Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000587-TA|BGIBMGA000587-PA|IPR000421|Coagulation factor
5/8 type, C-terminal, IPR001245|Tyrosine protein kinase,
IPR011009|Protein kinase-like, IPR008979|Galactose-binding like,
IPR008266|Tyrosine protein kinase, active site, IPR000719|Protein
kinase
(965 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D576E5 Cluster: PREDICTED: similar to CG33531-PA... 764 0.0
UniRef50_Q8T0Z7 Cluster: Tyrosine kinase-like protein; n=1; Bomb... 473 e-131
UniRef50_UPI00015B4909 Cluster: PREDICTED: similar to GA16357-PA... 462 e-128
UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to prenylcyst... 359 2e-97
UniRef50_UPI0000519EF1 Cluster: PREDICTED: similar to CG31640-PA... 356 2e-96
UniRef50_Q59DZ7 Cluster: CG33531-PA; n=6; Sophophora|Rep: CG3353... 355 2e-96
UniRef50_Q17HL3 Cluster: Discoidin domain receptor; n=3; Culicid... 349 2e-94
UniRef50_Q9VMG2 Cluster: CG31640-PA; n=2; Drosophila melanogaste... 345 3e-93
UniRef50_UPI00015B629F Cluster: PREDICTED: similar to CG33531-PA... 322 2e-86
UniRef50_UPI0000D576E4 Cluster: PREDICTED: similar to CG33531-PA... 316 1e-84
UniRef50_UPI0000DB7238 Cluster: PREDICTED: similar to Discoidin ... 293 2e-77
UniRef50_UPI00015B629D Cluster: PREDICTED: similar to CG33531-PA... 290 1e-76
UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, membe... 277 1e-72
UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing ... 269 2e-70
UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2 ... 264 8e-69
UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate dis... 264 1e-68
UniRef50_UPI0000E48069 Cluster: PREDICTED: hypothetical protein;... 257 9e-67
UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome s... 257 1e-66
UniRef50_UPI0000DB6BCC Cluster: PREDICTED: similar to Discoidin ... 248 4e-64
UniRef50_UPI00015B46B5 Cluster: PREDICTED: similar to CG33531-PA... 244 1e-62
UniRef50_UPI000065F9C5 Cluster: Epithelial discoidin domain-cont... 238 5e-61
UniRef50_Q70W12 Cluster: Discoidin receptor; n=1; Ciona intestin... 237 1e-60
UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3; ... 225 4e-57
UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor precu... 206 2e-51
UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor precu... 204 7e-51
UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5; Caenorha... 201 6e-50
UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|R... 199 3e-49
UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3; ... 197 1e-48
UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2; ... 195 5e-48
UniRef50_P04629 Cluster: High affinity nerve growth factor recep... 195 5e-48
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 194 7e-48
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 192 3e-47
UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane r... 188 6e-46
UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane r... 188 6e-46
UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase recepto... 187 1e-45
UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor; ... 186 3e-45
UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1... 177 1e-42
UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1... 176 2e-42
UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming pr... 175 5e-42
UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor p... 175 6e-42
UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor p... 174 8e-42
UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2; ... 174 1e-41
UniRef50_Q17305 Cluster: G01D9.2 protein; n=3; Caenorhabditis|Re... 174 1e-41
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 172 3e-41
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 172 3e-41
UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca CG... 172 4e-41
UniRef50_P14616 Cluster: Insulin receptor-related protein precur... 172 4e-41
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 172 4e-41
UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror CG4926... 171 6e-41
UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2; ... 171 6e-41
UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|... 171 6e-41
UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1; ... 171 6e-41
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 171 6e-41
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 171 8e-41
UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 171 1e-40
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 171 1e-40
UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin re... 170 1e-40
UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 170 2e-40
UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 170 2e-40
UniRef50_P42159 Cluster: Class II receptor tyrosine kinase; n=5;... 170 2e-40
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 169 3e-40
UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2; ... 169 3e-40
UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1; ... 169 4e-40
UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 168 5e-40
UniRef50_Q25410 Cluster: Putative molluscan insulin-related pept... 168 5e-40
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 168 5e-40
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 168 7e-40
UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ... 167 1e-39
UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-li... 167 1e-39
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 167 2e-39
UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane r... 166 3e-39
UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p, ... 165 4e-39
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 165 4e-39
UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|R... 165 4e-39
UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;... 165 5e-39
UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK sp... 164 1e-38
UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-onco... 163 2e-38
UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte ... 162 4e-38
UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin re... 162 4e-38
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 162 4e-38
UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor... 162 4e-38
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 162 4e-38
UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA;... 161 6e-38
UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; ... 161 8e-38
UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;... 161 8e-38
UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine p... 161 1e-37
UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor ... 161 1e-37
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 159 3e-37
UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra... 159 3e-37
UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2; ... 157 1e-36
UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic... 157 2e-36
UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gamb... 157 2e-36
UniRef50_Q9Y1X7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 156 2e-36
UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to ENSANGP000... 155 7e-36
UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2; ... 154 1e-35
UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella ve... 154 1e-35
UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3 ... 154 1e-35
UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase ... 154 1e-35
UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC 2.7... 154 1e-35
UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane r... 153 2e-35
UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5; ... 153 3e-35
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 153 3e-35
UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var... 153 3e-35
UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase ... 153 3e-35
UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC 2.7... 153 3e-35
UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1 p... 152 4e-35
UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3; Eutheria... 151 7e-35
UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor prec... 151 7e-35
UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca precur... 151 7e-35
UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan re... 151 9e-35
UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre... 151 9e-35
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 151 1e-34
UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-li... 151 1e-34
UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:... 151 1e-34
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 150 2e-34
UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250... 150 2e-34
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 149 3e-34
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 149 4e-34
UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella ve... 149 4e-34
UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin re... 149 5e-34
UniRef50_Q29JN3 Cluster: GA21826-PA; n=2; Endopterygota|Rep: GA2... 149 5e-34
UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Re... 149 5e-34
UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein ... 148 6e-34
UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 148 6e-34
UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=... 148 6e-34
UniRef50_Q179Z3 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 148 8e-34
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 147 1e-33
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 147 1e-33
UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery... 147 1e-33
UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2 pre... 147 1e-33
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 146 2e-33
UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homol... 146 2e-33
UniRef50_UPI0000D56AE3 Cluster: PREDICTED: similar to CG1594-PA;... 146 3e-33
UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77; E... 145 4e-33
UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9; Cl... 144 8e-33
UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|... 144 8e-33
UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta ... 144 8e-33
UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n... 144 8e-33
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 144 1e-32
UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella ve... 144 1e-32
UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12; Euar... 144 1e-32
UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor... 144 1e-32
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 144 1e-32
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 144 1e-32
UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:... 143 2e-32
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 142 4e-32
UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2... 142 4e-32
UniRef50_UPI00015B6363 Cluster: PREDICTED: similar to tyrosine p... 142 5e-32
UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to ENSANGP000... 142 5e-32
UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,... 142 5e-32
UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol... 142 5e-32
UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1; ... 142 5e-32
UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|R... 141 7e-32
UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precu... 141 7e-32
UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47; E... 141 7e-32
UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberite... 141 9e-32
UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=... 141 9e-32
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 141 9e-32
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 140 1e-31
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 140 1e-31
UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 140 1e-31
UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep: Zgc:1... 140 1e-31
UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56; n... 140 1e-31
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 140 1e-31
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 140 1e-31
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 140 2e-31
UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor precu... 140 2e-31
UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2... 140 2e-31
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 140 2e-31
UniRef50_Q26614 Cluster: Fibroblast growth factor receptor precu... 140 2e-31
UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1 pre... 140 2e-31
UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA... 139 3e-31
UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4... 139 3e-31
UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n... 139 4e-31
UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor... 139 4e-31
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 138 5e-31
UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA... 138 5e-31
UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6; Eume... 138 5e-31
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 138 7e-31
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 138 7e-31
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 138 7e-31
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 138 7e-31
UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family... 138 9e-31
UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin re... 138 9e-31
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 138 9e-31
UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor recep... 137 1e-30
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 137 1e-30
UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO pr... 137 1e-30
UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming pr... 137 1e-30
UniRef50_P52333 Cluster: Tyrosine-protein kinase JAK3; n=17; Eut... 137 1e-30
UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1 pre... 137 1e-30
UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24; Euteleo... 137 1e-30
UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n... 137 2e-30
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 137 2e-30
UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protei... 136 2e-30
UniRef50_UPI0000DB7B4C Cluster: PREDICTED: similar to hopscotch ... 136 2e-30
UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precurs... 136 2e-30
UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2; Culicidae... 136 2e-30
UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3; Culicidae|... 136 2e-30
UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n... 136 2e-30
UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella ve... 136 2e-30
UniRef50_O60674 Cluster: Tyrosine-protein kinase JAK2; n=48; Eut... 136 2e-30
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 136 2e-30
UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=3... 136 2e-30
UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 136 3e-30
UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3; ... 136 3e-30
UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase... 136 4e-30
UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus ... 136 4e-30
UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella ve... 136 4e-30
UniRef50_P00533 Cluster: Epidermal growth factor receptor precur... 135 5e-30
UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosin... 135 6e-30
UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome s... 135 6e-30
UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor... 135 6e-30
UniRef50_UPI0000D563AD Cluster: PREDICTED: similar to CG3969-PA,... 134 8e-30
UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephr... 134 8e-30
UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111; Euteleo... 134 8e-30
UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming pr... 134 8e-30
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 134 1e-29
UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Re... 134 1e-29
UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:... 134 1e-29
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 134 1e-29
UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precurs... 134 1e-29
UniRef50_Q9PTN6 Cluster: Tyrosine-protein kinase; n=9; Euteleost... 134 1e-29
UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome sh... 134 1e-29
UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep... 134 1e-29
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 134 1e-29
UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep: E... 133 2e-29
UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13; Euteleo... 133 2e-29
UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 133 3e-29
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 133 3e-29
UniRef50_A7SE14 Cluster: Predicted protein; n=4; Nematostella ve... 133 3e-29
UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack CG1499... 132 3e-29
UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep: CG1499... 132 3e-29
UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin... 132 3e-29
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 132 4e-29
UniRef50_UPI0000F1D883 Cluster: PREDICTED: hypothetical protein;... 132 4e-29
UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona ... 132 4e-29
UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;... 132 6e-29
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 132 6e-29
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 131 8e-29
UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep... 131 8e-29
UniRef50_A7RGV3 Cluster: Predicted protein; n=1; Nematostella ve... 131 8e-29
UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle spe... 131 1e-28
UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome s... 131 1e-28
UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora... 131 1e-28
UniRef50_Q674V1 Cluster: Vascular endothelial growth factor rece... 130 1e-28
UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella ve... 130 1e-28
UniRef50_P21860 Cluster: Receptor tyrosine-protein kinase erbB-3... 130 1e-28
UniRef50_P04412 Cluster: Epidermal growth factor receptor precur... 130 1e-28
UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to tyrosine-p... 130 2e-28
UniRef50_Q4SWL0 Cluster: Ephrin receptor; n=3; Tetraodontidae|Re... 130 2e-28
UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1; ... 130 2e-28
UniRef50_Q4H3M5 Cluster: Ephrin receptor; n=1; Ciona intestinali... 130 2e-28
UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1 ... 130 2e-28
UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=2... 130 2e-28
UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=1... 130 2e-28
UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;... 130 2e-28
UniRef50_UPI000051AB92 Cluster: PREDICTED: similar to Fak-like t... 130 2e-28
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 130 2e-28
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 130 2e-28
UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homol... 130 2e-28
UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=3... 130 2e-28
UniRef50_Q4SP88 Cluster: Ephrin receptor; n=2; Tetraodon nigrovi... 129 3e-28
UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome sh... 129 3e-28
UniRef50_Q9Y1Y7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 129 3e-28
UniRef50_Q86LZ8 Cluster: Insulin receptor protein kinase; n=2; S... 129 3e-28
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 129 3e-28
UniRef50_Q25177 Cluster: Receptor protein-tyrosine kinase; n=2; ... 129 4e-28
UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;... 129 4e-28
UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella ve... 129 4e-28
UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41... 129 4e-28
UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=1... 129 4e-28
UniRef50_UPI00006A1E7A Cluster: Non-receptor tyrosine-protein ki... 128 5e-28
UniRef50_UPI000065FEDC Cluster: Activated CDC42 kinase 1 (EC 2.7... 128 5e-28
UniRef50_Q6SAJ2 Cluster: Epidermal growth factor receptor; n=11;... 128 5e-28
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 128 5e-28
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 128 5e-28
UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=5... 128 5e-28
UniRef50_UPI000065DACB Cluster: Homolog of Homo sapiens "Splice ... 128 7e-28
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 128 7e-28
UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga... 128 7e-28
UniRef50_Q24327 Cluster: Gp160-Dtrk precursor; n=4; Sophophora|R... 128 7e-28
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 128 7e-28
UniRef50_Q6W5B1 Cluster: TEL/JAK2 fusion protein; n=4; Danio rer... 128 9e-28
UniRef50_Q4H3M4 Cluster: Ephrin receptor; n=2; Ciona intestinali... 128 9e-28
UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella ve... 128 9e-28
UniRef50_UPI0000660568 Cluster: Ephrin type-B receptor 2 precurs... 127 1e-27
UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome sh... 127 1e-27
UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome sh... 127 1e-27
UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whol... 127 1e-27
UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella ve... 127 1e-27
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 127 1e-27
UniRef50_UPI0000E48358 Cluster: PREDICTED: hypothetical protein;... 127 2e-27
UniRef50_UPI0000E47A46 Cluster: PREDICTED: similar to ret protei... 127 2e-27
UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: E... 127 2e-27
UniRef50_Q17IF1 Cluster: Receptor protein tyrosine kinase; n=1; ... 127 2e-27
UniRef50_Q24592 Cluster: Tyrosine-protein kinase hopscotch; n=2;... 127 2e-27
UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Eph... 126 2e-27
UniRef50_UPI0000F1F8B4 Cluster: PREDICTED: hypothetical protein;... 126 3e-27
UniRef50_UPI00006A0A62 Cluster: High affinity nerve growth facto... 126 3e-27
UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1; ... 126 3e-27
UniRef50_O45232 Cluster: Putative uncharacterized protein ark-1;... 126 3e-27
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 126 4e-27
UniRef50_UPI0000E47C0F Cluster: PREDICTED: similar to focal adhe... 125 5e-27
UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 125 5e-27
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 125 5e-27
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 125 5e-27
UniRef50_Q5BXN9 Cluster: SJCHGC05493 protein; n=1; Schistosoma j... 125 7e-27
UniRef50_UPI0000DB6C79 Cluster: PREDICTED: similar to PTK7 prote... 124 9e-27
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 124 9e-27
UniRef50_UPI0000D55944 Cluster: PREDICTED: similar to CG8967-PA;... 124 1e-26
UniRef50_Q4RU24 Cluster: Chromosome 12 SCAF14996, whole genome s... 124 1e-26
UniRef50_O76411 Cluster: Suppressor of constitutive dauer format... 124 1e-26
UniRef50_UPI00015B5A01 Cluster: PREDICTED: similar to protein ki... 123 2e-26
UniRef50_Q68KJ7 Cluster: HER2; n=3; Amniota|Rep: HER2 - Felis si... 123 2e-26
UniRef50_A7RL50 Cluster: Predicted protein; n=1; Nematostella ve... 123 2e-26
UniRef50_Q15516 Cluster: Tyrosine kinase; n=1; Homo sapiens|Rep:... 123 2e-26
UniRef50_UPI00015B4DC3 Cluster: PREDICTED: similar to receptor t... 123 3e-26
UniRef50_P29597 Cluster: Non-receptor tyrosine-protein kinase TY... 123 3e-26
UniRef50_UPI00015B6341 Cluster: PREDICTED: similar to KLG; n=1; ... 122 4e-26
UniRef50_Q4SR43 Cluster: Chromosome 11 SCAF14528, whole genome s... 122 4e-26
UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep: ... 122 4e-26
UniRef50_Q5DM52 Cluster: Receptor tyrosine kinase Torso-like pro... 122 4e-26
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 122 4e-26
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 122 5e-26
UniRef50_Q4T272 Cluster: Chromosome undetermined SCAF10323, whol... 122 5e-26
UniRef50_Q9TX48 Cluster: 220 kDa ABL-related protein tyrosine ki... 122 5e-26
UniRef50_Q6SAA3 Cluster: Epidermal growth factor receptor; n=39;... 122 6e-26
UniRef50_Q6ZMQ8-3 Cluster: Isoform 3 of Q6ZMQ8 ; n=6; Tetrapoda|... 121 8e-26
UniRef50_Q6ZMQ8 Cluster: Serine/threonine-protein kinase LMTK1; ... 121 8e-26
UniRef50_UPI0000EB1EAB Cluster: Serine/threonine-protein kinase ... 121 1e-25
UniRef50_Q6GPK5 Cluster: Tyrosine-protein kinase; n=4; Euteleost... 121 1e-25
UniRef50_Q8T0W6 Cluster: Putative insulin receptor precursor; n=... 121 1e-25
UniRef50_Q13470 Cluster: Non-receptor tyrosine-protein kinase TN... 121 1e-25
UniRef50_UPI0000E49426 Cluster: PREDICTED: hypothetical protein;... 120 1e-25
UniRef50_Q9GRH1 Cluster: Tyrosine-protein kinase receptor; n=4; ... 120 1e-25
UniRef50_Q70W09 Cluster: Receptor tyrosine kinase VIII; n=1; Cio... 120 1e-25
UniRef50_Q16RK6 Cluster: Receptor protein tyrosine kinase; n=1; ... 120 1e-25
UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3; ... 120 1e-25
UniRef50_A7SP77 Cluster: Predicted protein; n=1; Nematostella ve... 120 2e-25
UniRef50_Q8IWU2 Cluster: Serine/threonine-protein kinase LMTK2 p... 120 2e-25
UniRef50_UPI0000D8BE91 Cluster: UPI0000D8BE91 related cluster; n... 120 3e-25
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 120 3e-25
UniRef50_UPI0000F306DC Cluster: Serine/threonine-protein kinase ... 119 3e-25
UniRef50_Q4T1R9 Cluster: Chromosome 4 SCAF10492, whole genome sh... 119 3e-25
UniRef50_Q4S8H3 Cluster: Chromosome 2 SCAF14705, whole genome sh... 119 4e-25
UniRef50_Q4H3N3 Cluster: Epidermal growth factor receptor; n=1; ... 119 4e-25
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 119 4e-25
UniRef50_Q96Q04 Cluster: Serine/threonine-protein kinase LMTK3 p... 118 6e-25
UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kin... 118 8e-25
UniRef50_Q9PWD1 Cluster: Tyrosine-protein kinase; n=3; Tetraodon... 118 8e-25
UniRef50_Q8WSM2 Cluster: Receptor tyrosine kinase; n=1; Schistos... 118 8e-25
