQQKKMAQYLIEILGEKLNLS 351 Query: 429 HPMDKNETSLPSP 441 ++++ T LPSP Sbjct: 352 DVVNEDSTKLPSP 364 Score = 185 bits (451), Expect = 6e-45 Identities = 105/269 (39%), Positives = 156/269 (57%), Gaps = 18/269 (6%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + ++T ++++ +SDL+ Y +SV + ++SSF ETKA +++ QQ+ FV Sbjct: 411 RQKKTMKLSRALSDLVKYTKSVGIHDVETESNW----QVSSFSETKAHQIL-QQKPAQFV 465 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ QLSRIYP R+DSSNYNP PFWN G Q VALNYQ+ + +Q+N KF NG CG Sbjct: 466 RFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQSVALNYQSEGRMLQLNRAKFNSNGNCG 525 Query: 1047 FILKPQFMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASP 1096 ++LKP+ M + +NP + + G++K ++LR+I + L K RG P Sbjct: 526 YVLKPKCMCQVIVGAFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPKDSMLGDRGEIIDP 584 Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156 FVEVE+IG D K T+ V DNG NP+W + F V PE++LIRF+V D D G Sbjct: 585 FVEVELIGLPVDC-FKEQTRVVDDNGFNPMWEETLVFTVHMPEISLIRFLVWDHDPIGR- 642 Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185 +FIGQ T + G + + F ++ Sbjct: 643 DFIGQRTLSFSSMMPGKKRAHVNVQFHKQ 671 >UniRef50_UPI0000F1F4FE Cluster: PREDICTED: similar to phospholipase C-like 3; n=3; Danio rerio|Rep: PREDICTED: similar to phospholipase C-like 3 - Danio rerio Length = 1715 Score = 238 bits (583), Expect = 6e-61 Identities = 138/437 (31%), Positives = 226/437 (51%), Gaps = 24/437 (5%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P R+ + + I + +V G+ S F R E + + S CFTIY+G + V Sbjct: 37 PSRKSEKAKITIDSLYKVTEGRQSDIFHRHAEGS--FDPSCCFTIYHGNH--MESLDLVT 92 Query: 121 QTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAF 175 +E WV G+ YL+A E A ++W+++ F + N + ++E+ Sbjct: 93 SNSEEARTWVTGLRYLMAGISDEDSLAKRQRTHDQWMKQTFEEADKNGDGLLNMEEIYQL 152 Query: 176 LPKINCKISTSKLRDVFQDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234 L K+N + K++ +FQ+ DT+ ++G + F++F V Y+ + +D+F + Sbjct: 153 LHKMNVNLPRRKVKQMFQEADTDDQQGTLTFEEFTVFYKMMSLR----RDLFLLLMCFSD 208 Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYS 294 +T E NFLR EQ + + I + + + + F + S Sbjct: 209 KKDHLTAEELGNFLRVEQ--KMSSVTPECCLDIINKFEVSEENKQNGVLGIEGFTNYMRS 266 Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354 +++ Q+ ++ QDM +P+ +Y+I+SSHNTYLTGDQ S S + Y L++GCRC+E Sbjct: 267 PACDVFNPQHHEINQDMDQPICNYFIASSHNTYLTGDQLLSHSKTDMYAWVLQAGCRCVE 326 Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414 +DCWDGPDG P + HG+TLT+KI F V+ TI ++AF+ +E+P+ILSIE++CS+ QQ+++ Sbjct: 327 VDCWDGPDGEPMVQHGYTLTSKITFKSVIETINKYAFVNNEFPVILSIENHCSIQQQKKI 386 Query: 415 ASAFQDVFGDLLLV-HPMDKNETSLPSPHDXXXXXXXXXXXXP-------EGAEESSFAV 466 A +++FGD L V ++K+ LPSP+ P E E S Sbjct: 387 AQHLKEIFGDKLDVGEALNKDPKQLPSPNLLKGKILLKGKRLPSYLSADAEEGEVSDDDS 446 Query: 467 RQEEGKDLDLRNSIKNG 483 E D L+NS NG Sbjct: 447 ADEIEDDFKLKNSTSNG 463 Score = 180 bits (439), Expect = 2e-43 Identities = 103/278 (37%), Positives = 157/278 (56%), Gaps = 19/278 (6%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + +T ++++++SDL+++ SV + +G N +S F E +A+ L+ + F Sbjct: 567 RRRKTIKLSRDLSDLVVFTNSVAS--QECLDEGSPCNVLS-FSEARAQNLVHHRAERFLT 623 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 ++ QLSRIYP RIDSSN+NP +WN G Q+VALNYQT + MQ+N KF NGG G Sbjct: 624 -FNQRQLSRIYPSAYRIDSSNFNPQTYWNVGCQLVALNYQTEGRMMQLNRAKFMVNGGSG 682 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099 ++LKP M + +NP + + K +++++I + L K RG PFVE Sbjct: 683 YVLKPSLMSKGAFNPLSDEPLPANPKK-QLVIKIISGQQLPKPPDSMLGDRGEIIDPFVE 741 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159 VEIIG D K T+ V DNG NP+W + F + PE+AL+RF+V D D G +F+ Sbjct: 742 VEIIGLPVDC-CKEQTRVVDDNGFNPVWEETLSFTLHMPEVALVRFLVWDHDPIGR-DFV 799 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 GQ T L GYR V + E + +++ VH+++ Sbjct: 800 GQRTIAFSSLMPGYRHV-----YLEGMTEASIFVHITV 832 >UniRef50_Q9BRC7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 4; n=24; Tetrapoda|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 4 - Homo sapiens (Human) Length = 762 Score = 237 bits (579), Expect = 2e-60 Identities = 133/378 (35%), Positives = 213/378 (56%), Gaps = 15/378 (3%) Query: 69 ALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECE 127 + I DV+ +R G S+ EE L + FTI ++G L +A + +E + Sbjct: 60 SFSISDVETIRNGHDSELLRSLAEE---LPLEQGFTIVFHGRRSNL---DLMANSVEEAQ 113 Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFY-SIENSHEKITLKEVKAFLPKINCKISTS 186 W++G+ L+ S + ++++WL F +N K++ +EV+ L +N ++ Sbjct: 114 IWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQRLLHLMNVEMDQE 173 Query: 187 KLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQN 246 +FQ DT + G + ++F Y K + VQ++F+ +S ++G +TL EF + Sbjct: 174 YAFSLFQAADTSQSGTLEGEEFVQFY-KALTKRAEVQELFESFS---ADGQKLTLLEFLD 229 Query: 247 FLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDK 306 FL++EQ + E+ A + I Y + ++ F+ L SK I++ Sbjct: 230 FLQEEQKERDCTSEL-ALELIDRYEPSDSGKLRH-VLSMDGFLSYLCSKDGDIFNPACLP 287 Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366 + QDMT+PL+HY+I SSHNTYL GDQ +SS+E Y+R L+ GCRC+E+D WDGP G P Sbjct: 288 IYQDMTQPLNHYFICSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDVWDGPSGEPV 347 Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426 +YHGHTLT++I F DV+ T+ ++AF TS+YP+ILS+E +CS QQ+ MA ++ G+ L Sbjct: 348 VYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETHCSWEQQQTMARHLTEILGEQL 407 Query: 427 LVHPMD-KNETSLPSPHD 443 L +D T LPSP + Sbjct: 408 LSTTLDGVLPTQLPSPEE 425 Score = 195 bits (476), Expect = 5e-48 Identities = 109/266 (40%), Positives = 158/266 (59%), Gaps = 11/266 (4%) Query: 938 ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997 +S L+IY +SV+F + + + E+SSF ETKA+RL+ + N F V+++T QLSR+Y Sbjct: 493 LSSLVIYLKSVSFRSFTHSKEHYHFYEISSFSETKAKRLIKEAGNEF-VQHNTWQLSRVY 551 Query: 998 PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055 P G R DSSNYNP WN G QMVA+N QT M + G F+QNGGCG++LKP F+ Sbjct: 552 PSGLRTDSSNYNPQELWNAGCQMVAMNMQTAGLEMDICDGHFRQNGGCGYVLKPDFLRDI 611 Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGT-ASPFVEVEIIGADYDSGV 1111 + ++P +K I K T++++VI + L KT G+ P V+V+I G D+ Sbjct: 612 QSSFHP--EKPI-SPFKAQTLLIQVISGQQLPKVDKTKEGSIVDPLVKVQIFGVRLDT-A 667 Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171 + T V +NG NP W F V PELA++RFVV D D +FIGQ T P C+++ Sbjct: 668 RQETNYVENNGFNPYWGQTLCFRVLVPELAMLRFVVMDYDWKSRNDFIGQYTLPWTCMQQ 727 Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197 GYR + L + L +++ V++ I Sbjct: 728 GYRHIHLLSKDGISLRPASIFVYICI 753 >UniRef50_Q8K3R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 4; n=11; Theria|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 4 - Mus musculus (Mouse) Length = 807 Score = 236 bits (578), Expect = 2e-60 Identities = 138/414 (33%), Positives = 227/414 (54%), Gaps = 22/414 (5%) Query: 72 IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECEAWV 130 I DV+ +R G+ S + R+ E LE FT+ ++G L VA + +E + W+ Sbjct: 63 ISDVERIRKGQDS-ELLRYLVEEFPLEQG--FTVVFHGRRPNL---DLVANSVEEAQIWM 116 Query: 131 KGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLR 189 +G+ L+ S + Q+++ L + F + + + +++ +E + L +N ++ Sbjct: 117 RGLQLLVDLVASMDHQEQMDQMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAF 176 Query: 190 DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249 +FQ+ D + ++G ++F Y K + +++IF+ +S S+ +TL EF +FLR Sbjct: 177 SLFQEADVTQSDDLGSEEFVQFY-KALTKRTEIEEIFEDFS---SDKQKLTLLEFVDFLR 232 Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ 309 EQ + D + + D + + F++ L SK +I++S + Q Sbjct: 233 KEQKEK--DHAPDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQ 290 Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH 369 DMT+PLSHY+I+SSHNTYL GDQ +SS+E Y+R L+ GCRC+E+D WDGPDG P +YH Sbjct: 291 DMTQPLSHYYINSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYH 350 Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVH 429 GHTLT++I F DVL T+ ++AF +S+YPLILS+E++C+ QQR MA ++ G+ LL + Sbjct: 351 GHTLTSRILFKDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRN 410 Query: 430 PMD-KNETSLPSPHD-------XXXXXXXXXXXXPEGAEESSFAVRQEEGKDLD 475 ++ S+PSP E EE + ++EG DLD Sbjct: 411 TLEGLLVDSMPSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLD 464 Score = 175 bits (425), Expect = 8e-42 Identities = 99/279 (35%), Positives = 155/279 (55%), Gaps = 11/279 (3%) Query: 928 MERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVK 987 + T + ++S L++Y R+V F + + ++SSF E+KA+ L+ + N F V+ Sbjct: 528 LSSTTIMCPDLSALVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEF-VQ 586 Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047 ++ QL R+YP G R DSSN+NP WN G QMVA+N QT M + G F+QNGG G+ Sbjct: 587 HNARQLCRVYPSGLRTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGY 646 Query: 1048 ILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVE 1101 +LKP+F+ + +NP S+ K ++++VI + L K + P V+VE Sbjct: 647 VLKPEFLRDTQSSFNPERPISL---YKAQILVVQVISGQQLPKVDKTKETTVVDPLVKVE 703 Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQ 1161 + G D+ + T V +NG+NP W + F + PELA++RFVV+D NFIGQ Sbjct: 704 LYGVPEDT-KEQETSHVENNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQ 762 Query: 1162 ATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSIITD 1200 T P C+++GYR V L + L +++ V+ + D Sbjct: 763 YTLPWTCMKQGYRHVSLLSRDGTSLNPASIFVYTCMQED 801 >UniRef50_UPI0000F1EF3B Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 750 Score = 234 bits (573), Expect = 9e-60 Identities = 133/374 (35%), Positives = 210/374 (56%), Gaps = 17/374 (4%) Query: 72 IRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYY-GTEFKLRCASFVAQTDKECEAWV 130 I DV+ VR G S+ +E +CFT+ + G + L VA++ +E +AW+ Sbjct: 63 ISDVEAVREGHQSEALLGVADE---FPPDRCFTLVFRGRKGNL---DLVAESAEEAQAWI 116 Query: 131 KGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLR 189 +GV L+ + ++++W+ F + N +I KE K L +N ++ Sbjct: 117 QGVRGLMENMENMDESTKLDQWISDWFSKADRNKDGRINFKEAKKLLKMMNIDMNEEHAC 176 Query: 190 DVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLR 249 +F+ D + G + +F Y K++ + V D+F YS S+G ++ + + FLR Sbjct: 177 CLFKMADKSRSGTLEDQEFVEFY-KMLTERREVLDLFQDYS---SDGQILSQCDLEEFLR 232 Query: 250 DEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPY-FTLSEFVEMLYSKQNSIYDSQYDKVT 308 +EQ + E A Q I Y +P + ++ F+ L S + SI++ + + Sbjct: 233 EEQLEGESSYE-HALQLIDRY--EPSETARMNHSMSVDGFLMYLTSPEGSIFNPERQGIF 289 Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 QDM++ L+HY+ISSSHNTYL DQ SS+EAY++ L+ GCRC+E+DCW+G +G P +Y Sbjct: 290 QDMSQSLAHYYISSSHNTYLMEDQLKGPSSVEAYIQALKRGCRCVEVDCWNGANGEPVVY 349 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 HGHT T+KI DV+ TI +AF SEYPLI+SIE++CS+ QQ+ MA F+++ GD+LL Sbjct: 350 HGHTFTSKILLKDVITTIASYAFKASEYPLIISIENHCSVEQQKVMAQQFREILGDMLLT 409 Query: 429 HPMDKNETS-LPSP 441 D +S LPSP Sbjct: 410 STADTEVSSELPSP 423 Score = 202 bits (494), Expect = 3e-50 Identities = 116/270 (42%), Positives = 159/270 (58%), Gaps = 11/270 (4%) Query: 934 IAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 + KE+SD I++C+SV F+ E RI Y EMSSF E+KA R S++ + FV ++T Q Sbjct: 475 LCKELSD-IMFCKSVHFHSFEHSRISAKPY-EMSSFSESKA-RKYSKEAGSDFVLHNTRQ 531 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 L R+YP G R DSSNY PV W+ G Q+VALN+QT M +N G F QNG G++LKP+ Sbjct: 532 LIRVYPSGMRTDSSNYCPVDMWSMGCQIVALNFQTAGMEMDLNDGLFSQNGCSGYVLKPE 591 Query: 1053 FM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGADY 1107 + E ++P +K P+ ++VI + L K + S PFV VEI G Sbjct: 592 ILRNRERRFDP-EKPEEHEDYNPLVFSVKVISGQQLPKLKQNEWSIVDPFVRVEIYGVPL 650 Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167 D K TK + +NG NP WN+ +F V PELAL+RFVV+D D +FIGQ T PL Sbjct: 651 DQ-AKQETKYIDNNGFNPYWNESVQFTVHTPELALVRFVVEDHDKASRNDFIGQYTLPLS 709 Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 C++ GYR V L + + S++ VH+ I Sbjct: 710 CIQPGYRHVHLLSKDGTSIRPSSIFVHIKI 739 >UniRef50_A5D6R3 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; n=14; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 784 Score = 232 bits (568), Expect = 4e-59 Identities = 140/430 (32%), Positives = 223/430 (51%), Gaps = 19/430 (4%) Query: 18 DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77 D+ + + +GS ++K ++ + R L + + V ++ + + +V+ Sbjct: 34 DEDVLLMLQGSKMMKVRSQRWRKDRRLKLLEDCVTVWCESSKTSRKSNRQQTFSVTEVEC 93 Query: 78 VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137 VR G S+ R T + CFT+ + K T +E E WV+G+ L Sbjct: 94 VREGCQSECLRRM---TDLVPEKNCFTVVFRGGRK--SLDLCCHTQEEAERWVRGIRTLK 148 Query: 138 AEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDVD 196 + S +++ W+R + + + K++ EVK L IN ++ R +F+ D Sbjct: 149 DRVSNMSQKEKLDHWIRGYLRRADQNQDGKMSYDEVKHLLQLINIDLNEQYARTLFKKCD 208 Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256 G + + ++++ + +F YS NG +T E ++FL D+ D Sbjct: 209 RSCDGRLDHVEIEEFCREMM-RRPELDAVFRHYS---GNGCVLTTLELRDFLGDQGEDA- 263 Query: 257 GDDEVQASQFIRDY-LRD-PQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRP 314 V A I+ + L D Q++++ T + F + SK+N +++ + V QDM++P Sbjct: 264 --SLVHAKSLIQTFELNDWAQKNLF---MTQNGFTMYMLSKENDVFNPDHTHVYQDMSKP 318 Query: 315 LSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLT 374 L+HY+ISSSHNTYLT DQ +S SS E Y+R L GCRC+ELDCWDG G P IYHGHTLT Sbjct: 319 LAHYYISSSHNTYLTKDQVTSASSTEPYIRALNQGCRCVELDCWDGDKGEPIIYHGHTLT 378 Query: 375 TKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPM-DK 433 +K+ F +V+ TI ++AF S YPLILS+E++CS+ QQ MA Q + G LL P+ D Sbjct: 379 SKVLFKEVIETIAQYAFKASPYPLILSLENHCSVEQQAIMAQQLQSILGKKLLAKPLSDL 438 Query: 434 NETSLPSPHD 443 LPSP + Sbjct: 439 PLKQLPSPEE 448 Score = 194 bits (474), Expect = 9e-48 Identities = 106/276 (38%), Positives = 161/276 (58%), Gaps = 12/276 (4%) Query: 933 RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 +++ E+SDL++YC+SV F+ E + + ++SF E +A +L+ + FV+ ++ Sbjct: 501 KLSPELSDLVVYCQSVPFSGFETANQRP--PSVITSFSENEALKLI-KDSGKLFVRNNSR 557 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 QLSRIYP QR+ SSN++P WN G QMVALN+QTP + M +N G+F NG CG++LKP Sbjct: 558 QLSRIYPSAQRLQSSNFDPQDMWNAGCQMVALNFQTPGEQMDLNQGRFLPNGRCGYVLKP 617 Query: 1052 QFMFE--EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG----RGTASPFVEVEIIGA 1105 +F+ + ++P + G + P + +RVI A+ L K P V VEI G Sbjct: 618 EFLCDPKSDFDPENTGGGPGHI-PTQLTIRVISAQQLPKINTDKPNSIVDPQVWVEIHGV 676 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 D + T+ + +NG NP W+ F++ PELAL+RF+V+D D + +FIGQ T P Sbjct: 677 SIDK-ARAKTQRIDNNGFNPRWDCTVSFQLQLPELALVRFMVEDHDHKSKNDFIGQFTLP 735 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIITDG 1201 LR GYR V L A L +TL +H+ ++ G Sbjct: 736 FTSLRTGYRHVHLLKADGSTLSPATLFIHVKVVRRG 771 >UniRef50_Q8N3E9 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; n=22; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 - Homo sapiens (Human) Length = 789 Score = 231 bits (565), Expect = 9e-59 Identities = 143/460 (31%), Positives = 230/460 (50%), Gaps = 18/460 (3%) Query: 18 DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77 D+ + + RGS + K R + R ++ + V W + P R + ++ ++ Sbjct: 59 DEDVRAMLRGSRLRKIRSRTWHKERLYRLQEDGLSV-WFQRRIP-RAPSQHIFFVQHIEA 116 Query: 78 VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137 VR G S+ R+ ++C TI + + + + A T +E + WV+G+ L Sbjct: 117 VREGHQSEGLRRFGGA---FAPARCLTIAF--KGRRKNLDLAAPTAEEAQRWVRGLTKLR 171 Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196 A + S +++ W+ + + N K++ KE+K+ L +N ++ +F++ D Sbjct: 172 ARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFKECD 231 Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256 + + ++L+ +++IF +YS ++ E FL D+ + Sbjct: 232 HSNNDRLEGAEIEEFLRRLL-KRPELEEIFHQYS---GEDRVLSAPELLEFLEDQGEE-- 285 Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316 G +A Q I+ Y + +E TL F+ L S + + D+ + V QDM +PL+ Sbjct: 286 GATLARAQQLIQTYELNETAKQHE-LMTLDGFMMYLLSPEGAALDNTHTCVFQDMNQPLA 344 Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376 HY+ISSSHNTYLT Q SS EAYVR GCRC+ELDCW+GP G P IYHGHTLT+K Sbjct: 345 HYFISSSHNTYLTDSQIGGPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSK 404 Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK-NE 435 I F DV++ +++HAF S YP+ILS+E++C L QQ MA + GD+L+ +D N Sbjct: 405 ILFRDVVQAVRDHAFTLSPYPVILSLENHCGLEQQAAMARHLCTILGDMLVTQALDSPNP 464 Query: 436 TSLPSPHDXXXXXXXXXXXXPEGAEESSFAV--RQEEGKD 473 LPSP P E A+ R+EE +D Sbjct: 465 EELPSPEQLKGRVLVKGKKLPAARSEDGRALSDREEEEED 504 Score = 168 bits (408), Expect = 9e-40 Identities = 96/270 (35%), Positives = 147/270 (54%), Gaps = 11/270 (4%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I+ E+S L +YC + ++SS E KA++L+ + N+F V+++ Q Sbjct: 523 QISPELSALAVYCHATRLRTLHPAPNAPQPCQVSSLSERKAKKLIREAGNSF-VRHNARQ 581 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 L+R+YP G R++S+NY+P WN G Q+VALN+QTP M +N G+F NG CG++LKP Sbjct: 582 LTRVYPLGLRMNSANYSPQEMWNSGCQLVALNFQTPGYEMDLNAGRFLVNGQCGYVLKPA 641 Query: 1053 FMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG----RGTASPFVEVEIIGADY 1107 + + P E P T+ ++V+ A+ L K P V +EI G Sbjct: 642 CLRQ----PDSTFDPEYPGPPRTTLSIQVLTAQQLPKLNAEKPHSIVDPLVRIEIHGVPA 697 Query: 1108 DSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167 D + T V +NG NP W +F++ PELAL+RFVV+D D +F+GQ T PL Sbjct: 698 DC-ARQETDYVLNNGFNPRWGQTLQFQLRAPELALVRFVVEDYDATSPNDFVGQFTLPLS 756 Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L++GYR + L + L +TL + + I Sbjct: 757 SLKQGYRHIHLLSKDGASLSPATLFIQIRI 786 >UniRef50_P51178 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1; n=43; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 - Homo sapiens (Human) Length = 756 Score = 231 bits (564), Expect = 1e-58 Identities = 132/425 (31%), Positives = 216/425 (50%), Gaps = 13/425 (3%) Query: 18 DQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKE 77 D+ + + +GS +LK R +E + +W R I D++E Sbjct: 16 DEDLQALLKGSQLLKV-KSSSWRRERFYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQE 74 Query: 78 VRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLI 137 VR G ++ E++ + + +CF+I + + +A + + + WV G+ +I Sbjct: 75 VRMGHRTEGLEKFARD---VPEDRCFSIVFKDQ--RNTLDLIAPSPADAQHWVLGLHKII 129 Query: 138 AEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD 196 + S +++ W+ + N K++ KE++ FL ++N ++ S R +F++ D Sbjct: 130 HHSGSMDQRQKLQHWIHSCLRKADKNKDNKMSFKELQNFLKELNIQVDDSYARKIFRECD 189 Query: 197 TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNL 256 + + ++ Y+ L +I ++ G T+++ + FL+ +Q + Sbjct: 190 HSQTDSLEDEEIEAFYKML----TQRVEIDRTFAEAAGPGETLSVDQLVTFLQHQQREEA 245 Query: 257 GDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLS 316 + S I Y + + T F+ L S S + + +V QDM +PLS Sbjct: 246 AGPALALS-LIERY-EPSETTKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQPLS 303 Query: 317 HYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTK 376 HY +SSSHNTYL DQ + SS EAY+R L GCRC+ELDCWDGP+ P IYHG+T T+K Sbjct: 304 HYLVSSSHNTYLLEDQLAGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSK 363 Query: 377 IRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET 436 I F DVLR I+++AF S YP+ILS+E++C+L QQR MA + G +LL P+D Sbjct: 364 ILFCDVLRAIRDYAFKASPYPVILSLENHCTLEQQRVMARHLHAILGPMLLNRPLDGVTN 423 Query: 437 SLPSP 441 SLPSP Sbjct: 424 SLPSP 428 Score = 196 bits (477), Expect = 4e-48 Identities = 112/272 (41%), Positives = 161/272 (59%), Gaps = 11/272 (4%) Query: 933 RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 R+A+E+SD++IYC+SV F G + EM+SF E +A RL+ + N F V+++ Sbjct: 487 RLAQELSDMVIYCKSVHFGGFSSPGTPGQAFYEMASFSENRALRLLQESGNGF-VRHNVG 545 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 LSRIYP G R DSSNY+PV WN G Q+VALN+QTP M V +F+ NG CG++LKP Sbjct: 546 HLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYQDRFQDNGACGYVLKP 605 Query: 1052 QFMFEEG--YNPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS---PFVEVEIIGA 1105 F+ + +NP + +G + +RVI + L K + S P V VEI G Sbjct: 606 AFLRDPNGTFNP--RALAQGPWWARKRLNIRVISGQQLPKVNKNKNSIVDPKVTVEIHGV 663 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 D + T +++NG NP W+ FEV P+LALIRF+V+D D + +FIGQ+T P Sbjct: 664 SRDVASR-QTAVITNNGFNPWWDTEFAFEVVVPDLALIRFLVEDYDASSKNDFIGQSTIP 722 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L L++GYR V L + ++ +TL V +S+ Sbjct: 723 LNSLKQGYRHVHLMSKNGDQHPSATLFVKISL 754 >UniRef50_Q4RX70 Cluster: Chromosome 11 SCAF14979, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 11 SCAF14979, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1158 Score = 225 bits (550), Expect = 6e-57 Identities = 113/293 (38%), Positives = 181/293 (61%), Gaps = 9/293 (3%) Query: 152 WLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFA 209 WL++ F + + + +++ EV L K+N + K+R +FQD DT E +G +GF++F Sbjct: 159 WLQQTFSEADKNRDGTLSIGEVHQLLHKLNVNLPKQKVRQMFQDADTDENQGSLGFEEFC 218 Query: 210 VLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269 Y K+I ++ I YS + + L + +FL +EQ G + + + Sbjct: 219 SFY-KMISTRRDLYLIMISYS---NQKEVMDLHDLAHFLENEQKMR-GLTKEHLADIVAK 273 Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLT 329 + P+ ++ + F + S I++ ++++V QDMT+PL+HY+I++SHNTYL+ Sbjct: 274 FEPCPE-NLQHMVLGIDGFTNFMRSPAGDIFNPEHNEVNQDMTQPLNHYFIATSHNTYLS 332 Query: 330 GDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389 GDQ S+S +E Y L++GCRC+E+DCWDGPDG P I+HG+TLT+KI F DV+ TI +H Sbjct: 333 GDQLLSQSRVEMYAYVLQAGCRCVEVDCWDGPDGEPIIHHGYTLTSKILFKDVIETINKH 392 Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSP 441 AF S+YP+ILSIE++CS+PQQ++MA ++V D L + + N+ LPSP Sbjct: 393 AFTKSQYPVILSIENHCSVPQQKKMAEYLKEVLQDKLDLSVVISNDCKRLPSP 445 Score = 175 bits (427), Expect = 5e-42 Identities = 98/248 (39%), Positives = 146/248 (58%), Gaps = 14/248 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYN-EMSSFPETKAERLMSQQENTFF 985 K +T R+++ +SDL+ Y +SV + + + F + ++SS ET +++ Q + + Sbjct: 599 KKRKTMRLSRALSDLVKYTKSV--RVHDIETQAFTNSWQVSSLNETVMNQII-QLKPSEL 655 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 V+ + QL R+YP R+DSSN+NP P+WN G MVALNYQT + +++N KF NG C Sbjct: 656 VRLNQRQLLRVYPSNYRVDSSNFNPQPYWNTGCHMVALNYQTEGRMLELNRAKFSANGNC 715 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098 G+ILKP+ M + +NP + + G+ K ++L+VI + L K RG PFV Sbjct: 716 GYILKPKCMRKGAFNPTLEDPLPGRRK-TQLVLKVISGQQLPKPKDSMFGDRGEIIDPFV 774 Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158 EVEIIG D K T+ V DNG NP+W + F + P++AL+RF V D D G+ +F Sbjct: 775 EVEIIGLPMDCS-KQQTRVVEDNGFNPMWEETLVFNIQMPQVALVRFQVWDHDPIGQ-DF 832 Query: 1159 IGQATFPL 1166 IGQ T L Sbjct: 833 IGQRTIAL 840 >UniRef50_Q4SNU6 Cluster: Chromosome 15 SCAF14542, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15 SCAF14542, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 828 Score = 223 bits (546), Expect = 2e-56 Identities = 144/450 (32%), Positives = 224/450 (49%), Gaps = 34/450 (7%) Query: 16 EADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDV 75 E D + ++ +GS +LK R + R ++ + + +W + +LD D+ Sbjct: 3 EGDLDLDFLLKGSDLLKVRSRNWKKTRYFKLQEDC-KTMWLESKKLIKSNQTFSLD--DI 59 Query: 76 KEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLY 135 VR G+ ++ + EE ++E +CF+I + + + + +A +D+E WV + Sbjct: 60 SAVRVGRQTEGLRKSTEE--QVED-RCFSIVF--KGRRKNLDLIAGSDEEARRWVSSLQK 114 Query: 136 LIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQD 194 L++ + S + E W+ + N +K+T E+K FL IN ++ +FQ Sbjct: 115 LVSNLNNLSRKQKTEHWILSCLRKADKNKDDKLTQSEMKNFLRLINIEVDDIYAEMLFQK 174 Query: 195 VDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHD 254 D K G + ++ Y L E +I Y Y ++ FL EQ + Sbjct: 175 CDKSKSGYLAGEEIEHFYDLLTHRE----EINVIYGAYARTTGFMSPENLVEFLMKEQRE 230 Query: 255 ------------NLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSE--------FVEMLYS 294 N DE S F L P D T+ E F+ L+ Sbjct: 231 KATLADANSIIKNFEPDENGESSFFYPLLSGPDPDSRLRVPTVKEKQLLSKDGFLLYLHH 290 Query: 295 KQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIE 354 + I ++++ +V QDM+RPLSHY+ISSSHNTYL DQ SS EAYVR L+ GCRC+E Sbjct: 291 PETMILNAEHKEVYQDMSRPLSHYFISSSHNTYLMEDQLKGPSSTEAYVRALQKGCRCVE 350 Query: 355 LDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRM 414 LDCWDG D P IYHG+TLT++I F D ++ IK++AF S+YP+ILS+E++CS+ QQ+ M Sbjct: 351 LDCWDGSDNEPVIYHGYTLTSQILFKDAVKAIKDYAFQASDYPVILSLENHCSVKQQQVM 410 Query: 415 ASAFQDVFGDLLLVHPM-DKNETSLPSPHD 443 A + G L+ P+ D T PSP + Sbjct: 411 AHHLSSILGSALVTSPLGDTMPTDFPSPEE 440 Score = 120 bits (289), Expect = 2e-25 Identities = 64/136 (47%), Positives = 84/136 (61%), Gaps = 15/136 (11%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 ++AKE+SD++IYC+SV F+ K + EMSSF E KA +L + N + ++++ + Sbjct: 492 KLAKELSDMVIYCKSVHFSGFEDARKNLSFYEMSSFKEGKAVKLAEESANEY-IRHNAEK 550 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQM--------------VALNYQTPDKPMQVNMGK 1038 LSRIYP G R DSSNYNPVP WN G QM VALN+QT M VN G+ Sbjct: 551 LSRIYPAGVRTDSSNYNPVPLWNAGCQMGTGCSPKPQGLRSKVALNFQTACSDMDVNQGR 610 Query: 1039 FKQNGGCGFILKPQFM 1054 F+ NG G+ILKP FM Sbjct: 611 FQVNGKSGYILKPAFM 626 >UniRef50_UPI000069F421 Cluster: phospholipase C delta 3; n=1; Xenopus tropicalis|Rep: phospholipase C delta 3 - Xenopus tropicalis Length = 790 Score = 220 bits (537), Expect = 2e-55 Identities = 125/370 (33%), Positives = 205/370 (55%), Gaps = 16/370 (4%) Query: 75 VKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVL 134 ++ VR G S+ +++ +R + CFTI + + + + A ++KE WV+G+ Sbjct: 66 IESVREGHQSEGLQKYG---RRFPETCCFTIAF--KGRRKNLDLAASSEKEALNWVQGLQ 120 Query: 135 YLIAEAVSASYPLQIERWLRKEFY--SIENSHEKITLKEVKAFLPKINCKISTSKLRDVF 192 L+ A + S ++ ++ ++ + + EK+T +EVK L IN ++ ++F Sbjct: 121 KLMKRAEAMSQREKLVQYPVNDYLRQADRDGDEKMTFQEVKDMLKMINIDLNDIYAYNLF 180 Query: 193 QDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252 + D + + KL+ V++IF YS ++ E Q FL+ + Sbjct: 181 KACDRSNTNTLEDHEIEEFCTKLMH-RPEVEEIFHHYS---GEDRVLSAEELQEFLQAQG 236 Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312 D + +A + I+ Y + ++ + F+ L S I++ ++ QDMT Sbjct: 237 EDATLE---RAKELIQKYELNETAKQHD-LMMMEGFMMYLLSDDGDIFNQKHRMAYQDMT 292 Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT 372 +PL HY+ISSSHNTYLT Q ESS E+Y+R GCRC+ELDCW+GP G P IYHGHT Sbjct: 293 QPLCHYFISSSHNTYLTNHQLVGESSTESYIRVFMEGCRCVELDCWEGPSGEPVIYHGHT 352 Query: 373 LTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432 LT+KI F DV+ TI+++AF S YP+ILS+E++C L QQ +MA+ +++ GD+L+ P+ Sbjct: 353 LTSKILFKDVVTTIRDYAFKNSPYPVILSLENHCGLEQQVKMANHLREILGDMLVTKPVP 412 Query: 433 KNETS-LPSP 441 +T+ LPSP Sbjct: 413 GADTARLPSP 422 Score = 200 bits (489), Expect = 1e-49 Identities = 117/269 (43%), Positives = 159/269 (59%), Gaps = 19/269 (7%) Query: 935 AKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994 AKE+SDL++YC++V + + G V EMSSF E K RL+ + V+Y+ QLS Sbjct: 526 AKELSDLVVYCQTVEYRGQ----PGNVC-EMSSFSEDKVRRLI-KDSGINLVRYNARQLS 579 Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054 RIYP G R +SSNY P WN G Q+VALN+QTP M +N G+F+ NG CG++LKP+F+ Sbjct: 580 RIYPDGLRANSSNYCPQEMWNAGCQLVALNFQTPGYTMDLNRGRFQDNGLCGYVLKPEFL 639 Query: 1055 FEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVEIIGADYD 1108 +E +NP D S E P + ++VI A+ L K + PFV VEI G Sbjct: 640 RKEDSYFNP-DSPSKE----PKLLFVKVISAQQLPKLNKEKPNSIVDPFVRVEIHGVGKK 694 Query: 1109 SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168 + TK + +NG NP WN+I + EV PELAL+RFVV+D D +F+GQ T P L Sbjct: 695 K--EKETKYILNNGFNPYWNEILQLEVQVPELALVRFVVEDYDKTSSNDFVGQYTLPFLS 752 Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L++GYR V L + L +TL V + I Sbjct: 753 LKQGYRHVHLLSKDGASLSPATLFVQIRI 781 >UniRef50_Q5QIB9 Cluster: Phospholipase C delta isoform; n=6; Strongylocentrotus purpuratus|Rep: Phospholipase C delta isoform - Strongylocentrotus purpuratus (Purple sea urchin) Length = 753 Score = 219 bits (536), Expect = 3e-55 Identities = 136/474 (28%), Positives = 232/474 (48%), Gaps = 26/474 (5%) Query: 16 EADQLISYIERGSTVLKFFPRKRPER-RALCVRRETHQVLWSRINAPQRQGYEGALDIRD 74 + +Q+ ++RG+ K P + R + + ++++ ++ + + + + Sbjct: 7 QVEQIHQKLKRGTKFTKISPNSTKKHGRTFSLTDDGTALMYT---PSKKSSSKATVSLSE 63 Query: 75 VKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVL 134 + E+R+G + F R + K+ + F++ G E + VA + + WV G+ Sbjct: 64 IHEIRSGHETDTF-RISKNKKKYPKERSFSLIVGNEN--HTVNLVAPSQDDARTWVMGLR 120 Query: 135 YLIAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQ 193 +L ++ + W+ F + + + E L K+N KI + +FQ Sbjct: 121 WLKKKSQHIDIHSKQAAWIMDAFRQADVDRDGTVDFDESYKLLKKLNIKIEKVHAKRLFQ 180 Query: 194 DVDTE----KRGEIGFD----DFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245 +T K+G++ D D V + ++I ++Q++F KYS + T EF Sbjct: 181 FANTHSTTTKKGKVRSDALSEDEFVEFYRIITRRPDLQEVFKKYS---GDDDYWTPEEFA 237 Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFVEMLYSKQNSIYDSQY 304 F+ +EQ E A+ I +Y +P ++ + T+ F + I++ + Sbjct: 238 EFMHEEQKRLEVTPEWCATN-IEEY--EPNQEFRDQKILTMDGFFLFMMGPSGLIFNPFH 294 Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT 364 + V QDM +PL+HY+I+SSHNTYL DQ SS EAY+ L+ GCRC+ELDCWDGPD Sbjct: 295 EDVYQDMKQPLAHYFINSSHNTYLLDDQLRGPSSTEAYISALQRGCRCVELDCWDGPDND 354 Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P +YHGHTLT+KI+F D++ + ++AF SEYPLILS E++CS+ QQ+ MA + D Sbjct: 355 PIVYHGHTLTSKIKFRDIIEVVDKYAFAASEYPLILSFENHCSVEQQKVMAQICVSILKD 414 Query: 425 LLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGA---EESSFAVRQEEGKDLD 475 L + NE + PSP + P A E+ ++E D+D Sbjct: 415 KLYTNNNLHNEAAFPSPEELKGKILIKGKSLPPSAATTEDDGEVSDEDEAADID 468 Score = 179 bits (436), Expect = 4e-43 Identities = 107/269 (39%), Positives = 152/269 (56%), Gaps = 12/269 (4%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 ++AKE+SDL+ SV + + + ++MSSF E KA L + + V+++ Sbjct: 490 KLAKELSDLVTLA-SVHYGSFPASKEKYKCHQMSSFGEAKAFGLAEDKPGDY-VEHNKIF 547 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 LSRIYP G R +SSNY+PVP W+ G+Q+VALN+QTP + M +N GKF QNG GFILKP Sbjct: 548 LSRIYPGGLRTNSSNYSPVPMWDVGAQIVALNFQTPCEEMDLNQGKFLQNGKSGFILKPV 607 Query: 1053 FMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEVEIIGADYD 1108 F + +NP G V L VI + L K + P+V+V ++G Sbjct: 608 FCRKPNMQFNPLK----PGDQYTQHVTLTVISGQQLPKPSGSKEVIDPYVKVYVLGG--G 661 Query: 1109 SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168 S + T+ V +NG +P WN FEV PELALIR VVQD D+ FIGQ TFP+ Sbjct: 662 SKQEFKTEVVENNGFSPTWNQEFSFEVKVPELALIRLVVQDYDMASSNEFIGQYTFPVAS 721 Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 ++ GY VP+ ++L ++L +H + Sbjct: 722 MQLGYHHVPILGEKGDDLLPASLFIHTMV 750 >UniRef50_UPI00006609DC Cluster: Homolog of Brachydanio rerio "Phospholipase C gamma 1.; n=3; Euteleostomi|Rep: Homolog of Brachydanio rerio "Phospholipase C gamma 1. - Takifugu rubripes Length = 304 Score = 217 bits (531), Expect = 1e-54 Identities = 97/184 (52%), Positives = 135/184 (73%), Gaps = 2/184 (1%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 +MER +IA E+S+L++YCR V FN +++ Y +MSSFPETKAE+ ++ F+ Sbjct: 123 QMERRKKIAVELSELVVYCRPVPFNEDKIGTDRACYKDMSSFPETKAEKFTTRSRGKRFL 182 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +Y+ QLSR+YP+GQR+DSSNY+P+P W CGSQ+VALN+QTPDKPMQ+N F GG G Sbjct: 183 QYNRRQLSRVYPRGQRLDSSNYDPLPMWLCGSQLVALNFQTPDKPMQLNQAFFLLGGGSG 242 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGAD 1106 ++ +P M ++ ++P DK ++ V+P+T+ L+V+GARHL K GR PFVEVEI GAD Sbjct: 243 YVPQPDVMRDDIFDPFDKDTV--TVEPITIQLQVLGARHLPKNGRSIVCPFVEVEICGAD 300 Query: 1107 YDSG 1110 YDSG Sbjct: 301 YDSG 304 Score = 97.5 bits (232), Expect = 2e-18 Identities = 40/74 (54%), Positives = 54/74 (72%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 T++ TVKALYDYRA+++DEL F K A++ NVDK + GWWRGDYGGK+ WFPANYV E+ Sbjct: 48 TARCTVKALYDYRAQREDELCFPKQALVLNVDKQEGGWWRGDYGGKKQLWFPANYVEELP 107 Query: 836 VPHTPDVTSGLENE 849 ++ ++ E Sbjct: 108 SSPVRELDEAMQEE 121 >UniRef50_Q86XJ2 Cluster: PLCH2 protein; n=8; Euteleostomi|Rep: PLCH2 protein - Homo sapiens (Human) Length = 1238 Score = 216 bits (527), Expect = 3e-54 Identities = 107/294 (36%), Positives = 177/294 (60%), Gaps = 9/294 (3%) Query: 151 RWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEK-RGEIGFDDF 208 +WL++ F + N +++ EV L K+N + +++ +F++ DT+ +G +GF++F Sbjct: 30 KWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEF 89 Query: 209 AVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIR 268 Y+ + + +D++ Y ++ + Q FL+ EQ + +++ Q I Sbjct: 90 CAFYKMM----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDII 143 Query: 269 DYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYL 328 + + + + F S I++ ++ V QDMT+PLSHY+I+SSHNTYL Sbjct: 144 EQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYL 203 Query: 329 TGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKE 388 GDQ S+S ++ Y L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F DV+ TI + Sbjct: 204 VGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINK 263 Query: 389 HAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSLPSP 441 +AFI +EYP+ILSIE++CS+ QQ++MA D+ GD L L ++ T+LPSP Sbjct: 264 YAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSP 317 Score = 86.6 bits (205), Expect = 4e-15 Identities = 43/104 (41%), Positives = 68/104 (65%), Gaps = 5/104 (4%) Query: 927 KMERTWRIAKEISDLIIYCRSV-TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 + ++T ++++ +SDL+ Y +SV T +IE + ++SSF ETKA +++ QQ+ + Sbjct: 473 RQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSW---QVSSFSETKAHQIL-QQKPAQY 528 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPD 1029 ++++ QLSRIYP R+DSSNYNP PFWN G QM N + D Sbjct: 529 LRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMGVFNPNSED 572 Score = 83.0 bits (196), Expect = 4e-14 Identities = 55/146 (37%), Positives = 78/146 (53%), Gaps = 15/146 (10%) Query: 1059 YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRGTA-SPFVEVEIIGADYDSGV 1111 +NP + + G++K V LR+I + L K RG PFVEVEIIG D Sbjct: 566 FNPNSEDPLPGQLKKQLV-LRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIGLPVDCS- 623 Query: 1112 KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171 + T+ V DNG NP W + F V PE+AL+RF+V D D G +FIGQ T + Sbjct: 624 REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGR-DFIGQRTLAFSSMMP 682 Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197 GYR V + E +E +++ VH+++ Sbjct: 683 GYRHV-----YLEGMEEASIFVHVAV 703 >UniRef50_UPI000065E113 Cluster: Homolog of Homo sapiens "PhosPholiPase C-like 3; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "PhosPholiPase C-like 3 - Takifugu rubripes Length = 1130 Score = 215 bits (524), Expect = 8e-54 Identities = 111/293 (37%), Positives = 177/293 (60%), Gaps = 9/293 (3%) Query: 152 WLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFA 209 WL++ F + N +++ EV L K+N + K+R +FQD DT E +G +GF++F Sbjct: 162 WLQQTFSEADKNGDGTLSIGEVHQLLHKLNVNLPKQKVRQMFQDADTDENQGSLGFEEFC 221 Query: 210 VLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269 Y K+I ++ I YS + + L + FL +EQ G + + Sbjct: 222 SFY-KMISTRRDLYLIMISYS---NQKEVMDLHDLARFLENEQKMR-GLTKEHLVDIVAK 276 Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLT 329 + P+ ++ + F + S I++ ++++V QDMT+ L++Y+I++SHNTYL+ Sbjct: 277 FEPCPE-NLQHMVLGIDGFTNFMRSPAGDIFNPEHNQVNQDMTQALNNYFIATSHNTYLS 335 Query: 330 GDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389 GDQ S+S +E Y L++GCRC+E+DCWDGPDG P I+HG+TLT+KI F DV+ TI ++ Sbjct: 336 GDQLLSQSRVEMYAYVLQAGCRCVEVDCWDGPDGEPIIHHGYTLTSKILFKDVIETIDKY 395 Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE-TSLPSP 441 AF S+YP+ILSIE++CS+PQQ++MA ++V D L + + N+ LPSP Sbjct: 396 AFTKSQYPVILSIENHCSVPQQKKMAEYLKEVLQDKLDLSVVISNDCKKLPSP 448 Score = 182 bits (444), Expect = 4e-44 Identities = 99/248 (39%), Positives = 147/248 (59%), Gaps = 14/248 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYN-EMSSFPETKAERLMSQQENTFF 985 K +T R+++ +SDL+IY +SV + + + F + ++SS ET +++ Q + Sbjct: 573 KKRKTMRLSRALSDLVIYTKSV--RVHDIETQAFTNSWQVSSLNETVMNQIL-QLKPDHL 629 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 V+++ QL R+YP R+DSSN+NP P+WN G MVALNYQT + +++N KF NG C Sbjct: 630 VRFNQRQLLRVYPSNYRVDSSNFNPQPYWNTGCHMVALNYQTEGRMLELNTAKFSANGNC 689 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFV 1098 G+ILKP++M + +NP + + G+ K ++L++I + L K RG PFV Sbjct: 690 GYILKPKYMRKGAFNPTLEDPLPGRRK-TQLVLKIISGQQLPKPKDSMLGDRGEIIDPFV 748 Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158 EVEIIG D K T+ V DNG NP+W + F + PE+AL+RF V D D G +F Sbjct: 749 EVEIIGLPLDCS-KQQTRVVDDNGFNPMWEETLVFNIQMPEVALVRFQVWDHDPIGR-DF 806 Query: 1159 IGQATFPL 1166 IGQ T L Sbjct: 807 IGQRTIAL 814 Score = 49.6 bits (113), Expect = 5e-04 Identities = 40/158 (25%), Positives = 74/158 (46%), Gaps = 11/158 (6%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P ++ + + I ++EV GK S+ F R+ + R + + CF+IY+G +++ V Sbjct: 41 PSKKQDKAKITIDSIQEVCEGKKSEMFRRYADN--RFDPNCCFSIYHGE--RVKSLDLVT 96 Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKA---FLP 177 +E WV G+ YL+A +S L R ++ Y + + TLK + + + Sbjct: 97 TNAEEARTWVTGLKYLMA-GISDEDSL-ARRQRTRDQYPLSSLCCTNTLKNILSRSWSVF 154 Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKL 215 ++NC S + L+ F + D G + + L KL Sbjct: 155 RLNC--SVTWLQQTFSEADKNGDGTLSIGEVHQLLHKL 190 >UniRef50_O97037 Cluster: PLC-deltaH; n=1; Hydra magnipapillata|Rep: PLC-deltaH - Hydra magnipapillata (Hydra) Length = 738 Score = 212 bits (518), Expect = 4e-53 Identities = 131/386 (33%), Positives = 197/386 (51%), Gaps = 17/386 (4%) Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 P +G + I D+ ++ +S FE K+L T Y E K F Sbjct: 57 PSVKGSNFKILIADITDINVAES---FETKICFKKKLLHQFIVT-YKDDENKTHKLGFFV 112 Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKI 179 + E W G+ YL E P+ ++ WLR+ F + + N + + LKE+ L + Sbjct: 113 EDQNEVRFWSSGLQYLSDELKKPEDPI-VDDWLREAFDAADVNKNSLLGLKEISQLLNSL 171 Query: 180 NCKISTSKLRDVFQDVDTEKR----GEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSN 235 N S ++ FQ+ E++ G++ + FA ++ FD+N V I +Y Sbjct: 172 NISKENSDVKLKFQECCNEEKNNENGKLTRNGFAEFFKFFSFDKNEVSSIIKEYGRTIFG 231 Query: 236 GTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSK 295 T + Q + R+ Q NL +E + + I + D R Y + + ML S+ Sbjct: 232 KTCLNAESLQKYFREVQQQNLSLEECK--KIISKH--DENRG---SYLSAEGVIRMLISE 284 Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355 +N I D + + QDMTRPL+ Y+I+SSHNTYL DQ SS +AY + L+ GC+ +EL Sbjct: 285 ENDILDPIHKNIHQDMTRPLTDYFINSSHNTYLLNDQVLGMSSTKAYEKALKKGCKTLEL 344 Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415 DC+DG + P +YHG TLT+KI F DV+ TI AF+ SEYP+ILS E++CS QQ MA Sbjct: 345 DCYDGENNEPIVYHGFTLTSKILFKDVIDTIAMGAFVQSEYPVILSFENHCSPEQQIVMA 404 Query: 416 SAFQDVFGDLLLVHPMDKNETSLPSP 441 ++ G +L +D N+T LPSP Sbjct: 405 QHLKEKLGKMLFDGDVDLNQTKLPSP 430 Score = 173 bits (420), Expect = 3e-41 Identities = 101/273 (36%), Positives = 148/273 (54%), Gaps = 9/273 (3%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 K ++ +AKE S++I Y S+TF + Y + S E K +L + E + Sbjct: 465 KTKQKINVAKEFSNIINYVESITFKSLDEGLATQKYFQNVSLGEKKLLQL-GRDEPKKLI 523 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +Y L R YPKG RIDSSNYNP W G Q+VALN+QTP + M +N G F NG CG Sbjct: 524 EYSNKFLVRTYPKGSRIDSSNYNPTKGWVYGCQIVALNFQTPGEMMDINDGMFALNGKCG 583 Query: 1047 FILKPQFMFEEGYNPCD-KKSIEGKVKPVTVMLRVIGARHLCKTGRGTA--SPFVEVEII 1103 ++LKP+ + ++P + KSI G K V +++I L K + P++ + I Sbjct: 584 YVLKPECLRSGNFDPQNIDKSINGVCK---VFIKIISGHLLPKASKDETIPDPYIRINIH 640 Query: 1104 GADYDSGV-KLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 G D + K +TK V NG NP WN+ +F++ PELA IRF + D D+ G +FIGQ Sbjct: 641 GIPKDEVLGKFITKKVKRNGFNPQWNEDFQFDLYAPELAHIRFALCDSDM-GVDDFIGQY 699 Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 + P +R GYR VPL ++ ++ +V + Sbjct: 700 SIPFSAIRTGYRRVPLLKRSGHPIKNASFLVFI 732 >UniRef50_P40977 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1; n=1; Schizosaccharomyces pombe|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 - Schizosaccharomyces pombe (Fission yeast) Length = 899 Score = 212 bits (517), Expect = 6e-53 Identities = 128/390 (32%), Positives = 201/390 (51%), Gaps = 37/390 (9%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129 L + D+KE+R G+ ++++ + + E + FTI Y + KL+ ++ T W Sbjct: 206 LCVDDIKEIRQGRDARNYREQYKISSENEK-RWFTIIYCADNKLKAMHMISPTLDAHNQW 264 Query: 130 VKGV----LYLIAEAVSA------------SYPLQIERWLRKEFYSIENSHEKITLKEVK 173 + + Y + E + Y + W + E + ++ L +V Sbjct: 265 IMALEGLKTYRLNEFIIGLNLVCHQGEKMIDYSENLNPWEKLE----KEQSAQLDLGDVH 320 Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYC 233 ++ S L + FQ D + G++ F++F + L+ + + DIF +Y+ Sbjct: 321 RMCQMLHLNASMEFLEETFQKADADHSGKLSFEEFQH-FVSLLKTRSEIVDIFKEYT--- 376 Query: 234 SNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLY 293 S ++L +F++FL Q L D ++ Y+ D + L EF L Sbjct: 377 SGSDKMSLEQFRHFLSTSQKARLDSDSIRTL-----YVSFCSND--DSKMGLIEFTSFLL 429 Query: 294 SKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCI 353 S NS V QDM+RPL+ Y ISSSHNTYL G QF ESS+E Y+R L+ GC+CI Sbjct: 430 SPHNS----PVVPVIQDMSRPLNEYLISSSHNTYLLGKQFGGESSIEGYIRSLQRGCKCI 485 Query: 354 ELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRR 413 E+DCWDGP+G P + HGHT T+ I+F DV+ I+++AF+ S YPL +S+E +C QQR+ Sbjct: 486 EIDCWDGPNG-PVVCHGHTFTSMIKFNDVIDAIRKYAFVVSPYPLFISLEIHCCPDQQRQ 544 Query: 414 MASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 M S + FGD L++ P+ NE+ LPSP D Sbjct: 545 MVSYMKQAFGDTLVMKPVTANESVLPSPED 574 Score = 108 bits (259), Expect = 1e-21 Identities = 75/268 (27%), Positives = 131/268 (48%), Gaps = 13/268 (4%) Query: 934 IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQL 993 I +E+ L Y RS+ F L + Y+ + SF E ++ + K++ L Sbjct: 634 IVQELQQLAPYARSLKFRNFSLP-ESKTYSHIFSFSERTIKK-HGKAMVPRLSKHNLRYL 691 Query: 994 SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053 R+YP R+ S+N+NP +W G QMVALN+QT D +Q+N F + G++LKP Sbjct: 692 CRVYPGPLRVGSTNFNPQVYWRLGVQMVALNWQTYDTGLQINDALFIADPPTGYLLKPPC 751 Query: 1054 MFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRGTASPFVEVEIIGADYDS 1109 G + EG + + + + VI + L + + T SP+VE+++ + +S Sbjct: 752 QRIIGTTVGE----EGLPRKIKLTIDVISGQQLRRARELSNSETLSPYVEIQVHSME-ES 806 Query: 1110 GVKLVTKTVSDNGLNPLWNDICEFE--VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167 + +K V +NG P W + +E +++ ++IRF+V G + T P+ Sbjct: 807 PFRWCSKVVHENGFRPFWGETMVYESIISDDFYSMIRFLVHHRGSNGNDSIFANFTCPID 866 Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHL 1195 L++GYR + L + E L S+L + + Sbjct: 867 RLQQGYRHIRLLDMQGENLLFSSLFLKI 894 >UniRef50_Q9UPR0 Cluster: Inactive phospholipase C-like protein 2 (Phospholipase C epsilon 2) (Phospholipase C-L2) (PLC-L(2)); n=58; Eumetazoa|Rep: Inactive phospholipase C-like protein 2 (Phospholipase C epsilon 2) (Phospholipase C-L2) (PLC-L(2)) - Homo sapiens (Human) Length = 1127 Score = 211 bits (515), Expect = 1e-52 Identities = 141/453 (31%), Positives = 231/453 (50%), Gaps = 27/453 (5%) Query: 2 KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 K+V F+ ++ I A I+ + GS + K R R + + + W Sbjct: 120 KTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWE---- 175 Query: 61 PQRQGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119 P ++ E A +DI+ +KEVRTGK++ D R + ++ F++ YG ++ V Sbjct: 176 PSKKDSEKAKIDIKSIKEVRTGKNT-DIFRSNGISDQISEDCAFSVIYGENYE--SLDLV 232 Query: 120 AQTDKECEAWVKGVLYLIA------EAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEV 172 A + WV G+ YLI+ + + +S W+ + F I+ ++ ITL Sbjct: 233 ANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNA 292 Query: 173 KAFLPKINCKISTSKLRDVFQDV--DTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFDKY 229 + +N + TSK+ F+++ +K G E+ ++F ++ +L +I+ Sbjct: 293 VQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELC----TRPEIYFLL 348 Query: 230 SVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEF 288 + SN + ++ FL EQ ++E+ + I Y +P ++ E + ++ F Sbjct: 349 VQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISL-EIIHKY--EPSKEGQEKGWLSIDGF 405 Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348 L S I+D ++ KV QDM +PLSHY+I+SSHNTYL DQF S + Y+R L+ Sbjct: 406 TNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKM 465 Query: 349 GCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSL 408 GCR +ELD WDGPD P IY GHT+T++I F V+ I ++AF SEYPLIL +E++CS+ Sbjct: 466 GCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSI 525 Query: 409 PQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 QQ+ M + + GD L + E+ LPSP Sbjct: 526 KQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSP 558 Score = 196 bits (478), Expect = 3e-48 Identities = 109/275 (39%), Positives = 164/275 (59%), Gaps = 11/275 (4%) Query: 930 RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989 + +++ KE+S+L+ C+SV F ++ + Y E+ SF E A + ++ F V Y+ Sbjct: 610 KRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDF-VNYN 668 Query: 990 TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049 L+R++P RIDSSN NP FW CG Q+VA+N+QTP M +N+G F+QNG CG++L Sbjct: 669 KRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVL 728 Query: 1050 KPQFMFEE--GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEI 1102 +P M EE ++ K S+ G V P + +++I ++ K G G P+V VEI Sbjct: 729 RPAIMREEVSFFSANTKDSVPG-VSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEI 787 Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 G D + TKTV NG P++++ EF++ PELA++RFVV D+D G+ FIGQ Sbjct: 788 HGIPADCAEQR-TKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQY 845 Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 T P CL+ GYR VPL + E L ++L VH++I Sbjct: 846 TIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAI 880 >UniRef50_A7SDH9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 665 Score = 210 bits (513), Expect = 2e-52 Identities = 116/350 (33%), Positives = 185/350 (52%), Gaps = 21/350 (6%) Query: 95 KRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLR 154 K+ C ++ +G + R VA++ + W+ G+ LI + WL Sbjct: 8 KKYSLDTCISVKFGAD---RSLDLVAKSVETANLWLVGLQTLINNQSKCT-------WLI 57 Query: 155 KEFYSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGF--DDFAVL 211 F + N ++ L EV L +N I+ ++ F+ V + E ++FA Sbjct: 58 DAFEKFDKNKDGELGLSEVTKLLNALNVNITPKTIKKRFR-VSEQAGAEAALNKEEFAEF 116 Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271 + K I + + +I +K++ S + + + Q FL + + + Sbjct: 117 F-KAIATRDEIVEIMNKFT---SGKAHMNVEDLQKFLYKQGVKEVSKQYCDIIISTYEPT 172 Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331 + QRD + L SK+ I+D+ +DKV QDM +PLSHY+I+SSHNTYL D Sbjct: 173 EEGQRD---KQLGIDGLTNYLLSKEGDIFDTAHDKVYQDMRQPLSHYFIASSHNTYLMED 229 Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAF 391 Q SS++AY+ GCRC+ELDCWDG +G P +YHGHTLT+KI+F D+++ + EHAF Sbjct: 230 QLKGPSSVDAYINAFNKGCRCVELDCWDGDNGDPIVYHGHTLTSKIKFKDIIQAVAEHAF 289 Query: 392 ITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 S+YP+ILS+E++C++ QR++A +++ GD L P+D TSLPSP Sbjct: 290 KVSDYPVILSLENHCNIENQRKIAEHLENILGDKLFKDPVDTALTSLPSP 339 Score = 201 bits (490), Expect = 1e-49 Identities = 116/277 (41%), Positives = 168/277 (60%), Gaps = 13/277 (4%) Query: 929 ERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVK 987 E+ ++AKE+S + Y SV F N E + Y +MSSF E+K L +Q + FV+ Sbjct: 394 EKKVKLAKELSRCVNYISSVGFKNFEHSKENAKFY-QMSSFVESKVATL-AQNKAAGFVE 451 Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047 Y+T QLSR YP G R+DSSNYNP WN G Q+VALNYQT + M +N G+F++N G+ Sbjct: 452 YNTRQLSRTYPAGSRVDSSNYNPQVAWNVGCQIVALNYQTDGEYMHLNQGRFRENKRAGY 511 Query: 1048 ILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRG-TASPFVEV 1100 +LKP +M +NP + KS G VK ++++VI + L K + +G P+VEV Sbjct: 512 VLKPAYMRNPDIKFNPNNPKSCPG-VKKKLLIIQVISGQQLPKPQGSSSKGEVIDPYVEV 570 Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160 +I G + DS TK + DNG NP+WN+ + + PELA++RF V DED+ G+ +FIG Sbjct: 571 KIYGVNSDS-ADFKTKVIKDNGFNPVWNEEIKKLLYVPELAMLRFCVYDEDV-GKDDFIG 628 Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 Q + P+ LR GYR + L + E L ++L VH+ + Sbjct: 629 QFSLPITSLRTGYRHIHLLDIKGEPLPHASLFVHVML 665 >UniRef50_Q4RY83 Cluster: Chromosome 3 SCAF14978, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 3 SCAF14978, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 806 Score = 207 bits (505), Expect = 2e-51 Identities = 107/274 (39%), Positives = 163/274 (59%), Gaps = 10/274 (3%) Query: 928 MERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 M R++KE+SD ++YC+SV F + + RI Y E++SF E+KA + + ++ FV