Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000591-TA|BGIBMGA000591-PA|IPR003961|Fibronectin, type
III, IPR013098|Immunoglobulin I-set, IPR008957|Fibronectin, type
III-like fold, IPR007110|Immunoglobulin-like, IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2
(1081 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 187 2e-46
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 187 2e-46
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 187 2e-46
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 187 2e-46
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 154 2e-36
X64698-1|CAA45939.1| 1100|Homo sapiens titin protein. 138 1e-31
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 123 4e-27
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 122 5e-27
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 122 9e-27
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 122 9e-27
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 122 9e-27
U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding pr... 121 1e-26
AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein ... 121 1e-26
Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C ... 120 4e-26
X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding pr... 120 4e-26
X64699-1|CAA45940.1| 531|Homo sapiens titin protein. 108 9e-23
AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens ... 105 1e-21
BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein ... 104 2e-21
AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein ... 104 2e-21
L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin bi... 101 1e-20
BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein ... 101 1e-20
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 99 4e-20
BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein ... 100 6e-20
BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein ... 100 6e-20
AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein... 100 6e-20
U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H ... 99 7e-20
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 99 1e-19
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 96 7e-19
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 94 2e-18
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 91 1e-17
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 91 1e-17
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 91 1e-17
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 91 2e-17
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 91 2e-17
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 91 2e-17
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 91 2e-17
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 89 6e-17
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 89 6e-17
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 89 8e-17
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 89 8e-17
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 88 1e-16
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 88 1e-16
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 88 1e-16
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 88 1e-16
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 88 1e-16
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 88 1e-16
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 88 1e-16
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 86 7e-16
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 86 7e-16
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 85 1e-15
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 84 2e-15
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 84 3e-15
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 84 3e-15
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 83 4e-15
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 83 5e-15
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 83 5e-15
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 83 5e-15
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 83 7e-15
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 83 7e-15
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 83 7e-15
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 82 1e-14
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 82 1e-14
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 82 1e-14
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 80 5e-14
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 80 5e-14
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 80 5e-14
AJ314898-1|CAC85746.1| 646|Homo sapiens obscurin protein. 80 5e-14
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 80 5e-14
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 79 6e-14
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 79 6e-14
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 79 6e-14
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 78 2e-13
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 78 2e-13
BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein. 78 2e-13
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 78 2e-13
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 78 2e-13
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 78 2e-13
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 78 2e-13
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 77 3e-13
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 77 3e-13
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 77 5e-13
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 77 5e-13
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 77 5e-13
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 77 5e-13
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 77 5e-13
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 77 5e-13
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 77 5e-13
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 76 6e-13
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 76 8e-13
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 76 8e-13
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 76 8e-13
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 76 8e-13
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 76 8e-13
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 76 8e-13
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 76 8e-13
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 76 8e-13
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 76 8e-13
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 75 1e-12
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 75 1e-12
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 75 1e-12
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 75 1e-12
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 75 1e-12
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 75 1e-12
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 75 1e-12
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 75 1e-12
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 75 1e-12
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 75 1e-12
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 75 1e-12
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 75 1e-12
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 74 2e-12
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 74 3e-12
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 74 3e-12
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 74 3e-12
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 73 7e-12
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 72 1e-11
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 72 1e-11
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 72 1e-11
AK129856-1|BAC85243.1| 295|Homo sapiens protein ( Homo sapiens ... 72 1e-11
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 72 1e-11
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 72 1e-11
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 72 1e-11
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 72 1e-11
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 72 1e-11
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 72 1e-11
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 70 4e-11
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 70 5e-11
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 70 5e-11
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 70 5e-11
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 70 5e-11
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 70 5e-11
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 70 5e-11
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 70 5e-11
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 70 5e-11
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 70 5e-11
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 70 5e-11
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 70 5e-11
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 70 5e-11
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 69 7e-11
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 69 9e-11
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 69 1e-10
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 69 1e-10
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 68 2e-10
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 68 2e-10
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 68 2e-10
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 68 2e-10
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 67 3e-10
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 67 4e-10
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 67 4e-10
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 67 4e-10
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 67 4e-10
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 67 4e-10
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 67 4e-10
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 66 5e-10
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 66 5e-10
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 66 5e-10
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 66 5e-10
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 66 5e-10
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 66 6e-10
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 65 1e-09
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 65 1e-09
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 65 1e-09
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 65 1e-09
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 65 1e-09
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 65 1e-09
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 65 1e-09
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 65 1e-09
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 65 1e-09
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 65 1e-09
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 65 1e-09
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 65 1e-09
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 65 1e-09
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 64 2e-09
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 64 2e-09
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 64 2e-09
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 64 2e-09
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 64 2e-09
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 64 2e-09
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 64 3e-09
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 64 3e-09
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 64 3e-09
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 64 3e-09
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 64 3e-09
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 64 3e-09
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 64 3e-09
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 64 3e-09
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 64 3e-09
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 64 3e-09
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 64 3e-09
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 64 3e-09
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 64 3e-09
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 64 3e-09
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 63 5e-09
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 63 5e-09
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 63 6e-09
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 62 8e-09
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 62 8e-09
BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein. 62 8e-09
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 62 8e-09
AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein pr... 62 8e-09
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 62 8e-09
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 62 8e-09
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 62 8e-09
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 62 8e-09
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 62 1e-08
BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein. 62 1e-08
AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AK125972-1|BAC86370.1| 365|Homo sapiens protein ( Homo sapiens ... 62 1e-08
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 61 2e-08
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 61 2e-08
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 61 2e-08
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 61 2e-08
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 60 3e-08
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 60 3e-08
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 59 7e-08
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 59 1e-07
X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein. 59 1e-07
BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa prot... 59 1e-07
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 59 1e-07
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 59 1e-07
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 59 1e-07
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 59 1e-07
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 59 1e-07
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 59 1e-07
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 59 1e-07
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 59 1e-07
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 59 1e-07
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 59 1e-07
AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member... 59 1e-07
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 59 1e-07
AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein. 59 1e-07
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 59 1e-07
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 59 1e-07
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 59 1e-07
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 59 1e-07
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 59 1e-07
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 58 1e-07
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 58 1e-07
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 58 1e-07
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 58 1e-07
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 58 1e-07
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 58 1e-07
BC063822-1|AAH63822.1| 1009|Homo sapiens EGF-like, fibronectin t... 58 2e-07
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 58 2e-07
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AK096474-1|BAC04800.1| 403|Homo sapiens protein ( Homo sapiens ... 58 2e-07
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 58 2e-07
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 58 2e-07
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr... 58 2e-07
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 58 2e-07
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 58 2e-07
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 58 2e-07
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 58 2e-07
AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens ... 58 2e-07
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 57 3e-07
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 57 4e-07
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 57 4e-07
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 56 5e-07
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 56 5e-07
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 56 5e-07
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 56 5e-07
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 56 5e-07
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 56 5e-07
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 56 5e-07
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 56 5e-07
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 56 5e-07
X69089-1|CAA48832.1| 1465|Homo sapiens 165kD protein protein. 56 9e-07
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 56 9e-07
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 56 9e-07
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 56 9e-07
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 56 9e-07
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 56 9e-07
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 55 1e-06
CR457157-1|CAG33438.1| 442|Homo sapiens IGSF4 protein. 55 1e-06
AY358334-1|AAQ88700.1| 440|Homo sapiens IGSF4 protein. 55 1e-06
AF132811-1|AAF69029.1| 442|Homo sapiens nectin-like protein 2 p... 55 1e-06
AB017563-1|BAA75822.1| 442|Homo sapiens IGSF4 protein. 55 1e-06
BC052969-1|AAH52969.1| 1465|Homo sapiens myomesin (M-protein) 2,... 55 2e-06
BC039297-1|AAH39297.1| 1204|Homo sapiens fibronectin type III do... 55 2e-06
BC033635-1|AAH33635.1| 753|Homo sapiens FNDC3B protein protein. 55 2e-06
AY358146-1|AAQ88513.1| 847|Homo sapiens YVTM2421 protein. 55 2e-06
AK223599-1|BAD97319.1| 1204|Homo sapiens factor for adipocyte di... 55 2e-06
AK075220-1|BAC11480.1| 760|Homo sapiens protein ( Homo sapiens ... 55 2e-06
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 54 2e-06
BC029496-1|AAH29496.1| 128|Homo sapiens PTPRS protein protein. 54 2e-06
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 54 2e-06
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 54 3e-06
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 54 3e-06
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 54 3e-06
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 54 3e-06
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 54 3e-06
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 54 3e-06
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 54 3e-06
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 54 3e-06
AB098597-1|BAC53727.1| 1204|Homo sapiens FAD104 protein. 54 3e-06
AB209396-1|BAD92633.1| 675|Homo sapiens surface glycoprotein, I... 54 4e-06
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein. 53 5e-06
AC005790-1|AAC62832.1| 126|Homo sapiens PTP sigma [AA 1- 126] p... 53 5e-06
AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein. 53 5e-06
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 53 5e-06
AK074556-1|BAC11057.1| 789|Homo sapiens protein ( Homo sapiens ... 53 6e-06
AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein. 53 6e-06
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 52 8e-06
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 52 8e-06
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 52 8e-06
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 52 8e-06
BC132812-1|AAI32813.1| 1198|Homo sapiens FNDC3A protein protein. 52 1e-05
BC070072-1|AAH70072.1| 853|Homo sapiens FNDC3A protein protein. 52 1e-05
BC060816-1|AAH60816.1| 853|Homo sapiens FNDC3A protein protein. 52 1e-05
AL137000-1|CAI39726.2| 1142|Homo sapiens fibronectin type III do... 52 1e-05
AJ749707-1|CAG44603.1| 1134|Homo sapiens human gene expressed in... 52 1e-05
AJ749706-1|CAG44602.1| 1198|Homo sapiens human gene expressed in... 52 1e-05
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 52 1e-05
AB023187-1|BAA76814.2| 1151|Homo sapiens KIAA0970 protein protein. 52 1e-05
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 51 2e-05
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 51 3e-05
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 51 3e-05
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 51 3e-05
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 51 3e-05
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 51 3e-05
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 51 3e-05
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 51 3e-05
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 50 3e-05
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 50 3e-05
AK075502-1|BAC11657.1| 443|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 50 3e-05
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 50 4e-05
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 50 6e-05
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 50 6e-05
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 50 6e-05
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 50 6e-05
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 50 6e-05
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 50 6e-05
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 50 6e-05
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 50 6e-05
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 50 6e-05
AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion mo... 49 1e-04
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 48 1e-04
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 48 1e-04
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 48 1e-04
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 48 1e-04
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 48 2e-04
BC125103-1|AAI25104.1| 414|Homo sapiens CADM1 protein protein. 48 2e-04
BC125102-1|AAI25103.1| 415|Homo sapiens CADM1 protein protein. 48 2e-04
BC047021-1|AAH47021.1| 387|Homo sapiens CADM1 protein protein. 48 2e-04
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 48 2e-04
AB094146-1|BAC66178.1| 333|Homo sapiens secretory isoform of TS... 48 2e-04
BC111748-1|AAI11749.1| 1007|Homo sapiens roundabout homolog 4, m... 48 2e-04
BC111562-1|AAI11563.1| 1007|Homo sapiens roundabout homolog 4, m... 48 2e-04
BC039602-1|AAH39602.1| 1007|Homo sapiens roundabout homolog 4, m... 48 2e-04
AY358083-1|AAQ88450.1| 1004|Homo sapiens magic roundabout protein. 48 2e-04
AJ314903-1|CAC85750.1| 542|Homo sapiens obscurin protein. 48 2e-04
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 48 2e-04
AF361473-1|AAL31867.1| 1007|Homo sapiens magic roundabout protein. 48 2e-04
Y08110-1|CAA69325.1| 2214|Homo sapiens mosaic protein LR11 protein. 47 3e-04
U60975-1|AAC50891.2| 2214|Homo sapiens gp250 precursor protein. 47 3e-04
BC043916-1|AAH43916.1| 767|Homo sapiens OBSCN protein protein. 47 3e-04
AL590103-6|CAI12129.1| 188|Homo sapiens heparan sulfate proteog... 47 3e-04
AL353593-1|CAI19283.1| 709|Homo sapiens obscurin, cytoskeletal ... 47 3e-04
AJ314904-1|CAC85751.1| 658|Homo sapiens obscurin protein. 47 3e-04
BC014671-1|AAH14671.1| 331|Homo sapiens MYOM3 protein protein. 46 6e-04
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 46 6e-04
AL591178-2|CAH72089.1| 330|Homo sapiens myomesin family, member... 46 6e-04
AJ314900-1|CAC85747.1| 551|Homo sapiens obscurin protein. 46 6e-04
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 46 7e-04
AY481573-1|AAS47698.1| 5202|Homo sapiens Usher syndrome 2A isofo... 46 0.001
AL513305-1|CAH73621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 0.001
AL445650-4|CAH70621.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 0.001
AL358858-2|CAH71588.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 0.001
AL358452-1|CAI19189.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 0.001
AL139259-1|CAI23041.1| 5202|Homo sapiens Usher syndrome 2A (auto... 46 0.001
AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens ... 46 0.001
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 46 0.001
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 45 0.001
X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphat... 45 0.001
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 45 0.001
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 45 0.001
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 45 0.001
DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein. 45 0.001
BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein. 45 0.001
BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein. 45 0.001
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 45 0.001
AK023854-1|BAB14704.1| 442|Homo sapiens .117). protein. 45 0.001
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 45 0.001
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 45 0.002
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 45 0.002
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 45 0.002
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 45 0.002
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 45 0.002
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 45 0.002
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 45 0.002
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 45 0.002
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 187 bits (456), Expect = 2e-46
Identities = 118/393 (30%), Positives = 177/393 (45%), Gaps = 10/393 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PGKP I + D + + W P DGGA +R Y +E +WI +
Sbjct: 24327 KPGAPGKPTITAVTKD----SCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI 24382
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ L +Y+FRV N G S +SE+S+ +T SD Q P F + L ++
Sbjct: 24383 RETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPH-FKEELRNLN 24441
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--LLFHQILPSDEG 253
+G P P + W++ EI + + L+ + D
Sbjct: 24442 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 24501
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLYEIN-ETIFLKTTIVGKPTPT 311
+ ATN+GG A L +E K+ P+ E G ++ + E + +K GKP P
Sbjct: 24502 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 24561
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKI-HSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W+ I + ++ +T F+ L + +R D G Y + AKN G D + V
Sbjct: 24562 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
PDPPR V V+ SV L W PA DGG K+ NYIVE T WL+ +R+T
Sbjct: 24622 ADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR 24681
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
T+ +L + Y+FR+ AE+ +G+S PS S P
Sbjct: 24682 YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 24714
Score = 180 bits (438), Expect = 2e-44
Identities = 110/395 (27%), Positives = 186/395 (47%), Gaps = 10/395 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P+ PG+ +I+ I D ++TL+W DGG + GY VE + G + W ++ +
Sbjct: 23933 KPSQPGELEILSISKD----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 23988
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ + GL +Y+FRV A N+ G S + +++ + S E P K ++DVT
Sbjct: 23989 KDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEMKDVT 24046
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P I W++ E+ SR+ +++D T L DEG
Sbjct: 24047 TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C ATN G T ++L L+A P+ ++ + T+ L +G+P P + W
Sbjct: 24107 TCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF 24166
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKR-SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
H + + I I T ++ L + + +R + G+Y++Q N+ G A V + P
Sbjct: 24167 HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKP 24226
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVE--YYRTGWNVWLKAITSRKTNV 431
D P + + + S + W+PPADDGG + NY+VE + G L + T
Sbjct: 24227 DKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTC 24286
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ +L E + Y FR+ A++ +G+S P SS V I
Sbjct: 24287 RIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 24321
Score = 154 bits (373), Expect = 2e-36
Identities = 112/400 (28%), Positives = 186/400 (46%), Gaps = 23/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PPGKP +++D NA T+ W DGG+P+ GY +E R + +W+R +
Sbjct: 11207 PSPPGKP----VVTDITENAATVSWTLPKSDGGSPITGYYME-RREVTGKWVRVNKTPIA 11261
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ +TGL + Y+FRV A N G S S SD + PP+ K L+D +
Sbjct: 11262 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPK-LKDKSR 11320
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGE 254
D V G SP + + + + +++ I DE F ++ +E
Sbjct: 11321 ETADLVWTKPLSDG-GSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYR 11379
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE------DGLLYEINETIFLKTTIVGKP 308
+ A N G + A + +P + E D + + +TI + + G+P
Sbjct: 11380 FRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRP 11439
Query: 309 TPTIEWRHDGHPIITDDRIE-ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P I W +G ++ + R++ I P+ L+I A R+D G+Y I AKN G + +
Sbjct: 11440 EPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRADHGKYIISAKNSSGHAQGSAI 11498
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR---TGWNVWLKAI 424
V V P P +N+ VT ++ T+ WE P D+GG ++ N+IVEY + GW++ +
Sbjct: 11499 VNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDV 11558
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T R +L+ +EY FR+ AE+ G+ +P+
Sbjct: 11559 TKRLIKA---NLLANNEYYFRVCAENKVGVGPTIETKTPI 11595
Score = 149 bits (361), Expect = 5e-35
Identities = 116/411 (28%), Positives = 172/411 (41%), Gaps = 21/411 (5%)
Query: 58 ASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQV 117
A + A + +K + P P G P + L+++ + L W DGG+P+ Y +
Sbjct: 10100 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNE---SCKLTWFSPEDDGGSPITNYVI 10156
Query: 118 ECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS 177
E W + R + GL Y FR+AA N +G + E S+ L +
Sbjct: 10157 EKRESDRRAWTPVTYTVT-RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI-- 10213
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIP----SPTIAWFKDDYEIFSSRRTAI 233
+EP +R ED+ E K +T++ S I + + I + + +
Sbjct: 10214 ----REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKV 10269
Query: 234 TTDESTS-VLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQYED 288
T D S + D E + +A N G TK C + + D
Sbjct: 10270 TNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD 10329
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L + E L GKP P + W D ++ DDR I TP L+ AKRSD
Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGN 407
G+Y + +N G V V P PP VS + + W+PP DDGG K+ N
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNVVDHPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITN 10449
Query: 408 YIVEYYRTGWNVWLKAIT-SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
YI+E G +VW+ + S KT + L+EG +Y FRI AE+ YG+S P
Sbjct: 10450 YIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10500
Score = 147 bits (357), Expect = 2e-34
Identities = 111/397 (27%), Positives = 173/397 (43%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG PQ+ + D ++T+ W DGG+P+ GY VE W + +V
Sbjct: 14762 PGPPGTPQVTAVTKD----SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14817
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+GL Y+FRV A N G S S+ S+ + PV +
Sbjct: 14818 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 14877
Query: 197 LENDKVE----FHVTFSGIPS---PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
L+ K E F +T + P W K ++ ++ + F I
Sbjct: 14878 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 14937
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I + + A+T R +E APK++ +++D ++ + E L+ + G+P
Sbjct: 14938 NAAGAI--SPPSEPSDAIT-CRDDVE-APKIKVDVKFKDTVILKAGEAFRLEADVSGRPP 14993
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PT+EW DG + ++EI I + L + R D G Y + A N G F V
Sbjct: 14994 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK 15053
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P PP ++VT + L W PP DDGG K+ +YIV+ T W + +
Sbjct: 15054 VLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQ 15113
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L++G+EY FR+ A + YG+ P ES PV
Sbjct: 15114 VTKLKVTKLLKGNEYIFRVMAVNKYGVGEP-LESEPV 15149
Score = 143 bits (347), Expect = 3e-33
Identities = 110/397 (27%), Positives = 167/397 (42%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P I D ++ ++W ++GG+P+ GY +E S W + I+
Sbjct: 16926 PGPPGTPFATAISKD----SMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIH 16981
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ LE +Y+FRV A N VG S+ S+ D P+ +KR E
Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT 17041
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ +G P W K + + ++ F I
Sbjct: 17042 LQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAK 17101
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I ++ G K + L P++ ++ D ++ ET L+ + GKP
Sbjct: 17102 NAAGAIS-KPSDSTGPITAKDEVEL---PRISMDPKFRDTIVVNAGETFRLEADVHGKPL 17157
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTIEW I R EI T ++L + A R D G+Y ++A N+ G + V
Sbjct: 17158 PTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVK 17217
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V VT + +L W PP DGG + +Y+VE T W +
Sbjct: 17218 VLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVV 17277
Query: 429 TN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
TN + + L+EG+EY FRI A + YG+ P ES+PV
Sbjct: 17278 TNSLKVTKLLEGNEYVFRIMAVNKYGVGEP-LESAPV 17313
Score = 143 bits (346), Expect = 3e-33
Identities = 111/397 (27%), Positives = 176/397 (44%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++ + S D ++ ++W DGG+ + GY +E S W++ +
Sbjct: 15844 PGPPGTP-VVTLSSRD---SMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIP 15899
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ + TGLE +Y+FRV+A N VG S++S+ D + + + R
Sbjct: 15900 QTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVT 15959
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + +T F I
Sbjct: 15960 LQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIAR 16019
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++ P++ +Y+D ++ E+ + I GKP
Sbjct: 16020 NAAGVFSEPSESTG--AIT-ARDEVDP-PRISMDPKYKDTIVVHAGESFKVDADIYGKPI 16075
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTI+W + R+EI T + L + A R D G Y ++AKN+ GE + V
Sbjct: 16076 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V ++ + TL W+PP DGG + NYIVE T VW + +
Sbjct: 16136 VLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16195
Query: 429 T-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L+EG+EY FRI A + YG+ P ES PV
Sbjct: 16196 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEP-LESEPV 16231
Score = 142 bits (343), Expect = 8e-33
Identities = 110/402 (27%), Positives = 166/402 (41%), Gaps = 23/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P++ I D ++ + WA DGG + GY +E W + +
Sbjct: 18405 PGPPSTPEVSAITKD----SMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRVAA N G SE S V + D P ++ D +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS-VFYRACDALYPPGPPSNPKVTDTSR 18519
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G +P + + E + T T F + E
Sbjct: 18520 SSVSLAWSKPIYDG-GAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18578
Query: 257 ---CTATNRG--------GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
C + G G V + R+ P++ ++ + T+ L TI
Sbjct: 18579 FRICAINSEGVGEPATLPGSVVAQERI---EPPEIELDADLRKVVVLRASATLRLFVTIK 18635
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P P ++W I+TD R +I +T F++L I + R D G Y + +N G TA
Sbjct: 18636 GRPEPEVKWEK-AEGILTD-RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAF 18693
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
V V P P N+++ SVTL WEPP DGG K+ NYIVE T +
Sbjct: 18694 VNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITN 18753
Query: 426 S-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ KT + +L EG Y FR+ A + YG+ P+ + PV++
Sbjct: 18754 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795
Score = 140 bits (340), Expect = 2e-32
Identities = 112/412 (27%), Positives = 182/412 (44%), Gaps = 28/412 (6%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P+ P ++ + D I + W DGG+P+ GY +E S W++ +
Sbjct: 12593 GVPSEPKNARVTKVNKD----CIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 12648
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V E GL +Y FR+ ALN G S S+ ++ +T R +PP + + DV
Sbjct: 12649 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA---RMPVDPPGKPEVI-DV 12704
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTA---ITTDESTSVLLF--- 244
T + G S I +F + ++ + TA I +E T+ L
Sbjct: 12705 TKSTVSLIWARPKHDG-GSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKA 12763
Query: 245 -HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+Q + + + VT L P++ + L + + L T
Sbjct: 12764 QYQFRAIARTAVNISPPSEPSDPVTI--LAENVPPRIDLSVAMKSLLTVKAGTNVCLDAT 12821
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP PT+ W+ DG + + I++++ L++ S R D G+Y I A+N G +
Sbjct: 12822 VFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 12881
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK- 422
A + V P PP +V + + L WEPP +DGG ++ NYIV+ T W +
Sbjct: 12882 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 12941
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGM-----SAPSSESSPVRIPGR 469
+ T T+ ++ LIEG EY+FRI AE+ YG+ + P+ +P PGR
Sbjct: 12942 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGR 12993
Score = 138 bits (334), Expect = 1e-31
Identities = 116/406 (28%), Positives = 174/406 (42%), Gaps = 26/406 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P I+ + D +++L W GG+P+ GY +E S W R +
Sbjct: 13679 PDAPPPPNIVDVRHD----SVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIR 13734
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +Y+FRV A+N G S S+ V+ + +P V VT
Sbjct: 13735 MRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT 13794
Query: 196 ALEND-KVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + K + +G P+ +W K ++ +T F
Sbjct: 13795 LIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAK 13854
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEA--APKLRYPRQYEDGLLYEINETIFLKT-TIVG 306
+ G I + + T+ +C + AP + +DGL + +TI L +I+G
Sbjct: 13855 NTAGAISAPSES------TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 13908
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
KP P W G I D +I+ TP S+L I A R D GEY I A N G
Sbjct: 13909 KPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHV 13968
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKA 423
VTV P PP V ++ + TL W PP +DGG + +YI+E T W V +
Sbjct: 13969 KVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED 14028
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I S + T LI+G+EY FR+ A + YG P +S PV++ R
Sbjct: 14029 IQSCRHVAT--KLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDR 14071
Score = 138 bits (333), Expect = 1e-31
Identities = 112/405 (27%), Positives = 183/405 (45%), Gaps = 28/405 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIV 135
P P P + ++D I + W P +GG+P+ GY VE +G+ +W+R + PI
Sbjct: 7784 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7843
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
V G+ P +Y RV A+N +G S SE+S+ + V+ D + P D+
Sbjct: 7844 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCK--PTIDLETHDII 7900
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+E +K+ V F +P PT++W KD E+ +S R + D ++ L + + +D G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 7960
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT--PTIE 313
T N+ G A + + P + D T G P +E
Sbjct: 7961 TITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLE 8020
Query: 314 WRHDGH----PIITDDRIEISITPKFSV------LKIHSAKRSDRGEYQIQAKN-IIGED 362
R G P+++ + ++S T K + ++ + + GEY I+ KN +I +D
Sbjct: 8021 RREAGRRTYIPVMSGEN-KLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQD 8078
Query: 363 TAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
PPDPP +V V +++T+ W+PP DGG K+ YI+E G W +
Sbjct: 8079 P-------KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR 8131
Query: 423 AITSRK--TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
T L EG EY+FR++AE+ G+S PS + P +
Sbjct: 8132 CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTK 8176
Score = 137 bits (332), Expect = 2e-31
Identities = 109/407 (26%), Positives = 169/407 (41%), Gaps = 16/407 (3%)
Query: 65 PRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K + +A P PPGKP++I + + ++L WA HDGG+ + GY VE +L
Sbjct: 12680 PSKPTEYVTARMPVDPPGKPEVIDVTK----STVSLIWARPKHDGGSKIIGYFVEACKLP 12735
Query: 124 STEWIR--TAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
+W+R TAP + + E TGLE +YQFR A V S SE SD +T+ ++
Sbjct: 12736 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12795
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ + +T V T G P PT++W KD + + + +
Sbjct: 12796 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT 12855
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D G+ TA N G A + L+ K P + +Y + +
Sbjct: 12856 LELFSVNRKDSGDYTITAENSSGS--KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWE 12913
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + + D + ++S T + + +++I A+N G
Sbjct: 12914 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGV 12973
Query: 362 DTAAFLVTVTA--PPDPPRNVS--VTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTG 416
F A P DPP V + K +T+ W+PPADDGG + Y++E T
Sbjct: 12974 GDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQ 13033
Query: 417 WNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K TL L EG+EY+FR+ A + G PS S
Sbjct: 13034 AVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDAS 13080
Score = 136 bits (330), Expect = 3e-31
Identities = 106/380 (27%), Positives = 170/380 (44%), Gaps = 20/380 (5%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+SD + + WAP +DGG+ + Y VE W T P V + +T L P
Sbjct: 12210 VSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-STVTPEVKKTSFHVTNLVPG 12268
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
++Y FRV A+N+ G +++ + S + +PP ++LE +N T
Sbjct: 12269 NEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPP---RKLEATEMTKNS-----ATL 12320
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVL--LFHQILPSDEGE---IKCTATN 261
+ +P K D I S R D T SV+ L + EG+ + A N
Sbjct: 12321 AWLPPLRDGGAKIDGYIISYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 12380
Query: 262 RGGHAVTK-ARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
G ++ + A EA +L P+ + + + + + ++ + GKP PT +W+
Sbjct: 12381 AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGED 12440
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++T + + S+L I R D G Y + A+N G DT V V P PP+
Sbjct: 12441 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12500
Query: 380 VSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLI 437
+D + +L W P +DGG + NYIVE W+ A+ S KT+ + LI
Sbjct: 12501 PFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLI 12560
Query: 438 EGSEYKFRIKAESPYGMSAP 457
G EY FR++AE+ +G+S P
Sbjct: 12561 PGQEYIFRVRAENRFGISEP 12580
Score = 134 bits (324), Expect = 2e-30
Identities = 117/397 (29%), Positives = 170/397 (42%), Gaps = 25/397 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPGKP +P+ + + +TLKWA + GG + Y VE L + W++ +L
Sbjct: 14862 PPGKP--VPL--NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 14917
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL Y+FRV A N G S SE SD +T D + + V +K + V
Sbjct: 14918 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILK 14977
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W KD E+ + + I + ++ L+ D G
Sbjct: 14978 AGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTL 15037
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHD 317
TATN GG A K ++ + P +G L + E K + P
Sbjct: 15038 TATNPGGFA--KHIFNVKVLDRPGPP----EGPL-AVTEVTSEKCVLSWFPPLDDGGAKI 15090
Query: 318 GHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIG-----EDTAAF 366
H I+ T ++ + V K+ K EY ++ A N G E
Sbjct: 15091 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15150
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V PPDPP+N VT S+ + W P DGG ++ NYIVE W+K
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15210
Query: 427 RKTNV--TLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ + L EG EY+FRI AE+ G+SAPS S
Sbjct: 15211 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 15247
Score = 133 bits (322), Expect = 3e-30
Identities = 116/431 (26%), Positives = 177/431 (41%), Gaps = 21/431 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + S+ ++ L W DGG+ + Y VE + S +W + +
Sbjct: 10813 PGPPRDLEV-SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10871
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++Y FRVAA N G + E + PP + + DV E
Sbjct: 10872 FA-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEV 10929
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
V G SP + + E + T + ++ + + A
Sbjct: 10930 SLVWNKPDRDG-GSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTG-LQQGKTYRFRVKA 10987
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYED-----GLLYEINETIFLKTTIVGKPTPTIEW 314
N G + + +E KL P D GL+ + T+ I G P PT +W
Sbjct: 10988 ENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKW 11047
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
DG I TD+ + SVL I + R D GEYQI N G T A +TV P
Sbjct: 11048 TTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP 11107
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVT 432
PP +++ + +T+ W+PP DDGG V NYIVE T + W + + S KT +
Sbjct: 11108 GPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLK 11167
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSES--------SPVRIPGRAIDMDFLAVEARIIN 484
+ L +G EY FR++AE+ G+ P + SP PG+ + D + A ++
Sbjct: 11168 IPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAATVS 11226
Query: 485 EALTREDGEEP 495
L + DG P
Sbjct: 11227 WTLPKSDGGSP 11237
Score = 132 bits (320), Expect = 5e-30
Identities = 113/420 (26%), Positives = 171/420 (40%), Gaps = 17/420 (4%)
Query: 54 NHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR 113
NHY +P ++ K R PPG P+ P +S+ N T+ W DGG+ +
Sbjct: 14053 NHYGKG----EPVQSEPVKMVDRFGPPGPPEK-PEVSNVTKNTATVSWKRPVDDGGSEIT 14107
Query: 114 GYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
GY VE S W+R V +TGL+ Y+FRV+A N G SE SD +
Sbjct: 14108 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSV 14167
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
+ D A P + D T + G T + + ++
Sbjct: 14168 LMK-DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT-GYVVEHQKVGDEAWIKD 14225
Query: 234 TTDESTSVLLF--HQILPSDEGEIKCTATNRGG----HAVTKARLC-LEAAPKLRYPRQY 286
TT + + F + ++ + +A N G + + E AP +
Sbjct: 14226 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAEL 14285
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS 346
L+ +I + I G+P P + W D I +R I T F++L I R
Sbjct: 14286 RRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKNRANIENTESFTLLIIPECNRY 14343
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D G++ + +N G+ + V V P P N+ T SVTL W+ P DGG ++
Sbjct: 14344 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 14403
Query: 407 NYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
NYIVE + A T K + L EG EY FR+ AE+ YG+ P+ + PV+
Sbjct: 14404 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVK 14463
Score = 132 bits (319), Expect = 6e-30
Identities = 102/399 (25%), Positives = 177/399 (44%), Gaps = 21/399 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P + + + +IT+ W +GG+ + GY +E S W + ++
Sbjct: 20173 PGPPSTPWVTNVTRE----SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIR 20228
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+T + Y+FRV A N G S S+ VL + + EPP + R+ D++
Sbjct: 20229 TTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC----EPPRNV-RITDIS 20283
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLLFHQILPSDEGE 254
F G S + + ++ R T A T+ + + + + + E
Sbjct: 20284 KNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTETQFTISGLTQNSQYE 20342
Query: 255 IKCTATNRGGHAVTKARL-----CLEA--APKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ A N G + + C+++ P + P +Y + + Y ++ L+ I GK
Sbjct: 20343 FRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20402
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PTIEW D + T+ + + T + + I A R + G Y+++ +N + +A
Sbjct: 20403 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMASASATIR 20462
Query: 368 VTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAIT 425
V + P PP + + +TL W PPADDGG K+ +YIVE T VW + +
Sbjct: 20463 VQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEH 20522
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +T +I+G+EY FR++A + YG+ P S V
Sbjct: 20523 LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 20561
Score = 132 bits (318), Expect = 9e-30
Identities = 105/398 (26%), Positives = 167/398 (41%), Gaps = 15/398 (3%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P++ + D ++ + W DGG+ + GY +E W R ++
Sbjct: 16240 PDAPKAPEVTTVTKD----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIG 16295
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRV+A N G S S S PP K ++ +
Sbjct: 16296 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 16355
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G K D + T + + + ++L E +
Sbjct: 16356 SVFLSWSKPIYDGGCEIQGYIVEKCDVNVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFR 16415
Query: 257 CTATNRGG---HAVTKARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
A N+ G HA + +E AP + + + ++ L I G+PTP
Sbjct: 16416 ICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTP 16475
Query: 311 TIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
++W + DG I D I I +T F+ L + + R D G+Y + +N G +A V
Sbjct: 16476 EVKWGKVDGE--IRDAAI-IDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVR 16532
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RK 428
V P PP N+ VT SV++ WEPP DGG K+ NYIVE + +T+ K
Sbjct: 16533 VLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHK 16592
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + L EG Y FR+ AE+ YG+ P+ + P+++
Sbjct: 16593 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV 16630
Score = 131 bits (317), Expect = 1e-29
Identities = 115/400 (28%), Positives = 169/400 (42%), Gaps = 25/400 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P+ + + D+ ++L W DGG+P+ GY VE G+ +WI+ V
Sbjct: 10912 PPGPPKDLHHVDVDKTE-VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT--VTNL 10968
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP---VFIKRLEDVT 195
E V+TGL+ Y+FRV A N VG L D + PP + +K +E +
Sbjct: 10969 ECVVTGLQQGKTYRFRVKAENIVGLG----LPDTTIPIECQEKLVPPSVELDVKLIEGLV 11024
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
V F G+P PT W D EI + + TD +SVL L D GE
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIE 313
+ T +N G L + P P +L E TI + +P I
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLDVPG---PPTGPINILDVTPEHMTISWQPPKDDGGSPVIN 11141
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV 368
+ + D +S + LKI ++ ++++A+N IG + T
Sbjct: 11142 YIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAK 11201
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TG-W-NVWLKAIT 425
+PP PP VT + + T+ W P DGG + Y +E TG W V I
Sbjct: 11202 HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIA 11261
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
K VT L EG+ Y+FR+ AE+ G+S PS S P++
Sbjct: 11262 DLKFRVT--GLYEGNTYEFRVFAENLAGLSKPSPSSDPIK 11299
Score = 131 bits (317), Expect = 1e-29
Identities = 113/399 (28%), Positives = 178/399 (44%), Gaps = 24/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP KP+I+ D IT+ W DGGAP+ GY VE + T+W +T+ +
Sbjct: 19587 PSPPSKPKIV----DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLR 19641
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLEDVT 195
E ++GL +Y FRV ++N VG S+ S+ SD ++ +R +E P+F I T
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP-QIAKER--EEEPLFDIDSEMRKT 19698
Query: 196 ALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ F +T F G P P + W K D ++ +R TTD TS L +D G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAYVDTTDSRTS-LTIENANRNDSG 19756
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPTPTI 312
+ T N ++ A L L L P + + ++ E+ L +
Sbjct: 19757 KYTLTIQN----VLSAASLTL-VVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 19811
Query: 313 EWRHDGHPIITDDRIEISITPKFSVL--KIHSAKRSDRGEYQIQAKNIIGEDTAAFL--- 367
+ + +S+T + L K+ + + +++ +N G A
Sbjct: 19812 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG 19871
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V +T P PP + VT SV+L W P DGG ++ +Y+VE G W+K ++
Sbjct: 19872 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 19931
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ + L E SEY FR+ AE+ G+S P PV I
Sbjct: 19932 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLI 19970
Score = 130 bits (315), Expect = 2e-29
Identities = 101/387 (26%), Positives = 167/387 (43%), Gaps = 16/387 (4%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P PI+ D N++ +KW D G+P+ GY +E + ST W R ++
Sbjct: 8405 PPDAPDK-PIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNAL 8462
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+ + GL Y FRV A N G +S SD T + PP I R+ D ++
Sbjct: 8463 KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTDTSSTT 8520
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF--HQILPSDEGEIK 256
+ F+G + +F D ++ + + + T++ V + +I + +++
Sbjct: 8521 IELEWEPPAFNG-GGEIVGYFVDK-QLVGTNKWSRCTEKMIKVRQYTVKEIREGADYKLR 8578
Query: 257 CTATNRGGHAVTKARLCLEAA-----PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+A N G + A P + + G+ +T+ + + G+P PT
Sbjct: 8579 VSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPT 8638
Query: 312 IEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
W + +G + DR+ I S L I A R D G Y I A N G AA V V
Sbjct: 8639 KVWTKEEGE--LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
P P ++ K L+W P DDGG ++ +I+E + W + I + ++
Sbjct: 8697 FDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSK 8756
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ L+EG EYKFR+ A++ +G P
Sbjct: 8757 CDITGLLEGQEYKFRVIAKNKFGCGPP 8783
Score = 130 bits (315), Expect = 2e-29
Identities = 101/412 (24%), Positives = 169/412 (41%), Gaps = 15/412 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+ P++S+ + +T+ W P DGG+P+ GY +E + W + ++
Sbjct: 12990 PPGRCDP-PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIER 13048
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L TGL+ +Y+FRV A+N G S+ S + PP F K + D T
Sbjct: 13049 TLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPK-VYDTTRSS 13107
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGEIK 256
+ G SP I + + S ++ F ++ + + +
Sbjct: 13108 VSLSWGKPAYDG-GSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFR 13166
Query: 257 CTATNRGGHA----VTKARLCLEAA--PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
A N+ G++ V + P+ + L+ T+ L + G+P P
Sbjct: 13167 VYAVNKIGYSDPSDVPDKHYPKDILIPPEGEHDADLRKTLILRAGVTMRLYVPVKGRPPP 13226
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W + ++I T + L+ + + D G+Y + +N G+ +V V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKT 429
P PP NV+V S + WEPP DGG + NY+V+ W T KT
Sbjct: 13287 LDTPGPPINVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT 13346
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAIDMDFLAV 478
+ + +L EG Y FR+ AE+ YG+ P V+ PG +D+ +V
Sbjct: 13347 SFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSV 13398
Score = 129 bits (312), Expect = 5e-29
Identities = 104/398 (26%), Positives = 167/398 (41%), Gaps = 19/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P + I D + ++W +DGG + GY +E S W++ +
Sbjct: 18008 PGPPGTPFVTSISKDQ----MLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 18063
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ TGL+ +Y+F+V+A N VG S++S+ D + + I R
Sbjct: 18064 DTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVT 18123
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + ++ F I
Sbjct: 18124 LKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIAR 18183
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++A P +Y+D ++ ET L+ I GKP
Sbjct: 18184 NAAGNFSEPSDSSG--AIT-ARDEIDA-PNASLDPKYKDVIVVHAGETFVLEADIRGKPI 18239
Query: 310 PTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W DG + T R+EI T + + L + R+D G+Y ++ N+ G + V
Sbjct: 18240 PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18299
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P P + VT + L W PP DGG + +YI+E T W + T
Sbjct: 18300 KVLDRPGSPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV 18359
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ N + L+ G+EY FR+ A + YG+ P ES PV
Sbjct: 18360 QALNYKVTKLLPGNEYIFRVMAVNKYGIGEP-LESGPV 18396
Score = 129 bits (312), Expect = 5e-29
Identities = 105/402 (26%), Positives = 174/402 (43%), Gaps = 22/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P++ I N++T+ W+ DGG+ + GY +E S W + +
Sbjct: 20569 PGPPGIPEVTKITK----NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 20624
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+TGL YQ+RV A+N G +SE S+ + PP I R+ D T
Sbjct: 20625 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKI-RIADSTK 20683
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT--DESTSVLLFHQILPSDEGE 254
+ G S + + + T ++T + T+ + + P
Sbjct: 20684 SSITLGWSKPVYDG-GSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYY 20742
Query: 255 IKCTATNRGGHAV-------TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ +A N G +A+ LEA P++ ++ + E + + G+
Sbjct: 20743 FRVSAVNCAGQGEPIEMNEPVQAKDILEA-PEIDLDVALRTSVIAKAGEDVQVLIPFKGR 20801
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ WR D + +D R I T S+L I R+D G+Y + +N +GE ++ +
Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861
Query: 368 -VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P + + V +VTL W+PP DGG + NY++E W ++ S
Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTW--SVVS 20919
Query: 427 RKTNVTLFDLIEGSE---YKFRIKAESPYGMSAPSSESSPVR 465
K + T F LI+ SE + FR+ AE+ G+ P + PV+
Sbjct: 20920 HKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK 20961
Score = 128 bits (310), Expect = 8e-29
Identities = 119/462 (25%), Positives = 193/462 (41%), Gaps = 36/462 (7%)
Query: 65 PRKNVHWKSA-GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K V K +P+PP P+ I D N++ L W P HDGG+ + GY VE ++G
Sbjct: 10603 PSKPVFAKDPIAKPSPPVNPEAI----DTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG 10658
Query: 124 STEWIRT--APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
EW R P + +TGL Y+FRV A+N G S+ + + + + V DR
Sbjct: 10659 DEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRL- 10716
Query: 182 QEPPVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
EPP I + D + G+P P + W K+D + + R +T
Sbjct: 10717 -EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVT--PV 10773
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
S L D G T N G ++ + P PR E + + + +
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP--GPPRDLEVSEIRKDSCYL 10831
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE---YQIQA 355
K + + + + + + +S T K K H AK + G +++ A
Sbjct: 10832 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK---KKSHFAKHLNEGNQYLFRVAA 10888
Query: 356 KNIIGE----DTAAFLVTVTA--PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNY 408
+N G +T + + PP PP+++ VDK+ V+L W P DGG + Y
Sbjct: 10889 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEVSLVWNKPDRDGGSPITGY 10947
Query: 409 IVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV---- 464
+VEY G W+K T + L +G Y+FR+KAE+ G+ P + + P+
Sbjct: 10948 LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 11006
Query: 465 RIPGRAIDMDFLAVEARIINEALTREDGEEPRISPAPRRKRT 506
++ ++++D +E ++ T R P P K T
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT 11048
Score = 128 bits (309), Expect = 1e-28
Identities = 97/377 (25%), Positives = 156/377 (41%), Gaps = 17/377 (4%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++TL W P DGGA + Y VE R + + T + + L+ Y FR
Sbjct: 18716 DSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFR 18774
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSP 214
V A N+ G +E ++ + VS EPP+ R+ V N
Sbjct: 18775 VLASNEYGIGLPAETTEPVKVS------EPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18828
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA------VT 268
I + + + S + + T T + +E + A N G + V
Sbjct: 18829 KITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP 18888
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+E P + P + + E + + G+P T+ WR DG + R+
Sbjct: 18889 VIARDIEIKPSVELPFHTFN---VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 18945
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
+S + + L I A + D G Y++ N G T + V P PP + +
Sbjct: 18946 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 19005
Query: 389 SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVTLFDLIEGSEYKFRIK 447
S+T+ W PP DGGC++ NYIVE T W + + +T++ + L GSEY+FR+
Sbjct: 19006 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19065
Query: 448 AESPYGMSAPSSESSPV 464
AE+ YG S+ S S+ V
Sbjct: 19066 AENRYGKSSYSESSAVV 19082
Score = 127 bits (306), Expect = 2e-28
Identities = 108/398 (27%), Positives = 168/398 (42%), Gaps = 19/398 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ RP PPGK ++ + N+++L W HDGG+ + GY VE GS +W A
Sbjct: 15547 KASERPLPPGKITLMDVTR----NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA 15602
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V E +TGL +Y FRV+A N+ G S+ +LS V ++ D PP F
Sbjct: 15603 TVKVT--EATITGLIQGEEYSFRVSAQNEKGISDPRQLS-VPVIAKDLVI--PPAFKLLF 15657
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
T L + ++ V F G P+P + W KD+ + + R + E+ S+L D
Sbjct: 15658 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRED 15717
Query: 252 EGEIKCTATNRGGHAV-TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G TN G A+ T + L+ P + ++ I T+ +
Sbjct: 15718 VGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSI--TLSWGPPKYDGGSS 15775
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ + T +S T + +K K +++I A+N G+ T
Sbjct: 15776 INNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPT 15835
Query: 371 TAP-----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
A P PP VT S+ + W P DGG +V Y +E +W+K
Sbjct: 15836 VAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNK 15895
Query: 426 S--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ +T L EG EY+FR+ AE+ G+ PS S
Sbjct: 15896 TPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Score = 127 bits (306), Expect = 2e-28
Identities = 101/393 (25%), Positives = 175/393 (44%), Gaps = 17/393 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP ++ I D ++++ W P DGG+ ++ Y VE R + +
Sbjct: 16537 PSPPVNLKVTEITKD----SVSITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCH 16591
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ + L+ Y FRV A N+ G ++ +D + V+ +PP I ++DVT
Sbjct: 16592 KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKIT-VDDVTR 16647
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
G S I + + S + + +S ++ + + +E +
Sbjct: 16648 NSVSLSWTKPEHDG-GSKIIQYIVEMQAKHSEKWSECARVKSLQAVITN-LTQGEEYLFR 16705
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL---YEINETIFLKTTIVGKPTPTIE 313
A N G + ++ A L + ++ + + ++ I G+P PTI
Sbjct: 16706 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKMEVPISGRPKPTIT 16765
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG P+ RI ++ + + L I + D G+Y I N++G+ TA+ +
Sbjct: 16766 WTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16825
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
PDPP+ V +S+TL W PP GGC++ NYIV+ T VW + + T +T +
Sbjct: 16826 PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL 16885
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L G+EY+FRI AE+ YG S + ES P+
Sbjct: 16886 KVTKLKTGTEYQFRIFAENRYGQSF-ALESDPI 16917
Score = 126 bits (305), Expect = 3e-28
Identities = 73/191 (38%), Positives = 96/191 (50%), Gaps = 2/191 (1%)
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
+ AP++ + GL + I L T+ GKP P I W + D RI I PK
Sbjct: 7188 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 7247
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW 394
S + I +KRSD G Y I+A N+ G TA V V P PP +T ++S L W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PP DDGG K+ NY+VE T VW K + T + TN LI EY FR+ AE+ YG
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7367
Query: 454 MSAPSSESSPV 464
P ++SP+
Sbjct: 7368 AGEP-VQASPI 7377
Score = 126 bits (304), Expect = 4e-28
Identities = 108/397 (27%), Positives = 165/397 (41%), Gaps = 19/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP I + SD ++L W +DGG+ + G+ VE S W + +
Sbjct: 21260 PGPPGKPVIYNVTSD----GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 21315
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E TGL YQFRV A N G S+ S+ S S P +I DVT
Sbjct: 21316 GREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI----DVTR 21371
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E ++++ S + + + + TD S + P D E +
Sbjct: 21372 -ETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFR 21430
Query: 257 CTATNRGGHAVTKARLC-------LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
A N G ++ P + + +Y DGL+ + E++ +K + G+P
Sbjct: 21431 IIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPV 21490
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P + W DG I +EI+ + L + A R RG Y ++AKN G A V
Sbjct: 21491 PRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21550
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSR 427
V P + T + +TL W+ P +DG + +YI+E T W L
Sbjct: 21551 VQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCE 21610
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T LI G+EY+FR+ A + +G+ P +S PV
Sbjct: 21611 AQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPV 21646
Score = 125 bits (302), Expect = 7e-28
Identities = 105/402 (26%), Positives = 167/402 (41%), Gaps = 25/402 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+ P +P++ + + NA++++W HDGG+ + GY VE + W++ L
Sbjct: 22344 PSAPTRPEVYHVSA----NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCL 22399
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPPVF------IK 189
+TGL +YQFR ALN G S SE S ++ + A P V +
Sbjct: 22400 ECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVS 22459
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
+ A + P + W K +Y I S +T F
Sbjct: 22460 LIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRV 22519
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYP-RQYEDGLLYEINETIFLKTT 303
+ + G I + + G VT C + A PK R + D + + L
Sbjct: 22520 LAKNAAGVISKGSESTG--PVT----CRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 22573
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP P I W + +++ + T K + I RSD G+Y + KN G
Sbjct: 22574 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 22633
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ +V V P P ++V+R + TL W P +DGG ++ +YIVE T W+
Sbjct: 22634 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 22693
Query: 424 ITSRKT-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + LI+ +EY FR++A + YG P ES P+
Sbjct: 22694 EGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVP-VESEPI 22734
Score = 124 bits (299), Expect = 2e-27
Identities = 104/397 (26%), Positives = 171/397 (43%), Gaps = 18/397 (4%)
Query: 71 WKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT 130
+K+A PPG P I I +D ++ITL W+ +DGG+ + GY VE + EW
Sbjct: 20661 YKAADPIDPPGPPAKIRI-ADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTV 20719
Query: 131 APPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
+ +R E V++ L+P Y FRV+A+N G E+++ + + E + +
Sbjct: 20720 STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
V A + V+ + F G P PT+ W KD+ + S R +I +S+S+L Q+
Sbjct: 20780 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 20839
Query: 250 SDEGEIKCTATNRGGH----AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+D G+ T N G V+ L AA + + G + T+ ++
Sbjct: 20840 NDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV-----TLLWDPPLI 20894
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG----- 360
+P I + + +S + K+ +++ A+N IG
Sbjct: 20895 DGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC 20954
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
E T V P P R++S+ SV L W P DGG + Y+VE G W
Sbjct: 20955 ETTEP--VKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW 21012
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
A S+ + + L E S +FR+ A++ G+S P
Sbjct: 21013 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 21049
Score = 124 bits (298), Expect = 2e-27
Identities = 112/426 (26%), Positives = 181/426 (42%), Gaps = 43/426 (10%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR- 137
PPG P P ++D + +L W +DGG + GY VE ++G WI+ LR
Sbjct: 14175 PPGPPSN-PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI 14233
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKRLEDVTA 196
+ V+ L+ KY FR++A+ND G + + DV V + A E ++R V A
Sbjct: 14234 TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA 14293
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V G P+P + W KD+ + R I ES ++L+ + D G+
Sbjct: 14294 --GLSIRIFVPIKGRPAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFV 14349
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
T N G + + P + L+ T + K + T+ W
Sbjct: 14350 MTIENPAGKKSGFVNVRVLDTP----------------GPVLNLRPTDITKDSVTLHWDL 14393
Query: 317 ---DGHPIITDDRIEISITPKFS----VLKIHSAKRSDRG-----EY--QIQAKNI--IG 360
DG IT+ +E + S K H G EY ++ A+N IG
Sbjct: 14394 PLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIG 14453
Query: 361 EDTAAFL-VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
E T V + P PP ++++ +V+L W P DGG K+ Y++E R G +
Sbjct: 14454 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14513
Query: 420 WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI--DMDFLA 477
W T + + +L EG EY F++ A + G SAP ES PV + + + ++D
Sbjct: 14514 WTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRG 14572
Query: 478 VEARII 483
+ +++
Sbjct: 14573 IYQKLV 14578
Score = 123 bits (297), Expect = 3e-27
Identities = 109/402 (27%), Positives = 177/402 (44%), Gaps = 24/402 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
RP+PP + SD +++ LKW P DGG+P+ GY +E G WIR +V
Sbjct: 6794 RPSPP----VNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLV 6849
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+TGLE +KY +RV+A N G S+ SE+ LT +D A EP + + +D +
Sbjct: 6850 PELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLT--ADDAFVEPTMDLSAFKDGL 6907
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ + + V +G P PT W D + + R + T + + L+ SD+G
Sbjct: 6908 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 6967
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TI 312
NR + + + A P ++ D ++ T G P +
Sbjct: 6968 YTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVV 7027
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VT 369
E R T ++ +F+V + K +++ A+N G A++ V
Sbjct: 7028 EKREVSRKTWT-KVMDFVTDLEFTVPDLVQGKEY---LFKVCARNKCGPGEPAYVDEPVN 7083
Query: 370 VTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL---KA 423
++ P PDPP NV + S+ L W+PP +DGG ++ YIVE G + W+ +
Sbjct: 7084 MSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP 7143
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ K VT L EG Y +R+K + G S PS + ++
Sbjct: 7144 VAETKMEVT--GLEEGKWYAYRVKTLNRQGASKPSRPTEEIQ 7183
Score = 123 bits (297), Expect = 3e-27
Identities = 101/391 (25%), Positives = 172/391 (43%), Gaps = 19/391 (4%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH 149
+D +++TL W DGG+ + Y VE R + + TA + +TGL
Sbjct: 14380 TDITKDSVTLHWDLPLIDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGC 14438
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+Y FRV A N+ G +E ++ + S + PP + + D+T
Sbjct: 14439 EYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLN-IMDITKSTVSLAWPKPKHD 14494
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G S + + S + T ITT + ++ + +E + A N G + +
Sbjct: 14495 G-GSKITGYVIEAQRKGSDQWTHITTVKGLECVV-RNLTEGEEYTFQVMAVNSAGRSAPR 14552
Query: 270 AR---LCLEAA--PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
+ E P+L Y+ ++ + + I ++ ++G+P PT+ W+ +
Sbjct: 14553 ESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQT 14612
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR 384
R+ T ++L I+ RSD G Y + A+NI+GE + V P PP
Sbjct: 14613 QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFD 14672
Query: 385 QVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEY 442
+V VT W+PP +DGG + NY+VE +T W++ A T +T L G EY
Sbjct: 14673 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEY 14732
Query: 443 KFRIKAESPYGM-----SAPSSESSPVRIPG 468
+FR+KA++ YG+ SA + P ++PG
Sbjct: 14733 QFRVKAQNRYGVGPGITSAWIVANYPFKVPG 14763
Score = 123 bits (296), Expect = 4e-27
Identities = 102/393 (25%), Positives = 168/393 (42%), Gaps = 20/393 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + + + +A + W P DGG+P+ Y V+ W T +
Sbjct: 13290 PGPPINVTVKEISKDSAY-VTWEPPIIDGGSPIINYVVQKRDAERKSW-STVTTECSKTS 13347
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ LE Y FRV A N+ G + E D + +ASQ P PV ++ V+
Sbjct: 13348 FRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAV-----KASQTPGPVVDLKVRSVSK-S 13401
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S S I + D + ++ + S + E + +
Sbjct: 13402 SCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRVMKSLSLQYSA-KDLTEGKEYTFRVS 13459
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL-----LYEINETIFLKTTIVGKPTPTIE 313
A N G T + + + A + P GL L + N LK I GKP P++
Sbjct: 13460 AENENGEG-TPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W+ P+ TD R+ + + + L ++ ++SD G+Y I KN+ G + V
Sbjct: 13519 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 13578
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNV 431
P P + +++TL W PP DDGG ++ NYI+E + N W+ ++ +KT
Sbjct: 13579 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 13638
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L EG EY FR+ AE+ YG+ +S P+
Sbjct: 13639 RVTRLHEGMEYTFRVSAENKYGV-GEGLKSEPI 13670
Score = 123 bits (296), Expect = 4e-27
Identities = 87/391 (22%), Positives = 162/391 (41%), Gaps = 8/391 (2%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P ++ + +D ++L+W+ DGG + GY +E + +W + ++
Sbjct: 21756 PPGPPTVVKV-TDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKTDLGDWHKVNAEACVKT 21814
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+T L+ +Y+FRV+A+N G + E++ + + E + +
Sbjct: 21815 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRA 21874
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + G P+PT W K D + S R I T +S S L +D G+ T
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLT 21932
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
N G + + P P ++D + + T+ ++ + +
Sbjct: 21933 VENNSGSKSITFTVKVLDTPGPPGPITFKD--VTRGSATLMWDAPLLDGGARIHHYVVEK 21990
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VTVTAPPD 375
IS + K++ +++ A N G + + T P
Sbjct: 21991 REASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 22050
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD 435
PPR + V S L W P DGG ++ Y++E + G ++W++A +++ T+
Sbjct: 22051 PPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDLWVEAGHTKQLTFTVER 22110
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
L+E +EY+FR+KA++ G S P S V I
Sbjct: 22111 LVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22141
Score = 123 bits (296), Expect = 4e-27
Identities = 110/397 (27%), Positives = 158/397 (39%), Gaps = 20/397 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + I D + +TL W P DGG+ + GY VE + + W+R V
Sbjct: 23435 PGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 23493
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
TGL +Y+ RV A+N G S S + A P R+ D T
Sbjct: 23494 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQN-PRVTDTTRTSV 23552
Query: 200 D---KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEI 255
V S + I K D ++ T T + L H LP E
Sbjct: 23553 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT--TPTKIREYTLTH--LPQGAEYRF 23608
Query: 256 KCTATNRGGHAV-TKARLCLEAAPKLRYP-----RQYEDGLLYEINETIFLKTTIVGKPT 309
+ A N GG + ++ L YP +Y++G+ I L I GKP
Sbjct: 23609 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 23668
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P +W +G I R I+ + + L I A R D G Y + +N G+ V
Sbjct: 23669 PICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVR 23726
Query: 370 VTAPPDPPRNVSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P+ P + +SV + W PPADDGG + YI+E W + R
Sbjct: 23727 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVR 23786
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T++ + L E EY FR+ AE+ +G+S P PV
Sbjct: 23787 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23823
Score = 122 bits (295), Expect = 5e-27
Identities = 109/402 (27%), Positives = 167/402 (41%), Gaps = 24/402 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + ++TL W P DGG+ ++ Y VE R + + T +
Sbjct: 15455 PGPPQDLKV-KEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCHKTS 15512
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L+ Y FRV A N+ G +E T S +AS+ P P L DVT
Sbjct: 15513 WKVDQLQEGCSYYFRVLAENEYGIGLPAE-----TAESVKASERPLPPGKITLMDVTR-N 15566
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S + + + S + T + T + ++ +E + +
Sbjct: 15567 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG-LIQGEEYSFRVS 15625
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKPTPTIE 313
A N G + + A L P ++ LL+ E + + +G+PTP +
Sbjct: 15626 AQNEKGISDPRQLSVPVIAKDLVIPPAFK--LLFNTFTVLAGEDLKVDVPFIGRPTPAVT 15683
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W D P+ R+ T S+L I A R D G Y ++ N GE V V
Sbjct: 15684 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
P PP V + S+TL W PP DGG + NYIVE T W + + T +T +
Sbjct: 15744 PGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTI 15803
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSA-----PSSESSPVRIPG 468
L G EY+FRI AE+ YG S P+ P ++PG
Sbjct: 15804 KACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPG 15845
Score = 122 bits (294), Expect = 7e-27
Identities = 104/401 (25%), Positives = 173/401 (43%), Gaps = 20/401 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPP-IV 135
P+PPG P+ + + I ++W DGG + Y V+ S W R +V
Sbjct: 22743 PSPPGIPEEVGTGKEH----IIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVV 22798
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +T L YQFRV A+N G+S SE S+ ++ + PP R+ D T
Sbjct: 22799 YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPS-APRVVDTT 22857
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEG 253
+ G + + + + E + + + T+ + F + +
Sbjct: 22858 KHSISLAWTKPMYDG-GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKY 22916
Query: 254 EIKCTATN-RGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEIN----ETIFLKTTIVGK 307
+ A N +G +++ +E ++ P + D L + ++ L ++ G+
Sbjct: 22917 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 22976
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P I W G + + R I T +S+L + R D G+Y I+A+N G+ +A L
Sbjct: 22977 PPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL 23034
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V V P P +V V SVT+ WE P DGG + NYIVE + K +T++
Sbjct: 23035 VKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAF-KTVTTK 23093
Query: 428 --KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
KT + L+EG+ + FR+ E+ YG+ P S V +
Sbjct: 23094 CSKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLV 23134
Score = 122 bits (293), Expect = 9e-27
Identities = 96/402 (23%), Positives = 161/402 (40%), Gaps = 11/402 (2%)
Query: 68 NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW 127
+V +++ PPG P P ++D ++++L W+ +DGGAP++GY VE + EW
Sbjct: 18494 SVFYRACDALYPPGPPSN-PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 18552
Query: 128 IRTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
PP L+ + +T L+ +Y FR+ A+N G + L + V+ +R
Sbjct: 18553 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSV-VAQERIEPPEIE 18611
Query: 187 FIKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
L V L + + VT G P P + W K E + R I S ++L+
Sbjct: 18612 LDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSSFTMLVID 18669
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ D G T N G + + +P P + + + T+ + ++
Sbjct: 18670 NVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--PVNLTIREVKKDSVTLSWEPPLI 18727
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
+ + I+ + +I + + +++ A N G A
Sbjct: 18728 DGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA 18787
Query: 366 FL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
V V+ PP PP V++ + T+ WE P DGG K+ Y+VE G W
Sbjct: 18788 ETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18847
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T+ L G EY FR+ A + G S P PV
Sbjct: 18848 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 18889
Score = 120 bits (290), Expect = 2e-26
Identities = 101/392 (25%), Positives = 166/392 (42%), Gaps = 21/392 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP ++ I D ++T+ W DGG+ + GY VE WI+ +
Sbjct: 17322 PGPPKSLEVTNIAKD----SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRIT 17377
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H+Y+FRV+A N G S + V + D + P + D T
Sbjct: 17378 DLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT-VYYKACDPVFKPGPPTNAHIVDTTK 17436
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEGE 254
+ G S + + + + +T V F ++ E +
Sbjct: 17437 NSITLAWGKPIYDG-GSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYK 17495
Query: 255 IKCTATNRGG-------HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
I+ A N+ G K LEA P+L + G++ + + G+
Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAGGSARIHIPFKGR 17554
Query: 308 PTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W R +G D+++I ++ L I + R+D G+Y ++ +N G +A
Sbjct: 17555 PMPEITWSREEGE---FTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17611
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P PP+N++V S L WEPP DGG KV NY+++ + + +
Sbjct: 17612 TVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSK 17671
Query: 427 -RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
KT+ + +L EG+ Y FR+ AE+ +G+ P
Sbjct: 17672 CSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 17703
Score = 120 bits (289), Expect = 3e-26
Identities = 104/398 (26%), Positives = 166/398 (41%), Gaps = 22/398 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + +A L W P DGGA ++ Y ++ R + + +
Sbjct: 17619 PGPPQNLAVKEVRKDSAF-LVWEPPIIDGGAKVKNYVID-KRESTRKAYANVSSKCSKTS 17676
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L Y FRV A N+ G V TV + +A++ P P L DV+
Sbjct: 17677 FKVENLTEGAIYYFRVMAENEFGVG-----VPVETVDAVKAAEPPSPPGKVTLTDVSQTS 17731
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ G + + + + + + +I + + + E + +
Sbjct: 17732 ASLMWEKPEHDG--GSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVK 17789
Query: 259 ATNRGGHA------VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
A N G + V L P L+ P + E + ++ ++G+P P I
Sbjct: 17790 AYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIPVIGRPRPNI 17846
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ R+ + T +VL I + D G+Y + A N G T V V
Sbjct: 17847 SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE 17906
Query: 373 PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTN 430
P PP +V V + WEPPA GGC++ NYIVE T W + + T +T
Sbjct: 17907 KPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT 17966
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVRIP 467
+ + L G+EY+FRI AE+ YG SAP S++ V+ P
Sbjct: 17967 IKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYP 18004
Score = 119 bits (286), Expect = 6e-26
Identities = 106/396 (26%), Positives = 172/396 (43%), Gaps = 21/396 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG Q + + + + N T+ W +GG+ + + VE + W A + R
Sbjct: 11505 PGPCQNLKVTNVTKENC-TISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR-- 11561
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL-SDVLTVSS-DRASQEPPVFIK-RLEDVTA 196
L+ L ++Y FRV A N VG E + +L ++ DR + + I + +
Sbjct: 11562 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 11621
Query: 197 LENDKVEFHVTFSGIPSPTIAWFK--DDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L+ + ++ + K DD+E R + + T ++ + + + E
Sbjct: 11622 LKWRRPDYDGGSPNLSYHVERRLKGSDDWE-----RVHKGSIKETHYMV-DRCVENQIYE 11675
Query: 255 IKCTATNRGGHA---VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+ N GG + T+ + E K + L + +TI L+ + GKP P
Sbjct: 11676 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 11735
Query: 312 IEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ W D + R++I S + AKRSD G+Y + A N G A V
Sbjct: 11736 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 11795
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRK 428
V P P RN+ + T+ W+PP DDGGC++ NYI+E T VW + T
Sbjct: 11796 VLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 11855
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ LIEG+EY FR++AE+ G + P +ES PV
Sbjct: 11856 PGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPV 11890
Score = 118 bits (285), Expect = 9e-26
Identities = 86/381 (22%), Positives = 166/381 (43%), Gaps = 11/381 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + ++ D + LKW P +DGG P++ Y +E T W++
Sbjct: 7687 PGPPYALAVV-DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7745
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + + QF+V A N+ G + SE +++L++ + PP+ + + ++
Sbjct: 7746 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTD--AGRKH 7803
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD--ESTSVLLFHQILPSDEGEIKC 257
+ + SP I + + + + + + + + + ++P E ++
Sbjct: 7804 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 7863
Query: 258 TATNRGG----HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
A N G +++ + + K + D ++ E E + + P PT+
Sbjct: 7864 RAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE-GEKLSIPVPFRAVPVPTVS 7922
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG + DR+ + + L++ + R+D G Y I +N +G TA+ V V
Sbjct: 7923 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTNVT 432
P P +++ + S L WEPP DGG + +Y++E G ++ ++ K + T
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8042
Query: 433 LFDLIEGSEYKFRIKAESPYG 453
+ DLI EY FR+KA + G
Sbjct: 8043 VKDLIPNGEYFFRVKAVNKVG 8063
Score = 118 bits (285), Expect = 9e-26
Identities = 102/392 (26%), Positives = 159/392 (40%), Gaps = 21/392 (5%)
Query: 86 IPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIVLRPELVLTG 144
IP S+ N+ITL WA DGG+ ++ Y +E ST W++ + + +TG
Sbjct: 21660 IPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21719
Query: 145 LEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED---VTALENDK 201
L ++Y+F V A N G S +S ++ PP +K + +LE K
Sbjct: 21720 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21779
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
F I I K D + +V + +E + + +A N
Sbjct: 21780 PVFDGGME-IIGYIIEMCKTDLGDWHKVNAEACVKTRYTVT---DLQAGEEYKFRVSAIN 21835
Query: 262 RGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
G VT ++ AP+L ++ + +I L G+PTPT W
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ R +I T FS L + + R+D G+Y + +N G + F V V P
Sbjct: 21896 KPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPG 21953
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLF- 434
PP ++ S TL W+ P DGG ++ +Y+VE W + S K +F
Sbjct: 21954 PPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW--QVISEKCTRQIFK 22011
Query: 435 --DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
DL EG Y FR+ A + YG+ P P+
Sbjct: 22012 VNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22043
Score = 118 bits (283), Expect = 1e-25
Identities = 98/396 (24%), Positives = 161/396 (40%), Gaps = 14/396 (3%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + I +D ++L W P +DGGA + Y +E S W
Sbjct: 6694 PGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLS 6752
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + +Y FRV A N +G S + + V+ PPV + + +
Sbjct: 6753 ATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQ 6812
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IK 256
K E + G SP + + + E + I + L +++ ++G +
Sbjct: 6813 LKWEPPLKDGG--SPILGYIIERCE--EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYR 6868
Query: 257 CTATNRGGHAVTKARLC-LEAAPKLRYPRQ----YEDGLLYEINETIFLKTTIVGKPTPT 311
+A N+ G + L L A P ++DGL + I + G P PT
Sbjct: 6869 VSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPT 6928
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
W + T DR+++ ++ L I ++RSD+G Y ++ +N + + V V
Sbjct: 6929 ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 6988
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTN 430
A P P+ + SV L WEPP DDGG + Y+VE W K +
Sbjct: 6989 ARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLE 7048
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ DL++G EY F++ A + G P+ PV +
Sbjct: 7049 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 7084
Score = 118 bits (283), Expect = 1e-25
Identities = 104/406 (25%), Positives = 169/406 (41%), Gaps = 33/406 (8%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP+++ ++ + W P +GG+P+ GY +E GS W R + +
Sbjct: 9102 PGPPGKPKVLARTK----GSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPIT 9157
Query: 137 RPELVLTGLEPPH-----KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ L P KYQFR A+N G SE SD V+ D P +
Sbjct: 9158 KVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP-EVAGDPIFPPGPPSCPEV 9216
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE---STSVLLFHQIL 248
+D T + + + SP + + E ++ + + +T + +
Sbjct: 9217 KDKTK-SSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLK 9275
Query: 249 PSDEGEIKCTATNRGGHAV---TKARLC---LEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + A N G + T + ++ P++ +D L+ + I +
Sbjct: 9276 ELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA 9335
Query: 303 TIVGKPTPTIEWRHDG----------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I G+PTP W DG H I D ++E + SV+ I KRS G+Y
Sbjct: 9336 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA--ENSSVIIIPECKRSHTGKYS 9393
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
I AKN G+ TA V V P PP+++ V+ S L W+ P DDGG ++ Y++E
Sbjct: 9394 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 9453
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W K T + DL+ +Y FR++AE+ +G+ P
Sbjct: 9454 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPP 9499
Score = 117 bits (282), Expect = 2e-25
Identities = 105/409 (25%), Positives = 169/409 (41%), Gaps = 23/409 (5%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP P++ I D ++ + W DGG+ + Y VE WI+
Sbjct: 15156 GPPDPPKNPEVTTITKD----SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 15211
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKR 190
+ ++GL H+Y+FR+ A N G S S S TV P V
Sbjct: 15212 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTS 15271
Query: 191 LEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
++ N + + +G +D+++I + T + + L +Q
Sbjct: 15272 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQ--- 15328
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE-DGLLYEINE-----TIFLKTT 303
E +I+ A N G A P + E D L ++ T+ L
Sbjct: 15329 --EYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP 15386
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
I G+P P ++W D + D+ I +++L + + R D G+Y + +N G +
Sbjct: 15387 IKGRPDPEVKWARDHGESL--DKASIESASSYTLLIVGNVNRFDSGKYILTVENSSGSKS 15444
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
A V V P PP+++ V SVTL W+PP DGG K+ NYIVE + +
Sbjct: 15445 AFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV 15504
Query: 424 ITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI 471
T+ KT+ + L EG Y FR+ AE+ YG+ P+ + V+ R +
Sbjct: 15505 ATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL 15553
Score = 117 bits (282), Expect = 2e-25
Identities = 120/420 (28%), Positives = 182/420 (43%), Gaps = 38/420 (9%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
KP K A P PPG+P+ I + N++TL+W T+DGG+ + GY VE L
Sbjct: 15928 KPSKVSECYVARDPCDPPGRPEAIIVTR----NSVTLQWKKPTYDGGSKITGYIVEKKEL 15983
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG-HSNYSELSDVLT----VSS 177
W++ + ++ +TGL H+Y+FRV A N G S SE + +T V
Sbjct: 15984 PEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDP 16043
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
R S +P K V A E+ KV+ + G P PTI W K D E+ ++ R I + +
Sbjct: 16044 PRISMDPK--YKDTIVVHAGESFKVDADI--YGKPIPTIQWIKGDQELSNTARLEIKSTD 16099
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+ L + D G A N G + + L P E ++ I+
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV-----LDRPGPPEGPVV--ISGV 16152
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEY- 351
K T+ KP P + D I + R + + L K + EY
Sbjct: 16153 TAEKCTLAWKP-PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYT 16211
Query: 352 -QIQAKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKV 405
+I A N +GE + V P PD P+ VT S+ + WE PA DGG ++
Sbjct: 16212 FRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEI 16271
Query: 406 GNYIVEYY-RTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
Y++E + G W K + + + + LIE +Y+FR+ AE+ G+S PS S+
Sbjct: 16272 LGYVLEKRDKEGIRWTRCHKRLIG-ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSA 16330
Score = 117 bits (281), Expect = 3e-25
Identities = 98/400 (24%), Positives = 165/400 (41%), Gaps = 21/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP +I + + ++TL W+ DGG+ + GY +E S W+R V
Sbjct: 19486 PSPPTSLEITSVTKE----SMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVY 19541
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-VT 195
+ TGL +Y++RV A N G S SE S ++ PP K ++ T
Sbjct: 19542 DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKT 19601
Query: 196 ALENDKVEFHVTFSG---IPSPTIAWFKDD-----YEIFSSRRTAITTDESTSVLLFHQI 247
+ V+ F G I T+ + K D I S R T T T+ +
Sbjct: 19602 TITIAWVK--PLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFR 19659
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ S ++ + K R E P + L+ + + + G+
Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKER---EEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGR 19716
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P + W + T R + T + L I +A R+D G+Y + +N++ + +
Sbjct: 19717 PVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V V P PP N++V +S L W+ P +DGG V NY +E W+ +
Sbjct: 19775 VKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC 19834
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + +L EG+ Y FR+ E+ +G+ P+ V+I
Sbjct: 19835 NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 19874
Score = 116 bits (280), Expect = 3e-25
Identities = 99/385 (25%), Positives = 159/385 (41%), Gaps = 14/385 (3%)
Query: 91 DDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHK 150
D N+I L W P +DGG+ ++GY VE GS +W+ P+ ++ +TGLE
Sbjct: 7101 DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKW 7159
Query: 151 YQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSG 210
Y +RV LN G S S ++ + + + E + +K L +T K+E T +G
Sbjct: 7160 YAYRVKTLNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTG 7219
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W K D + +R I S + SD G A N G A A
Sbjct: 7220 KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT--A 7277
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI--E 328
+ + K P ++ + NE+ L + + TD + +
Sbjct: 7278 VVEVNVLDKPGPPAAFD--ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 7335
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-----PPDPPRNVSVT 383
+S T K + K + +++ A+N+ G +TA PP PP + +
Sbjct: 7336 LSSTVKDTNFKATKLIPNKEYIFRVAAENMYGAGEPVQASPITAKYQFDPPGPPTRLEPS 7395
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSE 441
+VTL W P DDGG + Y VE + W++ + + T + L +
Sbjct: 7396 DITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKK 7455
Query: 442 YKFRIKAESPYGMSAPSSESSPVRI 466
Y+FR+ AE+ G PS + P+ I
Sbjct: 7456 YRFRVLAENLAGPGKPSKSTEPILI 7480
Score = 116 bits (280), Expect = 3e-25
Identities = 107/397 (26%), Positives = 165/397 (41%), Gaps = 17/397 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K+A P+PPGK L+D + +L W HDGG+ + GY VE G+ +W A
Sbjct: 17711 KAAEPPSPPGKVT----LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 17766
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V V+TGL +YQFRV A N+ G S+ L V ++ D Q
Sbjct: 17767 ESKVC--NAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG-VPVIAKDLTIQPSLKLPFNT 17823
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ A E+ K+E V G P P I+W KD + + R + +++VL + D
Sbjct: 17824 YSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDD 17881
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ TATN G A + + P D + + + G
Sbjct: 17882 FGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTG-GCQI 17940
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE----DTAAFL 367
+ + T +S T + +KI K +++I A+N G+ D+ A +
Sbjct: 17941 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI 18000
Query: 368 VTVT-APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V P PP VT + + W P +DGG K+ Y +E +W+K +
Sbjct: 18001 VQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKT 18060
Query: 427 --RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T L EG EY+F++ AE+ G+ PS S
Sbjct: 18061 PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 18097
Score = 116 bits (279), Expect = 5e-25
Identities = 98/401 (24%), Positives = 170/401 (42%), Gaps = 23/401 (5%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVL 136
APPGKPQ P ++D +++L W+ +GG+ + GY +E ++ EW + P +
Sbjct: 23534 APPGKPQN-PRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23592
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R E LT L +Y+FRV A N G +E+ + V+ + + + E +
Sbjct: 23593 R-EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFV 23651
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ + + G P P W K+ +I S+R I T E+ + L+ + D G
Sbjct: 23652 RQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYD 23709
Query: 257 CTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
N+ G ++ + +P P +Y+D + + + + + +
Sbjct: 23710 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR--VSWRPPADDGGADILGYI 23767
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG------EDTAAFLVT 369
+ + I + + L + K + +++ A+N G + T
Sbjct: 23768 LERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 23827
Query: 370 VTAPPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
PP+PP N V K SV+L W P DDGG +V Y +E T + K + K
Sbjct: 23828 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD---KVVRHNK 23884
Query: 429 TNV-----TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + T+ L+ +EY+FRI A++ G+S S S PV
Sbjct: 23885 TQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 23925
Score = 115 bits (277), Expect = 8e-25
Identities = 110/423 (26%), Positives = 178/423 (42%), Gaps = 24/423 (5%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVLRPELVLTGL 145
PI+++ ++ + W HDGG P+ Y +E S W R T PI + + L
Sbjct: 10521 PIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDL 10579
Query: 146 EPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFH 205
+Y+FRV+A N++G + S S + A PPV + + D T D
Sbjct: 10580 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAI-DTTCNSVDLTWQP 10638
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVLLFHQILPSDEGE---IKCTATN 261
G S + + + ++ R A T ES + ++ +G+ + A N
Sbjct: 10639 PRHDG-GSKILGYIVEYQKVGDEEWRRANHTPESCPETKY-KVTGLRDGQTYKFRVLAVN 10696
Query: 262 RGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
G + V + L + P+L ++ +T+ L I G P P + W+
Sbjct: 10697 AAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWK 10756
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ T RI+ +TP S L+I +A D G Y + +N G T + V V P
Sbjct: 10757 KEDRDAPTKARID--VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG 10814
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLF 434
PPR++ V+ S L W+ P DDGG + NY+VE W + TS+K +
Sbjct: 10815 PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAK 10874
Query: 435 DLIEGSEYKFRIKAESPYGMS------APSSESSPVRIPGRAIDMDFLAVEARIINEALT 488
L EG++Y FR+ AE+ YG P P+ PG D+ + V+ ++
Sbjct: 10875 HLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 10934
Query: 489 RED 491
+ D
Sbjct: 10935 KPD 10937
Score = 115 bits (277), Expect = 8e-25
Identities = 102/402 (25%), Positives = 161/402 (40%), Gaps = 27/402 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P I + + ITLKW P DGG+ + GY +E R G+ W+R V
Sbjct: 21360 PPGTPDYIDVTRE----TITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSEC 21414
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI---KRLEDVT 195
+ +TGL P +Y+FR+ A N VG + S + ++ D PP+ + + +
Sbjct: 21415 QYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDE--NVPPIVEFGPEYFDGLI 21472
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P + WFKD EI IT ++ L G
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVY 21532
Query: 256 KCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
A N G A + ++ ++ P K+ P ++ + + T++ + P +
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTN--ITGEKMTLWWDAPLNDGCAPITHY 21590
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ--IQAKNIIG------EDTAAF 366
+ T I K + K + EYQ + A N G D
Sbjct: 21591 IIEKRE--TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVA 21648
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
+ T P D P + S+TL W P DGG ++ YI+E W+K I+
Sbjct: 21649 QIQYTVP-DAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 21707
Query: 427 RKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
R + T F L EG+EY+F + AE+ G+ S S ++
Sbjct: 21708 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIK 21749
Score = 113 bits (273), Expect = 2e-24
Identities = 107/411 (26%), Positives = 173/411 (42%), Gaps = 28/411 (6%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
K KN A P PPG P+ I + + N ITL+W +DGG+ + GY VE L
Sbjct: 17010 KASKNSECYVARDPCDPPGTPEPIMV----KRNEITLQWTKPVYDGGSMITGYIVEKRDL 17065
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRAS 181
W++ + V+ + ++GL +Y+FRV A N G S S+ + +T +
Sbjct: 17066 PDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 17125
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ K + + + G P PTI W + D EI S R I + ++
Sbjct: 17126 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL 17185
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ + D G+ A+N G + + L P E + ++ K
Sbjct: 17186 LIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV-----LDRPGPPEGPV--QVTGVTSEK 17238
Query: 302 TTIVGKPTPTIEWRHD-GHPII---TDDRIEISITPKFSV---LKIHSAKRSDRGEYQIQ 354
++ P P + D H ++ R+ ++ V LK+ + ++I
Sbjct: 17239 CSLTWSP-PLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 17297
Query: 355 AKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYI 409
A N +GE + V + P P PP+++ VT S+T+ W P DGG ++ YI
Sbjct: 17298 AVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 17357
Query: 410 VEYYRTGWNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPS 458
VE W+K R T++ L L E EY+FR+ AE+ G+ PS
Sbjct: 17358 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17408
Score = 113 bits (271), Expect = 4e-24
Identities = 101/384 (26%), Positives = 162/384 (42%), Gaps = 16/384 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I + + +A+ L W +DGGAP++ Y +E W+ R
Sbjct: 19781 PGPPTNITVQDVTKESAV-LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN-RLS 19838
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T L+ Y FRV+ N+ G +E + + ++ + E +D +L
Sbjct: 19839 YKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTW 19898
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
K E H S I + + + + A +T S L + E + A
Sbjct: 19899 LKPE-HDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLR-----ENSEYFFRVFA 19952
Query: 260 TNRGGHAVTKARLC-LEAAPKLRYP----RQYEDGLLY-EINETIFLKTTIVGKPTPTIE 313
N+ G + + L + +L P + + +Y + + I GKP P +
Sbjct: 19953 ENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVT 20012
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
DG P+ R IT + + + + +D G Y+I A N G A + V
Sbjct: 20013 LSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDR 20072
Query: 374 PDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNV 431
P PP V + ++SVTL WEPP DGG +V NYI+ T VW + + T +T +
Sbjct: 20073 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMM 20132
Query: 432 TLFDLIEGSEYKFRIKAESPYGMS 455
+ L G EY+FRIKAE+ +G+S
Sbjct: 20133 KVMKLTTGEEYQFRIKAENRFGIS 20156
Score = 112 bits (270), Expect = 6e-24
Identities = 111/415 (26%), Positives = 173/415 (41%), Gaps = 27/415 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPI---V 135
PG P P +S N++T+ W +DGG+P+ GY +E S W R PI
Sbjct: 9820 PGAPDK-PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 9878
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +TGL YQFRV A+N G S SD T + D + P F ++ D T
Sbjct: 9879 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPAT-ARDPIAPPGPPF-PKVTDWT 9936
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEG 253
D +E+ S + + Y+ D+ + L+ +
Sbjct: 9937 KSSAD-LEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFY 9994
Query: 254 EIKCTATNRGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ + +A N G VT + +P L+ D ++ I + + GK
Sbjct: 9995 KFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10054
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ W + + + IE + V+K + +RS +G Y + AKN GE +
Sbjct: 10055 PPPTVTWNMNERTLPQEATIETTAISSSMVIK--NCQRSHQGVYSLLAKNEAGERKKTII 10112
Query: 368 VTVTAPPDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AIT 425
V V P P + + ++S L W P DDGG + NY++E + W T
Sbjct: 10113 VDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYT 10172
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMS--APSSES----SPVRIPGRAIDMD 474
+ N T+ LI+G Y FRI AE+ GM +SE+ P+ +P R D++
Sbjct: 10173 VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 10227
Score = 110 bits (265), Expect = 2e-23
Identities = 96/403 (23%), Positives = 156/403 (38%), Gaps = 15/403 (3%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
V++K+ PG P I+ D N+ITL W +DGG+ + GY VE + EW
Sbjct: 17412 VYYKACDPVFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQ 17470
Query: 129 RTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF 187
P LR ++ L +Y+ RV ALN VG + + + + E +
Sbjct: 17471 IVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLD 17530
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ + + H+ F G P P I W +++ E + + I + + L
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPMPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNC 17588
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-NETIFL--KTTI 304
+D G+ N G ++ L P ++ + E+ ++ FL + I
Sbjct: 17589 DRNDAGKYILKLENSSG-----SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPI 17643
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT- 363
+ + D +S + K+ + +++ A+N G
Sbjct: 17644 IDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 17703
Query: 364 --AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
V PP PP V++T S +L WE P DGG +V Y+VE G W
Sbjct: 17704 VETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS 17763
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
S+ N + L G EY+FR+KA + G S P PV
Sbjct: 17764 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPV 17806
Score = 110 bits (265), Expect = 2e-23
Identities = 105/398 (26%), Positives = 165/398 (41%), Gaps = 26/398 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P+ I I N +TLKW +DGG+ + GY VE L W++ + VL
Sbjct: 18108 PPGRPEAIVITR----NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 18163
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL +Y+FRV A N G+ S S+ S +T + + + K + +
Sbjct: 18164 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18223
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G P P + W KD E+ ++ R I + + L+ + +D G+
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
+N GG TK+ + K+ +G L ++ K + P +
Sbjct: 18284 LKLSNVGG---TKS---IPITVKVLDRPGSPEGPL-KVTGVTAEKCYLAWNPPLQDGGAN 18336
Query: 317 DGHPIITD---DRIE-ISITPKFSVLKIHSAKRSDRGEY--QIQAKNI--IGEDTAAFLV 368
H II R+ ++ + L K EY ++ A N IGE + V
Sbjct: 18337 ISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPV 18396
Query: 369 TVT---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
T PP PP V+ S+ + W P DDGG ++ YI+E W K
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456
Query: 426 SRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ L L EG Y+FR+ AE+ G+ PS S
Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494
Score = 110 bits (264), Expect = 3e-23
Identities = 99/399 (24%), Positives = 159/399 (39%), Gaps = 26/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG+ ++ + N T+KW DGG+ + GY VE GS +W L
Sbjct: 18799 PLPPGRVTLVDVTR----NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTL 18854
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E ++GL +Y FRVAA+N+ G S+ +L V ++ D + +V A
Sbjct: 18855 --EATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDIEIKPSVELPFHTFNVKA 18911
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E K++ V F G P T+ W KD + + R +++ ++ + L + D G +
Sbjct: 18912 REQLKID--VPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE 18969
Query: 257 CTATNRGGHAVTKARLCLEAAP----KLRYPRQYEDGLLYEINETIF-----LKTTIVGK 307
+N G + + P +R D + N + + IV K
Sbjct: 18970 LCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEK 19029
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
T H + I+I S + + G K+ E +A
Sbjct: 19030 KETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYG------KSSYSESSAVVA 19083
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--IT 425
+PP PP V ++ + W+ P +DGG +V Y +EY +W KA I
Sbjct: 19084 EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKIL 19143
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T V + L EG Y++R+ AE+ G+ S PV
Sbjct: 19144 IADTQVKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19182
Score = 109 bits (263), Expect = 4e-23
Identities = 92/395 (23%), Positives = 166/395 (42%), Gaps = 17/395 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P +P+ + + + N +TL W P +DGG+ + Y +E +G+ ++ + +L +
Sbjct: 10220 PERPEDLEV-KEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10278
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ GL+ Y++RV+A+N VG S + +T + A P + + + +T
Sbjct: 10279 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAP--PTLHLDFRDKLTIRVG 10336
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
+ +SG P P ++WFKD+ ++ RT I T +T L + SD G+
Sbjct: 10337 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 10396
Query: 260 TNRGGH--AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHD 317
N G + + P + P +++ + + I K + + + +
Sbjct: 10397 ENSTGSRKGFCQVNVVDHPGPPVG-PVSFDE--VTKDYMVISWKPPLDDGGSKITNYIIE 10453
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP---- 373
+ D + ++ + K+ ++I A+N+ G ++ A
Sbjct: 10454 KKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFR 10513
Query: 374 -PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
PD P VT S + W P DGG + NYI+E T W + T
Sbjct: 10514 VPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYT 10572
Query: 433 LF---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
F DL+EG +Y+FR+ AE+ G+ PS S PV
Sbjct: 10573 KFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPV 10607
Score = 109 bits (263), Expect = 4e-23
Identities = 103/400 (25%), Positives = 170/400 (42%), Gaps = 26/400 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P++ I +++LKW+ +DGGA + GY VE L W++ +
Sbjct: 19190 PPGQPEVTNITR----KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQET 19245
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+T L +Y+FRV A N S SE + + V D + +K + +
Sbjct: 19246 YFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK 19305
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ ++ + +G P P I+W KD EI RT I + ++ ++L + D G+
Sbjct: 19306 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVL 19365
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV-GKPTPTIEWRH 316
T N V R L P L EIN K ++ G+P
Sbjct: 19366 TLKN-----VAGTRSVAVNCKVLDKPGPPAGPL--EINGLTAEKCSLSWGRPQEDGGADI 19418
Query: 317 DGHPIITDDRIEISITPKFSVLKIHSAKRSD--RG-EYQIQAKNI----IGEDTAAFLVT 369
D + + ++ T L++ S K + +G EY + + +GE + +
Sbjct: 19419 DYYHRKKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIK 19478
Query: 370 VTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
P P PP ++ +T +S+TL W P DGG ++ YI+E W++
Sbjct: 19479 ALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKK 19538
Query: 427 R--KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V L EG EY++R+ AE+ G+S P SE+SP+
Sbjct: 19539 PVYDLRVKSTGLREGCEYEYRVYAENAAGLSLP-SETSPL 19577
Score = 109 bits (262), Expect = 5e-23
Identities = 105/394 (26%), Positives = 164/394 (41%), Gaps = 32/394 (8%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++T+ W T DGGAP+ Y VE R + +T + ++GL + FR
Sbjct: 23055 DSVTITWEIPTIDGGAPINNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMHYFR 23113
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE--DVTALENDKVEFHVTFSGIP 212
V N G E SD + VS E P+ +LE DVT + G
Sbjct: 23114 VLPENIYGIGEPCETSDAVLVS------EVPLVPAKLEVVDVTKSTVTLAWEKPLYDG-G 23166
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IKCTATNRGG----- 264
S + + + + R + T + T +L H + +EGE + A N G
Sbjct: 23167 SRLTGYVLEACKAGTERWMKVVTLKPT--VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPR 23224
Query: 265 HAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
VT + L P + + + + L I G+P P W G +
Sbjct: 23225 ETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRE 23284
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+R+ + K + L I D GEY ++ KN+ G + V + P PP
Sbjct: 23285 SERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKI 23344
Query: 384 RQVD-KSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEG 439
++D S+T+ WEPP DGG + Y+VE +R GW +++T ++ L EG
Sbjct: 23345 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVT--RSTFKFTRLTEG 23402
Query: 440 SEYKFRIKAESPYGM-SAPSSE----SSPVRIPG 468
+EY FR+ A + +G+ S SE S +RIPG
Sbjct: 23403 NEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG 23436
Score = 108 bits (260), Expect = 9e-23
Identities = 87/403 (21%), Positives = 162/403 (40%), Gaps = 12/403 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI- 134
+P PP P++I I +++ L W+ +DGG ++GY VE + EW PP
Sbjct: 16340 KPGPPNNPKVIDITR----SSVFLSWSKPIYDGGCEIQGYIVEKCDVNVGEWTMCTPPTG 16395
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
+ + + + L H+Y FR+ A+N G ++++ + V + + + ++ + +
Sbjct: 16396 INKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 16455
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ V G P+P + W K D EI + +T+ S + L+ + D G+
Sbjct: 16456 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGK 16513
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
T N G A + + P + + + + +I + ++ + +
Sbjct: 16514 YTLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNY 16571
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVT 371
+ + + KI + +++ A+N G A + V
Sbjct: 16572 IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVA 16631
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV 431
P PP ++V SV+L W P DGG K+ YIVE W + +
Sbjct: 16632 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
+ +L +G EY FR+ A + G S P S + P+ I+ D
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPD 16734
Score = 108 bits (259), Expect = 1e-22
Identities = 98/399 (24%), Positives = 157/399 (39%), Gaps = 30/399 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECN-RLGSTE----WIR-TAP 132
PPG P ++ D ++ITL W +DGGAP+ GY VE ++ W R A
Sbjct: 11999 PPGPPTNFRVV-DTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12057
Query: 133 PIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 192
++R E +T L+ +Y+FRV A N VG +EL + + E + +
Sbjct: 12058 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRK 12117
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
V + G P+P + W K + R+ + ++ + L+ D
Sbjct: 12118 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV-VRKGQVDLVDTMAFLVIPNSTRDDS 12176
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ T N G + + L P D + ++ +T + P
Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV-----LDTPGPVSDLKVSDVTKT---SCHVSWAPPEND 12228
Query: 313 EWRHDGHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIGEDTAAF 366
H I+ D + ++TP+ H EY ++ A N G
Sbjct: 12229 GGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 12288
Query: 367 L---VTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--N 418
+ V + P PDPPR + T S TL W PP DGG K+ YI+ Y +
Sbjct: 12289 VPKPVLASDPLSEPDPPRKLEATEMTKNSATLAWLPPLRDGGAKIDGYIISYREEEQPAD 12348
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W + + ++ + L EG +YKFR+ A + G+S P
Sbjct: 12349 RWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLP 12387
Score = 107 bits (256), Expect = 3e-22
Identities = 90/402 (22%), Positives = 162/402 (40%), Gaps = 11/402 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIV 135
PAPP P++ D ++++L W +DGG+P+ GY VE R S W+R P +
Sbjct: 13092 PAPPAFPKVY----DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13147
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +YQFRV A+N +G+S+ S++ D E + +
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEHDADLRKTLI 13207
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ +V G P P I W K + + I + + + L + D G+
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
T N G + + ++ P + + + + + I+ +P I +
Sbjct: 13268 ILTLENSCGK--KEYTIVVKVLDTPGPPINVTVKEISKDSAYVTWEPPIIDGGSPIINYV 13325
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTA 372
++ + ++ + + +++ A+N G V +
Sbjct: 13326 VQKRDAERKSWSTVTTECSKTSFRVPNLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ 13385
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
P P ++ V S ++ W+ P DGG ++ Y+V++ T N W + + S +
Sbjct: 13386 TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSLSLQYS 13444
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
DL EG EY FR+ AE+ G PS + R A D+D
Sbjct: 13445 AKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLD 13486
Score = 107 bits (256), Expect = 3e-22
Identities = 102/405 (25%), Positives = 170/405 (41%), Gaps = 25/405 (6%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ P+PP I+ I + ++L W HDGG+ + GY +E R GS +W T
Sbjct: 14463 KASEAPSPPDSLNIMDITK----STVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW--TH 14516
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKR 190
V E V+ L +Y F+V A+N G S E V+ + + ++
Sbjct: 14517 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQK 14576
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L A +N KVE V G P PT+ W K D + ++R T ++++L ++ + S
Sbjct: 14577 LVIAKAGDNIKVEIPVL--GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 14634
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D G TA N G + + P P ++++ + + G P
Sbjct: 14635 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 14694
Query: 310 P--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED---TA 364
+E R + +E++ T + K +++++A+N G T+
Sbjct: 14695 SNYVVEMRQTD----STTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITS 14750
Query: 365 AFLVT--VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
A++V P PP VT S+T+ W P DGG + Y VE +W +
Sbjct: 14751 AWIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILW-Q 14809
Query: 423 AITSRKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++ +F L +G Y+FR+ AE+ G S PS S P+
Sbjct: 14810 TVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 14854
Score = 107 bits (256), Expect = 3e-22
Identities = 105/399 (26%), Positives = 160/399 (40%), Gaps = 21/399 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K A P PPGK + D N+++L W HDGG+ + Y VE S +W A
Sbjct: 16629 KVAEVPQPPGKITV----DDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16684
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V + V+T L +Y FRV A+N+ G S+ L+ V V+ D EP V
Sbjct: 16685 R--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA-VPIVAKDLVI-EPDVK-PAF 16739
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ ++ V SG P PTI W KD + + R +T + L + D
Sbjct: 16740 SSYSVQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 16799
Query: 252 EGEIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG-KPT 309
G+ T N G + L+ + P +++D I + G + T
Sbjct: 16800 GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQIT 16859
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
I + D + D +S T + LK+ K +++I A+N G+ A
Sbjct: 16860 NYIVQKRDTTTTVWD---VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP 16916
Query: 370 VTA-----PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ A P PP T S+ + W P ++GG V Y +E +W K
Sbjct: 16917 IVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 16976
Query: 425 TS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T +L EG EY+FR+ AE+ G+ S S
Sbjct: 16977 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17015
Score = 107 bits (256), Expect = 3e-22
Identities = 103/405 (25%), Positives = 172/405 (42%), Gaps = 24/405 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K +P+PP K + I D +++L W HDGG+ + Y VE G W++ A
Sbjct: 19873 KITEKPSPPEKLGVTSISKD----SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCA 19928
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ V++GL +Y FRV A N G S+ EL +L V + P + +K
Sbjct: 19929 --VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPREL--LLPVLIKEQLEPPEIDMKNF 19984
Query: 192 EDVTAL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR--TAITTDESTSVLLFHQI 247
T ++ + SG P P + +D + ++ R T IT + T + +
Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLT--INLKES 20042
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVG 306
+ +D G + TA N G TKA + + + P + E + T+ +
Sbjct: 20043 VTADAGRYEITAANSSG--TTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYD 20100
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--EDTA 364
+ + T E+S T +++K+ + +++I+A+N G +
Sbjct: 20101 GGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID 20160
Query: 365 AFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
+ VTV P P PP VT +S+T+ W P +GG V Y +E +W
Sbjct: 20161 SACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQ 20220
Query: 422 KA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
KA + R T+ + + G Y+FR+ AE+ G+ PS S PV
Sbjct: 20221 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPV 20265
Score = 106 bits (254), Expect = 5e-22
Identities = 97/398 (24%), Positives = 163/398 (40%), Gaps = 19/398 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
APPG P P ++D ++ L+W+P DGG+ + GY VE G EW + V
Sbjct: 9923 APPGPP--FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 9980
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+LV+TGL+ Y+FRV+A+N G E++DV+ + S + + + +
Sbjct: 9981 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVH 10040
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W ++ + + I T +S ++ S +G
Sbjct: 10041 AGGVIRIIAYVSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSL 10098
Query: 258 TATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEW 314
A N G + L+ + P + T F G P IE
Sbjct: 10099 LAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK 10158
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV- 368
R T + ++T + + + + ++I A+N IG E + A ++
Sbjct: 10159 RESDRRAWTP--VTYTVTRQNAT--VQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR- 427
P+ P ++ V +VTL W PP DGG ++ NY++E G + K
Sbjct: 10215 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 10274
Query: 428 -KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ L EG Y++R+ A + G PS + P+
Sbjct: 10275 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI 10312
Score = 104 bits (249), Expect = 2e-21
Identities = 99/403 (24%), Positives = 156/403 (38%), Gaps = 20/403 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + SD + L W DGG ++GY +E + W + P
Sbjct: 9415 PGPPKDLKV-SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCG-STT 9472
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR---LEDVTA 196
V+ L +Y FRV A N G E T +PP+ +K ++
Sbjct: 9473 FVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVH 9532
Query: 197 L--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L + K + + +AW + + R D ++ E E
Sbjct: 9533 LSWKPPKNDGGSPVTHYIVECLAWDPTGTKK-EAWRQCNKRDVEELQFTVEDLVEGGEYE 9591
Query: 255 IKCTATNRGGHAVTKARL--CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ A N G + A + C P + ++ + E + + I G P PT+
Sbjct: 9592 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 9651
Query: 313 EW------RHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
W + D P++ D + + L I ++RSD G Y I A N +G +
Sbjct: 9652 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9711
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ V P PP V +TL W PP DDGG K+ NY++E W+
Sbjct: 9712 MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVS 9771
Query: 425 TS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVR 465
+ ++ T+ L+EG EY FRI A++ YG+ P SE R
Sbjct: 9772 SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETAR 9814
Score = 103 bits (248), Expect = 3e-21
Identities = 84/391 (21%), Positives = 156/391 (39%), Gaps = 19/391 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P+++ + + + W +DGG+ + GY +E S W + ++
Sbjct: 19090 PGPPGTPKVVHATK----STMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIA 19145
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ ++GL+ Y++RV A N G S+ + + P +
Sbjct: 19146 DTQVKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVS 19205
Query: 197 LENDKVEFH--VTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH-QIL 248
L+ K + +G P W K +Y + + T E T + ++
Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYT--NIQETYFEVTELTEDQRYEFRVF 19263
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
+ + + G + K + P++ ++ D ++ + E + + I G+P
Sbjct: 19264 ARNAADSVSEPSESTGPIIVKDDV---EPPRVMMDVKFRDVIVVKAGEVLKINADIAGRP 19320
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P I W DG I R EI T ++L + R D G+Y + KN+ G + A
Sbjct: 19321 LPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC 19380
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITS 426
V P PP + + + +L W P +DGG + Y + T W +
Sbjct: 19381 KVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYHRKKRETSHLAWTICEGEL 19440
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ T+ + L++G+EY FR+ + YG+ P
Sbjct: 19441 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19471
Score = 103 bits (246), Expect = 5e-21
Identities = 95/398 (23%), Positives = 159/398 (39%), Gaps = 24/398 (6%)
Query: 77 PAPPGKPQIIPI-LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
P PPG PI D + TL W DGGA + Y VE W +
Sbjct: 21952 PGPPG-----PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW-QVISEKC 22005
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
R + L Y FRV+A+N+ G E+ + + + A PP +RL+ V
Sbjct: 22006 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA---PP---RRLDVVD 22059
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
++ V + I + + S +++ E E
Sbjct: 22060 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDLWVEAGHTKQLTFTVERLVEKTEYEF 22119
Query: 256 KCTATNRGGHAVTKARLC--LEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKP 308
+ A N G++ + + P++ P G+ ++ + I G+P
Sbjct: 22120 RVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGITNQLITCKAGSPFTIDVPISGRP 22178
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W+ + + DR+ I+ T + L + + R D G Y + +N G T + V
Sbjct: 22179 APKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTV 22238
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P P + V+ +S L W P D GG ++ NYIVE +G W +S
Sbjct: 22239 VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV 22298
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++T + + L + EY FR+ +E+ +G+S P ES+P+
Sbjct: 22299 KRTQIKVTHLTKYMEYSFRVSSENRFGVSKP-LESAPI 22335
Score = 101 bits (241), Expect = 2e-20
Identities = 118/429 (27%), Positives = 176/429 (41%), Gaps = 42/429 (9%)
Query: 65 PRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGS 124
P + + +A P P P I + N + L W P +DGG+P+ Y VEC
Sbjct: 9499 PVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 9558
Query: 125 T-----EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
T W + V + + L +Y+FRV A+N G S S + V R
Sbjct: 9559 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS--ATVGPCDCQR 9616
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYE--IFSSRRT 231
P + +K +V E V G+P PT+ WFK D+ E ++ +
Sbjct: 9617 PDMPPSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 9674
Query: 232 AITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGL 290
+ D+ T L+ Q SD G TA N G A + RL + P P ++E
Sbjct: 9675 KLVVDD-TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 9733
Query: 291 LYEINETIFLKTTIVG-KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
++ + F G K T + + + + + +S PK I
Sbjct: 9734 ADQMTLSWFPPKDDGGSKITNYVIEKREAN---RKTWVHVSSEPKECTYTIPKLLEGHEY 9790
Query: 350 EYQIQAKNI--IGE------DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDG 401
++I A+N IGE +TA L +V PD P SVTR S+T++WE P DG
Sbjct: 9791 VFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTR---NSMTVNWEEPEYDG 9847
Query: 402 GCKVGNYIVEYYRTGWNVW-------LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGM 454
G V Y +E T W +KA+T + + LIEGS+Y+FR+ A + G+
Sbjct: 9848 GSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT-LGVSYKVTGLIEGSDYQFRVYAINAAGV 9906
Query: 455 SAPSSESSP 463
S S P
Sbjct: 9907 GPASLPSDP 9915
Score = 101 bits (241), Expect = 2e-20
Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 18/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR--TAPPI 134
P P K +++ + + +TL W +DGG+ L GY +E + G+ W++ T P
Sbjct: 23138 PLVPAKLEVVDVTK----STVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 23193
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
VL E +T L +Y FR+ A N+ G S E +TV R + + +
Sbjct: 23194 VL--EHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 23251
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
VE + +G P P +WF ++ S R + T + L + D GE
Sbjct: 23252 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23311
Query: 255 IKCTATN-RGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
N G + T + L+ P + ++ + + TI + + P
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDE--IDATSITISWEPPELDGGAPLSG 23369
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
+ + + +S + S K + +++ A N IG + ++
Sbjct: 23370 YVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 23429
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITS 426
+ P PP + + +TL W PP DDGG +V YIVE + W++ +
Sbjct: 23430 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 23489
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T L EG EY+ R+ A + G PS S P+
Sbjct: 23490 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23527
Score = 97.5 bits (232), Expect = 2e-19
Identities = 102/414 (24%), Positives = 162/414 (39%), Gaps = 38/414 (9%)
Query: 64 KPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
KP + A RP P P I P L D L W DGG+P+ GY VEC + G
Sbjct: 11290 KPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPG 11349
Query: 124 STEWIRTAPPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ 182
+ +W R ++R + GL ++Y+FR+ A N VG EL++ +
Sbjct: 11350 TAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPP 11409
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E + + + +T + G P P I W K+ + +R + D L
Sbjct: 11410 EVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 11469
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +D G+ +A N GHA A + + P P Q LK
Sbjct: 11470 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPG---PCQN-------------LKV 11513
Query: 303 TIVGKPTPTIEWRH---DGHPIITDDRIEI--------SITPKFSVLKIHSAKRSDRGEY 351
T V K TI W + +G IT+ +E SI ++ A EY
Sbjct: 11514 TNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEY 11573
Query: 352 --QIQAKNIIG------EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++ A+N +G T + P P N+ + + V L W P DGG
Sbjct: 11574 YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGS 11633
Query: 404 KVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
+Y VE G + W + + ++T+ + +E Y+FR++ ++ G S
Sbjct: 11634 PNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGES 11687
Score = 96.3 bits (229), Expect = 5e-19
Identities = 100/405 (24%), Positives = 162/405 (40%), Gaps = 25/405 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P + SD +A+TL W DGG+P+ GY VE + +W+R V
Sbjct: 7385 PPGPPTRLEP-SDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 7443
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP--VFIKRLEDVTA 196
+ GL KY+FRV A N G S+ ++ + + PP +K + +
Sbjct: 7444 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSV 7503
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
N H + I S I K + + + T + L ++ E +
Sbjct: 7504 RLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH----LLPGLMEGQEYSFR 7559
Query: 257 CTATNRGGHAVTKAR----LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP--TP 310
A N+ G + LC E PR E ++ T LK T+ K +P
Sbjct: 7560 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE--VINITKNTADLKWTVPEKDGGSP 7617
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-------EDT 363
+ + + + T K + + +++ A+N IG ED+
Sbjct: 7618 ITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDS 7677
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
T T P PP ++V + V L WEPP +DGG + Y++E W+KA
Sbjct: 7678 VLAKDTFTTP-GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA 7736
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
N + D+IEG+E +F+++AE+ G+ PS + + I
Sbjct: 7737 GKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSI 7781
Score = 95.9 bits (228), Expect = 7e-19
Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 12/251 (4%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W +++ + + + ++ L I P D+GE + A ++ +A+L L
Sbjct: 6445 VQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEA----RAKLELA 6500
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAPK++ Q L+ ++ + + + P EW + P+ T I T +
Sbjct: 6501 AAPKIKTADQ---DLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQ 6554
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ +I AK+ D+G Y+I +N G+ + V P P RN+ VT D V+L WE
Sbjct: 6555 TSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWE 6614
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKAI-TSRKTNVTLFDLIEGS-EYKFRIKAESPYG 453
P DGG K+ Y+VE W+ A + T+ L +G EY FR+ A + G
Sbjct: 6615 EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVG 6674
Query: 454 MSAPSSESSPV 464
P +PV
Sbjct: 6675 TGEPVETDNPV 6685
Score = 94.7 bits (225), Expect = 2e-18
Identities = 99/394 (25%), Positives = 160/394 (40%), Gaps = 32/394 (8%)
Query: 99 LKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAAL 158
L W+ DGG+ + G+ +E W + P R + +TGL +Y+FRV A
Sbjct: 8718 LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 159 NDVGHSNYSELSDVLTVS--SDRASQEPPVFIKRLEDVTALE--NDKVEFHVTFSGIPSP 214
N G E+ +L V S E + +R L+ + G
Sbjct: 8776 NKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERQRSTITLDWKEPRSNGGSPIQGYIIE 8835
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
K D+E + +R TT L HQ+ E + A N G + L +
Sbjct: 8836 KRRHDKPDFERVN-KRLCPTTSFLVENLDEHQMY-----EFRVKAVNEIGESEPSLPLNV 8889
Query: 275 -----EAAPKLRYPRQYE-DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII--TD-- 324
E P ++ D + + E + + + G P P IEW + I TD
Sbjct: 8890 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 8949
Query: 325 --DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ E+S + + L I A R D+G Y + A N +G V V P PPRN++V
Sbjct: 8950 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAV 9009
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWN--VWLKAI-TSRKTNVTLFDLIEG 439
T +S L W+ P D+GG ++ +Y+++ W + T+ + ++ LI
Sbjct: 9010 TDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPN 9069
Query: 440 SEYKFRIKAESPYGMSAPSSE-----SSPVRIPG 468
+Y+FR++A + YG+S P R+PG
Sbjct: 9070 GQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPG 9103
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 7/182 (3%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
I + L+ GKP P+I W DG P+ + + S T L I +AK+ G+Y +
Sbjct: 21080 IGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV 21139
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N + V PP P+ + SV L W+ P D+GG ++ Y +E
Sbjct: 21140 ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEK 21199
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV-----RI 466
T W +S +T + +L++ +EY+FR++AE+ YG+S P S V RI
Sbjct: 21200 RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRI 21259
Query: 467 PG 468
PG
Sbjct: 21260 PG 21261
Score = 90.6 bits (215), Expect = 3e-17
Identities = 107/409 (26%), Positives = 169/409 (41%), Gaps = 50/409 (12%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLT--GLEP 147
SD ++ L W P DGG P+ Y +E G +I P + +L T L P
Sbjct: 7992 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYI---PVMSGENKLSWTVKDLIP 8048
Query: 148 PHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVT 207
+Y FRV A+N VG Y EL + + + +PPV ++ + + TA E + +
Sbjct: 8049 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE-VHNPTA-EAMTITWKPP 8106
Query: 208 FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG---EIKCTATNRGG 264
S + + + +I +E +L + +EG + + A N G
Sbjct: 8107 LYDGGSKIMGYIIE--KIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 8164
Query: 265 HAV-TKARLCLEAAPKLRYPRQY-EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH--- 319
+ ++A +A + P+ L + + I L +I G P PTI W D +
Sbjct: 8165 ISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224
Query: 320 ---------PIITDDRIEIS--------ITPKFSV---------LKIHSAKRSDRGEYQI 353
P++ + E+ +T + S+ L++ + R D G Y I
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY 413
+ +N G A V+V P PP N SV WEPP DDGG ++ NY +E
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 8344
Query: 414 -----RTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ W V + K +VT LIEG EY FR++AE+ +G P
Sbjct: 8345 DKTKPDSEWIVVTSTLRHCKYSVT--KLIEGKEYLFRVRAENRFGPGPP 8391
Score = 89.4 bits (212), Expect = 6e-17
Identities = 62/218 (28%), Positives = 99/218 (45%), Gaps = 16/218 (7%)
Query: 74 AGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAP 132
AG P PPG P P + D ++I+L W P DGG+P++GY VE G+T+W R
Sbjct: 9201 AGDPIFPPGPPSC-PEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNE 9259
Query: 133 P--IVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK- 189
P ++ E V+ L+ KY+FRV A+N+ G S S+ + + + +EP VFI
Sbjct: 9260 PDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATD--IQEEPEVFIDI 9317
Query: 190 -RLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTDESTS 240
+ + ++ G P+P +W D D + T E++S
Sbjct: 9318 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 9377
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
V++ + S G+ TA N+ G R+ + P
Sbjct: 9378 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVP 9415
Score = 88.6 bits (210), Expect = 1e-16
Identities = 92/410 (22%), Positives = 168/410 (40%), Gaps = 33/410 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+ + ++ + + ITL W +GG+P++GY +E R ++ R +
Sbjct: 8797 PPTSPERLTY-TERQRSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 8855
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL----EDV 194
++ L+ Y+FRV A+N++G S S +V+ + D + PP RL + +
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVV-IQDD---EVPPTIKLRLSVRGDTI 8911
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEI------FSSRRTAITTDESTSVLLFHQIL 248
+ V +G+P P I W K++ I + ++ E+ + L + +
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
D+G TA+NR G +E + PR + + + +
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVH--VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 9029
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA-KRSDRGEYQIQAKNI----IGEDT 363
+ + D + + E +V K + K G+Y+ + + + I ++
Sbjct: 9030 SEITHYVIDKRD-ASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 9088
Query: 364 AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ V + P P PP V + S+ + W PP D+GG + Y +E G W
Sbjct: 9089 KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYW 9148
Query: 421 LKAITSRKTNVTL----FD---LIEGSEYKFRIKAESPYGMSAPSSESSP 463
+ + T V L F+ L+EG +Y+FR A + G+ PS S P
Sbjct: 9149 SRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9198
Score = 87.0 bits (206), Expect = 3e-16
Identities = 92/404 (22%), Positives = 164/404 (40%), Gaps = 35/404 (8%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE---CNRLGSTEWIRTAPPIVL 136
PG+P++ +D + ++L W+ +DGG+ + GY +E + +G W++ IV
Sbjct: 22445 PGRPEV----TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22500
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+T L Y+FRV A N G S SE + +T + A + + + D V
Sbjct: 22501 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22560
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI--TTDESTSVLLFHQILPSDE 252
T + G P P I W K D E+ + ++ T +T+V+ F SD
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCD--RSDS 22618
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAP----KLRYPRQYED------GLLYEINETIFLKT 302
G+ T N G + + +P KL R ++ L E
Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678
Query: 303 TIVGKPTPTIEWRH-DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + T + W +G + I + ++ + + G ++++ I+
Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG-VPVESEPIVAR 22737
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV---EYYRTGWN 418
++ T+ +PP P V ++ + + W P DGG ++ NY+V E W
Sbjct: 22738 NS----FTIPSPPGIPEEVGTGKE---HIIIQWTKPESDGGNEISNYLVDKREKESLRWT 22790
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
K T + + L+EG +Y+FR+ A + G S PS S+
Sbjct: 22791 RVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSN 22834
Score = 86.6 bits (205), Expect = 4e-16
Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 298 IFLKTTIVGKPTPTIEWRHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
I L + G+P P + WR G ++ ++++ T F V I ++ R D G+Y +
Sbjct: 12127 IRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLV--IPNSTRDDSGKYSLTLV 12184
Query: 357 NIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG 416
N GE V V P P ++ V+ S + W PP +DGG +V +YIVE
Sbjct: 12185 NPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 12244
Query: 417 WNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
W +KT+ + +L+ G+EY FR+ A + YG P+ PV
Sbjct: 12245 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV 12293
Score = 83.8 bits (198), Expect = 3e-15
Identities = 80/313 (25%), Positives = 139/313 (44%), Gaps = 24/313 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P P + D ++++L W+ DGG+ + GY +E + + +R +
Sbjct: 23831 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNKTQITTT 23890
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRL-EDVT 195
+TGL P +YQFR+ A NDVG S S S+ + D+ SQ + I + +D
Sbjct: 23891 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 23950
Query: 196 ALENDKVE---------FHVTFSGIPSPTIAWFKDDYEIFSSRRTAI-TTDESTSVLLFH 245
L+ +K E + V + S AW K + E ++ I E+T +
Sbjct: 23951 TLQWEKPECDGGKEILGYWVEYR--QSGDSAWKKSNKERIKDKQFTIGGLLEATE----Y 24004
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ E E + R ++ K +L AP +R ++ +D + ++ E L IV
Sbjct: 24005 EFRVFAENETGLSRPRRTAMSI-KTKLTSGEAPGIR--KEMKD-VTTKLGEAAQLSCQIV 24060
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-DTA 364
G+P P I+W G +I + ++S + L + + ++ D G Y A N +GE +T+
Sbjct: 24061 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120
Query: 365 AFLVTVTAPPDPP 377
+ L+ P P
Sbjct: 24121 SKLLLQATPQFHP 24133
Score = 76.6 bits (180), Expect = 5e-13
Identities = 94/401 (23%), Positives = 158/401 (39%), Gaps = 33/401 (8%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+ D ++ L W DGG+ + Y VE G W I E+ ++ L+
Sbjct: 20974 MKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQ 21031
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
+FRV A N+ G S+ + + TV + E + VT V + +
Sbjct: 21032 SVLEFRVFAKNEKGLSDPVTIGPI-TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPY 21090
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN---RGGH 265
G P P+I+W KD + S + E+ L G+ N R
Sbjct: 21091 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAV 21150
Query: 266 AVTKARLCLEAAPK--LRYPRQYEDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPII 322
+T L + PK +R+ D ++ + + G+ T +IE R
Sbjct: 21151 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQ--- 21204
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPP 377
T+ ++ S + + K+ + + +++++A+N G + A P PP
Sbjct: 21205 TNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP 21263
Query: 378 RNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTL 433
+ ++L W+ P DGG +V + VE +W K TS R+ T
Sbjct: 21264 GKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRAT- 21322
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPSSES------SPVRIPG 468
L+EG +Y+FR+ AE+ G+S+PS S SPV PG
Sbjct: 21323 -GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG 21362
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/203 (24%), Positives = 81/203 (39%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 73.3 bits (172), Expect = 4e-12
Identities = 48/191 (25%), Positives = 80/191 (41%), Gaps = 10/191 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+PAPP + ++ D ++ L W HDGG+ + GY +E + GS W+
Sbjct: 22048 QPAPPRRLDVV----DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDLWVEAGHTKQ 22103
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-- 193
L + L +Y+FRV A ND G+S E + + + EP + + +
Sbjct: 22104 L--TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQI--EPTADLTGITNQL 22159
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T V SG P+P + W ++ + + R +ITT + + L + D G
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219
Query: 254 EIKCTATNRGG 264
T N G
Sbjct: 22220 RYFLTLENTAG 22230
Score = 72.1 bits (169), Expect = 1e-11
Identities = 59/208 (28%), Positives = 79/208 (37%), Gaps = 8/208 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS-RRTAITTDESTSVLL 243
PVF+ + LE F + G P P WF D +I + + ++ T L+
Sbjct: 1411 PVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
PSD GE A NR G + L +EA P E I E + +K
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMK 1530
Query: 302 TTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
G P P I W + I+ +I I T + LKI S D Y A N
Sbjct: 1531 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1590
Query: 360 GEDTAAFLVTVT---APPDPPRNVSVTR 384
G DT V V A P+P R + + R
Sbjct: 1591 GRDTTRCKVNVEVEFAEPEPERKLIIPR 1618
Score = 70.9 bits (166), Expect = 2e-11
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP + D ++ L W HDGGA + Y +E + G+ EW+R A +
Sbjct: 7487 PWPPGKPTV----KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT 7542
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
L L GL +Y FRV A+N G S SE SD + PP +++
Sbjct: 7543 TQHL-LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594
Score = 69.7 bits (163), Expect = 5e-11
Identities = 42/123 (34%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
APP PP VT S L+W PP DGG KV YIVEY G W K R T
Sbjct: 9923 APPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTR 489
+ + L EG+ YKFR+ A + G+ P + + + R + D L ++A + + +
Sbjct: 9982 KLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPD-LQLDASVRDRIVVH 10040
Query: 490 EDG 492
G
Sbjct: 10041 AGG 10043
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/94 (31%), Positives = 47/94 (50%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + L++VT +E + V SG PSPT+ W+++DY+I SS IT + L+
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G C+A N G T L ++ +
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 68.9 bits (161), Expect = 9e-11
Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 4/146 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P + + + A+T+ W P +DGG+ + GY +E G W R +V
Sbjct: 8079 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP 8138
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
GLE +YQFRV A N G S S + T + D P V ++ +V
Sbjct: 8139 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP-TKAVD-PIDAPKVILRTSLEVK- 8195
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDD 222
D++ + SG P PTI W KD+
Sbjct: 8196 -RGDEIALDASISGSPYPTITWIKDE 8220
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 351 YQIQAKNIIGEDT---AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
+++ A+N G + +V + +P P P ++T S + W+PPA DGG K
Sbjct: 24299 FRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAK 24358
Query: 405 VGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
+ NY +E N W+ T R+T ++ +LIEG EY+FR+K E+ G S S S
Sbjct: 24359 IRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE 24418
Query: 463 PV 464
P+
Sbjct: 24419 PI 24420
Score = 66.9 bits (156), Expect = 4e-10
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 12/193 (6%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI---FSSRRTAITT 235
R + PP F L + TA + V F VT + P P + W+K +I + ++ +
Sbjct: 25187 RLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFES 25246
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-----KLR--YPRQYED 288
D+ L + + D+ E A N+ G KA+L + P LR + R +
Sbjct: 25247 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 25306
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSD 347
E +++ + + G P PT++W DG P+ IEI + L I D
Sbjct: 25307 AECQE-GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 25365
Query: 348 RGEYQIQAKNIIG 360
G Y++ A N G
Sbjct: 25366 TGYYRVTATNTAG 25378
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT--SRKT 429
APP P+N VT SV+L W P D+GG KV Y++E + + W K T ++
Sbjct: 23534 APPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 23593
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
TL L +G+EY+FR+ A + G P+ V++
Sbjct: 23594 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23630
Score = 63.3 bits (147), Expect = 5e-09
Identities = 52/231 (22%), Positives = 97/231 (41%), Gaps = 10/231 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
W + + ++++ HK + + L+D+ +++ ++ + + + + P
Sbjct: 5109 WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK-AQVKELSSTAQLKVLEADPY 5167
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F +L D TA+E D++ S + WFKD EI S + +I D +L +
Sbjct: 5168 FTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKK 5225
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
D+GE C G TKA + +EA +L + G+ + ET + +
Sbjct: 5226 ADLKDKGEYVCDC----GTDKTKANVTVEA--RLIEVEKPLYGVEVFVGETAHFEIEL-S 5278
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+P +W+ G P+ EI K +L +H+ + GE QA N
Sbjct: 5279 EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAAN 5329
Score = 62.9 bits (146), Expect = 6e-09
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 6/179 (3%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W + E+ +S S L Q DEG + C + + G + K + L
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVKCQYDLT 26628
Query: 276 AAPKLR-YPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ +L P INE + I G+P+P IEW + PI + IS +
Sbjct: 26629 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 26688
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPDPPRNVSVTRQVDKSV 390
L+I +A SD G+Y I+AKN G+ +A A L+ + +P R V + D S+
Sbjct: 26689 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 26747
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPNPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 3517 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 3574
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCA 3660
Score = 62.5 bits (145), Expect = 8e-09
Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Query: 350 EYQIQAKNIIGEDTAAFL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
EY++ A+NI G + V P DPP VT KSV+L W P DGG K+
Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 19220
Query: 407 NYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPY-GMSAPSSESSP 463
YIVE WLK ++T + +L E Y+FR+ A + +S PS + P
Sbjct: 19221 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 19280
Query: 464 V 464
+
Sbjct: 19281 I 19281
Score = 61.3 bits (142), Expect = 2e-08
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 13/218 (5%)
Query: 164 SNYSELSDVLTVSSDRAS-----QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
S+ S +V TV A ++ P+ L D + E D V H+T S + + W
Sbjct: 4217 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV--HLTTSITNAKEVNW 4274
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEIKCTATNRGGHAVTKARLCL--E 275
+ ++ + S + D++T L+ ++ D +GE C A N G T A+L +
Sbjct: 4275 YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 4334
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAP ++ R+ E L + I P +W G I D+ I +
Sbjct: 4335 AAPVIK--RKIEP-LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4391
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
S L+I + D GEY +A N G + +TVT P
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 10/216 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F +L+D T +E D+V S +P + WFKD EI S+ I TD +L+
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKTDGKKRMLIL 5579
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ L SD G+ C G T +L +E +++ R + E ET +T I
Sbjct: 5580 KKALKSDIGQYTCDC----GTDKTSGKLDIEDR-EIKLVRPLHSVEVME-TETARFETEI 5633
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
+ W+ G ++ EI K L +H+ + G QA N+
Sbjct: 5634 -SEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHL 5692
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
V P ++V+VT ++ T D E +D
Sbjct: 5693 RVKPRVIGLLRPLKDVTVT--AGETATFDCELSYED 5726
Score = 59.7 bits (138), Expect = 6e-08
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
PP PP V + S++L W+PPA DGG + YIVE G W + K T
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266
Query: 433 ----LFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +L E +Y+FR+KA + G S PS + +
Sbjct: 9267 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 9302
Score = 59.3 bits (137), Expect = 7e-08
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 350 EYQIQAKNIIG-----EDTAAFLVT-VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++Q++A+N G E T + T+PP PP ++ VT K + + W+PP +GG
Sbjct: 7758 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 7817
Query: 404 KVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEG----SEYKFRIKAESPYGMSAPSS 459
+ Y VE G W++ + SR F + EG EY R++A + G+S PS
Sbjct: 7818 PIIGYHVEMCPVGTEKWMR-VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSE 7876
Query: 460 ESSPV 464
S V
Sbjct: 7877 ISENV 7881
Score = 58.8 bits (136), Expect = 1e-07
Identities = 71/327 (21%), Positives = 135/327 (41%), Gaps = 28/327 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE------PPVFIKRLEDVTALENDKVE 203
KY+ + + D G + E ++T D++ E P F++ LED T E D
Sbjct: 6288 KYK-HMLTIKDCGFPDEGEY--IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAV 6344
Query: 204 FHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG 263
F S + W+++ EI ++ D S L+ DE E C +R
Sbjct: 6345 FSCQLSR-EKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 6403
Query: 264 GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
++ARL +E P + R +D L + +FL + K ++W + ++
Sbjct: 6404 ----SRARLFVEEIP-VEIIRPPQDILEAPGADVVFLAE--LNKDKVEVQWLRNNMVVVQ 6456
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
D+ ++ K L+I K D+GEY+ AK+ ++ A L AP + +
Sbjct: 6457 GDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD---KEARAKLELAAAPKIKTADQDLV 6513
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSE 441
V K +T+ P D E+++ + K I T+ +T+ + + +G +
Sbjct: 6514 VDVGKPLTM--VVPYD----AYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDK 6567
Query: 442 YKFRIKAESPYGMSAPSSESSPVRIPG 468
+++I ++ +G + + +PG
Sbjct: 6568 GRYKIVLQNKHGKAEGFINLKVIDVPG 6594
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/116 (32%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTN 430
P PP N V SV L W P DGGC++ YIVE W + KTN
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVNVGEWTMCTPPTGINKTN 16400
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR--AIDMDFLAVEARIIN 484
+ + L+E EY FRI A + G+ + P+ + + A D+D +IIN
Sbjct: 16401 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 16456
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKT 429
PP PP + + S+TL W P DGG V Y+VE + W T R T
Sbjct: 20669 PPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTT 20728
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR----IPGRAIDMDFLAVEARIINE 485
+ +L G Y FR+ A + G P + PV+ + ID+D +A+ +I +
Sbjct: 20729 EYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLD-VALRTSVIAK 20787
Query: 486 A 486
A
Sbjct: 20788 A 20788
Score = 57.2 bits (132), Expect = 3e-07
Identities = 47/201 (23%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 3310 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3369
Query: 353 IQAKNIIGEDTAAFLVTVTAP 373
A N +G+ ++ +++ AP
Sbjct: 3370 FVANNAVGQVSSTANLSLEAP 3390
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P P++ + ++ +T+ W P +DGG + GY +E ST W+ +
Sbjct: 11898 KPGRPDPPEVTKVSKEE----MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAI 11953
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVG 162
+ + L P H+YQFRV A N++G
Sbjct: 11954 PERRMKVQNLLPDHEYQFRVKAENEIG 11980
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW-NVWLKAITSRKT 429
PDPP VT+ + +T+ W PP DGG + Y +E + T W V AI R+
Sbjct: 11902 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 11958
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V +L+ EY+FR+KAE+ G+ PS S PV
Sbjct: 11959 KVQ--NLLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/110 (34%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P I + + +IT+ W P DGGAPL GY VE W+ + V
Sbjct: 23334 KPGPPTGPIKI---DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-V 23389
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
R T L ++Y FRVAA N G +Y + S+V+ S PP
Sbjct: 23390 TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQ-SEVIECRSSIRIPGPP 23438
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA-ITTDEST 239
S E P +R++ T + F V G P P W+K+ +I S R +++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ + D I A N G + A L ++A + + ++ +D + E +T+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE-KDTMA 2146
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+P ++W DG + D+ + K L I + SD +Y
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2198
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF EI S + + +
Sbjct: 2740 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2798
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 2799 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 2850
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 2851 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 2907
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 2908 --VCGNDQVSATLTVT 2921
Score = 55.2 bits (127), Expect = 1e-06
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ LED T E + F S + WFK+D ++ +SR I+++ T L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE 5137
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +IK A K LEA P + + D E +E I LK V
Sbjct: 5138 VTLDDISQIKAQVKELSSTAQLKV---LEADPY--FTVKLHDKTAVEKDE-ITLKCE-VS 5190
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K P ++W DG I+ + I +LKI A D+GEY
Sbjct: 5191 KDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 5234
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEP----PVFIKRLEDVTALENDKVEFHVTFS 209
+V+ +++ S+ +T ++ + EP PV + L+D T + +F V +
Sbjct: 26320 KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT 26379
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P PT W KD I + ++ D+ L H+ SD G CT N G +
Sbjct: 26380 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26439
Query: 270 ARLCLEA 276
+L ++A
Sbjct: 26440 CKLTIKA 26446
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFH 245
F R+++ LE V FH SG P P IAW+KD I R + + + L
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+LP DEG A+N G+A+ +L +E A L P
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAP 1344
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTN 430
PP P V ++++ WE P DGG K+ Y VE +W+K + + N
Sbjct: 22343 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECN 22402
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG EY+FR A + G+S S S P+
Sbjct: 22403 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 22436
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 2922 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 2978
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 2979 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 3031
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 3085
Score = 53.6 bits (123), Expect = 4e-06
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTS 240
P F+K ++D+ E++ V F + SP+ A W KD I S + D
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 4676
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + SD GE C + A+L +E P +R+ + E+ + + ++L
Sbjct: 4677 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP-VRFVKTLEEEVTVVKGQPLYL 4735
Query: 301 KTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ + WR DG ++ RI + L I+ A +D G Y + +N
Sbjct: 4736 SCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 4791
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 10/164 (6%)
Query: 338 LKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVTAPP----DPPRNVSVTRQVDKSVT 391
L++ E+++ A+N +GE + A + P PP N + S+T
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 17440
Query: 392 LDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD---LIEGSEYKFRIKA 448
L W P DGG ++ Y+VE + W VT F+ L E EYK R+ A
Sbjct: 17441 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17500
Query: 449 ESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDG 492
+ G+ +S V+ P ++ L +++ + + R G
Sbjct: 17501 LNKVGLGEATSVPGTVK-PEDKLEAPELDLDSELRKGIVVRAGG 17543
Score = 52.8 bits (121), Expect = 6e-06
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 4/148 (2%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+L + + ++ V A N G + V S P+F + L + E
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 25311
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQILPSDEGEIKC 257
V F + SGIP PT+ W KD + I + L LP D G +
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQ 285
TATN G +A L +E +LRY +Q
Sbjct: 25372 TATNTAGSTSCQAHLQVE---RLRYKKQ 25396
Score = 52.4 bits (120), Expect = 8e-06
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L++ P ++ V A N G S+ +S +LTV + Q P+F+++L++V E
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSS---ISVILTVEAVE-HQVKPMFVEKLKNVNIKEG 1524
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVLLFHQILPSDEGEIKC 257
++E V +G P+P I W K+ I + + I + + L + D
Sbjct: 1525 SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1584
Query: 258 TATNRGGHAVTKARLCLE 275
TA N+ G T+ ++ +E
Sbjct: 1585 TAINKAGRDTTRCKVNVE 1602
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY--------RTGWNVWLKAI 424
PP PP N V S+TL W P DGG + Y+VE GW A
Sbjct: 11999 PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAA 12058
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ T+ L E EY+FR+ A++ G+ P+ ++
Sbjct: 12059 QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 12099
Score = 50.8 bits (116), Expect = 3e-05
Identities = 44/189 (23%), Positives = 79/189 (41%), Gaps = 12/189 (6%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+E VF K L ++ E D ++ S P + W+K D EI + R I T+ +
Sbjct: 5963 EEEAVFTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRI 6021
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ D G C + K ++ AA + P+ E + E + F+
Sbjct: 6022 LVIQNAHLEDAGNYNCRLPS--SRTDGKVKVHELAAEFISKPQNLE---ILEGEKAEFVC 6076
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + K + ++W+ D + + D+ ++ K VL + A D G Y + ++G
Sbjct: 6077 S--ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVV----MVGA 6130
Query: 362 DTAAFLVTV 370
AA +TV
Sbjct: 6131 ARAAAHLTV 6139
Score = 49.2 bits (112), Expect = 8e-05
Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 5/149 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 3310 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3368
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPR 284
A N G + A L LEA + + R
Sbjct: 3369 TFVANNAVGQVSSTANLSLEAPESILHER 3397
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P PT+ W G + T R +++ T S +I S + SD G Y + +N G+ A
Sbjct: 26089 GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAE 26148
Query: 366 FLVTV 370
F +T+
Sbjct: 26149 FTLTI 26153
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ L+DVTA E + F V S + + WFK+D + ++R ++ + T + F
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELSH-DNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 5492
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +I+ A A LE P + + +D E +E I +
Sbjct: 5493 LSIDDTSQIRVEAMGMSSEAKLTV---LEGDP--YFTGKLQDYTGVEKDEVIL--QCEIS 5545
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K ++W DG I I K +L + A +SD G+Y
Sbjct: 5546 KADAPVKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSDIGQY 5590
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 3552 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 3611
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 3612 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3663
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K RP PP P + ++ ++ L W P DGGA + Y V+ W A
Sbjct: 15053 KVLDRPGPPEGPLAVTEVTSEK---CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 15109
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVS 176
+ + +L +T L ++Y FRV A+N G E VL V+
Sbjct: 15110 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN 15153
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A +N K + GRP PP P +S D+ +TL W P DGG+ + Y
Sbjct: 9700 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ---MTLSWFPPKDDGGSKITNYV 9756
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+E W+ + + L H+Y FR+ A N G
Sbjct: 9757 IEKREANRKTWVHVSSE-PKECTYTIPKLLEGHEYVFRIMAQNKYG 9801
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/186 (22%), Positives = 70/186 (37%), Gaps = 8/186 (4%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L+D E +V F+ + WF+++ IF S + I + L
Sbjct: 6149 LKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D+ + TN G V A + LR +D E F V +
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCK--VNRLNV 6265
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVT 369
T++W +G + D+R+ + +L I D GEY + A G+D + A L+
Sbjct: 6266 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAELLI 6321
Query: 370 VTAPPD 375
+ AP +
Sbjct: 6322 IEAPTE 6327
Score = 44.0 bits (99), Expect = 0.003
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPS 213
+ DV + E S V+ T + P ++ L D E D V+ V S + S
Sbjct: 2279 VKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LES 2337
Query: 214 PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC 273
W KD E+ S R I D+ + +LL + D G T G T R+
Sbjct: 2338 VEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALG--LSTSGRVS 2395
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+ + + +D + E + + L+ + +++W + I DDR++ +
Sbjct: 2396 VYSVDVI---TPLKDVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2451
Query: 334 KFSVLKIHSAKRSDRGEYQI 353
L I+ SD G Y++
Sbjct: 2452 TKQRLVINRTHASDEGPYKL 2471
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/176 (24%), Positives = 65/176 (36%), Gaps = 9/176 (5%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EPPV F K LED T E S + + WFK+ EI S++ I D
Sbjct: 5784 KEPPVEFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADGRVR 5842
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L+ H P D C A + T L + P + + R D + E F