UniRef50_Q6SAW1 Cluster: Epidermal growth factor receptor; n=70;... 118 8e-25
UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4; Caenorhabd... 118 1e-24
UniRef50_Q5G254 Cluster: Erbb3; n=6; Danio rerio|Rep: Erbb3 - Da... 118 1e-24
UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15 ... 118 1e-24
UniRef50_Q9I9L1 Cluster: Arg protein-tyrosine kinase; n=12; Tetr... 117 1e-24
UniRef50_Q4S1M5 Cluster: Chromosome 6 SCAF14768, whole genome sh... 117 1e-24
UniRef50_Q4L0H7 Cluster: Insulin receptor tyrosine kinase; n=2; ... 117 1e-24
UniRef50_Q26566 Cluster: Epidermal growth factor receptor precur... 117 1e-24
UniRef50_P34925 Cluster: Tyrosine-protein kinase RYK precursor; ... 117 1e-24
UniRef50_Q3TYD6 Cluster: Serine/threonine-protein kinase LMTK2 p... 117 1e-24
UniRef50_Q9UF33 Cluster: Ephrin type-A receptor 6 precursor; n=5... 117 1e-24
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 117 2e-24
UniRef50_A7S934 Cluster: Predicted protein; n=4; Nematostella ve... 117 2e-24
UniRef50_P23458 Cluster: Tyrosine-protein kinase JAK1; n=55; Eut... 117 2e-24
UniRef50_Q4S883 Cluster: Chromosome 3 SCAF14707, whole genome sh... 116 2e-24
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 116 2e-24
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 116 3e-24
UniRef50_O76809 Cluster: Receptor tyrosine kinase HTK30; n=1; Hy... 116 3e-24
UniRef50_UPI0000F2DD16 Cluster: PREDICTED: similar to cellular-r... 115 7e-24
UniRef50_Q4RH14 Cluster: Chromosome undetermined SCAF15074, whol... 115 7e-24
UniRef50_Q9Y1Y4 Cluster: Tyrosine-protein kinase; n=1; Ephydatia... 114 9e-24
UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 114 9e-24
UniRef50_Q5JZY3 Cluster: Ephrin type-A receptor 10 precursor; n=... 114 9e-24
UniRef50_P07333 Cluster: Macrophage colony-stimulating factor 1 ... 114 9e-24
UniRef50_UPI000069F079 Cluster: Serine/threonine-protein kinase ... 114 1e-23
UniRef50_Q4RXB0 Cluster: Chromosome 11 SCAF14979, whole genome s... 114 1e-23
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 114 1e-23
UniRef50_Q7YZH5 Cluster: MBTK3; n=1; Monosiga brevicollis|Rep: M... 114 1e-23
UniRef50_Q7YXV8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 114 1e-23
UniRef50_Q7Q890 Cluster: ENSANGP00000005167; n=1; Anopheles gamb... 114 1e-23
UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2; Anthomedu... 113 2e-23
UniRef50_Q0MQ66 Cluster: Putative uncharacterized protein; n=5; ... 113 2e-23
UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Re... 113 2e-23
UniRef50_UPI00005A2D48 Cluster: PREDICTED: similar to EPH recept... 113 3e-23
UniRef50_Q9XYS4 Cluster: Tyrosine kinase receptor HTK32; n=1; Hy... 113 3e-23
UniRef50_Q7Z1L9 Cluster: Neurite outgrowth regulated kinase; n=1... 113 3e-23
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 113 3e-23
UniRef50_UPI0000E4A99A Cluster: PREDICTED: similar to tyrosine k... 112 4e-23
UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2; ... 112 4e-23
UniRef50_Q86MD7 Cluster: EGF receptor; n=1; Echinococcus multilo... 112 4e-23
UniRef50_P18475 Cluster: Tyrosine-protein kinase receptor torso ... 112 4e-23
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 112 5e-23
UniRef50_A7RX97 Cluster: Predicted protein; n=1; Nematostella ve... 112 5e-23
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 112 5e-23
UniRef50_UPI0000F1DBB6 Cluster: PREDICTED: hypothetical protein;... 111 7e-23
UniRef50_Q4SF69 Cluster: Chromosome undetermined SCAF14608, whol... 111 7e-23
UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu... 111 7e-23
UniRef50_UPI0000E257E1 Cluster: PREDICTED: similar to tyrosine k... 111 1e-22
UniRef50_Q9U8U8 Cluster: VEGFR-like; n=1; Branchiostoma belcheri... 111 1e-22
UniRef50_Q7Q0U2 Cluster: ENSANGP00000012311; n=1; Anopheles gamb... 111 1e-22
UniRef50_UPI0000DB7A04 Cluster: PREDICTED: similar to lemur tyro... 110 2e-22
UniRef50_Q25199 Cluster: Tyrosine kinase receptor; n=7; Hydra|Re... 110 2e-22
UniRef50_Q19238 Cluster: Putative tyrosine-protein kinase F09A5.... 110 2e-22
UniRef50_P24348 Cluster: Receptor tyrosine-protein kinase let-23... 110 2e-22
UniRef50_O15197 Cluster: Ephrin type-B receptor 6 precursor; n=2... 110 2e-22
UniRef50_Q9VLQ8 Cluster: CG8222-PA, isoform A; n=8; Sophophora|R... 110 2e-22
UniRef50_Q8T4M0 Cluster: VEGFR-A splice form A; n=4; Diptera|Rep... 110 2e-22
UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 110 2e-22
UniRef50_Q9XW34 Cluster: Putative uncharacterized protein; n=3; ... 109 3e-22
UniRef50_O61460 Cluster: Ephrin receptor 1 precursor; n=3; Caeno... 109 4e-22
UniRef50_Q8MY85 Cluster: Fibroblast growth factor receptor 2 pre... 109 4e-22
UniRef50_A4IIX3 Cluster: Putative uncharacterized protein; n=1; ... 109 5e-22
UniRef50_Q9I8N6 Cluster: Macrophage colony-stimulating factor 1 ... 109 5e-22
UniRef50_Q61B52 Cluster: Putative uncharacterized protein CBG134... 108 6e-22
UniRef50_Q21041 Cluster: Putative uncharacterized protein ver-4;... 108 6e-22
UniRef50_O17391 Cluster: Protein kinase protein 9, isoform b; n=... 108 6e-22
UniRef50_UPI00006A0D3B Cluster: Tyrosine protein-kinase STYK1 (E... 108 8e-22
UniRef50_Q640T5 Cluster: Tyrosine-protein kinase receptor; n=2; ... 108 8e-22
UniRef50_Q4SJQ3 Cluster: Tyrosine-protein kinase receptor; n=1; ... 108 8e-22
UniRef50_Q1HTP1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 108 8e-22
UniRef50_Q4H3A3 Cluster: Janus kinase; n=1; Ciona intestinalis|R... 108 8e-22
UniRef50_Q8UVR8 Cluster: Macrophage colony-stimulating factor 1 ... 108 8e-22
UniRef50_UPI00004CFD13 Cluster: Serine/threonine-protein kinase ... 107 1e-21
UniRef50_Q4RHE1 Cluster: Chromosome 3 SCAF15050, whole genome sh... 107 1e-21
UniRef50_Q6SAX5 Cluster: Epidermal growth factor receptor; n=14;... 107 1e-21
UniRef50_Q17PG3 Cluster: Tyrosine-protein kinase drl; n=5; Endop... 107 1e-21
UniRef50_O12990 Cluster: Tyrosine-protein kinase Jak1; n=8; Eute... 107 1e-21
UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA... 107 2e-21
UniRef50_A7SI92 Cluster: Predicted protein; n=2; Nematostella ve... 107 2e-21
UniRef50_Q22489 Cluster: Putative uncharacterized protein; n=4; ... 106 2e-21
UniRef50_Q0IFX6 Cluster: Pdgf/vegf receptor; n=1; Aedes aegypti|... 106 2e-21
UniRef50_UPI000155CF4D Cluster: PREDICTED: similar to EPH recept... 106 3e-21
UniRef50_UPI0000E470E3 Cluster: PREDICTED: similar to Fer, parti... 106 3e-21
UniRef50_Q20933 Cluster: Putative uncharacterized protein; n=1; ... 106 3e-21
UniRef50_P10721 Cluster: Mast/stem cell growth factor receptor p... 106 3e-21
UniRef50_Q8JFR5 Cluster: Mast/stem cell growth factor receptor p... 106 3e-21
UniRef50_UPI00015B4A8D Cluster: PREDICTED: similar to receptor t... 105 4e-21
UniRef50_Q4SUM3 Cluster: Ephrin receptor; n=4; Tetraodon nigrovi... 105 4e-21
UniRef50_Q95YD4 Cluster: Protein kinase protein 32, isoform a; n... 105 4e-21
UniRef50_P36888 Cluster: FL cytokine receptor precursor; n=33; A... 105 4e-21
UniRef50_UPI0000DB7B8A Cluster: PREDICTED: similar to CG8789-PA,... 105 6e-21
UniRef50_Q4SFK0 Cluster: Chromosome 7 SCAF14601, whole genome sh... 105 6e-21
UniRef50_Q17833 Cluster: Putative uncharacterized protein old-1;... 105 6e-21
UniRef50_Q96HF4 Cluster: EPHA2 protein; n=3; Amniota|Rep: EPHA2 ... 105 6e-21
UniRef50_Q21038 Cluster: Putative uncharacterized protein ver-3;... 105 8e-21
UniRef50_UPI00015B55E4 Cluster: PREDICTED: similar to receptor-l... 104 1e-20
UniRef50_UPI0000D57516 Cluster: PREDICTED: similar to lemur tyro... 104 1e-20
UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC ... 104 1e-20
UniRef50_P34891 Cluster: Receptor-like tyrosine-protein kinase k... 104 1e-20
UniRef50_A4S4M0 Cluster: Predicted protein; n=1; Ostreococcus lu... 104 1e-20
UniRef50_Q60WJ5 Cluster: Putative uncharacterized protein CBG191... 104 1e-20
UniRef50_A2DXP4 Cluster: TKL family protein kinase; n=1; Trichom... 104 1e-20
UniRef50_Q2MHE4 Cluster: Serine/threonine-protein kinase HT1; n=... 104 1e-20
UniRef50_UPI000065E56D Cluster: EPHB1_HUMAN Isoform 3 of P54762 ... 103 2e-20
UniRef50_Q4RW26 Cluster: Chromosome 9 SCAF14991, whole genome sh... 103 2e-20
UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Cion... 103 2e-20
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-20
UniRef50_Q16LR4 Cluster: Tyrosine protein kinase; n=5; Coelomata... 103 2e-20
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 103 2e-20
UniRef50_P09619 Cluster: Beta-type platelet-derived growth facto... 103 2e-20
UniRef50_Q9U3B5 Cluster: Putative uncharacterized protein; n=3; ... 103 3e-20
UniRef50_UPI00015B6067 Cluster: PREDICTED: similar to tyrosine p... 102 4e-20
UniRef50_Q22765 Cluster: Putative uncharacterized protein; n=3; ... 102 4e-20