Sbjct: 537 MRSKQRLSKELSDCVVYCKSVHFRSFKHSRIHSKFY-EVASFTESKARKHL-REAGAEFV 594 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ QL+R+YP G R DSSN+NP WN G Q+VALN+QT + M +N G F+QNG CG Sbjct: 595 YHNSRQLTRVYPSGFRTDSSNFNPQEMWNAGCQIVALNFQTAGEGMDLNDGLFRQNGNCG 654 Query: 1047 FILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG---RGTASPFVEVE 1101 ++LKP FM E+ ++P + KP+ + ++VI + L K P V VE Sbjct: 655 YVLKPSFMRTAEKRFDP-ETPHKRDSYKPIVLTIQVISGQQLPKVNIKEDSIVDPLVRVE 713 Query: 1102 IIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQ 1161 I G D K T+ + +NG NP+W D F + PELA++RFVV+D D +F+GQ Sbjct: 714 IYGVPLDQ-AKQETRYIENNGFNPVWYDTLRFTIHTPELAMVRFVVEDYDKTSRNDFVGQ 772 Query: 1162 ATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 T PL C+++GYR + L + + ++L VH+ Sbjct: 773 YTLPLSCMQQGYRHIHLLSKDGTSIPPASLFVHI 806 Score = 200 bits (488), Expect = 2e-49 Identities = 101/252 (40%), Positives = 150/252 (59%), Gaps = 7/252 (2%) Query: 193 QDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252 Q D + G + D+F VL+ K++ +V +F +YS ++G ++ + ++FLR+EQ Sbjct: 237 QMADKSQSGTLEGDEF-VLFYKMLTQREDVLKVFQEYS---ADGQKLSQADLEDFLREEQ 292 Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312 + GD + A Q I Y + T F+ L S + SI++ + QD+ Sbjct: 293 FEE-GDIQHHAKQLIERYEPSDTAKLLNA-MTFDGFLMYLGSTEGSIFNPDRRGIFQDLG 350 Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT 372 +PL HY+I+SSHNTYL DQ SS+E Y+R L GCRC+E+DCWDG +G P +YHGHT Sbjct: 351 QPLCHYFIASSHNTYLMEDQLRGHSSVEGYIRALSRGCRCVEVDCWDGANGEPIVYHGHT 410 Query: 373 LTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432 T+KI F DV+ + +AF SEYP+ILS+E++C + QQ+ MA + GD LL + ++ Sbjct: 411 FTSKILFKDVVGAVANYAFKVSEYPVILSVENHCGVEQQKVMAQHLNHILGDKLLKNTLN 470 Query: 433 -KNETSLPSPHD 443 K T LPSP D Sbjct: 471 GKAPTGLPSPED 482 Score = 38.3 bits (85), Expect = 1.3 Identities = 48/272 (17%), Positives = 114/272 (41%), Gaps = 22/272 (8%) Query: 14 IHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIR 73 I E D L S + GS + K R ++R ++ + +W + + + + Sbjct: 6 IREDDNLQSMLV-GSVMRKIKSRTWKKQRYFKLQEDC-MTIWYK--SKKAGNSHSTFSVS 61 Query: 74 DVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGV 133 DV+ +R G S+ +E + +CFT+ + + + VA++ +E ++W++G+ Sbjct: 62 DVEAIREGHQSEVLLSIADE---FPADRCFTLVFRS--RRGNLDLVAESAEEAQSWIRGI 116 Query: 134 LYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQ 193 L+ + +++ W F+ + N ++ + + ++ + + D F+ Sbjct: 117 RKLVENLENMGEREKLDHW----FHGLTNVSNRV-IDWLANLGEDLSSSVLIRWISDWFK 171 Query: 194 DVDTEKRGEIGFDDFAVLYQKLIFD--ENNVQDIFDKYSVYCSNGTTI-TLR-----EFQ 245 D G + F + L + + D E++ +F S G ++ T++ +F+ Sbjct: 172 KADKNNDGRMNFKEVRDLLKMMNVDMSEHHAHRLFTVRPSDLSGGHSLDTVQRVPQPKFR 231 Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD 277 +F + D ++ +F+ Y QR+ Sbjct: 232 SFSLTQMADKSQSGTLEGDEFVLFYKMLTQRE 263 >UniRef50_UPI000069E9FD Cluster: phospholipase C, delta 4; n=1; Xenopus tropicalis|Rep: phospholipase C, delta 4 - Xenopus tropicalis Length = 781 Score = 205 bits (500), Expect = 7e-51 Identities = 112/272 (41%), Positives = 158/272 (58%), Gaps = 11/272 (4%) Query: 933 RIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 R++ +SD +IYC+SV F + + R +Y EMSS E KA +L+ + N F V+++ Sbjct: 510 RLSHLLSDCVIYCKSVPFVSFQHSRAHYTLY-EMSSVTEYKARKLVREPGNDF-VRHNAW 567 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 QL R+YP G R DSSNYNP WN G QMVALN+QT M +N G F+QN CG++LKP Sbjct: 568 QLMRVYPTGLRTDSSNYNPQEMWNVGCQMVALNFQTAGVEMDLNDGLFRQNARCGYVLKP 627 Query: 1052 QFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEVEIIGA 1105 FM E +NP +S EG PV + + VI A+ L K PFV VEI G Sbjct: 628 SFMRHVETTFNPDQPQSTEG-YSPVNLSILVISAQQLPKVENSKEGSIVDPFVRVEIFGV 686 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 D K TK + +NG NP+W + F++ PELAL+RFVV+D D +F+GQ T P Sbjct: 687 PIDQ-TKQETKYIENNGFNPMWYETLHFKIHVPELALVRFVVEDYDKTSRNDFVGQYTLP 745 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 ++ GYR + L + ++ +++ VH+ + Sbjct: 746 FKSIKSGYRHIHLLSRDGTKMPPASVFVHVRV 777 Score = 194 bits (472), Expect = 2e-47 Identities = 120/365 (32%), Positives = 191/365 (52%), Gaps = 19/365 (5%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTI-YYGTEFKLRCASFVAQTDKECEA 128 + I D++ VR G S+ + +E K CFTI ++G L VA T +E + Sbjct: 7 VSISDIETVREGHQSEVLQSIADEFK---PELCFTIVFHGRRANL---DLVANTPEEAQC 60 Query: 129 WVKGVLYLIAEAVSASYPLQIE----RWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKI 183 W++G+ LI + ++ RW+ F + N ++ KEV+ L +N + Sbjct: 61 WIQGLEKLIETVTNMDQKDLLDQYPFRWICDWFQKADKNKDGRMNFKEVQDLLKMMNVDM 120 Query: 184 STSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLRE 243 S +FQ D + G + ++F VL+ K + + V IF +S +G +TL E Sbjct: 121 SEHHAYRLFQMADKSESGTLEGEEF-VLFYKALTQRDEVLKIFQDFS---KDGKKLTLLE 176 Query: 244 FQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303 F +FL+ Q + +E+ R D + ++ ++ FV L S + SI++ Sbjct: 177 FVDFLQQGQLEEENTEELAMDLIARYEPSDTAKKLHA--MSIDGFVMYLCSPEGSIFNVA 234 Query: 304 YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG 363 ++++ QDMT+PL HY+ISSSHNTYL DQ +SS+E Y+R L+ GCRC+E+D WDGP+G Sbjct: 235 HEQLYQDMTQPLCHYFISSSHNTYLMEDQIRGQSSVEGYIRALKRGCRCVEVDTWDGPNG 294 Query: 364 TPFIYHGHTLTTKIRFMDVLRTIKEHAF-ITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 P +YHG T T+KI F DV+ I ++AF ++ PLI I ++ + AS + Sbjct: 295 EPIVYHGRTFTSKILFKDVISAINKYAFRVSGLLPLIYMIRAIGTMKGGGKFASFARAFL 354 Query: 423 GDLLL 427 G LL Sbjct: 355 GPRLL 359 >UniRef50_Q86YW0 Cluster: Phospholipase C zeta 1; n=7; Eutheria|Rep: Phospholipase C zeta 1 - Homo sapiens (Human) Length = 608 Score = 196 bits (479), Expect = 2e-48 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 K R +IA +SDL+IY ++ F + + R+ +NE +S ET+A +L + + F Sbjct: 338 KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 396 Query: 986 VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044 +HT + ++RIYPK R DSSN+NP FWN G QMVALN+QTP PM + GKF NGG Sbjct: 397 --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 454 Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100 G+ILKP F+ E +NP + K EG P+T+ +R+I L T V + Sbjct: 455 SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 510 Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160 E+ G D +K T+ + N +P WN+ F + PELALIRFVV+ + + F+G Sbjct: 511 EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 569 Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 Q T PLLC+ KGYR +PL + E LE ++L V++ Sbjct: 570 QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 604 Score = 196 bits (478), Expect = 3e-48 Identities = 102/277 (36%), Positives = 161/277 (58%), Gaps = 8/277 (2%) Query: 166 KITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDI 225 KI L++ + L K++ + S ++ +F+D D K+G I ++F +Y ++I + +I Sbjct: 18 KINLEKTQRLLEKLDIRCSYIHVKQIFKDNDRLKQGRITIEEFRAIY-RIITHREEIIEI 76 Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPY-FT 284 F+ YS N + FL EQ+ + A + I+ Y +P ++ + + + Sbjct: 77 FNTYS---ENRKILLASNLAQFLTQEQYAAEMSKAI-AFEIIQKY--EPIEEVRKAHQMS 130 Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344 L F + S++ ++ ++ KV QDMT PL+ Y+ISSSHNTYL DQ S L YV Sbjct: 131 LEGFTRYMDSRECLLFKNECRKVYQDMTHPLNDYFISSSHNTYLVSDQLLGPSDLWGYVS 190 Query: 345 CLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404 L GCRC+E+DCWDG P +YHG+TLT+K+ F V++ I ++AF+TS+YP++LS+E+ Sbjct: 191 ALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLEN 250 Query: 405 NCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 +CS QQ MA Q FG+ LL +D +LPSP Sbjct: 251 HCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 287 >UniRef50_Q08AQ7 Cluster: PLCZ1 protein; n=19; Amniota|Rep: PLCZ1 protein - Homo sapiens (Human) Length = 415 Score = 196 bits (479), Expect = 2e-48 Identities = 112/275 (40%), Positives = 160/275 (58%), Gaps = 14/275 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 K R +IA +SDL+IY ++ F + + R+ +NE +S ET+A +L + + F Sbjct: 145 KKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQ-QFNENNSIGETQARKLSKLRVHEFI 203 Query: 986 VKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044 +HT + ++RIYPK R DSSN+NP FWN G QMVALN+QTP PM + GKF NGG Sbjct: 204 --FHTRKFITRIYPKATRADSSNFNPQEFWNIGCQMVALNFQTPGLPMDLQNGKFLDNGG 261 Query: 1045 CGFILKPQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEV 1100 G+ILKP F+ E +NP + K EG P+T+ +R+I L T V + Sbjct: 262 SGYILKPHFLRESKSYFNPSNIK--EG--MPITLTIRLISGIQLPLTHSSSNKGDSLVII 317 Query: 1101 EIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160 E+ G D +K T+ + N +P WN+ F + PELALIRFVV+ + + F+G Sbjct: 318 EVFGVPNDQ-MKQQTRVIKKNAFSPRWNETFTFIIHVPELALIRFVVEGQGLIAGNEFLG 376 Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 Q T PLLC+ KGYR +PL + E LE ++L V++ Sbjct: 377 QYTLPLLCMNKGYRRIPLFSRMGESLEPASLFVYV 411 Score = 51.2 bits (117), Expect = 2e-04 Identities = 24/51 (47%), Positives = 33/51 (64%) Query: 391 FITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 F TS+YP++LS+E++CS QQ MA Q FG+ LL +D +LPSP Sbjct: 44 FKTSDYPVVLSLENHCSTAQQEVMADNLQATFGESLLSDMLDDFPDTLPSP 94 >UniRef50_UPI0000EB12AF Cluster: phospholipase C-like 3; n=1; Canis lupus familiaris|Rep: phospholipase C-like 3 - Canis familiaris Length = 1206 Score = 195 bits (476), Expect = 5e-48 Identities = 112/278 (40%), Positives = 162/278 (58%), Gaps = 19/278 (6%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + +T ++ +E+SDL++Y SV + + G N +S F ET+A +++ Q+ F + Sbjct: 218 RRRKTMKLCRELSDLVVYTNSVA--AQDIVDDGTTGNVLS-FSETRAHQVVQQKSEQFMI 274 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 Y+ QL+RIYP RIDSSN+NP+P+WN G Q+VALNYQ+ + MQ+N KFK NG CG Sbjct: 275 -YNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKTNGNCG 333 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099 ++LKPQ M + +NP + K ++L+VI + L K RG PFVE Sbjct: 334 YVLKPQQMCKGTFNPYSGDPLPANPKK-QLILKVISGQQLPKPPDSMFGDRGEIIDPFVE 392 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159 VEIIG D K T+ V DNG NP+W + F V P++AL+RF+V D D G +F+ Sbjct: 393 VEIIGLPVDC-CKDQTRVVDDNGFNPVWEETLTFTVHMPDIALVRFLVWDHDPIGR-DFV 450 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 GQ T L GYR V + E L +++ VH++I Sbjct: 451 GQRTVTFSSLVPGYRHV-----YLEGLTEASIFVHITI 483 Score = 49.2 bits (112), Expect = 7e-04 Identities = 23/47 (48%), Positives = 34/47 (72%), Gaps = 1/47 (2%) Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET-SLPSP 441 +P+ILSIE++CS+ QQR++A + +FGD L + +D ET LPSP Sbjct: 14 FPVILSIENHCSVQQQRKIAQYLKGIFGDKLDLSSVDTGETKQLPSP 60 >UniRef50_UPI00015B5A66 Cluster: PREDICTED: similar to phospholipase c epsilon; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to phospholipase c epsilon - Nasonia vitripennis Length = 1801 Score = 194 bits (473), Expect = 1e-47 Identities = 103/236 (43%), Positives = 140/236 (59%), Gaps = 8/236 (3%) Query: 211 LYQKLIFDENNVQDIFDKYS-VYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRD 269 L++K IFD I + S V S ITL F FL Q + L DDE++A I+ Sbjct: 739 LHKKQIFDAIAAASIVNNCSGVDTSKSQVITLATFTKFLESRQQEKLSDDEIKA--LIKR 796 Query: 270 YLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQ-DMTRPLSHYWISSSHNTYL 328 + DP + + F + K N + ++Y + +M +P+S Y+I+SSHNTYL Sbjct: 797 HEPDPALRT-QWCLSFEGFARYMMDKDNYAFPNEYALPAECEMQQPMSQYYIASSHNTYL 855 Query: 329 TGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKE 388 TG Q ESS++ Y + L +GCRC+ELDCWDG DG+P IYHGHT TTKI F V+ I Sbjct: 856 TGHQLKGESSVQLYSQVLLTGCRCVELDCWDGDDGSPLIYHGHTFTTKIPFRSVVEAIDR 915 Query: 389 HAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL---VHPMDKNETSLPSP 441 AF++S YP+ILSIE++CS QQ RMA FQ VFG+ L+ + D ++ LPSP Sbjct: 916 SAFVSSPYPVILSIENHCSQSQQARMAQIFQSVFGEKLVTKFLFDSDFDDPQLPSP 971 Score = 154 bits (374), Expect = 1e-35 Identities = 91/237 (38%), Positives = 133/237 (56%), Gaps = 14/237 (5%) Query: 964 EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023 + SS E+ A+++ +Q + + TQL R YP G RIDSSN+NPV FW G QMVAL Sbjct: 1192 QTSSLNESAAKKICRKQP-LGVLGHAETQLIRTYPAGMRIDSSNFNPVIFWAFGIQMVAL 1250 Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE------GYNPCDKKSIEGKVKPVTVM 1077 NYQT D + +N F+QNG CG++ KP M+++ +NP DK+ +G + + Sbjct: 1251 NYQTDDAALHLNAAMFEQNGQCGYVRKPSVMWDKKHMMYRRFNPWDKE-FDG-LHSAHLT 1308 Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137 L +I +++ + +S +VE+E++G D K TK + N LNP+WND F+V Sbjct: 1309 LSIISGQYVSPSNL-LSSTYVEIELVGIPIDC-AKHKTKVIQGNSLNPIWNDKFCFQVMF 1366 Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194 +LA +RF + D + I Q PL CLR GYR V L + L LSTL ++ Sbjct: 1367 KDLAFLRFGIMDA---SSHHPIAQRVLPLKCLRPGYRHVRLRTMKNRALALSTLFIY 1420 >UniRef50_Q4RKI8 Cluster: Chromosome 21 SCAF15029, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 21 SCAF15029, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 955 Score = 193 bits (471), Expect = 2e-47 Identities = 111/272 (40%), Positives = 160/272 (58%), Gaps = 9/272 (3%) Query: 932 WRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 +++ KE+SDL+ CRSV F K E+ SF ET A RL ++ F V ++ Sbjct: 555 FQLLKELSDLVTLCRSVRFVDFPTSSKSQKSWELCSFHETLALRLATESPRDF-VNHNKH 613 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 LSR+YP RIDSSN NP W CG Q+V++N+QT M +N F+QNG CG++L+P Sbjct: 614 FLSRVYPCPMRIDSSNMNPQDLWKCGCQIVSMNFQTAGLMMDLNTAWFRQNGNCGYVLRP 673 Query: 1052 QFMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCK-TGRG----TASPFVEVEIIGA 1105 M +E Y D + V P + ++VI ++L K G G P+V VEI G Sbjct: 674 AIMRQEVSYFSADTRDTVPGVSPQLLHVKVISGQNLPKPRGSGAKGDVVDPYVYVEIHGI 733 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 D ++ T+TV+ NG NP++++ EF++ PELA++RFVV D+D G+ FIGQ T P Sbjct: 734 PADC-MERRTRTVTQNGDNPIFDESFEFQINLPELAMVRFVVLDDDYIGD-EFIGQYTIP 791 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L C++ GYR VPL + EEL + L VH+++ Sbjct: 792 LECIQPGYRHVPLQSLTGEELLHARLFVHVAL 823 Score = 188 bits (458), Expect = 8e-46 Identities = 140/511 (27%), Positives = 237/511 (46%), Gaps = 47/511 (9%) Query: 2 KSVCFNGA--KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRIN 59 K+V F+ + + ++ AD + S +E GS + K R +R + + W Sbjct: 12 KTVSFSSSLSEKKISSAADCIYSMVE-GSELKKIRTNSRVYQRYYLLDTGLQALCWE--- 67 Query: 60 APQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119 +++ + + + ++EVRTG++++ F R +++ F+I YG ++ V Sbjct: 68 PSKKESDKARISLDSIREVRTGRNTETF-RTSGVYEQISEDCAFSIIYGELYE--SLDLV 124 Query: 120 AQTDKECEAWVKGVLYLIAEAVSASYPLQIER------WLRKEFYSI------ENSHEKI 167 A + + WV G+ YL+ A L + WL + F + +N E I Sbjct: 125 ANSAEVANIWVTGLRYLMQYGKHALDMLASSQDSLRLVWLEQLFSAAVDPNGKDNGEESI 184 Query: 168 TLKEVKAFLPKINCKISTSKLRDVFQDVDT--EKRGEIGFDDFA---------------- 209 +L+ + N +S SK+ F+++ ++ + D+ + Sbjct: 185 SLQSAVRLIKSANPGVSGSKVEQRFKELQRVRDRMCSLALDNGSEAKELKENKRLPMGKR 244 Query: 210 --VLYQKLI---FDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS 264 V+ Q+ I D +I+ + SN + ++ FL EQ L +E Sbjct: 245 EQVIKQEFIEVFLDFCTRPEIYFLLVQFSSNKEFLDTKDLMRFLEAEQGMALVSEETSL- 303 Query: 265 QFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSH 324 Q I+ + + + Y +L F L S + ++D ++D V QDM++PLSHY+I SSH Sbjct: 304 QLIQAH-EPSEEGRQQGYLSLDGFTSYLTSAECHLFDREHDAVCQDMSQPLSHYYICSSH 362 Query: 325 NTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLR 384 NTYL DQ S + Y+R L+ GCRC+E+D WDG DG P + GHTL+ + VL Sbjct: 363 NTYLIEDQIRGPSDISGYIRALKMGCRCVEVDVWDGSDGEPVVCTGHTLSPPLALHSVLE 422 Query: 385 TIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDX 444 I++ AF+ S+YPLI+ IE++CS QQ+ M +FGD L P ++ ++ LPSPH Sbjct: 423 AIEKCAFVASDYPLIVCIENHCSYQQQQVMCQHLTRIFGDKLYTDPPNQEDSYLPSPHAL 482 Query: 445 XXXXXXXXXXXPEGAEESSFAVRQE-EGKDL 474 G E V +E EG ++ Sbjct: 483 RHRIILKGKKLGPGLEAEDGEVSEEDEGAEM 513 >UniRef50_A0BLC4 Cluster: Chromosome undetermined scaffold_114, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_114, whole genome shotgun sequence - Paramecium tetraurelia Length = 825 Score = 192 bits (469), Expect = 4e-47 Identities = 107/270 (39%), Positives = 159/270 (58%), Gaps = 19/270 (7%) Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224 E+ITLK++K LP+++ I+ +L+ +F D E++G I D+ L ++L+ +++ V+ Sbjct: 154 EQITLKQIKGMLPQLS--ITKQELKTLFNQFDLERKGYISNSDYQDLLKRLM-NQDFVRF 210 Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFT 284 +FD+Y++ N +EF FL EQ + Q R + + F+ Sbjct: 211 LFDRYAIQQMNK-----QEFIKFLTSEQSPY----QKQCEDAFRLFAKQDGNS-----FS 256 Query: 285 LS--EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342 LS EF+ L S N ++D Q +V Q PL+ YWI+SSHNTYL GDQ +SESS++AY Sbjct: 257 LSFLEFLNYLLSTYNQLFDYQKTQVYQSEDFPLTDYWINSSHNTYLMGDQLTSESSIQAY 316 Query: 343 VRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402 + + GCRC+ELDCWDG + P IYHG T+T+KI F V+ TIKE+ F S+YPLILS+ Sbjct: 317 INAFQKGCRCVELDCWDGDNNQPIIYHGFTMTSKISFESVIETIKEYGFKYSKYPLILSL 376 Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432 E +C + QQ M + LL+ P D Sbjct: 377 EVHCCVKQQDVMTDILKTYLNVNLLLLPDD 406 Score = 144 bits (348), Expect = 2e-32 Identities = 83/218 (38%), Positives = 123/218 (56%), Gaps = 11/218 (5%) Query: 982 NTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ 1041 N + YH +RIYP G R+DSSNY+P+P +N GSQ+VALN+QT D PM +NM KF + Sbjct: 612 NENLLDYHRKYFTRIYPSGSRVDSSNYDPIPAFNSGSQIVALNFQTNDMPMLINMCKFME 671 Query: 1042 NGG--CGFILKPQFMFEEGYNPCDK-KSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFV 1098 NGG G++LKPQ+M +G ++ SI+ T+ + V L +P + Sbjct: 672 NGGIESGYVLKPQWMRSDGKKKINEFTSIQ---LSFTLSILVGYNLRLLNDQNAKVNPSI 728 Query: 1099 EVEIIGADYD-SGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157 ++ I G D K T+S NGLNP +N I ++ + P+LA + F V D + Sbjct: 729 KISIRGLLQDEQNNKPQIATISQNGLNPQFNFIYKYNIRCPDLAFLIFEVLD----ASKS 784 Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 F+G + PL C+ GYR+V L + + + L S L+VH+ Sbjct: 785 FLGWSAIPLSCMSYGYRAVQLLSQYLKPLPKSCLLVHV 822 >UniRef50_Q5CR08 Cluster: Phospholipase C, delta 1 ortholog with 2 EF hands plus phospholipase C domain plus C2 domain; n=2; Cryptosporidium|Rep: Phospholipase C, delta 1 ortholog with 2 EF hands plus phospholipase C domain plus C2 domain - Cryptosporidium parvum Iowa II Length = 883 Score = 192 bits (468), Expect = 5e-47 Identities = 116/334 (34%), Positives = 179/334 (53%), Gaps = 13/334 (3%) Query: 156 EFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFA-VLYQK 214 E ++NS I+ E+ ++ +S +F + D + G + + +F +L Q Sbjct: 220 ELSDLDNSGS-ISFTELMRLTKRLQMPVSKDYTHALFCEYDNDNNGALDYKEFRNLLTQL 278 Query: 215 LIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDP 274 LI E ++D+FD+Y +N + +F+NFL D Q D + L Sbjct: 279 LILPE--LRDLFDEYKDPDTN--VMGANKFRNFLIDVQGM---DPSNSLESLVNAVLNMK 331 Query: 275 QRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334 + I T F ++ S+ NS +D V Q M P+SHYWI+SSHNTYLTGDQ + Sbjct: 332 EPFIERGGITEIGFNILMSSEFNSAFDPLKRDVYQSMDEPISHYWIASSHNTYLTGDQLT 391 Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITS 394 S+S + Y+ L GCRC+ELD W+GPDG+P IYHGHTLT+K+ F DV+R K++AF S Sbjct: 392 SKSEIGQYITVLLQGCRCVELDVWNGPDGSPIIYHGHTLTSKVYFEDVIRACKDYAFQIS 451 Query: 395 EYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXX 454 YP+ILS+E + S Q+ ++A +V GD L + P D ++ LP+P++ Sbjct: 452 PYPIILSLEMHASDKQREKVAEIILNVLGDSLYIPPNDGSD-RLPTPNE-LKYKFLVKAK 509 Query: 455 XPEGAEESSFAVRQEEGKDLDLRNSIKNGILHLE 488 P+ E+ SF +R + D +N + IL ++ Sbjct: 510 VPK--EDISFDLRAGVINEDDEKNDLNPDILEVD 541 Score = 133 bits (322), Expect = 2e-29 Identities = 82/260 (31%), Positives = 138/260 (53%), Gaps = 27/260 (10%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 + S ETK RL ++ + K+H L R+YP G RI SSNYNP+ W+ G+Q+VALN Sbjct: 593 IGSLVETKFLRL-AKDSSMSLAKFHQDHLCRVYPSGTRISSSNYNPLIPWSYGAQIVALN 651 Query: 1025 YQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEGY--------NPCDKKSIEGKVKPV 1074 YQ + +N G+F+QNGG G++LKP+ ++ + NP + + + PV Sbjct: 652 YQAVGTALLLNEGRFRQNGGSKSGYVLKPKMCLKKCFDGRVFDPMNPLETLEL-FDIPPV 710 Query: 1075 TVMLRVIGAR----HLCKTGRGTA--------SPFVEVEIIGADYDSGVKLVTKTVSDNG 1122 V ++++ A +L + RG A SP++ + + G + T +++NG Sbjct: 711 RVCIQILSAHQLPDNLSQFSRGIAGLISGNKLSPYITISVFGGPSEEFKSYRTPVINNNG 770 Query: 1123 LNPLWNDIC--EFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180 NP W ++ F V PE+++I F V+ D + FI A+ P+ CLR G R + L + Sbjct: 771 FNPKWENLSPFTFNVLCPEISIINFEVKSSDSI-QSEFIAAASIPVSCLRPGLRWIQLFD 829 Query: 1181 AFSEELELSTLMVHLSIITD 1200 A +++ ++ ++SI T+ Sbjct: 830 ANFIDIQCCGILANISITTE 849 >UniRef50_Q4RSB2 Cluster: Chromosome 13 SCAF15000, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13 SCAF15000, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 551 Score = 192 bits (467), Expect = 6e-47 Identities = 110/269 (40%), Positives = 155/269 (57%), Gaps = 6/269 (2%) Query: 927 KMERTWRIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 +M + +I K +SDL++Y RSV F + R Y E +S E KA +L+ + F Sbjct: 282 RMTGSKKIVKALSDLVVYTRSVKFCSFTHSRDNQHSY-ENTSLEENKARKLL-KSSGADF 339 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 V ++ LSRIYP G R SSNYNP FWN G Q+VALN+Q+ PM +N G+F+ NGGC Sbjct: 340 VGHNQRFLSRIYPAGSRTSSSNYNPQEFWNVGCQLVALNFQSLAAPMDLNDGRFQDNGGC 399 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-CKTGRGTASPFVEVEIIG 1104 G++LKP + D + + +V+PV ++L+VI +L R + PFV+VEI G Sbjct: 400 GYVLKPVVLM-SSQGCFDPRRSQRRVRPVHLLLKVISGSNLPILKSRKSLDPFVKVEIHG 458 Query: 1105 ADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATF 1164 DS K T TV +N L+P W+ F+++ PEL LIRF V+D+ F+GQ T Sbjct: 459 IPSDSS-KQSTHTVKNNSLSPHWDAHMNFKISTPELCLIRFCVRDQTGLLSSEFVGQYTL 517 Query: 1165 PLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 P L KGYR VPL + L+ ++L V Sbjct: 518 PFTSLMKGYRWVPLWSRDGCSLDPASLFV 546 Score = 185 bits (450), Expect = 7e-45 Identities = 98/221 (44%), Positives = 132/221 (59%), Gaps = 4/221 (1%) Query: 224 DIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYF 283 DI Y Y S+ T ++ FL EQ + L DE + I+ Y + I Sbjct: 14 DIQQLYQRYLSDAT-LSAANLLQFLHKEQKE-LTADEDTTKRLIQRYEIEHSA-IEAKSM 70 Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 T F + SK+ +++ + V QDM +PLS Y+ISSSHNTYLTGDQ +S L+AYV Sbjct: 71 TFEGFFRYMESKECCVFNQAHTSVYQDMDQPLSSYFISSSHNTYLTGDQLVGKSHLDAYV 130 Query: 344 RCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIE 403 LR GCRC+E+DCWDG D P +YHG+TLTTKI F +V+ T+++HAF S YP+ILS+E Sbjct: 131 CALRKGCRCLEIDCWDGADMEPVVYHGYTLTTKILFKEVITTVEQHAFEKSPYPVILSLE 190 Query: 404 DNCSLPQQRRMASAFQDVFGDLLLVHPMDKNET-SLPSPHD 443 ++C QQ MA + G+ LL P+D T LPSP+D Sbjct: 191 NHCCKEQQEIMAHYLVSILGEKLLRAPIDHPATGELPSPND 231 >UniRef50_UPI000023F2A0 Cluster: hypothetical protein FG05898.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG05898.1 - Gibberella zeae PH-1 Length = 1111 Score = 189 bits (460), Expect = 5e-46 Identities = 129/442 (29%), Positives = 219/442 (49%), Gaps = 34/442 (7%) Query: 24 IERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKS 83 + G V K + RP+R L E++++ W + PQ+ +L + +++E+RTG Sbjct: 231 LRNGCPVKKVSKKSRPKRITLAYETESNKLSWDP-SRPQK-----SLHVDEIREIRTGTD 284 Query: 84 SKDFERWPEETKRLES--SKCFTIYYGT--EFKLRCASFVAQTDKECEAWVKGV------ 133 + + ++++E FTI Y K R V W + + Sbjct: 285 IQQYIHDYGLSEQIEFYFPVWFTIIYNVPESSKTRFLHIVTDNSNTLSLWTEFLDAMLRY 344 Query: 134 -LYLIAEAVSASYPLQIERW---LRKEFYSIENS--HEKITLKEVKAFLPKINCKISTSK 187 L+ +S + + W + KEF + E++ + VK ++ S+S Sbjct: 345 RQQLMTSLMSFNDRAVAQYWQTEMAKEFGDQARTPDQEEMNIAGVKRVCQNLHIYSSSST 404 Query: 188 LRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNF 247 L F D+ +R ++ F +F +++ N+VQ + + G +TL EF F Sbjct: 405 LEVNFHLSDSRRRSKLNFREFKDFVRRMK-QRNDVQRVIRNIAANPEFG--LTLSEFLTF 461 Query: 248 LRDEQHDNLGDD----EVQASQFIRDYLRDPQRDIYEPYFTLSE--FVEMLYSKQNSIYD 301 LRD+Q +++ + E S+F R Y R + D+ E ++E FV L S+ N + Sbjct: 462 LRDDQGEDVDSNRTAWEKLFSRFCRQY-RSTEADLPENVEIMTEAAFVAFLTSEDNEVIQ 520 Query: 302 SQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGP 361 + + D RP++ Y+ISSSHNTYL G Q + +SS+E Y+ L GCRC+E+DCWDG Sbjct: 521 PEPQNIVLD--RPMNEYYISSSHNTYLLGRQVAGQSSVEGYISALARGCRCVEVDCWDGY 578 Query: 362 DGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDV 421 +G P + HG T+TT I F +V+ TI ++AF+ S++PL +S+E +CS QQ M ++ Sbjct: 579 NGQPEVNHGRTMTTSISFKEVMTTINKYAFVKSKFPLWISLEVHCSPAQQATMVEIIKES 638 Query: 422 FGDLLLVHPMDKNETSLPSPHD 443 FG L+ ++ LP+P + Sbjct: 639 FGSRLVTETLEAFPDKLPTPSE 660 Score = 111 bits (268), Expect = 8e-23 Identities = 82/293 (27%), Positives = 143/293 (48%), Gaps = 30/293 (10%) Query: 933 RIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 + K + DL +YC V F+ + + K YN + SF E+ + ++ + H Sbjct: 769 KTVKVLGDLGVYCAGVKFSGFDTVDAKQ--YNHIFSFMESSFAKHSRAKDQKMALDIHNM 826 Query: 992 Q-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050 + + R+YP RI S+N++P+ +W G QM ALN+QT D MQ+N F G++LK Sbjct: 827 RYMMRVYPDRTRITSNNFDPLNYWRRGVQMAALNWQTFDLGMQLNRAMFDGKDSSGYVLK 886 Query: 1051 PQFMFEEGYNPCDKKSIEGKVK--PVTVMLRVIGARHLCKTGRGTAS----PFVEVEIIG 1104 P + + P + EGK + ++ + VI A+ L + A+ P+VEVE+ Sbjct: 887 PAELRDIQVLPYNADIAEGKKERTVISFTIDVISAQQLMRPANLPANKSMDPYVEVEVFH 946 Query: 1105 A---------------DYDSGVKLVTKTVSDNGLNPLWNDICEFEVA--NPELALIRFVV 1147 A ++D+ +K T + +NG NPL++ ++ V +P+L +R+ V Sbjct: 947 ANDKRDKKEADSNLVLEHDTPLKYQTDVIRENGFNPLFDRTMKYTVTTKHPDLIFVRWSV 1006 Query: 1148 Q---DEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 + D + + E + T L L++GYR++PL N ++ S L + I Sbjct: 1007 KLSNDGESYNERPAVATYTAKLTNLKQGYRTLPLLNHAGDQYLFSKLFCKIKI 1059 >UniRef50_A7RKT2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 433 Score = 188 bits (459), Expect = 6e-46 Identities = 110/242 (45%), Positives = 143/242 (59%), Gaps = 16/242 (6%) Query: 215 LIFDENNVQD-IFDKYSVYCSNGTTITL--REFQNFLRDEQHDNLGDDEVQASQFIRDYL 271 ++FD N Q + Y+ Y + + L EFQ FL EQ ++L + D L Sbjct: 162 MLFDSLNEQARLLSVYATYARSYPHLGLSPEEFQAFLAKEQKESLSLAMCAKLIYAHDKL 221 Query: 272 R----------DPQRDIYEPYF-TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWI 320 DP +F +L F+ L S+ NSI +++KV QDM +PLS Y+I Sbjct: 222 HTMFKRKCAGNDPDAFKRSKHFLSLHGFISFLRSQDNSIVKPEHNKVYQDMDQPLSDYFI 281 Query: 321 SSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFM 380 +SSHNTYLTG Q SSLEAYVR L GCRCIELD WDGPD P I HG TLT+KIRF Sbjct: 282 NSSHNTYLTGHQLKGLSSLEAYVRALLQGCRCIELDIWDGPD-EPIITHGRTLTSKIRFR 340 Query: 381 DVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440 DV++ IKE+AF SEYPLILS+E++C++ QQ +MA F FGD+L+ + LPS Sbjct: 341 DVVQIIKEYAFEVSEYPLILSLENHCNIQQQAQMAEIFLKDFGDMLVTQDFCRGNV-LPS 399 Query: 441 PH 442 P+ Sbjct: 400 PN 401 >UniRef50_UPI0000E49F73 Cluster: PREDICTED: similar to KIAA1092 protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to KIAA1092 protein - Strongylocentrotus purpuratus Length = 684 Score = 188 bits (457), Expect = 1e-45 Identities = 95/201 (47%), Positives = 119/201 (59%), Gaps = 1/201 (0%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 Y + F L S + I+D Q +V QDMT+ LSHY+I++SHNTYLT DQ SS+ A Sbjct: 59 YLGIDGFTSYLLSSECDIFDHQQRRVCQDMTQSLSHYFIAASHNTYLTEDQLKGPSSVAA 118 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401 YV L+ GCR +ELD WDG + P IYHGHTLT+KI F + I +HAF TSEYP+I+S Sbjct: 119 YVSALQKGCRWVELDVWDGANDEPIIYHGHTLTSKILFKAAIEAINQHAFETSEYPVIVS 178 Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEE 461 IE++CS QQR MA VFGD L +D++ + LPSPHD P+ E Sbjct: 179 IENHCSPEQQRTMAHYITSVFGDKLHTDRIDEDLSYLPSPHDLQGKILIKGKRLPDDHEG 238 Query: 462 SSFAVRQE-EGKDLDLRNSIK 481 V E EG D D IK Sbjct: 239 DEGEVTDEDEGSDTDRGKKIK 259 Score = 92.3 bits (219), Expect = 7e-17 Identities = 56/145 (38%), Positives = 84/145 (57%), Gaps = 10/145 (6%) Query: 1060 NPCDKKSIEGK-VKPVTVMLRVIGARHLCKTGRGTAS------PFVEVEIIGADYDSGVK 1112 NP D ++ + V P + +++I + K RG+ S P++ VEI G D + Sbjct: 342 NPQDMWNVGCQIVSPQILHIKIISGQQFPKP-RGSGSKGEVIDPYISVEIFGIPADCKEE 400 Query: 1113 LVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172 TKTV NG NP++++ EF V PELAL+RFVV D+D G+ FIGQ T P CL+ G Sbjct: 401 R-TKTVPHNGYNPIFDESFEFSVNLPELALVRFVVLDDDFIGD-EFIGQYTIPFECLQPG 458 Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197 YR + L + E L+ ++L VH+++ Sbjct: 459 YRHITLLSNTGEPLKPASLFVHVAV 483 Score = 62.9 bits (146), Expect = 5e-08 Identities = 42/140 (30%), Positives = 63/140 (45%), Gaps = 1/140 (0%) Query: 934 IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQL 993 + +E+SDL+ C+SV F + Y E+ SF E AE+ + + V ++ L Sbjct: 268 LIRELSDLVTLCKSVRFLGFNEARQDQRYWEICSFVENTAEKFANMCPEDY-VSHNKRYL 326 Query: 994 SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053 SR+YP R+DS+N NP WN G Q+V+ K + +G G ++ P Sbjct: 327 SRVYPNPNRVDSTNLNPQDMWNVGCQIVSPQILHIKIISGQQFPKPRGSGSKGEVIDPYI 386 Query: 1054 MFEEGYNPCDKKSIEGKVKP 1073 E P D K K P Sbjct: 387 SVEIFGIPADCKEERTKTVP 406 >UniRef50_UPI00006CFB88 Cluster: Phosphatidylinositol-specific phospholipase C, X domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Phosphatidylinositol-specific phospholipase C, X domain containing protein - Tetrahymena thermophila SB210 Length = 989 Score = 188 bits (457), Expect = 1e-45 Identities = 96/285 (33%), Positives = 172/285 (60%), Gaps = 17/285 (5%) Query: 161 ENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDEN 220 ++ ++++ L+EVK L +++ ++ L+ +FQ D + +I +F + + I ++ Sbjct: 155 KDGNKQLDLEEVKKLLQELHVSVNKKYLKQLFQTYDYNQNNQIDQGEFINIIRD-ISKKD 213 Query: 221 NVQDIFDKY------SVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDP 274 + IF +Y V +T+ E+Q FL+++Q N+ E+ + R+ + + Sbjct: 214 ELLTIFKQYCQSYNQQVSLDQEGLMTIEEYQLFLQEQQKQNVPIHELL--ELFRN-INNV 270 Query: 275 QRDIYEPYFTLSE-------FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTY 327 Q ++ E T + F ++++++NS+ D ++ +V Q+M PLS Y+I+SSHNTY Sbjct: 271 QINVIESAKTSKDLKISFYQFSNLIFTQENSVLDIKHQEVHQNMNLPLSDYFINSSHNTY 330 Query: 328 LTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIK 387 L +Q + +SS +AY+ GCRC+ELDCWDG + P +YHGHTLT++I F DVL+TI+ Sbjct: 331 LMANQLTGDSSCQAYINAFLRGCRCVELDCWDGENNEPLVYHGHTLTSRILFKDVLQTIE 390 Query: 388 EHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432 ++AF+TS +P+ILS E++CS+ Q +++A + +F D L P D Sbjct: 391 KYAFMTSPFPVILSFENHCSVEQSKKIAYYLKTIFKDKLFTVPKD 435 Score = 134 bits (325), Expect = 1e-29 Identities = 80/230 (34%), Positives = 123/230 (53%), Gaps = 10/230 (4%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 +SS E K +L+ + + + + R+YP G R+DSSNY+P+ + G+Q+VALN Sbjct: 740 ISSISEVKYLKLIKKCPGVLIQMFKKSFI-RLYPGGMRVDSSNYDPIKGFLSGAQIVALN 798 Query: 1025 YQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVML---R 1079 +QTPD PM N+ KF++NGG G++LKP +M + VK V + + + Sbjct: 799 FQTPDLPMVFNLSKFQENGGIHSGYVLKPNYMLHHSKKDYIPTLMTKTVKVVRIQIISGQ 858 Query: 1080 VIGARHLCKTGRGTASPFVEVEIIGADYD--SGVKLVTKTVSDNGLNPLWND-ICEFEVA 1136 + + P+V+V + G D+D + VT V DNG +P+WN + EF A Sbjct: 859 QLRPEDYEQDTFDVVDPYVQVFVKGTDFDENNNKPCVTDVVYDNGFHPIWNSHVFEFRFA 918 Query: 1137 NPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEEL 1186 PELA+I F V D D+ G +G + C+R GYR +PL + + EL Sbjct: 919 CPELAMIVFRVMDSDV-GIDTQLGIYAISVDCMRPGYRMIPLRSKSNLEL 967 >UniRef50_Q4T850 Cluster: Chromosome 16 SCAF7896, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 16 SCAF7896, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1045 Score = 185 bits (451), Expect = 6e-45 Identities = 93/252 (36%), Positives = 152/252 (60%), Gaps = 8/252 (3%) Query: 193 QDVDTE-KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDE 251 ++ DT+ ++G + +++F+V Y+ + +D+F Y +T E NFL +E Sbjct: 2 EEADTDDQQGTLTYEEFSVFYKMMSLR----RDLFLLMMAYSDRKDHLTAEELANFLHNE 57 Query: 252 QHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDM 311 Q E A + + D + + + F + S I++ +++V QDM Sbjct: 58 QKMTNVTPEYVAEIIQKFEVADENKQ--KGVMGIEGFTNFMRSPACDIFNPLHNEVNQDM 115 Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGH 371 +PL +Y+I+SSHNTYLTGDQ S S + Y L+SGCRC+E+DCWDGPDG P + HG+ Sbjct: 116 EQPLCNYFIASSHNTYLTGDQLLSHSKTDMYAWVLQSGCRCVEVDCWDGPDGEPMVQHGY 175 Query: 372 TLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV-HP 430 TLT+KI F V+ TI ++AFI +++P+ILSIE++C++ QQ+++A +++FGD L V Sbjct: 176 TLTSKIPFRFVIETINKYAFINNQFPVILSIENHCTIQQQKKIAQYLREIFGDKLDVGDV 235 Query: 431 MDKNETSLPSPH 442 + + +LPSP+ Sbjct: 236 LSGDSKTLPSPN 247 Score = 172 bits (418), Expect = 6e-41 Identities = 106/278 (38%), Positives = 157/278 (56%), Gaps = 19/278 (6%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + +T ++++++S+L+++ SV E L +G ++ SF ET+A+ L++ + F Sbjct: 430 RKRKTMKLSRDLSNLVVFTNSVASQ-ECLN-EG-TPADVLSFSETRAQSLVNHRAEQFLA 486 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 ++ QLSRIYP RIDSSN+NP +WN G Q+VALNYQT + MQ+N KF NGG G Sbjct: 487 -FNQRQLSRIYPSAYRIDSSNFNPQFYWNVGCQLVALNYQTEGRMMQLNRAKFMVNGGIG 545 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASPFVE 1099 ++LKP M + +NP + K ++L++I + L K RG PFVE Sbjct: 546 YVLKPPPMCKGSFNPFSDDPLPACPKK-QLILKIISGQQLPKPPDSMLGDRGEIIDPFVE 604 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFI 1159 VEIIG D K T+ V DNG NP+W + F + E+ L+RF+V D D G +FI Sbjct: 605 VEIIGLPVDC-CKEQTRVVDDNGFNPVWEETLSFTLHMAEVVLVRFLVWDHDPIGR-DFI 662 Query: 1160 GQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 GQ T L GYR V + E L +++ VH+S+ Sbjct: 663 GQRTVAFNSLMPGYRHV-----YLEGLTEASIFVHVSV 695 >UniRef50_UPI000069FB24 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4); n=1; Xenopus tropicalis|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta 2 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C-eta- 2) (PLC-eta-2) (Phosphoinositide phospholipase C-like 4) (Phospholipase C-like 4) - Xenopus tropicalis Length = 574 Score = 184 bits (449), Expect = 1e-44 Identities = 104/256 (40%), Positives = 151/256 (58%), Gaps = 18/256 (7%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 + ++T ++++ +SDL+ Y +SV + ++SSF ETKA +++ QQ+ FV Sbjct: 320 RQKKTMKLSRALSDLVKYTKSVGIHDVETESNW----QVSSFSETKAHQIL-QQKPAQFV 374 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ QLSRIYP R+DSSNYNP PFWN G Q VALNYQ+ + +Q+N KF NG CG Sbjct: 375 RFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQSVALNYQSEGRMLQLNRAKFNSNGNCG 434 Query: 1047 FILKPQFMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKT------GRG-TASP 1096 ++LKP+ M + +NP + + G++K ++LR+I + L K RG P Sbjct: 435 YVLKPKCMCQVIVGAFNPNSEDPLPGQLKK-QLVLRIISGQQLPKPKDSMLGDRGEIIDP 493 Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156 FVEVE+IG D K T+ V DNG NP+W + F V PE++LIRF+V D D G Sbjct: 494 FVEVELIGLPVDC-FKEQTRVVDDNGFNPMWEETLVFTVHMPEISLIRFLVWDHDPIGR- 551 Query: 1157 NFIGQATFPLLCLRKG 1172 +FIGQ T + G Sbjct: 552 DFIGQRTLSFSSMMPG 567 Score = 182 bits (442), Expect = 7e-44 Identities = 90/243 (37%), Positives = 148/243 (60%), Gaps = 7/243 (2%) Query: 200 RGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDD 259 +G +GFD+F Y+ + + +D++ Y ++ + + + FL EQ + Sbjct: 1 QGTLGFDEFCAFYKMM----STRRDLYLLMLTYSNHKDHLDPDDLKRFLEVEQK-MINVT 55 Query: 260 EVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYW 319 + + + P+ + + F + S I++ + +V QDMT PLS+Y+ Sbjct: 56 KEYCLDIVDKFEPCPENK-KQGALGIDGFTNYMRSPAGDIFNPDHYQVNQDMTLPLSNYF 114 Query: 320 ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRF 379 I+SSHNTYL GDQ S+S ++ Y L++GCRC+E+DCWDGPDG P ++HG+TLT+KI F Sbjct: 115 IASSHNTYLMGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILF 174 Query: 380 MDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-LVHPMDKNETSL 438 DV+ TI ++AFI ++YP+ILSIE++CS+ QQ++MA ++ G+ L L ++++ T L Sbjct: 175 KDVIETINKYAFIRNDYPVILSIENHCSVVQQKKMAQYLIEILGEKLNLSDVVNEDSTKL 234 Query: 439 PSP 441 PSP Sbjct: 235 PSP 237 >UniRef50_UPI0000E817B6 Cluster: PREDICTED: hypothetical protein; n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein - Gallus gallus Length = 729 Score = 183 bits (446), Expect = 2e-44 Identities = 143/455 (31%), Positives = 215/455 (47%), Gaps = 31/455 (6%) Query: 2 KSVCFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 K+V F+ DR I+ A IS++ G + K R R + + V W Sbjct: 21 KTVSFSTMPNDRKINSAAACISFMLEGCELKKVRSNSRMYSRFFVLDADMRSVRWE---- 76 Query: 61 PQRQGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFV 119 P ++ E A ++I+ VKEVR GK + R + + F+I YG ++ V Sbjct: 77 PSKKDSEKAKIEIKSVKEVRVGKKTPIL-RSNGLSDQFPDECAFSIIYGDNYE--SLDLV 133 Query: 120 AQTDKECEAWVKGVLYLIA------EAVSASYPLQIERWLRKEF--YSIENS-HEKIT-- 168 A + AWV G+ YL++ EA+ + +P W+ F +E S H ++ Sbjct: 134 ASSADVVSAWVMGLRYLLSYGKHTPEALGSGHPSLRTSWISSVFDLADLEKSGHIPVSRA 193 Query: 169 LKEVKAFLPKINCKISTSKLRDVFQDVDTEKRG-EIGFDDFAVLYQKLIFDENNVQDIFD 227 ++ +KA P + K+ST +L+ +E+ G E+ D F Y +L +IF Sbjct: 194 VQLIKALNPGM--KVSTIELKFKELQKASERPGTEVACDLFVEAYCELC----TRPEIFF 247 Query: 228 KYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLS 286 + SN + L++ FL EQ G E + + I Y +P ++ E Y + Sbjct: 248 LLVQFSSNKEYLGLKDLLTFLEVEQGME-GITEEKCLEIISKY--EPSKEGREKGYLAID 304 Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346 F L S SI+D Q+ +V QDM +PLSHY+ISS+H+ L D F S + YV L Sbjct: 305 GFTRYLLSSDCSIFDPQHRRVCQDMAQPLSHYYISSAHSACLLEDNFWGRSDISGYVSAL 364 Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406 GCR IEL WDGP+G P +Y + + + F V+ I +HAF S YPLIL + C Sbjct: 365 GLGCRSIELVLWDGPEGEPVVYTSPSAASCVPFRSVVGLIDQHAFAASAYPLILCLVVRC 424 Query: 407 SLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 S QQR A + G+ L + P D + LPSP Sbjct: 425 SAAQQRLAAQCLRKTLGEKLYLEPPDPARSYLPSP 459 >UniRef50_A7SXK4 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 553 Score = 182 bits (443), Expect = 5e-44 Identities = 89/230 (38%), Positives = 137/230 (59%), Gaps = 6/230 (2%) Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271 + K I V +F S SNG +T+ + ++F+ +Q ++ + I+ + Sbjct: 1 FYKFISKRKEVDLLFRNVS---SNGAWVTVDDLEDFMTKDQRFDV--THKTCKELIKKF- 54 Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331 QR + + F+ + S+ S+++ ++K+ QDM +PLSHY+I+SSHNTYL G Sbjct: 55 EVSQRGKAQLQLGIDGFLSFINSQHASLFNPAHEKIYQDMNQPLSHYFIASSHNTYLLGH 114 Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAF 391 Q SS++AY L GCRC+ELDCWDG D P +YHGHTLT+K+ F D+++ IKE AF Sbjct: 115 QLKGSSSVQAYRDVLERGCRCVELDCWDGDDEEPIVYHGHTLTSKVLFKDIVQAIKESAF 174 Query: 392 ITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 S YP+I+S+E++CS+ Q +MA + + G LL P+D +LPSP Sbjct: 175 KVSPYPVIVSLENHCSVQFQIKMAEHLKGILGSLLYTTPVDFTLDALPSP 224 Score = 163 bits (397), Expect = 2e-38 Identities = 99/274 (36%), Positives = 154/274 (56%), Gaps = 15/274 (5%) Query: 934 IAKEISDLIIYCRSVTFN--IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 +A E+S LI Y + F IE + + F ++ SF E++ + + + F V+++ Sbjct: 276 VADELSQLINYISNEKFKSFIESMEMGHF--SQTHSFVESEMLYFLDKSASEF-VEFNKH 332 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 Q+SRIYP R+DSSNY+P+ W G Q+VALN+QT + MQ++ GKF+QNG G++LKP Sbjct: 333 QISRIYPGNLRVDSSNYDPIKPWTVGCQIVALNHQTNSEEMQLHYGKFRQNGNTGYVLKP 392 Query: 1052 QFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTG------RGTASPFVEVEII 1103 +F+ E ++P + ++P + L VI A L + R P+V+VE+ Sbjct: 393 KFLRDPELTFDPDPQDGKFPGIQPKRLQLTVISAFQLLEIEESWSLVRDEPDPYVQVEVH 452 Query: 1104 GADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQAT 1163 G D T ++D LNP+WN+ + V PELA+++FVV DED +G +F+GQ Sbjct: 453 GVPADKAT-FTTHGLTDTTLNPVWNEEFQTIVHVPELAMVQFVVYDED-YGFDDFLGQVV 510 Query: 1164 FPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 P L +GYR + L + L +TL VH+ I Sbjct: 511 IPFESLMEGYRQIQLLDMSGLPLPGTTLFVHVKI 544 >UniRef50_A2QRK1 Cluster: Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4; n=11; Eurotiomycetidae|Rep: Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4 - Aspergillus niger Length = 1156 Score = 182 bits (442), Expect = 7e-44 Identities = 138/457 (30%), Positives = 216/457 (47%), Gaps = 43/457 (9%) Query: 17 ADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVK 76 A ++ + I+RG K ++R + R + + +V W N P ++ Y + D+K Sbjct: 226 APKVDAMIQRGVIFTKITKKRRKQVRFF-LDLDAGKVYWDLSN-PTKRFY-----VDDIK 278 Query: 77 EVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFK----LRCASFVAQTDKECEAWVKG 132 E+R G ++++ + ++ ES + E ++ +A +D E W Sbjct: 279 EIRVGVDARNYREEHQVSQDFESRWITVVIADAERSKGRSVKTLHLIAPSDYTLELWTTT 338 Query: 133 VLYLIAEAVSASYPL----QIE-----RWLRK--EFYSIE---NSHEKITLKEVKAFLPK 178 + ++ + L Q E W R+ Y E + + V++ Sbjct: 339 LEHISRYRIGLMAGLAGSGQSEAVLKAHWQREMTRLYPKGLKLGELESLDFEAVESVCRS 398 Query: 179 INCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238 ++ S + LR F D +G++ F +F+ +L + +V+ IF K V S G Sbjct: 399 LHINCSKNMLRAQFSKADNNNKGKLYFSEFSDFVARLK-ERKDVKAIF-KERVASSEG-- 454 Query: 239 ITLREFQNFLRDEQHDNLGDDEVQ-ASQFIR----DYLRDPQ-------RDIYEPYFTLS 286 TL EF FLRD Q++++ D S F R R P R P L Sbjct: 455 FTLEEFLAFLRDVQNEDVESDRSYWVSIFDRLVRKSRPRAPSLPEHPDGRPTGVPRLGLD 514 Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346 F L S N +Y S+ + D RPL+ Y+ISSSHNTYL G Q + SS EAY+ L Sbjct: 515 AFTSFLSSSWNGVYASRAPQSRFD--RPLNEYFISSSHNTYLLGRQVAGASSTEAYISAL 572 Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406 GCRC+E+DCWDG DG P + HG T+TT + F D + I +AFI++++PLILS+E +C Sbjct: 573 SQGCRCVEIDCWDGADGRPIVSHGRTMTTSVLFADCITVINRYAFISTDFPLILSLEVHC 632 Query: 407 SLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 + QQ M ++ F D L++ P+ N LPSP D Sbjct: 633 NPEQQLAMVRIMKETFKDQLVLEPLLTNTFVLPSPED 669 Score = 104 bits (249), Expect = 2e-20 Identities = 92/307 (29%), Positives = 141/307 (45%), Gaps = 41/307 (13%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQEN-TFF 985 K + +I K +SDL +Y R ++ + YN + SF E E + +N F Sbjct: 772 KRRQKSKITKPLSDLGVYTRGYKWH-SFTSPESQRYNHVYSFAERSFESICRDADNKAVF 830 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ-NGG 1044 K++ L+R+YP G R+ SSN++P+ FW G QM ALN+QT D MQ+N + Sbjct: 831 EKHNRKYLTRVYPSGFRLRSSNFDPLKFWRRGVQMAALNWQTYDVGMQLNQAMYAAGTDR 890 Query: 1045 CGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGR----GTASPFVEV 1100 G++LKP+ + +KS E K V + V+ A+ L + +P+VEV Sbjct: 891 TGYVLKPESLRTVTTGEDRRKSTERKC--VRFTIEVVSAQQLPRPRSLGPDDNINPYVEV 948 Query: 1101 EIIGADYDSGVKLV------------------------TKTVSDNGLNPLWNDICEF--E 1134 EI AD D G V TK NG +P++ND +F + Sbjct: 949 EIFSAD-DRGQSFVFGEGGLNTSARSGVSGIGYPHRRRTKIEQSNGYSPIFNDCFKFALD 1007 Query: 1135 VANPELALIRFVV---QDEDIFGEPNFIGQATF--PLLCLRKGYRSVPLTNAFSEELELS 1189 P+L +R+ V D G + + ATF L L +GYR +PL +A ++ S Sbjct: 1008 TKYPDLVFVRWTVWSSLDGRSAGNNSSVQLATFTAKLTSLSQGYRYLPLYDAGGDQYLFS 1067 Query: 1190 TLMVHLS 1196 TL ++ Sbjct: 1068 TLFCKIT 1074 >UniRef50_Q02158 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase; n=2; Dictyostelium discoideum|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase - Dictyostelium discoideum (Slime mold) Length = 801 Score = 182 bits (442), Expect = 7e-44 Identities = 118/418 (28%), Positives = 209/418 (50%), Gaps = 30/418 (7%) Query: 27 GSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVKEVRTGKSSKD 86 G T+LK + +P+++ L +Q++ G + ++ ++ E+R G + Sbjct: 61 GLTILKISSKGKPQKKKLIFDLARNQIVC---------GKKKKVNFSEIDEIRVGHKTNI 111 Query: 87 FERWPEETKRLES----SKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIAEAVS 142 F ++ E + F+I + + + FV E V + +++ E+ S Sbjct: 112 FNQFKSSKNLKEDIESIQQSFSILFSGNLR-KTMDFVCSDIPERRQIVSALYHVVQESKS 170 Query: 143 ASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGE 202 + ++++E+ + + I +K L ++N S + L ++ + D+ Sbjct: 171 VNNEYN---FVKREWDRV--GKDSIDFSTLKKILARLNFTTSDAVLHNLMKFSDSNSDYH 225 Query: 203 IGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ 262 + F +F+ L KL+ ++ +F KY+ NG + ++ +F R EQ EV Sbjct: 226 LDFSEFSNLL-KLLRSHPEMKPVFYKYNG--GNGEWVPIQGMIDFFRIEQ------SEVW 276 Query: 263 ASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISS 322 + RD ++ + + + F E + + N V QD ++PLS+Y+I+S Sbjct: 277 TVEQCRDLIKKYHHERLD-CISFENFEEFICGEANLAQYPHTSTVYQDTSKPLSYYFINS 335 Query: 323 SHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDV 382 SHNTYL+G Q S+ E Y LR GC+C+ELD WDG DG P I+HG+TLT++I+F V Sbjct: 336 SHNTYLSGHQLKGLSTSEMYTNTLRQGCKCVELDVWDGNDGDPIIFHGNTLTSQIKFSHV 395 Query: 383 LRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440 TIK F TS YP+ILS+E +CS+PQQ MA+ +++FG++L P+ + LP+ Sbjct: 396 CETIKARGFETSPYPVILSLEVHCSVPQQIMMANHMKEIFGEMLPT-PLPEGTKELPT 452 Score = 151 bits (365), Expect = 1e-34 Identities = 94/273 (34%), Positives = 144/273 (52%), Gaps = 13/273 (4%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +IA E +LI Y S F K ++ S E K ++L+ Q E V+ Sbjct: 534 KIAPEFEELI-YLVSHGFKSGNTT-KEIPSYKIHSLVEEKVKQLV-QSEPREVVEASQNH 590 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 L R+YP+G R DSSN++P+P W+ G Q+ ALN QT +PM +N G F NGGCG++LKP Sbjct: 591 LLRVYPRGTRFDSSNFDPMPGWSIGCQLAALNQQTSSEPMWINDGMFSDNGGCGYVLKPP 650 Query: 1053 FMFE---EGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGT----ASPFVEVEIIGA 1105 + E Y+P + I+ K +++ VI AR L K + T P+V + I+G Sbjct: 651 CLLPGECETYDPTSPERIKSS-KYSRLIVNVISARQLPKYTKSTKGEVIDPYVTLSIVGT 709 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 +D V+ TK + +NG NP W + EF + N +L+++ V D+D G N IG Sbjct: 710 HFDQKVE-KTKVIDNNGFNPHWGEEFEFPLYNSQLSMLLIRVDDKDKVGH-NRIGHHCIR 767 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 + +R GYR + L N F+ + L+ L+ + + Sbjct: 768 VENIRPGYRILKLKNNFNRTIPLANLLCKFTFV 800 >UniRef50_UPI0000DB73F3 Cluster: PREDICTED: similar to no receptor potential A CG3620-PD, isoform D; n=2; Apis mellifera|Rep: PREDICTED: similar to no receptor potential A CG3620-PD, isoform D - Apis mellifera Length = 1074 Score = 180 bits (439), Expect = 2e-43 Identities = 132/407 (32%), Positives = 206/407 (50%), Gaps = 33/407 (8%) Query: 62 QRQGYEG-ALDIRDVKEVRTGKSSKDFERWPE-ETKRLES--SKCFTIYYGTEF-KLRCA 116 Q +G +G +++ V ++R G KD + + + TK E KC TI G ++ + Sbjct: 53 QSEGRDGDVIELCQVSDIRAGGLPKDPKLYDKLVTKHGEQLEEKCLTICSGVDYTNINYQ 112 Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASY-PLQI--ERWLRKEFYSIENSHEKITLKEV- 172 V + W+ G+ + + + PL + W+R N K+ +K V Sbjct: 113 HVVCPDSATAKIWLDGIRSITHNVKANNVCPLTCLKKHWMRLRMLIDPNG--KVPVKVVA 170 Query: 173 KAFLPKINCKISTSKLRDVFQDV---DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY 229 + F K+ L D+ D + + FD F LY K I N+++++F Sbjct: 171 RTFASGKTEKLVYQCLADLGLSSGKNDVIEPEDFTFDAFYALYHK-ICPRNDIEELFQ-- 227 Query: 230 SVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYEPY 282 S+ TI L + FL ++Q D L + DE +A + I DY ++ + Sbjct: 228 SITQGKADTINLDQLVMFLNEKQRDPTLNEILYPLYDEKRALEIINDYEQNEMAR-NQKT 286 Query: 283 FTLSEFVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 T F+ L S +N+ ++ + D V DM +PL+HY+I+SSHNTYL G QF +SS+E Sbjct: 287 MTKDGFIRYLMSDENAPVFLDRLD-VYMDMDQPLAHYYINSSHNTYLCGRQFGGKSSVEM 345 Query: 342 YVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399 Y + L +GCRC+ELDCWD G D P I HG + T I F DV+ +++ AF+TSEYP+I Sbjct: 346 YRQVLLAGCRCVELDCWDGKGEDEEPIITHGKAMCTDILFKDVIYAVRDTAFVTSEYPVI 405 Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPH 442 LS E++CS QQ ++A ++ GDLLL P+ + LPSP+ Sbjct: 406 LSFENHCSKKQQYKLAKYCDEILGDLLLKEPLKDYPLEPGVPLPSPN 452 Score = 159 bits (387), Expect = 3e-37 Identities = 99/265 (37%), Positives = 144/265 (54%), Gaps = 13/265 (4%) Query: 938 ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997 +S ++ Y + + F + + +++ MSSF ET + Q F V Y+ Q+SRIY Sbjct: 526 LSSMVNYAQPIKFPGFDVAEQKNIHHNMSSFAETAGLNYLKTQAIEF-VNYNKRQMSRIY 584 Query: 998 PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055 PKG R DSSNY P FWN G QMV+LN+QT D PMQ+N GKF+ NG G++LKP FM Sbjct: 585 PKGTRADSSNYMPQVFWNAGCQMVSLNFQTADLPMQLNQGKFEYNGSSGYLLKPDFMRRA 644 Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK-LV 1114 + ++P + ++G V ++VI + L GT +VEVE+ G D+ K Sbjct: 645 DRSFDPFAESPVDG-VIATQCSVQVIAGQFLSDKKVGT---YVEVEMYGLPTDTIRKEFR 700 Query: 1115 TKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172 T+ V NGLNP++N+ +V P+LA +RF V DE +GQ PL L+ G Sbjct: 701 TRVVPANGLNPVYNEEPFLFRKVVLPDLAALRFAVYDE---SNGKLLGQRIVPLDGLQSG 757 Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197 YR + L + + L L ++ I Sbjct: 758 YRHISLRTEANFPMSLPMLFCNIEI 782 >UniRef50_P78585 Cluster: Phosphoinositide-specific phospholipase C; n=2; Sclerotiniaceae|Rep: Phosphoinositide-specific phospholipase C - Botrytis cinerea (Noble rot fungus) (Botryotinia fuckeliana) Length = 994 Score = 180 bits (438), Expect = 2e-43 Identities = 105/283 (37%), Positives = 159/283 (56%), Gaps = 11/283 (3%) Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224 E + + V+ ++ S+ LR+ FQ D K ++ F +F + KL+ +V + Sbjct: 268 EALDFEGVEQLCKNLHINTSSRFLRERFQQADATKSKKLIFSEFQE-FVKLMKRRGDVSE 326 Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ-ASQFIRDYLRDPQRD--IYEP 281 I+ + + N ITL EF +F+ Q +N+ D + S F + R RD + E Sbjct: 327 IYRELA--SDNVKGITLEEFIDFVNVVQGENVEKDRAKWESIFAKFARRSRSRDQPLQEG 384 Query: 282 YFT-LSEFVEMLYSKQNSIYDSQYDKVTQDMT--RPLSHYWISSSHNTYLTGDQFSSESS 338 +SE E L + S+++ + V + T RP+ Y+ISSSHNTYL G Q + ESS Sbjct: 385 EAARMSE--EALATFFTSVHNVPLETVPETFTLDRPMHEYFISSSHNTYLMGRQVAGESS 442 Query: 339 LEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 +EAY+ L GCRC+E+DCWDG DG P + HGHT+T I F DV+ TI ++AF+ S +PL Sbjct: 443 VEAYISALIKGCRCVEIDCWDGKDGRPIVNHGHTMTRPIMFSDVMYTIAKYAFVKSHFPL 502 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 +S+E +C+ QQ MA ++ GDLL+ P+D + LPSP Sbjct: 503 WISLEVHCNDAQQAAMAQIIKEACGDLLVTEPLDPSSQVLPSP 545 Score = 91.1 bits (216), Expect = 2e-16 Identities = 86/311 (27%), Positives = 139/311 (44%), Gaps = 45/311 (14%) Query: 930 RTWRIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQ-ENTFFVK 987 +T +I K + +L IY V F + K YN + SF E+ +R Q + + Sbjct: 643 KTSKIVKVLGELGIYSAGVKFRGFDDPESKA--YNHIFSFMESTFDRNSKTQIDRRAMTR 700 Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK-QNGGCG 1046 ++ L R+YP G R+ S+N++P+ +W QMVALN+QT D MQ+N F G Sbjct: 701 HNMRYLMRVYPNGWRVASTNFDPLKYWRRSVQMVALNWQTHDLGMQMNDAMFAGGTDQSG 760 Query: 1047 FILKPQFMFEEGYNP-----CDKKSIEGKVKPVTVMLRVIGARHLCK----TGRGTASPF 1097 ++LKP + E P ++ + K V + +I A+ L + + P+ Sbjct: 761 YVLKPSELREIKMLPSVPEEAGADHVKRERKNVNFSIDIISAQQLMRPKGLPSNRSVDPY 820 Query: 1098 VEVEIIGADYDS----GV---------------------KLVTKTVSDNGLNPLWNDICE 1132 +EVE+ AD S GV K T V +NG NP++N Sbjct: 821 IEVEVYHADDKSKETKGVIGEGGLDASAKDGSSGLGAPHKRRTHIVQENGFNPVFNKKFN 880 Query: 1133 FEVAN--PELALIRFVVQ---DEDIFGEPNF-IGQATFPLLCLRKGYRSVPLTNAFSEEL 1186 F + PEL +R+ V+ D + + + T L L++GYR++PL + ++ Sbjct: 881 FALTTKFPELVFVRWTVRCSSDGHSYNDKTLPLATYTAKLSSLKQGYRTLPLYDTNGDQF 940 Query: 1187 ELSTLMVHLSI 1197 STL + I Sbjct: 941 LFSTLFCRVKI 951 >UniRef50_Q15147 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4; n=70; Coelomata|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 - Homo sapiens (Human) Length = 1175 Score = 180 bits (437), Expect = 3e-43 Identities = 138/413 (33%), Positives = 216/413 (52%), Gaps = 45/413 (10%) Query: 64 QGYEG-ALDIRDVKEVRTGKSSKD------FERWPEETKRLESSKCFTIYYGTEF-KLRC 115 +G EG L+ + +R+G KD E + LE + + GT+ + Sbjct: 53 EGKEGQVLECSLINSIRSGAIPKDPKILAALEAVGKSENDLEG-RIVCVCSGTDLVNISF 111 Query: 116 ASFVAQTDKECEAWVKGVLYLI----AEAVSASYPLQIERWLRKEFYSIENSHEKITLKE 171 VA+ + + WV+G+ +I A VS L+ + W++ F + N++ KI ++ Sbjct: 112 TYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLK-KHWMKLAFMT--NTNGKIPVRS 168 Query: 172 V-KAFLPKINCKISTSKLRDVFQDVDTEKRGEI-----GFDDFAVLYQKLIFDENNVQDI 225 + + F K+ L+++ + + K EI ++ F L QK I +++D+ Sbjct: 169 ITRTFASGKTEKVIFQALKEL--GLPSGKNDEIEPTAFSYEKFYELTQK-ICPRTDIEDL 225 Query: 226 FDKYSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDI 278 F K + +T+ + +FL + Q D L + D +A Q I Y +P D+ Sbjct: 226 FKK--INGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAKRAMQIIEMY--EPDEDL 281 Query: 279 YEPYFTLSE-FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES 337 + S+ F L S +N+ ++ Q+M PL+HY+ISSSHNTYLTG QF +S Sbjct: 282 KKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKS 341 Query: 338 SLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395 S+E Y + L +GCRC+ELDCWD G D P I HG + T I F DV++ IKE AF+TSE Sbjct: 342 SVEMYRQVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSE 401 Query: 396 YPLILSIEDNCSLPQQRRMASAFQDVFGDLLL-----VHPMDKNETSLPSPHD 443 YP+ILS E++CS QQ +M+ +D+FGDLLL HP++ +LPSP+D Sbjct: 402 YPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR-ALPSPND 453 Score = 166 bits (403), Expect = 4e-39 Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 14/274 (5%) Query: 931 TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990 T I +S +I Y + V F + + ++ MSSF E+ + F V Y+ Sbjct: 558 TTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEF-VNYNK 616 Query: 991 TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050 Q+SRIYPKG R+DSSNY P FWN G QMV+LNYQTPD MQ+N GKF+ NG CG++LK Sbjct: 617 RQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLK 676 Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108 P FM + ++P + ++G V T ++VI + L GT +VEV++ G D Sbjct: 677 PDFMRRPDRTFDPFSETPVDG-VIAATCSVQVISGQFLSDKKIGT---YVEVDMYGLPTD 732 Query: 1109 SGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 + K T+ V +NGLNP++N+ +V P+LA++R V D++ IGQ P Sbjct: 733 TIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDN----NKLIGQRILP 788 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199 L L+ GYR + L N ++ L L T+ ++ + T Sbjct: 789 LDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKT 822 >UniRef50_Q1LWW1 Cluster: Novel protein similar to vertebrate phospholipase C, gamma 2; n=4; Danio rerio|Rep: Novel protein similar to vertebrate phospholipase C, gamma 2 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 270 Score = 179 bits (436), Expect = 4e-43 Identities = 105/281 (37%), Positives = 154/281 (54%), Gaps = 23/281 (8%) Query: 481 KNGILHLEDPVDKEWKPHAFVLTENKLYYTESYNSQXXXXXXXXXXXXXXNAIVPQDELH 540 K G L + DP+DK + H V+++NKLYY+E + I ELH Sbjct: 2 KEGELSIWDPIDKRFYKHDCVISDNKLYYSEEKWEEQSTQ------------IKDSSELH 49 Query: 541 FAECWFHGKLAGNRQEAEDLLRAHAHLGDG---TFLVRESVTFVGDYCLSFWRQGKVNHC 597 +E WFHG+LA R AE LLR + DG TFLVRES TF+G+YC+S W +G++ H Sbjct: 50 LSEPWFHGRLAEGRITAEKLLRDYCKGTDGNDETFLVRESNTFIGNYCISLWTRGRIQHY 109 Query: 598 RIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVP----QPNKHE 653 RI E G F+L CF S+ LI +YR + F + LK +P +P H Sbjct: 110 RIFCFPENGHKIFFLKSKECFPSMCALIDYYRQQSIDYDRFNLCLKNFLPRLNFEPLHHM 169 Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713 G WF+++ +R +AE+ L + DGAFL+R E+ +FA+S R+E +IKH ++ ++ Sbjct: 170 G--WFYSNMSRAEAEDCLLRIPRDGAFLIR-KRNERDTFALSIRSEGDIKHYKIFRKSSK 226 Query: 714 YTIG-TVKFESLIELVSYYENHPLYKKVKLWYPISEETVRR 753 Y + +F SL ++VS + N K KL YP++ + V R Sbjct: 227 YVLADAYEFFSLEDMVSCFRNQQFAGKTKLRYPVTPQLVER 267 >UniRef50_Q27J08 Cluster: Phospholipase C; n=1; Aplysia californica|Rep: Phospholipase C - Aplysia californica (California sea hare) Length = 965 Score = 178 bits (434), Expect = 6e-43 Identities = 115/409 (28%), Positives = 208/409 (50%), Gaps = 29/409 (7%) Query: 2 KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 K+V F+ ++ I A ++Y++ GS ++K R R + + ++ W + Sbjct: 86 KTVSFSSMPTEKKIATAQDCLAYMQTGSELIKVRSNSRQYHRFFSLSGDVQEIRWQPTS- 144 Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKC-FTIYYGTEFKLRCASFV 119 ++ ++ + + +KEVR GK+++ +E + +C F+I +G EF+ + Sbjct: 145 --KKPHKARIAVSSIKEVRQGKTTEALRS--KEIIGVYPDECAFSIIFGEEFE--AMDLI 198 Query: 120 AQTDKECEAWVKGVLYLI-AEAVSASYPLQI-------ERWLRKEFYSIENSHEKITLKE 171 A T E W G+ L+ A + S++ I + WL + F S + + + Sbjct: 199 ASTPDEANIWTTGLTCLLNANSRSSNSSSSIGDMQRMRDSWLLELFQSASPAEGTLEEER 258 Query: 172 VKAFLPKINCKISTSKLRDVFQDVDTE----KRGEIGFDDFAVLYQKLIFDENNVQDIFD 227 V + + KIN I+ S + ++++ + KRG + ++F L++++ + +I+ Sbjct: 259 VVSLMRKINTTITPSVICQKLKELEIKRGDGKRGRLSSEEFISLFKEI----STRPEIYF 314 Query: 228 KYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD-IYEPYFTLS 286 Y SN ++ + FL EQ + + + I + +P + + + Sbjct: 315 LLVRYASNADYMSTDDLLLFLEAEQGMQRVTKD-KCLEIINKF--EPSTEGRRKGQLGID 371 Query: 287 EFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346 F L S++ ++D ++ +V QDM++PLSHY+I+SSHNTYL DQ SS++ Y+R L Sbjct: 372 GFTSYLLSEECELFDQEHSRVCQDMSQPLSHYFIASSHNTYLLEDQLKGPSSVDGYIRAL 431 Query: 347 RSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSE 395 + GCRC+ELD WDGP+ P IYHGHTLT+KI F + I ++AF SE Sbjct: 432 KKGCRCLELDVWDGPNEEPIIYHGHTLTSKISFRAAVEAINQYAFFASE 480 Score = 174 bits (423), Expect = 1e-41 Identities = 90/220 (40%), Positives = 132/220 (60%), Gaps = 10/220 (4%) Query: 985 FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044 FV ++ LSRIYP G RIDSSNYNP WNCG MVALN+QT M + G F++NGG Sbjct: 504 FVNHNKKFLSRIYPNGMRIDSSNYNPQDLWNCGCHMVALNFQTAGLMMDLYHGWFQKNGG 563 Query: 1045 CGFILKPQFMFEE-GYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTAS------PF 1097 CG+ LKP M EE Y + + + + P + +++I ++ K +G+A+ P+ Sbjct: 564 CGYTLKPAIMREEIAYFSANTRDVIPGISPQILHVKIISGQNFPKP-KGSAAKGDVTDPY 622 Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157 V +E+ G D + TKTV NG NP++++ EF++ PELAL+RF + D+D G+ Sbjct: 623 VTIEVFGIPSDCAEER-TKTVPHNGYNPIFDESFEFQINLPELALVRFAILDDDYIGD-E 680 Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 FIGQ T P C++ GYR + L + +E TL +H++I Sbjct: 681 FIGQYTIPFECMQTGYRHIQLLSNTGSVMENCTLFIHVAI 720 >UniRef50_Q21754 Cluster: Phospholipase c protein 4; n=2; Caenorhabditis|Rep: Phospholipase c protein 4 - Caenorhabditis elegans Length = 751 Score = 178 bits (433), Expect = 9e-43 Identities = 109/379 (28%), Positives = 198/379 (52%), Gaps = 13/379 (3%) Query: 72 IRDVKEVRTGKSSKDFERWPEETKRLE---SSKCFTIYYG-TEFKLRCASFVAQTDKECE 127 + ++ EVR+G + + +R ++ + E S+CF++ + +F + F A + + + Sbjct: 76 LSELLEVRSGYQTDNLQRASKKYEFQELAPESRCFSVIFSHAKFLHKSVDFSADSKETRD 135 Query: 128 AWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKINCKISTS 186 WV + +LI+ A WL +F + N + ++ EV L ++N +IS Sbjct: 136 KWVSVLTHLISVAKHQRVVFNETAWLIDKFQQADTNKNGLLSFDEVWNLLKRMNLQISER 195 Query: 187 KLRDVFQDVDTE--KRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREF 244 + +F++ + E + ++ +F +++L D +++ + + S N T+T+ + Sbjct: 196 YAKAIFRESEFENSRDNKLNEKEFLNFFERLT-DRPDLRFVMTQAS--SDNVETLTVADL 252 Query: 245 QNFLRDEQ-HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQ 303 Q FL +EQ +N+ D +A Q + + + Q E L ++ S+ +++ Sbjct: 253 QRFLTEEQGFENV--DLKKAEQILTTFEQTVQDKQKEKLMGLMGMRRLMQSRWGNVFKPG 310 Query: 304 YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG 363 ++ + QDM +PL+HY+++SSHNTYLTG Q E+++E Y+ LR G R +ELD +DG G Sbjct: 311 HESIFQDMDQPLTHYFVNSSHNTYLTGLQVKGEATVEGYISALRKGARLLELDLFDGEHG 370 Query: 364 TPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFG 423 P I H T I + L IK AF TS YP+IL++E++ QQ MA F+++ G Sbjct: 371 EPVITHKRTFIESITLRNSLEAIKRTAFETSPYPVILTLENHVGFVQQAVMADLFKEILG 430 Query: 424 DLLLVHPMDKNETSLPSPH 442 D L + P D + L SP+ Sbjct: 431 DSLYIPPKDSHRHPLSSPN 449 Score = 142 bits (345), Expect = 4e-32 Identities = 82/260 (31%), Positives = 139/260 (53%), Gaps = 16/260 (6%) Query: 947 SVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFF------VKYHTTQLSRIYPKG 1000 S + +++ +Y +++ P + L + T F Y +L + YPKG Sbjct: 495 SALIGLPSVKLSHNIYQDVNKHPFDGSPSLSENKVYTMFEAAVPIFTYTAERLVKSYPKG 554 Query: 1001 QRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYN 1060 R DSSN +P+ W CG Q VA+N+QT + + +N G F+ NG CG++LKP + +G + Sbjct: 555 LRQDSSNMHPMVSWLCGIQSVAMNFQTAGEELDLNAGLFRINGNCGYVLKPSCLL-DGVD 613 Query: 1061 PCDKKSIEGKVKPVTVMLRVIGARHLCKT--GRGTASPFVEVEIIGADYDSGVKLVTKTV 1118 P + + K+K + + + A++L K+ G+ P+V V+I G D K T+ + Sbjct: 614 P--RSMAKPKLK---LGIGLFSAQYLPKSEPGKEIIDPYVSVQIFGIPRDE-TKAKTRII 667 Query: 1119 SDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 DNG NP W D F ++ PELA+IRF V+D D +F+G+ + P++ LR G+ + L Sbjct: 668 KDNGFNPEWRDNFYFTLSCPELAIIRFCVKDFDSTSSNDFVGEFSIPVMSLRTGFSQIQL 727 Query: 1179 TNAFSEELELS-TLMVHLSI 1197 + L+ S +L V +++ Sbjct: 728 NTGYQHTLDPSASLFVRIAM 747 >UniRef50_UPI00006CB024 Cluster: Phosphatidylinositol-specific phospholipase C, X domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Phosphatidylinositol-specific phospholipase C, X domain containing protein - Tetrahymena thermophila SB210 Length = 850 Score = 176 bits (429), Expect = 3e-42 Identities = 92/283 (32%), Positives = 163/283 (57%), Gaps = 16/283 (5%) Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224 + +T +E + K+N IS L + FQ D + ++F + + L+ ++ + Sbjct: 157 DNLTYEECLNLIQKLNVNISKKDLLEKFQFYDENNDKLLQVNEFVEIIRDLL-SKSELMP 215 Query: 225 IFDKYSVYCS-----NGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIY 279 +F KY + N + F F++ EQ + ++++ QF+ Y + I Sbjct: 216 LFKKYVPSFNEKSNLNSPAMKKETFFKFMKAEQKQE--EIDLKSQQFLDMYFAEKNNII- 272 Query: 280 EPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSL 339 + ++F+ ++++ QN+IYD V QDM +PL+ Y+I+SSHNTYL +Q + ES++ Sbjct: 273 ----SYNDFINLIFNYQNNIYDPAKLSVYQDMDQPLTDYFINSSHNTYLMANQLTGESNV 328 Query: 340 EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399 +AY+ R GCRCIE+D WDG + P + HG TLT+ I+F DV++TIK + F+ S+YP+I Sbjct: 329 QAYINAFRKGCRCIEIDVWDGSE--PIVTHGFTLTSSIKFRDVVQTIKTYGFVWSKYPII 386 Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSL-PSP 441 +SIE++C+ Q++MA+ +++FG + + P + + PSP Sbjct: 387 ISIENHCNQENQKKMANIMKEIFGSSIYLIPENYSSMKFYPSP 429 Score = 128 bits (309), Expect = 9e-28 Identities = 87/276 (31%), Positives = 147/276 (53%), Gaps = 27/276 (9%) Query: 948 VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSN 1007 V+F ++ ++ + ++ S E K + L+ + E V YH SRIYPKG R+DSSN Sbjct: 573 VSFTMDMIKFQNGSIFDIFSLSEEKIKYLLKKHEK-IIVDYHKKFFSRIYPKGSRVDSSN 631 Query: 1008 YNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM--------FEE 1057 ++P+P + GSQ++ALN+QT D M + + KF+QNGG G++LKP+++ + Sbjct: 632 FDPLPSFISGSQIIALNFQTCDYHMLMYLSKFQQNGGIFSGYVLKPKYLRHSHIQQINSD 691 Query: 1058 GYNPCD---------KKSIEGKVKPV-TVMLRVIGARHLCKTGRGTAS--PFVEVEIIGA 1105 + CD +K VK + + + +I + L + + S PF+EV + G Sbjct: 692 DHKLCDDLNKNKNTLQKYPSDFVKQIKEIKITIISGQCLKREEDDSKSFNPFIEVSLKGT 751 Query: 1106 DYD--SGVKLVTKTVSDNGLNPLWNDI-CEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 + D + TK++++N +P++N F+VA PELA+I F V I F Q Sbjct: 752 ELDEKNNKTQRTKSINNNTFHPIFNSSPITFKVACPELAMISFQVFSNGIIKNELF-AQY 810 Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 C+R+GYR +PL + +++E L+ H+ I+ Sbjct: 811 ALDFECIREGYRIIPLWDKEFKKIEHGMLLAHIEIL 846 >UniRef50_A2TJ25 Cluster: Phospholipase C beta 3; n=8; Clupeocephala|Rep: Phospholipase C beta 3 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1244 Score = 175 bits (427), Expect = 5e-42 Identities = 105/266 (39%), Positives = 152/266 (57%), Gaps = 13/266 (4%) Query: 936 KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995 +E+S L+ Y V F + K + EMSSF ETK + T FV+Y+ Q+SR Sbjct: 568 EEMSTLVNYIEPVKFKSFEVAAKRKKFFEMSSFVETKGMDTLKNSP-TEFVEYNKKQMSR 626 Query: 996 IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM- 1054 IYPKG R+DSSNY P FWN G QMVALN+QT D MQ+NMG F+ NG CG++LKP+FM Sbjct: 627 IYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLAMQLNMGVFEYNGRCGYLLKPEFMR 686 Query: 1055 -FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKL 1113 ++ ++P ++G V TV +++I + L G +VEV++ G D+ K Sbjct: 687 RTDKHFDPFTTDIVDGIVAN-TVKVKIISGQFLNDKKVGV---YVEVDMFGLPADTKRKY 742 Query: 1114 VTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171 TKT ++N L+P+W+D +V P LA +R V +E+ FIG P+ LR Sbjct: 743 RTKTSNNNSLDPVWDDETFVFNKVVLPTLASLRVAVYEEN----GKFIGHRILPVSALRP 798 Query: 1172 GYRSVPLTNAFSEELELSTLMVHLSI 1197 GY + L N ++ L L +L+V+ + Sbjct: 799 GYHYICLKNELNQPLMLPSLLVYTEV 824 Score = 168 bits (409), Expect = 7e-40 Identities = 127/430 (29%), Positives = 205/430 (47%), Gaps = 32/430 (7%) Query: 70 LDIRDVKEVRTGKSSKD--FERWPE-----ETKRLESSKCFTIYYGTEF-KLRCASFVAQ 121 LD+ +++ RTGK +K +R E + S+ T+ YG + + +F A Sbjct: 66 LDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAV 125 Query: 122 TDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KAFLP 177 D C+ W + L +S + +L K + ++ KI +K + K F Sbjct: 126 QDGYCKLWTDELFKLATNMLSQN--ASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD 183 Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237 K +++ +F VD K + ++ F KL V+ IF + Sbjct: 184 KKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLS-PRPEVERIF--VDLGSKGKP 240 Query: 238 TITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSEFVE 290 ++L + +F+ +Q D+ ++ + Q Q + Y + + + +L F + Sbjct: 241 FLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQ-LERDQISLMSFTK 299 Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350 L ++N++ + + DM +PLSHY+I+SSHNTYLT Q + SS+E Y + L +GC Sbjct: 300 YLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGC 359 Query: 351 RCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-S 407 RCIELDCW G P+ P I HG T+TT+I F DV+ I E AF TS YPLILS E++ S Sbjct: 360 RCIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDS 419 Query: 408 LPQQRRMASAFQDVFGDLLLVHPMDKNE----TSLPSPHDXXXXXXXXXXXXPEGAEESS 463 QQ +MA + +FGD LL+ P+DK LPSP + + Sbjct: 420 AKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNG 479 Query: 464 FAVRQEEGKD 473 ++R+++G D Sbjct: 480 GSIRRKDGTD 489 >UniRef50_Q5MG88 Cluster: Phospholipase C delta 1; n=2; Toxoplasma gondii|Rep: Phospholipase C delta 1 - Toxoplasma gondii Length = 1097 Score = 174 bits (424), Expect = 1e-41 Identities = 119/422 (28%), Positives = 210/422 (49%), Gaps = 29/422 (6%) Query: 19 QLISYIERGSTVLKFFPR--KRPERRALCVRRETHQVLWSRINAPQRQGYEGALDIRDVK 76 + + + GS +LK+ K+P R V + W +P++ + + DV+ Sbjct: 128 EALQTLAEGSFLLKWCKTNFKKPHERFFYVDANAMALKW---RSPKKPESVTTIPVGDVQ 184 Query: 77 EVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYL 136 + G+ + DF R K +S + G + C + +KE W+KG+L Sbjct: 185 RIIPGEDT-DFGR----NKADKSHSIEIVATGRVLHVAC-----RDEKEWRLWMKGLLLY 234 Query: 137 IAEAVSASYPLQIERWLRKEFYSIENSHE-KITLKEVKAFLPKINCKISTSKLRDVFQDV 195 A+ ++ +++++E + KI + + L K+N + + ++FQ Sbjct: 235 HDMALGQLASEGASDFVSAQWHAVEKDADGKIDQRHLHGLLRKLNIQADGRYVEELFQTH 294 Query: 196 DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQH-D 254 DTE G +GF +F + +L+ +V F Y + + I + ++ FLR+ Q Sbjct: 295 DTENSGRLGFTEFREMLNELLV-RPDVDYYFTVYKL--PHEDFIDEQGYRRFLREVQKVT 351 Query: 255 NLGDDEVQASQF--IRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT 312 + + E + + F + + R P + + F +L + NS+ KV QDM+ Sbjct: 352 SEAEVEEELASFCSVDEAFRKPGPTVM---VSSLGFDNLLCGEANSLMAPHRMKVHQDMS 408 Query: 313 RPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYH--- 369 PL +YW+ SSHNTYL GDQ +S++ Y+ L GCRC+ELDCWDG DG P ++H Sbjct: 409 LPLCNYWVKSSHNTYLCGDQVVGKSAVGQYIDALLRGCRCVELDCWDGSDGEPSLFHGVG 468 Query: 370 GHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD-LLLV 428 G+ LT++I+F DV++ K++ F S++P+ILS+E +CS Q+ R+A +++ D + Sbjct: 469 GYQLTSRIKFKDVIQACKDYGFQRSKFPIILSLEMHCSTKQRIRIAEILEEILQDQIYRC 528 Query: 429 HP 430 HP Sbjct: 529 HP 530 Score = 107 bits (257), Expect = 2e-21 Identities = 89/282 (31%), Positives = 133/282 (47%), Gaps = 30/282 (10%) Query: 944 YCRSVTFNIERLRIKGFVYNEMS--SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQ 1001 Y R++ ++LR N M S PE++ +L+ Q F ++ L+R+YP G Sbjct: 789 YYRNIAMPGKKLRSFEQARNPMDICSMPESRLLKLVKQSP-VEFASFNQRFLTRVYPAGT 847 Query: 1002 RIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFMFEEG- 1058 R+ SSN++PV W G+Q+VALN Q+ +N G+F NGG G++LKP+ M Sbjct: 848 RLQSSNFSPVVPWLFGAQVVALNLQSLGSATILNEGRFLDNGGPAGGYVLKPEMMRNPAR 907 Query: 1059 -YNPCDKKSIEGKVKPVTVMLRVIGARHL----------------CKTGRGT--ASPFVE 1099 + P + + PV ++++ A L KT + T + PFV Sbjct: 908 PFVPAFAELSACRETPVHFTIKILSAHQLPRPVTDPWKGPSTINKIKTRKSTDLSCPFVS 967 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNPLWN---DICEFEVANPELALIRFVVQDEDIFGEP 1156 V I G D+ T TV +NG NP W+ EF V P +AL+ F VQ D Sbjct: 968 VSIHGVKEDTKA-FRTSTVMNNGFNPRWSSPESTFEFIVHAPSVALLVFKVQTADSV-RS 1025 Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 F+ A FP +R G R VPL + L + L+V+ I+ Sbjct: 1026 EFLAAACFPFDAIRPGIRWVPLFDRKFCRLRWTGLLVYSRIV 1067 >UniRef50_Q9TZN8 Cluster: Phosphoinositide-specific phospholipase C; n=5; Trypanosoma|Rep: Phosphoinositide-specific phospholipase C - Trypanosoma cruzi Length = 725 Score = 174 bits (423), Expect = 1e-41 Identities = 99/210 (47%), Positives = 130/210 (61%), Gaps = 11/210 (5%) Query: 238 TITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQN 297 TIT EF++FLR+ Q + L + V+ I DY+ + E YFT F++ L + Sbjct: 180 TITRDEFKSFLRNYQGEELNGERVKE---ILDYVCCMKTG--EVYFT--NFLKFLEDNRF 232 Query: 298 -SIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355 SI D + KV QDM +P+ +Y+I+SSHNTYLTGDQ +S SS + Y + L GCRC+EL Sbjct: 233 CSIVDEEKVSKVYQDMNQPICNYFINSSHNTYLTGDQLTSNSSADMYRKALLDGCRCVEL 292 Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415 DCWDG G P +YHGHT T+KI F+ ++ IKE+AF SEYP+ILSIE + S Q RMA Sbjct: 293 DCWDGFAGEPIVYHGHTRTSKISFLSCIKVIKEYAFKASEYPVILSIEVHTSSAQADRMA 352 Query: 416 SAFQDVFGDLLLVHPMDKNE--TSLPSPHD 443 D FGD+L P E T L SP + Sbjct: 353 EIMCDTFGDMLFQSPWAPAEPTTFLFSPEN 382 Score = 110 bits (264), Expect = 3e-22 Identities = 78/226 (34%), Positives = 115/226 (50%), Gaps = 21/226 (9%) Query: 964 EMSSFPETKAERLMSQQENTF-FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVA 1022 + +SF E+KA+++ F + H LSRIYP G R+ SSNYNP FWNCG Q+VA Sbjct: 490 QCTSFVESKAKKIAVSNAMEFKLINQHC--LSRIYPAGSRVGSSNYNPQLFWNCGCQIVA 547 Query: 1023 LNYQ-TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVI 1081 LN+Q T ++N G F NG CG++LKP+ + S G + ++ L +I Sbjct: 548 LNWQSTHTYAWRLNKGFFSDNGNCGYVLKPESVRSSA------ASRNGS-QVRSLNLEII 600 Query: 1082 GARHLCKTGRGT----ASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI---CEF- 1133 L K R PF+ I G D +S K + T+ +NG +P+W EF Sbjct: 601 SGFCLPKPKRSNKGEIVDPFITCFIEGPDGNSDRK-TSGTIRNNGFHPVWRGKGLGTEFS 659 Query: 1134 -EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 +V + +L+ + V DED +F+ + PL L+ G R +PL Sbjct: 660 WDVKDWDLSTLVVQVYDEDKKTRDDFLAECILPLRVLKAGIRQIPL 705 >UniRef50_Q8IA75 Cluster: Phospholipase c like protein 1, isoform a; n=3; Caenorhabditis|Rep: Phospholipase c like protein 1, isoform a - Caenorhabditis elegans Length = 1075 Score = 173 bits (420), Expect = 3e-41 Identities = 104/275 (37%), Positives = 154/275 (56%), Gaps = 17/275 (6%) Query: 933 RIAKEISDLI-IYCRSVTFNIERLRIKGFVY----NEMSSFPETKAERLMSQQENTFFVK 987 ++ KE+SDL+ ++ T N G ++S E+ RLM T F + Sbjct: 547 QLCKELSDLVPVFFNVKTLNDLLSTAPGSTTMSSRKNLASVTESTCLRLMHTYA-TEFGQ 605 Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047 R++P R+DSSN NP FWN G QMV LNYQTP M + GKF NGGCG+ Sbjct: 606 ATRNYCVRVFPNPSRVDSSNLNPQEFWNNGVQMVCLNYQTPGLMMDLQEGKFSDNGGCGY 665 Query: 1048 ILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK----TGRG-TASPFVEVEI 1102 +LKPQ M ++ + P D+ P + LR++ + L + +G +A PFV VE+ Sbjct: 666 VLKPQVMKDDMFVPSDRV----PTSPQILHLRILSGQQLPRPRGSNAKGDSADPFVVVEV 721 Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 G D + T+TV ++ +NP +++ +F+V+ PELAL+RF+V D+D G+ +FIGQ Sbjct: 722 FGLPGDCAEER-TRTVRNDSINPSFDESFQFQVSVPELALVRFLVLDDDYIGD-DFIGQY 779 Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 T P CL+ GYR + L N + LE +TL VH++I Sbjct: 780 TIPFECLQPGYRHIYLLNNEGDPLEHATLFVHVAI 814 Score = 149 bits (361), Expect = 5e-34 Identities = 122/462 (26%), Positives = 206/462 (44%), Gaps = 34/462 (7%) Query: 2 KSVCFNGAK-DRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 K+V F+ D I +Y++ GS +K R RR + + + W+ N Sbjct: 59 KTVSFSSKNSDAKISNVSDCWNYMQTGSDFVKLRGTNRQFRRFFSLDADLSYIRWTPTN- 117 Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 ++ ++ + I +++E+R GK+++ E L+ F+I YG ++ +A Sbjct: 118 --KKPHKARIAIDEIREIRLGKNTELLRSSDEVFTDLQEECLFSIIYGDNYET--LDLIA 173 Query: 121 QTDKECEAWVKGVLYLIAEAV-----SASYPLQIERWLRK---EFYSIENSH--EKITLK 170 + + WV G++ L + S+ + ERW+ EF + +N H E+ K Sbjct: 174 SSGDDANIWVTGLMALTSNKYECKPSSSQFATLRERWIESVFDEFDTKKNGHLDEQTAFK 233 Query: 171 EVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYS 230 + +I+ T+KL++V + +RG+I F LY++ I V + +Y+ Sbjct: 234 AILHINSRISHHRLTNKLKEVTIGAEESERGKIEKSHFVDLYKE-IGTRPEVYFLMVRYA 292 Query: 231 VYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFV 289 N ++ ++ + FL EQ +G I Y +P + E T+ F Sbjct: 293 ----NKDYLSCQDLRLFLETEQ-GMVGVTTDNCETLIEQY--EPCSEARENNLMTVDGFT 345 Query: 290 EMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSG 349 L+S ++D + VT DM +P S Y+ISSS +YL DQ SS + + L+ Sbjct: 346 SFLFSPDCGVFDPNHRVVTMDMKQPFSRYFISSSRKSYLVEDQLGPSSS-DGFSSALKRN 404 Query: 350 CRCIELDCWD----GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405 CR +E D WD D P + +G T T+KI LR I+E AF S YPL+L + + Sbjct: 405 CRFLEFDIWDPNEADGDTEPMVQNGQTATSKITISSALRIIREFAFERSRYPLLLKVSVH 464 Query: 406 CSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443 CS Q+ A G L + D +E + P+P D Sbjct: 465 CSTDWQKVAAMLIVTHLGTRLYLPKNDPTNWDDEKNCPTPWD 506 >UniRef50_O97036 Cluster: PLC-betaH2; n=2; Eukaryota|Rep: PLC-betaH2 - Hydra magnipapillata (Hydra) Length = 1364 Score = 172 bits (419), Expect = 4e-41 Identities = 125/394 (31%), Positives = 209/394 (53%), Gaps = 34/394 (8%) Query: 71 DIRDVKEVRTGKS-SKDFERWPEETKR-LESSKCFT-IYYGTEF-KLRCASFVAQTDKEC 126 DI VK+ T K+ +K FE++ +E K ++ FT I +GT ++ +F T + Sbjct: 65 DISYVKDGATPKALNKVFEQYSDEEKNNVDFLSRFTYICFGTNIVEVSFITFDFMTKELK 124 Query: 127 EAWVKGVLYLIAEAVSASYPLQIERWLRKEFY---SIENSHEKITLKEVKAFLPKINCKI 183 + + + + A +++ L K++ S+ N+ KI++K + L + + Sbjct: 125 QIFFSCISTNLTNHKHAFRNPSVKQMLYKQYVLSKSMVNASGKISMKNIFKCLNAVRFEQ 184 Query: 184 ST-----SKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238 +T + L ++D E F+ F L L+ ++ ++F S++ GT Sbjct: 185 TTIEGIQTALSLPVGEIDPEM---FSFEQFYKLCC-LVCPRPDIDELF--ISLF---GTR 235 Query: 239 ITLREFQNFLRDEQHDNLGDDEVQ-------ASQFIRDYLRDPQRDIYEPYFTLSEFVEM 291 +T + FL ++Q D ++++ A I DY + E T+ F+++ Sbjct: 236 LTAEKLMKFLNEDQRDPRLNEQMHPHCTISNAVDLIMDYESNEACRTKE-LLTIQGFIQL 294 Query: 292 LYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCR 351 L SK++++ + + + DM +P++HY+I+SSHNTYL G Q +SS+E Y + L SGCR Sbjct: 295 LLSKESAVLNPECLLLRHDMNQPINHYFINSSHNTYLLGRQVYGKSSVEIYRQVLISGCR 354 Query: 352 CIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQ 411 CIELDCWDGP G P I HG + T + F DV++ I + AF+TS YP++LS E++CSLPQQ Sbjct: 355 CIELDCWDGP-GVPIITHGKAMCTNVLFSDVVQAIADTAFLTSPYPVVLSFENHCSLPQQ 413 Query: 412 RRMASAFQDVFGDLLLVHPMDKNE----TSLPSP 441 + +A +FG LLL P++ N LPSP Sbjct: 414 KILAEMCIKIFGPLLLDKPLESNPLEPGIELPSP 447 Score = 138 bits (333), Expect = 1e-30 Identities = 91/248 (36%), Positives = 131/248 (52%), Gaps = 22/248 (8%) Query: 958 KGFVYNE-------MSSFPETKAERLMSQQEN-TFFVKYHTTQLSRIYPKGQRIDSSNYN 1009 KGF Y E MSSF E E L EN T FV Y+ Q SRIYPK R++S+NY Sbjct: 704 KGFEYAEEQKKHYIMSSFSEL--EGLKQCTENLTDFVLYNKRQFSRIYPKATRVESTNYV 761 Query: 1010 PVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFE--EGYNPCDKKSI 1067 P FWN G Q VALN QTPD +Q+N KF+ N CG++LKP E ++P + I Sbjct: 762 PQVFWNAGCQFVALNLQTPDLSVQLNQQKFECNFNCGYLLKPVKYRETDSNFDPLTENPI 821 Query: 1068 EGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW 1127 +G + P+TV + VI ++L + +V++++ G D+ K T N +N ++ Sbjct: 822 DG-IIPLTVEIEVISGQYLSEK---KCMTYVQIDMFGLSADTTRKKRTNLSESNLMNTVY 877 Query: 1128 -NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185 + +F+ + PE+ L+RF V DE +GQ PL ++ GYR + + Sbjct: 878 PKTVFKFDKIVFPEMVLVRFTVYDE----SDKLLGQRVLPLEGIKSGYRHIAMRTETGHF 933 Query: 1186 LELSTLMV 1193 L L+TL V Sbjct: 934 LPLTTLFV 941 >UniRef50_Q9NBA8 Cluster: Phospholipase C; n=3; Decapodiformes|Rep: Phospholipase C - Loligo pealeii (Longfin squid) Length = 1127 Score = 171 bits (416), Expect = 1e-40 Identities = 115/362 (31%), Positives = 182/362 (50%), Gaps = 23/362 (6%) Query: 101 KCFTIYYGTEF-KLRCASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFY- 158 KC TI +G + L VA+ W + V +S + Q+ W + F Sbjct: 104 KCVTICHGYNYIDLDWIHLVAENSSVAAKWAEEVFSYAYNLLSLNKN-QLGEWEKLYFRL 162 Query: 159 -SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV-------DTEKRGEIGFDDFAV 210 ++E KI +K ++ L K K +++ + + D + FD F Sbjct: 163 TTVEMEKNKIPVKSIQKCLSKD--KDDRTRVAKAIEKIGWPSGKNDAIEIKAFDFDTFFK 220 Query: 211 LYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ--HDNLGD--DEVQASQF 266 Y L+ + + ++ IF + S N TT+ R+F N ++ H L + Q Sbjct: 221 FYLSLL-ERSEIEGIFKELSQNKGNITTVMFRDFLNDMQRHPSLHKTLFPLYTDSQCDAL 279 Query: 267 IRDYLRDP-QRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHN 325 I +Y ++ + T + L ++N++ + +M L+ Y+I+SSHN Sbjct: 280 INEYESAVNKKGKKKGQLTKEGLLYFLMCEENNLTPMHRLDLGANMKLSLAAYYINSSHN 339 Query: 326 TYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRT 385 TYLTG Q + +SS+E Y + L +GCRC+ELDCWDG DG P I HG T+ T+++F DV+ Sbjct: 340 TYLTGHQLTGKSSVEIYRQVLLTGCRCLELDCWDGKDGEPIITHGFTMCTEVQFKDVVHA 399 Query: 386 IKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSP 441 I E AF SEYP+ILS E++CS+PQQ+ +A + FG+LLL +P+D K LP+P Sbjct: 400 IAECAFKVSEYPVILSFENHCSVPQQKLLAQYCHEAFGELLLDNPIDGHPLKPGVPLPTP 459 Query: 442 HD 443 +D Sbjct: 460 YD 461 Score = 165 bits (402), Expect = 5e-39 Identities = 101/267 (37%), Positives = 157/267 (58%), Gaps = 16/267 (5%) Query: 935 AKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKA-ERLMSQQENTFFVKYHTTQL 993 A+E+S L+ Y + V F K + EMSS ET+A +L E+ FV Y+ QL Sbjct: 511 AEEMSALVNYIQPVHFTTFEQAQKKDRHYEMSSMVETQALNKLKDNPED--FVDYNKKQL 568 Query: 994 SRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQF 1053 +RIYPKG R+DSSNY P +WN G Q+VALN+Q D M VN+G F+ NG G++LKP+F Sbjct: 569 TRIYPKGTRVDSSNYVPQIYWNAGCQLVALNFQCFDVAMCVNLGVFEYNGCSGYLLKPEF 628 Query: 1054 M--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDS-G 1110 M ++ ++P + +++G V T+ +++I A+ L S +VEVE+ G D+ Sbjct: 629 MRKLDKRFDPFTESTVDGVVAG-TIEIKIISAQFLSDK---QISSYVEVEMYGLPTDTVR 684 Query: 1111 VKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168 K TKTV++NG++P +N+ +V P+LA++R +V ++ FIG PL Sbjct: 685 KKFKTKTVNNNGMDPYYNENAFVFKKVVLPDLAVVRIIVNEDG----GKFIGHRLMPLDG 740 Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHL 1195 ++ GYR +PL N + L L+++ H+ Sbjct: 741 IKPGYRHIPLRNESNRPLGLASVFAHI 767 >UniRef50_Q4S530 Cluster: Chromosome 6 SCAF14737, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 6 SCAF14737, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 767 Score = 171 bits (415), Expect = 1e-40 Identities = 78/163 (47%), Positives = 109/163 (66%), Gaps = 2/163 (1%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 + T F+ L+ + I + + QDM +PL+HY+ISSSHNTYL DQ SS EA Sbjct: 212 HMTKDGFLMYLHQDEGYILNPAHKHQYQDMRQPLNHYFISSSHNTYLMEDQLKGPSSTEA 271 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401 Y+ CRC+ELDCWDGP+G P IYHG+T+T+K+ F DV++ IK++AF TS+YP+ILS Sbjct: 272 YINTDEE-CRCVELDCWDGPNGEPIIYHGYTITSKVLFRDVIKAIKDYAFKTSQYPVILS 330 Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKN-ETSLPSPHD 443 +E++CS+ QQ+ MA + GD LL P+ K+ + PSP D Sbjct: 331 LENHCSVDQQKLMAHHLISILGDALLTAPLGKSLPSEFPSPED 373 Score = 89.8 bits (213), Expect = 4e-16 Identities = 43/88 (48%), Positives = 60/88 (68%), Gaps = 1/88 (1%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 ++AKE+SD++IYC+SV F+ + + EMSSF E+KA L ++ T F+ ++ + Sbjct: 426 KLAKELSDIVIYCKSVHFSSFEHARENQAFYEMSSFKESKAFSL-AETSATAFMHHNMDK 484 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQM 1020 LSRIYP G R DSSNYNPVP WN G Q+ Sbjct: 485 LSRIYPAGSRTDSSNYNPVPMWNVGCQI 512 Score = 80.6 bits (190), Expect = 2e-13 Identities = 42/123 (34%), Positives = 67/123 (54%), Gaps = 5/123 (4%) Query: 1079 RVIGARHLCKTGR----GTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFE 1134 +VI A+ L K + P V VE+ G D+ K T +S+NG NP+WN +F+ Sbjct: 646 QVISAQQLPKLNKDKQKSIVDPLVRVELYGVPADNASK-ETHHISNNGFNPMWNQRFQFD 704 Query: 1135 VANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194 + PEL ++RFVV+D D + + IGQ PL ++ GYR VP+ + + + L ++ Sbjct: 705 IHVPELVMVRFVVEDYDATSQNDLIGQYCLPLTSIQNGYRHVPILTKRGDVISSAGLFLN 764 Query: 1195 LSI 1197 L + Sbjct: 765 LML 767 Score = 47.2 bits (107), Expect = 0.003 Identities = 41/206 (19%), Positives = 91/206 (44%), Gaps = 10/206 (4%) Query: 1 MKSVCFNGAKDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 +K V K RL E D + ++ +G ++K + R ++ + + +W + Sbjct: 22 VKKVAQENGK-RLGLEGDADVQFLLQGGELVKVRSTTWKKMRFFKLQEDC-KTIWHESH- 78 Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 +R + I ++ +R G+ S+ + T ++ +CF+I + + + + +A Sbjct: 79 -KRFNRDQTFSIDEIDSLRLGRQSEGLNK---HTHPVDEDQCFSIIF--KGRKKNLDLMA 132 Query: 121 QTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE-NSHEKITLKEVKAFLPKI 179 + WV G+ +I + S+ + E W+ + N K+ LKE+K FL +I Sbjct: 133 PNGEVARKWVNGMEKIINNMRNLSHVQKSEHWIINCMRKADKNEDNKMNLKELKHFLRQI 192 Query: 180 NCKISTSKLRDVFQDVDTEKRGEIGF 205 N +++ ++F+ + + GF Sbjct: 193 NIEVNDVYAEELFKQSTNKHMTKDGF 218 >UniRef50_O97035 Cluster: PLC-betaH1; n=1; Hydra magnipapillata|Rep: PLC-betaH1 - Hydra magnipapillata (Hydra) Length = 1012 Score = 170 bits (414), Expect = 2e-40 Identities = 108/264 (40%), Positives = 152/264 (57%), Gaps = 13/264 (4%) Query: 936 KEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSR 995 +E+S+L+ Y + V F K Y EMSSF E A L+ +Q FV Y+ Q SR Sbjct: 533 QELSELVNYFQPVHFRGFEKAEKRKCYYEMSSFGENTATNLLKEQP-VEFVNYNKFQNSR 591 Query: 996 IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM- 1054 IYPKG R+ S NY P FWN G QMVALN+QT D PMQ+N+GKF+ NG CG++LKP+ M Sbjct: 592 IYPKGSRVSSDNYIPQLFWNAGCQMVALNFQTLDVPMQLNLGKFEINGRCGYLLKPEHMR 651 Query: 1055 -FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDS-GVK 1112 + ++P +++G + TV ++VI + L + GT +VEVE+ G D+ K Sbjct: 652 RHDLTFDPFVDSTVDGIIAG-TVQVKVISGQCLLERRSGT---YVEVEMYGLPADTVRRK 707 Query: 1113 LVTKTVSDNGLNPLWN-DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK 1171 TK VS+NGLNP+++ D +F+V P LA +R V +E+ IG P+ L Sbjct: 708 YRTKVVSNNGLNPVYDEDPFKFKVILPHLAELRIAVYEEN----GKMIGHRILPVDGLLP 763 Query: 1172 GYRSVPLTNAFSEELELSTLMVHL 1195 G+R + L N + L L TL V + Sbjct: 764 GFRHIKLRNESYQPLCLPTLFVDI 787 Score = 163 bits (397), Expect = 2e-38 Identities = 119/370 (32%), Positives = 188/370 (50%), Gaps = 24/370 (6%) Query: 92 EETKRLESSKCFTIYYGTEF-KLRCASFVAQTDKECEAWVKGVLYLIAEAVSA-SYPLQ- 148 E L + TI YG+ F L +FVA + E + W + + + S PL+ Sbjct: 99 ELESNLMQERTITIVYGSNFVDLTFINFVASSVSEAQEWTEALFKCTNNLLEFHSSPLKC 158 Query: 149 IERWLRKEFYSIENSHEKITLKE-VKAFLP-KINCKISTSKLRDV---FQDVDTEKRGEI 203 +ER+ + +N + +I +K VKAF+ K + K + L+ + D + Sbjct: 159 LERFYTRICVQ-KNQNGEIPVKILVKAFVNHKEDIKRAYGTLQSLGIAHGKKDMIVLKDF 217 Query: 204 GFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDD---- 259 F+ F Y +LI ++ ++F + N +T + FL + Q D ++ Sbjct: 218 SFETFFTFYNRLI-SRHDFDNVFTELGA--KNKPYLTTDQLVEFLNNRQRDPRLNEILFP 274 Query: 260 --EVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSH 317 + A+ I + + + ++ ++ L S ++ + QD++ P++H Sbjct: 275 YYNINAADAIVNTYEPNKSFADKGLISIDGLMKFLMSNDANVLLPGKLNIHQDLSFPIAH 334 Query: 318 YWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTT 375 Y+I+SSHNTYL G Q + +SS+E Y + L +GCRCIELDCWDG + P I HG TL T Sbjct: 335 YFINSSHNTYLQGHQLTGKSSVEIYRQVLLAGCRCIELDCWDGKTEEQEPVITHGMTLCT 394 Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNE 435 ++ F DV+ IKE AF TSEYP+ILS E++CS QQ +MA+ +FGDLLL +D+ Sbjct: 395 EVLFKDVIEAIKESAFKTSEYPVILSFENHCSAKQQMKMANYCLQIFGDLLLNKELDEYP 454 Query: 436 ----TSLPSP 441 T LPSP Sbjct: 455 LLPGTLLPSP 464 >UniRef50_UPI000065E6FA Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon 1 (EC 3.1.4.11) (Phospholipase C-epsilon-1) (PLC-epsilon-1) (Phosphoinositide-specific phospholipase C epsilon-1) (Pancreas- enriched phospholipase C).; n=9; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon 1 (EC 3.1.4.11) (Phospholipase C-epsilon-1) (PLC-epsilon-1) (Phosphoinositide-specific phospholipase C epsilon-1) (Pancreas- enriched phospholipase C). - Takifugu rubripes Length = 1761 Score = 169 bits (412), Expect = 3e-40 Identities = 88/205 (42%), Positives = 127/205 (61%), Gaps = 10/205 (4%) Query: 243 EFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEP-YFTLSEFVEMLYSKQNSIYD 301 + +FL + Q ++L DE+ + I+ + +P + + + + F L K N Sbjct: 833 QLNDFLVNCQREHLSYDEILS--IIQKF--EPSSSMRQMGWMSFEGFSRFLMDKDNFASH 888 Query: 302 SQYDKVT-QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360 + ++ +++ PLS+Y+I SSHNTYLTG Q ESS+E Y + L GCR +ELDCWDG Sbjct: 889 IEESQMNPEELQHPLSYYYIQSSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDG 948 Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420 DG P IYHGHTLTTKI F DV+ I AF+ S P++LSIE++CSLPQQR+MA F+ Sbjct: 949 DDGMPVIYHGHTLTTKIPFKDVVEAISRSAFVNSNMPVVLSIENHCSLPQQRKMAEIFKT 1008 Query: 421 VFGDLLLVHPMDKNETS----LPSP 441 VFG+ L+ + +++ S LPSP Sbjct: 1009 VFGERLVTRFLFESDFSDDPHLPSP 1033 Score = 153 bits (372), Expect = 2e-35 Identities = 84/234 (35%), Positives = 127/234 (54%), Gaps = 10/234 (4%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 +SS E A+RL + +++ QL R YP RIDS+N NP+ FW G Q+VALN Sbjct: 1245 ISSVNENAAKRLCRRYSQKL-IQHTVCQLLRTYPAATRIDSTNPNPLLFWLHGIQLVALN 1303 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG---YNP-CDKKSIEGKVKPVTVMLRV 1080 YQT D PMQ+N F+ NGGCG++LKP +++ Y C + K+ P L + Sbjct: 1304 YQTDDLPMQLNTALFEANGGCGYVLKPAVLWDRNCPMYQQFCPMERDVEKMSPAVYSLAI 1363 Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140 + +++C G + SP +EV+++G DS TK + N LNP+WN+ +F V E+ Sbjct: 1364 VSGQNVC-PGNSSGSPCIEVDVLGMPVDS-AHFRTKPIHRNTLNPMWNEHFQFTVHFEEM 1421 Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194 +R V + + Q T PL L+ GYR + L +E LE+S+L ++ Sbjct: 1422 CFLRVAVVENN---SSQTTAQRTLPLKALKSGYRHIQLRTQHNESLEVSSLFIY 1472 >UniRef50_A3LSB2 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1; n=2; Saccharomycetaceae|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 - Pichia stipitis (Yeast) Length = 943 Score = 169 bits (410), Expect = 5e-40 Identities = 101/304 (33%), Positives = 161/304 (52%), Gaps = 32/304 (10%) Query: 159 SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVD--TEKRGEI-----GFDDFAVL 211 S ++ E ++ +++ + ++N I+ LR +F +V +K E+ FD F + Sbjct: 314 SDKSVREFLSFEDILKYSKRLNININRGYLRSIFDEVKKVNDKEDEVCGNGLNFDQFKLF 373 Query: 212 YQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYL 271 L DI + +S+ C +G ++TL F+ F+ Q D++ + + + + Sbjct: 374 VSTL----KKRSDIMEIWSLVCGSGQSMTLEIFKQFIIQVQKDSI--ENAVLHKIFKKFC 427 Query: 272 RDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGD 331 D Y+ F L SK ++ Q + Q M+ PLS Y+ISSSHNTYL G Sbjct: 428 VDTL-----DYWLPENFNNFLLSKYSTAIQ-QIEDEEQYMSYPLSEYYISSSHNTYLVGR 481 Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDGP------------DGTPFIYHGHTLTTKIRF 379 Q + +SS+E Y+R L+ GCRC+E+D WDG D P + HG T TT I F Sbjct: 482 QVAGDSSVEGYIRALQRGCRCVEVDVWDGEVAESEEGVQFQHDKEPIVNHGRTFTTAISF 541 Query: 380 MDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLP 439 +V+ TIK++AF TS YPL++S+E NCS+ QR++ ++ GD L+ P+ N T LP Sbjct: 542 SNVISTIKKYAFFTSPYPLVISLEINCSVASQRKIVDILKNTLGDTLIATPILDNAT-LP 600 Query: 440 SPHD 443 SP++ Sbjct: 601 SPNE 604 Score = 107 bits (256), Expect = 2e-21 Identities = 87/284 (30%), Positives = 137/284 (48%), Gaps = 23/284 (8%) Query: 930 RTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989 ++ +I E+SDL +Y + + F L + YN S E ++ + + H Sbjct: 662 KSTKIIDELSDLGVYFQGLKFRNFSLP-ESKTYNHCFSLSEKSINSMLKDETKKASIDKH 720 Query: 990 TTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFI 1048 + L R+YP R+ SSN+ P+ +W G QMVA N+QT D Q++ F G G++ Sbjct: 721 NRRYLMRVYPSKIRVRSSNFLPLKYWEHGVQMVATNWQTYDLGQQISEAMFDSVGRKGYV 780 Query: 1049 LKPQFMFEEGYNPCDKKSIEGKVKPVTVMLR----VIGARHLCKT-GRGTA-SPFVEVEI 1102 LK + + K+ K P T ++ +I A L K+ G A +PFV+ EI Sbjct: 781 LKDTSLRKPLLKSLRKQ--VSKYSPGTFEVKFDFEIISAHQLPKSKGEENAINPFVQFEI 838 Query: 1103 IGA---DYDSGVKLV--TKTVSDNGLNPLWNDICEFEV-ANPELALIRFVV-----QDED 1151 IGA ++D + TK VS+NG NP WN ++ A L ++F + + E+ Sbjct: 839 IGATTIEWDDNSMALGKTKIVSENGFNPRWNQTFSGKMTAANNLVFVKFTIFASESKTEE 898 Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 I P IG L L++GYR + + + F EEL S+L V + Sbjct: 899 IEASP--IGICVARLNNLKRGYRYLNVNDLFGEELVYSSLFVKI 940 >UniRef50_P13217 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase; n=12; Pancrustacea|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase - Drosophila melanogaster (Fruit fly) Length = 1095 Score = 169 bits (410), Expect = 5e-40 Identities = 120/405 (29%), Positives = 210/405 (51%), Gaps = 34/405 (8%) Query: 64 QGYEG-ALDIRDVKEVRTGKSSKDFERWPEETKRLESS------KCFTIYYGTEF-KLRC 115 +G +G +++ V ++R G + KD + + TK+ ++ + TI T++ + Sbjct: 58 EGRDGDVIELCQVSDIRAGGTPKDPKILDKVTKKNGTNIPELDKRSLTICSNTDYINITY 117 Query: 116 ASFVAQTDKECEAWVKGVLYLIAEAVSASYPLQI---ERWLRKEFYSIENSHEKITLKEV 172 + ++W K + + + + ++ + W+R Y +E S KI +K + Sbjct: 118 HHVICPDAATAKSWQKNLRLITHNNRATNVCPRVNLMKHWMRLS-YCVEKSG-KIPVKTL 175 Query: 173 -KAFLPKINCKISTSKLRDVFQDVD---TEKRGEIGFDDFAVLYQKLIFDENNVQDIFDK 228 K F K+ + ++D D T + + FD F LY K + N+++++F Sbjct: 176 AKTFASGKTEKLVYTCIKDAGLPDDKNATMTKEQFTFDKFYALYHK-VCPRNDIEELFT- 233 Query: 229 YSVYCSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYEP 281 S+ I+L +F F+ D+Q D + + +E + ++ I DY D ++ Sbjct: 234 -SITKGKQDFISLEQFIQFMNDKQRDPRMNEILYPLYEEKRCTEIINDYELDEEKK-KNV 291 Query: 282 YFTLSEFVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLE 340 +L F L S +N+ ++ + D +M +PL+HY+I+SSHNTYL+G Q +SS+E Sbjct: 292 QMSLDGFKRYLMSDENAPVFLDRLD-FYMEMDQPLAHYYINSSHNTYLSGRQIGGKSSVE 350 Query: 341 AYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 Y + L +GCRC+ELDCW+ G D P + HGH T+I F D ++ I + AF++SEYP+ Sbjct: 351 MYRQTLLAGCRCVELDCWNGKGEDEEPIVTHGHAYCTEILFKDCIQAIADCAFVSSEYPV 410 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKN--ETSLPSP 441 ILS E++C+ QQ ++A D FGDLLL P+ + + LP P Sbjct: 411 ILSFENHCNRAQQYKLAKYCDDFFGDLLLKEPLPDHPLDPGLPLP 455 Score = 165 bits (402), Expect = 5e-39 Identities = 101/265 (38%), Positives = 152/265 (57%), Gaps = 14/265 (5%) Query: 938 ISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIY 997 +S ++ Y + + F I+ + + MSSF E+ + +Q + FV Y+ Q+SRIY Sbjct: 550 LSSMVNYAQPIKFQGFDKAIEKNIAHNMSSFAESAGMNYL-KQSSIDFVNYNKRQMSRIY 608 Query: 998 PKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM--F 1055 PKG R DSSNY P FWN G QMV+LN+Q+ D PMQ+N GKF+ NGGCG++LKP FM Sbjct: 609 PKGTRADSSNYMPQVFWNAGCQMVSLNFQSSDLPMQLNQGKFEYNGGCGYLLKPDFMRRA 668 Query: 1056 EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK-LV 1114 ++ ++P ++G V ++VI + L GT +VEV++ G D+ K Sbjct: 669 DKDFDPFADAPVDG-VIAAQCSVKVIAGQFLSDKKVGT---YVEVDMFGLPSDTVKKEFR 724 Query: 1115 TKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172 T+ V++NGLNP++N D F +V P+LA++RF V +E +GQ PL L+ G Sbjct: 725 TRLVANNGLNPVYNEDPFVFRKVVLPDLAVLRFGVYEE----SGKILGQRILPLDGLQAG 780 Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197 YR V L + + L L V++ + Sbjct: 781 YRHVSLRTEANFPMSLPMLFVNIEL 805 >UniRef50_P25455 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase classes I and II; n=10; Endopterygota|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase classes I and II - Drosophila melanogaster (Fruit fly) Length = 1318 Score = 168 bits (409), Expect = 7e-40 Identities = 123/390 (31%), Positives = 199/390 (51%), Gaps = 33/390 (8%) Query: 70 LDIRDVKEVRTG---KSSKDFER------WPEETKRLESSKCFTIYYGTEF-KLRCASFV 119 LDI +++VRTG K KD + P++T LE K T+ +G++F + +F Sbjct: 62 LDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDT--LEE-KTVTVCHGSDFVNMTFVNFC 118 Query: 120 AQTDKECEAWVKGVL---YLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFL 176 + W G++ Y +A+ ++ S + +++ K ++ S +K F Sbjct: 119 CTRRDIAQLWTDGLIKLAYSLAQ-LNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFA 177 Query: 177 PKINCKISTSKLRDVFQ----DVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVY 232 + K DV VD+ + F+DF LY K + + V+ +FD V Sbjct: 178 QNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLY-KYLTQRSEVERLFDSI-VG 235 Query: 233 CSNGTTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQR-DIYEPYFT 284 S +++ + FL Q D L + + +A + I+ Y +P + + + + Sbjct: 236 NSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQY--EPNKFNAQKGQLS 293 Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344 L F+ L N I + DM +P+SHY+I+SSHNTYLTG Q + +SS+E Y + Sbjct: 294 LDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQ 353 Query: 345 CLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIED 404 CL +GCRC+ELD W+G P I HG+T +I DVL I E AF TSEYP+ILS E+ Sbjct: 354 CLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFEN 413 Query: 405 NCSLPQQRRMASAFQDVFGDLLLVHPMDKN 434 +C+ QQ ++A+ +++FGD+LL P+D + Sbjct: 414 HCNPRQQAKIANYCREIFGDMLLDKPLDSH 443 Score = 154 bits (374), Expect = 1e-35 Identities = 101/273 (36%), Positives = 150/273 (54%), Gaps = 16/273 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFN-IERLRIKGFVYNEMSSFPETKAERLMSQQENTFF 985 K ++ EIS L+ Y + + F+ E K Y EMSSF E +A L+ ++ F Sbjct: 588 KAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCY-EMSSFDEKQATTLLKERPIEF- 645 Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 V Y+ QLSR+YP G R DSSN+ P FWN G Q+VALN+QT D MQ+N+G F+ N Sbjct: 646 VNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARS 705 Query: 1046 GFILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEII 1103 G++LKP+FM + +P + +++G + TV + V+ + L A+ FVEV++ Sbjct: 706 GYLLKPEFMRRSDRRLDPFAESTVDGIIAG-TVSITVLSGQFLTDK---RANTFVEVDMY 761 Query: 1104 GADYDS-GVKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIG 1160 G D+ K TKTV DNG+NPL+++ +V PELA IR +E IG Sbjct: 762 GLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEG----GKLIG 817 Query: 1161 QATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 P++ L GYR V L + + + L++L + Sbjct: 818 HRVLPVIGLCPGYRHVNLRSEVGQPIALASLFL 850 >UniRef50_A4IGD0 Cluster: Plcb3 protein; n=11; Euteleostomi|Rep: Plcb3 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 557 Score = 168 bits (408), Expect = 9e-40 Identities = 127/430 (29%), Positives = 205/430 (47%), Gaps = 32/430 (7%) Query: 70 LDIRDVKEVRTGKSSKD--FERWPE-----ETKRLESSKCFTIYYGTEF-KLRCASFVAQ 121 LD+ +++ RTGK +K +R E + S+ T+ YG + + +F A Sbjct: 66 LDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFLNFQAV 125 Query: 122 TDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KAFLP 177 D C+ W + L +S + +L K + ++ KI +K + K F Sbjct: 126 QDGYCKLWTDELFKLATNMLSQN--ASRNTFLLKAYTKLKLQVTQDGKIPVKNILKMFSD 183 Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237 K +++ +F VD K + ++ F KL V+ IF + Sbjct: 184 KKRAEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLS-PRPEVERIF--VDLGSKGKP 240 Query: 238 TITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSEFVE 290 ++L + +F+ +Q D+ ++ + Q Q + Y + + + +L F + Sbjct: 241 FLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQ-LERDQISLMSFTK 299 Query: 291 MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGC 350 L ++N++ + + DM +PLSHY+I+SSHNTYLT Q + SS+E Y + L +GC Sbjct: 300 YLGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGC 359 Query: 351 RCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC-S 407 RCIELDCW G P+ P I HG T+TT+I F DV+ I E AF TS YPLILS E++ S Sbjct: 360 RCIELDCWKGRPPEEEPTITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDS 419 Query: 408 LPQQRRMASAFQDVFGDLLLVHPMDKNE----TSLPSPHDXXXXXXXXXXXXPEGAEESS 463 QQ +MA + +FGD LL+ P+DK LPSP + + Sbjct: 420 AKQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNG 479 Query: 464 FAVRQEEGKD 473 ++R+++G D Sbjct: 480 GSIRRKDGTD 489 >UniRef50_Q4S9T4 Cluster: Chromosome 2 SCAF14695, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2 SCAF14695, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1095 Score = 167 bits (406), Expect = 2e-39 Identities = 97/242 (40%), Positives = 139/242 (57%), Gaps = 9/242 (3%) Query: 962 YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021 Y + S E +A RL ++ V + L+R+ P R+DSSN NP +W G Q+V Sbjct: 630 YWTLCSLGEGEAGRLTTESPEDL-VTFTKRTLTRVRPSSVRLDSSNPNPQGYWKGGLQLV 688 Query: 1022 ALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE-GYNPCDKKSIEGKVKPVTVMLRV 1080 ALN QTP + +N G+F QNGGCG++L+P M +E Y + V P T+ ++V Sbjct: 689 ALNQQTPGAMLDINRGRFSQNGGCGYVLRPAVMRDEVSYFSAHTQGCVPGVPPQTLRIKV 748 Query: 1081 IGARHLCK-TGRG----TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEV 1135 I A L K G G P+V +E+ G D + T+T + N +PL+++ EF+V Sbjct: 749 ISAHSLPKPIGSGAKGEVIDPYVVLELHGVPADCAEQR-TRTAAQNQDDPLFDETFEFQV 807 Query: 1136 ANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 PELAL+RFVV D+D G+ +FIGQ T P CL+ GYRSVPL ++L S+L VH+ Sbjct: 808 NMPELALLRFVVLDDDYIGD-DFIGQYTVPFECLQPGYRSVPLLGMAGDQLPHSSLFVHV 866 Query: 1196 SI 1197 +I Sbjct: 867 AI 868 Score = 130 bits (315), Expect = 2e-28 Identities = 131/520 (25%), Positives = 218/520 (41%), Gaps = 64/520 (12%) Query: 2 KSVCFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINA 60 K+V F+ ++ + A +++++ G + K P R R + + + W Sbjct: 35 KTVSFSSMPSEKKVSSAADCLAFMQGGCELKKIRPNSRIYCRFYTLDPDLSCLRWE---P 91 Query: 61 PQRQGYEGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVA 120 ++ G LD+ V+EVRTGKS++ F +++L F+I +G +++ VA Sbjct: 92 SKKDGERARLDVSSVREVRTGKSTETFLHNGLPSEQLAEEAAFSIIHGDDYQ--SLDLVA 149 Query: 121 QTDKECEAWVKGVLYLIAE------------AVSASYPLQIER---------WLRKEFYS 159 + WV G+ YL+A S L +E WL EF Sbjct: 150 FSADVANIWVTGLRYLLAHPSIVGGGGGGGGVFSEGGGLVVEGSLGGKMRSDWLSAEFAQ 209 Query: 160 IENSHEKITLKEVKAF-LPKINCKISTSKLRDVFQDVDTEKR---GEIGFDDFAVLYQKL 215 ++ I ++V + K+ I +K+R F+++ K + ++F Y +L Sbjct: 210 VDEDGYGIVSEDVAVTTICKLCPGIKEAKVRLRFKEIQRSKEKLTSHVTCEEFQEAYCEL 269 Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275 D++ + + ++ + FL EQ +L E + +R Y +P Sbjct: 270 C----TRPDVYFLLVQLSKDRECLDPQDLRLFLETEQGLSLVTTE-GCLELLRRY--EPS 322 Query: 276 RDIYEP-YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334 E L L S + ++D ++ +V QDMT PLSHY+IS+S+ +YL DQ Sbjct: 323 AQAREKGLLGLDGLTRYLQSSECHLFDPEHLEVCQDMTMPLSHYYISTSYRSYLLDDQVH 382 Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFI-------------------YHGHTLTT 375 + ++ L+SGCRC+EL DGP+G P + +H H T Sbjct: 383 A-GRPRGLIKALQSGCRCVELGVTDGPEGEPLLGVDYGPDISRQHHHHHHHHHHHHHQHT 441 Query: 376 KIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL-----LVHP 430 I L I ++AF+TS+YPL+L + CS QQR MA + V G L L Sbjct: 442 PITIRSALEVINKYAFLTSQYPLLLYLCHRCSPAQQRTMAQHLKKVLGSRLYTPEALPVS 501 Query: 431 MDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEE 470 + T+LP+P E S V +EE Sbjct: 502 LGGRATTLPTPEQLRGRVLLVGKKLSPDQETSEGEVSEEE 541 >UniRef50_Q4RG56 Cluster: Chromosome 2 SCAF15106, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 2 SCAF15106, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1617 Score = 167 bits (405), Expect = 2e-39 Identities = 83/165 (50%), Positives = 105/165 (63%), Gaps = 5/165 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR-PLSHYWISSSHNTYLTGDQFSSESSLE 340 + + F L K N ++ Q+ R PLS+Y+I SSHNTYLTG Q ESS+E Sbjct: 804 WMSFEGFSRFLMDKDNFASCIDESQMNQEELRYPLSYYYIQSSHNTYLTGHQLKGESSVE 863 Query: 341 AYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLIL 400 Y + L GCR +ELDCWDG DG P IYHGHTLTTKI F DV+ I AF+ S P+IL Sbjct: 864 LYSQVLLQGCRSVELDCWDGDDGMPVIYHGHTLTTKIPFKDVVEAISRSAFVNSNMPVIL 923 Query: 401 SIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441 SIE++CSLPQQR+MA F+ VFG+ L+ + ++ S LPSP Sbjct: 924 SIENHCSLPQQRKMAEIFKTVFGERLVTRFLFDSDFSDDPHLPSP 968 Score = 151 bits (367), Expect = 9e-35 Identities = 84/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 +SS E A+RL + +++ QL R YP RIDS+N NP+ FW G Q+VALN Sbjct: 1214 ISSVNENAAKRLCRRYSQKL-IQHTACQLLRTYPAATRIDSTNPNPLLFWLHGIQLVALN 1272 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE---GYNP-CDKKSIEGKVKPVTVMLRV 1080 YQT D PMQ+N F+ NGGCG++LKP +++ Y C + K+ P + Sbjct: 1273 YQTDDLPMQLNTSLFEANGGCGYVLKPAVLWDRNCLNYQQFCPMERDVEKMSPAVYSFTI 1332 Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140 + +++C G + SP +EV+++G DS TK + N LNP+WN+ +F V E+ Sbjct: 1333 VSGQNVC-PGNSSGSPCIEVDVLGMSVDS-AHFRTKPIHRNTLNPMWNEHFQFTVHFEEM 1390 Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194 +R V + + Q T PL L+ GYR + L +E LE+S+L V+ Sbjct: 1391 CFLRVAVVENN---SSQTTAQRTLPLKALKSGYRHIQLRTQHNEFLEVSSLFVY 1441 >UniRef50_Q16ZC0 Cluster: Phospholipase c epsilon; n=1; Aedes aegypti|Rep: Phospholipase c epsilon - Aedes aegypti (Yellowfever mosquito) Length = 1022 Score = 167 bits (405), Expect = 2e-39 Identities = 81/158 (51%), Positives = 107/158 (67%), Gaps = 4/158 (2%) Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347 F + K N + S+ + M PLS Y+I+SSHNTYLTG Q ESS+E Y + L Sbjct: 19 FARYMMDKDNYAFLSELMPESTYMNLPLSQYYIASSHNTYLTGHQLKGESSVELYSQVLL 78 Query: 348 SGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407 +G RC+ELDCWDG DGTP IYHGHT TTKI F V+ I + AF+ S YP+ILSIE++CS Sbjct: 79 TGARCVELDCWDGDDGTPVIYHGHTFTTKIPFRAVVEAINKSAFVQSAYPVILSIENHCS 138 Query: 408 LPQQRRMASAFQDVFGDLLLVHPM-DKNETS---LPSP 441 + QQ+RMA+ FQ +FG+ L+ + + D++ T LPSP Sbjct: 139 VTQQQRMAAIFQAIFGEKLVTNFLFDQDYTDEPYLPSP 176 Score = 142 bits (344), Expect = 5e-32 Identities = 81/236 (34%), Positives = 129/236 (54%), Gaps = 15/236 (6%) Query: 964 EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023 + SS E A++L +++ + + TQL R YP G RIDSSN+NPV FW+ G QMVAL Sbjct: 406 QCSSLNEASAKKLC-RKDPLGLIAHTETQLMRTYPAGLRIDSSNFNPVFFWSFGFQMVAL 464 Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG------YNPCDKKSIEGKVKPVTVM 1077 NYQT D PM +N F++N CG++ KP ++ +NP +K+ +G + ++ Sbjct: 465 NYQTEDMPMHINKAMFEENNSCGYVRKPDVLWNRSHLMYRRFNPLEKE-FDG-LHVTQLV 522 Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137 + V+ ++L G VE+E++G D G + TK V N NP+WN+ F++ Sbjct: 523 INVVSGQYLNHVTGGNVI-HVEIELLGIPIDCG-RRRTKPVKHNLFNPVWNETFFFKIMF 580 Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 +LA ++F V + E + Q L C R GYR V L + ++ L +++L + Sbjct: 581 HDLAFLKFTVYE----SESVVVAQRVISLKCFRPGYRHVRLRSPINQPLNMASLFL 632 >UniRef50_Q9P212 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1; n=28; Amniota|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 - Homo sapiens (Human) Length = 2302 Score = 167 bits (405), Expect = 2e-39 Identities = 82/160 (51%), Positives = 107/160 (66%), Gaps = 7/160 (4%) Query: 288 FVEMLYSKQN--SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345 F L K+N S D + + +++ PLS+Y+I SSHNTYLTG Q ESS+E Y + Sbjct: 1370 FARFLMDKENFASKNDESQENI-KELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQV 1428 Query: 346 LRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405 L GCR +ELDCWDG DG P IYHGHTLTTKI F +V+ I AFI S+ P+I+SIE++ Sbjct: 1429 LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH 1488 Query: 406 CSLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSP 441 CSLPQQR+MA F+ VFG+ L+ + + + S LPSP Sbjct: 1489 CSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSP 1528 Score = 145 bits (351), Expect = 7e-33 Identities = 83/234 (35%), Positives = 126/234 (53%), Gaps = 10/234 (4%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 +SS E A+RL + ++ QL R YP RIDSSN NP+ FW G Q+VALN Sbjct: 1757 ISSLNENAAKRLCRRYSQKL-TQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALN 1815 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS-IE---GKVKPVTVMLRV 1080 YQT D P+ +N F+ NGGCG++LKP ++++ K S +E + P L + Sbjct: 1816 YQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTI 1875 Query: 1081 IGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140 + +++C + SP +EV+++G DS TK + N LNP+WN+ F V +L Sbjct: 1876 VSGQNVCPS-NSMGSPCIEVDVLGMPLDS-CHFRTKPIHRNTLNPMWNEQFLFHVHFEDL 1933 Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVH 1194 +RF V + + Q PL L++GYR + L N +E LE+S+L ++ Sbjct: 1934 VFLRFAVVENN---SSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFIN 1984 >UniRef50_A7S279 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1125 Score = 165 bits (402), Expect = 5e-39 Identities = 119/398 (29%), Positives = 193/398 (48%), Gaps = 32/398 (8%) Query: 69 ALDIRDVKEVRTGKSSKDFERWPEETKRLESS----KCFTIYYGTEF-KLRCASFVAQTD 123 +++I ++ EVR G KD ++ E +R + + FT+ Y T A T Sbjct: 65 SIEISNISEVRLGVLPKD-QKVRESLQRTGADPLEERGFTVVYNTNLVDCNYLHLFASTS 123 Query: 124 KECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIENSHEKITLKEVKAFLPKINCKI 183 + + WV+G+ L+ + + + L K++ + + VK+ + Sbjct: 124 RVAKEWVEGLRPLLHNVRLDNCSVLTQ--LHKQYVKAGLHKDALGKISVKSICKALYAGK 181 Query: 184 STSKLRDVFQDV-------DTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNG 236 S + D Q + D + F+ F LY K + + ++ ++ Sbjct: 182 FESLVLDALQALGLPCSKNDKITPEDFTFEHFYQLYLK-VCPRLEIMELCVEWGG--GRA 238 Query: 237 TTITLREFQNFLRDEQHD-NLGD------DEVQASQFIRDYLRDPQRDIYE-PYFTLSEF 288 +T + NF+ EQ D L + D +A I Y + Q D+ + ++ Sbjct: 239 PILTATQLVNFMNKEQRDPRLNEILFPFCDNEKALSLIWKY--EKQMDMLQRDRICVNGL 296 Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348 L S+ N + ++ DM +PLSHY+I+SSHNTYL G QF SS+E Y +CL + Sbjct: 297 TRYLLSEDNLLIMPGRLNLSDDMNQPLSHYFINSSHNTYLVGRQFGGRSSVEMYRQCLIA 356 Query: 349 GCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSL 408 GCRCIELDCWDG + P I HG+ + TKI F DV+ I++ AF TS++P+ILS E++CS Sbjct: 357 GCRCIELDCWDGQNDEPIITHGNAMCTKILFKDVIEAIRDSAFQTSDFPVILSFENHCSK 416 Query: 409 PQQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPH 442 QQ +MA D+ GD+L+ P++ + LPSP+ Sbjct: 417 HQQYKMACYCMDILGDMLVTKPLESCPLEEGRPLPSPN 454 Score = 160 bits (388), Expect = 2e-37 Identities = 104/272 (38%), Positives = 150/272 (55%), Gaps = 14/272 (5%) Query: 931 TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990 T I +S L+ Y + V F K ++ +MSSF E+ L+ + FVKY+ Sbjct: 559 TGNINPLLSSLVNYIQPVPFQGFDESEKRNLFYQMSSFNESTGFGLV-RATPLDFVKYNK 617 Query: 991 TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050 Q+SRIYP+G R+DSSNY P FWN G QMV+LN+QTPD P +N GKF+ NG G+ILK Sbjct: 618 RQMSRIYPRGSRVDSSNYMPQVFWNVGCQMVSLNFQTPDLPFHLNQGKFEFNGRSGYILK 677 Query: 1051 PQFMFEEG--YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108 P M + ++P + I+G V V ++VI ++L T VEV++ G D Sbjct: 678 PDLMRRDDRMFDPFTESPIDGYV-GAYVAIKVISGQYLSDKKITTV---VEVDMYGLPTD 733 Query: 1109 S-GVKLVTKTVSDNGLNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 + K TK+ + NGLN L++ + V PE+AL+RF V D++ I Q P Sbjct: 734 TIRKKYKTKSSTSNGLNTLYDGEHMVFRRVVLPEMALLRFAVIDDN----DRIIAQRVVP 789 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L ++ GYR VPL + L+TL VH+++ Sbjct: 790 LDSIQAGYRHVPLRTENDTPIPLATLFVHITL 821 >UniRef50_Q4FXB0 Cluster: Phosphatidylinositol-specific phospholipase-like protein; n=3; Leishmania|Rep: Phosphatidylinositol-specific phospholipase-like protein - Leishmania major strain Friedlin Length = 729 Score = 165 bits (400), Expect = 9e-39 Identities = 100/289 (34%), Positives = 153/289 (52%), Gaps = 23/289 (7%) Query: 157 FYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLI 216 F + + K++ E+ K+ ++ ++L D F+ D++K + + +F ++ Sbjct: 150 FIAAQQGKTKLSFTEISMLTNKLFGRVPAAELADRFRQCDSDKDTCLNYQEFCEFFR--Y 207 Query: 217 FDENN-VQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275 F+E V+ I+++++ C+ G +T EF F AS F R Sbjct: 208 FNEAKAVRSIYERHTSECAPG--MTAEEFTRFCISNDAAATVTPMRCASLFHLFANRQSD 265 Query: 276 RDIYEPYFTLSEFVE-MLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFS 334 R LS F +L+ NSI D++ ++T M PL HY+I+SSHNTYLTG+Q + Sbjct: 266 R------MALSGFTAFLLHPHHNSIVDARQLRLTDSMDHPLPHYFINSSHNTYLTGNQLN 319 Query: 335 SESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFIT- 393 SESS Y L +GCRC+E+DCWDGP G P +YHGHT+TTKI F DV+RTI ++AF Sbjct: 320 SESSCNMYRDVLLAGCRCVEIDCWDGPAGVPVVYHGHTMTTKIAFDDVVRTINDYAFQNP 379 Query: 394 ----------SEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMD 432 E P+I+S+E + S Q RMA + VF + L + +D Sbjct: 380 SNNQEAAWNPRELPVIVSLEVHTSPEQTNRMAEIIRSVFKERLFLSRLD 428 Score = 112 bits (269), Expect = 6e-23 Identities = 74/218 (33%), Positives = 110/218 (50%), Gaps = 15/218 (6%) Query: 985 FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKF-KQNG 1043 F + +T LSRIYP G RIDSSNY+P+ W G Q+VALN+QT D +VN G F QNG Sbjct: 519 FARQNTHMLSRIYPSGTRIDSSNYDPMLMWRLGCQLVALNWQTRDHNFRVNEGFFTHQNG 578 Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEI- 1102 GCG++LKP ++ + C P T+ LR+I HL T G + V + + Sbjct: 579 GCGYVLKPMYLRDVDAG-C-------SAVPFTLALRLICGSHLSTTFDGADATHVTLRLR 630 Query: 1103 IGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 + + S + T + P WN+ E + E A++ V G + + A Sbjct: 631 VHGEAWSHETIAVPTT----IYPEWNESMELQGKCKETAVLCLCVVAHTRSGATHDVCTA 686 Query: 1163 TFPLLCLRKGYRSVPLTNAFS-EELELSTLMVHLSIIT 1199 P+ LR GY ++PL + S E+++++ H S T Sbjct: 687 CLPVRVLRTGYHAMPLRHVKSGRTAEVASVLCHFSFKT 724 >UniRef50_Q9NQ66 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1; n=116; Eumetazoa|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 - Homo sapiens (Human) Length = 1216 Score = 165 bits (400), Expect = 9e-39 Identities = 104/270 (38%), Positives = 154/270 (57%), Gaps = 20/270 (7%) Query: 936 KEISDLIIYCRSV---TFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +E+S+L+ Y + V +F I + R K F EMSSF ETK +++ FV+Y+ Q Sbjct: 538 EEMSNLVNYIQPVKFESFEISKKRNKSF---EMSSFVETKGLEQLTKSP-VEFVEYNKMQ 593 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 LSRIYPKG R+DSSNY P FWN G QMVALN+QT D MQ+NMG ++ NG G+ LKP+ Sbjct: 594 LSRIYPKGTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPE 653 Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110 FM ++ ++P + ++G V T+ +++I + L GT +VEV++ G D+ Sbjct: 654 FMRRPDKHFDPFTEGIVDGIVAN-TLSVKIISGQFLSDKKVGT---YVEVDMFGLPVDTR 709 Query: 1111 VK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167 K TKT N +NP+W + I +V P LA +R V +E FIG P+ Sbjct: 710 RKAFKTKTSQGNAVNPVWEEEPIVFKKVVLPTLACLRIAVYEEG----GKFIGHRILPVQ 765 Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 +R GY + L N ++ L L + V++ + Sbjct: 766 AIRPGYHYICLRNERNQPLTLPAVFVYIEV 795 Score = 147 bits (355), Expect = 2e-33 Identities = 73/163 (44%), Positives = 105/163 (64%), Gaps = 7/163 (4%) Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347 F+ L ++N + + + +DM++PLSHY+I+SSHNTYLT Q + SS+E Y + L Sbjct: 295 FMRYLSGEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLL 354 Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405 SGCRC+ELDCW G + P I HG T+TT+I F +V+ I E AF TS +P++LS E++ Sbjct: 355 SGCRCVELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENH 414 Query: 406 CSLP-QQRRMASAFQDVFGDLLLVHPMDK----NETSLPSPHD 443 P QQ +MA + +FGD LL+ P++K + LPSP D Sbjct: 415 VDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMD 457 >UniRef50_Q9TVI2 Cluster: Putative uncharacterized protein plc-1; n=4; Caenorhabditis|Rep: Putative uncharacterized protein plc-1 - Caenorhabditis elegans Length = 1898 Score = 164 bits (398), Expect = 1e-38 Identities = 73/119 (61%), Positives = 90/119 (75%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 +D+ PLSHY+I+SSHNTYLTG Q SS E Y + L +GCRC+ELDCWDG DG P IY Sbjct: 910 EDLRYPLSHYYINSSHNTYLTGHQLKGPSSSEMYRQVLLTGCRCVELDCWDGDDGLPLIY 969 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLL 427 HGHTL +KI F V+ IK+ AFITS+ P+ILSIE++CSL QQ +MA F+ V GDLL+ Sbjct: 970 HGHTLVSKIGFRQVVEIIKKSAFITSDLPVILSIENHCSLQQQAKMAQMFKTVLGDLLV 1028 Score = 132 bits (320), Expect = 4e-29 Identities = 78/220 (35%), Positives = 118/220 (53%), Gaps = 11/220 (5%) Query: 964 EMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVAL 1023 +++S E A++LM + V Y L R YP + DSSN+NP+ W G QMVAL Sbjct: 1296 QVTSLNENAAKKLMKRHPAKC-VSYTRDHLIRTYPSAKHYDSSNFNPINCWAHGMQMVAL 1354 Query: 1024 NYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDK-----KSIEGKVKPVTVML 1078 N+QTPD M VN F+Q+G CG+ LKP+ +++E + +K K I G + + L Sbjct: 1355 NFQTPDVIMAVNQAMFEQSGNCGYQLKPRCLWDESHLLYNKFLPLSKDIAGH-SALLLNL 1413 Query: 1079 RVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANP 1138 +I +H+ AS +VE+E+IG D V+ +K V N +NP+WN + +A Sbjct: 1414 TIISGQHVYPNTH-YASLYVEIEVIGIHNDC-VREKSKVVQRNSVNPIWNHTTQLRIACV 1471 Query: 1139 ELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 +LA +R V D G + P+ C+R G+R +PL Sbjct: 1472 DLAFLRIAVCDSGQNG--RVVAHRVVPVKCIRPGFRHLPL 1509 >UniRef50_Q4Q6Z7 Cluster: Phospholipase c-like protein; n=2; Leishmania|Rep: Phospholipase c-like protein - Leishmania major Length = 560 Score = 163 bits (395), Expect = 3e-38 Identities = 97/252 (38%), Positives = 141/252 (55%), Gaps = 18/252 (7%) Query: 178 KINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGT 237 ++N +IS L D+ + D G + +F L+ +L E ++ +F ++ Sbjct: 4 RMNVEISDDLLADLVRKHDASGDGALDLKEFTTLFIQLTQHEE-LRPLFASFAAQVD--- 59 Query: 238 TITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSK-Q 296 +T EF FL+ + GD +S + + L+ P ++ T ++FV L S Sbjct: 60 WMTRAEFDCFLKAQ-----GD---VSSDVLFNTLK-PDKN---GRITFTQFVHYLLSPCL 107 Query: 297 NSIYDSQYDK-VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355 N D + V +MT PL Y+I+SSHNTYL+GDQF S S +E Y R L +GCRC+EL Sbjct: 108 NPALDPAHQTGVVDEMTHPLKDYFINSSHNTYLSGDQFQSSSRIEMYRRALLAGCRCVEL 167 Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415 DCWDG D P IYHGHT T+KIRF DV+ TI+ HAF S +P+ILS+E + S Q MA Sbjct: 168 DCWDGKDNDPVIYHGHTRTSKIRFADVIETIRRHAFTASPFPVILSLEVHTSDEQSMVMA 227 Query: 416 SAFQDVFGDLLL 427 + + GD+L+ Sbjct: 228 GHLRTILGDMLM 239 Score = 128 bits (309), Expect = 9e-28 Identities = 76/218 (34%), Positives = 113/218 (51%), Gaps = 16/218 (7%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 + S+ ET + L + F + + L R+YPKG RI SSNYNP W+ G+Q+VALN Sbjct: 328 IQSYVETVVKELALGHRDEF-IGQTSRMLVRVYPKGTRIGSSNYNPTTAWSVGAQLVALN 386 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084 YQT D M++N G F N GCG++LKP ++ NP K K P T+ + V+ Sbjct: 387 YQTWDDDMRLNDGMFSLNKGCGYVLKPDYL----RNPSGK----AKATPCTITVTVLSGT 438 Query: 1085 HLCKTG---RG-TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPEL 1140 + K +G P+V++ I D ++ T V +NGLNP W + + E+ Sbjct: 439 QIPKPSLQKKGDITDPYVKLYINKRD---RTEVKTSVVRNNGLNPYWMETFTLACESKEI 495 Query: 1141 ALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 L+ V DED + + + P+ LR GYR+VP+ Sbjct: 496 GLLTVKVMDEDTTSANDSVCEMVIPVRALRTGYRAVPM 533 >UniRef50_Q95X29 Cluster: Egg laying defective protein 8, isoform b; n=5; Caenorhabditis|Rep: Egg laying defective protein 8, isoform b - Caenorhabditis elegans Length = 1431 Score = 160 bits (389), Expect = 2e-37 Identities = 110/275 (40%), Positives = 154/275 (56%), Gaps = 15/275 (5%) Query: 931 TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHT 990 T I +S L+ Y V F+ + ++ MSSF E+ + Q F V Y+ Sbjct: 751 TTNIHPLLSSLVNYTHPVKFSGFDVAEANNLHFHMSSFSESTGLGYLKQSAPEF-VNYNK 809 Query: 991 TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050 Q SRIYPKG R+DSSN+ P FWN G QMV+LN+QTPD MQ+NMGKF+ NGG G++LK Sbjct: 810 RQSSRIYPKGARVDSSNFLPQIFWNAGCQMVSLNFQTPDVYMQLNMGKFEYNGGSGYLLK 869 Query: 1051 PQFMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYD 1108 P F+ + ++P + ++G V +RVI + L GT +VEVE+ G D Sbjct: 870 PDFLRRPDRTFDPFSESPVDG-VIAAHCSVRVISGQFLSDRKIGT---YVEVEMYGLPTD 925 Query: 1109 SGVK-LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 + K TK + NGLNP++N D F +V PELA++RF V DE+ G+ +GQ P Sbjct: 926 TIRKEHKTKVIPGNGLNPVYNEDPFVFRKVVLPELAVLRFAVYDEN--GKQ--LGQRILP 981 Query: 1166 LLCLRKGYRSVPLTNAFSEELELS-TLMVHLSIIT 1199 L L+ GYR + L + ++ LS L V + I T Sbjct: 982 LDGLQAGYRHISLRSDTNQSFILSPVLFVQIVIKT 1016 Score = 158 bits (383), Expect = 1e-36 Identities = 104/274 (37%), Positives = 147/274 (53%), Gaps = 20/274 (7%) Query: 182 KISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITL 241 K S + R +++D + + F+ F LY K I VQ++F K S +T Sbjct: 214 KCSRGRKRKEREELDVDI---LTFEKFQRLYNK-ICPRTEVQELFVKLS---GQKEYLTK 266 Query: 242 REFQNFLRDEQHDNLGDDEVQA---SQFIRDYLRDPQRDI-YEPYFTLSE--FVEMLYSK 295 NFL +EQ D ++ + SQ I L+ + DI Y+ +S F+ L S Sbjct: 267 ERLINFLNEEQRDPRLNEILFPFFDSQRIVALLKKHENDIKYQEDGKMSGDGFLRFLMSD 326 Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355 +N ++ DM +PL HY+I+SSHNTYLTG Q+ +SS E Y + L SGCRCIEL Sbjct: 327 ENPPVFLDRIEMFMDMDQPLCHYYINSSHNTYLTGRQYGGKSSSEIYRQVLLSGCRCIEL 386 Query: 356 DCWDGP---DGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQR 412 DCWDG G P I HG + T + F DVL I++ AF S++P++LS E++CS Q Sbjct: 387 DCWDGTGENKGEPIITHGKAMCTDVFFKDVLVQIRDTAFARSDFPVVLSFENHCSKSNQL 446 Query: 413 RMASAFQDVFGDLLLVHPMDKNE----TSLPSPH 442 +MA D+FGD+LL P + SLPSP+ Sbjct: 447 KMAKYCMDIFGDMLLSKPFEDAPLDPGVSLPSPN 480 >UniRef50_A0C336 Cluster: Chromosome undetermined scaffold_146, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_146, whole genome shotgun sequence - Paramecium tetraurelia Length = 709 Score = 160 bits (388), Expect = 2e-37 Identities = 103/303 (33%), Positives = 163/303 (53%), Gaps = 24/303 (7%) Query: 131 KGVLYLIAEAVSASYPLQI--ERW---LRKEFYSIENSHEKITLKEVKAFLPKINCKIST 185 +G+ YL+AEA L + W L+ S + +++ KE + + ++ +I Sbjct: 97 EGLQYLMAEAFRIQKQLDSYNQIWSNALKLITKSDLDMDNRLSFKEFQFLIGELQIEIPE 156 Query: 186 SKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQ 245 KL +F +K ++ D A LY KL+ + ++ Y YCS I + Sbjct: 157 RKLLQLFDK--HQKNNQL---DEATLY-KLLMEITRKHELIQLYQKYCSKQEGI-FDDPH 209 Query: 246 NFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYD 305 N + HD ++ Q +DY Q+ Y Y +F ++++++NSI+ ++ Sbjct: 210 NTMLMSAHDLETFFLIEQGQ--KDY--KAQKQCYNFY----DFQNIIFNQENSIFQAK-- 259 Query: 306 KVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365 D ++PL+ Y I+SSHNTYL +Q + +SS AY + G +C+ELDCWDG DG P Sbjct: 260 --DFDKSQPLTQYLINSSHNTYLETNQLTGQSSCFAYQDAFKMGFKCVELDCWDGQDGEP 317 Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425 + HGHTL I+F+DV+RT++E AFI + P ILS+E +CSL QQRR+A + V GD+ Sbjct: 318 NVTHGHTLVNDIKFIDVIRTVREFAFIKDDNPAILSLEMHCSLKQQRRIADIIRSVLGDM 377 Query: 426 LLV 428 L V Sbjct: 378 LFV 380 Score = 104 bits (250), Expect = 1e-20 Identities = 74/240 (30%), Positives = 123/240 (51%), Gaps = 29/240 (12%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 +SS E K + ++ + + F Y T RIYP G R DSSNY+P P W+ G+QMVALN Sbjct: 490 VSSVSEDKIQDVVKKNQGKF-QDYVNTYFVRIYPLGLRFDSSNYDPFPSWSAGAQMVALN 548 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084 QT D M N G F + ++LK K I+ +T+ +++I A Sbjct: 549 IQTKDIFMLYNYGMFLNS---SYVLK------------SKNDIQ-----MTIFIQIISAS 588 Query: 1085 HLC-----KTGRGTASPFVEVEIIG--ADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137 ++ + + P+++V I G D ++ K T+ + DNG +P++N C+ ++ + Sbjct: 589 NIVWEEEKRRQQEVVDPYIKVRIAGNKEDVNNSEKWRTEVIYDNGYHPIFNYKCKIQLKH 648 Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 + +I F + G+ + +GQ L LR+GYR VPL N+ + L S ++V++ I Sbjct: 649 AQQDVIYFQAYSYSLLGD-SLLGQYCLSPLNLRRGYRIVPLLNSQLKPLLNSFVLVNIKI 707 >UniRef50_A0CKY8 Cluster: Chromosome undetermined scaffold_20, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_20, whole genome shotgun sequence - Paramecium tetraurelia Length = 773 Score = 156 bits (379), Expect = 3e-36 Identities = 79/183 (43%), Positives = 115/183 (62%), Gaps = 7/183 (3%) Query: 260 EVQASQFIRDYLRDPQRDIYEPY-FTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHY 318 E +FIR R D + + T +F + L+S+QNSI++ + + DMT+PLSHY Sbjct: 222 EADFEKFIRTAQRQQDTDYFFGFPMTADKFNDFLFSQQNSIFEMGH---SDDMTKPLSHY 278 Query: 319 WISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGTPFIYHGHTLTTKI 377 +I+SSHNTYLT DQ + +SS+ YV L +GCRC ELDCWD D P +YHG+TLT+KI Sbjct: 279 YINSSHNTYLTKDQLAGDSSVGQYVIALLNGCRCFELDCWDSISDRNPVVYHGYTLTSKI 338 Query: 378 RFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS 437 F D + + + F+ S YP+ILS+E +CS+ QQ + + F D L ++ ++N + Sbjct: 339 LFEDAILALDKFGFMFSSYPIILSLELHCSIDQQEVLGQIMRAQFKDELYIY--EQNLSV 396 Query: 438 LPS 440 LPS Sbjct: 397 LPS 399 Score = 126 bits (303), Expect = 5e-27 Identities = 75/244 (30%), Positives = 134/244 (54%), Gaps = 7/244 (2%) Query: 958 KGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCG 1017 K ++N +SS E K +++ +++ ++ L RIYP G R+DSSN++P+P + G Sbjct: 532 KRSIWN-ISSLSEDKVDKIFKEKKVKEVQQHLNNYLVRIYPSGMRVDSSNFDPIPSFILG 590 Query: 1018 SQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVM 1077 +Q++ALN+QT D+PM +N +F QN G G++LKP+++ E + +S + K VT Sbjct: 591 AQIIALNFQTKDEPMLINRARFSQNLGIGYVLKPKYLIEGLDQVTNFESPDYPKKLVT-- 648 Query: 1078 LRVIGARHLCKTGRGTASPFVEVEIIGADYD-SGVKLVTKTVSDNGLNPLWN---DICEF 1133 L +I + + +P V V++ G D +G +L T + +NGLNP ++ F Sbjct: 649 LEIISCQLFLLHTKNVINPQVIVKLKGNKVDENGQELQTNVIYNNGLNPEFDQNYSKTTF 708 Query: 1134 EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 EV + + A+ F V ++ + IGQ P +R+G+R++PL + +E + Sbjct: 709 EVKDVDQAIFIFKVFNKSDDNKQTIIGQYALPFKNMREGFRAIPLKDENLMVMEYCYIFA 768 Query: 1194 HLSI 1197 ++I Sbjct: 769 QVTI 772 >UniRef50_Q4TBY5 Cluster: Chromosome undetermined SCAF7071, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF7071, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1237 Score = 156 bits (378), Expect = 4e-36 Identities = 121/403 (30%), Positives = 193/403 (47%), Gaps = 39/403 (9%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLE----------SSKCFTIYYGTEF-KLRCASF 118 LD+ +++ RTGK +K P++ + E K TI +G++ + +F Sbjct: 6 LDMSTIRDTRTGKYAKQ----PKDVRVREVLGFGKGESVERKLVTIVHGSDLVNISFLNF 61 Query: 119 VAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEV-KA 174 A + + W + L +S + +L K F ++ N KI +K V K Sbjct: 62 QAMQEDTAKIWTDELFTLATNILSQN--ASRNTFLLKAFTKLKLQVNQDGKIPVKNVLKL 119 Query: 175 FLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCS 234 F K + + + V + K + ++ F L +Q IF++ Sbjct: 120 FSDKKRVETALEQCGLVNNRSEGLKPDDFTWEAFQNFLNSLCL-RPEIQSIFEESG--SK 176 Query: 235 NGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYEPYFTLSE 287 I+L +F +F+ Q D+ ++ + Q Q + Y + + + +L Sbjct: 177 RKPFISLDQFMDFINRRQRDSRLNEVLYPPLKREQVRQIMERYESNTSQ-LERDQISLQA 235 Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347 F L ++N I + V DM +PLSHY+I+SSHNTYLT Q + SS+E Y + L Sbjct: 236 FARYLGGEENGIVPPERLDVIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLL 295 Query: 348 SGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDN 405 +GCRC+ELDCW G D P+I HG T+TT+I F +V+ I E AF TS YP+ILS E++ Sbjct: 296 TGCRCVELDCWKGRPHDEEPYITHGFTMTTEIPFKEVIEAIAESAFKTSPYPVILSFENH 355 Query: 406 C-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443 S QQ +MA + +FGD L++ P++K LPSP + Sbjct: 356 VDSAKQQAKMAEYCRTIFGDALVIDPLEKYPLEPGQPLPSPQE 398 Score = 126 bits (304), Expect = 4e-27 Identities = 89/249 (35%), Positives = 129/249 (51%), Gaps = 47/249 (18%) Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +Y+ QLSRIYPKG R+DSSNY P FWN G QMVALN+QT D PMQ+NMG F+ NGG G Sbjct: 594 RYNKNQLSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLDLPMQLNMGVFEYNGGSG 653 Query: 1047 FILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGT----------- 1093 ++LKP+FM ++ ++P + ++G V TV ++V G C T Sbjct: 654 YLLKPEFMRRTDKHFDPFTENIVDGIVAN-TVKIKV-GPSFWCPVAAPTTHQVISGQFLT 711 Query: 1094 ---ASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWND--ICEFEVANPE--------- 1139 +VEV++ G D+ K TKT + N L+P+W+D +V PE Sbjct: 712 DKKVGVYVEVDMFGLPADTKRKYRTKTSNGNSLDPVWDDDMFVFTKVGVPEPRPPRLTVP 771 Query: 1140 --------------LALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185 LA +R VV +E+ F+G P+ +R G+ + L N ++ Sbjct: 772 YPPSPPSPQVVLPTLASLRIVVFEEN----GKFVGHRILPVSAIRPGFHYINLKNELNQP 827 Query: 1186 LELSTLMVH 1194 L L +L+V+ Sbjct: 828 LLLPSLLVY 836 >UniRef50_Q01970 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; n=27; Tetrapoda|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 - Homo sapiens (Human) Length = 1234 Score = 156 bits (378), Expect = 4e-36 Identities = 99/264 (37%), Positives = 149/264 (56%), Gaps = 15/264 (5%) Query: 936 KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994 +E+S L+ Y V F + E R + + EMSSF ETKA +++ F V+Y+ QLS Sbjct: 588 EEMSTLVNYIEPVKFKSFEAARKRNKCF-EMSSFVETKAMEQLTKSPMEF-VEYNKQQLS 645 Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054 RIYPKG R+DSSNY P FWN G Q+VALN+QT D MQ+N G F+ NG G++LKP+FM Sbjct: 646 RIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKPEFM 705 Query: 1055 F--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112 ++ ++P + ++G V + ++VI + L G +VEV++ G D+ K Sbjct: 706 RRPDKSFDPFTEVIVDGIVAN-ALRVKVISGQFLSDRKVGI---YVEVDMFGLPVDTRRK 761 Query: 1113 LVTKTVSDNGLNPLWN-DICEF-EVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLR 1170 T+T N NP+W+ + +F +V P LA +R +E F+G P+ +R Sbjct: 762 YRTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEG----GKFVGHRILPVSAIR 817 Query: 1171 KGYRSVPLTNAFSEELELSTLMVH 1194 GY V L N ++ L L L+++ Sbjct: 818 SGYHYVCLRNEANQPLCLPALLIY 841 Score = 150 bits (363), Expect = 3e-34 Identities = 123/407 (30%), Positives = 198/407 (48%), Gaps = 45/407 (11%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETK------------RLESSKCFTIYYGTE-FKLRCA 116 LDI +++ RTG+ + R P++ K RLE K T+ G + Sbjct: 64 LDISSIRDTRTGR----YARLPKDPKIREVLGFGGPDARLEE-KLMTVVSGPDPVNTVFL 118 Query: 117 SFVAQTDKECEAWVKGVLYLIAEAVSASYPLQIERWLRKEFYSIE---NSHEKITLKEVK 173 +F+A D + W + L+ +A + A + +LRK + ++ N +I +K + Sbjct: 119 NFMAVQDDTAKVWSEE-LFKLAMNILAQNASR-NTFLRKAYTKLKLQVNQDGRIPVKNIL 176 Query: 174 AFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKY--SV 231 ++ T+ L + + I D+F++ + ++ ++ DK + Sbjct: 177 KMFSADKKRVETA-LESC--GLKFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEI 233 Query: 232 YCSNGTTITLREFQNFLRDEQHDNLGDDEV-------QASQFIRDYLRDPQRDIYE-PYF 283 +TL + +F+ +Q D ++ + QA I Y +P + E Sbjct: 234 GAKGKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRPSQARLLIEKY--EPNQQFLERDQM 291 Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 ++ F L ++N I + ++ DMT+PLS Y+I+SSHNTYLT Q + SS+E Y Sbjct: 292 SMEGFSRYLGGEENGILPLEALDLSTDMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYR 351 Query: 344 RCLRSGCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401 + L GCRC+ELD W G P+ PFI HG T+TT++ DVL I E AF TS YP+ILS Sbjct: 352 QALLWGCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILS 411 Query: 402 IEDNC-SLPQQRRMASAFQDVFGDLLLVHPMDKNETS----LPSPHD 443 E++ S QQ +MA + +FGD LL+ P+DK + LPSP D Sbjct: 412 FENHVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPGVPLPSPQD 458 >UniRef50_Q6CD33 Cluster: Similar to DEHA0A04554g Debaryomyces hansenii IPF 6581.1; n=1; Yarrowia lipolytica|Rep: Similar to DEHA0A04554g Debaryomyces hansenii IPF 6581.1 - Yarrowia lipolytica (Candida lipolytica) Length = 955 Score = 155 bits (377), Expect = 5e-36 Identities = 106/360 (29%), Positives = 174/360 (48%), Gaps = 29/360 (8%) Query: 100 SKCFTIYYGTEFKLRCASFVAQTDKECEAWV---KGVLYLIAEAV----SASYPLQIERW 152 S+ TI Y + + VA T +E +V + ++Y E + S++ + W Sbjct: 291 SRWVTITYMKNKRRKPLHLVAPTKEEFTLFVDALQNLVYFRQELMRGFQSSNPKIASVHW 350 Query: 153 LRKEFYSIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLY 212 K + + E E++T + V+ + + S + L+ F + D +K G + F++F + + Sbjct: 351 --KSYAAKEQGEERLTFEAVQRLAQRHHVLCSKAYLKSKFDEADVDKSGFLEFNEFKI-F 407 Query: 213 QKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLR 272 KL+ +I Y + RD+ L D VQ ++F Sbjct: 408 VKLL---KRRPEIVTLYYQTLGKPEPANIWSDDRMTRDDLLGFL--DHVQRTRFEPHIFE 462 Query: 273 D------PQRDIYEP---YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSS 323 P+ D ++ Y+T+ F + L S N + K ++ RPL+ Y+IS+S Sbjct: 463 KIWAKFAPKDDTFDSSLDYWTVDSFNDFLLSSYNL-----FVKPETNLNRPLNEYYISTS 517 Query: 324 HNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVL 383 HNTYL G Q + SS E Y+R L+SGCR +E+D WDGPD P + HG T T+ + DV Sbjct: 518 HNTYLIGRQVADTSSEEGYIRALQSGCRSVEIDIWDGPDDRPVVKHGRTFTSSVSVEDVC 577 Query: 384 RTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 I+++ FI S PLILS+E +CS Q ++ + FG+ L+ P+ +LPSPH+ Sbjct: 578 SAIRKYGFIASPNPLILSLEIHCSASNQLKVVDILKGTFGENLVTQPLVPGALNLPSPHE 637 Score = 108 bits (260), Expect = 8e-22 Identities = 84/274 (30%), Positives = 130/274 (47%), Gaps = 22/274 (8%) Query: 931 TWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTF-FVKYH 989 T +I + +L +Y + + F + N SF E K + EN +K++ Sbjct: 700 TKKIVPALGELGVYVQGLKFRNFAFP-ESKTTNHCFSFSERKFISICKDPENREQMMKHN 758 Query: 990 TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049 L+RIYP G R+ SSN NP+ FW G+QMVALN+QT D P Q+N F G G++L Sbjct: 759 RRYLTRIYPSGYRVKSSNLNPLYFWQNGAQMVALNWQTYDLPAQLNDAMFAARG--GYVL 816 Query: 1050 KPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCK---TGRGTASPFVEVEIIGAD 1106 KP ++ + ++ +V L I A+ L + G+ + P++ ++ G Sbjct: 817 KPPYL----------RHLKSPRSGHSVNLSFISAQQLPRPKDLGKSSFDPYIVAQLHGPG 866 Query: 1107 YDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPL 1166 + KL T V DNG NP WN + +PE FV ++ + + L Sbjct: 867 ENH--KLKTSPVIDNGFNPRWNKDWSLSL-SPEDYEFSFV--QITLYTQDRPFAVSCLRL 921 Query: 1167 LCLRKGYRSVPLTNAFSEELELSTLMVHLSIITD 1200 L +GYR VPL + EE STL + +S I++ Sbjct: 922 SSLNEGYRHVPLNDLQGEEYLFSTLFMKVSKISN 955 >UniRef50_Q5KJZ5 Cluster: Phosphoinositide phospholipase C, putative; n=2; Filobasidiella neoformans|Rep: Phosphoinositide phospholipase C, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 604 Score = 153 bits (372), Expect = 2e-35 Identities = 67/135 (49%), Positives = 95/135 (70%), Gaps = 1/135 (0%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 QDMT PL HY+ISSSHNTYL G+Q+ ES++E Y+R L +GCRC+E+D G D P +Y Sbjct: 158 QDMTHPLQHYFISSSHNTYLVGEQWKGESTVEGYIRVLLAGCRCVEMDVQSG-DVEPVVY 216 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 H TLT+ + D+ R IK++ F+TS YP+I+S E +C+ QQ R+A ++VFGD+L+ Sbjct: 217 HRKTLTSSVPVRDICRAIKQYGFVTSPYPIIISTEIHCASEQQNRLAIILKEVFGDMLVS 276 Query: 429 HPMDKNETSLPSPHD 443 P+ + + LPSP D Sbjct: 277 APLVEEFSELPSPED 291 Score = 93.5 bits (222), Expect = 3e-17 Identities = 72/273 (26%), Positives = 134/273 (49%), Gaps = 28/273 (10%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 K ER + ++S+L++Y V + ++ ++ + S E A +++ + + ++ Sbjct: 343 KTERPDIFSPQLSELLVYTHGVKYQ-GFSKLNEYLPSHQFSVSERTAAKILKENK-VDWI 400 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 K++ +SR+YP+G R+ S+N+NPV W+ G Q+VALN+QT D+ + +N F + G Sbjct: 401 KHNFKHISRVYPRGTRLGSTNFNPVDSWSAGCQIVALNWQTLDESILLNHAMFHDSN--G 458 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR-HLCKTGRGTASPFVEVEIIGA 1105 +ILKP + E K +E K + + + G R LC A +VE + G Sbjct: 459 YILKPLSLRE--------KVVEVPEKYLLTVRIISGQRTPLC------ADLYVEAILNGK 504 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEV-ANPELALIRFVVQDEDIFGEPNFIGQATF 1164 + T+ +S LNPLW++ FE+ + P L ++ F+ + Q Sbjct: 505 -----ISKRTRALSQVTLNPLWDETLTFEITSTPSLLMLNFLHLE---VRNKALQAQWMR 556 Query: 1165 PLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 P+ +GY +PL ++ +TL V +++ Sbjct: 557 PVSLAPRGYHHLPLYDSLLSRFVFATLFVKITV 589 >UniRef50_Q4PA81 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 1491 Score = 153 bits (371), Expect = 3e-35 Identities = 71/140 (50%), Positives = 92/140 (65%), Gaps = 5/140 (3%) Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366 + DMTRPLS Y+ISSSHNTYL G Q+ +S++E Y+R L G R +ELDCWDGP+ P Sbjct: 720 IQHDMTRPLSEYYISSSHNTYLVGGQWKGDSTVEGYIRALLQGARSVELDCWDGPNNVPQ 779 Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426 I HG TLT+++ F DV+ I +AF+TS YPLILS+E + PQQ MA D G++L Sbjct: 780 ITHGRTLTSRVPFQDVISAIARYAFVTSPYPLILSLEVHADPPQQEVMARILIDTLGEML 839 Query: 427 LVHPMDK-----NETSLPSP 441 L P+D + LPSP Sbjct: 840 LSQPIDSQTLPGSTDELPSP 859 Score = 78.2 bits (184), Expect = 1e-12 Identities = 45/143 (31%), Positives = 77/143 (53%), Gaps = 9/143 (6%) Query: 958 KGFVYNEMSSFPETKAERLMSQQ-ENTFFVKYHTTQLSRIYPKGQ---RIDSS-NYNPVP 1012 + + M S E A +++ N +K++ + L+RIYP R+ +S N+ P+ Sbjct: 1012 ESYATQHMVSLSEKTALKMIRDPISNEALIKHNRSHLTRIYPSMMSFARLHASRNFVPLD 1071 Query: 1013 FWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVK 1072 W G Q+VALN+QT D ++N F +NG CG++LKP + + + K+++GKV Sbjct: 1072 MWAAGCQLVALNWQTTDLGFELNQAMFSRNGRCGYVLKPAALRTKEHG----KTLQGKVV 1127 Query: 1073 PVTVMLRVIGARHLCKTGRGTAS 1095 + LR++ A+ L K + AS Sbjct: 1128 RFQLDLRIVSAQQLPKKNKAGAS 1150 Score = 52.4 bits (120), Expect = 7e-05 Identities = 49/210 (23%), Positives = 91/210 (43%), Gaps = 13/210 (6%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129 +++ ++EVR G S+ + R S+ TI Y + +A +D+ W Sbjct: 324 VNLESIREVRFGPSAASY-RTSLNISSAHESRWLTIIYQNNGIYKALHLIALSDQSLSRW 382 Query: 130 VKGVLYL------IAEAVSASYPLQIER--WLRKEFYSIENSH-EKITLKEVKAFLPKIN 180 +L+L + AV AS L+ R W+R + + S+ EK++++EV ++ Sbjct: 383 RASLLHLQSLRRELLGAVGASSSLENRRHLWMRHHWKDADESNDEKLSIEEVILLCRRLG 442 Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240 + + + LR F D RG + F DF + L+ +++ IF ++ Sbjct: 443 IESNKAHLRRCFNLADWRNRGFLDFQDFQ-HFVSLLKQRADIETIFAAWADQPLEQPLEQ 501 Query: 241 LREFQNFLRDEQHDNLGD-DEVQASQFIRD 269 LR +D+ HD G E++ S + D Sbjct: 502 LRRGSGVTKDD-HDLRGQAPELEGSPALSD 530 >UniRef50_O97033 Cluster: PLC-betaS; n=1; Ephydatia fluviatilis|Rep: PLC-betaS - Ephydatia fluviatilis Length = 1355 Score = 151 bits (366), Expect = 1e-34 Identities = 130/398 (32%), Positives = 190/398 (47%), Gaps = 31/398 (7%) Query: 71 DIRDVKEVRTGK----SSK--DFERWPEETKRLESSKCFTIYYGTE--FKLRCASFVAQT 122 D+ + +VR GK SK +F R + LE + T+ Y E L +A + Sbjct: 64 DVTHISDVRAGKVPYKDSKLHEFLRSMTSSDYLEPEQFLTMVYRREGIVNLDHVQLMAPS 123 Query: 123 DKECEAWVKGVLYLIAEAV--SASYPLQIERWLRKEFYSIENSHEKITLKEV-KAFLPKI 179 E W + V ++ + +AS +R ++ S N + +I +K + +A L ++ Sbjct: 124 MDVAEKWKRAVNAIVFNMLRFNASTLTFFKRNYQRILLSC-NGYGQIPVKSICRALLLRV 182 Query: 180 NCKISTSKLRDVFQ------DVDTEKRGEIGF--DDFAVLYQKLIFDENNVQDIFDKYSV 231 K + +L +F D TE + F D + L +L + + K Sbjct: 183 RDK-TDMELFGIFDAQKKKMDDGTEYIQDTDFTWDKYEQLVNQLTKGRTSDMECVIKDLG 241 Query: 232 YCSNGTTITLREFQNFLRDEQHD---NLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEF 288 +TL+EF NFL Q D N Q ++ + E T Sbjct: 242 KSKKHQQLTLQEFHNFLTKCQRDPRLNTILYPPPTKQQAKELAEKYEGKAVEDRLTPRAL 301 Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348 + L S+ N++ + DMT+PLSHY+I+SSHNTYLTG Q S S++E Y +CL Sbjct: 302 LNFLMSEDNNVLGVENLDQFMDMTQPLSHYFINSSHNTYLTGHQLRSLSTVEMYRQCLLL 361 Query: 349 GCRCIELDCWDGPDGTPFIY-HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407 GCRC+ELD W P+G I HG TL TKI F DV+ I E+AFITSE+P+ILSIE++C Sbjct: 362 GCRCVELDLW--PEGEDIIITHGGTLCTKIPFKDVVEAISEYAFITSEFPVILSIENHCR 419 Query: 408 LPQQ--RRMASAFQDVFGDLLLVHPMDKN--ETSLPSP 441 +++AS F VFGD L P+D E LP P Sbjct: 420 HKPLLIQKIASTFALVFGDKLQKSPLDDYPLEPGLPLP 457 Score = 149 bits (360), Expect = 6e-34 Identities = 94/265 (35%), Positives = 143/265 (53%), Gaps = 17/265 (6%) Query: 940 DLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPK 999 D+I YC +TF K SSF E K L+ F VKY+ Q+SRIYP+ Sbjct: 767 DIINYCSGITFEGFEAAEKTNCSFYQSSFNEDKGVSLVKVTAREF-VKYNMRQMSRIYPQ 825 Query: 1000 GQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG- 1058 G RI+SSNY P FWN G Q+VALN+Q+ D P+Q+N K++ NG G++LKP +E Sbjct: 826 GGRINSSNYMPQIFWNVGCQLVALNFQSTDLPIQLNNAKYEFNGVTGYLLKPAAYLKERT 885 Query: 1059 ----YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLV 1114 +NP + +E + P T+ L+VI L T + T + VE ++ G D+ V Sbjct: 886 TGGLFNPFIQNPVE-NIVPATLTLKVISGIFL--TEKRT-NCLVEAQMFGLPSDT-VNHK 940 Query: 1115 TKTVSDNGLNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKG 1172 T +P+W+ ++ PE+A++R V DED +GQ + P+ +R G Sbjct: 941 FYTTKKEAPHPVWDHEPFTFAKILLPEMAMLRVAVYDED----RELLGQRSLPVNAIRAG 996 Query: 1173 YRSVPLTNAFSEELELSTLMVHLSI 1197 YR +PL + +++ L L++L VH+ + Sbjct: 997 YRHIPLRDKYNQPLSLASLFVHIMV 1021 >UniRef50_Q75C92 Cluster: ACR024Wp; n=1; Eremothecium gossypii|Rep: ACR024Wp - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 877 Score = 151 bits (366), Expect = 1e-34 Identities = 103/369 (27%), Positives = 184/369 (49%), Gaps = 32/369 (8%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129 L++ +K++R + +K++ + S IY + KL+ +A T EC + Sbjct: 166 LELDTIKDIRMAEMAKNYREQYDIMDAFASRWITIIYQVSPTKLKALHLIAPTQLECAKF 225 Query: 130 VKGVLYL------IAEAVS--ASYPLQIERW-LRKEFYSIENSHEKITLKEVKAFLPKIN 180 VL + + E++S +S W + + S + ++ ++V+ K + Sbjct: 226 YNAVLTVARQRRELMESISVPSSEAFANIHWKVNVSSKKADESRDTLSFEDVQRLCTKFH 285 Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240 S++ L+ VF+ D + G + F +F + +++ + V +I+ K + + I Sbjct: 286 IYCSSNYLKRVFKIADVNRNGLLNFSEFCT-FVRMLKKRHEVTEIWQKIA---AETRAID 341 Query: 241 LREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEML-YSKQNSI 299 +F +FL D Q +++ +Q RD + + Y L +F+ Y+++ Sbjct: 342 FEKFYSFLTDVQCEDMD------AQLARDLFNEYSHEGYMDEDLLLKFLTAQPYARE--- 392 Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359 + +D +RPLS Y+ISSSHNTYL G+Q S +S+E Y++ L+ GCR +E+D WD Sbjct: 393 -------IEEDYSRPLSEYFISSSHNTYLLGNQVGSMASVEGYIQALQQGCRSVEIDIWD 445 Query: 360 GPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQ 419 DG P + HG LT+ + +V+ I ++AFITS YPLILS+E +C Q + F Sbjct: 446 SDDG-PVVCHG-KLTSSLPLRNVVDVINKYAFITSPYPLILSLEIHCRSEGQIIVKQLFD 503 Query: 420 DVFGDLLLV 428 D+ G L+ V Sbjct: 504 DILGPLIYV 512 Score = 79.0 bits (186), Expect = 7e-13 Identities = 63/232 (27%), Positives = 102/232 (43%), Gaps = 30/232 (12%) Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNG--- 1043 K++ L R+YP R SSNY+P+ W G QMVA N+QT D Q+N F+ Sbjct: 640 KHNRRHLMRVYPHAFRYKSSNYDPIKCWRLGVQMVATNWQTYDLGQQLNQAMFRVTARDD 699 Query: 1044 ---GCGFILKPQFMFEEGYNPCDKKSIEGKV--KPVTVMLRVIGARHLCK------TGRG 1092 G++ KP+++ + I V V + L ++ A+ L K G Sbjct: 700 WPWPSGYVRKPEYLLHTVPKTSFIRDIYEAVHSSVVALSLELLSAQLLPKPKLSSRDGEA 759 Query: 1093 TASPFVEVEIIG------ADYDSGVKLVTKTVS-----DNGLNPLWNDICEFEVANPELA 1141 +P+V +E++G +G+ V+ +NG NP+W + N Sbjct: 760 HFAPYVVIEVLGDGLCGPIHVQNGLVTAPNQVTSCRCPENGFNPVWKTSLTATLNNTGFN 819 Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 IR++V++ DI + L +++GYR +PL + S STL V Sbjct: 820 FIRYIVKNADI-----TLATCCIRLDYMKRGYRHIPLYSLESSRFIFSTLFV 866 >UniRef50_Q00722 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; n=18; Euteleostomi|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 - Homo sapiens (Human) Length = 1181 Score = 151 bits (366), Expect = 1e-34 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%) Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348 V L +NS+ + DMT+PL+HY+I+SSHNTYLT QFS SS E Y + L S Sbjct: 292 VWFLCGPENSVLAQDKLLLHHDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 351 Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406 GCRC+ELDCW G PD P I HG T+TT I F + + I E AF TS YP+ILS E++ Sbjct: 352 GCRCVELDCWKGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFENHV 411 Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443 P QQ +MA + +FGD+LL P++ K LPSP D Sbjct: 412 DSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGVPLPSPED 453 Score = 144 bits (350), Expect = 1e-32 Identities = 100/270 (37%), Positives = 146/270 (54%), Gaps = 20/270 (7%) Query: 936 KEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +E+S L+ Y + V+F + + +V +SSF E KA L+S+ + FV Y+ Q Sbjct: 540 EEMSSLVNYIQPTKFVSFEFSAQKNRSYV---ISSFTELKAYDLLSKA-SVQFVDYNKRQ 595 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 +SRIYPKG R+DSSNY P FWN G QMVALN+QT D PMQ NM F+ NG G++LK + Sbjct: 596 MSRIYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMAVFEFNGQSGYLLKHE 655 Query: 1053 FMF--EEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSG 1110 FM ++ +NP I+ V T+ + VI + L + T +VEVE+ G D Sbjct: 656 FMRRPDKQFNPFSVDRID-VVVATTLSITVISGQFLSERSVRT---YVEVELFGLPGDPK 711 Query: 1111 VKLVTK-TVSDNGLNPLW-NDICEFE-VANPELALIRFVVQDEDIFGEPNFIGQATFPLL 1167 + TK + S N +NP+W + FE + PELA +R V +E F+G P+ Sbjct: 712 RRYRTKLSPSTNSINPVWKEEPFVFEKILMPELASLRVAVMEEG----NKFLGHRIIPIN 767 Query: 1168 CLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L GY + L + + L + L + L + Sbjct: 768 ALNSGYHHLCLHSESNMPLTMPALFIFLEM 797 >UniRef50_Q6FY00 Cluster: Similar to sp|P32383 Saccharomyces cerevisiae YPL268w PLC1 1- phosphatidylinositol-4; n=1; Candida glabrata|Rep: Similar to sp|P32383 Saccharomyces cerevisiae YPL268w PLC1 1- phosphatidylinositol-4 - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 850 Score = 150 bits (363), Expect = 3e-34 Identities = 108/381 (28%), Positives = 177/381 (46%), Gaps = 32/381 (8%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKECEAW 129 L++ +K +R G+ ++ R S TI Y KL+ +A+ + + + Sbjct: 149 LNLDSIKSIRPGELGSNY-REEYNVDASYSKYWVTIIYKVSNKLKALHVIARDESDYNVF 207 Query: 130 VKGVLYLIAEAVSASYPLQIE--------RWLRKEFYSI-ENSHEKITLKEVKAFLPKIN 180 V L+ L + W R + E + E + ++V+ + + Sbjct: 208 CSLVFGLVRTRRELMESLAVPDHDKFADIHWNRALSRNPDEKAEEVLGFEDVRQMCQRFH 267 Query: 181 CKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTIT 240 S LR F DT G + F++F V + KL+ + D++ + + +T Sbjct: 268 IYCSAGYLRRFFDAADTNNSGTLSFEEFQV-FVKLLKARKEIDDVWQE--AVGLHEDKLT 324 Query: 241 LREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIY 300 F FL + Q + + +DE R +YE Y T + ++ Sbjct: 325 FDTFYKFLTEIQRERMDEDEA--------------RHLYERYETAGGGINKQGFEKYLTT 370 Query: 301 DSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360 +D +RP++ Y+I+SSHNTYLTG Q S+E Y++ L+ GCR +E+D WDG Sbjct: 371 SPYMLPNNEDYSRPMNQYYIASSHNTYLTGKQIGGAPSVEGYIQALQQGCRSVEIDMWDG 430 Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420 + +P + HG LT+ + V + I+++AFITS YPLI+S+E C+ QR AS F+D Sbjct: 431 -ESSPVVCHG-VLTSALPLSSVTQIIRKYAFITSPYPLIISMEVRCNSKNQRIAASIFKD 488 Query: 421 VFGDLLLVHPMDKNETSLPSP 441 FGDLL D++E LPSP Sbjct: 489 TFGDLLYTCE-DRSE--LPSP 506 Score = 65.7 bits (153), Expect = 7e-09 Identities = 68/255 (26%), Positives = 108/255 (42%), Gaps = 33/255 (12%) Query: 967 SFPETKAERLMSQQENTFFV-KYHTTQLSRIYPKGQRIDSSNY-NPVPFWNCGSQMVALN 1024 S E + ++++ + V K++ + R+YP R S+N+ +PV FW G QMVA N Sbjct: 603 SLDERRLDKMLGDAQVAAAVDKHNRRHMMRVYPHALRYRSTNFEDPVRFWRLGVQMVATN 662 Query: 1025 YQTPDKPMQVNMGKF------KQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVML 1078 +QT D Q+N+ F +Q G++LKP ++ P K+ E + V Sbjct: 663 WQTNDVGHQLNVAMFQLNTRNQQQMPSGYVLKPGWL----ARPPSKRRRERCGAVLRVTF 718 Query: 1079 RVIGARHLCKTGRGTASPFVEVEIIGAD-YDSGVKLVT-------KTVS------DNGLN 1124 VI A+ L T + I A+ D VT TV +NG + Sbjct: 719 EVISAQLLPNLSESTETKSQAASIGAAETEDPYYTQVTCEMFSCGSTVEKSSKCHENGFS 778 Query: 1125 PLWNDICEFEVANPE--LALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAF 1182 P+W +V E +R VV+ + + + LR+GYR +PL + Sbjct: 779 PVWRSALSQDVRRDEYPFVFVRVVVRRCE-----EVVATTCVRVCQLREGYRHIPLCSPD 833 Query: 1183 SEELELSTLMVHLSI 1197 E+ STL V + Sbjct: 834 GEQYVFSTLFVRYRV 848 >UniRef50_A3KGF7 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; n=15; Eutheria|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 - Mus musculus (Mouse) Length = 1181 Score = 149 bits (362), Expect = 3e-34 Identities = 79/162 (48%), Positives = 100/162 (61%), Gaps = 7/162 (4%) Query: 289 VEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRS 348 V L +NS+ + QDMT+PL+HY+I+SSHNTYLT QFS SS E Y + L S Sbjct: 292 VWFLCGPENSVLAHDTLLIHQDMTQPLNHYFINSSHNTYLTAGQFSGLSSAEMYRQVLLS 351 Query: 349 GCRCIELDCWDG--PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNC 406 GCRC+ELDCW G PD P I HG T+TT I F + + I E AF TS YP+ILS E++ Sbjct: 352 GCRCVELDCWKGKPPDEEPIITHGFTMTTDILFKEAIEAIAESAFKTSPYPVILSFENHV 411 Query: 407 SLP-QQRRMASAFQDVFGDLLLVHPMD----KNETSLPSPHD 443 P QQ +MA + +FG+ LL P++ K LPSP D Sbjct: 412 DSPRQQAKMAEYCRSMFGETLLTDPLENFPLKPGIPLPSPED 453 Score = 145 bits (351), Expect = 7e-33 Identities = 99/269 (36%), Positives = 144/269 (53%), Gaps = 18/269 (6%) Query: 936 KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994 +E+S L+ Y + F + E K Y +SSF E KA L+S+ F V Y+ Q+S Sbjct: 545 EEMSSLVNYIQPTKFISFEFSAQKNRSY-VVSSFTELKAYELLSKASMQF-VDYNKRQMS 602 Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054 R+YPKG R+DSSNY P FWN G QMVALN+QT D PMQ NM F+ NG G++LK +FM Sbjct: 603 RVYPKGTRMDSSNYMPQMFWNAGCQMVALNFQTMDLPMQQNMALFEFNGQSGYLLKHEFM 662 Query: 1055 --FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112 ++ +NP I+ V T+ + +I + L + T +VEVE+ G D + Sbjct: 663 RRLDKQFNPFSVDRID-VVVATTLSITIISGQFLSERSVRT---YVEVELFGLPGDPKRR 718 Query: 1113 LVTK-TVSDNGLNPLWND---ICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLC 1168 TK + + N +NP+W + I E ++ PELA +R V +E F+G P+ Sbjct: 719 YRTKLSPTANSINPVWKEEPFIFE-KILMPELASLRIAVMEEG----SKFLGHRIIPINA 773 Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L GY + L + + L + L V L + Sbjct: 774 LHSGYHHLCLRSESNMALTMPALFVFLEM 802 >UniRef50_UPI00015A791C Cluster: UPI00015A791C related cluster; n=1; Danio rerio|Rep: UPI00015A791C UniRef100 entry - Danio rerio Length = 658 Score = 149 bits (361), Expect = 5e-34 Identities = 87/217 (40%), Positives = 128/217 (58%), Gaps = 13/217 (5%) Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047 Y+ Q+SRIYPKG R+DSSNY P FWN G QMV+LN+QTPD MQ+N GKF+ NG CG+ Sbjct: 271 YNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLGMQLNQGKFEYNGACGY 330 Query: 1048 ILKPQFM--FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGA 1105 +LKP FM + ++P + ++G V T ++V + L GT +VEV++ G Sbjct: 331 LLKPDFMRRGDRMFDPFSETPVDG-VIAATCSVQVFSGQFLSDKKIGT---YVEVDMYGL 386 Query: 1106 DYDSGVK-LVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDEDIFGEPNFIGQA 1162 D+ K T+ V +NGLNP +N+ ++ P+LA++R V D++ IGQ Sbjct: 387 PTDTIRKEFRTRMVMNNGLNPYYNEEPFVFRKLILPDLAVLRIAVFDDN----SKLIGQR 442 Query: 1163 TFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSIIT 1199 PL L+ GYR + L N ++ L L T+ ++ + T Sbjct: 443 LLPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKT 479 Score = 93.1 bits (221), Expect = 4e-17 Identities = 48/99 (48%), Positives = 62/99 (62%), Gaps = 4/99 (4%) Query: 288 FVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCL 346 F L S +N+ ++ + D + Q+M PLSHY+ISSSHNTYLTG QF +SS+E Y + L Sbjct: 8 FCRYLMSDENAPVFLDRLD-LCQEMEHPLSHYFISSSHNTYLTGRQFGGKSSVEMYRQVL 66 Query: 347 RSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRFMDVL 383 SGC ELDCWD G D P I HG + T I F ++ Sbjct: 67 LSGCYTKELDCWDGKGEDQEPIITHGKAMCTDILFKQII 105 >UniRef50_P32383 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1; n=2; Saccharomyces cerevisiae|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 - Saccharomyces cerevisiae (Baker's yeast) Length = 869 Score = 148 bits (359), Expect = 8e-34 Identities = 116/386 (30%), Positives = 195/386 (50%), Gaps = 33/386 (8%) Query: 70 LDIRDVKEVRTGKSSKDFERWPEETKRLES-SKCF-TIYYGTEFKLRCASFVAQTDKECE 127 L++ VK++R G ++ ++ + KRL S SK + I Y KL+ VA + + Sbjct: 146 LELDSVKDIRIGDTASTYQE-EVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFN 204 Query: 128 AWVKGVLYLIA------EAVSASYPLQIERWLRKEFYSIENSHEK---ITLKEVKAFLPK 178 ++ + L+ E++ Q R + S + EK ++ +VK K Sbjct: 205 TFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDK 264 Query: 179 INCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTT 238 + +ST +L + FQ D G + + +F + K++ + V I+ K++ + Sbjct: 265 FHIYVSTGQLLEFFQLADINHNGLLNYFEFEK-FIKILKNRKEVNMIWSKFTK--PPHSH 321 Query: 239 ITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSEFV-EMLYSKQN 297 ++ F FL EQH+ + D + S FI+ Y Q + + FT +F+ E Y + Sbjct: 322 LSFENFFQFLITEQHEQV-DRQTAWSYFIK-YREPTQLTMGQDGFT--KFLKEQPYLVE- 376 Query: 298 SIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDC 357 + + Y K PL+HY+I+SSHNTYL G Q + S+E Y++ L+ GCRC+E+D Sbjct: 377 -VKEELYSK-------PLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDI 428 Query: 358 WDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASA 417 WDG +G P + HG LT+ I V+R IK++AFITS YPLI+S+E NC+ Q+ + Sbjct: 429 WDGENG-PVVCHGF-LTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLI 486 Query: 418 FQDVFGDLLLVHPMDKNETSLPSPHD 443 ++V + L + + LPSP + Sbjct: 487 MREVLAEQL--YFVGTRTDKLPSPRE 510 Score = 102 bits (244), Expect = 7e-20 Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 34/261 (13%) Query: 967 SFPETKAERLMSQQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025 S E K E ++ + + H + L R+YP R SSN+NP+PFW G QMVA N+ Sbjct: 614 SLNERKVEYMIKDKHLKLSLDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNW 673 Query: 1026 QTPDKPMQVNMGKFK----QNGG---CGFILKPQFMF----EEGYNPCDKKSIEGKVKPV 1074 QT D Q+N+ F+ Q G G++LKP+ + + P + E PV Sbjct: 674 QTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPV 733 Query: 1075 TVMLRVIGARHL-----CKTGRGTASPFVEVEIIGAD-------YDSGVKL-----VTKT 1117 TV +R++ + L R + FV+VE D D G ++ TK+ Sbjct: 734 TVKIRILSTQLLPRLNDTSPSRNNTNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKS 793 Query: 1118 VSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVP 1177 NG NP+W+ + + +L I+F+V E I L LR GYR +P Sbjct: 794 SQGNGFNPIWDAEVSITLKDTDLTFIKFMV-----ISEETQIASVCLKLNYLRMGYRHIP 848 Query: 1178 LTNAFSEELELSTLMVHLSII 1198 L N E+ TL +H I+ Sbjct: 849 LFNMEGEQYIFCTLFIHTQIL 869 >UniRef50_A7TR21 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 873 Score = 147 bits (357), Expect = 1e-33 Identities = 111/384 (28%), Positives = 186/384 (48%), Gaps = 33/384 (8%) Query: 67 EGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKEC 126 E +L+I +K++R + ++ + S+ T+ + KL+ +A + Sbjct: 146 EKSLEIDSIKDIRVDTLAINYRK-EYNIPDSSSNLWITVIFEVSKKLKALHLIANKHTDF 204 Query: 127 EAW---VKGVL-YLIAEAVSASYPLQIERWLRKEFYSI------ENSHEKITLKEVKAFL 176 + + + G++ Y S S P + E++ ++S + S + ++ ++K Sbjct: 205 QTFCTCIGGLVKYRYDLMKSVSVP-ESEKFANIHWHSSVSEKKEDESKDTLSFVDIKRLC 263 Query: 177 PKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNG 236 K + S+ L F D G + F +F Q L +I + + Sbjct: 264 DKFHIYCSSKHLLKFFTAADINHNGLLNFKEFQTFVQLL----KRRDEIIKVWESLTNCR 319 Query: 237 TTITLREFQNFLRDEQHDNLGDDEVQASQF-IRDYLRDPQRDIYEPYFTLSEFVEMLYSK 295 + L EF F+ Q + E +AS F I + + P + Y L+ F+ L S Sbjct: 320 QYLNLDEFHEFVTKIQKEK----EDKASIFTIYNKFKSPDKK----YMDLNGFINYL-SS 370 Query: 296 QNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIEL 355 Q I D D V D ++PL+HY+I+SSHNTYL G QF S+E Y++ L+ GCRC+E+ Sbjct: 371 QPYIND---DVV--DYSKPLNHYYIASSHNTYLLGKQFGETPSVEGYIQVLQQGCRCVEI 425 Query: 356 DCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMA 415 D WD +G P + H LT+ I +DV I+++AFITS YPLI+S+E NC+ Q + Sbjct: 426 DIWDDENG-PVVCHSF-LTSSIPLLDVASVIRKYAFITSPYPLIISLETNCNKINQLKAV 483 Query: 416 SAFQDVFGDLLLVHPMDKNETSLP 439 S F+D+FGD L + +D + + P Sbjct: 484 SIFKDIFGDSLCTNILDGDALASP 507 Score = 95.9 bits (228), Expect = 6e-18 Identities = 79/254 (31%), Positives = 112/254 (44%), Gaps = 31/254 (12%) Query: 967 SFPETKAERLMSQQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025 S E K E L V H + L RIYP R SSN++P+ W G+QMVA N+ Sbjct: 622 SLNEKKLEHLCKDTTQKLAVDKHNRRFLMRIYPHALRYKSSNFDPIKCWEIGTQMVATNW 681 Query: 1026 QTPDKPMQVNMGKFKQNG------GCGFILKPQFMFEEGYNPCDKKSI--EGKVKPVTVM 1077 QT D Q+N+ FK G+ LKP + E D + E K PVTV Sbjct: 682 QTNDLGHQLNLALFKLTDQKQELLHTGYALKPPKLLPEVTKSRDLTQLYKETKKDPVTVC 741 Query: 1078 LRVIGARHL-----CKTGRGTASPFVEVEII-------GADYDSGVKLVTKTVS-----D 1120 + ++ + L K+ T +P+V E I G L K S + Sbjct: 742 ITLLSGQLLPKPKNIKSNEDTFAPYVVTEFICNCEPVKPLMVKFGTALSPKVCSTPRCKE 801 Query: 1121 NGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180 NG +P WN + + ELA ++F V+ E+ + + T L +RKGYR +PL N Sbjct: 802 NGFSPTWNTEMCITLKDIELAFVKFTVKTEE-----SILASCTLKLDYIRKGYRHIPLYN 856 Query: 1181 AFSEELELSTLMVH 1194 E+ STL ++ Sbjct: 857 PKGEKYIFSTLFIN 870 >UniRef50_O13433 Cluster: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1; n=3; Candida|Rep: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1 - Candida albicans (Yeast) Length = 1099 Score = 140 bits (339), Expect = 2e-31 Identities = 95/320 (29%), Positives = 162/320 (50%), Gaps = 51/320 (15%) Query: 159 SIENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDV------DTEK-------RGEIGF 205 S ++ E ++ ++ + ++N ++T+ L+ +F V TEK + F Sbjct: 409 SHKHVREFLSFNDILKYSKRLNINVNTNHLQQIFDQVLLLSSATTEKPVSTPLFEKGLNF 468 Query: 206 DDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQ 265 + F + ++ D ++Q+I+D + + E +NF+ + Q +N DD+ ++ Sbjct: 469 EQFKQ-FVSILKDRKDLQEIWDSLA---QGKEVLQFDEIKNFIINIQKENFSDDDDNSTI 524 Query: 266 FIRDYLRDPQRDIYEPYFTLSEF--VEMLYSKQNSIYDSQYDKVTQDMTR----PLSHYW 319 + I++ Y + E L S Y + Y ++TQ T PL+ Y+ Sbjct: 525 NL----------IFQKYCSNDNGWNKESLNEYLLSSYSTPYREITQTQTNYYDYPLNEYF 574 Query: 320 ISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT--------------- 364 ISSSHNTYLTG Q + +SS+E Y+R L+ GCRC+E+D W+G T Sbjct: 575 ISSSHNTYLTGRQVAGDSSVEGYIRTLQRGCRCVEIDIWNGDSNTTTTTVIGTKDDDDKN 634 Query: 365 ---PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDV 421 P + HG T T I F +V+R IK+ AFI S +PLILS+E +CS Q ++ + +D+ Sbjct: 635 EYEPIVNHGRTFTKPISFANVIRAIKKFAFIVSPWPLILSLEIHCSPECQIKVVNILKDI 694 Query: 422 FGDLLLVHPMDKNETSLPSP 441 G+ +++ P+D + LPSP Sbjct: 695 LGENMIIAPIDIDSVILPSP 714 Score = 90.2 bits (214), Expect = 3e-16 Identities = 79/303 (26%), Positives = 131/303 (43%), Gaps = 36/303 (11%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I E+S+L IY + + F L + +N S E R++ + + H + Sbjct: 790 KIINELSNLGIYTQGIKFRNFSLP-ESKTFNHCFSLGEKSINRMIKDDDKKISLDKHNRR 848 Query: 993 -LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 L R+YP G R+ SSN+NP+P+W+ G QMVA N+QT D Q+N F+ G++LKP Sbjct: 849 YLMRVYPSGTRLKSSNFNPLPYWSHGVQMVATNWQTYDLGQQLNEALFENKIFQGYVLKP 908 Query: 1052 QFM----FEEGYNPCDKKS--IEGKVKPVTVMLRVIGARHLCKTGRG-----TASPFVEV 1100 + + + D ++ K + +I L K + +P++ Sbjct: 909 SVLRKPTLKSSSSNVDTRTSLTTTNSKTIRFNFEIISGHQLPKFPKDDYKDQAINPYISF 968 Query: 1101 EIIGA---DYD-------------SGVKLVTKTVSDNGLNPLWNDICEFEV--ANPELAL 1142 EIIGA +D S TK + +NG NP +N + +L Sbjct: 969 EIIGAQDVQWDNNDSSPIAPTTSSSPFIRTTKIIRENGFNPNFNTKFSGSIITTTNDLIF 1028 Query: 1143 IRFVVQDEDIFGEPNF-----IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 I+FVV P++ I L L++GYR + L + E+L S++ + + Sbjct: 1029 IKFVVYASTSLNYPDYGENFPIAILVTKLNYLKQGYRYIYLNDLLGEQLVYSSIFIKIEY 1088 Query: 1198 ITD 1200 D Sbjct: 1089 DED 1091 >UniRef50_UPI00015551EC Cluster: PREDICTED: hypothetical protein, partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein, partial - Ornithorhynchus anatinus Length = 650 Score = 135 bits (326), Expect = 8e-30 Identities = 122/488 (25%), Positives = 205/488 (42%), Gaps = 31/488 (6%) Query: 5 CFNGA-KDRLIHEADQLISYIERGSTVLKFFPRKRPERRALCVRRETHQVLWSRINAPQR 63 CF+ ++ I A IS+++ G + K P R R + + + W P + Sbjct: 15 CFSSMPSEKKISSAGDCISFMQAGCELKKVRPNSRLYNRFFTLDGDLQALRWE----PSK 70 Query: 64 QGYEGA-LDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQT 122 + + A LDI ++E+R GK+++ F R +L +I +G +++ VA++ Sbjct: 71 KDPDKARLDISAIREIRPGKNTETF-RHNGLADQLCEDCALSILHGDDYE--SLDLVARS 127 Query: 123 DKECEAWVKGVLYLIAEAVSASYPLQIER------WLRKEFYSIENSHEKITLKEVKA-F 175 WV G+ YL++ P R WLR F + I +E Sbjct: 128 ADVANIWVSGLRYLVSRLRQGPDPPGAGREPPRLAWLRSVFEEADEEGNGILPEEAAVRL 187 Query: 176 LPKINCKISTSKLRDVFQDVDTEKRG---EIGFDDFAVLYQKLIFDENNVQDIFDKYSVY 232 + ++ + +++R F+++ K + ++F ++ +L +++ Sbjct: 188 IRRLAPALKEARIRLRFKEIQRSKEKLTTRVTREEFCEVFGELC----TRPEVYFLLVQI 243 Query: 233 CSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYE-PYFTLSEFVEM 291 N + + FL EQ G E +R Y +P + + + F Sbjct: 244 SKNKEFVDAGDLLLFLEAEQ-GVAGASEDLCRDIVRRY--EPSEEGRRLGFLAIDGFTRY 300 Query: 292 LYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSES-SLEAYVRCLRSGC 350 L S + ++D + KVTQDM+RPLSHY+ISSS + ++ + + Y R LR+GC Sbjct: 301 LLSPECDLFDPEQRKVTQDMSRPLSHYYISSSRSPRWAAERRGGPADEVRGYERALRTGC 360 Query: 351 RCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQ 410 R ++LD DGPDG P + R L I AF S +PLIL ++ CS+ Q Sbjct: 361 RSVQLDVRDGPDGEPVLDGAAPAPPSFRL--ALEVIDRFAFAASAFPLILCLDHRCSVQQ 418 Query: 411 QRRMASAFQDVFGDLLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQE- 469 Q+ MA + VFG L + LPSP + P G V + Sbjct: 419 QKVMARHLKGVFGPKLFGGRPPGPDAPLPSPEELRGRVVVEGRKLPPGWTAPEGDVPDDR 478 Query: 470 EGKDLDLR 477 +G DL R Sbjct: 479 DGADLPQR 486 >UniRef50_Q0UC00 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 980 Score = 134 bits (325), Expect = 1e-29 Identities = 60/126 (47%), Positives = 80/126 (63%) Query: 288 FVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLR 347 F L S NS+ + + RPL+ Y+ISSSHNTYL G Q + ESS EAY+ L+ Sbjct: 471 FQTFLTSSNNSVLKPKPSTGKLQLNRPLNEYFISSSHNTYLLGRQVAGESSTEAYISALQ 530 Query: 348 SGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCS 407 GCRCIE+DCWDG DG P + HG TLT I F D ++ + + AF S YPLILS+E N + Sbjct: 531 KGCRCIEIDCWDGGDGLPVVMHGRTLTKAISFHDTIKVVNKFAFAESPYPLILSLEPNAT 590 Query: 408 LPQQRR 413 + ++ + Sbjct: 591 VMEESK 596 Score = 78.2 bits (184), Expect = 1e-12 Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 41/302 (13%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMS--QQENTF 984 K +T I KE+ L +Y R V F + +N + S E K E L +E Sbjct: 599 KKTKTSNITKELGTLGVYTRGVKFT-DFGCTDANTFNHVFSLNERKFETLTKAGSREKYL 657 Query: 985 FVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK-QNG 1043 +++ L R+YP RI S+N++P+ W G QMVALN+QT D Q+N F + Sbjct: 658 LEEHNVRCLMRVYPHAFRITSTNFDPLKCWRRGVQMVALNWQTYDLGQQLNQAMFAGGDD 717 Query: 1044 GCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTA-----SPFV 1098 G++LKP + G + K V ++++ A+ L + RG A +P+V Sbjct: 718 RTGYVLKPTTL-RRGSQTTIHGPRKAPKKEVKFTVQIMSAQQLPRP-RGLAQEANINPYV 775 Query: 1099 EVEIIGADYDSGVKLV-----------------------TKTVSDNGLNPLWNDICEFEV 1135 E E+ A+ D G + T+ V NG NP + + E+ Sbjct: 776 EFEMYCAE-DMGANAIGVGGQDASAPNGHSGIGNPLRKRTEIVPGNGYNPEFQGTKDIEM 834 Query: 1136 ----ANPELALIRFVVQDEDIFGEPNFIGQATF--PLLCLRKGYRSVPLTNAFSEELELS 1189 P L +R+ V N+ A+F L L++GYR +PL ++ E+ S Sbjct: 835 KVTTRFPSLVFVRWTVWHSLDAKTTNYAPLASFTAKLNSLQQGYRHLPLFDSNGEQYLFS 894 Query: 1190 TL 1191 TL Sbjct: 895 TL 896 >UniRef50_A5DAA1 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 921 Score = 134 bits (323), Expect = 2e-29 Identities = 88/301 (29%), Positives = 161/301 (53%), Gaps = 33/301 (10%) Query: 160 IENSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT------EKRGEIGFDDFAVLYQ 213 ++ E + L+++ + ++N + + L+DVF +V T E +G + F+ F + Sbjct: 296 VKEVRELLYLEDILKYSRRLNINLDEAFLKDVFDNVITRVATSSEPKG-LSFEGFKE-FV 353 Query: 214 KLIFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRD 273 +I +++ I++ S+ +TI +F F+ + Q + ++ ++ F+R R+ Sbjct: 354 SIIKRRDDISHIWE---ACFSSLSTIDFDKFCTFMIEIQKEEHNEEHLR-KLFVRFSKRE 409 Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQF 333 + +T F L SK ++I+ + + D PL+ Y+ISSSHNTYL G QF Sbjct: 410 DRL-----IWTKESFNAFLLSKYSTIFKNDFSDDYFD--HPLNDYFISSSHNTYLIGRQF 462 Query: 334 SSESSLEAYVRCLRSGCRCIELDCWDGP--DGT-----------PFIYHGHTLTTKIRFM 380 +SS++ Y+R + GC+C+E+D WDG DG P + HG + T+ I Sbjct: 463 VGDSSIDGYIRAFQRGCKCVEIDIWDGMSIDGDLDNNESEGIKGPIVNHGRSFTSSISLK 522 Query: 381 DVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPS 440 +VL T+K++AF +S +P+ILS+E +C+ Q ++ +D+ G+ L+ +D N+ LPS Sbjct: 523 NVLLTVKKYAFSSSSWPVILSLEVHCNAENQLKIKKLLKDILGESLVTDMLD-NDCVLPS 581 Query: 441 P 441 P Sbjct: 582 P 582 Score = 126 bits (304), Expect = 4e-27 Identities = 91/277 (32%), Positives = 137/277 (49%), Gaps = 20/277 (7%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I E+SDL IY + + F L + +N S E L+S +E + H + Sbjct: 643 KIVTELSDLAIYIQGIKFRNFSLP-ESKTFNHCISLSEKSFNSLLSDEEKRLSLAKHNRK 701 Query: 993 -LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 L R+YP RI SSN+NP+ WN G QMVA N+QT D Q+N F+ GG G+ LKP Sbjct: 702 FLMRVYPSKMRIGSSNFNPITQWNYGVQMVASNWQTYDVGQQINEALFQSCGGTGYALKP 761 Query: 1052 QFMFEEGYNPCDKKSIEGKV-KP-VTVMLRVIGARHLCKT--GRGTASPFVEVEIIGA-- 1105 + + +P KK V +P + L++I A L K+ +PFV VE+ G Sbjct: 762 KSL----RSPLSKKRKPELVQRPLMRFSLKIISALQLPKSKGSNAATNPFVSVEMHGCSL 817 Query: 1106 -DYD-SGVKLVTKTVSDNGLNPLWND--ICEFEVANPELALIRFVVQDE-DIFGEPNF-- 1158 +D + T ++ NG NP+WN+ C N +LA +R VV G+ + Sbjct: 818 IQWDGESQEPSTLIIAANGFNPIWNEQFSCIMSAEN-DLAFLRIVVNSSLSATGKEDIQP 876 Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHL 1195 +G + C++ GYR +P+ + EEL S L+V + Sbjct: 877 LGIIVLRVGCIKDGYRYLPINDPLGEELVYSKLLVRI 913 >UniRef50_Q6CSI9 Cluster: Similar to sp|P32383 Saccharomyces cerevisiae YPL268w PLC1 1- phosphatidylinositol-4; n=1; Kluyveromyces lactis|Rep: Similar to sp|P32383 Saccharomyces cerevisiae YPL268w PLC1 1- phosphatidylinositol-4 - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 976 Score = 129 bits (312), Expect = 4e-28 Identities = 65/133 (48%), Positives = 87/133 (65%), Gaps = 5/133 (3%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIY 368 +D +RPL+ Y+ISSSHNTYL G Q E S+EAY R L+ GCRCIE+D W G G P + Sbjct: 400 EDYSRPLNEYFISSSHNTYLMGKQVVDEVSVEAYTRALQQGCRCIEIDIWQGDHG-PVVC 458 Query: 369 HGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 HG T I DV++TI+++AFITS YPLI+S+E +C Q + +++ GDL+ V Sbjct: 459 HG-LFTQSIPLEDVVKTIRKYAFITSPYPLIVSLEIHCKKDYQLMITKIMKEILGDLIFV 517 Query: 429 HPMDKNETSLPSP 441 P + TSL SP Sbjct: 518 IPPN---TSLLSP 527 Score = 68.5 bits (160), Expect = 1e-09 Identities = 45/125 (36%), Positives = 66/125 (52%), Gaps = 8/125 (6%) Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFK----QN 1042 K++ L RIYP R SSN+NP+ FW G QMVA N+QT D Q+N F+ +N Sbjct: 665 KHNRRHLMRIYPHMLRYKSSNFNPIRFWKEGVQMVATNWQTYDLGQQLNHAMFQVSLDRN 724 Query: 1043 G--GCGFILKPQFMFEEGYNPCDKKSIEGKVK--PVTVMLRVIGARHLCKTGRGTASPFV 1098 G++LKP + +E + D I ++K + + L VI + L +PFV Sbjct: 725 SIWHSGYVLKPAHLRKEIHKMKDIPVIMERLKREKIHIHLDVISGQMLSLQNCKILAPFV 784 Query: 1099 EVEII 1103 E+E+I Sbjct: 785 EIELI 789 Score = 44.8 bits (101), Expect = 0.014 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 5/79 (6%) Query: 1115 TKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYR 1174 TK DNG +P+WN E + N +RF V++ I L L++GYR Sbjct: 894 TKCFRDNGFSPVWNASFECTLTNTTFNFVRFTVKN-----STQTIATTCVRLNYLKQGYR 948 Query: 1175 SVPLTNAFSEELELSTLMV 1193 +PL N E+ STL + Sbjct: 949 HLPLYNIKGEKFIFSTLFI 967 >UniRef50_Q766D4 Cluster: Phosphoinositide-specific phospholipase C; n=1; Physcomitrella patens|Rep: Phosphoinositide-specific phospholipase C - Physcomitrella patens (Moss) Length = 634 Score = 125 bits (301), Expect = 8e-27 Identities = 77/225 (34%), Positives = 117/225 (52%), Gaps = 10/225 (4%) Query: 223 QDIF-DKYSVYCSNGTTITLREFQNFLRDEQHDNLG--DDEVQASQFIRDYLRDPQRD-- 277 QD+ D +S Y NG + FL+ EQ D+ DD + IR+ + Sbjct: 18 QDLLGDVFSTYSENGK-LDAEGLLKFLQTEQGDSKSSLDDAKHLVELIRNERHKSKFPGF 76 Query: 278 IYEPYFTLSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSE 336 I + +F + S N + +S V QDMT+PLSHY+I + HN+YLTG+Q SS+ Sbjct: 77 IVSSDLSKGDFKNYVLSPDLNGVLEST---VHQDMTQPLSHYFIFTGHNSYLTGNQLSSD 133 Query: 337 SSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEY 396 SS L+ G R +ELD W G + HG+TLT+ + F ++ IK +AF++S+Y Sbjct: 134 SSDVPIAAALQRGVRVVELDLWPDDKGGIKVTHGNTLTSPVAFEKCIKAIKANAFVSSKY 193 Query: 397 PLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 P+++++ED+ S P Q A ++ G+ L P LPSP Sbjct: 194 PVVITLEDHLSSPLQALAAETLTNILGEDLYYPPSSDGFKELPSP 238 Score = 120 bits (288), Expect = 3e-25 Identities = 83/250 (33%), Positives = 128/250 (51%), Gaps = 14/250 (5%) Query: 953 ERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVP 1012 +RL+++G V S ETK E++ +++ VK+ + R+YP G R++SSNY+P Sbjct: 381 DRLKVEGTVVR--ISLSETKLEKV-TEEFPELVVKFTQRNILRVYPAGNRVNSSNYDPTA 437 Query: 1013 FWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEE-----GYNPCDKKSI 1067 W G+QMVA N Q K + GKF+ NGGCG+ILKP+++ E+ +NP Sbjct: 438 AWIHGAQMVAQNMQGYGKELWQAHGKFRGNGGCGYILKPKYLLEDLPNGKPFNPSAPGDT 497 Query: 1068 EGKVKPVTVMLRVIGARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLN 1124 + +K V VM + + K SP F + + G D V +V D+ Sbjct: 498 KMILK-VKVMTTMGWDKAFPKYHFDLFSPPDFFTRLLVTGVPAD--VAKWKTSVIDDVWE 554 Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184 P WN+ EF + PELAL+R V+D D + F GQA P+ ++ GYR V + + Sbjct: 555 PHWNEDHEFYLKCPELALLRIEVRDHDEGSQDEFEGQACLPMHEIKDGYRCVQMYDKKGS 614 Query: 1185 ELELSTLMVH 1194 L+ ++ H Sbjct: 615 VLKGVKMLFH 624 >UniRef50_A7PP48 Cluster: Chromosome chr8 scaffold_23, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr8 scaffold_23, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 615 Score = 124 bits (300), Expect = 1e-26 Identities = 82/222 (36%), Positives = 117/222 (52%), Gaps = 13/222 (5%) Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 +++ L R++PK R+DSSNYNP+ W G+QMVA N Q D+P+ + G F+ NGGC Sbjct: 398 IRFTQRNLLRVFPKVMRVDSSNYNPLIGWMHGAQMVAFNMQGYDRPLWLMQGMFRANGGC 457 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV---IG-ARHL--CKTGRGTASP--- 1096 G++ KP + + G P DK PV L+V +G HL T SP Sbjct: 458 GYVKKPDLLLKVG--PHDKVFDPKANLPVKTTLKVKVYMGEGWHLDFHHTHFDIYSPPDF 515 Query: 1097 FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEP 1156 + +V I G DS +K TK V D+ P WN+ EF + PELAL+R V + D+ + Sbjct: 516 YTKVGIAGVPADSLMK-KTKAVEDD-WTPTWNEEFEFPLTAPELALLRIEVHEYDMSEKD 573 Query: 1157 NFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 +F GQ P+ LR G R+VPL N E+ L++ + Sbjct: 574 DFGGQTCLPVSELRTGIRAVPLHNQKGEKYNSVKLLMRFEFV 615 Score = 111 bits (266), Expect = 1e-22 Identities = 76/219 (34%), Positives = 112/219 (51%), Gaps = 13/219 (5%) Query: 229 YSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQR-DIYE--PYF 283 ++ Y G ++L + Q FL + Q G+DE Q I D L + + I++ Sbjct: 76 FNDYSEQGV-MSLEQLQKFLIEVQ----GEDEASMEDVQGIMDSLHEFKHLPIFQLRKGL 130 Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 L F L N S ++ V DM PLSHY+I + HN+YLTG+Q SS S + Sbjct: 131 NLEAFFRYLCHDLNPPL-SPHNTVHHDMNAPLSHYFIYTGHNSYLTGNQLSSICSDVPVI 189 Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402 L+ G R IELD W + HG TLTT ++ L +IK++AF+ SEYP+I+++ Sbjct: 190 NSLQCGVRVIELDMWPNSTKDDIDVLHGRTLTTPVKLSKCLISIKKYAFVASEYPVIITL 249 Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 ED+ + Q ++A +FGDLL P + PSP Sbjct: 250 EDHLTPDLQAKVAEMATQIFGDLLF-SPESECLAEFPSP 287 >UniRef50_P93620 Cluster: Phosphoinositide-specific phospholipase C; n=2; Vigna|Rep: Phosphoinositide-specific phospholipase C - Vigna unguiculata (Cowpea) Length = 549 Score = 124 bits (299), Expect = 1e-26 Identities = 72/219 (32%), Positives = 120/219 (54%), Gaps = 9/219 (4%) Query: 224 DIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRDIYEPYF 283 D+ +S + ++++ FL + Q + D V S+ I L+ +++ E F Sbjct: 26 DVQKAFSEFSDGASSMSAEHLLRFLAEHQGEV--DCTVSDSEQI---LQQSRKEDGETGF 80 Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 L +F L ++N + +V DM P+SHY+I + HN+YLTG+Q SS+ S + Sbjct: 81 DLHDFFHFL--QENDLNVPLKSQVHHDMNAPISHYFIYTGHNSYLTGNQLSSDCSDAPII 138 Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402 + L+ G R IELD W + + HG TLTT + + L++IKE+AF+ S+YPL++++ Sbjct: 139 KALQRGVRVIELDLWPNSNKDDIDVVHGRTLTTPVSLLRCLKSIKEYAFVKSQYPLVITL 198 Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 ED+ + Q ++A VFG+ LL +P + T PSP Sbjct: 199 EDHLTPDLQAKVAKMATQVFGE-LLHYPQTDSLTEFPSP 236 Score = 117 bits (282), Expect = 2e-24 Identities = 70/201 (34%), Positives = 111/201 (55%), Gaps = 11/201 (5%) Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 V++ + R+YPKG R++SSNY P W G+QMVA N Q K + G F+ NGGC Sbjct: 332 VRFTHNNILRVYPKGTRLNSSNYKPHIGWTYGAQMVAFNMQGHGKSLWYMQGMFRSNGGC 391 Query: 1046 GFILKPQFMFEEG-----YNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASP---F 1097 G++ KP F+ ++G ++P ++ +K V V L + + + SP + Sbjct: 392 GYVKKPNFLIQKGPQDEVFDPKIALPVKKTLK-VKVYLGKGWSLDFSPSDFDSYSPPDFY 450 Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157 V+V I+G D +K T +S+N P+WN+ +F + PELAL+ V+++D + + Sbjct: 451 VKVCIVGVPADM-IKKKTSVISNNWF-PVWNEEFDFPLTVPELALLGIEVREDDKHQKDD 508 Query: 1158 FIGQATFPLLCLRKGYRSVPL 1178 F GQ P+ L+ G+RSVPL Sbjct: 509 FGGQTCLPVSELKSGFRSVPL 529 >UniRef50_UPI0000F1F9F9 Cluster: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154); n=1; Danio rerio|Rep: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (Phosphoinositide phospholipase C) (Phospholipase C-beta-1) (PLC-beta-1) (PLC-I) (PLC-154) - Danio rerio Length = 354 Score = 123 bits (297), Expect = 3e-26 Identities = 76/198 (38%), Positives = 117/198 (59%), Gaps = 14/198 (7%) Query: 936 KEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLS 994 +E+S+L+ Y + V F N E + Y EMSSF ETKA L+ + F++Y+ QLS Sbjct: 100 EEMSNLVNYVQPVKFTNFETCKKVNRSY-EMSSFVETKAMDLLKESP-VEFIEYNKLQLS 157 Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFM 1054 RIYPKG R+DSSNYNP FWN G Q+VALN+QT + + + C +LKP+FM Sbjct: 158 RIYPKGTRVDSSNYNPQVFWNAGCQLVALNFQT----LGIFCPRLSAYCVCVCVLKPEFM 213 Query: 1055 --FEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVK 1112 ++ ++P + +++G + T+ L++I + L + G +VEVE+IG D+ K Sbjct: 214 RRMDKQFDPFTQSTVDGIIAH-TLSLKIISGQFLSEKRVGV---YVEVEMIGLPVDTRWK 269 Query: 1113 LV-TKTVSDNGLNPLWND 1129 TK+ N +NP+W++ Sbjct: 270 AFRTKSSQGNAINPVWDE 287 >UniRef50_Q762E2 Cluster: Phosphoinositide-specific phospholipase C; n=1; Physcomitrella patens|Rep: Phosphoinositide-specific phospholipase C - Physcomitrella patens (Moss) Length = 639 Score = 123 bits (297), Expect = 3e-26 Identities = 60/151 (39%), Positives = 88/151 (58%), Gaps = 1/151 (0%) Query: 281 PYFTLSEFVEMLYSKQNSIYDSQYDKV-TQDMTRPLSHYWISSSHNTYLTGDQFSSESSL 339 P F ++ F++ L + + + K T DM PLS Y+I SSHNTYL G+Q S SS Sbjct: 119 PTFDIATFLKFLLHPEFNGHRVPVSKTPTDDMNAPLSDYYIFSSHNTYLMGNQLCSPSST 178 Query: 340 EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLI 399 V+ L GCR IELDCW+G + + HG TLT + F D ++ IK++AF TS YP++ Sbjct: 179 APIVKALLDGCRVIELDCWNGSNKRIDVLHGGTLTKAVPFEDCVKAIKDNAFTTSAYPVV 238 Query: 400 LSIEDNCSLPQQRRMASAFQDVFGDLLLVHP 430 ++IE + L Q+ A + G+++ V P Sbjct: 239 VTIESHLDLEHQKEAARVLNKILGNIMFVPP 269 Score = 98.3 bits (234), Expect = 1e-18 Identities = 64/223 (28%), Positives = 113/223 (50%), Gaps = 8/223 (3%) Query: 965 MSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALN 1024 M++ E++ + L+ ++ +++ T L+R+YP G R+ SSN +P+ W G Q+ A+N Sbjct: 407 MANLSESQLDDLIEDHTDSL-IEFSKTNLTRVYPFGLRVTSSNADPMDAWEHGVQVAAIN 465 Query: 1025 YQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGAR 1084 Q D+P+ ++ F +NGGCG++ KP + E + D KS+ + + + V+ Sbjct: 466 MQGRDRPVWISKAIFSRNGGCGYVKKPDILLPE--SNMDHKSLMNLQPKLELKVTVLLGT 523 Query: 1085 HLCKTGRGTASP--FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWN-DICEFEVANPELA 1141 K P FV+V I G +D K T V P W + F++ P+LA Sbjct: 524 DWHKNYDVFKKPGYFVKVAIHGM-HDDEQKFKTH-VCKRSREPHWEVEEFVFQIRVPKLA 581 Query: 1142 LIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184 ++R V++ D + +GQ+ P+ R+G R+V L + E Sbjct: 582 ILRLEVREYDRIVRDDMVGQSCVPVTEHRQGIRAVQLASKKGE 624 >UniRef50_Q56W08 Cluster: Phosphoinositide-specific phospholipase C; n=6; core eudicotyledons|Rep: Phosphoinositide-specific phospholipase C - Arabidopsis thaliana (Mouse-ear cress) Length = 564 Score = 123 bits (296), Expect = 3e-26 Identities = 80/226 (35%), Positives = 119/226 (52%), Gaps = 7/226 (3%) Query: 977 MSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNM 1036 M + T V++ L RIYPKG R+DSSNY+P W G+QMVA N Q K + + Sbjct: 334 MVRTRGTDLVRFTQRNLVRIYPKGTRVDSSNYDPHVGWTHGAQMVAFNMQGHGKQLWIMQ 393 Query: 1037 GKFKQNGGCGFILKPQFMFEEG--YNPCDKKSIEG--KVKPVTVMLRVIGARHLCKTGRG 1092 G F+ NGGCG++ KP+ + +E ++PC + I+ KVK T + H Sbjct: 394 GMFRGNGGCGYVKKPRILLDEHTLFDPCKRFPIKTTLKVKIYTGEGWDLDFHHTHFDQYS 453 Query: 1093 TASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLW-NDICEFEVANPELALIRFVVQDED 1151 FV++ I G D+ V T+T D P+W ND F+++ PELAL+ F VQD D Sbjct: 454 PPDFFVKIGIAGVPRDT-VSYRTETAVDQWF-PIWGNDEFLFQLSVPELALLWFKVQDYD 511 Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 + +F GQ PL L+ G R+V L + + + + L+V ++ Sbjct: 512 NDTQNDFAGQTCLPLPELKSGVRAVRLHDRTGKAYKNTRLLVSFAL 557 Score = 107 bits (256), Expect = 2e-21 Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 3/160 (1%) Query: 285 LSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVR 344 L+ F L+S NS +V DM PLSHY++ + HN+YLTG+Q +S SS+E V+ Sbjct: 83 LNAFYRYLFSDTNSPLPMS-GQVHHDMKAPLSHYFVYTGHNSYLTGNQVNSRSSVEPIVQ 141 Query: 345 CLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIE 403 LR G + IELD W P G + HG TLT+ L IK++AF S+YP+I+++E Sbjct: 142 ALRKGVKVIELDLWPNPSGNAAEVRHGRTLTSHEDLQKCLTAIKDNAFHVSDYPVIITLE 201 Query: 404 DNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 D+ Q ++A + +L + ++ PSP + Sbjct: 202 DHLPPKLQAQVAKMLTKTYRGMLF-RRVSESFKHFPSPEE 240 >UniRef50_Q8GV43 Cluster: Phosphoinositide-specific phospholipase C 8; n=28; Magnoliophyta|Rep: Phosphoinositide-specific phospholipase C 8 - Arabidopsis thaliana (Mouse-ear cress) Length = 544 Score = 122 bits (293), Expect = 8e-26 Identities = 78/235 (33%), Positives = 123/235 (52%), Gaps = 12/235 (5%) Query: 967 SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026 S E + +R S V++ L RIYPKG R +SSNY P+ W G+QM+A N Q Sbjct: 309 SLSEQELDRTCSSNSQDV-VRFTQRNLLRIYPKGTRFNSSNYKPLIGWTHGAQMIAFNMQ 367 Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEG-----YNPCDKKSIEGKVKPVTVMLRVI 1081 K + + G F+ NGGCG++ KP F+ ++G ++P K ++ +K V V + Sbjct: 368 GYGKSLWLMHGMFRANGGCGYVKKPNFLMKKGFHDEVFDPRKKLPVKETLK-VKVYMGDG 426 Query: 1082 GARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANP 1138 T SP + ++ I+G D+ K TK + DN P+W++ F + P Sbjct: 427 WRMDFSHTHFDAYSPPDFYTKMFIVGVPADN-AKKKTKIIEDNWY-PIWDEEFSFPLTVP 484 Query: 1139 ELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMV 1193 ELAL+R V++ D+ + +F GQ P+ LR G RSVPL + E+++ L++ Sbjct: 485 ELALLRIEVREYDMSEKDDFGGQTCLPVAELRPGIRSVPLYDKKGEKMKSVRLLM 539 Score = 117 bits (282), Expect = 2e-24 Identities = 57/136 (41%), Positives = 85/136 (62%), Gaps = 2/136 (1%) Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366 V QDMT PLSHY+I + HN+YLTG+Q SS+ S ++ L+ G R IELD W GT Sbjct: 66 VHQDMTAPLSHYFIYTGHNSYLTGNQLSSDCSEVPVIKALQRGVRVIELDLWPNSTGTDI 125 Query: 367 -IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425 + HG TLTT + M L++I+++AF +S YP+I+++ED+ + Q ++A +FG Sbjct: 126 NVLHGRTLTTPVPLMKCLKSIRDYAFSSSPYPVIITLEDHLTPDLQAKVAEMATQIFGQ- 184 Query: 426 LLVHPMDKNETSLPSP 441 +L +P + PSP Sbjct: 185 MLYYPESDSLLEFPSP 200 >UniRef50_UPI0000E493BE Cluster: PREDICTED: similar to ENSANGP00000003004, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to ENSANGP00000003004, partial - Strongylocentrotus purpuratus Length = 354 Score = 120 bits (289), Expect = 2e-25 Identities = 73/210 (34%), Positives = 117/210 (55%), Gaps = 24/210 (11%) Query: 1002 RIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNP 1061 RIDSSNYNP +W+ G Q+VALNYQT D +Q F++ G CG++LKP +++ + Sbjct: 2 RIDSSNYNPFIYWSFGVQLVALNYQTDDPSLQTYFAMFERTGNCGYVLKPTILWDRNHPA 61 Query: 1062 CDK-----KSIEG-KVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGADYDSGVKLVT 1115 ++ KS +G +K +T+ +++ + L T S FVEVE++G D K T Sbjct: 62 FNRFNAYNKSFDGMPIKELTI--QIVSGQFLSLT-NPLGSVFVEVEVMGIPADC-AKWKT 117 Query: 1116 KTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRK---- 1171 K S N +NP+W + F+V+ +LA +RF V D + + + Q + PL+ LR+ Sbjct: 118 KIASRNSINPIWEETFTFQVSFEDLAFVRFTVIDSN---SSSTLAQRSVPLVHLRQDKDG 174 Query: 1172 -------GYRSVPLTNAFSEELELSTLMVH 1194 GYR + L ++ + LE++TL +H Sbjct: 175 DNAIDLTGYRHLRLRSSQNIPLEITTLFIH 204 >UniRef50_A7T500 Cluster: Predicted protein; n=4; cellular organisms|Rep: Predicted protein - Nematostella vectensis Length = 171 Score = 118 bits (285), Expect = 7e-25 Identities = 76/181 (41%), Positives = 103/181 (56%), Gaps = 23/181 (12%) Query: 1021 VALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV 1080 VALNYQT + +Q+N GKF+ NG CG++LKP + C K EG+ + L Sbjct: 1 VALNYQTEGRMLQINRGKFRANGNCGYVLKPDIL-------C-KGMTEGEGEGGYQTLY- 51 Query: 1081 IGARHLCK---TGRGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVAN 1137 +LCK G G P+VEVEIIG D+ K TKTV DNG NP+W + F + Sbjct: 52 ----NLCKGMTEGGGIIDPYVEVEIIGIPADTS-KYRTKTVIDNGFNPVWEETMVFLLNF 106 Query: 1138 PELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 P++AL+RFVV DED G +FIGQ T P + G+R V L E L+ +T+ H++I Sbjct: 107 PDIALVRFVVWDEDPIGR-DFIGQMTLPFQSIMPGFRHVHL-----EGLDQATVFCHVTI 160 Query: 1198 I 1198 + Sbjct: 161 M 161 >UniRef50_Q4YWB8 Cluster: Phospholipase C-like, putative; n=4; Plasmodium (Vinckeia)|Rep: Phospholipase C-like, putative - Plasmodium berghei Length = 1312 Score = 118 bits (284), Expect = 1e-24 Identities = 66/165 (40%), Positives = 94/165 (56%), Gaps = 5/165 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 Y T V L SK+NSI +Y KV Q+M PL +YWI+SSHN+YL+ Q S SS+E Sbjct: 553 YLTQIGLVYFLLSKENSIMCPEYAKVYQNMNLPLCNYWINSSHNSYLSRKQIFSASSIEQ 612 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 Y+ L GCRC+E DC+ + +YH G+ LT+ I F D L K F TS YP+ Sbjct: 613 YIYILIDGCRCVEFDCYYF-NKNIVVYHGLYGYKLTSSILFCDTLIACKMFGFSTSPYPI 671 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 ILS+E +C + +A + G+ L + P K+E + +P++ Sbjct: 672 ILSLEIHCKDKHKNLIAKILIYILGNQLYI-PKTKDEINNITPNN 715 Score = 89.0 bits (211), Expect = 7e-16 Identities = 42/95 (44%), Positives = 62/95 (65%), Gaps = 3/95 (3%) Query: 962 YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021 YNE+ S E K +L+ + E+ +KY+ L+R+YP G R+ S+N+NP+ FW+ G Q V Sbjct: 950 YNEICSISENKFIKLIKKHEDDV-IKYNQKTLTRVYPSGTRLASTNFNPLIFWSAGIQFV 1008 Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054 ALNYQ M +N G+F +NGG G+ILKP+ + Sbjct: 1009 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPELL 1043 >UniRef50_Q944C1 Cluster: Phosphoinositide-specific phospholipase C; n=8; Magnoliophyta|Rep: Phosphoinositide-specific phospholipase C - Arabidopsis thaliana (Mouse-ear cress) Length = 597 Score = 117 bits (281), Expect = 2e-24 Identities = 82/284 (28%), Positives = 133/284 (46%), Gaps = 10/284 (3%) Query: 198 EKRGEIGFDDFAVLY-QKLIFDENN-VQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDN 255 E + E+G F +++ +K E+ V+D+ D + Y ++ + Q + +E + Sbjct: 2 EGKKEMGSYKFCLIFTRKFRMTESGPVEDVRDLFEKYTEGDAHMSPEQLQKLMTEEGGEG 61 Query: 256 LGDDEVQASQFIRDYLRDPQR--DIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTR 313 E +A + + + LR TL +F L+S + D+V Q+M Sbjct: 62 ETSLE-EAERIVDEVLRRKHHIAKFTRRNLTLDDFNYYLFS--TDLNPPIADQVHQNMDA 118 Query: 314 PLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTL 373 PLSHY+I + HN+YLTG+Q SS S LR G R +ELD W + HG TL Sbjct: 119 PLSHYFIFTGHNSYLTGNQLSSNCSELPIADALRRGVRVVELDLWPRGTDDVCVKHGRTL 178 Query: 374 TTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDK 433 T +++ L +IK +AF S+YP+I+++ED+ + Q ++A FGD+L H + Sbjct: 179 TKEVKLGKCLESIKANAFAISKYPVIITLEDHLTPKLQFKVAKMITQTFGDMLYYHD-SQ 237 Query: 434 NETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQ--EEGKDLD 475 PSP + E E + + E+GKD D Sbjct: 238 GCQEFPSPEELKEKILISTKPPKEYLEANDTKEKDNGEKGKDSD 281 Score = 116 bits (278), Expect = 5e-24 Identities = 75/220 (34%), Positives = 111/220 (50%), Gaps = 9/220 (4%) Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 +++ RIYPKG R +SSNY P W G+QM+A N Q + + + G F+ NGGC Sbjct: 380 IRFTQKNFLRIYPKGTRFNSSNYKPQIGWMSGAQMIAFNMQGYGRALWLMEGMFRANGGC 439 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV-IGARHLC---KTGRGTASP---FV 1098 G++ KP F+ + N D + T+ ++V +G L KT + SP FV Sbjct: 440 GYVKKPDFLMDASPNGQDFYPKDNSSPKKTLKVKVCMGDGWLLDFKKTHFDSYSPPDFFV 499 Query: 1099 EVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNF 1158 V I GA D V TK D P+WN F +A PELAL+R V + D+ + +F Sbjct: 500 RVGIAGAPVDE-VMEKTKIEYDT-WTPIWNKEFTFPLAVPELALLRVEVHEHDVNEKDDF 557 Query: 1159 IGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 GQ P+ +R+G R+VPL N + + L++ + Sbjct: 558 GGQTCLPVSEIRQGIRAVPLFNRKGVKYSSTRLLMRFEFV 597 >UniRef50_Q9LUZ0 Cluster: Phosphoinositide-specific phospholipase C-line; n=37; Magnoliophyta|Rep: Phosphoinositide-specific phospholipase C-line - Arabidopsis thaliana (Mouse-ear cress) Length = 909 Score = 116 bits (280), Expect = 3e-24 Identities = 72/207 (34%), Positives = 104/207 (50%), Gaps = 9/207 (4%) Query: 978 SQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037 ++ T +K+ L RIYPK R++SSNY P W G+QMVA N Q + + + G Sbjct: 353 TEMYGTEVIKFTQKNLLRIYPKATRVNSSNYRPYNGWMYGAQMVAFNMQGYGRALWMMHG 412 Query: 1038 KFKQNGGCGFILKPQFMFE-----EGYNPCDKKSIEGKVKPVTVMLR--VIGARHLCKTG 1090 F+ NGGCG++ KP FM E +NP K I+ +K M + G + C Sbjct: 413 MFRGNGGCGYVKKPDFMMNNNLSGEVFNPKAKLPIKKTLKVKVYMGKGWDSGFQRTCFNT 472 Query: 1091 RGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDE 1150 + + + V I G D +K K P WN+ EF++ PELAL+R V D Sbjct: 473 WSSPNFYTRVGITGVRGDKVMKKTKK--EQKTWEPFWNEEFEFQLTVPELALLRIEVHDY 530 Query: 1151 DIFGEPNFIGQATFPLLCLRKGYRSVP 1177 ++ + +F GQ P+ LR+G RSVP Sbjct: 531 NMPEKDDFSGQTCLPVSELRQGIRSVP 557 Score = 113 bits (272), Expect = 3e-23 Identities = 65/163 (39%), Positives = 92/163 (56%), Gaps = 10/163 (6%) Query: 285 LSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 L +F L+S N DS KV QDM PLSHY+I +SHN+YLTG+Q +SE S + Sbjct: 90 LDDFFSFLFSDDLNHPIDS---KVHQDMASPLSHYFIYTSHNSYLTGNQINSECSDVPLI 146 Query: 344 RCLRSGCRCIELDCWDGPDGTP---FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLIL 400 + L+ G R +ELD W P+ T + HG T + + LR+IKEHAF S YP+IL Sbjct: 147 KALKRGVRALELDMW--PNSTKDDILVLHGWAWTPPVELVKCLRSIKEHAFYASAYPVIL 204 Query: 401 SIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 ++ED+ + Q + A +++F D ++ P PSP D Sbjct: 205 TLEDHLTPDLQAKAAEMMKEIFMD-MVYFPEAGGLKEFPSPED 246 >UniRef50_A5K7G0 Cluster: Phospholipase C-like, putative; n=3; Plasmodium|Rep: Phospholipase C-like, putative - Plasmodium vivax Length = 1432 Score = 116 bits (280), Expect = 3e-24 Identities = 64/165 (38%), Positives = 93/165 (56%), Gaps = 5/165 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 Y T V L SK+NSI +Y KV Q+M PL +YWI+SSHNTYL Q S S++E Sbjct: 615 YLTQIGLVYFLLSKENSIMCPEYSKVYQNMNLPLCNYWINSSHNTYLGRKQIFSSSNIEQ 674 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 Y+ L GCRC+E DC+ + +YH G+ LT+ I F D L K F TS +P+ Sbjct: 675 YIYILIDGCRCVEFDCYYF-NKNIVVYHGFYGYKLTSSILFCDTLIACKLFGFTTSPFPI 733 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 ILS+E +C + +A + G+ L + P ++E + +P++ Sbjct: 734 ILSLEIHCKNKHKNLIAKILICILGNQLYI-PKSRDEINNITPNN 777 Score = 89.0 bits (211), Expect = 7e-16 Identities = 42/95 (44%), Positives = 61/95 (64%), Gaps = 3/95 (3%) Query: 962 YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021 YNE+ S E K +L+ + E +KY+ L+R+YP G R+ S+N+NP+ FW+ G Q V Sbjct: 1039 YNEICSISENKFIKLIKKNEEEI-IKYNQKTLTRVYPSGTRLASTNFNPLIFWSAGIQFV 1097 Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054 ALNYQ M +N G+F +NGG G+ILKP+ + Sbjct: 1098 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPEIL 1132 Score = 50.0 bits (114), Expect = 4e-04 Identities = 29/81 (35%), Positives = 48/81 (59%), Gaps = 3/81 (3%) Query: 1123 LNPLWN--DICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTN 1180 LN W+ I + ++ P LALI F ++ D + I A FP+ CLR+G R VPL + Sbjct: 1352 LNYCWSKPSIFQMKITYPSLALIVFELKTYDTV-KSELIACACFPVKCLREGIRFVPLCD 1410 Query: 1181 AFSEELELSTLMVHLSIITDG 1201 + ++++ S ++V+L I T+G Sbjct: 1411 KYLKDIKGSGILVNLKIGTNG 1431 >UniRef50_Q8IJR0 Cluster: Phospholipase C-like, putative; n=1; Plasmodium falciparum 3D7|Rep: Phospholipase C-like, putative - Plasmodium falciparum (isolate 3D7) Length = 1357 Score = 116 bits (279), Expect = 4e-24 Identities = 64/165 (38%), Positives = 92/165 (55%), Gaps = 5/165 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 Y T V L SK+NSI +Y KV Q+M PL +YWI+SSHN+YL Q S S++E Sbjct: 597 YLTEIGLVYFLLSKENSIMCPEYAKVYQNMNLPLCNYWINSSHNSYLARKQIFSTSNIEQ 656 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYH---GHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 Y+ L GCRC+E DC+ + +YH G+ LT+ I F D L K F TS YP+ Sbjct: 657 YIYILLDGCRCVEFDCYYF-NKNIVVYHGFYGYKLTSSILFCDTLIACKMFGFTTSPYPI 715 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 ILS+E +C + +A + G+ L + P +E + +P++ Sbjct: 716 ILSLEIHCKNKHKNLIAKILISILGNQLYI-PKTTDEINNITPNN 759 Score = 93.9 bits (223), Expect = 2e-17 Identities = 44/95 (46%), Positives = 63/95 (66%), Gaps = 3/95 (3%) Query: 962 YNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMV 1021 YNE+ S E K +L+ + EN +KY+ L+R+YP G R+ S+N+NP+ FWN G Q+V Sbjct: 993 YNEICSISENKFIKLIKKNENEI-IKYNQKTLTRVYPSGTRLASTNFNPLIFWNAGIQVV 1051 Query: 1022 ALNYQTPDKPMQVNMGKFKQNGG--CGFILKPQFM 1054 ALNYQ M +N G+F +NGG G+ILKP+ + Sbjct: 1052 ALNYQYNGLSMLLNKGRFLENGGKHSGYILKPELL 1086 >UniRef50_A5AGR6 Cluster: Putative uncharacterized protein; n=1; Vitis vinifera|Rep: Putative uncharacterized protein - Vitis vinifera (Grape) Length = 592 Score = 116 bits (278), Expect = 5e-24 Identities = 75/213 (35%), Positives = 107/213 (50%), Gaps = 24/213 (11%) Query: 986 VKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGC 1045 +++ L R++PK R+DSSNYNP+ W G+QMVA N Q D+P+ + G F+ NGGC Sbjct: 404 IRFTQRNLLRVFPKVMRVDSSNYNPLIGWMHGAQMVAFNMQGYDRPLWLMQGMFRANGGC 463 Query: 1046 GFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLCKTGRGTASPFVEVEIIGA 1105 G++ KP + + G P DK PV L+ V I G Sbjct: 464 GYVKKPDLLLKVG--PHDKVFDPKANLPVKTTLK--------------------VGIAGV 501 Query: 1106 DYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFP 1165 DS +K TK V D+ P WN+ EF + PELAL+R V + D+ + +F GQ P Sbjct: 502 PADSLMK-KTKAVEDD-WTPTWNEEFEFPLTAPELALLRIEVHEYDMSEKDDFGGQTCLP 559 Query: 1166 LLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 + LR G R+VPL N E+ L++ + Sbjct: 560 VSELRTGIRAVPLHNQKGEKYNSVKLLMRFEFV 592 Score = 111 bits (266), Expect = 1e-22 Identities = 76/219 (34%), Positives = 112/219 (51%), Gaps = 13/219 (5%) Query: 229 YSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQAS--QFIRDYLRDPQR-DIYE--PYF 283 ++ Y G ++L + Q FL + Q G+DE Q I D L + + I++ Sbjct: 31 FNDYSEEGV-MSLEQLQKFLIEVQ----GEDEASMEDVQGIMDSLHEFKHLPIFQLRKGL 85 Query: 284 TLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYV 343 L F L N S ++ V DM PLSHY+I + HN+YLTG+Q SS S + Sbjct: 86 NLEAFFRYLCHDLNPPL-SPHNTVHHDMNAPLSHYFIYTGHNSYLTGNQLSSICSDVPVI 144 Query: 344 RCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402 L+ G R IELD W + HG TLTT ++ L +IK++AF+ SEYP+I+++ Sbjct: 145 NSLQCGVRVIELDMWPNSTKDDIDVLHGRTLTTPVKLSKCLISIKKYAFVASEYPVIITL 204 Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 ED+ + Q ++A +FGDLL P + PSP Sbjct: 205 EDHLTPDLQAKVAEMATQIFGDLLF-SPESECLAEFPSP 242 >UniRef50_Q9AXF1 Cluster: Phosphoinositide-specific phospholipase C; n=3; Oryza sativa|Rep: Phosphoinositide-specific phospholipase C - Oryza sativa (Rice) Length = 599 Score = 114 bits (275), Expect = 1e-23 Identities = 64/162 (39%), Positives = 90/162 (55%), Gaps = 3/162 (1%) Query: 284 TLSEFVEMLYSKQ-NSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342 T+ +F L+S + N +V DM PLSHY+I + HN+YLTG+Q SS+ S Sbjct: 89 TVDDFHRFLFSHELNPPIRHGQGQVHHDMAAPLSHYFIYTGHNSYLTGNQLSSDCSDLPI 148 Query: 343 VRCLRSGCRCIELDCWDGPDGTPF-IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILS 401 +R L+ G R IELD W I HG T TT + + L +IKEHAF S YP+I++ Sbjct: 149 IRALQRGVRVIELDMWPNSSKDDISILHGRTPTTPVSLLKCLLSIKEHAFEASPYPVIIT 208 Query: 402 IEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSPHD 443 +ED+ + Q + A +VFGD +L +P + PSP D Sbjct: 209 LEDHLTPDLQDKAAKMVLEVFGD-ILYYPDKDHLKEFPSPQD 249 Score = 113 bits (271), Expect = 4e-23 Identities = 79/234 (33%), Positives = 117/234 (50%), Gaps = 15/234 (6%) Query: 958 KGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ--------LSRIYPKGQRIDSSNYN 1009 KG + + + S PE +S+Q+ +H T+ L RIYPKG R+ SSNYN Sbjct: 348 KGTLLDALQSDPEKVRRLSLSEQQLAKLADHHGTEIVRFTQRNLLRIYPKGTRVTSSNYN 407 Query: 1010 PVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCD-KKSIE 1068 P W G+QMVA N Q + + + G +K NGGCG++ KP F+ + D KKS+ Sbjct: 408 PFLGWVHGAQMVAFNMQGYGRALWLMHGFYKANGGCGYVKKPDFLMQTDPEVFDPKKSLS 467 Query: 1069 G-KVKPVTVMLRVIGARHLCKTGRGTASP---FVEVEIIGADYDSGVKLVTKTVSDNGLN 1124 K V V + +T SP + V I G DS +K T+ + DN + Sbjct: 468 SKKTLKVKVYMGDGWRMDFTQTHFDQYSPPDFYARVGIAGVPADSVMKR-TRAIEDNWV- 525 Query: 1125 PLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 P+W + F++ PE+AL+R V + D+ + +F GQ P+ L G R+V L Sbjct: 526 PVWEEDFTFKLTVPEIALLRVEVHEYDMSEKDDFGGQTVLPVSELIPGIRAVAL 579 >UniRef50_A6RM87 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 1023 Score = 113 bits (273), Expect = 2e-23 Identities = 90/283 (31%), Positives = 140/283 (49%), Gaps = 35/283 (12%) Query: 165 EKITLKEVKAFLPKINCKISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQD 224 E + + V+ ++ S+ LR+ FQ D K ++ F +F + KL+ +V + Sbjct: 399 EALDFEGVEQLCKNLHINTSSRFLRERFQQADATKSKKLIFSEFQE-FVKLMKRRGDVSE 457 Query: 225 IFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQ-ASQFIRDYLRDPQRD--IYEP 281 I+ + + N ITL EF +F+ Q +N+ D + S F + R RD + E Sbjct: 458 IYRELA--SDNVKGITLEEFIDFVNVVQGENVEKDRAKWESIFAKFARRSRSRDQPLQEG 515 Query: 282 YFT-LSEFVEMLYSKQNSIYDSQYDKVTQDMT--RPLSHYWISSSHNTYLTGDQFSSESS 338 +SE E L + S+++ + V + T RP+ Y+ISSSHNTYL G Q + ESS Sbjct: 516 EAARMSE--EALATFFTSVHNVPLETVPETFTLDRPMHEYFISSSHNTYLMGRQVAGESS 573 Query: 339 LEAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPL 398 +EAY+ L GCR I F DV+ TI ++AF+ S +PL Sbjct: 574 VEAYISALIKGCR------------------------PIMFSDVMYTIAKYAFVKSHFPL 609 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETSLPSP 441 +S+E +C+ QQ MA ++ GDLL+ P+D + LPSP Sbjct: 610 WISLEVHCNDAQQAAMAQIIKEACGDLLVTEPLDPSSQVLPSP 652 Score = 41.1 bits (92), Expect = 0.18 Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 6/89 (6%) Query: 1115 TKTVSDNGLNPLWNDICEFEVAN--PELALIRFVVQ---DEDIFGEPNF-IGQATFPLLC 1168 T V +NG NP++N F + PEL +R+ V+ D + + + T L Sbjct: 892 THIVQENGFNPVFNKKFNFALTTKFPELVFVRWTVRCSSDGHSYNDKTLPLATYTAKLSS 951 Query: 1169 LRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 L++GYR++PL + ++ STL + I Sbjct: 952 LKQGYRTLPLYDTNGDQFLFSTLFCRVKI 980 >UniRef50_Q9XWB7 Cluster: Putative uncharacterized protein plc-2; n=2; Caenorhabditis|Rep: Putative uncharacterized protein plc-2 - Caenorhabditis elegans Length = 896 Score = 110 bits (265), Expect = 2e-22 Identities = 80/230 (34%), Positives = 117/230 (50%), Gaps = 19/230 (8%) Query: 217 FDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDN-LGDDEVQ--ASQFIRDYLRD 273 F+ + ++ IF K S + T EF ++LR QHD+ L D + + I L + Sbjct: 211 FEGSRLEAIFRKIS---EDEPVATKLEFGDWLRKNQHDHRLNDARFNQVSDRKINSILEN 267 Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSI-YDSQYDKV-TQDMTRPLSHYWISSSHNTYLTGD 331 Q + + F + S + + +Q K+ M P++ Y+I+SSHNTY +G+ Sbjct: 268 WQYSS-DSAISPQMFTHWMVSDECGVAISAQRMKMDVTSMREPINKYFINSSHNTYCSGN 326 Query: 332 QF-----SSESSLEAYVRCLRSGCRCIELDCWDGPD--GTPFIYHGHTLT---TKIRFMD 381 Q + +E Y + L SG RC+ELD WD D G P I HG T +I + Sbjct: 327 QLVYAIGHCSADVEMYRQALLSGSRCVELDMWDNKDKDGEPVITHGPTAVMGMNEIGLKE 386 Query: 382 VLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPM 431 V IKE AF TS YP+ILSIE++ QQ +M F+ VFG+LLL P+ Sbjct: 387 VCEAIKECAFKTSPYPVILSIENHLGRKQQEKMVQIFRQVFGELLLTGPL 436 Score = 79.0 bits (186), Expect = 7e-13 Identities = 33/64 (51%), Positives = 47/64 (73%) Query: 991 TQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILK 1050 ++++RIYPK RI S+NYNP+ W GSQMV+LN QT MQ+N F++NGGCG++ K Sbjct: 587 SKITRIYPKASRIYSTNYNPMIHWLTGSQMVSLNIQTNCSNMQLNYAMFERNGGCGYVRK 646 Query: 1051 PQFM 1054 P ++ Sbjct: 647 PDWL 650 >UniRef50_Q236T7 Cluster: Phosphatidylinositol-specific phospholipase C, X domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Phosphatidylinositol-specific phospholipase C, X domain containing protein - Tetrahymena thermophila SB210 Length = 1278 Score = 109 bits (263), Expect = 3e-22 Identities = 105/414 (25%), Positives = 190/414 (45%), Gaps = 55/414 (13%) Query: 67 EGALDIRDVKEVRTGKSSKDFERWPEETKRLESSKCFTIYYGTEFKLRCASFVAQTDKEC 126 E + + ++K +++ S + + S C T+ G E L K Sbjct: 105 ESRIKLSEIKNIQSKPSLTEINNYDSSV-----SLCLTMDGGFELILEF-----NDKKTR 154 Query: 127 EAWVKGVLYLIAEAVSASYPLQI----ERWLRKEFYSIE-NSHEKITLKEVKAFLPKINC 181 + W KG+L++ + Y +Q E+++ + E + +KIT KEVK L K+ Sbjct: 155 DKWWKGLLFV--KEYGPDYDIQNYQTKEQFIAQLLLGAEIDKKKKITDKEVKKLLRKLLI 212 Query: 182 KISTSKLRDVFQDVDTEKRGEIGFDDFAVLYQKLIFDENNVQDIFDKYSVYCSNGTTITL 241 +I+ +L D + + +++F L L+ ++ +Q I Y YC+N I Sbjct: 213 QINNEELEDKIKKYYKNNEKSLTYNEFIELTITLL-EKPEIQPI---YQSYCTNNNMILQ 268 Query: 242 REFQNFLRDEQHDNLGDDEVQAS---------QFIRDYLR-------------DPQRDI- 278 ++ F ++EQ +N + +V + + + +YL DP + + Sbjct: 269 KDILKFYQNEQGENYDEKQVLSKMNKLTKGREKKMINYLSFCQLIFTGDNSIFDPAKQVI 328 Query: 279 ---YEPYFTLSEFVEMLYSKQNSIYD---SQ--YDKVTQDMTRPLSHYWISSSHNTYLTG 330 +E F L +FV++ +++ + + SQ + Q+M +PLS Y+I+SS +YL Sbjct: 329 SGLFEKDFNL-QFVQINFNQVFNTFQLISSQLFFQYTPQNMDKPLSDYFINSSFRSYLVY 387 Query: 331 DQFSSESSL-EAYVRCLRSGCRCIELDCWDGPDGTPFIYHGHTLTTKIRFMDVLRTIKEH 389 D + L +AY+ L+ G R +++ C DG G P G T + D+ + IK++ Sbjct: 388 DLVTQTKDLTKAYIYLLQKGVRHLDIYCQDGESGVPEALQGVFQVTPVSVEDIFKAIKQY 447 Query: 390 AFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSPH 442 F S YP+I+++E CS+ QQ +A +VF D+L P D LPSP+ Sbjct: 448 GFERSVYPIIINLEHECSVNQQNLIAQFLVNVFQDMLYRLPEDFISLDYLPSPN 501 Score = 101 bits (241), Expect = 2e-19 Identities = 72/228 (31%), Positives = 110/228 (48%), Gaps = 11/228 (4%) Query: 979 QQENTFFVKYHTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037 Q+E + HT Q L R YPK + D SNYN + G Q A+NY T D + + Sbjct: 1004 QEEMNQQIVNHTRQYLLRTYPKQAKSDHSNYNFLQTMVSGCQFSAMNYYTQDLYLLAYLQ 1063 Query: 1038 KFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKP-VTVMLRVIGARHLCKTG--RGTA 1094 FKQN CG++LKP ++ ++ + KP + + + +I A+ L G Sbjct: 1064 YFKQNASCGYVLKPPWLLSSTAKTSNQYFEKEASKPKIWLKVEIISAQSLRIPGDEEKIF 1123 Query: 1095 SPFVEVEIIGADYDSGVK---LVTKTVSDNG-LNPLW-NDICEFEVANPELALIRFVVQD 1149 SP++ + +IG D V+ V +N NP + N I +F V PELA + F V D Sbjct: 1124 SPYISIRLIGTALDIQANENLFVSNQVKNNSCYNPQFENCIADFTVYIPELAFVIFQVYD 1183 Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 + Q P+ C+RKG+R++PL ++ + S L H+SI Sbjct: 1184 NPECQDR--FAQYAIPVSCIRKGFRTIPLLDSQLNPIPNSFLFAHISI 1229 >UniRef50_UPI00015A74B5 Cluster: UPI00015A74B5 related cluster; n=1; Danio rerio|Rep: UPI00015A74B5 UniRef100 entry - Danio rerio Length = 573 Score = 108 bits (259), Expect = 1e-21 Identities = 75/207 (36%), Positives = 104/207 (50%), Gaps = 18/207 (8%) Query: 197 TEKRGEIGFDDFAV-LYQKL---IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQ 252 T + I D F +Y++L I N++ IF SV T ++ F EQ Sbjct: 117 TGRNDSIPLDTFTQDVYRQLLNNICPRNDIDTIFSDMSVLFILCTHCSV--LLGFAEREQ 174 Query: 253 HDNLGDDEVQASQFIRDYLRDPQRDIYEPYFTLSE--------FVEMLYSKQNSIYDSQY 304 H D + + ++ + YEP LS F L ++N I + Sbjct: 175 HMTEADTPLTXPHLKAEQVQ-ALVEKYEPDSMLSSRGQISVEGFARYLSGEENCIIPPEK 233 Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG--PD 362 +++D+T+PLSHY+I+SSHNTYL G Q + SS+E Y + L SGCRC+ELD W G PD Sbjct: 234 LDLSEDITQPLSHYFINSSHNTYLIGQQLAGTSSVEIYRQVLLSGCRCVELDVWKGKAPD 293 Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEH 389 P I HG T+TT+I F D L T K H Sbjct: 294 EEPIITHGFTMTTEISFKDTL-TTKAH 319 Score = 54.4 bits (125), Expect = 2e-05 Identities = 25/53 (47%), Positives = 35/53 (66%), Gaps = 2/53 (3%) Query: 977 MSQQENTFFVKYHTTQLSR--IYPKGQRIDSSNYNPVPFWNCGSQMVALNYQT 1027 + Q E + + H+T + ++ KG R+DSSNYNP FWN G Q+VALN+QT Sbjct: 520 VEQSEASPAEEQHSTSCTHTALWXKGTRVDSSNYNPQVFWNAGCQLVALNFQT 572 >UniRef50_A4S165 Cluster: Predicted protein; n=1; Ostreococcus lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 495 Score = 107 bits (257), Expect = 2e-21 Identities = 51/120 (42%), Positives = 69/120 (57%) Query: 311 MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPFIYHG 370 MT LSHY+++SSHNTYL G Q S S+ A L GCR +ELDC+DG P I HG Sbjct: 1 MTDELSHYFVNSSHNTYLDGGQLFSRSTSSAIAWALERGCRVVELDCYDGGSKGPIITHG 60 Query: 371 HTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLLLVHP 430 T + F D + I + A + SEYP+I+++E++ S + MA + FGD L P Sbjct: 61 GTAVRPMLFKDAIAVINDRAHVASEYPVIVTLENHASRETRAVMAKIMRHTFGDKLWTPP 120 Score = 105 bits (251), Expect = 1e-20 Identities = 63/222 (28%), Positives = 106/222 (47%), Gaps = 15/222 (6%) Query: 967 SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026 S+ E KA++L+ + +++ L R YP GQRI S+NY+P W+ G+ +VALN+Q Sbjct: 228 SWSENKAKKLVEKSSQKDLLEFTKAHLLRTYPGGQRIMSNNYDPSDAWSIGASLVALNFQ 287 Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL 1086 D+ M VN KF NGGCG++ KP ++ NP ++ + ++ + V + Sbjct: 288 AQDRYMWVNQAKFAVNGGCGYVKKPDYLI----NPSVQRPTKPRILRIHVFCGLGWENFK 343 Query: 1087 CKTGRGTASPFVEVEIIGADYD------SGVKLVTKTVSDNGL----NPLWNDICEFEVA 1136 F+++ + G D G + T S + P+WN+ + E+ Sbjct: 344 DADFMSAPDTFMKISLFGCVADRLSATSRGNSMRTSVYSKARVGPCAQPIWNEHFDLEIR 403 Query: 1137 NPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 PEL +++ D+D F+ + LR+G R VPL Sbjct: 404 EPELTVLQIQAMDKD-GARDEFLAHYDVAVSALREGVRIVPL 444 >UniRef50_UPI0001555F0C Cluster: PREDICTED: hypothetical protein, partial; n=2; Amniota|Rep: PREDICTED: hypothetical protein, partial - Ornithorhynchus anatinus Length = 233 Score = 103 bits (247), Expect = 3e-20 Identities = 64/194 (32%), Positives = 104/194 (53%), Gaps = 26/194 (13%) Query: 701 EIKHCRV--KQEG---RLYTIGTVKFESLIELVSYYENHPLYK---KVKLWYPISEETVR 752 +++HCR+ +Q+ + + + F+SL L+++Y+ PL +++L P+ + Sbjct: 4 KVQHCRIHSRQDAGSPKFFLTDNLVFDSLYALITHYQQVPLRCNEFEMRLTEPVPQTNAH 63 Query: 753 RLVSEPD-------------DNTVYGTPGYMDPTSFTSKVT----VKALYDYRARQDDEL 795 P T P ++ P + ++ VKAL+DY+A+++DEL Sbjct: 64 ESKDTPSVPPQKLSHCPPNAPCTSRCDPSHLVPPGLSPYLSRQCAVKALFDYKAQREDEL 123 Query: 796 SFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHTPDVTSGLENESAALGS 855 +F K AII NV+K + GWWRGDYGGK+ WFP+NYV E+ P L+ E++ LG Sbjct: 124 TFTKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMASPALEPEREQLD-ENSPLGD 182 Query: 856 LQKGVLDVLGAIVE 869 L +GVLDV +E Sbjct: 183 LLRGVLDVPSCQIE 196 Score = 87.8 bits (208), Expect = 2e-15 Identities = 39/67 (58%), Positives = 47/67 (70%) Query: 590 RQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQP 649 R GKV HCRI +Q+ G KF+L D++ FDSLY LITHY+ PLR EF + L EPVPQ Sbjct: 1 RNGKVQHCRIHSRQDAGSPKFFLTDNLVFDSLYALITHYQQVPLRCNEFEMRLTEPVPQT 60 Query: 650 NKHEGKE 656 N HE K+ Sbjct: 61 NAHESKD 67 >UniRef50_Q4QBH9 Cluster: Phosphoinositide-specific phospholipase C, putative; n=3; Leishmania|Rep: Phosphoinositide-specific phospholipase C, putative - Leishmania major Length = 555 Score = 102 bits (244), Expect = 7e-20 Identities = 53/129 (41%), Positives = 77/129 (59%) Query: 307 VTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTPF 366 V QDM + + Y+ISSSHNTYLTGDQ +S+SS + Y + E C +GP G P Sbjct: 191 VYQDMDQIMCCYFISSSHNTYLTGDQLTSKSSAQMYKKGASRRVPVREAICRNGPHGEPI 250 Query: 367 IYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDLL 426 + HG+T T+ I F + ++ I+++AF S Y +ILS+ + S+ QQ +MA ++ G LL Sbjct: 251 VCHGYTRTSCIAFEECVKMIRQYAFTASAYLVILSLGVHTSVEQQDKMAEILEEGLGSLL 310 Query: 427 LVHPMDKNE 435 P NE Sbjct: 311 FWPPWGSNE 319 Score = 75.8 bits (178), Expect = 7e-12 Identities = 37/90 (41%), Positives = 57/90 (63%), Gaps = 2/90 (2%) Query: 966 SSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNY 1025 SS+ E K + ++ + N V + T LSR++P G RIDSSNY P+ +W G QMVA+N+ Sbjct: 420 SSYSERKGKAIVREAHNAL-VCINDTCLSRVFPAGSRIDSSNYRPLLYWVSGCQMVAINW 478 Query: 1026 QTPDK-PMQVNMGKFKQNGGCGFILKPQFM 1054 Q+ D ++N F +G CG++LKP ++ Sbjct: 479 QSSDTFGWRLNGCIFLDSGCCGYLLKPDYL 508 >UniRef50_Q4SCY7 Cluster: Chromosome 14 SCAF14646, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 14 SCAF14646, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 530 Score = 101 bits (243), Expect = 9e-20 Identities = 54/120 (45%), Positives = 71/120 (59%), Gaps = 3/120 (2%) Query: 262 QASQFIRDYLRDPQRDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWIS 321 +A Q I Y RD + + + F L S +N+ ++ Q+M +PL+HY+IS Sbjct: 179 RAMQIIEKYERDAELK-KKGRMSSDGFCRYLMSDENAPVFLDRLELYQEMDQPLAHYFIS 237 Query: 322 SSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD--GPDGTPFIYHGHTLTTKIRF 379 SSHNTYLTG QF +SS+E Y + L SGCRC+ELDCWD G D P I HG + T I F Sbjct: 238 SSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELDCWDGKGEDQEPIITHGKAMCTDILF 297 Score = 44.0 bits (99), Expect = 0.025 Identities = 18/45 (40%), Positives = 29/45 (64%), Gaps = 2/45 (4%) Query: 1029 DKPMQVNMGKFKQNGGCGFILKPQFM--FEEGYNPCDKKSIEGKV 1071 D MQ+N GKF+ NG CG++LKP FM + ++P + ++G + Sbjct: 451 DLAMQLNQGKFEYNGSCGYLLKPDFMRRSDRTFDPFSEIPVDGVI 495 >UniRef50_A5E691 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 538 Score = 101 bits (241), Expect = 2e-19 Identities = 75/284 (26%), Positives = 133/284 (46%), Gaps = 21/284 (7%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQ-ENTFFVKYHTT 991 +I +S+L +Y + + F L + VYN S E +++ + + T K++ Sbjct: 248 KIIDVLSELGVYIQGIKFRNFSLP-ESKVYNHCFSLSEKATNKMLKDEVKRTSLDKHNRK 306 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQ-NGGCGFILK 1050 R+YP R+ SSN+ P+ +W G QMVA N+QT D Q+N F+ + G++LK Sbjct: 307 YFLRVYPSRFRLKSSNFIPINYWKIGVQMVATNWQTYDLGQQLNEAMFEDPHNKSGYVLK 366 Query: 1051 PQFMFEEGYNPCD-KKSIEGKVKPVTVMLRVIGARHL-CKTGRGTASPFVEVEIIGAD-- 1106 P ++ + K + + + ++GA L T +PFV VE+IGAD Sbjct: 367 PSYLRKPIIKSSKFYKMPSPPAEKIKFSITIVGAHELPTSTYADVLNPFVTVEVIGADSI 426 Query: 1107 ----YDSGVKLVTKTVSDNGLNPLWNDICEFEVAN-PELALIRFVV-------QDEDIFG 1154 + + T+ +++NG +P+W++ E+ + ++FVV + F Sbjct: 427 ESDTEEGELGKRTRVINNNGFSPIWDETFNGEITGLRDFIFVKFVVGSYSTPWSESSKFD 486 Query: 1155 --EPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLS 1196 P + L L++GY+ + L + F E L S+L V +S Sbjct: 487 THTPATVAMVVTKLDHLQQGYQHLHLKDPFGERLPFSSLFVKVS 530 Score = 92.3 bits (219), Expect = 7e-17 Identities = 64/162 (39%), Positives = 83/162 (51%), Gaps = 32/162 (19%) Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYV-------RCLR--------SGCRCIELD 356 + PL+ Y+ISSSHNTYL G Q ESSLE Y+ RC+ G + LD Sbjct: 22 SHPLTDYYISSSHNTYLIGRQVGGESSLEGYIKALKKGCRCVEIDVWDGSGGGASSLVLD 81 Query: 357 CWDGPDGT--------------PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSI 402 T P + HG T T I+F DV+RTIKE+AF +S YP+ILS+ Sbjct: 82 GNSANTNTNGGTSAATIAVVAEPVVNHGRTFTKSIKFSDVIRTIKEYAFESSPYPVILSL 141 Query: 403 EDNCSLPQQRRMASAFQDVFGDLLLVHPMDKNETS-LPSPHD 443 E NCS QR + + ++ G L+ + NE S LPSP D Sbjct: 142 EINCSANYQRSVVTIIKETLGKSLVTETI--NEYSILPSPED 181 >UniRef50_UPI0000447A3F Cluster: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148); n=2; Gallus gallus|Rep: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) - Gallus gallus Length = 174 Score = 100 bits (239), Expect = 3e-19 Identities = 56/121 (46%), Positives = 70/121 (57%), Gaps = 6/121 (4%) Query: 538 ELHFAECWFHGKLAGNR---QEAEDLLRAHA-HLGD--GTFLVRESVTFVGDYCLSFWRQ 591 ELH A+ WFH KL R AE LL + +GD G+FLVRES TFVGDY LS W Sbjct: 50 ELHLAQDWFHSKLGEGRVGWHMAEWLLTEYCTEMGDPDGSFLVRESGTFVGDYVLSLWCN 109 Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNK 651 KV HC I Q+ +++F+L D+ FDSL+N IT YR + + L E VP+ N Sbjct: 110 EKVQHCCIHWWQDASISRFFLTDNWVFDSLFNFITRYRETLPGYNKLEMRLTEAVPRSNT 169 Query: 652 H 652 H Sbjct: 170 H 170 Score = 35.9 bits (79), Expect = 6.7 Identities = 30/107 (28%), Positives = 51/107 (47%), Gaps = 16/107 (14%) Query: 652 HEGKEWFHAHCTRTQ-----AEELLRKTNT-----DGAFLVRPSEKEQGSFAISFRTEKE 701 H ++WFH+ + AE LL + T DG+FLVR S G + +S ++ Sbjct: 52 HLAQDWFHSKLGEGRVGWHMAEWLLTEYCTEMGDPDGSFLVRESGTFVGDYVLSLWCNEK 111 Query: 702 IKHCRVK--QE---GRLYTIGTVKFESLIELVS-YYENHPLYKKVKL 742 ++HC + Q+ R + F+SL ++ Y E P Y K+++ Sbjct: 112 VQHCCIHWWQDASISRFFLTDNWVFDSLFNFITRYRETLPGYNKLEM 158 >UniRef50_Q013R6 Cluster: Phosphoinositide-specific phospholipase C; n=1; Ostreococcus tauri|Rep: Phosphoinositide-specific phospholipase C - Ostreococcus tauri Length = 616 Score = 100 bits (239), Expect = 3e-19 Identities = 65/229 (28%), Positives = 109/229 (47%), Gaps = 20/229 (8%) Query: 967 SFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQ 1026 S+ E K + + ++ + +++ L R YP G RI S+NY+P W+ G+ VALN+Q Sbjct: 378 SWSERKLKLKIEKESSKDIIEFTNAHLLRTYPAGHRIFSNNYDPSEAWDVGASFVALNFQ 437 Query: 1027 TPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRV---IGA 1083 D+ + N KF+ NG CG++ KP ++ + +IE KP + ++V IG Sbjct: 438 ALDRYVWANRAKFRVNGNCGYVKKPAYLLD--------PTIERPSKPRRLQVKVFAGIGW 489 Query: 1084 RHLCKTGR-GTASPFVEVEIIGADYD-------SGVKLVTKTVSDNGLNPLWNDICEFEV 1135 + R + + +G D + + +K + P+WND E + Sbjct: 490 DNFKDADRFSPPDSLIRITTLGCLADRTKPGKSNRTSVYSKARAGPEAQPVWNDTFELAI 549 Query: 1136 ANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSE 1184 PELAL++ D+D G+ + FP+ LR+G R VP+ N E Sbjct: 550 FEPELALMQIQALDKDGNGD-ELLAHYDFPISKLREGVRIVPMLNRDDE 597 Score = 94.7 bits (225), Expect = 1e-17 Identities = 47/121 (38%), Positives = 69/121 (57%), Gaps = 4/121 (3%) Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD----GPDGTP 365 +MT +S Y+++SSHNTYL GDQ S +S+ A L GCR IELD +D G P Sbjct: 118 EMTSEMSAYFVNSSHNTYLDGDQLFSRASVAAIAGALDRGCRVIELDVYDGKKRGDKPRP 177 Query: 366 FIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGDL 425 + HG T + F D ++ I E A + SEYP+I+++E++ S + M+ + GD Sbjct: 178 IVTHGGTAVRPMYFEDAIKVIAERAHVASEYPVIVTLENHASKETRAEMSRILRSTLGDK 237 Query: 426 L 426 L Sbjct: 238 L 238 >UniRef50_A7ASE0 Cluster: Phospholipase C gamma 1, putative; n=1; Babesia bovis|Rep: Phospholipase C gamma 1, putative - Babesia bovis Length = 1027 Score = 100 bits (239), Expect = 3e-19 Identities = 56/150 (37%), Positives = 82/150 (54%), Gaps = 4/150 (2%) Query: 283 FTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEA 341 FT+ F L K N+ Q +++ + PL+ +WI+SSHNTYLTG+Q ++ A Sbjct: 493 FTIMGFHWSLAQKFNAATIPQDAEEILNLLKYPLNSFWIASSHNTYLTGNQVGGAAAAGA 552 Query: 342 YVRCLRSGCRCIELDCWDGPDGTPFIYHGH---TLTTKIRFMDVLRTIKEHAFITSEYPL 398 L GCRCIELDC DGP+G P + H LT I + L KE AF S+ P+ Sbjct: 553 LADALLRGCRCIELDCQDGPNGEPVLCHSWKNCQLTGSITLSEALIACKETAFKFSKLPV 612 Query: 399 ILSIEDNCSLPQQRRMASAFQDVFGDLLLV 428 ILS++ +C+ + + A + + GD L + Sbjct: 613 ILSMQMHCTDECKMKTAETCRKILGDALYI 642 Score = 67.3 bits (157), Expect = 2e-09 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 4/89 (4%) Query: 963 NEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVA 1022 N + S E+K ++ + Q F + + RIYP G R+ S+N+ P+ W G Q VA Sbjct: 710 NNVYSLNESKFAKVAAHQ--AFLRRLTDISMIRIYPSGTRVASTNFCPLNAWASGIQCVA 767 Query: 1023 LNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 LNYQ+ D+ M +N GKF Q+ G++LKP Sbjct: 768 LNYQSCDRSMLINYGKFNQS--FGYVLKP 794 Score = 54.8 bits (126), Expect = 1e-05 Identities = 36/106 (33%), Positives = 55/106 (51%), Gaps = 9/106 (8%) Query: 1096 PFVEVEIIGADYDSGVKLV-TKTVSDNGLNPLWNDIC---EFEVANPELALIRFVVQDED 1151 PFVE+ ++G G +++ T+ V+ NG NP+W D EF V P LA++ V+ D Sbjct: 923 PFVEIVLVG----KGERILKTEIVNFNGFNPVWADTTPPFEFIVKEPNLAVLLLAVKHHD 978 Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 G IGQ P+ +R G R L + E+E L++H+ I Sbjct: 979 NVGV-QIIGQTALPVNRIRPGIRWAQLLDQRLMEIECCGLLLHIDI 1023 >UniRef50_UPI0000E497E3 Cluster: PREDICTED: similar to protein-tyrosine phosphatase; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to protein-tyrosine phosphatase - Strongylocentrotus purpuratus Length = 533 Score = 98.7 bits (235), Expect = 8e-19 Identities = 66/196 (33%), Positives = 100/196 (51%), Gaps = 13/196 (6%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH ++G EAE LL + DG FL R S + GD+ LS R G+V H +I Q Sbjct: 6 WFHPNISG--MEAEQLLLNNGF--DGCFLCRPSKSNPGDFTLSVRRNGEVTHIKI---QN 58 Query: 605 RGVTKFYLIDSMCFDSLYNLITHY---RSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAH 661 G F L F +L L+ HY R+ +I LK P+ + + WFH H Sbjct: 59 TG-DFFDLYGGEKFATLAELVQHYTEGRNQLKERNGQMIELKYPLNCADP-TNERWFHGH 116 Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI-GTVK 720 T +AE+ L +G++LVR S + G + +S RTE ++ H ++ + Y + G + Sbjct: 117 ITGKEAEKSLVDKGKNGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQDTKYDVGGGEQ 176 Query: 721 FESLIELVSYYENHPL 736 FE+L +LV +Y +P+ Sbjct: 177 FETLTDLVDHYRKNPM 192 Score = 64.9 bits (151), Expect = 1e-08 Identities = 29/78 (37%), Positives = 44/78 (56%), Gaps = 1/78 (1%) Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714 + WFH + + +AE+LL DG FL RPS+ G F +S R E+ H +++ G + Sbjct: 4 RRWFHPNISGMEAEQLLLNNGFDGCFLCRPSKSNPGDFTLSVRRNGEVTHIKIQNTGDFF 63 Query: 715 TI-GTVKFESLIELVSYY 731 + G KF +L ELV +Y Sbjct: 64 DLYGGEKFATLAELVQHY 81 Score = 56.4 bits (130), Expect = 4e-06 Identities = 37/104 (35%), Positives = 58/104 (55%), Gaps = 9/104 (8%) Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602 E WFHG + G +EAE L +G++LVRES + GDY LS + KV H I+ + Sbjct: 110 ERWFHGHITG--KEAEKSLVDKGK--NGSYLVRESHSKPGDYVLSVRTEDKVTHVMIRCQ 165 Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEP 645 TK+ + F++L +L+ HYR +P+ + +++ LK P Sbjct: 166 D----TKYDVGGGEQFETLTDLVDHYRKNPMVETTGYVVHLKVP 205 >UniRef50_Q0UE70 Cluster: Putative uncharacterized protein; n=4; Dikarya|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 573 Score = 97.5 bits (232), Expect = 2e-18 Identities = 52/125 (41%), Positives = 69/125 (55%), Gaps = 7/125 (5%) Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDG--TPFI 367 D PL Y+ISSSHNTYL Q ES AY L +G RC+E+D WD D P + Sbjct: 100 DRNHPLPEYFISSSHNTYLMAHQLFGESHASAYEIALYTGSRCVEIDAWDNDDNKEEPKV 159 Query: 368 YHGHTLTTKIRFMDVLRTI-----KEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 HG+TL + I F V T+ KE A P+++S+E++C Q R+A ++VF Sbjct: 160 THGYTLVSNIPFRTVCETLRDVVDKEAAEERHAAPIMISLENHCDAHGQARLAQIMREVF 219 Query: 423 GDLLL 427 GD LL Sbjct: 220 GDRLL 224 Score = 70.9 bits (166), Expect = 2e-10 Identities = 59/229 (25%), Positives = 101/229 (44%), Gaps = 26/229 (11%) Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ L R++PKG RI S N PVPFW G+Q+ ALN+QT Q+N F +G G Sbjct: 352 RHNAHHLMRVFPKGTRISSKNLAPVPFWGIGAQICALNWQTFGAASQLNEALFAGSG--G 409 Query: 1047 FILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-CKTGRGT--ASPFVEVEII 1103 ++LKP + G D G+ + + L V GA + R T P++ ++ Sbjct: 410 YVLKPAALRAGG----DGNLNTGRRR--KLRLHVAGATDVPLPKDRETDDIKPYLTCTMV 463 Query: 1104 GADYDSGVKLVTKTV------------SDN--GLNPLWNDICEFEVANPELALIRFVVQD 1149 + + + KT DN +P+W ++ E+E + EL +R +++ Sbjct: 464 HPSDLNNMPVKRKTAGYKPHKLTSFLHKDNSPSTDPIWKEVLEWEYEDNELVFLRLLIKS 523 Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSII 1198 +D F A L+ G+ + + + E TL+V + Sbjct: 524 DDSFARNPIFAVAAVRLMYAAPGWSFIRMLDLGGHE-TTCTLLVRFEFV 571 >UniRef50_Q9UKW4 Cluster: Protein vav-3; n=96; Euteleostomi|Rep: Protein vav-3 - Homo sapiens (Human) Length = 847 Score = 93.9 bits (223), Expect = 2e-17 Identities = 69/196 (35%), Positives = 100/196 (51%), Gaps = 15/196 (7%) Query: 646 VPQPNKHEGKEWFHAHCTRTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKH 704 VP+P + + W+ R QAE EL+ + N+ +LVR KE G +AIS + E KH Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS--TYLVRHRTKESGEYAISIKYNNEAKH 718 Query: 705 CRV-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTV 763 ++ ++G + KF+SL+ELV YY++H L K + + T++ EP+ + Sbjct: 719 IKILTRDGFFHIAENRKFKSLMELVEYYKHHSL----KEGFRTLDTTLQFPYKEPEHSA- 773 Query: 764 YGTPGYMDPTSFTS-KVTVKAL--YDYRARQDDELSFCKHAIITNVDKPD-EGWWRGDYG 819 G G S S KV A+ YD+ AR ELS K ++ K GWWRG+ Sbjct: 774 -GQRGNRAGNSLLSPKVLGIAIARYDFCARDMRELSLLKGDVVKIYTKMSANGWWRGEVN 832 Query: 820 GKRHHWFPANYVLEIE 835 G R WFP+ YV E E Sbjct: 833 G-RVGWFPSTYVEEDE 847 Score = 40.3 bits (90), Expect = 0.31 Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 11/124 (8%) Query: 534 VPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593 VP+ + + W+ G + + E E + R ++ T+LVR G+Y +S + Sbjct: 661 VPKPVDYSCQPWYAGAMERLQAETELINRVNS-----TYLVRHRTKESGEYAISIKYNNE 715 Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEPVPQPNK 651 H IK+ G F++ ++ F SL L+ +Y+ H L+ + TL+ P +P Sbjct: 716 AKH--IKILTRDGF--FHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEH 771 Query: 652 HEGK 655 G+ Sbjct: 772 SAGQ 775 >UniRef50_A4RIZ5 Cluster: Putative uncharacterized protein; n=2; Sordariomycetes|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 636 Score = 91.9 bits (218), Expect = 1e-16 Identities = 84/265 (31%), Positives = 127/265 (47%), Gaps = 33/265 (12%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I +S + +Y R V+F + + + N + S E A ++ FF +++ Sbjct: 366 KITPRLSRMGVYTRGVSFK-SLSQAEATMPNHIFSLSEKVAFDTQRREPGAFF-EHNRNY 423 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 L R+YP G R DSSN++PV FW G+Q+VALN+Q+ D M +N G F G G+++KP Sbjct: 424 LMRLYPHGMRFDSSNFDPVIFWRAGAQVVALNWQSWDSGMMLNEGMFA--GSDGYVVKP- 480 Query: 1053 FMFEEGYNPCDKKSIEGKVKPV-TVMLRVIGARHL-CKTGRGTAS---PFVEV------- 1100 EGY D K + + + V + V+ ++L G+G AS P+V+V Sbjct: 481 ----EGYRSSDSKDRALQSRTLDKVSITVLAGQNLPLLGGKGDASSFIPYVKVGLHTEPD 536 Query: 1101 ---EIIGADYDS-GVKLV---TKTVSDNGLNP-LWNDICEF---EVANPELALIRFVVQD 1149 ++G D V+ V T+ G +P DI EF E PEL + FVV + Sbjct: 537 PLAAMVGEDATPLDVRQVGYSGTTIKSTGTSPDFGGDIIEFLNVEGVVPELTFLSFVVMN 596 Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYR 1174 D+ G A L LR GYR Sbjct: 597 -DVVGPDVVAAWACIRLDRLRAGYR 620 Score = 82.2 bits (194), Expect = 8e-14 Identities = 35/54 (64%), Positives = 44/54 (81%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362 QD++ PLS Y+ISSSHNTYLTG+Q SS+SS++AY L GCRCIE+D WDG + Sbjct: 103 QDLSLPLSDYFISSSHNTYLTGNQLSSDSSVDAYKDVLLRGCRCIEIDVWDGEE 156 Score = 74.5 bits (175), Expect = 2e-11 Identities = 36/81 (44%), Positives = 52/81 (64%), Gaps = 1/81 (1%) Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 G P + HG TLT ++ F DV R +KE+AF S+ PLI+S+E +CS QQ M ++ + Sbjct: 229 GEPRVLHGFTLTKEVLFRDVCRVVKEYAFAVSDLPLIVSLEVHCSPLQQNAMCDIMEEAW 288 Query: 423 GDLLLVHPMDKNETSLPSPHD 443 + LL P +++ TSLPSP D Sbjct: 289 EEFLLPTP-EEDPTSLPSPAD 308 >UniRef50_UPI00015A79D6 Cluster: hypothetical protein LOC550452; n=1; Danio rerio|Rep: hypothetical protein LOC550452 - Danio rerio Length = 250 Score = 91.5 bits (217), Expect = 1e-16 Identities = 66/198 (33%), Positives = 98/198 (49%), Gaps = 25/198 (12%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV-KQEGRLYT 715 WF +R AEE L GAFL+R S+ G F+IS R + +++H +V K + Y Sbjct: 58 WFKESASRGSAEETLMSREV-GAFLIRGSQSSPGDFSISVRHDYDVQHFKVMKDKSGHYY 116 Query: 716 IGTVKFESLIELVSYYENHPLYK------KVKLWYPISEETVR-------------RLVS 756 + T KF SL +LV +Y+ + K ++KL +E+ R L++ Sbjct: 117 LWTEKFTSLNKLVDFYKTTSISKQKEIFLRLKLSSLSDKESARSSASPRWWLWQSTNLIT 176 Query: 757 EPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRG 816 +P N P + P S + V+A+YD+ A +DDEL F II +D+ D WW+G Sbjct: 177 KPQHNRSNSQP-KVKPN--RSTIQVRAIYDFTAEEDDELGFNSGDIIEVLDRSDASWWKG 233 Query: 817 DYGGKRHHWFPANYVLEI 834 G R FPANY +I Sbjct: 234 RLRG-RSGLFPANYTEQI 250 >UniRef50_Q4N7P5 Cluster: Phospholipase C, putative; n=2; Theileria|Rep: Phospholipase C, putative - Theileria parva Length = 974 Score = 90.6 bits (215), Expect = 2e-16 Identities = 57/150 (38%), Positives = 77/150 (51%), Gaps = 5/150 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQ-YDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLE 340 + TL F L S N I Q D++ ++ L +WISSSHNTYL GDQ ++ Sbjct: 438 FLTLLGFNWSLTSNFNDICIPQDSDEIFSVLSLTLRDFWISSSHNTYLIGDQLGGSATAG 497 Query: 341 AYVRCLRSGCRCIELDCWDGPDGTPFIYHGHT---LTTKIRFMDVLRTIKEHAFITSEYP 397 A L GCRCIELDC DG + P + H LT + + L IKE AF +++ P Sbjct: 498 ALAEALLRGCRCIELDCQDGAE-EPVLCHAWKNCHLTGSVTLREGLIAIKESAFESNKLP 556 Query: 398 LILSIEDNCSLPQQRRMASAFQDVFGDLLL 427 +ILS E +CS + + + GD LL Sbjct: 557 VILSFEMHCSDEFKFQSFELVTQILGDELL 586 Score = 64.1 bits (149), Expect = 2e-08 Identities = 39/110 (35%), Positives = 60/110 (54%), Gaps = 7/110 (6%) Query: 1091 RGTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDI---CEFEVANPELALIRFVV 1147 R PFVEV ++G D ++ TK V+ N NP+W+D F++ NP A++ F V Sbjct: 863 RQKVCPFVEVSVVGEDENT---CKTKPVNFNTFNPVWSDSNPPFTFKIRNPNEAILLFYV 919 Query: 1148 QDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 + D +GQA FP+ LR G R V L ++ E++ S L+VH+ + Sbjct: 920 KHYDSISS-EVLGQAAFPVNRLRPGIRWVQLLDSKFMEIDCSGLLVHIEM 968 Score = 50.4 bits (115), Expect = 3e-04 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 2/93 (2%) Query: 952 IERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPV 1011 ++ +I+ N + + ETK ++ +E + R+YP R+ S+N+ PV Sbjct: 644 VDEKKIETLKRNSVFAISETKFIKI--SKEPSLLNALAERCFVRVYPSATRLASTNFCPV 701 Query: 1012 PFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGG 1044 W+ G Q ALN+Q+ D+ M +N G+F + G Sbjct: 702 KPWSHGVQFAALNFQSFDRSMLINYGRFYHSFG 734 >UniRef50_Q06124 Cluster: Tyrosine-protein phosphatase non-receptor type 11; n=73; Bilateria|Rep: Tyrosine-protein phosphatase non-receptor type 11 - Homo sapiens (Human) Length = 597 Score = 89.0 bits (211), Expect = 7e-16 Identities = 66/206 (32%), Positives = 103/206 (50%), Gaps = 23/206 (11%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH + G EAE+LL DG+FL R S + GD+ LS R G V H +I Q Sbjct: 6 WFHPNITG--VEAENLLLTRGV--DGSFLARPSKSNPGDFTLSVRRNGAVTHIKI---QN 58 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEF---LITLKEPVPQPNKHEGKEWFHAH 661 G + L F +L L+ +Y H + +E +I LK P+ + + WFH H Sbjct: 59 TG-DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADP-TSERWFHGH 116 Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT----------EKEIKHCRVKQEG 711 + +AE+LL + G+FLVR S+ G F +S RT + ++ H ++ + Sbjct: 117 LSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQE 176 Query: 712 RLYTI-GTVKFESLIELVSYYENHPL 736 Y + G +F+SL +LV +Y+ +P+ Sbjct: 177 LKYDVGGGERFDSLTDLVEHYKKNPM 202 Score = 70.5 bits (165), Expect = 3e-10 Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 7/100 (7%) Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714 + WFH + T +AE LL DG+FL RPS+ G F +S R + H +++ G Y Sbjct: 4 RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYY 63 Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747 + G KF +L ELV YY E+H K+ ++L YP++ Sbjct: 64 DLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLN 103 Score = 49.6 bits (113), Expect = 5e-04 Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 19/116 (16%) Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR----------Q 591 +E WFHG L+G +EAE LL G+FLVRES + GD+ LS + Sbjct: 109 SERWFHGHLSG--KEAEKLLTEKGK--HGSFLVRESQSHPGDFVLSVRTGDDKGESNDGK 164 Query: 592 GKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646 KV H I+ ++ K+ + FDSL +L+ HY+ +P+ + ++ LK+P+ Sbjct: 165 SKVTHVMIRCQE----LKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPL 216 >UniRef50_P29349 Cluster: Tyrosine-protein phosphatase corkscrew; n=15; Eumetazoa|Rep: Tyrosine-protein phosphatase corkscrew - Drosophila melanogaster (Fruit fly) Length = 845 Score = 88.6 bits (210), Expect = 9e-16 Identities = 62/197 (31%), Positives = 105/197 (53%), Gaps = 16/197 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH ++G EAE LL+ DG+FL R S + G + LS R +V H +I Q Sbjct: 6 WFHPTISGI--EAEKLLQEQGF--DGSFLARLSSSNPGAFTLSVRRGNEVTHIKI---QN 58 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSH-PLRSQEF-LITLKEPV--PQPNKHEGKEWFHA 660 G F L F +L L+ +Y + L+ + I LK+P+ +P + WFH Sbjct: 59 NG-DFFDLYGGEKFATLPELVQYYMENGELKEKNGQAIELKQPLICAEPTT---ERWFHG 114 Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI-GTV 719 + + +AE+L+ + +G+FLVR S+ + G F +S RT+ ++ H ++ + + Y + G Sbjct: 115 NLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDVGGGE 174 Query: 720 KFESLIELVSYYENHPL 736 F +L EL+ +Y+ +P+ Sbjct: 175 SFGTLSELIDHYKRNPM 191 Score = 64.9 bits (151), Expect = 1e-08 Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 2/87 (2%) Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714 + WFH + +AE+LL++ DG+FL R S G+F +S R E+ H +++ G + Sbjct: 4 RRWFHPTISGIEAEKLLQEQGFDGSFLARLSSSNPGAFTLSVRRGNEVTHIKIQNNGDFF 63 Query: 715 TI-GTVKFESLIELVSYY-ENHPLYKK 739 + G KF +L ELV YY EN L +K Sbjct: 64 DLYGGEKFATLPELVQYYMENGELKEK 90 Score = 53.6 bits (123), Expect = 3e-05 Identities = 34/91 (37%), Positives = 50/91 (54%), Gaps = 8/91 (8%) Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602 E WFHG L+G +EAE L+ +G+FLVRES + GD+ LS KV H I+ + Sbjct: 109 ERWFHGNLSG--KEAEKLILERGK--NGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQ 164 Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 + K+ + F +L LI HY+ +P+ Sbjct: 165 DK----KYDVGGGESFGTLSELIDHYKRNPM 191 >UniRef50_Q2H4G2 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 693 Score = 86.2 bits (204), Expect = 5e-15 Identities = 42/81 (51%), Positives = 57/81 (70%), Gaps = 3/81 (3%) Query: 282 YFTLSEFVEMLYSKQNSIYDSQYDKVTQ--DMTRPLSHYWISSSHNTYLTGDQFSSESSL 339 Y+ EF L+S+ S + + ++ Q D TRP+S+Y+ISSSHNTYL G+Q SS+SS Sbjct: 114 YYRFDEFF-WLWSQTESAWRAAGEQQQQEVDATRPISNYFISSSHNTYLEGNQLSSKSSA 172 Query: 340 EAYVRCLRSGCRCIELDCWDG 360 EAY LR+GCRCIE+D W+G Sbjct: 173 EAYRAALRNGCRCIEIDVWNG 193 Score = 62.5 bits (145), Expect = 7e-08 Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 3/125 (2%) Query: 934 IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTF-FVKYHTTQ 992 I + +S+L IY S + + + + S E E L +K++ Sbjct: 401 ICRALSELAIYTHSQHYTDDSSLDTCQAPSHIFSLSEDSFEALTEDHNKLQKMLKHNRDF 460 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 RIYPKG R+DSSN +P W G QMVA+N+Q D+ M +N F G G+ILKP Sbjct: 461 FMRIYPKGLRVDSSNPDPSFHWRRGVQMVAMNWQKSDEGMLINDAMFA--GTNGWILKPP 518 Query: 1053 FMFEE 1057 + + Sbjct: 519 ALLSD 523 Score = 45.2 bits (102), Expect = 0.011 Identities = 21/63 (33%), Positives = 35/63 (55%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P ++H T+T+ + F +V R I+E AF + P+I+S+E QQ M ++ + Sbjct: 283 PVVHHHGTMTSTVGFREVCRAIRESAFEKNPLPIIISLEVGADWEQQEVMVKIMKEEWNG 342 Query: 425 LLL 427 LLL Sbjct: 343 LLL 345 >UniRef50_Q9STZ3 Cluster: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase; n=4; Arabidopsis thaliana|Rep: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase - Arabidopsis thaliana (Mouse-ear cress) Length = 531 Score = 85.4 bits (202), Expect = 8e-15 Identities = 53/201 (26%), Positives = 94/201 (46%), Gaps = 7/201 (3%) Query: 983 TFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQN 1042 T + + + R P+ + + + Y P W G+Q++AL+ + + + + G F+ N Sbjct: 313 TDIISFTQKRFLRTRPQRKLLIYAPYKPQRAWMHGAQLIALSRKEEKEKLWLMQGMFRAN 372 Query: 1043 GGCGFILKPQFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHLC----KTGR-GTASPF 1097 GGCG++ KP F+ G + ++ V + + +G + + GR + Sbjct: 373 GGCGYVKKPDFLLNAGPSGVFYPTVNPVVVKILKVKIYMGDGWIVDFKKRIGRLSKPDLY 432 Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157 V + I G +D + + TV +N P W + F + P+LALI F V D ++ Sbjct: 433 VRISIAGVPHDENI--MKTTVKNNEWTPTWGEEFTFPLTYPDLALISFEVYDYEVSTADA 490 Query: 1158 FIGQATFPLLCLRKGYRSVPL 1178 F GQ P+ L +G R+VPL Sbjct: 491 FCGQTCLPVSELIEGIRAVPL 511 Score = 82.6 bits (195), Expect = 6e-14 Identities = 46/137 (33%), Positives = 65/137 (47%), Gaps = 2/137 (1%) Query: 305 DKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGT 364 D+V DM PLSHY+I +S N+Y TG+ F S L + L G R +ELD W G+ Sbjct: 101 DQVHHDMHAPLSHYFIHTSLNSYFTGNVFGKYSILPI-IEALEQGVRVVELDLWPDGRGS 159 Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 + ++ + L +IKEHAF YPLI++ +D Q + Q F Sbjct: 160 ICVRPSWNFEKPLKLQECLDSIKEHAFTKCTYPLIITFKDGLKPELQSKATQMIQQTFNH 219 Query: 425 LLLVHPMDKNETSLPSP 441 ++ H E PSP Sbjct: 220 MVYHHDPHSLEV-FPSP 235 >UniRef50_Q7SE08 Cluster: Putative uncharacterized protein NCU02175.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU02175.1 - Neurospora crassa Length = 598 Score = 85.0 bits (201), Expect = 1e-14 Identities = 45/95 (47%), Positives = 61/95 (64%), Gaps = 8/95 (8%) Query: 274 PQRDIYEPYFTLSEFVEMLYSKQNSIYDS--QYDKVTQDMTRPLSHYWISSSHNTYLTGD 331 P +D+Y T EF +S + +++ D D+T P+S+Y+ISSSHNTYL G+ Sbjct: 102 PVKDVY----TFEEFF-WAWSSNKAAWNAVRPLDPTEIDLTYPISNYFISSSHNTYLEGN 156 Query: 332 QFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGTP 365 Q SS+SS EAY LR+GCRCIE+D W+G P TP Sbjct: 157 QLSSKSSAEAYKAVLRNGCRCIEIDVWNGAPSRTP 191 Score = 64.5 bits (150), Expect = 2e-08 Identities = 44/119 (36%), Positives = 60/119 (50%), Gaps = 4/119 (3%) Query: 934 IAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ- 992 I + ++ L IY RS FN + + + + S E K ++SQ E + H Q Sbjct: 384 ICEMLAALAIYTRSEHFN-DVNSLASTTPSHIFSVNEDKFIDMISQDEALSKIMDHNRQY 442 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 RIYPKG R DSSN +P W G QMVA+N+Q D+ +N F G+ILKP Sbjct: 443 FMRIYPKGLRFDSSNPDPTIPWRRGVQMVAMNWQNTDEGTMLNDAMFADTN--GWILKP 499 Score = 56.8 bits (131), Expect = 3e-06 Identities = 24/79 (30%), Positives = 42/79 (53%) Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 G P ++H T+TT + F +V + ++E AF+T+ P+I+S+E QQ M ++ + Sbjct: 263 GEPIVHHHGTMTTTVPFREVCKAVREEAFVTNHLPIIVSLEVGADREQQEMMVEIMKEEW 322 Query: 423 GDLLLVHPMDKNETSLPSP 441 LLL P + + P Sbjct: 323 AGLLLEEPFENCDRLTQQP 341 >UniRef50_P62993 Cluster: Growth factor receptor-bound protein 2; n=26; Euteleostomi|Rep: Growth factor receptor-bound protein 2 - Homo sapiens (Human) Length = 217 Score = 83.4 bits (197), Expect = 3e-14 Identities = 56/179 (31%), Positives = 88/179 (49%), Gaps = 26/179 (14%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715 WF R +AEE+L K DGAFL+R SE G F++S + +++H +V ++G Y Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775 + VKF SL ELV Y+ + + + +++ +R + P P Y Sbjct: 120 LWVVKFNSLNELVDYHRSTSVSRNQQIF-------LRDIEQVPQQ------PTY------ 160 Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 V+AL+D+ ++D EL F + I +D D WW+G G+ FP NYV + Sbjct: 161 -----VQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQT-GMFPRNYVTPV 213 Score = 52.0 bits (119), Expect = 1e-04 Identities = 38/105 (36%), Positives = 59/105 (56%), Gaps = 9/105 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WF GK+ R +AE++L H DG FL+RES + GD+ LS V H ++ L+ Sbjct: 60 WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648 G K++L + F+SL L+ ++RS + R+Q+ + E VPQ Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQ 156 Score = 38.3 bits (85), Expect = 1.3 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%) Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831 A YD++A DDELSF + I+ +++ D+ W++ + GK + P NY+ Sbjct: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53 >UniRef50_Q2H674 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 1065 Score = 82.6 bits (195), Expect = 6e-14 Identities = 48/112 (42%), Positives = 65/112 (58%), Gaps = 6/112 (5%) Query: 257 GDDEVQASQFIRDYLRDPQRDI-YEPYFTLS-----EFVEMLYSKQNSIYDSQYDKVTQD 310 G D++ + + +L+D QRD E LS + L +SI + +D Sbjct: 50 GADKLWSPEKAAAFLKDTQRDTDAERALELSTGKPWDLNAFLRYMTSSITHAISPPHEED 109 Query: 311 MTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD 362 ++ PLS Y+ISSSHNTYLTG+Q SS+SS +AY L GCRCIE+D WDG D Sbjct: 110 LSWPLSSYFISSSHNTYLTGNQLSSDSSADAYKNVLLRGCRCIEVDVWDGDD 161 Score = 65.7 bits (153), Expect = 7e-09 Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 4/126 (3%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 K ++ +I + +S L IY R V+F + + + + S E + + F Sbjct: 382 KSKKPSKIIQALSKLGIYTRGVSFKSLE-QAEATMPTHIFSLSEKGVVEVHQKSAYELF- 439 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ L R YP G RI SSN +P FW G Q+VALN+Q D+ M +N G F G G Sbjct: 440 EHNRRYLMRTYPSGLRIRSSNLDPAVFWRKGIQIVALNWQNWDEGMMLNEGMFA--GTNG 497 Query: 1047 FILKPQ 1052 ++LKP+ Sbjct: 498 YVLKPE 503 Score = 61.7 bits (143), Expect = 1e-07 Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HG+TLT ++ F +V I+++AF ++ PLI S+E +CS QQ M + + +G Sbjct: 269 PRVLHGYTLTKEVSFREVCVAIRDYAFAVTDTPLIASLEVHCSAEQQETMVAIMLETWGP 328 Query: 425 LLLVHPMDKNETSLPSP 441 LL P + + LPSP Sbjct: 329 FLLPEPKE-DAAHLPSP 344 >UniRef50_UPI0000F1F414 Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 872 Score = 81.8 bits (193), Expect = 1e-13 Identities = 41/92 (44%), Positives = 59/92 (64%), Gaps = 2/92 (2%) Query: 929 ERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKY 988 +R +++ E+SDL++Y SV F K NEMSSF E+ A +L+ ++ FV++ Sbjct: 71 KRDCKLSSELSDLVVYTSSVAFKQFDPSAKK-APNEMSSFSESDALKLI-KESGKLFVRH 128 Query: 989 HTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQM 1020 ++ QLSRIYP GQR+ SSNYNP WN G Q+ Sbjct: 129 NSVQLSRIYPSGQRVQSSNYNPQDMWNAGCQI 160 Score = 67.7 bits (158), Expect = 2e-09 Identities = 33/76 (43%), Positives = 45/76 (59%) Query: 1122 GLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPLTNA 1181 G NP W+ +F++ PEL LIRF+V+D D +F+GQ T P LR GYR V L NA Sbjct: 161 GFNPRWDCTFKFQLHVPELVLIRFMVEDHDYTTRNDFLGQFTLPFPSLRTGYRHVRLLNA 220 Query: 1182 FSEELELSTLMVHLSI 1197 + S+L +H+ I Sbjct: 221 DGCSISPSSLFIHVKI 236 >UniRef50_UPI0000E49A1C Cluster: PREDICTED: similar to Growth factor receptor-bound protein 2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Growth factor receptor-bound protein 2 - Strongylocentrotus purpuratus Length = 176 Score = 81.8 bits (193), Expect = 1e-13 Identities = 60/182 (32%), Positives = 89/182 (48%), Gaps = 27/182 (14%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE-GRLYT 715 WF TR AE LL + +GAFLVR SE +G +++S + + ++H R+ Q+ + Sbjct: 14 WFFPTITRKNAELLLMQER-NGAFLVRRSESSEGLYSLSVKYNESVQHFRILQDTAGKFH 72 Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775 + VKF SL LV YY + ++ + +S ++V + P Sbjct: 73 LWIVKFPSLDALVDYYRTTSVTRENQ----VSTQSVEQWSRNPQ---------------- 112 Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 ++ALYD+ ++ EL F K IIT +DKP + WWRG G R PA YV E E Sbjct: 113 ----RLQALYDFDPEEEGELCFRKGDIITLIDKPTKDWWRGTVDG-RTGMLPAPYVKEEE 167 Query: 836 VP 837 P Sbjct: 168 EP 169 >UniRef50_A4RFY5 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 602 Score = 81.4 bits (192), Expect = 1e-13 Identities = 51/145 (35%), Positives = 71/145 (48%), Gaps = 23/145 (15%) Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPD--GTPFI 367 D + PL Y++SSSHNTYL Q S AY LR+G RC+E+D WD D P + Sbjct: 104 DRSHPLPEYFVSSSHNTYLVAHQLYGTSCATAYRTALRTGSRCVEIDAWDNGDNRSEPKV 163 Query: 368 YHGHTLTTKIRFMDVLRTIK----EHAFITSEY-----------------PLILSIEDNC 406 HG+TL + I F V TI+ E A + P++LS+E++C Sbjct: 164 THGYTLVSNIPFRLVCETIRDVVDEEAAQAQKLPVGADAAEREDERYRPAPILLSLENHC 223 Query: 407 SLPQQRRMASAFQDVFGDLLLVHPM 431 Q R+ ++VFG LL P+ Sbjct: 224 DAAGQLRLVEIMREVFGHRLLDKPV 248 Score = 62.1 bits (144), Expect = 9e-08 Identities = 32/71 (45%), Positives = 42/71 (59%), Gaps = 3/71 (4%) Query: 989 HTTQ-LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGF 1047 H Q L R+YPKG RI S N +PFW G+Q+ A+N+QT MQ+N F G G+ Sbjct: 383 HNAQHLMRVYPKGTRISSRNMKVIPFWAVGAQICAMNWQTFGANMQMNEALFA--GTDGY 440 Query: 1048 ILKPQFMFEEG 1058 +LKPQ + G Sbjct: 441 VLKPQALRSGG 451 >UniRef50_Q13588 Cluster: GRB2-related adapter protein; n=21; Bilateria|Rep: GRB2-related adapter protein - Homo sapiens (Human) Length = 217 Score = 80.6 bits (190), Expect = 2e-13 Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 24/181 (13%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715 W+ +R AEE+L K N GAFL+R SE G F++S +++H +V +E Y Sbjct: 60 WYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYF 119 Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSF 775 + KF SL ELV +Y + KK R + D+ + +PG Sbjct: 120 LWEEKFNSLNELVDFYRTTTIAKK-------------RQIFLRDEEPLLKSPG------- 159 Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 +A +D+ A+ +LSF + II +++PD WWRG G R +FP +YV + Sbjct: 160 --ACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCG-RVGFFPRSYVQPVH 216 Query: 836 V 836 + Sbjct: 217 L 217 Score = 46.0 bits (104), Expect = 0.006 Identities = 31/103 (30%), Positives = 60/103 (58%), Gaps = 9/103 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+ G+++ RQ AE++L HLG FL+RES + G++ +S +V H ++ L++ Sbjct: 60 WYSGRIS--RQLAEEILMKRNHLG--AFLIRESESSPGEFSVSVNYGDQVQHFKV-LREA 114 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPV 646 G K++L + F+SL L+ YR+ + + ++ + +EP+ Sbjct: 115 SG--KYFLWEEK-FNSLNELVDFYRTTTIAKKRQIFLRDEEPL 154 >UniRef50_Q7PV64 Cluster: ENSANGP00000020137; n=5; Coelomata|Rep: ENSANGP00000020137 - Anopheles gambiae str. PEST Length = 185 Score = 79.8 bits (188), Expect = 4e-13 Identities = 55/177 (31%), Positives = 89/177 (50%), Gaps = 30/177 (16%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714 +W++ TR AE+LL + +GAFL+R SE G F++S + ++H +V ++ + + Sbjct: 33 DWYYGRITRADAEKLLSNKH-EGAFLIRISESSPGDFSLSVKCSDGVQHFKVLRDAQGKF 91 Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTS 774 + VKF SL ELV Y+ + + + +R +V E Sbjct: 92 FLWVVKFNSLNELVDYHRTASVSRS-------QDVKLRDMVPE----------------- 127 Query: 775 FTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 ++ V+ALYD+ A++ EL F + +IT D+ DE WW G+ G R FPA YV Sbjct: 128 ---EMLVQALYDFVAQESGELDFRRGDVITVTDRSDEHWWNGEI-GNRKGLFPAIYV 180 Score = 43.2 bits (97), Expect = 0.044 Identities = 35/105 (33%), Positives = 63/105 (60%), Gaps = 12/105 (11%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++G++ R +AE LL ++ H +G FL+R S + GD+ LS V H ++ L+ Sbjct: 34 WYYGRIT--RADAEKLL-SNKH--EGAFLIRISESSPGDFSLSVKCSDGVQHFKV-LRDA 87 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQ 648 +G KF+L + F+SL L+ ++R+ + RSQ+ + L++ VP+ Sbjct: 88 QG--KFFLW-VVKFNSLNELVDYHRTASVSRSQD--VKLRDMVPE 127 >UniRef50_Q86YU7 Cluster: FLJ00417 protein; n=4; Tetrapoda|Rep: FLJ00417 protein - Homo sapiens (Human) Length = 600 Score = 79.8 bits (188), Expect = 4e-13 Identities = 44/106 (41%), Positives = 61/106 (57%), Gaps = 7/106 (6%) Query: 1092 GTASPFVEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDED 1151 G+ PFVEVEIIG D + T+ V DNG NP W + F V PE+AL+RF+V D D Sbjct: 172 GSFDPFVEVEIIGLPVDCS-REQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHD 230 Query: 1152 IFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 G +FIGQ T + GYR V + E +E +++ VH+++ Sbjct: 231 PIGR-DFIGQRTLAFSSMMPGYRHV-----YLEGMEEASIFVHVAV 270 >UniRef50_Q5IRA3 Cluster: Phosphatidyl inositol-specific phospholipase C; n=15; Sordariomycetidae|Rep: Phosphatidyl inositol-specific phospholipase C - Cryphonectria parasitica (Chesnut blight fungus) (Endothiaparasitica) Length = 736 Score = 79.8 bits (188), Expect = 4e-13 Identities = 36/77 (46%), Positives = 50/77 (64%) Query: 286 SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345 ++F+ + S S + D++ PLS Y+ISSSHNTYLTG+Q SS++S +AY Sbjct: 106 NDFLRYMTSDATSAVTPLNAQTGGDLSYPLSSYFISSSHNTYLTGNQLSSDASTDAYKNV 165 Query: 346 LRSGCRCIELDCWDGPD 362 L GCRCIE+D WDG + Sbjct: 166 LLRGCRCIEIDVWDGDE 182 Score = 73.3 bits (172), Expect = 4e-11 Identities = 50/180 (27%), Positives = 96/180 (53%), Gaps = 10/180 (5%) Query: 927 KMERTWRIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFV 986 K ++ +I +S L IY ++V+F + + + + + S E + +Q F Sbjct: 427 KKKKPSKIIHALSALGIYTKAVSFKSLH-QPEATMPSHVFSLGEKSVREVHEKQGQDLF- 484 Query: 987 KYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCG 1046 +++ L R YP G R+ SSN +P PFW G Q+ ALN+Q D+ M +N G F +G G Sbjct: 485 EHNRKYLMRAYPSGFRVGSSNLDPTPFWRKGIQIAALNWQHWDEGMMLNEGMFAGSG--G 542 Query: 1047 FILKPQ-FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL---CKTGRGTASPFVEVEI 1102 ++LKP + ++ P + ++ + + + ++V+ A++L +T + +P+V+VE+ Sbjct: 543 YVLKPPGYRHDKPNAPAETAHVQHRT--LDLEIKVLAAQNLPLPPETSVKSFNPYVKVEL 600 Score = 67.7 bits (158), Expect = 2e-09 Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 1/106 (0%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HG+TLT ++ F +V IKE+AF ++ PLI+S+E + QQ M + + Sbjct: 306 PRVLHGYTLTKEVSFREVCLAIKEYAFAVTDLPLIVSLEVHAGPEQQEIMVKIMNETWAG 365 Query: 425 LLLVHPMDKNETSLPSPHDXXXXXXXXXXXXPEGAEESSFAVRQEE 470 LLL P +K LPSP D P G E S+ A E+ Sbjct: 366 LLL-DPPEKEADVLPSPSDLRRKILVKVKYAPPGQEVSAAAASDED 410 >UniRef50_P52735 Cluster: Protein vav-2; n=28; Euteleostomi|Rep: Protein vav-2 - Homo sapiens (Human) Length = 878 Score = 79.8 bits (188), Expect = 4e-13 Identities = 65/222 (29%), Positives = 102/222 (45%), Gaps = 33/222 (14%) Query: 643 KEPVPQPNKHE----GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRT 698 + P+ +P E WF + R Q + LL K++ G +L+R E FAIS + Sbjct: 655 RPPISRPPSREIDYTAYPWFAGNMERQQTDNLL-KSHASGTYLIRERPAEAERFAISIKF 713 Query: 699 EKEIKHCR-VKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVK-----LWYPIS--EET 750 E+KH + V+++ ++ KF+SL+ELV YY+ H L + K L YP E + Sbjct: 714 NDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERS 773 Query: 751 VRRLVSEPDDNTVYGTPGYMDP---------------TSFTSKV--TVKALYDYRARQDD 793 R S + ++ P + FT +V T A Y++ AR Sbjct: 774 ASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMR 833 Query: 794 ELSFCKHAIITNVDK--PDEGWWRGDYGGKRHHWFPANYVLE 833 ELS + ++ + D+GWW+G+ G R WFP+ YV E Sbjct: 834 ELSLREGDVVRIYSRIGGDQGWWKGETNG-RIGWFPSTYVEE 874 Score = 47.6 bits (108), Expect = 0.002 Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 12/114 (10%) Query: 535 PQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593 P E+ + A WF G + RQ+ ++LL++HA GT+L+RE + +S + Sbjct: 662 PSREIDYTAYPWFAGNM--ERQQTDNLLKSHA---SGTYLIRERPAEAERFAISIKFNDE 716 Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRS--QEFLITLKEP 645 V H ++ K ++ ++ FDSL L+ +Y+ H L+ ++ TLK P Sbjct: 717 VKHIKVVEKDNW----IHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYP 766 >UniRef50_Q0UVV5 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 617 Score = 79.4 bits (187), Expect = 5e-13 Identities = 33/51 (64%), Positives = 41/51 (80%) Query: 310 DMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360 D + P+S+Y+ISSSHNTYLTG+Q SSESS +AY L GCRC+E+D WDG Sbjct: 115 DESYPISNYFISSSHNTYLTGNQLSSESSTDAYKNVLMRGCRCVEIDVWDG 165 Score = 57.6 bits (133), Expect = 2e-06 Identities = 29/58 (50%), Positives = 36/58 (62%), Gaps = 2/58 (3%) Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 R YPKG R++SSN NP FW G Q+VALN+Q D M N F G G++LKP+ Sbjct: 451 RAYPKGLRLNSSNLNPSVFWRAGVQIVALNWQRWDGGMMQNEAMFA--GTPGWVLKPE 506 Score = 52.4 bits (120), Expect = 7e-05 Identities = 27/73 (36%), Positives = 42/73 (57%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HG+TLT + F V TI+++AF TS PLI+S+E + QQ M + + Sbjct: 244 PRVLHGYTLTKDLPFRAVCATIRDYAFKTSNLPLIVSLEVHTCPEQQEIMVELMNEYWKG 303 Query: 425 LLLVHPMDKNETS 437 LL+ P+D ++ S Sbjct: 304 LLVDLPIDPSQPS 316 >UniRef50_UPI0000E478D2 Cluster: PREDICTED: similar to SH2/SH3 adaptor Grb2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SH2/SH3 adaptor Grb2 - Strongylocentrotus purpuratus Length = 241 Score = 79.0 bits (186), Expect = 7e-13 Identities = 53/188 (28%), Positives = 95/188 (50%), Gaps = 16/188 (8%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEK--EQGSFAISFRTEKEIKHCRVKQE-GRL 713 W+ +R AEE L +DGAF++R SE + G+F++S + +++H ++ + Sbjct: 62 WYVGKISRKVAEEYLMSMPSDGAFMIRDSESNPDSGNFSLSVKFRDQVQHFKILTDLAGK 121 Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPT 773 Y + VKF S+ +LV Y++++ + + ++ ++E V +D P Sbjct: 122 YFLWVVKFTSINDLVDYHKDNSVSRTQEI--VLNEPCV-----PIEDANQRPQPAMQQSR 174 Query: 774 SFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDY---GGKRHHWFPANY 830 + VKALY++ + EL+F ++ +IT +P WW G+ G R FP NY Sbjct: 175 ERLQQ--VKALYNFESDDAQELTFKQNDVITLTGRPHADWWEGEIRAPTGTRRGIFPKNY 232 Query: 831 VLEIEVPH 838 V E++ PH Sbjct: 233 VKELD-PH 239 >UniRef50_UPI000023D8AD Cluster: hypothetical protein FG06693.