Sbjct: 5843 KLVIHDCTPEDIKTYTCDAKD----FKTSCNLNV-VPPHVEFLRPLTDLQVREKEMARF- 5896
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
+ + ++W DG I + +I +L I+ D EY + +
Sbjct: 5897 -ECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVR 5951
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A+++A +N+ +P PP P +S D + + W P + GG + Y
Sbjct: 17888 TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYI 17944
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHS 164
VE +T W V R + +T L+ +YQFR+ A N G S
Sbjct: 17945 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 17991
Score = 43.6 bits (98), Expect = 0.004
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 6/146 (4%)
Query: 169 LSDVLTVSSDRASQEP--PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF 226
++D EP P FI + +E V F G P P + W K +
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1077
Query: 227 SSRRTAITTDESTS--VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ R ++ ++ T L+ D GE N+ G A L EA +L
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1137
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTP 310
Q E +LY+ T F++ VG+ P
Sbjct: 1138 QQE--MLYQTQVTAFVQEPEVGETAP 1161
Score = 43.6 bits (98), Expect = 0.004
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 66 RKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST 125
+K V A P PP ++ SD +++ L W DGG+ + Y VE +
Sbjct: 24614 QKTVELDVADVPDPPRGVKV----SDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE 24669
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
W+R R ++ L YQFRV A N G S SE S+ D+
Sbjct: 24670 RWLRVGQARETRYTVI--NLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK 24721
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 175 VSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
V++D+ ++ P + E V LE + F +G P P + W+ + I S+R +
Sbjct: 1785 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1844
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
D L D GE+K TA N G K +L ++ R
Sbjct: 1845 YD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFR 1890
Score = 43.2 bits (97), Expect = 0.005
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
LT+S + + + P FI + E V F SG PSP I WFK++ I S +
Sbjct: 26627 LTLSKELS--DAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS 26684
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+ + L SD G+ A N G A L
Sbjct: 26685 ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
VH P PP P I IL D P +T+ W P DGG+P+ Y VE W
Sbjct: 11099 VHLTVLDVPGPPTGP--INIL-DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW- 11154
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ +L + L+ +Y FRV A N +G L TV+ + S P
Sbjct: 11155 GVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG--PPLDSTPTVAKHKFSPPSPPGK 11212
Query: 189 KRLEDVT 195
+ D+T
Sbjct: 11213 PVVTDIT 11219
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ +SD + +A +L W DGG+ + Y VE + +W+ TA V +
Sbjct: 12495 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWV-TALASVTKTS 12553
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHS 164
+ L P +Y FRV A N G S
Sbjct: 12554 CRVGKLIPGQEYIFRVRAENRFGIS 12578
Score = 42.7 bits (96), Expect = 0.007
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 53 GNHYSASHNAFKPRK-NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
GN+ + N R V+ K RP PP P +I ++ ++ TL W P DGG+
Sbjct: 16115 GNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEK---CTLAWKPPLQDGGSD 16171
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ Y VE W V +T L ++Y FR+ A+N G
Sbjct: 16172 IINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 16221
Score = 42.3 bits (95), Expect = 0.009
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P +I+ + SD T+ W P DGG ++ Y +E W T V
Sbjct: 11799 KPGPVRNLKIVDVSSD----RCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATV 11853
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS-DRASQ-EPPVFIK-RLE 192
L P +T L ++Y FRV A N +G +E V+ + D+ + +PP K E
Sbjct: 11854 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKE 11913
Query: 193 DVTALEN 199
++T + N
Sbjct: 11914 EMTVVWN 11920
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 28/192 (14%)
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
S + W+ ++ +S + IT ++ ++L I D+G +C N G + A L
Sbjct: 25100 STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAEL 25159
Query: 273 ------------CLEAAPKLR--------YPRQYEDGL-LYE----INETIFLKTTIVGK 307
C K++ R E L LY + E + TI
Sbjct: 25160 FVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH 25219
Query: 308 PTPTIEWRHDGHPII---TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W G I D + L I+S D EY + A+N GED+
Sbjct: 25220 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSC 25279
Query: 365 AFLVTVTAPPDP 376
+TVT P P
Sbjct: 25280 KAKLTVTLHPPP 25291
Score = 41.9 bits (94), Expect = 0.012
Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 7/160 (4%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H+ ++ ALND G + S LTV A PV +++E + +F
Sbjct: 4308 HQGEYVCEALNDSGKT---ATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEI 4360
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
P+ WFK EI+ S + +I + + S L + D GE C A+N G
Sbjct: 4361 QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 4420
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
A L + + R+ E E + LK+ + +P
Sbjct: 4421 TATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP 4460
Score = 41.9 bits (94), Expect = 0.012
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-----PPDPPRNVSVTRQVDK 388
K+SV K+ K ++++A+N G + A PPD P V
Sbjct: 8364 KYSVTKLIEGKEY---LFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSN 8420
Query: 389 SVTLDWEPPADDGGCKVGNYIV--EYYRTGWNVWLKAITSR-KTNVTLFDLIEGSEYKFR 445
S+ + W P D+G +G ++ E T W+ K++ + K NV L+EG Y FR
Sbjct: 8421 SMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD--GLLEGLTYVFR 8478
Query: 446 IKAESPYGMSAPSSESSP 463
+ AE+ G S S P
Sbjct: 8479 VCAENAAGPGKFSPPSDP 8496
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L+DV A E D + + P + W+KD E+ + + +D L
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2189
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
I SD + C + T A+L +E A + + ++ +D E+ E+ + +
Sbjct: 2190 IDTSDAEDYSCVLV-EDENVKTTAKLIVEGA-VVEFVKELQD---IEVPESYSGELECIV 2244
Query: 307 KPTPTIE--WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
P IE W H+ + ++ + I+ L + + D+GEY
Sbjct: 2245 SP-ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2290
Score = 41.5 bits (93), Expect = 0.016
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV-------GKP 308
K + T + T++ + + PK P + ++ + +T ++ G+P
Sbjct: 26323 KISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEP 26382
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
PT W DG I + ++S L+IH SD G Y KN G +++ +
Sbjct: 26383 RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKL 26442
Query: 369 TVTAPPD 375
T+ A D
Sbjct: 26443 TIKAIKD 26449
Score = 40.7 bits (91), Expect = 0.027
Identities = 21/84 (25%), Positives = 33/84 (39%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T E + F G P PT+ W + + +S R +TT + S + SDEG
Sbjct: 26073 MTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 26132
Query: 254 EIKCTATNRGGHAVTKARLCLEAA 277
N G + L ++ A
Sbjct: 26133 NYSVVVENSEGKQEAEFTLTIQKA 26156
Score = 40.3 bits (90), Expect = 0.036
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 2483 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 2541
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 2542 KLTVLNMMKDDEGKY----TFYAGENMTSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 2593
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 2594 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 2650
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 2651 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2710
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 2711 VKG-TIYSLRIKNCAIVDESVYGFRL 2735
Score = 40.3 bits (90), Expect = 0.036
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
GRP P P + +S + + L W GG + Y VE G+T W +
Sbjct: 22242 GRPGPVTGPIEVSSVSAE---SCVLSWGEPKDGGGTEITNYIVEKRESGTTAW-QLVNSS 22297
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
V R ++ +T L +Y FRV++ N G S E + ++
Sbjct: 22298 VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPII 22336
Score = 39.9 bits (89), Expect = 0.048
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 79 PPGKPQIIPILSDD-EPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
PP KP+ PI D+ + +++ L W +GG + Y +E T W + V R
Sbjct: 21159 PPSKPKG-PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-KMVCSSVAR 21216
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHS 164
+ L +YQFRV A N G S
Sbjct: 21217 TTFKVPNLVKDAEYQFRVRAENRYGVS 21243
Score = 39.1 bits (87), Expect = 0.084
Identities = 42/236 (17%), Positives = 86/236 (36%), Gaps = 9/236 (3%)
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+W P+ P+ + H L G ++ + ++ + ++ + + P
Sbjct: 5285 QWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSF-QAANAKSAANLKVKELPL 5343
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
+FI L DV E D+ +F S P T W K EI R + D + ++
Sbjct: 5344 IFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIK 5402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
DE + A ++ H T +L +E +L++ +D E +F T +
Sbjct: 5403 SAAFEDEAKYMFEAEDK--H--TSGKLIIEGI-RLKFLTPLKDVTAKEKESAVF--TVEL 5455
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
++W + + T + + K + D + +++A + E
Sbjct: 5456 SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE 5511
Score = 39.1 bits (87), Expect = 0.084
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +D + L W P DGG+ + Y VE S W + + V
Sbjct: 7287 PGPPAAFDI-TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTN 7344
Query: 140 LVLTGLEPPHKYQFRVAALNDVG 162
T L P +Y FRVAA N G
Sbjct: 7345 FKATKLIPNKEYIFRVAAENMYG 7367
Score = 38.7 bits (86), Expect = 0.11
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 2/114 (1%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT--IAWFKDDYEIFSSRRTAITT 235
D+ Q+ P F K+L + F + I PT + W D + ++ R +
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPISDPTMVVEWLHDGKPLEAANRLRMIN 1709
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ L + D G I C ATN+ G T A L ++ L Q +G
Sbjct: 1710 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEG 1763
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/170 (21%), Positives = 65/170 (38%), Gaps = 8/170 (4%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
++ L+DVT + F S P + W+ ++ S + ++ L +
Sbjct: 5702 LRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDV 5760
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
D GE++ TA + HA + P + + + ED + E T L+ V +
Sbjct: 5761 KLEDAGEVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEE-GATAVLECE-VSR 5813
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++W +G I+ + EI + L IH D Y AK+
Sbjct: 5814 ENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 37.9 bits (84), Expect = 0.19
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH-KYQFRV 155
++L W DGG+ + GY VE + W+ A E +TGL+ +Y FRV
Sbjct: 6609 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRV 6667
Query: 156 AALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
+A N VG E + + S PP+
Sbjct: 6668 SARNRVGTGEPVETDNPVEARSKYDVPGPPL 6698
Score = 36.3 bits (80), Expect = 0.59
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK--IHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P+ T R ++S + K I D GEY I +N GE +
Sbjct: 1061 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1120
Query: 364 AA 365
A+
Sbjct: 1121 AS 1122
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E++ L+ I G P+PT+ W + + I + +I+ + L I A D G + A
Sbjct: 912 ESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 971
Query: 356 KNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQ 385
N G T+ +L + +VT +
Sbjct: 972 VNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Score = 35.5 bits (78), Expect = 1.0
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 8/131 (6%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+AS+ +NVH + RP+PP + +D + + L W +GG+ + Y
Sbjct: 8981 TASNRLGSVFRNVHVEVYDRPSPPRNLAV----TDIKAESCYLTWDAPLDNGGSEITHYV 9036
Query: 117 VECNRLG--STEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
++ EW V + + L P +Y+FRV A+N G S+ + SD +
Sbjct: 9037 IDKRDASRKKAEWEEVTNTAVEK-RYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVV 9094
Query: 175 VSSDRASQEPP 185
+ PP
Sbjct: 9095 IQDPYRLPGPP 9105
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G+PTP + W G I + + R I T + L I ++ D G Y + N G D+
Sbjct: 26857 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDS 26916
Query: 364 A 364
A
Sbjct: 26917 A 26917
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 1/69 (1%)
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ T + PT +EW HDG P+ +R+ + + L A D G +A N G
Sbjct: 1679 RLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1738
Query: 361 ED-TAAFLV 368
D T+A L+
Sbjct: 1739 TDHTSATLI 1747
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 3476 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 3535
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 3536 GKTICSAYLKINSKGEGHKDTETESAVAKSL 3566
Score = 33.1 bits (72), Expect = 5.5
Identities = 18/68 (26%), Positives = 29/68 (42%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ KPT ++W H+G + +I + T L+I D G Y+ N GE +
Sbjct: 25900 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEAS 25959
Query: 364 AAFLVTVT 371
+ VT
Sbjct: 25960 DYATLDVT 25967
Score = 32.7 bits (71), Expect = 7.3
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE--CNRLGSTEWIRTAPPIVLR 137
PG P I + D ++ KW P DGG+ + Y +E +EWI +
Sbjct: 8305 PGPP-INFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI-VVTSTLRH 8362
Query: 138 PELVLTGLEPPHKYQFRVAALNDVG 162
+ +T L +Y FRV A N G
Sbjct: 8363 CKYSVTKLIEGKEYLFRVRAENRFG 8387
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 187 bits (456), Expect = 2e-46
Identities = 118/393 (30%), Positives = 177/393 (45%), Gaps = 10/393 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PGKP I + D + + W P DGGA +R Y +E +WI +
Sbjct: 2051 KPGAPGKPTITAVTKD----SCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI 2106
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ L +Y+FRV N G S +SE+S+ +T SD Q P F + L ++
Sbjct: 2107 RETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPH-FKEELRNLN 2165
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--LLFHQILPSDEG 253
+G P P + W++ EI + + L+ + D
Sbjct: 2166 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 2225
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLYEIN-ETIFLKTTIVGKPTPT 311
+ ATN+GG A L +E K+ P+ E G ++ + E + +K GKP P
Sbjct: 2226 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 2285
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKI-HSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W+ I + ++ +T F+ L + +R D G Y + AKN G D + V
Sbjct: 2286 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
PDPPR V V+ SV L W PA DGG K+ NYIVE T WL+ +R+T
Sbjct: 2346 ADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR 2405
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
T+ +L + Y+FR+ AE+ +G+S PS S P
Sbjct: 2406 YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 2438
Score = 180 bits (438), Expect = 2e-44
Identities = 110/395 (27%), Positives = 186/395 (47%), Gaps = 10/395 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P+ PG+ +I+ I D ++TL+W DGG + GY VE + G + W ++ +
Sbjct: 1657 KPSQPGELEILSISKD----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 1712
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ + GL +Y+FRV A N+ G S + +++ + S E P K ++DVT
Sbjct: 1713 KDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEMKDVT 1770
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P I W++ E+ SR+ +++D T L DEG
Sbjct: 1771 TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 1830
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C ATN G T ++L L+A P+ ++ + T+ L +G+P P + W
Sbjct: 1831 TCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF 1890
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKR-SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
H + + I I T ++ L + + +R + G+Y++Q N+ G A V + P
Sbjct: 1891 HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKP 1950
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVE--YYRTGWNVWLKAITSRKTNV 431
D P + + + S + W+PPADDGG + NY+VE + G L + T
Sbjct: 1951 DKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTC 2010
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ +L E + Y FR+ A++ +G+S P SS V I
Sbjct: 2011 RIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 2045
Score = 125 bits (301), Expect = 1e-27
Identities = 105/402 (26%), Positives = 167/402 (41%), Gaps = 25/402 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+ P +P++ + + NA++++W HDGG+ + GY VE + W++ L
Sbjct: 68 PSAPTRPEVYHVSA----NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCL 123
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPPVF------IK 189
+TGL +YQFR ALN G S SE S ++ + A P V +
Sbjct: 124 ECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPGVTDVQRSTVS 183
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
+ A + P + W K +Y I S +T F
Sbjct: 184 LIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRV 243
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYP-RQYEDGLLYEINETIFLKTT 303
+ + G I + + G VT C + A PK R + D + + L
Sbjct: 244 LAKNAAGVISKGSESTG--PVT----CRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 297
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP P I W + +++ + T K + I RSD G+Y + KN G
Sbjct: 298 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 357
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ +V V P P ++V+R + TL W P +DGG ++ +YIVE T W+
Sbjct: 358 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 417
Query: 424 ITSRKT-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + LI+ +EY FR++A + YG P ES P+
Sbjct: 418 EGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVP-VESEPI 458
Score = 123 bits (296), Expect = 4e-27
Identities = 110/397 (27%), Positives = 158/397 (39%), Gaps = 20/397 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + I D + +TL W P DGG+ + GY VE + + W+R V
Sbjct: 1159 PGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 1217
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
TGL +Y+ RV A+N G S S + A P R+ D T
Sbjct: 1218 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQN-PRVTDTTRTSV 1276
Query: 200 D---KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEI 255
V S + I K D ++ T T + L H LP E
Sbjct: 1277 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT--TPTKIREYTLTH--LPQGAEYRF 1332
Query: 256 KCTATNRGGHAV-TKARLCLEAAPKLRYP-----RQYEDGLLYEINETIFLKTTIVGKPT 309
+ A N GG + ++ L YP +Y++G+ I L I GKP
Sbjct: 1333 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 1392
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P +W +G I R I+ + + L I A R D G Y + +N G+ V
Sbjct: 1393 PICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVR 1450
Query: 370 VTAPPDPPRNVSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P+ P + +SV + W PPADDGG + YI+E W + R
Sbjct: 1451 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVR 1510
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T++ + L E EY FR+ AE+ +G+S P PV
Sbjct: 1511 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 1547
Score = 122 bits (294), Expect = 7e-27
Identities = 104/401 (25%), Positives = 173/401 (43%), Gaps = 20/401 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPP-IV 135
P+PPG P+ + + I ++W DGG + Y V+ S W R +V
Sbjct: 467 PSPPGIPEEVGTGKEH----IIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVV 522
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +T L YQFRV A+N G+S SE S+ ++ + PP R+ D T
Sbjct: 523 YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPS-APRVVDTT 581
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEG 253
+ G + + + + E + + + T+ + F + +
Sbjct: 582 KHSISLAWTKPMYDG-GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKY 640
Query: 254 EIKCTATN-RGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEIN----ETIFLKTTIVGK 307
+ A N +G +++ +E ++ P + D L + ++ L ++ G+
Sbjct: 641 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 700
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P I W G + + R I T +S+L + R D G+Y I+A+N G+ +A L
Sbjct: 701 PPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL 758
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V V P P +V V SVT+ WE P DGG + NYIVE + K +T++
Sbjct: 759 VKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAF-KTVTTK 817
Query: 428 --KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
KT + L+EG+ + FR+ E+ YG+ P S V +
Sbjct: 818 CSKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLV 858
Score = 116 bits (279), Expect = 5e-25
Identities = 98/401 (24%), Positives = 170/401 (42%), Gaps = 23/401 (5%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVL 136
APPGKPQ P ++D +++L W+ +GG+ + GY +E ++ EW + P +
Sbjct: 1258 APPGKPQN-PRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 1316
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R E LT L +Y+FRV A N G +E+ + V+ + + + E +
Sbjct: 1317 R-EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFV 1375
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ + + G P P W K+ +I S+R I T E+ + L+ + D G
Sbjct: 1376 RQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYD 1433
Query: 257 CTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
N+ G ++ + +P P +Y+D + + + + + +
Sbjct: 1434 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR--VSWRPPADDGGADILGYI 1491
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG------EDTAAFLVT 369
+ + I + + L + K + +++ A+N G + T
Sbjct: 1492 LERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 1551
Query: 370 VTAPPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
PP+PP N V K SV+L W P DDGG +V Y +E T + K + K
Sbjct: 1552 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD---KVVRHNK 1608
Query: 429 TNV-----TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + T+ L+ +EY+FRI A++ G+S S S PV
Sbjct: 1609 TQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 1649
Score = 108 bits (260), Expect = 9e-23
Identities = 105/394 (26%), Positives = 163/394 (41%), Gaps = 32/394 (8%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++T+ W T DGGAP+ Y VE R + +T + ++GL + FR
Sbjct: 779 DSVTITWEIPTIDGGAPINNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMHYFR 837
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE--DVTALENDKVEFHVTFSGIP 212
V N G E SD + VS E P+ +LE DVT + G
Sbjct: 838 VLPENIYGIGEPCETSDAVLVS------EVPLVPAKLEVVDVTKSTVTLAWEKPLYDG-G 890
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IKCTATNRGG----- 264
S + + + + R + T + T +L H + +EGE + A N G
Sbjct: 891 SRLTGYVLEACKAGTERWMKVVTLKPT--VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPR 948
Query: 265 HAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
VT + L P + + + + L I G+P P W G +
Sbjct: 949 ETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRE 1008
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+R+ + K + L I D GEY ++ KN+ G V + P PP
Sbjct: 1009 SERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKVIILDKPGPPTGPIKI 1068
Query: 384 RQVD-KSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEG 439
++D S+T+ WEPP DGG + Y+VE +R GW +++T ++ L EG
Sbjct: 1069 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVT--RSTFKFTRLTEG 1126
Query: 440 SEYKFRIKAESPYGM-SAPSSE----SSPVRIPG 468
+EY FR+ A + +G+ S SE S +RIPG
Sbjct: 1127 NEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG 1160
Score = 101 bits (242), Expect = 1e-20
Identities = 92/398 (23%), Positives = 157/398 (39%), Gaps = 18/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR--TAPPI 134
P P K +++ + + +TL W +DGG+ L GY +E + G+ W++ T P
Sbjct: 862 PLVPAKLEVVDVTK----STVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 917
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
VL E +T L +Y FR+ A N+ G S E +TV R + + +
Sbjct: 918 VL--EHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 975
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
VE + +G P P +WF ++ S R + T + L + D GE
Sbjct: 976 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 1035
Query: 255 IKCTATNRGGHAVTKAR-LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
N G + + + L+ P + ++ + + TI + + P
Sbjct: 1036 YTLELKNVTGTTLETIKVIILDKPGPPTGPIKIDE--IDATSITISWEPPELDGGAPLSG 1093
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
+ + + +S + S K + +++ A N IG + ++
Sbjct: 1094 YVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 1153
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITS 426
+ P PP + + +TL W PP DDGG +V YIVE + W++ +
Sbjct: 1154 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 1213
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T L EG EY+ R+ A + G PS S P+
Sbjct: 1214 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 1251
Score = 86.6 bits (205), Expect = 4e-16
Identities = 92/404 (22%), Positives = 164/404 (40%), Gaps = 35/404 (8%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE---CNRLGSTEWIRTAPPIVL 136
PG+P + +D + + ++L W+ +DGG+ + GY +E + +G W++ IV
Sbjct: 169 PGRPGV----TDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 224
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+T L Y+FRV A N G S SE + +T + A + + + D V
Sbjct: 225 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 284
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI--TTDESTSVLLFHQILPSDE 252
T + G P P I W K D E+ + ++ T +T+V+ F SD
Sbjct: 285 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCD--RSDS 342
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAP----KLRYPRQYED------GLLYEINETIFLKT 302
G+ T N G + + +P KL R ++ L E
Sbjct: 343 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 402
Query: 303 TIVGKPTPTIEWRH-DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + T + W +G + I + ++ + + G ++++ I+
Sbjct: 403 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG-VPVESEPIVAR 461
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV---EYYRTGWN 418
++ T+ +PP P V ++ + + W P DGG ++ NY+V E W
Sbjct: 462 NS----FTIPSPPGIPEEVGTGKE---HIIIQWTKPESDGGNEISNYLVDKREKESLRWT 514
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
K T + + L+EG +Y+FR+ A + G S PS S+
Sbjct: 515 RVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSN 558
Score = 83.8 bits (198), Expect = 3e-15
Identities = 80/313 (25%), Positives = 139/313 (44%), Gaps = 24/313 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P P + D ++++L W+ DGG+ + GY +E + + +R +
Sbjct: 1555 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNKTQITTT 1614
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRL-EDVT 195
+TGL P +YQFR+ A NDVG S S S+ + D+ SQ + I + +D
Sbjct: 1615 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 1674
Query: 196 ALENDKVE---------FHVTFSGIPSPTIAWFKDDYEIFSSRRTAI-TTDESTSVLLFH 245
L+ +K E + V + S AW K + E ++ I E+T +
Sbjct: 1675 TLQWEKPECDGGKEILGYWVEYR--QSGDSAWKKSNKERIKDKQFTIGGLLEATE----Y 1728
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ E E + R ++ K +L AP +R ++ +D + ++ E L IV
Sbjct: 1729 EFRVFAENETGLSRPRRTAMSI-KTKLTSGEAPGIR--KEMKD-VTTKLGEAAQLSCQIV 1784
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-DTA 364
G+P P I+W G +I + ++S + L + + ++ D G Y A N +GE +T+
Sbjct: 1785 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844
Query: 365 AFLVTVTAPPDPP 377
+ L+ P P
Sbjct: 1845 SKLLLQATPQFHP 1857
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 351 YQIQAKNIIGEDT---AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
+++ A+N G + +V + +P P P ++T S + W+PPA DGG K
Sbjct: 2023 FRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAK 2082
Query: 405 VGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
+ NY +E N W+ T R+T ++ +LIEG EY+FR+K E+ G S S S
Sbjct: 2083 IRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE 2142
Query: 463 PV 464
P+
Sbjct: 2143 PI 2144
Score = 66.9 bits (156), Expect = 4e-10
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 12/193 (6%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI---FSSRRTAITT 235
R + PP F L + TA + V F VT + P P + W+K +I + ++ +
Sbjct: 2911 RLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFES 2970
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-----KLR--YPRQYED 288
D+ L + + D+ E A N+ G KA+L + P LR + R +
Sbjct: 2971 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 3030
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSD 347
E +++ + + G P PT++W DG P+ IEI + L I D
Sbjct: 3031 AECQE-GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 3089
Query: 348 RGEYQIQAKNIIG 360
G Y++ A N G
Sbjct: 3090 TGYYRVTATNTAG 3102
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT--SRKT 429
APP P+N VT SV+L W P D+GG KV Y++E + + W K T ++
Sbjct: 1258 APPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 1317
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
TL L +G+EY+FR+ A + G P+ V++
Sbjct: 1318 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 1354
Score = 62.9 bits (146), Expect = 6e-09
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 6/179 (3%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W + E+ +S S L Q DEG + C + + G + K + L
Sbjct: 4295 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVKCQYDLT 4352
Query: 276 AAPKLR-YPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ +L P INE + I G+P+P IEW + PI + IS +
Sbjct: 4353 LSKELSDAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRS 4412
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPDPPRNVSVTRQVDKSV 390
L+I +A SD G+Y I+AKN G+ +A A L+ + +P R V + D S+
Sbjct: 4413 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 4471
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/110 (34%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P I + + +IT+ W P DGGAPL GY VE W+ + V
Sbjct: 1058 KPGPPTGPIKI---DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-V 1113
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
R T L ++Y FRVAA N G +Y + S+V+ S PP
Sbjct: 1114 TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQ-SEVIECRSSIRIPGPP 1162
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEP----PVFIKRLEDVTALENDKVEFHVTFS 209
+V+ +++ S+ +T ++ + EP PV + L+D T + +F V +
Sbjct: 4044 KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT 4103
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P PT W KD I + ++ D+ L H+ SD G CT N G +
Sbjct: 4104 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 4163
Query: 270 ARLCLEA 276
+L ++A
Sbjct: 4164 CKLTIKA 4170
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTN 430
PP P V ++++ WE P DGG K+ Y VE +W+K + + N
Sbjct: 67 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECN 126
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG EY+FR A + G+S S S P+
Sbjct: 127 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 160
Score = 52.8 bits (121), Expect = 6e-06
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 4/148 (2%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+L + + ++ V A N G + V S P+F + L + E
Sbjct: 2976 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 3035
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQILPSDEGEIKC 257
V F + SGIP PT+ W KD + I + L LP D G +
Sbjct: 3036 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 3095
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQ 285
TATN G +A L +E +LRY +Q
Sbjct: 3096 TATNTAGSTSCQAHLQVE---RLRYKKQ 3120
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P PT+ W G + T R +++ T S +I S + SD G Y + +N G+ A
Sbjct: 3813 GEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAE 3872
Query: 366 FLVTV 370
F +T+
Sbjct: 3873 FTLTI 3877
Score = 43.6 bits (98), Expect = 0.004
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 66 RKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST 125
+K V A P PP ++ SD +++ L W DGG+ + Y VE +
Sbjct: 2338 QKTVELDVADVPDPPRGVKV----SDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE 2393
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
W+R R ++ L YQFRV A N G S SE S+ D+
Sbjct: 2394 RWLRVGQARETRYTVI--NLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK 2445
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 28/192 (14%)
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
S + W+ ++ +S + IT ++ ++L I D+G +C N G + A L
Sbjct: 2824 STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAEL 2883
Query: 273 ------------CLEAAPKLR--------YPRQYEDGL-LYE----INETIFLKTTIVGK 307
C K++ R E L LY + E + TI
Sbjct: 2884 FVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH 2943
Query: 308 PTPTIEWRHDGHPII---TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W G I D + L I+S D EY + A+N GED+
Sbjct: 2944 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSC 3003
Query: 365 AFLVTVTAPPDP 376
+TVT P P
Sbjct: 3004 KAKLTVTLHPPP 3015
Score = 42.3 bits (95), Expect = 0.009
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
LT+S + + + P FI + E V F SG PSP I WFK++ I S +
Sbjct: 4351 LTLSKELS--DAPAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSNVS 4408
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+ + L SD G+ A N G A L
Sbjct: 4409 ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 4448
Score = 41.5 bits (93), Expect = 0.016
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV-------GKP 308
K + T + T++ + + PK P + ++ + +T ++ G+P
Sbjct: 4047 KISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEP 4106
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
PT W DG I + ++S L+IH SD G Y KN G +++ +
Sbjct: 4107 RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKL 4166
Query: 369 TVTAPPD 375
T+ A D
Sbjct: 4167 TIKAIKD 4173
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Query: 407 NYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
NYIVE +G W +S ++T + + L + EY FR+ +E+ +G+S P ES+P+
Sbjct: 2 NYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKP-LESAPI 59
Score = 40.3 bits (90), Expect = 0.036
Identities = 21/84 (25%), Positives = 33/84 (39%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T E + F G P PT+ W + + +S R +TT + S + SDEG
Sbjct: 3797 MTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEG 3856
Query: 254 EIKCTATNRGGHAVTKARLCLEAA 277
N G + L ++ A
Sbjct: 3857 NYSVVVENSEGKQEAEFTLTIQKA 3880
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G+PTP + W G I + + R I T + L I ++ D G Y + N G D+
Sbjct: 4581 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDS 4640
Query: 364 A 364
A
Sbjct: 4641 A 4641
Score = 33.1 bits (72), Expect = 5.5
Identities = 18/68 (26%), Positives = 29/68 (42%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ KPT ++W H+G + +I + T L+I D G Y+ N GE +
Sbjct: 3624 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGERS 3683
Query: 364 AAFLVTVT 371
+ VT
Sbjct: 3684 DYATLDVT 3691
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 187 bits (456), Expect = 2e-46
Identities = 118/393 (30%), Positives = 177/393 (45%), Gaps = 10/393 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PGKP I + D + + W P DGGA +R Y +E +WI +
Sbjct: 2051 KPGAPGKPTITAVTKD----SCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI 2106
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ L +Y+FRV N G S +SE+S+ +T SD Q P F + L ++
Sbjct: 2107 RETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPH-FKEELRNLN 2165
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--LLFHQILPSDEG 253
+G P P + W++ EI + + L+ + D
Sbjct: 2166 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 2225
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLYEIN-ETIFLKTTIVGKPTPT 311
+ ATN+GG A L +E K+ P+ E G ++ + E + +K GKP P
Sbjct: 2226 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 2285
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKI-HSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W+ I + ++ +T F+ L + +R D G Y + AKN G D + V
Sbjct: 2286 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
PDPPR V V+ SV L W PA DGG K+ NYIVE T WL+ +R+T
Sbjct: 2346 ADVPDPPRGVKVSDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR 2405
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
T+ +L + Y+FR+ AE+ +G+S PS S P
Sbjct: 2406 YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 2438
Score = 180 bits (438), Expect = 2e-44
Identities = 110/395 (27%), Positives = 186/395 (47%), Gaps = 10/395 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P+ PG+ +I+ I D ++TL+W DGG + GY VE + G + W ++ +
Sbjct: 1657 KPSQPGELEILSISKD----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 1712
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ + GL +Y+FRV A N+ G S + +++ + S E P K ++DVT
Sbjct: 1713 KDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEMKDVT 1770
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P I W++ E+ SR+ +++D T L DEG
Sbjct: 1771 TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 1830
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C ATN G T ++L L+A P+ ++ + T+ L +G+P P + W
Sbjct: 1831 TCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF 1890
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKR-SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
H + + I I T ++ L + + +R + G+Y++Q N+ G A V + P
Sbjct: 1891 HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKP 1950
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVE--YYRTGWNVWLKAITSRKTNV 431
D P + + + S + W+PPADDGG + NY+VE + G L + T
Sbjct: 1951 DKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTC 2010
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ +L E + Y FR+ A++ +G+S P SS V I
Sbjct: 2011 RIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 2045
Score = 125 bits (301), Expect = 1e-27
Identities = 105/402 (26%), Positives = 167/402 (41%), Gaps = 25/402 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+ P +P++ + + NA++++W HDGG+ + GY VE + W++ L
Sbjct: 68 PSAPTRPEVYHVSA----NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCL 123
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPPVF------IK 189
+TGL +YQFR ALN G S SE S ++ + A P V +
Sbjct: 124 ECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPGVTDVQRSTVS 183
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
+ A + P + W K +Y I S +T F
Sbjct: 184 LIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRV 243
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYP-RQYEDGLLYEINETIFLKTT 303
+ + G I + + G VT C + A PK R + D + + L
Sbjct: 244 LAKNAAGVISKGSESTG--PVT----CRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 297
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP P I W + +++ + T K + I RSD G+Y + KN G
Sbjct: 298 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 357
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ +V V P P ++V+R + TL W P +DGG ++ +YIVE T W+
Sbjct: 358 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 417
Query: 424 ITSRKT-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + LI+ +EY FR++A + YG P ES P+
Sbjct: 418 EGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVP-VESEPI 458
Score = 123 bits (296), Expect = 4e-27
Identities = 110/397 (27%), Positives = 158/397 (39%), Gaps = 20/397 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + I D + +TL W P DGG+ + GY VE + + W+R V
Sbjct: 1159 PGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 1217
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
TGL +Y+ RV A+N G S S + A P R+ D T
Sbjct: 1218 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQN-PRVTDTTRTSV 1276
Query: 200 D---KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEI 255
V S + I K D ++ T T + L H LP E
Sbjct: 1277 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT--TPTKIREYTLTH--LPQGAEYRF 1332
Query: 256 KCTATNRGGHAV-TKARLCLEAAPKLRYP-----RQYEDGLLYEINETIFLKTTIVGKPT 309
+ A N GG + ++ L YP +Y++G+ I L I GKP
Sbjct: 1333 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 1392
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P +W +G I R I+ + + L I A R D G Y + +N G+ V
Sbjct: 1393 PICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVR 1450
Query: 370 VTAPPDPPRNVSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P+ P + +SV + W PPADDGG + YI+E W + R
Sbjct: 1451 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVR 1510
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T++ + L E EY FR+ AE+ +G+S P PV
Sbjct: 1511 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 1547
Score = 122 bits (294), Expect = 7e-27
Identities = 104/401 (25%), Positives = 173/401 (43%), Gaps = 20/401 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPP-IV 135
P+PPG P+ + + I ++W DGG + Y V+ S W R +V
Sbjct: 467 PSPPGIPEEVGTGKEH----IIIQWTKPESDGGNEISNYLVDKREKESLRWTRVNKDYVV 522
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +T L YQFRV A+N G+S SE S+ ++ + PP R+ D T
Sbjct: 523 YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSNFISCREPSYTPGPPS-APRVVDTT 581
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEG 253
+ G + + + + E + + + T+ + F + +
Sbjct: 582 KHSISLAWTKPMYDG-GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKY 640
Query: 254 EIKCTATN-RGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEIN----ETIFLKTTIVGK 307
+ A N +G +++ +E ++ P + D L + ++ L ++ G+
Sbjct: 641 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 700
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P I W G + + R I T +S+L + R D G+Y I+A+N G+ +A L
Sbjct: 701 PPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL 758
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V V P P +V V SVT+ WE P DGG + NYIVE + K +T++
Sbjct: 759 VKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPINNYIVEKREAAMRAF-KTVTTK 817
Query: 428 --KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
KT + L+EG+ + FR+ E+ YG+ P S V +
Sbjct: 818 CSKTLYRISGLVEGTMHYFRVLPENIYGIGEPCETSDAVLV 858
Score = 116 bits (279), Expect = 5e-25
Identities = 98/401 (24%), Positives = 170/401 (42%), Gaps = 23/401 (5%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVL 136
APPGKPQ P ++D +++L W+ +GG+ + GY +E ++ EW + P +
Sbjct: 1258 APPGKPQN-PRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 1316
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R E LT L +Y+FRV A N G +E+ + V+ + + + E +
Sbjct: 1317 R-EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFV 1375
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ + + G P P W K+ +I S+R I T E+ + L+ + D G
Sbjct: 1376 RQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYD 1433
Query: 257 CTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
N+ G ++ + +P P +Y+D + + + + + +
Sbjct: 1434 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR--VSWRPPADDGGADILGYI 1491
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG------EDTAAFLVT 369
+ + I + + L + K + +++ A+N G + T
Sbjct: 1492 LERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 1551
Query: 370 VTAPPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
PP+PP N V K SV+L W P DDGG +V Y +E T + K + K
Sbjct: 1552 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD---KVVRHNK 1608
Query: 429 TNV-----TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + T+ L+ +EY+FRI A++ G+S S S PV
Sbjct: 1609 TQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 1649
Score = 108 bits (260), Expect = 9e-23
Identities = 105/394 (26%), Positives = 163/394 (41%), Gaps = 32/394 (8%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++T+ W T DGGAP+ Y VE R + +T + ++GL + FR
Sbjct: 779 DSVTITWEIPTIDGGAPINNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMHYFR 837
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE--DVTALENDKVEFHVTFSGIP 212
V N G E SD + VS E P+ +LE DVT + G
Sbjct: 838 VLPENIYGIGEPCETSDAVLVS------EVPLVPAKLEVVDVTKSTVTLAWEKPLYDG-G 890
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IKCTATNRGG----- 264
S + + + + R + T + T +L H + +EGE + A N G
Sbjct: 891 SRLTGYVLEACKAGTERWMKVVTLKPT--VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPR 948
Query: 265 HAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
VT + L P + + + + L I G+P P W G +
Sbjct: 949 ETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRE 1008
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+R+ + K + L I D GEY ++ KN+ G V + P PP
Sbjct: 1009 SERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTLETIKVIILDKPGPPTGPIKI 1068
Query: 384 RQVD-KSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEG 439
++D S+T+ WEPP DGG + Y+VE +R GW +++T ++ L EG
Sbjct: 1069 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVT--RSTFKFTRLTEG 1126
Query: 440 SEYKFRIKAESPYGM-SAPSSE----SSPVRIPG 468
+EY FR+ A + +G+ S SE S +RIPG
Sbjct: 1127 NEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG 1160
Score = 101 bits (242), Expect = 1e-20
Identities = 92/398 (23%), Positives = 157/398 (39%), Gaps = 18/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR--TAPPI 134
P P K +++ + + +TL W +DGG+ L GY +E + G+ W++ T P
Sbjct: 862 PLVPAKLEVVDVTK----STVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 917
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
VL E +T L +Y FR+ A N+ G S E +TV R + + +
Sbjct: 918 VL--EHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 975
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
VE + +G P P +WF ++ S R + T + L + D GE
Sbjct: 976 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 1035
Query: 255 IKCTATNRGGHAVTKAR-LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
N G + + + L+ P + ++ + + TI + + P
Sbjct: 1036 YTLELKNVTGTTLETIKVIILDKPGPPTGPIKIDE--IDATSITISWEPPELDGGAPLSG 1093
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
+ + + +S + S K + +++ A N IG + ++
Sbjct: 1094 YVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 1153
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITS 426
+ P PP + + +TL W PP DDGG +V YIVE + W++ +
Sbjct: 1154 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 1213
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T L EG EY+ R+ A + G PS S P+
Sbjct: 1214 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 1251
Score = 86.6 bits (205), Expect = 4e-16
Identities = 92/404 (22%), Positives = 164/404 (40%), Gaps = 35/404 (8%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE---CNRLGSTEWIRTAPPIVL 136
PG+P + +D + + ++L W+ +DGG+ + GY +E + +G W++ IV
Sbjct: 169 PGRPGV----TDVQRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 224
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+T L Y+FRV A N G S SE + +T + A + + + D V
Sbjct: 225 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 284
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI--TTDESTSVLLFHQILPSDE 252
T + G P P I W K D E+ + ++ T +T+V+ F SD
Sbjct: 285 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCD--RSDS 342
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAP----KLRYPRQYED------GLLYEINETIFLKT 302
G+ T N G + + +P KL R ++ L E
Sbjct: 343 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 402
Query: 303 TIVGKPTPTIEWRH-DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + T + W +G + I + ++ + + G ++++ I+
Sbjct: 403 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG-VPVESEPIVAR 461
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV---EYYRTGWN 418
++ T+ +PP P V ++ + + W P DGG ++ NY+V E W
Sbjct: 462 NS----FTIPSPPGIPEEVGTGKE---HIIIQWTKPESDGGNEISNYLVDKREKESLRWT 514
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
K T + + L+EG +Y+FR+ A + G S PS S+
Sbjct: 515 RVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSERSN 558
Score = 83.8 bits (198), Expect = 3e-15
Identities = 80/313 (25%), Positives = 139/313 (44%), Gaps = 24/313 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P P + D ++++L W+ DGG+ + GY +E + + +R +
Sbjct: 1555 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKVVRHNKTQITTT 1614
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRL-EDVT 195
+TGL P +YQFR+ A NDVG S S S+ + D+ SQ + I + +D
Sbjct: 1615 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 1674
Query: 196 ALENDKVE---------FHVTFSGIPSPTIAWFKDDYEIFSSRRTAI-TTDESTSVLLFH 245
L+ +K E + V + S AW K + E ++ I E+T +
Sbjct: 1675 TLQWEKPECDGGKEILGYWVEYR--QSGDSAWKKSNKERIKDKQFTIGGLLEATE----Y 1728
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ E E + R ++ K +L AP +R ++ +D + ++ E L IV
Sbjct: 1729 EFRVFAENETGLSRPRRTAMSI-KTKLTSGEAPGIR--KEMKD-VTTKLGEAAQLSCQIV 1784
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-DTA 364
G+P P I+W G +I + ++S + L + + ++ D G Y A N +GE +T+
Sbjct: 1785 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 1844
Query: 365 AFLVTVTAPPDPP 377
+ L+ P P
Sbjct: 1845 SKLLLQATPQFHP 1857
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 351 YQIQAKNIIGEDT---AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
+++ A+N G + +V + +P P P ++T S + W+PPA DGG K
Sbjct: 2023 FRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAK 2082
Query: 405 VGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
+ NY +E N W+ T R+T ++ +LIEG EY+FR+K E+ G S S S
Sbjct: 2083 IRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE 2142
Query: 463 PV 464
P+
Sbjct: 2143 PI 2144
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT--SRKT 429
APP P+N VT SV+L W P D+GG KV Y++E + + W K T ++
Sbjct: 1258 APPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 1317
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
TL L +G+EY+FR+ A + G P+ V++
Sbjct: 1318 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 1354
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/190 (25%), Positives = 80/190 (42%), Gaps = 12/190 (6%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI---FSSRRTAITT 235
R + PP F L + TA + V F VT + P P + W+K +I + ++ +
Sbjct: 2911 RLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFES 2970
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-----KLR--YPRQYED 288
D+ L + + D+ E A N+ G KA+L + P LR + R +
Sbjct: 2971 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 3030
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSD 347
E +++ + + G P PT++W DG P+ IEI + L I D
Sbjct: 3031 AECQE-GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 3089
Query: 348 RGEYQIQAKN 357
G Y++ A N
Sbjct: 3090 TGYYRVTATN 3099
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/110 (34%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P I + + +IT+ W P DGGAPL GY VE W+ + V
Sbjct: 1058 KPGPPTGPIKI---DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-V 1113
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
R T L ++Y FRVAA N G +Y + S+V+ S PP
Sbjct: 1114 TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQ-SEVIECRSSIRIPGPP 1162
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTN 430
PP P V ++++ WE P DGG K+ Y VE +W+K + + N
Sbjct: 67 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECN 126
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG EY+FR A + G+S S S P+
Sbjct: 127 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 160
Score = 44.0 bits (99), Expect = 0.003
Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 1/124 (0%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+L + + ++ V A N G + V S P+F + L + E
Sbjct: 2976 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 3035
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQILPSDEGEIKC 257
V F + SGIP PT+ W KD + I + L LP D G +
Sbjct: 3036 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 3095
Query: 258 TATN 261
TATN
Sbjct: 3096 TATN 3099
Score = 43.6 bits (98), Expect = 0.004
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 66 RKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST 125
+K V A P PP ++ SD +++ L W DGG+ + Y VE +
Sbjct: 2338 QKTVELDVADVPDPPRGVKV----SDASRDSVNLTWTEPASDGGSKITNYIVEKCATTAE 2393
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
W+R R ++ L YQFRV A N G S SE S+ D+
Sbjct: 2394 RWLRVGQARETRYTVI--NLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK 2445
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 28/192 (14%)
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
S + W+ ++ +S + IT ++ ++L I D+G +C N G + A L
Sbjct: 2824 STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAEL 2883
Query: 273 ------------CLEAAPKLR--------YPRQYEDGL-LYE----INETIFLKTTIVGK 307
C K++ R E L LY + E + TI
Sbjct: 2884 FVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH 2943
Query: 308 PTPTIEWRHDGHPII---TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W G I D + L I+S D EY + A+N GED+
Sbjct: 2944 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSC 3003
Query: 365 AFLVTVTAPPDP 376
+TVT P P
Sbjct: 3004 KAKLTVTLHPPP 3015
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 2/59 (3%)
Query: 407 NYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
NYIVE +G W +S ++T + + L + EY FR+ +E+ +G+S P ES+P+
Sbjct: 2 NYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKP-LESAPI 59
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 187 bits (455), Expect = 2e-46
Identities = 118/393 (30%), Positives = 177/393 (45%), Gaps = 10/393 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PGKP I + D + + W P DGGA +R Y +E +WI +
Sbjct: 24327 KPGAPGKPTITAVTKD----SCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEI 24382
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ L +Y+FRV N G S +SE+S+ +T SD Q P F + L ++
Sbjct: 24383 RETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPH-FKEELRNLN 24441
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--LLFHQILPSDEG 253
+G P P + W++ EI + + L+ + D
Sbjct: 24442 VRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDAT 24501
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLYEIN-ETIFLKTTIVGKPTPT 311
+ ATN+GG A L +E K+ P+ E G ++ + E + +K GKP P
Sbjct: 24502 VYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPV 24561
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKI-HSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W+ I + ++ +T F+ L + +R D G Y + AKN G D + V
Sbjct: 24562 ITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
PDPPR V V+ SV L W PA DGG K+ NYIVE T WL+ +R+T
Sbjct: 24622 ADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETR 24681
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
T+ +L + Y+FR+ AE+ +G+S PS S P
Sbjct: 24682 YTVINLFGKTSYQFRVIAENKFGLSKPSEPSEP 24714
Score = 180 bits (438), Expect = 2e-44
Identities = 110/395 (27%), Positives = 186/395 (47%), Gaps = 10/395 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P+ PG+ +I+ I D ++TL+W DGG + GY VE + G + W ++ +
Sbjct: 23933 KPSQPGELEILSISKD----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 23988
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ + GL +Y+FRV A N+ G S + +++ + S E P K ++DVT
Sbjct: 23989 KDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTA--MSIKTKLTSGEAPGIRKEMKDVT 24046
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P I W++ E+ SR+ +++D T L DEG
Sbjct: 24047 TKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C ATN G T ++L L+A P+ ++ + T+ L +G+P P + W
Sbjct: 24107 TCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF 24166
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKR-SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
H + + I I T ++ L + + +R + G+Y++Q N+ G A V + P
Sbjct: 24167 HGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKP 24226
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVE--YYRTGWNVWLKAITSRKTNV 431
D P + + + S + W+PPADDGG + NY+VE + G L + T
Sbjct: 24227 DKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTC 24286
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ +L E + Y FR+ A++ +G+S P SS V I
Sbjct: 24287 RIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVII 24321
Score = 154 bits (373), Expect = 2e-36
Identities = 112/400 (28%), Positives = 186/400 (46%), Gaps = 23/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PPGKP +++D NA T+ W DGG+P+ GY +E R + +W+R +
Sbjct: 11207 PSPPGKP----VVTDITENAATVSWTLPKSDGGSPITGYYME-RREVTGKWVRVNKTPIA 11261
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ +TGL + Y+FRV A N G S S SD + PP+ K L+D +
Sbjct: 11262 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPK-LKDKSR 11320
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGE 254
D V G SP + + + + +++ I DE F ++ +E
Sbjct: 11321 ETADLVWTKPLSDG-GSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYR 11379
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE------DGLLYEINETIFLKTTIVGKP 308
+ A N G + A + +P + E D + + +TI + + G+P
Sbjct: 11380 FRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRP 11439
Query: 309 TPTIEWRHDGHPIITDDRIE-ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P I W +G ++ + R++ I P+ L+I A R+D G+Y I AKN G + +
Sbjct: 11440 EPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRADHGKYIISAKNSSGHAQGSAI 11498
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR---TGWNVWLKAI 424
V V P P +N+ VT ++ T+ WE P D+GG ++ N+IVEY + GW++ +
Sbjct: 11499 VNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDV 11558
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T R +L+ +EY FR+ AE+ G+ +P+
Sbjct: 11559 TKRLIKA---NLLANNEYYFRVCAENKVGVGPTIETKTPI 11595
Score = 149 bits (361), Expect = 5e-35
Identities = 116/411 (28%), Positives = 172/411 (41%), Gaps = 21/411 (5%)
Query: 58 ASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQV 117
A + A + +K + P P G P + L+++ + L W DGG+P+ Y +
Sbjct: 10100 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNE---SCKLTWFSPEDDGGSPITNYVI 10156
Query: 118 ECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS 177
E W + R + GL Y FR+AA N +G + E S+ L +
Sbjct: 10157 EKRESDRRAWTPVTYTVT-RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI-- 10213
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIP----SPTIAWFKDDYEIFSSRRTAI 233
+EP +R ED+ E K +T++ S I + + I + + +
Sbjct: 10214 ----REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKV 10269
Query: 234 TTDESTS-VLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQYED 288
T D S + D E + +A N G TK C + + D
Sbjct: 10270 TNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD 10329
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L + E L GKP P + W D ++ DDR I TP L+ AKRSD
Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGN 407
G+Y + +N G V V P PP VS + + W+PP DDGG K+ N
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITN 10449
Query: 408 YIVEYYRTGWNVWLKAIT-SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
YI+E G +VW+ + S KT + L+EG +Y FRI AE+ YG+S P
Sbjct: 10450 YIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10500
Score = 147 bits (357), Expect = 2e-34
Identities = 111/397 (27%), Positives = 173/397 (43%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG PQ+ + D ++T+ W DGG+P+ GY VE W + +V
Sbjct: 14762 PGPPGTPQVTAVTKD----SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 14817
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+GL Y+FRV A N G S S+ S+ + PV +
Sbjct: 14818 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 14877
Query: 197 LENDKVE----FHVTFSGIPS---PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
L+ K E F +T + P W K ++ ++ + F I
Sbjct: 14878 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 14937
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I + + A+T R +EA PK++ +++D ++ + E L+ + G+P
Sbjct: 14938 NAAGAI--SPPSEPSDAIT-CRDDVEA-PKIKVDVKFKDTVILKAGEAFRLEADVSGRPP 14993
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PT+EW DG + ++EI I + L + R D G Y + A N G F V
Sbjct: 14994 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK 15053
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P PP ++VT + L W PP DDGG K+ +YIV+ T W + +
Sbjct: 15054 VLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQ 15113
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L++G+EY FR+ A + YG+ P ES PV
Sbjct: 15114 VTKLKVTKLLKGNEYIFRVMAVNKYGVGEP-LESEPV 15149
Score = 143 bits (347), Expect = 3e-33
Identities = 110/397 (27%), Positives = 167/397 (42%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P I D ++ ++W ++GG+P+ GY +E S W + I+
Sbjct: 16926 PGPPGTPFATAISKD----SMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIH 16981
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ LE +Y+FRV A N VG S+ S+ D P+ +KR E
Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT 17041
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ +G P W K + + ++ F I
Sbjct: 17042 LQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAK 17101
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I ++ G K + L P++ ++ D ++ ET L+ + GKP
Sbjct: 17102 NAAGAIS-KPSDSTGPITAKDEVEL---PRISMDPKFRDTIVVNAGETFRLEADVHGKPL 17157
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTIEW I R EI T ++L + A R D G+Y ++A N+ G + V
Sbjct: 17158 PTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVK 17217
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V VT + +L W PP DGG + +Y+VE T W +
Sbjct: 17218 VLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVV 17277
Query: 429 TN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
TN + + L+EG+EY FRI A + YG+ P ES+PV
Sbjct: 17278 TNSLKVTKLLEGNEYVFRIMAVNKYGVGEP-LESAPV 17313
Score = 143 bits (346), Expect = 3e-33
Identities = 111/397 (27%), Positives = 176/397 (44%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++ + S D ++ ++W DGG+ + GY +E S W++ +
Sbjct: 15844 PGPPGTP-VVTLSSRD---SMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIP 15899
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ + TGLE +Y+FRV+A N VG S++S+ D + + + R
Sbjct: 15900 QTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVT 15959
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + +T F I
Sbjct: 15960 LQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIAR 16019
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++ P++ +Y+D ++ E+ + I GKP
Sbjct: 16020 NAAGVFSEPSESTG--AIT-ARDEVDP-PRISMDPKYKDTIVVHAGESFKVDADIYGKPI 16075
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTI+W + R+EI T + L + A R D G Y ++AKN+ GE + V
Sbjct: 16076 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V ++ + TL W+PP DGG + NYIVE T VW + +
Sbjct: 16136 VLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16195
Query: 429 T-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L+EG+EY FRI A + YG+ P ES PV
Sbjct: 16196 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEP-LESEPV 16231
Score = 142 bits (343), Expect = 8e-33
Identities = 110/402 (27%), Positives = 166/402 (41%), Gaps = 23/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P++ I D ++ + WA DGG + GY +E W + +
Sbjct: 18405 PGPPSTPEVSAITKD----SMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRVAA N G SE S V + D P ++ D +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS-VFYRACDALYPPGPPSNPKVTDTSR 18519
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G +P + + E + T T F + E
Sbjct: 18520 SSVSLAWSKPIYDG-GAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18578
Query: 257 ---CTATNRG--------GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
C + G G V + R+ P++ ++ + T+ L TI
Sbjct: 18579 FRICAINSEGVGEPATLPGSVVAQERI---EPPEIELDADLRKVVVLRASATLRLFVTIK 18635
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P P ++W I+TD R +I +T F++L I + R D G Y + +N G TA
Sbjct: 18636 GRPEPEVKWEK-AEGILTD-RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAF 18693
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
V V P P N+++ SVTL WEPP DGG K+ NYIVE T +
Sbjct: 18694 VNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITN 18753
Query: 426 S-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ KT + +L EG Y FR+ A + YG+ P+ + PV++
Sbjct: 18754 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795
Score = 140 bits (340), Expect = 2e-32
Identities = 112/412 (27%), Positives = 182/412 (44%), Gaps = 28/412 (6%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P+ P ++ + D I + W DGG+P+ GY +E S W++ +
Sbjct: 12593 GVPSEPKNARVTKVNKD----CIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 12648
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V E GL +Y FR+ ALN G S S+ ++ +T R +PP + + DV
Sbjct: 12649 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA---RMPVDPPGKPEVI-DV 12704
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTA---ITTDESTSVLLF--- 244
T + G S I +F + ++ + TA I +E T+ L
Sbjct: 12705 TKSTVSLIWARPKHDG-GSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKA 12763
Query: 245 -HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+Q + + + VT L P++ + L + + L T
Sbjct: 12764 QYQFRAIARTAVNISPPSEPSDPVTI--LAENVPPRIDLSVAMKSLLTVKAGTNVCLDAT 12821
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP PT+ W+ DG + + I++++ L++ S R D G+Y I A+N G +
Sbjct: 12822 VFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 12881
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK- 422
A + V P PP +V + + L WEPP +DGG ++ NYIV+ T W +
Sbjct: 12882 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 12941
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGM-----SAPSSESSPVRIPGR 469
+ T T+ ++ LIEG EY+FRI AE+ YG+ + P+ +P PGR
Sbjct: 12942 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGR 12993
Score = 138 bits (334), Expect = 1e-31
Identities = 116/406 (28%), Positives = 174/406 (42%), Gaps = 26/406 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P I+ + D +++L W GG+P+ GY +E S W R +
Sbjct: 13679 PDAPPPPNIVDVRHD----SVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIR 13734
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +Y+FRV A+N G S S+ V+ + +P V VT
Sbjct: 13735 MRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT 13794
Query: 196 ALEND-KVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + K + +G P+ +W K ++ +T F
Sbjct: 13795 LIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAK 13854
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEA--APKLRYPRQYEDGLLYEINETIFLKT-TIVG 306
+ G I + + T+ +C + AP + +DGL + +TI L +I+G
Sbjct: 13855 NTAGAISAPSES------TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 13908
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
KP P W G I D +I+ TP S+L I A R D GEY I A N G
Sbjct: 13909 KPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHV 13968
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKA 423
VTV P PP V ++ + TL W PP +DGG + +YI+E T W V +
Sbjct: 13969 KVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED 14028
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I S + T LI+G+EY FR+ A + YG P +S PV++ R
Sbjct: 14029 IQSCRHVAT--KLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDR 14071
Score = 138 bits (333), Expect = 1e-31
Identities = 112/405 (27%), Positives = 183/405 (45%), Gaps = 28/405 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIV 135
P P P + ++D I + W P +GG+P+ GY VE +G+ +W+R + PI
Sbjct: 7784 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 7843
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
V G+ P +Y RV A+N +G S SE+S+ + V+ D + P D+
Sbjct: 7844 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCK--PTIDLETHDII 7900
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+E +K+ V F +P PT++W KD E+ +S R + D ++ L + + +D G
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 7960
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT--PTIE 313
T N+ G A + + P + D T G P +E
Sbjct: 7961 TITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLE 8020
Query: 314 WRHDGH----PIITDDRIEISITPKFSV------LKIHSAKRSDRGEYQIQAKN-IIGED 362
R G P+++ + ++S T K + ++ + + GEY I+ KN +I +D
Sbjct: 8021 RREAGRRTYIPVMSGEN-KLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQD 8078
Query: 363 TAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
PPDPP +V V +++T+ W+PP DGG K+ YI+E G W +
Sbjct: 8079 P-------KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR 8131
Query: 423 AITSRK--TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
T L EG EY+FR++AE+ G+S PS + P +
Sbjct: 8132 CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTK 8176
Score = 137 bits (332), Expect = 2e-31
Identities = 109/407 (26%), Positives = 169/407 (41%), Gaps = 16/407 (3%)
Query: 65 PRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K + +A P PPGKP++I + + ++L WA HDGG+ + GY VE +L
Sbjct: 12680 PSKPTEYVTARMPVDPPGKPEVIDVTK----STVSLIWARPKHDGGSKIIGYFVEACKLP 12735
Query: 124 STEWIR--TAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
+W+R TAP + + E TGLE +YQFR A V S SE SD +T+ ++
Sbjct: 12736 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12795
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ + +T V T G P PT++W KD + + + +
Sbjct: 12796 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT 12855
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D G+ TA N G A + L+ K P + +Y + +
Sbjct: 12856 LELFSVNRKDSGDYTITAENSSGS--KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWE 12913
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + + D + ++S T + + +++I A+N G
Sbjct: 12914 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGV 12973
Query: 362 DTAAFLVTVTA--PPDPPRNVS--VTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTG 416
F A P DPP V + K +T+ W+PPADDGG + Y++E T
Sbjct: 12974 GDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQ 13033
Query: 417 WNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K TL L EG+EY+FR+ A + G PS S
Sbjct: 13034 AVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDAS 13080
Score = 136 bits (328), Expect = 5e-31
Identities = 103/399 (25%), Positives = 179/399 (44%), Gaps = 21/399 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P + + + +IT+ W +GG+ + GY +E S W + ++
Sbjct: 20173 PGPPSTPWVTNVTRE----SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIR 20228
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+T + Y+FRV A N G S S+ VL + + EPP + R+ D++
Sbjct: 20229 TTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC----EPPRNV-RITDIS 20283
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLLFHQILPSDEGE 254
F G S + + ++ R T A T+ + + + + + + E
Sbjct: 20284 KNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYE 20342
Query: 255 IKCTATNRGGHAVTKARL-----CLEA--APKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ A N G + + C+++ P + P +Y + + Y ++ L+ I GK
Sbjct: 20343 FRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 20402
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PTIEW D + T+ + + T + + I A R + G Y+++ +N +G +A
Sbjct: 20403 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIR 20462
Query: 368 VTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAIT 425
V + P PP + + +TL W PPADDGG K+ +YIVE T VW + +
Sbjct: 20463 VQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEH 20522
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +T +I+G+EY FR++A + YG+ P S V
Sbjct: 20523 LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 20561
Score = 135 bits (327), Expect = 7e-31
Identities = 106/380 (27%), Positives = 170/380 (44%), Gaps = 20/380 (5%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+SD + + WAP +DGG+ + Y VE W T P V + +T L P
Sbjct: 12210 VSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-STVTPEVKKTSFHVTNLVPG 12268
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
++Y FRV A+N+ G +++ + S + +PP ++LE +N T
Sbjct: 12269 NEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPP---RKLEVTEMTKNS-----ATL 12320
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVL--LFHQILPSDEGE---IKCTATN 261
+ +P K D I S R D T SV+ L + EG+ + A N
Sbjct: 12321 AWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 12380
Query: 262 RGGHAVTK-ARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
G ++ + A EA +L P+ + + + + + ++ + GKP PT +W+
Sbjct: 12381 AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGED 12440
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++T + + S+L I R D G Y + A+N G DT V V P PP+
Sbjct: 12441 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12500
Query: 380 VSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLI 437
+D + +L W P +DGG + NYIVE W+ A+ S KT+ + LI
Sbjct: 12501 PFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLI 12560
Query: 438 EGSEYKFRIKAESPYGMSAP 457
G EY FR++AE+ +G+S P
Sbjct: 12561 PGQEYIFRVRAENRFGISEP 12580
Score = 134 bits (324), Expect = 2e-30
Identities = 117/397 (29%), Positives = 170/397 (42%), Gaps = 25/397 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPGKP +P+ + + +TLKWA + GG + Y VE L + W++ +L
Sbjct: 14862 PPGKP--VPL--NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 14917
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL Y+FRV A N G S SE SD +T D + + V +K + V
Sbjct: 14918 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILK 14977
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W KD E+ + + I + ++ L+ D G
Sbjct: 14978 AGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTL 15037
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHD 317
TATN GG A K ++ + P +G L + E K + P
Sbjct: 15038 TATNPGGFA--KHIFNVKVLDRPGPP----EGPL-AVTEVTSEKCVLSWFPPLDDGGAKI 15090
Query: 318 GHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIG-----EDTAAF 366
H I+ T ++ + V K+ K EY ++ A N G E
Sbjct: 15091 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15150
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V PPDPP+N VT S+ + W P DGG ++ NYIVE W+K
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15210
Query: 427 RKTNV--TLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ + L EG EY+FRI AE+ G+SAPS S
Sbjct: 15211 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 15247
Score = 133 bits (322), Expect = 3e-30
Identities = 116/431 (26%), Positives = 177/431 (41%), Gaps = 21/431 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + S+ ++ L W DGG+ + Y VE + S +W + +
Sbjct: 10813 PGPPRDLEV-SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 10871
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++Y FRVAA N G + E + PP + + DV E
Sbjct: 10872 FA-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEV 10929
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
V G SP + + E + T + ++ + + A
Sbjct: 10930 SLVWNKPDRDG-GSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTG-LQQGKTYRFRVKA 10987
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYED-----GLLYEINETIFLKTTIVGKPTPTIEW 314
N G + + +E KL P D GL+ + T+ I G P PT +W
Sbjct: 10988 ENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKW 11047
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
DG I TD+ + SVL I + R D GEYQI N G T A +TV P
Sbjct: 11048 TTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP 11107
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVT 432
PP +++ + +T+ W+PP DDGG V NYIVE T + W + + S KT +
Sbjct: 11108 GPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLK 11167
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSES--------SPVRIPGRAIDMDFLAVEARIIN 484
+ L +G EY FR++AE+ G+ P + SP PG+ + D + A ++
Sbjct: 11168 IPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAATVS 11226
Query: 485 EALTREDGEEP 495
L + DG P
Sbjct: 11227 WTLPKSDGGSP 11237
Score = 132 bits (320), Expect = 5e-30
Identities = 113/420 (26%), Positives = 171/420 (40%), Gaps = 17/420 (4%)
Query: 54 NHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR 113
NHY +P ++ K R PPG P+ P +S+ N T+ W DGG+ +
Sbjct: 14053 NHYGKG----EPVQSEPVKMVDRFGPPGPPEK-PEVSNVTKNTATVSWKRPVDDGGSEIT 14107
Query: 114 GYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
GY VE S W+R V +TGL+ Y+FRV+A N G SE SD +
Sbjct: 14108 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSV 14167
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
+ D A P + D T + G T + + ++
Sbjct: 14168 LMK-DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT-GYVVEHQKVGDEAWIKD 14225
Query: 234 TTDESTSVLLF--HQILPSDEGEIKCTATNRGG----HAVTKARLC-LEAAPKLRYPRQY 286
TT + + F + ++ + +A N G + + E AP +
Sbjct: 14226 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAEL 14285
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS 346
L+ +I + I G+P P + W D I +R I T F++L I R
Sbjct: 14286 RRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKNRANIENTESFTLLIIPECNRY 14343
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D G++ + +N G+ + V V P P N+ T SVTL W+ P DGG ++
Sbjct: 14344 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 14403
Query: 407 NYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
NYIVE + A T K + L EG EY FR+ AE+ YG+ P+ + PV+
Sbjct: 14404 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVK 14463
Score = 132 bits (320), Expect = 5e-30
Identities = 105/398 (26%), Positives = 168/398 (42%), Gaps = 19/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P + I D + ++W +DGG + GY +E S W++ +
Sbjct: 18008 PGPPGTPFVTSISKDQ----MLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 18063
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ TGL+ +Y+F+V+A N VG S++S+ D + + I R
Sbjct: 18064 DTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVT 18123
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + ++ F I
Sbjct: 18124 LKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIAR 18183
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++A P +Y+D ++ ET L+ I GKP
Sbjct: 18184 NAAGNFSEPSDSSG--AIT-ARDEIDA-PNASLDPKYKDVIVVHAGETFVLEADIRGKPI 18239
Query: 310 PTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W DG + T R+EI T + + L + R+D G+Y ++ N+ G + V
Sbjct: 18240 PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18299
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P PP + VT + L W PP DGG + +YI+E T W + T
Sbjct: 18300 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV 18359
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ N + L+ G+EY FR+ A + YG+ P ES PV
Sbjct: 18360 QALNYKVTKLLPGNEYIFRVMAVNKYGIGEP-LESGPV 18396
Score = 132 bits (318), Expect = 9e-30
Identities = 105/398 (26%), Positives = 167/398 (41%), Gaps = 15/398 (3%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P++ + D ++ + W DGG+ + GY +E W R ++
Sbjct: 16240 PDAPKAPEVTTVTKD----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIG 16295
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRV+A N G S S S PP K ++ +
Sbjct: 16296 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 16355
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G K D + T + + + ++L E +
Sbjct: 16356 SVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFR 16415
Query: 257 CTATNRGG---HAVTKARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
A N+ G HA + +E AP + + + ++ L I G+PTP
Sbjct: 16416 ICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTP 16475
Query: 311 TIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
++W + DG I D I I +T F+ L + + R D G+Y + +N G +A V
Sbjct: 16476 EVKWGKVDGE--IRDAAI-IDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVR 16532
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RK 428
V P PP N+ VT SV++ WEPP DGG K+ NYIVE + +T+ K
Sbjct: 16533 VLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHK 16592
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + L EG Y FR+ AE+ YG+ P+ + P+++
Sbjct: 16593 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV 16630
Score = 131 bits (317), Expect = 1e-29
Identities = 115/400 (28%), Positives = 169/400 (42%), Gaps = 25/400 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P+ + + D+ ++L W DGG+P+ GY VE G+ +WI+ V
Sbjct: 10912 PPGPPKDLHHVDVDKTE-VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT--VTNL 10968
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP---VFIKRLEDVT 195
E V+TGL+ Y+FRV A N VG L D + PP + +K +E +
Sbjct: 10969 ECVVTGLQQGKTYRFRVKAENIVGLG----LPDTTIPIECQEKLVPPSVELDVKLIEGLV 11024
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
V F G+P PT W D EI + + TD +SVL L D GE
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIE 313
+ T +N G L + P P +L E TI + +P I
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLDVPG---PPTGPINILDVTPEHMTISWQPPKDDGGSPVIN 11141
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV 368
+ + D +S + LKI ++ ++++A+N IG + T
Sbjct: 11142 YIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAK 11201
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TG-W-NVWLKAIT 425
+PP PP VT + + T+ W P DGG + Y +E TG W V I
Sbjct: 11202 HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIA 11261
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
K VT L EG+ Y+FR+ AE+ G+S PS S P++
Sbjct: 11262 DLKFRVT--GLYEGNTYEFRVFAENLAGLSKPSPSSDPIK 11299
Score = 131 bits (317), Expect = 1e-29
Identities = 113/399 (28%), Positives = 178/399 (44%), Gaps = 24/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP KP+I+ D IT+ W DGGAP+ GY VE + T+W +T+ +
Sbjct: 19587 PSPPSKPKIV----DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLR 19641
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLEDVT 195
E ++GL +Y FRV ++N VG S+ S+ SD ++ +R +E P+F I T
Sbjct: 19642 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP-QIAKER--EEEPLFDIDSEMRKT 19698
Query: 196 ALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ F +T F G P P + W K D ++ +R TTD TS L +D G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAYVDTTDSRTS-LTIENANRNDSG 19756
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPTPTI 312
+ T N ++ A L L L P + + ++ E+ L +
Sbjct: 19757 KYTLTIQN----VLSAASLTL-VVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 19811
Query: 313 EWRHDGHPIITDDRIEISITPKFSVL--KIHSAKRSDRGEYQIQAKNIIGEDTAAFL--- 367
+ + +S+T + L K+ + + +++ +N G A
Sbjct: 19812 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG 19871
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V +T P PP + VT SV+L W P DGG ++ +Y+VE G W+K ++
Sbjct: 19872 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 19931
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ + L E SEY FR+ AE+ G+S P PV I
Sbjct: 19932 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLI 19970
Score = 130 bits (314), Expect = 3e-29
Identities = 101/412 (24%), Positives = 168/412 (40%), Gaps = 15/412 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+ P++S+ + +T+ W P DGG+P+ GY +E + W + ++
Sbjct: 12990 PPGRCDP-PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIER 13048
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L TGL+ +Y+FRV A+N G S+ S + PP F K + D T
Sbjct: 13049 TLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPK-VYDTTRSS 13107
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGEIK 256
+ G SP I + + S ++ F ++ + + +
Sbjct: 13108 VSLSWGKPAYDG-GSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFR 13166
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYE------DGLLYEINETIFLKTTIVGKPTP 310
A N+ G++ + P + E L+ T+ L + G+P P
Sbjct: 13167 VYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP 13226
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W + ++I T + L+ + + D G+Y + +N G+ +V V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKT 429
P PP NV+V S + WEPP DGG + NY+V+ W T KT
Sbjct: 13287 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT 13346
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAIDMDFLAV 478
+ + +L EG Y FR+ AE+ YG+ P V+ PG +D+ +V
Sbjct: 13347 SFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSV 13398
Score = 130 bits (313), Expect = 3e-29
Identities = 101/387 (26%), Positives = 166/387 (42%), Gaps = 16/387 (4%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P PI+ D N++ +KW D G+P+ GY +E + ST W R ++
Sbjct: 8405 PPDAPDK-PIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNAL 8462
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+ + GL Y FRV A N G +S SD T + PP I R+ D ++
Sbjct: 8463 KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTDTSSTT 8520
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF--HQILPSDEGEIK 256
+ F+G + +F D ++ + + T++ V + +I + +++
Sbjct: 8521 IELEWEPPAFNG-GGEIVGYFVDK-QLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLR 8578
Query: 257 CTATNRGGHAVTKARLCLEAA-----PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+A N G + A P + + G+ +T+ + + G+P PT
Sbjct: 8579 VSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPT 8638
Query: 312 IEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
W + +G + DR+ I S L I A R D G Y I A N G AA V V
Sbjct: 8639 KVWTKEEGE--LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
P P ++ K L+W P DDGG ++ +I+E + W + I + ++
Sbjct: 8697 FDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSK 8756
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ L+EG EYKFR+ A++ +G P
Sbjct: 8757 CDITGLLEGQEYKFRVIAKNKFGCGPP 8783
Score = 129 bits (312), Expect = 5e-29
Identities = 105/402 (26%), Positives = 174/402 (43%), Gaps = 22/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P++ I N++T+ W+ DGG+ + GY +E S W + +
Sbjct: 20569 PGPPGIPEVTKITK----NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 20624
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+TGL YQ+RV A+N G +SE S+ + PP I R+ D T
Sbjct: 20625 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKI-RIADSTK 20683
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT--DESTSVLLFHQILPSDEGE 254
+ G S + + + T ++T + T+ + + P
Sbjct: 20684 SSITLGWSKPVYDG-GSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYY 20742
Query: 255 IKCTATNRGGHAV-------TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ +A N G +A+ LEA P++ ++ + E + + G+
Sbjct: 20743 FRVSAVNCAGQGEPIEMNEPVQAKDILEA-PEIDLDVALRTSVIAKAGEDVQVLIPFKGR 20801
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ WR D + +D R I T S+L I R+D G+Y + +N +GE ++ +
Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861
Query: 368 -VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P + + V +VTL W+PP DGG + NY++E W ++ S
Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTW--SVVS 20919
Query: 427 RKTNVTLFDLIEGSE---YKFRIKAESPYGMSAPSSESSPVR 465
K + T F LI+ SE + FR+ AE+ G+ P + PV+
Sbjct: 20920 HKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK 20961
Score = 128 bits (310), Expect = 8e-29
Identities = 119/462 (25%), Positives = 193/462 (41%), Gaps = 36/462 (7%)
Query: 65 PRKNVHWKSA-GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K V K +P+PP P+ I D N++ L W P HDGG+ + GY VE ++G
Sbjct: 10603 PSKPVFAKDPIAKPSPPVNPEAI----DTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG 10658
Query: 124 STEWIRT--APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
EW R P + +TGL Y+FRV A+N G S+ + + + + V DR
Sbjct: 10659 DEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRL- 10716
Query: 182 QEPPVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
EPP I + D + G+P P + W K+D + + R +T
Sbjct: 10717 -EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVT--PV 10773
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
S L D G T N G ++ + P PR E + + + +
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP--GPPRDLEVSEIRKDSCYL 10831
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE---YQIQA 355
K + + + + + + +S T K K H AK + G +++ A
Sbjct: 10832 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK---KKSHFAKHLNEGNQYLFRVAA 10888
Query: 356 KNIIGE----DTAAFLVTVTA--PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNY 408
+N G +T + + PP PP+++ VDK+ V+L W P DGG + Y
Sbjct: 10889 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEVSLVWNKPDRDGGSPITGY 10947
Query: 409 IVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV---- 464
+VEY G W+K T + L +G Y+FR+KAE+ G+ P + + P+
Sbjct: 10948 LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 11006
Query: 465 RIPGRAIDMDFLAVEARIINEALTREDGEEPRISPAPRRKRT 506
++ ++++D +E ++ T R P P K T
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT 11048
Score = 128 bits (309), Expect = 1e-28
Identities = 97/377 (25%), Positives = 156/377 (41%), Gaps = 17/377 (4%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++TL W P DGGA + Y VE R + + T + + L+ Y FR
Sbjct: 18716 DSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFR 18774
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSP 214
V A N+ G +E ++ + VS EPP+ R+ V N
Sbjct: 18775 VLASNEYGIGLPAETTEPVKVS------EPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18828
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA------VT 268
I + + + S + + T T + +E + A N G + V
Sbjct: 18829 KITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP 18888
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+E P + P + + E + + G+P T+ WR DG + R+
Sbjct: 18889 VIARDIEIKPSVELPFHTFN---VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 18945
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
+S + + L I A + D G Y++ N G T + V P PP + +
Sbjct: 18946 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 19005
Query: 389 SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVTLFDLIEGSEYKFRIK 447
S+T+ W PP DGGC++ NYIVE T W + + +T++ + L GSEY+FR+
Sbjct: 19006 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 19065
Query: 448 AESPYGMSAPSSESSPV 464
AE+ YG S+ S S+ V
Sbjct: 19066 AENRYGKSSYSESSAVV 19082
Score = 127 bits (307), Expect = 2e-28
Identities = 73/191 (38%), Positives = 97/191 (50%), Gaps = 2/191 (1%)
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
+ AP++ + GL + I L T+ GKP P I W + D RI I PK
Sbjct: 7188 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 7247
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW 394
S + I +KRSD G Y I+A N+ G TA V V P PP +T ++S L W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PP DDGG K+ NY+VE T VW K + T + TN LI EY FR+ AE+ YG
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7367
Query: 454 MSAPSSESSPV 464
+ P ++SP+
Sbjct: 7368 VGEP-VQASPI 7377
Score = 127 bits (306), Expect = 2e-28
Identities = 108/398 (27%), Positives = 168/398 (42%), Gaps = 19/398 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ RP PPGK ++ + N+++L W HDGG+ + GY VE GS +W A
Sbjct: 15547 KASERPLPPGKITLMDVTR----NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA 15602
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V E +TGL +Y FRV+A N+ G S+ +LS V ++ D PP F
Sbjct: 15603 TVKVT--EATITGLIQGEEYSFRVSAQNEKGISDPRQLS-VPVIAKDLVI--PPAFKLLF 15657
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
T L + ++ V F G P+P + W KD+ + + R + E+ S+L D
Sbjct: 15658 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRED 15717
Query: 252 EGEIKCTATNRGGHAV-TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G TN G A+ T + L+ P + ++ I T+ +
Sbjct: 15718 VGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSI--TLSWGPPKYDGGSS 15775
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ + T +S T + +K K +++I A+N G+ T
Sbjct: 15776 INNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPT 15835
Query: 371 TAP-----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
A P PP VT S+ + W P DGG +V Y +E +W+K
Sbjct: 15836 VAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNK 15895
Query: 426 S--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ +T L EG EY+FR+ AE+ G+ PS S
Sbjct: 15896 TPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Score = 127 bits (306), Expect = 2e-28
Identities = 101/393 (25%), Positives = 175/393 (44%), Gaps = 17/393 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP ++ I D ++++ W P DGG+ ++ Y VE R + +
Sbjct: 16537 PSPPVNLKVTEITKD----SVSITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCH 16591
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ + L+ Y FRV A N+ G ++ +D + V+ +PP I ++DVT
Sbjct: 16592 KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKIT-VDDVTR 16647
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
G S I + + S + + +S ++ + + +E +
Sbjct: 16648 NSVSLSWTKPEHDG-GSKIIQYIVEMQAKHSEKWSECARVKSLQAVITN-LTQGEEYLFR 16705
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL---YEINETIFLKTTIVGKPTPTIE 313
A N G + ++ A L + ++ + + ++ I G+P PTI
Sbjct: 16706 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTIT 16765
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG P+ RI ++ + + L I + D G+Y I N++G+ TA+ +
Sbjct: 16766 WTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 16825
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
PDPP+ V +S+TL W PP GGC++ NYIV+ T VW + + T +T +
Sbjct: 16826 PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL 16885
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L G+EY+FRI AE+ YG S + ES P+
Sbjct: 16886 KVTKLKTGTEYQFRIFAENRYGQSF-ALESDPI 16917
Score = 126 bits (304), Expect = 4e-28
Identities = 108/397 (27%), Positives = 165/397 (41%), Gaps = 19/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP I + SD ++L W +DGG+ + G+ VE S W + +
Sbjct: 21260 PGPPGKPVIYNVTSD----GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 21315
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E TGL YQFRV A N G S+ S+ S S P +I DVT
Sbjct: 21316 GREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI----DVTR 21371
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E ++++ S + + + + TD S + P D E +
Sbjct: 21372 -ETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFR 21430
Query: 257 CTATNRGGHAVTKARLC-------LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
A N G ++ P + + +Y DGL+ + E++ +K + G+P
Sbjct: 21431 IIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPV 21490
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P + W DG I +EI+ + L + A R RG Y ++AKN G A V
Sbjct: 21491 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 21550
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSR 427
V P + T + +TL W+ P +DG + +YI+E T W L
Sbjct: 21551 VQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCE 21610
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T LI G+EY+FR+ A + +G+ P +S PV
Sbjct: 21611 AQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPV 21646
Score = 125 bits (302), Expect = 7e-28
Identities = 105/402 (26%), Positives = 167/402 (41%), Gaps = 25/402 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+ P +P++ + + NA++++W HDGG+ + GY VE + W++ L
Sbjct: 22344 PSAPTRPEVYHVSA----NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCL 22399
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPPVF------IK 189
+TGL +YQFR ALN G S SE S ++ + A P V +
Sbjct: 22400 ECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVS 22459
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
+ A + P + W K +Y I S +T F
Sbjct: 22460 LIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRV 22519
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYP-RQYEDGLLYEINETIFLKTT 303
+ + G I + + G VT C + A PK R + D + + L
Sbjct: 22520 LAKNAAGVISKGSESTG--PVT----CRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAA 22573
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP P I W + +++ + T K + I RSD G+Y + KN G
Sbjct: 22574 VGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKA 22633
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ +V V P P ++V+R + TL W P +DGG ++ +YIVE T W+
Sbjct: 22634 VSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIV 22693
Query: 424 ITSRKT-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + LI+ +EY FR++A + YG P ES P+
Sbjct: 22694 EGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVP-VESEPI 22734
Score = 125 bits (301), Expect = 1e-27
Identities = 110/402 (27%), Positives = 178/402 (44%), Gaps = 24/402 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
RP+PP + SD +++ LKW P DGG+P+ GY +E G WIR +V
Sbjct: 6794 RPSPP----VNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLV 6849
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+TGLE +KY +RV+A N G S+ SE+ LT +D A EP + + +D +
Sbjct: 6850 PELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLT--ADDAFVEPTMDLSAFKDGL 6907
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ + + V +G P PT W D + + R + T + + L+ SD+G
Sbjct: 6908 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 6967
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TI 312
NR + + + A P ++ D ++ T G P +
Sbjct: 6968 YTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVV 7027
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VT 369
E R T ++ +F+V + K +++ A+N G A++ V
Sbjct: 7028 EKREVSRKTWT-KVMDFVTDLEFTVPDLVQGKEY---LFKVCARNKCGPGEPAYVDEPVN 7083
Query: 370 VTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL---KA 423
++ P PDPP NV + S+ L W+PP +DGG ++ YIVE G + W+ +
Sbjct: 7084 MSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP 7143
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ K VT L EG Y +R+KA + G S PS + ++
Sbjct: 7144 VAETKMEVT--GLEEGKWYAYRVKALNRQGASKPSRPTEEIQ 7183
Score = 125 bits (301), Expect = 1e-27
Identities = 106/401 (26%), Positives = 173/401 (43%), Gaps = 20/401 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPP-IV 135
P+PPG P+ + + I ++W DGG + Y V+ S W R +V
Sbjct: 22743 PSPPGIPEEVGTGKEH----IIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22798
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +T L YQFRV A+N G+S SE S+ ++ + PP R+ D T
Sbjct: 22799 YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPS-APRVVDTT 22857
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEG 253
+ G + + + + E + + + T+ + F + +
Sbjct: 22858 KHSISLAWTKPMYDG-GTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKY 22916
Query: 254 EIKCTATN-RGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEIN----ETIFLKTTIVGK 307
+ A N +G +++ +E ++ P + D L + ++ L ++ G+
Sbjct: 22917 SFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGR 22976
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P I W G + + R I T +S+L + R D G+Y I+A+N G+ +A L
Sbjct: 22977 PPPVITWSKQGIDLAS--RAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVL 23034
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V V P P +V V SVT+ WE P DGG V NYIVE + K +T++
Sbjct: 23035 VKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAF-KTVTTK 23093
Query: 428 --KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
KT + L+EG+ Y FR+ E+ YG+ P S V +
Sbjct: 23094 CSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLV 23134
Score = 124 bits (299), Expect = 2e-27
Identities = 104/397 (26%), Positives = 171/397 (43%), Gaps = 18/397 (4%)
Query: 71 WKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT 130
+K+A PPG P I I +D ++ITL W+ +DGG+ + GY VE + EW
Sbjct: 20661 YKAADPIDPPGPPAKIRI-ADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTV 20719
Query: 131 APPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
+ +R E V++ L+P Y FRV+A+N G E+++ + + E + +
Sbjct: 20720 STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
V A + V+ + F G P PT+ W KD+ + S R +I +S+S+L Q+
Sbjct: 20780 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 20839
Query: 250 SDEGEIKCTATNRGGH----AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+D G+ T N G V+ L AA + + G + T+ ++
Sbjct: 20840 NDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV-----TLLWDPPLI 20894
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG----- 360
+P I + + +S + K+ +++ A+N IG
Sbjct: 20895 DGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC 20954
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
E T V P P R++S+ SV L W P DGG + Y+VE G W
Sbjct: 20955 ETTEP--VKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW 21012
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
A S+ + + L E S +FR+ A++ G+S P
Sbjct: 21013 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 21049
Score = 124 bits (298), Expect = 2e-27
Identities = 102/393 (25%), Positives = 168/393 (42%), Gaps = 20/393 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + + + +A + W P DGG+P+ Y V+ W T +
Sbjct: 13290 PGPPVNVTVKEISKDSAY-VTWEPPIIDGGSPIINYVVQKRDAERKSW-STVTTECSKTS 13347
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ LE Y FRV A N+ G + E D + +ASQ P PV ++ V+
Sbjct: 13348 FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAV-----KASQTPGPVVDLKVRSVSK-S 13401
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S S I + D + ++ + S + E + +
Sbjct: 13402 SCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRVMKSLSLQYSA-KDLTEGKEYTFRVS 13459
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL-----LYEINETIFLKTTIVGKPTPTIE 313
A N G T + + + A + P GL L + N LK I GKP P++
Sbjct: 13460 AENENGEG-TPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 13518
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W+ P+ TD R+ + + + L ++ ++SD G+Y I KN+ G + V
Sbjct: 13519 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 13578
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNV 431
P P + +++TL W PP DDGG ++ NYI+E + N W+ ++ +KT
Sbjct: 13579 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 13638
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L EG EY FR+ AE+ YG+ +S P+
Sbjct: 13639 RVTRLHEGMEYTFRVSAENKYGV-GEGLKSEPI 13670
Score = 124 bits (298), Expect = 2e-27
Identities = 112/426 (26%), Positives = 181/426 (42%), Gaps = 43/426 (10%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR- 137
PPG P P ++D + +L W +DGG + GY VE ++G WI+ LR
Sbjct: 14175 PPGPPSN-PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI 14233
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKRLEDVTA 196
+ V+ L+ KY FR++A+ND G + + DV V + A E ++R V A
Sbjct: 14234 TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA 14293
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V G P+P + W KD+ + R I ES ++L+ + D G+
Sbjct: 14294 --GLSIRIFVPIKGRPAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFV 14349
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
T N G + + P + L+ T + K + T+ W
Sbjct: 14350 MTIENPAGKKSGFVNVRVLDTP----------------GPVLNLRPTDITKDSVTLHWDL 14393
Query: 317 ---DGHPIITDDRIEISITPKFS----VLKIHSAKRSDRG-----EY--QIQAKNI--IG 360
DG IT+ +E + S K H G EY ++ A+N IG
Sbjct: 14394 PLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIG 14453
Query: 361 EDTAAFL-VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
E T V + P PP ++++ +V+L W P DGG K+ Y++E R G +
Sbjct: 14454 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14513
Query: 420 WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI--DMDFLA 477
W T + + +L EG EY F++ A + G SAP ES PV + + + ++D
Sbjct: 14514 WTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRG 14572
Query: 478 VEARII 483
+ +++
Sbjct: 14573 IYQKLV 14578
Score = 124 bits (298), Expect = 2e-27
Identities = 101/391 (25%), Positives = 172/391 (43%), Gaps = 19/391 (4%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH 149
+D +++TL W DGG+ + Y VE R + + TA + +TGL
Sbjct: 14380 TDITKDSVTLHWDLPLIDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGC 14438
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+Y FRV A N+ G +E ++ + S + PP + + D+T
Sbjct: 14439 EYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLN-IMDITKSTVSLAWPKPKHD 14494
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G S + + S + T ITT + ++ + +E + A N G + +
Sbjct: 14495 G-GSKITGYVIEAQRKGSDQWTHITTVKGLECVV-RNLTEGEEYTFQVMAVNSAGRSAPR 14552
Query: 270 AR---LCLEAA--PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
+ E P+L Y+ ++ + + I ++ ++G+P PT+ W+ +
Sbjct: 14553 ESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQT 14612
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR 384
R+ T ++L I+ RSD G Y + A+NI+GE + V P PP
Sbjct: 14613 QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFD 14672
Query: 385 QVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEY 442
+V VT W+PP +DGG + NY+VE +T W++ A T +T L G EY
Sbjct: 14673 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEY 14732
Query: 443 KFRIKAESPYGM-----SAPSSESSPVRIPG 468
+FR+KA++ YG+ SA + P ++PG
Sbjct: 14733 QFRVKAQNRYGVGPGITSACIVANYPFKVPG 14763
Score = 123 bits (296), Expect = 4e-27
Identities = 102/392 (26%), Positives = 167/392 (42%), Gaps = 21/392 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP ++ I D ++T+ W DGG+ + GY VE WI+ +
Sbjct: 17322 PGPPKSLEVTNIAKD----SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRIT 17377
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H+Y+FRV+A N G S + V + D + P + D T
Sbjct: 17378 DLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT-VYYKACDPVFKPGPPTNAHIVDTTK 17436
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEGE 254
+ G S + + + + +T V F ++ E +
Sbjct: 17437 NSITLAWGKPIYDG-GSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYK 17495
Query: 255 IKCTATNRGG-------HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
I+ A N+ G K LEA P+L + G++ + + G+
Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAGGSARIHIPFKGR 17554
Query: 308 PTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
PTP I W R +G D+++I ++ L I + R+D G+Y ++ +N G +A
Sbjct: 17555 PTPEITWSREEGE---FTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 17611
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P PP+N++V S L WEPP DGG KV NY+++ + + +
Sbjct: 17612 TVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSK 17671
Query: 427 -RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
KT+ + +L EG+ Y FR+ AE+ +G+ P
Sbjct: 17672 CSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 17703
Score = 123 bits (296), Expect = 4e-27
Identities = 110/397 (27%), Positives = 158/397 (39%), Gaps = 20/397 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + I D + +TL W P DGG+ + GY VE + + W+R V
Sbjct: 23435 PGPPETLQIF-DVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTR 23493
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
TGL +Y+ RV A+N G S S + A P R+ D T
Sbjct: 23494 YRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQN-PRVTDTTRTSV 23552
Query: 200 D---KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEI 255
V S + I K D ++ T T + L H LP E
Sbjct: 23553 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNT--TPTKIREYTLTH--LPQGAEYRF 23608
Query: 256 KCTATNRGGHAV-TKARLCLEAAPKLRYP-----RQYEDGLLYEINETIFLKTTIVGKPT 309
+ A N GG + ++ L YP +Y++G+ I L I GKP
Sbjct: 23609 RVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPF 23668
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P +W +G I R I+ + + L I A R D G Y + +N G+ V
Sbjct: 23669 PICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVR 23726
Query: 370 VTAPPDPPRNVSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P+ P + +SV + W PPADDGG + YI+E W + R
Sbjct: 23727 VIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVR 23786
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T++ + L E EY FR+ AE+ +G+S P PV
Sbjct: 23787 GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPV 23823
Score = 122 bits (295), Expect = 5e-27
Identities = 109/402 (27%), Positives = 167/402 (41%), Gaps = 24/402 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + ++TL W P DGG+ ++ Y VE R + + T +
Sbjct: 15455 PGPPQDLKV-KEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCHKTS 15512
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L+ Y FRV A N+ G +E T S +AS+ P P L DVT
Sbjct: 15513 WKVDQLQEGCSYYFRVLAENEYGIGLPAE-----TAESVKASERPLPPGKITLMDVTR-N 15566
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S + + + S + T + T + ++ +E + +
Sbjct: 15567 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG-LIQGEEYSFRVS 15625
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKPTPTIE 313
A N G + + A L P ++ LL+ E + + +G+PTP +
Sbjct: 15626 AQNEKGISDPRQLSVPVIAKDLVIPPAFK--LLFNTFTVLAGEDLKVDVPFIGRPTPAVT 15683
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W D P+ R+ T S+L I A R D G Y ++ N GE V V
Sbjct: 15684 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
P PP V + S+TL W PP DGG + NYIVE T W + + T +T +
Sbjct: 15744 PGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTI 15803
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSA-----PSSESSPVRIPG 468
L G EY+FRI AE+ YG S P+ P ++PG
Sbjct: 15804 KACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPG 15845
Score = 122 bits (294), Expect = 7e-27
Identities = 87/391 (22%), Positives = 161/391 (41%), Gaps = 8/391 (2%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P ++ + +D ++L+W+ DGG + GY +E + +W + ++
Sbjct: 21756 PPGPPTVVKV-TDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT 21814
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+T L+ +Y+FRV+A+N G + E++ + + E + +
Sbjct: 21815 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRA 21874
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + G P+PT W K D + S R I T +S S L +D G+ T
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLT 21932
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
N G + + P P ++D + + T+ ++ + +
Sbjct: 21933 VENNSGSKSITFTVKVLDTPGPPGPITFKD--VTRGSATLMWDAPLLDGGARIHHYVVEK 21990
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VTVTAPPD 375
IS + K++ +++ A N G + + T P
Sbjct: 21991 REASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 22050
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD 435
PPR + V S L W P DGG ++ Y++E + G + W++A +++ T+
Sbjct: 22051 PPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVER 22110
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
L+E +EY+FR+KA++ G S P S V I
Sbjct: 22111 LVEKTEYEFRVKAKNDAGYSEPREAFSSVII 22141
Score = 122 bits (293), Expect = 9e-27
Identities = 96/402 (23%), Positives = 161/402 (40%), Gaps = 11/402 (2%)
Query: 68 NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW 127
+V +++ PPG P P ++D ++++L W+ +DGGAP++GY VE + EW
Sbjct: 18494 SVFYRACDALYPPGPPSN-PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 18552
Query: 128 IRTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
PP L+ + +T L+ +Y FR+ A+N G + L + V+ +R
Sbjct: 18553 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSV-VAQERIEPPEIE 18611
Query: 187 FIKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
L V L + + VT G P P + W K E + R I S ++L+
Sbjct: 18612 LDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSSFTMLVID 18669
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ D G T N G + + +P P + + + T+ + ++
Sbjct: 18670 NVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--PVNLTIREVKKDSVTLSWEPPLI 18727
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
+ + I+ + +I + + +++ A N G A
Sbjct: 18728 DGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA 18787
Query: 366 FL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
V V+ PP PP V++ + T+ WE P DGG K+ Y+VE G W
Sbjct: 18788 ETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18847
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T+ L G EY FR+ A + G S P PV
Sbjct: 18848 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 18889
Score = 121 bits (291), Expect = 2e-26
Identities = 97/398 (24%), Positives = 171/398 (42%), Gaps = 17/398 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVL 136
APPGKPQ P ++D +++L W+ +GG+ + GY +E ++ EW + P +
Sbjct: 23534 APPGKPQN-PRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23592
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R E LT L +Y+FRV A N G +E+ + V+ + + + E +
Sbjct: 23593 R-EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFV 23651
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ + + G P P W K+ +I S+R I T E+ + L+ + D G
Sbjct: 23652 RQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYD 23709
Query: 257 CTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
N+ G ++ + +P P +Y+D + + + + + +
Sbjct: 23710 LVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVR--VSWRPPADDGGADILGYI 23767
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG------EDTAAFLVT 369
+ + I + + L + K + +++ A+N G + T
Sbjct: 23768 LERREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKT 23827
Query: 370 VTAPPDPPRNVSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
PP+PP N V K SV+L W P DDGG +V Y +E T + W++ ++
Sbjct: 23828 PLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQI 23887
Query: 429 TNV--TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T T+ L+ +EY+FRI A++ G+S S S PV
Sbjct: 23888 TTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPV 23925
Score = 120 bits (289), Expect = 3e-26
Identities = 104/398 (26%), Positives = 166/398 (41%), Gaps = 22/398 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + +A L W P DGGA ++ Y ++ R + + +
Sbjct: 17619 PGPPQNLAVKEVRKDSAF-LVWEPPIIDGGAKVKNYVID-KRESTRKAYANVSSKCSKTS 17676
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L Y FRV A N+ G V TV + +A++ P P L DV+
Sbjct: 17677 FKVENLTEGAIYYFRVMAENEFGVG-----VPVETVDAVKAAEPPSPPGKVTLTDVSQTS 17731
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ G + + + + + + +I + + + E + +
Sbjct: 17732 ASLMWEKPEHDG--GSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVK 17789
Query: 259 ATNRGGHA------VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
A N G + V L P L+ P + E + ++ ++G+P P I
Sbjct: 17790 AYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIPVIGRPRPNI 17846
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ R+ + T +VL I + D G+Y + A N G T V V
Sbjct: 17847 SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE 17906
Query: 373 PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTN 430
P PP +V V + WEPPA GGC++ NYIVE T W + + T +T
Sbjct: 17907 KPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT 17966
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVRIP 467
+ + L G+EY+FRI AE+ YG SAP S++ V+ P
Sbjct: 17967 IKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYP 18004
Score = 120 bits (288), Expect = 4e-26
Identities = 106/409 (25%), Positives = 170/409 (41%), Gaps = 23/409 (5%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP P++ I D ++ + W DGG+ + Y VE WI+
Sbjct: 15156 GPPDPPKNPEVTTITKD----SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 15211
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKR 190
+ ++GL H+Y+FR+ A N G S S S TV P V
Sbjct: 15212 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTS 15271
Query: 191 LEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
++ N + + +G +D+++I + T + + L +Q
Sbjct: 15272 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQ--- 15328
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE-DGLLYEINE-----TIFLKTT 303
E +I+ A N G A P + E D L ++ T+ L
Sbjct: 15329 --EYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP 15386
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
I G+P P ++W D + D+ I T +++L + + R D G+Y + +N G +
Sbjct: 15387 IKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKS 15444
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
A V V P PP+++ V SVTL W+PP DGG K+ NYIVE + +
Sbjct: 15445 AFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV 15504
Query: 424 ITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI 471
T+ KT+ + L EG Y FR+ AE+ YG+ P+ + V+ R +
Sbjct: 15505 ATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL 15553
Score = 119 bits (286), Expect = 6e-26
Identities = 106/396 (26%), Positives = 172/396 (43%), Gaps = 21/396 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG Q + + + + N T+ W +GG+ + + VE + W A + R
Sbjct: 11505 PGPCQNLKVTNVTKENC-TISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR-- 11561
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL-SDVLTVSS-DRASQEPPVFIK-RLEDVTA 196
L+ L ++Y FRV A N VG E + +L ++ DR + + I + +
Sbjct: 11562 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 11621
Query: 197 LENDKVEFHVTFSGIPSPTIAWFK--DDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L+ + ++ + K DD+E R + + T ++ + + + E
Sbjct: 11622 LKWRRPDYDGGSPNLSYHVERRLKGSDDWE-----RVHKGSIKETHYMV-DRCVENQIYE 11675
Query: 255 IKCTATNRGGHA---VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+ N GG + T+ + E K + L + +TI L+ + GKP P
Sbjct: 11676 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 11735
Query: 312 IEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ W D + R++I S + AKRSD G+Y + A N G A V
Sbjct: 11736 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 11795
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRK 428
V P P RN+ + T+ W+PP DDGGC++ NYI+E T VW + T
Sbjct: 11796 VLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 11855
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ LIEG+EY FR++AE+ G + P +ES PV
Sbjct: 11856 PGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPV 11890
Score = 118 bits (285), Expect = 9e-26
Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 14/385 (3%)
Query: 91 DDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHK 150
D N+I L W P +DGG+ ++GY VE GS +W+ P+ ++ +TGLE
Sbjct: 7101 DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKW 7159
Query: 151 YQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSG 210
Y +RV ALN G S S ++ + + + E + +K L +T K+E T +G
Sbjct: 7160 YAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTG 7219
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W K D + +R I S + SD G A N G A A
Sbjct: 7220 KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT--A 7277
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI--E 328
+ + K P ++ + NE+ L + + TD + +
Sbjct: 7278 VVEVNVLDKPGPPAAFD--ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 7335
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT---APPDPPRNVSVT 383
+S T K + K + +++ A+N+ +GE A +T PP PP + +
Sbjct: 7336 LSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPS 7395
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSE 441
+VTL W P DDGG + Y VE + W++ + + T + L +
Sbjct: 7396 DITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKK 7455
Query: 442 YKFRIKAESPYGMSAPSSESSPVRI 466
Y+FR+ AE+ G PS + P+ I
Sbjct: 7456 YRFRVLAENLAGPGKPSKSTEPILI 7480
Score = 118 bits (285), Expect = 9e-26
Identities = 86/381 (22%), Positives = 166/381 (43%), Gaps = 11/381 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + ++ D + LKW P +DGG P++ Y +E T W++
Sbjct: 7687 PGPPYALAVV-DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7745
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + + QF+V A N+ G + SE +++L++ + PP+ + + ++
Sbjct: 7746 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTD--AGRKH 7803
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD--ESTSVLLFHQILPSDEGEIKC 257
+ + SP I + + + + + + + + + ++P E ++
Sbjct: 7804 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 7863
Query: 258 TATNRGG----HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
A N G +++ + + K + D ++ E E + + P PT+
Sbjct: 7864 RAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE-GEKLSIPVPFRAVPVPTVS 7922
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG + DR+ + + L++ + R+D G Y I +N +G TA+ V V
Sbjct: 7923 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTNVT 432
P P +++ + S L WEPP DGG + +Y++E G ++ ++ K + T
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8042
Query: 433 LFDLIEGSEYKFRIKAESPYG 453
+ DLI EY FR+KA + G
Sbjct: 8043 VKDLIPNGEYFFRVKAVNKVG 8063
Score = 118 bits (284), Expect = 1e-25
Identities = 104/394 (26%), Positives = 159/394 (40%), Gaps = 25/394 (6%)
Query: 86 IPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIVLRPELVLTG 144
IP S+ N+ITL WA DGG+ ++ Y +E ST W++ + + +TG
Sbjct: 21660 IPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21719
Query: 145 LEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED---VTALENDK 201
L ++Y+F V A N G S +S ++ PP +K + +LE K
Sbjct: 21720 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21779
Query: 202 VEFHVTFSGI-------PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
F I + W K + E R +T ++ F + G+
Sbjct: 21780 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGK 21839
Query: 255 -IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C T G RL AP+L ++ + +I L G+PTPT
Sbjct: 21840 GDSCEVT---GTIKAVDRL---TAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAV 21893
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W + R +I T FS L + + R+D G+Y + +N G + F V V
Sbjct: 21894 WSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDT 21951
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P PP ++ S TL W+ P DGG ++ +Y+VE W + S K +
Sbjct: 21952 PGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW--QVISEKCTRQI 22009
Query: 434 F---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
F DL EG Y FR+ A + YG+ P P+
Sbjct: 22010 FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 22043
Score = 118 bits (283), Expect = 1e-25
Identities = 98/396 (24%), Positives = 161/396 (40%), Gaps = 14/396 (3%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + I +D ++L W P +DGGA + Y +E S W
Sbjct: 6694 PGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLS 6752
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + +Y FRV A N +G S + + V+ PPV + + +
Sbjct: 6753 ATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQ 6812
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IK 256
K E + G SP + + + E + I + L +++ ++G +
Sbjct: 6813 LKWEPPLKDGG--SPILGYIIERCE--EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYR 6868
Query: 257 CTATNRGGHAVTKARLC-LEAAPKLRYPRQ----YEDGLLYEINETIFLKTTIVGKPTPT 311
+A N+ G + L L A P ++DGL + I + G P PT
Sbjct: 6869 VSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPT 6928
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
W + T DR+++ ++ L I ++RSD+G Y ++ +N + + V V
Sbjct: 6929 ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 6988
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTN 430
A P P+ + SV L WEPP DDGG + Y+VE W K +
Sbjct: 6989 ARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLE 7048
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ DL++G EY F++ A + G P+ PV +
Sbjct: 7049 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 7084
Score = 118 bits (283), Expect = 1e-25
Identities = 104/406 (25%), Positives = 169/406 (41%), Gaps = 33/406 (8%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP+++ ++ + W P +GG+P+ GY +E GS W R + +
Sbjct: 9102 PGPPGKPKVLARTK----GSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPIT 9157
Query: 137 RPELVLTGLEPPH-----KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ L P KYQFR A+N G SE SD V+ D P +
Sbjct: 9158 KVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP-EVAGDPIFPPGPPSCPEV 9216
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE---STSVLLFHQIL 248
+D T + + + SP + + E ++ + + +T + +
Sbjct: 9217 KDKTK-SSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLK 9275
Query: 249 PSDEGEIKCTATNRGGHAV---TKARLC---LEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + A N G + T + ++ P++ +D L+ + I +
Sbjct: 9276 ELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA 9335
Query: 303 TIVGKPTPTIEWRHDG----------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I G+PTP W DG H I D ++E + SV+ I KRS G+Y
Sbjct: 9336 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA--ENSSVIIIPECKRSHTGKYS 9393
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
I AKN G+ TA V V P PP+++ V+ S L W+ P DDGG ++ Y++E
Sbjct: 9394 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 9453
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W K T + DL+ +Y FR++AE+ +G+ P
Sbjct: 9454 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPP 9499
Score = 117 bits (282), Expect = 2e-25
Identities = 120/420 (28%), Positives = 182/420 (43%), Gaps = 38/420 (9%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
KP K A P PPG+P+ I + N++TL+W T+DGG+ + GY VE L
Sbjct: 15928 KPSKVSECYVARDPCDPPGRPEAIIVTR----NSVTLQWKKPTYDGGSKITGYIVEKKEL 15983
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG-HSNYSELSDVLT----VSS 177
W++ + ++ +TGL H+Y+FRV A N G S SE + +T V
Sbjct: 15984 PEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDP 16043
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
R S +P K V A E+ KV+ + G P PTI W K D E+ ++ R I + +
Sbjct: 16044 PRISMDPK--YKDTIVVHAGESFKVDADI--YGKPIPTIQWIKGDQELSNTARLEIKSTD 16099
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+ L + D G A N G + + L P E ++ I+
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV-----LDRPGPPEGPVV--ISGV 16152
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEY- 351
K T+ KP P + D I + R + + L K + EY
Sbjct: 16153 TAEKCTLAWKP-PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYT 16211
Query: 352 -QIQAKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKV 405
+I A N +GE + V P PD P+ VT S+ + WE PA DGG ++
Sbjct: 16212 FRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEI 16271
Query: 406 GNYIVEYY-RTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
Y++E + G W K + + + + LIE +Y+FR+ AE+ G+S PS S+
Sbjct: 16272 LGYVLEKRDKEGIRWTRCHKRLIG-ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSA 16330
Score = 117 bits (281), Expect = 3e-25
Identities = 98/400 (24%), Positives = 165/400 (41%), Gaps = 21/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP +I + + ++TL W+ DGG+ + GY +E S W+R V
Sbjct: 19486 PSPPTSLEITSVTKE----SMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVY 19541
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-VT 195
+ TGL +Y++RV A N G S SE S ++ PP K ++ T
Sbjct: 19542 DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKT 19601
Query: 196 ALENDKVEFHVTFSG---IPSPTIAWFKDD-----YEIFSSRRTAITTDESTSVLLFHQI 247
+ V+ F G I T+ + K D I S R T T T+ +
Sbjct: 19602 TITIAWVK--PLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFR 19659
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ S ++ + K R E P + L+ + + + G+
Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKER---EEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGR 19716
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P + W + T R + T + L I +A R+D G+Y + +N++ + +
Sbjct: 19717 PVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V V P PP N++V +S L W+ P +DGG V NY +E W+ +
Sbjct: 19775 VKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC 19834
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + +L EG+ Y FR+ E+ +G+ P+ V+I
Sbjct: 19835 NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 19874
Score = 116 bits (280), Expect = 3e-25
Identities = 107/397 (26%), Positives = 165/397 (41%), Gaps = 17/397 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K+A P+PPGK L+D + +L W HDGG+ + GY VE G+ +W A
Sbjct: 17711 KAAEPPSPPGKVT----LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 17766
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V V+TGL +YQFRV A N+ G S+ L V ++ D Q
Sbjct: 17767 ESKVC--NAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG-VPVIAKDLTIQPSLKLPFNT 17823
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ A E+ K+E V G P P I+W KD + + R + +++VL + D
Sbjct: 17824 YSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDD 17881
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ TATN G A + + P D + + + G
Sbjct: 17882 FGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTG-GCQI 17940
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE----DTAAFL 367
+ + T +S T + +KI K +++I A+N G+ D+ A +
Sbjct: 17941 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI 18000
Query: 368 VTVT-APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V P PP VT + + W P +DGG K+ Y +E +W+K +
Sbjct: 18001 VQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKT 18060
Query: 427 --RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T L EG EY+F++ AE+ G+ PS S
Sbjct: 18061 PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 18097
Score = 115 bits (277), Expect = 8e-25
Identities = 110/423 (26%), Positives = 178/423 (42%), Gaps = 24/423 (5%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVLRPELVLTGL 145
PI+++ ++ + W HDGG P+ Y +E S W R T PI + + L
Sbjct: 10521 PIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDL 10579
Query: 146 EPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFH 205
+Y+FRV+A N++G + S S + A PPV + + D T D
Sbjct: 10580 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAI-DTTCNSVDLTWQP 10638
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVLLFHQILPSDEGE---IKCTATN 261
G S + + + ++ R A T ES + ++ +G+ + A N
Sbjct: 10639 PRHDG-GSKILGYIVEYQKVGDEEWRRANHTPESCPETKY-KVTGLRDGQTYKFRVLAVN 10696
Query: 262 RGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
G + V + L + P+L ++ +T+ L I G P P + W+
Sbjct: 10697 AAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWK 10756
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ T RI+ +TP S L+I +A D G Y + +N G T + V V P
Sbjct: 10757 KEDRDAPTKARID--VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG 10814
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLF 434
PPR++ V+ S L W+ P DDGG + NY+VE W + TS+K +
Sbjct: 10815 PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAK 10874
Query: 435 DLIEGSEYKFRIKAESPYGMS------APSSESSPVRIPGRAIDMDFLAVEARIINEALT 488
L EG++Y FR+ AE+ YG P P+ PG D+ + V+ ++
Sbjct: 10875 HLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 10934
Query: 489 RED 491
+ D
Sbjct: 10935 KPD 10937
Score = 115 bits (276), Expect = 1e-24
Identities = 102/402 (25%), Positives = 161/402 (40%), Gaps = 27/402 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P I + + ITLKW P DGG+ + GY +E R G+ W+R V
Sbjct: 21360 PPGTPDYIDVTRE----TITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSEC 21414
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI---KRLEDVT 195
+ +TGL P +Y+FR+ A N VG + S + ++ D PP+ + + +
Sbjct: 21415 QYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDE--NVPPIVEFGPEYFDGLI 21472
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P + WFKD EI IT ++ L G
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532
Query: 256 KCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
A N G A + ++ ++ P K+ P ++ + + T++ + P +
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTN--ITGEKMTLWWDAPLNDGCAPITHY 21590
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ--IQAKNIIG------EDTAAF 366
+ T I K + K + EYQ + A N G D
Sbjct: 21591 IIEKRE--TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVA 21648
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
+ T P D P + S+TL W P DGG ++ YI+E W+K I+
Sbjct: 21649 QIQYTVP-DAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 21707
Query: 427 RKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
R + T F L EG+EY+F + AE+ G+ S S ++
Sbjct: 21708 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIK 21749
Score = 113 bits (273), Expect = 2e-24
Identities = 107/411 (26%), Positives = 173/411 (42%), Gaps = 28/411 (6%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
K KN A P PPG P+ I + + N ITL+W +DGG+ + GY VE L
Sbjct: 17010 KASKNSECYVARDPCDPPGTPEPIMV----KRNEITLQWTKPVYDGGSMITGYIVEKRDL 17065
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRAS 181
W++ + V+ + ++GL +Y+FRV A N G S S+ + +T +
Sbjct: 17066 PDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 17125
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ K + + + G P PTI W + D EI S R I + ++
Sbjct: 17126 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL 17185
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ + D G+ A+N G + + L P E + ++ K
Sbjct: 17186 LIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV-----LDRPGPPEGPV--QVTGVTSEK 17238
Query: 302 TTIVGKPTPTIEWRHD-GHPII---TDDRIEISITPKFSV---LKIHSAKRSDRGEYQIQ 354
++ P P + D H ++ R+ ++ V LK+ + ++I
Sbjct: 17239 CSLTWSP-PLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 17297
Query: 355 AKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYI 409
A N +GE + V + P P PP+++ VT S+T+ W P DGG ++ YI
Sbjct: 17298 AVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 17357
Query: 410 VEYYRTGWNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPS 458
VE W+K R T++ L L E EY+FR+ AE+ G+ PS
Sbjct: 17358 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 17408
Score = 113 bits (271), Expect = 4e-24
Identities = 100/398 (25%), Positives = 169/398 (42%), Gaps = 22/398 (5%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P++ I +++LKW+ +DGGA + GY VE L W++ +
Sbjct: 19190 PPGQPEVTNITR----KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQET 19245
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+T L +Y+FRV A N S SE + + V D + +K + +
Sbjct: 19246 YFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK 19305
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ ++ + +G P P I+W KD EI RT I + ++ ++L + D G+
Sbjct: 19306 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVL 19365
Query: 258 TATNRGG-HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT---IE 313
T N G +V L+ P + +GL E + + G +E
Sbjct: 19366 TLKNVAGTRSVAVNCKVLDKPGPPAGPLEI-NGLTAEKCSLSWGRPQEDGGADIDYYIVE 19424
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
R H T E+ +T K+ + + +++ N +GE + +
Sbjct: 19425 KRETSHLAWTICEGELQMTS----CKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKAL 19480
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR- 427
P P PP ++ +T +S+TL W P DGG ++ YI+E W++
Sbjct: 19481 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19540
Query: 428 -KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V L EG EY++R+ AE+ G+S P SE+SP+
Sbjct: 19541 YDLRVKSTGLREGCEYEYRVYAENAAGLSLP-SETSPL 19577
Score = 113 bits (271), Expect = 4e-24
Identities = 101/384 (26%), Positives = 162/384 (42%), Gaps = 16/384 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I + + +A+ L W +DGGAP++ Y +E W+ R
Sbjct: 19781 PGPPTNITVQDVTKESAV-LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN-RLS 19838
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T L+ Y FRV+ N+ G +E + + ++ + E +D +L
Sbjct: 19839 YKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTW 19898
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
K E H S I + + + + A +T S L + E + A
Sbjct: 19899 LKPE-HDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLR-----ENSEYFFRVFA 19952
Query: 260 TNRGGHAVTKARLC-LEAAPKLRYP----RQYEDGLLY-EINETIFLKTTIVGKPTPTIE 313
N+ G + + L + +L P + + +Y + + I GKP P +
Sbjct: 19953 ENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVT 20012
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
DG P+ R IT + + + + +D G Y+I A N G A + V
Sbjct: 20013 LSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDR 20072
Query: 374 PDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNV 431
P PP V + ++SVTL WEPP DGG +V NYI+ T VW + + T +T +
Sbjct: 20073 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMM 20132
Query: 432 TLFDLIEGSEYKFRIKAESPYGMS 455
+ L G EY+FRIKAE+ +G+S
Sbjct: 20133 KVMKLTTGEEYQFRIKAENRFGIS 20156
Score = 112 bits (270), Expect = 6e-24
Identities = 111/415 (26%), Positives = 173/415 (41%), Gaps = 27/415 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPI---V 135
PG P P +S N++T+ W +DGG+P+ GY +E S W R PI
Sbjct: 9820 PGAPDK-PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 9878
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +TGL YQFRV A+N G S SD T + D + P F ++ D T
Sbjct: 9879 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPAT-ARDPIAPPGPPF-PKVTDWT 9936
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEG 253
D +E+ S + + Y+ D+ + L+ +
Sbjct: 9937 KSSAD-LEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFY 9994
Query: 254 EIKCTATNRGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ + +A N G VT + +P L+ D ++ I + + GK
Sbjct: 9995 KFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10054
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ W + + + IE + V+K + +RS +G Y + AKN GE +
Sbjct: 10055 PPPTVTWNMNERTLPQEATIETTAISSSMVIK--NCQRSHQGVYSLLAKNEAGERKKTII 10112
Query: 368 VTVTAPPDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AIT 425
V V P P + + ++S L W P DDGG + NY++E + W T
Sbjct: 10113 VDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYT 10172
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMS--APSSES----SPVRIPGRAIDMD 474
+ N T+ LI+G Y FRI AE+ GM +SE+ P+ +P R D++
Sbjct: 10173 VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 10227
Score = 111 bits (267), Expect = 1e-23
Identities = 96/403 (23%), Positives = 157/403 (38%), Gaps = 15/403 (3%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
V++K+ PG P I+ D N+ITL W +DGG+ + GY VE + EW
Sbjct: 17412 VYYKACDPVFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQ 17470
Query: 129 RTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF 187
P LR ++ L +Y+ RV ALN VG + + + + E +
Sbjct: 17471 IVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLD 17530
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ + + H+ F G P+P I W +++ E + + I + + L
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNC 17588
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-NETIFL--KTTI 304
+D G+ N G ++ L P ++ + E+ ++ FL + I
Sbjct: 17589 DRNDAGKYILKLENSSG-----SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPI 17643
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT- 363
+ + D +S + K+ + +++ A+N G
Sbjct: 17644 IDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 17703
Query: 364 --AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
V PP PP V++T S +L WE P DGG +V Y+VE G W
Sbjct: 17704 VETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS 17763
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
S+ N + L G EY+FR+KA + G S P PV
Sbjct: 17764 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPV 17806
Score = 111 bits (267), Expect = 1e-23
Identities = 87/391 (22%), Positives = 158/391 (40%), Gaps = 19/391 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P+++ + + + W +DGG+ + GY +E S W + ++
Sbjct: 19090 PGPPGTPKVVHATK----STMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIA 19145
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ ++GL+ Y++RV A N G S+ + + P +
Sbjct: 19146 DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVS 19205
Query: 197 LENDKVEFH--VTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH-QIL 248
L+ K + +G P W K +Y + + T E T + ++
Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYT--NIQETYFEVTELTEDQRYEFRVF 19263
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
+ + + G + K + P++ ++ D ++ + E + + I G+P
Sbjct: 19264 ARNAADSVSEPSESTGPIIVKDDV---EPPRVMMDVKFRDVIVVKAGEVLKINADIAGRP 19320
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P I W DG I R EI T ++L + R D G+Y + KN+ G + A
Sbjct: 19321 LPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC 19380
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITS 426
V P PP + + + +L W P +DGG + YIVE T W +
Sbjct: 19381 KVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL 19440
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ T+ + L++G+EY FR+ + YG+ P
Sbjct: 19441 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 19471
Score = 111 bits (266), Expect = 2e-23
Identities = 106/394 (26%), Positives = 164/394 (41%), Gaps = 32/394 (8%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++T+ W T DGGAP+ Y VE R + +T + ++GL Y FR
Sbjct: 23055 DSVTITWEIPTIDGGAPVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFR 23113
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE--DVTALENDKVEFHVTFSGIP 212
V N G E SD + VS E P+ +LE DVT + G
Sbjct: 23114 VLPENIYGIGEPCETSDAVLVS------EVPLVPAKLEVVDVTKSTVTLAWEKPLYDG-G 23166
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IKCTATNRGG----- 264
S + + + + R + T + T +L H + +EGE + A N G
Sbjct: 23167 SRLTGYVLEACKAGTERWMKVVTLKPT--VLEHTVTSLNEGEQYLFRIRAQNEKGVSEPR 23224
Query: 265 HAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
VT + L P + + + + L I G+P P W G +
Sbjct: 23225 ETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRE 23284
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+R+ + K + L I D GEY ++ KN+ G + V + P PP
Sbjct: 23285 SERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKI 23344
Query: 384 RQVD-KSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEG 439
++D S+T+ WEPP DGG + Y+VE +R GW +++T ++ L EG
Sbjct: 23345 DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVT--RSTFKFTRLTEG 23402
Query: 440 SEYKFRIKAESPYGM-SAPSSE----SSPVRIPG 468
+EY FR+ A + +G+ S SE S +RIPG
Sbjct: 23403 NEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPG 23436
Score = 110 bits (264), Expect = 3e-23
Identities = 105/398 (26%), Positives = 165/398 (41%), Gaps = 26/398 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P+ I I N +TLKW +DGG+ + GY VE L W++ + VL
Sbjct: 18108 PPGRPEAIVITR----NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 18163
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL +Y+FRV A N G+ S S+ S +T + + + K + +
Sbjct: 18164 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 18223
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G P P + W KD E+ ++ R I + + L+ + +D G+
Sbjct: 18224 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
+N GG TK+ + K+ +G L ++ K + P +
Sbjct: 18284 LKLSNVGG---TKS---IPITVKVLDRPGPPEGPL-KVTGVTAEKCYLAWNPPLQDGGAN 18336
Query: 317 DGHPIITD---DRIE-ISITPKFSVLKIHSAKRSDRGEY--QIQAKNI--IGEDTAAFLV 368
H II R+ ++ + L K EY ++ A N IGE + V
Sbjct: 18337 ISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPV 18396
Query: 369 TVT---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
T PP PP V+ S+ + W P DDGG ++ YI+E W K
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456
Query: 426 SRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ L L EG Y+FR+ AE+ G+ PS S
Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494
Score = 109 bits (263), Expect = 4e-23
Identities = 92/394 (23%), Positives = 166/394 (42%), Gaps = 15/394 (3%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P +P+ + + + N +TL W P +DGG+ + Y +E +G+ ++ + +L +
Sbjct: 10220 PERPEDLEV-KEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 10278
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ GL+ Y++RV+A+N VG S + +T + A P + + + +T
Sbjct: 10279 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAP--PTLHLDFRDKLTIRVG 10336
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
+ +SG P P ++WFKD+ ++ RT I T +T L + SD G+
Sbjct: 10337 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 10396
Query: 260 TNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
N G ++ + P P +++ + + I K + + + +
Sbjct: 10397 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDE--VTKDYMVISWKPPLDDGGSKITNYIIEK 10454
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP----- 373
+ D + ++ + K+ ++I A+N+ G ++ A
Sbjct: 10455 KEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 10514
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
PD P VT S + W P DGG + NYI+E T W + T
Sbjct: 10515 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10573
Query: 434 F---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
F DL+EG +Y+FR+ AE+ G+ PS S PV
Sbjct: 10574 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPV 10607
Score = 109 bits (261), Expect = 7e-23
Identities = 98/399 (24%), Positives = 159/399 (39%), Gaps = 26/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG+ ++ + N T+KW DGG+ + GY VE GS +W L
Sbjct: 18799 PLPPGRVTLVDVTR----NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTL 18854
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E ++GL +Y FRVAA+N+ G S+ +L V ++ D + +V A
Sbjct: 18855 --EATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDIEIKPSVELPFHTFNVKA 18911
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E K++ V F G P T+ W KD + + R +++ ++ + L + D G +
Sbjct: 18912 REQLKID--VPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE 18969
Query: 257 CTATNRGGHAVTKARLCLEAAP----KLRYPRQYEDGLLYEINETIF-----LKTTIVGK 307
+N G + + P +R D + N + + IV K
Sbjct: 18970 LCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEK 19029
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
T H + I+I S + + G K+ E +A
Sbjct: 19030 KETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYG------KSSYSESSAVVA 19083
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--IT 425
+PP PP V ++ + W+ P +DGG +V Y +EY +W KA I
Sbjct: 19084 EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKIL 19143
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L EG Y++R+ AE+ G+ S PV
Sbjct: 19144 IADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19182
Score = 108 bits (260), Expect = 9e-23
Identities = 99/399 (24%), Positives = 157/399 (39%), Gaps = 30/399 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECN-RLGSTE----WIR-TAP 132
PPG P ++ D ++ITL W +DGGAP+ GY VE ++ W R A
Sbjct: 11999 PPGPPTNFRVV-DTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12057
Query: 133 PIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 192
++R E +T L+ +Y+FRV A N VG +EL + + E + +
Sbjct: 12058 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRK 12117
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
V + G P+P + W K + R+ + ++ + L+ D
Sbjct: 12118 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV-VRKGQVDLVDTMAFLVIPNSTRDDS 12176
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ T N G + + L P D + ++ +T + P
Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV-----LDTPGPVSDLKVSDVTKT---SCHVSWAPPEND 12228
Query: 313 EWRHDGHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIGEDTAAF 366
H I+ D + ++TP+ H EY ++ A N G
Sbjct: 12229 GGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 12288
Query: 367 L---VTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--N 418
+ V + P PDPPR + VT S TL W PP DGG K+ YI Y +
Sbjct: 12289 VPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPAD 12348
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W + + ++ + L EG +YKFR+ A + G+S P
Sbjct: 12349 RWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLP 12387
Score = 108 bits (260), Expect = 9e-23
Identities = 90/402 (22%), Positives = 163/402 (40%), Gaps = 11/402 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIV 135
PAPP P++ D ++++L W +DGG+P+ GY VE R S W+R P +
Sbjct: 13092 PAPPAFPKVY----DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 13147
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +YQFRV A+N +G+S+ S++ D E + + +
Sbjct: 13148 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 13207
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ +V G P P I W K + + I + + + L + D G+
Sbjct: 13208 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 13267
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
T N G + + ++ P + + + + + I+ +P I +
Sbjct: 13268 ILTLENSCGK--KEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYV 13325
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTA 372
++ + ++ + + +++ A+N G V +
Sbjct: 13326 VQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ 13385
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
P P ++ V S ++ W+ P DGG ++ Y+V++ T N W + + S +
Sbjct: 13386 TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSLSLQYS 13444
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
DL EG EY FR+ AE+ G PS + R A D+D
Sbjct: 13445 AKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLD 13486
Score = 108 bits (260), Expect = 9e-23
Identities = 87/403 (21%), Positives = 162/403 (40%), Gaps = 12/403 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI- 134
+P PP P++I I +++ L W+ +DGG ++GY VE + EW PP
Sbjct: 16340 KPGPPNNPKVIDITR----SSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTG 16395
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
+ + + + L H+Y FR+ A+N G ++++ + V + + + ++ + +
Sbjct: 16396 INKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 16455
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ V G P+P + W K D EI + +T+ S + L+ + D G+
Sbjct: 16456 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGK 16513
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
T N G A + + P + + + + +I + ++ + +
Sbjct: 16514 YTLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNY 16571
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVT 371
+ + + KI + +++ A+N G A + V
Sbjct: 16572 IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVA 16631
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV 431
P PP ++V SV+L W P DGG K+ YIVE W + +
Sbjct: 16632 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
+ +L +G EY FR+ A + G S P S + P+ I+ D
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPD 16734
Score = 107 bits (256), Expect = 3e-22
Identities = 100/405 (24%), Positives = 168/405 (41%), Gaps = 25/405 (6%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ P+PP I+ I + ++L W HDGG+ + GY +E R GS +W T
Sbjct: 14463 KASEAPSPPDSLNIMDITK----STVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW--TH 14516
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKR 190
V E V+ L +Y F+V A+N G S E V+ + + ++
Sbjct: 14517 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQK 14576
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L A +N KVE V G P PT+ W K D + ++R T ++++L ++ + S
Sbjct: 14577 LVIAKAGDNIKVEIPVL--GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 14634
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D G TA N G + + P P ++++ + + G P
Sbjct: 14635 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 14694
Query: 310 P--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAA 365
+E R + +E++ T + K +++++A+N +G +
Sbjct: 14695 SNYVVEMRQTD----STTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITS 14750
Query: 366 FLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P PP VT S+T+ W P DGG + Y VE +W +
Sbjct: 14751 ACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILW-Q 14809
Query: 423 AITSRKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++ +F L +G Y+FR+ AE+ G S PS S P+
Sbjct: 14810 TVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 14854
Score = 107 bits (256), Expect = 3e-22
Identities = 105/399 (26%), Positives = 160/399 (40%), Gaps = 21/399 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K A P PPGK + D N+++L W HDGG+ + Y VE S +W A
Sbjct: 16629 KVAEVPQPPGKITV----DDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16684
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V + V+T L +Y FRV A+N+ G S+ L+ V V+ D EP V
Sbjct: 16685 R--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA-VPIVAKDLVI-EPDVK-PAF 16739
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ ++ V SG P PTI W KD + + R +T + L + D
Sbjct: 16740 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 16799
Query: 252 EGEIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG-KPT 309
G+ T N G + L+ + P +++D I + G + T
Sbjct: 16800 GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQIT 16859
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
I + D + D +S T + LK+ K +++I A+N G+ A
Sbjct: 16860 NYIVQKRDTTTTVWD---VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP 16916
Query: 370 VTA-----PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ A P PP T S+ + W P ++GG V Y +E +W K
Sbjct: 16917 IVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 16976
Query: 425 TS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T +L EG EY+FR+ AE+ G+ S S
Sbjct: 16977 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17015
Score = 107 bits (256), Expect = 3e-22
Identities = 103/405 (25%), Positives = 172/405 (42%), Gaps = 24/405 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K +P+PP K + I D +++L W HDGG+ + Y VE G W++ A
Sbjct: 19873 KITEKPSPPEKLGVTSISKD----SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCA 19928
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ V++GL +Y FRV A N G S+ EL +L V + P + +K
Sbjct: 19929 --VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPREL--LLPVLIKEQLEPPEIDMKNF 19984
Query: 192 EDVTAL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR--TAITTDESTSVLLFHQI 247
T ++ + SG P P + +D + ++ R T IT + T + +
Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLT--INLKES 20042
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVG 306
+ +D G + TA N G TKA + + + P + E + T+ +
Sbjct: 20043 VTADAGRYEITAANSSG--TTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYD 20100
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--EDTA 364
+ + T E+S T +++K+ + +++I+A+N G +
Sbjct: 20101 GGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID 20160
Query: 365 AFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
+ VTV P P PP VT +S+T+ W P +GG V Y +E +W
Sbjct: 20161 SACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQ 20220
Query: 422 KA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
KA + R T+ + + G Y+FR+ AE+ G+ PS S PV
Sbjct: 20221 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPV 20265
Score = 106 bits (254), Expect = 5e-22
Identities = 97/398 (24%), Positives = 163/398 (40%), Gaps = 19/398 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
APPG P P ++D ++ L+W+P DGG+ + GY VE G EW + V
Sbjct: 9923 APPGPP--FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 9980
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+LV+TGL+ Y+FRV+A+N G E++DV+ + S + + + +
Sbjct: 9981 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVH 10040
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W ++ + + I T +S ++ S +G
Sbjct: 10041 AGGVIRIIAYVSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSL 10098
Query: 258 TATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEW 314
A N G + L+ + P + T F G P IE
Sbjct: 10099 LAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK 10158
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV- 368
R T + ++T + + + + ++I A+N IG E + A ++
Sbjct: 10159 RESDRRAWTP--VTYTVTRQNAT--VQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR- 427
P+ P ++ V +VTL W PP DGG ++ NY++E G + K
Sbjct: 10215 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 10274
Query: 428 -KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ L EG Y++R+ A + G PS + P+
Sbjct: 10275 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI 10312
Score = 104 bits (249), Expect = 2e-21
Identities = 99/403 (24%), Positives = 156/403 (38%), Gaps = 20/403 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + SD + L W DGG ++GY +E + W + P
Sbjct: 9415 PGPPKDLKV-SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCG-STT 9472
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR---LEDVTA 196
V+ L +Y FRV A N G E T +PP+ +K ++
Sbjct: 9473 FVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVH 9532
Query: 197 L--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L + K + + +AW + + R D ++ E E
Sbjct: 9533 LSWKPPKNDGGSPVTHYIVECLAWDPTGTKK-EAWRQCNKRDVEELQFTVEDLVEGGEYE 9591
Query: 255 IKCTATNRGGHAVTKARL--CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ A N G + A + C P + ++ + E + + I G P PT+
Sbjct: 9592 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 9651
Query: 313 EW------RHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
W + D P++ D + + L I ++RSD G Y I A N +G +
Sbjct: 9652 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9711
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ V P PP V +TL W PP DDGG K+ NY++E W+
Sbjct: 9712 MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVS 9771
Query: 425 TS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVR 465
+ ++ T+ L+EG EY FRI A++ YG+ P SE R
Sbjct: 9772 SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETAR 9814
Score = 102 bits (245), Expect = 6e-21
Identities = 95/398 (23%), Positives = 159/398 (39%), Gaps = 24/398 (6%)
Query: 77 PAPPGKPQIIPI-LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
P PPG PI D + TL W DGGA + Y VE W +
Sbjct: 21952 PGPPG-----PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW-QVISEKC 22005
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
R + L Y FRV+A+N+ G E+ + + + A PP +RL+ V
Sbjct: 22006 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA---PP---RRLDVVD 22059
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
++ V + I + + S +++ E E
Sbjct: 22060 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEF 22119
Query: 256 KCTATNRGGHAVTKARLC--LEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKP 308
+ A N G++ + + P++ P G+ ++ + I G+P
Sbjct: 22120 RVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGITNQLITCKAGSPFTIDVPISGRP 22178
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W+ + + DR+ I+ T + L + + R D G Y + +N G T + V
Sbjct: 22179 APKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTV 22238
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P P + V+ +S L W P D GG ++ NYIVE +G W +S
Sbjct: 22239 VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV 22298
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++T + + L + EY FR+ +E+ +G+S P ES+P+
Sbjct: 22299 KRTQIKVTHLTKYMEYSFRVSSENRFGVSKP-LESAPI 22335
Score = 101 bits (241), Expect = 2e-20
Identities = 118/429 (27%), Positives = 176/429 (41%), Gaps = 42/429 (9%)
Query: 65 PRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGS 124
P + + +A P P P I + N + L W P +DGG+P+ Y VEC
Sbjct: 9499 PVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 9558
Query: 125 T-----EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
T W + V + + L +Y+FRV A+N G S S + V R
Sbjct: 9559 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS--ATVGPCDCQR 9616
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYE--IFSSRRT 231
P + +K +V E V G+P PT+ WFK D+ E ++ +
Sbjct: 9617 PDMPPSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 9674
Query: 232 AITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGL 290
+ D+ T L+ Q SD G TA N G A + RL + P P ++E
Sbjct: 9675 KLVVDD-TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 9733
Query: 291 LYEINETIFLKTTIVG-KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
++ + F G K T + + + + + +S PK I
Sbjct: 9734 ADQMTLSWFPPKDDGGSKITNYVIEKREAN---RKTWVHVSSEPKECTYTIPKLLEGHEY 9790
Query: 350 EYQIQAKNI--IGE------DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDG 401
++I A+N IGE +TA L +V PD P SVTR S+T++WE P DG
Sbjct: 9791 VFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTR---NSMTVNWEEPEYDG 9847
Query: 402 GCKVGNYIVEYYRTGWNVW-------LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGM 454
G V Y +E T W +KA+T + + LIEGS+Y+FR+ A + G+
Sbjct: 9848 GSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT-LGVSYKVTGLIEGSDYQFRVYAINAAGV 9906
Query: 455 SAPSSESSP 463
S S P
Sbjct: 9907 GPASLPSDP 9915
Score = 101 bits (241), Expect = 2e-20
Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 18/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR--TAPPI 134
P P K +++ + + +TL W +DGG+ L GY +E + G+ W++ T P
Sbjct: 23138 PLVPAKLEVVDVTK----STVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPT 23193
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
VL E +T L +Y FR+ A N+ G S E +TV R + + +
Sbjct: 23194 VL--EHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI 23251
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
VE + +G P P +WF ++ S R + T + L + D GE
Sbjct: 23252 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23311
Query: 255 IKCTATN-RGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
N G + T + L+ P + ++ + + TI + + P
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDE--IDATSITISWEPPELDGGAPLSG 23369
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
+ + + +S + S K + +++ A N IG + ++
Sbjct: 23370 YVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 23429
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITS 426
+ P PP + + +TL W PP DDGG +V YIVE + W++ +
Sbjct: 23430 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 23489
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T L EG EY+ R+ A + G PS S P+
Sbjct: 23490 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPI 23527
Score = 97.5 bits (232), Expect = 2e-19
Identities = 102/414 (24%), Positives = 162/414 (39%), Gaps = 38/414 (9%)
Query: 64 KPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
KP + A RP P P I P L D L W DGG+P+ GY VEC + G
Sbjct: 11290 KPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPG 11349
Query: 124 STEWIRTAPPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ 182
+ +W R ++R + GL ++Y+FR+ A N VG EL++ +
Sbjct: 11350 TAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPP 11409
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E + + + +T + G P P I W K+ + +R + D L
Sbjct: 11410 EVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 11469
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +D G+ +A N GHA A + + P P Q LK
Sbjct: 11470 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPG---PCQN-------------LKV 11513
Query: 303 TIVGKPTPTIEWRH---DGHPIITDDRIEI--------SITPKFSVLKIHSAKRSDRGEY 351
T V K TI W + +G IT+ +E SI ++ A EY
Sbjct: 11514 TNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEY 11573
Query: 352 --QIQAKNIIG------EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++ A+N +G T + P P N+ + + V L W P DGG
Sbjct: 11574 YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGS 11633
Query: 404 KVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
+Y VE G + W + + ++T+ + +E Y+FR++ ++ G S
Sbjct: 11634 PNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGES 11687
Score = 96.3 bits (229), Expect = 5e-19
Identities = 100/405 (24%), Positives = 162/405 (40%), Gaps = 25/405 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P + SD +A+TL W DGG+P+ GY VE + +W+R V
Sbjct: 7385 PPGPPTRLEP-SDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 7443
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP--VFIKRLEDVTA 196
+ GL KY+FRV A N G S+ ++ + + PP +K + +
Sbjct: 7444 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSV 7503
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
N H + I S I K + + + T + L ++ E +
Sbjct: 7504 RLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH----LLPGLMEGQEYSFR 7559
Query: 257 CTATNRGGHAVTKAR----LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP--TP 310
A N+ G + LC E PR E ++ T LK T+ K +P
Sbjct: 7560 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE--VINITKNTADLKWTVPEKDGGSP 7617
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-------EDT 363
+ + + + T K + + +++ A+N IG ED+
Sbjct: 7618 ITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDS 7677
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
T T P PP ++V + V L WEPP +DGG + Y++E W+KA
Sbjct: 7678 VLAKDTFTTP-GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA 7736
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
N + D+IEG+E +F+++AE+ G+ PS + + I
Sbjct: 7737 GKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSI 7781
Score = 95.9 bits (228), Expect = 7e-19
Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 12/251 (4%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W +++ + + + ++ L I P D+GE + A ++ +A+L L
Sbjct: 6445 VQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEA----RAKLELA 6500
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAPK++ Q L+ ++ + + + P EW + P+ T I T +
Sbjct: 6501 AAPKIKTADQ---DLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQ 6554
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ +I AK+ D+G Y+I +N G+ + V P P RN+ VT D V+L WE
Sbjct: 6555 TSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWE 6614
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKAI-TSRKTNVTLFDLIEGS-EYKFRIKAESPYG 453
P DGG K+ Y+VE W+ A + T+ L +G EY FR+ A + G
Sbjct: 6615 EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVG 6674
Query: 454 MSAPSSESSPV 464
P +PV
Sbjct: 6675 TGEPVETDNPV 6685
Score = 95.5 bits (227), Expect = 9e-19
Identities = 99/394 (25%), Positives = 161/394 (40%), Gaps = 32/394 (8%)
Query: 99 LKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAAL 158
L W+ DGG+ + G+ +E W + P R + +TGL +Y+FRV A
Sbjct: 8718 LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 159 NDVGHSNYSELSDVLTVS--SDRASQEPPVFIKRLEDVTALE--NDKVEFHVTFSGIPSP 214
N G E+ +L V S E + +R + L+ + G
Sbjct: 8776 NKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE 8835
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
K D+E + +R TT L HQ+ E + A N G + L +
Sbjct: 8836 KRRHDKPDFERVN-KRLCPTTSFLVENLDEHQMY-----EFRVKAVNEIGESEPSLPLNV 8889
Query: 275 -----EAAPKLRYPRQYE-DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII--TD-- 324
E P ++ D + + E + + + G P P IEW + I TD
Sbjct: 8890 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 8949
Query: 325 --DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ E+S + + L I A R D+G Y + A N +G V V P PPRN++V
Sbjct: 8950 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAV 9009
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWN--VWLKAI-TSRKTNVTLFDLIEG 439
T +S L W+ P D+GG ++ +Y+++ W + T+ + ++ LI
Sbjct: 9010 TDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPN 9069
Query: 440 SEYKFRIKAESPYGMSAPSSE-----SSPVRIPG 468
+Y+FR++A + YG+S P R+PG
Sbjct: 9070 GQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPG 9103
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 7/182 (3%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
I + L+ GKP P+I W DG P+ + + S T L I +AK+ G+Y +
Sbjct: 21080 IGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV 21139
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N + V PP P+ + SV L W+ P D+GG ++ Y +E
Sbjct: 21140 ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEK 21199
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV-----RI 466
T W +S +T + +L++ +EY+FR++AE+ YG+S P S V RI
Sbjct: 21200 RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRI 21259
Query: 467 PG 468
PG
Sbjct: 21260 PG 21261
Score = 90.6 bits (215), Expect = 3e-17
Identities = 107/409 (26%), Positives = 169/409 (41%), Gaps = 50/409 (12%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLT--GLEP 147
SD ++ L W P DGG P+ Y +E G +I P + +L T L P
Sbjct: 7992 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYI---PVMSGENKLSWTVKDLIP 8048
Query: 148 PHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVT 207
+Y FRV A+N VG Y EL + + + +PPV ++ + + TA E + +
Sbjct: 8049 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE-VHNPTA-EAMTITWKPP 8106
Query: 208 FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG---EIKCTATNRGG 264
S + + + +I +E +L + +EG + + A N G
Sbjct: 8107 LYDGGSKIMGYIIE--KIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 8164
Query: 265 HAV-TKARLCLEAAPKLRYPRQY-EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH--- 319
+ ++A +A + P+ L + + I L +I G P PTI W D +
Sbjct: 8165 ISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224
Query: 320 ---------PIITDDRIEIS--------ITPKFSV---------LKIHSAKRSDRGEYQI 353
P++ + E+ +T + S+ L++ + R D G Y I
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY 413
+ +N G A V+V P PP N SV WEPP DDGG ++ NY +E
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 8344
Query: 414 -----RTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ W V + K +VT LIEG EY FR++AE+ +G P
Sbjct: 8345 DKTKPDSEWIVVTSTLRHCKYSVT--KLIEGKEYLFRVRAENRFGPGPP 8391
Score = 89.4 bits (212), Expect = 6e-17
Identities = 62/218 (28%), Positives = 99/218 (45%), Gaps = 16/218 (7%)
Query: 74 AGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAP 132
AG P PPG P P + D ++I+L W P DGG+P++GY VE G+T+W R
Sbjct: 9201 AGDPIFPPGPPSC-PEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNE 9259
Query: 133 P--IVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK- 189
P ++ E V+ L+ KY+FRV A+N+ G S S+ + + + +EP VFI
Sbjct: 9260 PDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATD--IQEEPEVFIDI 9317
Query: 190 -RLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTDESTS 240
+ + ++ G P+P +W D D + T E++S
Sbjct: 9318 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 9377
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
V++ + S G+ TA N+ G R+ + P
Sbjct: 9378 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVP 9415
Score = 89.4 bits (212), Expect = 6e-17
Identities = 81/313 (25%), Positives = 140/313 (44%), Gaps = 24/313 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P P + D ++++L W+ DGG+ + GY +E + +W+R +
Sbjct: 23831 PPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTT 23890
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRL-EDVT 195
+TGL P +YQFR+ A NDVG S S S+ + D+ SQ + I + +D
Sbjct: 23891 MYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSV 23950
Query: 196 ALENDKVE---------FHVTFSGIPSPTIAWFKDDYEIFSSRRTAI-TTDESTSVLLFH 245
L+ +K E + V + S AW K + E ++ I E+T +
Sbjct: 23951 TLQWEKPECDGGKEILGYWVEYR--QSGDSAWKKSNKERIKDKQFTIGGLLEATE----Y 24004
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ E E + R ++ K +L AP +R ++ +D + ++ E L IV
Sbjct: 24005 EFRVFAENETGLSRPRRTAMSI-KTKLTSGEAPGIR--KEMKD-VTTKLGEAAQLSCQIV 24060
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-DTA 364
G+P P I+W G +I + ++S + L + + ++ D G Y A N +GE +T+
Sbjct: 24061 GRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETS 24120
Query: 365 AFLVTVTAPPDPP 377
+ L+ P P
Sbjct: 24121 SKLLLQATPQFHP 24133
Score = 87.8 bits (208), Expect = 2e-16
Identities = 92/410 (22%), Positives = 167/410 (40%), Gaps = 33/410 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+ + ++ + ITL W +GG+P++GY +E R ++ R +
Sbjct: 8797 PPTSPERLTY-TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 8855
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL----EDV 194
++ L+ Y+FRV A+N++G S S +V+ + D + PP RL + +
Sbjct: 8856 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVV-IQDD---EVPPTIKLRLSVRGDTI 8911
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEI------FSSRRTAITTDESTSVLLFHQIL 248
+ V +G+P P I W K++ I + ++ E+ + L + +
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
D+G TA+NR G +E + PR + + + +
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVH--VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 9029
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA-KRSDRGEYQIQAKNI----IGEDT 363