UniRef50_P16234 Cluster: Alpha-type platelet-derived growth fact... 102 4e-20
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 102 5e-20
UniRef50_Q5W6K6 Cluster: Kinase domain containing protein; n=2; ... 102 5e-20
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 102 5e-20
UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece... 102 5e-20
UniRef50_Q4JDD5 Cluster: Tyrosine-protein kinase receptor; n=5; ... 101 7e-20
UniRef50_Q18865 Cluster: Putative uncharacterized protein; n=5; ... 101 7e-20
UniRef50_Q8IQ00 Cluster: CG3277-PB, isoform B; n=3; Sophophora|R... 101 9e-20
UniRef50_P35916 Cluster: Vascular endothelial growth factor rece... 101 9e-20
UniRef50_A7RNB2 Cluster: Predicted protein; n=1; Nematostella ve... 101 1e-19
UniRef50_A2FY37 Cluster: TKL family protein kinase; n=1; Trichom... 101 1e-19
UniRef50_Q9U8U9 Cluster: PDGFR-like; n=1; Eptatretus burgeri|Rep... 100 2e-19
UniRef50_P35968 Cluster: Vascular endothelial growth factor rece... 100 2e-19
UniRef50_Q5GIT4 Cluster: Vascular endothelial growth factor rece... 100 2e-19
UniRef50_UPI0000F202EE Cluster: PREDICTED: similar to LCK2; n=2;... 100 2e-19
UniRef50_Q55GU0 Cluster: Protein kinase, TKL group; n=1; Dictyos... 100 2e-19
UniRef50_UPI0000F1F4DA Cluster: PREDICTED: hypothetical protein;... 99 3e-19
UniRef50_Q9M085 Cluster: Protein kinase-like protein; n=22; Magn... 99 3e-19
UniRef50_Q9FIL6 Cluster: Protein-tyrosine kinase; n=10; core eud... 99 3e-19
UniRef50_A2E1W1 Cluster: TKL family protein kinase; n=1; Trichom... 99 3e-19
UniRef50_A4SBG1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 100 4e-19
UniRef50_Q4H2M8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 100 4e-19
UniRef50_O02064 Cluster: Putative uncharacterized protein; n=1; ... 100 4e-19
UniRef50_UPI000065D8B4 Cluster: Basic fibroblast growth factor r... 99 5e-19
UniRef50_Q39886 Cluster: Protein kinase; n=7; Magnoliophyta|Rep:... 99 5e-19
UniRef50_Q7T6Y2 Cluster: Putative serine/threonine-protein kinas... 99 5e-19
UniRef50_UPI0001556099 Cluster: PREDICTED: similar to PTK7 prote... 99 7e-19
UniRef50_O17408 Cluster: Putative uncharacterized protein; n=1; ... 99 7e-19
UniRef50_Q55GE6 Cluster: WD40 repeat-containing protein; n=2; Di... 98 9e-19
UniRef50_Q54TA1 Cluster: E set domain-containing protein; n=1; D... 98 9e-19
UniRef50_Q21867 Cluster: Putative uncharacterized protein; n=2; ... 98 9e-19
UniRef50_A7RWY4 Cluster: Predicted protein; n=1; Nematostella ve... 98 9e-19
UniRef50_Q10925-2 Cluster: Isoform b of Q10925 ; n=2; Caenorhabd... 98 1e-18
UniRef50_Q4TFI7 Cluster: Chromosome undetermined SCAF4439, whole... 98 1e-18
UniRef50_Q4RXV8 Cluster: Chromosome 11 SCAF14979, whole genome s... 98 1e-18
>UniRef50_UPI0000D576E5 Cluster: PREDICTED: similar to CG33531-PA;
n=6; Endopterygota|Rep: PREDICTED: similar to CG33531-PA
- Tribolium castaneum
Length = 935
Score = 764 bits (1889), Expect = 0.0
Identities = 401/839 (47%), Positives = 534/839 (63%), Gaps = 52/839 (6%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
++ D GGAWCP Q TTE EW++IDL TVH+IT G+QGRFGNG G EYAEAY+LEY
Sbjct: 123 RVRTDRNGGAWCPLKQATTEPEEWIQIDLKTVHMITATGSQGRFGNGVGIEYAEAYMLEY 182
Query: 213 WRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVE 272
WRPKL KW+RY + G+E L GN NTYLE KN L PPIW SK+RF PYS H+RTVCMRVE
Sbjct: 183 WRPKLSKWIRYHNSKGEEVLPGNINTYLESKNTLVPPIWVSKIRFYPYSYHKRTVCMRVE 242
Query: 273 LYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQW-GEELRGGLGQLVDGQFGSDDIRE 331
LYGC ++ G+VSYSMP+GD+R + E D YDG W G+EL+ GLGQL+DG FG DD +
Sbjct: 243 LYGCRYTDGIVSYSMPQGDKRGSNWEFYDFGYDGHWDGDELKHGLGQLIDGIFGHDDFKT 302
Query: 332 ASKNSA--WVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISFS 388
+ A WVGW+ND+R P+ I FEFD+VREFSAVHI+CNN+F +DV +FS A + FS
Sbjct: 303 DFYDEAQTWVGWKNDTRQHKPIEIKFEFDRVREFSAVHIYCNNQFTKDVQIFSHAKVMFS 362
Query: 389 IGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDSD 448
+GG+ F+ EPI Y Y++D+IFENARNV+IKLHHR+G++V+++L FAA+W+LVSEI FDS
Sbjct: 363 VGGKRFKGEPITYEYMEDRIFENARNVTIKLHHRVGRFVKVQLHFAAKWLLVSEITFDSV 422
Query: 449 VAQGNYTPESMKPPVSKNKRKVISSKEVPISTANQ-EDPLYXXXXXXXXXXXXXXXXXXX 507
VA GN+T ES + + +++ I N+ +P Y
Sbjct: 423 VAHGNFTVESEPKAAPPTQGHELHEQKIEIPVPNKINEPAYLTIIVIGLAFIILLLGGVI 482
Query: 508 XXXXHRHKHRKCFASPLAKSAVSQKRAVESYSGCGTSMLPENKMILDCGLDVKSDEYQEP 567
HR ++RK F SP + + + + E ++ + ++Y+
Sbjct: 483 YLIIHRFRNRKFFRSPNSSNIGFPGDTLPHLQPESVLGMSEKGSSIEAYGVTEIEDYRRS 542
Query: 568 YQALKCAPY----FSYSTVLLEMKDFKDSNTALSDSSNYDYA--VPELSSA-PLLTKRMG 620
+ LK + + + E ++++ AL + Y Y+ V E+ A P K+
Sbjct: 543 HGTLKSSLRSTLPLPHPGHMSEGNEYQEPYQALKYAPYYSYSSVVMEMQDAMPNSIKKCP 602
Query: 621 ETLSQQATELVGEPMDTLPDLGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIE 680
V EP TLP LG+ +L P RS+ S+ S Q
Sbjct: 603 IQQIDAYDYAVPEP-GTLPLLGSDNTL-PINRSRMSSVSLKSQ----------------- 643
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
++ + +EG VY+AEADG+ E++ +++ RLVA+KFL +A KE+++F
Sbjct: 644 ----KMNARNSHSEGK--RVYIAEADGITEFSSSMSLGTRLVAIKFLGENAAEKEKKDFY 697
Query: 741 RDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR--------AAIPPTAA 791
RDVRILAAL P++ARVLG C + P+ VV+EYL+ GDLC FL+ A++P
Sbjct: 698 RDVRILAALEDPNIARVLGICSQEEPICVVMEYLDHGDLCQFLKTHVAADNNASLPYGVK 757
Query: 792 T-----LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
+ LL++ QIA+GM+YLESLNFVHRDLA RNCLIGKGYQIKI DFGT NE Y DY
Sbjct: 758 SLSFNCLLYMGAQIASGMRYLESLNFVHRDLATRNCLIGKGYQIKICDFGTYNELYINDY 817
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
YKVDG PLP+RW AWESV + +YTTKSDVWAFAVTL EI +LCRR PY+ L D EV++N
Sbjct: 818 YKVDGNTPLPIRWMAWESVYQTRYTTKSDVWAFAVTLWEILTLCRRPPYDSLPDPEVMEN 877
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNYATT 965
L+H+ DDG + + R P +D+Y+LMLECWRR +++RP+F EIH+FLQRK+L YA T
Sbjct: 878 LAHMHCDDGQYMYLPR-PTASKDIYDLMLECWRRKDVERPSFREIHIFLQRKNLGYAPT 935
Score = 209 bits (510), Expect = 3e-52
Identities = 90/137 (65%), Positives = 106/137 (77%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWL 69
+QCIAPLGME+G I D+D+TASS ++ GNV P +GR+ D GGAWCP Q TTE EW+
Sbjct: 88 SQCIAPLGMENGAIKDEDITASSSFDSGNVGPHHGRVRTDRNGGAWCPLKQATTEPEEWI 147
Query: 70 EIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTN 129
+IDL TVH+IT G+QGRFGNG G EYAEAY+LEYWRPKL KW+RY + G+E L GN N
Sbjct: 148 QIDLKTVHMITATGSQGRFGNGVGIEYAEAYMLEYWRPKLSKWIRYHNSKGEEVLPGNIN 207
Query: 130 TYLEKKNHLEPPIWASK 146
TYLE KN L PPIW SK
Sbjct: 208 TYLESKNTLVPPIWVSK 224
>UniRef50_Q8T0Z7 Cluster: Tyrosine kinase-like protein; n=1; Bombyx
mori|Rep: Tyrosine kinase-like protein - Bombyx mori
(Silk moth)
Length = 656
Score = 473 bits (1166), Expect = e-131
Identities = 229/249 (91%), Positives = 229/249 (91%), Gaps = 20/249 (8%)
Query: 737 EEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHI 796
EEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHI
Sbjct: 408 EEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHI 467
Query: 797 ATQIAAGMQYLESLNFVHRDLAAR----NCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 852
ATQIAAGMQYLESLNFVHRDLAAR NCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR
Sbjct: 468 ATQIAAGMQYLESLNFVHRDLAARYRLLNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 527
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCE---------- 902
VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCE
Sbjct: 528 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVRTRRLTDDA 587
Query: 903 ------VLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
VLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ
Sbjct: 588 PLKTFWVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 647
Query: 957 RKSLNYATT 965
RKSLNYATT
Sbjct: 648 RKSLNYATT 656
Score = 396 bits (975), Expect = e-108
Identities = 197/246 (80%), Positives = 205/246 (83%), Gaps = 25/246 (10%)
Query: 231 KLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWSVGVVSYSMPKG 290
KLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWSVGVVSYSMPKG
Sbjct: 164 KLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWSVGVVSYSMPKG 223
Query: 291 DRRSNGIELTDMIYDGQWGEELRGGLGQLVDGQFGSDDIREASKNSAWVGWRNDSRPDPP 350
DRRSNGIELTDMIYDGQWGEELRGGLGQLVDGQFGSDDIREASKNSAWVGWRNDSRPDPP
Sbjct: 224 DRRSNGIELTDMIYDGQWGEELRGGLGQLVDGQFGSDDIREASKNSAWVGWRNDSRPDPP 283
Query: 351 VIIFEFDKVREFSAVHIFCNNKFMRDVL----------VFSE--------AIISFSIGG- 391
VIIFEFDKVREFSAVHIFCNNKFMRDVL VF E A+ S+
Sbjct: 284 VIIFEFDKVREFSAVHIFCNNKFMRDVLVRIRKHYYRNVFVENTDHPTKHALFRCSLKQL 343
Query: 392 RHFQDEPIHY------TYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 445
HF+ + + + DKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF
Sbjct: 344 YHFRSAVVTFKTNLSTIHTSDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 403
Query: 446 DSDVAQ 451
DS + +
Sbjct: 404 DSGLEE 409
Score = 210 bits (514), Expect = 1e-52