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG06693.1 - Gibberella zeae PH-1 Length = 633 Score = 78.6 bits (185), Expect = 1e-12 Identities = 34/57 (59%), Positives = 42/57 (73%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDGPDGTP 365 QD+T PL+ Y+ISSSHNTYLTG+Q SS+SS + Y L G RCIE+D WDG + P Sbjct: 97 QDLTYPLASYFISSSHNTYLTGNQLSSDSSTKPYTETLLRGGRCIEIDVWDGDESEP 153 Score = 72.1 bits (169), Expect = 8e-11 Identities = 79/273 (28%), Positives = 122/273 (44%), Gaps = 40/273 (14%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 ++ +E+S + +CR V+F G + S E K + +Q + F ++ Sbjct: 353 KVIQELSKMGFHCRGVSFKSLSQPEAGMP-THIFSLSEKKVIDVHEEQADALF-NHNRHF 410 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 L R YP G RI SSN +P FW G Q+VALN+Q D+ M +N G F G G++LKP Sbjct: 411 LMRTYPWGLRIGSSNLDPSVFWRKGIQVVALNWQRWDEGMMLNEGMFAGTG--GYVLKPL 468 Query: 1053 FMFEEGYNPCDKKSIEGKVKP---VTVMLRVIGARHL-----CKTGRGTASPFVEVEI-- 1102 GY P + P + + + VI A+++ K+ RG P+V+VE+ Sbjct: 469 -----GYRPNRNDEVVSNTIPRQTLHLTITVIAAQNIPLPPGDKSARG-FEPYVKVELHV 522 Query: 1103 -------------IGADYDSGVKLVTKT----VSDNGLNPLWNDICEFEVANPELALIRF 1145 G + + K T+T V D G PL + EL+ +RF Sbjct: 523 EGPDEFHGGPIPNDGHEREGEYKARTRTQKGDVVDFGSEPL--EFPPIPHVVDELSWVRF 580 Query: 1146 VVQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 ++D++I G + A + L GYR V L Sbjct: 581 TIRDDEI-GRDDMAAWACMRVDRLGHGYRFVHL 612 Score = 61.7 bits (143), Expect = 1e-07 Identities = 29/79 (36%), Positives = 48/79 (60%), Gaps = 1/79 (1%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HG+TLT +I F V I++ AF+ S+ P+I+S+E +C+ QQ M + V+ Sbjct: 230 PRVLHGYTLTKEISFRAVCEAIRDSAFVVSDLPVIVSLEVHCNAEQQLAMVRIMKQVWEG 289 Query: 425 LLLVHPMDKNETSLPSPHD 443 LL+ P + + +LPSP + Sbjct: 290 LLVAEP-ENDPENLPSPDE 307 >UniRef50_Q9VPU1 Cluster: CG3727-PB, isoform B; n=9; Endopterygota|Rep: CG3727-PB, isoform B - Drosophila melanogaster (Fruit fly) Length = 548 Score = 78.2 bits (184), Expect = 1e-12 Identities = 36/94 (38%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Query: 644 EPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIK 703 +P+ +PN GK W++ TR+Q + +L DG FL+R SE G +++S + K Sbjct: 436 QPIERPNL-AGKSWYYGAITRSQCDTVLNGHGHDGDFLIRDSETNMGDYSVSLKAPGRNK 494 Query: 704 HCRVKQEGRLYTIGTVKFESLIELVSYYENHPLY 737 H RV E +Y IG KF SL +LV +Y+ P+Y Sbjct: 495 HFRVHVEQNMYCIGQRKFHSLDQLVDHYQRAPIY 528 Score = 56.0 bits (129), Expect = 6e-06 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 9/89 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++G + R + + +L H H DG FL+R+S T +GDY +S G+ H R+ ++Q Sbjct: 448 WYYGAIT--RSQCDTVLNGHGH--DGDFLIRDSETNMGDYSVSLKAPGRNKHFRVHVEQ- 502 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 Y I F SL L+ HY+ P+ Sbjct: 503 ----NMYCIGQRKFHSLDQLVDHYQRAPI 527 Score = 55.6 bits (128), Expect = 8e-06 Identities = 27/63 (42%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Query: 771 DPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830 DP VK Y+Y+A+Q DELS K I ++K ++GWWRG G WFP+NY Sbjct: 249 DPAEAIGTAVVK--YNYQAQQPDELSLTKGTRILILEKSNDGWWRGQ-SGNSVGWFPSNY 305 Query: 831 VLE 833 E Sbjct: 306 TTE 308 >UniRef50_A6RBI2 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 660 Score = 77.0 bits (181), Expect = 3e-12 Identities = 33/57 (57%), Positives = 44/57 (77%), Gaps = 1/57 (1%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PDGT 364 QD++ P+++Y+ISSSHNTYLTG+Q SESS + Y L GCRC+E+D WDG PD + Sbjct: 82 QDLSLPMNNYFISSSHNTYLTGNQLYSESSTKVYRDVLLKGCRCLEIDVWDGEPDSS 138 Score = 66.1 bits (154), Expect = 5e-09 Identities = 28/68 (41%), Positives = 44/68 (64%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P ++HG+TLT +I F DV TI++HAF+TS+ P+I+S+E + L QQ+ M + Sbjct: 224 PLVFHGYTLTKEITFRDVCNTIRDHAFVTSDLPIIVSLEVHACLEQQKVMVDIITQAWEG 283 Query: 425 LLLVHPMD 432 +L+ P D Sbjct: 284 MLIELPAD 291 Score = 64.1 bits (149), Expect = 2e-08 Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 4/120 (3%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I +S L IY R TF+ + + + N + S E+ + F +++ Sbjct: 373 KILHSLSRLGIYTRGHTFS-KFSQQEATQPNHIFSLSESAVRDAYENERQALF-EHNREY 430 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 + R YP G R++SSN +P +W G Q+VALN+Q DK M +N G F G G++LKP+ Sbjct: 431 MMRTYPSGLRVNSSNLDPSFYWRRGIQIVALNWQNCDKGMMMNEGMFV--GYRGWVLKPE 488 >UniRef50_A2QEJ2 Cluster: Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4; n=1; Aspergillus niger|Rep: Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4 - Aspergillus niger Length = 594 Score = 77.0 bits (181), Expect = 3e-12 Identities = 49/135 (36%), Positives = 71/135 (52%), Gaps = 13/135 (9%) Query: 234 SNGTTITLREFQNFLR--DEQHDNLGDDEVQASQFIRDYLRDPQ------RDIYEPYFTL 285 SN ITL + L D+ + +L + F+ D R+P+ ++ P TL Sbjct: 6 SNAQKITLPFAPSMLNYIDKIYSSL--TSMNQPNFLTDVQREPKGQGSTTKEHPAPLATL 63 Query: 286 SEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRC 345 + F E L S + S + D++ P++ Y+IS+SHNTYLTG+Q SES AY Sbjct: 64 AAFYEYLASPEASAMRAA---TQMDLSAPITDYFISTSHNTYLTGNQLYSESKASAYTNV 120 Query: 346 LRSGCRCIELDCWDG 360 L SGCR +E+D WDG Sbjct: 121 LLSGCRSVEIDVWDG 135 Score = 72.1 bits (169), Expect = 8e-11 Identities = 81/287 (28%), Positives = 130/287 (45%), Gaps = 37/287 (12%) Query: 933 RIAKEISDLIIYCRSVTF-NIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTT 991 +I + +S L ++ + F N + K V + + S E KA R + +++ Sbjct: 318 KILQALSKLAVFTKGFHFSNFAQPEAK--VPSHVFSLSE-KAVREAHATDGDALFEHNRH 374 Query: 992 QLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKP 1051 R+YP G R+DSSN +P FW G+QMVALN+Q DK M +N G F G G++LKP Sbjct: 375 FFMRVYPNGLRVDSSNMDPTFFWRRGAQMVALNWQNFDKAMMLNAGMFA--GEQGWVLKP 432 Query: 1052 QFMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL----CKTGRGTASPFV----EVE-- 1101 GY D + + + + + + + +++ T PFV VE Sbjct: 433 -----PGYRSSDAQPGIIEPRRLDLTIEFLAGQNIPLPPGHTNENKFYPFVTCLLHVETP 487 Query: 1102 ---IIGADYD-----SGVKLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQD 1149 AD D +G K TK+V+ G+NP EF + EL +RF ++D Sbjct: 488 DDSFAAADDDTESEKTGYKHCTKSVT--GVNPDFGGQKMEFATVSGFLDELTFVRFKIKD 545 Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLS 1196 + + A L L++GYR + L ++ E L+VH++ Sbjct: 546 NE-WMHNALAAWACIRLDRLQEGYRIIHLNDSTGAPTE-GALLVHIT 590 Score = 53.6 bits (123), Expect = 3e-05 Identities = 24/77 (31%), Positives = 44/77 (57%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HGHTLT + F +V I++ AF+ S+ P+I+S+E + L QQ+ M ++ + Sbjct: 171 PRVLHGHTLTRETSFREVCYAIRDSAFVASDLPVIVSLEVHTCLEQQQTMVEIMEEAWKG 230 Query: 425 LLLVHPMDKNETSLPSP 441 +L+ + ++P P Sbjct: 231 MLVEVTPELEAGTVPPP 247 >UniRef50_Q4S516 Cluster: Chromosome 6 SCAF14737, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 6 SCAF14737, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 393 Score = 74.9 bits (176), Expect = 1e-11 Identities = 34/84 (40%), Positives = 51/84 (60%) Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713 GKEW++ TR QAE L + +G FL+R SE F+IS + + + KH +V+ + L Sbjct: 294 GKEWYYGKVTRHQAEVALNQRGVEGDFLIRDSESSPHDFSISLKAQSKNKHFKVQLKESL 353 Query: 714 YTIGTVKFESLIELVSYYENHPLY 737 Y IG KF S+ ELV +Y+ P++ Sbjct: 354 YCIGQRKFHSMEELVEHYKKAPIF 377 Score = 56.4 bits (130), Expect = 4e-06 Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833 + Y A ++DELS K + ++K +GWWRG Y G R WFP+NYV E Sbjct: 118 FSYAAEREDELSLVKGTRVVVMEKCSDGWWRGSYSG-RSGWFPSNYVTE 165 Score = 47.6 bits (108), Expect = 0.002 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 9/93 (9%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++GK+ R +AE L GD FL+R+S + D+ +S Q K H +++LK+ Sbjct: 297 WYYGKVT--RHQAEVALNQRGVEGD--FLIRDSESSPHDFSISLKAQSKNKHFKVQLKE- 351 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637 Y I F S+ L+ HY+ P+ + E Sbjct: 352 ----SLYCIGQRKFHSMEELVEHYKKAPIFTSE 380 Score = 38.3 bits (85), Expect = 1.3 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T +V V A +DY A+QD EL K+ + +D + WWR + + P+NYV Sbjct: 2 TEEVIVIAKFDYMAQQDQELDIKKNERLWLLD-DSKSWWRVRNATNKTGFVPSNYV 56 Score = 35.5 bits (78), Expect = 8.9 Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIE 835 TV+ALY + + +EL+F K ++ V+KP D WW+ + P NYV ++ Sbjct: 206 TVQALYPFSSDNAEELNFEKGEVMEVVEKPENDPEWWKCRKADGQLGLVPKNYVTVLD 263 >UniRef50_Q5B933 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 614 Score = 74.9 bits (176), Expect = 1e-11 Identities = 77/255 (30%), Positives = 116/255 (45%), Gaps = 43/255 (16%) Query: 958 KGFVYNEMSSFPETK--------AERLMSQQENTF---FVKYHTTQLSRIYPKGQRIDSS 1006 KGF + + S PE K +ER Q + + +++ R+YP G R++SS Sbjct: 348 KGFSFKQFSQ-PEAKVPGHVFSLSERAARQADEKYGKELFEHNRKYFMRVYPYGLRVNSS 406 Query: 1007 NYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKS 1066 N +P FW G+Q+VALN+Q DK M +N G F G G+ILKPQ GY + +S Sbjct: 407 NLDPTFFWRRGAQIVALNWQNSDKGMMLNQGMFA--GEQGWILKPQ-----GYRSTEPES 459 Query: 1067 IEGKVKPVTVMLRVIGARHLC--------KTGRGTASPFVEVE---------IIGADYDS 1109 + V + + V+ + L K R + +V VE + G D Sbjct: 460 APIPRRTVDLSIEVLAGQDLTLPPGDKNEKGFRPYVACYVHVETPEDAANPGLKGDDSTD 519 Query: 1110 GVKLVTK--TVSDNGLNP-LWNDICEFEV---ANPELALIRFVVQDEDIFGEPNFIGQAT 1163 K K T + G+NP + I +F EL +RF V+D++I G + A Sbjct: 520 SEKTSYKRVTKAGEGVNPDFGSQILQFPTLPGVVEELTFVRFKVKDDEI-GFDSLASWAC 578 Query: 1164 FPLLCLRKGYRSVPL 1178 L L++GYR + L Sbjct: 579 IRLTRLQEGYRVLRL 593 Score = 59.7 bits (138), Expect = 5e-07 Identities = 33/77 (42%), Positives = 45/77 (58%), Gaps = 2/77 (2%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF-G 423 P + HGHTLT F +V I++ AFI S+ P+I+S+E + SL QQ M +D F G Sbjct: 202 PKVLHGHTLTKGTTFREVCYAIRDSAFIVSDLPVIVSLEVHASLEQQETMVEIMEDAFDG 261 Query: 424 DLLLVHP-MDKNETSLP 439 L+ V P M+ ET P Sbjct: 262 MLIQVTPEMEAMETPPP 278 Score = 46.8 bits (106), Expect = 0.004 Identities = 31/83 (37%), Positives = 47/83 (56%), Gaps = 6/83 (7%) Query: 262 QASQFIRDYLRDPQ--RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRPLSHYW 319 ++S F RD RD Q +D P +L+ F + S S + D + P++ Y+ Sbjct: 49 ESSNFSRDIQRDDQDPKD-NNPLSSLAAFHAYMASPSAS---ALRPAGPPDDSAPITDYF 104 Query: 320 ISSSHNTYLTGDQFSSESSLEAY 342 ISSSHNTYLTG+Q S+++ +AY Sbjct: 105 ISSSHNTYLTGNQLYSDAAAKAY 127 >UniRef50_Q4WX21 Cluster: Phosphoinositide-specific phospholipase C, putative; n=4; Trichocomaceae|Rep: Phosphoinositide-specific phospholipase C, putative - Aspergillus fumigatus (Sartorya fumigata) Length = 652 Score = 74.5 bits (175), Expect = 2e-11 Identities = 73/276 (26%), Positives = 128/276 (46%), Gaps = 33/276 (11%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I +S L ++ + +F + + + V + S E A ++ + ++++ Sbjct: 373 KILHSLSRLAVFTKGFSFR-QFTQPEAKVPGHVFSLSENAAREAYAKDRDAL-LEHNRHF 430 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 R+YP G R++SSN +P FW CG+Q+VALN+Q DK M +N G F G++LKPQ Sbjct: 431 FMRVYPYGLRVNSSNPDPTFFWRCGAQIVALNWQNLDKGMMLNRGMFTSEP--GWVLKPQ 488 Query: 1053 FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL-------CKTG-RGTASPFVEVEI-- 1102 GY D S K + + + + ++ ++L ++G R S ++ VE Sbjct: 489 -----GYRSSDPPSTPVKRQQLDLSIEILAGQNLPLPPGDTKESGFRPYVSCYLHVECPD 543 Query: 1103 ------IGAD--YDSGVKLVTKTV-SDNGLNPLWN-DICEFEVAN---PELALIRFVVQD 1149 G D DS +++ S G NP + + +F EL +RF V+D Sbjct: 544 EENGFPPGGDNTTDSEKTSYKRSIKSATGRNPDFGAQMIQFPTLQGVIDELTFVRFKVKD 603 Query: 1150 EDIFGEPNFIGQATFPLLCLRKGYRSVPLTNAFSEE 1185 +++ G + A L L++GYR + L + E Sbjct: 604 DEL-GRDSLAAWACLKLSRLQQGYRLIHLHDCSGAE 638 Score = 74.1 bits (174), Expect = 2e-11 Identities = 27/52 (51%), Positives = 41/52 (78%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360 +D++ P++ Y++SSSHNTYLTG+Q S+++ AY L +GCRC+E+D WDG Sbjct: 94 EDLSAPITDYYVSSSHNTYLTGNQLYSDAAAAAYTNVLLNGCRCVEIDVWDG 145 Score = 56.0 bits (129), Expect = 6e-06 Identities = 25/77 (32%), Positives = 42/77 (54%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HGHTLT +F DV I++ AF+ S+ P+I+S+E + + QQ M ++ F Sbjct: 244 PRVLHGHTLTKGTKFRDVCYAIRDSAFVASDLPVIVSLEVHTCIEQQATMVEIMEEAFKG 303 Query: 425 LLLVHPMDKNETSLPSP 441 +L+ + + P P Sbjct: 304 MLIEVTPELEASQAPPP 320 >UniRef50_Q1E522 Cluster: Putative uncharacterized protein; n=1; Coccidioides immitis|Rep: Putative uncharacterized protein - Coccidioides immitis Length = 654 Score = 74.5 bits (175), Expect = 2e-11 Identities = 39/106 (36%), Positives = 60/106 (56%), Gaps = 9/106 (8%) Query: 260 EVQASQFIRDYLRDPQRDIYEP-----YFTLSEFVEMLYSKQNSIYDSQYDKVTQDMTRP 314 E + F+R +D D+ P TL F+E + + ++ D D++ P Sbjct: 49 EESSDHFLRVVQQDDSSDLQSPAKAPVLTTLDSFMEYMSTATAMPPGARED----DLSLP 104 Query: 315 LSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG 360 +++Y+I+SSHNTYLTG+Q SE+S + Y L GCRC+E+D WDG Sbjct: 105 MTNYFINSSHNTYLTGNQLYSEASTDVYKDVLLKGCRCLEIDVWDG 150 Score = 62.9 bits (146), Expect = 5e-08 Identities = 39/120 (32%), Positives = 61/120 (50%), Gaps = 4/120 (3%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I +S L IY R TFN + + + S E + Q F ++ Sbjct: 369 KILHALSRLGIYTRGYTFN-GFSQPEATKPTHIFSLSEATLKDAHENQRKALF-DHNKNF 426 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 + R+YP G R++SSN +P W G+Q+ ALN+Q DK M +N G F ++ G++LKP+ Sbjct: 427 MMRVYPSGMRVNSSNLDPSFSWRQGAQIAALNWQNCDKGMMLNKGMFARSK--GWVLKPE 484 Score = 53.6 bits (123), Expect = 3e-05 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 7/108 (6%) Query: 365 PFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVFGD 424 P + HG+TLT ++ F DV I++ AF+TS+ P+I+S+E + S QQ M + + Sbjct: 226 PRVLHGYTLTKEVTFRDVCYAIRDTAFVTSDLPVIVSLEVHASHEQQETMVEIMMEAWKG 285 Query: 425 LL------LVHPMDKNE-TSLPSPHDXXXXXXXXXXXXPEGAEESSFA 465 +L L ++K++ LPSP P+ E+ A Sbjct: 286 MLVDFTPELAAELEKSDYKHLPSPDSLRNKILIKVKWAPDHGPETDVA 333 >UniRef50_Q0CXA3 Cluster: Putative uncharacterized protein; n=1; Aspergillus terreus NIH2624|Rep: Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624) Length = 564 Score = 74.5 bits (175), Expect = 2e-11 Identities = 31/52 (59%), Positives = 40/52 (76%), Gaps = 1/52 (1%) Query: 312 TRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWDG-PD 362 + P++ Y+ISSSHNTYLTG+Q SS+S AY L +GCRC+E+D WDG PD Sbjct: 89 SHPMTDYFISSSHNTYLTGNQLSSDSDARAYAAVLLNGCRCVEIDVWDGEPD 140 Score = 66.5 bits (155), Expect = 4e-09 Identities = 69/254 (27%), Positives = 109/254 (42%), Gaps = 36/254 (14%) Query: 948 VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQLSRIYPKGQRIDSSN 1007 + NI ++ G V+ S E KA R ++ +++ RIYP G R+ SSN Sbjct: 303 IKVNITEAKVPGHVF----SLSE-KAARAAHAKDPEALFEHNRNHFMRIYPFGLRVTSSN 357 Query: 1008 YNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQFMFEEGYNPCDKKSI 1067 +P FW G+Q+VALN+Q DK + +N F G++LKP GY D Sbjct: 358 LDPSFFWRRGAQIVALNWQNVDKGVMLNRAMFADQR--GWVLKP-----PGYRSSDGAGS 410 Query: 1068 EGKVKPVTVMLRVIGARHL----CKTGRGTASPFVEVEI-IGADYDSGV----------- 1111 K + + + VI +++ T P+V + + + D+ V Sbjct: 411 AIVRKQLDLSIEVIAGQNIPLPPGDTNEKGFHPYVACHLHVETEGDNAVGVPQGDDSTDS 470 Query: 1112 ---KLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQDEDIFGEPNFIGQATF 1164 T S G NP + + +F + EL IRF V+D++ FG + A Sbjct: 471 EKSSYKRTTKSATGCNPDFGSQLIQFPTVSGIVDELTFIRFKVKDDE-FGRDSMAAWACI 529 Query: 1165 PLLCLRKGYRSVPL 1178 L L++GYR + L Sbjct: 530 KLNHLQEGYRLIHL 543 Score = 62.5 bits (145), Expect = 7e-08 Identities = 31/84 (36%), Positives = 49/84 (58%), Gaps = 1/84 (1%) Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420 P P + HGHTLT F DV I+++AF+T++ P+I+S+E + L QQ+ M ++ Sbjct: 213 PRPEPRVLHGHTLTKGTTFRDVCYAIRDNAFVTNDMPVIVSLEVHACLEQQQTMVEIMEE 272 Query: 421 VF-GDLLLVHPMDKNETSLPSPHD 443 F G L+ V P + +P+P D Sbjct: 273 AFKGMLIEVTPEIEATKIIPAPED 296 >UniRef50_UPI000058445F Cluster: PREDICTED: similar to SH2/SH3 adaptor protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to SH2/SH3 adaptor protein - Strongylocentrotus purpuratus Length = 389 Score = 73.7 bits (173), Expect = 3e-11 Identities = 31/83 (37%), Positives = 50/83 (60%) Query: 655 KEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714 ++WFH TR +E++L G FL+R SE G FA+S + + +KH +V + + + Sbjct: 289 RDWFHGRITRQDSEKILGCPGESGLFLIRESETMPGDFAVSVKAPERVKHFKVTRSDKKF 348 Query: 715 TIGTVKFESLIELVSYYENHPLY 737 IG KFESL +LV +Y+ P++ Sbjct: 349 CIGQRKFESLDDLVDHYKRSPIF 371 Score = 56.4 bits (130), Expect = 4e-06 Identities = 31/89 (34%), Positives = 48/89 (53%), Gaps = 7/89 (7%) Query: 745 PISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIIT 804 P++ R P +T PG P S ++V +Y Y+A Q+DEL+ K + Sbjct: 81 PVTRPISPRNSESPHPHTAQ--PGNEMPFSQPARV----MYHYKAAQEDELNLNKGEQVN 134 Query: 805 NVDKPDEGWWRGDYGGKRHHWFPANYVLE 833 ++K +GWWRG+ G++ WFP+NYV E Sbjct: 135 VLEKSGDGWWRGECNGEK-GWFPSNYVSE 162 Score = 54.0 bits (124), Expect = 2e-05 Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 10/108 (9%) Query: 531 NAIVPQDELHFAEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW 589 N+ P + F + WFHG++ RQ++E +L G FL+RES T GD+ +S Sbjct: 276 NSFTPSSSVGFYDRDWFHGRIT--RQDSEKILGCPGE--SGLFLIRESETMPGDFAVSVK 331 Query: 590 RQGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637 +V H ++ ++ + I F+SL +L+ HY+ P+ S + Sbjct: 332 APERVKHFKVTRSDKK-----FCIGQRKFESLDDLVDHYKRSPIFSSD 374 Score = 37.5 bits (83), Expect = 2.2 Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%) Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 V V A +DY ++QD+ELS ++ + +D WW+ + R + P+NYV Sbjct: 7 VLVVAKWDYDSKQDEELSIKRNEKLKLID-DSRSWWKVEKQNGRCGYVPSNYV 58 Score = 35.9 bits (79), Expect = 6.7 Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 8/100 (8%) Query: 741 KLWYP---ISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSF 797 K W+P +SE+ S + G + P F VT LY ++ R D+EL+F Sbjct: 152 KGWFPSNYVSEDDTSMPNSHGSSTSSKGDDNSI-PDDFVLGVTT--LYAFKGRTDEELNF 208 Query: 798 CKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYVLEIE 835 ++ + P D+ WW+ P+NYV +E Sbjct: 209 DASELLDIISNPSDDQDWWKARNKLGTVGLVPSNYVKVVE 248 >UniRef50_Q6PE32 Cluster: Zgc:65942; n=2; Danio rerio|Rep: Zgc:65942 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 249 Score = 73.7 bits (173), Expect = 3e-11 Identities = 56/191 (29%), Positives = 96/191 (50%), Gaps = 20/191 (10%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV--KQEGRLY 714 W+ + +R A++ L GAF++R S+ G F+IS R E +++H +V ++GR Y Sbjct: 58 WYKENTSRQSAQDELM-CQPIGAFIIRGSQSSPGDFSISVRHENDVQHFKVMRDRQGRYY 116 Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW----YPISEETVRRLVSEP----DDNTVYGT 766 + + F SL +LV YY ++ + K+ +++ S + + R +E + Y + Sbjct: 117 -LWSEMFTSLNKLVDYYTHNSISKQSRVFLLTDQRSSSDFLHRKPTEAPPFRQERQDYRS 175 Query: 767 --PGYMDPTS-----FTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819 P P+ S + V+A+YD+ A DEL+F +I +D+ D WW+G Sbjct: 176 LAPPVARPSQPSLPPQVSALHVRAMYDFTAEDADELNFQAGDVIEVLDQSDRSWWKGVLR 235 Query: 820 GKRHHWFPANY 830 G R FP NY Sbjct: 236 G-RTGLFPVNY 245 Score = 37.5 bits (83), Expect = 2.2 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 9/91 (9%) Query: 553 NRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYL 612 +RQ A+D L G F++R S + GD+ +S + V H ++ ++ +G ++YL Sbjct: 64 SRQSAQDELMCQPI---GAFIIRGSQSSPGDFSISVRHENDVQHFKV-MRDRQG--RYYL 117 Query: 613 IDSMCFDSLYNLITHYRSHPL--RSQEFLIT 641 M F SL L+ +Y + + +S+ FL+T Sbjct: 118 WSEM-FTSLNKLVDYYTHNSISKQSRVFLLT 147 >UniRef50_UPI0000DB7494 Cluster: PREDICTED: similar to CG10083-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG10083-PA - Apis mellifera Length = 472 Score = 73.3 bits (172), Expect = 4e-11 Identities = 49/165 (29%), Positives = 79/165 (47%), Gaps = 7/165 (4%) Query: 680 FLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKK 739 ++ + S E AI +K++ H +V++E ++ T ++++ VS + P + Sbjct: 310 YIPKNSHVEAAKKAIEESQQKDVSHIKVQEETKIIKNKTHNVDNIVTTVSNTSSSPNQVQ 369 Query: 740 VKLWYPISEETVRRLVSEP-DDNTVY----GTPGYMDPTSFTSKVTVKALYDYRARQDDE 794 I E + E +N +Y G Y DP + K +ALYDY+A D E Sbjct: 370 ESKLSEIEESQQSSMTKEVVTENELYSQMDGQYLYFDPNNEGMKA--RALYDYQAADDTE 427 Query: 795 LSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVPHT 839 ++F IIT++D DEGWW+G + FPANYV I+ T Sbjct: 428 ITFDPGDIITHIDAIDEGWWQGLGPDGTYGLFPANYVEVIDYSTT 472 >UniRef50_UPI0000E80974 Cluster: PREDICTED: hypothetical protein; n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein - Gallus gallus Length = 184 Score = 72.1 bits (169), Expect = 8e-11 Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 1/100 (1%) Query: 1098 VEVEIIGADYDSGVKLVTKTVSDNGLNPLWNDICEFEVANPELALIRFVVQDEDIFGEPN 1157 V VEI G D + TK + +NG NP W++ +F++ P+LAL+RFVV+D D + Sbjct: 77 VRVEIHGVPADQAHQ-ETKYIENNGFNPHWDETLQFQLHVPQLALVRFVVEDYDKTSRND 135 Query: 1158 FIGQATFPLLCLRKGYRSVPLTNAFSEELELSTLMVHLSI 1197 F+GQ T ++ GYR + L + + S+L VH+ I Sbjct: 136 FVGQFTLAFANIKPGYRHIHLLSKDGTGIPPSSLFVHIRI 175 >UniRef50_UPI0000E49CFC Cluster: PREDICTED: similar to Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP); n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Ras GTPase-activating protein 1 (GTPase-activating protein) (GAP) (Ras p21 protein activator) (p120GAP) (RasGAP) - Strongylocentrotus purpuratus Length = 628 Score = 71.7 bits (168), Expect = 1e-10 Identities = 36/122 (29%), Positives = 67/122 (54%), Gaps = 1/122 (0%) Query: 642 LKEPVP-QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK 700 L +PV + + +EGK WFH + ++ +A E L K G FL+R S+K G +++SFR Sbjct: 221 LVKPVEGEIDPNEGKVWFHGNVSKEEAAETLWKDGDIGGFLIRNSDKNPGDYSLSFRGPN 280 Query: 701 EIKHCRVKQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDD 760 I+ R++++ R Y +G + SL +V +Y+ + KL P + + + + +D Sbjct: 281 TIQRFRIQKQQRQYVMGGRYYNSLDAIVDHYKKEEIIDGFKLRDPTAPKKFKNQTTSTED 340 Query: 761 NT 762 ++ Sbjct: 341 SS 342 Score = 60.9 bits (141), Expect = 2e-07 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 1/91 (1%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715 EW+H R AE L + G++LVR SE++ GS+ +S+ ++ I H RV + Sbjct: 67 EWYHGCLDRQSAELRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRVTAVCGDFY 126 Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYP 745 +G +F++L EL+ YY + + K +L YP Sbjct: 127 VGGRQFQTLPELIGYYTHISNILKNERLQYP 157 Score = 44.8 bits (101), Expect = 0.014 Identities = 38/114 (33%), Positives = 57/114 (50%), Gaps = 15/114 (13%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG L +RQ AE LR +A G++LVRES G Y LS+ Q +NH R+ Sbjct: 68 WYHGCL--DRQSAE--LRLNAADKPGSYLVRESERKPGSYVLSYLGQRGINHFRV----- 118 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKE 656 V + + F +L LI +Y S+ L+++ L+ P P P + K+ Sbjct: 119 TAVCGDFYVGGRQFQTLPELIGYYTHISNILKNER----LQYPAPPPEPVDDKK 168 Score = 42.7 bits (96), Expect = 0.058 Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 13/132 (9%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG ++ ++EA + L +G FL+R S GDY LSF + RI+ KQ+ Sbjct: 237 WFHGNVS--KEEAAETLWKDGDIGG--FLIRNSDKNPGDYSLSFRGPNTIQRFRIQ-KQQ 291 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHAHCTR 664 R Y++ ++SL ++ HY+ + L++P P K + + + Sbjct: 292 RQ----YVMGGRYYNSLDAIVDHYKKEEIIDG---FKLRDPT-APKKFKNQTTSTEDSSP 343 Query: 665 TQAEELLRKTNT 676 EEL R+ ++ Sbjct: 344 MNYEELRRRRSS 355 >UniRef50_P29350 Cluster: Tyrosine-protein phosphatase non-receptor type 6; n=39; Chordata|Rep: Tyrosine-protein phosphatase non-receptor type 6 - Homo sapiens (Human) Length = 595 Score = 71.7 bits (168), Expect = 1e-10 Identities = 64/202 (31%), Positives = 98/202 (48%), Gaps = 24/202 (11%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH L+G +AE LL+ G+FL R S GD+ LS +V H RI Q Sbjct: 4 WFHRDLSG--LDAETLLKGRGV--HGSFLARPSRKNQGDFSLSVRVGDQVTHIRI---QN 56 Query: 605 RGVTKFY-LIDSMCFDSLYNLITHYRSHP--LRSQE-FLITLKEPVPQPNKHEGKEWFHA 660 G FY L F +L L+ +Y L+ ++ +I LK P+ + + W+H Sbjct: 57 SG--DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL-NCSDPTSERWYHG 113 Query: 661 HCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEK---------EIKHCRVKQEG 711 H + QAE LL+ FLVR S + G F +S +++ + H +V EG Sbjct: 114 HMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEG 173 Query: 712 RLYTIGTVK-FESLIELVSYYE 732 YT+G ++ F+SL +LV +++ Sbjct: 174 GRYTVGGLETFDSLTDLVEHFK 195 Score = 39.9 bits (89), Expect = 0.41 Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 13/95 (13%) Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFW----RQGKVNHC 597 +E W+HG ++G +AE LL+A TFLVRES++ GD+ LS + G + Sbjct: 107 SERWYHGHMSGG--QAETLLQAKGE--PWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPL 162 Query: 598 R---IKLKQERGVTKFYLIDSMCFDSLYNLITHYR 629 R IK+ E G ++ + FDSL +L+ H++ Sbjct: 163 RVTHIKVMCEGG--RYTVGGLETFDSLTDLVEHFK 195 >UniRef50_UPI000023E2BC Cluster: hypothetical protein FG08790.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG08790.1 - Gibberella zeae PH-1 Length = 750 Score = 70.1 bits (164), Expect = 3e-10 Identities = 31/54 (57%), Positives = 42/54 (77%), Gaps = 2/54 (3%) Query: 309 QDMTRPLSHYWISSSHNTYLTGDQFSS--ESSLEAYVRCLRSGCRCIELDCWDG 360 +D+++PL++Y+ISSSHNTYL G+Q +S SS EAY L GCRCIE+D W+G Sbjct: 162 KDLSKPLTNYFISSSHNTYLVGNQLASWNRSSPEAYKTVLLRGCRCIEIDVWNG 215 Score = 65.7 bits (153), Expect = 7e-09 Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 5/154 (3%) Query: 933 RIAKEISDLIIYCRSVTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYHTTQ 992 +I + + L IY RS + + + + + S E + L +Q FV ++ Sbjct: 464 KICENLGKLAIYTRSQHYKCLATK-EAKIPAHIFSISENRILELNQKQHREMFV-HNKGY 521 Query: 993 LSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ 1052 R +P G+R DSSN +P FW G QMVA+N+Q D+ M +N G F G++LKP+ Sbjct: 522 FMRAFPAGRRFDSSNPDPSLFWRGGVQMVAMNWQYLDEGMMLNEGMFADEK--GWVLKPE 579 Query: 1053 FMFEEGYNPCDKKSIEGKVKPVTVMLRVIGARHL 1086 ++ + +S + + + + V+ +H+ Sbjct: 580 -GYQSSNTSTETQSDAAPGRTMNLRITVLAGQHI 612 Score = 52.8 bits (121), Expect = 5e-05 Identities = 24/72 (33%), Positives = 39/72 (54%) Query: 361 PDGTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQD 420 P P + HG TLT F +V R + E AF+ ++ P+I+S+E + QQ M + Sbjct: 310 PKDEPIVTHGWTLTAPCGFREVCRAVGEAAFVDNDLPIIVSLEVHADEDQQEVMVKIMKQ 369 Query: 421 VFGDLLLVHPMD 432 +G +L+ P+D Sbjct: 370 EWGQMLVDKPLD 381 >UniRef50_A7EE08 Cluster: Putative uncharacterized protein; n=1; Sclerotinia sclerotiorum 1980|Rep: Putative uncharacterized protein - Sclerotinia sclerotiorum 1980 Length = 686 Score = 70.1 bits (164), Expect = 3e-10 Identities = 40/121 (33%), Positives = 63/121 (52%), Gaps = 5/121 (4%) Query: 243 EFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQRD---IYEPYFTLSEFVEMLYSKQNSI 299 E Q +LR + G + + +L D Q + + + +F+E +Y + Sbjct: 65 EIQEYLRKLFDELRGPEPCLGREKFEKWLADVQGHTITLEKDTYKFEQFLESVYYSHSLE 124 Query: 300 YDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAYVRCLRSGCRCIELDCWD 359 + ++ D +RP+++Y+ISSSHNTYL G+Q S SS EAY L CRCIE+D + Sbjct: 125 VMKRIPEL--DQSRPITNYYISSSHNTYLEGNQLLSRSSTEAYKTALTQNCRCIEIDVHN 182 Query: 360 G 360 G Sbjct: 183 G 183 Score = 59.7 bits (138), Expect = 5e-07 Identities = 33/74 (44%), Positives = 43/74 (58%), Gaps = 4/74 (5%) Query: 978 SQQENTFFVKYHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMG 1037 S +E F ++ R +P G+R DSSN +P W G QMVALN+QT D+ M +N G Sbjct: 481 SNREQMF--AHNRNYFMRAFPAGKRFDSSNLDPSVCWRKGIQMVALNWQTLDEGMMLNEG 538 Query: 1038 KFKQNGGCGFILKP 1051 F G G+ILKP Sbjct: 539 MFA--GSQGWILKP 550 Score = 54.8 bits (126), Expect = 1e-05 Identities = 27/70 (38%), Positives = 39/70 (55%) Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 G P + HG TLT + F V + I+E AF TS P+I+S+E + QQ M ++ + Sbjct: 276 GEPLVLHGWTLTAPVGFRAVCKAIRETAFTTSPLPIIVSLEVHADHEQQEIMVDIMKEEW 335 Query: 423 GDLLLVHPMD 432 DLLL P + Sbjct: 336 EDLLLDSPFE 345 >UniRef50_UPI0000D57984 Cluster: PREDICTED: similar to CG3637-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3637-PA - Tribolium castaneum Length = 205 Score = 68.9 bits (161), Expect = 8e-10 Identities = 53/157 (33%), Positives = 79/157 (50%), Gaps = 15/157 (9%) Query: 679 AFLVRPSEKEQGSFAISF-RTEKEIKHCRVKQEGR---LYTIGTVKFESLIELVSYYENH 734 AFL + S+ E S + ++ E K + QE R G + L + S ENH Sbjct: 56 AFLTQTSQAETPSGEVRVPKSLDESKKAFLAQETREEVRVVPGQLDQSKLAQFSS--ENH 113 Query: 735 PLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDE 794 + ++ + Y E ++ +E + Y T +D + ++ ALYDY+A DDE Sbjct: 114 EVNEEQEEIY---ENVTSQVTNEQQEEVYYTTDEIVD-----TGISAVALYDYQAAADDE 165 Query: 795 LSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +SF IIT+++K DEGWWRG GK + FPANYV Sbjct: 166 ISFDPDDIITHIEKIDEGWWRGLCKGK-YGLFPANYV 201 >UniRef50_Q966Z0 Cluster: Cortactin; n=1; Suberites domuncula|Rep: Cortactin - Suberites domuncula (Sponge) Length = 477 Score = 68.5 bits (160), Expect = 1e-09 Identities = 31/61 (50%), Positives = 41/61 (67%), Gaps = 1/61 (1%) Query: 771 DPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830 +PT S + KA+YDY+A +DE+SF II N+++ DEGWW GD+ G R FPANY Sbjct: 415 EPTVVESGLRAKAVYDYQATGEDEISFDPDDIIENIEQVDEGWWIGDFNGNR-GLFPANY 473 Query: 831 V 831 V Sbjct: 474 V 474 >UniRef50_O43639 Cluster: Cytoplasmic protein NCK2; n=54; Euteleostomi|Rep: Cytoplasmic protein NCK2 - Homo sapiens (Human) Length = 380 Score = 68.5 bits (160), Expect = 1e-09 Identities = 29/84 (34%), Positives = 50/84 (59%) Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRL 713 G+EW++ + TR QAE L + +G FL+R SE F++S + + KH +V+ + Sbjct: 282 GREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNV 341 Query: 714 YTIGTVKFESLIELVSYYENHPLY 737 Y IG +F ++ ELV +Y+ P++ Sbjct: 342 YCIGQRRFHTMDELVEHYKKAPIF 365 Score = 56.8 bits (131), Expect = 3e-06 Identities = 24/49 (48%), Positives = 34/49 (69%), Gaps = 1/49 (2%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLE 833 + Y A ++DELS K + +T ++K +GWWRG Y G + WFP+NYVLE Sbjct: 120 FAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNG-QIGWFPSNYVLE 167 Score = 42.7 bits (96), Expect = 0.058 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 9/93 (9%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++G + R +AE L GD FL+R+S + D+ +S GK H +++L Sbjct: 285 WYYGNVT--RHQAECALNERGVEGD--FLIRDSESSPSDFSVSLKASGKNKHFKVQL--- 337 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637 V Y I F ++ L+ HY+ P+ + E Sbjct: 338 --VDNVYCIGQRRFHTMDELVEHYKKAPIFTSE 368 Score = 39.5 bits (88), Expect = 0.54 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T +V V A +DY A+QD EL K+ + +D + WWR R + P+NYV Sbjct: 2 TEEVIVIAKWDYTAQQDQELDIKKNERLWLLD-DSKTWWRVRNAANRTGYVPSNYV 56 >UniRef50_Q8BZ27 Cluster: Adult female vagina cDNA, RIKEN full-length enriched library, clone:9930020J04 product:similar to epidermal growth factor-receptor- binding protein GRB-4; n=5; Eutheria|Rep: Adult female vagina cDNA, RIKEN full-length enriched library, clone:9930020J04 product:similar to epidermal growth factor-receptor- binding protein GRB-4 - Mus musculus (Mouse) Length = 123 Score = 68.1 bits (159), Expect = 1e-09 Identities = 30/87 (34%), Positives = 50/87 (57%) Query: 651 KHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE 710 K G W++ TR QAE L + +G FL+R SE F++S + + + KH +V+ + Sbjct: 22 KFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQGKNKHFKVQLK 81 Query: 711 GRLYTIGTVKFESLIELVSYYENHPLY 737 +Y IG KF ++ ELV +Y+ P++ Sbjct: 82 ETVYCIGQRKFSTMEELVEHYKKAPIF 108 Score = 53.2 bits (122), Expect = 4e-05 Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 9/93 (9%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++GK+ R +AE L H GD FL+R+S + D+ +S QGK H +++LK+ Sbjct: 28 WYYGKVT--RHQAEMALNERGHEGD--FLIRDSESSPNDFSVSLKAQGKNKHFKVQLKE- 82 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE 637 Y I F ++ L+ HY+ P+ + E Sbjct: 83 ----TVYCIGQRKFSTMEELVEHYKKAPIFTSE 111 >UniRef50_P20936 Cluster: Ras GTPase-activating protein 1; n=50; Euteleostomi|Rep: Ras GTPase-activating protein 1 - Homo sapiens (Human) Length = 1047 Score = 67.7 bits (158), Expect = 2e-09 Identities = 35/94 (37%), Positives = 54/94 (57%), Gaps = 2/94 (2%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE-IKHCRVKQEGRLY 714 +W+H RT AEE LR+ G++L+R S++ GSF +SF ++ + H R+ Y Sbjct: 180 QWYHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFLSQMNVVNHFRIIAMCGDY 239 Query: 715 TIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747 IG +F SL +L+ YY + L K KL YP++ Sbjct: 240 YIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVA 273 Score = 59.3 bits (137), Expect = 6e-07 Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707 + + HEGK WFH ++ +A LL +FLVRPS+ G +++ FRT + I+ ++ Sbjct: 342 EEDPHEGKIWFHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKI 401 Query: 708 -KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP-DDNTVYG 765 + +G + S+ +++ +Y + + L P+ + +++++ D +Y Sbjct: 402 CPTPNNQFMMGGRYYNSIGDIIDHYRKEQIVEGYYLKEPVPMQDQEQVLNDTVDGKEIYN 461 Query: 766 T 766 T Sbjct: 462 T 462 Score = 46.8 bits (106), Expect = 0.004 Identities = 33/118 (27%), Positives = 58/118 (49%), Gaps = 11/118 (9%) Query: 536 QDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVN 595 +++ H + WFHGK+ ++QEA +LL + +FLVR S GDY L F + Sbjct: 342 EEDPHEGKIWFHGKI--SKQEAYNLLMTVGQV--CSFLVRPSDNTPGDYSLYFRTNENIQ 397 Query: 596 HCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHE 653 +I +++ ++S+ ++I HYR + + LKEPVP ++ + Sbjct: 398 RFKICPTPNNQ----FMMGGRYYNSIGDIIDHYRKEQIVEGYY---LKEPVPMQDQEQ 448 Score = 43.2 bits (97), Expect = 0.044 Identities = 38/106 (35%), Positives = 52/106 (49%), Gaps = 12/106 (11%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603 W+HGKL +R AE+ LR G++L+RES G + LSF Q VNH RI Sbjct: 181 WYHGKL--DRTIAEERLRQAGK--SGSYLIRESDRRPGSFVLSFLSQMNVVNHFRI---- 232 Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVP 647 + Y I F SL +LI +Y S L+ ++ L + P P Sbjct: 233 -IAMCGDYYIGGRRFSSLSDLIGYYSHVSCLLKGEKLLYPVAPPEP 277 >UniRef50_UPI0000F1F9FC Cluster: PREDICTED: similar to phospholipase C, beta 4,, partial; n=1; Danio rerio|Rep: PREDICTED: similar to phospholipase C, beta 4,, partial - Danio rerio Length = 348 Score = 67.3 bits (157), Expect = 2e-09 Identities = 28/41 (68%), Positives = 33/41 (80%) Query: 988 YHTTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTP 1028 Y+ Q+SRIYPKG R+DSSNY P FWN G QMV+LN+QTP Sbjct: 66 YNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTP 106 Score = 58.0 bits (134), Expect = 1e-06 Identities = 29/56 (51%), Positives = 39/56 (69%), Gaps = 2/56 (3%) Query: 288 FVEMLYSKQNS-IYDSQYDKVTQDMTRPLSHYWISSSHNTYLTGDQFSSESSLEAY 342 F L S +N+ ++ + D + Q+M PLSHY+ISSSHNTYLTG QF +SS+E Y Sbjct: 6 FCRYLMSDENAPVFLDRLD-LCQEMEHPLSHYFISSSHNTYLTGRQFGGKSSVEMY 60 >UniRef50_O08526 Cluster: Vav-T; n=6; Euteleostomi|Rep: Vav-T - Mus musculus (Mouse) Length = 166 Score = 67.3 bits (157), Expect = 2e-09 Identities = 50/146 (34%), Positives = 72/146 (49%), Gaps = 11/146 (7%) Query: 690 GSFAISFRTEKEIKHCRVKQEGRLYTIGTVK-FESLIELVSYYENHPLYKKVKLWYPISE 748 GS + R E+KH ++ LY I K F L+ELV +Y+ + L K + + Sbjct: 24 GSRQETRRYNVEVKHIKIMTSEGLYRITEKKAFRGLLELVEFYQQNSL----KDCFKSLD 79 Query: 749 ETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDK 808 T++ EP+ + P T + T KA YD+ AR ELS + II ++K Sbjct: 80 TTLQFPYKEPERRAISKPPA--GSTKYFG--TAKARYDFCARDRSELSLKEGDIIKILNK 135 Query: 809 P-DEGWWRGDYGGKRHHWFPANYVLE 833 +GWWRG+ G R WFP+NYV E Sbjct: 136 KGQQGWWRGEIYG-RIGWFPSNYVEE 160 >UniRef50_A7SYD1 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 245 Score = 66.9 bits (156), Expect = 3e-09 Identities = 29/53 (54%), Positives = 36/53 (67%) Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 VT ALYDY+ D+E++F IITN+++ DEGWWRG RH FPANYV Sbjct: 189 VTATALYDYQQADDNEITFDPDDIITNIEQIDEGWWRGTGPDGRHGMFPANYV 241 >UniRef50_A2VCM4 Cluster: PLCH2 protein; n=6; Tetrapoda|Rep: PLCH2 protein - Homo sapiens (Human) Length = 368 Score = 66.9 bits (156), Expect = 3e-09 Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 15/221 (6%) Query: 102 CFTIYYGTEFKLRCASFVAQTDKECEAWVKGVLYLIA----EAVSASYPLQIERWLRKEF 157 CF+IY+G+ + V+ + + WV G+ YL+A E A ++WL++ F Sbjct: 6 CFSIYHGSHRE--SLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTF 63 Query: 158 YSIE-NSHEKITLKEVKAFLPKINCKISTSKLRDVFQDVDT-EKRGEIGFDDFAVLYQKL 215 + N +++ EV L K+N + +++ +F++ DT + +G +GF++F Y+ + Sbjct: 64 DEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMM 123 Query: 216 IFDENNVQDIFDKYSVYCSNGTTITLREFQNFLRDEQHDNLGDDEVQASQFIRDYLRDPQ 275 + +D++ Y ++ + Q FL+ EQ + +++ Q I + Sbjct: 124 ----STRRDLYLLMLTYSNHKDHLDAASLQRFLQVEQ--KMAGVTLESCQDIIEQFEPCP 177 Query: 276 RDIYEPYFTLSEFVEMLYSKQNSIYDSQYDKVTQDMT-RPL 315 + + + F S I++ ++ V QDMT RPL Sbjct: 178 ENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMTQRPL 218 >UniRef50_A2AAH7 Cluster: Growth factor receptor bound protein 2; n=3; Mammalia|Rep: Growth factor receptor bound protein 2 - Mus musculus (Mouse) Length = 203 Score = 66.5 bits (155), Expect = 4e-09 Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 1/78 (1%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715 WF R +AEE+L K DGAFL+R SE G F++S + +++H +V ++G Y Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 716 IGTVKFESLIELVSYYEN 733 + VKF SL ELV Y+ + Sbjct: 120 LWVVKFNSLNELVDYHRS 137 Score = 51.2 bits (117), Expect = 2e-04 Identities = 38/111 (34%), Positives = 61/111 (54%), Gaps = 9/111 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WF GK+ R +AE++L H DG FL+RES + GD+ LS V H ++ L+ Sbjct: 60 WFFGKIP--RAKAEEMLSKQRH--DGAFLIRESESAPGDFSLSVKFGNDVQHFKV-LRD- 113 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL-RSQEFLITLKEPVPQPNKHEG 654 G K++L + F+SL L+ ++RS + R+Q+ + E +PQ + G Sbjct: 114 -GAGKYFLW-VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQMPQEDGELG 162 Score = 38.3 bits (85), Expect = 1.3 Identities = 18/50 (36%), Positives = 31/50 (62%), Gaps = 2/50 (4%) Query: 783 ALYDYRARQDDELSFCKHAIITNVDKP-DEGWWRGDYGGKRHHWFPANYV 831 A YD++A DDELSF + I+ +++ D+ W++ + GK + P NY+ Sbjct: 5 AKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGK-DGFIPKNYI 53 >UniRef50_Q0UVW3 Cluster: Putative uncharacterized protein; n=3; Pezizomycotina|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 819 Score = 66.5 bits (155), Expect = 4e-09 Identities = 31/56 (55%), Positives = 38/56 (67%), Gaps = 1/56 (1%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +S T ALYDY A +D+E+SF ++A IT V+ PDE WW G Y GK FPANYV Sbjct: 761 SSGPTATALYDYEAAEDNEISFPENATITGVEFPDEDWWLGSYNGK-SGLFPANYV 815 Score = 46.0 bits (104), Expect = 0.006 Identities = 19/51 (37%), Positives = 27/51 (52%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 YDY +D+E+ + +T++D DE WW G FPANYV +E Sbjct: 677 YDYEKAEDNEVELREGEYVTDIDMVDEDWWMGTNSQGERGLFPANYVELVE 727 >UniRef50_A6SRW9 Cluster: Putative uncharacterized protein; n=1; Botryotinia fuckeliana B05.10|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 489 Score = 66.5 bits (155), Expect = 4e-09 Identities = 79/272 (29%), Positives = 121/272 (44%), Gaps = 39/272 (14%) Query: 933 RIAKEISDLIIYCRS---VTFNIERLRIKGFVYNEMSSFPETKAERLMSQQENTFFVKYH 989 +I + +S L IY S V+F++ ++ S E L Q+ F +++ Sbjct: 210 KICESLSKLGIYTHSEHFVSFDVRAATKPSHIF----SVGEKVINELHEQKREQMF-QHN 264 Query: 990 TTQLSRIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFIL 1049 R +P G R DSSN +P W G QMVALN+QT D+ M +N G F G G++L Sbjct: 265 RNFFMRAFPAGSRFDSSNLDPSVCWRKGIQMVALNWQTLDEGMMLNEGMFA--GSQGWLL 322 Query: 1050 KPQFMFEEGYNPCDKKS-IEGKVKPVTVMLRV-IGARHLCKTGRGTAS----PFVEVEI- 1102 KP GY D+KS I + T+ L++ I A G P+V+ E+ Sbjct: 323 KP-----PGYRSEDEKSDIWANIPYKTLDLKITIFAGQQIPYPEGETEKGFHPYVKCELH 377 Query: 1103 -----------IGADYDSGV-KLVTKTVSDNGLNP-LWNDICEFE-VAN--PELALIRFV 1146 IG D + + KT +G P + FE + N EL+ +RF Sbjct: 378 VESQEELNGQPIGNDVKAKEGEHKLKTAYKSGSKPDFEGETLHFEGIRNVVEELSFVRFK 437 Query: 1147 VQDEDIFGEPNFIGQATFPLLCLRKGYRSVPL 1178 ++D + + + A L L++GYR +PL Sbjct: 438 IEDAN-YSKDELAAWACIRLDRLQQGYRLIPL 468 Score = 55.2 bits (127), Expect = 1e-05 Identities = 27/70 (38%), Positives = 40/70 (57%) Query: 363 GTPFIYHGHTLTTKIRFMDVLRTIKEHAFITSEYPLILSIEDNCSLPQQRRMASAFQDVF 422 G P + HG TLT + F V +TI+E+AF TS P+I+S+E + QQ M ++ + Sbjct: 49 GEPLVLHGWTLTAPVGFRAVCKTIRENAFTTSPLPIIVSLEVHADHEQQEVMVDIMKEEW 108 Query: 423 GDLLLVHPMD 432 LLL P + Sbjct: 109 EGLLLDSPFE 118 >UniRef50_Q5ZM15 Cluster: Putative uncharacterized protein; n=3; Gallus gallus|Rep: Putative uncharacterized protein - Gallus gallus (Chicken) Length = 431 Score = 66.1 bits (154), Expect = 5e-09 Identities = 52/160 (32%), Positives = 77/160 (48%), Gaps = 12/160 (7%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH ++G EAE LL G+FL R S + GD+ LS R +V H +I Q Sbjct: 4 WFHPNISGI--EAEKLLLTRGV--HGSFLARPSKSNPGDFTLSVRRNDEVTHIKI---QN 56 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHP--LRSQEF-LITLKEPVPQPNKHEGKEWFHAH 661 G + L F L+ +Y LR + +I LK P+ + + W+H H Sbjct: 57 TG-DYYDLYGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLNCQDP-TSERWYHGH 114 Query: 662 CTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKE 701 T +AE+LL + G+FLVR S+ + G F +S T ++ Sbjct: 115 LTGKEAEKLLTEKGKPGSFLVRESQSKPGDFVLSVLTNED 154 Score = 61.7 bits (143), Expect = 1e-07 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 7/98 (7%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716 WFH + + +AE+LL G+FL RPS+ G F +S R E+ H +++ G Y + Sbjct: 4 WFHPNISGIEAEKLLLTRGVHGSFLARPSKSNPGDFTLSVRRNDEVTHIKIQNTGDYYDL 63 Query: 717 -GTVKFESLIELVSYY-ENHPLYKK-----VKLWYPIS 747 G KF ELV YY E L ++ ++L YP++ Sbjct: 64 YGGEKFARKPELVQYYTEQQGLLREKNSNVIELKYPLN 101 Score = 37.1 bits (82), Expect = 2.9 Identities = 22/46 (47%), Positives = 28/46 (60%), Gaps = 4/46 (8%) Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLS 587 +E W+HG L G +EAE LL G+FLVRES + GD+ LS Sbjct: 107 SERWYHGHLTG--KEAEKLLTEKGK--PGSFLVRESQSKPGDFVLS 148 >UniRef50_Q4RFY9 Cluster: Chromosome undetermined SCAF15108, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF15108, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 877 Score = 66.1 bits (154), Expect = 5e-09 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 28/184 (15%) Query: 664 RTQAE-ELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV-KQEGRLYTIGTVKF 721 R QAE EL+ + N+ +LVR +E +AIS + ++KH ++ +EG Y KF Sbjct: 692 RLQAEAELINRVNS--TYLVRHRSREYTEYAISIKYNNDVKHIKILTKEGCFYIAENKKF 749 Query: 722 ESLIELVSYYENHPLYKKVK-----LWYPIS--EETVRRLVSEPDDNT------VYGTPG 768 S+ EL+ YY++H L + + L +P E + ++ P N + PG Sbjct: 750 RSISELIEYYKHHSLREGFRSLDTTLHFPYRELENAAMQRLNRPGSNNPLLCGLSFVPPG 809 Query: 769 Y--MDPTS--FTSKVTVK------ALYDYRARQDDELSFCKHAIITNVDKPD-EGWWRGD 817 Y + P+S F S +T K A YD+ +R ELS + ++ K GWWRG+ Sbjct: 810 YSFVPPSSAPFWSVLTPKVIGVAIARYDFSSRDTRELSLQEGDVVKIYTKSGANGWWRGE 869 Query: 818 YGGK 821 G+ Sbjct: 870 VHGR 873 >UniRef50_Q5AS57 Cluster: Putative uncharacterized protein; n=1; Emericella nidulans|Rep: Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans) Length = 784 Score = 66.1 bits (154), Expect = 5e-09 Identities = 33/61 (54%), Positives = 42/61 (68%), Gaps = 2/61 (3%) Query: 772 PTSFTS-KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830 PTS + K T KALYDY A +D+ELSF + A I N++ PD+ WW G++ GK FPANY Sbjct: 721 PTSGSHVKPTAKALYDYEAAEDNELSFPEGAEIINIEFPDDDWWLGEFRGKT-GLFPANY 779 Query: 831 V 831 V Sbjct: 780 V 780 Score = 41.1 bits (92), Expect = 0.18 Identities = 16/51 (31%), Positives = 26/51 (50%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 YDY +D+E+ + +T ++ D+ WW G FP+NYV +E Sbjct: 644 YDYEKAEDNEVDLREGEFVTEIEMVDKDWWLGSNAQGERGLFPSNYVELLE 694 >UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Culicidae|Rep: Tyrosine-protein kinase shark - Aedes aegypti (Yellowfever mosquito) Length = 939 Score = 65.3 bits (152), Expect = 1e-08 Identities = 44/116 (37%), Positives = 63/116 (54%), Gaps = 10/116 (8%) Query: 544 CWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQ 603 CWFHGK++ R+ AE++LR G+G F+VRES + GD+ LS Q +V H +I+ Sbjct: 8 CWFHGKIS--RERAEEILRQEG--GNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIR--- 60 Query: 604 ERGVTKFYLIDS-MCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKE 656 G F+ ID M L +LI HYR S+ L ++ + P P + GKE Sbjct: 61 RHGDDAFFSIDDHMPIHGLDSLIEHYRESSNGLVTRLQTVCQSGPPPHDVRSHGKE 116 Score = 54.8 bits (126), Expect = 1e-05 Identities = 22/62 (35%), Positives = 37/62 (59%) Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709 N+ E WFH +R +AEE+LR+ +G F+VR S +G F +S + E+ H ++++ Sbjct: 2 NREENLCWFHGKISRERAEEILRQEGGNGVFMVRESTSSEGDFVLSVLFQDEVVHYQIRR 61 Query: 710 EG 711 G Sbjct: 62 HG 63 >UniRef50_Q0PIN0 Cluster: Bam32; n=1; Branchiostoma belcheri tsingtauense|Rep: Bam32 - Branchiostoma belcheri tsingtauense Length = 250 Score = 65.3 bits (152), Expect = 1e-08 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 3/122 (2%) Query: 653 EGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR 712 E +W+H +R AE LL DG++L+R S G +++S + + +KH ++ +G+ Sbjct: 10 EQLDWYHGDLSRHMAEALLMANAEDGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWDGK 69 Query: 713 LYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPD--DN-TVYGTPGY 769 Y G F+SL E V ++ N PL R V EPD D TV+ + G Sbjct: 70 QYQFGMGVFQSLQEFVEHFANQPLIGGESGILTALRHPYSRNVLEPDVYDTVTVHASLGQ 129 Query: 770 MD 771 D Sbjct: 130 QD 131 Score = 49.6 bits (113), Expect = 5e-04 Identities = 37/103 (35%), Positives = 50/103 (48%), Gaps = 11/103 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG L+ R AE LL A+A DG++L+R S T VG+Y LS + V H +I Sbjct: 14 WYHGDLS--RHMAEALLMANAE--DGSYLLRSSATRVGEYSLSVKCKDSVKHFQIGWD-- 67 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEP 645 K Y F SL + H+ + PL E L L+ P Sbjct: 68 ---GKQYQFGMGVFQSLQEFVEHFANQPLIGGESGILTALRHP 107 >UniRef50_UPI00015B62FA Cluster: PREDICTED: similar to ras gtpase activating protein; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ras gtpase activating protein - Nasonia vitripennis Length = 879 Score = 64.9 bits (151), Expect = 1e-08 Identities = 34/91 (37%), Positives = 53/91 (58%), Gaps = 1/91 (1%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715 +W+H R AEE LR + G++LVR S+++ GS+ +S+ I H R+ Y Sbjct: 76 QWYHGRLDRFTAEERLRDASRLGSYLVRESDRKPGSYVLSYLGRTGINHFRITAVCGDYY 135 Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYP 745 IG +F SL++LV+YY + L KK +L +P Sbjct: 136 IGGRQFNSLMDLVAYYTHCSDLLKKERLIHP 166 Score = 58.0 bits (134), Expect = 1e-06 Identities = 30/103 (29%), Positives = 56/103 (54%), Gaps = 9/103 (8%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716 WFH + T+++A ++L K G+FLVRPS+ G +++ F +I+ R++++G Y + Sbjct: 246 WFHPNVTKSEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 304 Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPD 759 G FE L +++ Y + + V+ +V+EPD Sbjct: 305 GGRTFECLDAVINRYRKEQIVE--------GHTLVQAMVTEPD 339 Score = 48.8 bits (111), Expect = 9e-04 Identities = 39/106 (36%), Positives = 55/106 (51%), Gaps = 11/106 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG+L +R AE+ LR + LG ++LVRES G Y LS+ + +NH RI Sbjct: 77 WYHGRL--DRFTAEERLRDASRLG--SYLVRESDRKPGSYVLSYLGRTGINHFRI----- 127 Query: 605 RGVTKFYLIDSMCFDSLYNLITHY-RSHPLRSQEFLITLKEPVPQP 649 V Y I F+SL +L+ +Y L +E LI P P+P Sbjct: 128 TAVCGDYYIGGRQFNSLMDLVAYYTHCSDLLKKERLIH-PTPPPEP 172 Score = 45.2 bits (102), Expect = 0.011 Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH + + EA D+L G G+FLVR S GDY L F ++ RI+ K Sbjct: 246 WFHPNVT--KSEAVDML---VKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 300 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEGKEWFHA 660 R YL+ F+ L +I YR + L+ P KE HA Sbjct: 301 R-----YLMGGRTFECLDAVINRYRKEQIVEGHTLVQAMVTEPDGTVRVNKEVQHA 351 >UniRef50_Q4SVL5 Cluster: Chromosome undetermined SCAF13756, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF13756, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 450 Score = 64.9 bits (151), Expect = 1e-08 Identities = 35/77 (45%), Positives = 45/77 (58%), Gaps = 5/77 (6%) Query: 756 SEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWR 815 ++ DD +Y P + TS V +ALYDY+A D E+SF +IT ++ DEGWWR Sbjct: 375 AQVDDTNLYEVPA--EETS-DKGVCARALYDYQAADDTEISFDPDEVITGIEMIDEGWWR 431 Query: 816 GDYGGKRHH-WFPANYV 831 G YG H FPANYV Sbjct: 432 G-YGPDGHFGMFPANYV 447 >UniRef50_Q9UN19 Cluster: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide; n=25; Euteleostomi|Rep: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide - Homo sapiens (Human) Length = 280 Score = 64.9 bits (151), Expect = 1e-08 Identities = 32/102 (31%), Positives = 51/102 (50%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716 W+H + TR AE LL DG++L+R S + G +++S R + +KH V+ G + Sbjct: 35 WYHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGYSFKF 94 Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEP 758 G +F SL + V ++ N PL + + R V EP Sbjct: 95 GFNEFSSLKDFVKHFANQPLIGSETGTLMVLKHPYPRKVEEP 136 Score = 42.3 bits (95), Expect = 0.077 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 11/106 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG L R AE LL ++ DG++L+R+S G Y LS + V H ++ Sbjct: 35 WYHGNLT--RHAAEALLLSNGC--DGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYTGY 90 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQE--FLITLKEPVPQ 648 KF + F SL + + H+ + PL E L+ LK P P+ Sbjct: 91 S--FKFGFNE---FSSLKDFVKHFANQPLIGSETGTLMVLKHPYPR 131 >UniRef50_A2QHI3 Cluster: Contig An03c0200, complete genome; n=3; Trichocomaceae|Rep: Contig An03c0200, complete genome - Aspergillus niger Length = 782 Score = 64.5 bits (150), Expect = 2e-08 Identities = 30/52 (57%), Positives = 37/52 (71%), Gaps = 1/52 (1%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T ALYDY A +D+ELSF + A ITN++ PD+ WW G+Y GK FPANYV Sbjct: 728 TATALYDYEAAEDNELSFPEGAEITNIEFPDDDWWFGEYLGKM-GLFPANYV 778 Score = 44.0 bits (99), Expect = 0.025 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 2/53 (3%) Query: 781 VKAL--YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +KAL YDY +D+E+ + +TN++ D+ WW G FP+NYV Sbjct: 630 IKALVQYDYEKAEDNEIELKEGEYVTNIEMVDQDWWLGSNAQGDRGLFPSNYV 682 >UniRef50_A2RUZ0 Cluster: Zgc:158474 protein; n=4; Euteleostomi|Rep: Zgc:158474 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 906 Score = 64.1 bits (149), Expect = 2e-08 Identities = 35/93 (37%), Positives = 55/93 (59%), Gaps = 7/93 (7%) Query: 542 AEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIK 600 +EC WFHG L+ R +A L+ A G FLVR+S T G+Y L+F QGK H R+ Sbjct: 711 SECQWFHGTLS--RLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLS 768 Query: 601 LKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 L ++ G + + + F S+++++ H+R HP+ Sbjct: 769 LNED-GQCR---VQHLWFQSIFDMLEHFRVHPI 797 Score = 48.4 bits (110), Expect = 0.001 Identities = 23/84 (27%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Query: 656 EWFHAHCTRTQAEELLRKTN--TDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGR 712 +WFH +R +A +L+ + G FLVR SE +G + ++F + + KH R+ E Sbjct: 714 QWFHGTLSRLKAAQLVLAGGMASHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEDG 773 Query: 713 LYTIGTVKFESLIELVSYYENHPL 736 + + F+S+ +++ ++ HP+ Sbjct: 774 QCRVQHLWFQSIFDMLEHFRVHPI 797 >UniRef50_Q9P7E8 Cluster: Protein app1; n=2; Fungi/Metazoa group|Rep: Protein app1 - Schizosaccharomyces pombe (Fission yeast) Length = 857 Score = 64.1 bits (149), Expect = 2e-08 Identities = 30/55 (54%), Positives = 39/55 (70%), Gaps = 1/55 (1%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 +VKA+YDY+A++D+ELSF + II NVD D WW G+ G R FP+NYV EI Sbjct: 804 SVKAIYDYQAQEDNELSFFEDEIIANVDCVDPNWWEGECHGHR-GLFPSNYVEEI 857 Score = 45.2 bits (102), Expect = 0.011 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 1/86 (1%) Query: 777 SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836 +K +YDY +++E+ ++ I ++ D+GWW G+ + FP+NYV EI Sbjct: 726 TKTPAIVIYDYSPEEENEIELVENEQIQILEFVDDGWWLGENSKGQQGLFPSNYV-EITG 784 Query: 837 PHTPDVTSGLENESAALGSLQKGVLD 862 P+ E ++ G K + D Sbjct: 785 PNETANNPPAEPQAGGPGKSVKAIYD 810 >UniRef50_Q8IR23 Cluster: CG9209-PA, isoform A; n=6; Endopterygota|Rep: CG9209-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 