+ + D + + E +V K + K G+Y+ + + + I ++
Sbjct: 9030 SEITHYVIDKRD-ASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 9088
Query: 364 AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ V + P P PP V + S+ + W PP D+GG + Y +E G W
Sbjct: 9089 KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYW 9148
Query: 421 LKAITSRKTNVTL----FD---LIEGSEYKFRIKAESPYGMSAPSSESSP 463
+ + T V L F+ L+EG +Y+FR A + G+ PS S P
Sbjct: 9149 SRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 9198
Score = 86.6 bits (205), Expect = 4e-16
Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 298 IFLKTTIVGKPTPTIEWRHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
I L + G+P P + WR G ++ ++++ T F V I ++ R D G+Y +
Sbjct: 12127 IRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLV--IPNSTRDDSGKYSLTLV 12184
Query: 357 NIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG 416
N GE V V P P ++ V+ S + W PP +DGG +V +YIVE
Sbjct: 12185 NPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 12244
Query: 417 WNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
W +KT+ + +L+ G+EY FR+ A + YG P+ PV
Sbjct: 12245 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV 12293
Score = 86.6 bits (205), Expect = 4e-16
Identities = 92/404 (22%), Positives = 164/404 (40%), Gaps = 35/404 (8%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE---CNRLGSTEWIRTAPPIVL 136
PG+P++ +D + ++L W+ +DGG+ + GY +E + +G W++ IV
Sbjct: 22445 PGRPEV----TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 22500
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+T L Y+FRV A N G S SE + +T + A + + + D V
Sbjct: 22501 DNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLV 22560
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI--TTDESTSVLLFHQILPSDE 252
T + G P P I W K D E+ + ++ T +T+V+ F SD
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCD--RSDS 22618
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAP----KLRYPRQYED------GLLYEINETIFLKT 302
G+ T N G + + +P KL R ++ L E
Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678
Query: 303 TIVGKPTPTIEWRH-DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + T + W +G + I + ++ + + G ++++ I+
Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPG-VPVESEPIVAR 22737
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV---EYYRTGWN 418
++ T+ +PP P V ++ + + W P DGG ++ NY+V E W
Sbjct: 22738 NS----FTIPSPPGIPEEVGTGKE---HIIIQWTKPESDGGNEISNYLVDKREKKSLRWT 22790
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
K T + + L+EG +Y+FR+ A + G S PS S+
Sbjct: 22791 RVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN 22834
Score = 76.6 bits (180), Expect = 5e-13
Identities = 94/401 (23%), Positives = 158/401 (39%), Gaps = 33/401 (8%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+ D ++ L W DGG+ + Y VE G W I E+ ++ L+
Sbjct: 20974 MKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQ 21031
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
+FRV A N+ G S+ + + TV + E + VT V + +
Sbjct: 21032 SVLEFRVFAKNEKGLSDPVTIGPI-TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPY 21090
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN---RGGH 265
G P P+I+W KD + S + E+ L G+ N R
Sbjct: 21091 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAV 21150
Query: 266 AVTKARLCLEAAPK--LRYPRQYEDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPII 322
+T L + PK +R+ D ++ + + G+ T +IE R
Sbjct: 21151 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQ--- 21204
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPP 377
T+ ++ S + + K+ + + +++++A+N G + A P PP
Sbjct: 21205 TNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP 21263
Query: 378 RNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTL 433
+ ++L W+ P DGG +V + VE +W K TS R+ T
Sbjct: 21264 GKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRAT- 21322
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPSSES------SPVRIPG 468
L+EG +Y+FR+ AE+ G+S+PS S SPV PG
Sbjct: 21323 -GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG 21362
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 73.3 bits (172), Expect = 4e-12
Identities = 48/191 (25%), Positives = 80/191 (41%), Gaps = 10/191 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+PAPP + ++ D ++ L W HDGG+ + GY +E + GS W+
Sbjct: 22048 QPAPPRRLDVV----DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQ 22103
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-- 193
L + L +Y+FRV A ND G+S E + + + EP + + +
Sbjct: 22104 L--TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQI--EPTADLTGITNQL 22159
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T V SG P+P + W ++ + + R +ITT + + L + D G
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219
Query: 254 EIKCTATNRGG 264
T N G
Sbjct: 22220 RYFLTLENTAG 22230
Score = 72.9 bits (171), Expect = 6e-12
Identities = 59/208 (28%), Positives = 79/208 (37%), Gaps = 8/208 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS-RRTAITTDESTSVLL 243
PVF+ + LE F + G P P WF D +I + + ++ T L+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
PSD GE A NR G + L +EA P E I E + +K
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMK 1530
Query: 302 TTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
G P P I W + I+ +I I T + LKI S D Y A N
Sbjct: 1531 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1590
Query: 360 GEDTAAFLVTVT---APPDPPRNVSVTR 384
G DT V V A P+P R + + R
Sbjct: 1591 GRDTTRCKVNVEVEFAEPEPERKLIIPR 1618
Score = 70.9 bits (166), Expect = 2e-11
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP + D ++ L W HDGGA + Y +E + G+ EW+R A +
Sbjct: 7487 PWPPGKPTV----KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT 7542
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
L L GL +Y FRV A+N G S SE SD + PP +++
Sbjct: 7543 TQHL-LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594
Score = 69.7 bits (163), Expect = 5e-11
Identities = 42/123 (34%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
APP PP VT S L+W PP DGG KV YIVEY G W K R T
Sbjct: 9923 APPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTR 489
+ + L EG+ YKFR+ A + G+ P + + + R + D L ++A + + +
Sbjct: 9982 KLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPD-LQLDASVRDRIVVH 10040
Query: 490 EDG 492
G
Sbjct: 10041 AGG 10043
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/94 (31%), Positives = 47/94 (50%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + L++VT +E + V SG PSPT+ W+++DY+I SS IT + L+
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G C+A N G T L ++ +
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 989
Score = 68.9 bits (161), Expect = 9e-11
Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 4/146 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P + + + A+T+ W P +DGG+ + GY +E G W R +V
Sbjct: 8079 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP 8138
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
GLE +YQFRV A N G S S + T + D P V ++ +V
Sbjct: 8139 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP-TKAVD-PIDAPKVILRTSLEVK- 8195
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDD 222
D++ + SG P PTI W KD+
Sbjct: 8196 -RGDEIALDASISGSPYPTITWIKDE 8220
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/122 (32%), Positives = 63/122 (51%), Gaps = 8/122 (6%)
Query: 351 YQIQAKNIIGEDT---AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
+++ A+N G + +V + +P P P ++T S + W+PPA DGG K
Sbjct: 24299 FRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAK 24358
Query: 405 VGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
+ NY +E N W+ T R+T ++ +LIEG EY+FR+K E+ G S S S
Sbjct: 24359 IRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE 24418
Query: 463 PV 464
P+
Sbjct: 24419 PI 24420
Score = 66.9 bits (156), Expect = 4e-10
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 12/193 (6%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI---FSSRRTAITT 235
R + PP F L + TA + V F VT + P P + W+K +I + ++ +
Sbjct: 25187 RLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFES 25246
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-----KLR--YPRQYED 288
D+ L + + D+ E A N+ G KA+L + P LR + R +
Sbjct: 25247 DKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLAN 25306
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSD 347
E +++ + + G P PT++W DG P+ IEI + L I D
Sbjct: 25307 AECQE-GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPED 25365
Query: 348 RGEYQIQAKNIIG 360
G Y++ A N G
Sbjct: 25366 TGYYRVTATNTAG 25378
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/97 (35%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT--SRKT 429
APP P+N VT SV+L W P D+GG KV Y++E + + W K T ++
Sbjct: 23534 APPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIR 23593
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
TL L +G+EY+FR+ A + G P+ V++
Sbjct: 23594 EYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKV 23630
Score = 63.3 bits (147), Expect = 5e-09
Identities = 52/231 (22%), Positives = 97/231 (41%), Gaps = 10/231 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
W + + ++++ HK + + L+D+ +++ ++ + + + + P
Sbjct: 5109 WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK-AQVKELSSTAQLKVLEADPY 5167
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F +L D TA+E D++ S + WFKD EI S + +I D +L +
Sbjct: 5168 FTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKK 5225
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
D+GE C G TKA + +EA +L + G+ + ET + +
Sbjct: 5226 ADLKDKGEYVCDC----GTDKTKANVTVEA--RLIKVEKPLYGVEVFVGETAHFEIEL-S 5278
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+P +W+ G P+ EI K +L +H+ + GE QA N
Sbjct: 5279 EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAAN 5329
Score = 62.9 bits (146), Expect = 6e-09
Identities = 49/179 (27%), Positives = 77/179 (43%), Gaps = 6/179 (3%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W + E+ +S S L Q DEG + C + + G + K + L
Sbjct: 26571 VKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVKCQYDLT 26628
Query: 276 AAPKLR-YPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ +L P INE + I G+P+P IEW + PI + IS +
Sbjct: 26629 LSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRS 26688
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPDPPRNVSVTRQVDKSV 390
L+I +A SD G+Y I+AKN G+ +A A L+ + +P R V + D S+
Sbjct: 26689 RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 26747
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 3457 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3516
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 3517 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 3574
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCA 3660
Score = 62.5 bits (145), Expect = 8e-09
Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Query: 350 EYQIQAKNIIGEDTAAFL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
EY++ A+NI G + V P DPP VT KSV+L W P DGG K+
Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 19220
Query: 407 NYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPY-GMSAPSSESSP 463
YIVE WLK ++T + +L E Y+FR+ A + +S PS + P
Sbjct: 19221 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 19280
Query: 464 V 464
+
Sbjct: 19281 I 19281
Score = 61.3 bits (142), Expect = 2e-08
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 13/218 (5%)
Query: 164 SNYSELSDVLTVSSDRAS-----QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
S+ S +V TV A ++ P+ L D + E D V H+T S + + W
Sbjct: 4217 SSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIV--HLTTSITNAKEVNW 4274
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEIKCTATNRGGHAVTKARLCL--E 275
+ ++ + S + D++T L+ ++ D +GE C A N G T A+L +
Sbjct: 4275 YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 4334
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAP ++ R+ E L + I P +W G I D+ I +
Sbjct: 4335 AAPVIK--RKIEP-LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 4391
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
S L+I + D GEY +A N G + +TVT P
Sbjct: 4392 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 59.7 bits (138), Expect = 6e-08
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
PP PP V + S++L W+PPA DGG + YIVE G W + K T
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266
Query: 433 ----LFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +L E +Y+FR+KA + G S PS + +
Sbjct: 9267 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 9302
Score = 59.3 bits (137), Expect = 7e-08
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 10/216 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F +L+D T +E D+V S +P + WFKD EI S+ I D +L+
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLIL 5579
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ L SD G+ C G T +L +E +++ R + E ET +T I
Sbjct: 5580 KKALKSDIGQYTCDC----GTDKTSGKLDIEDR-EIKLVRPLHSVEVME-TETARFETEI 5633
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
+ W+ G ++ EI K L +H+ + G QA N+
Sbjct: 5634 -SEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHL 5692
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
V P ++V+VT ++ T D E +D
Sbjct: 5693 RVKPRVIGLLRPLKDVTVT--AGETATFDCELSYED 5726
Score = 59.3 bits (137), Expect = 7e-08
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 350 EYQIQAKNIIG-----EDTAAFLVT-VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++Q++A+N G E T + T+PP PP ++ VT K + + W+PP +GG
Sbjct: 7758 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 7817
Query: 404 KVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEG----SEYKFRIKAESPYGMSAPSS 459
+ Y VE G W++ + SR F + EG EY R++A + G+S PS
Sbjct: 7818 PIIGYHVEMCPVGTEKWMR-VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSE 7876
Query: 460 ESSPV 464
S V
Sbjct: 7877 ISENV 7881
Score = 58.8 bits (136), Expect = 1e-07
Identities = 71/327 (21%), Positives = 135/327 (41%), Gaps = 28/327 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE------PPVFIKRLEDVTALENDKVE 203
KY+ + + D G + E ++T D++ E P F++ LED T E D
Sbjct: 6288 KYK-HMLTIKDCGFPDEGEY--IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAV 6344
Query: 204 FHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG 263
F S + W+++ EI ++ D S L+ DE E C +R
Sbjct: 6345 FSCQLSR-EKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 6403
Query: 264 GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
++ARL +E P + R +D L + +FL + K ++W + ++
Sbjct: 6404 ----SRARLFVEEIP-VEIIRPPQDILEAPGADVVFLAE--LNKDKVEVQWLRNNMVVVQ 6456
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
D+ ++ K L+I K D+GEY+ AK+ ++ A L AP + +
Sbjct: 6457 GDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD---KEARAKLELAAAPKIKTADQDLV 6513
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSE 441
V K +T+ P D E+++ + K I T+ +T+ + + +G +
Sbjct: 6514 VDVGKPLTM--VVPYD----AYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDK 6567
Query: 442 YKFRIKAESPYGMSAPSSESSPVRIPG 468
+++I ++ +G + + +PG
Sbjct: 6568 GRYKIVLQNKHGKAEGFINLKVIDVPG 6594
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/116 (32%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTN 430
P PP N V SV L W P DGGC++ YIVE W + KTN
Sbjct: 16341 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 16400
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR--AIDMDFLAVEARIIN 484
+ + L+E EY FRI A + G+ + P+ + + A D+D +IIN
Sbjct: 16401 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 16456
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/201 (23%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 3310 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3369
Query: 353 IQAKNIIGEDTAAFLVTVTAP 373
A N +G+ ++ +++ AP
Sbjct: 3370 FVASNAVGQVSSTANLSLEAP 3390
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKT 429
PP PP + + S+TL W P DGG V Y+VE + W T R T
Sbjct: 20669 PPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTT 20728
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR----IPGRAIDMDFLAVEARIINE 485
+ +L G Y FR+ A + G P + PV+ + ID+D +A+ +I +
Sbjct: 20729 EYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLD-VALRTSVIAK 20787
Query: 486 A 486
A
Sbjct: 20788 A 20788
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P P++ + ++ +T+ W P +DGG + GY +E ST W+ +
Sbjct: 11898 KPGRPDPPEVTKVSKEE----MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAI 11953
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVG 162
+ + L P H+YQFRV A N++G
Sbjct: 11954 PERRMKVQNLLPDHEYQFRVKAENEIG 11980
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW-NVWLKAITSRKT 429
PDPP VT+ + +T+ W PP DGG + Y +E + T W V AI R+
Sbjct: 11902 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 11958
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V +L+ EY+FR+KAE+ G+ PS S PV
Sbjct: 11959 KVQ--NLLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991
Score = 56.0 bits (129), Expect = 7e-07
Identities = 38/110 (34%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P I + + +IT+ W P DGGAPL GY VE W+ + V
Sbjct: 23334 KPGPPTGPIKI---DEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSES-V 23389
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
R T L ++Y FRVAA N G +Y + S+V+ S PP
Sbjct: 23390 TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQ-SEVIECRSSIRIPGPP 23438
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/196 (26%), Positives = 81/196 (41%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF + EI S + + +
Sbjct: 2740 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVS 2798
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 2799 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 2850
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 2851 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 2907
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 2908 --VCGNDQVSATLTVT 2921
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA-ITTDEST 239
S E P +R++ T + F V G P P W+K+ +I S R +++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ + D I A N G + A L ++A + + ++ +D + E +T+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE-KDTMA 2146
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+P ++W DG + D+ + K L I + SD +Y
Sbjct: 2147 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2198
Score = 55.2 bits (127), Expect = 1e-06
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ LED T E + F S + WFK+D ++ +SR I+++ T L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE 5137
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +IK A K LEA P + + D E +E I LK V
Sbjct: 5138 VTLDDISQIKAQVKELSSTAQLKV---LEADPY--FTVKLHDKTAVEKDE-ITLKCE-VS 5190
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K P ++W DG I+ + I +LKI A D+GEY
Sbjct: 5191 KDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 5234
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEP----PVFIKRLEDVTALENDKVEFHVTFS 209
+V+ +++ S+ +T ++ + EP PV + L+D T + +F V +
Sbjct: 26320 KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT 26379
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P PT W KD I + ++ D+ L H+ SD G CT N G +
Sbjct: 26380 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26439
Query: 270 ARLCLEA 276
+L ++A
Sbjct: 26440 CKLTIKA 26446
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFH 245
F R+++ LE V FH SG P P IAW+KD I R + + + L
Sbjct: 1247 FDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+LP DEG A+N G+A+ +L +E A L P
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAP 1344
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTN 430
PP P V ++++ WE P DGG K+ Y VE +W+K + + N
Sbjct: 22343 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECN 22402
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG EY+FR A + G+S S S P+
Sbjct: 22403 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 22436
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 2922 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 2978
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 2979 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 3031
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 3032 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 3085
Score = 53.6 bits (123), Expect = 4e-06
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTS 240
P F+K ++D+ E++ V F + SP+ A W KD I S + D
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 4676
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + SD GE C + A+L +E P +R+ + E+ + + ++L
Sbjct: 4677 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP-VRFVKTLEEEVTVVKGQPLYL 4735
Query: 301 KTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ + WR DG ++ RI + L I+ A +D G Y + +N
Sbjct: 4736 SCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 4791
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 10/164 (6%)
Query: 338 LKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVTAPP----DPPRNVSVTRQVDKSVT 391
L++ E+++ A+N +GE + A + P PP N + S+T
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 17440
Query: 392 LDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD---LIEGSEYKFRIKA 448
L W P DGG ++ Y+VE + W VT F+ L E EYK R+ A
Sbjct: 17441 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 17500
Query: 449 ESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDG 492
+ G+ +S V+ P ++ L +++ + + R G
Sbjct: 17501 LNKVGLGEATSVPGTVK-PEDKLEAPELDLDSELRKGIVVRAGG 17543
Score = 52.8 bits (121), Expect = 6e-06
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 4/148 (2%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+L + + ++ V A N G + V S P+F + L + E
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQE 25311
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQILPSDEGEIKC 257
V F + SGIP PT+ W KD + I + L LP D G +
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQ 285
TATN G +A L +E +LRY +Q
Sbjct: 25372 TATNTAGSTSCQAHLQVE---RLRYKKQ 25396
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L++ P ++ V A N G S+ +S +LTV + Q P+F+++L++V E
Sbjct: 1469 LIIVPATPSDSGEWTVVAQNRAGRSS---ISVILTVEAVE-HQVKPMFVEKLKNVNIKEG 1524
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVLLFHQILPSDEGEIKC 257
++E V +G P+P I W K+ I + + I + + L + D
Sbjct: 1525 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1584
Query: 258 TATNRGGHAVTKARLCLE 275
TA N+ G T+ ++ +E
Sbjct: 1585 TAINKAGRDTTRCKVNVE 1602
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY--------RTGWNVWLKAI 424
PP PP N V S+TL W P DGG + Y+VE GW A
Sbjct: 11999 PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAA 12058
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ T+ L E EY+FR+ A++ G+ P+ ++
Sbjct: 12059 QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 12099
Score = 50.8 bits (116), Expect = 3e-05
Identities = 44/189 (23%), Positives = 79/189 (41%), Gaps = 12/189 (6%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+E VF K L ++ E D ++ S P + W+K D EI + R I T+ +
Sbjct: 5963 EEEAVFTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRI 6021
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ D G C + K ++ AA + P+ E + E + F+
Sbjct: 6022 LVIQNAHLEDAGNYNCRLPS--SRTDGKVKVHELAAEFISKPQNLE---ILEGEKAEFVC 6076
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + K + ++W+ D + + D+ ++ K VL + A D G Y + ++G
Sbjct: 6077 S--ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVV----MVGA 6130
Query: 362 DTAAFLVTV 370
AA +TV
Sbjct: 6131 ARAAAHLTV 6139
Score = 49.6 bits (113), Expect = 6e-05
Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 3250 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3309
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 3310 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3368
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPR 284
A+N G + A L LEA + + R
Sbjct: 3369 TFVASNAVGQVSSTANLSLEAPESILHER 3397
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P PT+ W G + T R +++ T S +I S + SD G Y + +N G+ A
Sbjct: 26089 GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAE 26148
Query: 366 FLVTV 370
F +T+
Sbjct: 26149 FTLTI 26153
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ L+DVTA E + F V S + + WFK+D + ++R ++ + T + F
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELSH-DNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 5492
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +I+ A A LE P + + +D E +E I +
Sbjct: 5493 LSIDDTSQIRVEAMGMSSEAKLTV---LEGDP--YFTGKLQDYTGVEKDEVIL--QCEIS 5545
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K ++W DG I I K +L + A +SD G+Y
Sbjct: 5546 KADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQY 5590
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 3552 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 3611
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 3612 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3663
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K RP PP P + ++ ++ L W P DGGA + Y V+ W A
Sbjct: 15053 KVLDRPGPPEGPLAVTEVTSEK---CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 15109
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVS 176
+ + +L +T L ++Y FRV A+N G E VL V+
Sbjct: 15110 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN 15153
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A +N K + GRP PP P +S D+ +TL W P DGG+ + Y
Sbjct: 9700 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ---MTLSWFPPKDDGGSKITNYV 9756
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+E W+ + + L H+Y FR+ A N G
Sbjct: 9757 IEKREANRKTWVHVSSE-PKECTYTIPKLLEGHEYVFRIMAQNKYG 9801
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/186 (22%), Positives = 70/186 (37%), Gaps = 8/186 (4%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L+D E +V F+ + WF+++ IF S + I + L
Sbjct: 6149 LKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 6207
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D+ + TN G V A + LR +D E F V +
Sbjct: 6208 DQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCK--VNRLNV 6265
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVT 369
T++W +G + D+R+ + +L I D GEY + A G+D + A L+
Sbjct: 6266 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAELLI 6321
Query: 370 VTAPPD 375
+ AP +
Sbjct: 6322 IEAPTE 6327
Score = 44.0 bits (99), Expect = 0.003
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPS 213
+ DV + E S V+ T + P ++ L D E D V+ V S + S
Sbjct: 2279 VKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LES 2337
Query: 214 PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC 273
W KD E+ S R I D+ + +LL + D G T G T R+
Sbjct: 2338 VEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALG--LSTSGRVS 2395
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+ + + +D + E + + L+ + +++W + I DDR++ +
Sbjct: 2396 VYSVDVI---TPLKDVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2451
Query: 334 KFSVLKIHSAKRSDRGEYQI 353
L I+ SD G Y++
Sbjct: 2452 TKQRLVINRTHASDEGPYKL 2471
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/176 (24%), Positives = 65/176 (36%), Gaps = 9/176 (5%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EPPV F K LED T E S + + WFK+ EI S++ I D
Sbjct: 5784 KEPPVEFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADGRVR 5842
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L+ H P D C A + T L + P + + R D + E F
Sbjct: 5843 KLVIHDCTPEDIKTYTCDAKD----FKTSCNLNV-VPPHVEFLRPLTDLQVREKEMARF- 5896
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
+ + ++W DG I + +I +L I+ D EY + +
Sbjct: 5897 -ECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVR 5951
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A+++A +N+ +P PP P +S D + + W P + GG + Y
Sbjct: 17888 TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYI 17944
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHS 164
VE +T W V R + +T L+ +YQFR+ A N G S
Sbjct: 17945 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 17991
Score = 43.6 bits (98), Expect = 0.004
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 6/146 (4%)
Query: 169 LSDVLTVSSDRASQEP--PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF 226
++D EP P FI + +E V F G P P + W K +
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1077
Query: 227 SSRRTAITTDESTS--VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ R ++ ++ T L+ D GE N+ G A L EA +L
Sbjct: 1078 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1137
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTP 310
Q E +LY+ T F++ VG+ P
Sbjct: 1138 QQE--MLYQTQVTAFVQEPKVGETAP 1161
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 175 VSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
V++D+ ++ P + E V LE + F +G P P + W+ + I S+R +
Sbjct: 1785 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1844
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
D L D GE+K TA N G K +L ++ R
Sbjct: 1845 YD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFR 1890
Score = 43.2 bits (97), Expect = 0.005
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 66 RKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST 125
+K V A P PP ++ SD +++ L W DGG+ + Y VE +
Sbjct: 24614 QKTVELDVADVPDPPRGVKV----SDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAE 24669
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
W+R R ++ L YQFRV A N G S SE S+ D+
Sbjct: 24670 RWLRVGQARETRYTVI--NLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDK 24721
Score = 43.2 bits (97), Expect = 0.005
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
LT+S + + + P FI + E V F SG PSP I WFK++ I S +
Sbjct: 26627 LTLSKELS--DAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS 26684
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+ + L SD G+ A N G A L
Sbjct: 26685 ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 26724
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
VH P PP P I IL D P +T+ W P DGG+P+ Y VE W
Sbjct: 11099 VHLTVLDVPGPPTGP--INIL-DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW- 11154
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ +L + L+ +Y FRV A N +G L TV+ + S P
Sbjct: 11155 GVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG--PPLDSTPTVAKHKFSPPSPPGK 11212
Query: 189 KRLEDVT 195
+ D+T
Sbjct: 11213 PVVTDIT 11219
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ +SD + +A +L W DGG+ + Y VE + +W+ TA V +
Sbjct: 12495 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWV-TALASVTKTS 12553
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHS 164
+ L P +Y FRV A N G S
Sbjct: 12554 CRVGKLIPGQEYIFRVRAENRFGIS 12578
Score = 42.7 bits (96), Expect = 0.007
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 53 GNHYSASHNAFKPRK-NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
GN+ + N R V+ K RP PP P +I ++ ++ TL W P DGG+
Sbjct: 16115 GNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEK---CTLAWKPPLQDGGSD 16171
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ Y VE W V +T L ++Y FR+ A+N G
Sbjct: 16172 IINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 16221
Score = 42.3 bits (95), Expect = 0.009
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P +I+ + SD T+ W P DGG ++ Y +E W T V
Sbjct: 11799 KPGPVRNLKIVDVSSD----RCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATV 11853
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS-DRASQ-EPPVFIK-RLE 192
L P +T L ++Y FRV A N +G +E V+ + D+ + +PP K E
Sbjct: 11854 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKE 11913
Query: 193 DVTALEN 199
++T + N
Sbjct: 11914 EMTVVWN 11920
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 28/192 (14%)
Query: 213 SPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
S + W+ ++ +S + IT ++ ++L I D+G +C N G + A L
Sbjct: 25100 STQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAEL 25159
Query: 273 ------------CLEAAPKLR--------YPRQYEDGL-LYE----INETIFLKTTIVGK 307
C K++ R E L LY + E + TI
Sbjct: 25160 FVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVH 25219
Query: 308 PTPTIEWRHDGHPII---TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W G I D + L I+S D EY + A+N GED+
Sbjct: 25220 PEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSC 25279
Query: 365 AFLVTVTAPPDP 376
+TVT P P
Sbjct: 25280 KAKLTVTLHPPP 25291
Score = 41.9 bits (94), Expect = 0.012
Identities = 40/160 (25%), Positives = 64/160 (40%), Gaps = 7/160 (4%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H+ ++ ALND G + S LTV A PV +++E + +F
Sbjct: 4308 HQGEYVCEALNDSGKT---ATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEI 4360
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
P+ WFK EI+ S + +I + + S L + D GE C A+N G
Sbjct: 4361 QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 4420
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
A L + + R+ E E + LK+ + +P
Sbjct: 4421 TATLTVTVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP 4460
Score = 41.9 bits (94), Expect = 0.012
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-----PPDPPRNVSVTRQVDK 388
K+SV K+ K ++++A+N G + A PPD P V
Sbjct: 8364 KYSVTKLIEGKEY---LFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSN 8420
Query: 389 SVTLDWEPPADDGGCKVGNYIV--EYYRTGWNVWLKAITSR-KTNVTLFDLIEGSEYKFR 445
S+ + W P D+G +G ++ E T W+ K++ + K NV L+EG Y FR
Sbjct: 8421 SMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD--GLLEGLTYVFR 8478
Query: 446 IKAESPYGMSAPSSESSP 463
+ AE+ G S S P
Sbjct: 8479 VCAENAAGPGKFSPPSDP 8496
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L+DV A E D + + P + W+KD E+ + + +D L
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2189
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
I SD + C + T A+L +E A + + ++ +D E+ E+ + +
Sbjct: 2190 IDTSDAEDYSCVLV-EDENVKTTAKLIVEGA-VVEFVKELQD---IEVPESYSGELECIV 2244
Query: 307 KPTPTIE--WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
P IE W H+ + ++ + I+ L + + D+GEY
Sbjct: 2245 SP-ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2290
Score = 41.5 bits (93), Expect = 0.016
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV-------GKP 308
K + T + T++ + + PK P + ++ + +T ++ G+P
Sbjct: 26323 KISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEP 26382
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
PT W DG I + ++S L+IH SD G Y KN G +++ +
Sbjct: 26383 RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKL 26442
Query: 369 TVTAPPD 375
T+ A D
Sbjct: 26443 TIKAIKD 26449
Score = 41.1 bits (92), Expect = 0.021
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 2483 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 2541
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 2542 KLTVLNMMKDDEGKY----TFYAGENITSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 2593
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 2594 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 2650
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 2651 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2710
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 2711 VKG-TIYSLRIKNCAIVDESVYGFRL 2735
Score = 40.7 bits (91), Expect = 0.027
Identities = 21/84 (25%), Positives = 33/84 (39%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T E + F G P PT+ W + + +S R +TT + S + SDEG
Sbjct: 26073 MTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 26132
Query: 254 EIKCTATNRGGHAVTKARLCLEAA 277
N G + L ++ A
Sbjct: 26133 NYSVVVENSEGKQEAEFTLTIQKA 26156
Score = 40.3 bits (90), Expect = 0.036
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
GRP P P + +S + + L W GG + Y VE G+T W +
Sbjct: 22242 GRPGPVTGPIEVSSVSAE---SCVLSWGEPKDGGGTEITNYIVEKRESGTTAW-QLVNSS 22297
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
V R ++ +T L +Y FRV++ N G S E + ++
Sbjct: 22298 VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPII 22336
Score = 39.9 bits (89), Expect = 0.048
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K RP PP P + ++ ++ L W P DGGA + Y +E W + +
Sbjct: 18300 KVLDRPGPPEGPLKVTGVTAEK---CYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVS 18356
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
V +T L P ++Y FRV A+N G
Sbjct: 18357 TE-VQALNYKVTKLLPGNEYIFRVMAVNKYG 18386
Score = 39.9 bits (89), Expect = 0.048
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 79 PPGKPQIIPILSDD-EPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
PP KP+ PI D+ + +++ L W +GG + Y +E T W + V R
Sbjct: 21159 PPSKPKG-PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-KMVCSSVAR 21216
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHS 164
+ L +YQFRV A N G S
Sbjct: 21217 TTFKVPNLVKDAEYQFRVRAENRYGVS 21243
Score = 39.1 bits (87), Expect = 0.084
Identities = 42/236 (17%), Positives = 86/236 (36%), Gaps = 9/236 (3%)
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+W P+ P+ + H L G ++ + ++ + ++ + + P
Sbjct: 5285 QWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSF-QAANAKSAANLKVKELPL 5343
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
+FI L DV E D+ +F S P T W K EI R + D + ++
Sbjct: 5344 IFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIK 5402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
DE + A ++ H T +L +E +L++ +D E +F T +
Sbjct: 5403 SAAFEDEAKYMFEAEDK--H--TSGKLIIEGI-RLKFLTPLKDVTAKEKESAVF--TVEL 5455
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
++W + + T + + K + D + +++A + E
Sbjct: 5456 SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE 5511
Score = 39.1 bits (87), Expect = 0.084
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +D + L W P DGG+ + Y VE S W + + V
Sbjct: 7287 PGPPAAFDI-TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTN 7344
Query: 140 LVLTGLEPPHKYQFRVAALNDVG 162
T L P +Y FRVAA N G
Sbjct: 7345 FKATKLIPNKEYIFRVAAENMYG 7367
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/170 (21%), Positives = 65/170 (38%), Gaps = 8/170 (4%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
++ L+DVT + F S P + W+ ++ S + ++ L +
Sbjct: 5702 LRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDV 5760
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
D GE++ TA + HA + P + + + ED + E T L+ V +
Sbjct: 5761 KLEDAGEVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEE-GATAVLECE-VSR 5813
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++W +G I+ + EI + L IH D Y AK+
Sbjct: 5814 ENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 5863
Score = 38.3 bits (85), Expect = 0.15
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 2/114 (1%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT--IAWFKDDYEIFSSRRTAITT 235
D+ Q+ P F K+L + F + I PT + W D + ++ R +
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN 1709
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ L + D G I C ATN+ G T A L ++ L Q +G
Sbjct: 1710 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEG 1763
Score = 37.9 bits (84), Expect = 0.19
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH-KYQFRV 155
++L W DGG+ + GY VE + W+ A E +TGL+ +Y FRV
Sbjct: 6609 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRV 6667
Query: 156 AALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
+A N VG E + + S PP+
Sbjct: 6668 SARNRVGTGEPVETDNPVEARSKYDVPGPPL 6698
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ T +G PT +EW HDG P+ +R+ + + L A D G +A N G
Sbjct: 1679 RLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1738
Query: 361 ED-TAAFLV 368
D T+A L+
Sbjct: 1739 TDHTSATLI 1747
Score = 36.3 bits (80), Expect = 0.59
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK--IHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P+ T R ++S + K I D GEY I +N GE +
Sbjct: 1061 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1120
Query: 364 AA 365
A+
Sbjct: 1121 AS 1122
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E++ L+ I G P+PT+ W + + I + +I+ + L I A D G + A
Sbjct: 912 ESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 971
Query: 356 KNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQ 385
N G T+ +L + +VT +
Sbjct: 972 VNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1002
Score = 35.5 bits (78), Expect = 1.0
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 8/131 (6%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+AS+ +NVH + RP+PP + +D + + L W +GG+ + Y
Sbjct: 8981 TASNRLGSVFRNVHVEVYDRPSPPRNLAV----TDIKAESCYLTWDAPLDNGGSEITHYV 9036
Query: 117 VECNRLG--STEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
++ EW V + + L P +Y+FRV A+N G S+ + SD +
Sbjct: 9037 IDKRDASRKKAEWEEVTNTAVEK-RYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVV 9094
Query: 175 VSSDRASQEPP 185
+ PP
Sbjct: 9095 IQDPYRLPGPP 9105
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G+PTP + W G I + + R I T + L I ++ D G Y + N G D+
Sbjct: 26857 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDS 26916
Query: 364 A 364
A
Sbjct: 26917 A 26917
Score = 33.9 bits (74), Expect = 3.2
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
V+ K +P PP P I L+ ++ +L W DGGA + Y VE W
Sbjct: 19378 VNCKVLDKPGPPAGPLEINGLTAEK---CSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 19434
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ + +T L ++Y FRV +N G
Sbjct: 19435 ICEGELQM-TSCKVTKLLKGNEYIFRVTGVNKYG 19467
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 3476 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 3535
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 3536 GKTICSAYLKINSKGEGHKDTETESAVAKSL 3566
Score = 33.1 bits (72), Expect = 5.5
Identities = 18/68 (26%), Positives = 29/68 (42%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ KPT ++W H+G + +I + T L+I D G Y+ N GE +
Sbjct: 25900 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEAS 25959
Query: 364 AAFLVTVT 371
+ VT
Sbjct: 25960 DYATLDVT 25967
Score = 32.7 bits (71), Expect = 7.3
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE--CNRLGSTEWIRTAPPIVLR 137
PG P I + D ++ KW P DGG+ + Y +E +EWI +
Sbjct: 8305 PGPP-INFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI-VVTSTLRH 8362
Query: 138 PELVLTGLEPPHKYQFRVAALNDVG 162
+ +T L +Y FRV A N G
Sbjct: 8363 CKYSVTKLIEGKEYLFRVRAENRFG 8387
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 154 bits (373), Expect = 2e-36
Identities = 112/400 (28%), Positives = 186/400 (46%), Gaps = 23/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PPGKP +++D NA T+ W DGG+P+ GY +E R + +W+R +
Sbjct: 18631 PSPPGKP----VVTDITENAATVSWTLPKSDGGSPITGYYME-RREVTGKWVRVNKTPIA 18685
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ +TGL + Y+FRV A N G S S SD + PP+ K L+D +
Sbjct: 18686 DLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPK-LKDKSR 18744
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGE 254
D V G SP + + + + +++ I DE F ++ +E
Sbjct: 18745 ETADLVWTKPLSDG-GSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYR 18803
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE------DGLLYEINETIFLKTTIVGKP 308
+ A N G + A + +P + E D + + +TI + + G+P
Sbjct: 18804 FRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRVGQTIRILARVKGRP 18863
Query: 309 TPTIEWRHDGHPIITDDRIE-ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P I W +G ++ + R++ I P+ L+I A R+D G+Y I AKN G + +
Sbjct: 18864 EPDITWTKEGKVLVREKRVDLIQDLPRVE-LQIKEAVRADHGKYIISAKNSSGHAQGSAI 18922
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR---TGWNVWLKAI 424
V V P P +N+ VT ++ T+ WE P D+GG ++ N+IVEY + GW++ +
Sbjct: 18923 VNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDV 18982
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T R +L+ +EY FR+ AE+ G+ +P+
Sbjct: 18983 TKRLIKA---NLLANNEYYFRVCAENKVGVGPTIETKTPI 19019
Score = 149 bits (361), Expect = 5e-35
Identities = 116/411 (28%), Positives = 172/411 (41%), Gaps = 21/411 (5%)
Query: 58 ASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQV 117
A + A + +K + P P G P + L+++ + L W DGG+P+ Y +
Sbjct: 17524 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNE---SCKLTWFSPEDDGGSPITNYVI 17580
Query: 118 ECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS 177
E W + R + GL Y FR+AA N +G + E S+ L +
Sbjct: 17581 EKRESDRRAWTPVTYTVT-RQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI-- 17637
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIP----SPTIAWFKDDYEIFSSRRTAI 233
+EP +R ED+ E K +T++ S I + + I + + +
Sbjct: 17638 ----REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKV 17693
Query: 234 TTDESTS-VLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQYED 288
T D S + D E + +A N G TK C + + D
Sbjct: 17694 TNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD 17753
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L + E L GKP P + W D ++ DDR I TP L+ AKRSD
Sbjct: 17754 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 17813
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGN 407
G+Y + +N G V V P PP VS + + W+PP DDGG K+ N
Sbjct: 17814 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITN 17873
Query: 408 YIVEYYRTGWNVWLKAIT-SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
YI+E G +VW+ + S KT + L+EG +Y FRI AE+ YG+S P
Sbjct: 17874 YIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 17924
Score = 147 bits (357), Expect = 2e-34
Identities = 111/397 (27%), Positives = 173/397 (43%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG PQ+ + D ++T+ W DGG+P+ GY VE W + +V
Sbjct: 22186 PGPPGTPQVTAVTKD----SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVP 22241
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+GL Y+FRV A N G S S+ S+ + PV +
Sbjct: 22242 GNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVT 22301
Query: 197 LENDKVE----FHVTFSGIPS---PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
L+ K E F +T + P W K ++ ++ + F I
Sbjct: 22302 LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAK 22361
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I + + A+T R +EA PK++ +++D ++ + E L+ + G+P
Sbjct: 22362 NAAGAI--SPPSEPSDAIT-CRDDVEA-PKIKVDVKFKDTVILKAGEAFRLEADVSGRPP 22417
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PT+EW DG + ++EI I + L + R D G Y + A N G F V
Sbjct: 22418 PTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK 22477
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-R 427
V P PP ++VT + L W PP DDGG K+ +YIV+ T W + +
Sbjct: 22478 VLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQ 22537
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L++G+EY FR+ A + YG+ P ES PV
Sbjct: 22538 VTKLKVTKLLKGNEYIFRVMAVNKYGVGEP-LESEPV 22573
Score = 143 bits (347), Expect = 3e-33
Identities = 110/397 (27%), Positives = 167/397 (42%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P I D ++ ++W ++GG+P+ GY +E S W + I+
Sbjct: 24350 PGPPGTPFATAISKD----SMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIH 24405
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ LE +Y+FRV A N VG S+ S+ D P+ +KR E
Sbjct: 24406 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEIT 24465
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ +G P W K + + ++ F I
Sbjct: 24466 LQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAK 24525
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G I ++ G K + L P++ ++ D ++ ET L+ + GKP
Sbjct: 24526 NAAGAIS-KPSDSTGPITAKDEVEL---PRISMDPKFRDTIVVNAGETFRLEADVHGKPL 24581
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTIEW I R EI T ++L + A R D G+Y ++A N+ G + V
Sbjct: 24582 PTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVK 24641
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V VT + +L W PP DGG + +Y+VE T W +
Sbjct: 24642 VLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVV 24701
Query: 429 TN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
TN + + L+EG+EY FRI A + YG+ P ES+PV
Sbjct: 24702 TNSLKVTKLLEGNEYVFRIMAVNKYGVGEP-LESAPV 24737
Score = 143 bits (346), Expect = 3e-33
Identities = 111/397 (27%), Positives = 176/397 (44%), Gaps = 18/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++ + S D ++ ++W DGG+ + GY +E S W++ +
Sbjct: 23268 PGPPGTP-VVTLSSRD---SMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIP 23323
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ + TGLE +Y+FRV+A N VG S++S+ D + + + R
Sbjct: 23324 QTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVT 23383
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + +T F I
Sbjct: 23384 LQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIAR 23443
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++ P++ +Y+D ++ E+ + I GKP
Sbjct: 23444 NAAGVFSEPSESTG--AIT-ARDEVDP-PRISMDPKYKDTIVVHAGESFKVDADIYGKPI 23499
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
PTI+W + R+EI T + L + A R D G Y ++AKN+ GE + V
Sbjct: 23500 PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 23559
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRK 428
V P PP V ++ + TL W+PP DGG + NYIVE T VW + +
Sbjct: 23560 VLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQ 23619
Query: 429 T-NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L+EG+EY FRI A + YG+ P ES PV
Sbjct: 23620 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEP-LESEPV 23655
Score = 142 bits (343), Expect = 8e-33
Identities = 110/402 (27%), Positives = 166/402 (41%), Gaps = 23/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P++ I D ++ + WA DGG + GY +E W + +
Sbjct: 25829 PGPPSTPEVSAITKD----SMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 25884
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRVAA N G SE S V + D P ++ D +
Sbjct: 25885 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS-VFYRACDALYPPGPPSNPKVTDTSR 25943
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G +P + + E + T T F + E
Sbjct: 25944 SSVSLAWSKPIYDG-GAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 26002
Query: 257 ---CTATNRG--------GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
C + G G V + R+ P++ ++ + T+ L TI
Sbjct: 26003 FRICAINSEGVGEPATLPGSVVAQERI---EPPEIELDADLRKVVVLRASATLRLFVTIK 26059
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P P ++W I+TD R +I +T F++L I + R D G Y + +N G TA
Sbjct: 26060 GRPEPEVKWEK-AEGILTD-RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAF 26117
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
V V P P N+++ SVTL WEPP DGG K+ NYIVE T +
Sbjct: 26118 VNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITN 26177
Query: 426 S-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ KT + +L EG Y FR+ A + YG+ P+ + PV++
Sbjct: 26178 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 26219
Score = 140 bits (340), Expect = 2e-32
Identities = 112/412 (27%), Positives = 182/412 (44%), Gaps = 28/412 (6%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P+ P ++ + D I + W DGG+P+ GY +E S W++ +
Sbjct: 20017 GVPSEPKNARVTKVNKD----CIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTL 20072
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V E GL +Y FR+ ALN G S S+ ++ +T R +PP + + DV
Sbjct: 20073 VRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA---RMPVDPPGKPEVI-DV 20128
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTA---ITTDESTSVLLF--- 244
T + G S I +F + ++ + TA I +E T+ L
Sbjct: 20129 TKSTVSLIWARPKHDG-GSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKA 20187
Query: 245 -HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+Q + + + VT L P++ + L + + L T
Sbjct: 20188 QYQFRAIARTAVNISPPSEPSDPVTI--LAENVPPRIDLSVAMKSLLTVKAGTNVCLDAT 20245
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ GKP PT+ W+ DG + + I++++ L++ S R D G+Y I A+N G +
Sbjct: 20246 VFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKS 20305
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK- 422
A + V P PP +V + + L WEPP +DGG ++ NYIV+ T W +
Sbjct: 20306 ATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQV 20365
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGM-----SAPSSESSPVRIPGR 469
+ T T+ ++ LIEG EY+FRI AE+ YG+ + P+ +P PGR
Sbjct: 20366 SATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGR 20417
Score = 138 bits (334), Expect = 1e-31
Identities = 116/406 (28%), Positives = 174/406 (42%), Gaps = 26/406 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P I+ + D +++L W GG+P+ GY +E S W R +
Sbjct: 21103 PDAPPPPNIVDVRHD----SVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIR 21158
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +Y+FRV A+N G S S+ V+ + +P V VT
Sbjct: 21159 MRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT 21218
Query: 196 ALEND-KVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + K + +G P+ +W K ++ +T F
Sbjct: 21219 LIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAK 21278
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEA--APKLRYPRQYEDGLLYEINETIFLKT-TIVG 306
+ G I + + T+ +C + AP + +DGL + +TI L +I+G
Sbjct: 21279 NTAGAISAPSES------TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 21332
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
KP P W G I D +I+ TP S+L I A R D GEY I A N G
Sbjct: 21333 KPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHV 21392
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKA 423
VTV P PP V ++ + TL W PP +DGG + +YI+E T W V +
Sbjct: 21393 KVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED 21452
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I S + T LI+G+EY FR+ A + YG P +S PV++ R
Sbjct: 21453 IQSCRHVAT--KLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDR 21495
Score = 138 bits (333), Expect = 1e-31
Identities = 112/405 (27%), Positives = 183/405 (45%), Gaps = 28/405 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIV 135
P P P + ++D I + W P +GG+P+ GY VE +G+ +W+R + PI
Sbjct: 15208 PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIK 15267
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
V G+ P +Y RV A+N +G S SE+S+ + V+ D + P D+
Sbjct: 15268 DLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV-VAKDPDCK--PTIDLETHDII 15324
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+E +K+ V F +P PT++W KD E+ +S R + D ++ L + + +D G
Sbjct: 15325 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIY 15384
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT--PTIE 313
T N+ G A + + P + D T G P +E
Sbjct: 15385 TITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLE 15444
Query: 314 WRHDGH----PIITDDRIEISITPKFSV------LKIHSAKRSDRGEYQIQAKN-IIGED 362
R G P+++ + ++S T K + ++ + + GEY I+ KN +I +D
Sbjct: 15445 RREAGRRTYIPVMSGEN-KLSWTVKDLIPNGEYFFRVKAVNKVGGGEY-IELKNPVIAQD 15502
Query: 363 TAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
PPDPP +V V +++T+ W+PP DGG K+ YI+E G W +
Sbjct: 15503 P-------KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR 15555
Query: 423 AITSRK--TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
T L EG EY+FR++AE+ G+S PS + P +
Sbjct: 15556 CNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTK 15600
Score = 137 bits (332), Expect = 2e-31
Identities = 109/407 (26%), Positives = 169/407 (41%), Gaps = 16/407 (3%)
Query: 65 PRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K + +A P PPGKP++I + + ++L WA HDGG+ + GY VE +L
Sbjct: 20104 PSKPTEYVTARMPVDPPGKPEVIDVTK----STVSLIWARPKHDGGSKIIGYFVEACKLP 20159
Query: 124 STEWIR--TAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
+W+R TAP + + E TGLE +YQFR A V S SE SD +T+ ++
Sbjct: 20160 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 20219
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ + +T V T G P PT++W KD + + + +
Sbjct: 20220 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT 20279
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D G+ TA N G A + L+ K P + +Y + +
Sbjct: 20280 LELFSVNRKDSGDYTITAENSSGS--KSATIKLKVLDKPGPPASVKINKMYSDRAMLSWE 20337
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + + D + ++S T + + +++I A+N G
Sbjct: 20338 PPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGV 20397
Query: 362 DTAAFLVTVTA--PPDPPRNVS--VTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTG 416
F A P DPP V + K +T+ W+PPADDGG + Y++E T
Sbjct: 20398 GDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQ 20457
Query: 417 WNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K TL L EG+EY+FR+ A + G PS S
Sbjct: 20458 AVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDAS 20504
Score = 136 bits (328), Expect = 5e-31
Identities = 103/399 (25%), Positives = 179/399 (44%), Gaps = 21/399 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP P + + + +IT+ W +GG+ + GY +E S W + ++
Sbjct: 27597 PGPPSTPWVTNVTRE----SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIR 27652
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+T + Y+FRV A N G S S+ VL + + EPP + R+ D++
Sbjct: 27653 TTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDAC----EPPRNV-RITDIS 27707
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLLFHQILPSDEGE 254
F G S + + ++ R T A T+ + + + + + + E
Sbjct: 27708 KNSVSLSWQQPAFDG-GSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYE 27766
Query: 255 IKCTATNRGGHAVTKARL-----CLEA--APKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ A N G + + C+++ P + P +Y + + Y ++ L+ I GK
Sbjct: 27767 FRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGK 27826
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PTIEW D + T+ + + T + + I A R + G Y+++ +N +G +A
Sbjct: 27827 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIR 27886
Query: 368 VTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAIT 425
V + P PP + + +TL W PPADDGG K+ +YIVE T VW + +
Sbjct: 27887 VQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEH 27946
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +T +I+G+EY FR++A + YG+ P S V
Sbjct: 27947 LEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 27985
Score = 135 bits (327), Expect = 7e-31
Identities = 106/380 (27%), Positives = 170/380 (44%), Gaps = 20/380 (5%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+SD + + WAP +DGG+ + Y VE W T P V + +T L P
Sbjct: 19634 VSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-STVTPEVKKTSFHVTNLVPG 19692
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
++Y FRV A+N+ G +++ + S + +PP ++LE +N T
Sbjct: 19693 NEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPP---RKLEVTEMTKNS-----ATL 19744
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVL--LFHQILPSDEGE---IKCTATN 261
+ +P K D I S R D T SV+ L + EG+ + A N
Sbjct: 19745 AWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARN 19804
Query: 262 RGGHAVTK-ARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
G ++ + A EA +L P+ + + + + + ++ + GKP PT +W+
Sbjct: 19805 AVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGED 19864
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++T + + S+L I R D G Y + A+N G DT V V P PP+
Sbjct: 19865 EVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 19924
Query: 380 VSVTRQVD-KSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLI 437
+D + +L W P +DGG + NYIVE W+ A+ S KT+ + LI
Sbjct: 19925 PFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLI 19984
Query: 438 EGSEYKFRIKAESPYGMSAP 457
G EY FR++AE+ +G+S P
Sbjct: 19985 PGQEYIFRVRAENRFGISEP 20004
Score = 134 bits (324), Expect = 2e-30
Identities = 117/397 (29%), Positives = 170/397 (42%), Gaps = 25/397 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPGKP +P+ + + +TLKWA + GG + Y VE L + W++ +L
Sbjct: 22286 PPGKP--VPL--NITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILEN 22341
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL Y+FRV A N G S SE SD +T D + + V +K + V
Sbjct: 22342 EFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILK 22401
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W KD E+ + + I + ++ L+ D G
Sbjct: 22402 AGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTL 22461
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHD 317
TATN GG A K ++ + P +G L + E K + P
Sbjct: 22462 TATNPGGFA--KHIFNVKVLDRPGPP----EGPL-AVTEVTSEKCVLSWFPPLDDGGAKI 22514
Query: 318 GHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIG-----EDTAAF 366
H I+ T ++ + V K+ K EY ++ A N G E
Sbjct: 22515 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 22574
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V PPDPP+N VT S+ + W P DGG ++ NYIVE W+K
Sbjct: 22575 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 22634
Query: 427 RKTNV--TLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ + L EG EY+FRI AE+ G+SAPS S
Sbjct: 22635 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 22671
Score = 133 bits (322), Expect = 3e-30
Identities = 116/431 (26%), Positives = 177/431 (41%), Gaps = 21/431 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + S+ ++ L W DGG+ + Y VE + S +W + +
Sbjct: 18237 PGPPRDLEV-SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSH 18295
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++Y FRVAA N G + E + PP + + DV E
Sbjct: 18296 FA-KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEV 18353
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
V G SP + + E + T + ++ + + A
Sbjct: 18354 SLVWNKPDRDG-GSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTG-LQQGKTYRFRVKA 18411
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYED-----GLLYEINETIFLKTTIVGKPTPTIEW 314
N G + + +E KL P D GL+ + T+ I G P PT +W
Sbjct: 18412 ENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKW 18471
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
DG I TD+ + SVL I + R D GEYQI N G T A +TV P
Sbjct: 18472 TTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVP 18531
Query: 375 DPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVT 432
PP +++ + +T+ W+PP DDGG V NYIVE T + W + + S KT +
Sbjct: 18532 GPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLK 18591
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSES--------SPVRIPGRAIDMDFLAVEARIIN 484
+ L +G EY FR++AE+ G+ P + SP PG+ + D + A ++
Sbjct: 18592 IPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTD-ITENAATVS 18650
Query: 485 EALTREDGEEP 495
L + DG P
Sbjct: 18651 WTLPKSDGGSP 18661
Score = 132 bits (320), Expect = 5e-30
Identities = 113/420 (26%), Positives = 171/420 (40%), Gaps = 17/420 (4%)
Query: 54 NHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR 113
NHY +P ++ K R PPG P+ P +S+ N T+ W DGG+ +
Sbjct: 21477 NHYGKG----EPVQSEPVKMVDRFGPPGPPEK-PEVSNVTKNTATVSWKRPVDDGGSEIT 21531
Query: 114 GYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
GY VE S W+R V +TGL+ Y+FRV+A N G SE SD +
Sbjct: 21532 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSV 21591
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
+ D A P + D T + G T + + ++
Sbjct: 21592 LMK-DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT-GYVVEHQKVGDEAWIKD 21649
Query: 234 TTDESTSVLLF--HQILPSDEGEIKCTATNRGG----HAVTKARLC-LEAAPKLRYPRQY 286
TT + + F + ++ + +A N G + + E AP +
Sbjct: 21650 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAEL 21709
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS 346
L+ +I + I G+P P + W D I +R I T F++L I R
Sbjct: 21710 RRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKNRANIENTESFTLLIIPECNRY 21767
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D G++ + +N G+ + V V P P N+ T SVTL W+ P DGG ++
Sbjct: 21768 DTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRIT 21827
Query: 407 NYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
NYIVE + A T K + L EG EY FR+ AE+ YG+ P+ + PV+
Sbjct: 21828 NYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVK 21887
Score = 132 bits (320), Expect = 5e-30
Identities = 105/398 (26%), Positives = 168/398 (42%), Gaps = 19/398 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P + I D + ++W +DGG + GY +E S W++ +
Sbjct: 25432 PGPPGTPFVTSISKDQ----MLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQ 25487
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS--DRASQEPPVFIKRLEDV 194
+ TGL+ +Y+F+V+A N VG S++S+ D + + I R
Sbjct: 25488 DTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVT 25547
Query: 195 TALENDKVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + +G P W K + ++ F I
Sbjct: 25548 LKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIAR 25607
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
+ G + + G A+T AR ++A P +Y+D ++ ET L+ I GKP
Sbjct: 25608 NAAGNFSEPSDSSG--AIT-ARDEIDA-PNASLDPKYKDVIVVHAGETFVLEADIRGKPI 25663
Query: 310 PTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W DG + T R+EI T + + L + R+D G+Y ++ N+ G + V
Sbjct: 25664 PDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 25723
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P PP + VT + L W PP DGG + +YI+E T W + T
Sbjct: 25724 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV 25783
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ N + L+ G+EY FR+ A + YG+ P ES PV
Sbjct: 25784 QALNYKVTKLLPGNEYIFRVMAVNKYGIGEP-LESGPV 25820
Score = 132 bits (318), Expect = 9e-30
Identities = 105/398 (26%), Positives = 167/398 (41%), Gaps = 15/398 (3%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P++ + D ++ + W DGG+ + GY +E W R ++
Sbjct: 23664 PDAPKAPEVTTVTKD----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIG 23719
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H Y+FRV+A N G S S S PP K ++ +
Sbjct: 23720 ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRS 23779
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G K D + T + + + ++L E +
Sbjct: 23780 SVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFR 23839
Query: 257 CTATNRGG---HAVTKARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
A N+ G HA + +E AP + + + ++ L I G+PTP
Sbjct: 23840 ICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTP 23899
Query: 311 TIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
++W + DG I D I I +T F+ L + + R D G+Y + +N G +A V
Sbjct: 23900 EVKWGKVDGE--IRDAAI-IDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVR 23956
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RK 428
V P PP N+ VT SV++ WEPP DGG K+ NYIVE + +T+ K
Sbjct: 23957 VLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHK 24016
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + L EG Y FR+ AE+ YG+ P+ + P+++
Sbjct: 24017 NSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKV 24054
Score = 131 bits (317), Expect = 1e-29
Identities = 115/400 (28%), Positives = 169/400 (42%), Gaps = 25/400 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P+ + + D+ ++L W DGG+P+ GY VE G+ +WI+ V
Sbjct: 18336 PPGPPKDLHHVDVDKTE-VSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKT--VTNL 18392
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP---VFIKRLEDVT 195
E V+TGL+ Y+FRV A N VG L D + PP + +K +E +
Sbjct: 18393 ECVVTGLQQGKTYRFRVKAENIVGLG----LPDTTIPIECQEKLVPPSVELDVKLIEGLV 18448
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
V F G+P PT W D EI + + TD +SVL L D GE
Sbjct: 18449 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 18508
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIE 313
+ T +N G L + P P +L E TI + +P I
Sbjct: 18509 QITVSNAAGSKTVAVHLTVLDVPG---PPTGPINILDVTPEHMTISWQPPKDDGGSPVIN 18565
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV 368
+ + D +S + LKI ++ ++++A+N IG + T
Sbjct: 18566 YIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAK 18625
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TG-W-NVWLKAIT 425
+PP PP VT + + T+ W P DGG + Y +E TG W V I
Sbjct: 18626 HKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIA 18685
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
K VT L EG+ Y+FR+ AE+ G+S PS S P++
Sbjct: 18686 DLKFRVT--GLYEGNTYEFRVFAENLAGLSKPSPSSDPIK 18723
Score = 131 bits (317), Expect = 1e-29
Identities = 113/399 (28%), Positives = 178/399 (44%), Gaps = 24/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP KP+I+ D IT+ W DGGAP+ GY VE + T+W +T+ +
Sbjct: 27011 PSPPSKPKIV----DSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDW-KTSIQSLR 27065
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLEDVT 195
E ++GL +Y FRV ++N VG S+ S+ SD ++ +R +E P+F I T
Sbjct: 27066 GTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDP-QIAKER--EEEPLFDIDSEMRKT 27122
Query: 196 ALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ F +T F G P P + W K D ++ +R TTD TS L +D G
Sbjct: 27123 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAYVDTTDSRTS-LTIENANRNDSG 27180
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPTPTI 312
+ T N ++ A L L L P + + ++ E+ L +
Sbjct: 27181 KYTLTIQN----VLSAASLTL-VVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAP 27235
Query: 313 EWRHDGHPIITDDRIEISITPKFSVL--KIHSAKRSDRGEYQIQAKNIIGEDTAAFL--- 367
+ + +S+T + L K+ + + +++ +N G A
Sbjct: 27236 VKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEG 27295
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR 427
V +T P PP + VT SV+L W P DGG ++ +Y+VE G W+K ++
Sbjct: 27296 VKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAK 27355
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ + L E SEY FR+ AE+ G+S P PV I
Sbjct: 27356 STHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLI 27394
Score = 130 bits (314), Expect = 3e-29
Identities = 101/412 (24%), Positives = 168/412 (40%), Gaps = 15/412 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+ P++S+ + +T+ W P DGG+P+ GY +E + W + ++
Sbjct: 20414 PPGRCDP-PVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIER 20472
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L TGL+ +Y+FRV A+N G S+ S + PP F K + D T
Sbjct: 20473 TLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPAPPAFPK-VYDTTRSS 20531
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ--ILPSDEGEIK 256
+ G SP I + + S ++ F ++ + + +
Sbjct: 20532 VSLSWGKPAYDG-GSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFR 20590
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYE------DGLLYEINETIFLKTTIVGKPTP 310
A N+ G++ + P + E L+ T+ L + G+P P
Sbjct: 20591 VYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPP 20650
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W + ++I T + L+ + + D G+Y + +N G+ +V V
Sbjct: 20651 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 20710
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKT 429
P PP NV+V S + WEPP DGG + NY+V+ W T KT
Sbjct: 20711 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKT 20770
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAIDMDFLAV 478
+ + +L EG Y FR+ AE+ YG+ P V+ PG +D+ +V
Sbjct: 20771 SFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRSV 20822
Score = 130 bits (313), Expect = 3e-29
Identities = 101/387 (26%), Positives = 166/387 (42%), Gaps = 16/387 (4%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P PI+ D N++ +KW D G+P+ GY +E + ST W R ++
Sbjct: 15829 PPDAPDK-PIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNAL 15886
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+ + GL Y FRV A N G +S SD T + PP I R+ D ++
Sbjct: 15887 KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPP--IPRVTDTSSTT 15944
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF--HQILPSDEGEIK 256
+ F+G + +F D ++ + + T++ V + +I + +++
Sbjct: 15945 IELEWEPPAFNG-GGEIVGYFVDK-QLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLR 16002
Query: 257 CTATNRGGHAVTKARLCLEAA-----PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+A N G + A P + + G+ +T+ + + G+P PT
Sbjct: 16003 VSAVNAAGEGPPGETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPT 16062
Query: 312 IEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
W + +G + DR+ I S L I A R D G Y I A N G AA V V
Sbjct: 16063 KVWTKEEGE--LDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 16120
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN 430
P P ++ K L+W P DDGG ++ +I+E + W + I + ++
Sbjct: 16121 FDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSK 16180
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ L+EG EYKFR+ A++ +G P
Sbjct: 16181 CDITGLLEGQEYKFRVIAKNKFGCGPP 16207
Score = 129 bits (312), Expect = 5e-29
Identities = 105/402 (26%), Positives = 174/402 (43%), Gaps = 22/402 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P++ I N++T+ W+ DGG+ + GY +E S W + +
Sbjct: 27993 PGPPGIPEVTKITK----NSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR 28048
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+TGL YQ+RV A+N G +SE S+ + PP I R+ D T
Sbjct: 28049 DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKI-RIADSTK 28107
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT--DESTSVLLFHQILPSDEGE 254
+ G S + + + T ++T + T+ + + P
Sbjct: 28108 SSITLGWSKPVYDG-GSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYY 28166
Query: 255 IKCTATNRGGHAV-------TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ +A N G +A+ LEA P++ ++ + E + + G+
Sbjct: 28167 FRVSAVNCAGQGEPIEMNEPVQAKDILEA-PEIDLDVALRTSVIAKAGEDVQVLIPFKGR 28225
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ WR D + +D R I T S+L I R+D G+Y + +N +GE ++ +
Sbjct: 28226 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 28285
Query: 368 -VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P + + V +VTL W+PP DGG + NY++E W ++ S
Sbjct: 28286 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTW--SVVS 28343
Query: 427 RKTNVTLFDLIEGSE---YKFRIKAESPYGMSAPSSESSPVR 465
K + T F LI+ SE + FR+ AE+ G+ P + PV+
Sbjct: 28344 HKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK 28385
Score = 128 bits (310), Expect = 8e-29
Identities = 119/462 (25%), Positives = 193/462 (41%), Gaps = 36/462 (7%)
Query: 65 PRKNVHWKSA-GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
P K V K +P+PP P+ I D N++ L W P HDGG+ + GY VE ++G
Sbjct: 18027 PSKPVFAKDPIAKPSPPVNPEAI----DTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVG 18082
Query: 124 STEWIRT--APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS 181
EW R P + +TGL Y+FRV A+N G S+ + + + + V DR
Sbjct: 18083 DEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLV-KDRL- 18140
Query: 182 QEPPVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
EPP I + D + G+P P + W K+D + + R +T
Sbjct: 18141 -EPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVT--PV 18197
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
S L D G T N G ++ + P PR E + + + +
Sbjct: 18198 GSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKP--GPPRDLEVSEIRKDSCYL 18255
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE---YQIQA 355
K + + + + + + +S T K K H AK + G +++ A
Sbjct: 18256 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSK---KKSHFAKHLNEGNQYLFRVAA 18312
Query: 356 KNIIGE----DTAAFLVTVTA--PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNY 408
+N G +T + + PP PP+++ VDK+ V+L W P DGG + Y
Sbjct: 18313 ENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHV-DVDKTEVSLVWNKPDRDGGSPITGY 18371
Query: 409 IVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV---- 464
+VEY G W+K T + L +G Y+FR+KAE+ G+ P + + P+
Sbjct: 18372 LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDT-TIPIECQE 18430
Query: 465 RIPGRAIDMDFLAVEARIINEALTREDGEEPRISPAPRRKRT 506
++ ++++D +E ++ T R P P K T
Sbjct: 18431 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT 18472
Score = 128 bits (309), Expect = 1e-28
Identities = 97/377 (25%), Positives = 156/377 (41%), Gaps = 17/377 (4%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
+++TL W P DGGA + Y VE R + + T + + L+ Y FR
Sbjct: 26140 DSVTLSWEPPLIDGGAKITNYIVE-KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFR 26198
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSP 214
V A N+ G +E ++ + VS EPP+ R+ V N
Sbjct: 26199 VLASNEYGIGLPAETTEPVKVS------EPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 26252
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA------VT 268
I + + + S + + T T + +E + A N G + V
Sbjct: 26253 KITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP 26312
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+E P + P + + E + + G+P T+ WR DG + R+
Sbjct: 26313 VIARDIEIKPSVELPFHTFN---VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 26369
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
+S + + L I A + D G Y++ N G T + V P PP + +
Sbjct: 26370 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 26429
Query: 389 SVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNVTLFDLIEGSEYKFRIK 447
S+T+ W PP DGGC++ NYIVE T W + + +T++ + L GSEY+FR+
Sbjct: 26430 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVC 26489
Query: 448 AESPYGMSAPSSESSPV 464
AE+ YG S+ S S+ V
Sbjct: 26490 AENRYGKSSYSESSAVV 26506
Score = 127 bits (307), Expect = 2e-28
Identities = 73/191 (38%), Positives = 97/191 (50%), Gaps = 2/191 (1%)
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
+ AP++ + GL + I L T+ GKP P I W + D RI I PK
Sbjct: 14612 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 14671
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW 394
S + I +KRSD G Y I+A N+ G TA V V P PP +T ++S L W
Sbjct: 14672 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 14731
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PP DDGG K+ NY+VE T VW K + T + TN LI EY FR+ AE+ YG
Sbjct: 14732 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 14791
Query: 454 MSAPSSESSPV 464
+ P ++SP+
Sbjct: 14792 VGEP-VQASPI 14801
Score = 127 bits (306), Expect = 2e-28
Identities = 108/398 (27%), Positives = 168/398 (42%), Gaps = 19/398 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ RP PPGK ++ + N+++L W HDGG+ + GY VE GS +W A
Sbjct: 22971 KASERPLPPGKITLMDVTR----NSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCA 23026
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V E +TGL +Y FRV+A N+ G S+ +LS V ++ D PP F
Sbjct: 23027 TVKVT--EATITGLIQGEEYSFRVSAQNEKGISDPRQLS-VPVIAKDLVI--PPAFKLLF 23081
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
T L + ++ V F G P+P + W KD+ + + R + E+ S+L D
Sbjct: 23082 NTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRED 23141
Query: 252 EGEIKCTATNRGGHAV-TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G TN G A+ T + L+ P + ++ I T+ +
Sbjct: 23142 VGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSI--TLSWGPPKYDGGSS 23199
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ + T +S T + +K K +++I A+N G+ T
Sbjct: 23200 INNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPT 23259
Query: 371 TAP-----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
A P PP VT S+ + W P DGG +V Y +E +W+K
Sbjct: 23260 VAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNK 23319
Query: 426 S--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ +T L EG EY+FR+ AE+ G+ PS S
Sbjct: 23320 TPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 23357
Score = 127 bits (306), Expect = 2e-28
Identities = 101/393 (25%), Positives = 175/393 (44%), Gaps = 17/393 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP ++ I D ++++ W P DGG+ ++ Y VE R + +
Sbjct: 23961 PSPPVNLKVTEITKD----SVSITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCH 24015
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ + L+ Y FRV A N+ G ++ +D + V+ +PP I ++DVT
Sbjct: 24016 KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKIT-VDDVTR 24071
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
G S I + + S + + +S ++ + + +E +
Sbjct: 24072 NSVSLSWTKPEHDG-GSKIIQYIVEMQAKHSEKWSECARVKSLQAVITN-LTQGEEYLFR 24129
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL---YEINETIFLKTTIVGKPTPTIE 313
A N G + ++ A L + ++ + + ++ I G+P PTI
Sbjct: 24130 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTIT 24189
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG P+ RI ++ + + L I + D G+Y I N++G+ TA+ +
Sbjct: 24190 WTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 24249
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
PDPP+ V +S+TL W PP GGC++ NYIV+ T VW + + T +T +
Sbjct: 24250 PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTL 24309
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L G+EY+FRI AE+ YG S + ES P+
Sbjct: 24310 KVTKLKTGTEYQFRIFAENRYGQSF-ALESDPI 24341
Score = 126 bits (304), Expect = 4e-28
Identities = 108/397 (27%), Positives = 165/397 (41%), Gaps = 19/397 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP I + SD ++L W +DGG+ + G+ VE S W + +
Sbjct: 28684 PGPPGKPVIYNVTSD----GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 28739
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E TGL YQFRV A N G S+ S+ S S P +I DVT
Sbjct: 28740 GREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI----DVTR 28795
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E ++++ S + + + + TD S + P D E +
Sbjct: 28796 -ETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFR 28854
Query: 257 CTATNRGGHAVTKARLC-------LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
A N G ++ P + + +Y DGL+ + E++ +K + G+P
Sbjct: 28855 IIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPV 28914
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
P + W DG I +EI+ + L + A R RG Y ++AKN G A V
Sbjct: 28915 PRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVK 28974
Query: 370 VTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSR 427
V P + T + +TL W+ P +DG + +YI+E T W L
Sbjct: 28975 VQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCE 29034
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T LI G+EY+FR+ A + +G+ P +S PV
Sbjct: 29035 AQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPV 29070
Score = 125 bits (301), Expect = 1e-27
Identities = 110/402 (27%), Positives = 178/402 (44%), Gaps = 24/402 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
RP+PP + SD +++ LKW P DGG+P+ GY +E G WIR +V
Sbjct: 14218 RPSPP----VNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLV 14273
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-V 194
+TGLE +KY +RV+A N G S+ SE+ LT +D A EP + + +D +
Sbjct: 14274 PELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLT--ADDAFVEPTMDLSAFKDGL 14331
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ + + V +G P PT W D + + R + T + + L+ SD+G
Sbjct: 14332 EVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGI 14391
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TI 312
NR + + + A P ++ D ++ T G P +
Sbjct: 14392 YTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVV 14451
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VT 369
E R T ++ +F+V + K +++ A+N G A++ V
Sbjct: 14452 EKREVSRKTWT-KVMDFVTDLEFTVPDLVQGKEY---LFKVCARNKCGPGEPAYVDEPVN 14507
Query: 370 VTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL---KA 423
++ P PDPP NV + S+ L W+PP +DGG ++ YIVE G + W+ +
Sbjct: 14508 MSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP 14567
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ K VT L EG Y +R+KA + G S PS + ++
Sbjct: 14568 VAETKMEVT--GLEEGKWYAYRVKALNRQGASKPSRPTEEIQ 14607
Score = 124 bits (299), Expect = 2e-27
Identities = 104/397 (26%), Positives = 171/397 (43%), Gaps = 18/397 (4%)
Query: 71 WKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT 130
+K+A PPG P I I +D ++ITL W+ +DGG+ + GY VE + EW
Sbjct: 28085 YKAADPIDPPGPPAKIRI-ADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTV 28143
Query: 131 APPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
+ +R E V++ L+P Y FRV+A+N G E+++ + + E + +
Sbjct: 28144 STKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 28203
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
V A + V+ + F G P PT+ W KD+ + S R +I +S+S+L Q+
Sbjct: 28204 LRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTR 28263
Query: 250 SDEGEIKCTATNRGGH----AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+D G+ T N G V+ L AA + + G + T+ ++
Sbjct: 28264 NDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV-----TLLWDPPLI 28318
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG----- 360
+P I + + +S + K+ +++ A+N IG
Sbjct: 28319 DGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC 28378
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
E T V P P R++S+ SV L W P DGG + Y+VE G W
Sbjct: 28379 ETTEP--VKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW 28436
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
A S+ + + L E S +FR+ A++ G+S P
Sbjct: 28437 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDP 28473
Score = 124 bits (298), Expect = 2e-27
Identities = 102/393 (25%), Positives = 168/393 (42%), Gaps = 20/393 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + + + +A + W P DGG+P+ Y V+ W T +
Sbjct: 20714 PGPPVNVTVKEISKDSAY-VTWEPPIIDGGSPIINYVVQKRDAERKSW-STVTTECSKTS 20771
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ LE Y FRV A N+ G + E D + +ASQ P PV ++ V+
Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIGDPGETRDAV-----KASQTPGPVVDLKVRSVSK-S 20825
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S S I + D + ++ + S + E + +
Sbjct: 20826 SCSIGWKKPHSDGGSRIIGYVVD-FLTEENKWQRVMKSLSLQYSA-KDLTEGKEYTFRVS 20883
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL-----LYEINETIFLKTTIVGKPTPTIE 313
A N G T + + + A + P GL L + N LK I GKP P++
Sbjct: 20884 AENENGEG-TPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVS 20942
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W+ P+ TD R+ + + + L ++ ++SD G+Y I KN+ G + V
Sbjct: 20943 WKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGK 21002
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNV 431
P P + +++TL W PP DDGG ++ NYI+E + N W+ ++ +KT
Sbjct: 21003 PGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTF 21062
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L EG EY FR+ AE+ YG+ +S P+
Sbjct: 21063 RVTRLHEGMEYTFRVSAENKYGV-GEGLKSEPI 21094
Score = 124 bits (298), Expect = 2e-27
Identities = 112/426 (26%), Positives = 181/426 (42%), Gaps = 43/426 (10%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR- 137
PPG P P ++D + +L W +DGG + GY VE ++G WI+ LR
Sbjct: 21599 PPGPPSN-PHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI 21657
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKRLEDVTA 196
+ V+ L+ KY FR++A+ND G + + DV V + A E ++R V A
Sbjct: 21658 TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA 21717
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V G P+P + W KD+ + R I ES ++L+ + D G+
Sbjct: 21718 --GLSIRIFVPIKGRPAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFV 21773
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
T N G + + P + L+ T + K + T+ W
Sbjct: 21774 MTIENPAGKKSGFVNVRVLDTP----------------GPVLNLRPTDITKDSVTLHWDL 21817
Query: 317 ---DGHPIITDDRIEISITPKFS----VLKIHSAKRSDRG-----EY--QIQAKNI--IG 360
DG IT+ +E + S K H G EY ++ A+N IG
Sbjct: 21818 PLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIG 21877
Query: 361 EDTAAFL-VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
E T V + P PP ++++ +V+L W P DGG K+ Y++E R G +
Sbjct: 21878 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 21937
Query: 420 WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI--DMDFLA 477
W T + + +L EG EY F++ A + G SAP ES PV + + + ++D
Sbjct: 21938 WTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDLRG 21996
Query: 478 VEARII 483
+ +++
Sbjct: 21997 IYQKLV 22002
Score = 124 bits (298), Expect = 2e-27
Identities = 101/391 (25%), Positives = 172/391 (43%), Gaps = 19/391 (4%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH 149
+D +++TL W DGG+ + Y VE R + + TA + +TGL
Sbjct: 21804 TDITKDSVTLHWDLPLIDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGC 21862
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+Y FRV A N+ G +E ++ + S + PP + + D+T
Sbjct: 21863 EYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDSLN-IMDITKSTVSLAWPKPKHD 21918
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G S + + S + T ITT + ++ + +E + A N G + +
Sbjct: 21919 G-GSKITGYVIEAQRKGSDQWTHITTVKGLECVV-RNLTEGEEYTFQVMAVNSAGRSAPR 21976
Query: 270 AR---LCLEAA--PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
+ E P+L Y+ ++ + + I ++ ++G+P PT+ W+ +
Sbjct: 21977 ESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQT 22036
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR 384
R+ T ++L I+ RSD G Y + A+NI+GE + V P PP
Sbjct: 22037 QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFD 22096
Query: 385 QVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLFDLIEGSEY 442
+V VT W+PP +DGG + NY+VE +T W++ A T +T L G EY
Sbjct: 22097 EVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEY 22156
Query: 443 KFRIKAESPYGM-----SAPSSESSPVRIPG 468
+FR+KA++ YG+ SA + P ++PG
Sbjct: 22157 QFRVKAQNRYGVGPGITSACIVANYPFKVPG 22187
Score = 123 bits (296), Expect = 4e-27
Identities = 102/392 (26%), Positives = 167/392 (42%), Gaps = 21/392 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PP ++ I D ++T+ W DGG+ + GY VE WI+ +
Sbjct: 24746 PGPPKSLEVTNIAKD----SMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRIT 24801
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L +TGL H+Y+FRV+A N G S + V + D + P + D T
Sbjct: 24802 DLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT-VYYKACDPVFKPGPPTNAHIVDTTK 24860
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH--QILPSDEGE 254
+ G S + + + + +T V F ++ E +
Sbjct: 24861 NSITLAWGKPIYDG-GSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYK 24919
Query: 255 IKCTATNRGG-------HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
I+ A N+ G K LEA P+L + G++ + + G+
Sbjct: 24920 IRVCALNKVGLGEATSVPGTVKPEDKLEA-PELDLDSELRKGIVVRAGGSARIHIPFKGR 24978
Query: 308 PTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
PTP I W R +G D+++I ++ L I + R+D G+Y ++ +N G +A
Sbjct: 24979 PTPEITWSREEGE---FTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFV 25035
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V V P PP+N++V S L WEPP DGG KV NY+++ + + +
Sbjct: 25036 TVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSK 25095
Query: 427 -RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
KT+ + +L EG+ Y FR+ AE+ +G+ P
Sbjct: 25096 CSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 25127
Score = 122 bits (295), Expect = 5e-27
Identities = 109/402 (27%), Positives = 167/402 (41%), Gaps = 24/402 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + ++TL W P DGG+ ++ Y VE R + + T +
Sbjct: 22879 PGPPQDLKV-KEVTKTSVTLTWDPPLLDGGSKIKNYIVE-KRESTRKAYSTVATNCHKTS 22936
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L+ Y FRV A N+ G +E T S +AS+ P P L DVT
Sbjct: 22937 WKVDQLQEGCSYYFRVLAENEYGIGLPAE-----TAESVKASERPLPPGKITLMDVTR-N 22990
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + S + + + S + T + T + ++ +E + +
Sbjct: 22991 SVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITG-LIQGEEYSFRVS 23049
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKPTPTIE 313
A N G + + A L P ++ LL+ E + + +G+PTP +
Sbjct: 23050 AQNEKGISDPRQLSVPVIAKDLVIPPAFK--LLFNTFTVLAGEDLKVDVPFIGRPTPAVT 23107
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W D P+ R+ T S+L I A R D G Y ++ N GE V V
Sbjct: 23108 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 23167
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTNV 431
P PP V + S+TL W PP DGG + NYIVE T W + + T +T +
Sbjct: 23168 PGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTI 23227
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSA-----PSSESSPVRIPG 468
L G EY+FRI AE+ YG S P+ P ++PG
Sbjct: 23228 KACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPG 23269
Score = 122 bits (294), Expect = 7e-27
Identities = 87/391 (22%), Positives = 161/391 (41%), Gaps = 8/391 (2%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P ++ + +D ++L+W+ DGG + GY +E + +W + ++
Sbjct: 29180 PPGPPTVVKV-TDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKT 29238
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+T L+ +Y+FRV+A+N G + E++ + + E + +
Sbjct: 29239 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRA 29298
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ + + G P+PT W K D + S R I T +S S L +D G+ T
Sbjct: 29299 GASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGKYTLT 29356
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
N G + + P P ++D + + T+ ++ + +
Sbjct: 29357 VENNSGSKSITFTVKVLDTPGPPGPITFKD--VTRGSATLMWDAPLLDGGARIHHYVVEK 29414
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL---VTVTAPPD 375
IS + K++ +++ A N G + + T P
Sbjct: 29415 REASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA 29474
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD 435
PPR + V S L W P DGG ++ Y++E + G + W++A +++ T+
Sbjct: 29475 PPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVER 29534
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
L+E +EY+FR+KA++ G S P S V I
Sbjct: 29535 LVEKTEYEFRVKAKNDAGYSEPREAFSSVII 29565
Score = 122 bits (293), Expect = 9e-27
Identities = 96/402 (23%), Positives = 161/402 (40%), Gaps = 11/402 (2%)
Query: 68 NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW 127
+V +++ PPG P P ++D ++++L W+ +DGGAP++GY VE + EW
Sbjct: 25918 SVFYRACDALYPPGPPSN-PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW 25976
Query: 128 IRTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
PP L+ + +T L+ +Y FR+ A+N G + L + V+ +R
Sbjct: 25977 TTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSV-VAQERIEPPEIE 26035
Query: 187 FIKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
L V L + + VT G P P + W K E + R I S ++L+
Sbjct: 26036 LDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEK--AEGILTDRAQIEVTSSFTMLVID 26093
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ D G T N G + + +P P + + + T+ + ++
Sbjct: 26094 NVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSA--PVNLTIREVKKDSVTLSWEPPLI 26151
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
+ + I+ + +I + + +++ A N G A
Sbjct: 26152 DGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA 26211
Query: 366 FL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
V V+ PP PP V++ + T+ WE P DGG K+ Y+VE G W
Sbjct: 26212 ETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 26271
Query: 423 AITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ T+ L G EY FR+ A + G S P PV
Sbjct: 26272 CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 26313
Score = 120 bits (289), Expect = 3e-26
Identities = 104/398 (26%), Positives = 166/398 (41%), Gaps = 22/398 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ + + + +A L W P DGGA ++ Y ++ R + + +
Sbjct: 25043 PGPPQNLAVKEVRKDSAF-LVWEPPIIDGGAKVKNYVID-KRESTRKAYANVSSKCSKTS 25100
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP-PVFIKRLEDVTALE 198
+ L Y FRV A N+ G V TV + +A++ P P L DV+
Sbjct: 25101 FKVENLTEGAIYYFRVMAENEFGVG-----VPVETVDAVKAAEPPSPPGKVTLTDVSQTS 25155
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
+ G + + + + + + +I + + + E + +
Sbjct: 25156 ASLMWEKPEHDG--GSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVK 25213
Query: 259 ATNRGGHA------VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
A N G + V L P L+ P + E + ++ ++G+P P I
Sbjct: 25214 AYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS---IQAGEDLKIEIPVIGRPRPNI 25270
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ R+ + T +VL I + D G+Y + A N G T V V
Sbjct: 25271 SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLE 25330
Query: 373 PPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRKTN 430
P PP +V V + WEPPA GGC++ NYIVE T W + + T +T
Sbjct: 25331 KPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT 25390
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVRIP 467
+ + L G+EY+FRI AE+ YG SAP S++ V+ P
Sbjct: 25391 IKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYP 25428
Score = 120 bits (288), Expect = 4e-26
Identities = 106/409 (25%), Positives = 170/409 (41%), Gaps = 23/409 (5%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP P++ I D ++ + W DGG+ + Y VE WI+
Sbjct: 22580 GPPDPPKNPEVTTITKD----SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 22635
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKR 190
+ ++GL H+Y+FR+ A N G S S S TV P V
Sbjct: 22636 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTS 22695
Query: 191 LEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
++ N + + +G +D+++I + T + + L +Q
Sbjct: 22696 RSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQ--- 22752
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE-DGLLYEINE-----TIFLKTT 303
E +I+ A N G A P + E D L ++ T+ L
Sbjct: 22753 --EYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP 22810
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
I G+P P ++W D + D+ I T +++L + + R D G+Y + +N G +
Sbjct: 22811 IKGRPAPEVKWARDHGESL--DKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKS 22868
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
A V V P PP+++ V SVTL W+PP DGG K+ NYIVE + +
Sbjct: 22869 AFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTV 22928
Query: 424 ITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI 471
T+ KT+ + L EG Y FR+ AE+ YG+ P+ + V+ R +
Sbjct: 22929 ATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPL 22977
Score = 119 bits (286), Expect = 6e-26
Identities = 106/396 (26%), Positives = 172/396 (43%), Gaps = 21/396 (5%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG Q + + + + N T+ W +GG+ + + VE + W A + R
Sbjct: 18929 PGPCQNLKVTNVTKENC-TISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR-- 18985
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL-SDVLTVSS-DRASQEPPVFIK-RLEDVTA 196
L+ L ++Y FRV A N VG E + +L ++ DR + + I + +
Sbjct: 18986 LIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVY 19045
Query: 197 LENDKVEFHVTFSGIPSPTIAWFK--DDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L+ + ++ + K DD+E R + + T ++ + + + E
Sbjct: 19046 LKWRRPDYDGGSPNLSYHVERRLKGSDDWE-----RVHKGSIKETHYMV-DRCVENQIYE 19099
Query: 255 IKCTATNRGGHA---VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+ N GG + T+ + E K + L + +TI L+ + GKP P
Sbjct: 19100 FRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPE 19159
Query: 312 IEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ W D + R++I S + AKRSD G+Y + A N G A V
Sbjct: 19160 VAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVN 19219
Query: 370 VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITSRK 428
V P P RN+ + T+ W+PP DDGGC++ NYI+E T VW + T
Sbjct: 19220 VLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLT 19279
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ LIEG+EY FR++AE+ G + P +ES PV
Sbjct: 19280 PGTTVTRLIEGNEYIFRVRAENKIG-TGPPTESKPV 19314
Score = 118 bits (285), Expect = 9e-26
Identities = 101/385 (26%), Positives = 162/385 (42%), Gaps = 14/385 (3%)
Query: 91 DDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHK 150
D N+I L W P +DGG+ ++GY VE GS +W+ P+ ++ +TGLE
Sbjct: 14525 DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKW 14583
Query: 151 YQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSG 210
Y +RV ALN G S S ++ + + + E + +K L +T K+E T +G
Sbjct: 14584 YAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTG 14643
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W K D + +R I S + SD G A N G A A
Sbjct: 14644 KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT--A 14701
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI--E 328
+ + K P ++ + NE+ L + + TD + +
Sbjct: 14702 VVEVNVLDKPGPPAAFD--ITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHK 14759
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT---APPDPPRNVSVT 383
+S T K + K + +++ A+N+ +GE A +T PP PP + +
Sbjct: 14760 LSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPS 14819
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSE 441
+VTL W P DDGG + Y VE + W++ + + T + L +
Sbjct: 14820 DITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKK 14879
Query: 442 YKFRIKAESPYGMSAPSSESSPVRI 466
Y+FR+ AE+ G PS + P+ I
Sbjct: 14880 YRFRVLAENLAGPGKPSKSTEPILI 14904
Score = 118 bits (285), Expect = 9e-26
Identities = 86/381 (22%), Positives = 166/381 (43%), Gaps = 11/381 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + ++ D + LKW P +DGG P++ Y +E T W++
Sbjct: 15111 PGPPYALAVV-DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 15169
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + + QF+V A N+ G + SE +++L++ + PP+ + + ++
Sbjct: 15170 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTD--AGRKH 15227
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD--ESTSVLLFHQILPSDEGEIKC 257
+ + SP I + + + + + + + + + ++P E ++
Sbjct: 15228 IAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRV 15287
Query: 258 TATNRGG----HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
A N G +++ + + K + D ++ E E + + P PT+
Sbjct: 15288 RAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIE-GEKLSIPVPFRAVPVPTVS 15346
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG + DR+ + + L++ + R+D G Y I +N +G TA+ V V
Sbjct: 15347 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 15406
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTNVT 432
P P +++ + S L WEPP DGG + +Y++E G ++ ++ K + T
Sbjct: 15407 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 15466
Query: 433 LFDLIEGSEYKFRIKAESPYG 453
+ DLI EY FR+KA + G
Sbjct: 15467 VKDLIPNGEYFFRVKAVNKVG 15487
Score = 118 bits (284), Expect = 1e-25
Identities = 104/394 (26%), Positives = 159/394 (40%), Gaps = 25/394 (6%)
Query: 86 IPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPIVLRPELVLTG 144
IP S+ N+ITL WA DGG+ ++ Y +E ST W++ + + +TG
Sbjct: 29084 IPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 29143
Query: 145 LEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED---VTALENDK 201
L ++Y+F V A N G S +S ++ PP +K + +LE K
Sbjct: 29144 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 29203
Query: 202 VEFHVTFSGI-------PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
F I + W K + E R +T ++ F + G+
Sbjct: 29204 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGK 29263
Query: 255 -IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C T G RL AP+L ++ + +I L G+PTPT
Sbjct: 29264 GDSCEVT---GTIKAVDRL---TAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAV 29317
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W + R +I T FS L + + R+D G+Y + +N G + F V V
Sbjct: 29318 WSKPDSNLSL--RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDT 29375
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P PP ++ S TL W+ P DGG ++ +Y+VE W + S K +
Sbjct: 29376 PGPPGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW--QVISEKCTRQI 29433
Query: 434 F---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
F DL EG Y FR+ A + YG+ P P+
Sbjct: 29434 FKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPI 29467
Score = 118 bits (283), Expect = 1e-25
Identities = 98/396 (24%), Positives = 161/396 (40%), Gaps = 14/396 (3%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + I +D ++L W P +DGGA + Y +E S W
Sbjct: 14118 PGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLS 14176
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T + +Y FRV A N +G S + + V+ PPV + + +
Sbjct: 14177 ATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQ 14236
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE---IK 256
K E + G SP + + + E + I + L +++ ++G +
Sbjct: 14237 LKWEPPLKDGG--SPILGYIIERCE--EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYR 14292
Query: 257 CTATNRGGHAVTKARLC-LEAAPKLRYPRQ----YEDGLLYEINETIFLKTTIVGKPTPT 311
+A N+ G + L L A P ++DGL + I + G P PT
Sbjct: 14293 VSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPT 14352
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
W + T DR+++ ++ L I ++RSD+G Y ++ +N + + V V
Sbjct: 14353 ATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVI 14412
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SRKTN 430
A P P+ + SV L WEPP DDGG + Y+VE W K +
Sbjct: 14413 ARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLE 14472
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ DL++G EY F++ A + G P+ PV +
Sbjct: 14473 FTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNM 14508
Score = 118 bits (283), Expect = 1e-25
Identities = 104/406 (25%), Positives = 169/406 (41%), Gaps = 33/406 (8%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP+++ ++ + W P +GG+P+ GY +E GS W R + +
Sbjct: 16526 PGPPGKPKVLARTK----GSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPIT 16581
Query: 137 RPELVLTGLEPPH-----KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ L P KYQFR A+N G SE SD V+ D P +
Sbjct: 16582 KVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP-EVAGDPIFPPGPPSCPEV 16640
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE---STSVLLFHQIL 248
+D T + + + SP + + E ++ + + +T + +
Sbjct: 16641 KDKTK-SSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLK 16699
Query: 249 PSDEGEIKCTATNRGGHAV---TKARLC---LEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + A N G + T + ++ P++ +D L+ + I +
Sbjct: 16700 ELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPA 16759
Query: 303 TIVGKPTPTIEWRHDG----------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I G+PTP W DG H I D ++E + SV+ I KRS G+Y
Sbjct: 16760 VIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETA--ENSSVIIIPECKRSHTGKYS 16817
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
I AKN G+ TA V V P PP+++ V+ S L W+ P DDGG ++ Y++E
Sbjct: 16818 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 16877
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W K T + DL+ +Y FR++AE+ +G+ P
Sbjct: 16878 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPP 16923
Score = 117 bits (282), Expect = 2e-25
Identities = 120/420 (28%), Positives = 182/420 (43%), Gaps = 38/420 (9%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
KP K A P PPG+P+ I + N++TL+W T+DGG+ + GY VE L
Sbjct: 23352 KPSKVSECYVARDPCDPPGRPEAIIVTR----NSVTLQWKKPTYDGGSKITGYIVEKKEL 23407
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG-HSNYSELSDVLT----VSS 177
W++ + ++ +TGL H+Y+FRV A N G S SE + +T V
Sbjct: 23408 PEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDP 23467
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
R S +P K V A E+ KV+ + G P PTI W K D E+ ++ R I + +
Sbjct: 23468 PRISMDPK--YKDTIVVHAGESFKVDADI--YGKPIPTIQWIKGDQELSNTARLEIKSTD 23523
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+ L + D G A N G + + L P E ++ I+
Sbjct: 23524 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV-----LDRPGPPEGPVV--ISGV 23576
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEY- 351
K T+ KP P + D I + R + + L K + EY
Sbjct: 23577 TAEKCTLAWKP-PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYT 23635
Query: 352 -QIQAKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKV 405
+I A N +GE + V P PD P+ VT S+ + WE PA DGG ++
Sbjct: 23636 FRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEI 23695
Query: 406 GNYIVEYY-RTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
Y++E + G W K + + + + LIE +Y+FR+ AE+ G+S PS S+
Sbjct: 23696 LGYVLEKRDKEGIRWTRCHKRLIG-ELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSA 23754
Score = 117 bits (281), Expect = 3e-25
Identities = 98/400 (24%), Positives = 165/400 (41%), Gaps = 21/400 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP +I + + ++TL W+ DGG+ + GY +E S W+R V
Sbjct: 26910 PSPPTSLEITSVTKE----SMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVY 26965
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-VT 195
+ TGL +Y++RV A N G S SE S ++ PP K ++ T
Sbjct: 26966 DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKT 27025
Query: 196 ALENDKVEFHVTFSG---IPSPTIAWFKDD-----YEIFSSRRTAITTDESTSVLLFHQI 247
+ V+ F G I T+ + K D I S R T T T+ +
Sbjct: 27026 TITIAWVK--PLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFR 27083
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ S ++ + K R E P + L+ + + + G+
Sbjct: 27084 VKSVNKVGASDPSDSSDPQIAKER---EEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGR 27140
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P P + W + T R + T + L I +A R+D G+Y + +N++ + +
Sbjct: 27141 PVPNVLWSKPDTDLRT--RAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLV 27198
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V V P PP N++V +S L W+ P +DGG V NY +E W+ +
Sbjct: 27199 VKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC 27258
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + +L EG+ Y FR+ E+ +G+ P+ V+I
Sbjct: 27259 NRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 27298
Score = 116 bits (280), Expect = 3e-25
Identities = 107/397 (26%), Positives = 165/397 (41%), Gaps = 17/397 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K+A P+PPGK L+D + +L W HDGG+ + GY VE G+ +W A
Sbjct: 25135 KAAEPPSPPGKVT----LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 25190
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V V+TGL +YQFRV A N+ G S+ L V ++ D Q
Sbjct: 25191 ESKVC--NAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG-VPVIAKDLTIQPSLKLPFNT 25247
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ A E+ K+E V G P P I+W KD + + R + +++VL + D
Sbjct: 25248 YSIQAGEDLKIEIPVI--GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDD 25305
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ TATN G A + + P D + + + G
Sbjct: 25306 FGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTG-GCQI 25364
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE----DTAAFL 367
+ + T +S T + +KI K +++I A+N G+ D+ A +
Sbjct: 25365 SNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVI 25424
Query: 368 VTVT-APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
V P PP VT + + W P +DGG K+ Y +E +W+K +
Sbjct: 25425 VQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKT 25484
Query: 427 --RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T L EG EY+F++ AE+ G+ PS S
Sbjct: 25485 PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 25521
Score = 115 bits (277), Expect = 8e-25
Identities = 110/423 (26%), Positives = 178/423 (42%), Gaps = 24/423 (5%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIVLRPELVLTGL 145
PI+++ ++ + W HDGG P+ Y +E S W R T PI + + L
Sbjct: 17945 PIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDL 18003
Query: 146 EPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFH 205
+Y+FRV+A N++G + S S + A PPV + + D T D
Sbjct: 18004 LEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAI-DTTCNSVDLTWQP 18062
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVLLFHQILPSDEGE---IKCTATN 261
G S + + + ++ R A T ES + ++ +G+ + A N
Sbjct: 18063 PRHDG-GSKILGYIVEYQKVGDEEWRRANHTPESCPETKY-KVTGLRDGQTYKFRVLAVN 18120
Query: 262 RGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
G + V + L + P+L ++ +T+ L I G P P + W+
Sbjct: 18121 AAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWK 18180
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ T RI+ +TP S L+I +A D G Y + +N G T + V V P
Sbjct: 18181 KEDRDAPTKARID--VTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG 18238
Query: 376 PPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNVTLF 434
PPR++ V+ S L W+ P DDGG + NY+VE W + TS+K +
Sbjct: 18239 PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAK 18298
Query: 435 DLIEGSEYKFRIKAESPYGMS------APSSESSPVRIPGRAIDMDFLAVEARIINEALT 488
L EG++Y FR+ AE+ YG P P+ PG D+ + V+ ++
Sbjct: 18299 HLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 18358
Query: 489 RED 491
+ D
Sbjct: 18359 KPD 18361
Score = 115 bits (276), Expect = 1e-24
Identities = 102/402 (25%), Positives = 161/402 (40%), Gaps = 27/402 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P I + + ITLKW P DGG+ + GY +E R G+ W+R V
Sbjct: 28784 PPGTPDYIDVTRE----TITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSEC 28838
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI---KRLEDVT 195
+ +TGL P +Y+FR+ A N VG + S + ++ D PP+ + + +
Sbjct: 28839 QYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDE--NVPPIVEFGPEYFDGLI 28896
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + G P P + WFKD EI IT ++ L G
Sbjct: 28897 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956
Query: 256 KCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
A N G A + ++ ++ P K+ P ++ + + T++ + P +
Sbjct: 28957 TVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTN--ITGEKMTLWWDAPLNDGCAPITHY 29014
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ--IQAKNIIG------EDTAAF 366
+ T I K + K + EYQ + A N G D
Sbjct: 29015 IIEKRE--TSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVA 29072
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
+ T P D P + S+TL W P DGG ++ YI+E W+K I+
Sbjct: 29073 QIQYTVP-DAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISK 29131
Query: 427 RKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
R + T F L EG+EY+F + AE+ G+ S S ++
Sbjct: 29132 RPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIK 29173
Score = 113 bits (273), Expect = 2e-24
Identities = 107/411 (26%), Positives = 173/411 (42%), Gaps = 28/411 (6%)
Query: 64 KPRKNVHWKSAGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL 122
K KN A P PPG P+ I + + N ITL+W +DGG+ + GY VE L
Sbjct: 24434 KASKNSECYVARDPCDPPGTPEPIMV----KRNEITLQWTKPVYDGGSMITGYIVEKRDL 24489
Query: 123 GSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRAS 181
W++ + V+ + ++GL +Y+FRV A N G S S+ + +T +
Sbjct: 24490 PDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVEL 24549
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+ K + + + G P PTI W + D EI S R I + ++
Sbjct: 24550 PRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKAL 24609
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ + D G+ A+N G + + L P E + ++ K
Sbjct: 24610 LIVKDAIRIDGGQYILRASNVAGSKSFPVNVKV-----LDRPGPPEGPV--QVTGVTSEK 24662
Query: 302 TTIVGKPTPTIEWRHD-GHPII---TDDRIEISITPKFSV---LKIHSAKRSDRGEYQIQ 354
++ P P + D H ++ R+ ++ V LK+ + ++I
Sbjct: 24663 CSLTWSP-PLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIM 24721
Query: 355 AKNI--IGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYI 409
A N +GE + V + P P PP+++ VT S+T+ W P DGG ++ YI
Sbjct: 24722 AVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYI 24781
Query: 410 VEYYRTGWNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPS 458
VE W+K R T++ L L E EY+FR+ AE+ G+ PS
Sbjct: 24782 VEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPS 24832
Score = 113 bits (271), Expect = 4e-24
Identities = 100/398 (25%), Positives = 169/398 (42%), Gaps = 22/398 (5%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P++ I +++LKW+ +DGGA + GY VE L W++ +
Sbjct: 26614 PPGQPEVTNITR----KSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQET 26669
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+T L +Y+FRV A N S SE + + V D + +K + +
Sbjct: 26670 YFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVK 26729
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ ++ + +G P P I+W KD EI RT I + ++ ++L + D G+
Sbjct: 26730 AGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVL 26789
Query: 258 TATNRGG-HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT---IE 313
T N G +V L+ P + +GL E + + G +E
Sbjct: 26790 TLKNVAGTRSVAVNCKVLDKPGPPAGPLEI-NGLTAEKCSLSWGRPQEDGGADIDYYIVE 26848
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVT 371
R H T E+ +T K+ + + +++ N +GE + +
Sbjct: 26849 KRETSHLAWTICEGELQMTS----CKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKAL 26904
Query: 372 AP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-- 426
P P PP ++ +T +S+TL W P DGG ++ YI+E W++
Sbjct: 26905 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 26964
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V L EG EY++R+ AE+ G+S P SE+SP+
Sbjct: 26965 YDLRVKSTGLREGCEYEYRVYAENAAGLSLP-SETSPL 27001
Score = 113 bits (271), Expect = 4e-24
Identities = 101/384 (26%), Positives = 162/384 (42%), Gaps = 16/384 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I + + +A+ L W +DGGAP++ Y +E W+ R
Sbjct: 27205 PGPPTNITVQDVTKESAV-LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCN-RLS 27262
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+T L+ Y FRV+ N+ G +E + + ++ + E +D +L
Sbjct: 27263 YKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTW 27322
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
K E H S I + + + + A +T S L + E + A
Sbjct: 27323 LKPE-HDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLR-----ENSEYFFRVFA 27376
Query: 260 TNRGGHAVTKARLC-LEAAPKLRYP----RQYEDGLLY-EINETIFLKTTIVGKPTPTIE 313
N+ G + + L + +L P + + +Y + + I GKP P +
Sbjct: 27377 ENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVT 27436
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
DG P+ R IT + + + + +D G Y+I A N G A + V
Sbjct: 27437 LSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDR 27496
Query: 374 PDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AITSRKTNV 431
P PP V + ++SVTL WEPP DGG +V NYI+ T VW + + T +T +
Sbjct: 27497 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMM 27556
Query: 432 TLFDLIEGSEYKFRIKAESPYGMS 455
+ L G EY+FRIKAE+ +G+S
Sbjct: 27557 KVMKLTTGEEYQFRIKAENRFGIS 27580
Score = 112 bits (270), Expect = 6e-24
Identities = 111/415 (26%), Positives = 173/415 (41%), Gaps = 27/415 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT-APPI---V 135
PG P P +S N++T+ W +DGG+P+ GY +E S W R PI
Sbjct: 17244 PGAPDK-PTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT 17302
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L +TGL YQFRV A+N G S SD T + D + P F ++ D T
Sbjct: 17303 LGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPAT-ARDPIAPPGPPF-PKVTDWT 17360
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEG 253
D +E+ S + + Y+ D+ + L+ +
Sbjct: 17361 KSSAD-LEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFY 17418
Query: 254 EIKCTATNRGGHA----VTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
+ + +A N G VT + +P L+ D ++ I + + GK
Sbjct: 17419 KFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 17478
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P PT+ W + + + IE + V+K + +RS +G Y + AKN GE +
Sbjct: 17479 PPPTVTWNMNERTLPQEATIETTAISSSMVIK--NCQRSHQGVYSLLAKNEAGERKKTII 17536
Query: 368 VTVTAPPDPPRNVSVTRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK-AIT 425
V V P P + + ++S L W P DDGG + NY++E + W T
Sbjct: 17537 VDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYT 17596
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMS--APSSES----SPVRIPGRAIDMD 474
+ N T+ LI+G Y FRI AE+ GM +SE+ P+ +P R D++
Sbjct: 17597 VTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE 17651
Score = 111 bits (267), Expect = 1e-23
Identities = 96/403 (23%), Positives = 157/403 (38%), Gaps = 15/403 (3%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
V++K+ PG P I+ D N+ITL W +DGG+ + GY VE + EW
Sbjct: 24836 VYYKACDPVFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQ 24894
Query: 129 RTAPPIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF 187
P LR ++ L +Y+ RV ALN VG + + + + E +
Sbjct: 24895 IVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLD 24954
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ + + H+ F G P+P I W +++ E + + I + + L
Sbjct: 24955 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNC 25012
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI-NETIFL--KTTI 304
+D G+ N G ++ L P ++ + E+ ++ FL + I
Sbjct: 25013 DRNDAGKYILKLENSSG-----SKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPI 25067
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT- 363
+ + D +S + K+ + +++ A+N G
Sbjct: 25068 IDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVP 25127
Query: 364 --AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
V PP PP V++T S +L WE P DGG +V Y+VE G W
Sbjct: 25128 VETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS 25187
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
S+ N + L G EY+FR+KA + G S P PV
Sbjct: 25188 IVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPV 25230
Score = 111 bits (267), Expect = 1e-23
Identities = 87/391 (22%), Positives = 158/391 (40%), Gaps = 19/391 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P+++ + + + W +DGG+ + GY +E S W + ++
Sbjct: 26514 PGPPGTPKVVHATK----STMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIA 26569
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ ++GL+ Y++RV A N G S+ + + P +
Sbjct: 26570 DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVS 26629
Query: 197 LENDKVEFH--VTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH-QIL 248
L+ K + +G P W K +Y + + T E T + ++
Sbjct: 26630 LKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYT--NIQETYFEVTELTEDQRYEFRVF 26687
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
+ + + G + K + P++ ++ D ++ + E + + I G+P
Sbjct: 26688 ARNAADSVSEPSESTGPIIVKDDV---EPPRVMMDVKFRDVIVVKAGEVLKINADIAGRP 26744
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P I W DG I R EI T ++L + R D G+Y + KN+ G + A
Sbjct: 26745 LPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNC 26804
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW-LKAITS 426
V P PP + + + +L W P +DGG + YIVE T W +
Sbjct: 26805 KVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGEL 26864
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ T+ + L++G+EY FR+ + YG+ P
Sbjct: 26865 QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEP 26895
Score = 110 bits (264), Expect = 3e-23
Identities = 105/398 (26%), Positives = 165/398 (41%), Gaps = 26/398 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG+P+ I I N +TLKW +DGG+ + GY VE L W++ + VL
Sbjct: 25532 PPGRPEAIVITR----NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLET 25587
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGH-SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
E ++GL +Y+FRV A N G+ S S+ S +T + + + K + +
Sbjct: 25588 EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVH 25647
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ G P P + W KD E+ ++ R I + + L+ + +D G+
Sbjct: 25648 AGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI 25707
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
+N GG TK+ + K+ +G L ++ K + P +
Sbjct: 25708 LKLSNVGG---TKS---IPITVKVLDRPGPPEGPL-KVTGVTAEKCYLAWNPPLQDGGAN 25760
Query: 317 DGHPIITD---DRIE-ISITPKFSVLKIHSAKRSDRGEY--QIQAKNI--IGEDTAAFLV 368
H II R+ ++ + L K EY ++ A N IGE + V
Sbjct: 25761 ISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPV 25820
Query: 369 TVT---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT 425
T PP PP V+ S+ + W P DDGG ++ YI+E W K
Sbjct: 25821 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 25880
Query: 426 SRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSES 461
T++ L L EG Y+FR+ AE+ G+ PS S
Sbjct: 25881 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 25918
Score = 109 bits (263), Expect = 4e-23
Identities = 92/394 (23%), Positives = 166/394 (42%), Gaps = 15/394 (3%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P +P+ + + + N +TL W P +DGG+ + Y +E +G+ ++ + +L +
Sbjct: 17644 PERPEDLEV-KEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRK 17702
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ GL+ Y++RV+A+N VG S + +T + A P + + + +T
Sbjct: 17703 YTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAP--PTLHLDFRDKLTIRVG 17760
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
+ +SG P P ++WFKD+ ++ RT I T +T L + SD G+
Sbjct: 17761 EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV 17820
Query: 260 TNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
N G ++ + P P +++ + + I K + + + +
Sbjct: 17821 ENSTGSRKGFCQVNVVDRPGPPVGPVSFDE--VTKDYMVISWKPPLDDGGSKITNYIIEK 17878
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP----- 373
+ D + ++ + K+ ++I A+N+ G ++ A
Sbjct: 17879 KEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRV 17938
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
PD P VT S + W P DGG + NYI+E T W + T
Sbjct: 17939 PDAPDQPIVTEVTKDSALVTWNKP-HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTK 17997
Query: 434 F---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
F DL+EG +Y+FR+ AE+ G+ PS S PV
Sbjct: 17998 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPV 18031
Score = 109 bits (261), Expect = 7e-23
Identities = 98/399 (24%), Positives = 159/399 (39%), Gaps = 26/399 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG+ ++ + N T+KW DGG+ + GY VE GS +W L
Sbjct: 26223 PLPPGRVTLVDVTR----NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTL 26278
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
E ++GL +Y FRVAA+N+ G S+ +L V ++ D + +V A
Sbjct: 26279 --EATISGLTAGEEYVFRVAAVNEKGRSDPRQLG-VPVIARDIEIKPSVELPFHTFNVKA 26335
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
E K++ V F G P T+ W KD + + R +++ ++ + L + D G +
Sbjct: 26336 REQLKID--VPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYE 26393
Query: 257 CTATNRGGHAVTKARLCLEAAP----KLRYPRQYEDGLLYEINETIF-----LKTTIVGK 307
+N G + + P +R D + N + + IV K
Sbjct: 26394 LCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEK 26453
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
T H + I+I S + + G K+ E +A
Sbjct: 26454 KETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYG------KSSYSESSAVVA 26507
Query: 368 VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--IT 425
+PP PP V ++ + W+ P +DGG +V Y +EY +W KA I
Sbjct: 26508 EYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKIL 26567
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T + + L EG Y++R+ AE+ G+ S PV
Sbjct: 26568 IADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 26606
Score = 108 bits (260), Expect = 9e-23
Identities = 99/399 (24%), Positives = 157/399 (39%), Gaps = 30/399 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECN-RLGSTE----WIR-TAP 132
PPG P ++ D ++ITL W +DGGAP+ GY VE ++ W R A
Sbjct: 19423 PPGPPTNFRVV-DTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 19481
Query: 133 PIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 192
++R E +T L+ +Y+FRV A N VG +EL + + E + +
Sbjct: 19482 AQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRK 19541
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
V + G P+P + W K + R+ + ++ + L+ D
Sbjct: 19542 LVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNV-VRKGQVDLVDTMAFLVIPNSTRDDS 19600
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ T N G + + L P D + ++ +T + P
Sbjct: 19601 GKYSLTLVNPAGEKAVFVNVRV-----LDTPGPVSDLKVSDVTKT---SCHVSWAPPEND 19652
Query: 313 EWRHDGHPII----TDDRIEISITPKFSVLKIHSAKRSDRGEY--QIQAKNIIGEDTAAF 366
H I+ D + ++TP+ H EY ++ A N G
Sbjct: 19653 GGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTD 19712
Query: 367 L---VTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--N 418
+ V + P PDPPR + VT S TL W PP DGG K+ YI Y +
Sbjct: 19713 VPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPAD 19772
Query: 419 VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
W + + ++ + L EG +YKFR+ A + G+S P
Sbjct: 19773 RWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLP 19811
Score = 108 bits (260), Expect = 9e-23
Identities = 90/402 (22%), Positives = 163/402 (40%), Gaps = 11/402 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIR-TAPPIV 135
PAPP P++ D ++++L W +DGG+P+ GY VE R S W+R P +
Sbjct: 20516 PAPPAFPKVY----DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNL 20571
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +YQFRV A+N +G+S+ S++ D E + + +
Sbjct: 20572 QKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLI 20631
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ +V G P P I W K + + I + + + L + D G+
Sbjct: 20632 LRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKY 20691
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
T N G + + ++ P + + + + + I+ +P I +
Sbjct: 20692 ILTLENSCGK--KEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYV 20749
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTA 372
++ + ++ + + +++ A+N G V +
Sbjct: 20750 VQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQ 20809
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
P P ++ V S ++ W+ P DGG ++ Y+V++ T N W + + S +
Sbjct: 20810 TPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSLSLQYS 20868
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
DL EG EY FR+ AE+ G PS + R A D+D
Sbjct: 20869 AKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLD 20910
Score = 108 bits (260), Expect = 9e-23
Identities = 87/403 (21%), Positives = 162/403 (40%), Gaps = 12/403 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI- 134
+P PP P++I I +++ L W+ +DGG ++GY VE + EW PP
Sbjct: 23764 KPGPPNNPKVIDITR----SSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTG 23819
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
+ + + + L H+Y FR+ A+N G ++++ + V + + + ++ + +
Sbjct: 23820 INKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 23879
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ V G P+P + W K D EI + +T+ S + L+ + D G+
Sbjct: 23880 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGK 23937
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
T N G A + + P + + + + +I + ++ + +
Sbjct: 23938 YTLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNY 23995
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVT 371
+ + + KI + +++ A+N G A + V
Sbjct: 23996 IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVA 24055
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV 431
P PP ++V SV+L W P DGG K+ YIVE W + +
Sbjct: 24056 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 24115
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
+ +L +G EY FR+ A + G S P S + P+ I+ D
Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPD 24158
Score = 107 bits (256), Expect = 3e-22
Identities = 100/405 (24%), Positives = 168/405 (41%), Gaps = 25/405 (6%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K++ P+PP I+ I + ++L W HDGG+ + GY +E R GS +W T
Sbjct: 21887 KASEAPSPPDSLNIMDITK----STVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW--TH 21940
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKR 190
V E V+ L +Y F+V A+N G S E V+ + + ++
Sbjct: 21941 ITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQK 22000
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L A +N KVE V G P PT+ W K D + ++R T ++++L ++ + S
Sbjct: 22001 LVIAKAGDNIKVEIPVL--GRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRS 22058
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D G TA N G + + P P ++++ + + G P
Sbjct: 22059 DSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 22118
Query: 310 P--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI--IGEDTAA 365
+E R + +E++ T + K +++++A+N +G +
Sbjct: 22119 SNYVVEMRQTD----STTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITS 22174
Query: 366 FLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P PP VT S+T+ W P DGG + Y VE +W +
Sbjct: 22175 ACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILW-Q 22233
Query: 423 AITSRKTNVTLF---DLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++ +F L +G Y+FR+ AE+ G S PS S P+
Sbjct: 22234 TVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPM 22278
Score = 107 bits (256), Expect = 3e-22
Identities = 105/399 (26%), Positives = 160/399 (40%), Gaps = 21/399 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K A P PPGK + D N+++L W HDGG+ + Y VE S +W A
Sbjct: 24053 KVAEVPQPPGKITV----DDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 24108
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V + V+T L +Y FRV A+N+ G S+ L+ V V+ D EP V
Sbjct: 24109 R--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA-VPIVAKDLVI-EPDVK-PAF 24163
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ ++ V SG P PTI W KD + + R +T + L + D
Sbjct: 24164 SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 24223
Query: 252 EGEIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG-KPT 309
G+ T N G + L+ + P +++D I + G + T
Sbjct: 24224 GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQIT 24283
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
I + D + D +S T + LK+ K +++I A+N G+ A
Sbjct: 24284 NYIVQKRDTTTTVWD---VVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP 24340
Query: 370 VTA-----PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ A P PP T S+ + W P ++GG V Y +E +W K
Sbjct: 24341 IVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVN 24400
Query: 425 TS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+ T +L EG EY+FR+ AE+ G+ S S
Sbjct: 24401 KTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 24439
Score = 107 bits (256), Expect = 3e-22
Identities = 103/405 (25%), Positives = 172/405 (42%), Gaps = 24/405 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K +P+PP K + I D +++L W HDGG+ + Y VE G W++ A
Sbjct: 27297 KITEKPSPPEKLGVTSISKD----SVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCA 27352
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
+ V++GL +Y FRV A N G S+ EL +L V + P + +K
Sbjct: 27353 --VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPREL--LLPVLIKEQLEPPEIDMKNF 27408
Query: 192 EDVTAL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR--TAITTDESTSVLLFHQI 247
T ++ + SG P P + +D + ++ R T IT + T + +
Sbjct: 27409 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLT--INLKES 27466
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVG 306
+ +D G + TA N G TKA + + + P + E + T+ +
Sbjct: 27467 VTADAGRYEITAANSSG--TTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYD 27524
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--EDTA 364
+ + T E+S T +++K+ + +++I+A+N G +
Sbjct: 27525 GGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID 27584
Query: 365 AFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
+ VTV P P PP VT +S+T+ W P +GG V Y +E +W
Sbjct: 27585 SACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQ 27644
Query: 422 KA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
KA + R T+ + + G Y+FR+ AE+ G+ PS S PV
Sbjct: 27645 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPV 27689
Score = 106 bits (254), Expect = 5e-22
Identities = 97/398 (24%), Positives = 163/398 (40%), Gaps = 19/398 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
APPG P P ++D ++ L+W+P DGG+ + GY VE G EW + V
Sbjct: 17347 APPGPP--FPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 17404
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+LV+TGL+ Y+FRV+A+N G E++DV+ + S + + + +
Sbjct: 17405 TKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVH 17464
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
+ SG P PT+ W ++ + + I T +S ++ S +G
Sbjct: 17465 AGGVIRIIAYVSGKPPPTVTWNMNERTL--PQEATIETTAISSSMVIKNCQRSHQGVYSL 17522
Query: 258 TATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEW 314
A N G + L+ + P + T F G P IE
Sbjct: 17523 LAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEK 17582
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----EDTAAFLV- 368
R T + ++T + + + + ++I A+N IG E + A ++
Sbjct: 17583 RESDRRAWTP--VTYTVTRQNAT--VQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 17638
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR- 427
P+ P ++ V +VTL W PP DGG ++ NY++E G + K
Sbjct: 17639 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 17698
Query: 428 -KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
T+ L EG Y++R+ A + G PS + P+
Sbjct: 17699 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI 17736
Score = 104 bits (249), Expect = 2e-21
Identities = 99/403 (24%), Positives = 156/403 (38%), Gaps = 20/403 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P+ + + SD + L W DGG ++GY +E + W + P
Sbjct: 16839 PGPPKDLKV-SDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCG-STT 16896
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR---LEDVTA 196
V+ L +Y FRV A N G E T +PP+ +K ++
Sbjct: 16897 FVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVH 16956
Query: 197 L--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L + K + + +AW + + R D ++ E E
Sbjct: 16957 LSWKPPKNDGGSPVTHYIVECLAWDPTGTKK-EAWRQCNKRDVEELQFTVEDLVEGGEYE 17015
Query: 255 IKCTATNRGGHAVTKARL--CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ A N G + A + C P + ++ + E + + I G P PT+
Sbjct: 17016 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 17075
Query: 313 EW------RHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
W + D P++ D + + L I ++RSD G Y I A N +G +
Sbjct: 17076 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 17135
Query: 366 FLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI 424
+ V P PP V +TL W PP DDGG K+ NY++E W+
Sbjct: 17136 MRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVS 17195
Query: 425 TS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAP-SSESSPVR 465
+ ++ T+ L+EG EY FRI A++ YG+ P SE R
Sbjct: 17196 SEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETAR 17238
Score = 102 bits (245), Expect = 6e-21
Identities = 95/398 (23%), Positives = 159/398 (39%), Gaps = 24/398 (6%)
Query: 77 PAPPGKPQIIPI-LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
P PPG PI D + TL W DGGA + Y VE W +
Sbjct: 29376 PGPPG-----PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSW-QVISEKC 29429
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
R + L Y FRV+A+N+ G E+ + + + A PP +RL+ V
Sbjct: 29430 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPA---PP---RRLDVVD 29483
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
++ V + I + + S +++ E E
Sbjct: 29484 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEF 29543
Query: 256 KCTATNRGGHAVTKARLC--LEAAPKLRYPRQYEDGLLYEI-----NETIFLKTTIVGKP 308
+ A N G++ + + P++ P G+ ++ + I G+P
Sbjct: 29544 RVKAKNDAGYSEPREAFSSVIIKEPQIE-PTADLTGITNQLITCKAGSPFTIDVPISGRP 29602
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
P + W+ + + DR+ I+ T + L + + R D G Y + +N G T + V
Sbjct: 29603 APKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTV 29662
Query: 369 TVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS- 426
V P P + V+ +S L W P D GG ++ NYIVE +G W +S
Sbjct: 29663 VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV 29722
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
++T + + L + EY FR+ +E+ +G+S P ES+P+
Sbjct: 29723 KRTQIKVTHLTKYMEYSFRVSSENRFGVSKP-LESAPI 29759
Score = 101 bits (241), Expect = 2e-20
Identities = 118/429 (27%), Positives = 176/429 (41%), Gaps = 42/429 (9%)
Query: 65 PRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGS 124
P + + +A P P P I + N + L W P +DGG+P+ Y VEC
Sbjct: 16923 PVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDP 16982
Query: 125 T-----EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDR 179
T W + V + + L +Y+FRV A+N G S S + V R
Sbjct: 16983 TGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS--ATVGPCDCQR 17040
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYE--IFSSRRT 231
P + +K +V E V G+P PT+ WFK D+ E ++ +
Sbjct: 17041 PDMPPSIDLKEFMEVE--EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVN 17098
Query: 232 AITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGL 290
+ D+ T L+ Q SD G TA N G A + RL + P P ++E
Sbjct: 17099 KLVVDD-TCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 17157
Query: 291 LYEINETIFLKTTIVG-KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
++ + F G K T + + + + + +S PK I
Sbjct: 17158 ADQMTLSWFPPKDDGGSKITNYVIEKREAN---RKTWVHVSSEPKECTYTIPKLLEGHEY 17214
Query: 350 EYQIQAKNI--IGE------DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDG 401
++I A+N IGE +TA L +V PD P SVTR S+T++WE P DG
Sbjct: 17215 VFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTR---NSMTVNWEEPEYDG 17271
Query: 402 GCKVGNYIVEYYRTGWNVW-------LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGM 454
G V Y +E T W +KA+T + + LIEGS+Y+FR+ A + G+
Sbjct: 17272 GSPVTGYWLEMKDTTSKRWKRVNRDPIKAMT-LGVSYKVTGLIEGSDYQFRVYAINAAGV 17330
Query: 455 SAPSSESSP 463
S S P
Sbjct: 17331 GPASLPSDP 17339
Score = 97.5 bits (232), Expect = 2e-19
Identities = 102/414 (24%), Positives = 162/414 (39%), Gaps = 38/414 (9%)
Query: 64 KPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLG 123
KP + A RP P P I P L D L W DGG+P+ GY VEC + G
Sbjct: 18714 KPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPG 18773
Query: 124 STEWIRTAPPIVLRP-ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ 182
+ +W R ++R + GL ++Y+FR+ A N VG EL++ +
Sbjct: 18774 TAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPP 18833
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E + + + +T + G P P I W K+ + +R + D L
Sbjct: 18834 EVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVEL 18893
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +D G+ +A N GHA A + + P P Q LK
Sbjct: 18894 QIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPG---PCQN-------------LKV 18937
Query: 303 TIVGKPTPTIEWRH---DGHPIITDDRIEI--------SITPKFSVLKIHSAKRSDRGEY 351
T V K TI W + +G IT+ +E SI ++ A EY
Sbjct: 18938 TNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEY 18997
Query: 352 --QIQAKNIIG------EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++ A+N +G T + P P N+ + + V L W P DGG
Sbjct: 18998 YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGS 19057
Query: 404 KVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
+Y VE G + W + + ++T+ + +E Y+FR++ ++ G S
Sbjct: 19058 PNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGES 19111
Score = 96.3 bits (229), Expect = 5e-19
Identities = 100/405 (24%), Positives = 162/405 (40%), Gaps = 25/405 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P + SD +A+TL W DGG+P+ GY VE + +W+R V
Sbjct: 14809 PPGPPTRLEP-SDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDT 14867
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP--VFIKRLEDVTA 196
+ GL KY+FRV A N G S+ ++ + + PP +K + +
Sbjct: 14868 TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSV 14927
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
N H + I S I K + + + T + L ++ E +
Sbjct: 14928 RLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH----LLPGLMEGQEYSFR 14983
Query: 257 CTATNRGGHAVTKAR----LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP--TP 310
A N+ G + LC E PR E ++ T LK T+ K +P
Sbjct: 14984 VRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE--VINITKNTADLKWTVPEKDGGSP 15041
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-------EDT 363
+ + + + T K + + +++ A+N IG ED+
Sbjct: 15042 ITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDS 15101
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
T T P PP ++V + V L WEPP +DGG + Y++E W+KA
Sbjct: 15102 VLAKDTFTTP-GPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKA 15160
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
N + D+IEG+E +F+++AE+ G+ PS + + I
Sbjct: 15161 GKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSI 15205
Score = 95.9 bits (228), Expect = 7e-19
Identities = 69/237 (29%), Positives = 111/237 (46%), Gaps = 11/237 (4%)
Query: 160 DVGHSNYSELSDVL--TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
D+G +DV T A + PP F+K+L D++ + +V+ T G ++
Sbjct: 8392 DIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV 8451
Query: 218 WFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-LE 275
WFKD EI S I+ E+ + L F ++ P++ G+ C N G A L LE
Sbjct: 8452 WFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE 8511
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
A + P + + +T L+ T+ G P + +W DG + +D++ +IS K
Sbjct: 8512 PATIVEKP----ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 8567
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGED--TAAFLVT-VTAPPDPPRNVSVTRQVDKS 389
S LKI + SD G Y + +N +G+D TA+ V+ T PP R + T + S
Sbjct: 8568 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGS 8624
Score = 95.9 bits (228), Expect = 7e-19
Identities = 67/251 (26%), Positives = 112/251 (44%), Gaps = 12/251 (4%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W +++ + + + ++ L I P D+GE + A ++ +A+L L
Sbjct: 13869 VQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEA----RAKLELA 13924
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAPK++ Q L+ ++ + + + P EW + P+ T I T +
Sbjct: 13925 AAPKIKTADQ---DLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQ 13978
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ +I AK+ D+G Y+I +N G+ + V P P RN+ VT D V+L WE
Sbjct: 13979 TSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWE 14038
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKAI-TSRKTNVTLFDLIEGS-EYKFRIKAESPYG 453
P DGG K+ Y+VE W+ A + T+ L +G EY FR+ A + G
Sbjct: 14039 EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVG 14098
Query: 454 MSAPSSESSPV 464
P +PV
Sbjct: 14099 TGEPVETDNPV 14109
Score = 95.5 bits (227), Expect = 9e-19
Identities = 99/394 (25%), Positives = 161/394 (40%), Gaps = 32/394 (8%)
Query: 99 LKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAAL 158
L W+ DGG+ + G+ +E W + P R + +TGL +Y+FRV A
Sbjct: 16142 LNWSDPEDDGGSEITGFIIERKDAKMHTWRQ--PIETERSKCDITGLLEGQEYKFRVIAK 16199
Query: 159 NDVGHSNYSELSDVLTVS--SDRASQEPPVFIKRLEDVTALE--NDKVEFHVTFSGIPSP 214
N G E+ +L V S E + +R + L+ + G
Sbjct: 16200 NKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIE 16259
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
K D+E + +R TT L HQ+ E + A N G + L +
Sbjct: 16260 KRRHDKPDFERVN-KRLCPTTSFLVENLDEHQMY-----EFRVKAVNEIGESEPSLPLNV 16313
Query: 275 -----EAAPKLRYPRQYE-DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII--TD-- 324
E P ++ D + + E + + + G P P IEW + I TD
Sbjct: 16314 VIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDAL 16373
Query: 325 --DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ E+S + + L I A R D+G Y + A N +G V V P PPRN++V
Sbjct: 16374 QITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAV 16433
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWN--VWLKAI-TSRKTNVTLFDLIEG 439
T +S L W+ P D+GG ++ +Y+++ W + T+ + ++ LI
Sbjct: 16434 TDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPN 16493
Query: 440 SEYKFRIKAESPYGMSAPSSE-----SSPVRIPG 468
+Y+FR++A + YG+S P R+PG
Sbjct: 16494 GQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPG 16527
Score = 95.1 bits (226), Expect = 1e-18
Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP FI+ L+ V ++ VE +G P + W K++ EI SS++ +T S
Sbjct: 5879 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 5938
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + PSD GE +C +N GG R+ L+ P + ++ E+ + + +
Sbjct: 5939 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPS--FIKKIENTTTV-LKSSATFQ 5995
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG- 360
+T+ G P +I W D + DD + IS + L+I S G Y QAKN G
Sbjct: 5996 STVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGV 6055
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVD 387
E AFL+ +P + V + VD
Sbjct: 6056 ERCYAFLLV----QEPAQIVEKAKSVD 6078
Score = 91.9 bits (218), Expect = 1e-17
Identities = 49/193 (25%), Positives = 92/193 (47%), Gaps = 3/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+++ + + L V F G P +++WFK E+ R ++ ++S +
Sbjct: 8699 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 8758
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + S GE C +N G A L ++A K + ++ D + E + + L+
Sbjct: 8759 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK--FVKRLNDYSI-EKGKPLILE 8815
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T G P ++ W+ +G + R I+ T K ++L+I S+ D G+Y +N G+
Sbjct: 8816 GTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGK 8875
Query: 362 DTAAFLVTVTAPP 374
D+ + + + PP
Sbjct: 8876 DSCSAQILILEPP 8888
Score = 91.5 bits (217), Expect = 1e-17
Identities = 55/182 (30%), Positives = 85/182 (46%), Gaps = 7/182 (3%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
I + L+ GKP P+I W DG P+ + + S T L I +AK+ G+Y +
Sbjct: 28504 IGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV 28563
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N + V PP P+ + SV L W+ P D+GG ++ Y +E
Sbjct: 28564 ILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEK 28623
Query: 413 YRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV-----RI 466
T W +S +T + +L++ +EY+FR++AE+ YG+S P S V RI
Sbjct: 28624 RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRI 28683
Query: 467 PG 468
PG
Sbjct: 28684 PG 28685
Score = 91.1 bits (216), Expect = 2e-17
Identities = 55/193 (28%), Positives = 87/193 (45%), Gaps = 3/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
QEPP F+K E + L V F G P + WF+ E+ R I +++ +
Sbjct: 6817 QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 6876
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I S GE C +N G A RL ++ P R + + E ++I L+
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE-PAAFLKRLSDHSV--EPGKSIILE 6933
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+T G ++ W+ DG I T ++ I T K +L+I ++ + D G+Y + +N G
Sbjct: 6934 STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 6993
Query: 362 DTAAFLVTVTAPP 374
D LV+ PP
Sbjct: 6994 DVCGALVSTLEPP 7006
Score = 90.6 bits (215), Expect = 3e-17
Identities = 107/409 (26%), Positives = 169/409 (41%), Gaps = 50/409 (12%)
Query: 90 SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLT--GLEP 147
SD ++ L W P DGG P+ Y +E G +I P + +L T L P
Sbjct: 15416 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYI---PVMSGENKLSWTVKDLIP 15472
Query: 148 PHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVT 207
+Y FRV A+N VG Y EL + + + +PPV ++ + + TA E + +
Sbjct: 15473 NGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE-VHNPTA-EAMTITWKPP 15530
Query: 208 FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG---EIKCTATNRGG 264
S + + + +I +E +L + +EG + + A N G
Sbjct: 15531 LYDGGSKIMGYIIE--KIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAG 15588
Query: 265 HAV-TKARLCLEAAPKLRYPRQY-EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH--- 319
+ ++A +A + P+ L + + I L +I G P PTI W D +
Sbjct: 15589 ISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 15648
Query: 320 ---------PIITDDRIEIS--------ITPKFSV---------LKIHSAKRSDRGEYQI 353
P++ + E+ +T + S+ L++ + R D G Y I
Sbjct: 15649 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 15708
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY 413
+ +N G A V+V P PP N SV WEPP DDGG ++ NY +E
Sbjct: 15709 KVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKK 15768
Query: 414 -----RTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ W V + K +VT LIEG EY FR++AE+ +G P
Sbjct: 15769 DKTKPDSEWIVVTSTLRHCKYSVT--KLIEGKEYLFRVRAENRFGPGPP 15815
Score = 89.4 bits (212), Expect = 6e-17
Identities = 62/218 (28%), Positives = 99/218 (45%), Gaps = 16/218 (7%)
Query: 74 AGRPA-PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAP 132
AG P PPG P P + D ++I+L W P DGG+P++GY VE G+T+W R
Sbjct: 16625 AGDPIFPPGPPSC-PEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNE 16683
Query: 133 P--IVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK- 189
P ++ E V+ L+ KY+FRV A+N+ G S S+ + + + +EP VFI
Sbjct: 16684 PDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATD--IQEEPEVFIDI 16741
Query: 190 -RLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTDESTS 240
+ + ++ G P+P +W D D + T E++S
Sbjct: 16742 GAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSS 16801
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
V++ + S G+ TA N+ G R+ + P
Sbjct: 16802 VIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVP 16839
Score = 88.6 bits (210), Expect = 1e-16
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+++ T + +Y F V NDVG S+ +VL + PP F K+L+ + +++
Sbjct: 5564 KIISTEKKDSGEYTFEVQ--NDVGRSSCKARINVLDLII------PPSFTKKLKKMDSIK 5615
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
++ +G +I WFKDD EI +S + + ++T+ L Q+ +D G C+
Sbjct: 5616 GSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCS 5675
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
ATN+ GH L ++ P Q +D N + LK + G TI+W D
Sbjct: 5676 ATNKAGHNQCSGHLTVKEPPYFVEKPQSQD---VNPNTRVQLKALVGGTAPMTIKWFKDN 5732
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + + + L++ +AK +D G Y Q N +G T+ + V PP
Sbjct: 5733 KELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 5788
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/213 (27%), Positives = 97/213 (45%), Gaps = 5/213 (2%)
Query: 182 QEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
QEPP FIK+LE ++ D+ + G P + W+KD+ EI S + ++ +S +
Sbjct: 8229 QEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA 8288
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
VL H + D G+ C A N G A + L ++ P R + L + L
Sbjct: 8289 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK---GADVHL 8345
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P + W D + + + +I + + I + +D GEYQ +A N +G
Sbjct: 8346 ECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVG 8405
Query: 361 EDTAAFLVTVTAPPDPPRNVS-VTRQVDKSVTL 392
DT + + APP + +S ++ V K V L
Sbjct: 8406 SDTCVGSIALKAPPRFVKKLSDISTVVGKEVQL 8438
Score = 87.8 bits (208), Expect = 2e-16
Identities = 92/410 (22%), Positives = 167/410 (40%), Gaps = 33/410 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+ + ++ + ITL W +GG+P++GY +E R ++ R +
Sbjct: 16221 PPTSPERLTY-TERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTT 16279
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL----EDV 194
++ L+ Y+FRV A+N++G S S +V+ + D + PP RL + +
Sbjct: 16280 SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVV-IQDD---EVPPTIKLRLSVRGDTI 16335
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEI------FSSRRTAITTDESTSVLLFHQIL 248
+ V +G+P P I W K++ I + ++ E+ + L + +
Sbjct: 16336 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 16395
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKP 308
D+G TA+NR G +E + PR + + + +
Sbjct: 16396 REDKGTYTVTASNRLGSVFRNVH--VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGG 16453
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA-KRSDRGEYQIQAKNI----IGEDT 363
+ + D + + E +V K + K G+Y+ + + + I ++
Sbjct: 16454 SEITHYVIDKRD-ASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 16512
Query: 364 AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ V + P P PP V + S+ + W PP D+GG + Y +E G W
Sbjct: 16513 KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYW 16572
Query: 421 LKAITSRKTNVTL----FD---LIEGSEYKFRIKAESPYGMSAPSSESSP 463
+ + T V L F+ L+EG +Y+FR A + G+ PS S P
Sbjct: 16573 SRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDP 16622
Score = 87.0 bits (206), Expect = 3e-16
Identities = 50/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+ + A+ + VEF G P I WFKDD E+ S + I + STS
Sbjct: 6254 KEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSF 6313
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + + S G+ C TN G L + PK + ++ E + + ++ L+
Sbjct: 6314 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPK--FVKKLEASKIVKAGDSSRLE 6371
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P + W + H + D+ ++ +V+++++ D G++ +A+N G
Sbjct: 6372 CKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGS 6431
Query: 362 DTAAFLVTVTAPP 374
+ + V V PP
Sbjct: 6432 TSCSTKVIVKEPP 6444
Score = 86.6 bits (205), Expect = 4e-16
Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 6/198 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTS 240
+EPP F+ +L +T + + E + G + W K+ E+ S IT E+ +
Sbjct: 6534 KEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA 6593
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIF 299
L F + P++ G+ C N GG A L LE A + + + + ET
Sbjct: 6594 TLQFAKAEPANAGKYICQIKNDGGMEENMATLMVLEPAVIV----EKAGPMTVTVGETCT 6649
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ + G P ++EW DG + + + + S K S L+I S +R D G Y Q +N +
Sbjct: 6650 LECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 6709
Query: 360 GEDTAAFLVTVTAPPDPP 377
G+ + +V V+ PP
Sbjct: 6710 GKSSCTAVVDVSDRAVPP 6727
Score = 86.6 bits (205), Expect = 4e-16
Identities = 51/169 (30%), Positives = 80/169 (47%), Gaps = 4/169 (2%)
Query: 298 IFLKTTIVGKPTPTIEWRHDG-HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
I L + G+P P + WR G ++ ++++ T F V I ++ R D G+Y +
Sbjct: 19551 IRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLV--IPNSTRDDSGKYSLTLV 19608
Query: 357 NIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG 416
N GE V V P P ++ V+ S + W PP +DGG +V +YIVE
Sbjct: 19609 NPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREAD 19668
Query: 417 WNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
W +KT+ + +L+ G+EY FR+ A + YG P+ PV
Sbjct: 19669 RKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPV 19717
Score = 83.4 bits (197), Expect = 4e-15
Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 8/233 (3%)
Query: 159 NDVGHSNYSELSDVL--TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTI 216
+DVG + ++V T S +EPP F+K+L D + L D VE G ++
Sbjct: 7450 SDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISV 7509
Query: 217 AWFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-L 274
W KD E+ S T I+ ++ + L S+ G+ C N G A L L
Sbjct: 7510 VWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 7569
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
E A + P + + L+ + G P + +W DG + D + I+ K
Sbjct: 7570 EPARIIEKP----EPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINK 7625
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
+ LKI A+ SD+G Y + KN +G+ V V+ PP + + V+
Sbjct: 7626 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVN 7678
Score = 82.2 bits (194), Expect = 9e-15
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP FIK++E ++L F T G T+ W KD EI +T + + +
Sbjct: 5410 REPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 5469
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIF 299
L I +G+ C A N G A L ++ + E+ + ++ +
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIT-----EEAVSIDVTQGDPAT 5524
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ G T +W DG + + +IS+T S+LKI S ++ D GEY + +N +
Sbjct: 5525 LQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDV 5584
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
G + + V PP +++D
Sbjct: 5585 GRSSCKARINVLDLIIPPSFTKKLKKMD 5612
Score = 82.2 bits (194), Expect = 9e-15
Identities = 47/196 (23%), Positives = 87/196 (44%), Gaps = 3/196 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP F+KRL D + + T++G P +++W KD+Y I S R +IT E +++
Sbjct: 7851 KEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 7910
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + C N G + +A + + P P ++ + + I E L+
Sbjct: 7911 LEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAV---IGEPATLQ 7967
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P I W + + + ++ + L I+ SD GEY +A N +G
Sbjct: 7968 CKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGA 8027
Query: 362 DTAAFLVTVTAPPDPP 377
++ ++ + PP
Sbjct: 8028 VASSAVLVIKERKLPP 8043
Score = 81.8 bits (193), Expect = 1e-14
Identities = 58/235 (24%), Positives = 104/235 (44%), Gaps = 11/235 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++ LE + +A N GH+ + S LTV +EPP F+++ + N
Sbjct: 5659 LEISQLEGTDSGTYTCSATNKAGHN---QCSGHLTV------KEPPYFVEKPQSQDVNPN 5709
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
+V+ G TI WFKD+ E+ S ++ D++++ L +D G C
Sbjct: 5710 TRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQL 5769
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
+N G A +KA L ++ P ++ ++ L+ ++ + I G P + W DG+
Sbjct: 5770 SNDVGTATSKATLFVKEPP--QFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGN 5827
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I + IS + +I A+ + G Y +A+N G + + + V PP
Sbjct: 5828 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 5882
Score = 81.0 bits (191), Expect = 2e-14
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 1/192 (0%)
Query: 184 PPVFIKRL-EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
PP F KRL E V E + + +G T+AW+K++ EI + IT +T VL
Sbjct: 9175 PPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 9234
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ +D G C +N G A+ + + ++ K Q+ + E + L
Sbjct: 9235 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSC 9294
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G I+W G I DR S +VL++ ++D G+Y +A N+ G D
Sbjct: 9295 HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSD 9354
Query: 363 TAAFLVTVTAPP 374
T VT+ P
Sbjct: 9355 TTKSKVTIKDKP 9366
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 3/209 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+K+++D+ AL V G ++ W K I + ++ +V
Sbjct: 4848 KEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 4907
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ + S G+ C A N G + L ++ K+ + + + + L+
Sbjct: 4908 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII---ERAELIQVTAGDPATLE 4964
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T+ G P +W DG P++ + IS + LK +SA+ D G+Y + N +G
Sbjct: 4965 YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 5024
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
+ TV P R VD V
Sbjct: 5025 SSCETTFTVLDRDIAPFFTKPLRNVDSVV 5053
Score = 79.8 bits (188), Expect = 5e-14
Identities = 66/228 (28%), Positives = 106/228 (46%), Gaps = 12/228 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLE-DVTALENDKVEFHV 206
H Q+ +A N +G ++ S LT R ++ P F IK + DV A E+ E HV
Sbjct: 7168 HSGQYSCSASNPLGTASSSAR---LTA---REPKKSPFFDIKPVSIDVIAGESADFECHV 7221
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
T G I W KD+ EI IT +T L ++ D G+ C ATN G
Sbjct: 7222 T--GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 7279
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
+ A+L ++ PK + ++ E + + E+I L+ I G P + W + + +
Sbjct: 7280 MCSAQLSVKEPPK--FVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWK 7337
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+S ++L I+ A D G+Y +A N +G+ + + +TV APP
Sbjct: 7338 YNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 7385
Score = 79.8 bits (188), Expect = 5e-14
Identities = 52/206 (25%), Positives = 96/206 (46%), Gaps = 7/206 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP+F K+ + L+ V G P ++W+KD E+ S ++ I ++ +
Sbjct: 8323 KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 8382
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ + +D GE +C ATN G + L+A P R+ ++ D + + + + L+
Sbjct: 8383 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP--RFVKKLSD-ISTVVGKEVQLQ 8439
Query: 302 TTIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
TTI G ++ W D I+ + D I IS + + L+ + ++ G+Y Q KN G
Sbjct: 8440 TTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 8499
Query: 361 EDTAAFLVTVTAPP---DPPRNVSVT 383
++V P + P ++ VT
Sbjct: 8500 MQECFATLSVLEPATIVEKPESIKVT 8525
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 2/196 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP F+K+LE V D +G P ++W+K D ++ + + + + L
Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINETIFLK 301
+F+Q+ +D GE C A N G L + E + RQ D + + +
Sbjct: 8946 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFD 9004
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G ++ W DG P+ ++ S + L I RS G+Y A N IG
Sbjct: 9005 CAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 9064
Query: 362 DTAAFLVTVTAPPDPP 377
+++ + +T +PP
Sbjct: 9065 ASSSARLILTEGKNPP 9080
Score = 77.8 bits (183), Expect = 2e-13
Identities = 49/196 (25%), Positives = 85/196 (43%), Gaps = 2/196 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP F+ LE + A D V +G P T++W+K D ++ + + + L
Sbjct: 7004 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 7063
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINETIFLK 301
+F+++ +D GE C A N G A +K + E + RQ +D + + + L
Sbjct: 7064 VFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKD-IEQTVGLPVTLT 7122
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G + W DG + D+ ++ S + LKI S G+Y A N +G
Sbjct: 7123 CRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGT 7182
Query: 362 DTAAFLVTVTAPPDPP 377
+++ +T P P
Sbjct: 7183 ASSSARLTAREPKKSP 7198
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 3/209 (1%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A +EPP FIK++E+ T + F T +G P +I W KDD + I+ +S
Sbjct: 5970 ALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV 6029
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
+ L + G C A N G A L ++ ++ + D + +
Sbjct: 6030 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVD---VTEKDPMT 6086
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ + G P ++W DG I+ +S + +I S + D G+Y + +N
Sbjct: 6087 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
G + + V PP ++DK
Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDK 6175
Score = 76.6 bits (180), Expect = 5e-13
Identities = 94/401 (23%), Positives = 158/401 (39%), Gaps = 33/401 (8%)
Query: 89 LSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPP 148
+ D ++ L W DGG+ + Y VE G W I E+ ++ L+
Sbjct: 28398 MKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQ 28455
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
+FRV A N+ G S+ + + TV + E + VT V + +
Sbjct: 28456 SVLEFRVFAKNEKGLSDPVTIGPI-TVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPY 28514
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN---RGGH 265
G P P+I+W KD + S + E+ L G+ N R
Sbjct: 28515 KGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAV 28574
Query: 266 AVTKARLCLEAAPK--LRYPRQYEDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPII 322
+T L + PK +R+ D ++ + + G+ T +IE R
Sbjct: 28575 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVP---EDNGGGEITCYSIEKRETSQ--- 28628
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPP 377
T+ ++ S + + K+ + + +++++A+N G + A P PP
Sbjct: 28629 TNWKMVCSSVAR-TTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP 28687
Query: 378 RNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTL 433
+ ++L W+ P DGG +V + VE +W K TS R+ T
Sbjct: 28688 GKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRAT- 28746
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPSSES------SPVRIPG 468
L+EG +Y+FR+ AE+ G+S+PS S SPV PG
Sbjct: 28747 -GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPG 28786
Score = 76.2 bits (179), Expect = 6e-13
Identities = 63/265 (23%), Positives = 99/265 (37%), Gaps = 8/265 (3%)
Query: 116 QVECNRLGS----TEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+++C GS W + I + +E + +ND G+ +
Sbjct: 5058 RLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNS 5117
Query: 172 VLTVSSDRAS--QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
V + S A QEPP F+ + L V TF G TI WFK + E+ S
Sbjct: 5118 VGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGG 5177
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
IT + S L + + SD G C +N G A L ++ + + E
Sbjct: 5178 SCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK--EPATFVEKLEPS 5235
Query: 290 LLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
L + + L + G P I W + I + +S +VL++ D G
Sbjct: 5236 QLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSG 5295
Query: 350 EYQIQAKNIIGEDTAAFLVTVTAPP 374
EY +A+N G D + +V V P
Sbjct: 5296 EYMCEAQNEAGSDHCSSIVIVKESP 5320
Score = 76.2 bits (179), Expect = 6e-13
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 6/195 (3%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP +++ E + D T +G P + WFKD E+ S + I+ S L
Sbjct: 8511 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 8570
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE---AAPKLRYPRQYEDGLLYEINETIF 299
+ PSD G N G A L + P + +GL ++
Sbjct: 8571 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS---GSSVV 8627
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++ + G P ++ W H+G+ I + + + ++T L ++ + SD G+Y A N+
Sbjct: 8628 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 8687
Query: 360 GEDTAAFLVTVTAPP 374
G D + +TV PP
Sbjct: 8688 GSDECSAPLTVREPP 8702
Score = 76.2 bits (179), Expect = 6e-13
Identities = 45/190 (23%), Positives = 77/190 (40%), Gaps = 3/190 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F ++L++ L V G P +++WF + EI S R+ T ++T L
Sbjct: 8608 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 8667
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ + SD G+ C ATN G A L + P Q D + + +
Sbjct: 8668 VNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSF---VQKPDPMDVLTGTNVTFTSI 8724
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P ++ W ++ DR +S+ + L++ S GEY N G+ +
Sbjct: 8725 VKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKAS 8784
Query: 364 AAFLVTVTAP 373
+ + AP
Sbjct: 8785 CTTHLYIKAP 8794
Score = 75.8 bits (178), Expect = 8e-13
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 5/211 (2%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
+ Y +S T++ A PP F+ R + +T +F T +G P W KD
Sbjct: 4459 NEYGSVSCTATLTVTEAY--PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 4516
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ S I+ E+ +L + D G C A+N+ G + +A L + P +
Sbjct: 4517 ALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP--HFI 4574
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA 343
++ E + IN+ + L+ + T+ W DG + +I K + L+I A
Sbjct: 4575 KELEP-VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLA 4633
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
K D G Y A N G + + VTV PP
Sbjct: 4634 KLKDSGTYVCTASNEAGSSSCSATVTVREPP 4664
Score = 75.8 bits (178), Expect = 8e-13
Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 10/242 (4%)
Query: 158 LNDVGHSNYSELSDVLTVSSDRAS-------QEPPVFIKRLEDVTALENDKVEFHVTFSG 210
L DV S E + +++ + +AS + P F+KRL D + + + TF+G
Sbjct: 8761 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTG 8820
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P ++ W K+ + S+R ITT E +++L D G+ C N G A
Sbjct: 8821 TPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSA 8880
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
++ + P + +Q E + + ++ L+ + G P + W + ++
Sbjct: 8881 QILILEPPY--FVKQLEP-VKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMH 8937