Identities = 105/130 (80%), Positives = 105/130 (80%), Gaps = 25/130 (19%)
Query: 18 MESGLIADKDVTASSCYNDGNVAPQNGR-------------------------LNQDIKG 52
MESGLIADKDVTASSCYNDGNVAPQNGR LNQDIKG
Sbjct: 1 MESGLIADKDVTASSCYNDGNVAPQNGRYDNLLPGQLVLYKTELLTVALRFVRLNQDIKG 60
Query: 53 GAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKW 112
GAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKW
Sbjct: 61 GAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKW 120
Query: 113 VRYRSLDGQE 122
VRYRSLDGQE
Sbjct: 121 VRYRSLDGQE 130
Score = 176 bits (428), Expect = 3e-42
Identities = 77/79 (97%), Positives = 79/79 (100%)
Query: 152 LQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLE 211
++LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLE
Sbjct: 52 VRLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLE 111
Query: 212 YWRPKLGKWVRYRSLDGQE 230
YWRPKLGKWVRYRSLDGQE
Sbjct: 112 YWRPKLGKWVRYRSLDGQE 130
Score = 57.6 bits (133), Expect = 2e-06
Identities = 24/24 (100%), Positives = 24/24 (100%)
Query: 123 KLTGNTNTYLEKKNHLEPPIWASK 146
KLTGNTNTYLEKKNHLEPPIWASK
Sbjct: 164 KLTGNTNTYLEKKNHLEPPIWASK 187
>UniRef50_UPI00015B4909 Cluster: PREDICTED: similar to GA16357-PA,
partial; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GA16357-PA, partial - Nasonia vitripennis
Length = 826
Score = 462 bits (1139), Expect = e-128
Identities = 215/388 (55%), Positives = 281/388 (72%), Gaps = 13/388 (3%)
Query: 154 LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYW 213
L Q+ GGAWCP+ QITT+S+E++EIDLH VHVIT +GTQGRFGNGQG E+AEAY+LEYW
Sbjct: 1 LRQESSGGAWCPKPQITTKSSEYIEIDLHKVHVITASGTQGRFGNGQGAEFAEAYLLEYW 60
Query: 214 RPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVEL 273
RP LGKWVRY++ G+E + GN NTY+E K++L+PPIWASKVRF+PYS H+RTVCMRVEL
Sbjct: 61 RPALGKWVRYKNPSGEEVIQGNKNTYIEAKHYLDPPIWASKVRFLPYSYHQRTVCMRVEL 120
Query: 274 YGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGEELRGGLGQLVDGQFGSDDIREA- 332
YGC W+ G+VSYSMP+GD+R E D YDG W ++L GLGQL DG+ G D+ + +
Sbjct: 121 YGCPWNEGIVSYSMPQGDKRGTW-EFFDATYDGHWTDQLDRGLGQLTDGRIGPDNFKNSF 179
Query: 333 --SKNSAWVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISFSI 389
SK+ WVGWRND+R P+ I FEFD VREFSAVHI+CNN+F ++V +FSE I FSI
Sbjct: 180 HDSKDQGWVGWRNDTRQGHPLEIKFEFDHVREFSAVHIYCNNQFNKEVQLFSEVNILFSI 239
Query: 390 GGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDSDV 449
GG+++ +PI Y +D+IF+ +RN++IKLHHRIGK+V++ FAARWI++SEI FDSD+
Sbjct: 240 GGKYYTGDPIVYDTPEDRIFDYSRNITIKLHHRIGKFVKLRFGFAARWIMISEITFDSDI 299
Query: 450 AQGNYTPE---SMKPPVSKNKRKVISSK----EVPISTANQEDPLYXXXXXXXXXXXXXX 502
A GN+TPE + + P +++ + + EVP+STA Q+DP Y
Sbjct: 300 AHGNFTPELPPTTEAPRIRDRGSLRETPRHHVEVPVSTAKQDDPTYMAVIIGVLTAVILL 359
Query: 503 XXXXXXXXXHRHKHRKCFASPL-AKSAV 529
RH+ RK FASPL +KSA+
Sbjct: 360 LAVAIFLIVSRHRQRKNFASPLSSKSAI 387
Score = 169 bits (412), Expect = 2e-40
Identities = 70/101 (69%), Positives = 87/101 (86%)
Query: 46 LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYW 105
L Q+ GGAWCP+ QITT+S+E++EIDLH VHVIT +GTQGRFGNGQG E+AEAY+LEYW
Sbjct: 1 LRQESSGGAWCPKPQITTKSSEYIEIDLHKVHVITASGTQGRFGNGQGAEFAEAYLLEYW 60
Query: 106 RPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASK 146
RP LGKWVRY++ G+E + GN NTY+E K++L+PPIWASK
Sbjct: 61 RPALGKWVRYKNPSGEEVIQGNKNTYIEAKHYLDPPIWASK 101
>UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to
prenylcysteine oxidase 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to prenylcysteine oxidase 1 - Nasonia
vitripennis
Length = 807
Score = 359 bits (884), Expect = 2e-97
Identities = 188/329 (57%), Positives = 230/329 (69%), Gaps = 38/329 (11%)
Query: 658 RSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITS 717
+SP+QQE+L LK+RLE T+V FPRHRLRM+SKLAEGAFG+VY+AEA+G+PEY T
Sbjct: 18 QSPTQQEVLSALKKRLEQTSVPLFPRHRLRMLSKLAEGAFGSVYIAEAEGIPEYGTTTTL 77
Query: 718 EKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELG 776
KRLVAVKFL +A KE+ +F+RDVRILAAL ++ARVLGAC R P VV+EYLE G
Sbjct: 78 GKRLVAVKFLLPEANEKEKLDFQRDVRILAALEDRNIARVLGACCREEPFCVVMEYLEHG 137
Query: 777 DLCAFLRAAIPPTAA-------------TLLHIATQIAAGMQYLESLNFVHRDLAARNCL 823
DLC FL+ + A L+++A QIA+GM+YLE+LNFVHRDLA RNCL
Sbjct: 138 DLCQFLKTHVTAEDAHSMPIGVKTLSFNCLIYMAAQIASGMRYLENLNFVHRDLATRNCL 197
Query: 824 IGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTL 883
+GK Y IKISDFGTDNE Y CDYYKVDG +PLP+RW AWES++ GKYTTKSDVW+FAV L
Sbjct: 198 VGKAYHIKISDFGTDNELYACDYYKVDGGIPLPVRWMAWESLVLGKYTTKSDVWSFAVML 257
Query: 884 HEIYSLCRRRPYEHLTDCEVLDNLSHL------------------QADDGM------FEC 919
EI +L RR PYEHL+D EV+ L L + DD + FE
Sbjct: 258 WEILNLGRRVPYEHLSDQEVVRCLRRLCCDCSDSNEASQLKSSEEEEDDELEKIGLSFEH 317
Query: 920 VDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ + +D+Y+LMLECWRRDE +RPTF
Sbjct: 318 LPKPSASSKDIYDLMLECWRRDEAERPTF 346
>UniRef50_UPI0000519EF1 Cluster: PREDICTED: similar to CG31640-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG31640-PA - Apis mellifera
Length = 882
Score = 356 bits (875), Expect = 2e-96
Identities = 168/342 (49%), Positives = 230/342 (67%), Gaps = 13/342 (3%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
+L QD GGAWCP++ +T E E+LE++LH+ ++T TQGRFGNG G EY E Y +EY
Sbjct: 27 RLRQDKGGGAWCPKNMVTKEGKEYLEVNLHSPRILTSTRTQGRFGNGHGVEYTEEYFVEY 86
Query: 213 WRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVE 272
WRP KWVR+R+ G E L GN N Y EK+ +P I A+KVRFIPY+SH R VC+RVE
Sbjct: 87 WRPGFNKWVRWRNRRGMELLAGNNNPYSEKEQLFDPAIVATKVRFIPYTSHMRMVCIRVE 146
Query: 273 LYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSDDIRE 331
LYGC W+ G+VSYSMP+G +R + ++L+D YDG + G L GGLGQLVDGQ G D+ R
Sbjct: 147 LYGCPWTEGLVSYSMPQGIKRGSEVDLSDRTYDGREEGGYLSGGLGQLVDGQKGPDNFRL 206
Query: 332 ASKNS---AWVGWRNDSRP---DPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAII 385
S N WVGWRND+ P I FEFD R F+A+H+ NN F +DV VFS A +
Sbjct: 207 DSGNGKGYEWVGWRNDTPSMLGRPVEITFEFDYSRNFTAIHLHMNNYFTKDVQVFSYAKV 266
Query: 386 SFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 445
GG F EP+H++Y+ D + E AR+V+IKLH R G++++++L FAARWI++SE++F
Sbjct: 267 YLGAGGNQFNGEPVHFSYIPDLVLEQARDVTIKLHSRAGRFLKLQLYFAARWIMLSEVIF 326
Query: 446 DSDVAQGNYTPESMKPPVSKNKRKVISSKEVPISTANQEDPL 487
+S +++ N T + ++NK ++S+ +P N E PL
Sbjct: 327 ESVISEWNNTDDE----EARNKSGIVSATGIPYQ--NNEGPL 362
Score = 274 bits (672), Expect = 7e-72
Identities = 139/349 (39%), Positives = 216/349 (61%), Gaps = 14/349 (4%)
Query: 627 ATELVGEPMDTLPDLGTRRSLNP-SVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHR 685
+TE+ + LP T + P S ++ S S S +++L + + + +++FPR +
Sbjct: 526 STEICKNSLPPLPPSPTPSTPPPMSAKASSSMTSYSPEDMLTEEEDEVAEC-ILDFPREK 584
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAI-TSEKRLVAVKFLCHDATLKEREEFERDVR 744
L ++ L G FG V++ E D P Y+ + LV VK L ++ R EF+ + +
Sbjct: 585 LNIVENLGCGYFGDVHICEVDRFPGYDEVFRNTASDLVIVKSLRPGSSDALRIEFQEEAK 644
Query: 745 ILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPPTAA----------TL 793
LA L+ ++AR+LGA P+ +VLE E GDL +L+ I T+ TL
Sbjct: 645 KLARLADRNVARLLGASLGDDPMCIVLENGEYGDLNQYLQRHIAETSTVHTAKTLSFGTL 704
Query: 794 LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRV 853
+++ATQIA+GM++LE ++ VHRDLA RNCL+ +GY +K+ D G+ AY DY++V+GR
Sbjct: 705 IYMATQIASGMKHLEEMDLVHRDLATRNCLVSRGYTVKVCDLGSGRNAYAADYFRVEGRP 764
Query: 854 PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQAD 913
PLP+RW AWE++L G++T+KSDVW+FAVTL EI + R +P+E L D +++N ++ +
Sbjct: 765 PLPIRWMAWEAMLMGRHTSKSDVWSFAVTLWEILTFAREQPFEELPDHRIVENATYFYQE 824
Query: 914 DGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNY 962
D + CP+D+YELM ECW R+++DRP+F EIH+FLQRK+L Y
Sbjct: 825 DDRRIILPLPKNCPKDIYELMRECWHRNDVDRPSFREIHMFLQRKNLGY 873
Score = 150 bits (363), Expect = 2e-34
Identities = 66/129 (51%), Positives = 89/129 (68%), Gaps = 1/129 (0%)
Query: 18 MESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEIDLHTVH 77
ME+G I D+D++ASS Y D ++ P++ RL QD GGAWCP++ +T E E+LE++LH+
Sbjct: 1 MENGEIPDEDISASSMY-DPSLGPKHARLRQDKGGGAWCPKNMVTKEGKEYLEVNLHSPR 59
Query: 78 VITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNH 137
++T TQGRFGNG G EY E Y +EYWRP KWVR+R+ G E L GN N Y EK+
Sbjct: 60 ILTSTRTQGRFGNGHGVEYTEEYFVEYWRPGFNKWVRWRNRRGMELLAGNNNPYSEKEQL 119
Query: 138 LEPPIWASK 146
+P I A+K
Sbjct: 120 FDPAIVATK 128
>UniRef50_Q59DZ7 Cluster: CG33531-PA; n=6; Sophophora|Rep:
CG33531-PA - Drosophila melanogaster (Fruit fly)
Length = 1064
Score = 355 bits (874), Expect = 2e-96
Identities = 165/304 (54%), Positives = 215/304 (70%), Gaps = 6/304 (1%)
Query: 160 GGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGK 219
GGAWCP+ ++ TE+L++DL VH+++ TQGRFG GQGQEY EAYV+EYWRP L K
Sbjct: 146 GGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKK 205
Query: 220 WVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWS 279
W+R+RSL G+E L GN NTY E +N L+P ++ASKVR PYS + RTVC+R E+ GC W