954 Score = 63.7 bits (148), Expect = 3e-08 Identities = 28/90 (31%), Positives = 52/90 (57%), Gaps = 1/90 (1%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716 WFH +CT+ +A ++L K G+FLVRPS+ G +++ F +I+ R++++G Y + Sbjct: 253 WFHPNCTKNEAVDMLVKAGP-GSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLM 311 Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPI 746 G FE L +++ Y + + L +P+ Sbjct: 312 GGRTFECLDAVINRYRKEQIVEGHSLNHPV 341 Score = 59.3 bits (137), Expect = 6e-07 Identities = 32/93 (34%), Positives = 52/93 (55%), Gaps = 1/93 (1%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYT 715 EW+H R AE LR ++ G++LVR S+++ GS+ +S+ I H R+ + Sbjct: 83 EWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFY 142 Query: 716 IGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747 IG +F SL +LV YY + L K+ +L P++ Sbjct: 143 IGGRQFISLSDLVGYYTSCSDLLKRERLAIPVA 175 Score = 48.4 bits (110), Expect = 0.001 Identities = 37/109 (33%), Positives = 55/109 (50%), Gaps = 11/109 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG+L +R AE LR + LG ++LVRES G Y LS++ + +NH RI Sbjct: 84 WYHGRL--DRYSAESRLRGSSKLG--SYLVRESDRKPGSYVLSYYGRTGINHFRI----- 134 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNK 651 V + I F SL +L+ +Y S L+ + I + P P +K Sbjct: 135 TAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDK 183 Score = 41.5 bits (93), Expect = 0.13 Identities = 31/89 (34%), Positives = 40/89 (44%), Gaps = 10/89 (11%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH N EA D+L G G+FLVR S GDY L F ++ RI+ K Sbjct: 253 WFHPNCTKN--EAVDML---VKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGV 307 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 R YL+ F+ L +I YR + Sbjct: 308 R-----YLMGGRTFECLDAVINRYRKEQI 331 >UniRef50_Q7SXH4 Cluster: Cortactin, like; n=3; Danio rerio|Rep: Cortactin, like - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 206 Score = 63.3 bits (147), Expect = 4e-08 Identities = 30/53 (56%), Positives = 36/53 (67%), Gaps = 1/53 (1%) Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +T ALYDY+A DDE+SF IITN++ DEGWWRG G + FPANYV Sbjct: 151 ITAVALYDYQAAGDDEISFDPDDIITNIEMIDEGWWRGVCRG-AYGLFPANYV 202 >UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF5507, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1116 Score = 63.3 bits (147), Expect = 4e-08 Identities = 36/98 (36%), Positives = 51/98 (52%), Gaps = 3/98 (3%) Query: 657 WFHAHCTRTQAEE-LLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ--EGRL 713 WF R QA+ LL N++GAFL+R SEK+ + +S R+ ++KH +V Q + R Sbjct: 69 WFFGTLNRLQAQSHLLAPENSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRF 128 Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETV 751 Y +F SL ELV YY+ L L P T+ Sbjct: 129 YVEPGRRFSSLAELVDYYQKTSLNNAGPLGNPCKRNTL 166 Score = 59.7 bits (138), Expect = 5e-07 Identities = 32/96 (33%), Positives = 55/96 (57%), Gaps = 3/96 (3%) Query: 657 WFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQE--GRL 713 W++ + R +AE+LL + N DG+FLVR SE + IS R+E ++ H R+++ G Sbjct: 250 WYYGNINRVKAEKLLLASQNKDGSFLVRISESHSDEYTISARSEGKVFHFRIQRSSIGAY 309 Query: 714 YTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEE 749 + + F +L EL+SYY+ + V L P +++ Sbjct: 310 FVSDRISFATLGELISYYQRNNRSLGVLLEEPCAQQ 345 Score = 54.4 bits (125), Expect = 2e-05 Identities = 29/79 (36%), Positives = 43/79 (54%), Gaps = 2/79 (2%) Query: 675 NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ--EGRLYTIGTVKFESLIELVSYYE 732 N++GAFL+R SEK+ + +S R+ ++KH +V Q + R Y +F SL ELV YY+ Sbjct: 733 NSEGAFLIRVSEKDNVGYVLSVRSGDQVKHYKVLQTDQNRFYVEPGRRFSSLAELVDYYQ 792 Query: 733 NHPLYKKVKLWYPISEETV 751 L L P T+ Sbjct: 793 KTSLNNAGPLGNPCKRNTL 811 Score = 52.0 bits (119), Expect = 1e-04 Identities = 35/104 (33%), Positives = 59/104 (56%), Gaps = 9/104 (8%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W++G + NR +AE LL A + DG+FLVR S + +Y +S +GKV H RI Q Sbjct: 250 WYYGNI--NRVKAEKLLLASQNK-DGSFLVRISESHSDEYTISARSEGKVFHFRI---QR 303 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQ 648 + +++ D + F +L LI++Y+ + ++ + L+EP Q Sbjct: 304 SSIGAYFVSDRISFATLGELISYYQRN---NRSLGVLLEEPCAQ 344 >UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 511 Score = 63.3 bits (147), Expect = 4e-08 Identities = 30/86 (34%), Positives = 48/86 (55%), Gaps = 2/86 (2%) Query: 653 EGKEWFHAHCTRTQA-EELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEG 711 E + WF R A L+ N G+FLVR SE + + +S RT++ KH ++ Q G Sbjct: 130 ESQPWFFGKMNRVGAVSHLMSDENNYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTG 189 Query: 712 -RLYTIGTVKFESLIELVSYYENHPL 736 + Y KF S++E++ +Y++HPL Sbjct: 190 DQFYVDALFKFSSIVEVIEHYQSHPL 215 Score = 40.7 bits (91), Expect = 0.24 Identities = 38/114 (33%), Positives = 54/114 (47%), Gaps = 12/114 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WF GK+ NR A L + + G+FLVR S + Y LS + H +I + Sbjct: 134 WFFGKM--NRVGAVSHLMSDEN-NYGSFLVRVSESDDMGYVLSVRTKENAKHFKIFQTGD 190 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFL----ITLK-EPVPQPNKHE 653 + FY+ F S+ +I HY+SHPL + L I +K E VP P+ E Sbjct: 191 Q----FYVDALFKFSSIVEVIEHYQSHPLSIGDLLSEPCIRIKPENVPPPSTDE 240 >UniRef50_Q86F73 Cluster: Clone ZZD1053 mRNA sequence; n=1; Schistosoma japonicum|Rep: Clone ZZD1053 mRNA sequence - Schistosoma japonicum (Blood fluke) Length = 234 Score = 63.3 bits (147), Expect = 4e-08 Identities = 53/186 (28%), Positives = 86/186 (46%), Gaps = 29/186 (15%) Query: 657 WFHAHCTRTQAEELLRKTNT--------DGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK 708 W+ HC+R +AEE L++ + DGAF++R SE + F++S + E+ H +V Sbjct: 60 WYIRHCSRMEAEERLQEVDQETAQHLQPDGAFILRQSEADGKGFSLSVKQGCEVLHFKVL 119 Query: 709 Q-EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTP 767 Q E Y +F+S+ +L+ + ++K IS + LV P Sbjct: 120 QDEAGKYFFWISRFDSVNQLIDH------HRKTS----ISRNRLLTLVDL--------VP 161 Query: 768 GYMDPTSFTSKV--TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHW 825 PT+ V A +D+ + ELS + +I +++ DE WWRG R Sbjct: 162 SKRFPTNVRKYQLDRVIARFDFITKDAGELSLHRGDVIEVINRDDENWWRGRTSDGRCGL 221 Query: 826 FPANYV 831 FP+NYV Sbjct: 222 FPSNYV 227 >UniRef50_Q2UPV5 Cluster: Predicted protein; n=2; Pezizomycotina|Rep: Predicted protein - Aspergillus oryzae Length = 218 Score = 63.3 bits (147), Expect = 4e-08 Identities = 59/203 (29%), Positives = 97/203 (47%), Gaps = 26/203 (12%) Query: 995 RIYPKGQRIDSSNYNPVPFWNCGSQMVALNYQTPDKPMQVNMGKFKQNGGCGFILKPQ-F 1053 RIYP G R++SSN +P FW G+Q+VALN+Q DK M +N F G++LKPQ + Sbjct: 2 RIYPYGLRVNSSNLDPSFFWRRGAQVVALNWQNLDKGMMLNSAMFADEQ--GWVLKPQGY 59 Query: 1054 MFEEGYNPCDKKSIEGKVKPVTVMLRVIGARH----------LC----KTGRGTASPFVE 1099 + + + ++ ++ ++ + + H +C +T T SP E Sbjct: 60 LSSDAPSTIVRRQLDLSIEFLAGQNIPLPPGHTNEKHFHPYVVCDLHVETPEDTTSPHTE 119 Query: 1100 VEIIGADYDSGVKLVTKTVSDNGLNP-LWNDICEFEVAN---PELALIRFVVQDEDIFGE 1155 E G K + K+ S G +P + +F + EL+ +RF ++D++ FG Sbjct: 120 DE--GESETENHKQMIKSAS--GASPDFEGQMVQFPTLSGLVEELSFVRFKIKDDE-FGR 174 Query: 1156 PNFIGQATFPLLCLRKGYRSVPL 1178 + A L L++GYR V L Sbjct: 175 DSTAAWACIRLDRLQEGYRLVHL 197 >UniRef50_Q14247 Cluster: Src substrate cortactin; n=44; Bilateria|Rep: Src substrate cortactin - Homo sapiens (Human) Length = 550 Score = 63.3 bits (147), Expect = 4e-08 Identities = 30/52 (57%), Positives = 36/52 (69%), Gaps = 1/52 (1%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T ALYDY+A DDE+SF IITN++ D+GWWRG G R+ FPANYV Sbjct: 496 TAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKG-RYGLFPANYV 546 >UniRef50_UPI0000E1F7BD Cluster: PREDICTED: nitric oxide synthase trafficking isoform 4; n=2; Catarrhini|Rep: PREDICTED: nitric oxide synthase trafficking isoform 4 - Pan troglodytes Length = 563 Score = 62.9 bits (146), Expect = 5e-08 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788 E + VK+ P + + +VS+ PG P ++++ KALY ++ Sbjct: 449 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 507 Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 ARQDDEL+ K I+ +K +EGWW G GK+ H FPA YV E+ Sbjct: 508 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 552 >UniRef50_A7SCW1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 275 Score = 62.9 bits (146), Expect = 5e-08 Identities = 44/175 (25%), Positives = 72/175 (41%), Gaps = 28/175 (16%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLYTI 716 W+H R + E +L G +LVR S G + +S ++ H + +G +YTI Sbjct: 9 WYHGVLKRVETEGILNG-KPPGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNKGTMYTI 67 Query: 717 GTVKFESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFT 776 G F L ++ +Y+ H L T++ V + N Sbjct: 68 GDQTFPDLPSIIEFYKKHFL----------DTTTLKEHVPNSECN--------------- 102 Query: 777 SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 + VKALY + + D++L F K I+T + K ++ WW+ R P YV Sbjct: 103 --IKVKALYAFPGKDDEDLPFKKGDILTVISKEEDNWWKARDSAGREGMIPKPYV 155 Score = 50.8 bits (116), Expect = 2e-04 Identities = 39/103 (37%), Positives = 48/103 (46%), Gaps = 14/103 (13%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 W+HG L R E E +L G +LVR+S T GDY LS GKV+H I K Sbjct: 9 WYHGVL--KRVETEGILNGKP---PGVWLVRDSTTIPGDYVLSVSESGKVSHYIINNK-- 61 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVP 647 Y I F L ++I Y+ H L + TLKE VP Sbjct: 62 ---GTMYTIGDQTFPDLPSIIEFYKKHFLDT----TTLKEHVP 97 >UniRef50_Q8IVI9 Cluster: Nostrin; n=22; Tetrapoda|Rep: Nostrin - Homo sapiens (Human) Length = 506 Score = 62.9 bits (146), Expect = 5e-08 Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 5/106 (4%) Query: 732 ENHPLYKKVKLWYPISEETVRRLVSEPDDNTVYGTPGYMDPTSFTSKVT---VKALYDYR 788 E + VK+ P + + +VS+ PG P ++++ KALY ++ Sbjct: 392 EKEHTHSYVKISRPFLMKRLENIVSKASSGG-QSNPGSSTPAPGAAQLSSRLCKALYSFQ 450 Query: 789 ARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 ARQDDEL+ K I+ +K +EGWW G GK+ H FPA YV E+ Sbjct: 451 ARQDDELNLEKGDIVIIHEKKEEGWWFGSLNGKKGH-FPAAYVEEL 495 >UniRef50_UPI00015B58E2 Cluster: PREDICTED: similar to signal transduction protein lnk-realted; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to signal transduction protein lnk-realted - Nasonia vitripennis Length = 458 Score = 62.5 bits (145), Expect = 7e-08 Identities = 33/89 (37%), Positives = 54/89 (60%), Gaps = 6/89 (6%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG L R +A L+ +A G GTFLVR+S T G+Y L+F QG+ H R+ L + Sbjct: 270 WFHGTLP--RSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRMTL-TD 326 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 +G + + + F ++Y+++ H+R +P+ Sbjct: 327 QGHCR---VQHLSFPAIYDMLDHFRQNPI 352 Score = 44.8 bits (101), Expect = 0.014 Identities = 21/83 (25%), Positives = 44/83 (53%), Gaps = 3/83 (3%) Query: 657 WFHAHCTRTQAEELLRKTNTDG--AFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGRLY 714 WFH R+ A +L+ T+G FLVR SE +G + ++F + KH R+ + + Sbjct: 270 WFHGTLPRSDAAQLVLHNATEGHGTFLVRQSETRKGEYVLTFNFQGRAKHLRMTLTDQGH 329 Query: 715 -TIGTVKFESLIELVSYYENHPL 736 + + F ++ +++ ++ +P+ Sbjct: 330 CRVQHLSFPAIYDMLDHFRQNPI 352 >UniRef50_Q6GMH1 Cluster: Zgc:91835; n=1; Danio rerio|Rep: Zgc:91835 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 496 Score = 62.5 bits (145), Expect = 7e-08 Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Query: 764 YGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRH 823 + +P + + +ALYDY+A D E+SF +I+ +D DEGWWRG YG H Sbjct: 426 FQSPADEEENGDNQNICARALYDYQASDDTEISFDPDDVISGIDMIDEGWWRG-YGPDGH 484 Query: 824 H-WFPANYV 831 + FPANYV Sbjct: 485 YGMFPANYV 493 >UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti (Yellowfever mosquito) Length = 747 Score = 62.1 bits (144), Expect = 9e-08 Identities = 37/84 (44%), Positives = 46/84 (54%), Gaps = 9/84 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG++ R+EAE+LL+ DG FLVRES F GDY L KV H RIK + Sbjct: 378 WFHGRI--KREEAENLLKPRE---DGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAE- 431 Query: 605 RGVTKFYLIDSMCFDSLYNLITHY 628 K + D FD+L L+ HY Sbjct: 432 ---NKLTIDDDEYFDNLGQLVEHY 452 Score = 48.4 bits (110), Expect = 0.001 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRLYT 715 WFH R +AE LL K DG FLVR S G + + ++++H R+K E +L Sbjct: 378 WFHGRIKREEAENLL-KPREDGLFLVRESTNFPGDYTLCVCFNEKVEHYRIKYAENKLTI 436 Query: 716 IGTVKFESLIELVSYY 731 F++L +LV +Y Sbjct: 437 DDDEYFDNLGQLVEHY 452 >UniRef50_A1C8D2 Cluster: Actin binding protein, putative; n=4; Eurotiomycetidae|Rep: Actin binding protein, putative - Aspergillus clavatus Length = 791 Score = 62.1 bits (144), Expect = 9e-08 Identities = 27/49 (55%), Positives = 36/49 (73%), Gaps = 1/49 (2%) Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 ALYDY A +D+E+SF + A I N++ PD+ WW G+Y GK+ FPANYV Sbjct: 740 ALYDYEAAEDNEVSFPEGAEILNIEFPDDDWWFGEYNGKK-GLFPANYV 787 Score = 40.7 bits (91), Expect = 0.24 Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 2/59 (3%) Query: 780 TVKAL--YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEV 836 TV+A+ YDY +D+E+ + +++++ D+ WW G FP+NYV +E+ Sbjct: 638 TVRAIVQYDYEKAEDNEIDLKEGDYVSDIEMVDKDWWLGSNVHGHRGLFPSNYVELVEL 696 >UniRef50_UPI0000E46C42 Cluster: PREDICTED: similar to Grb14; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Grb14 - Strongylocentrotus purpuratus Length = 756 Score = 61.7 bits (143), Expect = 1e-07 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 4/85 (4%) Query: 652 HEGKEWFHAHCTRTQAEELLRKTN-TDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ- 709 H + WFH+ TR + L K DG FL+R S++ G+F +SF +++KH ++ Sbjct: 655 HMTQPWFHSGLTRDETHALFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQINMV 714 Query: 710 EGRLYTI--GTVKFESLIELVSYYE 732 E +YTI G +F LI+LV +Y+ Sbjct: 715 EDGVYTIDDGGTRFTDLIQLVEFYQ 739 Score = 44.0 bits (99), Expect = 0.025 Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 9/93 (9%) Query: 539 LHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCR 598 +H + WFH L + A L A + DG FL+RES G + LSF KV H + Sbjct: 654 IHMTQPWFHSGLTRDETHA---LFAKQGMVDGMFLIRESQRIPGAFVLSFSHNQKVKHYQ 710 Query: 599 IKLKQERGVTKFYLID--SMCFDSLYNLITHYR 629 I + ++ GV Y ID F L L+ Y+ Sbjct: 711 INMVED-GV---YTIDDGGTRFTDLIQLVEFYQ 739 >UniRef50_Q4RUN4 Cluster: Chromosome 12 SCAF14993, whole genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep: Chromosome 12 SCAF14993, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1136 Score = 61.7 bits (143), Expect = 1e-07 Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 2/114 (1%) Query: 636 QEFLITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAIS 695 +E L P + W+H RT AEE LR+ G++L+R S++ GSF +S Sbjct: 164 EEVAFPLSAPPSNHSPPRMPRWYHGKLDRTIAEERLRQARNPGSYLIRESDRRPGSFVLS 223 Query: 696 FRT-EKEIKHCRVKQEGRLYTIGTVKFESLIELVSYYEN-HPLYKKVKLWYPIS 747 F + + H R+ Y IG +F SL +L+ YY L K KL P++ Sbjct: 224 FLSMTNVVNHFRIIAMCGDYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPVA 277 Score = 53.2 bits (122), Expect = 4e-05 Identities = 22/60 (36%), Positives = 35/60 (58%) Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707 + + HEGK W+H H T+ +A LL +FLVRPS+ G +++ FRT I+ ++ Sbjct: 350 EEDPHEGKVWYHGHITKKEAYNLLMTVGQVCSFLVRPSDNTPGDYSLFFRTNDIIQRFKI 409 Score = 41.5 bits (93), Expect = 0.13 Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 17/163 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQ-GKVNHCRIKLKQ 603 W+HGKL +R AE+ LR + G++L+RES G + LSF VNH RI Sbjct: 185 WYHGKL--DRTIAEERLRQARN--PGSYLIRESDRRPGSFVLSFLSMTNVVNHFRI---- 236 Query: 604 ERGVTKFYLIDSMCFDSLYNLITHYR--SHPLRSQEFLITLKEPVPQPNKHEGKEWFHAH 661 + Y I F SL +LI +Y S L+ ++ L + P P ++ + Sbjct: 237 -IAMCGDYYIGGRRFSSLSDLIGYYSYVSCLLKGEKLLSPVAPPEPVEDRRRVRAIL--P 293 Query: 662 CTRTQAEELLRKTNT--DGAFLVRPSEKEQGSFAIS-FRTEKE 701 T+ + +R+ +T G + +E + G +S RTE++ Sbjct: 294 YTKVPDTDEIRQVSTFLQGDMFIVHNELDDGWMWVSNVRTEEQ 336 >UniRef50_O75791 Cluster: GRB2-related adapter protein 2; n=22; Amniota|Rep: GRB2-related adapter protein 2 - Homo sapiens (Human) Length = 330 Score = 61.7 bits (143), Expect = 1e-07 Identities = 31/89 (34%), Positives = 53/89 (59%), Gaps = 2/89 (2%) Query: 656 EWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LY 714 +WFH +R QAE LL G F++R S+ G F+IS R E +++H +V ++ + Y Sbjct: 57 KWFHEGLSRHQAENLLMGKEV-GFFIIRASQSSPGDFSISVRHEDDVQHFKVMRDNKGNY 115 Query: 715 TIGTVKFESLIELVSYYENHPLYKKVKLW 743 + T KF SL +LV YY + + ++ +++ Sbjct: 116 FLWTEKFPSLNKLVDYYRTNSISRQKQIF 144 Score = 45.6 bits (103), Expect = 0.008 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 1/50 (2%) Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +ALYD+ A +DDEL F ++ +D + WW G K FPANYV Sbjct: 277 RALYDFEALEDDELGFHSGEVVEVLDSSNPSWWTGRLHNKL-GLFPANYV 325 Score = 41.9 bits (94), Expect = 0.10 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 10/110 (9%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFH L+ R +AE+LL G F++R S + GD+ +S + V H ++ ++ Sbjct: 58 WFHEGLS--RHQAENLLMGKEV---GFFIIRASQSSPGDFSISVRHEDDVQHFKV-MRDN 111 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKHEG 654 +G Y + + F SL L+ +YR++ + S++ I L++ + H G Sbjct: 112 KG---NYFLWTEKFPSLNKLVDYYRTNSI-SRQKQIFLRDRTREDQGHRG 157 >UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein tyrosine kinase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to protein tyrosine kinase - Nasonia vitripennis Length = 739 Score = 61.3 bits (142), Expect = 2e-07 Identities = 41/108 (37%), Positives = 56/108 (51%), Gaps = 7/108 (6%) Query: 544 CWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQ 603 CWFHG L+ R++AE LL +GTFLVRES + +GDY LS G+V H +I+ Sbjct: 8 CWFHGNLS--REDAESLLLEDGR-DNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIR--- 61 Query: 604 ERGVTKFYLI-DSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650 + G F+ I D L LI +Y+ R L T +P P+ Sbjct: 62 KHGEDAFFSIDDETTIHGLETLIEYYQKENDRLVTILQTPIRGLPPPH 109 Score = 46.4 bits (105), Expect = 0.005 Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 4/80 (5%) Query: 657 WFHAHCTRTQAEELLRKTNTD-GAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR--L 713 WFH + +R AE LL + D G FLVR S G + +S + E+ H ++++ G Sbjct: 9 WFHGNLSREDAESLLLEDGRDNGTFLVRESSSSLGDYVLSVLHDGEVAHYQIRKHGEDAF 68 Query: 714 YTI-GTVKFESLIELVSYYE 732 ++I L L+ YY+ Sbjct: 69 FSIDDETTIHGLETLIEYYQ 88 Score = 44.8 bits (101), Expect = 0.014 Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 2/102 (1%) Query: 648 QPNKHEGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR 706 +P K + +W+H R +A LL K + DG+FLVR SE+ G ++ K H + Sbjct: 274 RPTKEKASDWYHGTLDRMEAINLLHKNGDLDGSFLVRLSERHDGIRVLTVMYNKTPYHFQ 333 Query: 707 V-KQEGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPIS 747 + K+ L+ SL ++ +Y P L +PI+ Sbjct: 334 IQKRRNFLFIDNGPYLPSLEHVIEHYRCMPDGLPGPLIHPIA 375 >UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to Abl tyrosine kinase CG4032-PA - Apis mellifera Length = 1439 Score = 60.9 bits (141), Expect = 2e-07 Identities = 40/116 (34%), Positives = 58/116 (50%), Gaps = 6/116 (5%) Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709 N E W+H R AE LL + +G+FLVR SE G +IS R E + H R+ + Sbjct: 167 NSLEKHSWYHGRICRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINE 225 Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI---SEETVRRLVSEPDD 760 EG+++ KF +L ELV ++ +L YP ++ TV L EPD+ Sbjct: 226 DSEGKMFVTTESKFNTLAELVHHHSMLADGLITQLLYPAPKHNKPTVFPLSPEPDE 281 Score = 48.4 bits (110), Expect = 0.001 Identities = 37/121 (30%), Positives = 58/121 (47%), Gaps = 12/121 (9%) Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590 N + P + L W+HG++ R AE LL + + G+FLVRES + G +S Sbjct: 161 NYVTPVNSLE-KHSWYHGRIC--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 214 Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650 +G+V H RI E K ++ F++L L+ H H + + + L P P+ N Sbjct: 215 EGRVYHYRI---NEDSEGKMFVTTESKFNTLAELVHH---HSMLADGLITQLLYPAPKHN 268 Query: 651 K 651 K Sbjct: 269 K 269 >UniRef50_Q9VDF4 Cluster: CG3637-PA; n=4; Diptera|Rep: CG3637-PA - Drosophila melanogaster (Fruit fly) Length = 559 Score = 60.9 bits (141), Expect = 2e-07 Identities = 27/49 (55%), Positives = 35/49 (71%), Gaps = 1/49 (2%) Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 ALYDY+A DDE+SF +IT+++K D+GWWRG R+ FPANYV Sbjct: 505 ALYDYQAADDDEISFDPDDVITHIEKIDDGWWRG-LCKNRYGLFPANYV 552 >UniRef50_Q9NRF3 Cluster: SH2B adaptor protein 1; n=33; Mammalia|Rep: SH2B adaptor protein 1 - Homo sapiens (Human) Length = 756 Score = 60.9 bits (141), Expect = 2e-07 Identities = 33/89 (37%), Positives = 51/89 (57%), Gaps = 6/89 (6%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG L+ R +A L+ G FLVR+S T G+Y L+F QGK H R+ L +E Sbjct: 527 WFHGMLS--RLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEE 584 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 G + + + F S+++++ H+R HP+ Sbjct: 585 -GQCR---VQHLWFQSIFDMLEHFRVHPI 609 Score = 52.4 bits (120), Expect = 7e-05 Identities = 26/87 (29%), Positives = 50/87 (57%), Gaps = 5/87 (5%) Query: 654 GKEWFHAHCTRTQAEELLRK--TNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCR--VKQ 709 G WFH +R +A +L+ T + G FLVR SE +G + ++F + + KH R + + Sbjct: 524 GYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNE 583 Query: 710 EGRLYTIGTVKFESLIELVSYYENHPL 736 EG+ + + F+S+ +++ ++ HP+ Sbjct: 584 EGQC-RVQHLWFQSIFDMLEHFRVHPI 609 >UniRef50_UPI0000E47D05 Cluster: PREDICTED: similar to MGC84047 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to MGC84047 protein - Strongylocentrotus purpuratus Length = 299 Score = 60.5 bits (140), Expect = 3e-07 Identities = 26/53 (49%), Positives = 34/53 (64%) Query: 779 VTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +T +ALYDY+A D E++F IIT +++ DEGWWRG FPANYV Sbjct: 244 MTARALYDYQAEDDTEVTFDPGDIITQIEQIDEGWWRGQAPSGEFGLFPANYV 296 >UniRef50_UPI000065F033 Cluster: Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2).; n=1; Takifugu rubripes|Rep: Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6) (PAK-interacting exchange factor alpha) (Alpha-Pix) (COOL-2). - Takifugu rubripes Length = 664 Score = 60.5 bits (140), Expect = 3e-07 Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837 ++TVKA ++++ +DELSF K +I + D GWW G GK WFP+NYV EI+ Sbjct: 10 QLTVKARFNFKQNNEDELSFSKGDVIVVTRQEDGGWWEGTLNGKT-GWFPSNYVREIKPC 68 Query: 838 HTPDVTSGLE 847 P G + Sbjct: 69 EKPVSPKGTQ 78 >UniRef50_Q4SAX0 Cluster: Chromosome 3 SCAF14679, whole genome shotgun sequence; n=4; Tetraodontidae|Rep: Chromosome 3 SCAF14679, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 283 Score = 60.5 bits (140), Expect = 3e-07 Identities = 27/50 (54%), Positives = 33/50 (66%), Gaps = 1/50 (2%) Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANY 830 VKALYD+ A +DDELSFC +I +D+ DE WW+G G FPANY Sbjct: 234 VKALYDFTAEEDDELSFCAGDVIDVLDRSDESWWKGRLRG-NSGLFPANY 282 Score = 59.3 bits (137), Expect = 6e-07 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 2/88 (2%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQEGR-LYT 715 WF + +R+ AEELLR G F++R + G F+IS R E +++H +V ++ R Y Sbjct: 58 WFQENASRSAAEELLRHKGV-GEFVIRGCQSSPGEFSISVRHESDVQHFKVMRDSRGQYF 116 Query: 716 IGTVKFESLIELVSYYENHPLYKKVKLW 743 + + KF SL +LV +Y + K +++ Sbjct: 117 LWSEKFTSLNKLVDFYRTSSISKTREIY 144 Score = 39.1 bits (87), Expect = 0.72 Identities = 30/98 (30%), Positives = 48/98 (48%), Gaps = 10/98 (10%) Query: 534 VPQDELHF-AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQG 592 VPQ+ + WF +R AE+LLR H G G F++R + G++ +S + Sbjct: 46 VPQNYIEIQTPRWFQEN--ASRSAAEELLR---HKGVGEFVIRGCQSSPGEFSISVRHES 100 Query: 593 KVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRS 630 V H ++ ++ RG Y + S F SL L+ YR+ Sbjct: 101 DVQHFKV-MRDSRGQ---YFLWSEKFTSLNKLVDFYRT 134 Score = 36.7 bits (81), Expect = 3.8 Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIEVP 837 YD+ A D ELSF K I+ + P++ W++ + G + + P NY+ EI+ P Sbjct: 7 YDFMATGDTELSFRKGDIL-KILSPEDDWFKAEMNG-QEGYVPQNYI-EIQTP 56 >UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p - Drosophila melanogaster (Fruit fly) Length = 847 Score = 60.5 bits (140), Expect = 3e-07 Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 9/86 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG + R EAE LL+ DG FLVRES F GDY L Q KV H R+K + Sbjct: 479 WFHGSIT--RDEAEHLLQPRE---DGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLE- 532 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRS 630 K + D F++L L+ HY + Sbjct: 533 ---NKLTIDDEEYFENLGQLVAHYEA 555 Score = 53.2 bits (122), Expect = 4e-05 Identities = 30/77 (38%), Positives = 43/77 (55%), Gaps = 2/77 (2%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715 WFH TR +AE LL+ DG FLVR S G + + + +++H RVK E +L Sbjct: 479 WFHGSITRDEAEHLLQPRE-DGLFLVRESTNFPGDYTLCVCFQSKVEHYRVKYLENKLTI 537 Query: 716 IGTVKFESLIELVSYYE 732 FE+L +LV++YE Sbjct: 538 DDEEYFENLGQLVAHYE 554 >UniRef50_Q9UJU6 Cluster: Drebrin-like protein; n=47; Euteleostomi|Rep: Drebrin-like protein - Homo sapiens (Human) Length = 430 Score = 60.5 bits (140), Expect = 3e-07 Identities = 30/55 (54%), Positives = 36/55 (65%), Gaps = 2/55 (3%) Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH-WFPANYVLEIE 835 +ALYDY+A D E+SF +IT ++ DEGWWRG YG H FPANYV IE Sbjct: 377 RALYDYQAADDTEISFDPENLITGIEVIDEGWWRG-YGPDGHFGMFPANYVELIE 430 >UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila melanogaster (Fruit fly) Length = 1620 Score = 60.5 bits (140), Expect = 3e-07 Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 12/120 (10%) Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709 N E W+H +R AE LL + +G+FLVR SE G +IS R E + H R+ + Sbjct: 247 NSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRISE 305 Query: 710 --EGRLYTIGTVKFESLIELVSY----YENHPLYKKVKLWYPISEE---TVRRLVSEPDD 760 +G+++ KF +L ELV + +E H L L YP ++ TV L EPD+ Sbjct: 306 DPDGKVFVTQEAKFNTLAELVHHHSVPHEGHGLI--TPLLYPAPKQNKPTVFPLSPEPDE 363 Score = 48.8 bits (111), Expect = 9e-04 Identities = 38/121 (31%), Positives = 58/121 (47%), Gaps = 10/121 (8%) Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590 N + P + L W+HG ++ R AE LL + + G+FLVRES + G +S Sbjct: 241 NYVTPLNSLE-KHSWYHGPIS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 294 Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650 +G+V H RI E K ++ F++L L+ H+ S P + L P P+ N Sbjct: 295 EGRVYHYRI---SEDPDGKVFVTQEAKFNTLAELV-HHHSVPHEGHGLITPLLYPAPKQN 350 Query: 651 K 651 K Sbjct: 351 K 351 >UniRef50_UPI0000D5645D Cluster: PREDICTED: similar to CG17367-PB, isoform B; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG17367-PB, isoform B - Tribolium castaneum Length = 488 Score = 60.1 bits (139), Expect = 4e-07 Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 6/91 (6%) Query: 543 ECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLK 602 E WFHG L R EA +L+ G G FLVR+S T G++ L+F QG+ H R+ + Sbjct: 320 EFWFHGTLG--RSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFNFQGRAKHLRMTI- 376 Query: 603 QERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 ++G + + F S+Y ++ H+R P+ Sbjct: 377 NDQGQCR---VQHFWFQSIYEMLEHFRQQPI 404 Score = 44.4 bits (100), Expect = 0.019 Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%) Query: 640 ITLKEPVPQPNKHEGKEWFHAHCTRTQAEELLRKTNT--DGAFLVRPSEKEQGSFAISFR 697 I+++ + Q K E WFH R++A L+ G FLVR SE G F ++F Sbjct: 307 ISMETDIGQTLKKEF--WFHGTLGRSEATNLVLHDGARGHGLFLVRQSETRTGEFVLTFN 364 Query: 698 TEKEIKHCR--VKQEGRLYTIGTVKFESLIELVSYYENHPL 736 + KH R + +G+ + F+S+ E++ ++ P+ Sbjct: 365 FQGRAKHLRMTINDQGQC-RVQHFWFQSIYEMLEHFRQQPI 404 >UniRef50_Q804J4 Cluster: Phospholipase C gamma 1; n=6; Danio rerio|Rep: Phospholipase C gamma 1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 50 Score = 60.1 bits (139), Expect = 4e-07 Identities = 26/48 (54%), Positives = 37/48 (77%), Gaps = 1/48 (2%) Query: 71 DIRDVKEVRTGKSSKDFERWPEE-TKRLESSKCFTIYYGTEFKLRCAS 117 DIR++KE+RTG+ S+DFER+ E+ T R + + CF I YGTEF+L+ S Sbjct: 1 DIREIKEIRTGQKSRDFERYVEDVTTRPDQAHCFVILYGTEFRLKSLS 48 >UniRef50_Q5M8F8 Cluster: Cortactin; n=2; Xenopus|Rep: Cortactin - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 553 Score = 60.1 bits (139), Expect = 4e-07 Identities = 36/92 (39%), Positives = 45/92 (48%), Gaps = 8/92 (8%) Query: 747 SEETVRRLVSEPDDNTVYGT-PGYMDPTSFTSK------VTVKALYDYRARQDDELSFCK 799 +EE + PDD +Y P P S + ALYDY DDE+SF Sbjct: 455 NEEDYEAVPDLPDDEALYEELPKEESPILIASSKQGGSGICAVALYDYEGGGDDEISFQP 514 Query: 800 HAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 +IT++D DEGWW G G+R FPANYV Sbjct: 515 QELITDIDMLDEGWWCGTCEGRR-GLFPANYV 545 >UniRef50_O00851 Cluster: Unconventional myosin IB; n=2; Entamoeba histolytica|Rep: Unconventional myosin IB - Entamoeba histolytica Length = 1049 Score = 60.1 bits (139), Expect = 4e-07 Identities = 30/54 (55%), Positives = 36/54 (66%), Gaps = 2/54 (3%) Query: 781 VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 VKALY Y A D+ELSF IIT ++K DEGWW+G+ G + W P NYV EI Sbjct: 998 VKALYPYTAANDEELSFKVGDIITILEK-DEGWWKGELNG-QEGWIPNNYVKEI 1049 >UniRef50_A4R8V8 Cluster: Putative uncharacterized protein; n=2; Sordariomycetes|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 799 Score = 60.1 bits (139), Expect = 4e-07 Identities = 28/52 (53%), Positives = 35/52 (67%), Gaps = 1/52 (1%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T ALYDY A +D+ELSF + A + N++ PDE WW G + GK FPANYV Sbjct: 745 TATALYDYEAAEDNELSFPEGAKVMNLEFPDEDWWFGHFQGK-SGLFPANYV 795 Score = 45.6 bits (103), Expect = 0.008 Identities = 18/51 (35%), Positives = 27/51 (52%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 YDY A +D+E+ +T+++ DE WW G FP+NYV +E Sbjct: 650 YDYEAAEDNEIELVDGQYVTDIEMVDEDWWMGTNSRGERGLFPSNYVELVE 700 >UniRef50_UPI0000D558FE Cluster: PREDICTED: similar to CG10083-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG10083-PA - Tribolium castaneum Length = 442 Score = 59.7 bits (138), Expect = 5e-07 Identities = 27/56 (48%), Positives = 36/56 (64%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T + +ALYDY+A D E+SF IITN+D+ D+GWW+G + FPANYV Sbjct: 383 TPGLQARALYDYQAVDDTEISFDPGDIITNIDQVDKGWWQGLAPNGTYGLFPANYV 438 >UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens (Human) Length = 488 Score = 59.7 bits (138), Expect = 5e-07 Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Query: 649 PNKHEGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRV 707 P + W+ + +RTQA++LL N GAFL+RPSE G +++S R + ++ H RV Sbjct: 112 PETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYRV 171 Query: 708 KQ--EGRLYTIGTVKFESLIELVSYYE 732 +G LY F L EL++YY+ Sbjct: 172 SMAADGSLYLQKGRLFPGLEELLTYYK 198 Score = 40.3 bits (90), Expect = 0.31 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 4/79 (5%) Query: 553 NRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQERGVTKFYL 612 +R +A+ LL + + G FL+R S + +G Y LS Q KV H R+ + + + YL Sbjct: 126 SRTQAQQLLLSPPN-EPGAFLIRPSESSLGGYSLSVRAQAKVCHYRVSMAADGSL---YL 181 Query: 613 IDSMCFDSLYNLITHYRSH 631 F L L+T+Y+++ Sbjct: 182 QKGRLFPGLEELLTYYKAN 200 >UniRef50_Q17M42 Cluster: Putative uncharacterized protein; n=1; Aedes aegypti|Rep: Putative uncharacterized protein - Aedes aegypti (Yellowfever mosquito) Length = 393 Score = 59.3 bits (137), Expect = 6e-07 Identities = 28/76 (36%), Positives = 43/76 (56%) Query: 756 SEPDDNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWR 815 +EP + +D + + + +ALYDY+A + E+SF IIT++D+ DEGWW+ Sbjct: 315 AEPVVQEFFDPNATIDLSDEDNMIKARALYDYQAADESEISFDPGDIITHIDQIDEGWWQ 374 Query: 816 GDYGGKRHHWFPANYV 831 G + FPANYV Sbjct: 375 GLAPDGTYGLFPANYV 390 >UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1 - Spongilla lacustris (Freshwater sponge) Length = 505 Score = 59.3 bits (137), Expect = 6e-07 Identities = 32/96 (33%), Positives = 54/96 (56%), Gaps = 3/96 (3%) Query: 653 EGKEWFHAHCTRTQAEELLRKT-NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK--Q 709 + +EWF R +AE++L ++ N G+FL+R SE G F++S + + ++H RV+ + Sbjct: 118 DAEEWFLGKIKRVEAEKMLNQSFNQVGSFLIRDSETTPGDFSLSVKDQDRVRHYRVRRLE 177 Query: 710 EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYP 745 +G L+ F+ L ELV +Y+ KL YP Sbjct: 178 DGSLFVTRRSTFQILHELVDHYKIETDGLCCKLLYP 213 Score = 48.4 bits (110), Expect = 0.001 Identities = 32/88 (36%), Positives = 48/88 (54%), Gaps = 6/88 (6%) Query: 542 AECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKL 601 AE WF GK+ R EAE +L + G+FL+R+S T GD+ LS Q +V H R++ Sbjct: 119 AEEWFLGKI--KRVEAEKMLNQSFNQV-GSFLIRDSETTPGDFSLSVKDQDRVRHYRVR- 174 Query: 602 KQERGVTKFYLIDSMCFDSLYNLITHYR 629 + E G ++ F L+ L+ HY+ Sbjct: 175 RLEDG--SLFVTRRSTFQILHELVDHYK 200 Score = 37.9 bits (84), Expect = 1.7 Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 2/51 (3%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWW--RGDYGGKRHHWFPANYVLE 833 YDY +R DD+LSF K ++ + + WW R + + P+NYV E Sbjct: 63 YDYDSRTDDDLSFKKGDLMYIISTDEGDWWFARSKDTAGKEGYIPSNYVAE 113 >UniRef50_UPI00015B5756 Cluster: PREDICTED: similar to GA10060-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to GA10060-PA - Nasonia vitripennis Length = 542 Score = 58.8 bits (136), Expect = 8e-07 Identities = 30/71 (42%), Positives = 42/71 (59%), Gaps = 2/71 (2%) Query: 769 YMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPA 828 Y+DP + K +ALYDY+A D E++F IIT++D DEGWW+G + FPA Sbjct: 474 YLDPNNQGMKA--RALYDYQAADDTEITFDPGDIITHIDAIDEGWWQGLAPDGTYGLFPA 531 Query: 829 NYVLEIEVPHT 839 N+V I+ T Sbjct: 532 NHVEVIDYGST 542 >UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-oncogene tyrosine-protein kinase abl1; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to proto-oncogene tyrosine-protein kinase abl1 - Nasonia vitripennis Length = 1522 Score = 58.8 bits (136), Expect = 8e-07 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 6/116 (5%) Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ 709 N E W+H +R AE LL + +G+FLVR SE G +IS R E + H R+ + Sbjct: 168 NSLEKHSWYHGRISRNAAEYLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINE 226 Query: 710 --EGRLYTIGTVKFESLIELVSYYENHPLYKKVKLWYPI---SEETVRRLVSEPDD 760 +G++Y F +L ELV ++ +L YP ++ TV L EPD+ Sbjct: 227 DSDGKMYVTTESIFNTLAELVHHHSMLADGLITQLLYPAPKRNKPTVFPLSPEPDE 282 Score = 50.8 bits (116), Expect = 2e-04 Identities = 38/121 (31%), Positives = 59/121 (48%), Gaps = 12/121 (9%) Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590 N + P + L W+HG+++ R AE LL + + G+FLVRES + G +S Sbjct: 162 NYVTPVNSLE-KHSWYHGRIS--RNAAEYLLSSGIN---GSFLVRESESSPGQRSISLRY 215 Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650 +G+V H RI E K Y+ F++L L+ H H + + + L P P+ N Sbjct: 216 EGRVYHYRI---NEDSDGKMYVTTESIFNTLAELVHH---HSMLADGLITQLLYPAPKRN 269 Query: 651 K 651 K Sbjct: 270 K 270 >UniRef50_UPI00006A0536 Cluster: Nck1-prov protein.; n=1; Xenopus tropicalis|Rep: Nck1-prov protein. - Xenopus tropicalis Length = 345 Score = 58.8 bits (136), Expect = 8e-07 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVL-EIEVPHTPDVT 843 + Y A +DDELS K + ++K +GWWRG Y G R WFP+NYV E + P V Sbjct: 115 FTYTAERDDELSLVKGTKVIVMEKCSDGWWRGSYNG-RVGWFPSNYVTEENDSPSGDQVG 173 Query: 844 SGLENESAALGSLQKG 859 + E +A + +L G Sbjct: 174 TLTEKLAAVVNNLNNG 189 Score = 37.5 bits (83), Expect = 2.2 Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T +V V A +DY A+QD EL K+ + +D + WWR + + P+NYV Sbjct: 3 TEEVIVVAKFDYVAQQDQELDIKKNERLWLLD-DSKSWWRVRNSMNKTGFVPSNYV 57 Score = 36.3 bits (80), Expect = 5.1 Identities = 15/43 (34%), Positives = 23/43 (53%) Query: 654 GKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISF 696 G +W++ TR QAE L + +G FL+R SE + S+ Sbjct: 279 GNQWYYGKVTRHQAEMALNERGNEGDFLIRDSESSVSNLGHSY 321 >UniRef50_O96459 Cluster: SRC8; n=2; Strongylocentrotus purpuratus|Rep: SRC8 - Strongylocentrotus purpuratus (Purple sea urchin) Length = 587 Score = 58.8 bits (136), Expect = 8e-07 Identities = 28/50 (56%), Positives = 36/50 (72%), Gaps = 1/50 (2%) Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 KALYDY+A +DEL+F + IIT+V+ D+GWW+G GK FPANYV Sbjct: 533 KALYDYQATAEDELTFDPNEIITHVETIDDGWWKGVCRGK-VGLFPANYV 581 >UniRef50_Q4S1M8 Cluster: Chromosome 6 SCAF14768, whole genome shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 6 SCAF14768, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 634 Score = 58.4 bits (135), Expect = 1e-06 Identities = 25/51 (49%), Positives = 35/51 (68%), Gaps = 1/51 (1%) Query: 785 YDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEIE 835 +DY A+QDDELS II N+ + D GWW G+ GG+R +FP N+V E++ Sbjct: 7 FDYEAQQDDELSLTVGDIIVNIRRDDGGWWEGELGGRR-GFFPDNFVREMK 56 Score = 45.2 bits (102), Expect = 0.011 Identities = 26/58 (44%), Positives = 34/58 (58%), Gaps = 5/58 (8%) Query: 782 KALYDYRARQDDELSFCKHAIITNVDKP--DEGWWRGDYGGKRHHWFPANYV--LEIE 835 K L+ Y A+ +DELS + II + K D GWW G+ GG R FP N+V LE+E Sbjct: 274 KVLFPYEAQNEDELSIKEGDIINIITKDCADAGWWMGETGG-RQGVFPDNFVKLLELE 330 Score = 39.5 bits (88), Expect = 0.54 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%) Query: 782 KALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 KA + Y + +DEL +I + + +EGWW G GK FP+N+ EI Sbjct: 110 KAAFSYLPQHEDELELKAGDVIEILAEVEEGWWEGLLNGKT-GMFPSNFTKEI 161 >UniRef50_Q17DJ2 Cluster: Signal transduction protein lnk-realted; n=2; Endopterygota|Rep: Signal transduction protein lnk-realted - Aedes aegypti (Yellowfever mosquito) Length = 564 Score = 58.4 bits (135), Expect = 1e-06 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 6/89 (6%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG LA R EA L+ + G FLVR+S T G++ L+F QGK H R+ L + Sbjct: 419 WFHGTLA--RSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTL-ND 475 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 G + + + F S+ ++ H+R HP+ Sbjct: 476 LGQCR---VQHLWFPSITEMLEHFRQHPI 501 Score = 48.8 bits (111), Expect = 9e-04 Identities = 24/83 (28%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Query: 657 WFHAHCTRTQAEELLRKT--NTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRL 713 WFH R++A +L+ ++ G FLVR SE +G F ++F + + KH R+ + Sbjct: 419 WFHGTLARSEAAQLVLHNGLSSHGVFLVRQSETRKGEFVLTFNFQGKAKHLRMTLNDLGQ 478 Query: 714 YTIGTVKFESLIELVSYYENHPL 736 + + F S+ E++ ++ HP+ Sbjct: 479 CRVQHLWFPSITEMLEHFRQHPI 501 >UniRef50_Q12897 Cluster: Phospholipase C-like; n=16; Euteleostomi|Rep: Phospholipase C-like - Homo sapiens (Human) Length = 59 Score = 58.4 bits (135), Expect = 1e-06 Identities = 25/54 (46%), Positives = 37/54 (68%), Gaps = 1/54 (1%) Query: 701 EIKHCRVKQEGRLYTIGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRR 753 ++KHCR+ ++ G FESL+ELVSYYE H LY+K++L YP++ E + R Sbjct: 4 KVKHCRINRDAGTLCWGPPPIFESLVELVSYYEKHSLYRKMRLCYPVTPELLER 57 >UniRef50_Q5KHY4 Cluster: Putative uncharacterized protein; n=1; Filobasidiella neoformans|Rep: Putative uncharacterized protein - Cryptococcus neoformans (Filobasidiella neoformans) Length = 693 Score = 58.4 bits (135), Expect = 1e-06 Identities = 34/98 (34%), Positives = 47/98 (47%), Gaps = 2/98 (2%) Query: 767 PGYMDPTSFTSKV--TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHH 824 P ++P S S K LYDY A +D+ELS + IIT +++ DEGWW G + Sbjct: 510 PRTIEPASEPSPAGKRAKVLYDYDAAEDNELSLREDDIITQIEQLDEGWWSGTNADGQSG 569 Query: 825 WFPANYVLEIEVPHTPDVTSGLENESAALGSLQKGVLD 862 FPANY IE P + E A + ++D Sbjct: 570 LFPANYCELIEDDSAPAANPQYQVEPEAELETEPTIID 607 Score = 50.0 bits (114), Expect = 4e-04 Identities = 24/60 (40%), Positives = 36/60 (60%), Gaps = 1/60 (1%) Query: 773 TSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVL 832 +S+ + A YDY A +D+ELSF + IT+++K D WW+G G + FPA YV+ Sbjct: 626 SSYAKDTVMIAAYDYDASEDNELSFKEGDQITDIEKIDPDWWQGKCNG-QEGLFPAAYVV 684 >UniRef50_P19706 Cluster: Myosin heavy chain IB; n=5; Eukaryota|Rep: Myosin heavy chain IB - Acanthamoeba castellanii (Amoeba) Length = 1147 Score = 58.4 bits (135), Expect = 1e-06 Identities = 29/58 (50%), Positives = 35/58 (60%), Gaps = 1/58 (1%) Query: 777 SKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI 834 +K VKALYDY A+ DEL+F + I K GWW G+ GKR W PANYV +I Sbjct: 1091 AKPQVKALYDYDAQTGDELTFKEGDTIIVHQKDPAGWWEGELNGKR-GWVPANYVQDI 1147 >UniRef50_Q6C2N2 Cluster: Class E vacuolar protein-sorting machinery protein HSE1; n=1; Yarrowia lipolytica|Rep: Class E vacuolar protein-sorting machinery protein HSE1 - Yarrowia lipolytica (Candida lipolytica) Length = 685 Score = 58.4 bits (135), Expect = 1e-06 Identities = 35/90 (38%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Query: 761 NTVYGTPGYMDPTSFTSKVT-VKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819 NT P DPT + V+ VKALYD A + ELSF K IIT ++ WWRG Sbjct: 234 NTNNNAPAVEDPTPTVATVSRVKALYDLNATEPGELSFRKGDIITVLESVFRDWWRGSLR 293 Query: 820 GKRHHWFPANYVLEIEVPHTPDVTSGLENE 849 G + FP NYV+ I P ++ + E Sbjct: 294 G-QVGIFPLNYVMPIAEPTPAEIEKEAQEE 322 >UniRef50_UPI0000ECA6D9 Cluster: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein).; n=1; Gallus gallus|Rep: SH2B adapter protein 3 (Lymphocyte-specific adapter protein Lnk) (Signal transduction protein Lnk) (Lymphocyte adapter protein). - Gallus gallus Length = 506 Score = 58.0 bits (134), Expect = 1e-06 Identities = 34/100 (34%), Positives = 55/100 (55%), Gaps = 7/100 (7%) Query: 535 PQDELHFAEC-WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGK 593 P+ E + C WFHG ++ R +A L++ G G FLVR+S T G+Y L+F QG+ Sbjct: 377 PKMEQFLSSCPWFHGPIS--RVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGR 434 Query: 594 VNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPL 633 H R+ L ERG + + + F S+ ++ H+ +P+ Sbjct: 435 AKHLRLSL-TERGQCR---VQHLRFSSITEMLHHFHRYPI 470 Score = 48.4 bits (110), Expect = 0.001 Identities = 23/83 (27%), Positives = 45/83 (54%), Gaps = 3/83 (3%) Query: 657 WFHAHCTRTQAEELLRKTNTDG--AFLVRPSEKEQGSFAISFRTEKEIKHCRVK-QEGRL 713 WFH +R +A +L++ +G FLVR SE +G + ++F + KH R+ E Sbjct: 388 WFHGPISRVKAAQLVQLGGLEGHGVFLVRQSETRRGEYVLTFNFQGRAKHLRLSLTERGQ 447 Query: 714 YTIGTVKFESLIELVSYYENHPL 736 + ++F S+ E++ ++ +P+ Sbjct: 448 CRVQHLRFSSITEMLHHFHRYPI 470 >UniRef50_A0JMM6 Cluster: Zgc:154014; n=11; Eumetazoa|Rep: Zgc:154014 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 550 Score = 58.0 bits (134), Expect = 1e-06 Identities = 25/52 (48%), Positives = 34/52 (65%), Gaps = 1/52 (1%) Query: 780 TVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 T +A+YDY+ DE+SF IITN++ DEGWW+G G R FPA++V Sbjct: 497 TARAIYDYQGEDSDEISFMPDDIITNIEMVDEGWWKGMCNG-RTGLFPASFV 547 >UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia fluviatilis|Rep: Protein tyrosine kinase - Ephydatia fluviatilis Length = 485 Score = 58.0 bits (134), Expect = 1e-06 Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 11/108 (10%) Query: 545 WFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWRQGKVNHCRIKLKQE 604 WFHG+++ R++AE LL + G FLVRES + GDY L G+V + R++ + E Sbjct: 109 WFHGRIS--REDAEKLLTPPKN---GRFLVRESQNYPGDYTLCVSYDGRVENYRVR-RNE 162 Query: 605 RGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPNKH 652 +G+ + D FD+L L+ HY+ + LK PV + +H Sbjct: 163 KGLVT--VDDDEYFDNLIKLVEHYQK---EADGLCTRLKAPVDKEGQH 205 Score = 48.8 bits (111), Expect = 9e-04 Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 3/106 (2%) Query: 657 WFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVKQ-EGRLYT 715 WFH +R AE+LL +G FLVR S+ G + + + +++ RV++ E L T Sbjct: 109 WFHGRISREDAEKLLTPPK-NGRFLVRESQNYPGDYTLCVSYDGRVENYRVRRNEKGLVT 167 Query: 716 IGTVK-FESLIELVSYYENHPLYKKVKLWYPISEETVRRLVSEPDD 760 + + F++LI+LV +Y+ +L P+ +E V + +D Sbjct: 168 VDDDEYFDNLIKLVEHYQKEADGLCTRLKAPVDKEGQHLFVVDVND 213 >UniRef50_UPI0000E7F989 Cluster: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148); n=1; Gallus gallus|Rep: PREDICTED: similar to 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1 (Phosphoinositide phospholipase C) (PLC-gamma-1) (Phospholipase C-gamma-1) (PLC-II) (PLC-148) - Gallus gallus Length = 131 Score = 57.6 bits (133), Expect = 2e-06 Identities = 34/73 (46%), Positives = 42/73 (57%), Gaps = 6/73 (8%) Query: 538 ELHFAECWFHGKLAGNR---QEAEDLLRAHA-HLGD--GTFLVRESVTFVGDYCLSFWRQ 591 ELH A+ WFHGKL R A+ LL + +G G+FLVRES FVGD+ LS W Sbjct: 50 ELHLAQDWFHGKLGAGRGGWHIAKWLLTEYCTEMGPPCGSFLVRESEIFVGDFVLSIWCD 109 Query: 592 GKVNHCRIKLKQE 604 KV H I +Q+ Sbjct: 110 EKVQHFHIHWQQD 122 >UniRef50_A2RQD7 Cluster: Bcr-abl1 e19a2 chimeric protein; n=2; Homo sapiens|Rep: Bcr-abl1 e19a2 chimeric protein - Homo sapiens (Human) Length = 498 Score = 57.6 bits (133), Expect = 2e-06 Identities = 31/84 (36%), Positives = 45/84 (53%), Gaps = 3/84 (3%) Query: 650 NKHEGKEWFHAHCTRTQAEELLRKTNTDGAFLVRPSEKEQGSFAISFRTEKEIKHCRVK- 708 N E W+H +R AE LL + +G+FLVR SE G +IS R E + H R+ Sbjct: 372 NSLEKHSWYHGPVSRNAAEHLL-SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 430 Query: 709 -QEGRLYTIGTVKFESLIELVSYY 731 +G+LY +F +L ELV ++ Sbjct: 431 ASDGKLYVSSESRFNTLAELVHHH 454 Score = 50.8 bits (116), Expect = 2e-04 Identities = 39/121 (32%), Positives = 58/121 (47%), Gaps = 12/121 (9%) Query: 531 NAIVPQDELHFAECWFHGKLAGNRQEAEDLLRAHAHLGDGTFLVRESVTFVGDYCLSFWR 590 N I P + L W+HG ++ R AE LL + + G+FLVRES + G +S Sbjct: 366 NYITPVNSLE-KHSWYHGPVS--RNAAEHLLSSGIN---GSFLVRESESSPGQRSISLRY 419 Query: 591 QGKVNHCRIKLKQERGVTKFYLIDSMCFDSLYNLITHYRSHPLRSQEFLITLKEPVPQPN 650 +G+V H RI + K Y+ F++L L+ H H + + TL P P+ N Sbjct: 420 EGRVYHYRINTASD---GKLYVSSESRFNTLAELVHH---HSTVADGLITTLHYPAPKRN 473 Query: 651 K 651 K Sbjct: 474 K 474 >UniRef50_Q6CEP4 Cluster: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica; n=1; Yarrowia lipolytica|Rep: Yarrowia lipolytica chromosome B of strain CLIB122 of Yarrowia lipolytica - Yarrowia lipolytica (Candida lipolytica) Length = 837 Score = 57.6 bits (133), Expect = 2e-06 Identities = 26/49 (53%), Positives = 34/49 (69%), Gaps = 1/49 (2%) Query: 783 ALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV 831 ALYDY A +D+ELSF IIT+++ DE WW G GKR + FP+N+V Sbjct: 786 ALYDYDAAEDNELSFAADDIITDIEFIDEDWWTGSLNGKR-NLFPSNFV 833 Score = 44.8 bits (101), Expect = 0.014 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 2/68 (2%) Query: 776 TSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYV--LE 833 +SK + YDY ++ E+ + I+T+++ DE WW G FP+NYV + Sbjct: 696 SSKPSATVEYDYTKDEEGEIDLVEDEIVTDIEFLDENWWSGTNSKGESGLFPSNYVRLKD 755 Query: 834 IEVPHTPD 841 VP PD Sbjct: 756 GAVPTIPD 763 >UniRef50_Q15052 Cluster: Rho guanine nucleotide exchange factor 6; n=14; Tetrapoda|Rep: Rho guanine nucleotide exchange factor 6 - Homo sapiens (Human) Length = 776 Score = 57.6 bits (133), Expect = 2e-06 Identities = 30/73 (41%), Positives = 40/73 (54%), Gaps = 4/73 (5%) Query: 778 KVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYGGKRHHWFPANYVLEI--- 834 ++ VKA ++++ +DELS CK II + GWW G G R WFP+NYV EI Sbjct: 162 QLIVKARFNFKQTNEDELSVCKGDIIYVTRVEEGGWWEGTLNG-RTGWFPSNYVREIKSS 220 Query: 835 EVPHTPDVTSGLE 847 E P +P G E Sbjct: 221 ERPLSPKAVKGFE 233 >UniRef50_Q6GM14 Cluster: MGC84047 protein; n=9; Tetrapoda|Rep: MGC84047 protein - Xenopus laevis (African clawed frog) Length = 376 Score = 57.2 bits (132), Expect = 3e-06 Identities = 28/76 (36%), Positives = 40/76 (52%) Query: 760 DNTVYGTPGYMDPTSFTSKVTVKALYDYRARQDDELSFCKHAIITNVDKPDEGWWRGDYG 819 ++T P Y + S + +ALYDY+A D E+SF +I ++ D+GWWRG Sbjct: 301 EDTPQEDPVYETGVAEDSGMCARALYDYQAADDTEISFDPDDVIIQIEMIDDGWWRGVAP 360 Query: 820 GKRHHWFPANYVLEIE 835 FPANYV +E Sbjct: 361 SGHFGMFPANYVELLE 376 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.320 0.136 0.416 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,337,361,673 Number of Sequences: 1657284 Number of extensions: 57110858 Number of successful extensions: 125952 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 559 Number of HSP's successfully gapped in prelim test: 566 Number of HSP's that attempted gapping in prelim test: 123409 Number of HSP's gapped (non-prelim): 2262 length of query: 1201 length of database: 575,637,011 effective HSP length: 109 effective length of query: 1092 effective length of database: 394,993,055 effective search space: 431332416060 effective search space used: 431332416060 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.8 bits) S2: 78 (35.5 bits)
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