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
+ L + +D GEY +A+N +GE +A+ +TV PP R V ++V
Sbjct: 8938 FRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV 8997
Query: 391 TL 392
L
Sbjct: 8998 GL 8999
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/204 (26%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PPVF ++ V AL+ V SG P + W KD ++ +S++ IT+ + L
Sbjct: 7384 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLH 7443
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ SD GE C ATN G + + P R+ ++ D I + + L+
Sbjct: 7444 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP--RFVKKLSDTSTL-IGDAVELRAI 7500
Query: 304 IVGKPTPTIEWRHD-GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G ++ W D G I + IS + L++ S + S+ G+Y Q KN G
Sbjct: 7501 VEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMR 7560
Query: 363 TAAFLVTVTAPP---DPPRNVSVT 383
+ ++TV P + P ++VT
Sbjct: 7561 ECSAVLTVLEPARIIEKPEPMTVT 7584
Score = 73.3 bits (172), Expect = 4e-12
Identities = 48/191 (25%), Positives = 80/191 (41%), Gaps = 10/191 (5%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+PAPP + ++ D ++ L W HDGG+ + GY +E + GS W+
Sbjct: 29472 QPAPPRRLDVV----DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQ 29527
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED-- 193
L + L +Y+FRV A ND G+S E + + + EP + + +
Sbjct: 29528 L--TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQI--EPTADLTGITNQL 29583
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T V SG P+P + W ++ + + R +ITT + + L + D G
Sbjct: 29584 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 29643
Query: 254 EIKCTATNRGG 264
T N G
Sbjct: 29644 RYFLTLENTAG 29654
Score = 72.9 bits (171), Expect = 6e-12
Identities = 59/208 (28%), Positives = 79/208 (37%), Gaps = 8/208 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS-RRTAITTDESTSVLL 243
PVF+ + LE F + G P P WF D +I + + ++ T L+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
PSD GE A NR G + L +EA P E I E + +K
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMK 1576
Query: 302 TTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
G P P I W + I+ +I I T + LKI S D Y A N
Sbjct: 1577 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636
Query: 360 GEDTAAFLVTVT---APPDPPRNVSVTR 384
G DT V V A P+P R + + R
Sbjct: 1637 GRDTTRCKVNVEVEFAEPEPERKLIIPR 1664
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 3/192 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+E P F K + + L+ V +G P I WFKD+ + S R+ +
Sbjct: 5317 KESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVS 5376
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + + +D GE +C TN G ++ AR+ L P + L T +
Sbjct: 5377 LQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR---GGTAAFQ 5433
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T+ G T+ W D I DD I ++ + L + + G+Y QAKN G
Sbjct: 5434 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 5493
Query: 362 DTAAFLVTVTAP 373
+ L++V P
Sbjct: 5494 QRCSALLSVKEP 5505
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/211 (22%), Positives = 86/211 (40%), Gaps = 3/211 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP F+KRL D + + T++G ++ W KD + I +S + I T E T +
Sbjct: 6910 KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCI 6969
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L D G+ C N G V A + P + + E L + +++ L+
Sbjct: 6970 LEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPY--FVTELEP-LEAAVGDSVSLQ 7026
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P T+ W + T + L + +D GEY +A+N IG
Sbjct: 7027 CQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGT 7086
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
++ + + PP + ++++V L
Sbjct: 7087 ASSKTVFRIQERQLPPSFARQLKDIEQTVGL 7117
Score = 72.1 bits (169), Expect = 1e-11
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 12/234 (5%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L +T ++ + A+NDVG SD + S++ +EPP FIK LE +
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVG-------SD--SCSTEIVIKEPPSFIKTLEPADIVRG 4772
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
SG I+WFKD +I SS++ + + +S L +D GE +C
Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G A L+ P + ++ +D L+ +T+ L+ + G ++ W
Sbjct: 4833 ANEVGKCGCMATHLLKEPP--TFVKKVDD-LIALGGQTVTLQAAVRGSEPISVTWMKGQE 4889
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
I D +I++S + +VL I + S G+Y A+N G T+ + V P
Sbjct: 4890 VIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEP 4943
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/219 (24%), Positives = 98/219 (44%), Gaps = 6/219 (2%)
Query: 167 SELSDVLTVSSDRASQEPPVFIKRLEDVTALEN-DKVEFHVTFSGIPSPTIAWFKDDYEI 225
S ++ + S++ +EP F+++LE L+ D + +G P I WF +D EI
Sbjct: 5208 SNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI 5267
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S + ++ EST+VL + D GE C A N G + + ++ +P + ++
Sbjct: 5268 KESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY--FTKE 5325
Query: 286 YED-GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAK 344
++ +L E + + L + G P I W D + + + + I L+I
Sbjct: 5326 FKPIEVLKEYD--VMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFV 5383
Query: 345 RSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+D GEYQ + N +G + VT+ PP + + T
Sbjct: 5384 AADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIEST 5422
Score = 71.7 bits (168), Expect = 1e-11
Identities = 60/238 (25%), Positives = 91/238 (38%), Gaps = 15/238 (6%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L L+G+E H ++ A ND G S L V +EP + + +
Sbjct: 5470 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV---------KEPATITEEAVSIDVTQG 5520
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
D V FSG T WFKD E+ + I+ ++ S+L D GE
Sbjct: 5521 DPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEV 5580
Query: 260 TNRGGHAVTKAR---LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
N G + KAR L L P + D + I L+ + G +I+W
Sbjct: 5581 QNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIK---GSFIDLECIVAGSHPISIQWFK 5637
Query: 317 DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D I ++ + S + L+I + +D G Y A N G + + +TV PP
Sbjct: 5638 DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPP 5695
Score = 70.9 bits (166), Expect = 2e-11
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPGKP + D ++ L W HDGGA + Y +E + G+ EW+R A +
Sbjct: 14911 PWPPGKPTV----KDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPT 14966
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK 189
L L GL +Y FRV A+N G S SE SD + PP +++
Sbjct: 14967 TQHL-LPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 15018
Score = 70.1 bits (164), Expect = 4e-11
Identities = 58/228 (25%), Positives = 101/228 (44%), Gaps = 12/228 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLE-DVTALENDKVEFHV 206
H Q+ +A N +G ++ S + S+ + PP F +K + D+ E+ + HV
Sbjct: 8109 HIGQYNCSASNPLGTAS----SSAKLILSEH--EVPPFFDLKPVSVDLALGESGTFKCHV 8162
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
T G I W KD+ EI +T E+T+ L ++ D G+ C A+N G
Sbjct: 8163 T--GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD 8220
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A L ++ P R+ ++ E + + +E + I G P + W D I +
Sbjct: 8221 SCSAHLGVQEPP--RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSK 8278
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+S +VL++H+ D G+Y +A N G +++ + V PP
Sbjct: 8279 FRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 8326
Score = 69.7 bits (163), Expect = 5e-11
Identities = 57/240 (23%), Positives = 97/240 (40%), Gaps = 8/240 (3%)
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRA----- 180
+W + P+V + ++ + +F A L+D G + ++V + S +
Sbjct: 4976 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 5035
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
P F K L +V ++ N +G ++WFKD EI +S R I E T+
Sbjct: 5036 RDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTA 5095
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ +D G C ATN G + L ++ P +D L + L
Sbjct: 5096 SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVL---PGSAVCL 5152
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K+T G TI W +++ I+ S L+++ K SD G Y + N+ G
Sbjct: 5153 KSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 5212
Score = 69.7 bits (163), Expect = 5e-11
Identities = 42/123 (34%), Positives = 58/123 (47%), Gaps = 4/123 (3%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
APP PP VT S L+W PP DGG KV YIVEY G W K R T
Sbjct: 17347 APPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 17405
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTR 489
+ + L EG+ YKFR+ A + G+ P + + + R + D L ++A + + +
Sbjct: 17406 KLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKDRLVSPD-LQLDASVRDRIVVH 17464
Query: 490 EDG 492
G
Sbjct: 17465 AGG 17467
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/94 (31%), Positives = 47/94 (50%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + L++VT +E + V SG PSPT+ W+++DY+I SS IT + L+
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G C+A N G T L ++ +
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 69.3 bits (162), Expect = 7e-11
Identities = 71/304 (23%), Positives = 119/304 (39%), Gaps = 19/304 (6%)
Query: 81 GKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE----WIRTAPPIVL 136
G + +L+ EP I K P T G P + +EC G+ E W + +
Sbjct: 7558 GMRECSAVLTVLEPARIIEKPEPMTVTTGNP---FALECVVTGTPELSAKWFKDGRELSA 7614
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDV----LTVS---SDRASQEPPVFIK 189
+ +T + + A ++D G ++ + V TVS SDR PP FI+
Sbjct: 7615 DSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIV--PPSFIR 7672
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+L+DV A+ V SG ++ WF+D EI S + + E+ L + P
Sbjct: 7673 KLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEP 7732
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
SD G C A N G A L ++ P Q D + ++ + I G P
Sbjct: 7733 SDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPDSVEVLPGMSLTFTSVIRGTPP 7789
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
++W ++ + IS+ + L++ + + G+Y N G + +
Sbjct: 7790 FKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 7849
Query: 370 VTAP 373
V P
Sbjct: 7850 VKEP 7853
Score = 68.9 bits (161), Expect = 9e-11
Identities = 45/146 (30%), Positives = 65/146 (44%), Gaps = 4/146 (2%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P + + + A+T+ W P +DGG+ + GY +E G W R +V
Sbjct: 15503 PKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP 15562
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
GLE +YQFRV A N G S S + T + D P V ++ +V
Sbjct: 15563 ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPP-TKAVD-PIDAPKVILRTSLEVK- 15619
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDD 222
D++ + SG P PTI W KD+
Sbjct: 15620 -RGDEIALDASISGSPYPTITWIKDE 15644
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 2/192 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+ P FIK LE V + N KV T+ W KD ++ + I ++ + L
Sbjct: 4569 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G CTA+N G + A + + P + ++ + L E+ L
Sbjct: 4629 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS--FVKKVDPSYLMLPGESARLHC 4686
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G P + W + + + + + ++L I K D G Y +A N +G D
Sbjct: 4687 KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSD 4746
Query: 363 TAAFLVTVTAPP 374
+ + + + PP
Sbjct: 4747 SCSTEIVIKEPP 4758
Score = 66.5 bits (155), Expect = 5e-10
Identities = 61/228 (26%), Positives = 98/228 (42%), Gaps = 18/228 (7%)
Query: 152 QFRVAALNDVGHSNYSELSDV---LTVSSD--RASQEPPVFIKRLEDVTALENDKVEFHV 206
Q R A +ND G +D L SS + ++PPVF + L VT E + V+
Sbjct: 9235 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSC 9294
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G I W K EI S R + + T+VL + +D G+ C A+N G
Sbjct: 9295 HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSD 9354
Query: 267 VTKARLCLEAAPKL--RYPRQYEDGLLYEINE----TIFLKTT------IVGKPTPTIEW 314
TK+++ ++ P + + DG L+ ++E + KTT + G P P ++W
Sbjct: 9355 TTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 9414
Query: 315 -RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + R+ I + L+I ++D G Y+ A N GE
Sbjct: 9415 TKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 9462
Score = 66.1 bits (154), Expect = 6e-10
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 6/196 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP I+R E + D T +G P W+KD + +S++ I+ + +
Sbjct: 4941 KEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 5000
Query: 242 LLFHQILPSDEGEIKCTATNRGGHA---VTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
L F+ D G+ +N G + T L + AP P + D + +N T
Sbjct: 5001 LKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSV---VNGTC 5057
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
L I G + W DG I DR I+ + L+I +D G + +A N
Sbjct: 5058 RLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNS 5117
Query: 359 IGEDTAAFLVTVTAPP 374
+G ++ + V PP
Sbjct: 5118 VGSKDSSGALIVQEPP 5133
Score = 65.7 bits (153), Expect = 8e-10
Identities = 48/198 (24%), Positives = 90/198 (45%), Gaps = 6/198 (3%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP FI+ LE V A+ + G P I+W+K+ ++ S+ + + + L
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR--YPRQYEDGLLYE-INETIF 299
+ +++ SD GE C A N G + A L ++ KL + R+ +D ++E + +
Sbjct: 8005 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKER-KLPPFFARKLKD--VHETLGFPVA 8061
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ I G + W DG + D ++ S + L+I +S G+Y A N +
Sbjct: 8062 FECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPL 8121
Query: 360 GEDTAAFLVTVTAPPDPP 377
G +++ + ++ PP
Sbjct: 8122 GTASSSAKLILSEHEVPP 8139
Score = 65.3 bits (152), Expect = 1e-09
Identities = 59/242 (24%), Positives = 99/242 (40%), Gaps = 14/242 (5%)
Query: 147 PPHKYQFR--VAAL--NDVGHSNYSELS-----DVLTVSSD-----RASQEPPVFIKRLE 192
P +K QF+ VA+L N V HS+ E S V V+S + + PP F ++L+
Sbjct: 7991 PAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLK 8050
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV V F +G ++W+KD + + + + L Q S
Sbjct: 8051 DVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHI 8110
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C+A+N G A + A+L L + + + E+ K + G I
Sbjct: 8111 GQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKI 8170
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W D I ++++ + L + + D G+Y A NI G+D+ + + V
Sbjct: 8171 TWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQE 8230
Query: 373 PP 374
PP
Sbjct: 8231 PP 8232
Score = 64.9 bits (151), Expect = 1e-09
Identities = 65/286 (22%), Positives = 117/286 (40%), Gaps = 11/286 (3%)
Query: 116 QVECNRLGSTE----WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSEL 169
++EC GS E W R + + +T ++ Q + D G
Sbjct: 6369 RLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNP 6428
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
+ + S+ +EPPVF V L+N +V SG P + W+KD ++ SS+
Sbjct: 6429 AGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSK 6488
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ I + + + + SD GE C A N G + L+ P R+ + +
Sbjct: 6489 KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP--RFVSKL-NS 6545
Query: 290 LLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDR 348
L E L+ +I G ++W + +I + + I I+ + L+ A+ ++
Sbjct: 6546 LTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANA 6605
Query: 349 GEYQIQAKNIIG-EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
G+Y Q KN G E+ A L+ + + +T V ++ TL+
Sbjct: 6606 GKYICQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGETCTLE 6651
Score = 64.5 bits (150), Expect = 2e-09
Identities = 64/253 (25%), Positives = 99/253 (39%), Gaps = 11/253 (4%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H+ ++ ALND G + S LTV A PV +++E + +F
Sbjct: 4354 HQGEYVCEALNDSGKT---ATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEI 4406
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
P+ WFK EI+ S + +I + + S L + D GE C A+N G
Sbjct: 4407 QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 4466
Query: 269 KARLCL-EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
A L + EA P R L + + T+ G P W+ DG +
Sbjct: 4467 TATLTVTEAYPPTFLSR--PKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNW 4524
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPDPPRNVSVTRQV 386
+IS +L++ + DRG Y +A N G D A L+ + P V +
Sbjct: 4525 KISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAI 4584
Query: 387 DKSVTLDWEPPAD 399
+K V L+ + D
Sbjct: 4585 NKKVHLECQVDED 4597
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/228 (23%), Positives = 100/228 (43%), Gaps = 11/228 (4%)
Query: 168 ELSDVLTVSSDRAS---QEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWFKDDY 223
+LS+ + ++ +A+ +EPP FIK+ V L N + F +G P ++W+ D
Sbjct: 5768 QLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGN 5827
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
EI + ++ I+ + + + G C A N G A L ++ P +
Sbjct: 5828 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPT--FI 5885
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA 343
R+ + + + ++ + L+ + G P + W + I + + ++T + SV +H
Sbjct: 5886 RELKPVEVVKYSD-VELECEVTGTPPFEVTWLKNNREIRSSKKY--TLTDRVSVFNLHIT 5942
Query: 344 K--RSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKS 389
K SD GEYQ N G + + V + PP + + T V KS
Sbjct: 5943 KCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKS 5990
Score = 64.1 bits (149), Expect = 3e-09
Identities = 52/227 (22%), Positives = 91/227 (40%), Gaps = 7/227 (3%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A N +G ++ S +LT + PP F RL V A+ + +F +G
Sbjct: 9053 QYSCTATNPIGSAS-SSARLILT-----EGKNPPFFDIRLAPVDAVVGESADFECHVTGT 9106
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
++W KD EI S + I+ E+++ L ++ D G+ C A N G A+
Sbjct: 9107 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 9166
Query: 272 LCL-EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
L + E + ++ + + + L+ + G T+ W + I EI+
Sbjct: 9167 LNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEIT 9226
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPP 377
VL++ A +D G Y + N G + + P PP
Sbjct: 9227 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 9273
Score = 63.3 bits (147), Expect = 5e-09
Identities = 40/196 (20%), Positives = 80/196 (40%), Gaps = 6/196 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
QEP +++ + V E D + +G P + W KD +I SR +++ + + +
Sbjct: 6065 QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 6124
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL---EAAPKLRYPRQYEDGLLYEINETI 298
++ D G+ N G + A L + P D +L +I
Sbjct: 6125 FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL---GSSI 6181
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
++ + G + +W DG I T + + + L++++ + D Y + N+
Sbjct: 6182 HMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNV 6241
Query: 359 IGEDTAAFLVTVTAPP 374
G+D + ++TV PP
Sbjct: 6242 AGDDACSGILTVKEPP 6257
Score = 63.3 bits (147), Expect = 5e-09
Identities = 52/231 (22%), Positives = 97/231 (41%), Gaps = 10/231 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
W + + ++++ HK + + L+D+ +++ ++ + + + + P
Sbjct: 12533 WFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK-AQVKELSSTAQLKVLEADPY 12591
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F +L D TA+E D++ S + WFKD EI S + +I D +L +
Sbjct: 12592 FTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKK 12649
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
D+GE C G TKA + +EA +L + G+ + ET + +
Sbjct: 12650 ADLKDKGEYVCDC----GTDKTKANVTVEA--RLIKVEKPLYGVEVFVGETAHFEIEL-S 12702
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+P +W+ G P+ EI K +L +H+ + GE QA N
Sbjct: 12703 EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAAN 12753
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 3563 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 3620
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 3621 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3680
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCA 3706
Score = 62.5 bits (145), Expect = 8e-09
Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Query: 350 EYQIQAKNIIGEDTAAFL---VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
EY++ A+NI G + V P DPP VT KSV+L W P DGG K+
Sbjct: 26585 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKIT 26644
Query: 407 NYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPY-GMSAPSSESSP 463
YIVE WLK ++T + +L E Y+FR+ A + +S PS + P
Sbjct: 26645 GYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGP 26704
Query: 464 V 464
+
Sbjct: 26705 I 26705
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/248 (20%), Positives = 93/248 (37%), Gaps = 5/248 (2%)
Query: 153 FRVAALNDVGHSNYSELSDVLTVSSD-----RASQEPPVFIKRLEDVTALENDKVEFHVT 207
F +ND G + + T SS + Q PP F ++L+D+ V
Sbjct: 7065 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCR 7124
Query: 208 FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV 267
+G + W++D + + ++ + L Q S G+ C+A+N G A
Sbjct: 7125 LNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTAS 7184
Query: 268 TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
+ ARL K + + E+ + + G I W D I
Sbjct: 7185 SSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY 7244
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
I+ L+I + D G+Y QA N +G+D + ++V PP + + ++
Sbjct: 7245 TITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAK 7304
Query: 388 KSVTLDWE 395
+ ++ E
Sbjct: 7305 QGESIQLE 7312
Score = 59.7 bits (138), Expect = 6e-08
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 4/96 (4%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT 432
PP PP V + S++L W+PPA DGG + YIVE G W + K T
Sbjct: 16631 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 16690
Query: 433 ----LFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ +L E +Y+FR+KA + G S PS + +
Sbjct: 16691 CECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI 16726
Score = 59.3 bits (137), Expect = 7e-08
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 10/216 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F +L+D T +E D+V S +P + WFKD EI S+ I D +L+
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLIL 13003
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ L SD G+ C G T +L +E +++ R + E ET +T I
Sbjct: 13004 KKALKSDIGQYTCDC----GTDKTSGKLDIEDR-EIKLVRPLHSVEVME-TETARFETEI 13057
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
+ W+ G ++ EI K L +H+ + G QA N+
Sbjct: 13058 -SEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHL 13116
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
V P ++V+VT ++ T D E +D
Sbjct: 13117 RVKPRVIGLLRPLKDVTVT--AGETATFDCELSYED 13150
Score = 59.3 bits (137), Expect = 7e-08
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 11/125 (8%)
Query: 350 EYQIQAKNIIG-----EDTAAFLVT-VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
++Q++A+N G E T + T+PP PP ++ VT K + + W+PP +GG
Sbjct: 15182 QFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 15241
Query: 404 KVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEG----SEYKFRIKAESPYGMSAPSS 459
+ Y VE G W++ + SR F + EG EY R++A + G+S PS
Sbjct: 15242 PIIGYHVEMCPVGTEKWMR-VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSE 15300
Query: 460 ESSPV 464
S V
Sbjct: 15301 ISENV 15305
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/194 (21%), Positives = 78/194 (40%), Gaps = 4/194 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP V +++ +T + +G P ++ W+KD + SS++ + S L
Sbjct: 6629 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSL 6688
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFL 300
+ D G N G + A + + A P R G + + + L
Sbjct: 6689 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGV--LGASCIL 6746
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G ++ W H+ I++ + + + + L+++S SD G Y A N+ G
Sbjct: 6747 ECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 6806
Query: 361 EDTAAFLVTVTAPP 374
D ++TV PP
Sbjct: 6807 SDECRAVLTVQEPP 6820
Score = 58.8 bits (136), Expect = 1e-07
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 15/219 (6%)
Query: 159 NDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
ND G E S VLTV EP I++ E +T + +G P + W
Sbjct: 7555 NDAG---MRECSAVLTVL------EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKW 7605
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
FKD E+ + + IT + L SD+G N G + + + +
Sbjct: 7606 FKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKS--NCTVSVHVSD 7663
Query: 279 KLRYP---RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
++ P R+ +D + + ++ L+ + G ++ W DG+ I++ + + S +
Sbjct: 7664 RIVPPSFIRKLKD-VNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENV 7722
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
L + + SD G Y A N+ G D + ++TV PP
Sbjct: 7723 CTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 7761
Score = 58.8 bits (136), Expect = 1e-07
Identities = 71/327 (21%), Positives = 135/327 (41%), Gaps = 28/327 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE------PPVFIKRLEDVTALENDKVE 203
KY+ + + D G + E ++T D++ E P F++ LED T E D
Sbjct: 13712 KYK-HMLTIKDCGFPDEGEY--IVTAGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAV 13768
Query: 204 FHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG 263
F S + W+++ EI ++ D S L+ DE E C +R
Sbjct: 13769 FSCQLSR-EKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRK 13827
Query: 264 GHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
++ARL +E P + R +D L + +FL + K ++W + ++
Sbjct: 13828 ----SRARLFVEEIP-VEIIRPPQDILEAPGADVVFLAE--LNKDKVEVQWLRNNMVVVQ 13880
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
D+ ++ K L+I K D+GEY+ AK+ ++ A L AP + +
Sbjct: 13881 GDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKD---KEARAKLELAAAPKIKTADQDLV 13937
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI--TSRKTNVTLFDLIEGSE 441
V K +T+ P D E+++ + K I T+ +T+ + + +G +
Sbjct: 13938 VDVGKPLTM--VVPYD----AYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDK 13991
Query: 442 YKFRIKAESPYGMSAPSSESSPVRIPG 468
+++I ++ +G + + +PG
Sbjct: 13992 GRYKIVLQNKHGKAEGFINLKVIDVPG 14018
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/116 (32%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTN 430
P PP N V SV L W P DGGC++ YIVE W + KTN
Sbjct: 23765 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 23824
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR--AIDMDFLAVEARIIN 484
+ + L+E EY FRI A + G+ + P+ + + A D+D +IIN
Sbjct: 23825 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 23880
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/201 (23%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 3356 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 353 IQAKNIIGEDTAAFLVTVTAP 373
A N +G+ ++ +++ AP
Sbjct: 3416 FVASNAVGQVSSTANLSLEAP 3436
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKT 429
PP PP + + S+TL W P DGG V Y+VE + W T R T
Sbjct: 28093 PPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTT 28152
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR----IPGRAIDMDFLAVEARIINE 485
+ +L G Y FR+ A + G P + PV+ + ID+D +A+ +I +
Sbjct: 28153 EYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLD-VALRTSVIAK 28211
Query: 486 A 486
A
Sbjct: 28212 A 28212
Score = 56.8 bits (131), Expect = 4e-07
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P P++ + ++ +T+ W P +DGG + GY +E ST W+ +
Sbjct: 19322 KPGRPDPPEVTKVSKEE----MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAI 19377
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVG 162
+ + L P H+YQFRV A N++G
Sbjct: 19378 PERRMKVQNLLPDHEYQFRVKAENEIG 19404
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 9/95 (9%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW-NVWLKAITSRKT 429
PDPP VT+ + +T+ W PP DGG + Y +E + T W V AI R+
Sbjct: 19326 PDPPE---VTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRM 19382
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
V +L+ EY+FR+KAE+ G+ PS S PV
Sbjct: 19383 KVQ--NLLPDHEYQFRVKAENEIGIGEPSLPSRPV 19415
Score = 56.4 bits (130), Expect = 5e-07
Identities = 31/94 (32%), Positives = 48/94 (51%), Gaps = 4/94 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+ P +P++ + + NA++++W HDGG+ + GY VE + W++ L
Sbjct: 29768 PSAPTRPEVYHVSA----NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCL 29823
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
+TGL +YQFR ALN G S SE S
Sbjct: 29824 ECNYKVTGLVEGLEYQFRTYALNAAGVSKASEAS 29857
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/196 (26%), Positives = 81/196 (41%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF + EI S + + +
Sbjct: 2786 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVS 2844
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 2845 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 2896
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 2897 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 2953
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 2954 --VCGNDQVSATLTVT 2967
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA-ITTDEST 239
S E P +R++ T + F V G P P W+K+ +I S R +++
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ + D I A N G + A L ++A + + ++ +D + E +T+
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE-KDTMA 2192
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+P ++W DG + D+ + K L I + SD +Y
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2244
Score = 55.2 bits (127), Expect = 1e-06
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 9/165 (5%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ LED T E + F S + WFK+D ++ +SR I+++ T L +
Sbjct: 12503 FMSPLEDQTVKEGETATFVCELSH-EKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKE 12561
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +IK A K LEA P + + D E +E I LK V
Sbjct: 12562 VTLDDISQIKAQVKELSSTAQLKV---LEADPY--FTVKLHDKTAVEKDE-ITLKCE-VS 12614
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K P ++W DG I+ + I +LKI A D+GEY
Sbjct: 12615 KDVP-VKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEY 12658
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/117 (33%), Positives = 54/117 (46%), Gaps = 5/117 (4%)
Query: 351 YQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
Y + A + A+ + P D P VT +V+L W PA DGG KV YI+
Sbjct: 29843 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 29902
Query: 411 E---YYRTGWNVWLKA-ITSRKTN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
E G WLK T N T+ L EG Y+FR+ A++ G+ + SES+
Sbjct: 29903 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSEST 29959
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFH 245
F R+++ LE V FH SG P P IAW+KD I R + + + L
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+LP DEG A+N G+A+ +L +E A L P
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 54.4 bits (125), Expect = 2e-06
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTN 430
PP P V ++++ WE P DGG K+ Y VE +W+K + + N
Sbjct: 29767 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECN 29826
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG EY+FR A + G+S S S P+
Sbjct: 29827 YKVTGLVEGLEYQFRTYALNAAGVSKASEASRPI 29860
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 3024
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 3025 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 3077
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 3131
Score = 53.6 bits (123), Expect = 4e-06
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 7/178 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTS 240
P F+K ++D+ E++ V F + SP+ A W KD I S + D
Sbjct: 12041 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 12100
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + SD GE C + A+L +E P +R+ + E+ + + ++L
Sbjct: 12101 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP-VRFVKTLEEEVTVVKGQPLYL 12159
Query: 301 KTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ + WR DG ++ RI + L I+ A +D G Y + +N
Sbjct: 12160 SCEL--NKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN 12215
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 68/164 (41%), Gaps = 10/164 (6%)
Query: 338 LKIHSAKRSDRGEYQIQAKNI--IGEDTAAFLVTVTAPP----DPPRNVSVTRQVDKSVT 391
L++ E+++ A+N +GE + A + P PP N + S+T
Sbjct: 24805 LRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSIT 24864
Query: 392 LDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFD---LIEGSEYKFRIKA 448
L W P DGG ++ Y+VE + W VT F+ L E EYK R+ A
Sbjct: 24865 LAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCA 24924
Query: 449 ESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDG 492
+ G+ +S V+ P ++ L +++ + + R G
Sbjct: 24925 LNKVGLGEATSVPGTVK-PEDKLEAPELDLDSELRKGIVVRAGG 24967
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L++ P ++ V A N G S+ +S +LTV + Q P+F+++L++V E
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSS---ISVILTVEAVE-HQVKPMFVEKLKNVNIKEG 1570
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVLLFHQILPSDEGEIKC 257
++E V +G P+P I W K+ I + + I + + L + D
Sbjct: 1571 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1630
Query: 258 TATNRGGHAVTKARLCLE 275
TA N+ G T+ ++ +E
Sbjct: 1631 TAINKAGRDTTRCKVNVE 1648
Score = 52.0 bits (119), Expect = 1e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 8/101 (7%)
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY--------RTGWNVWLKAI 424
PP PP N V S+TL W P DGG + Y+VE GW A
Sbjct: 19423 PPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAA 19482
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ T+ L E EY+FR+ A++ G+ P+ ++
Sbjct: 19483 QLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIK 19523
Score = 50.8 bits (116), Expect = 3e-05
Identities = 44/189 (23%), Positives = 79/189 (41%), Gaps = 12/189 (6%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+E VF K L ++ E D ++ S P + W+K D EI + R I T+ +
Sbjct: 13387 EEEAVFTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRI 13445
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ D G C + K ++ AA + P+ E + E + F+
Sbjct: 13446 LVIQNAHLEDAGNYNCRLPS--SRTDGKVKVHELAAEFISKPQNLE---ILEGEKAEFVC 13500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + K + ++W+ D + + D+ ++ K VL + A D G Y + ++G
Sbjct: 13501 S--ISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVV----MVGA 13554
Query: 362 DTAAFLVTV 370
AA +TV
Sbjct: 13555 ARAAAHLTV 13563
Score = 49.6 bits (113), Expect = 6e-05
Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 3356 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3414
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPR 284
A+N G + A L LEA + + R
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHER 3443
Score = 48.0 bits (109), Expect = 2e-04
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 8/165 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F+ L+DVTA E + F V S + + WFK+D + ++R ++ + T + F
Sbjct: 12858 FLTPLKDVTAKEKESAVFTVELSH-DNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKD 12916
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ D +I+ A A LE P + + +D E +E I +
Sbjct: 12917 LSIDDTSQIRVEAMGMSSEAKLTV---LEGDP--YFTGKLQDYTGVEKDEVIL--QCEIS 12969
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
K ++W DG I I K +L + A +SD G+Y
Sbjct: 12970 KADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQY 13014
Score = 46.8 bits (106), Expect = 4e-04
Identities = 50/235 (21%), Positives = 92/235 (39%), Gaps = 13/235 (5%)
Query: 168 ELSDVLTVSSDRASQ-EPPVFIKRLEDVTALENDKVEFHVTFS-GIPSPTIAWFKDDYEI 225
E ++++ R SQ EP IK +E+ T L+++ F + P ++W+K ++
Sbjct: 9565 EFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKL 9624
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S + I+ D L D+G + G H + +E A + R
Sbjct: 9625 EPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC---GPHIASAKLTVIEPA----WERH 9677
Query: 286 YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
+D L E +T + T P EW +G + R + + K L I +
Sbjct: 9678 LQDVTLKE-GQTCTM-TCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRA 9735
Query: 346 SDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
D+G+Y + +++ E +A + R ++ +S T + E DD
Sbjct: 9736 EDQGQYTCKYEDL--ETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDD 9788
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 3598 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 3657
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 3658 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 3709
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K RP PP P + ++ ++ L W P DGGA + Y V+ W A
Sbjct: 22477 KVLDRPGPPEGPLAVTEVTSEK---CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVA 22533
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVS 176
+ + +L +T L ++Y FRV A+N G E VL V+
Sbjct: 22534 SEVQVT-KLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVN 22577
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/106 (27%), Positives = 43/106 (40%), Gaps = 4/106 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A +N K + GRP PP P +S D+ +TL W P DGG+ + Y
Sbjct: 17124 TAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ---MTLSWFPPKDDGGSKITNYV 17180
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+E W+ + + L H+Y FR+ A N G
Sbjct: 17181 IEKREANRKTWVHVSSE-PKECTYTIPKLLEGHEYVFRIMAQNKYG 17225
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 125 TEWIRTAPPIVLRPELVLTGLEPPHK-YQFRVAALNDVGHSNYS-ELSDVLTVSSDRASQ 182
+EW R +L+P+ E HK ++ +A + Y+ + D+ T + R
Sbjct: 9702 SEWFRNGR--ILKPQ-GRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEA 9758
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP F KR++++ E+ F S + W+K E+ S++ D +
Sbjct: 9759 EPIQFTKRIQNIVVSEHQSATFECEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYM 9817
Query: 243 LFHQILPSDEG 253
H + P DEG
Sbjct: 9818 TIHNVTPDDEG 9828
Score = 44.4 bits (100), Expect = 0.002
Identities = 42/186 (22%), Positives = 70/186 (37%), Gaps = 8/186 (4%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L+D E +V F+ + WF+++ IF S + I + L
Sbjct: 13573 LKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLD 13631
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D+ + TN G V A + LR +D E F V +
Sbjct: 13632 DQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCK--VNRLNV 13689
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVT 369
T++W +G + D+R+ + +L I D GEY + A G+D + A L+
Sbjct: 13690 TLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA----GQDKSVAELLI 13745
Query: 370 VTAPPD 375
+ AP +
Sbjct: 13746 IEAPTE 13751
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE---CNRLGSTEWIRTAPPIVL 136
PG+P++ +D + ++L W+ +DGG+ + GY +E + +G W++ IV
Sbjct: 29869 PGRPEV----TDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS 29924
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVG 162
+T L Y+FRV A N G
Sbjct: 29925 DNFFTVTALSEGDTYEFRVLAKNAAG 29950
Score = 44.0 bits (99), Expect = 0.003
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPS 213
+ DV + E S V+ T + P ++ L D E D V+ V S + S
Sbjct: 2325 VKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LES 2383
Query: 214 PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC 273
W KD E+ S R I D+ + +LL + D G T G T R+
Sbjct: 2384 VEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALG--LSTSGRVS 2441
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+ + + +D + E + + L+ + +++W + I DDR++ +
Sbjct: 2442 VYSVDVI---TPLKDVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497
Query: 334 KFSVLKIHSAKRSDRGEYQI 353
L I+ SD G Y++
Sbjct: 2498 TKQRLVINRTHASDEGPYKL 2517
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/176 (24%), Positives = 65/176 (36%), Gaps = 9/176 (5%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EPPV F K LED T E S + + WFK+ EI S++ I D
Sbjct: 13208 KEPPVEFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEILKSKKYEIVADGRVR 13266
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L+ H P D C A + T L + P + + R D + E F
Sbjct: 13267 KLVIHDCTPEDIKTYTCDAKD----FKTSCNLNV-VPPHVEFLRPLTDLQVREKEMARF- 13320
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
+ + ++W DG I + +I +L I+ D EY + +
Sbjct: 13321 -ECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVR 13375
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+A+++A +N+ +P PP P +S D + + W P + GG + Y
Sbjct: 25312 TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSAD---FVVISWEPPAYTGGCQISNYI 25368
Query: 117 VECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHS 164
VE +T W V R + +T L+ +YQFR+ A N G S
Sbjct: 25369 VEKRDTTTTTW-HMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 25415
Score = 43.6 bits (98), Expect = 0.004
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 6/146 (4%)
Query: 169 LSDVLTVSSDRASQEP--PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF 226
++D EP P FI + +E V F G P P + W K +
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 227 SSRRTAITTDESTS--VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ R ++ ++ T L+ D GE N+ G A L EA +L
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTP 310
Q E +LY+ T F++ VG+ P
Sbjct: 1184 QQE--MLYQTQVTAFVQEPKVGETAP 1207
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 175 VSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
V++D+ ++ P + E V LE + F +G P P + W+ + I S+R +
Sbjct: 1831 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1890
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
D L D GE+K TA N G K +L ++ R
Sbjct: 1891 YD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFR 1936
Score = 42.7 bits (96), Expect = 0.007
Identities = 38/127 (29%), Positives = 52/127 (40%), Gaps = 6/127 (4%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
VH P PP P I IL D P +T+ W P DGG+P+ Y VE W
Sbjct: 18523 VHLTVLDVPGPPTGP--INIL-DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTW- 18578
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ +L + L+ +Y FRV A N +G L TV+ + S P
Sbjct: 18579 GVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG--PPLDSTPTVAKHKFSPPSPPGK 18636
Query: 189 KRLEDVT 195
+ D+T
Sbjct: 18637 PVVTDIT 18643
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ +SD + +A +L W DGG+ + Y VE + +W+ TA V +
Sbjct: 19919 PGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWV-TALASVTKTS 19977
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHS 164
+ L P +Y FRV A N G S
Sbjct: 19978 CRVGKLIPGQEYIFRVRAENRFGIS 20002
Score = 42.7 bits (96), Expect = 0.007
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 53 GNHYSASHNAFKPRK-NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
GN+ + N R V+ K RP PP P +I ++ ++ TL W P DGG+
Sbjct: 23539 GNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEK---CTLAWKPPLQDGGSD 23595
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ Y VE W V +T L ++Y FR+ A+N G
Sbjct: 23596 IINYIVERRETSRLVW-TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYG 23645
Score = 42.3 bits (95), Expect = 0.009
Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 8/127 (6%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P P +I+ + SD T+ W P DGG ++ Y +E W T V
Sbjct: 19223 KPGPVRNLKIVDVSSD----RCTVCWDPPEDDGGCEIQNYILEKCETKRMVW-STYSATV 19277
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS-DRASQ-EPPVFIK-RLE 192
L P +T L ++Y FRV A N +G +E V+ + D+ + +PP K E
Sbjct: 19278 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKE 19337
Query: 193 DVTALEN 199
++T + N
Sbjct: 19338 EMTVVWN 19344
Score = 41.9 bits (94), Expect = 0.012
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-----PPDPPRNVSVTRQVDK 388
K+SV K+ K ++++A+N G + A PPD P V
Sbjct: 15788 KYSVTKLIEGKEY---LFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSN 15844
Query: 389 SVTLDWEPPADDGGCKVGNYIV--EYYRTGWNVWLKAITSR-KTNVTLFDLIEGSEYKFR 445
S+ + W P D+G +G ++ E T W+ K++ + K NV L+EG Y FR
Sbjct: 15845 SMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD--GLLEGLTYVFR 15902
Query: 446 IKAESPYGMSAPSSESSP 463
+ AE+ G S S P
Sbjct: 15903 VCAENAAGPGKFSPPSDP 15920
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L+DV A E D + + P + W+KD E+ + + +D L
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2235
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
I SD + C + T A+L +E A + + ++ +D E+ E+ + +
Sbjct: 2236 IDTSDAEDYSCVLV-EDENVKTTAKLIVEGA-VVEFVKELQD---IEVPESYSGELECIV 2290
Query: 307 KPTPTIE--WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
P IE W H+ + ++ + I+ L + + D+GEY
Sbjct: 2291 SP-ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 41.1 bits (92), Expect = 0.021
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 2529 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 2587
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 2588 KLTVLNMMKDDEGKY----TFYAGENITSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 2639
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 2640 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 2696
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 2697 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2756
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 2757 VKG-TIYSLRIKNCAIVDESVYGFRL 2781
Score = 40.3 bits (90), Expect = 0.036
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
GRP P P + +S + + L W GG + Y VE G+T W +
Sbjct: 29666 GRPGPVTGPIEVSSVSAE---SCVLSWGEPKDGGGTEITNYIVEKRESGTTAW-QLVNSS 29721
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
V R ++ +T L +Y FRV++ N G S E + ++
Sbjct: 29722 VKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPII 29760
Score = 39.9 bits (89), Expect = 0.048
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K RP PP P + ++ ++ L W P DGGA + Y +E W + +
Sbjct: 25724 KVLDRPGPPEGPLKVTGVTAEK---CYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVS 25780
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
V +T L P ++Y FRV A+N G
Sbjct: 25781 TE-VQALNYKVTKLLPGNEYIFRVMAVNKYG 25810
Score = 39.9 bits (89), Expect = 0.048
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
Query: 79 PPGKPQIIPILSDD-EPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
PP KP+ PI D+ + +++ L W +GG + Y +E T W + V R
Sbjct: 28583 PPSKPKG-PIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNW-KMVCSSVAR 28640
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHS 164
+ L +YQFRV A N G S
Sbjct: 28641 TTFKVPNLVKDAEYQFRVRAENRYGVS 28667
Score = 39.1 bits (87), Expect = 0.084
Identities = 42/236 (17%), Positives = 86/236 (36%), Gaps = 9/236 (3%)
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+W P+ P+ + H L G ++ + ++ + ++ + + P
Sbjct: 12709 QWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSF-QAANAKSAANLKVKELPL 12767
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
+FI L DV E D+ +F S P T W K EI R + D + ++
Sbjct: 12768 IFITPLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIK 12826
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
DE + A ++ H T +L +E +L++ +D E +F T +
Sbjct: 12827 SAAFEDEAKYMFEAEDK--H--TSGKLIIEGI-RLKFLTPLKDVTAKEKESAVF--TVEL 12879
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
++W + + T + + K + D + +++A + E
Sbjct: 12880 SHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSE 12935
Score = 39.1 bits (87), Expect = 0.084
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +D + L W P DGG+ + Y VE S W + + V
Sbjct: 14711 PGPPAAFDI-TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTN 14768
Query: 140 LVLTGLEPPHKYQFRVAALNDVG 162
T L P +Y FRVAA N G
Sbjct: 14769 FKATKLIPNKEYIFRVAAENMYG 14791
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/170 (21%), Positives = 65/170 (38%), Gaps = 8/170 (4%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
++ L+DVT + F S P + W+ ++ S + ++ L +
Sbjct: 13126 LRPLKDVTVTAGETATFDCELSYEDIP-VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDV 13184
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
D GE++ TA + HA + P + + + ED + E T L+ V +
Sbjct: 13185 KLEDAGEVQLTAKDFKTHANLFVK-----EPPVEFTKPLEDQTVEE-GATAVLECE-VSR 13237
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++W +G I+ + EI + L IH D Y AK+
Sbjct: 13238 ENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD 13287
Score = 38.3 bits (85), Expect = 0.15
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 2/114 (1%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT--IAWFKDDYEIFSSRRTAITT 235
D+ Q+ P F K+L + F + I PT + W D + ++ R +
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN 1755
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ L + D G I C ATN+ G T A L ++ L Q +G
Sbjct: 1756 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEG 1809
Score = 37.9 bits (84), Expect = 0.19
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPH-KYQFRV 155
++L W DGG+ + GY VE + W+ A E +TGL+ +Y FRV
Sbjct: 14033 VSLAWEEPLTDGGSKIIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRV 14091
Query: 156 AALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
+A N VG E + + S PP+
Sbjct: 14092 SARNRVGTGEPVETDNPVEARSKYDVPGPPL 14122
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ T +G PT +EW HDG P+ +R+ + + L A D G +A N G
Sbjct: 1725 RLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1784
Query: 361 ED-TAAFLV 368
D T+A L+
Sbjct: 1785 TDHTSATLI 1793
Score = 36.3 bits (80), Expect = 0.59
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK--IHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P+ T R ++S + K I D GEY I +N GE +
Sbjct: 1107 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1166
Query: 364 AA 365
A+
Sbjct: 1167 AS 1168
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E++ L+ I G P+PT+ W + + I + +I+ + L I A D G + A
Sbjct: 958 ESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 1017
Query: 356 KNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQ 385
N G T+ +L + +VT +
Sbjct: 1018 VNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Score = 35.5 bits (78), Expect = 1.0
Identities = 32/131 (24%), Positives = 55/131 (41%), Gaps = 8/131 (6%)
Query: 57 SASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQ 116
+AS+ +NVH + RP+PP + +D + + L W +GG+ + Y
Sbjct: 16405 TASNRLGSVFRNVHVEVYDRPSPPRNLAV----TDIKAESCYLTWDAPLDNGGSEITHYV 16460
Query: 117 VECNRLG--STEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
++ EW V + + L P +Y+FRV A+N G S+ + SD +
Sbjct: 16461 IDKRDASRKKAEWEEVTNTAVEK-RYGIWKLIPNGQYEFRVRAVNKYGISDECK-SDKVV 16518
Query: 175 VSSDRASQEPP 185
+ PP
Sbjct: 16519 IQDPYRLPGPP 16529
Score = 33.9 bits (74), Expect = 3.2
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 69 VHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
V+ K +P PP P I L+ ++ +L W DGGA + Y VE W
Sbjct: 26802 VNCKVLDKPGPPAGPLEINGLTAEK---CSLSWGRPQEDGGADIDYYIVEKRETSHLAWT 26858
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ + +T L ++Y FRV +N G
Sbjct: 26859 ICEGELQM-TSCKVTKLLKGNEYIFRVTGVNKYG 26891
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 3522 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 3581
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 3582 GKTICSAYLKINSKGEGHKDTETESAVAKSL 3612
Score = 33.1 bits (72), Expect = 5.5
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 8/102 (7%)
Query: 758 EKDEFSESQTLKPLPDPNFVPKPILKRREIPEQSPAQNLMPPKSFVSAPKTEAKRQ-EKL 816
E ++ E LKP P P P P + ++ E+ +P K P+ K + L
Sbjct: 11794 EPEKVIEKPKLKPRPPP---PPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPL 11850
Query: 817 TL---FKKITKM-PVQKPFNFPKILSKNSMNKKQNTSEPEIE 854
+ KK+ K+ P +KP +++ K+ + K+ EP++E
Sbjct: 11851 KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 11892
Score = 32.7 bits (71), Expect = 7.3
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 4/85 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVE--CNRLGSTEWIRTAPPIVLR 137
PG P I + D ++ KW P DGG+ + Y +E +EWI +
Sbjct: 15729 PGPP-INFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWI-VVTSTLRH 15786
Query: 138 PELVLTGLEPPHKYQFRVAALNDVG 162
+ +T L +Y FRV A N G
Sbjct: 15787 CKYSVTKLIEGKEYLFRVRAENRFG 15811
>X64698-1|CAA45939.1| 1100|Homo sapiens titin protein.
Length = 1100
Score = 138 bits (334), Expect = 1e-31
Identities = 116/406 (28%), Positives = 174/406 (42%), Gaps = 26/406 (6%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P P P I+ + D +++L W GG+P+ GY +E S W R +
Sbjct: 83 PDAPPPPNIVDVRHD----SVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIR 138
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKRLEDVT 195
+ +TGL +Y+FRV A+N G S S+ V+ + +P V VT
Sbjct: 139 MRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVT 198
Query: 196 ALEND-KVEFHVTFSGI-----PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+ + K + +G P+ +W K ++ +T F
Sbjct: 199 LIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAK 258
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEA--APKLRYPRQYEDGLLYEINETIFLKT-TIVG 306
+ G I + + T+ +C + AP + +DGL + +TI L +I+G
Sbjct: 259 NTAGAISAPSES------TETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILG 312
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
KP P W G I D +I+ TP S+L I A R D GEY I A N G
Sbjct: 313 KPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHV 372
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKA 423
VTV P PP V ++ + TL W PP +DGG + +YI+E T W V +
Sbjct: 373 KVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED 432
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I S + T LI+G+EY FR+ A + YG P +S PV++ R
Sbjct: 433 IQSCRHVAT--KLIQGNEYIFRVSAVNHYGKGEP-VQSEPVKMVDR 475
Score = 126 bits (304), Expect = 4e-28
Identities = 115/423 (27%), Positives = 173/423 (40%), Gaps = 23/423 (5%)
Query: 54 NHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR 113
NHY +P ++ K R PPG P+ P +S+ N T+ W DGG+ +
Sbjct: 457 NHYGKG----EPVQSEPVKMVDRFGPPGPPEK-PEVSNVTKNTATVSWKRPVDDGGSEIT 511
Query: 114 GYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL 173
GY VE S W+R V +TGL+ Y+FRV+A N G SE SD +
Sbjct: 512 GYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSV 571
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
+ D A P + D T G T + + ++
Sbjct: 572 LMK-DAAYPPGPPSNPHVTDTTKKSASLAWGKPHIDGGLEIT-GYVVEHQKVGDEAWIKD 629
Query: 234 TTDESTSVLLF--HQILPSDEGEIKCTATNRGG----HAVTKARLC-LEAAPKLRYPRQY 286
TT + + F + ++ + +A N G + + E AP +
Sbjct: 630 TTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAEL 689
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS 346
L+ +I + I G+P P + W D I +R I T F++L I R
Sbjct: 690 RRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDN--INLKNRANIENTESFTLLIIPECNRY 747
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTV--TAPPDPP-RNVSVTRQVDKSVTLDWEPPADDGGC 403
D G++ + +N G+ + V V TA P P R +T+ SVTL W+ P DGG
Sbjct: 748 DTGKFVMTIENPAGKKSGFVNVRVLDTARPSPQLRPTDITKD---SVTLHWDLPLIDGGS 804
Query: 404 KVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
++ NYIVE + A T K + L EG EY FR+ AE+ YG+ P+ +
Sbjct: 805 RITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 864
Query: 463 PVR 465
PV+
Sbjct: 865 PVK 867
Score = 122 bits (293), Expect = 9e-27
Identities = 115/428 (26%), Positives = 182/428 (42%), Gaps = 47/428 (10%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR- 137
PPG P P ++D + +L W DGG + GY VE ++G WI+ LR
Sbjct: 579 PPGPPSN-PHVTDTTKKSASLAWGKPHIDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI 637
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ-EPPVFIKRLEDVTA 196
+ V+ L+ KY FR++A+ND G + + DV V + A E ++R V A
Sbjct: 638 TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRA 697
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V G P+P + W KD+ + R I ES ++L+ + D G+
Sbjct: 698 --GLSIRIFVPIKGRPAPEVTWTKDNINL--KNRANIENTESFTLLIIPECNRYDTGKFV 753
Query: 257 CTATNRGGH--AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
T N G R+ A P P+ L+ T + K + T+ W
Sbjct: 754 MTIENPAGKKSGFVNVRVLDTARPS---PQ---------------LRPTDITKDSVTLHW 795
Query: 315 RH---DGHPIITDDRIEISITPKFS----VLKIHSAKRSDRG-----EY--QIQAKNI-- 358
DG IT+ +E + S K H G EY ++ A+N
Sbjct: 796 DLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYG 855
Query: 359 IGEDTAAFL-VTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW 417
IGE T V + P PP ++++ +V+L W P DGG K+ Y++E R G
Sbjct: 856 IGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGS 915
Query: 418 NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI--DMDF 475
+ W T + + +L EG EY F++ A + G SAP ES PV + + + ++D
Sbjct: 916 DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RESRPVIVKEQTMLPELDL 974
Query: 476 LAVEARII 483
+ +++
Sbjct: 975 RGIYQKLV 982
Score = 93.5 bits (222), Expect = 4e-18
Identities = 84/346 (24%), Positives = 144/346 (41%), Gaps = 19/346 (5%)
Query: 68 NVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW 127
NV RP+P +P +D +++TL W DGG+ + Y VE R + +
Sbjct: 768 NVRVLDTARPSPQLRP------TDITKDSVTLHWDLPLIDGGSRITNYIVE-KREATRKS 820
Query: 128 IRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF 187
TA + +TGL +Y FRV A N+ G +E ++ + S + PP
Sbjct: 821 YSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASE---APSPPDS 877
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ + D+T G S + + S + T ITT + ++ +
Sbjct: 878 LN-IMDITKSTVSLAWPKPKHDG-GSKITGYVIEAQRKGSDQWTHITTVKGLECVV-RNL 934
Query: 248 LPSDEGEIKCTATNRGGHAVTKAR---LCLEAA--PKLRYPRQYEDGLLYEINETIFLKT 302
+E + A N G + + + E P+L Y+ ++ + + I ++
Sbjct: 935 TEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEI 994
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
++G+P PT+ W+ + R+ T ++L I+ RSD G Y + A+NI+GE
Sbjct: 995 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEV 1054
Query: 363 TAAFLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGN 407
+ V P PP +V VT W+PP +DGG + N
Sbjct: 1055 GDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISN 1100
Score = 59.7 bits (138), Expect = 6e-08
Identities = 30/75 (40%), Positives = 44/75 (58%), Gaps = 2/75 (2%)
Query: 391 TLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAE 449
TL W PP DDGG ++ NYI+E + N W+ ++ +KT + L EG EY FR+ AE
Sbjct: 1 TLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAE 60
Query: 450 SPYGMSAPSSESSPV 464
+ YG+ +S P+
Sbjct: 61 NKYGV-GEGLKSEPI 74
Score = 42.3 bits (95), Expect = 0.009
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 98 TLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAA 157
TLKWAP DGG+ + Y +E + +W+ T V + +T L +Y FRV+A
Sbjct: 1 TLKWAPPKDDGGSEITNYILEKRDSVNNKWV-TCASAVQKTTFRVTRLHEGMEYTFRVSA 59
Query: 158 LNDVG 162
N G
Sbjct: 60 ENKYG 64
>BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein C,
fast type protein.
Length = 1141
Score = 123 bits (296), Expect = 4e-27
Identities = 102/396 (25%), Positives = 169/396 (42%), Gaps = 16/396 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P+ + I S E AI L W P +DGG P+ GY VE + GS W++ +
Sbjct: 639 PDPPEAVRITSVGEDWAI-LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 697
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
T + Y+ RV A+N +G S S ++ + S+ + ++ + D T
Sbjct: 698 YESTKMIEGILYEMRVFAVNAIGVSQPS-MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 756
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCT 258
+ + GI + + + E + T +V + LP+ + +
Sbjct: 757 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV----KNLPTGARILFRVV 812
Query: 259 ATNRGGHA--VTKARLC----LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
N G + T A+ + PK+R PR + ++ E + L GKP P +
Sbjct: 813 GVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQV 872
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W G P+ T R+ + + +V + A RSD GEY++ + +DTA + V
Sbjct: 873 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 931
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI-TSRKTNV 431
PP NV V + ++W+ P DDG ++ Y V+ W +R T+
Sbjct: 932 KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSC 991
Query: 432 TLFDLIEGSEYKFRIKAESPYGMS-APSSESSPVRI 466
T+ DLI G+EY FR+ E+ G+S +P + RI
Sbjct: 992 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1027
Score = 108 bits (260), Expect = 9e-23
Identities = 81/290 (27%), Positives = 123/290 (42%), Gaps = 15/290 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
++ + D+T +++ F S T W+K+ E+ S+R I+ L+ +
Sbjct: 442 LQDIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLC---LEAAPKLRYPRQY--------EDGLLYEINE 296
P DEG+ K +E PK P+ + E+ ++
Sbjct: 501 RPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGN 560
Query: 297 TIFLKTTIVGKPTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L +I G+P P W + D T+ R I S I SA+R D G Y I+
Sbjct: 561 KLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKV 620
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N +GED A+ + V PDPP V +T + L WEPP DGG V Y+VE +
Sbjct: 621 TNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKK 680
Query: 416 GWNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
G W+K T T +IEG Y+ R+ A + G+S PS + P
Sbjct: 681 GSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 730
Score = 67.7 bits (158), Expect = 2e-10
Identities = 59/208 (28%), Positives = 87/208 (41%), Gaps = 10/208 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
AP +P + I+ D TLKW P G + GY VE GS EW+ V R
Sbjct: 735 APTSEPLHL-IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 793
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP-VFIKRLEDVTA 196
+ L + FRV +N G S + L+ +T+ R EPP + + R T
Sbjct: 794 CGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTI---REIAEPPKIRLPRHLRQTY 850
Query: 197 LE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ +++ V F G P P + W K + +SR T+D T V Q SD GE
Sbjct: 851 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGE 909
Query: 255 IKCTA--TNRGGHAVTKARLCLEAAPKL 280
+ + N A + R+ +A P +
Sbjct: 910 YELSVQIENMKDTATIRIRVVEKAGPPI 937
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/190 (22%), Positives = 71/190 (37%), Gaps = 14/190 (7%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
NA+ ++W DG + + GY V+ + EW ++ L ++Y FR
Sbjct: 948 NAL-VEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFR 1005
Query: 155 VAALNDVGHSNYSELS-DVLTVSSDRASQEP-----------PVFIKRLEDVTALENDKV 202
V N G S+ +S + + + +P P F+ L D +
Sbjct: 1006 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1065
Query: 203 EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNR 262
+ G P P + W K+ EI + IT + L + P D G C A N
Sbjct: 1066 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNE 1125
Query: 263 GGHAVTKARL 272
G A+ + +L
Sbjct: 1126 LGEALAECKL 1135
>X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein.
Length = 1142
Score = 122 bits (295), Expect = 5e-27
Identities = 102/396 (25%), Positives = 168/396 (42%), Gaps = 16/396 (4%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P+ + I S E AI L W P +DGG P+ GY VE + GS W++ +
Sbjct: 640 PDPPEAVRITSVGEDWAI-LVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETT 698
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
T + Y+ RV A+N +G S S ++ + S+ + ++ + D T
Sbjct: 699 YESTKMIEGILYEMRVFAVNAIGVSQPS-MNTKPFMPIAPTSEPLHLIVEDVTDTTTTLK 757
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCT 258
+ + GI + + + E + T +V + LP+ + +
Sbjct: 758 WRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTV----KNLPTGARILFRVV 813
Query: 259 ATNRGGHA--VTKARLC----LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
N G T A+ + PK+R PR + ++ E + L GKP P +
Sbjct: 814 GVNIAGRTEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQV 873
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W G P+ T R+ + + +V + A RSD GEY++ + +DTA + V
Sbjct: 874 VWTKGGAPLDTS-RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVE 932
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAI-TSRKTNV 431
PP NV V + ++W+ P DDG ++ Y V+ W +R T+
Sbjct: 933 KAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSC 992
Query: 432 TLFDLIEGSEYKFRIKAESPYGMS-APSSESSPVRI 466
T+ DLI G+EY FR+ E+ G+S +P + RI
Sbjct: 993 TVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARI 1028
Score = 108 bits (259), Expect = 1e-22
Identities = 82/291 (28%), Positives = 124/291 (42%), Gaps = 16/291 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
++ + D+T +++ F S T W+K+ E+ S+R I+ L+ +
Sbjct: 442 LQDIADLTVKASEQAVFKCEVSD-EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDV 500
Query: 248 LPSDEGEIKCTATNRG-GHAVTKARLC---LEAAPKLRYPRQY--------EDGLLYEIN 295
P DEG+ G K +E PK P+ + E+ ++
Sbjct: 501 RPEDEGDYTFVPDGYALGSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAG 560
Query: 296 ETIFLKTTIVGKPTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
+ L +I G+P P W + D T+ R I S I SA+R D G Y I+
Sbjct: 561 NKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIK 620
Query: 355 AKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
N +GED A+ + V PDPP V +T + L WEPP DGG V Y+VE +
Sbjct: 621 VTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKK 680
Query: 415 TGWNVWLKAITSRKTNVTL--FDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
G W+K T T +IEG Y+ R+ A + G+S PS + P
Sbjct: 681 KGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKP 731
Score = 66.5 bits (155), Expect = 5e-10
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 10/208 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
AP +P + I+ D TLKW P G + GY VE GS EW+ V R
Sbjct: 736 APTSEPLHL-IVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVER 794
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP-VFIKRLEDVTA 196
+ L + FRV +N G + + L+ +T+ R EPP + + R T
Sbjct: 795 CGFTVKNLPTGARILFRVVGVNIAGRTEPATLAQPVTI---REIAEPPKIRLPRHLRQTY 851
Query: 197 LE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ +++ V F G P P + W K + +SR T+D T V Q SD GE
Sbjct: 852 IRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDT-VFFVRQAARSDSGE 910
Query: 255 IKCTA--TNRGGHAVTKARLCLEAAPKL 280
+ + N A + R+ +A P +
Sbjct: 911 YELSVQIENMKDTATIRIRVVEKAGPPI 938
Score = 44.0 bits (99), Expect = 0.003
Identities = 43/190 (22%), Positives = 71/190 (37%), Gaps = 14/190 (7%)
Query: 95 NAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFR 154
NA+ ++W DG + + GY V+ + EW ++ L ++Y FR
Sbjct: 949 NAL-VEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERN-RHTSCTVSDLIVGNEYYFR 1006
Query: 155 VAALNDVGHSNYSELS-DVLTVSSDRASQEP-----------PVFIKRLEDVTALENDKV 202
V N G S+ +S + + + +P P F+ L D +
Sbjct: 1007 VYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSA 1066
Query: 203 EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNR 262
+ G P P + W K+ EI + IT + L + P D G C A N
Sbjct: 1067 ALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNE 1126
Query: 263 GGHAVTKARL 272
G A+ + +L
Sbjct: 1127 LGEALAECKL 1136
>X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein.
Length = 1123
Score = 122 bits (293), Expect = 9e-27
Identities = 103/416 (24%), Positives = 180/416 (43%), Gaps = 32/416 (7%)
Query: 55 HYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRG 114
H + + A + ++ K P PP P + + DD + W P +DGG+P+ G
Sbjct: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV-GDDW---CIMNWEPPAYDGGSPILG 653
Query: 115 YQVECNRLGSTEWIRT----APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
Y +E + S+ W+R P+ ++ G+ Y+ R+ A+N +G S S S
Sbjct: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Query: 171 DVLTVSSDRASQEPPVF--IKRLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFS 227
A PP + + D T + H+ +G+ + + F+ +
Sbjct: 710 RPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 766
Query: 228 SRRTAITTDESTSVLLFHQILPSDEGE-IKCTATNRGGHAVTKAR----LCLEAA--PKL 280
+ + I + T L P+D ++ A N G + K L E PK+
Sbjct: 767 ANKDLIDKTKFTITGL-----PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 821
Query: 281 RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKI 340
R PR + + + E + L GKP P + W+ DG I ++I I + +++ I
Sbjct: 822 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFI 880
Query: 341 HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
A+RS G+Y +Q K +TA+ + + P PP+ V + ++V L W PP DD
Sbjct: 881 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 940
Query: 401 GGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
G + Y ++ W I +T+ T+ +L+ G+EY FR+ +E+ G+S
Sbjct: 941 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 996
Score = 90.6 bits (215), Expect = 3e-17
Identities = 72/250 (28%), Positives = 104/250 (41%), Gaps = 6/250 (2%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W K+ + S R + L+ L DEG+ + A++ +
Sbjct: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
Query: 278 PKLRYPRQYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKF 335
PK+ D + I + L+ I G+P P W I+ RI P
Sbjct: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
S L I A+R D G Y I KN GE A+ V V PDPP +VT D ++WE
Sbjct: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWE 641
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PPA DGG + Y +E + + W++ ++T +IEG Y+ RI A + G
Sbjct: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
Query: 454 MSAPSSESSP 463
+S PS S P
Sbjct: 702 ISKPSMPSRP 711
Score = 62.9 bits (146), Expect = 6e-09
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQI+ I D + L W P DG A + GY ++ S EW T R
Sbjct: 914 PGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTS 971
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL---SDVLT---------VSSDRASQEPPVF 187
+T L ++Y FRV + N G S + + S V+ V D E P+F
Sbjct: 972 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1031
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + A+ + + G P P I W K+ I R + +++ L +
Sbjct: 1032 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1091
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G + +L
Sbjct: 1092 SPYDGGTYCCKAVNDLGTVEIECKL 1116
Score = 50.0 bits (114), Expect = 4e-05
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 23/223 (10%)
Query: 176 SSDRASQEPPVFI-KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS--RRTA 232
S++ +EPP+ + K+LED TA ++VE S + WFK+ EI R
Sbjct: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYR 390
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
I + +L+ +D E T GG + A+L ++ P L+ D +
Sbjct: 391 IRVEGKKHILIIEGATKADAAEYSVMTT--GGQS--SAKLSVDLKP-LKILTPLTDQTV- 444
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ + I LK I + P +W +G P+ DR+++ + L I +A D G+Y
Sbjct: 445 NLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 501
Query: 353 IQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQVDKSVTL 392
+ D A+ VT+ A DPP+ + D +VT+
Sbjct: 502 -----VFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTV 537
Score = 49.6 bits (113), Expect = 6e-05
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
A PP ++V D +VT+ W PP G + Y++EY G W+ A KT
Sbjct: 716 AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 775
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ L ++ R+KA + G S P S P+ +
Sbjct: 776 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 812
>BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein.
Length = 1120
Score = 122 bits (293), Expect = 9e-27
Identities = 103/416 (24%), Positives = 180/416 (43%), Gaps = 32/416 (7%)
Query: 55 HYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRG 114
H + + A + ++ K P PP P + + DD + W P +DGG+P+ G
Sbjct: 572 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV-GDDW---CIMNWEPPAYDGGSPILG 627
Query: 115 YQVECNRLGSTEWIRT----APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
Y +E + S+ W+R P+ ++ G+ Y+ R+ A+N +G S S S
Sbjct: 628 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 683
Query: 171 DVLTVSSDRASQEPPVF--IKRLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFS 227
A PP + + D T + H+ +G+ + + F+ +
Sbjct: 684 RPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 740
Query: 228 SRRTAITTDESTSVLLFHQILPSDEGE-IKCTATNRGGHAVTKAR----LCLEAA--PKL 280
+ + I + T L P+D ++ A N G + K L E PK+
Sbjct: 741 ANKDLIDKTKFTITGL-----PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 795
Query: 281 RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKI 340
R PR + + + E + L GKP P + W+ DG I ++I I + +++ I
Sbjct: 796 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFI 854
Query: 341 HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
A+RS G+Y +Q K +TA+ + + P PP+ V + ++V L W PP DD
Sbjct: 855 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 914
Query: 401 GGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
G + Y ++ W I +T+ T+ +L+ G+EY FR+ +E+ G+S
Sbjct: 915 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 970
Score = 90.6 bits (215), Expect = 3e-17
Identities = 72/250 (28%), Positives = 104/250 (41%), Gaps = 6/250 (2%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W K+ + S R + L+ L DEG+ + A++ +
Sbjct: 438 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 495
Query: 278 PKLRYPRQYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKF 335
PK+ D + I + L+ I G+P P W I+ RI P
Sbjct: 496 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 555
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
S L I A+R D G Y I KN GE A+ V V PDPP +VT D ++WE
Sbjct: 556 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWE 615
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PPA DGG + Y +E + + W++ ++T +IEG Y+ RI A + G
Sbjct: 616 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 675
Query: 454 MSAPSSESSP 463
+S PS S P
Sbjct: 676 ISKPSMPSRP 685
Score = 62.9 bits (146), Expect = 6e-09
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQI+ I D + L W P DG A + GY ++ S EW T R
Sbjct: 888 PGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTS 945
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL---SDVLT---------VSSDRASQEPPVF 187
+T L ++Y FRV + N G S + + S V+ V D E P+F
Sbjct: 946 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1005
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + A+ + + G P P I W K+ I R + +++ L +
Sbjct: 1006 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1065
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G + +L
Sbjct: 1066 SPYDGGTYCCKAVNDLGTVEIECKL 1090
Score = 50.0 bits (114), Expect = 4e-05
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 23/223 (10%)
Query: 176 SSDRASQEPPVFI-KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS--RRTA 232
S++ +EPP+ + K+LED TA ++VE S + WFK+ EI R
Sbjct: 306 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYR 364
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
I + +L+ +D E T GG + A+L ++ P L+ D +
Sbjct: 365 IRVEGKKHILIIEGATKADAAEYSVMTT--GGQS--SAKLSVDLKP-LKILTPLTDQTV- 418
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ + I LK I + P +W +G P+ DR+++ + L I +A D G+Y
Sbjct: 419 NLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 475
Query: 353 IQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQVDKSVTL 392
+ D A+ VT+ A DPP+ + D +VT+
Sbjct: 476 -----VFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTV 511
Score = 49.6 bits (113), Expect = 6e-05
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
A PP ++V D +VT+ W PP G + Y++EY G W+ A KT
Sbjct: 690 AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 749
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ L ++ R+KA + G S P S P+ +
Sbjct: 750 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 786
>BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein C,
slow type protein.
Length = 1123
Score = 122 bits (293), Expect = 9e-27
Identities = 103/416 (24%), Positives = 180/416 (43%), Gaps = 32/416 (7%)
Query: 55 HYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRG 114
H + + A + ++ K P PP P + + DD + W P +DGG+P+ G
Sbjct: 598 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV-GDDW---CIMNWEPPAYDGGSPILG 653
Query: 115 YQVECNRLGSTEWIRT----APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
Y +E + S+ W+R P+ ++ G+ Y+ R+ A+N +G S S S
Sbjct: 654 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 709
Query: 171 DVLTVSSDRASQEPPVF--IKRLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFS 227
A PP + + D T + H+ +G+ + + F+ +
Sbjct: 710 RPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 766
Query: 228 SRRTAITTDESTSVLLFHQILPSDEGE-IKCTATNRGGHAVTKAR----LCLEAA--PKL 280
+ + I + T L P+D ++ A N G + K L E PK+
Sbjct: 767 ANKDLIDKTKFTITGL-----PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 821
Query: 281 RYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKI 340
R PR + + + E + L GKP P + W+ DG I ++I I + +++ I
Sbjct: 822 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFI 880
Query: 341 HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
A+RS G+Y +Q K +TA+ + + P PP+ V + ++V L W PP DD
Sbjct: 881 RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 940
Query: 401 GGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
G + Y ++ W I +T+ T+ +L+ G+EY FR+ +E+ G+S
Sbjct: 941 GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 996
Score = 90.6 bits (215), Expect = 3e-17
Identities = 72/250 (28%), Positives = 104/250 (41%), Gaps = 6/250 (2%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W K+ + S R + L+ L DEG+ + A++ +
Sbjct: 464 WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 521
Query: 278 PKLRYPRQYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKF 335
PK+ D + I + L+ I G+P P W I+ RI P
Sbjct: 522 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 581
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
S L I A+R D G Y I KN GE A+ V V PDPP +VT D ++WE
Sbjct: 582 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWE 641
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PPA DGG + Y +E + + W++ ++T +IEG Y+ RI A + G
Sbjct: 642 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 701
Query: 454 MSAPSSESSP 463
+S PS S P
Sbjct: 702 ISKPSMPSRP 711
Score = 62.9 bits (146), Expect = 6e-09
Identities = 55/205 (26%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQI+ I D + L W P DG A + GY ++ S EW T R
Sbjct: 914 PGPPQIVKI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTS 971
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL---SDVLT---------VSSDRASQEPPVF 187
+T L ++Y FRV + N G S + + S V+ V D E P+F
Sbjct: 972 ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1031
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + A+ + + G P P I W K+ I R + +++ L +
Sbjct: 1032 TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1091
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G + +L
Sbjct: 1092 SPYDGGTYCCKAVNDLGTVEIECKL 1116
Score = 50.0 bits (114), Expect = 4e-05
Identities = 58/223 (26%), Positives = 97/223 (43%), Gaps = 23/223 (10%)
Query: 176 SSDRASQEPPVFI-KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS--RRTA 232
S++ +EPP+ + K+LED TA ++VE S + WFK+ EI R
Sbjct: 332 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYR 390
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
I + +L+ +D E T GG + A+L ++ P L+ D +
Sbjct: 391 IRVEGKKHILIIEGATKADAAEYSVMTT--GGQS--SAKLSVDLKP-LKILTPLTDQTV- 444
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ + I LK I + P +W +G P+ DR+++ + L I +A D G+Y
Sbjct: 445 NLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 501
Query: 353 IQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQVDKSVTL 392
+ D A+ VT+ A DPP+ + D +VT+
Sbjct: 502 -----VFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTV 537
Score = 49.6 bits (113), Expect = 6e-05
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 2/97 (2%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
A PP ++V D +VT+ W PP G + Y++EY G W+ A KT
Sbjct: 716 AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 775
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ L ++ R+KA + G S P S P+ +
Sbjct: 776 KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 812
>U91629-1|AAC04620.1| 1274|Homo sapiens cardiac myosin binding
protein-C protein.
Length = 1274
Score = 121 bits (292), Expect = 1e-26
Identities = 95/390 (24%), Positives = 178/390 (45%), Gaps = 15/390 (3%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLE 146
P +S+ ++ T++W P +DGG P+ GY +E + S W+R ++ +
Sbjct: 778 PKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMI 837
Query: 147 PPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHV 206
Y+ RV A+N +G S S S + S+ + ++ + D T + V
Sbjct: 838 EGVVYEMRVYAVNAIGMSRPSPASQPF-MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERV 896
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCTATNRGGH 265
G+ ++ + + + + +T E TS+L+ + LP+ + + A N G
Sbjct: 897 GAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILV--KDLPTGARLLFRVRAHNMAGP 952
Query: 266 AV---TKARLCLEAA---PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
T + ++ P+L+ PR + ++ E + L GKP P + W +G
Sbjct: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
P+ ++ + I +P ++L I +A+R G YQ+ + ED A ++ V P PP++
Sbjct: 1013 PLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIE 438
+ VT +V L+W+PP D G ++ Y V+ W + R+T+ + +LI
Sbjct: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
Query: 439 GSEYKFRIKAESPYGMS-APSSESSPVRIP 467
G+ Y FR+ +++ G S ++ PV IP
Sbjct: 1132 GNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Query: 313 EWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
EW D + T+ R+ + T S+ + A++ D G Y + KN +GED V V
Sbjct: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI 769
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
PD P ++ + S T+ WEPPA DGG + YI+E + W++ ++
Sbjct: 770 DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQEL 829
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVE 479
+ +IEG Y+ R+ A + GMS PS S P G + LAVE
Sbjct: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVE 879
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P + + D ++LKW P G L GY VE G +EW+ +
Sbjct: 869 PPSEPTHLAV-EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR--LEDVTA 196
+++ L + FRV A N G ++ +TV Q P + + R + +
Sbjct: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV--QEILQRPRLQLPRHLRQTIQK 985
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V + F G P P + W K+ + + +I + ++L G +
Sbjct: 986 KVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPR 284
T R + KA L L+ K P+
Sbjct: 1045 VTV--RIENMEDKATLVLQVVDKPSPPQ 1070
Score = 51.6 bits (118), Expect = 1e-05
Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P PQ + + +D + L+W P G L GY V+ + EW T R
Sbjct: 1066 PSPPQDLRV-TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTH 1123
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPP-----------VF 187
V+ L + Y FRV + N VG S+ + + + + + + EPP F
Sbjct: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + + + G P P I+WFK+ ++ R + + + L +
Sbjct: 1184 TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKP 1243
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C ATN G A + RL
Sbjct: 1244 CPFDGGIYVCRATNLQGEARCECRL 1268
>AY518390-1|AAR89909.1| 1273|Homo sapiens myosin binding protein C,
cardiac protein.
Length = 1273
Score = 121 bits (292), Expect = 1e-26
Identities = 95/390 (24%), Positives = 178/390 (45%), Gaps = 15/390 (3%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLE 146
P +S+ ++ T++W P +DGG P+ GY +E + S W+R ++ +
Sbjct: 777 PKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMI 836
Query: 147 PPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHV 206
Y+ RV A+N +G S S S + S+ + ++ + D T + V
Sbjct: 837 EGVVYEMRVYAVNAIGMSRPSPASQPF-MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERV 895
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCTATNRGGH 265
G+ ++ + + + + +T E TS+L+ + LP+ + + A N G
Sbjct: 896 GAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILV--KDLPTGARLLFRVRAHNMAGP 951
Query: 266 AV---TKARLCLEAA---PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
T + ++ P+L+ PR + ++ E + L GKP P + W +G
Sbjct: 952 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1011
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
P+ ++ + I +P ++L I +A+R G YQ+ + ED A ++ V P PP++
Sbjct: 1012 PLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1070
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIE 438
+ VT +V L+W+PP D G ++ Y V+ W + R+T+ + +LI
Sbjct: 1071 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1130
Query: 439 GSEYKFRIKAESPYGMS-APSSESSPVRIP 467
G+ Y FR+ +++ G S ++ PV IP
Sbjct: 1131 GNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1160
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Query: 313 EWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
EW D + T+ R+ + T S+ + A++ D G Y + KN +GED V V
Sbjct: 709 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI 768
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
PD P ++ + S T+ WEPPA DGG + YI+E + W++ ++
Sbjct: 769 DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQEL 828
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVE 479
+ +IEG Y+ R+ A + GMS PS S P G + LAVE
Sbjct: 829 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVE 878
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P + + D ++LKW P G L GY VE G +EW+ +
Sbjct: 868 PPSEPTHLAV-EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 926
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR--LEDVTA 196
+++ L + FRV A N G ++ +TV Q P + + R + +
Sbjct: 927 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV--QEILQRPRLQLPRHLRQTIQK 984
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V + F G P P + W K+ + + +I + ++L G +
Sbjct: 985 KVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1043
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPR 284
T R + KA L L+ K P+
Sbjct: 1044 VTV--RIENMEDKATLVLQVVDKPSPPQ 1069
Score = 51.6 bits (118), Expect = 1e-05
Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P PQ + + +D + L+W P G L GY V+ + EW T R
Sbjct: 1065 PSPPQDLRV-TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTH 1122
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPP-----------VF 187
V+ L + Y FRV + N VG S+ + + + + + + EPP F
Sbjct: 1123 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1182
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + + + G P P I+WFK+ ++ R + + + L +
Sbjct: 1183 TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKP 1242
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C ATN G A + RL
Sbjct: 1243 CPFDGGIYVCRATNLQGEARCECRL 1267
>Y10129-1|CAA71216.1| 1274|Homo sapiens myosin binding protein C gene
protein.
Length = 1274
Score = 120 bits (288), Expect = 4e-26
Identities = 94/390 (24%), Positives = 178/390 (45%), Gaps = 15/390 (3%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLE 146
P +S+ ++ T++W P +DGG P+ GY +E + S W++ ++ +
Sbjct: 778 PKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQELSHEARRMI 837
Query: 147 PPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHV 206
Y+ RV A+N +G S S S + S+ + ++ + D T + V
Sbjct: 838 EGVVYEMRVYAVNAIGMSRPSPASQPF-MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERV 896
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCTATNRGGH 265
G+ ++ + + + + +T E TS+L+ + LP+ + + A N G
Sbjct: 897 GAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILV--KDLPTGARLLFRVRAHNMAGP 952
Query: 266 AV---TKARLCLEAA---PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
T + ++ P+L+ PR + ++ E + L GKP P + W +G
Sbjct: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
P+ ++ + I +P ++L I +A+R G YQ+ + ED A ++ V P PP++
Sbjct: 1013 PLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIE 438
+ VT +V L+W+PP D G ++ Y V+ W + R+T+ + +LI
Sbjct: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
Query: 439 GSEYKFRIKAESPYGMS-APSSESSPVRIP 467
G+ Y FR+ +++ G S ++ PV IP
Sbjct: 1132 GNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
Score = 87.0 bits (206), Expect = 3e-16
Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Query: 313 EWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
EW D + T+ R+ + T S+ + A++ D G Y + KN +GED V V
Sbjct: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI 769
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
PD P ++ + S T+ WEPPA DGG + YI+E + W++ ++
Sbjct: 770 DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQEL 829
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVE 479
+ +IEG Y+ R+ A + GMS PS S P G + LAVE
Sbjct: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVE 879
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P + + D ++LKW P G L GY VE G +EW+ +
Sbjct: 869 PPSEPTHLAV-EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR--LEDVTA 196
+++ L + FRV A N G ++ +TV Q P + + R + +
Sbjct: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV--QEILQRPRLQLPRHLRQTIQK 985
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V + F G P P + W K+ + + +I + ++L G +
Sbjct: 986 KVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPR 284
T R + KA L L+ K P+
Sbjct: 1045 VTV--RIENMEDKATLVLQVVDKPSPPQ 1070
Score = 51.6 bits (118), Expect = 1e-05
Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P PQ + + +D + L+W P G L GY V+ + EW T R
Sbjct: 1066 PSPPQDLRV-TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTH 1123
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPP-----------VF 187
V+ L + Y FRV + N VG S+ + + + + + + EPP F
Sbjct: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + + + G P P I+WFK+ ++ R + + + L +
Sbjct: 1184 TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKP 1243
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C ATN G A + RL
Sbjct: 1244 CPFDGGIYVCRATNLQGEARCECRL 1268
>X84075-1|CAA58882.1| 1274|Homo sapiens cardiac myosin-binding protein
C protein.
Length = 1274
Score = 120 bits (288), Expect = 4e-26
Identities = 94/390 (24%), Positives = 178/390 (45%), Gaps = 15/390 (3%)
Query: 87 PILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLE 146
P +S+ ++ T++W P +DGG P+ GY +E + S W++ ++ +
Sbjct: 778 PKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQELSHEARRMI 837
Query: 147 PPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHV 206
Y+ RV A+N +G S S S + S+ + ++ + D T + V
Sbjct: 838 EGVVYEMRVYAVNAIGMSRPSPASQPF-MPIGPPSEPTHLAVEDVSDTTVSLKWRPPERV 896
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI-KCTATNRGGH 265
G+ ++ + + + + +T E TS+L+ + LP+ + + A N G
Sbjct: 897 GAGGLDGYSVEYCPEGCSEWVAALQGLT--EHTSILV--KDLPTGARLLFRVRAHNMAGP 952
Query: 266 AV---TKARLCLEAA---PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
T + ++ P+L+ PR + ++ E + L GKP P + W +G
Sbjct: 953 GAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQ 1012
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
P+ ++ + I +P ++L I +A+R G YQ+ + ED A ++ V P PP++
Sbjct: 1013 PLAGEE-VSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPPQD 1071
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIE 438
+ VT +V L+W+PP D G ++ Y V+ W + R+T+ + +LI
Sbjct: 1072 LRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPELII 1131
Query: 439 GSEYKFRIKAESPYGMS-APSSESSPVRIP 467
G+ Y FR+ +++ G S ++ PV IP
Sbjct: 1132 GNGYYFRVFSQNMVGFSDRAATTKEPVFIP 1161
Score = 87.0 bits (206), Expect = 3e-16
Identities = 53/170 (31%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Query: 313 EWRHDGHPII-TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
EW D + T+ R+ + T S+ + A++ D G Y + KN +GED V V
Sbjct: 710 EWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVI 769
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKT 429
PD P ++ + S T+ WEPPA DGG + YI+E + W++ ++
Sbjct: 770 DVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMQLNFDLIQEL 829
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVE 479
+ +IEG Y+ R+ A + GMS PS S P G + LAVE
Sbjct: 830 SHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQPFMPIGPPSEPTHLAVE 879
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 8/208 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P + + D ++LKW P G L GY VE G +EW+ +
Sbjct: 869 PPSEPTHLAV-EDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGLTEHT 927
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR--LEDVTA 196
+++ L + FRV A N G ++ +TV Q P + + R + +
Sbjct: 928 SILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTV--QEILQRPRLQLPRHLRQTIQK 985
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ V + F G P P + W K+ + + +I + ++L G +
Sbjct: 986 KVGEPVNLLIPFQGKPRPQVTWTKEGQPL-AGEEVSIRNSPTDTILFIRAARRVHSGTYQ 1044
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPR 284
T R + KA L L+ K P+
Sbjct: 1045 VTV--RIENMEDKATLVLQVVDKPSPPQ 1070
Score = 51.6 bits (118), Expect = 1e-05
Identities = 51/205 (24%), Positives = 81/205 (39%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P PQ + + +D + L+W P G L GY V+ + EW T R
Sbjct: 1066 PSPPQDLRV-TDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWF-TVLEHYRRTH 1123
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELS-DVLTVSSDRASQEPP-----------VF 187
V+ L + Y FRV + N VG S+ + + + + + + EPP F
Sbjct: 1124 CVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSF 1183
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + + + G P P I+WFK+ ++ R + + + L +
Sbjct: 1184 TQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKP 1243
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C ATN G A + RL
Sbjct: 1244 CPFDGGIYVCRATNLQGEARCECRL 1268
>X64699-1|CAA45940.1| 531|Homo sapiens titin protein.
Length = 531
Score = 108 bits (260), Expect = 9e-23
Identities = 87/403 (21%), Positives = 162/403 (40%), Gaps = 12/403 (2%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI- 134
+P PP P++I I +++ L W+ +DGG ++GY VE + EW PP
Sbjct: 11 KPGPPNNPKVIDITR----SSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTG 66
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
+ + + + L H+Y FR+ A+N G ++++ + V + + + ++ + +
Sbjct: 67 INKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKII 126
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ V G P+P + W K D EI + +T+ S + L+ + D G+
Sbjct: 127 NIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS--SFTSLVLDNVNRYDSGK 184
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
T N G A + + P + + + + +I + ++ + +
Sbjct: 185 YTLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNY 242
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVT 371
+ + + KI + +++ A+N G A + V
Sbjct: 243 IVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVA 302
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV 431
P PP ++V SV+L W P DGG K+ YIVE W + +
Sbjct: 303 EVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 362
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMD 474
+ +L +G EY FR+ A + G S P S + P+ I+ D
Sbjct: 363 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPD 405
Score = 93.9 bits (223), Expect = 3e-18
Identities = 78/335 (23%), Positives = 141/335 (42%), Gaps = 15/335 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P+PP ++ I D ++++ W P DGG+ ++ Y VE R + +
Sbjct: 208 PSPPVNLKVTEITKD----SVSITWEPPLLDGGSKIKNYIVE-KREATRKSYAAVVTNCH 262
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ + L+ Y FRV A N+ G ++ +D + V+ +PP I ++DVT
Sbjct: 263 KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE---VPQPPGKIT-VDDVTR 318
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
G S I + + S + + +S ++ + + +E +
Sbjct: 319 NSVSLSWTKPEHDG-GSKIIQYIVEMQAKHSEKWSECARVKSLQAVITN-LTQGEEYLFR 376
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL---YEINETIFLKTTIVGKPTPTIE 313
A N G + ++ A L + ++ + + ++ I G+P PTI
Sbjct: 377 VVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKMEVPIFGRPKPTIT 436
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DG P+ RI ++ + + L I + D G+Y I N++G+ TA+ +
Sbjct: 437 WTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 496
Query: 374 PDPPRN-VSVTRQVDKSVTLDWEPPADDGGCKVGN 407
PDPP+ V +S+TL W PP GGC++ N
Sbjct: 497 PDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITN 531
Score = 73.3 bits (172), Expect = 4e-12
Identities = 60/218 (27%), Positives = 90/218 (41%), Gaps = 10/218 (4%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K A P PPGK + D N+++L W HDGG+ + Y VE S +W A
Sbjct: 300 KVAEVPQPPGKITV----DDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 355
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
V + V+T L +Y FRV A+N+ G S+ L+ V V+ D EP V
Sbjct: 356 R--VKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLA-VPIVAKDLVI-EPDV-KPAF 410
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
+ ++ V G P PTI W KD + + R +T + L + D
Sbjct: 411 SSYSVQVGQDLKMEVPIFGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDD 470
Query: 252 EGEIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYED 288
G+ T N G + L+ + P +++D
Sbjct: 471 GGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDD 508
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/116 (32%), Positives = 52/116 (44%), Gaps = 5/116 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTN 430
P PP N V SV L W P DGGC++ YIVE W + KTN
Sbjct: 12 PGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTN 71
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR--AIDMDFLAVEARIIN 484
+ + L+E EY FRI A + G+ + P+ + + A D+D +IIN
Sbjct: 72 IEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN 127
>AK095113-1|BAC04488.1| 903|Homo sapiens protein ( Homo sapiens
cDNA FLJ37794 fis, clone BRHIP3000488. ).
Length = 903
Score = 105 bits (251), Expect = 1e-21
Identities = 90/347 (25%), Positives = 146/347 (42%), Gaps = 24/347 (6%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
EL++ + ++ V A+ D + Y + ++TV A+ + + DV A
Sbjct: 474 ELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTA-IVTVEERLATVK-----SGMSDVHAAT 527
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
E V + + W KD EI I + L+F + P EG+
Sbjct: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGVQIVKQGAVHKLIFPSMGPEHEGKY--- 583
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYE----DGLLYEINETIFLKTTIVGKPTPTIEW 314
T R ++A + + P + P E + ++ T +K GKP P + W
Sbjct: 584 -TFRAKGTESEASVFIADPPTID-PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
DG + ++R+ + ++L I + R D G ++ KN G TA ++V PP
Sbjct: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLEPP 701
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKTNVT 432
VT ++VT+ W P DGG V YIVE + G N+W+ + T T
Sbjct: 702 GFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCT 761
Query: 433 LFDLIEGSEYKFRIKAESPYGMSAPSSESS------PVRIPGRAIDM 473
+ L+E +EY+FR+ A + G PS SS PV+ PG D+
Sbjct: 762 VDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKDPVKPPGLVQDL 808
Score = 60.9 bits (141), Expect = 2e-08
Identities = 64/286 (22%), Positives = 108/286 (37%), Gaps = 23/286 (8%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T V F G P P + W+KD E+ R ++ E ++L + D G
Sbjct: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--T 311
I N G A L + P Q D + T T G P
Sbjct: 677 LILLKLKNDHGSATATLHLSVLEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYI 736
Query: 312 IEWRHDGHPI---ITDDRIEISITPKFSVL-------KIHSAKRSDRGEYQIQAKNIIGE 361
+E R G + + D I+ + +L ++ + ++ G+ + + +++ +
Sbjct: 737 VERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAK 796
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
D PP +++ V+ + S++L W PA+ G YI+E + W
Sbjct: 797 DPVK-------PPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMWAEDTKEWS 847
Query: 422 KA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
K I T T+ LIE +Y FRI+A + G+ P VR
Sbjct: 848 KCTKIPISGTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVR 893
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG P ++D A+T+ W T DGGAP+ GY VE + GS W+ +
Sbjct: 700 PPGFASQ-PQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGT 758
Query: 139 ELVLTGLEPPHKYQFRVAALNDVG 162
+ + GL +Y+FRV A+N G
Sbjct: 759 KCTVDGLLEDTEYEFRVIAVNKAG 782
Score = 47.2 bits (107), Expect = 3e-04
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
+ND G + S + D + EP F+ ++ V E F + S P
Sbjct: 302 MNDAGIYSLS-VGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFV 359
Query: 218 WFKDDYEIFSSRRTAITTDES--TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
W + E+ + IT E T L SD GE A G+ V KA+L ++
Sbjct: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P +++ ++ + E + L+ + K T+ W+ DG ++ + ++ K
Sbjct: 416 RIP-IKFVSNLKNVRVKERSRAC-LECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKQ 472
Query: 336 SVLKIHSAKRSDRGEYQIQA 355
+ L I A+ SD GEY + A
Sbjct: 473 AELIIEDAQLSDGGEYTVVA 492
Score = 41.1 bits (92), Expect = 0.021
Identities = 32/124 (25%), Positives = 52/124 (41%), Gaps = 3/124 (2%)
Query: 164 SNYSELSDVLTVSSD-RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD 222
S+ E ++T SS+ A P +++ + VTA E DK F G P I+W ++
Sbjct: 45 SSIVEFFSLVTRSSNIPAGDSVPELVEKPQPVTAPEGDKAVFRARVQGNAKPHISWKRES 104
Query: 223 -YEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV-TKARLCLEAAPKL 280
I S + + VL + D KC A+N A+ T + L E K+
Sbjct: 105 GIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKM 164
Query: 281 RYPR 284
+ +
Sbjct: 165 DFKK 168
Score = 38.7 bits (86), Expect = 0.11
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNII 359
+ K P W+ +G + DD+ EI+++ LKI A+ SD GE+ +A N++
Sbjct: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
Score = 37.1 bits (82), Expect = 0.34
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PPG Q + + SD ++I+L W G P GY +E + EW + +
Sbjct: 801 PPGLVQDLHV-SDSSNSSISLAWREPAE--GDPPSGYILEMWAEDTKEWSKCTKIPISGT 857
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSEL 169
+ GL KY FR+ A+N+ G EL
Sbjct: 858 CYTVGGLIERQKYFFRIRAVNEAGVGEPVEL 888
>BC131529-1|AAI31530.1| 868|Homo sapiens eEF1A2 binding protein
protein.
Length = 868
Score = 104 bits (249), Expect = 2e-21
Identities = 106/405 (26%), Positives = 164/405 (40%), Gaps = 26/405 (6%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
A P P ILS ITL W G A + GY +E + GS W V
Sbjct: 359 ALPKAPSAPAILSASS-QGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPE 417
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+ + +Y+FRV A+ G SD + R PP ++ L+ VT
Sbjct: 418 RRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFA---RDPMRPPGLVRNLQ-VTDR 473
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDY--EIFSSRRTA-ITTDESTSVLLFHQILPSDEGE 254
N + ++++G P Y E+ SS + T + + GE
Sbjct: 474 SNTSIT--LSWAG-PDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGE 530
Query: 255 ---IKCTATNRGGHAVTKARLCLEAA------PKLRYPRQYEDGLLYEINETIFLKTTIV 305
++ TA N GG + A L A PK +D L ++ +T+ + +
Sbjct: 531 GYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFE 590
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W DG P+ + +++T + L I A SD G Y + + + G++ A
Sbjct: 591 AMPMPEVTWLKDGLPL---PKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVA 647
Query: 365 -AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+F + V A P P + + V +VT +WEP D+ +Y V + W +A
Sbjct: 648 HSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEA 707
Query: 424 ITSRKTN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
TN TL ++ G EY FR+ A++ G S PS S P IP
Sbjct: 708 ADRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIP 752
Score = 80.6 bits (190), Expect = 3e-14
Identities = 65/290 (22%), Positives = 119/290 (41%), Gaps = 9/290 (3%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L D+ + T + P WFKD ++ + D L
Sbjct: 75 FSQGLADMEVQPGEAATLSCTLTSDLGPG-TWFKDGVKLTTQDGVIFKQDGLVHSLFITH 133
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ + G A ++ A + AP + + + L+ + + + +K
Sbjct: 134 VQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVT--EKLREPLVVKAGKPVIVKIPFQS 191
Query: 307 KPTPTIEWRHDGHPII--TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
WR DG ++ +D ++ + ++ L + SA R D G+Y + ++ G A
Sbjct: 192 HLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQA 251
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ V PDPP+ + ++ V L W PP D+GG V Y+VE + G + WLK
Sbjct: 252 ELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKV 311
Query: 424 ITSRKTNVTLFDL-IE-GSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI 471
+ + T D +E G +Y FR++A + G + + ES + + A+
Sbjct: 312 GEAPADSTTFTDAHVEPGRKYTFRVRAVTSEG-AGEALESEEILVAPEAL 360
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 16/198 (8%)
Query: 89 LSDDEPNAITLKWAPATHDG-GAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEP 147
L ++ P +T +W P+ + PL Y V W A I L G+ P
Sbjct: 666 LQENVPGTVTAEWEPSPDEAQDVPLH-YAVFTRSSAHGPWHEAADRIYTN-RFTLLGILP 723
Query: 148 PHKYQFRVAALNDVGHSNYSELSDVLTVSSDR--------ASQEP-----PVFIKRLEDV 194
H+Y FRV A N++G S S+ S + R +EP P F+ L
Sbjct: 724 GHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSH 783
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ + G P P + WFK+D + + T L + P D GE
Sbjct: 784 LLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGE 843
Query: 255 IKCTATNRGGHAVTKARL 272
K A N G AV+ A L
Sbjct: 844 YKAVAENTLGQAVSTATL 861
Score = 50.4 bits (115), Expect = 3e-05
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
++ LV A P P ++ + +TL W P G + Y++E + G N W
Sbjct: 349 ESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTW- 407
Query: 422 KAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
A+ + + T+ D+ +G +Y+FR+ A +P G P S V
Sbjct: 408 TAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAV 453
Score = 46.0 bits (104), Expect = 7e-04
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 5/122 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P + D + L+W P +GG + Y VE + G + W++
Sbjct: 260 KPDPPQGPMEV---QDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPA 316
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV--SSDRASQEPPVFIKRLED 193
+EP KY FRV A+ G E ++L + +A P + +
Sbjct: 317 DSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQG 376
Query: 194 VT 195
+T
Sbjct: 377 IT 378
Score = 43.6 bits (98), Expect = 0.004
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
A F PP RN+ VT + + S+TL W P G + Y+VE + WL
Sbjct: 452 AVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPC 511
Query: 424 I--TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEAR 481
T T T L G Y R+ A + G S PS+ + V+ + FL +
Sbjct: 512 HVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSS- 570
Query: 482 IINEALTREDGEEPRI 497
+ LT + G+ R+
Sbjct: 571 -TKDLLTVKVGDTVRV 585
>AY245430-1|AAO92932.1| 868|Homo sapiens eEF1A2 binding protein
protein.
Length = 868
Score = 104 bits (249), Expect = 2e-21
Identities = 106/405 (26%), Positives = 164/405 (40%), Gaps = 26/405 (6%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
A P P ILS ITL W G A + GY +E + GS W V
Sbjct: 359 ALPKAPSAPAILSASS-QGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPE 417
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTAL 197
+ + +Y+FRV A+ G SD + R PP ++ L+ VT
Sbjct: 418 RRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFA---RDPMRPPGLVRNLQ-VTDR 473
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDY--EIFSSRRTA-ITTDESTSVLLFHQILPSDEGE 254
N + ++++G P Y E+ SS + T + + GE
Sbjct: 474 SNTSIT--LSWAG-PDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGE 530
Query: 255 ---IKCTATNRGGHAVTKARLCLEAA------PKLRYPRQYEDGLLYEINETIFLKTTIV 305
++ TA N GG + A L A PK +D L ++ +T+ + +
Sbjct: 531 GYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFE 590
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P + W DG P+ + +++T + L I A SD G Y + + + G++ A
Sbjct: 591 AMPMPEVTWLKDGLPL---PKRSVTVTKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVA 647
Query: 365 -AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+F + V A P P + + V +VT +WEP D+ +Y V + W +A
Sbjct: 648 HSFRIRVAACPQAPGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEA 707
Query: 424 ITSRKTN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
TN TL ++ G EY FR+ A++ G S PS S P IP
Sbjct: 708 ADRIYTNRFTLLGILPGHEYHFRVVAKNELGASKPSDTSQPWCIP 752
Score = 80.6 bits (190), Expect = 3e-14
Identities = 65/290 (22%), Positives = 119/290 (41%), Gaps = 9/290 (3%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L D+ + T + P WFKD ++ + D L
Sbjct: 75 FSQGLADMEVQPGEAATLSCTLTSDLGPG-TWFKDGVKLTTQDGVIFKQDGLVHSLFITH 133
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
+ + G A ++ A + AP + + + L+ + + + +K
Sbjct: 134 VQGTQAGRYTFVAGDQQSEATLTVQDSPTIAPDVT--EKLREPLVVKAGKPVIVKIPFQS 191
Query: 307 KPTPTIEWRHDGHPII--TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
WR DG ++ +D ++ + ++ L + SA R D G+Y + ++ G A
Sbjct: 192 HLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQA 251
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKS-VTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
+ V PDPP+ + ++ V L W PP D+GG V Y+VE + G + WLK
Sbjct: 252 ELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKV 311
Query: 424 ITSRKTNVTLFDL-IE-GSEYKFRIKAESPYGMSAPSSESSPVRIPGRAI 471
+ + T D +E G +Y FR++A + G + + ES + + A+
Sbjct: 312 GEAPADSTTFTDAHVEPGRKYTFRVRAVTSEG-AGEALESEEILVAPEAL 360
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/198 (26%), Positives = 75/198 (37%), Gaps = 16/198 (8%)
Query: 89 LSDDEPNAITLKWAPATHDG-GAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEP 147
L ++ P +T +W P+ + PL Y V W A I L G+ P
Sbjct: 666 LQENVPGTVTAEWEPSPDEAQDVPLH-YAVFTRSSAHGPWHEAADRIYTN-RFTLLGILP 723
Query: 148 PHKYQFRVAALNDVGHSNYSELSDVLTVSSDR--------ASQEP-----PVFIKRLEDV 194
H+Y FRV A N++G S S+ S + R +EP P F+ L
Sbjct: 724 GHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSH 783
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
+ + G P P + WFK+D + + T L + P D GE
Sbjct: 784 LLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGE 843
Query: 255 IKCTATNRGGHAVTKARL 272
K A N G AV+ A L
Sbjct: 844 YKAVAENTLGQAVSTATL 861
Score = 50.4 bits (115), Expect = 3e-05
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
++ LV A P P ++ + +TL W P G + Y++E + G N W
Sbjct: 349 ESEEILVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTW- 407
Query: 422 KAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
A+ + + T+ D+ +G +Y+FR+ A +P G P S V
Sbjct: 408 TAVNDQPVPERRWTVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAV 453
Score = 46.0 bits (104), Expect = 7e-04
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 5/122 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PP P + D + L+W P +GG + Y VE + G + W++
Sbjct: 260 KPDPPQGPMEV---QDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPA 316
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV--SSDRASQEPPVFIKRLED 193
+EP KY FRV A+ G E ++L + +A P + +
Sbjct: 317 DSTTFTDAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAPAILSASSQG 376
Query: 194 VT 195
+T
Sbjct: 377 IT 378
Score = 43.6 bits (98), Expect = 0.004
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
A F PP RN+ VT + + S+TL W P G + Y+VE + WL
Sbjct: 452 AVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPC 511
Query: 424 I--TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEAR 481
T T T L G Y R+ A + G S PS+ + V+ + FL +
Sbjct: 512 HVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFLVDSS- 570
Query: 482 IINEALTREDGEEPRI 497
+ LT + G+ R+
Sbjct: 571 -TKDLLTVKVGDTVRV 585
>L05606-1|AAA36339.1| 476|Homo sapiens protein ( Human myosin
binding protein H mRNA, complete cds. ).
Length = 476
Score = 101 bits (242), Expect = 1e-20
Identities = 55/184 (29%), Positives = 89/184 (48%), Gaps = 2/184 (1%)
Query: 277 APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS 336
APK+R PR + ++ ET+ L+ GKP P W H+GH + R+ + + S
Sbjct: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
Query: 337 VLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEP 396
+L I SA+RSD G Y++ + E A + V P PP ++ + + L W P
Sbjct: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
Query: 397 PADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
P D G ++ Y+V+ W + T T+ DLI G+ Y FR+ +E+ G+S
Sbjct: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Query: 456 APSS 459
++
Sbjct: 350 TSAT 353
Score = 65.7 bits (153), Expect = 8e-10
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 9/192 (4%)
Query: 73 SAGRPAPPGKP----QIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
+A +PAPP + ++ L D +++T+ W P G L+GY +E R G++EW+
Sbjct: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ ++ + + L K+ RV+A++ G + L + + + + P + +
Sbjct: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN--IEAPKIRV 176
Query: 189 KRLEDVTALE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
R T + + V + F G P P W + + + S+R ++ T + S+L
Sbjct: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRS 235
Query: 247 ILPSDEGEIKCT 258
SD G + T
Sbjct: 236 AQRSDSGRYELT 247
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW--LKAITSRKTNV 431
P P +++ SVT+ WEPP G + Y++E R G + W + A T
Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ +L G ++ R+ A S G P+ P+ I
Sbjct: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
Score = 43.6 bits (98), Expect = 0.004
Identities = 50/210 (23%), Positives = 81/210 (38%), Gaps = 15/210 (7%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +L NA L+W P G L GY V+ + +W T
Sbjct: 267 PGPPSSIRLLDVWGCNA-ALQWTPPQDTGNTELLGYMVQKADKKTGQWF-TVLERYHPTT 324
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT------VSS------DRASQEPPVF 187
++ L + Y FRV + N G S + ++ L +++ +R E P F
Sbjct: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L D T+ + + + I W K+ EI + + +++ L +
Sbjct: 385 TQPLADHTSTPGYSTQLFCSVE-LHQAKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 443
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
P D G C A N G A RL ++A+
Sbjct: 444 SPFDSGVYTCKAINVLGEASVDCRLEVKAS 473
>BC044226-1|AAH44226.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 101 bits (242), Expect = 1e-20
Identities = 55/184 (29%), Positives = 89/184 (48%), Gaps = 2/184 (1%)
Query: 277 APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS 336
APK+R PR + ++ ET+ L+ GKP P W H+GH + R+ + + S
Sbjct: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
Query: 337 VLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEP 396
+L I SA+RSD G Y++ + E A + V P PP ++ + + L W P
Sbjct: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTP 289
Query: 397 PADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
P D G ++ Y+V+ W + T T+ DLI G+ Y FR+ +E+ G+S
Sbjct: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Query: 456 APSS 459
++
Sbjct: 350 TSAT 353
Score = 65.7 bits (153), Expect = 8e-10
Identities = 44/192 (22%), Positives = 86/192 (44%), Gaps = 9/192 (4%)
Query: 73 SAGRPAPPGKP----QIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
+A +PAPP + ++ L D +++T+ W P G L+GY +E R G++EW+
Sbjct: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWV 118
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ ++ + + L K+ RV+A++ G + L + + + + P + +
Sbjct: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN--IEAPKIRV 176
Query: 189 KRLEDVTALE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
R T + + V + F G P P W + + + S+R ++ T + S+L
Sbjct: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRS 235
Query: 247 ILPSDEGEIKCT 258
SD G + T
Sbjct: 236 AQRSDSGRYELT 247
Score = 52.8 bits (121), Expect = 6e-06
Identities = 52/210 (24%), Positives = 82/210 (39%), Gaps = 14/210 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +L NA L+W P G L GY V+ + +W T
Sbjct: 267 PGPPSSIRLLDVWGCNA-ALQWTPPQDTGNTELLGYMVQKADKKTGQWF-TVLERYHPTT 324
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT------VSS------DRASQEPPVF 187
++ L + Y FRV + N G S + ++ L +++ +R E P F
Sbjct: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L D T+ + + P P I W K+ EI + + +++ L +
Sbjct: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
P D G C A N G A RL ++A+
Sbjct: 445 SPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW--LKAITSRKTNV 431
P P +++ SVT+ WEPP G + Y++E R G + W + A T
Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ +L G ++ R+ A S G P+ P+ I
Sbjct: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHI 165
>X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein.
Length = 1138
Score = 99 bits (238), Expect = 4e-20
Identities = 102/431 (23%), Positives = 178/431 (41%), Gaps = 45/431 (10%)
Query: 55 HYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRG 114
H + + A + ++ K P PP P + + DD + W P +DGG+P+ G
Sbjct: 596 HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV-GDDW---CIMNWEPPAYDGGSPILG 651
Query: 115 YQVECNRLGSTEWIR----TAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
Y +E + S+ W+R P+ ++ G+ Y+ R+ A+N +G S S S
Sbjct: 652 YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV----AYEVRIFAVNAIGISKPSMPS 707
Query: 171 DVLTVSSDRASQEPPVF--IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS 228
A PP + + D T + H+ +G+ + + +E +S
Sbjct: 708 RPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC---FEGSTS 761
Query: 229 RRTAITTDESTSVLLFHQILPSDEGEI---KCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
+ + E+ L + +++ I K T T A R+ A P+
Sbjct: 762 AKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY 821
Query: 286 YEDGLLY-------EINETIFLKTTIV--------------GKPTPTIEWRHDGHPIITD 324
Y +L +I+ LK T + GKP P + W+ DG I
Sbjct: 822 YSQPILVKEIIEPPKIHSPKHLKQTYIRRVGDRVILVIPFQGKPRPELTWKKDGAE-IDK 880
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR 384
++I I + +++ I A+RS G+Y +Q K +TA+ + + P PP+ V +
Sbjct: 881 NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIRIIDRPGPPQIVKIED 940
Query: 385 QVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKF 444
++V L W PP DDG + Y ++ WL+ I V +L+ G+EY F
Sbjct: 941 VWGRNVALTWTPPKDDGNAAITGYTIQKADKKSMEWLRVIEHIIEPVPHTELVIGNEYYF 1000
Query: 445 RIKAESPYGMS 455
R+ +E+ G+S
Sbjct: 1001 RVFSENMCGLS 1011
Score = 91.1 bits (216), Expect = 2e-17
Identities = 72/250 (28%), Positives = 104/250 (41%), Gaps = 6/250 (2%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W K+ + S R + L+ L DEG+ + A++ +
Sbjct: 462 WTKNGLPVQESDRLKVVHKGRIHKLVIDHALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 519
Query: 278 PKLRYPRQYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKF 335
PK+ D + I + L+ I G+P P W I+ RI P
Sbjct: 520 PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 579
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
S L I A+R D G Y I KN GE A+ V V PDPP +VT D ++WE
Sbjct: 580 STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWE 639
Query: 396 PPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
PPA DGG + Y +E + + W++ ++T +IEG Y+ RI A + G
Sbjct: 640 PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 699
Query: 454 MSAPSSESSP 463
+S PS S P
Sbjct: 700 ISKPSMPSRP 709
Score = 56.8 bits (131), Expect = 4e-07
Identities = 54/205 (26%), Positives = 80/205 (39%), Gaps = 15/205 (7%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQI+ I D + L W P DG A + GY ++ S EW+R I+
Sbjct: 930 PGPPQIVKI-EDVWGRNVALTWTPPKDDGNAAITGYTIQKADKKSMEWLRVIEHII--EP 986
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL---SDVLT---------VSSDRASQEPPVF 187
+ T L ++Y FRV + N G S + + S V+ V D E P+F
Sbjct: 987 VPHTELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1046
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + + + G P P I W K+ I R + ++ L +
Sbjct: 1047 TQPLVNRLCHSGYMATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNLGVCTLEIGKP 1106
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G + +L
Sbjct: 1107 SPYDGGTYCCKAVNDLGTVEIECKL 1131
Score = 46.4 bits (105), Expect = 6e-04
Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 22/222 (9%)
Query: 176 SSDRASQEPPVFI-KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAI 233
S++ +EPP+ + K+LED T ++VE S + WFK+ EI + R I
Sbjct: 331 STELLVREPPIMVTKQLEDTTDYCGERVELECEVSE-DDAQVKWFKNGEEIILVQTRYRI 389
Query: 234 TTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE 293
+ +L+ +D + T GG + A+L ++ P L+ D +
Sbjct: 390 RVEGKKHILIIEGATKADAADYSVMTT--GGQS--SAKLSVDLKP-LKILTPLTDQTV-N 443
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
+ + I LK I + P +W +G P+ DR+++ + L I A D G+Y
Sbjct: 444 LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIDHALTEDEGDY-- 499
Query: 354 QAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQVDKSVTL 392
+ D A+ VT+ A DPP+ + D +VT+
Sbjct: 500 ----VFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTV 535
>BC132902-1|AAI32903.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 99.5 bits (237), Expect = 6e-20
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 2/183 (1%)
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+E PK+ PR + ++ +T+ L GKP P W HDG + T R+ +
Sbjct: 47 IEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGE 105
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ S+L I A+R+D G YQ++ + E TA + V P PP+++ + S TL+
Sbjct: 106 QDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
Query: 394 WEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPY 452
W PP D G + Y V+ T +W + +T+ + DLI G+ Y FR+ AE+
Sbjct: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQC 225
Query: 453 GMS 455
G+S
Sbjct: 226 GLS 228
Score = 51.2 bits (117), Expect = 2e-05
Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ I ++ D + TL+W P G L GY V+ S W T R
Sbjct: 146 PGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRTS 203
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL-------TVS-----SDRASQEPPVF 187
+++ L + Y FRV A N G S + ++ L TV + R E P F
Sbjct: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + T + + P P I W K+ +I + + T L +
Sbjct: 264 TQPLANCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G A R+
Sbjct: 324 GPFDGGIYTCKAVNPLGEASVDCRV 348
>BC132900-1|AAI32901.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 99.5 bits (237), Expect = 6e-20
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 2/183 (1%)
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+E PK+ PR + ++ +T+ L GKP P W HDG + T R+ +
Sbjct: 47 IEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGE 105
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ S+L I A+R+D G YQ++ + E TA + V P PP+++ + S TL+
Sbjct: 106 QDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
Query: 394 WEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPY 452
W PP D G + Y V+ T +W + +T+ + DLI G+ Y FR+ AE+
Sbjct: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQC 225
Query: 453 GMS 455
G+S
Sbjct: 226 GLS 228
Score = 51.2 bits (117), Expect = 2e-05
Identities = 54/205 (26%), Positives = 77/205 (37%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ I ++ D + TL+W P G L GY V+ S W T R
Sbjct: 146 PGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRTS 203
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL-------TVS-----SDRASQEPPVF 187
+++ L + Y FRV A N G S + ++ L TV + R E P F
Sbjct: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L + T + + P P I W K+ +I + + T L +
Sbjct: 264 TQPLANCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G A R+
Sbjct: 324 GPFDGGIYTCKAVNPLGEASVDCRV 348
>AL390252-10|CAI13179.1| 354|Homo sapiens myosin binding protein
H-like protein.
Length = 354
Score = 99.5 bits (237), Expect = 6e-20
Identities = 57/183 (31%), Positives = 91/183 (49%), Gaps = 2/183 (1%)
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+E PK+ PR + ++ +T+ L GKP P W HDG + T R+ +
Sbjct: 47 IEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGE 105
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ S+L I A+R+D G YQ++ + E TA + V P PP+++ + S TL+
Sbjct: 106 QDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
Query: 394 WEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPY 452
W PP D G + Y V+ T +W + +T+ + DLI G+ Y FR+ AE+
Sbjct: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQC 225
Query: 453 GMS 455
G+S
Sbjct: 226 GLS 228
Score = 53.2 bits (122), Expect = 5e-06
Identities = 55/205 (26%), Positives = 77/205 (37%), Gaps = 14/205 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG PQ I ++ D + TL+W P G L GY V+ S W T R
Sbjct: 146 PGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRTS 203
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL-------TVS-----SDRASQEPPVF 187
+++ L + Y FRV A N G S + ++ L TV + R E P F
Sbjct: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L D T + + P P I W K+ +I + + T L +
Sbjct: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
Query: 248 LPSDEGEIKCTATNRGGHAVTKARL 272
P D G C A N G A R+
Sbjct: 324 GPFDGGIYTCKAVNPLGEASVDCRV 348
>U27266-1|AAB86737.1| 477|Homo sapiens myosin binding protein H
protein.
Length = 477
Score = 99.1 bits (236), Expect = 7e-20
Identities = 55/184 (29%), Positives = 88/184 (47%), Gaps = 2/184 (1%)
Query: 277 APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS 336
APK+R PR + ++ ET+ L+ GKP P W H+GH + R+ + + S
Sbjct: 171 APKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDS 229
Query: 337 VLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEP 396
+L I SA+RSD G Y++ + E A + V P PP + + + L W P
Sbjct: 230 ILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPCCIRLLDVWGCNAALQWTP 289
Query: 397 PADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYKFRIKAESPYGMS 455
P D G ++ Y+V+ W + T T+ DLI G+ Y FR+ +E+ G+S
Sbjct: 290 PQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349
Query: 456 APSS 459
++
Sbjct: 350 TSAT 353
Score = 64.5 bits (150), Expect = 2e-09
Identities = 44/192 (22%), Positives = 84/192 (43%), Gaps = 9/192 (4%)
Query: 73 SAGRPAPPGKP----QIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
+A +PAPP + ++ L D +++T+ W P G L+GY +E R G +EW+
Sbjct: 59 TATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGGSEWV 118
Query: 129 RTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFI 188
+ ++ + + L K+ RV+A+ G + L + + + + P + +
Sbjct: 119 PVSARPMMVTQQTVRNLALGDKFLLRVSAVRPAGAGPPAMLDQPIHIREN--IEAPKIRV 176
Query: 189 KRLEDVTALE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
R T + + V + F G P P W + + + S+R ++ T + S+L
Sbjct: 177 PRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL-DSQRVSMRTGDQDSILFIRS 235
Query: 247 ILPSDEGEIKCT 258
SD G + T
Sbjct: 236 AQRSDSGRYELT 247
Score = 52.0 bits (119), Expect = 1e-05
Identities = 52/210 (24%), Positives = 82/210 (39%), Gaps = 14/210 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P I +L NA L+W P G L GY V+ + +W T
Sbjct: 267 PGPPCCIRLLDVWGCNA-ALQWTPPQDTGNTELLGYMVQKADKKTGQWF-TVLERYHPTT 324
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT------VSS------DRASQEPPVF 187
++ L + Y FRV + N G S + ++ L +++ +R E P F
Sbjct: 325 CTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSF 384
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
+ L D T+ + + P P I W K+ EI + + +++ L +
Sbjct: 385 TQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKP 444
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
P D G C A N G A RL ++A+
Sbjct: 445 SPFDSGVYTCKAINVLGEASVDCRLEVKAS 474
Score = 47.2 bits (107), Expect = 3e-04
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW--LKAITSRKTNV 431
P P +++ SVT+ WEPP G + Y++E R G + W + A T
Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGGSEWVPVSARPMMVTQQ 130
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
T+ +L G ++ R+ A P G P+ P+ I
Sbjct: 131 TVRNLALGDKFLLRVSAVRPAGAGPPAMLDQPIHI 165
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 98.7 bits (235), Expect = 1e-19
Identities = 56/180 (31%), Positives = 83/180 (46%), Gaps = 6/180 (3%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-----VLKIHSAKRSDR 348
+ +T+ L+ + G+P PTI W+ I+ D + T LKI + D
Sbjct: 787 LGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDS 846
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNY 408
G Y A N G + + V V P P + SV L W PP+ G C + Y
Sbjct: 847 GIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGY 906
Query: 409 IVEYYRTGWNVWLKAITSR-KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
VEY G +W +++ S T + + DL G Y+FR+ A +P+G+S PS S VR+P
Sbjct: 907 TVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVRLP 966
Score = 52.4 bits (120), Expect = 8e-06
Identities = 35/100 (35%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Query: 72 KSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTA 131
K G PA P +P I + ++ L+W P + G + GY VE GS W ++
Sbjct: 867 KVQGVPAAPNRP----IAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSV 922
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
L LV+ L P YQFRV+A N G S SE S+
Sbjct: 923 AS-TLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSE 961
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/99 (32%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-----SSRRTAITTDEST 239
P F+ L DVT L D V G P PTI W D I S+ T + D
Sbjct: 774 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGE 833
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
L ++P D G C ATN G T A + ++ P
Sbjct: 834 ITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVP 872
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 95.9 bits (228), Expect = 7e-19
Identities = 69/237 (29%), Positives = 111/237 (46%), Gaps = 11/237 (4%)
Query: 160 DVGHSNYSELSDVL--TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
D+G +DV T A + PP F+K+L D++ + +V+ T G ++
Sbjct: 4130 DIGEYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV 4189
Query: 218 WFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-LE 275
WFKD EI S I+ E+ + L F ++ P++ G+ C N G A L LE
Sbjct: 4190 WFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE 4249
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
A + P + + +T L+ T+ G P + +W DG + +D++ +IS K
Sbjct: 4250 PATIVEKP----ESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKV 4305
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGED--TAAFLVT-VTAPPDPPRNVSVTRQVDKS 389
S LKI + SD G Y + +N +G+D TA+ V+ T PP R + T + S
Sbjct: 4306 SGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGS 4362
Score = 95.1 bits (226), Expect = 1e-18
Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 8/207 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP FI+ L+ V ++ VE +G P + W K++ EI SS++ +T S
Sbjct: 1617 KEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN 1676
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + PSD GE +C +N GG R+ L+ P + ++ E+ + + +
Sbjct: 1677 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPS--FIKKIENTTTV-LKSSATFQ 1733
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG- 360
+T+ G P +I W D + DD + IS + L+I S G Y QAKN G
Sbjct: 1734 STVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGV 1793
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVD 387
E AFL+ +P + V + VD
Sbjct: 1794 ERCYAFLLV----QEPAQIVEKAKSVD 1816
Score = 91.1 bits (216), Expect = 2e-17
Identities = 55/193 (28%), Positives = 87/193 (45%), Gaps = 3/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
QEPP F+K E + L V F G P + WF+ E+ R I +++ +
Sbjct: 2555 QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAE 2614
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I S GE C +N G A RL ++ P R + + E ++I L+
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE-PAAFLKRLSDHSV--EPGKSIILE 2671
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+T G ++ W+ DG I T ++ I T K +L+I ++ + D G+Y + +N G
Sbjct: 2672 STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGR 2731
Query: 362 DTAAFLVTVTAPP 374
D LV+ PP
Sbjct: 2732 DVCGALVSTLEPP 2744
Score = 91.1 bits (216), Expect = 2e-17
Identities = 49/193 (25%), Positives = 91/193 (47%), Gaps = 3/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+++ + + L V F G P +++WFK E+ R ++ ++S +
Sbjct: 4437 REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAE 4496
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + S GE C +N G A L ++A K + ++ D + E + + L+
Sbjct: 4497 LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK--FVKRLNDYSI-EKGKPLILE 4553
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T G P ++ W+ +G + R I+ T K +L+I S+ D G+Y +N G+
Sbjct: 4554 GTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGK 4613
Query: 362 DTAAFLVTVTAPP 374
D+ + + + PP
Sbjct: 4614 DSCSAQILILEPP 4626
Score = 88.6 bits (210), Expect = 1e-16
Identities = 62/236 (26%), Positives = 107/236 (45%), Gaps = 11/236 (4%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
+++ T + +Y F V NDVG S+ +VL + PP F K+L+ + +++
Sbjct: 1302 KIISTEKKDSGEYTFEVQ--NDVGRSSCKARINVLDLII------PPSFTKKLKKMDSIK 1353
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
++ +G +I WFKDD EI +S + + ++T+ L Q+ +D G C+
Sbjct: 1354 GSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCS 1413
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
ATN+ GH L ++ P Q +D N + LK + G TI+W D
Sbjct: 1414 ATNKAGHNQCSGHLTVKEPPYFVEKPQSQD---VNPNTRVQLKALVGGTAPMTIKWFKDN 1470
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + + + L++ +AK +D G Y Q N +G T+ + V PP
Sbjct: 1471 KELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPP 1526
Score = 88.2 bits (209), Expect = 1e-16
Identities = 59/219 (26%), Positives = 99/219 (45%), Gaps = 5/219 (2%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
S+ QEPP FIK+LE ++ D+ + G P + W+KD+ EI S + ++
Sbjct: 3961 SAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMS 4020
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI 294
+S +VL H + D G+ C A N G A + L ++ P R + L
Sbjct: 4021 FVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK--- 4077
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
+ L+ + G P + W D + + + +I + + I + +D GEYQ +
Sbjct: 4078 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 4137
Query: 355 AKNIIGEDTAAFLVTVTAPPDPPRNVS-VTRQVDKSVTL 392
A N +G DT + + APP + +S ++ V K V L
Sbjct: 4138 ATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQL 4176
Score = 87.0 bits (206), Expect = 3e-16
Identities = 50/193 (25%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+ + A+ + VEF G P I WFKDD E+ S + I + STS
Sbjct: 1992 KEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSF 2051
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + + S G+ C TN G L + PK + ++ E + + ++ L+
Sbjct: 2052 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPK--FVKKLEASKIVKAGDSSRLE 2109
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P + W + H + D+ ++ +V+++++ D G++ +A+N G
Sbjct: 2110 CKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGS 2169
Query: 362 DTAAFLVTVTAPP 374
+ + V V PP
Sbjct: 2170 TSCSTKVIVKEPP 2182
Score = 86.6 bits (205), Expect = 4e-16
Identities = 54/198 (27%), Positives = 90/198 (45%), Gaps = 6/198 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTS 240
+EPP F+ +L +T + + E + G + W K+ E+ S IT E+ +
Sbjct: 2272 KEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVA 2331
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIF 299
L F + P++ G+ C N GG A L LE A + + + + ET
Sbjct: 2332 TLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIV----EKAGPMTVTVGETCT 2387
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ + G P ++EW DG + + + + S K S L+I S +R D G Y Q +N +
Sbjct: 2388 LECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 2447
Query: 360 GEDTAAFLVTVTAPPDPP 377
G+ + +V V+ PP
Sbjct: 2448 GKSSCTAVVDVSDRAVPP 2465
Score = 84.2 bits (199), Expect = 2e-15
Identities = 48/196 (24%), Positives = 88/196 (44%), Gaps = 3/196 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP F+KRL D + + T++G P +++W KD+Y I S R +IT E +++
Sbjct: 3589 KEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTI 3648
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + C N G + +A + + P P ++ + + I E L+
Sbjct: 3649 LEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAV---IGEPATLQ 3705
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P I W + + + ++ + L I+ SD GEY +A N +G
Sbjct: 3706 CKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGA 3765
Query: 362 DTAAFLVTVTAPPDPP 377
++ ++ + A PP
Sbjct: 3766 VASSAVLVIKARKLPP 3781
Score = 83.4 bits (197), Expect = 4e-15
Identities = 62/233 (26%), Positives = 99/233 (42%), Gaps = 8/233 (3%)
Query: 159 NDVGHSNYSELSDVL--TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTI 216
+DVG + ++V T S +EPP F+K+L D + L D VE G ++
Sbjct: 3188 SDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISV 3247
Query: 217 AWFKDDYEIF-SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC-L 274
W KD E+ S T I+ ++ + L S+ G+ C N G A L L
Sbjct: 3248 VWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 3307
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
E A + P + + L+ + G P + +W DG + D + I+ K
Sbjct: 3308 EPARIIEKP----EPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINK 3363
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
+ LKI A+ SD+G Y + KN +G+ V V+ PP + + V+
Sbjct: 3364 VASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVN 3416
Score = 82.2 bits (194), Expect = 9e-15
Identities = 52/208 (25%), Positives = 89/208 (42%), Gaps = 7/208 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP FIK++E ++L F T G T+ W KD EI +T + + +
Sbjct: 1148 REPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVAS 1207
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIF 299
L I +G+ C A N G A L ++ + E+ + ++ +
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATIT-----EEAVSIDVTQGDPAT 1262
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ G T +W DG + + +IS+T S+LKI S ++ D GEY + +N +
Sbjct: 1263 LQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDV 1322
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
G + + V PP +++D
Sbjct: 1323 GRSSCKARINVLDLIIPPSFTKKLKKMD 1350
Score = 81.8 bits (193), Expect = 1e-14
Identities = 58/235 (24%), Positives = 104/235 (44%), Gaps = 11/235 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++ LE + +A N GH+ + S LTV +EPP F+++ + N
Sbjct: 1397 LEISQLEGTDSGTYTCSATNKAGHN---QCSGHLTV------KEPPYFVEKPQSQDVNPN 1447
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
+V+ G TI WFKD+ E+ S ++ D++++ L +D G C
Sbjct: 1448 TRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQL 1507
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
+N G A +KA L ++ P ++ ++ L+ ++ + I G P + W DG+
Sbjct: 1508 SNDVGTATSKATLFVKEPP--QFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGN 1565
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I + IS + +I A+ + G Y +A+N G + + + V PP
Sbjct: 1566 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPP 1620
Score = 81.0 bits (191), Expect = 2e-14
Identities = 52/192 (27%), Positives = 83/192 (43%), Gaps = 1/192 (0%)
Query: 184 PPVFIKRL-EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
PP F KRL E V E + + +G T+AW+K++ EI + IT +T VL
Sbjct: 4913 PPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 4972
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ +D G C +N G A+ + + ++ K Q+ + E + L
Sbjct: 4973 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSC 5032
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G I+W G I DR S +VL++ ++D G+Y +A N+ G D
Sbjct: 5033 HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSD 5092
Query: 363 TAAFLVTVTAPP 374
T VT+ P
Sbjct: 5093 TTKSKVTIKDKP 5104
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/209 (23%), Positives = 85/209 (40%), Gaps = 3/209 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP F+K+++D+ AL V G ++ W K I + ++ +V
Sbjct: 586 KEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 645
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L+ + S G+ C A N G + L ++ K+ + + + + L+
Sbjct: 646 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII---ERAELIQVTAGDPATLE 702
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T+ G P +W DG P++ + IS + LK +SA+ D G+Y + N +G
Sbjct: 703 YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGS 762
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
+ TV P R VD V
Sbjct: 763 SSCETTFTVLDRDIAPFFTKPLRNVDSVV 791
Score = 79.8 bits (188), Expect = 5e-14
Identities = 66/228 (28%), Positives = 106/228 (46%), Gaps = 12/228 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLE-DVTALENDKVEFHV 206
H Q+ +A N +G ++ S LT R ++ P F IK + DV A E+ E HV
Sbjct: 2906 HSGQYSCSASNPLGTASSSAR---LTA---REPKKSPFFDIKPVSIDVIAGESADFECHV 2959
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
T G I W KD+ EI IT +T L ++ D G+ C ATN G
Sbjct: 2960 T--GAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKD 3017
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
+ A+L ++ PK + ++ E + + E+I L+ I G P + W + + +
Sbjct: 3018 MCSAQLSVKEPPK--FVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWK 3075
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+S ++L I+ A D G+Y +A N +G+ + + +TV APP
Sbjct: 3076 YNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPP 3123
Score = 79.8 bits (188), Expect = 5e-14
Identities = 52/206 (25%), Positives = 96/206 (46%), Gaps = 7/206 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EPP+F K+ + L+ V G P ++W+KD E+ S ++ I ++ +
Sbjct: 4061 KEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTS 4120
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ + +D GE +C ATN G + L+A P R+ ++ D + + + + L+
Sbjct: 4121 IHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAPP--RFVKKLSD-ISTVVGKEVQLQ 4177
Query: 302 TTIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
TTI G ++ W D I+ + D I IS + + L+ + ++ G+Y Q KN G
Sbjct: 4178 TTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAG 4237
Query: 361 EDTAAFLVTVTAPP---DPPRNVSVT 383
++V P + P ++ VT
Sbjct: 4238 MQECFATLSVLEPATIVEKPESIKVT 4263
Score = 79.8 bits (188), Expect = 5e-14
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 2/196 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP F+K+LE V D +G P ++W+K D ++ + + + + L
Sbjct: 4624 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 4683
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINETIFLK 301
+F+Q+ +D GE C A N G L + E + RQ D + + +
Sbjct: 4684 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRD-VQETVGLPVVFD 4742
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G ++ W DG P+ ++ S + L I RS G+Y A N IG
Sbjct: 4743 CAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGS 4802
Query: 362 DTAAFLVTVTAPPDPP 377
+++ + +T +PP
Sbjct: 4803 ASSSARLILTEGKNPP 4818
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/209 (23%), Positives = 84/209 (40%), Gaps = 3/209 (1%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A +EPP FIK++E+ T + F T +G P +I W KDD + I+ +S
Sbjct: 1708 ALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSV 1767
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
+ L + G C A N G A L ++ ++ + D + +
Sbjct: 1768 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVD---VTEKDPMT 1824
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L+ + G P ++W DG I+ +S + +I S + D G+Y + +N
Sbjct: 1825 LECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 1884
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
G + + V PP ++DK
Sbjct: 1885 GSSSCDAYLRVLDQNIPPSFTKKLTKMDK 1913
Score = 76.2 bits (179), Expect = 6e-13
Identities = 63/265 (23%), Positives = 99/265 (37%), Gaps = 8/265 (3%)
Query: 116 QVECNRLGS----TEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+++C GS W + I + +E + +ND G+ +
Sbjct: 796 RLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNS 855
Query: 172 VLTVSSDRAS--QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
V + S A QEPP F+ + L V TF G TI WFK + E+ S
Sbjct: 856 VGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGG 915
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
IT + S L + + SD G C +N G A L ++ + + E
Sbjct: 916 SCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK--EPATFVEKLEPS 973
Query: 290 LLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
L + + L + G P I W + I + +S +VL++ D G
Sbjct: 974 QLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSG 1033
Query: 350 EYQIQAKNIIGEDTAAFLVTVTAPP 374
EY +A+N G D + +V V P
Sbjct: 1034 EYMCEAQNEAGSDHCSSIVIVKESP 1058
Score = 76.2 bits (179), Expect = 6e-13
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 4/193 (2%)
Query: 183 EPPVFIKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP F+K+LE ++ D +G P + WF++++E+ +S + +T +S +V
Sbjct: 2086 EPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAV 2145
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ + + D G+ C A N G ++ ++ P + L N + L+
Sbjct: 2146 IQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLK---NAEVSLE 2202
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P + W D + + + +I+ + + I + SD GEY +A+N +G
Sbjct: 2203 CELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGS 2262
Query: 362 DTAAFLVTVTAPP 374
DT V + PP
Sbjct: 2263 DTCVCTVKLKEPP 2275
Score = 76.2 bits (179), Expect = 6e-13
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 6/195 (3%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP +++ E + D T +G P + WFKD E+ S + I+ S L
Sbjct: 4249 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 4308
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE---AAPKLRYPRQYEDGLLYEINETIF 299
+ PSD G N G A L + P + +GL ++
Sbjct: 4309 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS---GSSVV 4365
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++ + G P ++ W H+G+ I + + + ++T L ++ + SD G+Y A N+
Sbjct: 4366 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 4425
Query: 360 GEDTAAFLVTVTAPP 374
G D + +TV PP
Sbjct: 4426 GSDECSAPLTVREPP 4440
Score = 76.2 bits (179), Expect = 6e-13
Identities = 45/190 (23%), Positives = 77/190 (40%), Gaps = 3/190 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F ++L++ L V G P +++WF + EI S R+ T ++T L
Sbjct: 4346 PPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALT 4405
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ + SD G+ C ATN G A L + P Q D + + +
Sbjct: 4406 VNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSF---VQKPDPMDVLTGTNVTFTSI 4462
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P ++ W ++ DR +S+ + L++ S GEY N G+ +
Sbjct: 4463 VKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKAS 4522
Query: 364 AAFLVTVTAP 373
+ + AP
Sbjct: 4523 CTTHLYIKAP 4532
Score = 75.8 bits (178), Expect = 8e-13
Identities = 54/211 (25%), Positives = 88/211 (41%), Gaps = 5/211 (2%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
+ Y +S T++ A PP F+ R + +T +F T +G P W KD
Sbjct: 197 NEYGSVSCTATLTVTEAY--PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 254
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ S I+ E+ +L + D G C A+N+ G + +A L + P +
Sbjct: 255 ALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP--HFI 312
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA 343
++ E + IN+ + L+ + T+ W DG + +I K + L+I A
Sbjct: 313 KELEP-VQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLA 371
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
K D G Y A N G + + VTV PP
Sbjct: 372 KLKDSGTYVCTASNEAGSSSCSATVTVREPP 402
Score = 74.9 bits (176), Expect = 1e-12
Identities = 48/196 (24%), Positives = 84/196 (42%), Gaps = 2/196 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP F+ LE + A D V +G P T++W+K D ++ + + + L
Sbjct: 2742 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 2801
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINETIFLK 301
+F+++ +D GE C A N G A +K + E + RQ +D + + + L
Sbjct: 2802 VFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKD-IEQTVGLPVTLT 2860
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G + W DG + + ++ S + LKI S G+Y A N +G
Sbjct: 2861 CRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGT 2920
Query: 362 DTAAFLVTVTAPPDPP 377
+++ +T P P
Sbjct: 2921 ASSSARLTAREPKKSP 2936
Score = 74.9 bits (176), Expect = 1e-12
Identities = 57/242 (23%), Positives = 103/242 (42%), Gaps = 10/242 (4%)
Query: 158 LNDVGHSNYSELSDVLTVSSDRAS-------QEPPVFIKRLEDVTALENDKVEFHVTFSG 210
L DV S E + +++ + +AS + P F+KRL D + + + TF+G
Sbjct: 4499 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTG 4558
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P ++ W K+ + S+R ITT E + +L D G+ C N G A
Sbjct: 4559 TPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDSCSA 4618
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
++ + P + +Q E + + ++ L+ + G P + W + ++
Sbjct: 4619 QILILEPPY--FVKQLEP-VKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMH 4675
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
+ L + +D GEY +A+N +GE +A+ +TV PP R V ++V
Sbjct: 4676 FRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV 4735
Query: 391 TL 392
L
Sbjct: 4736 GL 4737
Score = 73.3 bits (172), Expect = 4e-12
Identities = 54/204 (26%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PPVF ++ V AL+ V SG P + W KD ++ +S++ IT+ + L
Sbjct: 3122 PPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLH 3181
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ SD GE C ATN G + + P R+ ++ D I + + L+
Sbjct: 3182 ILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP--RFVKKLSDTSTL-IGDAVELRAI 3238
Query: 304 IVGKPTPTIEWRHD-GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G ++ W D G I + IS + L++ S + S+ G+Y Q KN G
Sbjct: 3239 VEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMR 3298
Query: 363 TAAFLVTVTAPP---DPPRNVSVT 383
+ ++TV P + P ++VT
Sbjct: 3299 ECSAVLTVLEPARIIEKPEPMTVT 3322
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/192 (25%), Positives = 78/192 (40%), Gaps = 3/192 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+E P F K + + L+ V +G P I WFKD+ + S R+ +
Sbjct: 1055 KESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVS 1114
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + + +D GE +C TN G ++ AR+ L P + L T +
Sbjct: 1115 LQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLR---GGTAAFQ 1171
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
T+ G T+ W D I DD I ++ + L + + G+Y QAKN G
Sbjct: 1172 ATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGI 1231
Query: 362 DTAAFLVTVTAP 373
+ L++V P
Sbjct: 1232 QRCSALLSVKEP 1243
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/211 (22%), Positives = 86/211 (40%), Gaps = 3/211 (1%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP F+KRL D + + T++G ++ W KD + I +S + I T E T +
Sbjct: 2648 KEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCI 2707
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L D G+ C N G V A + P + + E L + +++ L+
Sbjct: 2708 LEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPY--FVTELEP-LEAAVGDSVSLQ 2764
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P T+ W + T + L + +D GEY +A+N IG
Sbjct: 2765 CQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGT 2824
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
++ + + PP + ++++V L
Sbjct: 2825 ASSKTVFRIQERQLPPSFARQLKDIEQTVGL 2855
Score = 72.1 bits (169), Expect = 1e-11
Identities = 61/234 (26%), Positives = 102/234 (43%), Gaps = 12/234 (5%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L +T ++ + A+NDVG SD + S++ +EPP FIK LE +
Sbjct: 460 LDITDVKVEDSGSYSCEAVNDVG-------SD--SCSTEIVIKEPPSFIKTLEPADIVRG 510
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
SG I+WFKD +I SS++ + + +S L +D GE +C
Sbjct: 511 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 570
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G A L+ P + ++ +D L+ +T+ L+ + G ++ W
Sbjct: 571 ANEVGKCGCMATHLLKEPP--TFVKKVDD-LIALGGQTVTLQAAVRGSEPISVTWMKGQE 627
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
I D +I++S + +VL I + S G+Y A+N G T+ + V P
Sbjct: 628 VIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEP 681
Score = 72.1 bits (169), Expect = 1e-11
Identities = 54/219 (24%), Positives = 98/219 (44%), Gaps = 6/219 (2%)
Query: 167 SELSDVLTVSSDRASQEPPVFIKRLEDVTALEN-DKVEFHVTFSGIPSPTIAWFKDDYEI 225
S ++ + S++ +EP F+++LE L+ D + +G P I WF +D EI
Sbjct: 946 SNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREI 1005
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S + ++ EST+VL + D GE C A N G + + ++ +P + ++
Sbjct: 1006 KESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY--FTKE 1063
Query: 286 YED-GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAK 344
++ +L E + + L + G P I W D + + + + I L+I
Sbjct: 1064 FKPIEVLKEYD--VMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFV 1121
Query: 345 RSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+D GEYQ + N +G + VT+ PP + + T
Sbjct: 1122 AADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIEST 1160
Score = 71.7 bits (168), Expect = 1e-11
Identities = 60/238 (25%), Positives = 91/238 (38%), Gaps = 15/238 (6%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L L+G+E H ++ A ND G S L V +EP + + +
Sbjct: 1208 LYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV---------KEPATITEEAVSIDVTQG 1258
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
D V FSG T WFKD E+ + I+ ++ S+L D GE
Sbjct: 1259 DPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEV 1318
Query: 260 TNRGGHAVTKAR---LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
N G + KAR L L P + D + I L+ + G +I+W
Sbjct: 1319 QNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIK---GSFIDLECIVAGSHPISIQWFK 1375
Query: 317 DGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D I ++ + S + L+I + +D G Y A N G + + +TV PP
Sbjct: 1376 DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPP 1433
Score = 70.5 bits (165), Expect = 3e-11
Identities = 58/228 (25%), Positives = 102/228 (44%), Gaps = 12/228 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF-IKRLE-DVTALENDKVEFHV 206
H Q+ +A N +G ++ S + S+ + PP F +K + D+ E+ + HV
Sbjct: 3847 HIGQYNCSASNPLGTAS----SSAKLILSEH--EVPPFFDLKPVSVDLALGESGTFKCHV 3900
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
T G I W KD+ EI +T E+T+ L ++ D G+ C A+N G
Sbjct: 3901 T--GTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD 3958
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A+L ++ P R+ ++ E + + +E + I G P + W D I +
Sbjct: 3959 SCSAQLGVQEPP--RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSK 4016
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+S +VL++H+ D G+Y +A N G +++ + V PP
Sbjct: 4017 FRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 4064
Score = 69.7 bits (163), Expect = 5e-11
Identities = 57/240 (23%), Positives = 97/240 (40%), Gaps = 8/240 (3%)
Query: 126 EWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRA----- 180
+W + P+V + ++ + +F A L+D G + ++V + S +
Sbjct: 714 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 773
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
P F K L +V ++ N +G ++WFKD EI +S R I E T+
Sbjct: 774 RDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTA 833
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ +D G C ATN G + L ++ P +D L + L
Sbjct: 834 SLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVL---PGSAVCL 890
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K+T G TI W +++ I+ S L+++ K SD G Y + N+ G
Sbjct: 891 KSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAG 950
Score = 69.3 bits (162), Expect = 7e-11
Identities = 71/304 (23%), Positives = 119/304 (39%), Gaps = 19/304 (6%)
Query: 81 GKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE----WIRTAPPIVL 136
G + +L+ EP I K P T G P + +EC G+ E W + +
Sbjct: 3296 GMRECSAVLTVLEPARIIEKPEPMTVTTGNP---FALECVVTGTPELSAKWFKDGRELSA 3352
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDV----LTVS---SDRASQEPPVFIK 189
+ +T + + A ++D G ++ + V TVS SDR PP FI+
Sbjct: 3353 DSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIV--PPSFIR 3410
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
+L+DV A+ V SG ++ WF+D EI S + + E+ L + P
Sbjct: 3411 KLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEP 3470
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
SD G C A N G A L ++ P Q D + ++ + I G P
Sbjct: 3471 SDTGIYTCVAANVAGSDECSAVLTVQEPPSF---EQTPDSVEVLPGMSLTFTSVIRGTPP 3527
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
++W ++ + IS+ + L++ + + G+Y N G + +
Sbjct: 3528 FKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 3587
Query: 370 VTAP 373
V P
Sbjct: 3588 VKEP 3591
Score = 68.5 bits (160), Expect = 1e-10
Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 2/192 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+ P FIK LE V + N KV T+ W KD ++ + I ++ + L
Sbjct: 307 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 366
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G CTA+N G + A + + P + ++ + L E+ L
Sbjct: 367 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS--FVKKVDPSYLMLPGESARLHC 424
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ G P + W + + + + + ++L I K D G Y +A N +G D
Sbjct: 425 KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSD 484
Query: 363 TAAFLVTVTAPP 374
+ + + + PP
Sbjct: 485 SCSTEIVIKEPP 496
Score = 67.7 bits (158), Expect = 2e-10
Identities = 49/198 (24%), Positives = 91/198 (45%), Gaps = 6/198 (3%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP FI+ LE V A+ + G P I+W+K+ ++ S+ + + + L
Sbjct: 3683 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3742
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR--YPRQYEDGLLYE-INETIF 299
+ +++ SD GE C A N G + A L ++A KL + R+ +D ++E + +
Sbjct: 3743 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKAR-KLPPFFARKLKD--VHETLGFPVA 3799
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ I G + W DG + D ++ S + L+I +S G+Y A N +
Sbjct: 3800 FECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPL 3859
Query: 360 GEDTAAFLVTVTAPPDPP 377
G +++ + ++ PP
Sbjct: 3860 GTASSSAKLILSEHEVPP 3877
Score = 67.7 bits (158), Expect = 2e-10
Identities = 60/242 (24%), Positives = 100/242 (41%), Gaps = 14/242 (5%)
Query: 147 PPHKYQFR--VAAL--NDVGHSNYSELS-----DVLTVSSD-----RASQEPPVFIKRLE 192
P +K QF+ VA+L N V HS+ E S V V+S +A + PP F ++L+
Sbjct: 3729 PAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLK 3788
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV V F +G ++W+KD + + + + L Q S
Sbjct: 3789 DVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHI 3848
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C+A+N G A + A+L L + + + E+ K + G I
Sbjct: 3849 GQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKI 3908
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W D I ++++ + L + + D G+Y A NI G+D+ + + V
Sbjct: 3909 TWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE 3968
Query: 373 PP 374
PP
Sbjct: 3969 PP 3970
Score = 66.5 bits (155), Expect = 5e-10
Identities = 61/228 (26%), Positives = 98/228 (42%), Gaps = 18/228 (7%)
Query: 152 QFRVAALNDVGHSNYSELSDV---LTVSSD--RASQEPPVFIKRLEDVTALENDKVEFHV 206
Q R A +ND G +D L SS + ++PPVF + L VT E + V+
Sbjct: 4973 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSC 5032
Query: 207 TFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G I W K EI S R + + T+VL + +D G+ C A+N G
Sbjct: 5033 HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSD 5092
Query: 267 VTKARLCLEAAPKL--RYPRQYEDGLLYEINE----TIFLKTT------IVGKPTPTIEW 314
TK+++ ++ P + + DG L+ ++E + KTT + G P P ++W
Sbjct: 5093 TTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKW 5152
Query: 315 -RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ + R+ I + L+I ++D G Y+ A N GE
Sbjct: 5153 TKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 5200
Score = 66.1 bits (154), Expect = 6e-10
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 6/196 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+EP I+R E + D T +G P W+KD + +S++ I+ + +
Sbjct: 679 KEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQ 738
Query: 242 LLFHQILPSDEGEIKCTATNRGGHA---VTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
L F+ D G+ +N G + T L + AP P + D + +N T
Sbjct: 739 LKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSV---VNGTC 795
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
L I G + W DG I DR I+ + L+I +D G + +A N
Sbjct: 796 RLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNS 855
Query: 359 IGEDTAAFLVTVTAPP 374
+G ++ + V PP
Sbjct: 856 VGSKDSSGALIVQEPP 871
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/228 (23%), Positives = 100/228 (43%), Gaps = 11/228 (4%)
Query: 168 ELSDVLTVSSDRAS---QEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWFKDDY 223
+LS+ + ++ +A+ +EPP FIK+ V L N + F +G P ++W+ D
Sbjct: 1506 QLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGN 1565
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
EI + ++ I+ + + + G C A N G A L ++ P +
Sbjct: 1566 EITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPT--FI 1623
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSA 343
R+ + + + ++ + L+ + G P + W + I + + ++T + SV +H
Sbjct: 1624 RELKPVEVVKYSD-VELECEVTGTPPFEVTWLKNNREIRSSKKY--TLTDRVSVFNLHIT 1680
Query: 344 K--RSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKS 389
K SD GEYQ N G + + V + PP + + T V KS
Sbjct: 1681 KCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKS 1728
Score = 64.1 bits (149), Expect = 3e-09
Identities = 52/227 (22%), Positives = 91/227 (40%), Gaps = 7/227 (3%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A N +G ++ S +LT + PP F RL V A+ + +F +G
Sbjct: 4791 QYSCTATNPIGSAS-SSARLILT-----EGKNPPFFDIRLAPVDAVVGESADFECHVTGT 4844
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
++W KD EI S + I+ E+++ L ++ D G+ C A N G A+
Sbjct: 4845 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQ 4904
Query: 272 LCL-EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
L + E + ++ + + + L+ + G T+ W + I EI+
Sbjct: 4905 LNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEIT 4964
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPP 377
VL++ A +D G Y + N G + + P PP
Sbjct: 4965 FKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 5011
Score = 63.7 bits (148), Expect = 3e-09
Identities = 61/262 (23%), Positives = 107/262 (40%), Gaps = 12/262 (4%)
Query: 116 QVECNRLGSTE----WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSEL 169
++EC GS E W R + + +T ++ Q + D G
Sbjct: 2107 RLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNP 2166
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
+ + S+ +EPPVF V L+N +V SG P + W+KD ++ SS+
Sbjct: 2167 AGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSK 2226
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ I + + + + SD GE C A N G + L+ P R+ + +
Sbjct: 2227 KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP--RFVSKL-NS 2283
Query: 290 LLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDR 348
L E L+ +I G ++W + +I + + I I+ + L+ A+ ++
Sbjct: 2284 LTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANA 2343
Query: 349 GEYQIQAKNIIG--EDTAAFLV 368
G+Y Q KN G E+ A +V
Sbjct: 2344 GKYICQIKNDGGMRENMATLMV 2365
Score = 63.3 bits (147), Expect = 5e-09
Identities = 40/196 (20%), Positives = 80/196 (40%), Gaps = 6/196 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
QEP +++ + V E D + +G P + W KD +I SR +++ + + +
Sbjct: 1803 QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 1862
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL---EAAPKLRYPRQYEDGLLYEINETI 298
++ D G+ N G + A L + P D +L +I
Sbjct: 1863 FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL---GSSI 1919
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
++ + G + +W DG I T + + + L++++ + D Y + N+
Sbjct: 1920 HMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNV 1979
Query: 359 IGEDTAAFLVTVTAPP 374
G+D + ++TV PP
Sbjct: 1980 AGDDACSGILTVKEPP 1995
Score = 60.9 bits (141), Expect = 2e-08
Identities = 53/217 (24%), Positives = 83/217 (38%), Gaps = 4/217 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV +++E + +F P+ WFK EI+ S + +I + + S L
Sbjct: 121 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 180
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D GE C A+N G A L + EA P R L + + T
Sbjct: 181 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSR--PKSLTTFVGKAAKFICT 238
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P W+ DG + IS +L++ + DRG Y +A N G D
Sbjct: 239 VTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADI 298
Query: 364 A-AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPAD 399
A L+ + P V ++K V L+ + D
Sbjct: 299 CQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDED 335
Score = 60.1 bits (139), Expect = 4e-08
Identities = 51/248 (20%), Positives = 93/248 (37%), Gaps = 5/248 (2%)
Query: 153 FRVAALNDVGHSNYSELSDVLTVSSD-----RASQEPPVFIKRLEDVTALENDKVEFHVT 207
F +ND G + + T SS + Q PP F ++L+D+ V
Sbjct: 2803 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCR 2862
Query: 208 FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV 267
+G + W++D + + ++ + L Q S G+ C+A+N G A
Sbjct: 2863 LNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTAS 2922
Query: 268 TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
+ ARL K + + E+ + + G I W D I
Sbjct: 2923 SSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNY 2982
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
I+ L+I + D G+Y QA N +G+D + ++V PP + + ++
Sbjct: 2983 TITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAK 3042
Query: 388 KSVTLDWE 395
+ ++ E
Sbjct: 3043 QGESIQLE 3050
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/194 (21%), Positives = 78/194 (40%), Gaps = 4/194 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP V +++ +T + +G P ++ W+KD + SS++ + S L
Sbjct: 2367 EPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSL 2426
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIFL 300
+ D G N G + A + + A P R G + + + L
Sbjct: 2427 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGV--LGASCIL 2484
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G ++ W H+ I++ + + + + L+++S SD G Y A N+ G
Sbjct: 2485 ECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAG 2544
Query: 361 EDTAAFLVTVTAPP 374
D ++TV PP
Sbjct: 2545 SDECRAVLTVQEPP 2558
Score = 58.8 bits (136), Expect = 1e-07
Identities = 52/219 (23%), Positives = 91/219 (41%), Gaps = 15/219 (6%)
Query: 159 NDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
ND G E S VLTV EP I++ E +T + +G P + W
Sbjct: 3293 NDAG---MRECSAVLTVL------EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKW 3343
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
FKD E+ + + IT + L SD+G N G + + + +
Sbjct: 3344 FKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKS--NCTVSVHVSD 3401
Query: 279 KLRYP---RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
++ P R+ +D + + ++ L+ + G ++ W DG+ I++ + + S +
Sbjct: 3402 RIVPPSFIRKLKD-VNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENV 3460
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
L + + SD G Y A N+ G D + ++TV PP
Sbjct: 3461 CTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPP 3499
Score = 58.0 bits (134), Expect = 2e-07
Identities = 57/210 (27%), Positives = 76/210 (36%), Gaps = 21/210 (10%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP I L+D E F SG ++W+ D +I SR +T E T L
Sbjct: 9 PPAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLE 67
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK-- 301
+ P DEG A N G + A L LEA + + R E + E+ +K
Sbjct: 68 IAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHER-IEQEIEMEMKAAPVIKRK 126
Query: 302 ---------------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS 346
I P +W G I D+ I + S L+I +
Sbjct: 127 IEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVV 186
Query: 347 DRGEYQIQAKNIIG--EDTAAFLVTVTAPP 374
D GEY +A N G TA VT PP
Sbjct: 187 DCGEYTCKASNEYGSVSCTATLTVTEAYPP 216
Score = 47.2 bits (107), Expect = 3e-04
Identities = 50/235 (21%), Positives = 92/235 (39%), Gaps = 13/235 (5%)
Query: 168 ELSDVLTVSSDRASQ-EPPVFIKRLEDVTALENDKVEFHVTFS-GIPSPTIAWFKDDYEI 225
E ++++ R SQ EP IK +E+ T L+++ F + P ++W+K ++
Sbjct: 5303 EFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKL 5362
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S + I+ D L D+G + G H + +E A + R
Sbjct: 5363 EPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC---GPHIASAKLTVIEPA----WERH 5415
Query: 286 YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
+D L E +T + T P EW +G + R + + K L I +
Sbjct: 5416 LQDVTLKE-GQTCTM-TVQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRA 5473
Query: 346 SDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
D+G+Y + +++ E +A + R ++ +S T + E DD
Sbjct: 5474 EDQGQYTCKYEDL--ETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDD 5526
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 6/131 (4%)
Query: 125 TEWIRTAPPIVLRPELVLTGLEPPHK-YQFRVAALNDVGHSNYS-ELSDVLTVSSDRASQ 182
+EW R +L+P+ E HK ++ +A + Y+ + D+ T + R
Sbjct: 5440 SEWFRNGR--ILKPQ-GRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEA 5496
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP F KR++++ E+ F S + W+K E+ S++ D +
Sbjct: 5497 EPIQFTKRIQNIVVSEHQSATFECEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYM 5555
Query: 243 LFHQILPSDEG 253
H + P DEG
Sbjct: 5556 TIHNVTPDDEG 5566
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 6/142 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA---WFKDDYEIFSSRRTAITTDESTS 240
P F+K ++D+ E++ V F + SP+ A W KD I S + D
Sbjct: 7801 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDR 7860
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + SD GE C + A+L +E P +R+ + E+ + + ++L
Sbjct: 7861 KLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP-VRFVKTLEEEVTVVKGQPLYL 7919
Query: 301 KTTIVGKPTPTIEWRHDGHPII 322
+ + WR DG ++
Sbjct: 7920 SCEL--NKERDVVWRKDGKIVV 7939
Score = 32.7 bits (71), Expect = 7.3
Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 8/102 (7%)
Query: 758 EKDEFSESQTLKPLPDPNFVPKPILKRREIPEQSPAQNLMPPKSFVSAPKTEAKRQ-EKL 816
E ++ E LKP P P P P + ++ E+ +P K P+ K + L
Sbjct: 7554 EPEKVIEKPKLKPRPPP---PPPAPPKEDVKEKIFQLKAIPKKKVPENPQVPEKVELTPL 7610
Query: 817 TL---FKKITKM-PVQKPFNFPKILSKNSMNKKQNTSEPEIE 854
+ KK+ K+ P +KP +++ K+ + K+ EP++E
Sbjct: 7611 KVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 7652
>BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein.