Sbjct: 206 WIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWE 265
Query: 280 VGVVSYSMPKGDRRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSD----DIREASK 334
G+VSYS+PKG +R I+L+D YDG + G+ GLGQLVDGQ G D DI K
Sbjct: 266 EGIVSYSIPKGMQRGMDIDLSDKTYDGYEEGDHYVNGLGQLVDGQRGKDNFRADINGLGK 325
Query: 335 NSAWVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISFSIGGRH 393
W+GWRND+ PV IIFEF+ VR SAV I NN F +DV VF A + FSIGGRH
Sbjct: 326 GYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFVHAKVFFSIGGRH 385
Query: 394 FQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDSDVAQGN 453
F EP+ ++Y+ D + ++AR+V+IKLHHR+G++V++ L FAARW+++SEI F S GN
Sbjct: 386 FSGEPVQFSYMPDLVLDHARDVTIKLHHRLGRYVQLHLYFAARWMMISEITFISAPVVGN 445
Query: 454 YTPE 457
+T E
Sbjct: 446 FTDE 449
Score = 256 bits (626), Expect = 3e-66
Identities = 137/317 (43%), Positives = 195/317 (61%), Gaps = 24/317 (7%)
Query: 668 DLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEAD---GVPEYNGAITSEKRLVAV 724
D+ V EFPR L ++ KL G FG +++ E + + E++ ++ LVAV
Sbjct: 741 DINEERANCQVQEFPRQSLVIVEKLGSGVFGELHLCETNVLNDLTEFDSHCSAT--LVAV 798
Query: 725 KFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLE-LGDLCAFL 782
L A R+EF + LA LS P++AR++GAC R P+ +V +Y LGDL FL
Sbjct: 799 ATLRPGANDHLRKEFRSKAKQLAQLSDPNVARLVGACLRDEPICIVQDYSHCLGDLNQFL 858
Query: 783 RAAIPPTAAT----------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKI 832
+ + T+ L++IATQIA+GM++LE +NFVHRDLA R+C+IG +K+
Sbjct: 859 QEHVAETSGLMAKKSLSFGCLVYIATQIASGMKHLEQMNFVHRDLATRSCIIGPELCVKV 918
Query: 833 SDFGT--DNEAYTCDYYKVDGRV-----PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHE 885
GT + AY DY +++G P+P+RW AWESVL GK+TTKSDVW+FAV L E
Sbjct: 919 CSIGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMAWESVLLGKFTTKSDVWSFAVALWE 978
Query: 886 IYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDR 945
I + R +PYEHL+D V++N+ + D M E + P CPR++Y+LM ECW+RDE R
Sbjct: 979 ILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLPMPPNCPREIYDLMCECWQRDESSR 1038
Query: 946 PTFGEIHLFLQRKSLNY 962
P+F EIHL+LQRK+L +
Sbjct: 1039 PSFREIHLYLQRKNLGF 1055
Score = 174 bits (423), Expect = 1e-41
Identities = 84/168 (50%), Positives = 109/168 (64%), Gaps = 7/168 (4%)
Query: 3 LSTSMTDAQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQIT 62
L M C LGMESG IAD +TASS ++ GNV PQ+ R + GGAWCP+ ++
Sbjct: 97 LLAEMPIGTCKQALGMESGAIADFQITASSAHDMGNVGPQHARAANNNNGGAWCPKHMVS 156
Query: 63 TESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQE 122
TE+L++DL VH+++ TQGRFG GQGQEY EAYV+EYWRP L KW+R+RSL G+E
Sbjct: 157 RGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKE 216
Query: 123 KLTGNTNTYLEKKNHLEPPIWASK-------DYQQGLQLNQDIKGGAW 163
L GN NTY E +N L+P ++ASK Y + + L +I G AW
Sbjct: 217 VLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAW 264
>UniRef50_Q17HL3 Cluster: Discoidin domain receptor; n=3;
Culicidae|Rep: Discoidin domain receptor - Aedes aegypti
(Yellowfever mosquito)
Length = 901
Score = 349 bits (859), Expect = 2e-94
Identities = 163/312 (52%), Positives = 218/312 (69%), Gaps = 8/312 (2%)
Query: 154 LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYW 213
L D GGAWCP+ ++ E+L+IDL +HV+T TQGRFG GQG+EY EAYVLEYW
Sbjct: 11 LKVDNNGGAWCPKHMVSRNLNEYLQIDLKRMHVVTAIKTQGRFGKGQGREYTEAYVLEYW 70
Query: 214 RPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVEL 273
RP KW R+++ E L+GNTNTY E +N L+P I+ASK+R PYS + RTVC+R E+
Sbjct: 71 RPGFSKWKRWKNTRDNEILSGNTNTYSEVENLLQPIIFASKIRIYPYSQYDRTVCLRAEI 130
Query: 274 YGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSD----D 328
GC W G++SYS+PKG R ++L+D IYDG + G+ L GGLGQLVDGQ G+D D
Sbjct: 131 IGCEWDEGLLSYSIPKGVIRGMEVDLSDRIYDGEEEGDRLVGGLGQLVDGQKGADNFRTD 190
Query: 329 IREASKNSAWVGWRNDS---RPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAII 385
I K WVGWRNDS P ++FEFD VR F+A+ + NN F +DV VF +A +
Sbjct: 191 IHGFGKGYDWVGWRNDSLGWAGKPVEMVFEFDTVRNFTAMVLHTNNMFSKDVQVFLQAKV 250
Query: 386 SFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 445
FSIGG+HF +EP+H++Y+ D I E+AR+V+IKLHHRIG+++++ L F+ RWI++SEI F
Sbjct: 251 YFSIGGQHFSNEPVHFSYMPDAIMESARDVTIKLHHRIGRFIQVHLYFSMRWIMLSEISF 310
Query: 446 DSDVAQGNYTPE 457
S GN++ E
Sbjct: 311 ISSPVIGNFSDE 322
Score = 243 bits (594), Expect = 2e-62
Identities = 135/336 (40%), Positives = 198/336 (58%), Gaps = 28/336 (8%)
Query: 649 PSVRSKQSTRSPSQQEILLDLKRRL--ETTNVIEFPRHRLRMISKLAEGAFGTVYVAEAD 706
PS + + + Q DL + + + E+PR +L ++ KL G FG +++ E
Sbjct: 571 PSNNQQSNQQQQQQLNAYSDLDHGVSDDDLQLSEYPRDKLVIVEKLGCGVFGELHLCETK 630
Query: 707 GVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPP 765
G LVAV L A+ ++EF + L+ L+ P++A+++GAC + P
Sbjct: 631 GY---------SSNLVAVSTLRPGASEHVKKEFRAKAKQLSRLNDPNVAKLIGACLKDEP 681
Query: 766 LAVVLEYLELGDLCAFLRAAIPPTAAT----------LLHIATQIAAGMQYLESLNFVHR 815
+ +VL+Y DL FL+ T L++IATQIA+GM+YLE +N VHR
Sbjct: 682 ICIVLDYKFGTDLNQFLQEHTAETGTLVQHNSLSYGCLIYIATQIASGMKYLEQMNVVHR 741
Query: 816 DLAARNCLIGKGYQIKISDFGT--DNEAYTCDYYKVDGR----VPLPLRWAAWESVLRGK 869
DLAAR+CL+G +IKI GT + AY DY ++G P+P+RW AWESVL GK
Sbjct: 742 DLAARSCLVGPQLEIKICTLGTVINRIAYPADYCHLEGAGRQSQPMPIRWMAWESVLMGK 801
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRD 929
+T+KSDVW+FAVTL EI + R +P+E+L+D +V++N+ H+ D+ + GCPR+
Sbjct: 802 FTSKSDVWSFAVTLWEILTFAREQPFENLSDEKVIENIGHMYQDNKKHIQLPIPVGCPRE 861
Query: 930 LYELMLECWRRDELDRPTFGEIHLFLQRKSLNYATT 965
+Y+LM ECW+R+E RP F EIHLFLQRK+L Y T
Sbjct: 862 IYDLMCECWQRNENSRPNFREIHLFLQRKNLGYKPT 897
Score = 131 bits (316), Expect = 1e-28
Identities = 60/109 (55%), Positives = 75/109 (68%), Gaps = 1/109 (0%)
Query: 39 VAPQNGR-LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYA 97
V PQ R L D GGAWCP+ ++ E+L+IDL +HV+T TQGRFG GQG+EY
Sbjct: 3 VTPQKERVLKVDNNGGAWCPKHMVSRNLNEYLQIDLKRMHVVTAIKTQGRFGKGQGREYT 62
Query: 98 EAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASK 146
EAYVLEYWRP KW R+++ E L+GNTNTY E +N L+P I+ASK
Sbjct: 63 EAYVLEYWRPGFSKWKRWKNTRDNEILSGNTNTYSEVENLLQPIIFASK 111
>UniRef50_Q9VMG2 Cluster: CG31640-PA; n=2; Drosophila
melanogaster|Rep: CG31640-PA - Drosophila melanogaster
(Fruit fly)
Length = 808
Score = 345 bits (849), Expect = 3e-93
Identities = 162/314 (51%), Positives = 213/314 (67%), Gaps = 8/314 (2%)
Query: 152 LQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLE 211
L L D GGAWCP+ ++ E+L++DL HVIT TQGR+G GQGQEY EAYVLE
Sbjct: 15 LLLKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLE 74
Query: 212 YWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRV 271
YWRP KW R++++ G+E L GN NTY E +N L+P I+ASK+R PY + RTVC+R
Sbjct: 75 YWRPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRA 134
Query: 272 ELYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSD--- 327
E+ GC W G+VSYS+PKG +R ++L+D YDG + G+ GLGQLVDGQ G D
Sbjct: 135 EIVGCPWEEGIVSYSIPKGVQRGMEVDLSDKTYDGNEQGDRYVDGLGQLVDGQKGKDNFR 194
Query: 328 -DIREASKNSAWVGWRNDS---RPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEA 383
DI K W+GWRND+ P I+FEFD VR FSA+ + NN F +DV VF A
Sbjct: 195 TDIHGFGKGYEWIGWRNDTPGLLGKPVEIVFEFDTVRNFSAIVLHTNNMFTKDVQVFVHA 254
Query: 384 IISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEI 443
+ FSIGGR+F EP+ ++Y+ D I ++AR+V+IKLHHR+GK+++I L FA +WI++SEI
Sbjct: 255 KVFFSIGGRYFSGEPVQFSYMPDTIMDHARDVTIKLHHRVGKYLKINLYFAVKWIMLSEI 314
Query: 444 VFDSDVAQGNYTPE 457
F S A GN+T E
Sbjct: 315 SFISVPAMGNFTDE 328
Score = 129 bits (311), Expect = 4e-28
Identities = 61/125 (48%), Positives = 79/125 (63%), Gaps = 7/125 (5%)
Query: 46 LNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYW 105
L D GGAWCP+ ++ E+L++DL HVIT TQGR+G GQGQEY EAYVLEYW
Sbjct: 17 LKTDNDGGAWCPKHMVSNALKEYLQVDLLQTHVITAIRTQGRYGKGQGQEYTEAYVLEYW 76
Query: 106 RPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASK-------DYQQGLQLNQDI 158
RP KW R++++ G+E L GN NTY E +N L+P I+ASK Y + + L +I
Sbjct: 77 RPGFDKWQRWKNIQGKEILPGNINTYSEVENALQPIIFASKIRIYPYGQYDRTVCLRAEI 136
Query: 159 KGGAW 163
G W
Sbjct: 137 VGCPW 141
>UniRef50_UPI00015B629F Cluster: PREDICTED: similar to CG33531-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG33531-PA - Nasonia vitripennis
Length = 834
Score = 322 bits (792), Expect = 2e-86
Identities = 157/344 (45%), Positives = 219/344 (63%), Gaps = 12/344 (3%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
+L+ + GGAWCP+ +T E E+LE++L + VIT TQGR+GNG G EY E Y +EY
Sbjct: 62 RLHNNNGGGAWCPKDMVTKEPKEYLEVNLRSPRVITSTRTQGRYGNGHGVEYTEEYYIEY 121
Query: 213 WRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVE 272
WRP +W R+++ G + L GN N EK+ +PP+ A+K+RFIPY+SH R +CMRVE
Sbjct: 122 WRPGFSEWRRWKNRRGMDLLVGNDNPKTEKEQVFDPPVVATKIRFIPYTSHIRIICMRVE 181
Query: 273 LYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSD---- 327
LYGC W+ G+ SYSMP+G R + ++LTD YDG + L GGLGQL DGQ G+D
Sbjct: 182 LYGCPWTEGLASYSMPQGVLRGSELDLTDRTYDGVEEDGLLSGGLGQLADGQKGADNFFR 241