Length = 867
Score = 94.3 bits (224), Expect = 2e-18
Identities = 93/381 (24%), Positives = 153/381 (40%), Gaps = 26/381 (6%)
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
EL++ + ++ V A+ D + Y + ++TV A+ + + DV A
Sbjct: 474 ELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTA-IVTVEERLATVK-----SGMSDVHAAT 527
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCT 258
E V + + W KD EI I + L+F + P EG+
Sbjct: 528 GSPAELCVVLNDEKVEGV-WLKDGKEITDLPGVQIVKQGAVHKLIFPSMGPEHEGKY--- 583
Query: 259 ATNRGGHAVTKARLCLEAAPKLRYPRQYE----DGLLYEINETIFLKTTIVGKPTPTIEW 314
T R ++A + + P + P E + ++ T +K GKP P + W
Sbjct: 584 -TFRAKGTESEASVFIADPPTID-PSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTW 641
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
DG + ++R+ + ++L I + R D G ++ KN G TA ++V P
Sbjct: 642 YKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRP 701
Query: 375 DPPR-NVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK--AITSRKTNV 431
PP+ V V + W+ P D+GG V +IVE G W+K + + TN
Sbjct: 702 KPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNF 761
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSS-----ESSPVRIPGRAIDMDFLAV--EARIIN 484
+ + EG Y+FRI A + G+S P +P+ PG A V EA I
Sbjct: 762 STNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
Query: 485 EALTREDGEEPRISPAPRRKR 505
+DG P + R++
Sbjct: 822 WNAPTQDGGAPVLGYIVERRK 842
Score = 63.3 bits (147), Expect = 5e-09
Identities = 62/240 (25%), Positives = 89/240 (37%), Gaps = 19/240 (7%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T V F G P P + W+KD E+ R ++ E ++L + D G
Sbjct: 617 ITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSG 676
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV----GKPT 309
I N G A L + PK P Q L + +K G+P
Sbjct: 677 LILLKLKNDHGSATATLHLSVLDRPK---PPQGRVEFLELSGSCVHMKWKAPKDNGGRPV 733
Query: 310 PT--IEWRHDGHPI-ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-----E 361
+E R G I ++ +T FS K+ K +++I A N G E
Sbjct: 734 TQFIVERRAVGKKSWIKIGEVDGKVT-NFSTNKVEEGKAY---QFRILAVNSEGVSDPLE 789
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWL 421
F PP VT ++VT+ W P DGG V YIVE + G N+W+
Sbjct: 790 TEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
Score = 47.2 bits (107), Expect = 3e-04
Identities = 48/200 (24%), Positives = 82/200 (41%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
+ND G + S + D + EP F+ ++ V E F + S P
Sbjct: 302 MNDAGIYSLS-VGDKRMSAELTVLDEPLKFLGEMKPVKVTERQTAVFEIRLSK-KEPNFV 359
Query: 218 WFKDDYEIFSSRRTAITTDES--TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
W + E+ + IT E T L SD GE A G+ V KA+L ++
Sbjct: 360 WKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEA----GNLVQKAQLTID 415
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P +++ ++ + E + L+ + K T+ W+ DG ++ + ++ K
Sbjct: 416 RIP-IKFVSNLKNVRVKERSRAC-LECELTSKDV-TLRWKKDGQLLMHGTKYSMNHEGKQ 472
Query: 336 SVLKIHSAKRSDRGEYQIQA 355
+ L I A+ SD GEY + A
Sbjct: 473 AELIIEDAQLSDGGEYTVVA 492
Score = 46.8 bits (106), Expect = 4e-04
Identities = 34/124 (27%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 164 SNYSELSDVLTVSSD-RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD 222
S+ E ++T SS+ A P F+++ + VTA E DK F G P P I+W ++
Sbjct: 45 SSIVEFFSLVTRSSNIPAGDSVPEFVEKPQPVTAPEGDKAVFRARVQGNPKPHISWKRES 104
Query: 223 -YEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV-TKARLCLEAAPKL 280
I S + + VL + D KC A+N A+ T + L E K+
Sbjct: 105 GIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCIASNDHADAIYTVSLLVTEGQEKM 164
Query: 281 RYPR 284
+ +
Sbjct: 165 DFKK 168
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/55 (40%), Positives = 29/55 (52%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI 128
AG P P P ++D A+T+ W T DGGAP+ GY VE + GS W+
Sbjct: 795 AGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWV 849
Score = 43.2 bits (97), Expect = 0.005
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 11/130 (8%)
Query: 69 VHWKSAGRPAPP-GKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW 127
+H RP PP G+ + + + + + +KW +GG P+ + VE +G W
Sbjct: 693 LHLSVLDRPKPPQGRVEFLELSG----SCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSW 748
Query: 128 IRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVF 187
I+ +E YQFR+ A+N G S+ E +V + EPP F
Sbjct: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGN----PIEPPGF 804
Query: 188 IK--RLEDVT 195
++ DVT
Sbjct: 805 ASQPQVTDVT 814
Score = 38.7 bits (86), Expect = 0.11
Identities = 18/57 (31%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNII 359
+ K P W+ +G + DD+ EI+++ LKI A+ SD GE+ +A N++
Sbjct: 351 LSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLV 407
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 91.5 bits (217), Expect = 1e-17
Identities = 84/302 (27%), Positives = 138/302 (45%), Gaps = 26/302 (8%)
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSVLL 243
VF+K+ + + V SG+P+PTI W K++ + SS R + S +
Sbjct: 250 VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEI-- 307
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D G C A N +A L ++A P+ + +Q + +E + +F +
Sbjct: 308 -SDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPE--FLKQPTNIYAHESMDIVF-ECE 363
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--E 361
+ GKPTPT++W +G +I D +I K L++ +SD G YQ A+N +G +
Sbjct: 364 VTGKPTPTVKWVKNGDMVIPSDYFKI---VKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Query: 362 DTAAFLVTVTAP------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
A ++ AP P PR+V + + + L W PA D Y V Y +
Sbjct: 421 AGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKE 480
Query: 416 GWNVWLKAITSR--KTNVTLFDLIEGSEYKFRIKAESPYG---MSAP-SSESSP-VRIPG 468
G TS + VT+ +L+ + Y FR+ A++ +G SAP E+ P V++PG
Sbjct: 481 GIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPG 540
Query: 469 RA 470
A
Sbjct: 541 PA 542
Score = 68.5 bits (160), Expect = 1e-10
Identities = 73/299 (24%), Positives = 133/299 (44%), Gaps = 23/299 (7%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
++ + ++ Q P F+K+ ++ A E+ + F +G P+PT+ W K+ + S
Sbjct: 326 NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD 385
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL-CLEAAPKLRYP-RQYE 287
I + + VL ++ SDEG +C A N G+A A+L LE AP P
Sbjct: 386 YFKIVKEHNLQVL---GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAP 442
Query: 288 DGLLYEINETIFLK---TTIVGKP-----TPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
++ + T F+K T P T ++ + +G I +R+E + P +
Sbjct: 443 RDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEG---IARERVENTSHPGEMQVT 499
Query: 340 IHSAKRSDRGEYQIQAKNIIGE-DTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDW 394
I + + +++ A+N G +++A L T P P P N+ S+T+ W
Sbjct: 500 IQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTW 559
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
E P G ++ NY + Y G + + + + T+ L + +EY FR+ A + +G
Sbjct: 560 ETPVSGNG-EIQNYKLYYMEKGTDK-EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 47.2 bits (107), Expect = 3e-04
Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 12/175 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSV 241
P F+ D ++ V + + PSP I W KD + S R + D S +
Sbjct: 52 PFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 242 --LLFHQILPSDEGEIKCTATNRG-GHAVTK-ARLCLEAAPKLRYPRQYEDGLLYEINET 297
++ + DEG +C AT G +++ A+L + P R+ Q E +Y N
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP--RFTSQPEPSSVYAGNNA 169
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L + P + W + P++ DDR+ I +L I +A D G Y+
Sbjct: 170 I-LNCEVNADLVPFVRWEQNRQPLLLDDRV---IKLPSGMLVISNATEGDGGLYR 220
Score = 46.8 bits (106), Expect = 4e-04
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 10/102 (9%)
Query: 373 PPDPPRNVSVTRQVDKSVTL--DWEPPADDGGCKVGNYIVEYYRTGWNV----W-LKAIT 425
P PP++V+V + K T+ +W+PP++ G K+ YI+ YY T N W ++ +
Sbjct: 954 PTSPPKDVTVVSKEGKPKTIIVNWQPPSEANG-KITGYII-YYSTDVNAEIHDWVIEPVV 1011
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
+ + +L + Y F+I+A + GM P SE+ R P
Sbjct: 1012 GNRLTHQIQELTLDTPYYFKIQARNSKGM-GPMSEAVQFRTP 1052
Score = 35.9 bits (79), Expect = 0.78
Identities = 46/234 (19%), Positives = 92/234 (39%), Gaps = 11/234 (4%)
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
E + R T+ + ++P+ + A N+ G + A L +E P+++ P
Sbjct: 480 EGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLP 539
Query: 284 RQYEDGLLYEINETIFLKT--TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIH 341
+ Y + T T T V ++ TD ++ ++ I+
Sbjct: 540 GPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYT--IN 597
Query: 342 SAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPP 397
K+ +++ A N G + V V P P+N+S+ + KS+ + W+PP
Sbjct: 598 GLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 398 AD-DGGCKVGNYIVEYYRTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKA 448
A ++ Y + Y + +V ++ + + + L G+EY FR+ A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAA 711
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 91.5 bits (217), Expect = 1e-17
Identities = 84/302 (27%), Positives = 138/302 (45%), Gaps = 26/302 (8%)
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSVLL 243
VF+K+ + + V SG+P+PTI W K++ + SS R + S +
Sbjct: 250 VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEI-- 307
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D G C A N +A L ++A P+ + +Q + +E + +F +
Sbjct: 308 -SDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPE--FLKQPTNIYAHESMDIVF-ECE 363
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--E 361
+ GKPTPT++W +G +I D +I K L++ +SD G YQ A+N +G +
Sbjct: 364 VTGKPTPTVKWVKNGDMVIPSDYFKI---VKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Query: 362 DTAAFLVTVTAP------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
A ++ AP P PR+V + + + L W PA D Y V Y +
Sbjct: 421 AGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKE 480
Query: 416 GWNVWLKAITSR--KTNVTLFDLIEGSEYKFRIKAESPYG---MSAP-SSESSP-VRIPG 468
G TS + VT+ +L+ + Y FR+ A++ +G SAP E+ P V++PG
Sbjct: 481 GIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPG 540
Query: 469 RA 470
A
Sbjct: 541 PA 542
Score = 68.5 bits (160), Expect = 1e-10
Identities = 73/299 (24%), Positives = 133/299 (44%), Gaps = 23/299 (7%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
++ + ++ Q P F+K+ ++ A E+ + F +G P+PT+ W K+ + S
Sbjct: 326 NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD 385
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL-CLEAAPKLRYP-RQYE 287
I + + VL ++ SDEG +C A N G+A A+L LE AP P
Sbjct: 386 YFKIVKEHNLQVL---GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAP 442
Query: 288 DGLLYEINETIFLK---TTIVGKP-----TPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
++ + T F+K T P T ++ + +G I +R+E + P +
Sbjct: 443 RDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEG---IARERVENTSHPGEMQVT 499
Query: 340 IHSAKRSDRGEYQIQAKNIIGE-DTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDW 394
I + + +++ A+N G +++A L T P P P N+ S+T+ W
Sbjct: 500 IQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTW 559
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
E P G ++ NY + Y G + + + + T+ L + +EY FR+ A + +G
Sbjct: 560 ETPVSGNG-EIQNYKLYYMEKGTDK-EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 46.8 bits (106), Expect = 4e-04
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 10/102 (9%)
Query: 373 PPDPPRNVSVTRQVDKSVTL--DWEPPADDGGCKVGNYIVEYYRTGWNV----W-LKAIT 425
P PP++V+V + K T+ +W+PP++ G K+ YI+ YY T N W ++ +
Sbjct: 954 PTSPPKDVTVVSKEGKPKTIIVNWQPPSEANG-KITGYII-YYSTDVNAEIHDWVIEPVV 1011
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
+ + +L + Y F+I+A + GM P SE+ R P
Sbjct: 1012 GNRLTHQIQELTLDTPYYFKIQARNSKGM-GPMSEAVQFRTP 1052
Score = 46.4 bits (105), Expect = 6e-04
Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 12/175 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSV 241
P F+ D ++ V + + PSP I W KD + S R + D S +
Sbjct: 52 PFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 242 --LLFHQILPSDEGEIKCTATNRG-GHAVTK-ARLCLEAAPKLRYPRQYEDGLLYEINET 297
++ + DEG +C AT G +++ A+L + P R+ Q E +Y N
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP--RFTSQPEPSSVYAGNGA 169
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L + P + W + P++ DDR+ I +L I +A D G Y+
Sbjct: 170 I-LNCEVNADLVPFVRWEQNRQPLLLDDRV---IKLPSGMLVISNATEGDGGLYR 220
Score = 35.9 bits (79), Expect = 0.78
Identities = 46/234 (19%), Positives = 92/234 (39%), Gaps = 11/234 (4%)
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
E + R T+ + ++P+ + A N+ G + A L +E P+++ P
Sbjct: 480 EGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLP 539
Query: 284 RQYEDGLLYEINETIFLKT--TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIH 341
+ Y + T T T V ++ TD ++ ++ I+
Sbjct: 540 GPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYT--IN 597
Query: 342 SAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPP 397
K+ +++ A N G + V V P P+N+S+ + KS+ + W+PP
Sbjct: 598 GLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 398 AD-DGGCKVGNYIVEYYRTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKA 448
A ++ Y + Y + +V ++ + + + L G+EY FR+ A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAA 711
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 91.5 bits (217), Expect = 1e-17
Identities = 84/302 (27%), Positives = 138/302 (45%), Gaps = 26/302 (8%)
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSVLL 243
VF+K+ + + V SG+P+PTI W K++ + SS R + S +
Sbjct: 250 VFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEI-- 307
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D G C A N +A L ++A P+ + +Q + +E + +F +
Sbjct: 308 -SDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPE--FLKQPTNIYAHESMDIVF-ECE 363
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--E 361
+ GKPTPT++W +G +I D +I K L++ +SD G YQ A+N +G +
Sbjct: 364 VTGKPTPTVKWVKNGDMVIPSDYFKI---VKEHNLQVLGLVKSDEGFYQCIAENDVGNAQ 420
Query: 362 DTAAFLVTVTAP------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
A ++ AP P PR+V + + + L W PA D Y V Y +
Sbjct: 421 AGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKE 480
Query: 416 GWNVWLKAITSR--KTNVTLFDLIEGSEYKFRIKAESPYG---MSAP-SSESSP-VRIPG 468
G TS + VT+ +L+ + Y FR+ A++ +G SAP E+ P V++PG
Sbjct: 481 GIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPG 540
Query: 469 RA 470
A
Sbjct: 541 PA 542
Score = 68.5 bits (160), Expect = 1e-10
Identities = 73/299 (24%), Positives = 133/299 (44%), Gaps = 23/299 (7%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR 229
++ + ++ Q P F+K+ ++ A E+ + F +G P+PT+ W K+ + S
Sbjct: 326 NETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD 385
Query: 230 RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL-CLEAAPKLRYP-RQYE 287
I + + VL ++ SDEG +C A N G+A A+L LE AP P
Sbjct: 386 YFKIVKEHNLQVL---GLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAP 442
Query: 288 DGLLYEINETIFLK---TTIVGKP-----TPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
++ + T F+K T P T ++ + +G I +R+E + P +
Sbjct: 443 RDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEG---IARERVENTSHPGEMQVT 499
Query: 340 IHSAKRSDRGEYQIQAKNIIGE-DTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDW 394
I + + +++ A+N G +++A L T P P P N+ S+T+ W
Sbjct: 500 IQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTW 559
Query: 395 EPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
E P G ++ NY + Y G + + + + T+ L + +EY FR+ A + +G
Sbjct: 560 ETPVSGNG-EIQNYKLYYMEKGTDK-EQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHG 616
Score = 47.2 bits (107), Expect = 3e-04
Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 12/175 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD--YEIFSSRRTAITTDESTSV 241
P F+ D ++ V + + PSP I W KD + S R + D S +
Sbjct: 52 PFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 242 --LLFHQILPSDEGEIKCTATNRG-GHAVTK-ARLCLEAAPKLRYPRQYEDGLLYEINET 297
++ + DEG +C AT G +++ A+L + P R+ Q E +Y N
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP--RFTSQPEPSSVYAGNNA 169
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L + P + W + P++ DDR+ I +L I +A D G Y+
Sbjct: 170 I-LNCEVNADLVPFVRWEQNRQPLLLDDRV---IKLPSGMLVISNATEGDGGLYR 220
Score = 46.8 bits (106), Expect = 4e-04
Identities = 31/102 (30%), Positives = 53/102 (51%), Gaps = 10/102 (9%)
Query: 373 PPDPPRNVSVTRQVDKSVTL--DWEPPADDGGCKVGNYIVEYYRTGWNV----W-LKAIT 425
P PP++V+V + K T+ +W+PP++ G K+ YI+ YY T N W ++ +
Sbjct: 954 PTSPPKDVTVVSKEGKPKTIIVNWQPPSEANG-KITGYII-YYSTDVNAEIHDWVIEPVV 1011
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
+ + +L + Y F+I+A + GM P SE+ R P
Sbjct: 1012 GNRLTHQIQELTLDTPYYFKIQARNSKGM-GPMSEAVQFRTP 1052
Score = 35.9 bits (79), Expect = 0.78
Identities = 46/234 (19%), Positives = 92/234 (39%), Gaps = 11/234 (4%)
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
E + R T+ + ++P+ + A N+ G + A L +E P+++ P
Sbjct: 480 EGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLP 539
Query: 284 RQYEDGLLYEINETIFLKT--TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIH 341
+ Y + T T T V ++ TD ++ ++ I+
Sbjct: 540 GPAPNLRAYAASPTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQDVDVSSHSYT--IN 597
Query: 342 SAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPP 397
K+ +++ A N G + V V P P+N+S+ + KS+ + W+PP
Sbjct: 598 GLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPP 657
Query: 398 AD-DGGCKVGNYIVEYYRTG--WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKA 448
A ++ Y + Y + +V ++ + + + L G+EY FR+ A
Sbjct: 658 APATQNGQITGYKIRYRKASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAA 711
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 91.1 bits (216), Expect = 2e-17
Identities = 92/324 (28%), Positives = 132/324 (40%), Gaps = 31/324 (9%)
Query: 167 SELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE-- 224
+E S LTV + EPP F+ + D V F +G P P I W ++ +
Sbjct: 300 AEASATLTV---QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 225 IFSSRRTAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
+FS + ++ S S L + SD G C N G +TKA L + R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 282 YPRQYEDGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPIIT-DDRIEISITPKFSV 337
P G + + ++ T L G P PTI WR DG + T D RI+ + V
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIK---QLENGV 473
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDT-AAFL------VTVTAP--------PDPPRNVSV 382
L+I AK D G Y A GE T +A++ V V P P P V
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEV 533
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT-LFDLIEGSE 441
T +VTL W+P + G I + + W + KT + + L +
Sbjct: 534 TDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAI 593
Query: 442 YKFRIKAESPYGMSAPSSESSPVR 465
Y F ++A + YG+S PS S PV+
Sbjct: 594 YLFLVRAANAYGISDPSQISDPVK 617
Score = 76.2 bits (179), Expect = 6e-13
Identities = 61/217 (28%), Positives = 90/217 (41%), Gaps = 10/217 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F+KR ++ +D EF G P PT+ W KDD E+ SR D+ T L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE--IRDDHT--L 276
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
++ D G C A N G A A L ++ + + + + T+ +
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKN 357
G P P I WR +G + + +FSV L I + +RSD G Y Q N
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396
Query: 358 IIGE-DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ G T A+L D P V V+++V +D
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 433
Score = 66.9 bits (156), Expect = 4e-10
Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 20/238 (8%)
Query: 176 SSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYEIFS 227
S R QE PP ++ D+ + + + G P+PTI W+K D +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 77
Query: 228 SRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
S R + + + + H + DEG C A N G AV+ LE A RQ
Sbjct: 78 SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH-NASLEVAILRDDFRQN 136
Query: 287 EDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
++ + E ++ G P PTI W+ DG P+ DD+ E IT + L I ++
Sbjct: 137 PSDVMVVVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDE-RITIRGGKLMITYTRK 193
Query: 346 SDRGEYQIQAKNIIGE-DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVTLDWEPPAD 399
SD G+Y N++GE ++ +TV P P N++VT VD S E D
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVT--VDDSAEFKCEARGD 249
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P+ P KP++ +D N +TL W P + G P Y +E + + W +T V
Sbjct: 525 PSAPSKPEV----TDVSRNTVTLSWQPNLNSGATPT-SYIIEAFSHASGSSW-QTVAENV 578
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL+P Y F V A N G S+ S++SD
Sbjct: 579 KTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Score = 41.1 bits (92), Expect = 0.021
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 16/142 (11%)
Query: 272 LCLEAAPKLRY----PR--QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT-- 323
+CL + +LR PR ++ L+ E L G+PTPTIEW G + T
Sbjct: 14 ICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDK 73
Query: 324 -DDRIEISITPK---FSVLKIHSAK-RSDRGEYQIQAKNIIGEDTA--AFLVTVTAPPDP 376
D R + P F + +H K R D G Y A+N +GE + A L D
Sbjct: 74 DDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF 133
Query: 377 PRNVS-VTRQVDKSVTLDWEPP 397
+N S V V + ++ +PP
Sbjct: 134 RQNPSDVMVVVGEPAVMECQPP 155
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 91.1 bits (216), Expect = 2e-17
Identities = 92/324 (28%), Positives = 132/324 (40%), Gaps = 31/324 (9%)
Query: 167 SELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE-- 224
+E S LTV + EPP F+ + D V F +G P P I W ++ +
Sbjct: 300 AEASATLTV---QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 225 IFSSRRTAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
+FS + ++ S S L + SD G C N G +TKA L + R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 282 YPRQYEDGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPIIT-DDRIEISITPKFSV 337
P G + + ++ T L G P PTI WR DG + T D RI+ + V
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIK---QLENGV 473
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDT-AAFL------VTVTAP--------PDPPRNVSV 382
L+I AK D G Y A GE T +A++ V V P P P V
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEV 533
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT-LFDLIEGSE 441
T +VTL W+P + G I + + W + KT + + L +
Sbjct: 534 TDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAI 593
Query: 442 YKFRIKAESPYGMSAPSSESSPVR 465
Y F ++A + YG+S PS S PV+
Sbjct: 594 YLFLVRAANAYGISDPSQISDPVK 617
Score = 76.2 bits (179), Expect = 6e-13
Identities = 61/217 (28%), Positives = 90/217 (41%), Gaps = 10/217 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F+KR ++ +D EF G P PT+ W KDD E+ SR D+ T L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE--IRDDHT--L 276
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
++ D G C A N G A A L ++ + + + + T+ +
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKN 357
G P P I WR +G + + +FSV L I + +RSD G Y Q N
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396
Query: 358 IIGE-DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ G T A+L D P V V+++V +D
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 433
Score = 67.3 bits (157), Expect = 3e-10
Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 20/238 (8%)
Query: 176 SSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYEIFS 227
S R QE PP ++ D+ + + + G P+PTI W+K D +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 77
Query: 228 SRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
S R + + + + H + DEG C A N G AV+ LE A RQ
Sbjct: 78 SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH-NASLEVAILRDDFRQN 136
Query: 287 EDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
++ + E ++ G P PTI W+ DG P+ DD+ E IT + L I ++
Sbjct: 137 PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDE-RITIRGGKLMITYTRK 193
Query: 346 SDRGEYQIQAKNIIGE-DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVTLDWEPPAD 399
SD G+Y N++GE ++ +TV P P N++VT VD S E D
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVT--VDDSAEFKCEARGD 249
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P+ P KP++ +D N +TL W P + G P Y +E + + W +T V
Sbjct: 525 PSAPSKPEV----TDVSRNTVTLSWQPNLNSGATPT-SYIIEAFSHASGSSW-QTVAENV 578
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL+P Y F V A N G S+ S++SD
Sbjct: 579 KTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Score = 41.5 bits (93), Expect = 0.016
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 16/142 (11%)
Query: 272 LCLEAAPKLRY----PR--QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT-- 323
+CL + +LR PR ++ L+ E L G+PTPTIEW G + T
Sbjct: 14 ICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDK 73
Query: 324 -DDRIEISITPK---FSVLKIHSAK-RSDRGEYQIQAKNIIGEDTA--AFLVTVTAPPDP 376
D R + P F + +H K R D G Y A+N +GE + A L D
Sbjct: 74 DDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF 133
Query: 377 PRNVS-VTRQVDKSVTLDWEPP 397
+N S V V + ++ +PP
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPP 155
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 91.1 bits (216), Expect = 2e-17
Identities = 92/324 (28%), Positives = 132/324 (40%), Gaps = 31/324 (9%)
Query: 167 SELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE-- 224
+E S LTV + EPP F+ + D V F +G P P I W ++ +
Sbjct: 300 AEASATLTV---QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNL 356
Query: 225 IFSSRRTAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
+FS + ++ S S L + SD G C N G +TKA L + R
Sbjct: 357 LFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADR 416
Query: 282 YPRQYEDGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPIIT-DDRIEISITPKFSV 337
P G + + ++ T L G P PTI WR DG + T D RI+ + V
Sbjct: 417 PPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIK---QLENGV 473
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDT-AAFL------VTVTAP--------PDPPRNVSV 382
L+I AK D G Y A GE T +A++ V V P P P V
Sbjct: 474 LQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEV 533
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVT-LFDLIEGSE 441
T +VTL W+P + G I + + W + KT + + L +
Sbjct: 534 TDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAI 593
Query: 442 YKFRIKAESPYGMSAPSSESSPVR 465
Y F ++A + YG+S PS S PV+
Sbjct: 594 YLFLVRAANAYGISDPSQISDPVK 617
Score = 76.2 bits (179), Expect = 6e-13
Identities = 61/217 (28%), Positives = 90/217 (41%), Gaps = 10/217 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F+KR ++ +D EF G P PT+ W KDD E+ SR D+ T L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE--IRDDHT--L 276
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
++ D G C A N G A A L ++ + + + + T+ +
Sbjct: 277 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQC 336
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKN 357
G P P I WR +G + + +FSV L I + +RSD G Y Q N
Sbjct: 337 EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLN 396
Query: 358 IIGE-DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
+ G T A+L D P V V+++V +D
Sbjct: 397 VAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 433
Score = 67.3 bits (157), Expect = 3e-10
Identities = 68/238 (28%), Positives = 102/238 (42%), Gaps = 20/238 (8%)
Query: 176 SSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYEIFS 227
S R QE PP ++ D+ + + + G P+PTI W+K D +
Sbjct: 18 SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 77
Query: 228 SRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
S R + + + + H + DEG C A N G AV+ LE A RQ
Sbjct: 78 SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH-NASLEVAILRDDFRQN 136
Query: 287 EDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
++ + E ++ G P PTI W+ DG P+ DD+ E IT + L I ++
Sbjct: 137 PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDE-RITIRGGKLMITYTRK 193
Query: 346 SDRGEYQIQAKNIIGE-DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVTLDWEPPAD 399
SD G+Y N++GE ++ +TV P P N++VT VD S E D
Sbjct: 194 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVT--VDDSAEFKCEARGD 249
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P+ P KP++ +D N +TL W P + G P Y +E + + W +T V
Sbjct: 525 PSAPSKPEV----TDVSRNTVTLSWQPNLNSGATPT-SYIIEAFSHASGSSW-QTVAENV 578
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL+P Y F V A N G S+ S++SD
Sbjct: 579 KTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 614
Score = 41.5 bits (93), Expect = 0.016
Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 16/142 (11%)
Query: 272 LCLEAAPKLRY----PR--QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT-- 323
+CL + +LR PR ++ L+ E L G+PTPTIEW G + T
Sbjct: 14 ICLCSGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDK 73
Query: 324 -DDRIEISITPK---FSVLKIHSAK-RSDRGEYQIQAKNIIGEDTA--AFLVTVTAPPDP 376
D R + P F + +H K R D G Y A+N +GE + A L D
Sbjct: 74 DDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDF 133
Query: 377 PRNVS-VTRQVDKSVTLDWEPP 397
+N S V V + ++ +PP
Sbjct: 134 RQNPSDVMVAVGEPAVMECQPP 155
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 91.1 bits (216), Expect = 2e-17
Identities = 93/346 (26%), Positives = 143/346 (41%), Gaps = 34/346 (9%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS----QEPPVFIKRLEDVTALENDKVEF 204
H + R D+G +Y+ +++ + ++ ++ QEPP F+ + D V F
Sbjct: 313 HTLKIRKVTAGDMG--SYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVALGRTVTF 370
Query: 205 HVTFSGIPSPTIAWFKDDYE--IFSSRRTAITTDESTSV---LLFHQILPSDEGEIKCTA 259
+G P P I W ++ + +FS + ++ S S L + SD G C
Sbjct: 371 QCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 430
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE---INETIFLKTTIVGKPTPTIEWRH 316
N G +TKA L + R P G + + ++ T L G P PTI WR
Sbjct: 431 LNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 490
Query: 317 DGHPIIT-DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT-AAFL------V 368
DG + T D RI+ + VL+I AK D G Y A GE T +A++ V
Sbjct: 491 DGVLVSTQDSRIK---QLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGV 547
Query: 369 TVTAP--------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
V P P P VT +VTL W+P + G I + + W
Sbjct: 548 PVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSW 607
Query: 421 LKAITSRKTNVT-LFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ KT + + L + Y F ++A + YG+S PS S PV+
Sbjct: 608 QTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVK 653
Score = 77.4 bits (182), Expect = 3e-13
Identities = 64/218 (29%), Positives = 92/218 (42%), Gaps = 15/218 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F+KR ++ +D EF G P PT+ W KDD E+ SR D+ T L
Sbjct: 260 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYE--IRDDHT--L 315
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEINETIFLK 301
++ D G C A N G A A L ++ P + PR + + T+ +
Sbjct: 316 KIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQ----VVALGRTVTFQ 371
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAK 356
G P P I WR +G + + +FSV L I + +RSD G Y Q
Sbjct: 372 CEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTL 431
Query: 357 NIIGE-DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
N+ G T A+L D P V V+++V +D
Sbjct: 432 NVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 469
Score = 66.5 bits (155), Expect = 5e-10
Identities = 67/238 (28%), Positives = 101/238 (42%), Gaps = 18/238 (7%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK------DDYEIFS 227
T S R PP ++ D+ + + + G P+PTI W+K D +
Sbjct: 57 TGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPR 116
Query: 228 SRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
S R + + + + H + DEG C A N G AV+ LE A RQ
Sbjct: 117 SHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSH-NASLEVAILRDDFRQN 175
Query: 287 EDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
++ + E ++ G P PTI W+ DG P+ DD+ E IT + L I ++
Sbjct: 176 PSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPL--DDKDE-RITIRGGKLMITYTRK 232
Query: 346 SDRGEYQIQAKNIIGE-DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVTLDWEPPAD 399
SD G+Y N++GE ++ +TV P P N++VT VD S E D
Sbjct: 233 SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVT--VDDSAEFKCEARGD 288
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P+ P KP++ +D N +TL W P + G P Y +E + + W +T V
Sbjct: 561 PSAPSKPEV----TDVSRNTVTLSWQPNLNSGATPT-SYIIEAFSHASGSSW-QTVAENV 614
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL+P Y F V A N G S+ S++SD
Sbjct: 615 KTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 650
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 89.4 bits (212), Expect = 6e-17
Identities = 57/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ I++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1211 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1270
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1271 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1331 YKFRVRAINVYGTSEPSQES 1350
Score = 72.9 bits (171), Expect = 6e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 613
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
Score = 56.0 bits (129), Expect = 7e-07
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1688 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1747
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A +E
Sbjct: 1748 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1779
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1319
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV 175
+ L P H+Y+FRV A+N G S S+ S++ TV
Sbjct: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTV 1355
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 501
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDT 621
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/94 (25%), Positives = 42/94 (44%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ L D G KC A N G A ++ ++ AP
Sbjct: 1089 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1046 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKN 1105
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1106 DAGQAECSCQVTVDDAP 1122
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 89.4 bits (212), Expect = 6e-17
Identities = 57/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ I++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1280 DSEHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1340 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1400 YKFRVRAINVYGTSEPSQES 1419
Score = 72.9 bits (171), Expect = 6e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 742
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 743 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLL 243
P F + + EN V+F SGIP P +AWF + + + + D + L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 244 FHQILPSDEGEIKCTATNRGGH-----AVTKARLC-LEAAPKLRYPRQYEDGLLYEINET 297
+ D G CTA+N G + RL +E AP + +D + E +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPS--FSSVLKDCAVIE-GQD 530
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
L+ ++ G P P I W +G PI + + L I A D G Y A+N
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 358 IIGEDTAAFLVTV 370
+G+ + + VTV
Sbjct: 588 ALGQVSCSAWVTV 600
Score = 56.0 bits (129), Expect = 7e-07
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1757 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1816
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A +E
Sbjct: 1817 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 1848
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1388
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV 175
+ L P H+Y+FRV A+N G S S+ S++ TV
Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTV 1424
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 570
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDT 690
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 43.2 bits (97), Expect = 0.005
Identities = 24/94 (25%), Positives = 42/94 (44%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ L D G KC A N G A ++ ++ AP
Sbjct: 1158 EKALLEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKCVAKN 1174
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1175 DAGQAECSCQVTVDDAP 1191
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 89.0 bits (211), Expect = 8e-17
Identities = 85/338 (25%), Positives = 139/338 (41%), Gaps = 26/338 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++ L+P +R +A N +E + + SD F++R +V A+E
Sbjct: 197 LQISRLQPGDIGIYRCSARNPASSRTGNEAE--VRILSDPGLHRQLYFLQRPSNVVAIEG 254
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
SG P P+ W + + E+ R + ++ LL + D G C
Sbjct: 255 KDAVLECCVSGYPPPSFTWLRGE-EVIQLRSKKYSLLGGSN-LLISNVTDDDSGMYTCVV 312
Query: 260 TNRGGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
T + + A L + P L +P YE + F + T+ GKP PT+ W +G
Sbjct: 313 TYKNENISASAELTVLVPPWFLNHPSNL---YAYESMDIEF-ECTVSGKPVPTVNWMKNG 368
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP----- 373
+I D +I S L+I +SD G YQ A+N G + + V P
Sbjct: 369 DVVIPSDYFQI---VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSS 425
Query: 374 ---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR--K 428
P PR+V + V L W PPA+ G + + V + R G N T++
Sbjct: 426 SVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKG-NIQTFTVFFSREGDNRERALNTTQPGS 484
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+T+ +L + Y FR+ A + +G P S P+++
Sbjct: 485 LQLTVGNLKPEAMYTFRVVAYNEWG---PGESSQPIKV 519
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/215 (21%), Positives = 84/215 (39%), Gaps = 6/215 (2%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
++ + +++ ++ A P F+ + E VTA D V G P PTI W K+
Sbjct: 119 ASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQ 178
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN-RGGHAVTKARLCLEAAPKLR- 281
++ + + L ++ P D G +C+A N +A + + + P L
Sbjct: 179 DLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHR 238
Query: 282 --YPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
Y Q ++ + L+ + G P P+ W G +I + S+ ++L
Sbjct: 239 QLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLL- 296
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I + D G Y +A+ +TV PP
Sbjct: 297 ISNVTDDDSGMYTCVVTYKNENISASAELTVLVPP 331
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/102 (21%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 359 IGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW-EPPADDGGCKVGNYIVEYYRTGW 417
+ D + P PP+NVS+ +S+ + W PP+ + Y + + +T
Sbjct: 608 VSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR 667
Query: 418 NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
++ + L +GS+Y F++ A + G PS+
Sbjct: 668 RGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 89.0 bits (211), Expect = 8e-17
Identities = 85/338 (25%), Positives = 139/338 (41%), Gaps = 26/338 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++ L+P +R +A N +E + + SD F++R +V A+E
Sbjct: 197 LQISRLQPGDIGIYRCSARNPASSRTGNEAE--VRILSDPGLHRQLYFLQRPSNVVAIEG 254
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
SG P P+ W + + E+ R + ++ LL + D G C
Sbjct: 255 KDAVLECCVSGYPPPSFTWLRGE-EVIQLRSKKYSLLGGSN-LLISNVTDDDSGMYTCVV 312
Query: 260 TNRGGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
T + + A L + P L +P YE + F + T+ GKP PT+ W +G
Sbjct: 313 TYKNENISASAELTVLVPPWFLNHPSNL---YAYESMDIEF-ECTVSGKPVPTVNWMKNG 368
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP----- 373
+I D +I S L+I +SD G YQ A+N G + + V P
Sbjct: 369 DVVIPSDYFQI---VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSS 425
Query: 374 ---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR--K 428
P PR+V + V L W PPA+ G + + V + R G N T++
Sbjct: 426 SVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKG-NIQTFTVFFSREGDNRERALNTTQPGS 484
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+T+ +L + Y FR+ A + +G P S P+++
Sbjct: 485 LQLTVGNLKPEAMYTFRVVAYNEWG---PGESSQPIKV 519
Score = 42.3 bits (95), Expect = 0.009
Identities = 46/215 (21%), Positives = 84/215 (39%), Gaps = 6/215 (2%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
++ + +++ ++ A P F+ + E VTA D V G P PTI W K+
Sbjct: 119 ASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQ 178
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN-RGGHAVTKARLCLEAAPKLR- 281
++ + + L ++ P D G +C+A N +A + + + P L
Sbjct: 179 DLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHR 238
Query: 282 --YPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
Y Q ++ + L+ + G P P+ W G +I + S+ ++L
Sbjct: 239 QLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLL- 296
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I + D G Y +A+ +TV PP
Sbjct: 297 ISNVTDDDSGMYTCVVTYKNENISASAELTVLVPP 331
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/102 (21%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 359 IGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW-EPPADDGGCKVGNYIVEYYRTGW 417
+ D + P PP+NVS+ +S+ + W PP+ + Y + + +T
Sbjct: 608 VSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR 667
Query: 418 NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
++ + L +GS+Y F++ A + G PS+
Sbjct: 668 RGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 709
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1340 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1400 YKFRVRAINVYGTSEPSQES 1419
Score = 72.9 bits (171), Expect = 6e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 682
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 742
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 743 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLL 243
P F + + EN V+F SGIP P +AWF + + + + D + L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 244 FHQILPSDEGEIKCTATNRGGH-----AVTKARLC-LEAAPKLRYPRQYEDGLLYEINET 297
+ D G CTA+N G + RL +E AP + +D + E +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPS--FSSVLKDCAVIE-GQD 530
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
L+ ++ G P P I W +G PI + + L I A D G Y A+N
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 358 IIGEDTAAFLVTV 370
+G+ + + VTV
Sbjct: 588 ALGQVSCSAWVTV 600
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1388
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 1440
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDI 1466
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 570
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDT 690
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1175 DAGQAECSCQVTVDDAP 1191
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 88.2 bits (209), Expect = 1e-16
Identities = 85/338 (25%), Positives = 139/338 (41%), Gaps = 26/338 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++ L+P +R +A N +E + + SD F++R +V A+E
Sbjct: 131 LQISRLQPGDIGIYRCSARNPASSRTGNEAE--VRILSDPGLHRQLYFLQRPSNVVAIEG 188
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
SG P P+ W + + E+ R + ++ LL + D G C
Sbjct: 189 KDAVLEGCVSGYPPPSFTWLRGE-EVIQLRSKKYSLLGGSN-LLISNVTDDDSGMYTCVV 246
Query: 260 TNRGGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG 318
T + + A L + P L +P YE + F + T+ GKP PT+ W +G
Sbjct: 247 TYKNENISASAELTVLVPPWFLNHPSNL---YAYESMDIEF-ECTVSGKPVPTVNWMKNG 302
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP----- 373
+I D +I S L+I +SD G YQ A+N G + + V P
Sbjct: 303 DVVIPSDYFQI---VGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSS 359
Query: 374 ---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSR--K 428
P PR+V + V L W PPA+ G + + V + R G N T++
Sbjct: 360 SVLPSAPRDVVPVLVSSRFVRLSWRPPAEAKG-NIQTFTVFFSREGDNRERALNTTQPGS 418
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+T+ +L + Y FR+ A + +G P S P+++
Sbjct: 419 LQLTVGNLKPEAMYTFRVVAYNEWG---PGESSQPIKV 453
Score = 41.9 bits (94), Expect = 0.012
Identities = 46/215 (21%), Positives = 84/215 (39%), Gaps = 6/215 (2%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
++ + +++ ++ A P F+ + E VTA D V G P PTI W K+
Sbjct: 53 ASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQ 112
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN-RGGHAVTKARLCLEAAPKLR- 281
++ + + L ++ P D G +C+A N +A + + + P L
Sbjct: 113 DLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHR 172
Query: 282 --YPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
Y Q ++ + L+ + G P P+ W G +I + S+ ++L
Sbjct: 173 QLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLL- 230
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I + D G Y +A+ +TV PP
Sbjct: 231 ISNVTDDDSGMYTCVVTYKNENISASAELTVLVPP 265
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/102 (21%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 359 IGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDW-EPPADDGGCKVGNYIVEYYRTGW 417
+ D + P PP+NVS+ +S+ + W PP+ + Y + + +T
Sbjct: 542 VSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTR 601
Query: 418 NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
++ + L +GS+Y F++ A + G PS+
Sbjct: 602 RGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSN 643
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1340 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1400 YKFRVRAINVYGTSEPSQES 1419
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 742
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 743 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 59.3 bits (137), Expect = 7e-08
Identities = 50/193 (25%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLL 243
P F + + EN V+F SGIP P +AWF + + + + + + L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473
Query: 244 FHQILPSDEGEIKCTATNRGGH-----AVTKARLC-LEAAPKLRYPRQYEDGLLYEINET 297
+ D G CTA+N G + RL +E AP + +D + E +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPS--FSSVLKDCAVIE-GQD 530
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
L+ ++ G P P I W +G PI + + L I A D G Y A+N
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 358 IIGEDTAAFLVTV 370
+G+ + + VTV
Sbjct: 588 ALGQVSCSAWVTV 600
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1388
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 1440
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDI 1466
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 570
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1175 DAGQAECSCQVTVDDAP 1191
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1270
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1271 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1331 YKFRVRAINVYGTSEPSQES 1350
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1319
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 1371
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDI 1397
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 501
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1046 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1106 DAGQAECSCQVTVDDAP 1122
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1340 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1400 YKFRVRAINVYGTSEPSQES 1419
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 623 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 683 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 742
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 743 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-AITTDESTSVLL 243
P F + + EN V+F SGIP P +AWF + + + + D + L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
Query: 244 FHQILPSDEGEIKCTATNRGGH-----AVTKARLC-LEAAPKLRYPRQYEDGLLYEINET 297
+ D G CTA+N G + RL +E AP + +D + E +
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPS--FSSVLKDCAVIE-GQD 530
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
L+ ++ G P P I W +G PI + + L I A D G Y A+N
Sbjct: 531 FVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
Query: 358 IIGEDTAAFLVTV 370
+G+ + + VTV
Sbjct: 588 ALGQVSCSAWVTV 600
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1388
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 1389 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 1440
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDI 1466
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 514 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 570
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 691 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1175 DAGQAECSCQVTVDDAP 1191
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1270
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 1271 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 1331 YKFRVRAINVYGTSEPSQES 1350
Score = 72.9 bits (171), Expect = 6e-12
Identities = 44/180 (24%), Positives = 73/180 (40%), Gaps = 3/180 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F++ L D+ ++ +V V SG P P + W + EI S + L
Sbjct: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWI 613
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP--RQYEDGLLYEINETIFLKT 302
++ P D G C A N G T+A L ++ P + + +++ +
Sbjct: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
Query: 303 TIVGKPTPTIEWRHDGHPIITD-DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P PT+ W DG + D E+ L + + G+Y+I KN +GE
Sbjct: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 1740 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1799
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 1800 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1831
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 1319
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 1371
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDI 1397
Score = 49.6 bits (113), Expect = 6e-05
Identities = 56/224 (25%), Positives = 80/224 (35%), Gaps = 21/224 (9%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F L+D +E + G P P I W + I +R T + + L
Sbjct: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHI 501
Query: 245 HQILPSDEGEIKCTATNRGGHA-----VT--------KARLCLEAAPKLRYPRQYEDGL- 290
LP D G C A N G VT K+ L AP + GL
Sbjct: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
Query: 291 -LYEINET-IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
L ++ + + + + G P P + W H+G+ I + L I D
Sbjct: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDT 621
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPPD--PPRNVSVTRQVDKSV 390
G Y +A N GE ++TV P D P +S R V S+
Sbjct: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
Score = 48.8 bits (111), Expect = 1e-04
Identities = 25/92 (27%), Positives = 36/92 (39%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP F +L V E F +G P P + W K + + S R +++ VL
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
H + D G C N G A A L ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
Score = 41.9 bits (94), Expect = 0.012
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD-ESTSV 241
E P FI ++ E +F G P P + W ++ I S R + T
Sbjct: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
L+ H + D G+ C ATN G L +E +
Sbjct: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
Score = 39.9 bits (89), Expect = 0.048
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%)
Query: 306 GKPTPTIEWRHDGHPIITDDR--IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W +G PI + R ++ I FS L IH+ DRG+Y +A N G
Sbjct: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQ 116
Query: 364 AAFLVTV 370
+TV
Sbjct: 117 VTVELTV 123
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 1046 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 1106 DAGQAECSCQVTVDDAP 1122
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/58 (29%), Positives = 25/58 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G+P P + W P+ R+ +S VL+IH + D G Y N G+
Sbjct: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 298 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 357
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 358 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 417
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 418 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 477
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 478 YKFRVRAINVYGTSEPSQES 497
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 887 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 946
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 947 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 978
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 409 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 466
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 467 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 518
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 519 DEKEPEVDYRTVTINTEQKVSDFYDI 544
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 269
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 193 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 252
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 253 DAGQAECSCQVTVDDAP 269
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2587
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2588 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2645
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2646 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2705
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2706 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Query: 372 APP 374
PP
Sbjct: 2764 VPP 2766
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 1358 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGK 1414
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 1473
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 1533 KQAKDIKLTIYIPP 1546
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3314
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3315 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 3374
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3375 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3432
Query: 373 PPD 375
PP+
Sbjct: 3433 PPN 3435
Score = 79.8 bits (188), Expect = 5e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3176 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3235
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3236 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3294
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3295 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3500
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3501 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3559
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3560 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3617
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3618 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3647
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 6/182 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + V + P
Sbjct: 2137 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 374 PD 375
P+
Sbjct: 2195 PN 2196
Score = 77.8 bits (183), Expect = 2e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 3024 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3080
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3081 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3138
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3139 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3171
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
D G C ATN G + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLCE 2219
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAK 2279
Query: 364 AAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2315
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2203 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2262
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2322
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2323 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2409
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4136 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4187
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4188 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4245
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4246 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Score = 73.3 bits (172), Expect = 4e-12
Identities = 45/182 (24%), Positives = 74/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2358
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+I
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSI 2418
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2419 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2476
Query: 373 PP 374
PP
Sbjct: 2477 PP 2478
Score = 71.7 bits (168), Expect = 1e-11
Identities = 59/253 (23%), Positives = 102/253 (40%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2326 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+I WFKD + + S I + +
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRM 2441
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2500
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2501 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2558
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2559 KSRSFSLNVFVSP 2571
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 1520
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 1579
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1580 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 1637
Query: 373 PP 374
PP
Sbjct: 1638 PP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2739
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2797
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2798 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2855
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2856 EDSLQYDVRVLVPP 2869
Score = 70.9 bits (166), Expect = 2e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2937
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2995
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2996 LSWLKNEQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVY 3053
Query: 372 APP 374
PP
Sbjct: 3054 VPP 3056
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3123
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3124 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3181
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3182 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Query: 371 TAPP 374
PP
Sbjct: 3242 QVPP 3245
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4043
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4100
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4101 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4157
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4158 STSTKLTVHVPP 4169
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3745 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3802
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACE 3826
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3890 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3949
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3950 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4004
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4062
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4063 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4122
Query: 413 YR 414
R
Sbjct: 4123 IR 4124
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4346 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4404
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4405 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4458
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4459 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4515
Query: 360 G 360
G
Sbjct: 4516 G 4516
Score = 62.1 bits (144), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3712 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3771
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3772 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3827
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3828 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3885
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3886 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3917
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 3350 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 3407
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 3408 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 3466
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 3467 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 3524
Query: 372 APP 374
PP
Sbjct: 3525 EPP 3527
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 1105
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 1106 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 1163
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 1164 KLNVHVPP 1171
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 54.4 bits (125), Expect = 2e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4315
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4373
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4374 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4430
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4431 SMSLTLQSPP 4440
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4179 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4236
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4237 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4293
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4294 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 4349
Score = 39.1 bits (87), Expect = 0.084
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 85.8 bits (203), Expect = 7e-16
Identities = 66/243 (27%), Positives = 101/243 (41%), Gaps = 19/243 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVL---TVSSDRASQEPPVFIKRLEDVTA 196
L +T ++ PH ++ A + GH + S +V T++ + P EDVT
Sbjct: 2536 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNP-------EDVTV 2588
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
+ N P TI WFKD + S+R I T +L Q + G
Sbjct: 2589 ILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQ--EDNAGRYS 2646
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL-----YEINETIFLKTTIVGKPTPT 311
C ATN G + + + P + + GL ++N T+ L+ P+ +
Sbjct: 2647 CVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSAS 2706
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ +DD + I+ L+I A+ SD G Y A NI GED F V +
Sbjct: 2707 LSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2764
Query: 372 APP 374
PP
Sbjct: 2765 VPP 2767
Score = 84.6 bits (200), Expect = 2e-15
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 6/193 (3%)
Query: 184 PPVFI--KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
PPV +++ +V+ L N G PSP I W+KD+ ++ S + I T + +
Sbjct: 1358 PPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGKI 1415
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + P D G C A N G + + + P + + + +N + L+
Sbjct: 1416 LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPKEVSVVLNRDVALE 1474
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G+
Sbjct: 1475 CQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGK 1533
Query: 362 DTAAFLVTVTAPP 374
+T+ PP
Sbjct: 1534 QAKDIKLTIYIPP 1546
Score = 84.2 bits (199), Expect = 2e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 3256 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 3315
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 3316 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTPPPQI 3375
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 3376 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 3433
Query: 373 PPD 375
PP+
Sbjct: 3434 PPN 3436
Score = 80.2 bits (189), Expect = 4e-14
Identities = 58/199 (29%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 1259 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 1316
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 1317 LEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVSN-VSVLLN 1375
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ K +LK+ A D G Y +A
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKA 1433
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 1434 INIAGTSQKYFNIDVLVPP 1452
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 3444 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 3501
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 3502 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 3560
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 3561 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 3618
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 3619 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 3648
Score = 79.0 bits (186), Expect = 8e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 3177 TGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 3236
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 3237 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 3295
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 3296 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3341
Score = 75.8 bits (178), Expect = 8e-13
Identities = 51/183 (27%), Positives = 78/183 (42%), Gaps = 7/183 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 2021 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSTQISDTG 2079
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 2080 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 2136
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-DTAAFLVTVTA 372
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G+ + + V +
Sbjct: 2137 WLKDGHPLL--KKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWV 2194
Query: 373 PPD 375
PP+
Sbjct: 2195 PPN 2197
Score = 75.8 bits (178), Expect = 8e-13
Identities = 56/213 (26%), Positives = 91/213 (42%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K+ I + T I T ++
Sbjct: 2965 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQII 3024
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N G + K L + P ++ E + + E ++ L+
Sbjct: 3025 RAKV--SDGGEYTCIAINXAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 3081
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 3082 CESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 3139
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 3140 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 3172
Score = 75.4 bits (177), Expect = 1e-12
Identities = 52/209 (24%), Positives = 87/209 (41%), Gaps = 8/209 (3%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L +T +E + + SGIP P + W K + + + L S
Sbjct: 2204 LTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKS 2263
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D C A+N G A + L + P + + ++ ++I L+ + G P P
Sbjct: 2264 DAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPP 2323
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ W DGHP+I +E I + +L++ + SD G Y A N+ G + ++V
Sbjct: 2324 TVTWMKDGHPLIKAKGVE--ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2381
Query: 371 TAPPD------PPRNVSVTRQVDKSVTLD 393
APP P N+SV + S+T +
Sbjct: 2382 HAPPSIIGNHRSPENISVVEKNSVSLTCE 2410
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 694 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 750
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFI---QEPADVSMEIG 807
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 808 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 867
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 868 EAENQFGKIQSETTVTVTGLVAPLIGIS 895
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 4077 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4136
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 4137 AF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 4188
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 4189 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 4246
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 4247 GEDTHTVSLTVHVLPTFTELPGDVSLNK 4274
Score = 72.9 bits (171), Expect = 6e-12
Identities = 50/182 (27%), Positives = 76/182 (41%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 1556 DISVLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 1613
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPIL 1673
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 1674 TWLKDGVPVKANDNFRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731
Query: 373 PP 374
PP
Sbjct: 1732 PP 1733
Score = 72.9 bits (171), Expect = 6e-12
Identities = 58/219 (26%), Positives = 92/219 (42%), Gaps = 12/219 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 2103 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 2160
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTK-ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G C ATN G K + + P + + + E N I L
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVIEGN-LISLLC 2219
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P + W+ G P++TD + I L+I A++SD Y A N+ G
Sbjct: 2220 ESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTA 2279
Query: 363 TAAFLV------TVTAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + T+T P + VTR KS++L+ E
Sbjct: 2280 KKEYNLQVYIRPTITNSGSHPTEIIVTR--GKSISLECE 2316
Score = 72.1 bits (169), Expect = 1e-11
Identities = 55/183 (30%), Positives = 74/183 (40%), Gaps = 6/183 (3%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E+VT L N SG P+P +W KD + ++ +L QI +D
Sbjct: 2881 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TD 2938
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G C A N G A L + P + P+ + L +N I L + G P P
Sbjct: 2939 IGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKS--ENLTVVVNNFISLTCEVSGFPPPD 2996
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W + PI + I P L+I AK SD GEY A N GE F +TV
Sbjct: 2997 LSWLKNXQPIKLNTNT--LIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVY 3054
Query: 372 APP 374
PP
Sbjct: 3055 VPP 3057
Score = 71.7 bits (168), Expect = 1e-11
Identities = 51/183 (27%), Positives = 72/183 (39%), Gaps = 4/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V+ + N V G P P I WFKD +F D VL +D
Sbjct: 1461 KEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRND 1519
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+G +CT +N G +L + P ++ D + IN I L+ G P P
Sbjct: 1520 KGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECKTRGLPMPA 1578
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
I W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 1579 ITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVY 1636
Query: 372 APP 374
PP
Sbjct: 1637 VPP 1639
Score = 71.3 bits (167), Expect = 2e-11
Identities = 44/182 (24%), Positives = 73/182 (40%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
++ + GIP PT+ W KD + + ++ I DE +L I SD
Sbjct: 2302 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEIL-DEG-HILQLKNIHVSDT 2359
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C A N G K L + A P + + + + ++ L G P P+
Sbjct: 2360 GRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPST 2419
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ + + I + +L++ D G+Y +N GE+ F ++V
Sbjct: 2420 TWFKDGWPVSLSNSVRILSGGR--MLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLV 2477
Query: 373 PP 374
PP
Sbjct: 2478 PP 2479
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/194 (28%), Positives = 83/194 (42%), Gaps = 17/194 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
++V N+ + IPS +++W+KD + S I + T + QI SD
Sbjct: 2683 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI--SD 2740
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE-----------INETIFL 300
G C A+N G + ++ P + + +E G + + IN I L
Sbjct: 2741 TGRYTCVASNIAGEDELDFDVNIQVPPS--FQKLWEIGNMLDTGRNGEAKDVIINNPISL 2798
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P PT+ W DGHP+ + D++ I P VL+I AK D G Y A N G
Sbjct: 2799 YCETNAAPPPTLTWYKDGHPLTSSDKV--LILPGGRVLQIPRAKVEDAGRYTCVAVNEAG 2856
Query: 361 EDTAAFLVTVTAPP 374
ED+ + V V PP
Sbjct: 2857 EDSLQYDVRVLVPP 2870
Score = 69.7 bits (163), Expect = 5e-11
Identities = 58/253 (22%), Positives = 101/253 (39%), Gaps = 12/253 (4%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGH--SNYSELSDVLTVSSDRASQEP 184
W++ P++ + + L+ H Q + ++D G ++ + D + P
Sbjct: 2327 WMKDGHPLIKAKGVEI--LDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2384
Query: 185 PVFI---KRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P I + E+++ +E + V SGIP P+ WFKD + + S I + +
Sbjct: 2385 PSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILS--GGRM 2442
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L Q D G+ C N G L + P + ED + E +++ L
Sbjct: 2443 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKE-KQSVTLT 2501
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G P P I W DG P+ D+ I +F L+I + + G Y A + G
Sbjct: 2502 CEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVPHTGRYTCLASSPAGH 2559
Query: 362 DTAAFLVTVTAPP 374
+ +F + V P
Sbjct: 2560 KSRSFSLNVFVSP 2572
Score = 69.7 bits (163), Expect = 5e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 3067 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 3124
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 3125 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 3182
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 3183 TIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 3242
Query: 371 TAPP 374
PP
Sbjct: 3243 QVPP 3246
Score = 68.9 bits (161), Expect = 9e-11
Identities = 65/246 (26%), Positives = 96/246 (39%), Gaps = 15/246 (6%)
Query: 152 QFRVAALNDVG--HSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
+ + ND G H S S QEPP ++ + +V + +
Sbjct: 577 ELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P IAW +D I S R +T+D L P D G C A+N G
Sbjct: 637 GYPKPKIAWTVNDMFIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQN 693
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
+ L APKL + LL + + ++ G P P ++W G + I
Sbjct: 694 STLRYIEAPKLMV---VQSELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLI 749
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNVSVTRQV 386
I P +LKI + D G+Y A N G T + V +PP P +VS+ ++
Sbjct: 750 -IDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSM--EI 806
Query: 387 DKSVTL 392
+VTL
Sbjct: 807 GSNVTL 812
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 3987 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 4044
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 4045 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 4101
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 4102 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSS 4158
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 4159 STSTKLTVHVPP 4170
Score = 68.5 bits (160), Expect = 1e-10
Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 1143
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 1200
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 1201 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 1259 QEPPTVEDLEPPYNTTFQERV 1279
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 3631 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3688
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 3689 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 3745
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 3746 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 3803
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 3804 PPSIAPGPTNMTVIVNVQTTLACE 3827
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 3891 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 3950
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 3951 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 4005
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 4006 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 4063
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 4064 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 4123
Query: 413 YR 414
R
Sbjct: 4124 IR 4125
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 1884
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1942
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1943 KAAGNPVPVITWYKDN--CLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 2001 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 2034
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 4347 KEPPVFKGDYPSNWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 4405
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 4406 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 4459
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 4460 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 4516
Query: 360 G 360
G
Sbjct: 4517 G 4517
Score = 61.7 bits (143), Expect = 1e-08
Identities = 46/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 1666 AGNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 1723
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG I D+R
Sbjct: 1724 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLI--DERDG 1780
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 1781 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP 1826
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 3713 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 3772
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 3773 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 3828
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 3829 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 3886
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 3887 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 3918
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/190 (27%), Positives = 78/190 (41%), Gaps = 17/190 (8%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 990 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPEGEE 1045
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPK-------LRYPRQYEDGLLYEINETIFLKTTI 304
GE CTATN G+A K +L + P+ L + E +L E + L +
Sbjct: 1046 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQDKPVEISVL--AGEEVTLPCEV 1103
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P P I W + +I+ + P S +KI + SD G Y A NI G T
Sbjct: 1104 KSLPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQ 1161
Query: 365 AFLVTVTAPP 374
A + V PP
Sbjct: 1162 AVKLNVHVPP 1171
Score = 55.2 bits (127), Expect = 1e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 4316
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 4317 ERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPV--FKGDYPSNWIEPLGGNAILNCEV 4374
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 4375 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 4431
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 4432 SMSLTLQSPP 4441
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/223 (25%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 1709 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 1761
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD I R + L+ Q S+ G +C A N G +
Sbjct: 1762 PPPTIMWLKDGQLI--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFE 1819
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 1820 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 1876
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 1877 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 792 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 851
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 909
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 910 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 966
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 967 GTNNKTTSVVVHVLP 981
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 4180 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 4237
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 4238 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 4294
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 4295 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPP 4350
Score = 39.5 bits (88), Expect = 0.063
Identities = 38/158 (24%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 237 ESTSVLL-FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
ES SV L ++ SDEG +C A + G + + P + Q + +
Sbjct: 478 ESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVI---QVPNNVTVTPG 534
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E L I+ + W+ + + + I S L++ S K +D GEY
Sbjct: 535 ERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LELKSVKFNDAGEYHCMV 593
Query: 356 KNIIGEDTAAFLVTVTAPPD---PPRNVSVTRQVDKSV 390
+ G A+ +TV PP P+N S T + S+
Sbjct: 594 SSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 85.0 bits (201), Expect = 1e-15
Identities = 54/194 (27%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 184 PPVFIKRLEDVT---ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
PPV IK E VT L N G PSP I W+KD+ ++ S + I T +
Sbjct: 429 PPV-IKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES--STIQTVNNGR 485
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + P D G C A N G + + + P + + + + +N + L
Sbjct: 486 ILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-IGTNFPNEVSVVLNRDVAL 544
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G P P I W DG P+ D + + + VL + +A+R+D+G YQ N G
Sbjct: 545 ECQVKGTPFPDIHWFKDGKPLFLGDP-NVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 603
Query: 361 EDTAAFLVTVTAPP 374
+ +T+ PP
Sbjct: 604 KQAKDIKLTIYIPP 617
Score = 78.6 bits (185), Expect = 1e-13
Identities = 57/199 (28%), Positives = 86/199 (43%), Gaps = 11/199 (5%)
Query: 182 QEPPVFIKRLE---DVTALE---NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
QEPP ++ LE + T E N ++EF G P PTI W + E+ + R I+
Sbjct: 330 QEPPT-VEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGREL-TGREPGISI 387
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
E ++L+ + P D GE C A N G K L + P ++ Q + + +N
Sbjct: 388 LEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTN-VSVLLN 446
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ L + G P+P I W D + I+ + +LK+ A D G Y +A
Sbjct: 447 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGR--ILKLFRATPEDAGRYSCKA 504
Query: 356 KNIIGEDTAAFLVTVTAPP 374
NI G F + V PP
Sbjct: 505 INIAGTSQKYFNIDVLVPP 523
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D++ L N ++ G+P P I W+KD I SS + A+ D+ L + SD
Sbjct: 627 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQ-ALYIDKG-QYLHIPRAQVSDS 684
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C N G A + + P + I ++ L+ G P+P +
Sbjct: 685 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPIL 744
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG P+ +D I I K L+I SA+ DRG+Y A ++ GE + V V
Sbjct: 745 TWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 802
Query: 373 PP 374
PP
Sbjct: 803 PP 804
Score = 72.5 bits (170), Expect = 7e-12
Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
V + N+ V GIP+P++ W KD + SS + +L SD G
Sbjct: 1092 VAVVVNNPVRLECEARGIPAPSLTWLKDGSPV-SSFSNGLQVLSGGRILALTSAQISDTG 1150
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G L + P + Q L+ + E + I P PT+
Sbjct: 1151 RYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAI---PPPTLT 1207
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
W DGHP++ + +SI+ SVLKI A+ D G Y +A N+ G
Sbjct: 1208 WLKDGHPLLK--KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 71.3 bits (167), Expect = 2e-11
Identities = 51/182 (28%), Positives = 71/182 (39%), Gaps = 4/182 (2%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V+ + N V G P P I WFKD +F D VL +D+
Sbjct: 533 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG-QVLHLKNARRNDK 591
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G +CT +N G +L + P ++ D + IN I L+ G P P I
Sbjct: 592 GRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTD-ISVLINSLIKLECETRGLPMPAI 650
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W DG PI++ + K L I A+ SD Y N+ G +F V V
Sbjct: 651 TWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYV 708
Query: 373 PP 374
PP
Sbjct: 709 PP 710
Score = 66.1 bits (154), Expect = 6e-10
Identities = 51/201 (25%), Positives = 81/201 (40%), Gaps = 16/201 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 159 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 214
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C A N G+ +L + PK++ ++ L ++ + + + G P P
Sbjct: 215 DSGMYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKH---LKVQVGQRVDIPCNAQGTPLP 271
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
I W G ++ D +S P L I A SD G Y A NI G D + V
Sbjct: 272 VITWSKGGSTMLVDGEHHVS-NPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITLHV 329
Query: 371 TAPP-----DPPRNVSVTRQV 386
PP +PP N + +V
Sbjct: 330 QEPPTVEDLEPPYNTTFQERV 350
Score = 65.3 bits (152), Expect = 1e-09
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 7/214 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + L + ++ V +GIP+P+I W KDD + ++ + + S VL
Sbjct: 897 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPV-NTAQGNLKIQSSGRVLQ 955
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR-YPRQYEDGLLYEINETIFLKT 302
+ L D G C ATN G +L + P L + + +L ++ + L+
Sbjct: 956 IAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVL--VSNPVQLEC 1013
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W D + ++ + ++ I SA+ SD G Y+ A N G
Sbjct: 1014 KAAGNPVPVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGAT 1071
Query: 363 TAAFLVTV-TAPPDPPRNVSVTRQVDKSVTLDWE 395
+ + V AP N V V+ V L+ E
Sbjct: 1072 ELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECE 1105
Score = 65.3 bits (152), Expect = 1e-09
Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 11/205 (5%)
Query: 183 EPPVF--IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
EPP ++ + T L ++ V+ +G P P I W+KD+ + S T++T
Sbjct: 988 EPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGS--TSMTFLNRGQ 1045
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
++ SD G KC A N G L + AP + + +N + L
Sbjct: 1046 IIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNM---VAVVVNNPVRL 1102
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ G P P++ W DG P+ + + + +L + SA+ SD G Y A N G
Sbjct: 1103 ECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 1161
Query: 361 EDTAAFLVTVTAPPD---PPRNVSV 382
E + V PP+ +NVSV
Sbjct: 1162 EKQRDIDLRVYVPPNIMGEEQNVSV 1186
Score = 62.5 bits (145), Expect = 8e-09
Identities = 45/166 (27%), Positives = 69/166 (41%), Gaps = 5/166 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G PSP + W KD + ++ I ++ Q + D G+ C AT+ G
Sbjct: 737 AGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI--DRGQYICVATSVAGEKEI 794
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
K + + P + + + +N + L + G P PTI W DG + D+R
Sbjct: 795 KYEVDVLVPPAIEGGDE-TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQ--LVDERDG 851
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I L I A+ S+ G Y+ A N G+ F VTV PP
Sbjct: 852 FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKEEFEVTVHVPP 897
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 61 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 116
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 117 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 176
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 177 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVAINIAGNVTQAV 234
Query: 367 LVTVTAPP 374
+ V PP
Sbjct: 235 KLNVHVPP 242
Score = 54.0 bits (124), Expect = 3e-06
Identities = 55/223 (24%), Positives = 82/223 (36%), Gaps = 12/223 (5%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
Q+ A + G DVL + E FI + ++ L+ HVT G
Sbjct: 780 QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELD-----CHVT--GS 832
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P PTI W KD + R + L+ Q S+ G +C A N G +
Sbjct: 833 PPPTIMWLKDGQLV--DERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKEEFE 890
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ + P ++ E ++ + + L+ G P P+I W D P+ T + I
Sbjct: 891 VTVHVPPTIKSSGLSERVVVK--YKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKI 947
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
VL+I D G Y A N GE + V PP
Sbjct: 948 QSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 990
Score = 45.6 bits (103), Expect = 0.001
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + ++V+ L + VE IP PT+ W KD + + ++ ++ E+ SVL
Sbjct: 1174 PPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLL--KKPGLSISENRSVLK 1231
Query: 244 FHQILPSDEGEIKCTATNRGG 264
D G C ATN G
Sbjct: 1232 IEDAQVQDTGRYTCEATNVAG 1252
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 84.2 bits (199), Expect = 2e-15
Identities = 80/306 (26%), Positives = 124/306 (40%), Gaps = 27/306 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSV 241
PP + + +D A + V F G P P I W K+ ++ F S+ T S S
Sbjct: 346 PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSP 405
Query: 242 ---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE---IN 295
L + D G C A + G + KA L ++ A P G + +
Sbjct: 406 RGQLNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLG 465
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+++L + G P P++ W+ DG + DD ++ T L I + + D G Y A
Sbjct: 466 SSVWLPCRVTGNPQPSVRWKKDGQWLQGDD-LQFK-TMANGTLYIANVQEMDMGFYSCVA 523
Query: 356 KNIIGEDTAAFLVTVT----APPDPPRNVS----------VTRQVDKSVTLDWEPPADDG 401
K+ GE T + + + PDPP S VT S+TL W+P G
Sbjct: 524 KSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG 583
Query: 402 GCKVGNYIVEYYR-TGWNVWLKAITSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSS 459
V +Y++E + N W + T+ L + Y F ++A +G+S PS
Sbjct: 584 AA-VTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSP 642
Query: 460 ESSPVR 465
S PVR
Sbjct: 643 VSEPVR 648
Score = 69.3 bits (162), Expect = 7e-11
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 12/193 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++R + L + V F G P P + W K+D E+ + R I +D S L
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDHS---L 311
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ DEG C A N G A L + P+L Q +D + E++ +
Sbjct: 312 WIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQL--VTQPQDQMAAP-GESVAFQC 368
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKN 357
G P P I W+ +G ++ + T +FSV L I + +R D G Y QA +
Sbjct: 369 ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVS 428
Query: 358 IIGEDTAAFLVTV 370
+ G A L+ +
Sbjct: 429 VAGSILAKALLEI 441
Score = 49.6 bits (113), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 14/225 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT--AITTDESTSVL 242
P +++ D+ + G P P I W+K+ + + R A + L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 243 LFHQILPS-----DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
F +I+ DEG C A N G A ++ LE A RQ ++ + E
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASR-NASLEVAVLRDDFRQSPGNVVVAVGEP 182
Query: 298 IFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
L+ G P P++ WR DG + + E IT + L + +SD G Y A
Sbjct: 183 AVLECVPPRGHPEPSVSWRKDGARLKEE---EGRITIRGGKLMMSHTLKSDAGMYVCVAS 239
Query: 357 NIIG--EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPAD 399
N+ G E AA ++ + P R V+ D VT E D
Sbjct: 240 NMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGD 284
Score = 46.0 bits (104), Expect = 7e-04
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 13/167 (7%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P+++W KD + T +++ H L SD G C A+N G +
Sbjct: 192 GHPEPSVSWRKDGARL--KEEEGRITIRGGKLMMSHT-LKSDAGMYVCVASNMAGERESA 248
Query: 270 AR--LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
A + LE LR P +L + T + + G P P + WR + + T R
Sbjct: 249 AAEVMVLERPSFLRRP--VNQVVLADAPVTFLCE--VKGDPPPRLRWRKEDGELPTG-RY 303
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
EI L I D G Y A+N +G A+ ++V PP
Sbjct: 304 EIRSDHS---LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPP 347
Score = 42.7 bits (96), Expect = 0.007
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIVL 136
+PPG P P++++ N+ITL W P G A + Y +E + W A + L
Sbjct: 554 SPPGAPSQ-PVVTEITKNSITLTWKPNPQTGAA-VTSYVIEAFSPAAGNTWRTVADGVQL 611
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ 182
V +GL+P Y F V A+ G S S +S+ + S+
Sbjct: 612 ETHTV-SGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSR 656
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 83.8 bits (198), Expect = 3e-15
Identities = 80/306 (26%), Positives = 124/306 (40%), Gaps = 27/306 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSV 241
PP + + +D A + V F G P P I W K+ ++ F S+ T S S
Sbjct: 346 PPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSP 405
Query: 242 ---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE---IN 295
L + D G C A + G + KA L ++ A P G + +
Sbjct: 406 RGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLG 465
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+++L + G P P++ W+ DG + DD ++ T L I + + D G Y A
Sbjct: 466 SSVWLPCRVTGNPQPSVRWKKDGQWLQGDD-LQFK-TMANGTLYIANVQEMDMGFYSCVA 523
Query: 356 KNIIGEDTAAFLVTVT----APPDPPRNVS----------VTRQVDKSVTLDWEPPADDG 401
K+ GE T + + + PDPP S VT S+TL W+P G
Sbjct: 524 KSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG 583
Query: 402 GCKVGNYIVEYYR-TGWNVWLKAITSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSS 459
V +Y++E + N W + T+ L + Y F ++A +G+S PS
Sbjct: 584 AA-VTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSP 642
Query: 460 ESSPVR 465
S PVR
Sbjct: 643 VSEPVR 648
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 12/193 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++R + L + V F G P P + W K+D E+ + R I +D S L
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGEL-PTGRYEIRSDHS---L 311
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ DEG C A N G A L + P+L Q +D + E++ +
Sbjct: 312 WIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQL--VTQPQDQMAAP-GESVAFQC 368
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKN 357
G P P I W+ +G ++ + T +FSV L I + +R D G Y QA +
Sbjct: 369 ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVS 428
Query: 358 IIGEDTAAFLVTV 370
+ G A L+ +
Sbjct: 429 VAGSILAKALLEI 441
Score = 49.6 bits (113), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 14/225 (6%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT--AITTDESTSVL 242
P +++ D+ + G P P I W+K+ + + R A + L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 243 LFHQILPS-----DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
F +I+ DEG C A N G A ++ LE A RQ ++ + E
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASR-NASLEVAVLRDDFRQSPGNVVVAVGEP 182
Query: 298 IFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
L+ G P P++ WR DG + + E IT + L + +SD G Y A
Sbjct: 183 AVLECVPPRGHPEPSVSWRKDGARLKEE---EGRITIRGGKLMMSHTLKSDAGMYVCVAS 239
Query: 357 NIIG--EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPAD 399
N+ G E AA ++ + P R V+ D VT E D
Sbjct: 240 NMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGD 284
Score = 46.0 bits (104), Expect = 7e-04
Identities = 45/167 (26%), Positives = 67/167 (40%), Gaps = 13/167 (7%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P+++W KD + T +++ H L SD G C A+N G +
Sbjct: 192 GHPEPSVSWRKDGARL--KEEEGRITIRGGKLMMSHT-LKSDAGMYVCVASNMAGERESA 248
Query: 270 AR--LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
A + LE LR P +L + T + + G P P + WR + + T R
Sbjct: 249 AAEVMVLERPSFLRRP--VNQVVLADAPVTFLCE--VKGDPPPRLRWRKEDGELPTG-RY 303
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
EI L I D G Y A+N +G A+ ++V PP
Sbjct: 304 EIRSDHS---LWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPP 347
Score = 42.7 bits (96), Expect = 0.007
Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 4/106 (3%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIVL 136
+PPG P P++++ N+ITL W P G A + Y +E + W A + L
Sbjct: 554 SPPGAPSQ-PVVTEITKNSITLTWKPNPQTGAA-VTSYVIEAFSPAAGNTWRTVADGVQL 611
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQ 182
V +GL+P Y F V A+ G S S +S+ + S+
Sbjct: 612 ETHTV-SGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSR 656
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 83.8 bits (198), Expect = 3e-15
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 2/183 (1%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
DV+ L + VE +GIP+P I W KD I S I + S L + L SD
Sbjct: 293 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDT 352
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G+ C ATN G L + P +R + + L+ ++ +I ++ G P P I
Sbjct: 353 GKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 412
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
W +G P+ I + + V++I A+ SD Y A N G D + + V A
Sbjct: 413 NWLKNGLPLPLSSHIRLLAAGQ--VIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFA 470
Query: 373 PPD 375
PP+
Sbjct: 471 PPN 473
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 1/166 (0%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTIAW K+ I +S + S L + SD G C A+N G A
Sbjct: 214 TGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQK 273
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++ P + + + + E + L G PTP I+W DG PI + +
Sbjct: 274 YYFLSIQVPPSVA-GAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETER 332
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
I ++ S L I+ A SD G+Y A N GE+ F + V P
Sbjct: 333 IRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 378
Score = 79.8 bits (188), Expect = 5e-14
Identities = 55/212 (25%), Positives = 94/212 (44%), Gaps = 12/212 (5%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E++T L+ G P+P++AW +D + ++T LL + D
Sbjct: 481 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--ED 538
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
G+ C A+N G L + P + ++E+ + +N + L G P P
Sbjct: 539 SGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEE-ISVIVNNPLELTCIASGIPAPK 597
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D+++ VL+I +A+ D G Y A + G+D +LV V
Sbjct: 598 MTWMKDGRPLPQTDQVQT--LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVH 655
Query: 372 APP-----DPPRNVSVTRQVDKSVTLDWEPPA 398
PP D PR+++V R ++ VTL+ + A
Sbjct: 656 VPPNIAGTDEPRDITVLR--NRQVTLECKSDA 685
Score = 78.2 bits (184), Expect = 1e-13
Identities = 56/213 (26%), Positives = 93/213 (43%), Gaps = 9/213 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P V + E++T + N+ + SG P P ++W K++ I + T I T ++
Sbjct: 2 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 61
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
++ SD GE C A N+ G + K L + P ++ E + + E ++ L+
Sbjct: 62 RAKV--SDGGEYTCIAINQAGESKKKFSLTVYVPPSIK-DHDSESLSVVNVREGTSVSLE 118
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W +G I +EI + +L I A+ SD G+Y +A N+ G
Sbjct: 119 XESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVSDTGQYVCRAINVAGR 176
Query: 362 DTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
D F + V PP + P + + VTL
Sbjct: 177 DDKNFHLNVYVPPSIEGPEREVIVETISNPVTL 209
Score = 73.7 bits (173), Expect = 3e-12
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 15/208 (7%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L++ + + G+P P I W KD I S R + + S +
Sbjct: 1114 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 1173
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--IF 299
+ P D G C A N G + T +L + P++R + Y +NE
Sbjct: 1174 TF---VQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGH-----YTVNENSQAI 1225
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G PTP I W+ D ++ + + + L + + D G Y A N
Sbjct: 1226 LPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAA 1283
Query: 360 GEDTAAFLVTVTAPP---DPPRNVSVTR 384
GEDT +TV P + P +VS+ +
Sbjct: 1284 GEDTHTVSLTVHVLPTFTELPGDVSLNK 1311
Score = 70.1 bits (164), Expect = 4e-11
Identities = 48/184 (26%), Positives = 75/184 (40%), Gaps = 4/184 (2%)
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPS 250
L V E V + +P P I W+K+ I S I D +L + S
Sbjct: 104 LSVVNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQ--MLHIKKAEVS 161
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G+ C A N G L + P + P + + ++ I+ + L G P P
Sbjct: 162 DTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPER--EVIVETISNPVTLTCDATGIPPP 219
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
TI W + I D +E+ I S L+I ++ SD G Y A N+ G+ + +++
Sbjct: 220 TIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSI 279
Query: 371 TAPP 374
PP
Sbjct: 280 QVPP 283
Score = 68.9 bits (161), Expect = 9e-11
Identities = 50/192 (26%), Positives = 81/192 (42%), Gaps = 8/192 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPPV + ++ + N+ + +G PSP I W K+ + +S R + L
Sbjct: 1024 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVL--PSGGL 1081
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G C A N G A+ K +L ++ P + P E + +++ I L
Sbjct: 1082 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVIS-PHLKE--YVIAVDKPITLSC 1138
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P P I W DG I+ R + + L+I + D G Y A N+ G
Sbjct: 1139 EADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQITFVQPGDAGHYTCMAANVAGSS 1195
Query: 363 TAAFLVTVTAPP 374
+ + +TV PP
Sbjct: 1196 STSTKLTVHVPP 1207
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 8/204 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
D+T L N +V +P P I W ++ + ++ R I + L + D
Sbjct: 668 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 725
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
C A+N G + L + P ++ Q L+ +N++ L+ G PTP I
Sbjct: 726 ANYTCVASNIAGKTTREFILTVNVPPNIKGGPQ---SLVILLNKSTVLECIAEGVPTPRI 782
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
WR DG ++ + SI L I SA +D G Y A N G D + V
Sbjct: 783 TWRKDG-AVLAGNHARYSILEN-GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHV 840
Query: 373 PPD-PPRNVSVTRQVDKSVTLDWE 395
PP P ++T V+ TL E
Sbjct: 841 PPSIAPGPTNMTVIVNVQTTLACE 864
Score = 67.7 bits (158), Expect = 2e-10
Identities = 67/242 (27%), Positives = 91/242 (37%), Gaps = 12/242 (4%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D Q PP D ++ T SG+P P+I W K+ +
Sbjct: 928 DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSS 987
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
+L Q+ + G C A N G A L + P ++ P+ E L +N
Sbjct: 988 GAIEILATQL--NHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQ-PQPSE--LHVILNNP 1042
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
I L G P+P I W+ +G + T R ++ P L+I A R D G Y A+N
Sbjct: 1043 ILLPCEATGTPSPFITWQKEGINVNTSGR-NHAVLPS-GGLQISRAVREDAGTYMCVAQN 1100
Query: 358 IIGEDTAAFLVTVTAPP-DPPRNVSVTRQVDKSVTLDWE----PPADDGGCKVGNYIVEY 412
G + V PP P VDK +TL E PP D K G IVE
Sbjct: 1101 PAGTALGKIKLNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVES 1160
Query: 413 YR 414
R
Sbjct: 1161 IR 1162
Score = 63.7 bits (148), Expect = 3e-09
Identities = 49/181 (27%), Positives = 78/181 (43%), Gaps = 12/181 (6%)
Query: 182 QEPPVFIKRLED--VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+EPPVF + L + + + G P+PTI W + +I S R + S
Sbjct: 1384 KEPPVFKGDYPSHWIEPLGGNAI-LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL 1442
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
++ + + D G+ C ATN G L L++ P + E + I
Sbjct: 1443 AI---YGTVNEDAGDYTCVATNEAGVVERSMSLTLQSPPIITL-EPVET--VINAGGKII 1496
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L G+P PTI W GH I DDR+ + + L I A++ D E++ A+N++
Sbjct: 1497 LNCQATGEPQPTITWSRQGHSISWDDRVNVLSN---NSLYIADAQKEDTSEFECVARNLM 1553
Query: 360 G 360
G
Sbjct: 1554 G 1554
Score = 58.4 bits (135), Expect = 1e-07
Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 10/212 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP + + L N G+P+P I W KD + + R +I + +
Sbjct: 750 PPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQ 809
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
H +D G C ATN G + L + P + P ++ + T+ +
Sbjct: 810 SAHV---TDTGRYLCMATNAAGTDRRRIDLQVHVPPSIA-PGPTNMTVIVNVQTTLACEA 865
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
T G P P+I WR +GH + D L I S D Y+ N G+D
Sbjct: 866 T--GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDD 923
Query: 363 TAAFLVTVTAPP---DPPRNVSVTRQVDKSVT 391
+TV PP D P + VT+ +T
Sbjct: 924 KRTVDLTVQVPPSIADEPTDFLVTKHAPAVIT 955
Score = 58.0 bits (134), Expect = 2e-07
Identities = 45/183 (24%), Positives = 76/183 (41%), Gaps = 5/183 (2%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E + L + + +G P P I W K+ + S + ++ Q+ SD
Sbjct: 388 EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQV--SD 445
Query: 252 EGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
C A+NR G L + A P + E+ + + + T T G P P+
Sbjct: 446 VAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT-DGTPAPS 504
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
+ W DG P+ D ++++ VL++ A+ D G+Y A N GE + F++ V
Sbjct: 505 MAWLRDGQPLGLD--AHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVL 562
Query: 372 APP 374
PP
Sbjct: 563 EPP 565
Score = 53.6 bits (123), Expect = 4e-06
Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 9/190 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F + DV+ + +++ +GIP P + W ++ I + ++ S L+
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVI 1353
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
++ D G CTA N G + ++ P + Y + + L +
Sbjct: 1354 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPV--FKGDYPSHWIEPLGGNAILNCEV 1411
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G PTPTI+W G I RI L I+ D G+Y A N G
Sbjct: 1412 KGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCVATNEAGVVER 1468
Query: 365 AFLVTVTAPP 374
+ +T+ +PP
Sbjct: 1469 SMSLTLQSPP 1478
Score = 48.8 bits (111), Expect = 1e-04
Identities = 43/180 (23%), Positives = 61/180 (33%), Gaps = 9/180 (5%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
T EN + GIP+P I W KD+ + + T E L+ ++ D G
Sbjct: 1217 TVNENSQAILPCVADGIPTPAINWKKDN--VLLANLLGKYTAEPYGELILENVVLEDSGF 1274
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW 314
C A N G L + P + + E + L G P P + W
Sbjct: 1275 YTCVANNAAGEDTHTVSLTVHVLPTFT---ELPGDVSLNKGEQLRLSCKATGIPLPKLTW 1331
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + I S L I + D G Y A+N +G A V V PP
Sbjct: 1332 TFNNNIIPA----HFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPP 1387
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 83.4 bits (197), Expect = 4e-15
Identities = 54/200 (27%), Positives = 87/200 (43%), Gaps = 4/200 (2%)
Query: 266 AVTKARLCLEAAPKLRYPRQ---YEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII 322
A K + + PK P Q + + E++ L + G T W I
Sbjct: 298 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 357
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
+ +++ + S L I + ++ G Y + +N G A ++V PDPP
Sbjct: 358 ESEHMKVENSENGSKLTILAGRQEHCGCYTLLVENKSGSRQAQVNLSVVDKPDPPAGTPC 417
Query: 383 TRQV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSE 441
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ E
Sbjct: 418 ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 477
Query: 442 YKFRIKAESPYGMSAPSSES 461
YKFR++A + YG S PS ES
Sbjct: 478 YKFRVRAINVYGTSEPSQES 497
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 886 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 945
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 946 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 977
Score = 55.6 bits (128), Expect = 9e-07
Identities = 40/146 (27%), Positives = 67/146 (45%), Gaps = 10/146 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 409 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 466
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
+ L P H+Y+FRV A+N G S S+ S++ TV +EP ++V ++
Sbjct: 467 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--EKPEEPK------DEVEVSDD 518
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEI 225
D+ E V + + T D Y+I
Sbjct: 519 DEKEPEVDYRTVTINTEQKVSDFYDI 544
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/94 (26%), Positives = 43/94 (45%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P F ++L+DV E K+ S P TI W + + +++ ++ + S +
Sbjct: 176 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 235
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
+ LP D G KC A N G A ++ ++ AP
Sbjct: 236 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 269
Score = 35.5 bits (78), Expect = 1.0
Identities = 23/77 (29%), Positives = 33/77 (42%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ L+ + P TI W +G + T I +S + I A DRG Y+ AKN
Sbjct: 193 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 252
Query: 358 IIGEDTAAFLVTVTAPP 374
G+ + VTV P
Sbjct: 253 DAGQAECSCQVTVDDAP 269
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 83.0 bits (196), Expect = 5e-15
Identities = 75/287 (26%), Positives = 122/287 (42%), Gaps = 18/287 (6%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-----AITTDESTSV 241
I +E+ TA+E ++V SG P P+I W I S +T + + S
Sbjct: 310 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I +D GE CTA+N G L ++ APKL+ P +E N+ + +
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YTWEGNQ-VNIT 425
Query: 302 TTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ P+ TI W DG P I+I TP S L++ +D G Y A N I
Sbjct: 426 CEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 485
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
G+++ F++ P P ++ + + ++ P GG + Y E+ G V
Sbjct: 486 GQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEV 544
Query: 420 W-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 545 WHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 591
Score = 73.3 bits (172), Expect = 4e-12
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 13/200 (6%)
Query: 184 PPVFIKRLEDVTALEN--DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDEST 239
PP R V A N V G P PT++W KD +I I +D+S
Sbjct: 211 PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS- 269
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L ++ +DE E C A N+ G L + A PK+ Y E+ E+ E +
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAMELEEQVT 326
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEYQIQ 354
L G P P+I WR I ++++ + + + S L + S + +D GEY
Sbjct: 327 LTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICT 386
Query: 355 AKNIIGEDTAAFLVTVTAPP 374
A N IG+D+ + + V P
Sbjct: 387 ASNTIGQDSQSMYLEVQYAP 406
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 216 IAWFKDDYEIFS---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+WF + E + R + + D+S+S L + D G KC T G + ++A +
Sbjct: 52 ISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDG-SESEATV 110
Query: 273 CLEAAPKLRY-----PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ KL + P+++ +G E + +V PTI W+H G +I +
Sbjct: 111 NVKIFQKLMFKNAPTPQEFREG------EDAVIVCDVVSSLPPTIIWKHKGRDVILKKDV 164
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNII-GE-DTAAFLVTVTAPP--DPPRN-VSV 382
+ + L+I K++D G Y+ + + + GE + V V PP +N V+
Sbjct: 165 RFIVLSN-NYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNA 223
Query: 383 TRQVDKSVTL 392
T + +SVTL
Sbjct: 224 TANLGQSVTL 233
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 497 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 551
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 552 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 595
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 83.0 bits (196), Expect = 5e-15
Identities = 75/287 (26%), Positives = 122/287 (42%), Gaps = 18/287 (6%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-----AITTDESTSV 241
I +E+ TA+E ++V SG P P+I W I S +T + + S
Sbjct: 310 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I +D GE CTA+N G L ++ APKL+ P +E N+ + +
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YTWEGNQ-VNIT 425
Query: 302 TTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ P+ TI W DG P I+I TP S L++ +D G Y A N I
Sbjct: 426 CEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 485
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
G+++ F++ P P ++ + + ++ P GG + Y E+ G V
Sbjct: 486 GQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEV 544
Query: 420 W-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 545 WHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 591
Score = 73.3 bits (172), Expect = 4e-12
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 13/200 (6%)
Query: 184 PPVFIKRLEDVTALEN--DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDEST 239
PP R V A N V G P PT++W KD +I I +D+S
Sbjct: 211 PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS- 269
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L ++ +DE E C A N+ G L + A PK+ Y E+ E+ E +
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAMELEEQVT 326
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEYQIQ 354
L G P P+I WR I ++++ + + + S L + S + +D GEY
Sbjct: 327 LTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICT 386
Query: 355 AKNIIGEDTAAFLVTVTAPP 374
A N IG+D+ + + V P
Sbjct: 387 ASNTIGQDSQSMYLEVQYAP 406
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 216 IAWFKDDYEIFS---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+WF + E + R + + D+S+S L + D G KC T G + ++A +
Sbjct: 52 ISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDG-SESEATV 110
Query: 273 CLEAAPKLRY-----PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ KL + P+++ +G E + +V PTI W+H G +I +
Sbjct: 111 NVKIFQKLMFKNAPTPQEFREG------EDAVIVCDVVSSLPPTIIWKHKGRDVILKKDV 164
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNII-GE-DTAAFLVTVTAPP--DPPRN-VSV 382
+ + L+I K++D G Y+ + + + GE + V V PP +N V+
Sbjct: 165 RFIVLSN-NYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNA 223
Query: 383 TRQVDKSVTL 392
T + +SVTL
Sbjct: 224 TANLGQSVTL 233
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 497 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 551
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 552 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 595
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 83.0 bits (196), Expect = 5e-15
Identities = 75/287 (26%), Positives = 122/287 (42%), Gaps = 18/287 (6%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-----AITTDESTSV 241
I +E+ TA+E ++V SG P P+I W I S +T + + S
Sbjct: 391 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 450
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I +D GE CTA+N G L ++ APKL+ P +E N+ + +
Sbjct: 451 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YTWEGNQ-VNIT 506
Query: 302 TTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ P+ TI W DG P I+I TP S L++ +D G Y A N I
Sbjct: 507 CEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 566
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
G+++ F++ P P ++ + + ++ P GG + Y E+ G V
Sbjct: 567 GQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEV 625
Query: 420 W-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 626 WHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 672
Score = 73.3 bits (172), Expect = 4e-12
Identities = 57/200 (28%), Positives = 86/200 (43%), Gaps = 13/200 (6%)
Query: 184 PPVFIKRLEDVTALEN--DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDEST 239
PP R V A N V G P PT++W KD +I I +D+S
Sbjct: 292 PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS- 350
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L ++ +DE E C A N+ G L + A PK+ Y E+ E+ E +
Sbjct: 351 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAMELEEQVT 407
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEYQIQ 354
L G P P+I WR I ++++ + + + S L + S + +D GEY
Sbjct: 408 LTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICT 467
Query: 355 AKNIIGEDTAAFLVTVTAPP 374
A N IG+D+ + + V P
Sbjct: 468 ASNTIGQDSQSMYLEVQYAP 487
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 216 IAWFKDDYEIFS---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+WF + E + R + + D+S+S L + D G KC T G + ++A +
Sbjct: 133 ISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDG-SESEATV 191
Query: 273 CLEAAPKLRY-----PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ KL + P+++ +G E + +V PTI W+H G +I +
Sbjct: 192 NVKIFQKLMFKNAPTPQEFREG------EDAVIVCDVVSSLPPTIIWKHKGRDVILKKDV 245
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNII-GE-DTAAFLVTVTAPP--DPPRN-VSV 382
+ + L+I K++D G Y+ + + + GE + V V PP +N V+
Sbjct: 246 RFIVLSN-NYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNA 304
Query: 383 TRQVDKSVTL 392
T + +SVTL
Sbjct: 305 TANLGQSVTL 314
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 578 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 632
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 633 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 676
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 82.6 bits (195), Expect = 7e-15
Identities = 75/287 (26%), Positives = 122/287 (42%), Gaps = 18/287 (6%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT-----AITTDESTSV 241
I +E+ TA+E ++V SG P P+I W I S +T + + S
Sbjct: 310 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSS 369
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L I +D GE CTA+N G L ++ APKL+ P +E N+ + +
Sbjct: 370 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YTWEGNQ-VNIT 425
Query: 302 TTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ P+ TI W DG P I+I TP S L++ +D G Y A N I
Sbjct: 426 CEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRI 485
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV 419
G+++ F++ P P ++ + + ++ P GG + Y E+ G V
Sbjct: 486 GQESFEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEV 544
Query: 420 W-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
W K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 545 WHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 591
Score = 70.1 bits (164), Expect = 4e-11
Identities = 56/200 (28%), Positives = 85/200 (42%), Gaps = 13/200 (6%)
Query: 184 PPVFIKRLEDVTALEN--DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDEST 239
PP R V A N V P PT++W KD +I I +D+S
Sbjct: 211 PPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS- 269
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L ++ +DE E C A N+ G L + A PK+ Y E+ E+ E +
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAMELEEQVT 326
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDR-----IEISITPKFSVLKIHSAKRSDRGEYQIQ 354
L G P P+I WR I ++++ + + + S L + S + +D GEY
Sbjct: 327 LTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICT 386
Query: 355 AKNIIGEDTAAFLVTVTAPP 374
A N IG+D+ + + V P
Sbjct: 387 ASNTIGQDSQSMYLEVQYAP 406
Score = 51.6 bits (118), Expect = 1e-05
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 216 IAWFKDDYEIFS---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+WF + E + R + + D+S+S L + D G KC T G + ++A +
Sbjct: 52 ISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDG-SESEATV 110
Query: 273 CLEAAPKLRY-----PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ KL + P+++ +G E + +V PTI W+H G +I +
Sbjct: 111 NVKIFQKLMFKNAPTPQEFREG------EDAVIVCDVVSSLPPTIIWKHKGRDVILKKDV 164
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNII-GE-DTAAFLVTVTAPPD--PPRN-VSV 382
+ + L+I K++D G Y+ + + + GE + V V PP +N V+
Sbjct: 165 RFIVLSN-NYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIRARQNIVNA 223
Query: 383 TRQVDKSVTL 392
T + +SVTL
Sbjct: 224 TANLGQSVTL 233
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 497 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 551
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 552 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 595
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 82.6 bits (195), Expect = 7e-15
Identities = 90/322 (27%), Positives = 129/322 (40%), Gaps = 30/322 (9%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE--I 225
E S LTV + + PP F+ R D + V F G P P + W K+ + +
Sbjct: 20 EASATLTVRARPVA--PPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLL 77
Query: 226 FSSRRTAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY 282
F ++ + S S L I SD G C A G + KA+L + R
Sbjct: 78 FPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRP 137
Query: 283 PRQYEDGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVL 338
P G + ++ T LK G P P I W +G D R I + L
Sbjct: 138 PPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTL 194
Query: 339 KIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-------------PDPPRNVSVTRQ 385
+I + + SD G Y A + GE + + ++ VT P PP VT
Sbjct: 195 QIKNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDV 254
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYY-RTGWNVWLKAITSRKTNV-TLFDLIEGSEYK 443
SVTL W+P G YI+E + ++ N W KT + T+ L + Y
Sbjct: 255 TKNSVTLSWQP-GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYL 313
Query: 444 FRIKAESPYGMSAPSSESSPVR 465
F ++A +P G+S PS S PVR
Sbjct: 314 FMVRAINPQGLSDPSPMSDPVR 335
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P PP KPQ+ +D N++TL W P T G P Y +E ++ S W +T V
Sbjct: 243 PGPPSKPQV----TDVTKNSVTLSWQPGT-PGTLPASAYIIEAFSQSVSNSW-QTVANHV 296
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL P Y F V A+N G S+ S +SD
Sbjct: 297 KTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 332
Score = 39.9 bits (89), Expect = 0.048
Identities = 38/157 (24%), Positives = 65/157 (41%), Gaps = 15/157 (9%)
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFLKTTIV 305
+ +DEG C A NR G A L + A P ++ + D ++ + T+
Sbjct: 1 MSTDEGTYMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQ-GRTVTFPCETK 59
Query: 306 GKPTPTIEWRHDG--------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
G P P + W+ +G P + R +S T ++ I +RSD G Y QA
Sbjct: 60 GNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI---QRSDAGYYICQALT 116
Query: 358 IIGEDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLD 393
+ G A + VT D P + + ++++ +D
Sbjct: 117 VAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 153
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 82.6 bits (195), Expect = 7e-15
Identities = 45/138 (32%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR 384
+ I++ + S L I +A++ G Y + +N +G A +TV PDPP
Sbjct: 2 EHIKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS 61
Query: 385 QV-DKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
+ S+TL W + DGG V +Y +E + + W + T R T+ + DL+ EYK
Sbjct: 62 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYK 121
Query: 444 FRIKAESPYGMSAPSSES 461
FR++A + YG S PS ES
Sbjct: 122 FRVRAINVYGTSEPSQES 139
Score = 56.0 bits (129), Expect = 7e-07
Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 455 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 514
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A +E
Sbjct: 515 ISDVCGDDDAKYTCKAVNSLGEATCTAEHIVE 546
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P P SD +++TL W +++DGG+ ++ Y +E + W A
Sbjct: 51 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTS 108
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV 175
+ L P H+Y+FRV A+N G S S+ S++ TV
Sbjct: 109 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTV 144
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 81.8 bits (193), Expect = 1e-14
Identities = 86/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE--IFSSRR 230
+ S+ + PP F+ R D + V F G P P + W K+ + +F ++
Sbjct: 302 MEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP 361
Query: 231 TAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE 287
+ S S L I SD G C A G + KA+L + R P
Sbjct: 362 QQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIL 421
Query: 288 DGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSA 343
G + ++ T LK G P P I W +G D R I + L+I +
Sbjct: 422 QGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTLQIKNL 478
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-------------PDPPRNVSVTRQVDKSV 390
+ SD G Y A + GE + + ++ VT P PP VT SV
Sbjct: 479 RISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSV 538
Query: 391 TLDWEPPADDGGCKVGNYIVEYY-RTGWNVWLKAITSRKTNV-TLFDLIEGSEYKFRIKA 448
TL W+P G YI+E + ++ N W KT + T+ L + Y F ++A
Sbjct: 539 TLSWQP-GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRA 597
Query: 449 ESPYGMSAPSSESSPVR 465
+P G+S PS S PVR
Sbjct: 598 INPQGLSDPSPMSDPVR 614
Score = 70.1 bits (164), Expect = 4e-11
Identities = 59/220 (26%), Positives = 95/220 (43%), Gaps = 19/220 (8%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++R + LE + VEF G P PT+ W KDD ++ R D+ T L
Sbjct: 223 ERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYD--IKDDYT--L 278
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +DEG C A NR G A L + A P ++ + D ++ + T+
Sbjct: 279 RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP--QFVVRPRDQIVAQ-GRTVTFPC 335
Query: 303 TIVGKPTPTIEWRHDG--------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
G P P + W+ +G P + R +S T ++ I +RSD G Y Q
Sbjct: 336 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI---QRSDAGYYICQ 392
Query: 355 AKNIIGEDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLD 393
A + G A + VT D P + + ++++ +D
Sbjct: 393 ALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432
Score = 60.9 bits (141), Expect = 2e-08
Identities = 56/197 (28%), Positives = 84/197 (42%), Gaps = 14/197 (7%)
Query: 175 VSSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD------DYEIF 226
V R QE PP ++ DV + + + G P+PTI W+KD D +
Sbjct: 19 VDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDP 78
Query: 227 SSRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S R + + + + H + DEG C A N G AV++ LE A RQ
Sbjct: 79 RSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR-NASLEVALLRDDFRQ 137
Query: 286 YEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAK 344
++ E L+ G P PTI W+ D + DD+ E I+ + L I + +
Sbjct: 138 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDK-EERISIRGGKLMISNTR 194
Query: 345 RSDRGEYQIQAKNIIGE 361
+SD G Y N++GE
Sbjct: 195 KSDAGMYTCVGTNMVGE 211
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P PP KPQ+ +D N++TL W P T G P Y +E ++ S W +T V
Sbjct: 522 PGPPSKPQV----TDVTKNSVTLSWQPGT-PGTLPASAYIIEAFSQSVSNSW-QTVANHV 575
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL P Y F V A+N G S+ S +SD
Sbjct: 576 KTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 611
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 81.8 bits (193), Expect = 1e-14
Identities = 86/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE--IFSSRR 230
+ S+ + PP F+ R D + V F G P P + W K+ + +F ++
Sbjct: 318 MEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP 377
Query: 231 TAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE 287
+ S S L I SD G C A G + KA+L + R P
Sbjct: 378 QQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIL 437
Query: 288 DGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSA 343
G + ++ T LK G P P I W +G D R I + L+I +
Sbjct: 438 QGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTLQIKNL 494
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-------------PDPPRNVSVTRQVDKSV 390
+ SD G Y A + GE + + ++ VT P PP VT SV
Sbjct: 495 RISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSV 554
Query: 391 TLDWEPPADDGGCKVGNYIVEYY-RTGWNVWLKAITSRKTNV-TLFDLIEGSEYKFRIKA 448
TL W+P G YI+E + ++ N W KT + T+ L + Y F ++A
Sbjct: 555 TLSWQP-GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRA 613
Query: 449 ESPYGMSAPSSESSPVR 465
+P G+S PS S PVR
Sbjct: 614 INPQGLSDPSPMSDPVR 630
Score = 70.1 bits (164), Expect = 4e-11
Identities = 59/220 (26%), Positives = 95/220 (43%), Gaps = 19/220 (8%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++R + LE + VEF G P PT+ W KDD ++ R D+ T L
Sbjct: 239 ERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYD--IKDDYT--L 294
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +DEG C A NR G A L + A P ++ + D ++ + T+
Sbjct: 295 RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP--QFVVRPRDQIVAQ-GRTVTFPC 351
Query: 303 TIVGKPTPTIEWRHDG--------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
G P P + W+ +G P + R +S T ++ I +RSD G Y Q
Sbjct: 352 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI---QRSDAGYYICQ 408
Query: 355 AKNIIGEDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLD 393
A + G A + VT D P + + ++++ +D
Sbjct: 409 ALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 448
Score = 59.7 bits (138), Expect = 6e-08
Identities = 53/191 (27%), Positives = 81/191 (42%), Gaps = 12/191 (6%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD------DYEIFSSRRTA 232
R PP ++ DV + + + G P+PTI W+KD D + S R
Sbjct: 41 RQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 100
Query: 233 ITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
+ + + + H + DEG C A N G AV++ LE A RQ ++
Sbjct: 101 LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR-NASLEVALLRDDFRQNPTDVV 159
Query: 292 YEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
E L+ G P PTI W+ D + DD+ E I+ + L I + ++SD G
Sbjct: 160 VAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDK-EERISIRGGKLMISNTRKSDAGM 216
Query: 351 YQIQAKNIIGE 361
Y N++GE
Sbjct: 217 YTCVGTNMVGE 227
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P PP KPQ+ +D N++TL W P T G P Y +E ++ S W +T V
Sbjct: 538 PGPPSKPQV----TDVTKNSVTLSWQPGT-PGTLPASAYIIEAFSQSVSNSW-QTVANHV 591
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL P Y F V A+N G S+ S +SD
Sbjct: 592 KTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 627
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 81.8 bits (193), Expect = 1e-14
Identities = 86/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE--IFSSRR 230
+ S+ + PP F+ R D + V F G P P + W K+ + +F ++
Sbjct: 304 MEASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQP 363
Query: 231 TAITTDESTSV---LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYE 287
+ S S L I SD G C A G + KA+L + R P
Sbjct: 364 QQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIIL 423
Query: 288 DGLLYE---INETIFLKTTIVGKPTPTIEWRHDGHPII-TDDRIEISITPKFSVLKIHSA 343
G + ++ T LK G P P I W +G D R I + L+I +
Sbjct: 424 QGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTLQIKNL 480
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-------------PDPPRNVSVTRQVDKSV 390
+ SD G Y A + GE + + ++ VT P PP VT SV
Sbjct: 481 RISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVTKNSV 540
Query: 391 TLDWEPPADDGGCKVGNYIVEYY-RTGWNVWLKAITSRKTNV-TLFDLIEGSEYKFRIKA 448
TL W+P G YI+E + ++ N W KT + T+ L + Y F ++A
Sbjct: 541 TLSWQP-GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRA 599
Query: 449 ESPYGMSAPSSESSPVR 465
+P G+S PS S PVR
Sbjct: 600 INPQGLSDPSPMSDPVR 616
Score = 70.1 bits (164), Expect = 4e-11
Identities = 59/220 (26%), Positives = 95/220 (43%), Gaps = 19/220 (8%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++R + LE + VEF G P PT+ W KDD ++ R D+ T L
Sbjct: 225 ERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDADLPRGRYD--IKDDYT--L 280
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + +DEG C A NR G A L + A P ++ + D ++ + T+
Sbjct: 281 RIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPP--QFVVRPRDQIVAQ-GRTVTFPC 337
Query: 303 TIVGKPTPTIEWRHDG--------HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
G P P + W+ +G P + R +S T ++ I +RSD G Y Q
Sbjct: 338 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNI---QRSDAGYYICQ 394
Query: 355 AKNIIGEDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLD 393
A + G A + VT D P + + ++++ +D
Sbjct: 395 ALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 434
Score = 60.9 bits (141), Expect = 2e-08
Identities = 56/197 (28%), Positives = 84/197 (42%), Gaps = 14/197 (7%)
Query: 175 VSSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD------DYEIF 226
V R QE PP ++ DV + + + G P+PTI W+KD D +
Sbjct: 21 VDGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDP 80
Query: 227 SSRRTAITTDESTSVLLFH-QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
S R + + + + H + DEG C A N G AV++ LE A RQ
Sbjct: 81 RSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSR-NASLEVALLRDDFRQ 139
Query: 286 YEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAK 344
++ E L+ G P PTI W+ D + DD+ E I+ + L I + +
Sbjct: 140 NPTDVVVAAGEPAILECQPPRGHPEPTIYWKKD--KVRIDDK-EERISIRGGKLMISNTR 196
Query: 345 RSDRGEYQIQAKNIIGE 361
+SD G Y N++GE
Sbjct: 197 KSDAGMYTCVGTNMVGE 213
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P PP KPQ+ +D N++TL W P T G P Y +E ++ S W +T V
Sbjct: 524 PGPPSKPQV----TDVTKNSVTLSWQPGT-PGTLPASAYIIEAFSQSVSNSW-QTVANHV 577
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL P Y F V A+N G S+ S +SD
Sbjct: 578 KTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 613
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/281 (25%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR--GYQVECNRLGSTEWIRT-APPIV 135
PP +P + P++ +++ L W+P H G P+ GY VE +LG+ WIR V
Sbjct: 511 PPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHEAEWV 569
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
PEL + + +QFRV+ALN G S Y E + ++ A + P L+ V
Sbjct: 570 ATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQ 623
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG-E 254
A+E +V F V + + WF D + +S I D + L ++ S G +
Sbjct: 624 AVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQ 681
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKL---RYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+K A + R+ + AAP L + P +L ++E L +
Sbjct: 682 LKFVANG----IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAEL-SDQAAA 736
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ W DG + + E+ + VL + R D G Y+
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 6129
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 6190 SARASAELRIQSP 6202
Score = 74.1 bits (174), Expect = 2e-12
Identities = 71/307 (23%), Positives = 126/307 (41%), Gaps = 19/307 (6%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EP V F KRL+D+ E + F PS AWFK++ +++S + I +E T
Sbjct: 329 REPAVPFKKRLQDLEVREKESATFLCEVPQ-PSTEAAWFKEETRLWASAKYGI-EEEGTE 386
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + + +D+ + T G V A L ++ + PR+ + +T
Sbjct: 387 RRLTVRNVSADDDAVYICETPEGSRTV--AELAVQGNLLRKLPRK----TAVRVGDTAMF 440
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ P + W + ++ R+ IS L I D G+ A +
Sbjct: 441 CVEL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDC-- 497
Query: 361 EDTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTLDWEPPA-DDGGCKVGNYIVEYYRTGW 417
+ + F V+ P PP + V +++ SV L W PP + + Y+VE + G
Sbjct: 498 QTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGT 557
Query: 418 NVWLKAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI-PGRAIDM 473
W++ + +T+ D+ E ++FR+ A + +G S V + P A+
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRT 617
Query: 474 DFLAVEA 480
AV+A
Sbjct: 618 PLKAVQA 624
Score = 73.3 bits (172), Expect = 4e-12
Identities = 71/285 (24%), Positives = 109/285 (38%), Gaps = 17/285 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES--TSVLLFH 245
++ LE+V ALE + F S W DD + +S + E+ +LL
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLK 4402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ P D C T G VT A L + +L ++ + + F T
Sbjct: 4403 NLRPQDS----CRVTFLAGDMVTSAFLTVRGW-RLEILEPLKNAAVRAGAQACFTCTLSE 4457
Query: 306 GKPTPTIEWRHDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P W +G + DD ++ L + SA+ GE ++ + A
Sbjct: 4458 AVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAV----A 4513
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TG-WNVWL 421
+ +TV PDPP + V + +VTL W P DGG + Y VE TG W +
Sbjct: 4514 SARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCH 4573
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + V L G Y+FR+ A P G P VR+
Sbjct: 4574 ELVPGPECVVD--GLAPGETYRFRVAAVGPVGAGEPVHLPQTVRL 4616
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 8/183 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP +++ S + +TL WA DGG L GY+VE + +W R +
Sbjct: 4521 GLPDPPEDAEVVARSS----HTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHEL 4575
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V PE V+ GL P Y+FRVAA+ VG L + ++ P V
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQV 4635
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
A E+ +E V + + W K I R + + +L+ D+GE
Sbjct: 4636 AAGEDVSLELEVV---AEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGE 4692
Query: 255 IKC 257
C
Sbjct: 4693 YHC 4695
Score = 63.3 bits (147), Expect = 5e-09
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 14/171 (8%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P+P ++W KD + + R + D L + D G+ C A N G A
Sbjct: 35 GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAA 94
Query: 270 ARL-------CLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI 321
L C E AP L P + E +E F + + G P P + W DG +
Sbjct: 95 VGLQVDAEAACAEQAPHFLLRPTSIR---VREGSEATF-RCRVGGSPRPAVSWSKDGRRL 150
Query: 322 ITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
D R+ + + S L+I +A+ D G Y+++A+N +G +AA + V
Sbjct: 151 GEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 53.2 bits (122), Expect = 5e-06
Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 13/226 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H R AL D G + Y E D ++ R +++P VF + L D T E + +
Sbjct: 3061 HVLTLRQLALKDSG-TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCET 3119
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
S P + W KD + S R ++ + + LL D G KC A G A +
Sbjct: 3120 STCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACS 3174
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + + A P +R+ +D + E L+ + P ++W + + + D+
Sbjct: 3175 SSIVRVHARP-VRFQEALKDLEVLE-GGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS 3231
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ L + + + D G Y G+ T + +TVTA P
Sbjct: 3232 LRQEGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S PVF+ L++ + V F +G P P++ WFKD + I D+
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ ++P+D G +C A N G + TKA L
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISI--TPKFSVLKIHSAKRSDRGEYQIQAKN 357
L + G+P P W+ DG ++T+ R + + VLKI K+SDRG Y A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQ-LVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASN 315
Query: 358 IIGEDTAAFLVTVTAPPDP 376
++G+ ++ LV V P P
Sbjct: 316 LVGQTYSSVLVVVREPAVP 334
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S P V + LE T E V F P + W+KDD + S + ++ + +
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMSLEGQMA 2523
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L +++P+D G +C A G A + + +EA ++ +D E F
Sbjct: 2524 ELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAR-EVTVTGPLQDAEATEEGWASF- 2577
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+ + +EW +G P+ D EIS + L + S +R+D G
Sbjct: 2578 -SCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG 2625
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q ++ GE C A GG ++ E
Sbjct: 1657 VTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAE 1713
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P++ + L+ + +E I L T+ T+ W DG I R E +
Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773
Query: 336 SVLKIHSAKRSDRGEY 351
L +H A+ D Y
Sbjct: 1774 HTLTVHGAQVLDSAIY 1789
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG V+ E
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA---GGQRVSFHLHITE 1161
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + + E T L V +P + W DG + + ++ + +
Sbjct: 1162 PKGVFAKEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCT 1220
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + ++D GEY +A G +F + +T P
Sbjct: 1221 RRLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEP 1254
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINETI 298
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + T
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEVT- 6222
Query: 299 FLKTTIVGKPTPTIE 313
+ T V K T IE
Sbjct: 6223 -EQETKVPKKTVIIE 6236
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L IVG PTP + W D P+ R ++ L I D G+Y +A+N I
Sbjct: 29 LSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAI 88
Query: 360 GEDTAAFLVTVTA 372
GE AA + V A
Sbjct: 89 GEAFAAVGLQVDA 101
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 4/144 (2%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W+KD ++ SS + + T L+ Q+ +D GE C A GG V+
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA---GGQRVSFQL 1249
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
E + + + E + L + T + W DG + + ++ I
Sbjct: 1250 HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEA 1308
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 1309 AGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 16/156 (10%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
T S+ Q P V ++ L D+ ++ +F + G P+P + WFKD + +S
Sbjct: 5250 TESTTDEGQLPQV-VEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIR 5308
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL------EAAP------KL 280
+T + L + D G+ +N G A + ARL + E P +L
Sbjct: 5309 MTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQL 5368
Query: 281 RYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEW 314
PR E ++ + +I + G+P PT+ W
Sbjct: 5369 VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Score = 43.2 bits (97), Expect = 0.005
Identities = 53/210 (25%), Positives = 77/210 (36%), Gaps = 18/210 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P FI+ L + A E D S + + W K + R ++ D S L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D GE C G T A L + A P R ED E E T L+
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ K P +EWR + DR + L+IH +D GEY + G+
Sbjct: 3823 CEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VCGQ 3876
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVT 391
+ + +TV AP R + Q ++ T
Sbjct: 3877 ERTSATLTVRAPQPVFREPLQSLQAEEGST 3906
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 14/190 (7%)
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT-IAWF 219
V S S LTVS R + F+ L V A E + F S PS + WF
Sbjct: 1879 VCESRDDHTSAQLTVSVPRVVK----FMSGLSTVVAEEGGEATFQCVVS--PSDVAVVWF 1932
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
+D + S + AI+ ++ L ++ D G+I A A + A L + AP
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRVREAPV 1988
Query: 280 LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
L + ++ E + E ++ L+ + +P P + W + + +EI L
Sbjct: 1989 L-FKKKLEPQTVEE-RSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045
Query: 340 IHSAKRSDRG 349
+H+ +DRG
Sbjct: 2046 LHNVGFADRG 2055
Score = 41.9 bits (94), Expect = 0.012
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PVF + L+ + A E S P+ T+ W K ++ ++ R T+ L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ D GE CT G T A L + AAP +R+ R+ + + E T L +
Sbjct: 3949 QDLQREDTGEYTCTC----GSQATSATLTVTAAP-VRFLRELQHQEVDE-GGTAHLCCEL 4002
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+ ++EWR + + ++ + L + ++ D G+Y
Sbjct: 4003 -SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/73 (27%), Positives = 32/73 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P P + W DG P+ I ++ L+I S R D G+Y N +G
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343
Query: 364 AAFLVTVTAPPDP 376
++ + V P +P
Sbjct: 5344 SSARLLVRGPDEP 5356
Score = 39.5 bits (88), Expect = 0.063
Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 8/169 (4%)
Query: 189 KRLEDVTALENDKVEFHVTFSG-IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
KRL+ + LE + F S S W + SS R T +L+ +
Sbjct: 2740 KRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREA 2799
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
PSD GE+ + RG +KA L + P + ED + E + L+ +
Sbjct: 2800 APSDAGEVVFSV--RG--LTSKASLIVRERPAAII-KPLEDQWVAP-GEDVELRCELSRA 2853
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
TP + W D I + ++ ++L I A D GEY + +
Sbjct: 2854 GTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 39.5 bits (88), Expect = 0.063
Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDE 237
PP ++R + + F V G P PT+ W +++ E ++ T + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
L+ + +G C A+N G A+ A L + PK+ + ++ L+
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 6/139 (4%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
++ A PP R VT ++ ++ +VT G P P W KD + RR + D
Sbjct: 232 AEGAPASPPSTGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 237 -ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ VL SD G CTA+N G + L + P + + ++ +D + E
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREPAVPFKKRLQDLEVREKE 348
Query: 296 ETIFLKTTIVGKPTPTIEW 314
FL V +P+ W
Sbjct: 349 SATFL--CEVPQPSTEAAW 365
Score = 38.3 bits (85), Expect = 0.15
Identities = 43/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ L+
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA---GGQRLS---FSLD 1434
Query: 276 AA-PKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISI 331
A PK+ + + E + E+ TT+ V + + W DG + ++ +
Sbjct: 1435 VAEPKVVFAK--EQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEA 1492
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQV 386
L + A ++ GEY +A G +F + V P + P + V +
Sbjct: 1493 VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548
Query: 387 DKSVTLDWE 395
S TL E
Sbjct: 1549 GTSATLSCE 1557
Score = 38.3 bits (85), Expect = 0.15
Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 16/211 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIFSSRRTAITTDESTSVLL 243
P F RL+ + D S S + W K+ E+ + + + + +T LL
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
HQ+ D GE C GG T A L + P++ R D + +E +
Sbjct: 4128 IHQLEAKDTGEYACVT---GGQK-TAASLRV-TEPEVTIVRGLVDAEV-TADEDVEFSCE 4181
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ ++W G P+ +++ E+++ + L++ D G +G
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH----LGNH 4237
Query: 363 TAAFLVTVTAPP----DPPRNVSVTRQVDKS 389
++ +TV AP +P ++V ++ D S
Sbjct: 4238 ASSAQLTVRAPEVTILEPLQDVQLSEGQDAS 4268
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 173 LTVSSDRA-SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
L V ++ A +++ P F+ R + E + F G P P ++W KD +
Sbjct: 97 LQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGP 156
Query: 232 AITTDE--STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 276
+ +E S L P D G + A N G A A L +++
Sbjct: 157 RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 37.9 bits (84), Expect = 0.19
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P F + L+DV E +KV S P+ + W KD E+ + + AI + L
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKAR 271
++ +D+G C A + A K +
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 37.9 bits (84), Expect = 0.19
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+P VF+K L+D++A E + S P + W KD ++ S + T L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 243 LFHQILPSDEGEIKC 257
+ H + P D G C
Sbjct: 2704 VVHDVSPEDAGLYTC 2718
Score = 37.5 bits (83), Expect = 0.26
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 12/160 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + L+ Q +D G+ C A RG + +
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA--RGQRVSFRLHI--- 1067
Query: 276 AAPKLRYPRQYE--DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
PK+ + ++ + + E + L + T + W DG + + ++ + +
Sbjct: 1068 TEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTE-VTWYKDGKKLSSSSKVGMEVKG 1126
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + A ++D GEY +A G +F + +T P
Sbjct: 1127 CTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEP 1162
Score = 36.7 bits (81), Expect = 0.45
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 24/239 (10%)
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ W K ++F + + D + + LL + D G+ C GH + A L +
Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT----GHTQSMASLSV 4063
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITP 333
P+ ++ + + L E + L + + ++W +G + + E+
Sbjct: 4064 R-VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQG 4121
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR-QVDKSVTL 392
L IH + D GEY G+ TAA L VT P V++ R VD VT
Sbjct: 4122 ATRELLIHQLEAKDTGEYACVTG---GQKTAASL-RVTEP-----EVTIVRGLVDAEVTA 4172
Query: 393 DWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESP 451
D + + C+V TG L+ + + VT + +G + R+K +P
Sbjct: 4173 DEDV---EFSCEVS----RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTP 4224
Score = 36.3 bits (80), Expect = 0.59
Identities = 41/170 (24%), Positives = 63/170 (37%), Gaps = 10/170 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQ 246
I+ LEDV E F S + WF D + ++ I VL Q
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE-TIFLKTTIV 305
+ D G I A G A L + P + + R+ D + E + T+ +T+
Sbjct: 3068 LALKDSGTIYFEA----GDQRASAALRVTEKPSV-FSRELTDATITEGEDLTLVCETSTC 3122
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
P + W DG + R ++S + L I A D G Y+ +A
Sbjct: 3123 DIP---VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 35.5 bits (78), Expect = 1.0
Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 13/185 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + I L+ Q +D GE C A GG ++ L +
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA---GGQRLS-FHLDVS 1344
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ Q + I + V + + W DG + + ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQVDKSV 390
L + A ++D GEY +A G +F + V P + P + V Q S
Sbjct: 1405 RRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGAST 1460
Query: 391 TLDWE 395
TL E
Sbjct: 1461 TLSCE 1465
Score = 34.7 bits (76), Expect = 1.8
Identities = 28/141 (19%), Positives = 54/141 (38%), Gaps = 4/141 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ E
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA---GGQRLSFHLDVKE 977
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + E + L + T + W DG + + ++ +
Sbjct: 978 PKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT-EVMWYKDGKKLSSSLKVHVEAKGCR 1036
Query: 336 SVLKIHSAKRSDRGEYQIQAK 356
L + A ++D G+Y +A+
Sbjct: 1037 RRLVVQQAGKTDAGDYSCEAR 1057
Score = 33.9 bits (74), Expect = 3.2
Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ + +D GE C A G L +
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHV- 1619
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISIT 332
A PK+ + + E E+ T+ V + + W DG + + ++ +
Sbjct: 1620 AEPKVVFAK--EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAV 1677
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A +++ GEY +A
Sbjct: 1678 GCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 33.9 bits (74), Expect = 3.2
Identities = 45/211 (21%), Positives = 85/211 (40%), Gaps = 14/211 (6%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIF 226
+ DV T + ++ ++ L+DVT +E F S IPS W +
Sbjct: 2362 DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS-IPSVRPPKWLLGKTVLQ 2420
Query: 227 SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
+ + + + L+ + + G + T G + + ARL + P + R
Sbjct: 2421 AGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTV----GKSRSSARLVVSDIPVV-LTRPL 2475
Query: 287 EDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
E E+ +++ L +P P ++W D P+ ++ ++S+ + + L+I
Sbjct: 2476 EPKTGREL-QSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMP 2532
Query: 346 SDRGEYQIQAKNIIGE---DTAAFLVTVTAP 373
+D G Y+ QA + A VTVT P
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAREVTVTGP 2563
Score = 33.1 bits (72), Expect = 5.5
Identities = 38/184 (20%), Positives = 66/184 (35%), Gaps = 11/184 (5%)
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
R E + E++ + T + + T+ W KD EI S+R + T L H
Sbjct: 1724 RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQV 1783
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D C G + E A K + R E + E+ T+ L +
Sbjct: 1784 LDSAIYSCRVGAEGQDFPVQVE---EVAAK--FCRLLEP-VCGELGGTVTLACEL-SPAC 1836
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ WR + R ++ L + + D GEY +++ +D + +T
Sbjct: 1837 AEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR----DDHTSAQLT 1892
Query: 370 VTAP 373
V+ P
Sbjct: 1893 VSVP 1896
Score = 32.3 bits (70), Expect = 9.6
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 9/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSV-LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ W+KD E+ S + D T L+ + DEG C R G RL +
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 275 EAAPKLRYPRQY--EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ PK+ + ++ L E + L + T + W DG + + ++ + T
Sbjct: 884 -SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVCMEAT 941
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 942 GCTRRLVVQQAGQADAGEYSCEA 964
Score = 32.3 bits (70), Expect = 9.6
Identities = 36/178 (20%), Positives = 69/178 (38%), Gaps = 8/178 (4%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
T +S R ++ ++ L D ++ VEF S + + W + S+ T +
Sbjct: 4148 TAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEV 4207
Query: 234 TT-DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
D L + P D G + + + G HA + A+L + AP++ +D L
Sbjct: 4208 AVRDGRIHTLRLKGVTPEDAGTV---SFHLGNHA-SSAQLTVR-APEVTILEPLQDVQLS 4262
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRG 349
E + F + + W G P+ ++ +I++ +L +H D G
Sbjct: 4263 EGQDASF-QCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG 4319
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/281 (25%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR--GYQVECNRLGSTEWIRT-APPIV 135
PP +P + P++ +++ L W+P H G P+ GY VE +LG+ WIR V
Sbjct: 511 PPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHEAEWV 569
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
PEL + + +QFRV+ALN G S Y E + ++ A + P L+ V
Sbjct: 570 ATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQ 623
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG-E 254
A+E +V F V + + WF D + +S I D + L ++ S G +
Sbjct: 624 AVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQ 681
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKL---RYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+K A + R+ + AAP L + P +L ++E L +
Sbjct: 682 LKFVANG----IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAEL-SDQAAA 736
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ W DG + + E+ + VL + R D G Y+
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 6129
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 6190 SARASAELRIQSP 6202
Score = 74.1 bits (174), Expect = 2e-12
Identities = 71/307 (23%), Positives = 126/307 (41%), Gaps = 19/307 (6%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EP V F KRL+D+ E + F PS AWFK++ +++S + I +E T
Sbjct: 329 REPAVPFKKRLQDLEVREKESATFLCEVPQ-PSTEAAWFKEETRLWASAKYGI-EEEGTE 386
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + + +D+ + T G V A L ++ + PR+ + +T
Sbjct: 387 RRLTVRNVSADDDAVYICETPEGSRTV--AELAVQGNLLRKLPRK----TAVRVGDTAMF 440
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ P + W + ++ R+ IS L I D G+ A +
Sbjct: 441 CVEL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDC-- 497
Query: 361 EDTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTLDWEPPA-DDGGCKVGNYIVEYYRTGW 417
+ + F V+ P PP + V +++ SV L W PP + + Y+VE + G
Sbjct: 498 QTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGT 557
Query: 418 NVWLKAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI-PGRAIDM 473
W++ + +T+ D+ E ++FR+ A + +G S V + P A+
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRT 617
Query: 474 DFLAVEA 480
AV+A
Sbjct: 618 PLKAVQA 624
Score = 73.3 bits (172), Expect = 4e-12
Identities = 71/285 (24%), Positives = 109/285 (38%), Gaps = 17/285 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES--TSVLLFH 245
++ LE+V ALE + F S W DD + +S + E+ +LL
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLK 4402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ P D C T G VT A L + +L ++ + + F T
Sbjct: 4403 NLRPQDS----CRVTFLAGDMVTSAFLTVRGW-RLEILEPLKNAAVRAGAQACFTCTLSE 4457
Query: 306 GKPTPTIEWRHDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P W +G + DD ++ L + SA+ GE ++ + A
Sbjct: 4458 AVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAV----A 4513
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TG-WNVWL 421
+ +TV PDPP + V + +VTL W P DGG + Y VE TG W +
Sbjct: 4514 SARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCH 4573
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + V L G Y+FR+ A P G P VR+
Sbjct: 4574 ELVPGPECVVD--GLAPGETYRFRVAAVGPVGAGEPVHLPQTVRL 4616
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 8/183 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP +++ S + +TL WA DGG L GY+VE + +W R +
Sbjct: 4521 GLPDPPEDAEVVARSS----HTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHEL 4575
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V PE V+ GL P Y+FRVAA+ VG L + ++ P V
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQV 4635
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
A E+ +E V + + W K I R + + +L+ D+GE
Sbjct: 4636 AAGEDVSLELEVV---AEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGE 4692
Query: 255 IKC 257
C
Sbjct: 4693 YHC 4695
Score = 63.3 bits (147), Expect = 5e-09
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 14/171 (8%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P+P ++W KD + + R + D L + D G+ C A N G A
Sbjct: 35 GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAA 94
Query: 270 ARL-------CLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI 321
L C E AP L P + E +E F + + G P P + W DG +
Sbjct: 95 VGLQVDAEAACAEQAPHFLLRPTSIR---VREGSEATF-RCRVGGSPRPAVSWSKDGRRL 150
Query: 322 ITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
D R+ + + S L+I +A+ D G Y+++A+N +G +AA + V
Sbjct: 151 GEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 53.2 bits (122), Expect = 5e-06
Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 13/226 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H R AL D G + Y E D ++ R +++P VF + L D T E + +
Sbjct: 3061 HVLTLRQLALKDSG-TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCET 3119
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
S P + W KD + S R ++ + + LL D G KC A G A +
Sbjct: 3120 STCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACS 3174
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + + A P +R+ +D + E L+ + P ++W + + + D+
Sbjct: 3175 SSIVRVHARP-VRFQEALKDLEVLE-GGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS 3231
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ L + + + D G Y G+ T + +TVTA P
Sbjct: 3232 LRQEGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S PVF+ L++ + V F +G P P++ WFKD + I D+
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ ++P+D G +C A N G + TKA L
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISI--TPKFSVLKIHSAKRSDRGEYQIQAKN 357
L + G+P P W+ DG ++T+ R + + VLKI K+SDRG Y A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQ-LVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASN 315
Query: 358 IIGEDTAAFLVTVTAPPDP 376
++G+ ++ LV V P P
Sbjct: 316 LVGQTYSSVLVVVREPAVP 334
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S P V + LE T E V F P + W+KDD + S + ++ + +
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMSLEGQMA 2523
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L +++P+D G +C A G A + + +EA ++ +D E F
Sbjct: 2524 ELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAR-EVTVTGPLQDAEATEEGWASF- 2577
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+ + +EW +G P+ D EIS + L + S +R+D G
Sbjct: 2578 -SCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG 2625
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q ++ GE C A GG ++ E
Sbjct: 1657 VTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAE 1713
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P++ + L+ + +E I L T+ T+ W DG I R E +
Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773
Query: 336 SVLKIHSAKRSDRGEY 351
L +H A+ D Y
Sbjct: 1774 HTLTVHGAQVLDSAIY 1789
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG V+ E
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA---GGQRVSFHLHITE 1161
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + + E T L V +P + W DG + + ++ + +
Sbjct: 1162 PKGVFAKEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCT 1220
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + ++D GEY +A G +F + +T P
Sbjct: 1221 RRLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEP 1254
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINETI 298
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + T
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEVT- 6222
Query: 299 FLKTTIVGKPTPTIE 313
+ T V K T IE
Sbjct: 6223 -EQETKVPKKTVIIE 6236
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L IVG PTP + W D P+ R ++ L I D G+Y +A+N I
Sbjct: 29 LSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAI 88
Query: 360 GEDTAAFLVTVTA 372
GE AA + V A
Sbjct: 89 GEAFAAVGLQVDA 101
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 4/144 (2%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W+KD ++ SS + + T L+ Q+ +D GE C A GG V+
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA---GGQRVSFQL 1249
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
E + + + E + L + T + W DG + + ++ I
Sbjct: 1250 HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEA 1308
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 1309 AGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 16/156 (10%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
T S+ Q P V ++ L D+ ++ +F + G P+P + WFKD + +S
Sbjct: 5250 TESTTDEGQLPQV-VEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIR 5308
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL------EAAP------KL 280
+T + L + D G+ +N G A + ARL + E P +L
Sbjct: 5309 MTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQL 5368
Query: 281 RYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEW 314
PR E ++ + +I + G+P PT+ W
Sbjct: 5369 VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Score = 43.2 bits (97), Expect = 0.005
Identities = 53/210 (25%), Positives = 77/210 (36%), Gaps = 18/210 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P FI+ L + A E D S + + W K + R ++ D S L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D GE C G T A L + A P R ED E E T L+
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ K P +EWR + DR + L+IH +D GEY + G+
Sbjct: 3823 CEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VCGQ 3876
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVT 391
+ + +TV AP R + Q ++ T
Sbjct: 3877 ERTSATLTVRAPQPVFREPLQSLQAEEGST 3906
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 14/190 (7%)
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT-IAWF 219
V S S LTVS R + F+ L V A E + F S PS + WF
Sbjct: 1879 VCESRDDHTSAQLTVSVPRVVK----FMSGLSTVVAEEGGEATFQCVVS--PSDVAVVWF 1932
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
+D + S + AI+ ++ L ++ D G+I A A + A L + AP
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRVREAPV 1988
Query: 280 LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
L + ++ E + E ++ L+ + +P P + W + + +EI L
Sbjct: 1989 L-FKKKLEPQTVEE-RSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045
Query: 340 IHSAKRSDRG 349
+H+ +DRG
Sbjct: 2046 LHNVGFADRG 2055
Score = 41.9 bits (94), Expect = 0.012
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PVF + L+ + A E S P+ T+ W K ++ ++ R T+ L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ D GE CT G T A L + AAP +R+ R+ + + E T L +
Sbjct: 3949 QDLQREDTGEYTCTC----GSQATSATLTVTAAP-VRFLRELQHQEVDE-GGTAHLCCEL 4002
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+ ++EWR + + ++ + L + ++ D G+Y
Sbjct: 4003 -SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/73 (27%), Positives = 32/73 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P P + W DG P+ I ++ L+I S R D G+Y N +G
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343
Query: 364 AAFLVTVTAPPDP 376
++ + V P +P
Sbjct: 5344 SSARLLVRGPDEP 5356
Score = 39.5 bits (88), Expect = 0.063
Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 8/169 (4%)
Query: 189 KRLEDVTALENDKVEFHVTFSG-IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
KRL+ + LE + F S S W + SS R T +L+ +
Sbjct: 2740 KRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREA 2799
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
PSD GE+ + RG +KA L + P + ED + E + L+ +
Sbjct: 2800 APSDAGEVVFSV--RG--LTSKASLIVRERPAAII-KPLEDQWVAP-GEDVELRCELSRA 2853
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
TP + W D I + ++ ++L I A D GEY + +
Sbjct: 2854 GTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 39.5 bits (88), Expect = 0.063
Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDE 237
PP ++R + + F V G P PT+ W +++ E ++ T + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
L+ + +G C A+N G A+ A L + PK+ + ++ L+
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 6/139 (4%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
++ A PP R VT ++ ++ +VT G P P W KD + RR + D
Sbjct: 232 AEGAPASPPSTGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 237 -ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ VL SD G CTA+N G + L + P + + ++ +D + E
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREPAVPFKKRLQDLEVREKE 348
Query: 296 ETIFLKTTIVGKPTPTIEW 314
FL V +P+ W
Sbjct: 349 SATFL--CEVPQPSTEAAW 365
Score = 38.3 bits (85), Expect = 0.15
Identities = 43/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ L+
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA---GGQRLS---FSLD 1434
Query: 276 AA-PKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISI 331
A PK+ + + E + E+ TT+ V + + W DG + ++ +
Sbjct: 1435 VAEPKVVFAK--EQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEA 1492
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQV 386
L + A ++ GEY +A G +F + V P + P + V +
Sbjct: 1493 VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548
Query: 387 DKSVTLDWE 395
S TL E
Sbjct: 1549 GTSATLSCE 1557
Score = 38.3 bits (85), Expect = 0.15
Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 16/211 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIFSSRRTAITTDESTSVLL 243
P F RL+ + D S S + W K+ E+ + + + + +T LL
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
HQ+ D GE C GG T A L + P++ R D + +E +
Sbjct: 4128 IHQLEAKDTGEYACVT---GGQK-TAASLRV-TEPEVTIVRGLVDAEV-TADEDVEFSCE 4181
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ ++W G P+ +++ E+++ + L++ D G +G
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH----LGNH 4237
Query: 363 TAAFLVTVTAPP----DPPRNVSVTRQVDKS 389
++ +TV AP +P ++V ++ D S
Sbjct: 4238 ASSAQLTVRAPEVTILEPLQDVQLSEGQDAS 4268
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 173 LTVSSDRA-SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
L V ++ A +++ P F+ R + E + F G P P ++W KD +
Sbjct: 97 LQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGP 156
Query: 232 AITTDE--STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 276
+ +E S L P D G + A N G A A L +++
Sbjct: 157 RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 37.9 bits (84), Expect = 0.19
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P F + L+DV E +KV S P+ + W KD E+ + + AI + L
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKAR 271
++ +D+G C A + A K +
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 37.9 bits (84), Expect = 0.19
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+P VF+K L+D++A E + S P + W KD ++ S + T L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 243 LFHQILPSDEGEIKC 257
+ H + P D G C
Sbjct: 2704 VVHDVSPEDAGLYTC 2718
Score = 37.5 bits (83), Expect = 0.26
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 12/160 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + L+ Q +D G+ C A RG + +
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA--RGQRVSFRLHI--- 1067
Query: 276 AAPKLRYPRQYE--DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
PK+ + ++ + + E + L + T + W DG + + ++ + +
Sbjct: 1068 TEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTE-VTWYKDGKKLSSSSKVGMEVKG 1126
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + A ++D GEY +A G +F + +T P
Sbjct: 1127 CTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEP 1162
Score = 36.7 bits (81), Expect = 0.45
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 24/239 (10%)
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ W K ++F + + D + + LL + D G+ C GH + A L +
Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT----GHTQSMASLSV 4063
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITP 333
P+ ++ + + L E + L + + ++W +G + + E+
Sbjct: 4064 R-VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQG 4121
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR-QVDKSVTL 392
L IH + D GEY G+ TAA L VT P V++ R VD VT
Sbjct: 4122 ATRELLIHQLEAKDTGEYACVTG---GQKTAASL-RVTEP-----EVTIVRGLVDAEVTA 4172
Query: 393 DWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESP 451
D + + C+V TG L+ + + VT + +G + R+K +P
Sbjct: 4173 DEDV---EFSCEVS----RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTP 4224
Score = 36.3 bits (80), Expect = 0.59
Identities = 41/170 (24%), Positives = 63/170 (37%), Gaps = 10/170 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQ 246
I+ LEDV E F S + WF D + ++ I VL Q
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE-TIFLKTTIV 305
+ D G I A G A L + P + + R+ D + E + T+ +T+
Sbjct: 3068 LALKDSGTIYFEA----GDQRASAALRVTEKPSV-FSRELTDATITEGEDLTLVCETSTC 3122
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
P + W DG + R ++S + L I A D G Y+ +A
Sbjct: 3123 DIP---VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 35.5 bits (78), Expect = 1.0
Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 13/185 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + I L+ Q +D GE C A GG ++ L +
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA---GGQRLS-FHLDVS 1344
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ Q + I + V + + W DG + + ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQVDKSV 390
L + A ++D GEY +A G +F + V P + P + V Q S
Sbjct: 1405 RRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGAST 1460
Query: 391 TLDWE 395
TL E
Sbjct: 1461 TLSCE 1465
Score = 34.7 bits (76), Expect = 1.8
Identities = 28/141 (19%), Positives = 54/141 (38%), Gaps = 4/141 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ E
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA---GGQRLSFHLDVKE 977
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + E + L + T + W DG + + ++ +
Sbjct: 978 PKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT-EVMWYKDGKKLSSSLKVHVEAKGCR 1036
Query: 336 SVLKIHSAKRSDRGEYQIQAK 356
L + A ++D G+Y +A+
Sbjct: 1037 RRLVVQQAGKTDAGDYSCEAR 1057
Score = 33.9 bits (74), Expect = 3.2
Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ + +D GE C A G L +
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHV- 1619
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISIT 332
A PK+ + + E E+ T+ V + + W DG + + ++ +
Sbjct: 1620 AEPKVVFAK--EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAV 1677
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A +++ GEY +A
Sbjct: 1678 GCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 33.9 bits (74), Expect = 3.2
Identities = 45/211 (21%), Positives = 85/211 (40%), Gaps = 14/211 (6%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIF 226
+ DV T + ++ ++ L+DVT +E F S IPS W +
Sbjct: 2362 DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS-IPSVRPPKWLLGKTVLQ 2420
Query: 227 SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
+ + + + L+ + + G + T G + + ARL + P + R
Sbjct: 2421 AGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTV----GKSRSSARLVVSDIPVV-LTRPL 2475
Query: 287 EDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
E E+ +++ L +P P ++W D P+ ++ ++S+ + + L+I
Sbjct: 2476 EPKTGREL-QSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMP 2532
Query: 346 SDRGEYQIQAKNIIGE---DTAAFLVTVTAP 373
+D G Y+ QA + A VTVT P
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAREVTVTGP 2563
Score = 33.1 bits (72), Expect = 5.5
Identities = 38/184 (20%), Positives = 66/184 (35%), Gaps = 11/184 (5%)
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
R E + E++ + T + + T+ W KD EI S+R + T L H
Sbjct: 1724 RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQV 1783
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D C G + E A K + R E + E+ T+ L +
Sbjct: 1784 LDSAIYSCRVGAEGQDFPVQVE---EVAAK--FCRLLEP-VCGELGGTVTLACEL-SPAC 1836
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ WR + R ++ L + + D GEY +++ +D + +T
Sbjct: 1837 AEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR----DDHTSAQLT 1892
Query: 370 VTAP 373
V+ P
Sbjct: 1893 VSVP 1896
Score = 32.3 bits (70), Expect = 9.6
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 9/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSV-LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ W+KD E+ S + D T L+ + DEG C R G RL +
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 275 EAAPKLRYPRQY--EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ PK+ + ++ L E + L + T + W DG + + ++ + T
Sbjct: 884 -SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVCMEAT 941
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 942 GCTRRLVVQQAGQADAGEYSCEA 964
Score = 32.3 bits (70), Expect = 9.6
Identities = 36/178 (20%), Positives = 69/178 (38%), Gaps = 8/178 (4%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
T +S R ++ ++ L D ++ VEF S + + W + S+ T +
Sbjct: 4148 TAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEV 4207
Query: 234 TT-DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
D L + P D G + + + G HA + A+L + AP++ +D L
Sbjct: 4208 AVRDGRIHTLRLKGVTPEDAGTV---SFHLGNHA-SSAQLTVR-APEVTILEPLQDVQLS 4262
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRG 349
E + F + + W G P+ ++ +I++ +L +H D G
Sbjct: 4263 EGQDASF-QCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG 4319
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/281 (25%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR--GYQVECNRLGSTEWIRT-APPIV 135
PP +P + P++ +++ L W+P H G P+ GY VE +LG+ WIR V
Sbjct: 511 PPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHEAEWV 569
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
PEL + + +QFRV+ALN G S Y E + ++ A + P L+ V
Sbjct: 570 ATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQ 623
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG-E 254
A+E +V F V + + WF D + +S I D + L ++ S G +
Sbjct: 624 AVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQ 681
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKL---RYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+K A + R+ + AAP L + P +L ++E L +
Sbjct: 682 LKFVANG----IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAEL-SDQAAA 736
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ W DG + + E+ + VL + R D G Y+
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 6129
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 6190 SARASAELRIQSP 6202
Score = 74.1 bits (174), Expect = 2e-12
Identities = 71/307 (23%), Positives = 126/307 (41%), Gaps = 19/307 (6%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EP V F KRL+D+ E + F PS AWFK++ +++S + I +E T
Sbjct: 329 REPAVPFKKRLQDLEVREKESATFLCEVPQ-PSTEAAWFKEETRLWASAKYGI-EEEGTE 386
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + + +D+ + T G V A L ++ + PR+ + +T
Sbjct: 387 RRLTVRNVSADDDAVYICETPEGSRTV--AELAVQGNLLRKLPRK----TAVRVGDTAMF 440
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ P + W + ++ R+ IS L I D G+ A +
Sbjct: 441 CVEL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDC-- 497
Query: 361 EDTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTLDWEPPA-DDGGCKVGNYIVEYYRTGW 417
+ + F V+ P PP + V +++ SV L W PP + + Y+VE + G
Sbjct: 498 QTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGT 557
Query: 418 NVWLKAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI-PGRAIDM 473
W++ + +T+ D+ E ++FR+ A + +G S V + P A+
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRT 617
Query: 474 DFLAVEA 480
AV+A
Sbjct: 618 PLKAVQA 624
Score = 73.3 bits (172), Expect = 4e-12
Identities = 71/285 (24%), Positives = 109/285 (38%), Gaps = 17/285 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES--TSVLLFH 245
++ LE+V ALE + F S W DD + +S + E+ +LL
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLK 4402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ P D C T G VT A L + +L ++ + + F T
Sbjct: 4403 NLRPQDS----CRVTFLAGDMVTSAFLTVRGW-RLEILEPLKNAAVRAGAQACFTCTLSE 4457
Query: 306 GKPTPTIEWRHDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P W +G + DD ++ L + SA+ GE ++ + A
Sbjct: 4458 AVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAV----A 4513
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TG-WNVWL 421
+ +TV PDPP + V + +VTL W P DGG + Y VE TG W +
Sbjct: 4514 SARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCH 4573
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + V L G Y+FR+ A P G P VR+
Sbjct: 4574 ELVPGPECVVD--GLAPGETYRFRVAAVGPVGAGEPVHLPQTVRL 4616
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 8/183 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP +++ S + +TL WA DGG L GY+VE + +W R +
Sbjct: 4521 GLPDPPEDAEVVARSS----HTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHEL 4575
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V PE V+ GL P Y+FRVAA+ VG L + ++ P V
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQV 4635
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
A E+ +E V + + W K I R + + +L+ D+GE
Sbjct: 4636 AAGEDVSLELEVV---AEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGE 4692
Query: 255 IKC 257
C
Sbjct: 4693 YHC 4695
Score = 63.3 bits (147), Expect = 5e-09
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 14/171 (8%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P+P ++W KD + + R + D L + D G+ C A N G A
Sbjct: 35 GNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAA 94
Query: 270 ARL-------CLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI 321
L C E AP L P + E +E F + + G P P + W DG +
Sbjct: 95 VGLQVDAEAACAEQAPHFLLRPTSIR---VREGSEATF-RCRVGGSPRPAVSWSKDGRRL 150
Query: 322 ITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
D R+ + + S L+I +A+ D G Y+++A+N +G +AA + V
Sbjct: 151 GEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 53.2 bits (122), Expect = 5e-06
Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 13/226 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H R AL D G + Y E D ++ R +++P VF + L D T E + +
Sbjct: 3061 HVLTLRQLALKDSG-TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCET 3119
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
S P + W KD + S R ++ + + LL D G KC A G A +
Sbjct: 3120 STCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACS 3174
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + + A P +R+ +D + E L+ + P ++W + + + D+
Sbjct: 3175 SSIVRVHARP-VRFQEALKDLEVLE-GGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS 3231
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ L + + + D G Y G+ T + +TVTA P
Sbjct: 3232 LRQEGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S PVF+ L++ + V F +G P P++ WFKD + I D+
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ ++P+D G +C A N G + TKA L
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISI--TPKFSVLKIHSAKRSDRGEYQIQAKN 357
L + G+P P W+ DG ++T+ R + + VLKI K+SDRG Y A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQ-LVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASN 315
Query: 358 IIGEDTAAFLVTVTAPPDP 376
++G+ ++ LV V P P
Sbjct: 316 LVGQTYSSVLVVVREPAVP 334
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S P V + LE T E V F P + W+KDD + S + ++ + +
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMSLEGQMA 2523
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L +++P+D G +C A G A + + +EA ++ +D E F
Sbjct: 2524 ELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAR-EVTVTGPLQDAEATEEGWASF- 2577
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+ + +EW +G P+ D EIS + L + S +R+D G
Sbjct: 2578 -SCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG 2625
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q ++ GE C A GG ++ E
Sbjct: 1657 VTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQAEAGEYSCEA---GGQQLSFRLQVAE 1713
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P++ + L+ + +E I L T+ T+ W DG I R E +
Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773
Query: 336 SVLKIHSAKRSDRGEY 351
L +H A+ D Y
Sbjct: 1774 HTLTVHGAQVLDSAIY 1789
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG V+ E
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA---GGQRVSFHLHITE 1161
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + + E T L V +P + W DG + + ++ + +
Sbjct: 1162 PKGVFAKEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCT 1220
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + ++D GEY +A G +F + +T P
Sbjct: 1221 RRLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEP 1254
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 6105 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINETI 298
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + T
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEVT- 6222
Query: 299 FLKTTIVGKPTPTIE 313
+ T V K T IE
Sbjct: 6223 -EQETKVPKKTVIIE 6236
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L IVG PTP + W D P+ R ++ L I D G+Y +A+N I
Sbjct: 29 LSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAI 88
Query: 360 GEDTAAFLVTVTA 372
GE AA + V A
Sbjct: 89 GEAFAAVGLQVDA 101
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 4/144 (2%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W+KD ++ SS + + T L+ Q+ +D GE C A GG V+
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA---GGQRVSFQL 1249
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
E + + + E + L + T + W DG + + ++ I
Sbjct: 1250 HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEA 1308
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 1309 AGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 16/156 (10%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
T S+ Q P V ++ L D+ ++ +F + G P+P + WFKD + +S
Sbjct: 5250 TESTTDEGQLPQV-VEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIR 5308
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL------EAAP------KL 280
+T + L + D G+ +N G A + ARL + E P +L
Sbjct: 5309 MTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQL 5368
Query: 281 RYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEW 314
PR E ++ + +I + G+P PT+ W
Sbjct: 5369 VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Score = 43.2 bits (97), Expect = 0.005
Identities = 53/210 (25%), Positives = 77/210 (36%), Gaps = 18/210 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P FI+ L + A E D S + + W K + R ++ D S L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D GE C G T A L + A P R ED E E T L+
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ K P +EWR + DR + L+IH +D GEY + G+
Sbjct: 3823 CEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VCGQ 3876
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVT 391
+ + +TV AP R + Q ++ T
Sbjct: 3877 ERTSATLTVRAPQPVFREPLQSLQAEEGST 3906
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 14/190 (7%)
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT-IAWF 219
V S S LTVS R + F+ L V A E + F S PS + WF
Sbjct: 1879 VCESRDDHTSAQLTVSVPRVVK----FMSGLSTVVAEEGGEATFQCVVS--PSDVAVVWF 1932
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
+D + S + AI+ ++ L ++ D G+I A A + A L + AP
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRVREAPV 1988
Query: 280 LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
L + ++ E + E ++ L+ + +P P + W + + +EI L
Sbjct: 1989 L-FKKKLEPQTVEE-RSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045
Query: 340 IHSAKRSDRG 349
+H+ +DRG
Sbjct: 2046 LHNVGFADRG 2055
Score = 41.9 bits (94), Expect = 0.012
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PVF + L+ + A E S P+ T+ W K ++ ++ R T+ L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ D GE CT G T A L + AAP +R+ R+ + + E T L +
Sbjct: 3949 QDLQREDTGEYTCTC----GSQATSATLTVTAAP-VRFLRELQHQEVDE-GGTAHLCCEL 4002
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+ ++EWR + + ++ + L + ++ D G+Y
Sbjct: 4003 -SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/73 (27%), Positives = 32/73 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P P + W DG P+ I ++ L+I S R D G+Y N +G
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343
Query: 364 AAFLVTVTAPPDP 376
++ + V P +P
Sbjct: 5344 SSARLLVRGPDEP 5356
Score = 39.5 bits (88), Expect = 0.063
Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 8/169 (4%)
Query: 189 KRLEDVTALENDKVEFHVTFSG-IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
KRL+ + LE + F S S W + SS R T +L+ +
Sbjct: 2740 KRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREA 2799
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
PSD GE+ + RG +KA L + P + ED + E + L+ +
Sbjct: 2800 APSDAGEVVFSV--RG--LTSKASLIVRERPAAII-KPLEDQWVAP-GEDVELRCELSRA 2853
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
TP + W D I + ++ ++L I A D GEY + +
Sbjct: 2854 GTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 39.5 bits (88), Expect = 0.063
Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDE 237
PP ++R + + F V G P PT+ W +++ E ++ T + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
L+ + +G C A+N G A+ A L + PK+ + ++ L+
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 6/139 (4%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
++ A PP R VT ++ ++ +VT G P P W KD + RR + D
Sbjct: 232 AEGAPASPPSTGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 237 -ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ VL SD G CTA+N G + L + P + + ++ +D + E
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREPAVPFKKRLQDLEVREKE 348
Query: 296 ETIFLKTTIVGKPTPTIEW 314
FL V +P+ W
Sbjct: 349 SATFL--CEVPQPSTEAAW 365
Score = 38.3 bits (85), Expect = 0.15
Identities = 43/189 (22%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ L+
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA---GGQRLS---FSLD 1434
Query: 276 AA-PKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISI 331
A PK+ + + E + E+ TT+ V + + W DG + ++ +
Sbjct: 1435 VAEPKVVFAK--EQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEA 1492
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQV 386
L + A ++ GEY +A G +F + V P + P + V +
Sbjct: 1493 VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548
Query: 387 DKSVTLDWE 395
S TL E
Sbjct: 1549 GTSATLSCE 1557
Score = 38.3 bits (85), Expect = 0.15
Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 16/211 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIFSSRRTAITTDESTSVLL 243
P F RL+ + D S S + W K+ E+ + + + + +T LL
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
HQ+ D GE C GG T A L + P++ R D + +E +
Sbjct: 4128 IHQLEAKDTGEYACVT---GGQK-TAASLRV-TEPEVTIVRGLVDAEV-TADEDVEFSCE 4181
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ ++W G P+ +++ E+++ + L++ D G +G
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH----LGNH 4237
Query: 363 TAAFLVTVTAPP----DPPRNVSVTRQVDKS 389
++ +TV AP +P ++V ++ D S
Sbjct: 4238 ASSAQLTVRAPEVTILEPLQDVQLSEGQDAS 4268
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 173 LTVSSDRA-SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
L V ++ A +++ P F+ R + E + F G P P ++W KD +
Sbjct: 97 LQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGP 156
Query: 232 AITTDE--STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 276
+ +E S L P D G + A N G A A L +++
Sbjct: 157 RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 37.9 bits (84), Expect = 0.19
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P F + L+DV E +KV S P+ + W KD E+ + + AI + L
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKAR 271
++ +D+G C A + A K +
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 37.9 bits (84), Expect = 0.19
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+P VF+K L+D++A E + S P + W KD ++ S + T L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 243 LFHQILPSDEGEIKC 257
+ H + P D G C
Sbjct: 2704 VVHDVSPEDAGLYTC 2718
Score = 37.5 bits (83), Expect = 0.26
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 12/160 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + L+ Q +D G+ C A RG + +
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA--RGQRVSFRLHI--- 1067
Query: 276 AAPKLRYPRQYE--DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
PK+ + ++ + + E + L + T + W DG + + ++ + +
Sbjct: 1068 TEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTE-VTWYKDGKKLSSSSKVGMEVKG 1126
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + A ++D GEY +A G +F + +T P
Sbjct: 1127 CTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEP 1162
Score = 36.7 bits (81), Expect = 0.45
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 24/239 (10%)
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ W K ++F + + D + + LL + D G+ C GH + A L +
Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT----GHTQSMASLSV 4063
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITP 333
P+ ++ + + L E + L + + ++W +G + + E+
Sbjct: 4064 R-VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQG 4121
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR-QVDKSVTL 392
L IH + D GEY G+ TAA L VT P V++ R VD VT
Sbjct: 4122 ATRELLIHQLEAKDTGEYACVTG---GQKTAASL-RVTEP-----EVTIVRGLVDAEVTA 4172
Query: 393 DWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESP 451
D + + C+V TG L+ + + VT + +G + R+K +P
Sbjct: 4173 DEDV---EFSCEVS----RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTP 4224
Score = 36.3 bits (80), Expect = 0.59
Identities = 41/170 (24%), Positives = 63/170 (37%), Gaps = 10/170 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQ 246
I+ LEDV E F S + WF D + ++ I VL Q
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE-TIFLKTTIV 305
+ D G I A G A L + P + + R+ D + E + T+ +T+
Sbjct: 3068 LALKDSGTIYFEA----GDQRASAALRVTEKPSV-FSRELTDATITEGEDLTLVCETSTC 3122
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
P + W DG + R ++S + L I A D G Y+ +A
Sbjct: 3123 DIP---VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 35.5 bits (78), Expect = 1.0
Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 13/185 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + I L+ Q +D GE C A GG ++ L +
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA---GGQRLS-FHLDVS 1344
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ Q + I + V + + W DG + + ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQVDKSV 390
L + A ++D GEY +A G +F + V P + P + V Q S
Sbjct: 1405 RRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGAST 1460
Query: 391 TLDWE 395
TL E
Sbjct: 1461 TLSCE 1465
Score = 34.7 bits (76), Expect = 1.8
Identities = 28/141 (19%), Positives = 54/141 (38%), Gaps = 4/141 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ E
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEA---GGQRLSFHLDVKE 977
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + E + L + T + W DG + + ++ +
Sbjct: 978 PKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT-EVMWYKDGKKLSSSLKVHVEAKGCR 1036
Query: 336 SVLKIHSAKRSDRGEYQIQAK 356
L + A ++D G+Y +A+
Sbjct: 1037 RRLVVQQAGKTDAGDYSCEAR 1057
Score = 33.9 bits (74), Expect = 3.2
Identities = 30/143 (20%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ + +D GE C A G L +
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHV- 1619
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISIT 332
A PK+ + + E E+ T+ V + + W DG + + ++ +
Sbjct: 1620 AEPKVVFAK--EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAV 1677
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A +++ GEY +A
Sbjct: 1678 GCTRRLVVQQAGQAEAGEYSCEA 1700
Score = 33.9 bits (74), Expect = 3.2
Identities = 45/211 (21%), Positives = 85/211 (40%), Gaps = 14/211 (6%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIF 226
+ DV T + ++ ++ L+DVT +E F S IPS W +
Sbjct: 2362 DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS-IPSVRPPKWLLGKTVLQ 2420
Query: 227 SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
+ + + + L+ + + G + T G + + ARL + P + R
Sbjct: 2421 AGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTV----GKSRSSARLVVSDIPVV-LTRPL 2475
Query: 287 EDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
E E+ +++ L +P P ++W D P+ ++ ++S+ + + L+I
Sbjct: 2476 EPKTGREL-QSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMP 2532
Query: 346 SDRGEYQIQAKNIIGE---DTAAFLVTVTAP 373
+D G Y+ QA + A VTVT P
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAREVTVTGP 2563
Score = 33.1 bits (72), Expect = 5.5
Identities = 38/184 (20%), Positives = 66/184 (35%), Gaps = 11/184 (5%)
Query: 190 RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
R E + E++ + T + + T+ W KD EI S+R + T L H
Sbjct: 1724 RREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQV 1783
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D C G + E A K + R E + E+ T+ L +
Sbjct: 1784 LDSAIYSCRVGAEGQDFPVQVE---EVAAK--FCRLLEP-VCGELGGTVTLACEL-SPAC 1836
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVT 369
+ WR + R ++ L + + D GEY +++ +D + +T
Sbjct: 1837 AEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCESR----DDHTSAQLT 1892
Query: 370 VTAP 373
V+ P
Sbjct: 1893 VSVP 1896
Score = 32.3 bits (70), Expect = 9.6
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 9/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSV-LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ W+KD E+ S + D T L+ + DEG C R G RL +
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 275 EAAPKLRYPRQY--EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ PK+ + ++ L E + L + T + W DG + + ++ + T
Sbjct: 884 -SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVCMEAT 941
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 942 GCTRRLVVQQAGQADAGEYSCEA 964
Score = 32.3 bits (70), Expect = 9.6
Identities = 36/178 (20%), Positives = 69/178 (38%), Gaps = 8/178 (4%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
T +S R ++ ++ L D ++ VEF S + + W + S+ T +
Sbjct: 4148 TAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEV 4207
Query: 234 TT-DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
D L + P D G + + + G HA + A+L + AP++ +D L
Sbjct: 4208 AVRDGRIHTLRLKGVTPEDAGTV---SFHLGNHA-SSAQLTVR-APEVTILEPLQDVQLS 4262
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRG 349
E + F + + W G P+ ++ +I++ +L +H D G
Sbjct: 4263 EGQDASF-QCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG 4319
>AJ314898-1|CAC85746.1| 646|Homo sapiens obscurin protein.
Length = 646
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/281 (25%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR--GYQVECNRLGSTEWIRT-APPIV 135
PP +P + P++ +++ L W+P H G P+ GY VE +LG+ WIR V
Sbjct: 91 PPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHEAEWV 149
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
PEL + + +QFRV+ALN G S Y E + ++ A + P L+ V
Sbjct: 150 ATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQ 203
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG-E 254
A+E +V F V + + WF D + +S I D + L ++ S G +
Sbjct: 204 AVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQ 261
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKL---RYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+K A + R+ + AAP L + P +L ++E L +
Sbjct: 262 LKFVANG----IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAEL-SDQAAA 316
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ W DG + + E+ + VL + R D G Y+
Sbjct: 317 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 357
Score = 52.4 bits (120), Expect = 8e-06
Identities = 41/180 (22%), Positives = 73/180 (40%), Gaps = 9/180 (5%)
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFL 367
P + W + ++ R+ IS L I D G+ A + + + F
Sbjct: 27 PVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDC--QTSTQFC 84
Query: 368 VTVTAPP--DPPRNVSVTRQVDKSVTLDWEPPA-DDGGCKVGNYIVEYYRTGWNVWLKAI 424
V+ P PP + V +++ SV L W PP + + Y+VE + G W++
Sbjct: 85 VSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYTWIRCH 144
Query: 425 TSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI-PGRAIDMDFLAVEA 480
+ +T+ D+ E ++FR+ A + +G S V + P A+ AV+A
Sbjct: 145 EAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQA 204
Score = 36.7 bits (81), Expect = 0.45
Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT-NRGGHAVTKARLCL 274
+ W+KD ++ SS + + L+ Q+ +D GE C A R + + ++
Sbjct: 501 VTWYKDGKKLSSSSKVHVEAVGCMRRLVVQQVGQADSGEYSCEARGQRVSFRLDEPKVVF 560
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
R Q E G + T+ + V + + W DG + + ++ + T
Sbjct: 561 AKEQLARRKLQAEAG----ASATLSCE---VAQAQTEVTWYKDGKKLSSSSKVCMEATGC 613
Query: 335 FSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 614 TRRLVVQQAGQADAGEYSCEA 634
Score = 33.5 bits (73), Expect = 4.2
Identities = 31/145 (21%), Positives = 56/145 (38%), Gaps = 11/145 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSV-LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ W+KD E+ S + D T L+ + DEG C R G RL +
Sbjct: 408 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 463
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISI 331
+ PK + + E E+ + T+ V + + W DG + + ++ +
Sbjct: 464 -SEPKAVFAK--EQPACREVQAEVGASATLSCEVAQDQMEVTWYKDGKKLSSSSKVHVEA 520
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAK 356
L + ++D GEY +A+
Sbjct: 521 VGCMRRLVVQQVGQADSGEYSCEAR 545
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 79.8 bits (188), Expect = 5e-14
Identities = 73/281 (25%), Positives = 119/281 (42%), Gaps = 21/281 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLR--GYQVECNRLGSTEWIRT-APPIV 135
PP +P + P++ +++ L W+P H G P+ GY VE +LG+ WIR V
Sbjct: 511 PPLQPPVDPVVKARMESSVILSWSPPPH-GERPVTIDGYLVEKKKLGTYTWIRCHEAEWV 569
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
PEL + + +QFRV+ALN G S Y E + ++ A + P L+ V
Sbjct: 570 ATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTP------LKAVQ 623
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG-E 254
A+E +V F V + + WF D + +S I D + L ++ S G +
Sbjct: 624 AVEGGEVTFSVDLT--VASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQ 681
Query: 255 IKCTATNRGGHAVTKARLCLEAAPKL---RYPRQYEDGLLYEINETIFLKTTIVGKPTPT 311
+K A + R+ + AAP L + P +L ++E L +
Sbjct: 682 LKFVANG----IESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAEL-SDQAAA 736
Query: 312 IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ W DG + + E+ + VL + R D G Y+
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYE 777
Score = 74.5 bits (175), Expect = 2e-12
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVLASPFVEGEDAQF-TC 6129
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 6130 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 6189
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 6190 SARASAELRIQSP 6202
Score = 74.1 bits (174), Expect = 2e-12
Identities = 71/307 (23%), Positives = 126/307 (41%), Gaps = 19/307 (6%)
Query: 182 QEPPV-FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
+EP V F KRL+D+ E + F PS AWFK++ +++S + I +E T
Sbjct: 329 REPAVPFKKRLQDLEVREKESATFLCEVPQ-PSTEAAWFKEETRLWASAKYGI-EEEGTE 386
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + + +D+ + T G V A L ++ + PR+ + +T
Sbjct: 387 RRLTVRNVSADDDAVYICETPEGSRTV--AELAVQGNLLRKLPRK----TAVRVGDTAMF 440
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ P + W + ++ R+ IS L I D G+ A +
Sbjct: 441 CVEL-AVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDC-- 497
Query: 361 EDTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTLDWEPPA-DDGGCKVGNYIVEYYRTGW 417
+ + F V+ P PP + V +++ SV L W PP + + Y+VE + G
Sbjct: 498 QTSTRFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGT 557
Query: 418 NVWLKAITSR---KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI-PGRAIDM 473
W++ + +T+ D+ E ++FR+ A + +G S V + P A+
Sbjct: 558 YTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRT 617
Query: 474 DFLAVEA 480
AV+A
Sbjct: 618 PLKAVQA 624
Score = 71.7 bits (168), Expect = 1e-11
Identities = 71/285 (24%), Positives = 108/285 (37%), Gaps = 17/285 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES--TSVLLFH 245
++ LE+V ALE + F S W DD + +S + E+ +LL
Sbjct: 4343 VRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVRTSENAEVVFFENGLRHLLLLK 4402
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ P D C T G VT A L + +L ++ + + F T
Sbjct: 4403 NLRPQDS----CRVTFLAGDMVTSAFLTVRGW-RLEILEPLKNAAVRAGAQARFTCTLSE 4457
Query: 306 GKPTPTIEWRHDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P W +G + DD ++ L + SA+ GE ++ + A
Sbjct: 4458 AVPVGEASWYINGAAVQPDDSDWTVTADGSHQALLLRSAQPHHAGEVTFACRDAV----A 4513
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TG-WNVWL 421
+ +TV PDPP + V +VTL W P DGG + Y VE TG W +
Sbjct: 4514 SARLTVLGLPDPPEDAEVVAHSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCH 4573
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ + + V L G Y+FR+ A P G P VR+
Sbjct: 4574 ELVPGPECVVD--GLAPGETYRFRVAAVGPVGAGEPVHLPQTVRL 4616
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 8/183 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP +++ S + +TL WA DGG L GY+VE + +W R +
Sbjct: 4521 GLPDPPEDAEVVAHSS----HTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHEL 4575
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V PE V+ GL P Y+FRVAA+ VG L + ++ P V
Sbjct: 4576 VPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQV 4635
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
A E+ +E V + + W K I R + + +L+ D+GE
Sbjct: 4636 AAGEDVSLELEVV---AEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGE 4692
Query: 255 IKC 257
C
Sbjct: 4693 YHC 4695
Score = 63.3 bits (147), Expect = 5e-09
Identities = 47/171 (27%), Positives = 74/171 (43%), Gaps = 14/171 (8%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P+P ++W KD + + R + D L + D G+ C A N G A
Sbjct: 35 GNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAA 94
Query: 270 ARL-------CLEAAPK-LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI 321
L C E AP L P + E +E F + + G P P + W DG +
Sbjct: 95 VGLQVDAEAACAEQAPHFLLRPTSIR---VREGSEATF-RCRVGGSPRPAVSWSKDGRRL 150
Query: 322 ITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
D R+ + + S L+I +A+ D G Y+++A+N +G +AA + V
Sbjct: 151 GEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201
Score = 52.4 bits (120), Expect = 8e-06
Identities = 53/226 (23%), Positives = 91/226 (40%), Gaps = 13/226 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H R AL D G + Y E D ++ R +++P VF + L D T E + +
Sbjct: 3061 HVLTLRQLALKDSG-TIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCET 3119
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
S P + W KD + S R ++ + + LL D G KC A G A +
Sbjct: 3120 STCDIP-MCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACS 3174
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + + A P +R+ +D + E L+ + P ++W + + + D+
Sbjct: 3175 SSIVRVHARP-VRFQEALKDLEVLE-GGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYS 3231
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ L + + + D G Y G+ T + +TVTA P
Sbjct: 3232 LRQEGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATLTVTALP 3273
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S PVF+ L++ + V F +G P P++ WFKD + I D+
Sbjct: 5122 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 5181
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ ++P+D G +C A N G + TKA L
Sbjct: 5182 HQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 5214
Score = 48.0 bits (109), Expect = 2e-04
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISI--TPKFSVLKIHSAKRSDRGEYQIQAKN 357
L + G+P P W+ DG ++T+ R + + VLKI K+SDRG Y A N
Sbjct: 257 LSCYVTGEPKPETVWKKDGQ-LVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASN 315
Query: 358 IIGEDTAAFLVTVTAPPDP 376
++G+ ++ LV V P P
Sbjct: 316 LVGQTYSSVLVVVREPAVP 334
Score = 48.0 bits (109), Expect = 2e-04
Identities = 34/136 (25%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ E
Sbjct: 1657 VTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEA---GGQRLSFRLHVAE 1713
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
P++ + L+ + +E I L T+ T+ W DG I R E +
Sbjct: 1714 LEPQISERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDT 1773
Query: 336 SVLKIHSAKRSDRGEY 351
L +H A+ D Y
Sbjct: 1774 HTLTVHGAQVLDSAIY 1789
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/169 (24%), Positives = 70/169 (41%), Gaps = 8/169 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S P V + LE T E V F P + W+KDD + S + ++ + +
Sbjct: 2465 SDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPK-AVQWYKDDTPLSPSEKFKMSLEGQMA 2523
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L +++P+D G +C A G A + + +EA ++ +D E F
Sbjct: 2524 ELRILRLMPADAGVYRCQA----GSAHSSTEVTVEAR-EVTVTGPLQDAEATEEGWASF- 2577
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+ + +EW +G P+ D EIS + L + S +R+D G
Sbjct: 2578 -SCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAG 2625
Score = 46.4 bits (105), Expect = 6e-04
Identities = 35/158 (22%), Positives = 62/158 (39%), Gaps = 8/158 (5%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG V+ E
Sbjct: 1105 VTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEA---GGQRVSFHLHITE 1161
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ + + E T L V +P + W DG + + ++ + +
Sbjct: 1162 PKGVFAKEQSVHNEVQAEAGTTAMLSCE-VAQPQTEVTWYKDGKKLSSSSKVRMEVKGCT 1220
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + ++D GEY +A G +F + +T P
Sbjct: 1221 RRLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEP 1254
Score = 45.6 bits (103), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L IVG PTP + W D P+ R ++ L I D G+Y +A+N I
Sbjct: 29 LSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAI 88
Query: 360 GEDTAAFLVTVTA 372
GE AA + V A
Sbjct: 89 GEAFAAVGLQVDA 101
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/144 (22%), Positives = 56/144 (38%), Gaps = 4/144 (2%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W+KD ++ SS + + T L+ Q+ +D GE C A GG V+
Sbjct: 1193 PQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA---GGQRVSFQL 1249
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
E + + + E + L + T + W DG + + ++ I
Sbjct: 1250 HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEA 1308
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 1309 AGCMRQLVVQQAGQADAGEYTCEA 1332
Score = 45.2 bits (102), Expect = 0.001
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 6105 QVPPRFVNKVLASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 6164
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINETI 298
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + T
Sbjct: 6165 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEVT- 6222
Query: 299 FLKTTIVGKPTPTIE 313
+ T V K T IE
Sbjct: 6223 -EQETKVPKKTVIIE 6236
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 16/156 (10%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
T S+ Q P V ++ L D+ ++ +F + G P+P + WFKD + +S
Sbjct: 5250 TESTTDEGQLPQV-VEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIR 5308
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL------EAAP------KL 280
+T + L + D G+ +N G A + ARL + E P +L
Sbjct: 5309 MTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQL 5368
Query: 281 RYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEW 314
PR E ++ + +I + G+P PT+ W
Sbjct: 5369 VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 5404
Score = 43.2 bits (97), Expect = 0.005
Identities = 53/210 (25%), Positives = 77/210 (36%), Gaps = 18/210 (8%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P FI+ L + A E D S + + W K + R ++ D S L
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D GE C G T A L + A P R ED E E T L+
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPA----RFIEDVKNQEAREGATAVLQ 3822
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ K P +EWR + DR + L+IH +D GEY + G+
Sbjct: 3823 CEL-SKAAP-VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSC----VCGQ 3876
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVT 391
+ + +TV AP R + Q ++ T
Sbjct: 3877 ERTSATLTVRAPQPVFREPLQSLQAEEGST 3906
Score = 41.9 bits (94), Expect = 0.012
Identities = 44/189 (23%), Positives = 76/189 (40%), Gaps = 21/189 (11%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ Q +D GE C A GG ++ L+
Sbjct: 1381 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA---GGQRLS---FSLD 1434
Query: 276 AA-PKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISI 331
A PK+ + + E + E+ TT+ V + + W DG + ++ +
Sbjct: 1435 VAEPKVVFAK--EQPVHREVQAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEA 1492
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQV 386
L + A ++D GEY +A G +F + V P + P + V +
Sbjct: 1493 VGCTRRLVVQQAGQADAGEYSCEA----GSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548
Query: 387 DKSVTLDWE 395
S TL E
Sbjct: 1549 GTSATLSCE 1557
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/190 (24%), Positives = 78/190 (41%), Gaps = 14/190 (7%)
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT-IAWF 219
V S S LTVS R + F+ L V A E + F S PS + WF
Sbjct: 1879 VCESRDDHTSAQLTVSVPRVVK----FMSGLSTVVAEEGGEATFQCVVS--PSDVAVVWF 1932
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
+D + S + AI+ ++ L ++ D G+I A A + A L + AP
Sbjct: 1933 RDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEG----ASSSAALRVREAPV 1988
Query: 280 LRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK 339
L + ++ E + E ++ L+ + +P P + W + + +EI L
Sbjct: 1989 L-FKKKLEPQTVEE-RSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLV 2045
Query: 340 IHSAKRSDRG 349
+H+ +DRG
Sbjct: 2046 LHNVGFADRG 2055
Score = 41.9 bits (94), Expect = 0.012
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PVF + L+ + A E S P+ T+ W K ++ ++ R T+ L+
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCELSE-PTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ D GE CT G T A L + AAP +R+ R+ + + E T L +
Sbjct: 3949 QDLQREDTGEYTCTC----GSQATSATLTVTAAP-VRFLRELQHQEVDE-GGTAHLCCEL 4002
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+ ++EWR + + ++ + L + ++ D G+Y
Sbjct: 4003 -SRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/73 (27%), Positives = 32/73 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P P + W DG P+ I ++ L+I S R D G+Y N +G
Sbjct: 5284 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 5343
Query: 364 AAFLVTVTAPPDP 376
++ + V P +P
Sbjct: 5344 SSARLLVRGPDEP 5356
Score = 39.5 bits (88), Expect = 0.063
Identities = 41/169 (24%), Positives = 65/169 (38%), Gaps = 8/169 (4%)
Query: 189 KRLEDVTALENDKVEFHVTFSG-IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
KRL+ + LE + F S S W + SS R T +L+ +
Sbjct: 2740 KRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREA 2799
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
PSD GE+ + RG +KA L + P + ED + E + L+ +
Sbjct: 2800 APSDAGEVVFSV--RG--LTSKASLIVRERPAAII-KPLEDQWVAP-GEDVELRCELSRA 2853
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
TP + W D I + ++ ++L I A D GEY + +
Sbjct: 2854 GTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 39.5 bits (88), Expect = 0.063
Identities = 24/114 (21%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDE 237
PP ++R + + F V G P PT+ W +++ E ++ T + +
Sbjct: 5370 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 5429
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
L+ + +G C A+N G A+ A L + PK+ + ++ L+
Sbjct: 5430 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 5483
Score = 38.7 bits (86), Expect = 0.11
Identities = 36/139 (25%), Positives = 57/139 (41%), Gaps = 6/139 (4%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
++ A PP R VT ++ ++ +VT G P P W KD + RR + D
Sbjct: 232 AEGAPASPPSTGTRTCTVTEGKHARLSCYVT--GEPKPETVWKKDGQLVTEGRRHVVYED 289
Query: 237 -ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ VL SD G CTA+N G + L + P + + ++ +D + E
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREPAVPFKKRLQDLEVREKE 348
Query: 296 ETIFLKTTIVGKPTPTIEW 314
FL V +P+ W
Sbjct: 349 SATFL--CEVPQPSTEAAW 365
Score = 38.3 bits (85), Expect = 0.15
Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 16/211 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIFSSRRTAITTDESTSVLL 243
P F RL+ + D S S + W K+ E+ + + + + +T LL
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
HQ+ D GE C GG T A L + P++ R D + +E +
Sbjct: 4128 IHQLEAKDTGEYACVT---GGQK-TAASLRV-TEPEVTIVRGLVDAEV-TADEDVEFSCE 4181
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
+ ++W G P+ +++ E+++ + L++ D G +G
Sbjct: 4182 VSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH----LGNH 4237
Query: 363 TAAFLVTVTAPP----DPPRNVSVTRQVDKS 389
++ +TV AP +P ++V ++ D S
Sbjct: 4238 ASSAQLTVRAPEVTILEPLQDVQLSEGQDAS 4268
Score = 37.9 bits (84), Expect = 0.19
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 173 LTVSSDRA-SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
L V ++ A +++ P F+ R + E + F G P P ++W KD +
Sbjct: 97 LQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGP 156
Query: 232 AITTDE--STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 276
+ +E S L P D G + A N G A A L +++
Sbjct: 157 RVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 37.9 bits (84), Expect = 0.19
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P F + L+DV E +KV S P+ + W KD E+ + + AI + L
Sbjct: 2165 PVSFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKAR 271
++ +D+G C A + A K +
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKVQ 2251
Score = 37.9 bits (84), Expect = 0.19
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 1/75 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+P VF+K L+D++A E + S P + W KD ++ S + T L
Sbjct: 2645 KPVVFLKALDDLSAEERGTLALQCEVSD-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703
Query: 243 LFHQILPSDEGEIKC 257
+ H + P D G C
Sbjct: 2704 VVHDVSPEDAGLYTC 2718
Score = 37.5 bits (83), Expect = 0.26
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 12/160 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + L+ Q +D G+ C A RG + +
Sbjct: 1013 VMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEA--RGQRVSFRLHI--- 1067
Query: 276 AAPKLRYPRQYE--DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
PK+ + ++ + + E + L + T + W DG + + ++ + +
Sbjct: 1068 TEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTE-VTWYKDGKKLSSSSKVGMEVKG 1126
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
L + A ++D GEY +A G +F + +T P
Sbjct: 1127 CTRRLVLPQAGKADAGEYSCEA----GGQRVSFHLHITEP 1162
Score = 36.7 bits (81), Expect = 0.45
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 24/239 (10%)
Query: 215 TIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ W K ++F + + D + + LL + D G+ C GH + A L +
Sbjct: 4008 SVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDT----GHTQSMASLSV 4063
Query: 275 EAAPKLRYPRQYEDGLLYEINETIFLKTTIV-GKPTPTIEWRHDGHPIITDDRIEISITP 333
P+ ++ + + L E + L + + ++W +G + + E+
Sbjct: 4064 R-VPRPKFKTRLQ-SLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQG 4121
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR-QVDKSVTL 392
L IH + D GEY G+ TAA L VT P V++ R VD VT
Sbjct: 4122 ATRELLIHQLEAKDTGEYACVTG---GQKTAASL-RVTEP-----EVTIVRGLVDAEVTA 4172
Query: 393 DWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESP 451
D + + C+V TG L+ + + VT + +G + R+K +P
Sbjct: 4173 DEDV---EFSCEVS----RAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTP 4224
Score = 35.5 bits (78), Expect = 1.0
Identities = 40/185 (21%), Positives = 68/185 (36%), Gaps = 13/185 (7%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + I L+ Q +D GE C A GG ++ L +
Sbjct: 1289 VTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA---GGQRLS-FHLDVS 1344
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
+ Q + I + V + + W DG + + ++ +
Sbjct: 1345 EPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCT 1404
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQVDKSV 390
L + A ++D GEY +A G +F + V P + P + V Q S
Sbjct: 1405 RRLVVQQACQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGAST 1460
Query: 391 TLDWE 395
TL E
Sbjct: 1461 TLSCE 1465
Score = 35.5 bits (78), Expect = 1.0
Identities = 31/143 (21%), Positives = 57/143 (39%), Gaps = 10/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ SS + + T L+ + +D GE C A G L +
Sbjct: 1565 VTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHV- 1619
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISIT 332
A PK+ + + E E+ T+ V + + W DG + + ++ +
Sbjct: 1620 AEPKVVFAK--EQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAV 1677
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 1678 GCTRRLVVQQAGQADAGEYSCEA 1700
Score = 35.5 bits (78), Expect = 1.0
Identities = 41/170 (24%), Positives = 63/170 (37%), Gaps = 10/170 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE-STSVLLFHQ 246
I+ LEDV E F S + WF D + ++ I VL Q
Sbjct: 3008 IEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQ 3067
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE-TIFLKTTIV 305
+ D G I A G A L + P + + R+ D + E + T+ +T+
Sbjct: 3068 LALKDSGTIYFEA----GDQRASAALRVTEKPSV-FSRELTDATITEGEDLTLVCETSTC 3122
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
P + W DG + R ++S + L I A D G Y+ +A
Sbjct: 3123 DIP---MCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA 3169
Score = 35.1 bits (77), Expect = 1.4
Identities = 31/144 (21%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNR--GGHAVTKARLC 273
+ W+KD ++ SS + + T L+ Q +D GE C A + H K
Sbjct: 921 VTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKV 980
Query: 274 LEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ A ++ + Q E G N T+ + V + + W DG + + ++ +
Sbjct: 981 VFAKDQVAHSEVQAEAG----ANATLSCE---VAQAQAEVMWYKDGKKLSSSLKVHVEAK 1033
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAK 356
L + A ++D G+Y +A+
Sbjct: 1034 GCRRRLVVQQAGKTDAGDYSCEAR 1057
Score = 34.3 bits (75), Expect = 2.4
Identities = 41/188 (21%), Positives = 71/188 (37%), Gaps = 19/188 (10%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ W+KD ++ S + + T L+ Q +D GE C A G L +
Sbjct: 1473 VMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQADAGEYSCEA----GSQRLSFHLHV- 1527
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTI---VGKPTPTIEWRHDGHPIITDDRIEISIT 332
A PK + + E E+ T+ V + + W DG + + ++ +
Sbjct: 1528 AEPKAVFAK--EQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAV 1585
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP-----PDPPRNVSVTRQVD 387
L + A ++D GEY +A G+ +F + V P + P + V +
Sbjct: 1586 GCTRRLVVQEAGQADAGEYSCKA----GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAG 1641
Query: 388 KSVTLDWE 395
S TL E
Sbjct: 1642 ASATLSCE 1649
Score = 33.9 bits (74), Expect = 3.2
Identities = 45/211 (21%), Positives = 85/211 (40%), Gaps = 14/211 (6%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA-WFKDDYEIF 226
+ DV T + ++ ++ L+DVT +E F S IPS W +
Sbjct: 2362 DAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS-IPSVRPPKWLLGKTVLQ 2420
Query: 227 SSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY 286
+ + + + L+ + + G + T G + + ARL + P + R
Sbjct: 2421 AGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTV----GKSRSSARLVVSDIPVV-LTRPL 2475
Query: 287 EDGLLYEINETIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
E E+ +++ L +P P ++W D P+ ++ ++S+ + + L+I
Sbjct: 2476 EPKTGREL-QSVVLSCDF--RPAPKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMP 2532
Query: 346 SDRGEYQIQAKNIIGE---DTAAFLVTVTAP 373
+D G Y+ QA + A VTVT P
Sbjct: 2533 ADAGVYRCQAGSAHSSTEVTVEAREVTVTGP 2563
Score = 32.3 bits (70), Expect = 9.6
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 9/143 (6%)
Query: 216 IAWFKDDYEIFSSRRTAITTDESTSV-LLFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ W+KD E+ S + D T L+ + DEG C R G RL +
Sbjct: 828 VHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRLRV 883
Query: 275 EAAPKLRYPRQY--EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISIT 332
+ PK+ + ++ L E + L + T + W DG + + ++ + T
Sbjct: 884 -SEPKVVFAKEQLARRKLQAEAGASATLSCEVAQAQTE-VTWYKDGKKLSSSSKVCMEAT 941
Query: 333 PKFSVLKIHSAKRSDRGEYQIQA 355
L + A ++D GEY +A
Sbjct: 942 GCTRRLVVQQAGQADAGEYSCEA 964
Score = 32.3 bits (70), Expect = 9.6
Identities = 36/178 (20%), Positives = 69/178 (38%), Gaps = 8/178 (4%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAI 233
T +S R ++ ++ L D ++ VEF S + + W + S+ T +
Sbjct: 4148 TAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEV 4207
Query: 234 TT-DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
D L + P D G + + + G HA + A+L + AP++ +D L
Sbjct: 4208 AVRDGRIHTLRLKGVTPEDAGTV---SFHLGNHA-SSAQLTVR-APEVTILEPLQDVQLS 4262
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRSDRG 349
E + F + + W G P+ ++ +I++ +L +H D G
Sbjct: 4263 EGQDASF-QCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG 4319
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 79.4 bits (187), Expect = 6e-14
Identities = 88/348 (25%), Positives = 132/348 (37%), Gaps = 18/348 (5%)
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR 190
A +V E+ T L+P H ++ A N G + DV+ V P + K
Sbjct: 377 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV-------RPLIQTKD 429
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDESTSVLLFHQILP 249
E+ + H F P ++W K ++ + RR I + L ++
Sbjct: 430 GENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYEN---GTLQINRTTE 486
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKP 308
D G C N G A L + A KLR P+ L+ + K K
Sbjct: 487 EDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKH 546
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
+ + W DG + + I + L I + D+G Y A + V
Sbjct: 547 SLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQV 606
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAI 424
TV PDPP N+ ++ + ++SV L WE AD + YIVE+ + W L +
Sbjct: 607 TVLDVPDPPENLHLSERQNRSVRLTWEAGADHNS-NISEYIVEFEGNKEEPGRWEELTRV 665
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAID 472
+KT V L L Y+FR+ A + G S PS S P A D
Sbjct: 666 QGKKTTVIL-PLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPD 712
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 8/177 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP +T L+ + + G+P+P + W K ++ R + L
Sbjct: 240 PPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAK---ENYGKTLK 296
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D+G +CTA+N G A + +E P R+ ++ + + Y L
Sbjct: 297 IENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPP--RWTKKPQSAV-YSTGSNGILLCE 353
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
G+P PTI+WR +G P+ + P+ + + + + YQ +A N+ G
Sbjct: 354 AEGEPQPTIKWRVNGSPVDNHPFAGDVVFPR--EISFTNLQPNHTAVYQCEASNVHG 408
Score = 39.1 bits (87), Expect = 0.084
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E + L+ G PTP ++W G + + + LKI + D+G Y+ A
Sbjct: 256 EILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYG---KTLKIENVSYQDKGNYRCTA 312
Query: 356 KNIIGEDTAAFLVTVTAPP 374
N +G T F V V PP
Sbjct: 313 SNFLGTATHDFHVIVEEPP 331
Score = 38.3 bits (85), Expect = 0.15
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 7/154 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q+ P IK+ + A D+ + G P PT +W KD + + I ++ S +
Sbjct: 32 QQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGT 91
Query: 241 VLLFHQ-ILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEINETI 298
+ ++ + +G+ +C A+N+ G A++ + + + PK +P++ D L E + I
Sbjct: 92 FRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPK--FPKEKIDPLEVEEGDPI 149
Query: 299 FLK-TTIVGKPTPTIEWRH-DGHPIITDDRIEIS 330
L G P I W + + I D+R+ +S
Sbjct: 150 VLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMS 183
>AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion
molecule protein.
Length = 1224
Score = 79.4 bits (187), Expect = 6e-14
Identities = 88/348 (25%), Positives = 132/348 (37%), Gaps = 18/348 (5%)
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR 190
A +V E+ T L+P H ++ A N G + DV+ V P + K
Sbjct: 393 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV-------RPLIQTKD 445
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDESTSVLLFHQILP 249
E+ + H F P ++W K ++ + RR I + L ++
Sbjct: 446 GENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYEN---GTLQINRTTE 502
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKP 308
D G C N G A L + A KLR P+ L+ + K K
Sbjct: 503 EDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKH 562
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
+ + W DG + + I + L I + D+G Y A + V
Sbjct: 563 SLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQV 622
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAI 424
TV PDPP N+ ++ + ++SV L WE AD + YIVE+ + W L +
Sbjct: 623 TVLDVPDPPENLHLSERQNRSVRLTWEAGADHNS-NISEYIVEFEGNKEEPGRWEELTRV 681
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAID 472
+KT V L L Y+FR+ A + G S PS S P A D
Sbjct: 682 QGKKTTVIL-PLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPD 728
Score = 52.0 bits (119), Expect = 1e-05
Identities = 45/209 (21%), Positives = 84/209 (40%), Gaps = 14/209 (6%)
Query: 158 LNDVGHSNYSELSDVLTVSSDRASQE------PPVFIKRLEDVTALENDKVEFHVTFSGI 211
+N + H+N S S + ++ Q PP +T L+ + + G+
Sbjct: 224 VNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGL 283
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P+P + W K ++ R + L + D+G +CTA+N G A
Sbjct: 284 PTPQVDWNKIGGDLPKGREAK---ENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFH 340
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
+ +E P R+ ++ + + Y L G+P PTI+WR +G P+ +
Sbjct: 341 VIVEEPP--RWTKKPQSAV-YSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDVV 397
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
P+ + + + + YQ +A N+ G
Sbjct: 398 FPR--EISFTNLQPNHTAVYQCEASNVHG 424
Score = 40.7 bits (91), Expect = 0.027
Identities = 30/110 (27%), Positives = 44/110 (40%), Gaps = 6/110 (5%)
Query: 268 TKARLCLEAAPKLRYPRQY---EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
+KA + PKL P E + E + L+ G PTP ++W G +
Sbjct: 241 SKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKG 300
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ + LKI + D+G Y+ A N +G T F V V PP
Sbjct: 301 REAKENYG---KTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPP 347
Score = 38.3 bits (85), Expect = 0.15
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 7/154 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q+ P IK+ + A D+ + G P PT +W KD + + I ++ S +
Sbjct: 32 QQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGT 91
Query: 241 VLLFHQ-ILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEINETI 298
+ ++ + +G+ +C A+N+ G A++ + + + PK +P++ D L E + I
Sbjct: 92 FRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPK--FPKEKIDPLEVEEGDPI 149
Query: 299 FLK-TTIVGKPTPTIEWRH-DGHPIITDDRIEIS 330
L G P I W + + I D+R+ +S
Sbjct: 150 VLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMS 183
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 79.4 bits (187), Expect = 6e-14
Identities = 88/348 (25%), Positives = 132/348 (37%), Gaps = 18/348 (5%)
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKR 190
A +V E+ T L+P H ++ A N G + DV+ V P + K
Sbjct: 379 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDV-------RPLIQTKD 431
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDESTSVLLFHQILP 249
E+ + H F P ++W K ++ + RR I + L ++
Sbjct: 432 GENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYEN---GTLQINRTTE 488
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKP 308
D G C N G A L + A KLR P+ L+ + K K
Sbjct: 489 EDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKH 548
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
+ + W DG + + I + L I + D+G Y A + V
Sbjct: 549 SLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQV 608
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAI 424
TV PDPP N+ ++ + ++SV L WE AD + YIVE+ + W L +
Sbjct: 609 TVLDVPDPPENLHLSERQNRSVRLTWEAGADHNS-NISEYIVEFEGNKEEPGRWEELTRV 667
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAID 472
+KT V L L Y+FR+ A + G S PS S P A D
Sbjct: 668 QGKKTTVIL-PLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPD 714
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 8/177 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP +T L+ + + G+P+P + W K ++ R + L
Sbjct: 242 PPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREAK---ENYGKTLK 298
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D+G +CTA+N G A + +E P R+ ++ + + Y L
Sbjct: 299 IENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPP--RWTKKPQSAV-YSTGSNGILLCE 355
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
G+P PTI+WR +G P+ + P+ + + + + YQ +A N+ G
Sbjct: 356 AEGEPQPTIKWRVNGSPVDNHPFAGDVVFPR--EISFTNLQPNHTAVYQCEASNVHG 410
Score = 39.1 bits (87), Expect = 0.084
Identities = 23/79 (29%), Positives = 34/79 (43%), Gaps = 3/79 (3%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E + L+ G PTP ++W G + + + LKI + D+G Y+ A
Sbjct: 258 EILLLECFAEGLPTPQVDWNKIGGDLPKGREAKENYG---KTLKIENVSYQDKGNYRCTA 314
Query: 356 KNIIGEDTAAFLVTVTAPP 374
N +G T F V V PP
Sbjct: 315 SNFLGTATHDFHVIVEEPP 333
Score = 38.3 bits (85), Expect = 0.15
Identities = 37/154 (24%), Positives = 71/154 (46%), Gaps = 7/154 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q+ P IK+ + A D+ + G P PT +W KD + + I ++ S +
Sbjct: 34 QQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGT 93
Query: 241 VLLFHQ-ILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEINETI 298
+ ++ + +G+ +C A+N+ G A++ + + + PK +P++ D L E + I
Sbjct: 94 FRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPK--FPKEKIDPLEVEEGDPI 151
Query: 299 FLK-TTIVGKPTPTIEWRH-DGHPIITDDRIEIS 330
L G P I W + + I D+R+ +S
Sbjct: 152 VLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMS 185
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 77.8 bits (183), Expect = 2e-13
Identities = 82/293 (27%), Positives = 118/293 (40%), Gaps = 32/293 (10%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYE--IFSSRRTAITTDESTSV---LLFHQILPSDEGEIK 256
V F +G P P I W ++ + +FS + ++ S S L + SD G
Sbjct: 3 VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYI 62
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE---INETIFLKTTIVGKPTPTIE 313
C N G +TKA L + R P G + + ++ T L G P PTI
Sbjct: 63 CQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTIL 122
Query: 314 WRHDGHPIIT-DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT-AAFL---- 367
WR DG + T D RI+ + VL+I AK D G Y A GE T +A++
Sbjct: 123 WRKDGVLVSTQDSRIK---QLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQG 179
Query: 368 ------VTVTAP--------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY 413
V V P P P VT +VTL W+P + G I +
Sbjct: 180 KVNEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFS 239
Query: 414 RTGWNVWLKAITSRKTNVT-LFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR 465
+ W + KT + + L + Y F ++A + YG+S PS S PV+
Sbjct: 240 HASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVK 292
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIV 135
P+ P KP++ +D N +TL W P + G P Y +E + + W +T V
Sbjct: 200 PSAPSKPEV----TDVSRNTVTLSWQPNLNSGATPT-SYIIEAFSHASGSSW-QTVAENV 253
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GL+P Y F V A N G S+ S++SD
Sbjct: 254 KTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 289
Score = 37.9 bits (84), Expect = 0.19
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEY 351
T+ + G P P I WR +G + + +FSV L I + +RSD G Y
Sbjct: 2 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 61
Query: 352 QIQAKNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLD 393
Q N+ G T A+L D P V V+++V +D
Sbjct: 62 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVD 104
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 77.8 bits (183), Expect = 2e-13
Identities = 76/297 (25%), Positives = 123/297 (41%), Gaps = 28/297 (9%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
I +E+ TA+E ++V SG P P+I W I S + + T E L H
Sbjct: 310 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHM 369
Query: 247 ILPS---------------DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
++ S D GE CTA+N G L ++ APKL+ P
Sbjct: 370 VVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YT 426
Query: 292 YEINETIFLKTTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+E N+ + + + P+ TI W DG P I+I TP S L++ +D G
Sbjct: 427 WEGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 485
Query: 350 EYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYI 409
Y A N IG+++ F++ P P ++ + + ++ P GG + Y
Sbjct: 486 NYNCTAVNRIGQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYK 544
Query: 410 VEYYRTGWNVW-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
E+ G VW K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 545 AEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 601
Score = 65.7 bits (153), Expect = 8e-10
Identities = 59/210 (28%), Positives = 83/210 (39%), Gaps = 23/210 (10%)
Query: 184 PPVFIKRLEDVTALEN--DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDEST 239
PP R V A N V G P PT++W KD +I I +D+S
Sbjct: 211 PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS- 269
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L ++ +DE E C A N+ G L + A PK+ Y E+ E+ E +
Sbjct: 270 SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAMELEEQVT 326
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS------------- 346
L G P P+I WR I ++++ + K L H RS
Sbjct: 327 LTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQ 386
Query: 347 --DRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D GEY A N IG+D+ + + V P
Sbjct: 387 YTDAGEYICTASNTIGQDSQSMYLEVQYAP 416
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 21/190 (11%)
Query: 216 IAWFKDDYEIFS---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+WF + E + R + + D+S+S L + D G KC T G + ++A +
Sbjct: 52 ISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDG-SESEATV 110
Query: 273 CLEAAPKLRY-----PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ KL + P+++ +G E + +V PTI W+H G +I +
Sbjct: 111 NVKIFQKLMFKNAPTPQEFREG------EDAVIVCDVVSSLPPTIIWKHKGRDVILKKDV 164
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNII-GE-DTAAFLVTVTAPP--DPPRN-VSV 382
+ + L+I K++D G Y+ + + + GE + V V PP +N V+
Sbjct: 165 RFIVLSN-NYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNA 223
Query: 383 TRQVDKSVTL 392
T + +SVTL
Sbjct: 224 TANLGQSVTL 233
Score = 47.6 bits (108), Expect = 2e-04
Identities = 49/195 (25%), Positives = 78/195 (40%), Gaps = 7/195 (3%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT--NRGGHA 266
S +P PTI W ++ + S + L I +DEG +C RG
Sbjct: 143 SSLP-PTIIWKHKGRDVILKKDVRFIV-LSNNYLQIRGIKKTDEGTYRCEGRILARGEIN 200
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ + P ++ RQ + +++ L G P PT+ W DG I ++
Sbjct: 201 FKDIQVIVNVPPTIQ-ARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEED 259
Query: 327 IEISI-TPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT-R 384
E I + S L I ++D EY A+N GE A + V A P + T
Sbjct: 260 DEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAM 319
Query: 385 QVDKSVTLDWEPPAD 399
++++ VTL E D
Sbjct: 320 ELEEQVTLTCEASGD 334
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 507 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 561
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 562 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 605
>BC014205-1|AAH14205.2| 601|Homo sapiens NCAM1 protein protein.
Length = 601
Score = 77.8 bits (183), Expect = 2e-13
Identities = 76/297 (25%), Positives = 123/297 (41%), Gaps = 28/297 (9%)
Query: 188 IKRLEDVTALE-NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
I +E+ TA+E ++V SG P P+I W I S + + T E L H
Sbjct: 53 ITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHM 112
Query: 247 ILPS---------------DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
++ S D GE CTA+N G L ++ APKL+ P
Sbjct: 113 VVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAV---YT 169
Query: 292 YEINETIFLKTTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRG 349
+E N+ + + + P+ TI W DG P I+I TP S L++ +D G
Sbjct: 170 WEGNQ-VNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFG 228
Query: 350 EYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYI 409
Y A N IG+++ F++ P P ++ + + ++ P GG + Y
Sbjct: 229 NYNCTAVNRIGQESLEFILVQADTPSSP-SIDQVEPYSSTAQVQFDEPEATGGVPILKYK 287
Query: 410 VEYYRTGWNVW-LKAITSRKTN----VTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
E+ G VW K +++ + VT+ L + Y R+ A + G+ S+ S
Sbjct: 288 AEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAAS 344
Score = 51.2 bits (117), Expect = 2e-05
Identities = 44/157 (28%), Positives = 65/157 (41%), Gaps = 19/157 (12%)
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLY 292
I +D+S S L ++ +DE E C A N+ G L + A PK+ Y E+
Sbjct: 7 IFSDDS-SQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITY---VENQTAM 62
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRS------ 346
E+ E + L G P P+I WR I ++++ + K L H RS
Sbjct: 63 ELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSS 122
Query: 347 ---------DRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D GEY A N IG+D+ + + V P
Sbjct: 123 LTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAP 159
Score = 33.9 bits (74), Expect = 3.2
Identities = 29/104 (27%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRT--- 130
A P+ P Q+ P S + + AT GG P+ Y+ E +G W
Sbjct: 250 ADTPSSPSIDQVEPYSSTAQ---VQFDEPEAT--GGVPILKYKAEWRAVGEEVWHSKWYD 304
Query: 131 APPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
A + + + GL+P Y R+AALN G S S+ T
Sbjct: 305 AKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKT 348
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 77.8 bits (183), Expect = 2e-13
Identities = 73/290 (25%), Positives = 116/290 (40%), Gaps = 15/290 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ + + L
Sbjct: 424 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LE 481
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + RL E R R ED + T+ L+
Sbjct: 482 IKMIRKEDQGIYTCVATNILGKAENQVRL--EVKDPTRIYRMPEDQVARR-GTTVQLECR 538
Query: 304 IVGKPTP--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 539 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 594
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--NV 419
D A +TV PD PR++ +T ++SV L W P D + +Y+V++ + V
Sbjct: 595 DLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV 653
Query: 420 WL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
W + N + L Y+FR+ A + G S PS S R G
Sbjct: 654 WHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSG 703
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 265 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 321
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 322 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 378
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 379 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 431
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 17/184 (9%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+PSP I W E + + ++ + + + +L + + C A H + +
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKR-VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 219
Query: 270 ----------ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
R E P YP+ + + L+ G PTP I W G
Sbjct: 220 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 279
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DP 376
+ D+ + K L+I + D GEY A N +G V V A P D
Sbjct: 280 D-LPSDKAKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 336
Query: 377 PRNV 380
P+N+
Sbjct: 337 PKNL 340
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 911 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 969
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 970 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1003
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 77.8 bits (183), Expect = 2e-13
Identities = 73/290 (25%), Positives = 116/290 (40%), Gaps = 15/290 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ + + L
Sbjct: 441 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LE 498
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + RL E R R ED + T+ L+
Sbjct: 499 IKMIRKEDQGIYTCVATNILGKAENQVRL--EVKDPTRIYRMPEDQVARR-GTTVQLECR 555
Query: 304 IVGKPTP--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 556 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--NV 419
D A +TV PD PR++ +T ++SV L W P D + +Y+V++ + V
Sbjct: 612 DLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV 670
Query: 420 WL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
W + N + L Y+FR+ A + G S PS S R G
Sbjct: 671 WHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSG 720
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 282 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 338
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 339 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 395
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 396 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 448
Score = 39.1 bits (87), Expect = 0.084
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
AR E P YP+ + + L+ G PTP I W G + D+ +
Sbjct: 247 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD-LPSDKAKF 305
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNV 380
K L+I + D GEY A N +G V V A P D P+N+
Sbjct: 306 ENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNL 357
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 928 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 986
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 987 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1020
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 77.8 bits (183), Expect = 2e-13
Identities = 73/290 (25%), Positives = 116/290 (40%), Gaps = 15/290 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ + + L
Sbjct: 238 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LE 295
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + RL E R R ED + T+ L+
Sbjct: 296 IKMIRKEDQGIYTCVATNILGKAENQVRL--EVKDPTRIYRMPEDQVARR-GTTVQLECR 352
Query: 304 IVGKPTP--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 353 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 408
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--NV 419
D A +TV PD PR++ +T ++SV L W P D + +Y+V++ + V
Sbjct: 409 DLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV 467
Query: 420 WL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
W + N + L Y+FR+ A + G S PS S R G
Sbjct: 468 WHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSG 517
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 79 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 135
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 136 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 192
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 193 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 245
Score = 38.3 bits (85), Expect = 0.15
Identities = 32/117 (27%), Positives = 44/117 (37%), Gaps = 6/117 (5%)
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
V R E P YP+ + + L+ G PTP I W G + D+
Sbjct: 41 VLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD-LPSDK 99
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNV 380
+ K L+I + D GEY A N +G V V A P D P+N+
Sbjct: 100 AKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNL 154
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 725 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 783
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 784 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 817
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 77.8 bits (183), Expect = 2e-13
Identities = 73/290 (25%), Positives = 116/290 (40%), Gaps = 15/290 (5%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ + + L
Sbjct: 494 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LE 551
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + RL E R R ED + T+ L+
Sbjct: 552 IKMIRKEDQGIYTCVATNILGKAENQVRL--EVKDPTRIYRMPEDQVARR-GTTVQLECR 608
Query: 304 IVGKPTP--TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 609 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 664
Query: 362 DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--NV 419
D A +TV PD PR++ +T ++SV L W P D + +Y+V++ + V
Sbjct: 665 DLAKAYLTVLGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPITDYVVQFEEDQFQPGV 723
Query: 420 WL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
W + N + L Y+FR+ A + G S PS S R G
Sbjct: 724 WHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSG 773
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 335 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 391
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 392 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 448
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 449 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 501
Score = 39.1 bits (87), Expect = 0.084
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
AR E P YP+ + + L+ G PTP I W G + D+ +
Sbjct: 300 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD-LPSDKAKF 358
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNV 380
K L+I + D GEY A N +G V V A P D P+N+
Sbjct: 359 ENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNL 410
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 981 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 1039
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 1040 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1073
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 77.4 bits (182), Expect = 3e-13
Identities = 71/259 (27%), Positives = 110/259 (42%), Gaps = 18/259 (6%)
Query: 209 SGIPSPTIAWFKDDYEIFSSR---RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
SG P P I WFKD + +S R ES L Q SD+G+ +C ATN G
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGT 209
Query: 266 AVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHP 320
+ A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 RYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAED 269
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
+ +D + I +VL+++ ++S Y A + +G A +TV A P PP
Sbjct: 270 LTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALPKPPGTP 323
Query: 381 SVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEG 439
VT S+TL W+ + V YI+++ K I T ++ L
Sbjct: 324 VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPY 380
Query: 440 SEYKFRIKAESPYGMSAPS 458
S+Y+FR+ A + G PS
Sbjct: 381 SDYEFRVVAVNNIGRGPPS 399
Score = 60.9 bits (141), Expect = 2e-08
Identities = 51/191 (26%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRG 349
E T + G P P I W D P+ T + RI+ + L+I ++ SD+G
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQG 197
Query: 350 EYQIQAKNIIG 360
+Y+ A N G
Sbjct: 198 KYECVATNSAG 208
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 503 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 558
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 559 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 595
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 317 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 369
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 370 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 415
Score = 33.1 bits (72), Expect = 5.5
Identities = 67/334 (20%), Positives = 126/334 (37%), Gaps = 29/334 (8%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G + YS +++ + PP F + + V G
Sbjct: 198 KYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGS 256
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P P + W ++ I +VL + + S C A + G A+
Sbjct: 257 PMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANYTCVAMSTLGVIEAIAQ 310
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE 328
+ ++A PK ++ E T T G P P + P +++ I+
Sbjct: 311 ITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEID 365
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT---APPDPPRNVSVTR 384
T ++SV + + SD E+++ A N IG + ++T T AP PR+V
Sbjct: 366 GVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARM 422
Query: 385 QVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAITSRKTNVTLFDLIEGSE 441
++ + W+ P + G ++ Y V Y N W+K + T+ +L+
Sbjct: 423 LSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKT 481
Query: 442 YKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
Y ++ A + G SS+ + +PG+ ++
Sbjct: 482 YSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 515
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 77.0 bits (181), Expect = 3e-13
Identities = 83/334 (24%), Positives = 135/334 (40%), Gaps = 18/334 (5%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L ++GL P F+ A N G S V +++ P + D T ++
Sbjct: 42 LQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIA--------PNITRGPLDSTVIDG 93
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSS--RRTAITTDESTSVLLFHQILPSDEGEIKC 257
V SG P P I W K + + S + T ES S+L+ + SD G C
Sbjct: 94 MSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI-SDAGTYTC 152
Query: 258 TATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHD 317
ATN G A L + A ++ P Q + ++ ++ T + T W D
Sbjct: 153 LATNSRGVDEASADLVVWARTRITKPPQ-DQSVIKGTQASMVCGVTHDPRVTIRYIWEKD 211
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPP 377
G + T+ I + S L I D G Y + + G D+ + + V P P
Sbjct: 212 GATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAP 270
Query: 378 RN-VSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTG--WNVWLKAITSRKTNVTL 433
+ V+ V++ ++ L W P D G + YI+E W V L ++ + T+VT+
Sbjct: 271 EHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDPKATSVTV 329
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
L+ Y+FR+ A + G S ++ V +P
Sbjct: 330 KGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLP 363
Score = 62.5 bits (145), Expect = 8e-09
Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW-IRTAPPI 134
RP PP +P + D ++ L W P + DG +P+R Y ++ L S W + +A
Sbjct: 1076 RPQPPSRPMVQQ--EDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVS 1132
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
++ L+P Y+FRV A ND+G S +SE S+ LT + P +
Sbjct: 1133 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1184
Score = 54.0 bits (124), Expect = 3e-06
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 11/187 (5%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+P P+I W+KD + + T + L ++P D G +C A N G T
Sbjct: 11 GVPPPSITWYKDAAVVEVEKLTRF-RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 69
Query: 270 ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L + + AP + R D + + ++ L G P P I W+ G I+ ++
Sbjct: 70 TYLAVTSIAPNI--TRGPLDSTVID-GMSVVLACETSGAPRPAITWQ-KGERILASGSVQ 125
Query: 329 I-SITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV---TAPPDPPRNVSVT 383
+ TP + L I SD G Y A N G D A+ + V T PP++ SV
Sbjct: 126 LPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVI 185
Query: 384 RQVDKSV 390
+ S+
Sbjct: 186 KGTQASM 192
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 67 KNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE 126
++ H + P P P + LS E AI L W DG +PL Y +E + +
Sbjct: 257 RSAHLRVRQLPHAPEHP--VATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 313
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP 184
+ A + + GL P YQFR+ A+NDVG +S+ ++ +++ + + P
Sbjct: 314 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 371
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 11/149 (7%)
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-----DTAAFLVTVTAPPDPPRNVSVTR 384
S+ PK + + + + ++++ A N +G+ DT + P PP+NV +
Sbjct: 319 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 378
Query: 385 QVDKSVTLDWEPPAD--DGGCKVGNYIVEYYRTGWNV--WLKAITSRK-TNVTLFDLIEG 439
+ ++S+ + W+PP + G G YI+ Y G V K IT N+ L DLI
Sbjct: 379 RTNQSIMIQWQPPPESHQNGILKG-YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 437
Query: 440 SEYKFRIKAESPYGMSAPSSESSPVRIPG 468
+ Y+ + A + G+ SS+ + + G
Sbjct: 438 TNYEIEVAAYNSAGLGVYSSKVTEWTLQG 466
Score = 39.5 bits (88), Expect = 0.063
Identities = 39/120 (32%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP- 138
PG P I + + ++ L W P G L YQ+ +RL +T TA VL P
Sbjct: 978 PGPPMGI-LFPEVRTTSVRLIWQPPAAPNGIIL-AYQIT-HRLNTTT-ANTATVEVLAPS 1033
Query: 139 --ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ TGL+P Y FR+ A G +E V T DR Q P + + EDV A
Sbjct: 1034 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRA 1092
Score = 37.5 bits (83), Expect = 0.26
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 360 GEDTAAFLVTVTAP--PDPPRNVSVTRQV--DKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
GE A +VT P PP V ++ +SV L WEP DG V Y ++
Sbjct: 1061 GEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTREL 1119
Query: 416 GWNVWLKAITSRKTNVTLF--DLIEG-SEYKFRIKAESPYGMSAPSSES 461
W S N + F D ++ + YKFR+KA + G S S ES
Sbjct: 1120 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1168
Score = 36.7 bits (81), Expect = 0.45
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
Query: 350 EYQIQAKNIIGE----DTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWEPPADD 400
+++++A N IG+ + + L T+ A PD P +SVT SV + W+PPA+D
Sbjct: 1150 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAED 1205
Score = 35.1 bits (77), Expect = 1.4
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SR 427
T A P P +V + SV + WE P G G +V + + K +T
Sbjct: 1396 TQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDV 1455
Query: 428 KTNVTLF----DLIEGSEYKFRIKAES-PYGMSAPSSESSPVRIPG 468
K N L+ DL EG Y+FRI+A++ YG P E++ PG
Sbjct: 1456 KGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG---PEIEANVTTGPG 1498
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 76.6 bits (180), Expect = 5e-13
Identities = 76/292 (26%), Positives = 121/292 (41%), Gaps = 20/292 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I+WFKD + + + L SD+G+ +C ATN G +
Sbjct: 150 GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSA 209
Query: 270 -ARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + AP+ P ++ + ++ L VG P P ++W + +D
Sbjct: 210 PANLYVRVRRVAPRFSIPPSSQEVMP---GGSVNLTCVAVGAPMPYVKWMMGAEELTKED 266
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
+ + +VL++ + RS Y A + +G A VTV A P PP ++ VT
Sbjct: 267 EMPVGR----NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTET 320
Query: 386 VDKSVTLDWEPPADDGGCK-VGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYK 443
SVTL W D G + V Y ++Y G + + T ++ L SEY
Sbjct: 321 TATSVTLTW----DSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYA 376
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
FR+ A + G P SE+ R +A V+AR+++ + E P
Sbjct: 377 FRVLAVNSIG-RGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 427
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 23 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 82
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 83 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 141
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 142 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 198
Query: 355 AKNIIG 360
A N G
Sbjct: 199 ATNSAG 204
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRK 428
AP PPR V ++ + WEPP + G V Y V Y R N W K T
Sbjct: 402 APSSPPRRVQARMLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAG 460
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
T+ L+ G Y R+ A + G PS
Sbjct: 461 LLTTVGSLLPGITYSLRVLAFTAVGDGPPS 490
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 82 KPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELV 141
KP I ++++ ++TL W + P+ Y ++ G TE V
Sbjct: 310 KPPIDLVVTETTATSVTLTWDSGNSE---PVTYYGIQYRAAG-TEGPFQEVDGVATTRYS 365
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y FRV A+N +G SE V + ++A PP
Sbjct: 366 IGGLSPFSEYAFRVLAVNSIGRGPPSEA--VRARTGEQAPSSPP 407
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 76.6 bits (180), Expect = 5e-13
Identities = 76/292 (26%), Positives = 121/292 (41%), Gaps = 20/292 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I+WFKD + + + L SD+G+ +C ATN G +
Sbjct: 160 GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSA 219
Query: 270 -ARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + AP+ P ++ + ++ L VG P P ++W + +D
Sbjct: 220 PANLYVRVRRVAPRFSIPPSSQEVMP---GGSVNLTCVAVGAPMPYVKWMMGAEELTKED 276
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
+ + +VL++ + RS Y A + +G A VTV A P PP ++ VT
Sbjct: 277 EMPVGR----NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTET 330
Query: 386 VDKSVTLDWEPPADDGGCK-VGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYK 443
SVTL W D G + V Y ++Y G + + T ++ L SEY
Sbjct: 331 TATSVTLTW----DSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYA 386
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
FR+ A + G P SE+ R +A V+AR+++ + E P
Sbjct: 387 FRVLAVNSIG-RGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRK 428
AP PPR V ++ + WEPP + G V Y V Y R N W K T
Sbjct: 412 APSSPPRRVQARMLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAG 470
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
T+ L+ G Y R+ A + G PS
Sbjct: 471 LLTTVGSLLPGITYSLRVLAFTAVGDGPPS 500
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 82 KPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELV 141
KP I ++++ ++TL W + P+ Y ++ G TE V
Sbjct: 320 KPPIDLVVTETTATSVTLTWDSGNSE---PVTYYGIQYRAAG-TEGPFQEVDGVATTRYS 375
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y FRV A+N +G SE V + ++A PP
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEA--VRARTGEQAPSSPP 417
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEYYRT-----GWNVWLKAI 424
+ P PP+ V +V + W PPAD + Y V Y G +V + I
Sbjct: 604 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHV-VDGI 662
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ ++ L L + +EY+ ++A + G P ESSPV +
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLV 701
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 76.6 bits (180), Expect = 5e-13
Identities = 87/337 (25%), Positives = 127/337 (37%), Gaps = 38/337 (11%)
Query: 167 SELSDVLTVSSDRASQEP---PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S D LT S+ R + P P+F + LEDV LE F SG P P + W
Sbjct: 915 STAKDELTCSA-RLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGC 973
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA------- 276
+ S + D L + DEG +A N G A A+L +E
Sbjct: 974 PMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG 1033
Query: 277 -APKLR----YPRQYEDGLLYEINETIFLKTT----------------IVGKPTPTIEWR 315
+ KL P + E G L ++ FL+ + G P PTI W
Sbjct: 1034 PSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWF 1093
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPP 374
H+GH I + D ++ L + G Y+ N +G+ A L P
Sbjct: 1094 HNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVP 1153
Query: 375 DPPRNV-SVTRQVDKSVTLDWEPPAD-DGGCKVGN--YIVEYYRTGWNVWLKAITS-RKT 429
PP V + VTL W PP D + Y V++ G + W +T R+
Sbjct: 1154 GPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREP 1213
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
L +G ++ FR+ + + S PS S PV++
Sbjct: 1214 GWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQL 1250
Score = 66.1 bits (154), Expect = 6e-10
Identities = 75/294 (25%), Positives = 110/294 (37%), Gaps = 19/294 (6%)
Query: 77 PAPP-GKPQIIPILSDDEPNAITLKWAPATHDGGA---PLRGYQVECNRLGSTEWIRTAP 132
P PP G PQ++ + +TL W P A Y V+ LGS +W TA
Sbjct: 1153 PGPPDGAPQVVAVTG----RMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQW--TAL 1206
Query: 133 PIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKR 190
LR P TGL ++ FRV + S S S+ V + +E P + +
Sbjct: 1207 VTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDK 1266
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT---DESTSVLLFHQI 247
+ V +E VTF+ + + + W + +R D+ L ++
Sbjct: 1267 PDIVYVVEGQPASVTVTFNHVEAQVV-WRSCRGALLEARAGVYELSQPDDDQYCLRICRV 1325
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
D G + CTA NR H + LE A R+ ED + ET + GK
Sbjct: 1326 SRRDMGALTCTARNR--HGTQTCSVTLELAEAPRFESIMED-VEVGAGETARFAVVVEGK 1382
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W D + + L + S D G Y A+N+ GE
Sbjct: 1383 PLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGE 1436
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/95 (30%), Positives = 40/95 (42%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F +EDV + F V G P P I W+KD+ + S + +E+ L
Sbjct: 1354 EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSL 1413
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G CTA N G KA L + +A
Sbjct: 1414 VVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1448
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/105 (29%), Positives = 42/105 (40%)
Query: 168 ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS 227
E SD VS+ E PVF L++V V + P P ++W KD + S
Sbjct: 576 ESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRS 635
Query: 228 SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
R + + LL + +D G TATN G A A L
Sbjct: 636 EGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASL 680
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/73 (28%), Positives = 35/73 (47%)
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ LK I P P + W DG + ++ R+ + + L + A+ +D G Y A N
Sbjct: 610 VLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATN 669
Query: 358 IIGEDTAAFLVTV 370
+G+ T A +TV
Sbjct: 670 ELGQATCAASLTV 682
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 5/109 (4%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
SSD S+ PP F L D + E V + G P P ++W ++ + +R
Sbjct: 731 SSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRR--FA 788
Query: 236 DESTSVLLFHQILPSDEGE---IKCTATNRGGHAVTKARLCLEAAPKLR 281
+E+ L +IL ++ G+ C A N G +ARL + A P+ R
Sbjct: 789 EEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESR 837
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 9/165 (5%)
Query: 308 PTPTIEWRHDGHPIITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W D + ++ + I S +L I A + G Y+ A N++G T++
Sbjct: 2482 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2541
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW---LKA 423
V V P VT+ + + W+P C Y +E G +VW
Sbjct: 2542 TVAVARVPGKLAPPEVTQTYQDTALVLWKPGDSRAPC---TYTLERRVDGESVWHPVSSG 2598
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
I NVT L G +FR+ + G S+ S V + G
Sbjct: 2599 IPDCYYNVT--HLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRG 2641
Score = 39.9 bits (89), Expect = 0.048
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 6/144 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT-DEST 239
S PPVF +L+D LE + + P+P I+W KD + S I + +
Sbjct: 2451 SDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR 2510
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETI 298
+L + G +C+ATN G + + + P KL P E Y+ +
Sbjct: 2511 QLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPP---EVTQTYQDTALV 2567
Query: 299 FLKTTIVGKP-TPTIEWRHDGHPI 321
K P T T+E R DG +
Sbjct: 2568 LWKPGDSRAPCTYTLERRVDGESV 2591
Score = 39.1 bits (87), Expect = 0.084
Identities = 31/132 (23%), Positives = 46/132 (34%), Gaps = 1/132 (0%)
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
LL + D G C + ARL + + + R ED + E F
Sbjct: 897 LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARF-D 955
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P P + W H G P+ + + + L I D G Y + A N G+
Sbjct: 956 CKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQ 1015
Query: 362 DTAAFLVTVTAP 373
+ + V P
Sbjct: 1016 AHCSAQLYVEEP 1027
Score = 34.3 bits (75), Expect = 2.4
Identities = 20/81 (24%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
+ + + + G+P P + W + P+ D R L+I +A+R D G Y +
Sbjct: 755 QDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCK 814
Query: 355 AKNIIGEDTAAFLVTVTAPPD 375
A N G + V A P+
Sbjct: 815 AVNEYGARQCEARLEVRAHPE 835
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 76.6 bits (180), Expect = 5e-13
Identities = 76/292 (26%), Positives = 121/292 (41%), Gaps = 20/292 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I+WFKD + + + L SD+G+ +C ATN G +
Sbjct: 160 GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSA 219
Query: 270 -ARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + AP+ P ++ + ++ L VG P P ++W + +D
Sbjct: 220 PANLYVRVRRVAPRFSIPPSSQEVMP---GGSVNLTCVAVGAPMPYVKWMMGAEELTKED 276
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
+ + +VL++ + RS Y A + +G A VTV A P PP ++ VT
Sbjct: 277 EMPVGR----NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTET 330
Query: 386 VDKSVTLDWEPPADDGGCK-VGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYK 443
SVTL W D G + V Y ++Y G + + T ++ L SEY
Sbjct: 331 TATSVTLTW----DSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYA 386
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
FR+ A + G P SE+ R +A V+AR+++ + E P
Sbjct: 387 FRVLAVNSIG-RGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRK 428
AP PPR V ++ + WEPP + G V Y V Y R N W K T
Sbjct: 412 APSSPPRRVQARMLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAG 470
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
T+ L+ G Y R+ A + G PS
Sbjct: 471 LLTTVGSLLPGITYSLRVLAFTAVGDGPPS 500
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 82 KPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELV 141
KP I ++++ ++TL W + P+ Y ++ G TE V
Sbjct: 320 KPPIDLVVTETTATSVTLTWDSGNSE---PVTYYGIQYRAAG-TEGPFQEVDGVATTRYS 375
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y FRV A+N +G SE V + ++A PP
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEA--VRARTGEQAPSSPP 417
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEYYRT-----GWNVWLKAI 424
+ P PP+ V +V + W PPAD + Y V Y G +V + I
Sbjct: 604 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHV-VDGI 662
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ ++ L L + +EY+ ++A + G P ESSPV +
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLV 701
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 76.6 bits (180), Expect = 5e-13
Identities = 76/292 (26%), Positives = 121/292 (41%), Gaps = 20/292 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I+WFKD + + + L SD+G+ +C ATN G +
Sbjct: 160 GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSA 219
Query: 270 -ARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + AP+ P ++ + ++ L VG P P ++W + +D
Sbjct: 220 PANLYVRVRRVAPRFSIPPSSQEVMP---GGSVNLTCVAVGAPMPYVKWMMGAEELTKED 276
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
+ + +VL++ + RS Y A + +G A VTV A P PP ++ VT
Sbjct: 277 EMPVGR----NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTET 330
Query: 386 VDKSVTLDWEPPADDGGCK-VGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYK 443
SVTL W D G + V Y ++Y G + + T ++ L SEY
Sbjct: 331 TATSVTLTW----DSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYA 386
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
FR+ A + G P SE+ R +A V+AR+++ + E P
Sbjct: 387 FRVLAVNSIG-RGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 437
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRK 428
AP PPR V ++ + WEPP + G V Y V Y R N W K T
Sbjct: 412 APSSPPRRVQARMLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAG 470
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
T+ L+ G Y R+ A + G PS
Sbjct: 471 LLTTVGSLLPGITYSLRVLAFTAVGDGPPS 500
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 82 KPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELV 141
KP I ++++ ++TL W + P+ Y ++ G TE V
Sbjct: 320 KPPIDLVVTETTATSVTLTWDSGNSE---PVTYYGIQYRAAG-TEGPFQEVDGVATTRYS 375
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y FRV A+N +G SE V + ++A PP
Sbjct: 376 IGGLSPFSEYAFRVLAVNSIGRGPPSEA--VRARTGEQAPSSPP 417
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEYYRT-----GWNVWLKAI 424
+ P PP+ V +V + W PPAD + Y V Y G +V + I
Sbjct: 604 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHV-VDGI 662
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ ++ L L + +EY+ ++A + G P ESSPV +
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLV 701
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 76.6 bits (180), Expect = 5e-13
Identities = 76/292 (26%), Positives = 121/292 (41%), Gaps = 20/292 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I+WFKD + + + L SD+G+ +C ATN G +
Sbjct: 180 GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSA 239
Query: 270 -ARLCLEA---APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + AP+ P ++ + ++ L VG P P ++W + +D
Sbjct: 240 PANLYVRVRRVAPRFSIPPSSQEVMP---GGSVNLTCVAVGAPMPYVKWMMGAEELTKED 296
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
+ + +VL++ + RS Y A + +G A VTV A P PP ++ VT
Sbjct: 297 EMPVGR----NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTET 350
Query: 386 VDKSVTLDWEPPADDGGCK-VGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEYK 443
SVTL W D G + V Y ++Y G + + T ++ L SEY
Sbjct: 351 TATSVTLTW----DSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYA 406
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
FR+ A + G P SE+ R +A V+AR+++ + E P
Sbjct: 407 FRVLAVNSIG-RGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPP 457
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 53 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 112
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 113 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 171
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 172 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 228
Query: 355 AKNIIG 360
A N G
Sbjct: 229 ATNSAG 234
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/90 (32%), Positives = 37/90 (41%), Gaps = 4/90 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRK 428
AP PPR V ++ + WEPP + G V Y V Y R N W K T
Sbjct: 432 APSSPPRRVQARMLSASTMLVQWEPPEEPNGL-VRGYRVYYTPDSRRPPNAWHKHNTDAG 490
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
T+ L+ G Y R+ A + G PS
Sbjct: 491 LLTTVGSLLPGITYSLRVLAFTAVGDGPPS 520
Score = 35.5 bits (78), Expect = 1.0
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
Query: 82 KPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELV 141
KP I ++++ ++TL W + P+ Y ++ G TE V
Sbjct: 340 KPPIDLVVTETTATSVTLTWDSGNSE---PVTYYGIQYRAAG-TEGPFQEVDGVATTRYS 395
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y FRV A+N +G SE V + ++A PP
Sbjct: 396 IGGLSPFSEYAFRVLAVNSIGRGPPSEA--VRARTGEQAPSSPP 437
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEYYRT-----GWNVWLKAI 424
+ P PP+ V +V + W PPAD + Y V Y G +V + I
Sbjct: 624 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHV-VDGI 682
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ ++ L L + +EY+ ++A + G P ESSPV +
Sbjct: 683 SREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLV 721
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 76.6 bits (180), Expect = 5e-13
Identities = 87/337 (25%), Positives = 127/337 (37%), Gaps = 38/337 (11%)
Query: 167 SELSDVLTVSSDRASQEP---PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S D LT S+ R + P P+F + LEDV LE F SG P P + W
Sbjct: 63 STAKDELTCSA-RLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGC 121
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA------- 276
+ S + D L + DEG +A N G A A+L +E
Sbjct: 122 PMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASG 181
Query: 277 -APKLR----YPRQYEDGLLYEINETIFLKTT----------------IVGKPTPTIEWR 315
+ KL P + E G L ++ FL+ + G P PTI W
Sbjct: 182 PSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWF 241
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPP 374
H+GH I + D ++ L + G Y+ N +G+ A L P
Sbjct: 242 HNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVP 301
Query: 375 DPPRNV-SVTRQVDKSVTLDWEPPAD-DGGCKVGN--YIVEYYRTGWNVWLKAITS-RKT 429
PP V + VTL W PP D + Y V++ G + W +T R+
Sbjct: 302 GPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREP 361
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
L +G ++ FR+ + + S PS S PV++
Sbjct: 362 GWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQL 398
Score = 66.1 bits (154), Expect = 6e-10
Identities = 75/294 (25%), Positives = 110/294 (37%), Gaps = 19/294 (6%)
Query: 77 PAPP-GKPQIIPILSDDEPNAITLKWAPATHDGGA---PLRGYQVECNRLGSTEWIRTAP 132
P PP G PQ++ + +TL W P A Y V+ LGS +W TA
Sbjct: 301 PGPPDGAPQVVAVTG----RMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQW--TAL 354
Query: 133 PIVLR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD-VLTVSSDRASQEPPVFIKR 190
LR P TGL ++ FRV + S S S+ V + +E P + +
Sbjct: 355 VTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEAPAMLDK 414
Query: 191 LEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT---DESTSVLLFHQI 247
+ V +E VTF+ + + + W + +R D+ L ++
Sbjct: 415 PDIVYVVEGQPASVTVTFNHVEAQVV-WRSCRGALLEARAGVYELSQPDDDQYCLRICRV 473
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
D G + CTA NR H + LE A R+ ED + ET + GK
Sbjct: 474 SRRDMGALTCTARNR--HGTQTCSVTLELAEAPRFESIMED-VEVGAGETARFAVVVEGK 530
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
P P I W D + + L + S D G Y A+N+ GE
Sbjct: 531 PLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGE 584
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/95 (30%), Positives = 40/95 (42%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F +EDV + F V G P P I W+KD+ + S + +E+ L
Sbjct: 502 EAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSL 561
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G CTA N G KA L + +A
Sbjct: 562 VVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 596
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/165 (25%), Positives = 64/165 (38%), Gaps = 9/165 (5%)
Query: 308 PTPTIEWRHDGHPIITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W D + ++ + I S +L I A + G Y+ A N++G T++
Sbjct: 1630 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 1689
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW---LKA 423
V V P VT+ + + W+P C Y +E G +VW
Sbjct: 1690 TVAVARVPGKLAPPEVTQTYQDTALVLWKPGDSRAPC---TYTLERRVDGESVWHPVSSG 1746
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
I NVT L G +FR+ + G S+ S V + G
Sbjct: 1747 IPDCYYNVT--HLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRG 1789
Score = 39.9 bits (89), Expect = 0.048
Identities = 38/144 (26%), Positives = 58/144 (40%), Gaps = 6/144 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT-DEST 239
S PPVF +L+D LE + + P+P I+W KD + S I + +
Sbjct: 1599 SDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGR 1658
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP-KLRYPRQYEDGLLYEINETI 298
+L + G +C+ATN G + + + P KL P E Y+ +
Sbjct: 1659 QLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPP---EVTQTYQDTALV 1715
Query: 299 FLKTTIVGKP-TPTIEWRHDGHPI 321
K P T T+E R DG +
Sbjct: 1716 LWKPGDSRAPCTYTLERRVDGESV 1739
Score = 39.1 bits (87), Expect = 0.084
Identities = 31/132 (23%), Positives = 46/132 (34%), Gaps = 1/132 (0%)
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
LL + D G C + ARL + + + R ED + E F
Sbjct: 45 LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARF-D 103
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
I G P P + W H G P+ + + + L I D G Y + A N G+
Sbjct: 104 CKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQ 163
Query: 362 DTAAFLVTVTAP 373
+ + V P
Sbjct: 164 AHCSAQLYVEEP 175
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 76.2 bits (179), Expect = 6e-13
Identities = 70/256 (27%), Positives = 107/256 (41%), Gaps = 16/256 (6%)
Query: 209 SGIPSPTIAWFKDDYEIFSSR---RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
SG P P I WFKD + +S R ES L Q SD+G+ +C ATN G
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGT 209
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIIT 323
+ A L + PR +EI ++ + VG P P ++W +
Sbjct: 210 RYS-APANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLTP 268
Query: 324 DDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVT 383
+D + I +VL+++ ++S Y A + +G A +TV A P PP VT
Sbjct: 269 EDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVT 322
Query: 384 RQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDLIEGSEY 442
S+TL W+ + V YI+++ K I T ++ L S+Y
Sbjct: 323 ESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDY 379
Query: 443 KFRIKAESPYGMSAPS 458
+FR+ A + G PS
Sbjct: 380 EFRVVAVNNIGRGPPS 395
Score = 60.9 bits (141), Expect = 2e-08
Identities = 51/191 (26%), Positives = 81/191 (42%), Gaps = 13/191 (6%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRG 349
E T + G P P I W D P+ T + RI+ + L+I ++ SD+G
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQG 197
Query: 350 EYQIQAKNIIG 360
+Y+ A N G
Sbjct: 198 KYECVATNSAG 208
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 499 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 554
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 555 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 591
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 313 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 365
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 366 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 411
Score = 32.7 bits (71), Expect = 7.3
Identities = 30/133 (22%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 350 EYQIQAKNIIGEDTAAF-LVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKV 405
E+++ A N IG + ++T T AP PR+V ++ + W+ P + G ++
Sbjct: 380 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QI 438
Query: 406 GNYIVEYYRTGW---NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
Y V Y N W+K + T+ +L+ Y ++ A + G SS+
Sbjct: 439 QGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 498
Query: 463 PVR---IPGRAID 472
+ +PG+ ++
Sbjct: 499 VITQTGVPGQPLN 511
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 75.8 bits (178), Expect = 8e-13
Identities = 88/379 (23%), Positives = 147/379 (38%), Gaps = 33/379 (8%)
Query: 107 DGGAPLRGYQVECNRLGSTE----WIRTAPPIVLRPEL-VLTGLEPPHKYQFRVAALND- 160
D G+PLR EC G W++ P+ + + ++ G+ H A +
Sbjct: 402 DSGSPLRW---ECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQC 458
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWF 219
+ + Y + + + P + +L+ + D+ V G P PTI+W
Sbjct: 459 LAENKYGAI--YASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
K D + ++R AI D S +L SDEG+ C N G A A L ++ +
Sbjct: 517 KGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTR 573
Query: 280 LRY-PRQYEDGLLYEINETIFLKTTIVGKPT--PTIEWRHDGHPIITDDR----IEISIT 332
+ P++ E + E+I L + + T W G PI ++ I
Sbjct: 574 IELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQ 629
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
+ L I + G Y + + + + V PP PP V V + + TL
Sbjct: 630 ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATL 689
Query: 393 DWEPPADDGGCKVGNYIVEY---YRTGWNVWL---KAITSRKTNVTLFDLIEGSEYKFRI 446
W P AD+ + +Y ++ + GW + IT + DL EY+FR+
Sbjct: 690 SWSPAADNHS-PISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRV 748
Query: 447 KAESPYGMSAPSSESSPVR 465
A +P G PS+ S +R
Sbjct: 749 VATNPIGTGDPSTPSRMIR 767
Score = 70.5 bits (165), Expect = 3e-11
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P ++++L D + + +G P PT W K+ + R + VL+
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN----GVLMI 445
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
H + SD G +C A N+ G A L + A+ Q + ++ ++ + ++
Sbjct: 446 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 505
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G P PTI W+ + + R I+I P S L+I +A +SD G+Y + +N+ G
Sbjct: 506 QGSPKPTISWKKGDRAVRENKR--IAILPDGS-LRILNASKSDEGKYVCRGENVFGSAEI 562
Query: 365 AFLVTVTAP 373
++V P
Sbjct: 563 IASLSVKEP 571
Score = 61.3 bits (142), Expect = 2e-08
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 17/230 (7%)
Query: 173 LTVSSD--RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR 230
LT+ +D EP + + VTA + V+ G P PTI W K + I S R
Sbjct: 287 LTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKAR 346
Query: 231 TAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL 290
+S +VL + D G +C A N G + +L + P + + D
Sbjct: 347 LR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYP--HWVEKLNDTQ 400
Query: 291 LYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
L + + + GKP PT W +G P+ R+E+ VL IH+ +SD G
Sbjct: 401 L-DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGM 455
Query: 351 YQIQAKNIIGE--DTAAFLVTVTAPPDPPRNVSVTRQV--DKSVTLDWEP 396
YQ A+N G +A + +AP + T V D+ V ++ +P
Sbjct: 456 YQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 505
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 75.8 bits (178), Expect = 8e-13
Identities = 88/379 (23%), Positives = 147/379 (38%), Gaps = 33/379 (8%)
Query: 107 DGGAPLRGYQVECNRLGSTE----WIRTAPPIVLRPEL-VLTGLEPPHKYQFRVAALND- 160
D G+PLR EC G W++ P+ + + ++ G+ H A +
Sbjct: 108 DSGSPLRW---ECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQC 164
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWF 219
+ + Y + + + P + +L+ + D+ V G P PTI+W
Sbjct: 165 LAENKYGAI--YASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 222
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
K D + ++R AI D S +L SDEG+ C N G A A L ++ +
Sbjct: 223 KGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTR 279
Query: 280 LRY-PRQYEDGLLYEINETIFLKTTIVGKPT--PTIEWRHDGHPIITDDR----IEISIT 332
+ P++ E + E+I L + + T W G PI ++ I
Sbjct: 280 IELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQ 335
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
+ L I + G Y + + + + V PP PP V V + + TL
Sbjct: 336 ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATL 395
Query: 393 DWEPPADDGGCKVGNYIVEY---YRTGWNVWL---KAITSRKTNVTLFDLIEGSEYKFRI 446
W P AD+ + +Y ++ + GW + IT + DL EY+FR+
Sbjct: 396 SWSPAADNHS-PISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRV 454
Query: 447 KAESPYGMSAPSSESSPVR 465
A +P G PS+ S +R
Sbjct: 455 VATNPIGTGDPSTPSRMIR 473
Score = 70.5 bits (165), Expect = 3e-11
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P ++++L D + + +G P PT W K+ + R + VL+
Sbjct: 96 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN----GVLMI 151
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
H + SD G +C A N+ G A L + A+ Q + ++ ++ + ++
Sbjct: 152 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 211
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G P PTI W+ + + R I+I P S L+I +A +SD G+Y + +N+ G
Sbjct: 212 QGSPKPTISWKKGDRAVRENKR--IAILPDGS-LRILNASKSDEGKYVCRGENVFGSAEI 268
Query: 365 AFLVTVTAP 373
++V P
Sbjct: 269 IASLSVKEP 277
Score = 60.9 bits (141), Expect = 2e-08
Identities = 59/218 (27%), Positives = 91/218 (41%), Gaps = 15/218 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP + + VTA + V+ G P PTI W K + I S R +S +VL
Sbjct: 5 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR----KSQAVL 60
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ D G +C A N G + +L + P + + D L + + +
Sbjct: 61 EIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYP--HWVEKLNDTQL-DSGSPLRWEC 117
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE- 361
GKP PT W +G P+ R+E+ VL IH+ +SD G YQ A+N G
Sbjct: 118 KATGKPRPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGMYQCLAENKYGAI 173
Query: 362 -DTAAFLVTVTAPPDPPRNVSVTRQV--DKSVTLDWEP 396
+A + +AP + T V D+ V ++ +P
Sbjct: 174 YASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 211
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B
protein.
Length = 1960
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 5 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 64
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 65 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 121
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 122 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 181
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 182 SARASAELRIQSP 194
Score = 59.7 bits (138), Expect = 6e-08
Identities = 28/95 (29%), Positives = 42/95 (44%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D + PP +EDV A +F G P P++ W+KD ++ S R + +
Sbjct: 342 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 401
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+T L+ + D G C A N GG + KA L
Sbjct: 402 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 436
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 4/176 (2%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
+ +++ L + +P W DG P+ + R+ IS T K F +L I D G Y
Sbjct: 1468 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 1527
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N +G T ++ P + V L W+P G YIV+
Sbjct: 1528 CSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPV---TYIVQC 1584
Query: 413 YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
G + A L G Y FR S GM SS S V + G
Sbjct: 1585 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG 1640
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 97 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 156
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINET 297
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + +T
Sbjct: 157 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEDT 214
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLL 243
P F++ L D T + V S P+ W KD + SS R I+ T ++ +L
Sbjct: 1455 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 1514
Query: 244 FHQILPSDEGEIKCTATNRGGHAVT 268
++ D G C+ +N G T
Sbjct: 1515 ILVVVAEDLGVYTCSVSNALGTVTT 1539
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 745
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 746 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 805
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 806 SARASAELRIQSP 818
Score = 59.7 bits (138), Expect = 6e-08
Identities = 28/95 (29%), Positives = 42/95 (44%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D + PP +EDV A +F G P P++ W+KD ++ S R + +
Sbjct: 966 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+T L+ + D G C A N GG + KA L
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 4/176 (2%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
+ +++ L + +P W DG P+ + R+ IS T K F +L I D G Y
Sbjct: 2092 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 2151
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N +G T ++ P + V L W+P G YIV+
Sbjct: 2152 CSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPV---TYIVQC 2208
Query: 413 YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
G + A L G Y FR S GM SS S V + G
Sbjct: 2209 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG 2264
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINET 297
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + +T
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEDT 838
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLL 243
P F++ L D T + V S P+ W KD + SS R I+ T ++ +L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 244 FHQILPSDEGEIKCTATNRGGHAVT 268
++ D G C+ +N G T
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDESTSVLLFHQILPSDEGEI 255
+ F V G P PT+ W +++ E ++ T + + L+ + +G
Sbjct: 3 ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
C A+N G A+ A L + PK+ + ++ L+
Sbjct: 63 TCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 98
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 745
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 746 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 805
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 806 SARASAELRIQSP 818
Score = 59.7 bits (138), Expect = 6e-08
Identities = 28/95 (29%), Positives = 42/95 (44%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D + PP +EDV A +F G P P++ W+KD ++ S R + +
Sbjct: 966 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+T L+ + D G C A N GG + KA L
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 4/176 (2%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
+ +++ L + +P W DG P+ + R+ IS T K F +L I D G Y
Sbjct: 2092 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 2151
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N +G T ++ P + V L W+P G YIV+
Sbjct: 2152 CSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPV---TYIVQC 2208
Query: 413 YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
G + A L G Y FR S GM SS S V + G
Sbjct: 2209 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG 2264
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINET 297
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + +T
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEDT 838
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLL 243
P F++ L D T + V S P+ W KD + SS R I+ T ++ +L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 244 FHQILPSDEGEIKCTATNRGGHAVT 268
++ D G C+ +N G T
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDESTSVLLFHQILPSDEGEI 255
+ F V G P PT+ W +++ E ++ T + + L+ + +G
Sbjct: 3 ITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
C A+N G A+ A L + PK+ + ++ L+
Sbjct: 63 TCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 98
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 413 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 472
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 473 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 529
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 530 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 589
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 590 SARASAELRIQSP 602
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/135 (26%), Positives = 60/135 (44%), Gaps = 6/135 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 505 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 564
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINETI 298
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + T
Sbjct: 565 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEVT- 622
Query: 299 FLKTTIVGKPTPTIE 313
+ T V K T IE
Sbjct: 623 -EQETKVPKKTVIIE 636
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 75.8 bits (178), Expect = 8e-13
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 6/193 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVL 242
PP F + L D TA + V+ +G P P I+W+KD + I + + L
Sbjct: 629 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 688
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ + D G+ C A + G+ T ++ ++ P R+ + E + F
Sbjct: 689 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPP--RFVNKVRASPFVEGEDAQF-TC 745
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQIQAKNIIG 360
TI G P P I W DG + T ++ + P+ VL I +A + D G Y+ + N +G
Sbjct: 746 TIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLG 805
Query: 361 EDTAAFLVTVTAP 373
A+ + + +P
Sbjct: 806 SARASAELRIQSP 818
Score = 59.7 bits (138), Expect = 6e-08
Identities = 28/95 (29%), Positives = 42/95 (44%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE 237
D + PP +EDV A +F G P P++ W+KD ++ S R + +
Sbjct: 966 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 1025
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+T L+ + D G C A N GG + KA L
Sbjct: 1026 TTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAEL 1060
Score = 47.6 bits (108), Expect = 2e-04
Identities = 44/176 (25%), Positives = 62/176 (35%), Gaps = 4/176 (2%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
+ +++ L + +P W DG P+ + R+ IS T K F +L I D G Y
Sbjct: 2092 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 2151
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
N +G T ++ P + V L W+P G YIV+
Sbjct: 2152 CSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPV---TYIVQC 2208
Query: 413 YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
G + A L G Y FR S GM SS S V + G
Sbjct: 2209 SLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG 2264
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS- 240
Q PP F+ ++ +E + +F T G P P I W+KD + + + ++ +
Sbjct: 721 QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGL 780
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ-YEDGLLYEINET 297
VL+ D G +C NR G A A L ++ +P L+ Q + + L+ + +T
Sbjct: 781 LVLVIRAASKEDLGLYECELVNRLGSARASAELRIQ-SPMLQAQEQCHREQLVAAVEDT 838
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLL 243
P F++ L D T + V S P+ W KD + SS R I+ T ++ +L
Sbjct: 2079 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 2138
Query: 244 FHQILPSDEGEIKCTATNRGGHAVT 268
++ D G C+ +N G T
Sbjct: 2139 ILVVVAEDLGVYTCSVSNALGTVTT 2163
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDESTSVLLFHQILPSDEGEI 255
+ F V G P PT+ W +++ E ++ T + + L+ + +G
Sbjct: 3 ITFFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTY 62
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
C A+N G A+ A L + PK+ + ++ L+
Sbjct: 63 TCIASNAAGQALCSASLHVSGLPKVEEQEKVKEALI 98
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 75.8 bits (178), Expect = 8e-13
Identities = 88/379 (23%), Positives = 147/379 (38%), Gaps = 33/379 (8%)
Query: 107 DGGAPLRGYQVECNRLGSTE----WIRTAPPIVLRPEL-VLTGLEPPHKYQFRVAALND- 160
D G+PLR EC G W++ P+ + + ++ G+ H A +
Sbjct: 328 DSGSPLRW---ECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQC 384
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWF 219
+ + Y + + + P + +L+ + D+ V G P PTI+W
Sbjct: 385 LAENKYGAI--YASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 442
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
K D + ++R AI D S +L SDEG+ C N G A A L ++ +
Sbjct: 443 KGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTR 499
Query: 280 LRY-PRQYEDGLLYEINETIFLKTTIVGKPT--PTIEWRHDGHPIITDDR----IEISIT 332
+ P++ E + E+I L + + T W G PI ++ I
Sbjct: 500 IELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQ 555
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
+ L I + G Y + + + + V PP PP V V + + TL
Sbjct: 556 ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATL 615
Query: 393 DWEPPADDGGCKVGNYIVEY---YRTGWNVWL---KAITSRKTNVTLFDLIEGSEYKFRI 446
W P AD+ + +Y ++ + GW + IT + DL EY+FR+
Sbjct: 616 SWSPAADNHS-PISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRV 674
Query: 447 KAESPYGMSAPSSESSPVR 465
A +P G PS+ S +R
Sbjct: 675 VATNPIGTGDPSTPSRMIR 693
Score = 70.5 bits (165), Expect = 3e-11
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P ++++L D + + +G P PT W K+ + R + VL+
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN----GVLMI 371
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
H + SD G +C A N+ G A L + A+ Q + ++ ++ + ++
Sbjct: 372 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 431
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G P PTI W+ + + R I+I P S L+I +A +SD G+Y + +N+ G
Sbjct: 432 QGSPKPTISWKKGDRAVRENKR--IAILPDGS-LRILNASKSDEGKYVCRGENVFGSAEI 488
Query: 365 AFLVTVTAP 373
++V P
Sbjct: 489 IASLSVKEP 497
Score = 61.3 bits (142), Expect = 2e-08
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 17/230 (7%)
Query: 173 LTVSSD--RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR 230
LT+ +D EP + + VTA + V+ G P PTI W K + I S R
Sbjct: 213 LTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKAR 272
Query: 231 TAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL 290
+S +VL + D G +C A N G + +L + P + + D
Sbjct: 273 LR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYP--HWVEKLNDTQ 326
Query: 291 LYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
L + + + GKP PT W +G P+ R+E+ VL IH+ +SD G
Sbjct: 327 L-DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGM 381
Query: 351 YQIQAKNIIGE--DTAAFLVTVTAPPDPPRNVSVTRQV--DKSVTLDWEP 396
YQ A+N G +A + +AP + T V D+ V ++ +P
Sbjct: 382 YQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 431
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 75.8 bits (178), Expect = 8e-13
Identities = 88/379 (23%), Positives = 147/379 (38%), Gaps = 33/379 (8%)
Query: 107 DGGAPLRGYQVECNRLGSTE----WIRTAPPIVLRPEL-VLTGLEPPHKYQFRVAALND- 160
D G+PLR EC G W++ P+ + + ++ G+ H A +
Sbjct: 402 DSGSPLRW---ECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQC 458
Query: 161 VGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK-VEFHVTFSGIPSPTIAWF 219
+ + Y + + + P + +L+ + D+ V G P PTI+W
Sbjct: 459 LAENKYGAI--YASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
K D + ++R AI D S +L SDEG+ C N G A A L ++ +
Sbjct: 517 KGDRAVRENKRIAILPDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIASLSVKEPTR 573
Query: 280 LRY-PRQYEDGLLYEINETIFLKTTIVGKPT--PTIEWRHDGHPIITDDR----IEISIT 332
+ P++ E + E+I L + + T W G PI ++ I
Sbjct: 574 IELTPKRTE----LTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQ 629
Query: 333 PKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTL 392
+ L I + G Y + + + + V PP PP V V + + TL
Sbjct: 630 ASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATL 689
Query: 393 DWEPPADDGGCKVGNYIVEY---YRTGWNVWL---KAITSRKTNVTLFDLIEGSEYKFRI 446
W P AD+ + +Y ++ + GW + IT + DL EY+FR+
Sbjct: 690 SWSPAADNHS-PISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRV 748
Query: 447 KAESPYGMSAPSSESSPVR 465
A +P G PS+ S +R
Sbjct: 749 VATNPIGTGDPSTPSRMIR 767
Score = 70.5 bits (165), Expect = 3e-11
Identities = 46/189 (24%), Positives = 83/189 (43%), Gaps = 7/189 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P ++++L D + + +G P PT W K+ + R + VL+
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN----GVLMI 445
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
H + SD G +C A N+ G A L + A+ Q + ++ ++ + ++
Sbjct: 446 HNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 505
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G P PTI W+ + + R I+I P S L+I +A +SD G+Y + +N+ G
Sbjct: 506 QGSPKPTISWKKGDRAVRENKR--IAILPDGS-LRILNASKSDEGKYVCRGENVFGSAEI 562
Query: 365 AFLVTVTAP 373
++V P
Sbjct: 563 IASLSVKEP 571
Score = 61.3 bits (142), Expect = 2e-08
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 17/230 (7%)
Query: 173 LTVSSD--RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRR 230
LT+ +D EP + + VTA + V+ G P PTI W K + I S R
Sbjct: 287 LTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKAR 346
Query: 231 TAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGL 290
+S +VL + D G +C A N G + +L + P + + D
Sbjct: 347 LR----KSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYP--HWVEKLNDTQ 400
Query: 291 LYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
L + + + GKP PT W +G P+ R+E+ VL IH+ +SD G
Sbjct: 401 L-DSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM----VNGVLMIHNVNQSDAGM 455
Query: 351 YQIQAKNIIGE--DTAAFLVTVTAPPDPPRNVSVTRQV--DKSVTLDWEP 396
YQ A+N G +A + +AP + T V D+ V ++ +P
Sbjct: 456 YQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKP 505
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein.
Length = 1805
Score = 75.4 bits (177), Expect = 1e-12
Identities = 72/281 (25%), Positives = 117/281 (41%), Gaps = 10/281 (3%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS--RRTAITTDESTSVLLFHQILPS 250
D T ++ V SG P P I W K + + S + T ES S+L+ + S
Sbjct: 43 DSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHI-S 101
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
D G C ATN G A L + A ++ P Q + ++ ++ T + T
Sbjct: 102 DAGTYTCLATNSRGVDEASADLVVWARTRITKPPQ-DQSVIKGTQASMVCGVTHDPRVTI 160
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
W DG + T+ I + S L I D G Y + + G D+ + + V
Sbjct: 161 RYIWEKDGATLGTESHPRIRLDRNGS-LHISQTWSGDIGTYTCRVISAGGNDSRSAHLRV 219
Query: 371 TAPPDPPRN-VSVTRQVDK-SVTLDWEPPADDGGCKVGNYIVEYYRTG--WNVWLKAITS 426
P P + V+ V++ ++ L W P D G + YI+E W V L ++
Sbjct: 220 RQLPHAPEHPVATLSTVERRAINLTWTKPFD-GNSPLIRYILEMSENNAPWTVLLASVDP 278
Query: 427 RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
+ T+VT+ L+ Y+FR+ A + G S ++ V +P
Sbjct: 279 KATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLP 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW-IRTAPPI 134
RP PP +P + D ++ L W P + DG +P+R Y ++ L S W + +A
Sbjct: 1032 RPQPPSRPMVQQ--EDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVS 1088
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
++ L+P Y+FRV A ND+G S +SE S+ LT + P +
Sbjct: 1089 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 1140
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 3/118 (2%)
Query: 67 KNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE 126
++ H + P P P + LS E AI L W DG +PL Y +E + +
Sbjct: 213 RSAHLRVRQLPHAPEHP--VATLSTVERRAINLTWTKP-FDGNSPLIRYILEMSENNAPW 269
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP 184
+ A + + GL P YQFR+ A+NDVG +S+ ++ +++ + + P
Sbjct: 270 TVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPP 327
Score = 47.2 bits (107), Expect = 3e-04
Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 11/149 (7%)
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-----DTAAFLVTVTAPPDPPRNVSVTR 384
S+ PK + + + + ++++ A N +G+ DT + P PP+NV +
Sbjct: 275 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 334
Query: 385 QVDKSVTLDWEPPAD--DGGCKVGNYIVEYYRTGWNV--WLKAITSRK-TNVTLFDLIEG 439
+ ++S+ + W+PP + G G YI+ Y G V K IT N+ L DLI
Sbjct: 335 RTNQSIMIQWQPPPESHQNGILKG-YIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIW 393
Query: 440 SEYKFRIKAESPYGMSAPSSESSPVRIPG 468
+ Y+ + A + G+ SS+ + + G
Sbjct: 394 TNYEIEVAAYNSAGLGVYSSKVTEWTLQG 422
Score = 41.1 bits (92), Expect = 0.021
Identities = 41/150 (27%), Positives = 63/150 (42%), Gaps = 10/150 (6%)
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIV 305
++P D G +C A N G T L + + AP + R D + + ++ L
Sbjct: 3 LVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNI--TRGPLDSTVID-GMSVVLACETS 59
Query: 306 GKPTPTIEWRHDGHPIITDDRIEI-SITP-KFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P I W+ G I+ +++ TP + L I SD G Y A N G D
Sbjct: 60 GAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE 118
Query: 364 AAFLVTV---TAPPDPPRNVSVTRQVDKSV 390
A+ + V T PP++ SV + S+
Sbjct: 119 ASADLVVWARTRITKPPQDQSVIKGTQASM 148
Score = 41.1 bits (92), Expect = 0.021
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 338 LKIHSAKRSDRGEYQIQAKNII-GEDTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWE 395
LK+ ++I+AK G + A + T P P V + + ++ + W
Sbjct: 1419 LKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS 1478
Query: 396 PPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTNVTL-FDLIE-GSEYKFRIKAES 450
D G + Y++E + W++ +K I ++ T D+++ G Y FR+ A +
Sbjct: 1479 S-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1537
Query: 451 PYGMSAPSSESSPV 464
YG PSS S V
Sbjct: 1538 DYGFGTPSSPSQSV 1551
Score = 39.5 bits (88), Expect = 0.063
Identities = 39/120 (32%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP- 138
PG P I + + ++ L W P G L YQ+ +RL +T TA VL P
Sbjct: 934 PGPPMGI-LFPEVRTTSVRLIWQPPAAPNGIIL-AYQIT-HRLNTTT-ANTATVEVLAPS 989
Query: 139 --ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ TGL+P Y FR+ A G +E V T DR Q P + + EDV A
Sbjct: 990 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRA 1048
Score = 39.1 bits (87), Expect = 0.084
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 9/99 (9%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW---IRTA 131
G P PPG P I+ S AI + W+ G P+ Y +E W I+
Sbjct: 1456 GAPGPPGVPIIVRYSS-----AIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1509
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
P V + L+P Y FRV A+ND G S S
Sbjct: 1510 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 1548
Score = 37.5 bits (83), Expect = 0.26
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 360 GEDTAAFLVTVTAP--PDPPRNVSVTRQV--DKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
GE A +VT P PP V ++ +SV L WEP DG V Y ++
Sbjct: 1017 GEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTREL 1075
Query: 416 GWNVWLKAITSRKTNVTLF--DLIEG-SEYKFRIKAESPYGMSAPSSES 461
W S N + F D ++ + YKFR+KA + G S S ES
Sbjct: 1076 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1124
Score = 36.7 bits (81), Expect = 0.45
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
Query: 350 EYQIQAKNIIGE----DTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWEPPADD 400
+++++A N IG+ + + L T+ A PD P +SVT SV + W+PPA+D
Sbjct: 1106 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAED 1161
Score = 35.1 bits (77), Expect = 1.4
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SR 427
T A P P +V + SV + WE P G G +V + + K +T
Sbjct: 1352 TQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDV 1411
Query: 428 KTNVTLF----DLIEGSEYKFRIKAES-PYGMSAPSSESSPVRIPG 468
K N L+ DL EG Y+FRI+A++ YG P E++ PG
Sbjct: 1412 KGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG---PEIEANVTTGPG 1454
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 72.9 bits (171), Expect = 6e-12
Identities = 59/208 (28%), Positives = 79/208 (37%), Gaps = 8/208 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS-RRTAITTDESTSVLL 243
PVF+ + LE F + G P P WF D +I + + ++ T L+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
PSD GE A NR G + L +EA P E I E + +K
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMK 1576
Query: 302 TTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
G P P I W + I+ +I I T + LKI S D Y A N
Sbjct: 1577 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636
Query: 360 GEDTAAFLVTVT---APPDPPRNVSVTR 384
G DT V V A P+P R + + R
Sbjct: 1637 GRDTTRCKVNVEVEFAEPEPERKLIIPR 1664
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/94 (31%), Positives = 47/94 (50%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + L++VT +E + V SG PSPT+ W+++DY+I SS IT + L+
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G C+A N G T L ++ +
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/201 (23%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 3356 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 353 IQAKNIIGEDTAAFLVTVTAP 373
A N +G+ ++ +++ AP
Sbjct: 3416 FVASNAVGQVSSTANLSLEAP 3436
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/91 (35%), Positives = 42/91 (46%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP FIK + D A F G P PT+ W+KD + R T + L
Sbjct: 5513 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLF 5572
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ SDEGE +C ATN+ G A + A L L
Sbjct: 5573 ITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/101 (28%), Positives = 47/101 (46%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + PP F++ +E E D F F G P P + W+ +D I ++ I + E+
Sbjct: 3938 RPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN 3997
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
S+L + +EG I C N+ G T + L ++A K
Sbjct: 3998 YSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK 4038
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/196 (26%), Positives = 81/196 (41%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF + EI S + + +
Sbjct: 2786 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVS 2844
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 2845 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 2896
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 2897 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 2953
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 2954 --VCGNDQVSATLTVT 2967
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA-ITTDEST 239
S E P +R++ T + F V G P P W+K+ +I S R +++
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ + D I A N G + A L ++A + + ++ +D + E +T+
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE-KDTMA 2192
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+P ++W DG + D+ + K L I + SD +Y
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2244
Score = 54.4 bits (125), Expect = 2e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFH 245
F R+++ LE V FH SG P P IAW+KD I R + + + L
Sbjct: 1293 FDLRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+LP DEG A+N G+A+ +L +E A L P
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 3024
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 3025 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 3077
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 3131
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L++ P ++ V A N G S+ +S +LTV + Q P+F+++L++V E
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSS---ISVILTVEAVE-HQVKPMFVEKLKNVNIKEG 1570
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVLLFHQILPSDEGEIKC 257
++E V +G P+P I W K+ I + + I + + L + D
Sbjct: 1571 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1630
Query: 258 TATNRGGHAVTKARLCLE 275
TA N+ G T+ ++ +E
Sbjct: 1631 TAINKAGRDTTRCKVNVE 1648
Score = 49.6 bits (113), Expect = 6e-05
Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 3356 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3414
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPR 284
A+N G + A L LEA + + R
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHER 3443
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP FI + D EN F + GIP+P + W+K+ I + I+ ++ + L
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTL 5438
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ SD +C A N G A+ + L +
Sbjct: 5439 KIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 5470
Score = 44.0 bits (99), Expect = 0.003
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPS 213
+ DV + E S V+ T + P ++ L D E D V+ V S + S
Sbjct: 2325 VKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LES 2383
Query: 214 PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC 273
W KD E+ S R I D+ + +LL + D G T G T R+
Sbjct: 2384 VEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALG--LSTSGRVS 2441
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+ + + +D + E + + L+ + +++W + I DDR++ +
Sbjct: 2442 VYSVDVI---TPLKDVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497
Query: 334 KFSVLKIHSAKRSDRGEYQI 353
L I+ SD G Y++
Sbjct: 2498 TKQRLVINRTHASDEGPYKL 2517
Score = 43.6 bits (98), Expect = 0.004
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 6/146 (4%)
Query: 169 LSDVLTVSSDRASQEP--PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF 226
++D EP P FI + +E V F G P P + W K +
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 227 SSRRTAITTDESTS--VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ R ++ ++ T L+ D GE N+ G A L EA +L
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTP 310
Q E +LY+ T F++ VG+ P
Sbjct: 1184 QQE--MLYQTQVTAFVQEPKVGETAP 1207
Score = 43.6 bits (98), Expect = 0.004
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 291 LYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
+YE N T+ + G P P ++W + + D+RI++ L+I + ++ + GE
Sbjct: 5194 VYE-NTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGE 5252
Query: 351 YQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
Y A NIIGE A V P R V++ V ++++
Sbjct: 5253 YMCHAVNIIGE--AKSFANVDIMPQEERVVALPPPVTHQHVMEFD 5295
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 175 VSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
V++D+ ++ P + E V LE + F +G P P + W+ + I S+R +
Sbjct: 1831 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1890
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
D L D GE+K TA N G K +L ++ R
Sbjct: 1891 YD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFR 1936
Score = 41.9 bits (94), Expect = 0.012
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 181 SQEPPVFIKRL-EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+ EPP ++ + + E D + SG P P + WF++ + +++ +
Sbjct: 4154 TNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCS 4213
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLY 292
L + D G+ KC A N G + + L +E R Q+E+ G +Y
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPV-TYRENSQFENIGEIY 4266
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L+DV A E D + + P + W+KD E+ + + +D L
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2235
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
I SD + C + T A+L +E A + + ++ +D E+ E+ + +
Sbjct: 2236 IDTSDAEDYSCVLV-EDENVKTTAKLIVEGA-VVEFVKELQD---IEVPESYSGELECIV 2290
Query: 307 KPTPTIE--WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
P IE W H+ + ++ + I+ L + + D+GEY
Sbjct: 2291 SP-ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 41.1 bits (92), Expect = 0.021
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 2529 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 2587
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 2588 KLTVLNMMKDDEGKY----TFYAGENITSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 2639
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 2640 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 2696
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 2697 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2756
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 2757 VKG-TIYSLRIKNCAIVDESVYGFRL 2781
Score = 39.1 bits (87), Expect = 0.084
Identities = 24/92 (26%), Positives = 39/92 (42%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP FI+ L EN + F V G+P P + W+++ + R + +
Sbjct: 5179 NEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVC 5238
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L I + GE C A N G A + A +
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270
Score = 38.3 bits (85), Expect = 0.15
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 2/114 (1%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT--IAWFKDDYEIFSSRRTAITT 235
D+ Q+ P F K+L + F + I PT + W D + ++ R +
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN 1755
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ L + D G I C ATN+ G T A L ++ L Q +G
Sbjct: 1756 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEG 1809
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ T +G PT +EW HDG P+ +R+ + + L A D G +A N G
Sbjct: 1725 RLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1784
Query: 361 ED-TAAFLV 368
D T+A L+
Sbjct: 1785 TDHTSATLI 1793
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQ 352
N K +++G PTP ++W + + I D I+ I+ + LKI + SD Y+
Sbjct: 5394 NSDAVFKCSVIGIPTPEVKW-YKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYR 5452
Query: 353 IQAKNIIGE 361
+A N +GE
Sbjct: 5453 CRAVNCVGE 5461
Score = 36.3 bits (80), Expect = 0.59
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK--IHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P+ T R ++S + K I D GEY I +N GE +
Sbjct: 1107 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1166
Query: 364 AA 365
A+
Sbjct: 1167 AS 1168
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E++ L+ I G P+PT+ W + + I + +I+ + L I A D G + A
Sbjct: 958 ESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 1017
Query: 356 KNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQ 385
N G T+ +L + +VT +
Sbjct: 1018 VNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Score = 35.5 bits (78), Expect = 1.0
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 160 DVGHSNYSELSDVLTVSSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
D+ H + + +SS + E P F ++L LE + V F P+P +
Sbjct: 3477 DIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMT 3536
Query: 218 WFKDDYEIFSSRRTAITTDES----TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
WF ++ I + R I + +S L ++ D G + A N G A + A L
Sbjct: 3537 WFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595
Score = 35.1 bits (77), Expect = 1.4
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDR----IEISITPKFSVLKIHSAKRSDRGEY 351
E + ++ PTP + W H+ PI T R E + S L+I + D G Y
Sbjct: 3519 EPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSY 3578
Query: 352 QIQAKNIIG--EDTAAFLV 368
++ A N G E TA+ LV
Sbjct: 3579 RLLAINSEGSAESTASLLV 3597
Score = 34.7 bits (76), Expect = 1.8
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
I + + + G P PT+ W DG ++ R + + F L I S +SD GEY+
Sbjct: 5527 IGTAAYFQCLVRGSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYR 5585
Query: 353 IQAKNIIG--EDTAAFLVT 369
A N G E AA +T
Sbjct: 5586 CVATNKSGMAESFAALTLT 5604
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 75.4 bits (177), Expect = 1e-12
Identities = 51/203 (25%), Positives = 82/203 (40%), Gaps = 2/203 (0%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTS 240
+ P F + L+ V LE F SG P P ++WF+D I +S I+ + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L + ++ G ATN G A + A L ++A Q + + L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ + G PTP +++ DG I + +IS L I A D G Y + A N +G
Sbjct: 124 QVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Query: 361 EDTAAFLVTVTAPPDPPRNVSVT 383
T+ + V + P + T
Sbjct: 184 RATSTAELLVQGEEEVPAKKTKT 206
Score = 72.9 bits (171), Expect = 6e-12
Identities = 59/208 (28%), Positives = 79/208 (37%), Gaps = 8/208 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS-RRTAITTDESTSVLL 243
PVF+ + LE F + G P P WF D +I + + ++ T L+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
PSD GE A NR G + L +EA P E I E + +K
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMK 1576
Query: 302 TTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
G P P I W + I+ +I I T + LKI S D Y A N
Sbjct: 1577 VRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKA 1636
Query: 360 GEDTAAFLVTVT---APPDPPRNVSVTR 384
G DT V V A P+P R + + R
Sbjct: 1637 GRDTTRCKVNVEVEFAEPEPERKLIIPR 1664
Score = 69.3 bits (162), Expect = 7e-11
Identities = 30/94 (31%), Positives = 47/94 (50%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP + L++VT +E + V SG PSPT+ W+++DY+I SS IT + L+
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
+ D G C+A N G T L ++ +
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVS 1035
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/97 (31%), Positives = 50/97 (51%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
+A PP F++RL+ +T + +V V +GIP+P + +++D EI SS I+ +
Sbjct: 98 KAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGD 157
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
LL + P D G ATN G A + A L ++
Sbjct: 158 LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/201 (23%), Positives = 78/201 (38%), Gaps = 11/201 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 3356 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 353 IQAKNIIGEDTAAFLVTVTAP 373
A N +G+ ++ +++ AP
Sbjct: 3416 FVASNAVGQVSSTANLSLEAP 3436
Score = 57.6 bits (133), Expect = 2e-07
Identities = 32/91 (35%), Positives = 42/91 (46%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
PP FIK + D A F G P PT+ W+KD + R T + L
Sbjct: 5513 PPRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLF 5572
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
++ SDEGE +C ATN+ G A + A L L
Sbjct: 5573 ITSLVKSDEGEYRCVATNKSGMAESFAALTL 5603
Score = 56.4 bits (130), Expect = 5e-07
Identities = 29/101 (28%), Positives = 47/101 (46%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + PP F++ +E E D F F G P P + W+ +D I ++ I + E+
Sbjct: 3938 RPQRCPPSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN 3997
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
S+L + +EG I C N+ G T + L ++A K
Sbjct: 3998 YSILTLSSVHHQNEGSITCVLFNQYGTVKTTSMLKVKAKQK 4038
Score = 55.2 bits (127), Expect = 1e-06
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 1/98 (1%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFH 245
F R+++ LE V FH SG P P IAW+KD I R + + + L
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 246 QILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+LP DEG A+N G+A+ +L +E A L P
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 55.2 bits (127), Expect = 1e-06
Identities = 38/172 (22%), Positives = 69/172 (40%), Gaps = 2/172 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA-ITTDEST 239
S E P +R++ T + F V G P P W+K+ +I S R +++
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ + D I A N G + A L ++A + + ++ +D + E +T+
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKE-KDTMA 2192
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
+P ++W DG + D+ + K L I + SD +Y
Sbjct: 2193 TFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDY 2244
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF EI S + + +
Sbjct: 2786 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVS 2844
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 2845 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 2896
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 2897 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 2953
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 2954 --VCGNDQVSATLTVT 2967
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 2968 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 3024
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 3025 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 3077
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 3078 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 3131
Score = 52.4 bits (120), Expect = 8e-06
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L++ P ++ V A N G S+ +S +LTV + Q P+F+++L++V E
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRSS---ISVILTVEAVE-HQVKPMFVEKLKNVNIKEG 1570
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVLLFHQILPSDEGEIKC 257
++E V +G P+P I W K+ I + + I + + L + D
Sbjct: 1571 SRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1630
Query: 258 TATNRGGHAVTKARLCLE 275
TA N+ G T+ ++ +E
Sbjct: 1631 TAINKAGRDTTRCKVNVE 1648
Score = 49.6 bits (113), Expect = 6e-05
Identities = 42/149 (28%), Positives = 56/149 (37%), Gaps = 5/149 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 3296 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 3355
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 3356 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 3414
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPR 284
A+N G + A L LEA + + R
Sbjct: 3415 TFVASNAVGQVSSTANLSLEAPESILHER 3443
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP FI + D EN F + GIP+P + W+K+ I + I+ ++ + L
Sbjct: 5379 PPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTL 5438
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCL 274
+ SD +C A N G A+ + L +
Sbjct: 5439 KIRNVCLSDSATYRCRAVNCVGEAICRGFLTM 5470
Score = 44.0 bits (99), Expect = 0.003
Identities = 45/200 (22%), Positives = 78/200 (39%), Gaps = 11/200 (5%)
Query: 158 LNDVGHSNYSELSDVL----TVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPS 213
+ DV + E S V+ T + P ++ L D E D V+ V S + S
Sbjct: 2325 VKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LES 2383
Query: 214 PTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLC 273
W KD E+ S R I D+ + +LL + D G T G T R+
Sbjct: 2384 VEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALG--LSTSGRVS 2441
Query: 274 LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP 333
+ + + +D + E + + L+ + +++W + I DDR++ +
Sbjct: 2442 VYSVDVI---TPLKDVNVIEGTKAV-LECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKG 2497
Query: 334 KFSVLKIHSAKRSDRGEYQI 353
L I+ SD G Y++
Sbjct: 2498 TKQRLVINRTHASDEGPYKL 2517
Score = 43.6 bits (98), Expect = 0.004
Identities = 36/146 (24%), Positives = 55/146 (37%), Gaps = 6/146 (4%)
Query: 169 LSDVLTVSSDRASQEP--PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF 226
++D EP P FI + +E V F G P P + W K +
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLT 1123
Query: 227 SSRRTAITTDESTS--VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ R ++ ++ T L+ D GE N+ G A L EA +L
Sbjct: 1124 TGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKS 1183
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTP 310
Q E +LY+ T F++ VG+ P
Sbjct: 1184 QQE--MLYQTQVTAFVQEPKVGETAP 1207
Score = 43.6 bits (98), Expect = 0.004
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 291 LYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGE 350
+YE N T+ + G P P ++W + + D+RI++ L+I + ++ + GE
Sbjct: 5194 VYE-NTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGE 5252
Query: 351 YQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE 395
Y A NIIGE A V P R V++ V ++++
Sbjct: 5253 YMCHAVNIIGE--AKSFANVDIMPQEERVVALPPPVTHQHVMEFD 5295
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/107 (26%), Positives = 45/107 (42%), Gaps = 1/107 (0%)
Query: 175 VSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT 234
V++D+ ++ P + E V LE + F +G P P + W+ + I S+R +
Sbjct: 1831 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1890
Query: 235 TDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLR 281
D L D GE+K TA N G K +L ++ R
Sbjct: 1891 YD-GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFR 1936
Score = 41.9 bits (94), Expect = 0.012
Identities = 26/114 (22%), Positives = 48/114 (42%), Gaps = 3/114 (2%)
Query: 181 SQEPPVFIKRL-EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
+ EPP ++ + + E D + SG P P + WF++ + +++ +
Sbjct: 4154 TNEPPKMLQEMPKHARCREGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCS 4213
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED-GLLY 292
L + D G+ KC A N G + + L +E R Q+E+ G +Y
Sbjct: 4214 HQLYIKDVNSQDSGKYKCVAENNSGAVESVSDLTVEPV-TYRENSQFENIGEIY 4266
Score = 41.5 bits (93), Expect = 0.016
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + L+DV A E D + + P + W+KD E+ + + +D L
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2235
Query: 247 ILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVG 306
I SD + C + T A+L +E A + + ++ +D E+ E+ + +
Sbjct: 2236 IDTSDAEDYSCVLV-EDENVKTTAKLIVEGA-VVEFVKELQD---IEVPESYSGELECIV 2290
Query: 307 KPTPTIE--WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
P IE W H+ + ++ + I+ L + + D+GEY
Sbjct: 2291 SP-ENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEY 2336
Score = 40.3 bits (90), Expect = 0.036
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 2529 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 2587
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 2588 KLTVLNMMKDDEGKY----TFYAGENMTSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 2639
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 2640 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 2696
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 2697 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 2756
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 2757 VKG-TIYSLRIKNCAIVDESVYGFRL 2781
Score = 39.1 bits (87), Expect = 0.084
Identities = 24/92 (26%), Positives = 39/92 (42%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP FI+ L EN + F V G+P P + W+++ + R + +
Sbjct: 5179 NEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVC 5238
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L I + GE C A N G A + A +
Sbjct: 5239 SLEISNIQKGEGGEYMCHAVNIIGEAKSFANV 5270
Score = 38.3 bits (85), Expect = 0.15
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 2/114 (1%)
Query: 178 DRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPT--IAWFKDDYEIFSSRRTAITT 235
D+ Q+ P F K+L + F + I PT + W D + ++ R +
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMIN 1755
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDG 289
+ L + D G I C ATN+ G T A L ++ L Q +G
Sbjct: 1756 EFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEG 1809
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+ T +G PT +EW HDG P+ +R+ + + L A D G +A N G
Sbjct: 1725 RLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYG 1784
Query: 361 ED-TAAFLV 368
D T+A L+
Sbjct: 1785 TDHTSATLI 1793
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK--FSVLKIHSAKRSDRGEYQ 352
N K +++G PTP ++W + + I D I+ I+ + LKI + SD Y+
Sbjct: 5394 NSDAVFKCSVIGIPTPEVKW-YKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYR 5452
Query: 353 IQAKNIIGE 361
+A N +GE
Sbjct: 5453 CRAVNCVGE 5461
Score = 36.3 bits (80), Expect = 0.59
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLK--IHSAKRSDRGEYQIQAKNIIGEDT 363
G P P + W+ G P+ T R ++S + K I D GEY I +N GE +
Sbjct: 1107 GNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETS 1166
Query: 364 AA 365
A+
Sbjct: 1167 AS 1168
Score = 35.9 bits (79), Expect = 0.78
Identities = 22/91 (24%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
E++ L+ I G P+PT+ W + + I + +I+ + L I A D G + A
Sbjct: 958 ESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSA 1017
Query: 356 KNIIGE-DTAAFLVTVTAPPDPPRNVSVTRQ 385
N G T+ +L + +VT +
Sbjct: 1018 VNEAGTVSTSCYLAVQVSEEFEKETTAVTEK 1048
Score = 35.5 bits (78), Expect = 1.0
Identities = 29/119 (24%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 160 DVGHSNYSELSDVLTVSSDRASQE--PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIA 217
D+ H + + +SS + E P F ++L LE + V F P+P +
Sbjct: 3477 DIDHKSMAAKRYASRISSTSSWPEYFKPSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMT 3536
Query: 218 WFKDDYEIFSSRRTAITTDES----TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
WF ++ I + R I + +S L ++ D G + A N G A + A L
Sbjct: 3537 WFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSYRLLAINSEGSAESTASL 3595
Score = 35.1 bits (77), Expect = 1.4
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDR----IEISITPKFSVLKIHSAKRSDRGEY 351
E + ++ PTP + W H+ PI T R E + S L+I + D G Y
Sbjct: 3519 EPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSGSY 3578
Query: 352 QIQAKNIIG--EDTAAFLV 368
++ A N G E TA+ LV
Sbjct: 3579 RLLAINSEGSAESTASLLV 3597
Score = 34.7 bits (76), Expect = 1.8
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 4/79 (5%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK-FSVLKIHSAKRSDRGEYQ 352
I + + + G P PT+ W DG ++ R + + F L I S +SD GEY+
Sbjct: 5527 IGTAAYFQCLVRGSPRPTVYWYKDGK-LVQGRRFTVEESGTGFHNLFITSLVKSDEGEYR 5585
Query: 353 IQAKNIIG--EDTAAFLVT 369
A N G E AA +T
Sbjct: 5586 CVATNKSGMAESFAALTLT 5604
>AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 812
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 485 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 544
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 545 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 604
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 605 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 661
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 662 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 720
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 721 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 779
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 780 IHPSSTYSIRMYAKNRIGKSEPSNE 804
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
SD A+ P + + + A+ +VE G P P W KD+ + S R
Sbjct: 48 SDPANSAPSI-LDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRF----Q 102
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEIN 295
++ + LL I PSD G C +NR G A RL ++ K PR+ + +
Sbjct: 103 KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS----SVG 158
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ L ++ G + W +G + + I+ +++ H K SD G YQ
Sbjct: 159 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVK-SDGGAYQ 214
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 328 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 384
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 385 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 441
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 442 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 501
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 502 RNEAAAVEHQSQLIVRVPP 520
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 448 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 507
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 508 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 564
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 565 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 617
Score = 48.8 bits (111), Expect = 1e-04
Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 10/105 (9%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 715 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 770
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRA 180
+L + + P Y R+ A N +G SE S+ LT+++D A
Sbjct: 771 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEA 812
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 160 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 218
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 219 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 275
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 276 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 335
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 336 SIRPMKNIT 344
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 237 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 296
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 297 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 352
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 353 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 411
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 412 QLSTSQSVHVTVKVPP 427
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell
adhesion molecule splice variant protein.
Length = 1746
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 407 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 466
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 467 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 526
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 527 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 583
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 584 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 642
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 643 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 701
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 702 IHPSSTYSIRMYAKNRIGKSEPSNE 726
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 1055 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 1113
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 1114 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 1171
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 1172 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1210
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 637 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 692
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+L + + P Y R+ A N +G SE S+ LT+++D A+ + P LE ++
Sbjct: 693 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPIS 749
Query: 196 A 196
+
Sbjct: 750 S 750
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 250 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 306
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 307 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 363
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 364 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 423
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 424 RNEAAAVEHQSQLIVRVPP 442
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 370 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 429
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 430 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 486
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 487 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 539
Score = 46.8 bits (106), Expect = 4e-04
Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 10/144 (6%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P W KD+ + S R ++ + LL I PSD G C +NR G A
Sbjct: 2 GHPEPDYRWLKDNMPLELSGRF----QKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVI 57
Query: 270 ARLCLEAAPKLRY-PRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
RL ++ K PR+ + + + L ++ G + W +G + +
Sbjct: 58 GRLYVKQPLKATISPRKVKS----SVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVR 113
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQ 352
I+ +++ H K SD G YQ
Sbjct: 114 ITGINHENLIMDHMVK-SDGGAYQ 136
Score = 46.0 bits (104), Expect = 7e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 1131 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 1186
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 1187 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 1240
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+V ++ I F +Y F + T TT + TS+
Sbjct: 1241 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSL 1281
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 82 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 140
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 141 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 197
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 198 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 257
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 258 SIRPMKNIT 266
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 159 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 218
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 219 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 274
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 275 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 333
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 334 QLSTSQSVHVTVKVPP 349
Score = 41.1 bits (92), Expect = 0.021
Identities = 72/365 (19%), Positives = 136/365 (37%), Gaps = 34/365 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 1000 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 1054
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 1055 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1110
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 1111 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 1161
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 1162 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1221
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 1222 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 1281
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEAL 487
+ L+DL E + Y+ +++ + G + + + + G I +V E L
Sbjct: 1282 SKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQN--EEGL 1339
Query: 488 TREDG 492
T +G
Sbjct: 1340 TTNEG 1344
Score = 39.5 bits (88), Expect = 0.063
Identities = 77/300 (25%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 185 PVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDE-STSV 241
P I + T A + K E T G + W K+D I R ++T E V
Sbjct: 539 PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEV 598
Query: 242 LLFHQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ET 297
+ QILP+ D G C A N G +L ++ P P + E + ++ T
Sbjct: 599 ISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD---PPEIE---IKDVKART 652
Query: 298 IFLKTTIV--GKPTPT---IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L+ T+ G T IE ++ + R + ++P+ + I S +
Sbjct: 653 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTK-DVSPQLNSATIIDIHPSSTYSIR 711
Query: 353 IQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPPAD--DGGCKVG 406
+ AKN IG+ + +T+TA P PP+ V + +S+ + W+ P G +
Sbjct: 712 MYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI-IR 770
Query: 407 NYIVEY--YRTGWNVWLKAI---TSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
Y + Y Y TG N I TS + V TL +L + ++Y ++A + G + PSS+
Sbjct: 771 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGPSSQ 829
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 106 HDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSN 165
+DGG P+ + +E G+T W TA L +L L+ Y+ ++ N G +
Sbjct: 1252 NDGGCPITSFTLEYRPFGTTVW-TTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCA- 1309
Query: 166 YSELSDVLTVSSDRASQEPPVFIKRLEDVTAL-ENDKVEFHVTFSGI 211
+ ++ T++ D S PP+ +++ L N+ ++ VT S I
Sbjct: 1310 -EKQANFATLNYD-GSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCI 1354
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 2012
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 655 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 714
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 715 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 774
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 775 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 831
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 832 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 890
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 891 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 949
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 950 IHPSSTYSIRMYAKNRIGKSEPSNE 974
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 1361
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 1362 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 1419
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 1420 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 885 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 940
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+L + + P Y R+ A N +G SE S+ LT+++D A+ + P LE ++
Sbjct: 941 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPIS 997
Query: 196 A 196
+
Sbjct: 998 S 998
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
SD A+ P + + + A+ +VE G P P W KD+ + S R
Sbjct: 218 SDPANSAPSI-LDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRF----Q 272
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEIN 295
++ + LL I PSD G C +NR G A RL ++ K PR+ + +
Sbjct: 273 KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS----SVG 328
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ L ++ G + W +G + + I+ +++ H K SD G YQ
Sbjct: 329 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVK-SDGGAYQ 384
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 498 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 554
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 555 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 611
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 612 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 671
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 672 RNEAAAVEHQSQLIVRVPP 690
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 618 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 677
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 678 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 734
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 735 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 787
Score = 46.0 bits (104), Expect = 7e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 1379 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 1434
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 1435 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 1488
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+V ++ I F +Y F + T TT + TS+
Sbjct: 1489 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSL 1529
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 330 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 388
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 389 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 445
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 446 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 505
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 506 SIRPMKNIT 514
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 522
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 523 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 581
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 582 QLSTSQSVHVTVKVPP 597
Score = 41.1 bits (92), Expect = 0.021
Identities = 72/365 (19%), Positives = 136/365 (37%), Gaps = 34/365 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 1248 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 1302
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1358
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 1359 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 1409
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 1410 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1469
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 1470 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 1529
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEAL 487
+ L+DL E + Y+ +++ + G + + + + G I +V E L
Sbjct: 1530 SKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQN--EEGL 1587
Query: 488 TREDG 492
T +G
Sbjct: 1588 TTNEG 1592
Score = 39.5 bits (88), Expect = 0.063
Identities = 77/300 (25%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 185 PVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDE-STSV 241
P I + T A + K E T G + W K+D I R ++T E V
Sbjct: 787 PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEV 846
Query: 242 LLFHQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ET 297
+ QILP+ D G C A N G +L ++ P P + E + ++ T
Sbjct: 847 ISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD---PPEIE---IKDVKART 900
Query: 298 IFLKTTIV--GKPTPT---IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L+ T+ G T IE ++ + R + ++P+ + I S +
Sbjct: 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTK-DVSPQLNSATIIDIHPSSTYSIR 959
Query: 353 IQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPPAD--DGGCKVG 406
+ AKN IG+ + +T+TA P PP+ V + +S+ + W+ P G +
Sbjct: 960 MYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI-IR 1018
Query: 407 NYIVEY--YRTGWNVWLKAI---TSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
Y + Y Y TG N I TS + V TL +L + ++Y ++A + G + PSS+
Sbjct: 1019 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGPSSQ 1077
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 106 HDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSN 165
+DGG P+ + +E G+T W TA L +L L+ Y+ ++ N G +
Sbjct: 1500 NDGGCPITSFTLEYRPFGTTVW-TTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCA- 1557
Query: 166 YSELSDVLTVSSDRASQEPPVFIKRLEDVTAL-ENDKVEFHVTFSGI 211
+ ++ T++ D S PP+ +++ L N+ ++ VT S I
Sbjct: 1558 -EKQANFATLNYD-GSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCI 1602
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1571
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 655 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 714
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 715 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 774
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 775 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 831
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 832 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 890
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 891 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 949
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 950 IHPSSTYSIRMYAKNRIGKSEPSNE 974
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 1361
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 1362 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 1419
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 1420 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 885 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 940
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+L + + P Y R+ A N +G SE S+ LT+++D A+ + P LE ++
Sbjct: 941 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPIS 997
Query: 196 A 196
+
Sbjct: 998 S 998
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
SD A+ P + + + A+ +VE G P P W KD+ + S R
Sbjct: 218 SDPANSAPSI-LDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRF----Q 272
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEIN 295
++ + LL I PSD G C +NR G A RL ++ K PR+ + +
Sbjct: 273 KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS----SVG 328
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ L ++ G + W +G + + I+ +++ H K SD G YQ
Sbjct: 329 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVK-SDGGAYQ 384
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 498 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 554
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 555 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 611
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 612 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 671
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 672 RNEAAAVEHQSQLIVRVPP 690
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 618 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 677
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 678 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 734
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 735 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 787
Score = 46.8 bits (106), Expect = 4e-04
Identities = 47/196 (23%), Positives = 85/196 (43%), Gaps = 15/196 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 1379 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 1434
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 1435 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 1488
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV---LLFHQILPSDEGEI 255
+V ++ I F +Y F + T TT + TS+ + + + + E+
Sbjct: 1489 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSLSKSYILYDLQEATWYEL 1546
Query: 256 KCTATNRGGHAVTKAR 271
+ N G A +A+
Sbjct: 1547 QMRVCNSAGCAEKQAK 1562
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 330 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 388
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 389 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 445
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 446 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 505
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 506 SIRPMKNIT 514
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 467 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 522
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 523 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 581
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 582 QLSTSQSVHVTVKVPP 597
Score = 39.5 bits (88), Expect = 0.063
Identities = 77/300 (25%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 185 PVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDE-STSV 241
P I + T A + K E T G + W K+D I R ++T E V
Sbjct: 787 PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEV 846
Query: 242 LLFHQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ET 297
+ QILP+ D G C A N G +L ++ P P + E + ++ T
Sbjct: 847 ISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD---PPEIE---IKDVKART 900
Query: 298 IFLKTTIV--GKPTPT---IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L+ T+ G T IE ++ + R + ++P+ + I S +
Sbjct: 901 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTK-DVSPQLNSATIIDIHPSSTYSIR 959
Query: 353 IQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPPAD--DGGCKVG 406
+ AKN IG+ + +T+TA P PP+ V + +S+ + W+ P G +
Sbjct: 960 MYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI-IR 1018
Query: 407 NYIVEY--YRTGWNVWLKAI---TSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
Y + Y Y TG N I TS + V TL +L + ++Y ++A + G + PSS+
Sbjct: 1019 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGPSSQ 1077
Score = 39.1 bits (87), Expect = 0.084
Identities = 65/335 (19%), Positives = 127/335 (37%), Gaps = 32/335 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 1248 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 1302
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1358
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 1359 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 1409
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 1410 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1469
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 1470 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 1529
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
+ L+DL E + Y+ +++ + G + ++ +
Sbjct: 1530 SKSYILYDLQEATWYELQMRVCNSAGCAEKQAKEA 1564
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell
adhesion molecule protein.
Length = 1896
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 641 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 700
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 701 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 760
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 761 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 817
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 818 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 876
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 877 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 935
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 936 IHPSSTYSIRMYAKNRIGKSEPSNE 960
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 1289 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 1347
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 1348 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 1405
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 1406 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1444
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 871 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 926
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+L + + P Y R+ A N +G SE S+ LT+++D A+ + P LE ++
Sbjct: 927 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPIS 983
Query: 196 A 196
+
Sbjct: 984 S 984
Score = 52.4 bits (120), Expect = 8e-06
Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
SD A+ P + + + A+ +VE G P P W KD+ + S R
Sbjct: 204 SDPANSAPSI-LDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRF----Q 258
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEIN 295
++ + LL I PSD G C +NR G A RL ++ K PR+ + +
Sbjct: 259 KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS----SVG 314
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ L ++ G + W +G + + I+ +++ H K SD G YQ
Sbjct: 315 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVK-SDGGAYQ 370
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 484 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 540
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 541 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 597
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 598 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 657
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 658 RNEAAAVEHQSQLIVRVPP 676
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 604 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 663
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 664 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 720
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 721 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 773
Score = 46.0 bits (104), Expect = 7e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 1365 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 1420
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 1421 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 1474
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+V ++ I F +Y F + T TT + TS+
Sbjct: 1475 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSL 1515
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 316 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 374
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 375 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 431
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 432 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 491
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 492 SIRPMKNIT 500
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 393 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 452
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 453 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 508
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 509 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 567
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 568 QLSTSQSVHVTVKVPP 583
Score = 41.1 bits (92), Expect = 0.021
Identities = 72/365 (19%), Positives = 136/365 (37%), Gaps = 34/365 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 1234 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 1288
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 1289 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1344
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 1345 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 1395
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 1396 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1455
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 1456 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 1515
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEAL 487
+ L+DL E + Y+ +++ + G + + + + G I +V E L
Sbjct: 1516 SKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQN--EEGL 1573
Query: 488 TREDG 492
T +G
Sbjct: 1574 TTNEG 1578
Score = 39.5 bits (88), Expect = 0.063
Identities = 77/300 (25%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 185 PVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDE-STSV 241
P I + T A + K E T G + W K+D I R ++T E V
Sbjct: 773 PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEV 832
Query: 242 LLFHQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ET 297
+ QILP+ D G C A N G +L ++ P P + E + ++ T
Sbjct: 833 ISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD---PPEIE---IKDVKART 886
Query: 298 IFLKTTIV--GKPTPT---IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L+ T+ G T IE ++ + R + ++P+ + I S +
Sbjct: 887 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTK-DVSPQLNSATIIDIHPSSTYSIR 945
Query: 353 IQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPPAD--DGGCKVG 406
+ AKN IG+ + +T+TA P PP+ V + +S+ + W+ P G +
Sbjct: 946 MYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI-IR 1004
Query: 407 NYIVEY--YRTGWNVWLKAI---TSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
Y + Y Y TG N I TS + V TL +L + ++Y ++A + G + PSS+
Sbjct: 1005 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGPSSQ 1063
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 106 HDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSN 165
+DGG P+ + +E G+T W TA L +L L+ Y+ ++ N G +
Sbjct: 1486 NDGGCPITSFTLEYRPFGTTVW-TTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCA- 1543
Query: 166 YSELSDVLTVSSDRASQEPPVFIKRLEDVTAL-ENDKVEFHVTFSGI 211
+ ++ T++ D S PP+ +++ L N+ ++ VT S I
Sbjct: 1544 -EKQANFATLNYD-GSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCI 1588
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell
adhesion molecule isoform CHD2-42 precursor variant
protein.
Length = 2023
Score = 74.9 bits (176), Expect = 1e-12
Identities = 76/325 (23%), Positives = 130/325 (40%), Gaps = 23/325 (7%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQ----EPPVFIKRLEDVTALENDKVEFHVTFS 209
R++ L+ + + NY+ ++ + + SQ PP F+ + D + V + +
Sbjct: 666 RISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAE 725
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDE---STSVLLFHQILPSDEGEIKCTATNRGGH 265
G P PTI W F + + A+ S LL ++ D G C +N G
Sbjct: 726 GYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGA 785
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
V+K+ P + Y + L + + T G+ + W + II +
Sbjct: 786 DVSKSMYLTVKIPAMI--TSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDR-IINPE 842
Query: 326 RIEISITPK------FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
++ K S L+I R D G + A N GED +TV PPDPP
Sbjct: 843 MARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPDPP-E 901
Query: 380 VSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR--TGWN--VWLKAITSRKTNVTLFD 435
+ + +++TL W DG + Y +E W+ K ++ + + T+ D
Sbjct: 902 IEIKDVKARTITLRW-TMGFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID 960
Query: 436 LIEGSEYKFRIKAESPYGMSAPSSE 460
+ S Y R+ A++ G S PS+E
Sbjct: 961 IHPSSTYSIRMYAKNRIGKSEPSNE 985
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 1314 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 1372
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 1373 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 1430
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 1431 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1469
Score = 53.6 bits (123), Expect = 4e-06
Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 177 SDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTD 236
SD A+ P + + E A+ +VE G P P W KD+ + S R
Sbjct: 229 SDPANSAPSI-LDGFEHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRF----Q 283
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRY-PRQYEDGLLYEIN 295
++ + LL I PSD G C +NR G A RL ++ K PR+ + +
Sbjct: 284 KTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKS----SVG 339
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ L ++ G + W +G + + I+ +++ H K SD G YQ
Sbjct: 340 SQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVK-SDGGAYQ 395
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/121 (29%), Positives = 58/121 (47%), Gaps = 10/121 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP P+I + D + ITL+W DG +P+ GY +EC S W + P
Sbjct: 896 PPDPPEIE--IKDVKARTITLRWTMG-FDGNSPITGYDIECKN-KSDSWDSAQRTKDVSP 951
Query: 139 EL---VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+L + + P Y R+ A N +G SE S+ LT+++D A+ + P LE ++
Sbjct: 952 QLNSATIIDIHPSSTYSIRMYAKNRIGK---SEPSNELTITADEAAPDGPPQEVHLEPIS 1008
Query: 196 A 196
+
Sbjct: 1009 S 1009
Score = 50.4 bits (115), Expect = 3e-05
Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 9/199 (4%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDE 237
R + P I+ ++++TA+ H G P +I W+K+ + F+ R+ A E
Sbjct: 509 RINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAF---E 565
Query: 238 STSVLLFHQILPS-DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
+ L + DEGE C + + +++ P P ++ + I +
Sbjct: 566 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFP---RFSIGQ 622
Query: 297 TIFLKTTIVGKPTP-TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+F+ +V P TI W+ DG PI + I S L+I + G Y A
Sbjct: 623 RVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIA 682
Query: 356 KNIIGEDTAAFLVTVTAPP 374
+N + V PP
Sbjct: 683 RNEAAAVEHQSQLIVRVPP 701
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/176 (25%), Positives = 66/176 (37%), Gaps = 14/176 (7%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG TI W KD I S I + TS L + G C A N
Sbjct: 629 VVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAA 688
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDG------- 318
+++L + PK + +DG+ + + L + G P PTI W+
Sbjct: 689 VEHQSQLIVRVPPKFVVQPRDQDGI---YGKAVILNCSAEGYPVPTIVWKFSKGAGVPQF 745
Query: 319 HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAP 373
PI + RI++ L I D G Y + N +G D + + +TV P
Sbjct: 746 QPIALNGRIQVLSN---GSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIP 798
Score = 46.0 bits (104), Expect = 7e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 1390 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 1445
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 1446 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 1499
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+V ++ I F +Y F + T TT + TS+
Sbjct: 1500 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSL 1540
Score = 44.4 bits (100), Expect = 0.002
Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 201 KVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+V + +G ++W+++ + + IT ++++ H + SD G +C
Sbjct: 341 QVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMV-KSDGGAYQCFVR 399
Query: 261 NRGGHAVTKARLCLE-AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
A ++ LE PK+ + + ++ E + L + G P PTI W D
Sbjct: 400 KDKLSAQDYVQVVLEDGTPKII--SAFSEKVVSPA-EPVSLMCNVKGTPLPTITWTLDDD 456
Query: 320 PIIT--DDRIEISITPK---FSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
PI+ RI IT + S L I S++ D G Y+ A N G + V P
Sbjct: 457 PILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPA 516
Query: 375 D--PPRNVS 381
P +N++
Sbjct: 517 SIRPMKNIT 525
Score = 41.5 bits (93), Expect = 0.016
Identities = 45/196 (22%), Positives = 74/196 (37%), Gaps = 11/196 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF---SSRRTAITTDES--T 239
P I + + V G P PTI W DD I S R + + T E
Sbjct: 418 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 477
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S L D G +CTA N G + +AR+ + +R P + + +
Sbjct: 478 SYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIR-PMK---NITAIAGRDTY 533
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ ++G P +I+W + + + + R +++ ++ K D GEY
Sbjct: 534 IHCRVIGYPYYSIKWYKNSNLLPFNHR-QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 592
Query: 360 GEDTAAFL-VTVTAPP 374
T+ + VTV PP
Sbjct: 593 QLSTSQSVHVTVKVPP 608
Score = 41.1 bits (92), Expect = 0.021
Identities = 72/365 (19%), Positives = 136/365 (37%), Gaps = 34/365 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 1259 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 1313
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 1314 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 1369
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 1370 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 1420
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 1421 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 1480
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 1481 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 1540
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEAL 487
+ L+DL E + Y+ +++ + G + + + + G I +V E L
Sbjct: 1541 SKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQN--EEGL 1598
Query: 488 TREDG 492
T +G
Sbjct: 1599 TTNEG 1603
Score = 39.5 bits (88), Expect = 0.063
Identities = 77/300 (25%), Positives = 126/300 (42%), Gaps = 33/300 (11%)
Query: 185 PVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDE-STSV 241
P I + T A + K E T G + W K+D I R ++T E V
Sbjct: 798 PAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEV 857
Query: 242 LLFHQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ET 297
+ QILP+ D G C A N G +L ++ P P + E + ++ T
Sbjct: 858 ISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQEPPD---PPEIE---IKDVKART 911
Query: 298 IFLKTTIV--GKPTPT---IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
I L+ T+ G T IE ++ + R + ++P+ + I S +
Sbjct: 912 ITLRWTMGFDGNSPITGYDIECKNKSDSWDSAQRTK-DVSPQLNSATIIDIHPSSTYSIR 970
Query: 353 IQAKNIIGEDTAAFLVTVTA----PPDPPRNVSVTRQVDKSVTLDWEPPAD--DGGCKVG 406
+ AKN IG+ + +T+TA P PP+ V + +S+ + W+ P G +
Sbjct: 971 MYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGI-IR 1029
Query: 407 NYIVEY--YRTGWNVWLKAI---TSRKTNV-TLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
Y + Y Y TG N I TS + V TL +L + ++Y ++A + G + PSS+
Sbjct: 1030 GYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGPSSQ 1088
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 106 HDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSN 165
+DGG P+ + +E G+T W TA L +L L+ Y+ ++ N G +
Sbjct: 1511 NDGGCPITSFTLEYRPFGTTVW-TTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCA- 1568
Query: 166 YSELSDVLTVSSDRASQEPPVFIKRLEDVTAL-ENDKVEFHVTFSGI 211
+ ++ T++ D S PP+ +++ L N+ ++ VT S I
Sbjct: 1569 -EKQANFATLNYD-GSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCI 1613
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 74.1 bits (174), Expect = 2e-12
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 10/183 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T +G P+P IAW KD D+ RR + D+ V
Sbjct: 599 PSFTKTPHDITIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD--DV 656
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ D G CTA N G A L + P L P ED ++ + ET+ L+
Sbjct: 657 FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP--LEDRVV-SVGETVALQ 713
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P I W P+ +R +TP +L + + D G Y + N +G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHH--LTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 362 DTA 364
+ A
Sbjct: 772 ERA 774
Score = 49.2 bits (112), Expect = 8e-05
Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 9/142 (6%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEIN 295
E T++L Q+ EG +C TN G + KARL + P + + D +
Sbjct: 557 EYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPS--FTKTPHD-ITIRTT 613
Query: 296 ETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
L+ G P P I W+ DG P + R+ + P V I K D G Y
Sbjct: 614 TMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVM--PDDDVFFITDVKIDDAGVYS 671
Query: 353 IQAKNIIGEDTAAFLVTVTAPP 374
A+N G +A +TV P
Sbjct: 672 CTAQNSAGSISANATLTVLETP 693
Score = 40.7 bits (91), Expect = 0.027
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P + LED + V +G P P I WFK D + + R +T D +L
Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLL 748
Query: 243 LFHQILPSDEGEIKCTATNRGG 264
+ ++ D G C +N G
Sbjct: 749 VVQNVVAEDAGRYTCEMSNTLG 770
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 73.7 bits (173), Expect = 3e-12
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 10/183 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T +G P+P IAW KD D+ RR + D+ V
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD--DV 656
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ D G CTA N G A L + P L P ED ++ + ET+ L+
Sbjct: 657 FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP--LEDRVV-SVGETVALQ 713
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P I W P+ +R +TP +L + + D G Y + N +G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHH--LTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 362 DTA 364
+ A
Sbjct: 772 ERA 774
Score = 49.6 bits (113), Expect = 6e-05
Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 9/142 (6%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEIN 295
E T++L Q+ EG +C TN G + KARL + P + + D +
Sbjct: 557 EYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPS--FTKTPHD-ITIRTT 613
Query: 296 ETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
L+ G P P I W+ DG P + R+ + P V I K D G Y
Sbjct: 614 TVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVM--PDDDVFFITDVKIDDAGVYS 671
Query: 353 IQAKNIIGEDTAAFLVTVTAPP 374
A+N G +A +TV P
Sbjct: 672 CTAQNSAGSISANATLTVLETP 693
Score = 40.7 bits (91), Expect = 0.027
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P + LED + V +G P P I WFK D + + R +T D +L
Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLL 748
Query: 243 LFHQILPSDEGEIKCTATNRGG 264
+ ++ D G C +N G
Sbjct: 749 VVQNVVAEDAGRYTCEMSNTLG 770
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 73.7 bits (173), Expect = 3e-12
Identities = 62/208 (29%), Positives = 90/208 (43%), Gaps = 8/208 (3%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
S+ R + P + + + E + AL D SGIP P + WFK D E+ S T +
Sbjct: 35 STLRYIEAPKLMVVQSELLVAL-GDITVMECKTSGIPPPQVKWFKGDLELRPS--TFLII 91
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
D +L + D G+ C A N G A K L + + P Q + EI
Sbjct: 92 DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVF---IQEPADVSMEIG 148
Query: 296 ETIFLKTTIVGKPTPTIEWRH-DGHPIITDDRIEISITP-KFSVLKIHSAKRSDRGEYQI 353
+ L + G P PTI+WR D PI + SI+ + L I + SD+G Y
Sbjct: 149 SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYIC 208
Query: 354 QAKNIIGEDTAAFLVTVTAPPDPPRNVS 381
+A+N G+ + VTVT P +S
Sbjct: 209 EAENQFGKIQSETTVTVTGLVAPLIGIS 236
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/195 (24%), Positives = 75/195 (38%), Gaps = 9/195 (4%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-DDYEIFSSRRTAITTDE-STSV 241
PPVFI+ DV+ V G P PTI W + D+ IFS + + + T
Sbjct: 133 PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGA 192
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE--AAPKLRYPRQYEDGLLYEINETIF 299
L + SD+G C A N+ G ++ + + AP + + + E +
Sbjct: 193 LFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVAN--VIEGQQLTL 250
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
T + G P P W + ++ + I + L I + D GEY A N+
Sbjct: 251 PCTLLAGNPIPERRWIKNSAMLLQNPYITVR---SDGSLHIERVQLQDGGEYTCVASNVA 307
Query: 360 GEDTAAFLVTVTAPP 374
G + V V P
Sbjct: 308 GTNNKTTSVVVHVLP 322
Score = 50.8 bits (116), Expect = 3e-05
Identities = 50/184 (27%), Positives = 76/184 (41%), Gaps = 13/184 (7%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE- 252
++ +E V SG P P++ W K E+ S+ + S+ + + P E
Sbjct: 331 LSTIEGIPVTLPCKASGNPKPSVIWSKKG-ELISTSSAKFSAGADGSLYV---VSPGGEE 386
Query: 253 -GEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEIN----ETIFLKTTIVG 306
GE CTATN G+A K +L + P++ R EI+ E + L +
Sbjct: 387 SGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKS 446
Query: 307 KPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P P I W + +I+ + P S +KI + SD G Y A NI G T A
Sbjct: 447 LPPPIITWAKETQ-LISPFSPRHTFLPSGS-MKITETRTSDSGMYLCVATNIAGNVTQAV 504
Query: 367 LVTV 370
+ V
Sbjct: 505 KLNV 508
Score = 47.6 bits (108), Expect = 2e-04
Identities = 43/158 (27%), Positives = 63/158 (39%), Gaps = 10/158 (6%)
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET 297
S L P D G C A+N G + L APKL + LL + +
Sbjct: 3 SDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV---VQSELLVALGDI 59
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ G P P ++W G + I I P +LKI + D G+Y A N
Sbjct: 60 TVMECKTSGIPPPQVKW-FKGDLELRPSTFLI-IDPLLGLLKIQETQDLDAGDYTCVAIN 117
Query: 358 IIGEDTAAFLVTVTAPP---DPPRNVSVTRQVDKSVTL 392
G T + V +PP P +VS+ ++ +VTL
Sbjct: 118 EAGRATGKITLDVGSPPVFIQEPADVSM--EIGSNVTL 153
Score = 32.3 bits (70), Expect = 9.6
Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 6/82 (7%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPS 250
+++ L ++V +P P I W K+ I FS R T + + + + S
Sbjct: 429 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS----MKITETRTS 484
Query: 251 DEGEIKCTATNRGGHAVTKARL 272
D G C ATN G+ +L
Sbjct: 485 DSGMYLCVATNIAGNVTQAVKL 506
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 73.7 bits (173), Expect = 3e-12
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 10/183 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T +G P+P IAW KD D+ RR + D+ V
Sbjct: 599 PSFTKTPHDITIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDD--DV 656
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+ D G CTA N G A L + P L P ED ++ + ET+ L+
Sbjct: 657 FFITDVKIDDAGVYSCTAQNSAGSISANATLTVLETPSLVVP--LEDRVV-SVGETVALQ 713
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P I W P+ +R +TP +L + + D G Y + N +G
Sbjct: 714 CKATGNPPPRITWFKGDRPLSLTERHH--LTPDNQLLVVQNVVAEDAGRYTCEMSNTLGT 771
Query: 362 DTA 364
+ A
Sbjct: 772 ERA 774
Score = 49.6 bits (113), Expect = 6e-05
Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 9/142 (6%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEIN 295
E T++L Q+ EG +C TN G + KARL + P + + D +
Sbjct: 557 EYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPS--FTKTPHD-ITIRTT 613
Query: 296 ETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
L+ G P P I W+ DG P + R+ + P V I K D G Y
Sbjct: 614 TVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVM--PDDDVFFITDVKIDDAGVYS 671
Query: 353 IQAKNIIGEDTAAFLVTVTAPP 374
A+N G +A +TV P
Sbjct: 672 CTAQNSAGSISANATLTVLETP 693
Score = 40.7 bits (91), Expect = 0.027
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P + LED + V +G P P I WFK D + + R +T D +L
Sbjct: 691 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLL 748
Query: 243 LFHQILPSDEGEIKCTATNRGG 264
+ ++ D G C +N G
Sbjct: 749 VVQNVVAEDAGRYTCEMSNTLG 770
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 72.5 bits (170), Expect = 7e-12
Identities = 70/288 (24%), Positives = 111/288 (38%), Gaps = 8/288 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS-SRRTAITTDESTSVLL 243
PVF +R D T + SG P P I W ++++ + S S R + L
Sbjct: 480 PVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQ 539
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ D G C A N G A L + + +P + + ++ T+ T
Sbjct: 540 IAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPE-DHVVIKGTTATLHCGAT 598
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ + W+ D + I + S+L I D G+Y + + G D+
Sbjct: 599 HDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLL-ISQTWSGDIGDYSCEIVSEGGNDS 657
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKS--VTLDWEPPADDGGCKVGNYIVEYYRTG--WNV 419
+ V P P+N+ V+ S V L W P D G + YIVE W V
Sbjct: 658 RMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFD-GNSPILYYIVELSENSSPWKV 716
Query: 420 WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIP 467
L + T VT+ L Y+FR+ A + G S+E+S + +P
Sbjct: 717 HLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLP 764
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/191 (26%), Positives = 79/191 (41%), Gaps = 7/191 (3%)
Query: 183 EPPVFIKRLED-VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP F E ++A + V+ G+P PT+ W+KD I + S
Sbjct: 384 EPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGG- 442
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ P D G +C A+N GG T L AP + ++ D + + T L
Sbjct: 443 LRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPV--FTQRPVDTTVTD-GMTAIL 499
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDD-RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ + G P P I W+ + H + + RI + + L+I D G Y A N
Sbjct: 500 RCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTE 559
Query: 360 GEDTAAFLVTV 370
G A+ +TV
Sbjct: 560 GSLNASATLTV 570
Score = 52.8 bits (121), Expect = 6e-06
Identities = 33/111 (29%), Positives = 57/111 (51%), Gaps = 5/111 (4%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
RPAPP + ++P ++ ++ L+W P + DG +P+R + ++ L EW + I
Sbjct: 1476 RPAPP-RELLVP-QAEVTARSLRLQWVPGS-DGASPIRYFTMQVRELPRGEWQTYSSSIS 1532
Query: 136 LRPEL-VLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V+ L P Y+ R+ A ND+G S++S ++ +T D EPP
Sbjct: 1533 HEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQD-VPGEPP 1582
Score = 48.0 bits (109), Expect = 2e-04
Identities = 55/289 (19%), Positives = 118/289 (40%), Gaps = 14/289 (4%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTI--AWFKDDYEIFSSRRTAITTDESTSVLLFHQILP 249
ED ++ H + P ++ W KD+ + S + I ++ S LL Q
Sbjct: 581 EDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGS-LLISQTWS 639
Query: 250 SDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D G+ C + GG+ ARL + P + + G +
Sbjct: 640 GDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGN-S 698
Query: 310 PTIEWRHDGHPIITDDRIEIS-ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE-----DT 363
P + + + + ++ +S + P+ + + + + ++++ A N +G +T
Sbjct: 699 PILYYIVELSENSSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAET 758
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPAD-DGGCKVGNYIVEYYRTG--WNVW 420
+ ++ P PP+N+ + + ++S+ + W+PP + + + YI+ Y G
Sbjct: 759 SRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQ 818
Query: 421 LKAITSRKTNVTLF-DLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
+ ITS + N L DLI ++Y+ ++ A + G+ S + + G
Sbjct: 819 QRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQG 867
Score = 46.4 bits (105), Expect = 6e-04
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Query: 80 PGKPQIIPIL-SDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
P PQ + + + +A+ L W DG +P+ Y VE + S + +
Sbjct: 668 PHSPQNLLVSPNSSHSHAVVLSWV-RPFDGNSPILYYIVELSENSSPWKVHLSNVGPEMT 726
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEP 184
+ ++GL P YQFRV A+N+VG YS + L + + S P
Sbjct: 727 GVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPP 772
Score = 43.2 bits (97), Expect = 0.005
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 10/135 (7%)
Query: 338 LKIHSAKRSDRGEYQIQAKNII-GEDTAAFLVTVTAPPDP--PRNVSVTRQVDKSVTLDW 394
LK+ + +++QA+ I G + A + A P PR+V VT+ + +TL W
Sbjct: 1864 LKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASE-LTLQW 1922
Query: 395 EPPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTNVTLF--DLIEGSEYKFRIKAE 449
G Y++E + W++++K I T+ TL L +G Y+FR+ A
Sbjct: 1923 TE-GHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAV 1981
Query: 450 SPYGMSAPSSESSPV 464
+ G PS+ S+ V
Sbjct: 1982 NEAGYGEPSNPSTAV 1996
Score = 42.3 bits (95), Expect = 0.009
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 12/140 (8%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W +DD E+ TT S + + D G +C NR G A+ + + ++ A
Sbjct: 138 WMRDDSEL--------TTYSSEYKYIIPSLQKLDAGFYRCVVRNRMG-ALLQRKSEVQVA 188
Query: 278 PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV 337
+ + + + I I P P + W +GH II +RI I++ + +
Sbjct: 189 YMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVI 248
Query: 338 LKIHSAKRSDRGEYQIQAKN 357
L + SD G Y +QA N
Sbjct: 249 L---ATTTSDAGAYYVQAVN 265
Score = 40.7 bits (91), Expect = 0.027
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW---IRTAPPIVL 136
PG P+ +L + +TL+W H G P GY +E W ++ P
Sbjct: 1903 PGSPR--DVLVTKSASELTLQWTEG-HSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSAT 1959
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLT 174
L L L Y+FRV A+N+ G+ S S ++
Sbjct: 1960 SYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVS 1997
Score = 37.1 bits (82), Expect = 0.34
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 8/112 (7%)
Query: 360 GEDTAAFLVTVTAP--PDPPRNVSVTRQ--VDKSVTLDWEPPADDGGCKVGNYIV---EY 412
GE A ++T P PPR + V + +S+ L W P DG + + + E
Sbjct: 1461 GEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVP-GSDGASPIRYFTMQVREL 1519
Query: 413 YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
R W + +I+ T + L + YK R+KA + G S SSE+ V
Sbjct: 1520 PRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAV 1571
Score = 36.3 bits (80), Expect = 0.59
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 352 QIQAKNIIGE-----DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADD 400
+++A N IG+ +T A P +PP +VS T SV + W+PP D+
Sbjct: 1552 RLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDE 1605
Score = 35.9 bits (79), Expect = 0.78
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 13/104 (12%)
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV-----LKIH 341
E + E+ ET+ + +G P PT++W D I+ R++ P++ V L+I
Sbjct: 393 ESRISAEVEETVDIGCQAMGVPLPTLQWYKDA---ISISRLQ---NPRYKVLASGGLRIQ 446
Query: 342 SAKRSDRGEYQIQAKNIIGE-DTAAFL-VTVTAPPDPPRNVSVT 383
+ D G +Q A N GE T +L VT AP R V T
Sbjct: 447 KLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTT 490
Score = 35.1 bits (77), Expect = 1.4
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 344 KRSDRGEYQIQAKNIIGEDTAAFLVTV----TAPPDPPRNVSVTRQVDKSVTLDWEPPAD 399
K+ R E + A NIIGE A+ V V AP P+NV VT + + W+PP
Sbjct: 1668 KKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPP 1727
Query: 400 DG-GCKVGNYIVEYY 413
+ + Y + Y+
Sbjct: 1728 ESQNGNIQGYKIYYW 1742
Score = 32.3 bits (70), Expect = 9.6
Identities = 36/163 (22%), Positives = 63/163 (38%), Gaps = 15/163 (9%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN-RGGHAVTKA 270
P P + WF++ ++I S R AIT + +L SD G A N + G T
Sbjct: 219 PRPQVTWFREGHKIIPSNRIAITLENQLVIL---ATTTSDAGAYYVQAVNEKNGENKTSP 275
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
+ L A + P ++ ++ + G T+E P+ ++S
Sbjct: 276 FIHLSIARDVGTPETMAPTIVVPPGN----RSVVAGSSETTLECIASARPV-----EDLS 326
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP 373
+T K + ++I S S G + + N DT ++ P
Sbjct: 327 VTWKRNGVRITSGLHS-FGRH-LTISNPTSADTGPYVCEAALP 367
>AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down
syndrome cell adhesion molecule protein.
Length = 1029
Score = 72.1 bits (169), Expect = 1e-11
Identities = 50/159 (31%), Positives = 74/159 (46%), Gaps = 6/159 (3%)
Query: 298 IFLKTTIVGKPTPTIEWRHD--GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
I L VG P+P ++W D G P + SI S + I + K D G Y A
Sbjct: 320 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFI-IRTVKAEDSGYYSCIA 378
Query: 356 KNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
N G D + V PPD PR ++V++ S+TL W P D+GG + YI++Y
Sbjct: 379 NNNWGSDEIILNLQVQVPPDQPR-LTVSKTTSSSITLSW-LPGDNGGSSIRGYILQYSED 436
Query: 416 GWNVWLK-AITSRKTNVTLFDLIEGSEYKFRIKAESPYG 453
W I+ + + L +L G+ YKF + A++ G
Sbjct: 437 NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 475
Score = 46.0 bits (104), Expect = 7e-04
Identities = 42/163 (25%), Positives = 72/163 (44%), Gaps = 12/163 (7%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
PP +P++ +S ++ITL W P + GG+ +RGY ++ + S +W + P
Sbjct: 396 PPDQPRLT--VSKTTSSSITLSWLPGDN-GGSSIRGYILQYSEDNSEQW-GSFPISPSER 451
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALE 198
L L+ Y+F + A N VG SE+ + T+ + P F K E ++
Sbjct: 452 SYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE------PQFSKEQELFASIN 505
Query: 199 NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
+V ++ I F +Y F + T TT + TS+
Sbjct: 506 TTRVRLNLIGWNDGGCPITSFTLEYRPFGT--TVWTTAQRTSL 546
Score = 41.1 bits (92), Expect = 0.021
Identities = 72/365 (19%), Positives = 136/365 (37%), Gaps = 34/365 (9%)
Query: 142 LTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDK 201
+ L +Y V A+ G N SE ++TV + ++ P + VT
Sbjct: 265 IPNLSRNRQYSVWVVAVTSAGRGNSSE---IITV--EPLAKAPARILTFSGTVTTPWMKD 319
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL-----LFHQILPSDEGEIK 256
+ G PSP + W KD + + +T D S+ + + D G
Sbjct: 320 IVLPCKAVGDPSPAVKWMKDS----NGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYS 375
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G L ++ P PR +++T T+ P
Sbjct: 376 CIANNNWGSDEIILNLQVQVPPD--QPR-------LTVSKTTSSSITLSWLPGDNGGSSI 426
Query: 317 DGHPI-ITDDRIE----ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV--- 368
G+ + ++D E I+P ++ + K ++ + A+N +G + ++
Sbjct: 427 RGYILQYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAK 486
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA-ITSR 427
T+ P + + ++ + +DGGC + ++ +EY G VW A TS
Sbjct: 487 TLGKEPQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSL 546
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEAL 487
+ L+DL E + Y+ +++ + G + + + + G I +V E L
Sbjct: 547 SKSYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLIKSVVQN--EEGL 604
Query: 488 TREDG 492
T +G
Sbjct: 605 TTNEG 609
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 106 HDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSN 165
+DGG P+ + +E G+T W TA L +L L+ Y+ ++ N G +
Sbjct: 517 NDGGCPITSFTLEYRPFGTTVW-TTAQRTSLSKSYILYDLQEATWYELQMRVCNSAGCA- 574
Query: 166 YSELSDVLTVSSDRASQEPPVFIKRLEDVTAL-ENDKVEFHVTFSGI 211
+ ++ T++ D S PP+ +++ L N+ ++ VT S I
Sbjct: 575 -EKQANFATLNYD-GSTIPPLIKSVVQNEEGLTTNEGLKMLVTISCI 619
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 8/198 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q P F +D +E V+F G P P IAW K ++ RR + S+
Sbjct: 447 QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVL---SSGT 503
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D+G+ +C A N G A L ++ + D + E+ + L
Sbjct: 504 LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTV-EVGANVQLP 562
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G+P P I W DG + + IS P+ L I+ +D G Y+ A+N IG
Sbjct: 563 CSSQGEPEPAITWNKDGVQVTESGKFHIS--PE-GFLTINDVGPADAGRYECVARNTIGS 619
Query: 362 DTAAFLVTVTAPPDPPRN 379
+ + +++V PD RN
Sbjct: 620 ASVSMVLSVNV-PDVSRN 636
Score = 66.9 bits (156), Expect = 4e-10
Identities = 55/223 (24%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--- 241
P F+ + ++ L + V + +G P P I+W + D RT + D ++
Sbjct: 359 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGD-------RTPLPVDPRVNITPS 411
Query: 242 --LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L ++ D GE C+ATN A + ++A P+ Q D ++ E +T+
Sbjct: 412 GGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ--DRVVIE-GQTVD 468
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ G P P I W G + D R + L+I D+G+Y+ QA NII
Sbjct: 469 FQCEAKGNPPPVIAWTKGGSQLSVDRR---HLVLSSGTLRISGVALHDQGQYECQAVNII 525
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGG 402
G +TV P P S+ V + + P G
Sbjct: 526 GSQKVVAHLTV-QPRVTPVFASIPSDTTVEVGANVQLPCSSQG 567
Score = 62.9 bits (146), Expect = 6e-09
Identities = 56/209 (26%), Positives = 85/209 (40%), Gaps = 14/209 (6%)
Query: 172 VLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
V T++ + + E P +D + V F G P P I W +++ E+ +
Sbjct: 250 VATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS 309
Query: 232 AIT-TDESTSVLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQY 286
+ D+ T L+ +D+G +C A N G VT A P Q
Sbjct: 310 RLNLLDDGT--LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 367
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
+ L + E++ L+ + G P P I W R D P+ D R ++ITP L I + +
Sbjct: 368 TEVL---VGESVTLECSATGHPPPRISWTRGDRTPLPVDPR--VNITPS-GGLYIQNVVQ 421
Query: 346 SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D GEY A N I A + V A P
Sbjct: 422 GDSGEYACSATNNIDSVHATAFIIVQALP 450
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 8/198 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q P F +D +E V+F G P P IAW K ++ RR + S+
Sbjct: 425 QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVL---SSGT 481
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D+G+ +C A N G A L ++ + D + E+ + L
Sbjct: 482 LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTV-EVGANVQLP 540
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G+P P I W DG + + IS P+ L I+ +D G Y+ A+N IG
Sbjct: 541 CSSQGEPEPAITWNKDGVQVTESGKFHIS--PE-GFLTINDVGPADAGRYECVARNTIGS 597
Query: 362 DTAAFLVTVTAPPDPPRN 379
+ + +++V PD RN
Sbjct: 598 ASVSMVLSVNV-PDVSRN 614
Score = 66.9 bits (156), Expect = 4e-10
Identities = 55/223 (24%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--- 241
P F+ + ++ L + V + +G P P I+W + D RT + D ++
Sbjct: 337 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGD-------RTPLPVDPRVNITPS 389
Query: 242 --LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L ++ D GE C+ATN A + ++A P+ Q D ++ E +T+
Sbjct: 390 GGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ--DRVVIE-GQTVD 446
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ G P P I W G + D R + L+I D+G+Y+ QA NII
Sbjct: 447 FQCEAKGNPPPVIAWTKGGSQLSVDRR---HLVLSSGTLRISGVALHDQGQYECQAVNII 503
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGG 402
G +TV P P S+ V + + P G
Sbjct: 504 GSQKVVAHLTV-QPRVTPVFASIPSDTTVEVGANVQLPCSSQG 545
Score = 62.9 bits (146), Expect = 6e-09
Identities = 56/209 (26%), Positives = 85/209 (40%), Gaps = 14/209 (6%)
Query: 172 VLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
V T++ + + E P +D + V F G P P I W +++ E+ +
Sbjct: 228 VATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS 287
Query: 232 AIT-TDESTSVLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQY 286
+ D+ T L+ +D+G +C A N G VT A P Q
Sbjct: 288 RLNLLDDGT--LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 345
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
+ L + E++ L+ + G P P I W R D P+ D R ++ITP L I + +
Sbjct: 346 TEVL---VGESVTLECSATGHPPPRISWTRGDRTPLPVDPR--VNITPS-GGLYIQNVVQ 399
Query: 346 SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D GEY A N I A + V A P
Sbjct: 400 GDSGEYACSATNNIDSVHATAFIIVQALP 428
>AK129856-1|BAC85243.1| 295|Homo sapiens protein ( Homo sapiens
cDNA FLJ26346 fis, clone HRT04038, highly similar to
Homo sapiens titin (TTN), transcript variant N2-B. ).
Length = 295
Score = 71.7 bits (168), Expect = 1e-11
Identities = 40/103 (38%), Positives = 52/103 (50%), Gaps = 2/103 (1%)
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
E V PPDPP+N VT S+ + W P DGG ++ NYIVE W
Sbjct: 13 ESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRW 72
Query: 421 LKAITSRKTNV--TLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+K T++ + L EG EY+FRI AE+ G+SAPS S
Sbjct: 73 IKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 115
Score = 60.9 bits (141), Expect = 2e-08
Identities = 38/150 (25%), Positives = 63/150 (42%), Gaps = 5/150 (3%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
+P PPG P+++ D ++I++ W +DGG+ + GY VE EW PP
Sbjct: 126 KPGPPGNPRVL----DTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAG 181
Query: 136 LR-PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
L+ +TGL +Y+ R+ A+N G + + E + + V
Sbjct: 182 LKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVV 241
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYE 224
T + V G P+P + W +D E
Sbjct: 242 TIRACCTLRLFVPIKGRPAPEVKWARDHGE 271
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/129 (27%), Positives = 53/129 (41%), Gaps = 9/129 (6%)
Query: 339 KIHSAKRSDRGEYQIQAKNIIG----EDTAAFLVTVTA--PPDPPRNVSVTRQVDKSVTL 392
K+ E++I A+N G T+ F P PP N V S+++
Sbjct: 86 KVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISI 145
Query: 393 DWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAE 449
W P DGG ++ Y+VE W + + T+ T+ L E EYK RI A
Sbjct: 146 AWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAM 205
Query: 450 SPYGMSAPS 458
+ G+ P+
Sbjct: 206 NSEGLGEPA 214
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP P++ I D ++ + W DGG+ + Y VE WI+
Sbjct: 24 GPPDPPKNPEVTTITKD----SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT 79
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
+ ++GL H+Y+FR+ A N G S S S
Sbjct: 80 LTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 115
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/406 (24%), Positives = 155/406 (38%), Gaps = 36/406 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWA-PATHDGGAPLRGYQVECNRLG-STEWIRTAPPIVL 136
PP + + I SD + W+ P L+GY+V L EW
Sbjct: 1153 PPENVRALSITSD----VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT 1208
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R + L G+E Y +V A G S VL + + PP IK + +
Sbjct: 1209 RERVELRGMEKFTNYSVQVLAYTQAGDG---VRSSVLYIQTKEDVPGPPAGIKAVPSSAS 1265
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDE 252
V S +P Y IF S + A + E++ LF++I +
Sbjct: 1266 --------SVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNR 1317
Query: 253 GE---IKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKP 308
G+ + A G + ++ +E A K + + + + L VG P
Sbjct: 1318 GQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1377
Query: 309 TPTIEWRHDGH----PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P ++W D P+ D I L + + K D G Y A N G DT
Sbjct: 1378 APAVKWTKDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAEDSGYYTCTATNTGGFDTI 1434
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA- 423
+ V PPD PR ++V++ S+TL W P D+GG + ++++Y W
Sbjct: 1435 IVNLLVQVPPDQPR-LTVSKTSASSITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDVF 1492
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I+S + + L L G+ YK ++ A++ G S SE + GR
Sbjct: 1493 ISSSERSFKLDSLKCGTWYKVKLAAKNSVG-SGRISEIIEAKTHGR 1537
Score = 59.7 bits (138), Expect = 6e-08
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 23/352 (6%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS--QEP 184
W + I+ + + E Q +L G+ + TVS +R + P
Sbjct: 690 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 749
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-----DDYEIFSSRRTAITTDEST 239
P F+ + + + + + G P P + W + + T
Sbjct: 750 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 809
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S LL +L D G C A+N G ++K+ P + + + +
Sbjct: 810 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI--TSHPNTTIAIKGHAKE 867
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPK------FSVLKIHSAKRSDRGEYQ 352
L T G+ I W G +I DR+ +I K S LK+ A R D +
Sbjct: 868 LNCTARGERPIIIRWEK-GDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFS 926
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
A N GED +TV PPDPP + + +S+ L W DG + + +EY
Sbjct: 927 CHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRW-TQRFDGNSIITGFDIEY 984
Query: 413 YR--TGWNV--WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
W+ + I+ + DL S Y R+ + + G S PS E
Sbjct: 985 KNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKE 1036
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/181 (28%), Positives = 71/181 (39%), Gaps = 12/181 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
VE T SG P P I W KD + + R T T L + D G C TN
Sbjct: 303 VELPCTASGYPIPAIRWLKDGRPLPADSRW---TKRITG-LTISDLRTEDSGTYICEVTN 358
Query: 262 RGGHA-VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
G A T + ++ P++ + G I T+ L + G P TI W +
Sbjct: 359 TFGSAEATGILMVIDPLHVTLTPKKLKTG----IGSTVILSCALTGSPEFTIRWYRNTEL 414
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
++ D+ I I ++L I SA++S G YQ A TA + PR V
Sbjct: 415 VLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIV 471
Query: 381 S 381
S
Sbjct: 472 S 472
Score = 52.4 bits (120), Expect = 8e-06
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 15/177 (8%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG I W KD I S I + E S L + G C A+N
Sbjct: 678 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT 737
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH--------D 317
+ +L + P+ +DG+ + L ++ G P P + W+H
Sbjct: 738 VSRERQLIVRVPPRFVVQPNNQDGI---YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 794
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTAP 373
HP+ RI+ I P S+L I D G Y QA N +G D + + +TV P
Sbjct: 795 YHPVPLTGRIQ--ILPNSSLL-IRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 848
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G P TI W+++ + +I S LL S G +C AT + A
Sbjct: 399 TGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 457
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD---- 324
A + LE R + + ++ E L G P PT+ W D PI+ D
Sbjct: 458 FAIIALEDGTP-RIVSSFSEKVVNP-GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHR 515
Query: 325 -DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
++ +S S + + + D G Y+ A+N++G + V PP
Sbjct: 516 TNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 566
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/197 (21%), Positives = 77/197 (39%), Gaps = 6/197 (3%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + P I+ + ++TA+ + G P +I W+KD + + R + E+
Sbjct: 559 RINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--EN 616
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
++ L DEGE C+ + +++++ P L P ++ I + +
Sbjct: 617 GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPA---SIGQLL 673
Query: 299 FLKTTIVGKPTPT-IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ + P I WR DG II+ + I S L+I S G Y A N
Sbjct: 674 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 733
Query: 358 IIGEDTAAFLVTVTAPP 374
+ + V PP
Sbjct: 734 AAATVSRERQLIVRVPP 750
Score = 46.0 bits (104), Expect = 7e-04
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 210 GIPSPTIAWFKDDYEIF---SSRRTAITTDESTSVLLFHQILPS--DEGEIKCTATNRGG 264
G P PT+ W DD I S R T + T++ + P D G +CTA N G
Sbjct: 493 GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVG 552
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
A +AR+ + P +R R + + ++G P +I+W D ++ D
Sbjct: 553 SAEYQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 607
Query: 325 DRIEISITPKFSVLKIHSAKRS-DRGEY 351
+ ++ + LK+ ++ D GEY
Sbjct: 608 NHRQVVF--ENGTLKLTDVQKGMDEGEY 633
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
T+ L T G P P I W DG P+ D R T + + L I + D G Y +
Sbjct: 302 TVELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVT 357
Query: 357 NIIGEDTAAFLVTVTAP 373
N G A ++ V P
Sbjct: 358 NTFGSAEATGILMVIDP 374
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule DSCAML1 protein.
Length = 2053
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/406 (24%), Positives = 155/406 (38%), Gaps = 36/406 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWA-PATHDGGAPLRGYQVECNRLG-STEWIRTAPPIVL 136
PP + + I SD + W+ P L+GY+V L EW
Sbjct: 1093 PPENVRALSITSD----VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT 1148
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R + L G+E Y +V A G S VL + + PP IK + +
Sbjct: 1149 RERVELRGMEKFTNYSVQVLAYTQAGDG---VRSSVLYIQTKEDVPGPPAGIKAVPSSAS 1205
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDE 252
V S +P Y IF S + A + E++ LF++I +
Sbjct: 1206 --------SVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNR 1257
Query: 253 GE---IKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKP 308
G+ + A G + ++ +E A K + + + + L VG P
Sbjct: 1258 GQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1317
Query: 309 TPTIEWRHDGH----PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P ++W D P+ D I L + + K D G Y A N G DT
Sbjct: 1318 APAVKWTKDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAEDSGYYTCTATNTGGFDTI 1374
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA- 423
+ V PPD PR ++V++ S+TL W P D+GG + ++++Y W
Sbjct: 1375 IVNLLVQVPPDQPR-LTVSKTSASSITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDVF 1432
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I+S + + L L G+ YK ++ A++ G S SE + GR
Sbjct: 1433 ISSSERSFKLDSLKCGTWYKVKLAAKNSVG-SGRISEIIEAKTHGR 1477
Score = 59.7 bits (138), Expect = 6e-08
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 23/352 (6%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS--QEP 184
W + I+ + + E Q +L G+ + TVS +R + P
Sbjct: 630 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 689
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-----DDYEIFSSRRTAITTDEST 239
P F+ + + + + + G P P + W + + T
Sbjct: 690 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 749
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S LL +L D G C A+N G ++K+ P + + + +
Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI--TSHPNTTIAIKGHAKE 807
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPK------FSVLKIHSAKRSDRGEYQ 352
L T G+ I W G +I DR+ +I K S LK+ A R D +
Sbjct: 808 LNCTARGERPIIIRWEK-GDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFS 866
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
A N GED +TV PPDPP + + +S+ L W DG + + +EY
Sbjct: 867 CHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRW-TQRFDGNSIITGFDIEY 924
Query: 413 YR--TGWNV--WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
W+ + I+ + DL S Y R+ + + G S PS E
Sbjct: 925 KNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKE 976
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/181 (28%), Positives = 71/181 (39%), Gaps = 12/181 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
VE T SG P P I W KD + + R T T L + D G C TN
Sbjct: 243 VELPCTASGYPIPAIRWLKDGRPLPADSRW---TKRITG-LTISDLRTEDSGTYICEVTN 298
Query: 262 RGGHA-VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
G A T + ++ P++ + G I T+ L + G P TI W +
Sbjct: 299 TFGSAEATGILMVIDPLHVTLTPKKLKTG----IGSTVILSCALTGSPEFTIRWYRNTEL 354
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
++ D+ I I ++L I SA++S G YQ A TA + PR V
Sbjct: 355 VLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIV 411
Query: 381 S 381
S
Sbjct: 412 S 412
Score = 52.4 bits (120), Expect = 8e-06
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 15/177 (8%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG I W KD I S I + E S L + G C A+N
Sbjct: 618 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT 677
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH--------D 317
+ +L + P+ +DG+ + L ++ G P P + W+H
Sbjct: 678 VSRERQLIVRVPPRFVVQPNNQDGI---YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTAP 373
HP+ RI+ I P S+L I D G Y QA N +G D + + +TV P
Sbjct: 735 YHPVPLTGRIQ--ILPNSSLL-IRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 788
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G P TI W+++ + +I S LL S G +C AT + A
Sbjct: 339 TGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 397
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD---- 324
A + LE R + + ++ E L G P PT+ W D PI+ D
Sbjct: 398 FAIIALEDGTP-RIVSSFSEKVVNP-GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHR 455
Query: 325 -DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
++ +S S + + + D G Y+ A+N++G + V PP
Sbjct: 456 TNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/197 (21%), Positives = 77/197 (39%), Gaps = 6/197 (3%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + P I+ + ++TA+ + G P +I W+KD + + R + E+
Sbjct: 499 RINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--EN 556
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
++ L DEGE C+ + +++++ P L P ++ I + +
Sbjct: 557 GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPA---SIGQLL 613
Query: 299 FLKTTIVGKPTPT-IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ + P I WR DG II+ + I S L+I S G Y A N
Sbjct: 614 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 673
Query: 358 IIGEDTAAFLVTVTAPP 374
+ + V PP
Sbjct: 674 AAATVSRERQLIVRVPP 690
Score = 46.0 bits (104), Expect = 7e-04
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 210 GIPSPTIAWFKDDYEIF---SSRRTAITTDESTSVLLFHQILPS--DEGEIKCTATNRGG 264
G P PT+ W DD I S R T + T++ + P D G +CTA N G
Sbjct: 433 GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVG 492
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
A +AR+ + P +R R + + ++G P +I+W D ++ D
Sbjct: 493 SAEYQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 547
Query: 325 DRIEISITPKFSVLKIHSAKRS-DRGEY 351
+ ++ + LK+ ++ D GEY
Sbjct: 548 NHRQVVF--ENGTLKLTDVQKGMDEGEY 573
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
T+ L T G P P I W DG P+ D R T + + L I + D G Y +
Sbjct: 242 TVELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVT 297
Query: 357 NIIGEDTAAFLVTVTAP 373
N G A ++ V P
Sbjct: 298 NTFGSAEATGILMVIDP 314
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1b protein.
Length = 1842
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/406 (24%), Positives = 155/406 (38%), Gaps = 36/406 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWA-PATHDGGAPLRGYQVECNRLG-STEWIRTAPPIVL 136
PP + + I SD + W+ P L+GY+V L EW
Sbjct: 882 PPENVRALSITSD----VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT 937
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R + L G+E Y +V A G S VL + + PP IK + +
Sbjct: 938 RERVELRGMEKFTNYSVQVLAYTQAGDG---VRSSVLYIQTKEDVPGPPAGIKAVPSSAS 994
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDE 252
V S +P Y IF S + A + E++ LF++I +
Sbjct: 995 --------SVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNR 1046
Query: 253 GE---IKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKP 308
G+ + A G + ++ +E A K + + + + L VG P
Sbjct: 1047 GQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1106
Query: 309 TPTIEWRHDGH----PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P ++W D P+ D I L + + K D G Y A N G DT
Sbjct: 1107 APAVKWTKDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAEDSGYYTCTATNTGGFDTI 1163
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA- 423
+ V PPD PR ++V++ S+TL W P D+GG + ++++Y W
Sbjct: 1164 IVNLLVQVPPDQPR-LTVSKTSASSITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDVF 1221
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I+S + + L L G+ YK ++ A++ G S SE + GR
Sbjct: 1222 ISSSERSFKLDSLKCGTWYKVKLAAKNSVG-SGRISEIIEAKTHGR 1266
Score = 60.5 bits (140), Expect = 3e-08
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 23/352 (6%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS--QEP 184
W + I+ + + E Q +L G+ + TVS +R + P
Sbjct: 419 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVP 478
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-----DDYEIFSSRRTAITTDEST 239
P F+ + + + + + G P P + W + + T
Sbjct: 479 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 538
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S LL +L D G C A+N G ++K+ P + + + +
Sbjct: 539 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI--TSHPNTTIAIKGHAKE 596
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPK------FSVLKIHSAKRSDRGEYQ 352
L T G+ I W G +I DR+ +I K S LK+ A R D +
Sbjct: 597 LNCTARGERPIIIRWEK-GDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFS 655
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
A N GED +TV PPDPP + + +S+ L W DG + + +EY
Sbjct: 656 CHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRW-TQRFDGNSIITGFDIEY 713
Query: 413 YR--TGWNV--WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
W+ + I+ + DL S Y R+ + + G S PS E
Sbjct: 714 KNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKE 765
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/196 (28%), Positives = 79/196 (40%), Gaps = 15/196 (7%)
Query: 190 RLEDV-TALE--NDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
R EDV T+L ND ++ T G P P I W KD + + R T T L
Sbjct: 17 RPEDVGTSLYFVNDSLQLPCTAPGYPIPAIRWLKDGRPLPADSRW---TKRITG-LTISD 72
Query: 247 ILPSDEGEIKCTATNRGGHA-VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV 305
+ D G C TN G A T + ++ P++ + G I T+ L +
Sbjct: 73 LRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTG----IGSTVILSCALT 128
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G P TI W + ++ D+ I I ++L I SA++S G YQ A TA
Sbjct: 129 GSPEFTIRWYRNTELVLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATR--KAQTAQ 185
Query: 366 FLVTVTAPPDPPRNVS 381
+ PR VS
Sbjct: 186 DFAIIALEDGTPRIVS 201
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 15/177 (8%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG I W KD I S I + E S L + G C A+N
Sbjct: 407 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAAT 466
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH--------D 317
+ +L + P+ +DG+ + L ++ G P P + W+H
Sbjct: 467 VSRERQLIVRVPPRFVVQPNNQDGI---YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 523
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTAP 373
HP+ RI+ I P S+L I D G Y QA N +G D + + +TV P
Sbjct: 524 YHPVPLTGRIQ--ILPNSSLL-IRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 577
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G P TI W+++ + +I S LL S G +C AT + A
Sbjct: 128 TGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 186
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD---- 324
A + LE R + + ++ E L G P PT+ W D PI+ D
Sbjct: 187 FAIIALEDGTP-RIVSSFSEKVVNP-GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHR 244
Query: 325 -DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
++ +S S + + + D G Y+ A+N++G + V PP
Sbjct: 245 TNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 295
Score = 46.0 bits (104), Expect = 7e-04
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 210 GIPSPTIAWFKDDYEIF---SSRRTAITTDESTSVLLFHQILPS--DEGEIKCTATNRGG 264
G P PT+ W DD I S R T + T++ + P D G +CTA N G
Sbjct: 222 GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVG 281
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
A +AR+ + P +R R + + ++G P +I+W D ++ D
Sbjct: 282 SAEYQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 336
Query: 325 DRIEISITPKFSVLKIHSAKRS-DRGEY 351
+ ++ + LK+ ++ D GEY
Sbjct: 337 NHRQVVF--ENGTLKLTDVQKGMDEGEY 362
Score = 45.2 bits (102), Expect = 0.001
Identities = 42/197 (21%), Positives = 76/197 (38%), Gaps = 6/197 (3%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + P I+ + ++TA+ + G P +I W+KD + + R + E+
Sbjct: 288 RINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--EN 345
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
++ L DEGE C+ + +++++ P L P ++ I + +
Sbjct: 346 GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPA---SIGQLL 402
Query: 299 FLKTTIVGKPTPT-IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ + P I WR DG II+ + I S L+I S G A N
Sbjct: 403 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 462
Query: 358 IIGEDTAAFLVTVTAPP 374
+ + V PP
Sbjct: 463 AAATVSRERQLIVRVPP 479
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1a protein.
Length = 2053
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/406 (24%), Positives = 155/406 (38%), Gaps = 36/406 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWA-PATHDGGAPLRGYQVECNRLG-STEWIRTAPPIVL 136
PP + + I SD + W+ P L+GY+V L EW
Sbjct: 1093 PPENVRALSITSD----VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT 1148
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R + L G+E Y +V A G S VL + + PP IK + +
Sbjct: 1149 RERVELRGMEKFTNYSVQVLAYTQAGDG---VRSSVLYIQTKEDVPGPPAGIKAVPSSAS 1205
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDE 252
V S +P Y IF S + A + E++ LF++I +
Sbjct: 1206 --------SVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNR 1257
Query: 253 GE---IKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKP 308
G+ + A G + ++ +E A K + + + + L VG P
Sbjct: 1258 GQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1317
Query: 309 TPTIEWRHDGH----PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P ++W D P+ D I L + + K D G Y A N G DT
Sbjct: 1318 APAVKWTKDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAEDSGYYTCTATNTGGFDTI 1374
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA- 423
+ V PPD PR ++V++ S+TL W P D+GG + ++++Y W
Sbjct: 1375 IVNLLVQVPPDQPR-LTVSKTSASSITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDVF 1432
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I+S + + L L G+ YK ++ A++ G S SE + GR
Sbjct: 1433 ISSSERSFKLDSLKCGTWYKVKLAAKNSVG-SGRISEIIEAKTHGR 1477
Score = 60.5 bits (140), Expect = 3e-08
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 23/352 (6%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS--QEP 184
W + I+ + + E Q +L G+ + TVS +R + P
Sbjct: 630 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVP 689
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-----DDYEIFSSRRTAITTDEST 239
P F+ + + + + + G P P + W + + T
Sbjct: 690 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 749
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S LL +L D G C A+N G ++K+ P + + + +
Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI--TSHPNTTIAIKGHAKE 807
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPK------FSVLKIHSAKRSDRGEYQ 352
L T G+ I W G +I DR+ +I K S LK+ A R D +
Sbjct: 808 LNCTARGERPIIIRWEK-GDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFS 866
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
A N GED +TV PPDPP + + +S+ L W DG + + +EY
Sbjct: 867 CHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRW-TQRFDGNSIITGFDIEY 924
Query: 413 YR--TGWNV--WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
W+ + I+ + DL S Y R+ + + G S PS E
Sbjct: 925 KNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKE 976
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/181 (28%), Positives = 71/181 (39%), Gaps = 12/181 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
VE T SG P P I W KD + + R T T L + D G C TN
Sbjct: 243 VELPCTASGYPIPAIRWLKDGRPLPADSRW---TKRITG-LTISDLRTEDSGTYICEVTN 298
Query: 262 RGGHA-VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
G A T + ++ P++ + G I T+ L + G P TI W +
Sbjct: 299 TFGSAEATGILMVIDPLHVTLTPKKLKTG----IGSTVILSCALTGSPEFTIRWYRNTEL 354
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
++ D+ I I ++L I SA++S G YQ A TA + PR V
Sbjct: 355 VLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIV 411
Query: 381 S 381
S
Sbjct: 412 S 412
Score = 51.6 bits (118), Expect = 1e-05
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 15/177 (8%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG I W KD I S I + E S L + G C A+N
Sbjct: 618 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAAT 677
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH--------D 317
+ +L + P+ +DG+ + L ++ G P P + W+H
Sbjct: 678 VSRERQLIVRVPPRFVVQPNNQDGI---YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTAP 373
HP+ RI+ I P S+L I D G Y QA N +G D + + +TV P
Sbjct: 735 YHPVPLTGRIQ--ILPNSSLL-IRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 788
Score = 50.8 bits (116), Expect = 3e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G P TI W+++ + +I S LL S G +C AT + A
Sbjct: 339 TGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 397
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD---- 324
A + LE R + + ++ E L G P PT+ W D PI+ D
Sbjct: 398 FAIIALEDGTP-RIVSSFSEKVVNP-GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHR 455
Query: 325 -DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
++ +S S + + + D G Y+ A+N++G + V PP
Sbjct: 456 TNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 506
Score = 46.8 bits (106), Expect = 4e-04
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 210 GIPSPTIAWFKDDYEIF---SSRRTAITTDESTSVLLFHQILPS--DEGEIKCTATNRGG 264
G P PT+ W DD I S R T + T++ + P D G +CTA N G
Sbjct: 433 GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVG 492
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
A +AR+ + P +R R + + ++G P +I+W D ++ D
Sbjct: 493 SAEYQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 547
Query: 325 DRIEISITPKFSVLKIHSAKRS-DRGEY 351
+ ++ + LK+ ++ D GEY
Sbjct: 548 NHRQVVF--ENGTLKLTDVQKGMDEGEY 573
Score = 45.2 bits (102), Expect = 0.001
Identities = 42/197 (21%), Positives = 76/197 (38%), Gaps = 6/197 (3%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + P I+ + ++TA+ + G P +I W+KD + + R + E+
Sbjct: 499 RINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--EN 556
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
++ L DEGE C+ + +++++ P L P ++ I + +
Sbjct: 557 GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPA---SIGQLL 613
Query: 299 FLKTTIVGKPTPT-IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ + P I WR DG II+ + I S L+I S G A N
Sbjct: 614 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 673
Query: 358 IIGEDTAAFLVTVTAPP 374
+ + V PP
Sbjct: 674 AAATVSRERQLIVRVPP 690
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
T+ L T G P P I W DG P+ D R T + + L I + D G Y +
Sbjct: 242 TVELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVT 297
Query: 357 NIIGEDTAAFLVTVTAP 373
N G A ++ V P
Sbjct: 298 NTFGSAEATGILMVIDP 314
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 8/198 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q P F +D +E V+F G P P IAW K ++ RR + S+
Sbjct: 447 QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVL---SSGT 503
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D+G+ +C A N G A L ++ + D + E+ + L
Sbjct: 504 LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTV-EVGANVQLP 562
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ G+P P I W DG + + IS P+ L I+ +D G Y+ A+N IG
Sbjct: 563 CSSQGEPEPAITWNKDGVQVTESGKFHIS--PE-GFLTINDVGPADAGRYECVARNTIGS 619
Query: 362 DTAAFLVTVTAPPDPPRN 379
+ + +++V PD RN
Sbjct: 620 ASVSMVLSVNV-PDVSRN 636
Score = 66.9 bits (156), Expect = 4e-10
Identities = 55/223 (24%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV--- 241
P F+ + ++ L + V + +G P P I+W + D RT + D ++
Sbjct: 359 PTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGD-------RTPLPVDPRVNITPS 411
Query: 242 --LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L ++ D GE C+ATN A + ++A P+ Q D ++ E +T+
Sbjct: 412 GGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQ--DRVVIE-GQTVD 468
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ G P P I W G + D R + L+I D+G+Y+ QA NII
Sbjct: 469 FQCEAKGNPPPVIAWTKGGSQLSVDRR---HLVLSSGTLRISGVALHDQGQYECQAVNII 525
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGG 402
G +TV P P S+ V + + P G
Sbjct: 526 GSQKVVAHLTV-QPRVTPVFASIPSDTTVEVGANVQLPCSSQG 567
Score = 62.9 bits (146), Expect = 6e-09
Identities = 56/209 (26%), Positives = 85/209 (40%), Gaps = 14/209 (6%)
Query: 172 VLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
V T++ + + E P +D + V F G P P I W +++ E+ +
Sbjct: 250 VATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDS 309
Query: 232 AIT-TDESTSVLLFHQILPSDEGEIKCTATNRGGHA----VTKARLCLEAAPKLRYPRQY 286
+ D+ T L+ +D+G +C A N G VT A P Q
Sbjct: 310 RLNLLDDGT--LMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQN 367
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEW-RHDGHPIITDDRIEISITPKFSVLKIHSAKR 345
+ L + E++ L+ + G P P I W R D P+ D R ++ITP L I + +
Sbjct: 368 TEVL---VGESVTLECSATGHPPPRISWTRGDRTPLPVDPR--VNITPS-GGLYIQNVVQ 421
Query: 346 SDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
D GEY A N I A + V A P
Sbjct: 422 GDSGEYACSATNNIDSVHATAFIIVQALP 450
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/406 (24%), Positives = 155/406 (38%), Gaps = 36/406 (8%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWA-PATHDGGAPLRGYQVECNRLG-STEWIRTAPPIVL 136
PP + + I SD + W+ P L+GY+V L EW
Sbjct: 1132 PPENVRALSITSD----VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTT 1187
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
R + L G+E Y +V A G S VL + + PP IK + +
Sbjct: 1188 RERVELRGMEKFTNYSVQVLAYTQAGDG---VRSSVLYIQTKEDVPGPPAGIKAVPSSAS 1244
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDE 252
V S +P Y IF S + A + E++ LF++I +
Sbjct: 1245 --------SVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNR 1296
Query: 253 GE---IKCTATNRGGHAVTKARLCLEAAPKLRYPR-QYEDGLLYEINETIFLKTTIVGKP 308
G+ + A G + ++ +E A K + + + + L VG P
Sbjct: 1297 GQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDP 1356
Query: 309 TPTIEWRHDGH----PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P ++W D P+ D I L + + K D G Y A N G DT
Sbjct: 1357 APAVKWTKDSEDSAIPVSMDGHRLIHTN---GTLLLRAVKAEDSGYYTCTATNTGGFDTI 1413
Query: 365 AFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA- 423
+ V PPD PR ++V++ S+TL W P D+GG + ++++Y W
Sbjct: 1414 IVNLLVQVPPDQPR-LTVSKTSASSITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDVF 1471
Query: 424 ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGR 469
I+S + + L L G+ YK ++ A++ G S SE + GR
Sbjct: 1472 ISSSERSFKLDSLKCGTWYKVKLAAKNSVG-SGRISEIIEAKTHGR 1516
Score = 59.7 bits (138), Expect = 6e-08
Identities = 78/352 (22%), Positives = 126/352 (35%), Gaps = 23/352 (6%)
Query: 127 WIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRAS--QEP 184
W + I+ + + E Q +L G+ + TVS +R + P
Sbjct: 669 WRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVP 728
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK-----DDYEIFSSRRTAITTDEST 239
P F+ + + + + + G P P + W + + T
Sbjct: 729 PRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPN 788
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
S LL +L D G C A+N G ++K+ P + + + +
Sbjct: 789 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMI--TSHPNTTIAIKGHAKE 846
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPK------FSVLKIHSAKRSDRGEYQ 352
L T G+ I W G +I DR+ +I K S LK+ A R D +
Sbjct: 847 LNCTARGERPIIIRWEK-GDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFS 905
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY 412
A N GED +TV PPDPP + + +S+ L W DG + + +EY
Sbjct: 906 CHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRW-TQRFDGNSIITGFDIEY 963
Query: 413 YR--TGWNV--WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSE 460
W+ + I+ + DL S Y R+ + + G S PS E
Sbjct: 964 KNKSDSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKE 1015
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/181 (28%), Positives = 71/181 (39%), Gaps = 12/181 (6%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
VE T SG P P I W KD + + R T T L + D G C TN
Sbjct: 282 VELPCTASGYPIPAIRWLKDGRPLPADSRW---TKRITG-LTISDLRTEDSGTYICEVTN 337
Query: 262 RGGHA-VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
G A T + ++ P++ + G I T+ L + G P TI W +
Sbjct: 338 TFGSAEATGILMVIDPLHVTLTPKKLKTG----IGSTVILSCALTGSPEFTIRWYRNTEL 393
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
++ D+ I I ++L I SA++S G YQ A TA + PR V
Sbjct: 394 VLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATR--KAQTAQDFAIIALEDGTPRIV 450
Query: 381 S 381
S
Sbjct: 451 S 451
Score = 52.4 bits (120), Expect = 8e-06
Identities = 47/177 (26%), Positives = 68/177 (38%), Gaps = 15/177 (8%)
Query: 206 VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
V SG I W KD I S I + E S L + G C A+N
Sbjct: 657 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT 716
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH--------D 317
+ +L + P+ +DG+ + L ++ G P P + W+H
Sbjct: 717 VSRERQLIVRVPPRFVVQPNNQDGI---YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 773
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTAP 373
HP+ RI+ I P S+L I D G Y QA N +G D + + +TV P
Sbjct: 774 YHPVPLTGRIQ--ILPNSSLL-IRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 827
Score = 50.0 bits (114), Expect = 4e-05
Identities = 41/171 (23%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+G P TI W+++ + +I S LL S G +C AT + A
Sbjct: 378 TGSPEFTIRWYRNTELVLPDEAISIR-GLSNETLLITSAQKSHSGAYQCFATRKAQTAQD 436
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD---- 324
A + LE R + + ++ E L G P PT+ W D PI+ D
Sbjct: 437 FAIIALEDGTP-RIVSSFSEKVVNP-GEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHR 494
Query: 325 -DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
++ +S S + + + D G Y+ A+N++G + V PP
Sbjct: 495 TNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPP 545
Score = 49.2 bits (112), Expect = 8e-05
Identities = 43/197 (21%), Positives = 77/197 (39%), Gaps = 6/197 (3%)
Query: 179 RASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES 238
R + P I+ + ++TA+ + G P +I W+KD + + R + E+
Sbjct: 538 RINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVF--EN 595
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
++ L DEGE C+ + +++++ P L P ++ I + +
Sbjct: 596 GTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPA---SIGQLL 652
Query: 299 FLKTTIVGKPTPT-IEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
++ + P I WR DG II+ + I S L+I S G Y A N
Sbjct: 653 YIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASN 712
Query: 358 IIGEDTAAFLVTVTAPP 374
+ + V PP
Sbjct: 713 AAATVSRERQLIVRVPP 729
Score = 46.0 bits (104), Expect = 7e-04
Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 13/148 (8%)
Query: 210 GIPSPTIAWFKDDYEIF---SSRRTAITTDESTSVLLFHQILPS--DEGEIKCTATNRGG 264
G P PT+ W DD I S R T + T++ + P D G +CTA N G
Sbjct: 472 GAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVG 531
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
A +AR+ + P +R R + + ++G P +I+W D ++ D
Sbjct: 532 SAEYQARINVRGPPSIRAMR----NITAVAGRDTLINCRVIGYPYYSIKWYKDA-LLLPD 586
Query: 325 DRIEISITPKFSVLKIHSAKRS-DRGEY 351
+ ++ + LK+ ++ D GEY
Sbjct: 587 NHRQVVF--ENGTLKLTDVQKGMDEGEY 612
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
T+ L T G P P I W DG P+ D R T + + L I + D G Y +
Sbjct: 281 TVELPCTASGYPIPAIRWLKDGRPLPADSR----WTKRITGLTISDLRTEDSGTYICEVT 336
Query: 357 NIIGEDTAAFLVTVTAP 373
N G A ++ V P
Sbjct: 337 NTFGSAEATGILMVIDP 353
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 70.1 bits (164), Expect = 4e-11
Identities = 70/262 (26%), Positives = 110/262 (41%), Gaps = 21/262 (8%)
Query: 209 SGIPSPTIAWFKDDYEIFSSR---RTAITTDESTSV---LLFHQILPSDEGEIKCTATNR 262
SG P P I WFKD + +S R T + L Q SD+G+ +C ATN
Sbjct: 126 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNS 185
Query: 263 GGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHD 317
G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 186 AGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLG 245
Query: 318 GHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPP 377
+ +D + I +VL+++ ++S Y A + +G A +TV A P PP
Sbjct: 246 AEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALPKPP 299
Query: 378 RNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTLFDL 436
VT S+TL W+ + V YI+++ K I T ++ L
Sbjct: 300 GTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGL 356
Query: 437 IEGSEYKFRIKAESPYGMSAPS 458
S+Y+FR+ A + G PS
Sbjct: 357 SPYSDYEFRVVAVNNIGRGPPS 378
Score = 53.6 bits (123), Expect = 4e-06
Identities = 49/188 (26%), Positives = 77/188 (40%), Gaps = 16/188 (8%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQ 246
F + D T + F +G P P I W K ++ + R I D+ + +L Q
Sbjct: 2 FTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQ 61
Query: 247 IL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLYEINETI 298
L P DE +C A+N G RL + ++ PR + + G + E T
Sbjct: 62 PLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVVERTRTA 119
Query: 299 FLKTTIVGKPTPTIEWRHDGHPIITDD------RIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ G P P I W D P+ T + ++ TP L+I ++ SD+G+Y+
Sbjct: 120 TMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYE 179
Query: 353 IQAKNIIG 360
A N G
Sbjct: 180 CVATNSAG 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 482 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 537
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 538 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 574
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 296 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 348
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 349 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 394
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 161 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 219
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 220 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 273
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 274 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 328
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 329 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 385
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 386 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 444
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 445 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 494
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 69.7 bits (163), Expect = 5e-11
Identities = 72/292 (24%), Positives = 116/292 (39%), Gaps = 18/292 (6%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG P P I WFKD + S + L +D+G+ +C ATN G +
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ PR + +EI + + VG P P ++W + +D
Sbjct: 219 SPANLYVRVRRVA-PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD 277
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
+ + +VL++ K D Y A + +G A +TV + P P VT
Sbjct: 278 MPVGR----NVLELTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 331
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
S+T+ W+ D V Y++EY + G + IT+ T ++ L SEY+
Sbjct: 332 ATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRYSIGGLSPNSEYE 386
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
+ A + G P SES R +A V+AR+++ EEP
Sbjct: 387 IWVSAVNSIG-QGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEP 437
Score = 66.5 bits (155), Expect = 5e-10
Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 6/187 (3%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A++EPP FIK +D + F +G P P + W K ++ S R I DES
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 240 SVLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPR--QYEDGLLYE 293
+L Q L P DE +C A N G A+L + +L +P + E
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
T + G P P I W D P+ + L+I S++ +D+G+Y+
Sbjct: 148 RTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYEC 207
Query: 354 QAKNIIG 360
A N G
Sbjct: 208 VATNSAG 214
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 512 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 568
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 569 EDLKPNTEYAFRLAARSPQGLGA 591
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PRNV ++ + WE P +
Sbjct: 380 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVE 439
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 440 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 498
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 499 LSDPIQVKTQQGVPGQPMNL 518
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 69.7 bits (163), Expect = 5e-11
Identities = 71/265 (26%), Positives = 111/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV A P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKALP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 32/109 (29%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PPG P ++++ +ITL W + P+ Y ++ S E + +
Sbjct: 323 PKPPGTP----VVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVAT 375
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 376 TRYSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 34.3 bits (75), Expect = 2.4
Identities = 70/350 (20%), Positives = 132/350 (37%), Gaps = 29/350 (8%)
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
+R L + E + ++ A N G + YS +++ + PP F +
Sbjct: 188 IRGALQIEQSEESDQGKYECVATNSAG-TRYSAPANLYVRELREVRRVPPRFSIPPTNHE 246
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ V G P P + W ++ I +VL + + S
Sbjct: 247 IMPGGSVNITCVAVGSPMPYVKWMLGAEDLTPEDDMPI----GRNVLELNDVRQS--ANY 300
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWR 315
C A + G A++ ++A PK ++ E T T G P P +
Sbjct: 301 TCVAMSTLGVIEAIAQITVKALPK-----PPGTPVVTESTATSITLTWDSGNPEPVSYYI 355
Query: 316 HDGHPIITDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF-LVTVT 371
P +++ I+ T ++SV + + SD E+++ A N IG + ++T T
Sbjct: 356 IQHKPKNSEELYKEIDGVATTRYSVAGL--SPYSDY-EFRVVAVNNIGRGPPSEPVLTQT 412
Query: 372 ---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW---NVWLKAIT 425
AP PR+V ++ + W+ P + G ++ Y V Y N W+K
Sbjct: 413 SEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNV 471
Query: 426 SRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVR---IPGRAID 472
+ T+ +L+ Y ++ A + G SS+ + +PG+ ++
Sbjct: 472 ADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLN 521
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 8/183 (4%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G P PP +++ S + +TL WA DGG L GY+VE + +W R +
Sbjct: 92 GLPDPPEDAEVVARSS----HTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQW-RLCHEL 146
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDV 194
V PE V+ GL P Y+FRVAA+ VG L + ++ P V
Sbjct: 147 VPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPKPVPPQPSAPESRQV 206
Query: 195 TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
A E+ +E V + + W K I R + + +L+ D+GE
Sbjct: 207 AAGEDVSLELEVV---AEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGE 263
Query: 255 IKC 257
C
Sbjct: 264 YHC 266
Score = 55.6 bits (128), Expect = 9e-07
Identities = 46/175 (26%), Positives = 69/175 (39%), Gaps = 10/175 (5%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQ 354
+ F T P W +G + DD ++ L + SA+ GE
Sbjct: 19 QACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFA 78
Query: 355 AKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
++ + A+ +TV PDPP + V + +VTL W P DGG + Y VE
Sbjct: 79 CRDAV----ASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKE 134
Query: 415 --TG-WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
TG W + + + + V L G Y+FR+ A P G P VR+
Sbjct: 135 GATGQWRLCHELVPGPECVVD--GLAPGETYRFRVAAVGPVGAGEPVHLPQTVRL 187
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S PVF+ L++ + V F +G P P++ WFKD + I D+
Sbjct: 693 SDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG 752
Query: 241 -VLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ ++P+D G +C A N G + TKA L
Sbjct: 753 HQLIITAVVPADMGVYRCLAENSMGVSSTKAEL 785
Score = 44.4 bits (100), Expect = 0.002
Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 16/156 (10%)
Query: 174 TVSSDRASQEPPVFIKRLEDVTALENDKV-EFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
T S+ Q P V ++ L D+ ++ +F + G P+P + WFKD + +S
Sbjct: 822 TESTTDEGQLPQV-VEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIR 880
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL------EAAP------KL 280
+T + L + D G+ +N G A + ARL + E P +L
Sbjct: 881 MTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQL 940
Query: 281 RYPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEW 314
PR E ++ + +I + G+P PT+ W
Sbjct: 941 VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHW 976
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/73 (27%), Positives = 32/73 (43%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ G P P + W DG P+ I ++ L+I S R D G+Y N +G
Sbjct: 856 VKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAY 915
Query: 364 AAFLVTVTAPPDP 376
++ + V P +P
Sbjct: 916 SSARLLVRGPDEP 928
Score = 33.1 bits (72), Expect = 5.5
Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 6/95 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE---IFSSRRT---AITTDE 237
PP ++R + + F V G P PT+ W +++ E ++ T + +
Sbjct: 942 PPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSA 1001
Query: 238 STSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L+ + +G C A+N G A+ A L
Sbjct: 1002 QQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 1036
>AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS
protein.
Length = 475
Score = 69.7 bits (163), Expect = 5e-11
Identities = 72/292 (24%), Positives = 116/292 (39%), Gaps = 18/292 (6%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG P P I WFKD + S + L +D+G+ +C ATN G +
Sbjct: 33 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 92
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ PR + +EI + + VG P P ++W + +D
Sbjct: 93 SPANLYVRVRRVA-PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD 151
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
+ + +VL++ K D Y A + +G A +TV + P P VT
Sbjct: 152 MPVGR----NVLELTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 205
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
S+T+ W+ D V Y++EY + G + IT+ T ++ L SEY+
Sbjct: 206 ATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRYSIGGLSPNSEYE 260
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
+ A + G P SES R +A V+AR+++ EEP
Sbjct: 261 IWVSAVNSIG-QGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEP 311
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 386 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 442
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 443 EDLKPNTEYAFRLAARSPQGLGA 465
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PRNV ++ + WE P +
Sbjct: 254 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVE 313
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 314 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 372
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 373 LSDPIQVKTQQGVPGQPMNL 392
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 69.7 bits (163), Expect = 5e-11
Identities = 72/292 (24%), Positives = 116/292 (39%), Gaps = 18/292 (6%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG P P I WFKD + S + L +D+G+ +C ATN G +
Sbjct: 185 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 244
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ PR + +EI + + VG P P ++W + +D
Sbjct: 245 SPANLYVRVRRVA-PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD 303
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
+ + +VL++ K D Y A + +G A +TV + P P VT
Sbjct: 304 MPVGR----NVLELTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 357
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
S+T+ W+ D V Y++EY + G + IT+ T ++ L SEY+
Sbjct: 358 ATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRYSIGGLSPNSEYE 412
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
+ A + G P SES R +A V+AR+++ EEP
Sbjct: 413 IWVSAVNSIG-QGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEP 463
Score = 66.5 bits (155), Expect = 5e-10
Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 6/187 (3%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A++EPP FIK +D + F +G P P + W K ++ S R I DES
Sbjct: 54 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 113
Query: 240 SVLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPR--QYEDGLLYE 293
+L Q L P DE +C A N G A+L + +L +P + E
Sbjct: 114 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 173
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
T + G P P I W D P+ + L+I S++ +D+G+Y+
Sbjct: 174 RTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYEC 233
Query: 354 QAKNIIG 360
A N G
Sbjct: 234 VATNSAG 240
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 538 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 594
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 595 EDLKPNTEYAFRLAARSPQGLGA 617
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PRNV ++ + WE P +
Sbjct: 406 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVE 465
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 466 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 524
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 525 LSDPIQVKTQQGVPGQPMNL 544
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 69.3 bits (162), Expect = 7e-11
Identities = 73/303 (24%), Positives = 117/303 (38%), Gaps = 16/303 (5%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 446 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 505
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A + L ++ A + +Q E ++ + F
Sbjct: 506 IPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWI--VKQPEYAVVQRGSMVSFEC 561
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 562 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 617
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY----YRTG 416
+A+ +++V P+PP ++ +T Q+DKSV L W P DD + +I+EY ++ G
Sbjct: 618 SVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFIIEYEDAMHKPG 676
Query: 417 WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFL 476
++ +T L L Y FR+ A + G S PS S D +
Sbjct: 677 LWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPT 735
Query: 477 AVE 479
AVE
Sbjct: 736 AVE 738
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSG 210
+V +++++ + + LSD + + + PP F+ + L + + G
Sbjct: 231 KVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG 290
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
+P+P I W K+D + RT E T ++ + +D G +C A N G
Sbjct: 291 LPTPIIYWAKED-GMLPKNRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTI 347
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEI 329
+ ++AAP Y L+ E L G P P I W +G PI I D
Sbjct: 348 SVRVKAAP---YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 404
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
I +++ + +RS YQ A N G A V V A +PPR
Sbjct: 405 KIDGD-TIIFSNVQERSS-AVYQCNASNEYGYLLANAFVNVLA--EPPR 449
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/303 (24%), Positives = 115/303 (37%), Gaps = 16/303 (5%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 446 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 505
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A K + LE +Q E ++ + F
Sbjct: 506 IPVAQ--KDSTGTYTCVARNKLGMA--KNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 561
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 562 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 617
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY----YRTG 416
+A+ +++V P+PP ++ +T Q+DKSV L W P DD + +I+EY ++ G
Sbjct: 618 SVSASAVLSVVDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFIIEYEDAMHKPG 676
Query: 417 WNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFL 476
++ +T L L Y FR+ A + G S PS S D +
Sbjct: 677 LWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPT 735
Query: 477 AVE 479
AVE
Sbjct: 736 AVE 738
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSG 210
+V +++++ + + LSD + + + PP F+ + L + + G
Sbjct: 231 KVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG 290
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
+P+P I W K+D + RT E T ++ + +D G +C A N G
Sbjct: 291 LPTPIIYWAKED-GMLPKNRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTI 347
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEI 329
+ ++AAP Y L+ E L G P P I W +G PI I D
Sbjct: 348 SVRVKAAP---YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 404
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
I +++ + +RS YQ A N G A V V A +PPR
Sbjct: 405 KIDGD-TIIFSNVQERSS-AVYQCNASNEYGYLLANAFVNVLA--EPPR 449
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 936 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPTN 993
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 994 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1028
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 68.5 bits (160), Expect = 1e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 11/216 (5%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS-- 227
+D L V+ S P + +R +++T VE G PSPT+ W + + S
Sbjct: 1731 TDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSES 1790
Query: 228 ---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
SR+ +T D L+ H + D G KC A+N GG ++ + AAP +
Sbjct: 1791 SQGSRQAVVTVD---GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPV-ILE 1846
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS--VLKIHS 342
Q ++ E++ L T G P P++ W + + S FS L I +
Sbjct: 1847 QRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRN 1906
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
SDRG Y+ A + G + ++T+ PR
Sbjct: 1907 LASSDRGTYECIATSSTGSERRVVMLTMEERVTSPR 1942
Score = 58.8 bits (136), Expect = 1e-07
Identities = 51/193 (26%), Positives = 81/193 (41%), Gaps = 12/193 (6%)
Query: 209 SGIPSPTIAWFKDDYEIF--------SSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
SG P P I+W D + S RT T + L F+++ ++EG+ C A
Sbjct: 2063 SGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQ 2122
Query: 261 NRGGHAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G K L + AAP++R + + + +T L + G P P I W +
Sbjct: 2123 NTLGKDEMKVHLTVITAAPRIRQSNKTNKRI--KAGDTAVLDCEVTGDPKPKIFWLLPSN 2180
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
+I+ + S L I+ K D GEY A+N G+DT + + V + P
Sbjct: 2181 DMISFSIDRYTFHANGS-LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLING 2239
Query: 380 VSVTRQVDKSVTL 392
+ R V K+ +
Sbjct: 2240 LYTNRTVIKATAV 2252
Score = 58.0 bits (134), Expect = 2e-07
Identities = 53/224 (23%), Positives = 83/224 (37%), Gaps = 14/224 (6%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++R AA N VG Y E +L + Q+P + V + + + H GI
Sbjct: 2408 KYRCAARNKVG---YIEKLVILEIG-----QKPVILTYAPGTVKGISGESLSLHCVSDGI 2459
Query: 212 PSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W Y + + L+ + D G C A N GH +
Sbjct: 2460 PKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 2519
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
+ + A P R + ++ L +G P P I W H +++ E +
Sbjct: 2520 PVMIVAYPP-RITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERT 2578
Query: 331 ITPKF----SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ L I + + SD G Y+ AKN +G D AA + V
Sbjct: 2579 HGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 3/169 (1%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
TA+ + K F G PSP + W D+ + + + T L + SD
Sbjct: 2250 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 2309
Query: 254 EIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ C A N GG +V +L LE + + + + ++ ++ ++ L ++ G P P I
Sbjct: 2310 DFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEI 2369
Query: 313 EW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
W +G + + I R D G+Y+ A+N +G
Sbjct: 2370 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 2418
Score = 50.8 bits (116), Expect = 3e-05
Identities = 47/200 (23%), Positives = 81/200 (40%), Gaps = 12/200 (6%)
Query: 184 PPVFIK-RLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDE-STS 240
PPV ++ R + + + ++ T G P P++ W D E+ + T S
Sbjct: 1841 PPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNG 1900
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE---AAPKLRYPRQYEDGLLYEINET 297
L + SD G +C AT+ G L +E +P++ Q + + +
Sbjct: 1901 TLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNF--GDK 1958
Query: 298 IFLKTTIVGKPTPTIEWRHDGHPIITDD-RIE--ISITPKFSVLKIHSAKRSDRGEYQIQ 354
+ L + G+P P I WR ++ R+ I + P S+ I S D G Y
Sbjct: 1959 LLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLF-IGSVTEKDSGVYLCV 2017
Query: 355 AKNIIGEDTAAFLVTVTAPP 374
A+N +G+D V++ P
Sbjct: 2018 ARNKMGDDLILMHVSLRLKP 2037
Score = 45.6 bits (103), Expect = 0.001
Identities = 52/203 (25%), Positives = 81/203 (39%), Gaps = 16/203 (7%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFHQILPS 250
E + A + + G P P I W + FS+ + S + +
Sbjct: 2345 EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 2404
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPT 309
D G+ +C A N+ G+ L + P + Y G + I+ E++ L G P
Sbjct: 2405 DAGKYRCAARNKVGYIEKLVILEIGQKPVIL---TYAPGTVKGISGESLSLHCVSDGIPK 2461
Query: 310 PTIEWRHDGHPIITDDRIEIS---ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P I+W ++ DR +I+ I L I A DRG Y +A+N +G
Sbjct: 2462 PNIKWTMPSGYVV--DRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 2519
Query: 367 LVTVTA-PP----DPPRNVSVTR 384
V + A PP PPR++ VTR
Sbjct: 2520 PVMIVAYPPRITNRPPRSI-VTR 2541
Score = 39.5 bits (88), Expect = 0.063
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE---ISITPKFSVLKIHSAKRSDRGEY 351
N FL VG P PTI W + R + + + P L I + DRG+Y
Sbjct: 1663 NSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN-GTLSIQRVEIQDRGQY 1721
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPDPPR 378
A N+ G D VT++ PPR
Sbjct: 1722 LCSASNLFGTD--HLHVTLSVVSYPPR 1746
Score = 33.1 bits (72), Expect = 5.5
Identities = 49/228 (21%), Positives = 86/228 (37%), Gaps = 11/228 (4%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDD 222
SNY + +D+LT + + T + ++ +GIP +I+W +
Sbjct: 554 SNYDD-ADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVIPGN 612
Query: 223 YEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGG--HAVTKARLCLEAAPKL 280
++ S R + T +L Q+ P D+G +C A N G + + + ++ L
Sbjct: 613 NVLYQSSRDKKVLNNGTLRIL--QVTPKDQGYYRCVAANPSGVDFLIFQVSVKMKGQRPL 670
Query: 281 RYPRQYEDGLLYEINETIFLKTTIVG--KPTPTIEWRHDGHPIITDDRIEI-SITPKFSV 337
+ + E L E N LK + + +E H T R +T +
Sbjct: 671 EHDGETEGSGLDESNPIAHLKEPPGAQLRTSALMEAEVGKHTSSTSKRHNYRELTLQRRG 730
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDTAAFL--VTVTAPPDPPRNVSVT 383
H R +R + A+ I + AA L A PD N +V+
Sbjct: 731 DSTHRRFRENRRHFPPSARRIDPQHWAALLEKAKKNAMPDKRENTTVS 778
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 68.5 bits (160), Expect = 1e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 11/216 (5%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS-- 227
+D L V+ S P + +R +++T VE G PSPT+ W + + S
Sbjct: 358 TDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSES 417
Query: 228 ---SRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
SR+ +T D L+ H + D G KC A+N GG ++ + AAP +
Sbjct: 418 SQGSRQAVVTVD---GTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPV-ILE 473
Query: 285 QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS--VLKIHS 342
Q ++ E++ L T G P P++ W + + S FS L I +
Sbjct: 474 QRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRN 533
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
SDRG Y+ A + G + ++T+ PR
Sbjct: 534 LASSDRGTYECIATSSTGSERRVVMLTMEERVTSPR 569
Score = 39.9 bits (89), Expect = 0.048
Identities = 32/138 (23%), Positives = 56/138 (40%), Gaps = 8/138 (5%)
Query: 184 PPVFIK-RLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDE-STS 240
PPV ++ R + + + ++ T G P P++ W D E+ + T S
Sbjct: 468 PPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNG 527
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE---AAPKLRYPRQYEDGLLYEINET 297
L + SD G +C AT+ G L +E +P++ Q + + +
Sbjct: 528 TLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNF--GDK 585
Query: 298 IFLKTTIVGKPTPTIEWR 315
+ L + G+P P I WR
Sbjct: 586 LLLNCSATGEPKPQIMWR 603
Score = 39.5 bits (88), Expect = 0.063
Identities = 27/87 (31%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE---ISITPKFSVLKIHSAKRSDRGEY 351
N FL VG P PTI W + R + + + P L I + DRG+Y
Sbjct: 290 NSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN-GTLSIQRVEIQDRGQY 348
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPDPPR 378
A N+ G D VT++ PPR
Sbjct: 349 LCSASNLFGTD--HLHVTLSVVSYPPR 373
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 68.1 bits (159), Expect = 2e-10
Identities = 81/304 (26%), Positives = 127/304 (41%), Gaps = 29/304 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSS------RRTAITTDESTSVLLFHQILPS---DEGEIKCTA 259
SG P P I WFKD + S ++ T EST + QI S D+G+ +C A
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYECVA 218
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR + +EI + + VG P P ++W
Sbjct: 219 TNSAGVRYSSPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKW 278
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + + +VL++ K D Y A + +G A +TV + P
Sbjct: 279 MQGAEDLTPEDDMPVGR----NVLELTDVK--DSANYTCVAMSSLGVIEAVAQITVKSLP 332
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNV 431
P VT S+T+ W+ D V Y++EY + G + IT+ T
Sbjct: 333 KAPGTPMVTENTATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRY 387
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTRED 491
++ L SEY+ + A + G P SES R +A V+AR+++
Sbjct: 388 SIGGLSPNSEYEIWVSAVNSIG-QGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQ 446
Query: 492 GEEP 495
EEP
Sbjct: 447 WEEP 450
Score = 67.3 bits (157), Expect = 3e-10
Identities = 56/196 (28%), Positives = 83/196 (42%), Gaps = 15/196 (7%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A++EPP FIK +D + F +G P P + W K ++ S R I DES
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 240 SVLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPR--QYEDGLLYE 293
+L Q L P DE +C A N G A+L + +L +P + E
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPI---ITDDRIE------ISITPKFSVLKIHSAK 344
T + G P P I W D P+ ++ RI+ TP L+I S++
Sbjct: 148 RTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSE 207
Query: 345 RSDRGEYQIQAKNIIG 360
+D+G+Y+ A N G
Sbjct: 208 ETDQGKYECVATNSAG 223
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 525 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 581
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 582 EDLKPNTEYAFRLAARSPQGLGA 604
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PRNV ++ + WE P +
Sbjct: 393 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVE 452
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 453 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 511
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 512 LSDPIQVKTQQGVPGQPMNL 531
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 68.1 bits (159), Expect = 2e-10
Identities = 50/194 (25%), Positives = 76/194 (39%), Gaps = 4/194 (2%)
Query: 182 QEPPVFIK-RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q PP F + E V+ + + SG+P+PT+ W KD + SS + +
Sbjct: 34 QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR- 92
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ P+ G C A N A + + AP++R + + E + + L
Sbjct: 93 -LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLE-GQEVRL 150
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
G+P P + W DG P+ D + L + SD G Y A N G
Sbjct: 151 DCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAG 210
Query: 361 EDTAAFLVTVTAPP 374
ED V V PP
Sbjct: 211 EDARLHTVNVLVPP 224
Score = 65.7 bits (153), Expect = 8e-10
Identities = 48/168 (28%), Positives = 70/168 (41%), Gaps = 10/168 (5%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
++ G P P I W KD + R + + L H+ D G +C A N
Sbjct: 1133 IQLDCVVRGDPVPDIHWIKDGLPL---RGSHLRHQLQNGSLTIHRTERDDAGRYQCLAEN 1189
Query: 262 RGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI 321
G A L L++AP + Q + + + L+ G+PTPTIEW G P+
Sbjct: 1190 EMGVAKKVVILVLQSAPVFQVEPQ---DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPL 1246
Query: 322 ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLV 368
R+ T L + + + D G Y A N++G TA AFLV
Sbjct: 1247 RASRRLR---TLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLV 1291
Score = 64.1 bits (149), Expect = 3e-09
Identities = 66/235 (28%), Positives = 93/235 (39%), Gaps = 17/235 (7%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALEN 199
L+LT P QF N+VG ++ L V TV PP D T
Sbjct: 718 LLLTAPGPQDSAQFECVVSNEVGEAH--RLYQV-TV------HVPPTIADDQTDFTVTMM 768
Query: 200 DKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTA 259
V +GIP+PT++W K ++ +R + S L Q LP G C+A
Sbjct: 769 APVVLTCHSTGIPAPTVSWSKAGAQL-GARGSGYRVSPS-GALEIGQALPIHAGRYTCSA 826
Query: 260 TNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G A L ++A+P ++ P + E E + L G P PTI W+ +G
Sbjct: 827 RNSAGVAHKHVFLTVQASPVVK-PLPSVVRAVAE--EEVLLPCEASGIPRPTITWQKEGL 883
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ T + + P L+I A D G Y AKN G + V PP
Sbjct: 884 NVATG--VSTQVLPG-GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPP 935
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 18/198 (9%)
Query: 182 QEPPVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q PV +K L V A+ ++V SGIP PTI W K+ + + T +
Sbjct: 842 QASPV-VKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLR 900
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--- 297
+ P D G C A N G A+ K RL ++ P + E+G L +++ T
Sbjct: 901 IA---HASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI------ENG-LPDLSTTEGS 950
Query: 298 -IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
FL G P P I W DG P ++ + +I P +L + + + D G Y A+
Sbjct: 951 HAFLPCKARGSPEPNITWDKDGQP-VSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAE 1008
Query: 357 NIIGEDTAAFLVTVTAPP 374
N +G +T+ P
Sbjct: 1009 NAVGRARRRVHLTILVLP 1026
Score = 60.9 bits (141), Expect = 2e-08
Identities = 52/193 (26%), Positives = 73/193 (37%), Gaps = 9/193 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L D++ E G P P I W KD + S T + +
Sbjct: 932 QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGE 989
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
LL + D G CTA N G A + L + P + D L + + ++L+
Sbjct: 990 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPV--FTTLPGDRSL-RLGDRLWLR 1046
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G PTP I W + P+ +S S L+ + R D G Y A+N +G
Sbjct: 1047 CAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGR 1102
Query: 362 DTAAFLVTVTAPP 374
A V V P
Sbjct: 1103 TQAVSFVHVKEAP 1115
Score = 59.3 bits (137), Expect = 7e-08
Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 16/182 (8%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P P I W KD + + +T VL + D G C A + G
Sbjct: 432 GTPQPNITWHKDGQALTRLENNS----RATRVLRVENVQVRDAGLYTCLAESPAGAIEKS 487
Query: 270 ARLCLEAAPKLRYPR--QYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
R+ ++A P + PR ++ GL + L+ ++ +P P I W DG + D
Sbjct: 488 FRVRVQAPPNIVGPRGPRFVVGLA---PGQLVLECSVEAEPAPKITWHRDGIVLQEDAHT 544
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP----DPPR-NVSV 382
+ +F L++ + +D G+Y A+N G + AF V + P PP NVSV
Sbjct: 545 QFPERGRF--LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSV 602
Query: 383 TR 384
+
Sbjct: 603 NQ 604
Score = 56.4 bits (130), Expect = 5e-07
Identities = 42/152 (27%), Positives = 58/152 (38%), Gaps = 9/152 (5%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P+P I W +D + T E L + +D G+ CTA N G R
Sbjct: 525 PAPKITWHRDGIVLQEDAHTQFP--ERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 582
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI-EIS 330
+ + P +R + +N+T L G P P + WR D P+ D R
Sbjct: 583 VEIHTVPTIR---SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL--DPRSPRFE 637
Query: 331 ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
I P+ S L+I D G Y A N G D
Sbjct: 638 ILPEGS-LRIQPVLAQDAGHYLCLASNSAGSD 668
Score = 55.6 bits (128), Expect = 9e-07
Identities = 49/190 (25%), Positives = 77/190 (40%), Gaps = 10/190 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PVF D + D++ G P+P I W +D + ++ + S L
Sbjct: 1026 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 1081
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ D G C A NR G + + ++ AP L+ + L+ + +I L +
Sbjct: 1082 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ--GEAFSYLVEPVGGSIQLDCVV 1139
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-EDT 363
G P P I W DG P+ + + + L IH +R D G YQ A+N +G
Sbjct: 1140 RGDPVPDIHWIKDGLPL-RGSHLRHQL--QNGSLTIHRTERDDAGRYQCLAENEMGVAKK 1196
Query: 364 AAFLVTVTAP 373
LV +AP
Sbjct: 1197 VVILVLQSAP 1206
Score = 44.8 bits (101), Expect = 0.002
Identities = 44/185 (23%), Positives = 70/185 (37%), Gaps = 7/185 (3%)
Query: 209 SGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV 267
SG P P + W+KD ++ F ++ A S ++LL P D + +C +N G A
Sbjct: 685 SGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAP-GPQDSAQFECVVSNEVGEAH 743
Query: 268 TKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRI 327
++ + P + + + + L G P PT+ W G +
Sbjct: 744 RLYQVTVHVPPTI---ADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGS- 799
Query: 328 EISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVD 387
++P L+I A G Y A+N G +TV A P SV R V
Sbjct: 800 GYRVSPS-GALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 858
Query: 388 KSVTL 392
+ L
Sbjct: 859 EEEVL 863
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/91 (31%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PVF +D+T D V +G P+PTI W + + +SRR D S
Sbjct: 1203 QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS--- 1259
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
L + D G C A N G A +A L
Sbjct: 1260 LWLENVETGDAGTYDCVAHNLLGSATARAFL 1290
Score = 41.1 bits (92), Expect = 0.021
Identities = 28/130 (21%), Positives = 44/130 (33%)
Query: 197 LENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIK 256
LE +V G P P +AW KD + + L+ + SD G
Sbjct: 143 LEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYT 202
Query: 257 CTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
C A N G + + P ++ L+ E + + + G P + W
Sbjct: 203 CVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLK 262
Query: 317 DGHPIITDDR 326
DG P+ R
Sbjct: 263 DGLPLPLSQR 272
Score = 35.9 bits (79), Expect = 0.78
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP--DPPRNVSVTRQVDKSVTL 392
L+I A+ SD+G Y + N+ GE F +TV PP + P+ +V++ + L
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVL 57
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/159 (28%), Positives = 67/159 (42%), Gaps = 10/159 (6%)
Query: 209 SGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGH 265
+G P+P IAW KD D+ RR + D+ V + D G CTA N G
Sbjct: 13 TGHPNPQIAWQKDGGTDFPAARERRMHVMPDDD--VFFITDVKIDDAGVYSCTAQNSAGS 70
Query: 266 AVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDD 325
A L + P L P ED ++ + ET+ L+ G P P I W P+ +
Sbjct: 71 ISANATLTVLETPSLVVP--LEDRVV-SVGETVALQCKATGNPPPRITWFKGDRPLSLTE 127
Query: 326 RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
R +TP +L + + D G Y + N +G + A
Sbjct: 128 RHH--LTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERA 164
Score = 40.7 bits (91), Expect = 0.027
Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 2/82 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P + LED + V +G P P I WFK D + + R +T D +L
Sbjct: 81 ETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPD--NQLL 138
Query: 243 LFHQILPSDEGEIKCTATNRGG 264
+ ++ D G C +N G
Sbjct: 139 VVQNVVAEDAGRYTCEMSNTLG 160
Score = 35.1 bits (77), Expect = 1.4
Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 5/78 (6%)
Query: 300 LKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
L+ G P P I W+ DG P + R+ + P V I K D G Y A+
Sbjct: 8 LECAATGHPNPQIAWQKDGGTDFPAARERRMHVM--PDDDVFFITDVKIDDAGVYSCTAQ 65
Query: 357 NIIGEDTAAFLVTVTAPP 374
N G +A +TV P
Sbjct: 66 NSAGSISANATLTVLETP 83
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 67.7 bits (158), Expect = 2e-10
Identities = 70/265 (26%), Positives = 110/265 (41%), Gaps = 24/265 (9%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTA-ITTDESTSV--------LLFHQILPSDEGEIKCTA 259
SG P P I WFKD + +S I S S+ L Q SD+G+ +C A
Sbjct: 150 SGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVA 209
Query: 260 TNRGGHAVTK-ARLCLEAAPKLRY--PRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW 314
TN G + A L + ++R PR +EI ++ + VG P P ++W
Sbjct: 210 TNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKW 269
Query: 315 RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ +D + I +VL+++ ++S Y A + +G A +TV P
Sbjct: 270 MLGAEDLTPEDDMPIGR----NVLELNDVRQS--ANYTCVAMSTLGVIEAIAQITVKPLP 323
Query: 375 DPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS-RKTNVTL 433
PP VT S+TL W+ + V YI+++ K I T ++
Sbjct: 324 KPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTRYSV 380
Query: 434 FDLIEGSEYKFRIKAESPYGMSAPS 458
L S+Y+FR+ A + G PS
Sbjct: 381 AGLSPYSDYEFRVVAVNNIGRGPPS 405
Score = 58.0 bits (134), Expect = 2e-07
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
++ PP F + D T + F +G P P I W K ++ + R I D+ +
Sbjct: 20 AETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSG 79
Query: 241 VLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQY---EDG---LLY 292
+L Q L P DE +C A+N G RL + ++ PR + + G +
Sbjct: 80 SVLRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQI--PRGFPTIDMGPQLKVV 137
Query: 293 EINETIFLKTTIVGKPTPTIEWRHDGHPIITDD---RIE------ISITPKFSVLKIHSA 343
E T + G P P I W D P+ T + RI+ I TP L+I +
Sbjct: 138 ERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQS 197
Query: 344 KRSDRGEYQIQAKNIIG 360
+ SD+G+Y+ A N G
Sbjct: 198 EESDQGKYECVATNSAG 214
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 367 LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS 426
++T T P P N + + S+ L W PP D + NY + Y+ G + + IT
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSD---TIANYEL-VYKDGEHGEEQRITI 564
Query: 427 RK-TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
T+ L L S Y FR+ A SP G+ A ++E S
Sbjct: 565 EPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEIS 601
Score = 43.2 bits (97), Expect = 0.005
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP 138
P KP P++++ +ITL W + P+ Y ++ S E + +
Sbjct: 321 PLPKPPGTPVVTESTATSITLTWDSGNPE---PVSYYIIQHKPKNSEELYKEIDGVATTR 377
Query: 139 ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
V GL P Y+FRV A+N++G SE VLT +S++A P
Sbjct: 378 YSV-AGLSPYSDYEFRVVAVNNIGRGPPSE--PVLTQTSEQAPSSAP 421
Score = 32.7 bits (71), Expect = 7.3
Identities = 30/133 (22%), Positives = 58/133 (43%), Gaps = 11/133 (8%)
Query: 350 EYQIQAKNIIGEDTAAF-LVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKV 405
E+++ A N IG + ++T T AP PR+V ++ + W+ P + G ++
Sbjct: 390 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNG-QI 448
Query: 406 GNYIVEYYRTGW---NVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
Y V Y N W+K + T+ +L+ Y ++ A + G SS+
Sbjct: 449 QGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508
Query: 463 PVR---IPGRAID 472
+ +PG+ ++
Sbjct: 509 VITQTGVPGQPLN 521
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 67.3 bits (157), Expect = 3e-10
Identities = 63/265 (23%), Positives = 102/265 (38%), Gaps = 18/265 (6%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P P W K + + R I+ D + ++ + SD G C ATN G A +
Sbjct: 107 PKPVYTWKKGRDILKENERITISEDGNLRII---NVTKSDAGSYTCIATNHFGTASSTGN 163
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI--EWRHDGHPIITD---DR 326
L ++ ++ P D + E+I L + + I W +GH I D D
Sbjct: 164 LVVKDPTRVMVPPSSMD---VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDH 220
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
E L I + + G+Y + + +AA + V PP PP V++
Sbjct: 221 FERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEIT 280
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW---NVWLKAITSRKTNVTLFDLIEGS 440
D + L W P D + Y+++ + GW + + I + T+ L
Sbjct: 281 DTTAQLSWR-PGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWV 339
Query: 441 EYKFRIKAESPYGMSAPSSESSPVR 465
EY+FR A + G+ PS S R
Sbjct: 340 EYEFRTVAANVIGIGEPSRPSEKRR 364
Score = 45.2 bits (102), Expect = 0.001
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 8/109 (7%)
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
+ E +F + G+P PT +W +G P++T DRI+I + L I SD G YQ
Sbjct: 1 MEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQI----EQGTLNITIVNLSDAGMYQC 56
Query: 354 QAKNIIGE-DTAAFLVTVTAPPDPPRNV--SVTR-QVDKSVTLDWEPPA 398
A+N G + A L + PD R + VT +V V ++ +P A
Sbjct: 57 LAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKA 105
Score = 39.5 bits (88), Expect = 0.063
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVL 136
PPG P+ + I + A L W P D +P+ Y ++ S W + T P ++
Sbjct: 267 PPGPPEAVTIDEITDTTA-QLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELID 324
Query: 137 RPELVLT--GLEPPHKYQFRVAALNDVGHSNYSELSD 171
T GL P +Y+FR A N +G S S+
Sbjct: 325 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSE 361
>BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein.
Length = 353
Score = 66.9 bits (156), Expect = 4e-10
Identities = 59/189 (31%), Positives = 85/189 (44%), Gaps = 14/189 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIE---ISITPKFSVLKIHSAKRSDRGEY 351
T + G P P I W D P+ ++ RI+ +P L+I S++ SD+G+Y
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKY 211
Query: 352 QIQAKNIIG 360
+ A N G
Sbjct: 212 ECVATNSAG 220
>BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein.
Length = 347
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
>AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 347
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
>AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 353
Score = 66.9 bits (156), Expect = 4e-10
Identities = 59/189 (31%), Positives = 85/189 (44%), Gaps = 14/189 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIE---ISITPKFSVLKIHSAKRSDRGEY 351
T + G P P I W D P+ ++ RI+ +P L+I S++ SD+G+Y
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKY 211
Query: 352 QIQAKNIIG 360
+ A N G
Sbjct: 212 ECVATNSAG 220
>AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 262
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 66.9 bits (156), Expect = 4e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 53 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 112
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 113 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 171
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 172 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 228
Query: 355 AKNIIG 360
A N G
Sbjct: 229 ATNSAG 234
Score = 33.1 bits (72), Expect = 5.5
Identities = 28/102 (27%), Positives = 45/102 (44%), Gaps = 10/102 (9%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEYYRT-----GWNVWLKAI 424
+ P PP+ V +V + W PPAD + Y V Y G +V + I
Sbjct: 363 STPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHV-VDGI 421
Query: 425 TSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
+ ++ L L + +EY+ ++A + G P ESSPV +
Sbjct: 422 SREHSSWDLVGLEKWTEYRVWVRAHTDVG---PGPESSPVLV 460
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 66.5 bits (155), Expect = 5e-10
Identities = 71/292 (24%), Positives = 116/292 (39%), Gaps = 17/292 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG P P I WFKD + S + L +D+G+ +C ATN G +
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ PR + +EI + + VG P P ++W + +D
Sbjct: 219 SPANLYVRVRRVA-PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD 277
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
+ + +VL++ K S + A + +G A +TV + P P VT
Sbjct: 278 MPVGR----NVLELTDVKDS-ANYHPCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 332
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
S+T+ W+ D V Y++EY + G + IT+ T ++ L SEY+
Sbjct: 333 ATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRYSIGGLSPNSEYE 387
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
+ A + G P SES R +A V+AR+++ EEP
Sbjct: 388 IWVSAVNSIG-QGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEP 438
Score = 66.1 bits (154), Expect = 6e-10
Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 6/187 (3%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A++EPP FIK +D + F +G P P + W K ++ S R I DES
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 240 SVLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPR--QYEDGLLYE 293
+L Q L P DE +C A N G A+L + +L +P + E
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
T + G P P I W D P+ + L+I S++ +D+G+Y+
Sbjct: 148 RTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYEC 207
Query: 354 QAKNIIG 360
A N G
Sbjct: 208 VATNSAG 214
Score = 38.3 bits (85), Expect = 0.15
Identities = 39/140 (27%), Positives = 59/140 (42%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PPRNV ++ + WE P +
Sbjct: 381 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVE 440
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 441 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 499
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 500 LSDPIQVKTQQGVPGQPMNL 519
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 513 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 569
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 570 EDLKPNTEYAFRLAARSPQGLGA 592
Score = 33.9 bits (74), Expect = 3.2
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PG P + +++ +IT+ W D P+ Y +E + S + +
Sbjct: 320 PKAPGTPMV----TENTATSITITWDSGNPD---PVSYYVIEY-KSKSQDGPYQIKEDIT 371
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y+ V+A+N +G SE V+T + ++A PP
Sbjct: 372 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSE--SVVTRTGEQAPARPP 418
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 66.5 bits (155), Expect = 5e-10
Identities = 71/292 (24%), Positives = 116/292 (39%), Gaps = 17/292 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG P P I WFKD + S + L +D+G+ +C ATN G +
Sbjct: 159 SGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS 218
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
++ PR + +EI + + VG P P ++W + +D
Sbjct: 219 SPANLYVRVRRVA-PRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDLTPEDD 277
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
+ + +VL++ K S + A + +G A +TV + P P VT
Sbjct: 278 MPVGR----NVLELTDVKDS-ANYHPCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTENT 332
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWLKAITSRKTNVTLFDLIEGSEYK 443
S+T+ W+ D V Y++EY + G + IT+ T ++ L SEY+
Sbjct: 333 ATSITITWDSGNPD---PVSYYVIEYKSKSQDGPYQIKEDITT--TRYSIGGLSPNSEYE 387
Query: 444 FRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIINEALTREDGEEP 495
+ A + G P SES R +A V+AR+++ EEP
Sbjct: 388 IWVSAVNSIG-QGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEP 438
Score = 66.1 bits (154), Expect = 6e-10
Identities = 52/187 (27%), Positives = 77/187 (41%), Gaps = 6/187 (3%)
Query: 180 ASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST 239
A++EPP FIK +D + F +G P P + W K ++ S R I DES
Sbjct: 28 AAEEPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESA 87
Query: 240 SVLLFHQIL--PSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPR--QYEDGLLYE 293
+L Q L P DE +C A N G A+L + +L +P + E
Sbjct: 88 GAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVE 147
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
T + G P P I W D P+ + L+I S++ +D+G+Y+
Sbjct: 148 RTRTATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYEC 207
Query: 354 QAKNIIG 360
A N G
Sbjct: 208 VATNSAG 214
Score = 38.3 bits (85), Expect = 0.15
Identities = 39/140 (27%), Positives = 59/140 (42%), Gaps = 13/140 (9%)
Query: 346 SDRGEYQI--QAKNIIGEDTAA-FLVTVT---APPDPPRNVSVTRQVDKSVTLDWEPPAD 399
S EY+I A N IG+ + +VT T AP PPRNV ++ + WE P +
Sbjct: 381 SPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPARPPRNVQARMLSATTMIVQWEEPVE 440
Query: 400 DGGCKVG---NYIVEYYRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG--- 453
G G Y +E N W K T+ L+E Y R+ A + G
Sbjct: 441 PNGLIRGYRVYYTMEPEHPVGN-WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGP 499
Query: 454 MSAPSSESSPVRIPGRAIDM 473
+S P + +PG+ +++
Sbjct: 500 LSDPIQVKTQQGVPGQPMNL 519
Score = 38.3 bits (85), Expect = 0.15
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNVTL 433
P P N+ + + S+TL W PP + K Y + + + T+ +
Sbjct: 513 PGQPMNLRAEARSETSITLSWSPPRQESIIK---YELLFREGDHGREVGRTFDPTTSYVV 569
Query: 434 FDLIEGSEYKFRIKAESPYGMSA 456
DL +EY FR+ A SP G+ A
Sbjct: 570 EDLKPNTEYAFRLAARSPQGLGA 592
Score = 33.9 bits (74), Expect = 3.2
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PG P + +++ +IT+ W D P+ Y +E + S + +
Sbjct: 320 PKAPGTPMV----TENTATSITITWDSGNPD---PVSYYVIEY-KSKSQDGPYQIKEDIT 371
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ GL P +Y+ V+A+N +G SE V+T + ++A PP
Sbjct: 372 TTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSE--SVVTRTGEQAPARPP 418
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 66.5 bits (155), Expect = 5e-10
Identities = 72/296 (24%), Positives = 116/296 (39%), Gaps = 21/296 (7%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK--DDYEIFSSR-----RTAITTDESTS 240
I +L++ T EN +V G P P I W + D + R + +S
Sbjct: 304 IIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSS 363
Query: 241 VLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L + SD G C A +R GGH + L +E APK + +E N I
Sbjct: 364 SLHIKDVKLSDSGRYDCEAASRIGGHQKSMY-LDIEYAPK--FISNQTIYYSWEGNP-IN 419
Query: 300 LKTTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ + P +I WR D P ++ T + +L+I +D G Y A N
Sbjct: 420 ISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
Query: 358 IIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW 417
IG +++ + P P V + + + + P GG + +Y V+
Sbjct: 480 HIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVAS 539
Query: 418 NVWLKAITSR--KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS----ESSPVRIP 467
+W K + S +T V L +L + Y+ R+ A + G S ++ PVR P
Sbjct: 540 EIW-KIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREP 594
Score = 62.9 bits (146), Expect = 6e-09
Identities = 53/189 (28%), Positives = 80/189 (42%), Gaps = 13/189 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+ TA +++ F SG P P I+WF++ I + + + S + L I+ SD
Sbjct: 219 NATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYIL--KGSNTELTVRNIINSDG 276
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C ATN+ G +A L + P + Q ++ YE N + L G+P P I
Sbjct: 277 GPYVCRATNKAGEDEKQAFLQVFVQPHI---IQLKNETTYE-NGQVTLVCDAEGEPIPEI 332
Query: 313 EWRH--DGHPII-----TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
W+ DG D RIE+ S L I K SD G Y +A + IG +
Sbjct: 333 TWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKS 392
Query: 366 FLVTVTAPP 374
+ + P
Sbjct: 393 MYLDIEYAP 401
Score = 48.4 bits (110), Expect = 1e-04
Identities = 54/227 (23%), Positives = 98/227 (43%), Gaps = 17/227 (7%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYE-IFSSRRT 231
L VSS +A + + + ++E ++ K F T G P +I W+ E I S++R
Sbjct: 12 LLVSSGQALLQVTISLSKVE--LSVGESKF-FTCTAIGEPE-SIDWYNPQGEKIISTQRV 67
Query: 232 AITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLL 291
+ + S L + D G +C AT+ G +A + LE KL + R+
Sbjct: 68 VVQKEGVRSRLTIYNANIEDAGIYRCQATDAKGQ-TQEATVVLEIYQKLTF-REVVSPQE 125
Query: 292 YEINETIFLKTTIVGKPTPTIEWRHDGHPI--ITDDRIEISITPKFSVLKIHSAKRSDRG 349
++ E + + P P + W + + I+D+R + +L I+ +SD G
Sbjct: 126 FKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNIN---KSDEG 182
Query: 350 EYQIQAK-NIIGE-DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVT 391
Y+ + + GE D +V V PP P ++ + T + + +T
Sbjct: 183 IYRCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMT 229
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P + I+ + A P +H GG P+ YQV+ + S W + ++
Sbjct: 496 PSSPYGVKIIELSQTTAKVSFNKPDSH-GGVPIHHYQVDVKEVASEIW-KIVRSHGVQTM 553
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL 169
+VL LEP Y+ RVAA+N G +YS++
Sbjct: 554 VVLNNLEPNTTYEIRVAAVNGKGQGDYSKI 583
Score = 44.4 bits (100), Expect = 0.002
Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 11/181 (6%)
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + E S P+P ++W + E+ S R A+ + + +L I SDEG
Sbjct: 128 QGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQIL---NINKSDEGIY 184
Query: 256 KCTAT--NRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
+C RG + + P + P++ + E E + G P P I
Sbjct: 185 RCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATA-ERGEEMTFSCRASGSPEPAIS 243
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTA 372
W +G I ++ + + + L + + SD G Y +A N GED AFL
Sbjct: 244 WFRNGKLI--EENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQ 301
Query: 373 P 373
P
Sbjct: 302 P 302
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 66.5 bits (155), Expect = 5e-10
Identities = 60/220 (27%), Positives = 96/220 (43%), Gaps = 14/220 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP + ++ E V + V+ G P PTI W + D + + + +S +L
Sbjct: 224 EPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARR---HKSNGIL 280
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G +C A N G V + +L A P + ++ D + + E +F +
Sbjct: 281 EIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPN--WIQKIND-IHVAMEENVFWEC 337
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE- 361
G+P PT +W +G P++T DRI+I + L I SD G YQ A+N G
Sbjct: 338 KANGRPKPTYKWLKNGEPLLTRDRIQI----EQGTLNITIVNLSDAGMYQCLAENKHGVI 393
Query: 362 DTAAFLVTVTAPPDPPRNV--SVTR-QVDKSVTLDWEPPA 398
+ A L + PD R + VT +V V ++ +P A
Sbjct: 394 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKA 433
Score = 66.5 bits (155), Expect = 5e-10
Identities = 63/266 (23%), Positives = 103/266 (38%), Gaps = 19/266 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P P W K + + R I+ D + ++ + SD G C ATN G A +
Sbjct: 435 PKPVYTWKKGRDILKENERITISEDGNLRII---NVTKSDAGSYTCIATNHFGTASSTGN 491
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI--EWRHDGHPIITD---DR 326
L ++ ++ P D + E+I L + + I W +GH I D D
Sbjct: 492 LVVKDPTRVMVPPSSMD---VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDH 548
Query: 327 IE-ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
E + L I + + G+Y + + +AA + V PP PP V++
Sbjct: 549 FERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEI 608
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW---NVWLKAITSRKTNVTLFDLIEG 439
D + L W P D + Y+++ + GW + + I + T+ L
Sbjct: 609 TDTTAQLSWR-PGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPW 667
Query: 440 SEYKFRIKAESPYGMSAPSSESSPVR 465
EY+FR A + G+ PS S R
Sbjct: 668 VEYEFRTVAANVIGIGEPSRPSEKRR 693
Score = 39.5 bits (88), Expect = 0.063
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVL 136
PPG P+ + I + A L W P D +P+ Y ++ S W + T P ++
Sbjct: 596 PPGPPEAVTIDEITDTTA-QLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELID 653
Query: 137 RPELVLT--GLEPPHKYQFRVAALNDVGHSNYSELSD 171
T GL P +Y+FR A N +G S S+
Sbjct: 654 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSE 690
Score = 34.3 bits (75), Expect = 2.4
Identities = 48/203 (23%), Positives = 82/203 (40%), Gaps = 24/203 (11%)
Query: 169 LSDVLTVSSDRASQEPPVFIKRLEDVTA---LENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
L + +D ++ P+FI+ V E KV+ + G P P I W + ++
Sbjct: 10 LQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDV 69
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
+ + E S+L+ + D G +CTATN G V++ EA KL++
Sbjct: 70 DTGMDFRYSVVEG-SLLINNPNKTQDAGTYQCTATNSFGTIVSR-----EA--KLQF--A 119
Query: 286 YEDGLLYEINETIFLK-----TTIVGKPTPTIE----WRHDGHPIITDDRIEISITPKFS 336
Y D T+ ++ + G P + E W + +P D+R +S +
Sbjct: 120 YLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVS--QETG 177
Query: 337 VLKIHSAKRSDRGEYQIQAKNII 359
L I ++SD G Y N +
Sbjct: 178 NLYIAKVEKSDVGNYTCVVTNTV 200
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 66.5 bits (155), Expect = 5e-10
Identities = 60/220 (27%), Positives = 96/220 (43%), Gaps = 14/220 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP + ++ E V + V+ G P PTI W + D + + + +S +L
Sbjct: 224 EPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARR---HKSNGIL 280
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G +C A N G V + +L A P + ++ D + + E +F +
Sbjct: 281 EIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPN--WIQKIND-IHVAMEENVFWEC 337
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE- 361
G+P PT +W +G P++T DRI+I + L I SD G YQ A+N G
Sbjct: 338 KANGRPKPTYKWLKNGEPLLTRDRIQI----EQGTLNITIVNLSDAGMYQCLAENKHGVI 393
Query: 362 DTAAFLVTVTAPPDPPRNV--SVTR-QVDKSVTLDWEPPA 398
+ A L + PD R + VT +V V ++ +P A
Sbjct: 394 FSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKA 433
Score = 66.5 bits (155), Expect = 5e-10
Identities = 63/266 (23%), Positives = 103/266 (38%), Gaps = 19/266 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P P W K + + R I+ D + ++ + SD G C ATN G A +
Sbjct: 435 PKPVYTWKKGRDILKENERITISEDGNLRII---NVTKSDAGSYTCIATNHFGTASSTGN 491
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI--EWRHDGHPIITD---DR 326
L ++ ++ P D + E+I L + + I W +GH I D D
Sbjct: 492 LVVKDPTRVMVPPSSMD---VTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDH 548
Query: 327 IE-ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
E + L I + + G+Y + + +AA + V PP PP V++
Sbjct: 549 FERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEI 608
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEY---YRTGW---NVWLKAITSRKTNVTLFDLIEG 439
D + L W P D + Y+++ + GW + + I + T+ L
Sbjct: 609 TDTTAQLSWR-PGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPW 667
Query: 440 SEYKFRIKAESPYGMSAPSSESSPVR 465
EY+FR A + G+ PS S R
Sbjct: 668 VEYEFRTVAANVIGIGEPSRPSEKRR 693
Score = 39.5 bits (88), Expect = 0.063
Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 6/97 (6%)
Query: 79 PPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVL 136
PPG P+ + I + A L W P D +P+ Y ++ S W + T P ++
Sbjct: 596 PPGPPEAVTIDEITDTTA-QLSWRPGP-DNHSPITMYVIQARTPFSVGWQAVSTVPELID 653
Query: 137 RPELVLT--GLEPPHKYQFRVAALNDVGHSNYSELSD 171
T GL P +Y+FR A N +G S S+
Sbjct: 654 GKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSE 690
Score = 34.3 bits (75), Expect = 2.4
Identities = 48/203 (23%), Positives = 82/203 (40%), Gaps = 24/203 (11%)
Query: 169 LSDVLTVSSDRASQEPPVFIKRLEDVTA---LENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
L + +D ++ P+FI+ V E KV+ + G P P I W + ++
Sbjct: 10 LQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDV 69
Query: 226 FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ 285
+ + E S+L+ + D G +CTATN G V++ EA KL++
Sbjct: 70 DTGMDFRYSVVEG-SLLINNPNKTQDAGTYQCTATNSFGTIVSR-----EA--KLQF--A 119
Query: 286 YEDGLLYEINETIFLK-----TTIVGKPTPTIE----WRHDGHPIITDDRIEISITPKFS 336
Y D T+ ++ + G P + E W + +P D+R +S +
Sbjct: 120 YLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVS--QETG 177
Query: 337 VLKIHSAKRSDRGEYQIQAKNII 359
L I ++SD G Y N +
Sbjct: 178 NLYIAKVEKSDVGNYTCVVTNTV 200
>DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine
phosphatase receptor type F protein.
Length = 262
Score = 66.1 bits (154), Expect = 6e-10
Identities = 58/186 (31%), Positives = 84/186 (45%), Gaps = 14/186 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST-SVLL 243
PVFIK ED T L F +G P P I W K ++ S R I D+ SVL
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 244 FHQI-LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKL--RYPRQYEDGLLYEINETIFL 300
+ + DE +CTATN G T A+L + +L +P + G ++ E
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGGINTSAKLSVLEEEQLPPGFP-SIDMGPQLKVVEKART 151
Query: 301 KTTIV---GKPTPTIEWRHDGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
T + G P P I W D P+ ++ RI+ + L+I S++ SD+G+Y+
Sbjct: 152 ATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIK---QLRSGALQIESSEESDQGKYECV 208
Query: 355 AKNIIG 360
A N G
Sbjct: 209 ATNSAG 214
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 65.3 bits (152), Expect = 1e-09
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 21/267 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W K + +S R +T D L+ I SDEG+ C A N G A +
Sbjct: 446 PKAVVLWSKGTEILVNSSRVTVTPD---GTLIIRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEWRHDGHPIITDDR--- 326
L + A K+ D + + + L+ PT T W D PI D
Sbjct: 503 LSVRDATKITLAPSSAD---INLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 327 -IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
++ L I +A+ G+Y A+ ++ + V V PP PP V V
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDI 619
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV-------TLFDLIE 438
D ++ L W D+ + Y ++ W K + + N+ + L
Sbjct: 620 GDTTIQLSWSRGFDNHS-PIAKYTLQARTPPAGKW-KQVRTNPANIEGNAETAQVLGLTP 677
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVR 465
+Y+FR+ A + G PS SS +R
Sbjct: 678 WMDYEFRVIASNILGTGEPSGPSSKIR 704
Score = 59.7 bits (138), Expect = 6e-08
Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 16/214 (7%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ + + + D P + + + AL +V G P P I W K D
Sbjct: 219 SVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDG 278
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ TA T + SV DEG +C A N G + R+ ++A P+ +
Sbjct: 279 SLSPQWTTAEPTLQIPSVSF------EDEGTYECEAENSKGRDTVQGRIIVQAQPE--WL 330
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHS 342
+ D +I + GKP PT+ W +G P+ + +R+E+ +FS L +
Sbjct: 331 KVISDTEA-DIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSL-- 387
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-PPD 375
D G YQ A+N G A+ + V A PD
Sbjct: 388 ---EDSGMYQCVAENKHGTIYASAELAVQALAPD 418
Score = 41.5 bits (93), Expect = 0.016
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 20/194 (10%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK-- 269
P + W +++ F ++T L + SD G C AT+ +
Sbjct: 162 PGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVF 221
Query: 270 ---ARLCLEA------APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
A+L L A AP ++ E L + + + L+ G P P I+WR
Sbjct: 222 SKFAQLNLAAEDTRLFAPSIKARFPAETYAL--VGQQVTLECFAFGNPVPRIKWRK---- 275
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
D + T L+I S D G Y+ +A+N G DT + V A P+ + +
Sbjct: 276 --VDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 381 SVTRQVDKSVTLDW 394
S T + D L W
Sbjct: 334 SDT-EADIGSNLRW 346
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 65.3 bits (152), Expect = 1e-09
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 21/267 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W K + +S R +T D L+ I SDEG+ C A N G A +
Sbjct: 446 PKAVVLWSKGTEILVNSSRVTVTPD---GTLIIRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEWRHDGHPIITDDR--- 326
L + A K+ D + + + L+ PT T W D PI D
Sbjct: 503 LSVRDATKITLAPSSAD---INLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 327 -IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
++ L I +A+ G+Y A+ ++ + V V PP PP V V
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDI 619
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV-------TLFDLIE 438
D ++ L W D+ + Y ++ W K + + N+ + L
Sbjct: 620 GDTTIQLSWSRGFDNHS-PIAKYTLQARTPPAGKW-KQVRTNPANIEGNAETAQVLGLTP 677
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVR 465
+Y+FR+ A + G PS SS +R
Sbjct: 678 WMDYEFRVIASNILGTGEPSGPSSKIR 704
Score = 59.7 bits (138), Expect = 6e-08
Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 16/214 (7%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ + + + D P + + + AL +V G P P I W K D
Sbjct: 219 SVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDG 278
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ TA T + SV DEG +C A N G + R+ ++A P+ +
Sbjct: 279 SLSPQWTTAEPTLQIPSVSF------EDEGTYECEAENSKGRDTVQGRIIVQAQPE--WL 330
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHS 342
+ D +I + GKP PT+ W +G P+ + +R+E+ +FS L +
Sbjct: 331 KVISDTEA-DIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSL-- 387
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-PPD 375
D G YQ A+N G A+ + V A PD
Sbjct: 388 ---EDSGMYQCVAENKHGTIYASAELAVQALAPD 418
Score = 41.5 bits (93), Expect = 0.016
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 20/194 (10%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK-- 269
P + W +++ F ++T L + SD G C AT+ +
Sbjct: 162 PGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVF 221
Query: 270 ---ARLCLEA------APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
A+L L A AP ++ E L + + + L+ G P P I+WR
Sbjct: 222 SKFAQLNLAAEDTRLFAPSIKARFPAETYAL--VGQQVTLECFAFGNPVPRIKWRK---- 275
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
D + T L+I S D G Y+ +A+N G DT + V A P+ + +
Sbjct: 276 --VDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 381 SVTRQVDKSVTLDW 394
S T + D L W
Sbjct: 334 SDT-EADIGSNLRW 346
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 65.3 bits (152), Expect = 1e-09
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 21/267 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W K + +S R +T D L+ I SDEG+ C A N G A +
Sbjct: 446 PKAVVLWSKGTEILVNSSRVTVTPD---GTLIIRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEWRHDGHPIITDDR--- 326
L + A K+ D + + + L+ PT T W D PI D
Sbjct: 503 LSVRDATKITLAPSSAD---INLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 327 -IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
++ L I +A+ G+Y A+ ++ + V V PP PP V V
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDI 619
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV-------TLFDLIE 438
D ++ L W D+ + Y ++ W K + + N+ + L
Sbjct: 620 GDTTIQLSWSRGFDNHS-PIAKYTLQARTPPAGKW-KQVRTNPANIEGNAETAQVLGLTP 677
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVR 465
+Y+FR+ A + G PS SS +R
Sbjct: 678 WMDYEFRVIASNILGTGEPSGPSSKIR 704
Score = 59.7 bits (138), Expect = 6e-08
Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 16/214 (7%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ + + + D P + + + AL +V G P P I W K D
Sbjct: 219 SVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDG 278
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ TA T + SV DEG +C A N G + R+ ++A P+ +
Sbjct: 279 SLSPQWTTAEPTLQIPSVSF------EDEGTYECEAENSKGRDTVQGRIIVQAQPE--WL 330
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHS 342
+ D +I + GKP PT+ W +G P+ + +R+E+ +FS L +
Sbjct: 331 KVISDTEA-DIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSL-- 387
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-PPD 375
D G YQ A+N G A+ + V A PD
Sbjct: 388 ---EDSGMYQCVAENKHGTIYASAELAVQALAPD 418
Score = 41.5 bits (93), Expect = 0.016
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 20/194 (10%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK-- 269
P + W +++ F ++T L + SD G C AT+ +
Sbjct: 162 PGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVF 221
Query: 270 ---ARLCLEA------APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
A+L L A AP ++ E L + + + L+ G P P I+WR
Sbjct: 222 SKFAQLNLAAEDTRLFAPSIKARFPAETYAL--VGQQVTLECFAFGNPVPRIKWRK---- 275
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
D + T L+I S D G Y+ +A+N G DT + V A P+ + +
Sbjct: 276 --VDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 381 SVTRQVDKSVTLDW 394
S T + D L W
Sbjct: 334 SDT-EADIGSNLRW 346
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 47.2 bits (107), Expect = 3e-04
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 19/141 (13%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHA---VTKARLCLEAAPK---------LRYPRQYEDGLLYEINETIFL 300
G+ +C A N G A V K + E+ P+ LR P + + L
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHN----VTFGSFVTL 241
Query: 301 KTTIVGKPTPTIEWRHDGHPI 321
T G P PTI W +G+ +
Sbjct: 242 HCTATGIPVPTITWIENGNAV 262
Score = 41.9 bits (94), Expect = 0.012
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 6/123 (4%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL---EDVTALENDKVEFHVTF 208
Q+R A N +G + YS++ + Q+ VF + L E V H T
Sbjct: 187 QYRCVAKNSLGTA-YSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTA 245
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP PTI W ++ + S D L Q+ + G C ATN+ G +
Sbjct: 246 TGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATNKHGEKFS 303
Query: 269 KAR 271
A+
Sbjct: 304 TAK 306
>BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein.
Length = 179
Score = 65.3 bits (152), Expect = 1e-09
Identities = 46/170 (27%), Positives = 70/170 (41%), Gaps = 6/170 (3%)
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKC 257
E V F SG PSP I WFK++ I S +I+ + L SD G+
Sbjct: 4 EGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 63
Query: 258 TATN-RGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRH 316
A N RG + T + + L PK+ + + + + + G+PTP + W
Sbjct: 64 KAKNFRGQCSATASLMVLRIPPKI---EALPSDISIDEGKVLTVACAFTGEPTPEVTWSC 120
Query: 317 DGHPIITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
G I + + R I T + L I ++ D G Y + N G D+A
Sbjct: 121 GGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSA 170
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ + I G+P+P IEW + PI + IS + L+I +A SD G+Y I+A
Sbjct: 6 QNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKA 65
Query: 356 KNIIGEDTA-AFLVTVTAPP 374
KN G+ +A A L+ + PP
Sbjct: 66 KNFRGQCSATASLMVLRIPP 85
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 65.3 bits (152), Expect = 1e-09
Identities = 64/267 (23%), Positives = 101/267 (37%), Gaps = 21/267 (7%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P + W K + +S R +T D L+ I SDEG+ C A N G A +
Sbjct: 446 PKAVVLWSKGTEILVNSSRVTVTPD---GTLIIRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP--TIEWRHDGHPIITDDR--- 326
L + A K+ D + + + L+ PT T W D PI D
Sbjct: 503 LSVRDATKITLAPSSAD---INLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 327 -IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQ 385
++ L I +A+ G+Y A+ ++ + V V PP PP V V
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRDI 619
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTNV-------TLFDLIE 438
D ++ L W D+ + Y ++ W K + + N+ + L
Sbjct: 620 GDTTIQLSWSRGFDNHS-PIAKYTLQARTPPAGKW-KQVRTNPANIEGNAETAQVLGLTP 677
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVR 465
+Y+FR+ A + G PS SS +R
Sbjct: 678 WMDYEFRVIASNILGTGEPSGPSSKIR 704
Score = 59.7 bits (138), Expect = 6e-08
Identities = 56/214 (26%), Positives = 89/214 (41%), Gaps = 16/214 (7%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ + + + D P + + + AL +V G P P I W K D
Sbjct: 219 SVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDG 278
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ TA T + SV DEG +C A N G + R+ ++A P+ +
Sbjct: 279 SLSPQWTTAEPTLQIPSVSF------EDEGTYECEAENSKGRDTVQGRIIVQAQPE--WL 330
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHS 342
+ D +I + GKP PT+ W +G P+ + +R+E+ +FS L +
Sbjct: 331 KVISDTEA-DIGSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGDLRFSKLSL-- 387
Query: 343 AKRSDRGEYQIQAKNIIGEDTAAFLVTVTA-PPD 375
D G YQ A+N G A+ + V A PD
Sbjct: 388 ---EDSGMYQCVAENKHGTIYASAELAVQALAPD 418
Score = 41.5 bits (93), Expect = 0.016
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 20/194 (10%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK-- 269
P + W +++ F ++T L + SD G C AT+ +
Sbjct: 162 PGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVF 221
Query: 270 ---ARLCLEA------APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
A+L L A AP ++ E L + + + L+ G P P I+WR
Sbjct: 222 SKFAQLNLAAEDTRLFAPSIKARFPAETYAL--VGQQVTLECFAFGNPVPRIKWRK---- 275
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNV 380
D + T L+I S D G Y+ +A+N G DT + V A P+ + +
Sbjct: 276 --VDGSLSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVI 333
Query: 381 SVTRQVDKSVTLDW 394
S T + D L W
Sbjct: 334 SDT-EADIGSNLRW 346
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 6/176 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
PV LE V AL + F P P I+W ++ + T + E+ +L
Sbjct: 28 PVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKI-LIKLFDTRYSIRENGQLLTI 86
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ SD+G CTA N G AV L+ K + R + + E + + L T
Sbjct: 87 LSVEDSDDGIYCCTANNGVGGAVESCG-ALQVKMKPKITRPPINVKIIEGLKAV-LPCTT 144
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
+G P P++ W P+ + RI + + L+IH+ ++ D G+Y+ AKN +G
Sbjct: 145 MGNPKPSVSWIKGDSPLRENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Score = 54.0 bits (124), Expect = 3e-06
Identities = 40/131 (30%), Positives = 59/131 (45%), Gaps = 9/131 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+V +E K T G P P+++W K D + + R A+ ES S L H + D
Sbjct: 129 NVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVL--ESGS-LRIHNVQKEDA 185
Query: 253 GEIKCTATNRGGHAVTK-ARLCLEA-APKLRYPRQYEDGLLYEINETIFLKTTIVGKPTP 310
G+ +C A N G A +K +L +E A LR P + + L T G P P
Sbjct: 186 GQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHN----VTFGSFVTLHCTATGIPVP 241
Query: 311 TIEWRHDGHPI 321
TI W +G+ +
Sbjct: 242 TITWIENGNAV 252
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Query: 202 VEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN 261
V H T +GIP PTI W ++ + S D L Q+ + G C ATN
Sbjct: 229 VTLHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRL--QLFITKPGLYTCIATN 286
Query: 262 RGGHAVTKAR 271
+ G + A+
Sbjct: 287 KHGEKFSTAK 296
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 65.3 bits (152), Expect = 1e-09
Identities = 59/220 (26%), Positives = 98/220 (44%), Gaps = 14/220 (6%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EP + ++ E + A + V+ G P P I W + D FSS+ I + + VL
Sbjct: 118 EPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSK---IKLRKFSGVL 174
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
D G +C A N G V + RL A P + + +D + + ++++ +
Sbjct: 175 EIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKP--HWVQLIKD-VEIAVEDSLYWEC 231
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG-E 361
GKP P+ W +G ++ ++R +I + L I + +D G +Q A+N G
Sbjct: 232 RASGKPKPSYRWLKNGAALVLEERTQI----ENGALTISNLSVTDSGMFQCIAENKHGLV 287
Query: 362 DTAAFLVTVTAPPD---PPRNVSVTRQVDKSVTLDWEPPA 398
++A L V + PD P V QV V+LD +P A
Sbjct: 288 YSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRA 327
Score = 51.2 bits (117), Expect = 2e-05
Identities = 56/265 (21%), Positives = 97/265 (36%), Gaps = 18/265 (6%)
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKAR 271
P +W K D + R ++ D + + +D G C A N+ G A
Sbjct: 329 PRALSSWKKGDVSVQEHERISLLNDGGLKIA---NVTKADAGTYTCMAENQFGKANGTTH 385
Query: 272 LCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISI 331
L + ++ D + E++ L + P I + + + D + + S
Sbjct: 386 LVVTEPTRITLAPSNMD---VSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSH 442
Query: 332 TPKFSV-----LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQV 386
K L I + + G+Y + + ++A + V P PP NV V
Sbjct: 443 FEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEIT 502
Query: 387 DKSVTLDWEPPADDGGCKVGNYIVEY---YRTGWNVWL---KAITSRKTNVTLFDLIEGS 440
D + L W+ D V +Y ++ + GW + I + T+ +L
Sbjct: 503 DTTAQLSWK-EGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWV 561
Query: 441 EYKFRIKAESPYGMSAPSSESSPVR 465
EY+FR+ A + G PS S VR
Sbjct: 562 EYEFRVVASNKIGGGEPSLPSEKVR 586
Score = 50.8 bits (116), Expect = 3e-05
Identities = 47/211 (22%), Positives = 82/211 (38%), Gaps = 12/211 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P +++ ++DV D + + SG P P+ W K+ + RT I L
Sbjct: 210 PHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQI----ENGALTI 265
Query: 245 HQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTI 304
+ +D G +C A N+ G + A L + A+ + + ++ + L
Sbjct: 266 SNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKP 325
Query: 305 VGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA 364
P W+ + +RI + LKI + ++D G Y A+N G+
Sbjct: 326 RASPRALSSWKKGDVSVQEHERISLL---NDGGLKIANVTKADAGTYTCMAENQFGKANG 382
Query: 365 AFLVTVTAPPD---PPRNVSVTRQVDKSVTL 392
+ VT P P N+ V+ V +SV L
Sbjct: 383 TTHLVVTEPTRITLAPSNMDVS--VGESVIL 411
Score = 50.0 bits (114), Expect = 4e-05
Identities = 68/261 (26%), Positives = 114/261 (43%), Gaps = 33/261 (12%)
Query: 217 AWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEA 276
AW ++Y F + + T L ++ PSD G C T+ VT AR+
Sbjct: 48 AWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTS----MVTNARVLGSP 103
Query: 277 APKL--------RY-PR---QYEDGLLYEINETIFLKTTIVGKPTPTIEWRH-DGHPIIT 323
P + Y P+ Q+ + L T+ L+ +G P P I WR DG P +
Sbjct: 104 TPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSS 163
Query: 324 DDRIEISITPKFS-VLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
++ KFS VL+I + ++ D G Y+ A+N G++ A +T A P V +
Sbjct: 164 KIKLR-----KFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYA---KPHWVQL 215
Query: 383 TRQVDKSV--TLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITSRKTN-VTLFDLIEG 439
+ V+ +V +L WE A G +Y + + G + L+ T + +T+ +L
Sbjct: 216 IKDVEIAVEDSLYWECRA--SGKPKPSY--RWLKNGAALVLEERTQIENGALTISNLSVT 271
Query: 440 SEYKFRIKAESPYGMSAPSSE 460
F+ AE+ +G+ S+E
Sbjct: 272 DSGMFQCIAENKHGLVYSSAE 292
Score = 37.9 bits (84), Expect = 0.19
Identities = 36/115 (31%), Positives = 52/115 (45%), Gaps = 8/115 (6%)
Query: 371 TAPPDPPRNVSVTRQVDKSVTLDWEP-PADDGGCKVGNYIVEYYRTGWNVWLKAITSRKT 429
T P PP NV V D V L+WE A + +V Y V +YRT ++ + + KT
Sbjct: 793 TPPSQPPGNV-VWNATDTKVLLNWEQVKAMENESEVTGYKV-FYRTSSQNNVQVLNTNKT 850
Query: 430 NVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVEARIIN 484
+ L I+ +Y +KA + G + S +RIP R MD + I N
Sbjct: 851 SAELVLPIK-EDYIIEVKATTDGG---DGTSSEQIRIP-RITSMDARGSTSAISN 900
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 798 PHFLQTPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 858 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 917
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 918 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 977
Query: 360 G 360
G
Sbjct: 978 G 978
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ D G CTA+N+ G + A+L + L +G L+ N
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 274
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 275 TTNL-AAIEPQPSP 287
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F KRL+ E V F GIP P + WFKD +I E
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 245 H--QILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
H D+G A N G L +++ P
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 765
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 869 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 923
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 924 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 984 ARLDIYA 990
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 1193 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252
Query: 360 G 360
G
Sbjct: 1253 G 1253
Score = 49.6 bits (113), Expect = 6e-05
Identities = 35/134 (26%), Positives = 59/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEP 494
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ G CTA+N+ G + A+L + L +G L+ N
Sbjct: 495 EEICTLVIAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 549
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 550 TTNL-AAIEPQPSP 562
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F KRL+ E V F GIP P + WFKD +I E
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 245 H--QILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
H D+G A N G L +++ P
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 1040
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/93 (25%), Positives = 39/93 (41%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+PP F ++L E +V+ GIP P + W+ + E+ +S I + L
Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 326
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D G C A+N G T A + +E
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 1144 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 1259 ARLDIYA 1265
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 26/66 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L +VG P P + W +G + I I L I A D G Y A NI
Sbjct: 288 LDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIY 347
Query: 360 GEDTAA 365
G D+ +
Sbjct: 348 GTDSTS 353
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 1193 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252
Query: 360 G 360
G
Sbjct: 1253 G 1253
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ D G CTA+N+ G + A+L + L +G L+ N
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 549
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 550 TTNL-AAIEPQPSP 562
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F KRL+ E V F GIP P + WFKD +I E
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 245 H--QILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
H D+G A N G L +++ P
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 1040
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/93 (25%), Positives = 39/93 (41%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+PP F ++L E +V+ GIP P + W+ + E+ +S I + L
Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 326
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D G C A+N G T A + +E
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 1144 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 1259 ARLDIYA 1265
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 26/66 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L +VG P P + W +G + I I L I A D G Y A NI
Sbjct: 288 LDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIY 347
Query: 360 GEDTAA 365
G D+ +
Sbjct: 348 GTDSTS 353
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 798 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 857
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 858 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 917
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 918 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 977
Query: 360 G 360
G
Sbjct: 978 G 978
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 160 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 219
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ D G CTA+N+ G + A+L + L +G L+ N
Sbjct: 220 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 274
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 275 TTNL-AAIEPQPSP 287
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F KRL+ E V F GIP P + WFKD +I E
Sbjct: 670 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 729
Query: 245 H--QILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
H D+G A N G L +++ P
Sbjct: 730 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 765
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 869 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 923
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 924 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 983
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 984 ARLDIYA 990
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 64.5 bits (150), Expect = 2e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1192
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 1193 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252
Query: 360 G 360
G
Sbjct: 1253 G 1253
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ D G CTA+N+ G + A+L + L +G L+ N
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 549
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 550 TTNL-AAIEPQPSP 562
Score = 42.7 bits (96), Expect = 0.007
Identities = 26/96 (27%), Positives = 34/96 (35%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P+F KRL+ E V F GIP P + WFKD +I E
Sbjct: 945 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSL 1004
Query: 245 H--QILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
H D+G A N G L +++ P
Sbjct: 1005 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 1040
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/93 (25%), Positives = 39/93 (41%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+PP F ++L E +V+ GIP P + W+ + E+ +S I + L
Sbjct: 267 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 326
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D G C A+N G T A + +E
Sbjct: 327 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 1144 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 1198
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 1199 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1258
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 1259 ARLDIYA 1265
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 26/66 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L +VG P P + W +G + I I L I A D G Y A NI
Sbjct: 288 LDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIY 347
Query: 360 GEDTAA 365
G D+ +
Sbjct: 348 GTDSTS 353
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 64.5 bits (150), Expect = 2e-09
Identities = 75/313 (23%), Positives = 120/313 (38%), Gaps = 26/313 (8%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 440 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 499
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A + L ++ A + +Q E ++ + F
Sbjct: 500 IPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWI--VKQPEYAVVQRGSMVSFEC 555
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 556 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 611
Query: 361 EDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
+A+ +++V AP P+PP ++ +T Q+DKSV L W P DD + +I+
Sbjct: 612 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFII 670
Query: 411 EY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
EY ++ G ++ +T L +L Y FR+ A + G S PS S
Sbjct: 671 EYEDAMHKPGLWHHQTEVSGTQTTAQL-NLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 729
Query: 467 PGRAIDMDFLAVE 479
D + AVE
Sbjct: 730 KASEPDKNPTAVE 742
Score = 48.8 bits (111), Expect = 1e-04
Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 14/211 (6%)
Query: 172 VLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS 228
V +S+ + + PP F+ + L + + G+P+P I W K+D +
Sbjct: 243 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED-GMLPK 301
Query: 229 RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED 288
RT E T ++ + +D G +C A N G + ++AAP Y
Sbjct: 302 NRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKAAP---YWITAPQ 356
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEISITPKFSVLKIHSAKRSD 347
L+ E L G P P I W +G PI I D I +++ + +RS
Sbjct: 357 NLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-TIIFSNVQERSS 415
Query: 348 RGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
YQ A N G A V V A +PPR
Sbjct: 416 -AVYQCNASNEYGYLLANAFVNVLA--EPPR 443
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 940 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 997
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 998 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1032
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 64.1 bits (149), Expect = 3e-09
Identities = 75/305 (24%), Positives = 117/305 (38%), Gaps = 30/305 (9%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ S+ L
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG--SNLDGGNYHVYENGSLE 487
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + R LE R R ED + T+ L+
Sbjct: 488 IKMIRKEDQGIYTCVATNILGKAENQVR--LEVKDPTRIYRMPEDQVARR-GTTVQLECR 544
Query: 304 IVGKPT--PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 545 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 362 DTAAFLVTVTAP---------------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D A +TV A PD PR++ +T ++SV L W P D +
Sbjct: 601 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPIT 659
Query: 407 NYIVEYYRTGW--NVWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
+Y+V++ + VW + N + L Y+FR+ A + G S PS S
Sbjct: 660 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 719
Query: 464 VRIPG 468
R G
Sbjct: 720 YRTSG 724
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 271 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 327
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 328 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 385 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 437
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 17/184 (9%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+PSP I W E + + ++ + + + +L + + C A H + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKR-VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 225
Query: 270 ----------ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
R E P YP+ + + L+ G PTP I W G
Sbjct: 226 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 285
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DP 376
+ D+ + K L+I + D GEY A N +G V V A P D
Sbjct: 286 D-LPSDKAKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 342
Query: 377 PRNV 380
P+N+
Sbjct: 343 PKNL 346
Score = 37.1 bits (82), Expect = 0.34
Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 350 EYQIQAKNIIG---EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
E ++QA+N G E + + P PR V + +++ L+W+ P G +G
Sbjct: 798 EIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG 857
Query: 407 NYIVEYYR-TGWNVWLKAITSRKTNVTLFDLIEG---SEYKFRIKAESPYGMSAPSSESS 462
Y ++Y G V + + + N T F + S Y+F + A + G +E S
Sbjct: 858 -YTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEES 916
Query: 463 P 463
P
Sbjct: 917 P 917
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 64.1 bits (149), Expect = 3e-09
Identities = 48/181 (26%), Positives = 74/181 (40%), Gaps = 5/181 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIF-SSRRTAITTDESTSVLL 243
P F++ D+ A E SG+P P + W + + + + + LL
Sbjct: 1144 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLL 1203
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE--TIFLK 301
+ D G KC ATN+ G L + A + P E + E + L+
Sbjct: 1204 IDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLE 1263
Query: 302 TTIVGKPTPTIEWRHDGHPI-ITDDRIEI-SITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
++G P P W+ D I T +RI + T ++ L I AK+SD G Y + AKN
Sbjct: 1264 CRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1323
Query: 360 G 360
G
Sbjct: 1324 G 1324
Score = 53.2 bits (122), Expect = 5e-06
Identities = 36/134 (26%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD--------DYEIFSSRRTAITTD 236
PVF K L++++A E V F G PSP + W+++ D+ I + ++
Sbjct: 506 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 565
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE 296
E L+ ++ D G CTA+N+ G + A+L + L +G L+ N
Sbjct: 566 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLS-----NNGSLHSANS 620
Query: 297 TIFLKTTIVGKPTP 310
T L I +P+P
Sbjct: 621 TTNL-AAIEPQPSP 633
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 2/96 (2%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS-SRRTAITTD-ESTSVL 242
P+F KRL+ E V F GIP P + WFKD +I + R + + + T L
Sbjct: 1016 PIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSL 1075
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAP 278
D+G A N G L +++ P
Sbjct: 1076 HIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP 1111
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/93 (25%), Positives = 39/93 (41%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
+PP F ++L E +V+ GIP P + W+ + E+ +S I + L
Sbjct: 338 QPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSL 397
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D G C A+N G T A + +E
Sbjct: 398 TIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 430
Score = 40.7 bits (91), Expect = 0.027
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 8/127 (6%)
Query: 153 FRVAALNDVGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ A N G +++S ELS V + ++ PV +++L++ E V G+
Sbjct: 1215 YKCIATNKTGQNSFSLELSVVA-----KEVKKAPVILEKLQNCGVPEGHPVRLECRVIGM 1269
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDEST--SVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
P P W KD+ I +R ++T + LL SD G +A N G
Sbjct: 1270 PPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCT 1329
Query: 270 ARLCLEA 276
ARL + A
Sbjct: 1330 ARLDIYA 1336
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 26/66 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L +VG P P + W +G + I I L I A D G Y A NI
Sbjct: 359 LDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIY 418
Query: 360 GEDTAA 365
G D+ +
Sbjct: 419 GTDSTS 424
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 64.1 bits (149), Expect = 3e-09
Identities = 75/305 (24%), Positives = 117/305 (38%), Gaps = 30/305 (9%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ S+ L
Sbjct: 399 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG--SNLDGGNYHVYENGSLE 456
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + R LE R R ED + T+ L+
Sbjct: 457 IKMIRKEDQGIYTCVATNILGKAENQVR--LEVKDPTRIYRMPEDQVARR-GTTVQLECR 513
Query: 304 IVGKPT--PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 514 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 569
Query: 362 DTAAFLVTVTAP---------------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D A +TV A PD PR++ +T ++SV L W P D +
Sbjct: 570 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPIT 628
Query: 407 NYIVEYYRTGW--NVWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
+Y+V++ + VW + N + L Y+FR+ A + G S PS S
Sbjct: 629 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 688
Query: 464 VRIPG 468
R G
Sbjct: 689 YRTSG 693
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 240 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 296
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 297 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 353
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 354 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 406
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 17/184 (9%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+PSP I W E + + ++ + + + +L + + C A H + +
Sbjct: 136 GLPSPVIFWMSSSMEPITQDKR-VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 194
Query: 270 ----------ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
R E P YP+ + + L+ G PTP I W G
Sbjct: 195 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 254
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DP 376
+ D+ + K L+I + D GEY A N +G V V A P D
Sbjct: 255 D-LPSDKAKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 311
Query: 377 PRNV 380
P+N+
Sbjct: 312 PKNL 315
Score = 37.1 bits (82), Expect = 0.34
Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 350 EYQIQAKNIIG---EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
E ++QA+N G E + + P PR V + +++ L+W+ P G +G
Sbjct: 767 EIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG 826
Query: 407 NYIVEYYR-TGWNVWLKAITSRKTNVTLFDLIEG---SEYKFRIKAESPYGMSAPSSESS 462
Y ++Y G V + + + N T F + S Y+F + A + G +E S
Sbjct: 827 -YTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEES 885
Query: 463 P 463
P
Sbjct: 886 P 886
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 64.1 bits (149), Expect = 3e-09
Identities = 75/305 (24%), Positives = 117/305 (38%), Gaps = 30/305 (9%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ S+ L
Sbjct: 417 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG--SNLDGGNYHVYENGSLE 474
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + R LE R R ED + T+ L+
Sbjct: 475 IKMIRKEDQGIYTCVATNILGKAENQVR--LEVKDPTRIYRMPEDQVARR-GTTVQLECR 531
Query: 304 IVGKPT--PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 532 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 587
Query: 362 DTAAFLVTVTAP---------------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D A +TV A PD PR++ +T ++SV L W P D +
Sbjct: 588 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPIT 646
Query: 407 NYIVEYYRTGW--NVWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
+Y+V++ + VW + N + L Y+FR+ A + G S PS S
Sbjct: 647 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 706
Query: 464 VRIPG 468
R G
Sbjct: 707 YRTSG 711
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 258 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 314
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 315 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 371
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 372 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 424
Score = 39.1 bits (87), Expect = 0.084
Identities = 32/114 (28%), Positives = 44/114 (38%), Gaps = 6/114 (5%)
Query: 270 ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEI 329
AR E P YP+ + + L+ G PTP I W G + D+ +
Sbjct: 223 ARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGD-LPSDKAKF 281
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DPPRNV 380
K L+I + D GEY A N +G V V A P D P+N+
Sbjct: 282 ENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNL 333
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 919 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 977
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 978 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1011
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 64.1 bits (149), Expect = 3e-09
Identities = 75/305 (24%), Positives = 117/305 (38%), Gaps = 30/305 (9%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ S+ L
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG--SNLDGGNYHVYENGSLE 487
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + R LE R R ED + T+ L+
Sbjct: 488 IKMIRKEDQGIYTCVATNILGKAENQVR--LEVKDPTRIYRMPEDQVARR-GTTVQLECR 544
Query: 304 IVGKPT--PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 545 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 362 DTAAFLVTVTAP---------------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D A +TV A PD PR++ +T ++SV L W P D +
Sbjct: 601 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPIT 659
Query: 407 NYIVEYYRTGW--NVWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
+Y+V++ + VW + N + L Y+FR+ A + G S PS S
Sbjct: 660 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 719
Query: 464 VRIPG 468
R G
Sbjct: 720 YRTSG 724
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 271 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 327
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 328 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 385 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 437
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 17/184 (9%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+PSP I W E + + ++ + + + +L + + C A H + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKR-VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 225
Query: 270 ----------ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
R E P YP+ + + L+ G PTP I W G
Sbjct: 226 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 285
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DP 376
+ D+ + K L+I + D GEY A N +G V V A P D
Sbjct: 286 D-LPSDKAKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 342
Query: 377 PRNV 380
P+N+
Sbjct: 343 PKNL 346
Score = 37.1 bits (82), Expect = 0.34
Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 350 EYQIQAKNIIG---EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
E ++QA+N G E + + P PR V + +++ L+W+ P G +G
Sbjct: 798 EIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG 857
Query: 407 NYIVEYYR-TGWNVWLKAITSRKTNVTLFDLIEG---SEYKFRIKAESPYGMSAPSSESS 462
Y ++Y G V + + + N T F + S Y+F + A + G +E S
Sbjct: 858 -YTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEES 916
Query: 463 P 463
P
Sbjct: 917 P 917
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 64.1 bits (149), Expect = 3e-09
Identities = 75/305 (24%), Positives = 117/305 (38%), Gaps = 30/305 (9%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLL 243
P + R + + + ++ F G P PT+ WFK+ S+ L
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG--SNLDGGNYHVYENGSLE 487
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D+G C ATN G A + R LE R R ED + T+ L+
Sbjct: 488 IKMIRKEDQGIYTCVATNILGKAENQVR--LEVKDPTRIYRMPEDQVARR-GTTVQLECR 544
Query: 304 IVGKPT--PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
+ P+ T+ W D P+ +R++ + L I D+G Y A + +
Sbjct: 545 VKHDPSLKLTVSWLKDDEPLYIGNRMK----KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 362 DTAAFLVTVTAP---------------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG 406
D A +TV A PD PR++ +T ++SV L W P D +
Sbjct: 601 DLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTW-IPGDANNSPIT 659
Query: 407 NYIVEYYRTGW--NVWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSP 463
+Y+V++ + VW + N + L Y+FR+ A + G S PS S
Sbjct: 660 DYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSER 719
Query: 464 VRIPG 468
R G
Sbjct: 720 YRTSG 724
Score = 48.4 bits (110), Expect = 1e-04
Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+P IAW+K ++ S + + L + D GE C A+N+ G
Sbjct: 271 SGVPTPDIAWYKKGGDLPSDK---AKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRH 327
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ ++AAP Y L+ E L G P PT++W +G P+ +
Sbjct: 328 TISVRVKAAP---YWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNP 384
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPD--PPRN 379
+++ + S R YQ N G A AF+ + PP PRN
Sbjct: 385 NREVAGDTII-FRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRN 437
Score = 43.6 bits (98), Expect = 0.004
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 17/184 (9%)
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G+PSP I W E + + ++ + + + +L + + C A H + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKR-VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQ 225
Query: 270 ----------ARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
R E P YP+ + + L+ G PTP I W G
Sbjct: 226 KNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG 285
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP---DP 376
+ D+ + K L+I + D GEY A N +G V V A P D
Sbjct: 286 D-LPSDKAKFENFNK--ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDE 342
Query: 377 PRNV 380
P+N+
Sbjct: 343 PKNL 346
Score = 35.9 bits (79), Expect = 0.78
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR-TGWNVWLKAITSRKTNVT 432
P PR V + +++ L+W+ P G +G Y ++Y G V + + + N T
Sbjct: 932 PSAPRRFRVRQPNLETINLEWDHPEHPNGIMIG-YTLKYVAFNGTKVGKQIVENFSPNQT 990
Query: 433 LFDLIEG---SEYKFRIKAESPYGMSAPSSESSP 463
F + S Y+F + A + G +E SP
Sbjct: 991 KFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESP 1024
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 18/198 (9%)
Query: 182 QEPPVFIKRLEDVT-ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
Q PV +K L V A+ ++V SGIP PTI W K+ + + T +
Sbjct: 76 QASPV-VKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLR 134
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINET--- 297
+ P D G C A N G A+ K RL ++ P + E+G L +++ T
Sbjct: 135 IA---HASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVI------ENG-LPDLSTTEGS 184
Query: 298 -IFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
FL G P P I W DG P ++ + +I P +L + + + D G Y A+
Sbjct: 185 HAFLPCKARGSPEPNITWDKDGQP-VSGAEGKFTIQPSGELL-VKNLEGQDAGTYTCTAE 242
Query: 357 NIIGEDTAAFLVTVTAPP 374
N +G +T+ P
Sbjct: 243 NAVGRARRRVHLTILVLP 260
Score = 59.3 bits (137), Expect = 7e-08
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 8/166 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
+GIP+PT++W K ++ +R + S L Q LP G C+A N G A
Sbjct: 12 TGIPAPTVSWSKAGAQL-GARGSGYRVSPS-GALEIGQALPIHAGRYTCSARNSAGVAHK 69
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
L ++A+P ++ P + E E + L G P PTI W+ +G + T +
Sbjct: 70 HVFLTVQASPVVK-PLPSVVRAVAE--EEVLLPCEASGIPRPTITWQKEGLNVATG--VS 124
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+ P L+I A D G Y AKN G + V PP
Sbjct: 125 TQVLPG-GQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPP 169
Score = 50.4 bits (115), Expect = 3e-05
Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 5/140 (3%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
Q PPV L D++ E G P P I W KD + S T + +
Sbjct: 166 QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGE 223
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
LL + D G CTA N G A + L + P + D L + + ++L+
Sbjct: 224 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPV--FTTLPGDRSL-RLGDRLWLR 280
Query: 302 TTIVGKPTPTIEWRHDGHPI 321
G PTP I W + P+
Sbjct: 281 CAARGSPTPRIGWTVNDRPV 300
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 63.7 bits (148), Expect = 3e-09
Identities = 71/296 (23%), Positives = 115/296 (38%), Gaps = 21/296 (7%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFK--DDYEIFSSR-----RTAITTDESTS 240
I +L++ T EN +V G P P I W + D + R + +S
Sbjct: 304 IIQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSS 363
Query: 241 VLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L + S G C A +R GGH + L +E APK + +E N I
Sbjct: 364 SLHIKDVKLSGSGRYDCEAASRIGGHQKSMY-LDIEYAPK--FISNQTIYYSWEGNP-IN 419
Query: 300 LKTTIVGKPTPTIEWRHDGH--PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ + P +I WR D P ++ T + +L+I +D G Y A N
Sbjct: 420 ISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATN 479
Query: 358 IIGEDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW 417
IG +++ + P P V + + + + P GG + +Y V+
Sbjct: 480 HIGTRFQEYILALADVPSSPYGVKIIELSQTTAKVSFNKPDSHGGVPIHHYQVDVKEVAS 539
Query: 418 NVWLKAITSR--KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS----ESSPVRIP 467
+W K + S +T V L +L + Y+ R+ A + G S ++ PVR P
Sbjct: 540 EIW-KIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQGDYSKIEIFQTLPVREP 594
Score = 60.1 bits (139), Expect = 4e-08
Identities = 52/189 (27%), Positives = 79/189 (41%), Gaps = 13/189 (6%)
Query: 193 DVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDE 252
+ TA +++ F SG P P I+WF++ I + + + S + L I+ SD
Sbjct: 219 NATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYIL--KGSNTELTVRNIINSDG 276
Query: 253 GEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
G C ATN+ G +A L + P + Q ++ YE N + L G+P P I
Sbjct: 277 GPYVCRATNKAGEDEKQAFLQVFVQPHI---IQLKNETTYE-NGQVTLVCDAEGEPIPEI 332
Query: 313 EWRH--DGHPII-----TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
W+ DG D RIE+ S L I K S G Y +A + IG +
Sbjct: 333 TWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKS 392
Query: 366 FLVTVTAPP 374
+ + P
Sbjct: 393 MYLDIEYAP 401
Score = 47.2 bits (107), Expect = 3e-04
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
P P + I+ + A P +H GG P+ YQV+ + S W + ++
Sbjct: 496 PSSPYGVKIIELSQTTAKVSFNKPDSH-GGVPIHHYQVDVKEVASEIW-KIVRSHGVQTM 553
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSEL 169
+VL LEP Y+ RVAA+N G +YS++
Sbjct: 554 VVLNNLEPNTTYEIRVAAVNGKGQGDYSKI 583
Score = 44.8 bits (101), Expect = 0.002
Identities = 43/181 (23%), Positives = 71/181 (39%), Gaps = 11/181 (6%)
Query: 198 ENDKVEFHVTFSGIPSPTIAWFKDDYEI--FSSRRTAITTDESTSVLLFHQILPSDEGEI 255
+ + E S P+P ++W + E+ S R A+ + + +L I SDEG
Sbjct: 128 QGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQIL---NINKSDEGIY 184
Query: 256 KCTAT--NRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
+C RG + + P + P++ + E E + G P P I
Sbjct: 185 RCEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATA-ERGEEMTFSCRASGSPEPAIS 243
Query: 314 WRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED-TAAFLVTVTA 372
W +G I ++ + + + L + + SD G Y +A N GED AFL
Sbjct: 244 WFRNGKLI--EENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQ 301
Query: 373 P 373
P
Sbjct: 302 P 302
Score = 43.2 bits (97), Expect = 0.005
Identities = 63/281 (22%), Positives = 109/281 (38%), Gaps = 10/281 (3%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLF 244
P FI + E + + P +I W +D + + T + T ST +
Sbjct: 401 PKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKT-YSTGRKMI 459
Query: 245 HQILPS---DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
+I P+ D G CTATN G + L L P Y + + L + F K
Sbjct: 460 LEIAPTSDNDFGRYNCTATNHIGTRFQEYILALADVPSSPYGVKIIE-LSQTTAKVSFNK 518
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P ++ D + ++ + +++ +++ + + E ++ A N G+
Sbjct: 519 PDSHGG-VPIHHYQVDVKEVASEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAVNGKGQ 577
Query: 362 -DTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWE-PPADDGGCKVGNYIVEY-YRTGWN 418
D + + T P P S+ Q + DDGG + YIV+Y + +
Sbjct: 578 GDYSKIEIFQTLPVREPSPPSIHGQPSSGKSFKLSITKQDDGGAPILEYIVKYRSKDKED 637
Query: 419 VWL-KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPS 458
WL K + K ++ L L KFR+ A + G S P+
Sbjct: 638 QWLEKKVQGNKDHIILEHLQWTMGMKFRLPAANRLGYSEPT 678
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 63.7 bits (148), Expect = 3e-09
Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 26/313 (8%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 433 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 492
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A + L ++ A + +Q E ++ + F
Sbjct: 493 IPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWI--VKQPEYAVVQRGSMVSFEC 548
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 549 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 604
Query: 361 EDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
+A+ +++V AP P+PP ++ +T Q+DKSV L W P DD + +I+
Sbjct: 605 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFII 663
Query: 411 EY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
EY ++ G ++ +T L L Y FR+ A + G S PS S
Sbjct: 664 EYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 722
Query: 467 PGRAIDMDFLAVE 479
D + AVE
Sbjct: 723 KASEPDKNPTAVE 735
Score = 48.8 bits (111), Expect = 1e-04
Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 14/211 (6%)
Query: 172 VLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS 228
V +S+ + + PP F+ + L + + G+P+P I W K+D +
Sbjct: 236 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED-GMLPK 294
Query: 229 RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED 288
RT E T ++ + +D G +C A N G + ++AAP Y
Sbjct: 295 NRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKAAP---YWITAPQ 349
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEISITPKFSVLKIHSAKRSD 347
L+ E L G P P I W +G PI I D I +++ + +RS
Sbjct: 350 NLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-TIIFSNVQERSS 408
Query: 348 RGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
YQ A N G A V V A +PPR
Sbjct: 409 -AVYQCNASNEYGYLLANAFVNVLA--EPPR 436
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 933 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 990
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 991 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1025
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 63.7 bits (148), Expect = 3e-09
Identities = 75/313 (23%), Positives = 119/313 (38%), Gaps = 26/313 (8%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 433 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 492
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A + L ++ A + +Q E ++ + F
Sbjct: 493 IPVAQ--KDSTGTYTCVARNKLGMAKNEVHLEIKDATWI--VKQPEYAVVQRGSMVSFEC 548
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 549 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 604
Query: 361 EDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
+A+ +++V AP P+PP ++ +T Q+DKSV L W P DD + +I+
Sbjct: 605 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFII 663
Query: 411 EY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
EY ++ G ++ +T L L Y FR+ A + G S PS S
Sbjct: 664 EYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 722
Query: 467 PGRAIDMDFLAVE 479
D + AVE
Sbjct: 723 KASEPDKNPTAVE 735
Score = 48.8 bits (111), Expect = 1e-04
Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 14/211 (6%)
Query: 172 VLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSS 228
V +S+ + + PP F+ + L + + G+P+P I W K+D +
Sbjct: 236 VKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED-GMLPK 294
Query: 229 RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYED 288
RT E T ++ + +D G +C A N G + ++AAP Y
Sbjct: 295 NRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTISVRVKAAP---YWITAPQ 349
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEISITPKFSVLKIHSAKRSD 347
L+ E L G P P I W +G PI I D I +++ + +RS
Sbjct: 350 NLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGD-TIIFSNVQERSS 408
Query: 348 RGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
YQ A N G A V V A +PPR
Sbjct: 409 -AVYQCNASNEYGYLLANAFVNVLA--EPPR 436
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 933 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 990
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 991 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1025
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 63.7 bits (148), Expect = 3e-09
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP FI+ E+++ E SG+P+P ++W+ + + S I +++ L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI--NETIFL 300
+F + SD G C A NR G A +L + A R P ++ +++ L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 301 KTTIVGKPTPTIEWRHDGHPI-ITDDRIEI--SITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ I P P + W+ + + DRI + T + ++L I + D G Y + A N
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVN 427
Query: 358 IIGEDTAAFLVTVTAPPD 375
G T + VTA P+
Sbjct: 428 EAGVTTCNTRLDVTARPN 445
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 63.7 bits (148), Expect = 3e-09
Identities = 52/193 (26%), Positives = 77/193 (39%), Gaps = 11/193 (5%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI-FSSRRTAITTDESTS 240
Q PP F +D LE VE+ G P P I W K ++ + T + S+
Sbjct: 416 QAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVL----SSG 471
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEINETIF 299
L + D+G+ +C A + G V K + L PK L Q E+ + I
Sbjct: 472 TLRIDRAAQHDQGQYECQAVSSLG--VKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNIN 529
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
+ G+P P I W +G I + + L I+ A D+G Y+ A+N
Sbjct: 530 ISCHAQGEPQPIITWNKEGVQITESGKFHVD---DEGTLTIYDAGFPDQGRYECVARNSF 586
Query: 360 GEDTAAFLVTVTA 372
G +TVTA
Sbjct: 587 GLAVTNMFLTVTA 599
Score = 57.2 bits (132), Expect = 3e-07
Identities = 68/312 (21%), Positives = 131/312 (41%), Gaps = 24/312 (7%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD-YEIFSSRRTAITTDESTSVLL 243
P F+ + +D L +G P P I W +D+ E+ SR A ++S L
Sbjct: 330 PSFVIQPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVA-----TSSGLY 384
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
I D G C A N G A + ++A P ++ +D ++ E + +L
Sbjct: 385 LQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPP--QFTVTPKDQVVLEEHAVEWL-CE 441
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G P P I W G + + + + + L+I A + D+G+Y+ QA + +G
Sbjct: 442 ADGNPPPVIVWTKTGGQLPVEGQHTVLSS---GTLRIDRAAQHDQGQYECQAVSSLGVKK 498
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVG--NYIVEYYRTGWNVWL 421
+ +TV P+ ++V Q+ + +++ + G I+ + + G +
Sbjct: 499 VSVQLTV-----KPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITE 553
Query: 422 --KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDMDFLAVE 479
K + +T++D + ++ A + +G++ + + I GR DF VE
Sbjct: 554 SGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQAGDDF--VE 611
Query: 480 ARIINEALTRED 491
+ I+ +A+ R D
Sbjct: 612 SSIL-DAVQRVD 622
Score = 54.8 bits (126), Expect = 2e-06
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 10/206 (4%)
Query: 172 VLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRT 231
V +V+ + + + P +DV + V F G P P I W +++ + T
Sbjct: 221 VASVTVEEFNCQSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDT 280
Query: 232 AITT-DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK-ARLCLEAAP-KLRYPRQYED 288
+ D+ T L+ SD+G +C A N G A T+ A L + P K + Q +D
Sbjct: 281 RLNVFDDGT--LMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQD 338
Query: 289 GLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDR 348
+ I + L+ G P P I W D + + D ++ + S L + + + D
Sbjct: 339 TEVL-IGTSTTLECMATGHPHPLITWTRD-NGLELDGSRHVATS---SGLYLQNITQRDH 393
Query: 349 GEYQIQAKNIIGEDTAAFLVTVTAPP 374
G + A N G AA + V APP
Sbjct: 394 GRFTCHANNSHGTVQAAANIIVQAPP 419
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 297 TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK 356
T++ G P P I W H+ H + +D +++ L I + + SD+G YQ A+
Sbjct: 250 TVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDD-GTLMIRNTRESDQGVYQCMAR 308
Query: 357 NIIGE-DTAAFLVTVTAPPDPP 377
N GE T + ++ ++ P P
Sbjct: 309 NSAGEAKTQSAMLRYSSLPAKP 330
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 63.7 bits (148), Expect = 3e-09
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP FI+ E+++ E SG+P+P ++W+ + + S I +++ L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI--NETIFL 300
+F + SD G C A NR G A +L + A R P ++ +++ L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 301 KTTIVGKPTPTIEWRHDGHPI-ITDDRIEI--SITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ I P P + W+ + + DRI + T + ++L I + D G Y + A N
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVN 427
Query: 358 IIGEDTAAFLVTVTAPPD 375
G T + VTA P+
Sbjct: 428 EAGVTTCNTRLDVTARPN 445
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein
protein.
Length = 498
Score = 63.7 bits (148), Expect = 3e-09
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 7/198 (3%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR-RTAITTDESTSVL 242
PP FI+ E+++ E SG+P+P ++W+ + + S I +++ L
Sbjct: 249 PPRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSL 308
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEI--NETIFL 300
+F + SD G C A NR G A +L + A R P ++ +++ L
Sbjct: 309 IFEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHKRAPMFIYKPQSKKVLEGDSVKL 368
Query: 301 KTTIVGKPTPTIEWRHDGHPI-ITDDRIEI--SITPKFSVLKIHSAKRSDRGEYQIQAKN 357
+ I P P + W+ + + DRI + T + ++L I + D G Y + A N
Sbjct: 369 ECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLL-IKDVNKKDAGWYTVSAVN 427
Query: 358 IIGEDTAAFLVTVTAPPD 375
G T + VTA P+
Sbjct: 428 EAGVTTCNTRLDVTARPN 445
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 63.3 bits (147), Expect = 5e-09
Identities = 76/313 (24%), Positives = 117/313 (37%), Gaps = 26/313 (8%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 452 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 511
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A K + LE +Q E ++ + F
Sbjct: 512 IPVAQ--KDSTGTYTCVARNKLGMA--KNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 567
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 568 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 623
Query: 361 EDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
+A+ +++V AP P+PP ++ +T Q+DKSV L W P DD + +I+
Sbjct: 624 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFII 682
Query: 411 EY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
EY ++ G ++ +T L L Y FR+ A + G S PS S
Sbjct: 683 EYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
Query: 467 PGRAIDMDFLAVE 479
D + AVE
Sbjct: 742 KASEPDKNPTAVE 754
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSG 210
+V +++++ + + LSD + + + PP F+ + L + + G
Sbjct: 237 KVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG 296
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
+P+P I W K+D + RT E T ++ + +D G +C A N G
Sbjct: 297 LPTPIIYWAKED-GMLPKNRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTI 353
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEI 329
+ ++AAP Y L+ E L G P P I W +G PI I D
Sbjct: 354 SVRVKAAP---YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 410
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
I +++ + +RS YQ A N G A V V A +PPR
Sbjct: 411 KIDGD-TIIFSNVQERSS-AVYQCNASNEYGYLLANAFVNVLA--EPPR 455
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 952 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 1009
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1044
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 63.3 bits (147), Expect = 5e-09
Identities = 76/313 (24%), Positives = 117/313 (37%), Gaps = 26/313 (8%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
EPP + + + N F G P PTI WFK + + T
Sbjct: 452 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 511
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF-L 300
+ Q G C A N+ G A K + LE +Q E ++ + F
Sbjct: 512 IPVAQ--KDSTGTYTCVARNKLGMA--KNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 567
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
K + T+ W D + +D+R + L + D G Y A +
Sbjct: 568 KVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTCVANTTLD 623
Query: 361 EDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIV 410
+A+ +++V AP P+PP ++ +T Q+DKSV L W P DD + +I+
Sbjct: 624 SVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNSPITKFII 682
Query: 411 EY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
EY ++ G ++ +T L L Y FR+ A + G S PS S
Sbjct: 683 EYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSEASEQYLT 741
Query: 467 PGRAIDMDFLAVE 479
D + AVE
Sbjct: 742 KASEPDKNPTAVE 754
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSG 210
+V +++++ + + LSD + + + PP F+ + L + + G
Sbjct: 237 KVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG 296
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
+P+P I W K+D + RT E T ++ + +D G +C A N G
Sbjct: 297 LPTPIIYWAKED-GMLPKNRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTI 353
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEI 329
+ ++AAP Y L+ E L G P P I W +G PI I D
Sbjct: 354 SVRVKAAP---YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 410
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
I +++ + +RS YQ A N G A V V A +PPR
Sbjct: 411 KIDGD-TIIFSNVQERSS-AVYQCNASNEYGYLLANAFVNVLA--EPPR 455
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 952 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 1009
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1044
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 62.9 bits (146), Expect = 6e-09
Identities = 51/197 (25%), Positives = 77/197 (39%), Gaps = 5/197 (2%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDE--ST 239
++P + K + V+ F +G P P + W K + T I E
Sbjct: 1851 EKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN 1910
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L+ ++ D G+ CTA+N G L + Y+D +Y + +TI
Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVY-LGDTIA 1969
Query: 300 LKTTIVGKPTPTIEWRHDGHPII-TDDRIEISIT-PKFSVLKIHSAKRSDRGEYQIQAKN 357
++ G P P I W + T +E IT + L I A SDRG Y+ A N
Sbjct: 1970 MECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYKCVASN 2029
Query: 358 IIGEDTAAFLVTVTAPP 374
G D+ A + V A P
Sbjct: 2030 AAGADSLAIRLHVAALP 2046
Score = 59.3 bits (137), Expect = 7e-08
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 9/185 (4%)
Query: 182 QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDD---YEIFSSRRTAITTDES 238
Q+P + +DVT D + G P+P I+W D ++ S + IT E+
Sbjct: 1948 QQPQILASHYQDVTVYLGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHEN 2007
Query: 239 TSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETI 298
+ L + SD G KC A+N G RL + A P + + + E+ + +I
Sbjct: 2008 RT-LSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAALPPVIHQEKLEN-ISLPPGLSI 2065
Query: 299 FLKTTIVGKPTPTIEW-RHDGHPIITDDRI--EISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ T P P++ W DG I + + + P L I + D G Y+ A
Sbjct: 2066 HIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPN-GTLYIRNLAPKDSGRYECVA 2124
Query: 356 KNIIG 360
N++G
Sbjct: 2125 ANLVG 2129
Score = 53.6 bits (123), Expect = 4e-06
Identities = 41/174 (23%), Positives = 72/174 (41%), Gaps = 10/174 (5%)
Query: 209 SGIPSPTIAWFKDDYEIFSS--------RRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
+G+P+P I+W D + +S RT + L F+++ +EG+ C A
Sbjct: 2268 TGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAE 2327
Query: 261 NRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHP 320
N+ G + R+ + AP + Y + + + + G+P P + W +
Sbjct: 2328 NQVGKDEMRVRVKVVTAPATIRNKTYL-AVQVPYGDVVTVACEAKGEPMPKVTWLSPTNK 2386
Query: 321 IITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
+I + I ++L I A+RSD G Y +N GED + V P
Sbjct: 2387 VIPTSSEKYQIYQDGTLL-IQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQP 2439
Score = 52.8 bits (121), Expect = 6e-06
Identities = 51/213 (23%), Positives = 80/213 (37%), Gaps = 11/213 (5%)
Query: 170 SDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSS 228
+D L + A+ P + ++LE+++ + H T P P++ W D +I S
Sbjct: 2033 ADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPS 2092
Query: 229 R-RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLE-AAPKLRYPRQY 286
+ L + P D G +C A N G A +L ++ AA R
Sbjct: 2093 QFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAAANARITGTS 2152
Query: 287 EDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIIT-----DDRIEISITPKFSVLKIH 341
T+ L + G P P I WR +I D RI++ L +
Sbjct: 2153 PRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFAN---GTLVVK 2209
Query: 342 SAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
S D G+Y A+N +G+D V V P
Sbjct: 2210 SVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKP 2242
Score = 45.6 bits (103), Expect = 0.001
Identities = 43/196 (21%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 183 EPPVFIKRL-EDVTALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDESTS 240
E P+F + E +TA+ + + + +G P+P++ W + ++ S ++ ++
Sbjct: 2540 EKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADG 2599
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
+L + D G +C A N GH T+ + L+ K +QY + + ET+ L
Sbjct: 2600 MLHISGLSSVDAGAYRCVARNAAGH--TERLVSLKVGLKPEANKQYHNLVSIINGETLKL 2657
Query: 301 KTTIVGKPTPTIEWR-HDGHPIITDDRI-EISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
T G W +G + + +S+ L + A DRG Y + +
Sbjct: 2658 PCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDN-GTLTVREASVFDRGTYVCRMETE 2716
Query: 359 IGEDTAAFLVTVTAPP 374
G + V V A P
Sbjct: 2717 YGPSVTSIPVIVIAYP 2732
Score = 45.2 bits (102), Expect = 0.001
Identities = 39/169 (23%), Positives = 65/169 (38%), Gaps = 3/169 (1%)
Query: 210 GIPSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
GIP+P + W F + + + T L + SD ++ C A N GG A
Sbjct: 2470 GIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARL 2529
Query: 269 KARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEW-RHDGHPIITDDR 326
+L LE K + + + TI L + G PTP++ W +G + + +
Sbjct: 2530 IVQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQ 2589
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
++ +L I D G Y+ A+N G + V P+
Sbjct: 2590 LQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPE 2638
Score = 34.3 bits (75), Expect = 2.4
Identities = 38/183 (20%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDE--STSVLLFHQILPSDEGEIKCTATNRGG-- 264
SG P P I W + + + + + + L+ + D G+ C A N+ G
Sbjct: 2171 SGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGDD 2230
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPII-- 322
+ V K + ++ A K+ + + + + Y + + G P P I W ++
Sbjct: 2231 YVVLKVDVVMKPA-KIEHKEENDHKVFY--GGDLKVDCVATGLPNPEISWSLPDGSLVNS 2287
Query: 323 ---TDD---RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDP 376
+DD R + + L + + G+Y A+N +G+D V V P
Sbjct: 2288 FMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPAT 2347
Query: 377 PRN 379
RN
Sbjct: 2348 IRN 2350
Score = 32.7 bits (71), Expect = 7.3
Identities = 45/194 (23%), Positives = 71/194 (36%), Gaps = 9/194 (4%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES---T 239
EP ++R D T LE + SP+I W D I + + S +
Sbjct: 480 EPSGAVQR--DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSS 537
Query: 240 SVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIF 299
L + PSD G +C A R R+ +++ P + + + E++
Sbjct: 538 GWLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQS-PSTQPAEKDTVTIGKNPGESVT 596
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITD--DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKN 357
L + P + W II D + + + P L I + SD G Y+ A N
Sbjct: 597 LPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPN-GTLSIPKVQVSDSGYYRCVAVN 655
Query: 358 IIGEDTAAFLVTVT 371
G D +TVT
Sbjct: 656 QQGADHFTVGITVT 669
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 62.5 bits (145), Expect = 8e-09
Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 20/229 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
KYQ V N G SNYS+ + LTV+ E P F+K D+T
Sbjct: 577 KYQCIVT--NHFG-SNYSQKAK-LTVN------EMPSFLKTPMDLTIRTGAMARLECAAE 626
Query: 210 GIPSPTIAWFKD---DYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G P+P I+W KD D+ RR + ++ V + D G C A N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPED--DVFFIANVKIEDMGIYSCMAQNTAGGL 684
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A L + P + R ED + ET L+ G P P + W D P++ +R
Sbjct: 685 SANASLTVLETPS--FIRPLEDKTVTR-GETAVLQCIAGGSPAPRLNWTKDDGPLLVTER 741
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ + +L I A D G+Y N +G + + V + P+
Sbjct: 742 HFFAAANQ--LLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPN 788
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 14/156 (8%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEI 294
E TS+L + +DEG+ +C TN G + KA+L + P L+ P L
Sbjct: 560 EYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMD----LTIRT 615
Query: 295 NETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
L+ G P P I W+ DG P + R+ + P+ V I + K D G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH--VMPEDDVFFIANVKIEDMGIY 673
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPD---PPRNVSVTR 384
A+N G +A +TV P P + +VTR
Sbjct: 674 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTR 709
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 62.5 bits (145), Expect = 8e-09
Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 20/229 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
KYQ V N G SNYS+ + LTV+ E P F+K D+T
Sbjct: 577 KYQCIVT--NHFG-SNYSQKAK-LTVN------EMPSFLKTPMDLTIRTGAMARLECAAE 626
Query: 210 GIPSPTIAWFKD---DYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G P+P I+W KD D+ RR + ++ V + D G C A N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPED--DVFFIANVKIEDMGIYSCMAQNTAGGL 684
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A L + P + R ED + ET L+ G P P + W D P++ +R
Sbjct: 685 SANASLTVLETPS--FIRPLEDKTVTR-GETAVLQCIAGGSPAPRLNWTKDDGPLLVTER 741
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ + +L I A D G+Y N +G + + V + P+
Sbjct: 742 HFFAAANQ--LLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPN 788
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 14/156 (8%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEI 294
E TS+L + +DEG+ +C TN G + KA+L + P L+ P L
Sbjct: 560 EYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMD----LTIRT 615
Query: 295 NETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
L+ G P P I W+ DG P + R+ + P+ V I + K D G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH--VMPEDDVFFIANVKIEDMGIY 673
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPD---PPRNVSVTR 384
A+N G +A +TV P P + +VTR
Sbjct: 674 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTR 709
>BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein.
Length = 1329
Score = 62.5 bits (145), Expect = 8e-09
Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW-IRTAPPI 134
RP PP +P + D ++ L W P + DG +P+R Y ++ L S W + +A
Sbjct: 575 RPQPPSRPMVQQ--EDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVS 631
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
++ L+P Y+FRV A ND+G S +SE S+ LT + P +
Sbjct: 632 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 683
Score = 41.1 bits (92), Expect = 0.021
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 338 LKIHSAKRSDRGEYQIQAKNII-GEDTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWE 395
LK+ ++I+AK G + A + T P P V + + ++ + W
Sbjct: 943 LKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS 1002
Query: 396 PPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTNVTL-FDLIE-GSEYKFRIKAES 450
D G + Y++E + W++ +K I ++ T D+++ G Y FR+ A +
Sbjct: 1003 S-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 1061
Query: 451 PYGMSAPSSESSPV 464
YG PSS S V
Sbjct: 1062 DYGFGTPSSPSQSV 1075
Score = 39.5 bits (88), Expect = 0.063
Identities = 39/120 (32%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP- 138
PG P I + + ++ L W P G L YQ+ +RL +T TA VL P
Sbjct: 477 PGPPMGI-LFPEVRTTSVRLIWQPPAAPNGIIL-AYQIT-HRLNTTT-ANTATVEVLAPS 532
Query: 139 --ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ TGL+P Y FR+ A G +E V T DR Q P + + EDV A
Sbjct: 533 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRA 591
Score = 39.1 bits (87), Expect = 0.084
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 9/99 (9%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW---IRTA 131
G P PPG P I+ S AI + W+ G P+ Y +E W I+
Sbjct: 980 GAPGPPGVPIIVRYSS-----AIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 1033
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
P V + L+P Y FRV A+ND G S S
Sbjct: 1034 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 1072
Score = 37.5 bits (83), Expect = 0.26
Identities = 35/109 (32%), Positives = 47/109 (43%), Gaps = 8/109 (7%)
Query: 360 GEDTAAFLVTVTAP--PDPPRNVSVTRQV--DKSVTLDWEPPADDGGCKVGNYIVEYYRT 415
GE A +VT P PP V ++ +SV L WEP DG V Y ++
Sbjct: 560 GEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYTIQTREL 618
Query: 416 GWNVWLKAITSRKTNVTLF--DLIEG-SEYKFRIKAESPYGMSAPSSES 461
W S N + F D ++ + YKFR+KA + G S S ES
Sbjct: 619 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 667
Score = 36.7 bits (81), Expect = 0.45
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
Query: 350 EYQIQAKNIIGE----DTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWEPPADD 400
+++++A N IG+ + + L T+ A PD P +SVT SV + W+PPA+D
Sbjct: 649 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAED 704
Score = 35.1 bits (77), Expect = 1.4
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SR 427
T A P P +V + SV + WE P G G +V + + K +T
Sbjct: 876 TQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDV 935
Query: 428 KTNVTLF----DLIEGSEYKFRIKAES-PYGMSAPSSESSPVRIPG 468
K N L+ DL EG Y+FRI+A++ YG P E++ PG
Sbjct: 936 KGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG---PEIEANVTTGPG 978
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 62.5 bits (145), Expect = 8e-09
Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 20/229 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
KYQ V N G SNYS+ + LTV+ E P F+K D+T
Sbjct: 577 KYQCIVT--NHFG-SNYSQKAK-LTVN------EMPSFLKTPMDLTIRTGAMARLECAAE 626
Query: 210 GIPSPTIAWFKD---DYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G P+P I+W KD D+ RR + ++ V + D G C A N G
Sbjct: 627 GHPAPQISWQKDGGTDFPAARERRMHVMPED--DVFFIANVKIEDMGIYSCMAQNTAGGL 684
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A L + P + R ED + ET L+ G P P + W D P++ +R
Sbjct: 685 SANASLTVLETPS--FIRPLEDKTVTR-GETAVLQCIAGGSPAPRLNWTKDDGPLLVTER 741
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ + +L I A D G+Y N +G + + V + P+
Sbjct: 742 HFFAAANQ--LLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPN 788
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 14/156 (8%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEI 294
E TS+L + +DEG+ +C TN G + KA+L + P L+ P L
Sbjct: 560 EYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMD----LTIRT 615
Query: 295 NETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
L+ G P P I W+ DG P + R+ + P+ V I + K D G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH--VMPEDDVFFIANVKIEDMGIY 673
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPD---PPRNVSVTR 384
A+N G +A +TV P P + +VTR
Sbjct: 674 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTR 709
>AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein
protein.
Length = 1185
Score = 62.5 bits (145), Expect = 8e-09
Identities = 35/112 (31%), Positives = 55/112 (49%), Gaps = 4/112 (3%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW-IRTAPPI 134
RP PP +P + D ++ L W P + DG +P+R Y ++ L S W + +A
Sbjct: 368 RPQPPSRPMVQQ--EDVRARSVLLSWEPGS-DGLSPVRYYTIQTRELPSGRWALHSASVS 424
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPV 186
++ L+P Y+FRV A ND+G S +SE S+ LT + P +
Sbjct: 425 HNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTI 476
Score = 41.1 bits (92), Expect = 0.021
Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 338 LKIHSAKRSDRGEYQIQAKNII-GEDTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWE 395
LK+ ++I+AK G + A + T P P V + + ++ + W
Sbjct: 755 LKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS 814
Query: 396 PPADDGGCKVGNYIVEYYRTG---WNVWLKAITSRKTNVTL-FDLIE-GSEYKFRIKAES 450
D G + Y++E + W++ +K I ++ T D+++ G Y FR+ A +
Sbjct: 815 S-GDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVN 873
Query: 451 PYGMSAPSSESSPV 464
YG PSS S V
Sbjct: 874 DYGFGTPSSPSQSV 887
Score = 40.3 bits (90), Expect = 0.036
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 8/115 (6%)
Query: 354 QAKNIIGEDTAAFLVTVTAP--PDPPRNVSVTRQV--DKSVTLDWEPPADDGGCKVGNYI 409
Q + + GE A +VT P PP V ++ +SV L WEP DG V Y
Sbjct: 347 QTRKVWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEP-GSDGLSPVRYYT 405
Query: 410 VEYYRTGWNVWLKAITSRKTNVTLF--DLIEG-SEYKFRIKAESPYGMSAPSSES 461
++ W S N + F D ++ + YKFR+KA + G S S ES
Sbjct: 406 IQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 460
Score = 39.1 bits (87), Expect = 0.084
Identities = 31/99 (31%), Positives = 40/99 (40%), Gaps = 9/99 (9%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEW---IRTA 131
G P PPG P I+ S AI + W+ G P+ Y +E W I+
Sbjct: 792 GAPGPPGVPIIVRYSS-----AIAIHWSSGD-PGKGPITRYVIEARPSDEGLWDILIKDI 845
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELS 170
P V + L+P Y FRV A+ND G S S
Sbjct: 846 PKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPS 884
Score = 36.7 bits (81), Expect = 0.45
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 5/56 (8%)
Query: 350 EYQIQAKNIIGE----DTAAFLVTVTAPPDP-PRNVSVTRQVDKSVTLDWEPPADD 400
+++++A N IG+ + + L T+ A PD P +SVT SV + W+PPA+D
Sbjct: 442 KFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAED 497
Score = 35.9 bits (79), Expect = 0.78
Identities = 38/120 (31%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRP- 138
PG P I + + ++ L W P G L YQ+ +RL +T TA VL P
Sbjct: 270 PGPPMGI-LFPEVRTTSVRLIWQPPAAPNGIIL-AYQIT-HRLNTTT-ANTATVEVLAPS 325
Query: 139 --ELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
+ TGL+P Y FR+ A +E V T DR Q P + + EDV A
Sbjct: 326 ARQYTATGLKPESVYLFRITAQTRKVWGEAAEALVVTTEKRDR-PQPPSRPMVQQEDVRA 384
Score = 35.1 bits (77), Expect = 1.4
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAIT-SR 427
T A P P +V + SV + WE P G G +V + + K +T
Sbjct: 688 TQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDV 747
Query: 428 KTNVTLF----DLIEGSEYKFRIKAES-PYGMSAPSSESSPVRIPG 468
K N L+ DL EG Y+FRI+A++ YG P E++ PG
Sbjct: 748 KGNSPLWLKVKDLAEGVTYRFRIRAKTFTYG---PEIEANVTTGPG 790
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 1184 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 1243
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 1244 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 1301
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 1302 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 1361
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 1362 VNDPQREDSGLYICKAENMLGESTCA 1387
Score = 58.4 bits (135), Expect = 1e-07
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 13/216 (6%)
Query: 164 SNYSELSDVLTVSSDRAS-----QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
S+ S +V TV A ++ P+ L D + E D V H+T S + + W
Sbjct: 1944 SSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIV--HLTTSITNAKEVNW 2001
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEIKCTATNRGGHAVTKARLCL--E 275
+ ++ + S + D++T L+ ++ D +GE C A N G T A+L +
Sbjct: 2002 YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 2061
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAP ++ R+ E L + I P +W G I D+ I +
Sbjct: 2062 AAPVIK--RKIEP-LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 2118
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
S L+I + D GEY +A N G + +TVT
Sbjct: 2119 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 2154
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/196 (26%), Positives = 81/196 (41%), Gaps = 14/196 (7%)
Query: 176 SSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITT 235
+S R E IK+ +DVTALEN V F V+ S P + WF + EI S + + +
Sbjct: 342 ASARLHVETVKIIKKPKDVTALENATVAFEVSVSHDTVP-VKWFHKNVEIKPSDKHRLVS 400
Query: 236 DESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN 295
+ L+ I PSD GE G KA+L +E + + E
Sbjct: 401 ERKVHKLMLQNISPSDAGEYTAVV----GQLECKAKLFVETLHITKTMKNIE----VPET 452
Query: 296 ETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+T + + P++ W +G I ++ +I + K L I + D EY
Sbjct: 453 KTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF-- 509
Query: 356 KNIIGEDTAAFLVTVT 371
+ G D + +TVT
Sbjct: 510 --VCGNDQVSATLTVT 523
Score = 55.6 bits (128), Expect = 9e-07
Identities = 52/225 (23%), Positives = 86/225 (38%), Gaps = 12/225 (5%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
EPP ++ L+ VT F SG P P I+W+K++ + + + D L
Sbjct: 793 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 852
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQ----YEDGLLYEINETI 298
L + P D C A N G A T A L +E P++ P Q Y ++ + +T+
Sbjct: 853 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVE-VPEVVSPDQEMPVYPPAIITPLQDTV 911
Query: 299 FLK------TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQ 352
+ V + W I ++ L+I A D G Y
Sbjct: 912 TSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 971
Query: 353 IQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTR-QVDKSVTLDWEP 396
A N +G+ ++ +++ N S ++ V SV+ EP
Sbjct: 972 FVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEP 1016
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 12/174 (6%)
Query: 184 PPVFIKRLEDVTALENDKVEFHVT--FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV 241
P + L+D+ A E D + F VT + GI + W K+ EI S+ + + T + T
Sbjct: 524 PIMITSMLKDINAEEKDTITFEVTVNYEGI---SYKWLKNGVEIKSTDKCQMRTKKLTHS 580
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
L + D + A G A + A L +EA + + + +D + E +F
Sbjct: 581 LNIRNVHFGDAADYTFVA----GKATSTATLYVEAR-HIEFRKHIKDIKVLEKKRAMF-- 633
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
V +P T++W D + DRI+I L I S + SD G+Y + A
Sbjct: 634 ECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVA 687
Score = 52.8 bits (121), Expect = 6e-06
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 3/117 (2%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDEST--S 240
+ P FI+ L + + V FH SGIP P I WF + I ++ +EST +
Sbjct: 1019 QKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMA 1078
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCL-EAAPKLRYPRQYEDGLLYEINE 296
++L G+ C A N G A A L + AP+ + E + E+ E
Sbjct: 1079 LMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKE 1135
Score = 47.2 bits (107), Expect = 3e-04
Identities = 41/144 (28%), Positives = 53/144 (36%), Gaps = 5/144 (3%)
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE----PPVFIKRLEDVT 195
L+L P + A ND G + S V QE PP I L+D
Sbjct: 852 LLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTV 911
Query: 196 ALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEI 255
E F SG ++W+ D +I SR +T E T L + P DEG
Sbjct: 912 TSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTY 970
Query: 256 KCTATNRGGHAVTKARLCLEAAPK 279
A+N G + A L LE K
Sbjct: 971 TFVASNAVGQVSSTANLSLEGFSK 994
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 1279 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 1338
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 1339 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 1390
Score = 41.1 bits (92), Expect = 0.021
Identities = 63/266 (23%), Positives = 96/266 (36%), Gaps = 13/266 (4%)
Query: 181 SQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTS 240
S E I+ L D+T E V F V S + W D EI S + I
Sbjct: 85 SVEKIKIIRGLRDLTCTETQNVVFEVELSH-SGIDVLWNFKDKEIKPSSKYKIEAHGKIY 143
Query: 241 VLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFL 300
L ++ DEG+ T G +T +L + A + P D + E E +F
Sbjct: 144 KLTVLNMMKDDEGKY----TFYAGENITSGKLTV-AGGAISKP--LTDQTVAESQEAVF- 195
Query: 301 KTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
V P EW DG + + I L I + K D GEY K
Sbjct: 196 -ECEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTY--KVATS 252
Query: 361 EDTAAFLVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVW 420
+ +A V +N++VT D T++ P G + N +V + +
Sbjct: 253 KTSAKLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAIS 312
Query: 421 LKAITSRKTNVTLFDLIEGSEYKFRI 446
+K T + +++ S Y FR+
Sbjct: 313 VKG-TIYSLRIKNCAIVDESVYGFRL 337
Score = 39.9 bits (89), Expect = 0.048
Identities = 34/124 (27%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H+ ++ ALND G + S LTV A PV +++E + +F
Sbjct: 2035 HQGEYVCEALNDSGKT---ATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEI 2087
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
P+ WFK EI+ S + +I + + S L + D GE C A+N G
Sbjct: 2088 QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 2147
Query: 269 KARL 272
A L
Sbjct: 2148 TATL 2151
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 1203 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 1262
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 1263 GKTICSAYLKINSKGEGHKDTETESAVAKSL 1293
Score = 32.3 bits (70), Expect = 9.6
Identities = 35/168 (20%), Positives = 58/168 (34%), Gaps = 9/168 (5%)
Query: 188 IKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQI 247
I L+DV +E K S ++ W+ +D +I R + L+ ++
Sbjct: 4 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRT 63
Query: 248 LPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGK 307
SDEG K G T L +E K++ R D E +F +
Sbjct: 64 HASDEGPYKLIV----GRVETNCNLSVE---KIKIIRGLRDLTCTETQNVVF--EVELSH 114
Query: 308 PTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQA 355
+ W I + +I K L + + + D G+Y A
Sbjct: 115 SGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA 162
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 109 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 166
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 167 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 226
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 227 VNDPQREDSGLYICKAENMLGESTCA 252
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 144 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 203
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 204 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255
Score = 37.5 bits (83), Expect = 0.26
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 8/115 (6%)
Query: 164 SNYSELSDVLTVSSDRAS-----QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
S+ S +V TV A ++ P+ L D + E D V H+T S + + W
Sbjct: 809 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV--HLTTSITNAKEVNW 866
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEIKCTATNRGGHAVTKARL 272
+ ++ + S + D++T L+ ++ D +GE C A N G T A+L
Sbjct: 867 YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 921
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 68 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 127
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 128 GKTICSAYLKINSKGEGHKDTETESAVAKSL 158
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 62.5 bits (145), Expect = 8e-09
Identities = 53/206 (25%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSR--RTAITTDESTSVL 242
P+FIK + + D VT GIP P I WF + + S + D+ + ++
Sbjct: 49 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 108
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINE------ 296
LF ++ DEGE C A+N G + A L + + + + E + + +
Sbjct: 109 LFTKL--EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCP 166
Query: 297 TIFLKT----------------TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFS-VLK 339
FLK T+VG+P PT+ W + + T I P S
Sbjct: 167 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 226
Query: 340 IHSAKRSDRGEYQIQAKNIIGEDTAA 365
++ +R D G Y +A+N++GE T A
Sbjct: 227 VNDPQREDSGLYICKAENMLGESTCA 252
Score = 58.4 bits (135), Expect = 1e-07
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 13/216 (6%)
Query: 164 SNYSELSDVLTVSSDRAS-----QEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAW 218
S+ S +V TV A ++ P+ L D + E D V H+T S + + W
Sbjct: 809 SSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIV--HLTTSITNAKEVNW 866
Query: 219 FKDDYEIFSSRRTAITTDESTSVLLFHQILPSD-EGEIKCTATNRGGHAVTKARLCL--E 275
+ ++ + S + D++T L+ ++ D +GE C A N G T A+L +
Sbjct: 867 YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR 926
Query: 276 AAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKF 335
AAP ++ R+ E L + I P +W G I D+ I +
Sbjct: 927 AAPVIK--RKIEP-LEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYI 983
Query: 336 SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVT 371
S L+I + D GEY +A N G + +TVT
Sbjct: 984 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVT 1019
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 162 GHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD 221
GH + S V PP F+K L+ + + F T G P+PT+ WFK+
Sbjct: 144 GHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKE 203
Query: 222 DYEIFSS-RRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
+ ++ +S T I + + + D G C A N G + A L
Sbjct: 204 NKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAEL 255
Score = 39.9 bits (89), Expect = 0.048
Identities = 34/124 (27%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 149 HKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTF 208
H+ ++ ALND G + S LTV A PV +++E + +F
Sbjct: 900 HQGEYVCEALNDSGKT---ATSAKLTVVKRAA----PVIKRKIEPLEVALGHLAKFTCEI 952
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
P+ WFK EI+ S + +I + + S L + D GE C A+N G
Sbjct: 953 QSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSC 1012
Query: 269 KARL 272
A L
Sbjct: 1013 TATL 1016
Score = 33.5 bits (73), Expect = 4.2
Identities = 21/91 (23%), Positives = 36/91 (39%)
Query: 300 LKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNII 359
L T++G P P I+W +G + + L I K D GEY A N
Sbjct: 68 LSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDY 127
Query: 360 GEDTAAFLVTVTAPPDPPRNVSVTRQVDKSV 390
G+ + + + + + ++ V KS+
Sbjct: 128 GKTICSAYLKINSKGEGHKDTETESAVAKSL 158
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 62.5 bits (145), Expect = 8e-09
Identities = 62/229 (27%), Positives = 91/229 (39%), Gaps = 20/229 (8%)
Query: 150 KYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFS 209
KYQ V N G SNYS+ + LTV+ E P F+K D+T
Sbjct: 585 KYQCIVT--NHFG-SNYSQKAK-LTVN------EMPSFLKTPMDLTIRTGAMARLECAAE 634
Query: 210 GIPSPTIAWFKD---DYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHA 266
G P+P I+W KD D+ RR + ++ V + D G C A N G
Sbjct: 635 GHPAPQISWQKDGGTDFPAARERRMHVMPED--DVFFIANVKIEDMGIYSCMAQNTAGGL 692
Query: 267 VTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDR 326
A L + P + R ED + ET L+ G P P + W D P++ +R
Sbjct: 693 SANASLTVLETPS--FIRPLEDKTVTR-GETAVLQCIAGGSPAPRLNWTKDDGPLLVTER 749
Query: 327 IEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPD 375
+ + +L I A D G+Y N +G + + V + P+
Sbjct: 750 HFFAAANQ--LLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNVISSPN 796
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/156 (29%), Positives = 67/156 (42%), Gaps = 14/156 (8%)
Query: 237 ESTSVLLFHQILPSDEGEIKCTATNR-GGHAVTKARLCLEAAPK-LRYPRQYEDGLLYEI 294
E TS+L + +DEG+ +C TN G + KA+L + P L+ P L
Sbjct: 568 EYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMD----LTIRT 623
Query: 295 NETIFLKTTIVGKPTPTIEWRHDG---HPIITDDRIEISITPKFSVLKIHSAKRSDRGEY 351
L+ G P P I W+ DG P + R+ + P+ V I + K D G Y
Sbjct: 624 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMH--VMPEDDVFFIANVKIEDMGIY 681
Query: 352 QIQAKNIIGEDTAAFLVTVTAPPD---PPRNVSVTR 384
A+N G +A +TV P P + +VTR
Sbjct: 682 SCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTR 717
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 62.1 bits (144), Expect = 1e-08
Identities = 49/177 (27%), Positives = 76/177 (42%), Gaps = 6/177 (3%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAA 277
W + E+ +S S L Q DEG + C + + G + K + L +
Sbjct: 879 WVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEG--IVKCQYDLTLS 936
Query: 278 PKLR-YPRQYEDGLLYEINE--TIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPK 334
+L P INE + I G+P+P IEW + PI + IS +
Sbjct: 937 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 996
Query: 335 FSVLKIHSAKRSDRGEYQIQAKNIIGEDTA-AFLVTVTAPPDPPRNVSVTRQVDKSV 390
L+I +A SD G+Y I+AKN G+ +A A L+ + +P R V + D S+
Sbjct: 997 VYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 1053
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEP----PVFIKRLEDVTALENDKVEFHVTFS 209
+V+ +++ S+ +T ++ + EP PV + L+D T + +F V +
Sbjct: 626 KVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKAT 685
Query: 210 GIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTK 269
G P PT W KD I + ++ D+ L H+ SD G CT N G +
Sbjct: 686 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 745
Query: 270 ARLCLEA 276
+L ++A
Sbjct: 746 CKLTIKA 752
Score = 48.4 bits (110), Expect = 1e-04
Identities = 21/65 (32%), Positives = 34/65 (52%)
Query: 306 GKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAA 365
G+P PT+ W G + T R +++ T S +I S + SD G Y + +N G+ A
Sbjct: 395 GEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAE 454
Query: 366 FLVTV 370
F +T+
Sbjct: 455 FTLTI 459
Score = 43.2 bits (97), Expect = 0.005
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 2/100 (2%)
Query: 173 LTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTA 232
LT+S + + + P FI + E V F SG PSP I WFK++ I S +
Sbjct: 933 LTLSKELS--DAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVS 990
Query: 233 ITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARL 272
I+ + L SD G+ A N G A L
Sbjct: 991 ISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASL 1030
Score = 41.5 bits (93), Expect = 0.016
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 7/127 (5%)
Query: 256 KCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIV-------GKP 308
K + T + T++ + + PK P + ++ + +T ++ G+P
Sbjct: 629 KISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEP 688
Query: 309 TPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
PT W DG I + ++S L+IH SD G Y KN G +++ +
Sbjct: 689 RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKL 748
Query: 369 TVTAPPD 375
T+ A D
Sbjct: 749 TIKAIKD 755
Score = 40.7 bits (91), Expect = 0.027
Identities = 21/84 (25%), Positives = 33/84 (39%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+T E + F G P PT+ W + + +S R +TT + S + SDEG
Sbjct: 379 MTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEG 438
Query: 254 EIKCTATNRGGHAVTKARLCLEAA 277
N G + L ++ A
Sbjct: 439 NYSVVVENSEGKQEAEFTLTIQKA 462
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 306 GKPTPTIEWRHDGHPIITDD--RIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G+PTP + W G I + + R I T + L I ++ D G Y + N G D+
Sbjct: 1163 GEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDS 1222
Query: 364 A 364
A
Sbjct: 1223 A 1223
Score = 33.1 bits (72), Expect = 5.5
Identities = 18/68 (26%), Positives = 29/68 (42%)
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
+ KPT ++W H+G + +I + T L+I D G Y+ N GE +
Sbjct: 206 VQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEAS 265
Query: 364 AAFLVTVT 371
+ VT
Sbjct: 266 DYATLDVT 273
>BC067101-1|AAH67101.1| 1212|Homo sapiens MYOM3 protein protein.
Length = 1212
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 326 RIEISITPKFSVLKI---HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
R+ S+ K S L + H A R + E N I T AF TVT P PP NV
Sbjct: 452 RVGSSVPSKASELVVMGDHDAARR-KTEIPFDLGNKITISTDAFEDTVTIP-SPPTNVHA 509
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTLFDLIE 438
+ + V L WE P+ G + Y +E G W +AI+S R + DL +
Sbjct: 510 SEIREAYVVLAWEEPSPRGRAPL-TYSLEKSVIGSGTW-EAISSESPVRSPRFAVLDLEK 567
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
Y FR++A + YG+S PS S P+ + G
Sbjct: 568 KKSYVFRVRAMNQYGLSDPSEPSEPIALRG 597
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 9/163 (5%)
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+I+W DG + + R +I T + + LK+ + D G Y ++ + G + V V
Sbjct: 303 SIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLV 362
Query: 371 T-------APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
P P NV + L W PP+D G + Y +E + W+
Sbjct: 363 RDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIAC 422
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG Y+FR++A S G S PS S V
Sbjct: 423 HEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELV 465
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 8/143 (5%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI--RTA 131
A P PG P + L D + + L WAP + G P+ Y +E + S EWI A
Sbjct: 367 AENPGAPGSPLNVRCL-DVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 425
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
P R + GL Y+FRV A++ VG S S+ S+++ + A++ L
Sbjct: 426 PGGTCR--CPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDL 483
Query: 192 EDVTALENDKVEFHVTFSGIPSP 214
+ + D E VT IPSP
Sbjct: 484 GNKITISTDAFEDTVT---IPSP 503
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + S+ ++ L+W P + G P+ GY V GS +W P +
Sbjct: 802 PGPPYDVRA-SEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTH 860
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE 183
L ++ L+P Y F+V A+N G S +D + + + E
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHE 904
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP +V + S+ L WEPP G V Y V + G W K +T T+
Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQW-KPVTPGPISGTH 860
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + DL G Y F+++A + G+ PS + PV
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPV 894
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVLRPELVLTGLEPPHKYQFR 154
+ L W + G APL Y +E + +GS W I + P V P + LE Y FR
Sbjct: 517 VVLAWEEPSPRGRAPLT-YSLEKSVIGSGTWEAISSESP-VRSPRFAVLDLEKKKSYVFR 574
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED 193
V A+N G S+ SE S+ + + A+ PP ++ D
Sbjct: 575 VRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 613
Score = 45.2 bits (102), Expect = 0.001
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 14/143 (9%)
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTAPP---DPPRNVSVTRQ 385
+P+F+VL + K ++++A N G + + + PP PP V R
Sbjct: 557 SPRFAVLDLEKKKSY---VFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 613
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYK 443
SV+L W+P D ++ Y + + G + W + T T+ L G EY+
Sbjct: 614 TQTSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYE 670
Query: 444 FRIKAESPYGMSAPSSESSPVRI 466
F +++ S G+ S+ + P+R+
Sbjct: 671 FCVRSVSEAGVGESSAATEPIRV 693
Score = 37.9 bits (84), Expect = 0.19
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 15/145 (10%)
Query: 359 IGEDTAAF----LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY- 413
+GE +AA + A P P ++ + + W+PP GG K+ Y ++ +
Sbjct: 681 VGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHD 740
Query: 414 --RTGWN-VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG---MSAPSS--ESSPVR 465
W+ V + I +R V+ DL EG Y+FR +A + G +SAPSS E
Sbjct: 741 SEELDWHAVNQQPIPTRVCKVS--DLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWT 798
Query: 466 IPGRAIDMDFLAVEARIINEALTRE 490
+P D A E R + L E
Sbjct: 799 MPQPGPPYDVRASEVRATSLVLQWE 823
Score = 36.7 bits (81), Expect = 0.45
Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 4/111 (3%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G PA P + D + +++L W P L GY + ++G++EW
Sbjct: 597 GPPATLPPPAQVQAFRDTQ-TSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKP 652
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ + GL +Y+F V ++++ G S ++ + V A+ P
Sbjct: 653 IQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAP 703
Score = 35.5 bits (78), Expect = 1.0
Identities = 27/119 (22%), Positives = 44/119 (36%), Gaps = 1/119 (0%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
A P P +L+ + N + + W P GG + GY ++ + +W +
Sbjct: 698 ATPSAPYGFALLNCGK-NEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPT 756
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ L H Y+FR A N G S S + Q P + R +V A
Sbjct: 757 RVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRA 815
>AK128233-1|BAC87343.1| 1172|Homo sapiens protein ( Homo sapiens
cDNA FLJ46367 fis, clone TESTI4051424, weakly similar
to M-protein, striated muscle. ).
Length = 1172
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 326 RIEISITPKFSVLKI---HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
R+ S+ K S L + H A R + E N I T AF TVT P PP NV
Sbjct: 187 RVGSSVPSKASELVVMGDHDAARR-KTEIPFDLGNKITISTDAFEDTVTIP-SPPTNVHA 244
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTLFDLIE 438
+ + V L WE P+ G + Y +E G W +AI+S R + DL +
Sbjct: 245 SEIREAYVVLAWEEPSPRGRAPL-TYSLEKSVIGSGTW-EAISSESPVRSPRFAVLDLEK 302
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
Y FR++A + YG+S PS S P+ + G
Sbjct: 303 KKSYVFRVRAMNQYGLSDPSEPSEPIALRG 332
Score = 57.2 bits (132), Expect = 3e-07
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 9/163 (5%)
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+I+W DG + + R +I T + + LK+ + D G Y ++ + G + V V
Sbjct: 38 SIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYTVRVPSPFGPREQSTYVLV 97
Query: 371 T-------APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
P P NV + L W PP+D G + Y +E + W+
Sbjct: 98 RDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIAC 157
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG Y+FR++A S G S PS S V
Sbjct: 158 HEAPGGTCRCPIRGLVEGQSYRFRVRAISRVGSSVPSKASELV 200
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 8/143 (5%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI--RTA 131
A P PG P + L D + + L WAP + G P+ Y +E + S EWI A
Sbjct: 102 AENPGAPGSPLNVRCL-DVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 160
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
P R + GL Y+FRV A++ VG S S+ S+++ + A++ L
Sbjct: 161 PGGTCR--CPIRGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDL 218
Query: 192 EDVTALENDKVEFHVTFSGIPSP 214
+ + D E VT IPSP
Sbjct: 219 GNKITISTDAFEDTVT---IPSP 238
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + S+ ++ L+W P + G P+ GY V GS +W P +
Sbjct: 537 PGPPYDVRA-SEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTH 595
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE 183
L ++ L+P Y F+V A+N G S +D + + + E
Sbjct: 596 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHE 639
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP +V + S+ L WEPP G V Y V + G W K +T T+
Sbjct: 537 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQW-KPVTPGPISGTH 595
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + DL G Y F+++A + G+ PS + PV
Sbjct: 596 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPV 629
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVLRPELVLTGLEPPHKYQFR 154
+ L W + G APL Y +E + +GS W I + P V P + LE Y FR
Sbjct: 252 VVLAWEEPSPRGRAPLT-YSLEKSVIGSGTWEAISSESP-VRSPRFAVLDLEKKKSYVFR 309
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED 193
V A+N G S+ SE S+ + + A+ PP ++ D
Sbjct: 310 VRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 348
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/86 (25%), Positives = 37/86 (43%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
++T+ L + G PTP I W + P+ DR + + + I D G Y +
Sbjct: 1084 DKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVF 1143
Query: 355 AKNIIGEDTAAFLVTVTAPPDPPRNV 380
KN G +T ++V D P+ +
Sbjct: 1144 VKNKYGSETGQVTISVFKHGDEPKEL 1169
Score = 44.8 bits (101), Expect = 0.002
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 14/143 (9%)
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTAPP---DPPRNVSVTRQ 385
+P+F+VL + K ++++A N G + + + PP PP V R
Sbjct: 292 SPRFAVLDLEKKKSY---VFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 348
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYK 443
SV+L W+P D ++ Y + + G + W + T T+ L G EY+
Sbjct: 349 TQTSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPRLRTGKEYE 405
Query: 444 FRIKAESPYGMSAPSSESSPVRI 466
F +++ S G+ S+ + P+R+
Sbjct: 406 FCVRSVSEAGVGESSAATEPIRV 428
Score = 38.3 bits (85), Expect = 0.15
Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 24/174 (13%)
Query: 334 KFSVLKIHSAKRSDRGEYQIQAKNI----IGEDTAAF----LVTVTAPPDPPRNVSVTRQ 385
+F+V ++ + K EY+ +++ +GE +AA + A P P ++
Sbjct: 392 RFTVPRLRTGK-----EYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNC 446
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYY---RTGWN-VWLKAITSRKTNVTLFDLIEGSE 441
+ + W+PP GG K+ Y ++ + W+ V + I +R V+ DL EG
Sbjct: 447 GKNEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVS--DLHEGHF 504
Query: 442 YKFRIKAESPYG---MSAPSS--ESSPVRIPGRAIDMDFLAVEARIINEALTRE 490
Y+FR +A + G +SAPSS E +P D A E R + L E
Sbjct: 505 YEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWE 558
Score = 35.5 bits (78), Expect = 1.0
Identities = 27/119 (22%), Positives = 44/119 (36%), Gaps = 1/119 (0%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
A P P +L+ + N + + W P GG + GY ++ + +W +
Sbjct: 433 ATPSAPYGFALLNCGK-NEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPT 491
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ L H Y+FR A N G S S + Q P + R +V A
Sbjct: 492 RVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRA 550
>AK125972-1|BAC86370.1| 365|Homo sapiens protein ( Homo sapiens
cDNA FLJ43984 fis, clone TESTI4018886, weakly similar
to M-protein, striated muscle. ).
Length = 365
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 11/150 (7%)
Query: 326 RIEISITPKFSVLKI---HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
R+ S+ K S L + H A R + E N I T AF TVT P PP NV
Sbjct: 109 RVGSSVPSKASELVVMGDHDAARR-KTEIPFDLGNKITISTDAFEDTVTIP-SPPTNVHA 166
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTLFDLIE 438
+ + V L WE P+ G + Y +E G W +AI+S R + DL +
Sbjct: 167 SEIREAYVVLAWEEPSPRGRAPL-TYSLEKSVIGSGTW-EAISSESPVRSPRFAVLDLEK 224
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
Y FR++A + YG+S PS S P+ + G
Sbjct: 225 KKSYVFRVRAMNQYGLSDPSEPSEPIALRG 254
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 8/143 (5%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI--RTA 131
A P PG P + L D + + L WAP + G P+ Y +E + S EWI A
Sbjct: 24 AENPGAPGSPLNVRCL-DVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 82
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
P R + GL Y+FRV A++ VG S S+ S+++ + A++ L
Sbjct: 83 PGGTCR--CPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDL 140
Query: 192 EDVTALENDKVEFHVTFSGIPSP 214
+ + D E VT IPSP
Sbjct: 141 GNKITISTDAFEDTVT---IPSP 160
Score = 48.4 bits (110), Expect = 1e-04
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVLRPELVLTGLEPPHKYQFR 154
+ L W + G APL Y +E + +GS W I + P V P + LE Y FR
Sbjct: 174 VVLAWEEPSPRGRAPLT-YSLEKSVIGSGTWEAISSESP-VRSPRFAVLDLEKKKSYVFR 231
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED 193
V A+N G S+ SE S+ + + A+ PP ++ D
Sbjct: 232 VRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 270
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA--ITSRKTNV 431
P P NV + L W PP+D G + Y +E + W+
Sbjct: 30 PGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEAPGGTCRC 89
Query: 432 TLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG Y+FR++A S G S PS S V
Sbjct: 90 PIQGLVEGQSYRFRVRAISRVGSSVPSKASELV 122
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 61.3 bits (142), Expect = 2e-08
Identities = 69/282 (24%), Positives = 112/282 (39%), Gaps = 18/282 (6%)
Query: 186 VFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFH 245
V + E+ T + V S P+P ++W + D + S T + T++L+ +
Sbjct: 245 VIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPIS---TDVIVLGRTNLLIAN 301
Query: 246 QILPSDEGEIKCTATN--RGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
P G C A A A L + AAP + Q + L T
Sbjct: 302 A-QPWHSGVYVCRANKPRTRDFATAAAELRVLAAPAIT---QAPEALSRTRASTARFVCR 357
Query: 304 IVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDT 363
G+P P + W H+G P+ + R+++ L I D G YQ A+N G
Sbjct: 358 ASGEPRPALRWLHNGAPLRPNGRVKVQ--GGGGSLVITQIGLQDAGYYQCVAENSAGMAC 415
Query: 364 AAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGW--N 418
AA + V P P V+ T +V + WE P +G + + Y + N
Sbjct: 416 AAASLAVVVREGLPSAPTRVTATPLSSSAVLVAWERPEMHSEQIIG-FSLHYQKARGMDN 474
Query: 419 V-WLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
V + A+ + T + + DL ++Y+F + A S G S S+
Sbjct: 475 VEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTST 516
Score = 49.6 bits (113), Expect = 6e-05
Identities = 38/142 (26%), Positives = 55/142 (38%), Gaps = 12/142 (8%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSD 251
E T EN F G+P+P I W KD + R + + VL + SD
Sbjct: 150 ESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPN---GVLQILDVQESD 206
Query: 252 EGEIKCTATNRG-GHAVTKARLCLEAAPKLRYPRQYE-------DGLLYEINETIFLKTT 303
G +C ATN H +A L + L R + + +++ ++
Sbjct: 207 AGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECV 266
Query: 304 IVGKPTPTIEW-RHDGHPIITD 324
PTP + W R DG PI TD
Sbjct: 267 ASADPTPFVSWVRQDGKPISTD 288
Score = 35.1 bits (77), Expect = 1.4
Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 5/102 (4%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE--W-IRTAPP 133
P P P LS P+ + L W P T G + + + E W + T
Sbjct: 844 PDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSSNHTQPEHQWTLLTTQG 903
Query: 134 IVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTV 175
+ E+ GLE +Y F++ A +VG +S L DV+T+
Sbjct: 904 NIFSAEV--HGLESDTRYFFKMGARTEVGPGPFSRLQDVITL 943
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 60.9 bits (141), Expect = 2e-08
Identities = 66/288 (22%), Positives = 109/288 (37%), Gaps = 17/288 (5%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ A + +V P P +W K + +S R I D S + + I +D G
Sbjct: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEI---NNITRNDGG 480
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G A + L + ++ D + E N T+ + T
Sbjct: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGE-NATMQCAASFDPALDLTFV 539
Query: 314 WRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
W +G+ +I ++ I F + L I +A+ G Y A+ I+ +A+ +
Sbjct: 540 WSFNGY-VIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 598
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA----- 423
V PP PP + + SV L W +D+ + Y ++ + W A
Sbjct: 599 VVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHS-PISKYTIQTKTILSDDWKDAKTDPP 657
Query: 424 -ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRA 470
I DLI EY+FR+ A + G PS S+ ++ G A
Sbjct: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAA 705
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 7/156 (4%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ ++ + P + + +DV AL V G P P I W K
Sbjct: 221 SVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--- 277
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ + S +VL I DEG +C A N G +AR+ ++A P+ +
Sbjct: 278 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPE--WV 334
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
D + +I ++ GKP PTI W +G+
Sbjct: 335 EHINDTEV-DIGSDLYWPCVATGKPIPTIRWLKNGY 369
Score = 45.6 bits (103), Expect = 0.001
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG-GHAVTKARLCLEA 276
W +++ +F + ++ L + SD+G C ++ +V + L
Sbjct: 172 WLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIP 231
Query: 277 APKLR---YPR----QYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
P+ YP Q++D +Y + + + L+ +G P P I WR P+ + I
Sbjct: 232 IPERTTKPYPADIVVQFKD--VYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIS 289
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
S +VLKI + + D G Y+ +A+NI G+D + V A P+ +++ T +VD
Sbjct: 290 TS----GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDT-EVDI 344
Query: 389 SVTLDW 394
L W
Sbjct: 345 GSDLYW 350
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 60.9 bits (141), Expect = 2e-08
Identities = 66/288 (22%), Positives = 109/288 (37%), Gaps = 17/288 (5%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ A + +V P P +W K + +S R I D S + + I +D G
Sbjct: 413 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEI---NNITRNDGG 469
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G A + L + ++ D + E N T+ + T
Sbjct: 470 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGE-NATMQCAASFDPALDLTFV 528
Query: 314 WRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
W +G+ +I ++ I F + L I +A+ G Y A+ I+ +A+ +
Sbjct: 529 WSFNGY-VIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 587
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA----- 423
V PP PP + + SV L W +D+ + Y ++ + W A
Sbjct: 588 VVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHS-PISKYTIQTKTILSDDWKDAKTDPP 646
Query: 424 -ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRA 470
I DLI EY+FR+ A + G PS S+ ++ G A
Sbjct: 647 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAA 694
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 7/156 (4%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ ++ + P + + +DV AL V G P P I W K
Sbjct: 210 SVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--- 266
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ + S +VL I DEG +C A N G +AR+ ++A P+ +
Sbjct: 267 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPE--WV 323
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
D + +I ++ GKP PTI W +G+
Sbjct: 324 EHINDTEV-DIGSDLYWPCVATGKPIPTIRWLKNGY 358
Score = 45.6 bits (103), Expect = 0.001
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG-GHAVTKARLCLEA 276
W +++ +F + ++ L + SD+G C ++ +V + L
Sbjct: 161 WLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIP 220
Query: 277 APKLR---YPR----QYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
P+ YP Q++D +Y + + + L+ +G P P I WR P+ + I
Sbjct: 221 IPERTTKPYPADIVVQFKD--VYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIS 278
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
S +VLKI + + D G Y+ +A+NI G+D + V A P+ +++ T +VD
Sbjct: 279 TS----GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDT-EVDI 333
Query: 389 SVTLDW 394
L W
Sbjct: 334 GSDLYW 339
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 60.9 bits (141), Expect = 2e-08
Identities = 66/288 (22%), Positives = 109/288 (37%), Gaps = 17/288 (5%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+ A + +V P P +W K + +S R I D S + + I +D G
Sbjct: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEI---NNITRNDGG 480
Query: 254 EIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIE 313
C A N G A + L + ++ D + E N T+ + T
Sbjct: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGE-NATMQCAASFDPALDLTFV 539
Query: 314 WRHDGHPIITDDRIEISITPKFSV-----LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLV 368
W +G+ +I ++ I F + L I +A+ G Y A+ I+ +A+ +
Sbjct: 540 WSFNGY-VIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 598
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA----- 423
V PP PP + + SV L W +D+ + Y ++ + W A
Sbjct: 599 VVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHS-PISKYTIQTKTILSDDWKDAKTDPP 657
Query: 424 -ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRA 470
I DLI EY+FR+ A + G PS S+ ++ G A
Sbjct: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAA 705
Score = 50.8 bits (116), Expect = 3e-05
Identities = 39/156 (25%), Positives = 63/156 (40%), Gaps = 7/156 (4%)
Query: 164 SNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDY 223
S +S+ ++ + P + + +DV AL V G P P I W K
Sbjct: 221 SVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--- 277
Query: 224 EIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYP 283
+ + S +VL I DEG +C A N G +AR+ ++A P+ +
Sbjct: 278 -VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPE--WV 334
Query: 284 RQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
D + +I ++ GKP PTI W +G+
Sbjct: 335 EHINDTEV-DIGSDLYWPCVATGKPIPTIRWLKNGY 369
Score = 45.6 bits (103), Expect = 0.001
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 218 WFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG-GHAVTKARLCLEA 276
W +++ +F + ++ L + SD+G C ++ +V + L
Sbjct: 172 WLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIP 231
Query: 277 APKLR---YPR----QYEDGLLYEI-NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
P+ YP Q++D +Y + + + L+ +G P P I WR P+ + I
Sbjct: 232 IPERTTKPYPADIVVQFKD--VYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIS 289
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSVTRQVDK 388
S +VLKI + + D G Y+ +A+NI G+D + V A P+ +++ T +VD
Sbjct: 290 TS----GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDT-EVDI 344
Query: 389 SVTLDW 394
L W
Sbjct: 345 GSDLYW 350
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 60.5 bits (140), Expect = 3e-08
Identities = 77/320 (24%), Positives = 117/320 (36%), Gaps = 40/320 (12%)
Query: 183 EPPVFIKRLEDV-TALENDKVEFHVTFSGIPSPTIAWFK--------DDYEIFSSRRTAI 233
EPP + + + N F G P PTI WFK +D + T
Sbjct: 447 EPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLE 506
Query: 234 TTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYE 293
D + V G C A N+ G A + L E A R G +
Sbjct: 507 IKDATWIVKEIPVAQKDSTGTYTCVARNKLGMAKNEVHLQPEYAVVQR-------GSMVS 559
Query: 294 INETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQI 353
+ T+ + T+ W D + +D+R + L + D G Y
Sbjct: 560 FECKVKHDHTL----SLTVLWLKDNRELPSDERFTVDKDH----LVVADVSDDDSGTYTC 611
Query: 354 QAKNIIGEDTAAFLVTVTAP----------PDPPRNVSVTRQVDKSVTLDWEPPADDGGC 403
A + +A+ +++V AP P+PP ++ +T Q+DKSV L W P DD
Sbjct: 612 VANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSW-TPGDDNNS 670
Query: 404 KVGNYIVEY----YRTGWNVWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
+ +I+EY ++ G ++ +T L L Y FR+ A + G S PS
Sbjct: 671 PITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQL-KLSPYVNYSFRVMAVNSIGKSLPSE 729
Query: 460 ESSPVRIPGRAIDMDFLAVE 479
S D + AVE
Sbjct: 730 ASEQYLTKASEPDKNPTAVE 749
Score = 51.2 bits (117), Expect = 2e-05
Identities = 57/229 (24%), Positives = 92/229 (40%), Gaps = 14/229 (6%)
Query: 154 RVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK---RLEDVTALENDKVEFHVTFSG 210
+V +++++ + + LSD + + + PP F+ + L + + G
Sbjct: 232 KVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEG 291
Query: 211 IPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
+P+P I W K+D + RT E T ++ + +D G +C A N G
Sbjct: 292 LPTPIIYWAKED-GMLPKNRTVYKNFEKTLQII--HVSEADSGNYQCIAKNALGAIHHTI 348
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPI-ITDDRIEI 329
+ ++AAP Y L+ E L G P P I W +G PI I D
Sbjct: 349 SVRVKAAP---YWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSR 405
Query: 330 SITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
I +++ + +RS YQ A N G A V V A +PPR
Sbjct: 406 KIDGD-TIIFSNVQERSS-AVYQCNASNEYGYLLANAFVNVLA--EPPR 450
Score = 37.5 bits (83), Expect = 0.26
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 8/95 (8%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY------YRTGWNVWLKAITSR 427
P P ++ + S+TL+W+PP+ G + Y ++Y + G V LK I +
Sbjct: 947 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGI-LTEYTLKYQPINSTHELGPLVDLK-IPAN 1004
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESS 462
KT TL +L + YKF A++ G + +E +
Sbjct: 1005 KTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEA 1039
Score = 36.7 bits (81), Expect = 0.45
Identities = 39/165 (23%), Positives = 66/165 (40%), Gaps = 20/165 (12%)
Query: 209 SGIPSPTIAWFKDDYEI-FSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAV 267
+G P P I+W + I + + D T ++F + +C A+N G+ +
Sbjct: 380 NGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT--IIFSNVQERSSAVYQCNASNEYGYLL 437
Query: 268 TKARL-CLEAAPKLRYPRQYEDGLLYEI--NETIFLKTTIVGKPTPTIEW---------R 315
A + L P++ P LY++ N L G P PTIEW
Sbjct: 438 ANAFVNVLAEPPRILTPAN----TLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 493
Query: 316 HDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
D + + + +EI + V +I A++ G Y A+N +G
Sbjct: 494 EDIYVLHENGTLEIK-DATWIVKEIPVAQKDSTGTYTCVARNKLG 537
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 60.5 bits (140), Expect = 3e-08
Identities = 77/307 (25%), Positives = 117/307 (38%), Gaps = 20/307 (6%)
Query: 161 VGHSNYS-ELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWF 219
V H S E S + + + S P I +++T + V +G P P I+W
Sbjct: 210 VAHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWS 269
Query: 220 KDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRG--GHAVTKARLCLEAA 277
+ D++ T + + + L+ + G C AT G V A L + A
Sbjct: 270 RLDHKSIDVFNTRVLGNGN---LMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAP 326
Query: 278 PKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSV 337
P ++ + L T G P+P + W +G I ++ RI++ S
Sbjct: 327 PSF---VEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKM----YNSK 379
Query: 338 LKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAP---PDPPRNVSVTRQVDKSVTLDW 394
L I+ D YQ A+N G + +TV P P NV ++ L W
Sbjct: 380 LVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRPSAPYNVHAETMSSSAILLAW 439
Query: 395 EPPADDGGCKVGNYIVEYYRT-GWN--VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESP 451
E P + KV Y V Y + G N + I + T+ + DL S Y F I A P
Sbjct: 440 ERPLYNSD-KVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVAYMP 498
Query: 452 YGMSAPS 458
G S S
Sbjct: 499 MGASQMS 505
Score = 38.3 bits (85), Expect = 0.15
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 10/176 (5%)
Query: 187 FIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDES--TSVLLF 244
F+K +DVT D V G + W K+ ++ ++R + ++ S S +
Sbjct: 41 FVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVEG 100
Query: 245 HQILPSDEGEIKCTATNRGGHAVT-KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTT 303
+ SDEG +C A N+ G ++ KA L L + Q ++E F
Sbjct: 101 RRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTIS--AFEVQPISTEVHEGGVARF-ACK 157
Query: 304 IVGKPTPTIEWRHDGHPI-ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNI 358
I P I W + + +T DRI T VL+I+ + D G Y+ A +
Sbjct: 158 ISSHPPAVITWEFNRTTLPMTMDRITALPT---GVLQIYDVSQRDSGNYRCIAATV 210
Score = 36.3 bits (80), Expect = 0.59
Identities = 52/211 (24%), Positives = 84/211 (39%), Gaps = 17/211 (8%)
Query: 76 RPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIV 135
R PP P + ++I L W A + Y + CN +G
Sbjct: 717 RMVPPPPPPHHLYAKANTSSSIFLHWRRPAFTA-AQIINYTIRCNPVGLQNASLVLYLQT 775
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIK--RLED 193
+++ GLEP KY+F V D S +S + V + A PPV +K +ED
Sbjct: 776 SETHMLVQGLEPNTKYEFAVRLHVDQLSSPWSPV--VYHSTLPEAPAGPPVGVKVTLIED 833
Query: 194 VTALEN----DKVEFHVT-FSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQIL 248
TAL + D E VT ++ + + AW ++++ R AIT + L ++
Sbjct: 834 DTALVSWKPPDGPETVVTRYTILYASRKAWIAGEWQVL-HREGAIT------MALLENLV 886
Query: 249 PSDEGEIKCTATNRGGHAVTKARLCLEAAPK 279
+ +K +A+N G + L PK
Sbjct: 887 AGNVYIVKISASNEVGEGPFSNSVELAVLPK 917
Score = 35.9 bits (79), Expect = 0.78
Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY-YRTGWNVWLKAITSRKTN 430
AP PP V VT D + + W+PP D V Y + Y R W + R+
Sbjct: 818 APAGPPVGVKVTLIEDDTALVSWKPP-DGPETVVTRYTILYASRKAWIAGEWQVLHREGA 876
Query: 431 VT---LFDLIEGSEYKFRIKAESPYGMSAPSSES 461
+T L +L+ G+ Y +I A + G P S S
Sbjct: 877 ITMALLENLVAGNVYIVKISASNEVG-EGPFSNS 909
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/193 (26%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 209 SGIPSPTIAWFKDDYEIF--------SSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
SG P P I+W D + S RT T + L F+++ ++EG+ C A
Sbjct: 42 SGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQ 101
Query: 261 NRGGHAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G K L + AAP++R + + + +T L + G P P I W +
Sbjct: 102 NTLGKDEMKVHLTVITAAPRIRQSNKTNKRI--KAGDTAVLDCEVTGDPKPKIFWLLPSN 159
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
+I+ + S L I+ K D GEY A+N G+DT + + V + P
Sbjct: 160 DMISFSIDRYTFHANGS-LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLING 218
Query: 380 VSVTRQVDKSVTL 392
+ +R V K+ +
Sbjct: 219 LYTSRTVIKATAV 231
Score = 58.0 bits (134), Expect = 2e-07
Identities = 53/224 (23%), Positives = 83/224 (37%), Gaps = 14/224 (6%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++R AA N VG Y E +L + Q+P + V + + + H GI
Sbjct: 387 KYRCAARNKVG---YIEKLVILEIG-----QKPVILTYAPGTVKGISGESLSLHCVSDGI 438
Query: 212 PSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W Y + + L+ + D G C A N GH +
Sbjct: 439 PKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 498
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
+ + A P R + ++ L +G P P I W H +++ E +
Sbjct: 499 PVMIVAYPP-RITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERT 557
Query: 331 ITPKF----SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ L I + + SD G Y+ AKN +G D AA + V
Sbjct: 558 HGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 601
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 3/169 (1%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
TA+ + K F G PSP + W D+ + + + T L + SD
Sbjct: 229 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 288
Query: 254 EIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ C A N GG +V +L LE + + + + ++ ++ ++ L ++ G P P I
Sbjct: 289 DFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEI 348
Query: 313 EW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
W +G + + I R D G+Y+ A+N +G
Sbjct: 349 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 397
Score = 45.6 bits (103), Expect = 0.001
Identities = 52/203 (25%), Positives = 81/203 (39%), Gaps = 16/203 (7%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFHQILPS 250
E + A + + G P P I W + FS+ + S + +
Sbjct: 324 EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 383
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPT 309
D G+ +C A N+ G+ L + P + Y G + I+ E++ L G P
Sbjct: 384 DAGKYRCAARNKVGYIEKLVILEIGQKPVIL---TYAPGTVKGISGESLSLHCVSDGIPK 440
Query: 310 PTIEWRHDGHPIITDDRIEIS---ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P I+W ++ DR +I+ I L I A DRG Y +A+N +G
Sbjct: 441 PNIKWTMPSGYVV--DRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 498
Query: 367 LVTVTA-PP----DPPRNVSVTR 384
V + A PP PPR++ VTR
Sbjct: 499 PVMIVAYPPRITNRPPRSI-VTR 520
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 353 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 412
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 413 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 444
>X69090-1|CAA48833.1| 1451|Homo sapiens 190kD protein protein.
Length = 1451
Score = 58.8 bits (136), Expect = 1e-07
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP ++SVT V L W+PP G + Y VE G W + T +
Sbjct: 501 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPR 559
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDM 473
LFDL EG Y FR++ + G+ P SE++ V + G +D+
Sbjct: 560 FALFDLAEGKSYCFRVRCSNSAGVGEP-SEATEVTVVGDKLDI 601
Score = 53.2 bits (122), Expect = 5e-06
Identities = 48/192 (25%), Positives = 79/192 (41%), Gaps = 13/192 (6%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVEC-NRLGSTEWIRTAPPIVL 136
A PG P + S+ +++ L+W P H G P+ GY V+ + +W +
Sbjct: 804 AVPGPPHSLKC-SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGLNEAAIK 862
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
L + GL+ Y FRV A+N G S+L+ + V+ R ++ V + V +
Sbjct: 863 NVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV-VAETRPGRKEVVVNVDDDGVIS 921
Query: 197 L--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGE 254
L E DK+ P +W KD S R + + + + + F + D G
Sbjct: 922 LNFECDKM--------TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGI 973
Query: 255 IKCTATNRGGHA 266
C T+ G A
Sbjct: 974 YSCDVTDTDGIA 985
Score = 52.4 bits (120), Expect = 8e-06
Identities = 37/164 (22%), Positives = 67/164 (40%), Gaps = 9/164 (5%)
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK-NIIGEDTAAFLV 368
P I W +G P+ ++ + + + L + D G Y I+ + E +A++
Sbjct: 303 PEIRWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 362
Query: 369 T------VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P +V + + W+ PA DGG + Y ++ G + W +
Sbjct: 363 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 422
Query: 423 AITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + + LIEG Y FR++A + G+ PS S V
Sbjct: 423 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEAV 466
Score = 49.2 bits (112), Expect = 8e-05
Identities = 38/116 (32%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PGK IIP + D ++ + W + L GY +E N GS +W V
Sbjct: 602 PKAPGK--IIPSRNTD--TSVVVSWEESKD--AKELVGYYIEANVAGSGKWEPCNNNPVK 655
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 192
GL Y FRV A+N G S YS+ S+ + V + A PP I LE
Sbjct: 656 THRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLE 711
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 11/122 (9%)
Query: 351 YQIQAKNIIG-----EDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
++++A N G +D+ A V APP PP +++ S+ L W+ P GG +
Sbjct: 672 FRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAE 731
Query: 405 VGNYIVEYYRTGWNV---WLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSS 459
+ Y V Y V W +A R+ + +L E Y+F++ A + G+ APS+
Sbjct: 732 ITGYYVNYREVIDGVPGKWREANVKAVREEAYKISNLKENMVYQFQVAAMNMAGLGAPSA 791
Query: 460 ES 461
S
Sbjct: 792 VS 793
Score = 46.0 bits (104), Expect = 7e-04
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
Query: 52 MGNHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
MG +Y ++A+ ++ + G PA P + + D I + W DGG+P
Sbjct: 350 MGEYYE-QYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD----YIIISWKQPAVDGGSP 404
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GY ++ +G+ W + V +TGL Y FRV A+N +G S +S+
Sbjct: 405 ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 464
Query: 172 VL 173
+
Sbjct: 465 AV 466
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/96 (28%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY-YRTGWNVW--LKAITSRK 428
A P PP ++ + S+ L W+PP G V Y V+ + + W L +
Sbjct: 804 AVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEKAKEDQWRGLNEAAIKN 863
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + L EG Y FR++A + G+ PS + PV
Sbjct: 864 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 899
Score = 41.9 bits (94), Expect = 0.012
Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 359 IGEDTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
+GE + A VTV P P + +R D SV + WE D ++ Y +E
Sbjct: 583 VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEANV 640
Query: 415 TGWNVWLKAITSR-KTN-VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
G W + KT+ T L+ G Y FR++A + G+S S +S + +
Sbjct: 641 AGSGKWEPCNNNPVKTHRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEV 694
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 1/92 (1%)
Query: 288 DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRS 346
D + + + + L + G P P + W + + D + + + I+ +
Sbjct: 1346 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALAQTDHCNLKFEAGRTAYFTINGVSTA 1405
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
D G+Y + KN G +T+ F V+V P + R
Sbjct: 1406 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEAR 1437
Score = 34.7 bits (76), Expect = 1.8
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 4/97 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRL--GSTEWIRTAPPIV 135
APP P I L +++ L W GGA + GY V + G R A
Sbjct: 699 APPSPPCDITCLESFR-DSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKA 757
Query: 136 LRPELV-LTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+R E ++ L+ YQF+VAA+N G S +S+
Sbjct: 758 VREEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 794
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
P FI + T E + V+ H + +G P P + W+K+ I
Sbjct: 141 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPI 181
>BC116183-1|AAI16184.1| 1589|Homo sapiens myomesin 1, 185kDa
protein.
Length = 1589
Score = 58.8 bits (136), Expect = 1e-07
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP ++SVT V L W+PP G + Y VE G W + T +
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDM 473
LFDL EG Y FR++ + G+ P SE++ V + G +D+
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEP-SEATEVTVVGDKLDI 738
Score = 54.0 bits (124), Expect = 3e-06
Identities = 37/164 (22%), Positives = 68/164 (41%), Gaps = 9/164 (5%)
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK-NIIGEDTAAFLV 368
P I+W +G P+ ++ + + + L + D G Y I+ + E +A++
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 369 T------VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P +V + + W+ PA DGG + Y ++ G + W +
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 423 AITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + + LIEG Y FR++A + G+ PS PV
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVFEPV 602
Score = 54.0 bits (124), Expect = 3e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 14/193 (7%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE--WIRTAPPIV 135
A PG P + S+ +++ L+W P H G P+ GY V+ + E W +
Sbjct: 941 AVPGPPHSLKC-SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 999
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L + GL+ Y FRV A+N G S+L+ + + ++E V + + V
Sbjct: 1000 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDD-DGVI 1058
Query: 196 AL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+L E DK+ P +W KD S R + + + + + F + D G
Sbjct: 1059 SLNFECDKM--------TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1110
Query: 254 EIKCTATNRGGHA 266
C T+ G A
Sbjct: 1111 IYSCDVTDTDGIA 1123
Score = 47.2 bits (107), Expect = 3e-04
Identities = 37/116 (31%), Positives = 50/116 (43%), Gaps = 6/116 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PGK IIP + D ++ + W + L GY +E + GS +W V
Sbjct: 739 PKAPGK--IIPSRNTD--TSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVK 792
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLE 192
GL Y FRV A+N G S YS+ S+ + V + A PP I LE
Sbjct: 793 GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLE 848
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 15/124 (12%)
Query: 351 YQIQAKNIIG-----EDTAAFLVTVT-APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCK 404
++++A N G +D+ A V APP PP +++ S+ L W+ P GG +
Sbjct: 809 FRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAE 868
Query: 405 VGNYIVEYYRTGWNV---W----LKAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAP 457
+ Y V Y V W +KA++ ++ +L E Y+F++ A + G+ AP
Sbjct: 869 ITGYYVNYREVIDGVPGKWREANVKAVSEEAYKIS--NLKENMVYQFQVAAMNMAGLGAP 926
Query: 458 SSES 461
S+ S
Sbjct: 927 SAVS 930
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/111 (27%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 52 MGNHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
MG +Y ++A+ ++ + G PA P + + D I + W DGG+P
Sbjct: 486 MGEYYE-QYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD----YIIISWKQPAVDGGSP 540
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVG 162
+ GY ++ +G+ W + V +TGL Y FRV A+N +G
Sbjct: 541 ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMG 591
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
+WR ++++ +IS + V + A + G + A + + E T+ A
Sbjct: 886 KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG---LGAPSAVSECFKCEEWTI-A 941
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAITSRK 428
P PP ++ + S+ L W+PP G V Y V+ + + W L +
Sbjct: 942 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1001
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + L EG Y FR++A + G+ PS + PV
Sbjct: 1002 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 1037
Score = 42.3 bits (95), Expect = 0.009
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Query: 359 IGEDTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
+GE + A VTV P P + +R D SV + WE D ++ Y +E
Sbjct: 720 VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASV 777
Query: 415 TGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
G W + + + T L+ G Y FR++A + G+S S +S + +
Sbjct: 778 AGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEV 831
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 288 DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRS 346
D + + + + L + G P P + W + + +DD + + + I+ +
Sbjct: 1484 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1543
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
D G+Y + KN G +T+ F V+V P + R
Sbjct: 1544 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEAR 1575
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
P FI + T E + V+ H + +G P P + W+K+ I
Sbjct: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPI 317
Score = 33.5 bits (73), Expect = 4.2
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST---EWIRTAPPI 134
APP P I L +++ L W GGA + GY V + +W
Sbjct: 836 APPSPPCDITCLESFR-DSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 894
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
V ++ L+ YQF+VAA+N G S +S+
Sbjct: 895 VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 931
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 61 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 120
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 121 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 152
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 62 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 121
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 122 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 153
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 122 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 181
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 182 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 213
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 121 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 180
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 181 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 212
>AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.
Length = 1115
Score = 58.8 bits (136), Expect = 1e-07
Identities = 54/230 (23%), Positives = 88/230 (38%), Gaps = 15/230 (6%)
Query: 153 FRVAALNDVGHS-NYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ AA N V S SD L V A ++ + + + + SGI
Sbjct: 198 YKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGI 257
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN---RGGHAVT 268
P P + W KD + +T S LL D G +C A N + G AV
Sbjct: 258 PPPRVTWAKDGSSVTGYNKTRFL----LSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVI 313
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + P++ L+ ++ L + G P P++ W + P+I+ R+
Sbjct: 314 LYNVQVFEPPEVTMELSQ---LVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLR 370
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
+S L++ S D G YQ A+N +G A + + P PR
Sbjct: 371 LS----RRALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPR 416
Score = 52.8 bits (121), Expect = 6e-06
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST-EWIRTAPP 133
GR +PP P P +S ++ + W P + GG P++ ++VE +L +WI
Sbjct: 602 GRLSPPEAPDR-PTISTASETSVYVTWIPRGN-GGFPIQSFRVEYKKLKKVGDWILATSA 659
Query: 134 IV-LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVS--SDRASQEP 184
I R + +TGLE Y+FRV ALN +G S S S VS S R + P
Sbjct: 660 IPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERP 713
Score = 52.4 bits (120), Expect = 8e-06
Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT----GWNVWLKAITSR 427
+PP+ P +++ + SV + W P + GG + ++ VEY + W + AI
Sbjct: 605 SPPEAPDRPTISTASETSVYVTWIPRGN-GGFPIQSFRVEYKKLKKVGDWILATSAIPPS 663
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
+ +V + L +G+ YKFR++A + G S PS+ S P + G
Sbjct: 664 RLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSG 704
>AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.
Length = 1114
Score = 58.8 bits (136), Expect = 1e-07
Identities = 54/230 (23%), Positives = 88/230 (38%), Gaps = 15/230 (6%)
Query: 153 FRVAALNDVGHS-NYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++ AA N V S SD L V A ++ + + + + SGI
Sbjct: 198 YKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGI 257
Query: 212 PSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATN---RGGHAVT 268
P P + W KD + +T S LL D G +C A N + G AV
Sbjct: 258 PPPRVTWAKDGSSVTGYNKTRFL----LSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVI 313
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIE 328
+ + P++ L+ ++ L + G P P++ W + P+I+ R+
Sbjct: 314 LYNVQVFEPPEVTMELSQ---LVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLR 370
Query: 329 ISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
+S L++ S D G YQ A+N +G A + + P PR
Sbjct: 371 LS----RRALRVLSMGPEDEGVYQCMAENEVGSAHAVVQLRTSRPSITPR 416
Score = 52.8 bits (121), Expect = 6e-06
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 6/114 (5%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST-EWIRTAPP 133
GR +PP P P +S ++ + W P + GG P++ ++VE +L +WI
Sbjct: 601 GRLSPPEAPDR-PTISTASETSVYVTWIPRGN-GGFPIQSFRVEYKKLKKVGDWILATSA 658
Query: 134 IV-LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVS--SDRASQEP 184
I R + +TGLE Y+FRV ALN +G S S S VS S R + P
Sbjct: 659 IPPSRLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSGYSGRVYERP 712
Score = 52.4 bits (120), Expect = 8e-06
Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
Query: 372 APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRT----GWNVWLKAITSR 427
+PP+ P +++ + SV + W P + GG + ++ VEY + W + AI
Sbjct: 604 SPPEAPDRPTISTASETSVYVTWIPRGN-GGFPIQSFRVEYKKLKKVGDWILATSAIPPS 662
Query: 428 KTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
+ +V + L +G+ YKFR++A + G S PS+ S P + G
Sbjct: 663 RLSVEITGLEKGTSYKFRVRALNMLGESEPSAPSRPYVVSG 703
>AL591178-3|CAH72090.1| 1437|Homo sapiens myomesin family, member 3
protein.
Length = 1437
Score = 58.8 bits (136), Expect = 1e-07
Identities = 49/150 (32%), Positives = 68/150 (45%), Gaps = 11/150 (7%)
Query: 326 RIEISITPKFSVLKI---HSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRNVSV 382
R+ S+ K S L + H A R + E N I T AF TVT P PP NV
Sbjct: 452 RVGSSVPSKASELVVMGDHDAARR-KTEIPFDLGNKITISTDAFEDTVTIP-SPPTNVHA 509
Query: 383 TRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS----RKTNVTLFDLIE 438
+ + V L WE P+ + Y +E G W +AI+S R + DL +
Sbjct: 510 SEIREAYVVLAWEEPSPRDRAPL-TYSLEKSVIGSGTW-EAISSESPVRSPRFAVLDLEK 567
Query: 439 GSEYKFRIKAESPYGMSAPSSESSPVRIPG 468
Y FR++A + YG+S PS S P+ + G
Sbjct: 568 KKSYVFRVRAMNQYGLSDPSEPSEPIALRG 597
Score = 57.6 bits (133), Expect = 2e-07
Identities = 42/163 (25%), Positives = 66/163 (40%), Gaps = 9/163 (5%)
Query: 311 TIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+I+W DG + + R +I T + + LK+ + D G Y ++ + G + V V
Sbjct: 303 SIQWFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLV 362
Query: 371 T-------APPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKA 423
P P NV + L W PP+D G + Y +E + W+
Sbjct: 363 RDAEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIAC 422
Query: 424 --ITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ L+EG Y+FR++A S G S PS S V
Sbjct: 423 HEAPGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELV 465
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/143 (30%), Positives = 64/143 (44%), Gaps = 8/143 (5%)
Query: 74 AGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWI--RTA 131
A P PG P + L D + + L WAP + G P+ Y +E + S EWI A
Sbjct: 367 AENPGAPGSPLNVRCL-DVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 425
Query: 132 PPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRL 191
P R + GL Y+FRV A++ VG S S+ S+++ + A++ L
Sbjct: 426 PGGTCR--CPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDL 483
Query: 192 EDVTALENDKVEFHVTFSGIPSP 214
+ + D E VT IPSP
Sbjct: 484 GNKITISTDAFEDTVT---IPSP 503
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 80 PGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLRPE 139
PG P + S+ ++ L+W P + G P+ GY V GS +W P +
Sbjct: 802 PGPPYDVRA-SEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTH 860
Query: 140 LVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQE 183
L ++ L+P Y F+V A+N G S +D + + + E
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHE 904
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 4/94 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP +V + S+ L WEPP G V Y V + G W K +T T+
Sbjct: 802 PGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQW-KPVTPGPISGTH 860
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + DL G Y F+++A + G+ PS + PV
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPV 894
Score = 46.4 bits (105), Expect = 6e-04
Identities = 22/86 (25%), Positives = 37/86 (43%)
Query: 295 NETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQ 354
++T+ L + G PTP I W + P+ DR + + + I D G Y +
Sbjct: 1349 DKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVF 1408
Query: 355 AKNIIGEDTAAFLVTVTAPPDPPRNV 380
KN G +T ++V D P+ +
Sbjct: 1409 VKNKYGSETGQVTISVFKHGDEPKEL 1434
Score = 45.6 bits (103), Expect = 0.001
Identities = 31/99 (31%), Positives = 46/99 (46%), Gaps = 4/99 (4%)
Query: 97 ITLKWAPATHDGGAPLRGYQVECNRLGSTEW--IRTAPPIVLRPELVLTGLEPPHKYQFR 154
+ L W + APL Y +E + +GS W I + P V P + LE Y FR
Sbjct: 517 VVLAWEEPSPRDRAPLT-YSLEKSVIGSGTWEAISSESP-VRSPRFAVLDLEKKKSYVFR 574
Query: 155 VAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLED 193
V A+N G S+ SE S+ + + A+ PP ++ D
Sbjct: 575 VRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 613
Score = 45.2 bits (102), Expect = 0.001
Identities = 35/143 (24%), Positives = 64/143 (44%), Gaps = 14/143 (9%)
Query: 332 TPKFSVLKIHSAKRSDRGEYQIQAKNIIG---EDTAAFLVTVTAPP---DPPRNVSVTRQ 385
+P+F+VL + K ++++A N G + + + PP PP V R
Sbjct: 557 SPRFAVLDLEKKKSY---VFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRD 613
Query: 386 VDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS--RKTNVTLFDLIEGSEYK 443
SV+L W+P D ++ Y + + G + W + T T+ L G EY+
Sbjct: 614 TQTSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYE 670
Query: 444 FRIKAESPYGMSAPSSESSPVRI 466
F +++ S G+ S+ + P+R+
Sbjct: 671 FCVRSVSEAGVGESSAATEPIRV 693
Score = 37.9 bits (84), Expect = 0.19
Identities = 41/145 (28%), Positives = 63/145 (43%), Gaps = 15/145 (10%)
Query: 359 IGEDTAAF----LVTVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYY- 413
+GE +AA + A P P ++ + + W+PP GG K+ Y ++ +
Sbjct: 681 VGESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHD 740
Query: 414 --RTGWN-VWLKAITSRKTNVTLFDLIEGSEYKFRIKAESPYG---MSAPSS--ESSPVR 465
W+ V + I +R V+ DL EG Y+FR +A + G +SAPSS E
Sbjct: 741 SEELDWHAVNQQPIPTRVCKVS--DLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWT 798
Query: 466 IPGRAIDMDFLAVEARIINEALTRE 490
+P D A E R + L E
Sbjct: 799 MPQPGPPYDVRASEVRATSLVLQWE 823
Score = 36.7 bits (81), Expect = 0.45
Identities = 24/111 (21%), Positives = 46/111 (41%), Gaps = 4/111 (3%)
Query: 75 GRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPI 134
G PA P + D + +++L W P L GY + ++G++EW
Sbjct: 597 GPPATLPPPAQVQAFRDTQ-TSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKP 652
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPP 185
+ + GL +Y+F V ++++ G S ++ + V A+ P
Sbjct: 653 IQGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAP 703
Score = 35.5 bits (78), Expect = 1.0
Identities = 27/119 (22%), Positives = 44/119 (36%), Gaps = 1/119 (0%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVLR 137
A P P +L+ + N + + W P GG + GY ++ + +W +
Sbjct: 698 ATPSAPYGFALLNCGK-NEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPT 756
Query: 138 PELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTA 196
++ L H Y+FR A N G S S + Q P + R +V A
Sbjct: 757 RVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQPGPPYDVRASEVRA 815
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/168 (26%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 209 SGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVT 268
SG+P+PTI W K+ + S + E T LL Q D G CTATN G +
Sbjct: 263 SGVPAPTITWTKETNALTSRGPHYNVSKEGT--LLIAQPSAQDAGAYVCTATNTVGFSSQ 320
Query: 269 KARLCLEAAPKLRYPRQYEDGLLYEI----NETIFLKTTIVGKPTPTIEWRHDGHPI--I 322
+ RL + P++ + ++ E + L G P P + W D P+ I
Sbjct: 321 EMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPI 380
Query: 323 TDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
T+ + P S L++ + D G Y+ A N G + +++ V
Sbjct: 381 TN---RYGLLPSGS-LRLAQVQVGDSGHYECTASNPAGSASHRYVLGV 424
Score = 55.2 bits (127), Expect = 1e-06
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 11/144 (7%)
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKL-RYPRQYEDGLLYEINETIFLKTTIVGKPT 309
D G C A N G A + +L + AP+L PR + E+ + L G+P
Sbjct: 22 DAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRD----VTVELGRSALLACRATGRPP 77
Query: 310 PTIEWRH-DGHPI---ITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG--EDT 363
PT+ WR DG P+ + R S P VL S D+ Y +A+N+ G +
Sbjct: 78 PTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAE 137
Query: 364 AAFLVTVTAPPDPPRNVSVTRQVD 387
A +VT APP + R ++
Sbjct: 138 ARLIVTGHAPPQIASSAPTVRVLE 161
Score = 50.4 bits (115), Expect = 3e-05
Identities = 40/170 (23%), Positives = 59/170 (34%), Gaps = 7/170 (4%)
Query: 209 SGIPSPTIAWFKDDYEIFSSR----RTAITTDESTSVLLFHQILPSDEGEIKCTATNRGG 264
+G P PT+ W + D + R R + + + VL F + P D+ C A N G
Sbjct: 73 TGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFG 132
Query: 265 HAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITD 324
+ARL + + + E + G+P P W DG P+
Sbjct: 133 KVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPG 192
Query: 325 DRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPP 374
R I L + A + G Y A N G + V PP
Sbjct: 193 SRHSIRAD---GSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPP 239
Score = 50.4 bits (115), Expect = 3e-05
Identities = 54/221 (24%), Positives = 79/221 (35%), Gaps = 17/221 (7%)
Query: 184 PPVFIKRLEDVTALENDKVEFH-VTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
PP V LE V + +G P P W KD + R +I D S L
Sbjct: 147 PPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---L 203
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLKT 302
+ L G C ATN G L ++ P++ + + L
Sbjct: 204 HLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHH---ITNEGVPASLPC 260
Query: 303 TIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGED 362
G P PTI W + + +T +++ K L I D G Y A N +G
Sbjct: 261 VASGVPAPTITWTKETN-ALTSRGPHYNVS-KEGTLLIAQPSAQDAGAYVCTATNTVGFS 318
Query: 363 TAAFLVTVTAPP----DPPRN----VSVTRQVDKSVTLDWE 395
+ ++V P + RN + VT + + VTLD E
Sbjct: 319 SQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCE 359
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/74 (29%), Positives = 31/74 (41%), Gaps = 4/74 (5%)
Query: 194 VTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFS-SRRTAITTDESTSVLLFHQILPSDE 252
VTA ++V G P P + W KD + + R + S L Q+ D
Sbjct: 346 VTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGS---LRLAQVQVGDS 402
Query: 253 GEIKCTATNRGGHA 266
G +CTA+N G A
Sbjct: 403 GHYECTASNPAGSA 416
>AK125322-1|BAC86128.1| 1685|Homo sapiens protein ( Homo sapiens
cDNA FLJ43332 fis, clone NT2RI3006340, highly similar
to Myomesin 1. ).
Length = 1685
Score = 58.8 bits (136), Expect = 1e-07
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP ++SVT V L W+PP G + Y VE G W + T +
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDM 473
LFDL EG Y FR++ + G+ P SE++ V + G +D+
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEP-SEATEVTVVGDKLDI 738
Score = 56.4 bits (130), Expect = 5e-07
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK-NIIGEDTAAFLV 368
P I+W +G P+ ++ + + + L + D G Y I+ + E +A++
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 369 T------VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P +V + + W+ PA DGG + Y ++ G + W +
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 423 AITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + + LIEG Y FR++A + G+ PS S PV
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
Score = 54.0 bits (124), Expect = 3e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 14/193 (7%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE--WIRTAPPIV 135
A PG P + S+ +++ L+W P H G P+ GY V+ + E W +
Sbjct: 1037 AVPGPPHSLKC-SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L + GL+ Y FRV A+N G S+L+ + + ++E V + + V
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDD-DGVI 1154
Query: 196 AL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+L E DK+ P +W KD S R + + + + + F + D G
Sbjct: 1155 SLNFECDKM--------TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
Query: 254 EIKCTATNRGGHA 266
C T+ G A
Sbjct: 1207 IYSCDVTDTDGIA 1219
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 52 MGNHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
MG +Y ++A+ ++ + G PA P + + D I + W DGG+P
Sbjct: 486 MGEYYE-QYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD----YIIISWKQPAVDGGSP 540
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GY ++ +G+ W + V +TGL Y FRV A+N +G S +S+
Sbjct: 541 ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600
Score = 45.6 bits (103), Expect = 0.001
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 8/156 (5%)
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
+WR ++++ +IS + + V + A + G + A + + E T+ A
Sbjct: 982 KWREANVKAVSEEAYKISNSKENMVYQFQVAAMNMAG---LGAPSAVSECFKCEEWTI-A 1037
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAITSRK 428
P PP ++ + S+ L W+PP G V Y V+ + + W L +
Sbjct: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + L EG Y FR++A + G+ PS + PV
Sbjct: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 1133
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 9/100 (9%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV---W----L 421
T APP PP +++ S+ L W+ P GG ++ Y V Y V W +
Sbjct: 929 TDRAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANV 988
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
KA++ ++ + E Y+F++ A + G+ APS+ S
Sbjct: 989 KAVSEEAYKIS--NSKENMVYQFQVAAMNMAGLGAPSAVS 1026
Score = 42.3 bits (95), Expect = 0.009
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Query: 359 IGEDTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
+GE + A VTV P P + +R D SV + WE D ++ Y +E
Sbjct: 720 VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASV 777
Query: 415 TGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
G W + + + T L+ G Y FR++A + G+S S +S + +
Sbjct: 778 AGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEV 831
Score = 40.7 bits (91), Expect = 0.027
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 6/101 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PGK IIP + D ++ + W + L GY +E + GS +W V
Sbjct: 739 PKAPGK--IIPSRNTD--TSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVK 792
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS 177
GL Y FRV A+N G S YS+ S+ + V +
Sbjct: 793 GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKA 833
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/92 (21%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 288 DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRS 346
D + + + + L + G P P + W + + +D + + + I+ +
Sbjct: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDGHCNLKFEAGRTAYFTINGVSTA 1639
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
D G+Y + KN G +T+ F V+V P + R
Sbjct: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEAR 1671
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
P FI + T E + V+ H + +G P P + W+K+ I
Sbjct: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPI 317
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 58.8 bits (136), Expect = 1e-07
Identities = 51/193 (26%), Positives = 81/193 (41%), Gaps = 12/193 (6%)
Query: 209 SGIPSPTIAWFKDDYEIF--------SSRRTAITTDESTSVLLFHQILPSDEGEIKCTAT 260
SG P P I+W D + S RT T + L F+++ ++EG+ C A
Sbjct: 90 SGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQ 149
Query: 261 NRGGHAVTKARLC-LEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGH 319
N G K L + AAP++R + + + +T L + G P P I W +
Sbjct: 150 NTLGKDEMKVHLTVITAAPRIRQSNKTNKRI--KAGDTAVLDCEVTGDPKPKIFWLLPSN 207
Query: 320 PIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPRN 379
+I+ + S L I+ K D GEY A+N G+DT + + V + P
Sbjct: 208 DMISFSIDRYTFHANGS-LTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLING 266
Query: 380 VSVTRQVDKSVTL 392
+ R V K+ +
Sbjct: 267 LYTNRTVIKATAV 279
Score = 58.0 bits (134), Expect = 2e-07
Identities = 53/224 (23%), Positives = 83/224 (37%), Gaps = 14/224 (6%)
Query: 152 QFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVTALENDKVEFHVTFSGI 211
++R AA N VG Y E +L + Q+P + V + + + H GI
Sbjct: 435 KYRCAARNKVG---YIEKLVILEIG-----QKPVILTYAPGTVKGISGESLSLHCVSDGI 486
Query: 212 PSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEGEIKCTATNRGGHAVTKA 270
P P I W Y + + L+ + D G C A N GH +
Sbjct: 487 PKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 546
Query: 271 RLCLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEIS 330
+ + A P R + ++ L +G P P I W H +++ E +
Sbjct: 547 PVMIVAYPP-RITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERT 605
Query: 331 ITPKF----SVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTV 370
+ L I + + SD G Y+ AKN +G D AA + V
Sbjct: 606 HGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 649
Score = 53.2 bits (122), Expect = 5e-06
Identities = 38/169 (22%), Positives = 68/169 (40%), Gaps = 3/169 (1%)
Query: 195 TALENDKVEFHVTFSGIPSPTIAW-FKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
TA+ + K F G PSP + W D+ + + + T L + SD
Sbjct: 277 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 336
Query: 254 EIKCTATNRGGHAVTKARL-CLEAAPKLRYPRQYEDGLLYEINETIFLKTTIVGKPTPTI 312
+ C A N GG +V +L LE + + + + ++ ++ ++ L ++ G P P I
Sbjct: 337 DFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEI 396
Query: 313 EW-RHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIG 360
W +G + + I R D G+Y+ A+N +G
Sbjct: 397 IWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 445
Score = 45.6 bits (103), Expect = 0.001
Identities = 52/203 (25%), Positives = 81/203 (39%), Gaps = 16/203 (7%)
Query: 192 EDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAIT-TDESTSVLLFHQILPS 250
E + A + + G P P I W + FS+ + S + +
Sbjct: 372 EKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTRE 431
Query: 251 DEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEIN-ETIFLKTTIVGKPT 309
D G+ +C A N+ G+ L + P + Y G + I+ E++ L G P
Sbjct: 432 DAGKYRCAARNKVGYIEKLVILEIGQKPVIL---TYAPGTVKGISGESLSLHCVSDGIPK 488
Query: 310 PTIEWRHDGHPIITDDRIEIS---ITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAF 366
P I+W ++ DR +I+ I L I A DRG Y +A+N +G
Sbjct: 489 PNIKWTMPSGYVV--DRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 546
Query: 367 LVTVTA-PP----DPPRNVSVTR 384
V + A PP PPR++ VTR
Sbjct: 547 PVMIVAYPPRITNRPPRSI-VTR 568
>AJ621424-1|CAF18565.1| 1685|Homo sapiens myomesin 1 protein.
Length = 1685
Score = 58.8 bits (136), Expect = 1e-07
Identities = 34/103 (33%), Positives = 49/103 (47%), Gaps = 5/103 (4%)
Query: 374 PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLKAITS---RKTN 430
P PP ++SVT V L W+PP G + Y VE G W + T +
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 431 VTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRIPGRAIDM 473
LFDL EG Y FR++ + G+ P SE++ V + G +D+
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEP-SEATEVTVVGDKLDI 738
Score = 56.4 bits (130), Expect = 5e-07
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
Query: 310 PTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAK-NIIGEDTAAFLV 368
P I+W +G P+ ++ + + + L + D G Y I+ + E +A++
Sbjct: 439 PEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVF 498
Query: 369 T------VTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNVWLK 422
+ P P +V + + W+ PA DGG + Y ++ G + W +
Sbjct: 499 VRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQ 558
Query: 423 AITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + + LIEG Y FR++A + G+ PS S PV
Sbjct: 559 CNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPV 602
Score = 54.0 bits (124), Expect = 3e-06
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 14/193 (7%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTE--WIRTAPPIV 135
A PG P + S+ +++ L+W P H G P+ GY V+ + E W +
Sbjct: 1037 AVPGPPHSLKC-SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAI 1095
Query: 136 LRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSSDRASQEPPVFIKRLEDVT 195
L + GL+ Y FRV A+N G S+L+ + + ++E V + + V
Sbjct: 1096 KNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDD-DGVI 1154
Query: 196 AL--ENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVLLFHQILPSDEG 253
+L E DK+ P +W KD S R + + + + + F + D G
Sbjct: 1155 SLNFECDKM--------TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLG 1206
Query: 254 EIKCTATNRGGHA 266
C T+ G A
Sbjct: 1207 IYSCDVTDTDGIA 1219
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 5/120 (4%)
Query: 52 MGNHYSASHNAFKPRKNVHWKSAGRPAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAP 111
MG +Y ++A+ ++ + G PA P + + D I + W DGG+P
Sbjct: 486 MGEYYE-QYSAYVFVRDADAEIEGAPAAPLDVKCLEANKD----YIIISWKQPAVDGGSP 540
Query: 112 LRGYQVECNRLGSTEWIRTAPPIVLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
+ GY ++ +G+ W + V +TGL Y FRV A+N +G S +S+
Sbjct: 541 ILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSE 600
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 9/100 (9%)
Query: 369 TVTAPPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYRTGWNV---W----L 421
T APP PP +++ S+ L W+ P GG ++ Y V Y V W +
Sbjct: 929 TDRAPPSPPCDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANV 988
Query: 422 KAITSRKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSES 461
KA++ ++ +L E Y+F++ A + G+ APS+ S
Sbjct: 989 KAVSEEAYKIS--NLKENMVYQFQVAAMNMAGLGAPSAVS 1026
Score = 44.8 bits (101), Expect = 0.002
Identities = 37/156 (23%), Positives = 66/156 (42%), Gaps = 8/156 (5%)
Query: 313 EWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGEDTAAFLVTVTA 372
+WR ++++ +IS + V + A + G + A + + E T+ A
Sbjct: 982 KWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAG---LGAPSAVSECFKCEEWTI-A 1037
Query: 373 PPDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEY--YRTGWNVW--LKAITSRK 428
P PP ++ + S+ L W+PP G V Y V+ + + W L +
Sbjct: 1038 VPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKN 1097
Query: 429 TNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPV 464
+ + L EG Y FR++A + G+ PS + PV
Sbjct: 1098 VYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPV 1133
Score = 42.3 bits (95), Expect = 0.009
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 8/114 (7%)
Query: 359 IGEDTAAFLVTVTAP----PDPPRNVSVTRQVDKSVTLDWEPPADDGGCKVGNYIVEYYR 414
+GE + A VTV P P + +R D SV + WE D ++ Y +E
Sbjct: 720 VGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKD--AKELVGYYIEASV 777
Query: 415 TGWNVWLKAITS--RKTNVTLFDLIEGSEYKFRIKAESPYGMSAPSSESSPVRI 466
G W + + + T L+ G Y FR++A + G+S S +S + +
Sbjct: 778 AGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEV 831
Score = 41.1 bits (92), Expect = 0.021
Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 288 DGLLYEINETIFLKTTIVGKPTPTIEWRHDGHPIITDDRIEISITP-KFSVLKIHSAKRS 346
D + + + + L + G P P + W + + +DD + + + I+ +
Sbjct: 1580 DVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTA 1639
Query: 347 DRGEYQIQAKNIIGEDTAAFLVTVTAPPDPPR 378
D G+Y + KN G +T+ F V+V P + R
Sbjct: 1640 DSGKYGLVVKNKYGSETSDFTVSVFIPEEEAR 1671
Score = 40.7 bits (91), Expect = 0.027
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 6/101 (5%)
Query: 77 PAPPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGSTEWIRTAPPIVL 136
P PGK IIP + D ++ + W + L GY +E + GS +W V
Sbjct: 739 PKAPGK--IIPSRNTD--TSVVVSWEESKD--AKELVGYYIEASVAGSGKWEPCNNNPVK 792
Query: 137 RPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSDVLTVSS 177
GL Y FRV A+N G S YS+ S+ + V +
Sbjct: 793 GSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKA 833
Score = 34.3 bits (75), Expect = 2.4
Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 4/97 (4%)
Query: 78 APPGKPQIIPILSDDEPNAITLKWAPATHDGGAPLRGYQVECNRLGST---EWIRTAPPI 134
APP P I L +++ L W GGA + GY V + +W
Sbjct: 932 APPSPPCDITCLESFR-DSMVLGWKQPDKTGGAEITGYYVNYREVIDGVPGKWREANVKA 990
Query: 135 VLRPELVLTGLEPPHKYQFRVAALNDVGHSNYSELSD 171
V ++ L+ YQF+VAA+N G S +S+
Sbjct: 991 VSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEI 225
P FI + T E + V+ H + +G P P + W+K+ I
Sbjct: 277 PEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPI 317
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSV-LL 243
P F K + D+ +E F G P P + WFKDD I SR I DE + L+
Sbjct: 195 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 254
Query: 244 FHQILPSDEGEIKCTATNRGGHAVTKARLCLE 275
+ D+ + C A N G A A L +E
Sbjct: 255 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 286
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 663 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 717
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 718 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 775
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 776 ERGNVRLSVIPTP 788
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 754
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 755 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 794
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 663 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 717
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 718 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 775
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 776 ERGNVRLSVIPTP 788
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 754
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 755 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 794
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 663 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 717
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 718 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 775
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 776 ERGNVRLSVIPTP 788
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 754
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 755 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 794
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 543 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 602
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 603 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 657
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 658 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 715
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 716 ERGNVRLSVIPTP 728
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 635 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 694
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 695 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 734
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 603 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 662
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 663 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 717
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 718 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 775
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 776 ERGNVRLSVIPTP 788
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 695 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 754
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 755 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 794
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/193 (25%), Positives = 77/193 (39%), Gaps = 10/193 (5%)
Query: 185 PVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKD---DYEIFSSRRTAITTDESTSV 241
P F K D+T G P+P IAW KD D+ RR + ++
Sbjct: 181 PSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFF 240
Query: 242 LLFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPRQYEDGLLYEINETIFLK 301
++ +I D G CTA N G A L + P + R D + + ET L+
Sbjct: 241 IVDVKI--EDIGVYSCTAQNSAGSISANATLTVLETPS--FLRPLLDRTVTK-GETAVLQ 295
Query: 302 TTIVGKPTPTIEWRHDGHPIITDDRIEISITPKFSVLKIHSAKRSDRGEYQIQAKNIIGE 361
G P P + W D P++ +R + + +L I + SD G+Y + N +G
Sbjct: 296 CIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQ--LLIIVDSDVSDAGKYTCEMSNTLGT 353
Query: 362 DTAAFLVTVTAPP 374
+ ++V P
Sbjct: 354 ERGNVRLSVIPTP 366
Score = 37.9 bits (84), Expect = 0.19
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 2/102 (1%)
Query: 183 EPPVFIKRLEDVTALENDKVEFHVTFSGIPSPTIAWFKDDYEIFSSRRTAITTDESTSVL 242
E P F++ L D T + + G P P + W KDD + + R ++
Sbjct: 273 ETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLII 332
Query: 243 LFHQILPSDEGEIKCTATNRGGHAVTKARLCLEAAPKLRYPR 284
+ + SD G+ C +N G RL + P P+
Sbjct: 333 VDSDV--SDAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQ 372
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.314 0.131 0.381
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 154,844,572
Number of Sequences: 224733
Number of extensions: 6739663
Number of successful extensions: 26698
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 373
Number of HSP's successfully gapped in prelim test: 656
Number of HSP's that attempted gapping in prelim test: 16434
Number of HSP's gapped (non-prelim): 6414
length of query: 1081
length of database: 73,234,838
effective HSP length: 98
effective length of query: 983
effective length of database: 51,211,004
effective search space: 50340416932
effective search space used: 50340416932
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 70 (32.3 bits)
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