Query: 328 -DIREASKNSAWVGWRNDS---RPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEA 383
D+ K WVGWRND+ P I FEFD R F+A+H+ +N F +DV VFS A
Sbjct: 242 LDVNGNGKGYEWVGWRNDTPNMLGQPVEITFEFDYGRNFTAMHLHTSNFFTKDVQVFSHA 301
Query: 384 IISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEI 443
+ FS F EP+H++Y+ D +FE AR+V+IKLH R G++++++L FAA WI++SE+
Sbjct: 302 KVYFSSTSSLFNGEPVHFSYIPDLMFEQARDVTIKLHSRAGRFIKLQLYFAAHWIMLSEV 361
Query: 444 VFDSDVAQGNYTPESMKPPVSKNKRKVISSKEVPISTANQEDPL 487
F+S V++ N + E + +KN V + I N E PL
Sbjct: 362 SFESVVSEWNNSTEEEEVAKTKN---VTTVPTTGIPFQNNEGPL 402
Score = 265 bits (650), Expect = 3e-69
Identities = 128/297 (43%), Positives = 187/297 (62%), Gaps = 12/297 (4%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAI-TSEKRLVAVKFLCHDATLKER 736
+ +FPR RL + L G FG +++ E D P Y + LV VK L ++ R
Sbjct: 531 IFDFPRERLNIAENLGSGYFGDIHICEVDRFPGYEEVFRNTSSDLVVVKSLRPGSSEVLR 590
Query: 737 EEFERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPPTAA---- 791
EF ++ + LA L+ ++AR+LGA P+ +VLE E GDL +L++ + T
Sbjct: 591 IEFRQEAKRLARLNDRNVARLLGASLDDDPMCIVLENGEYGDLNQYLQSHVAETTTVQTA 650
Query: 792 ------TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD 845
TL+++ATQIA+GM+YLE ++FVHRDLA RNCL+ +G +K+SD G AY+ D
Sbjct: 651 KTLSFGTLIYMATQIASGMKYLEEMDFVHRDLATRNCLVSQGNHVKVSDLGPGRSAYSAD 710
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
Y+K++GR +P+RW AWES+L G YT+KSDVWAFAVT EI + R +P+E L D +++
Sbjct: 711 YFKIEGRPAMPIRWMAWESMLVGNYTSKSDVWAFAVTFWEILTFAREQPFEELPDHRIVE 770
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNY 962
N ++ +D + CP+++Y+LM ECW+R++ DRP F EIHLFLQRK+L Y
Sbjct: 771 NATYFYQEDDRRLILPLPKNCPKEMYDLMRECWQRNDSDRPNFREIHLFLQRKNLGY 827
Score = 148 bits (359), Expect = 6e-34
Identities = 69/149 (46%), Positives = 98/149 (65%), Gaps = 4/149 (2%)
Query: 1 MALSTSMTD---AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCP 57
++LSTS+ QC A LGM+SG I D+D+TASS Y D ++ P++ RL+ + GGAWCP
Sbjct: 16 LSLSTSLQALDLGQCTAALGMQSGEIPDEDITASSFY-DPSLGPKHARLHNNNGGGAWCP 74
Query: 58 RSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRS 117
+ +T E E+LE++L + VIT TQGR+GNG G EY E Y +EYWRP +W R+++
Sbjct: 75 KDMVTKEPKEYLEVNLRSPRVITSTRTQGRYGNGHGVEYTEEYYIEYWRPGFSEWRRWKN 134
Query: 118 LDGQEKLTGNTNTYLEKKNHLEPPIWASK 146
G + L GN N EK+ +PP+ A+K
Sbjct: 135 RRGMDLLVGNDNPKTEKEQVFDPPVVATK 163
>UniRef50_UPI0000D576E4 Cluster: PREDICTED: similar to CG33531-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG33531-PA - Tribolium castaneum
Length = 904
Score = 316 bits (777), Expect = 1e-84
Identities = 151/326 (46%), Positives = 217/326 (66%), Gaps = 9/326 (2%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
+L + GG WCP+ Q+ E+L++DL VHV+TG TQGR+ G+GQEYAE Y +EY
Sbjct: 60 RLRVEKAGGGWCPKQQVERGIREYLQVDLGEVHVVTGVQTQGRYDRGRGQEYAEEYTVEY 119
Query: 213 WRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVE 272
WRP L +W Y+ D ++ L GN++T + L PP++ASKVR +PYS HRRTVC+R+E
Sbjct: 120 WRPGLNEWKEYKRWDNKQILRGNSDTASVESQRLMPPVFASKVRILPYSVHRRTVCLRIE 179
Query: 273 LYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGE-ELRGGLGQLVDGQFGSDDIR- 330
L GC + G++SYS+P+G S G L D YDG + L GGLG+LVDG+FG+D+ R
Sbjct: 180 LLGCPYEGGIISYSIPEGSEPSQG--LYDSSYDGTRNDGTLEGGLGRLVDGEFGADNFRL 237
Query: 331 --EASKNSAWVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISF 387
K + W+ W+ND+ + V + FEFD++R FS V++F NN F R+V VFS+A + F
Sbjct: 238 DIGYGKGNGWIAWKNDTSANGYVELTFEFDQIRNFSEVYLFTNNFFSRNVQVFSKAKVMF 297
Query: 388 SIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDS 447
SIGGR + + Y+Y+ D++ ENARNVSI LH R+ +++++ L FA RW+++SE+ FDS
Sbjct: 298 SIGGRFYNGPTLSYSYMPDRVLENARNVSINLHQRLARFIKLRLFFADRWMMLSEVAFDS 357
Query: 448 DVAQGNYTPESMKPPVSKNKRKVISS 473
N + E +S+N+ VISS
Sbjct: 358 VPVAFNISEEETL-DLSENE-LVISS 381
Score = 196 bits (477), Expect = 3e-48
Identities = 109/305 (35%), Positives = 172/305 (56%), Gaps = 26/305 (8%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKERE 737
++ PR+ LR + K+ G + + E +G+ + I RLVAV+ + +
Sbjct: 608 LVPIPRYSLRPLEKVGSCHAGEITLCETEGLEDI---IPGVCRLVAVRTPSPERAKSDAA 664
Query: 738 ----EFERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAI------ 786
E R+VR LA+LS P++ +VLG C + P V+EY E+GDL +L+ +
Sbjct: 665 TGSMESLREVRFLASLSDPNICKVLGVCTAEQPPWTVIEYGEMGDLAQYLQFLVNRNGTV 724
Query: 787 ------PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
P + L+++A+Q+A+GM+YLES + VH+DLAAR + +KI+D
Sbjct: 725 RSSADQPVSVDNLIYMASQVASGMKYLESKHVVHKDLAARR------FVVKIADVAMCKP 778
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y DY ++ GR P P+RW WES+L +Y+ S VWAFAVTL EI S RP+ +L++
Sbjct: 779 QYRKDYAEIGGRPPAPIRWLPWESILLDRYSCSSSVWAFAVTLWEILSFACERPFSNLSN 838
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSL 960
+V+ N H+ + + + P C ++YE+M +CW+RD+ +RPTF EI LFL+ +
Sbjct: 839 EKVIQNAEHMYYGGELQVLLSKPPICSTEIYEMMCQCWKRDDTERPTFKEICLFLKHHNK 898
Query: 961 NYATT 965
+Y T
Sbjct: 899 DYTPT 903
Score = 152 bits (369), Expect = 4e-35
Identities = 72/149 (48%), Positives = 97/149 (65%), Gaps = 5/149 (3%)
Query: 2 ALSTSMTDA----QCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCP 57
AL+ ++ DA C PLGMESG I D+ +TASS Y NV P+NGRL + GG WCP
Sbjct: 14 ALTLNLCDAFETRSCNEPLGMESGTIPDEAITASSSYVP-NVGPRNGRLRVEKAGGGWCP 72
Query: 58 RSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRS 117
+ Q+ E+L++DL VHV+TG TQGR+ G+GQEYAE Y +EYWRP L +W Y+
Sbjct: 73 KQQVERGIREYLQVDLGEVHVVTGVQTQGRYDRGRGQEYAEEYTVEYWRPGLNEWKEYKR 132
Query: 118 LDGQEKLTGNTNTYLEKKNHLEPPIWASK 146
D ++ L GN++T + L PP++ASK
Sbjct: 133 WDNKQILRGNSDTASVESQRLMPPVFASK 161
>UniRef50_UPI0000DB7238 Cluster: PREDICTED: similar to Discoidin
domain receptor CG33531-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Discoidin domain receptor
CG33531-PA - Apis mellifera
Length = 898
Score = 293 bits (718), Expect = 2e-77
Identities = 146/314 (46%), Positives = 206/314 (65%), Gaps = 18/314 (5%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
+L ++ GGAWCP+SQI EWL++DL HVITG +QGR+ +G+GQEY E Y LEY
Sbjct: 58 RLRKETAGGAWCPKSQIERGIREWLQVDLPGPHVITGVQSQGRYDHGRGQEYVEEYTLEY 117
Query: 213 WRPKLGKWVRYRSLD---------GQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSH 263
RP +W RY+ D G E L GNT+T + L P I+A+++R +P+S H
Sbjct: 118 RRPGFAEWRRYKRWDNKEVRGRNSGAEVLAGNTDTSTVVSHRLVPAIFATQIRILPHSEH 177
Query: 264 RRTVCMRVELYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGEEL-RGGLGQLVDG 322
RRTVC+R+EL GC + GVVSY++P+ S IEL+D+ YDG+ + L GLG+L+DG
Sbjct: 178 RRTVCLRIELRGCKDTGGVVSYTIPE----SPTIELSDISYDGKRQDNLLTDGLGRLIDG 233
Query: 323 QFGSDDIR---EASKNSAWVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVL 378
+ G+D+ R + + WV W D+ D V ++FEF+ + F AVHI+ NN F RDV
Sbjct: 234 EVGADNYRLDMGDGRGTGWVAWMRDTFVDDYVELVFEFEVIWIFEAVHIYTNNYFSRDVQ 293
Query: 379 VFSEAIISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWI 438
VFS+A + FS+ G +++EP+ Y+Y+ D + ENARNVSI LH R G++++I L FAARWI
Sbjct: 294 VFSKADVWFSVDGATYEEEPLSYSYIPDIVLENARNVSIGLHEREGRFLKIHLYFAARWI 353
Query: 439 LVSEIVFDSDVAQG 452
++SE+VFD G
Sbjct: 354 MISEVVFDGITVAG 367
Score = 217 bits (530), Expect = 1e-54
Identities = 117/318 (36%), Positives = 178/318 (55%), Gaps = 32/318 (10%)
Query: 671 RRLETTNVIEFPRHRLRMISKLAEGAFGT----------VYVAEADGVPEYNGAITSEKR 720
+ +E TN+ PR LR KL G V EA G+ + A+ R
Sbjct: 583 KEIEPTNI---PRQCLRTTEKLGSRNIGEQELSFNFCPQAIVCEAVGLED---AVADAPR 636
Query: 721 LVAVKFLCHDATLKEREEFE--RDVRILAALSSPHLARVLGACRSPPLA-VVLEYLELGD 777
LV + ++ + R+VR L++LS P++AR+LG C P+ ++EY ELGD
Sbjct: 637 LVVARVPACTGDIRGGSAADQIREVRFLSSLSDPNVARILGVCAVEPVPWTIIEYTELGD 696
Query: 778 LCAFLRAAIPPTA-------------ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLI 824
L +L+ ++P T + L+++ QIA+GM++LES N VH+DLAARNCL+
Sbjct: 697 LAHYLQYSVPLTGTLRPSCNLKALSQSCLMYMGAQIASGMRFLESKNLVHKDLAARNCLV 756
Query: 825 GKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLH 884
G+ Y +K++D ++ Y DY + GR P P+RW WES+L +YT S VW+FAVTL
Sbjct: 757 GRSYTVKVTDIAMCSDLYKKDYSDIGGRPPAPIRWLPWESILLDRYTCSSSVWSFAVTLW 816
Query: 885 EIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELD 944
E+ SL R +P++HLT+ +V+ N H+ + + + CP ++Y +M CWRRDE
Sbjct: 817 EVMSLAREKPFQHLTNDQVIQNAEHMYYGAELQIYLPKPTMCPEEVYRMMCSCWRRDETS 876
Query: 945 RPTFGEIHLFLQRKSLNY 962
RPTF +I+ FL+ +Y
Sbjct: 877 RPTFKDIYTFLKNIISDY 894
Score = 134 bits (324), Expect = 1e-29
Identities = 70/144 (48%), Positives = 88/144 (61%), Gaps = 10/144 (6%)
Query: 12 CIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEI 71
C LGMESG I D +TASS Y NV P+NGRL ++ GGAWCP+SQI EWL++
Sbjct: 26 CNQSLGMESGDIPDSAITASSSYVT-NVGPRNGRLRKETAGGAWCPKSQIERGIREWLQV 84
Query: 72 DLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLD---------GQE 122
DL HVITG +QGR+ +G+GQEY E Y LEY RP +W RY+ D G E
Sbjct: 85 DLPGPHVITGVQSQGRYDHGRGQEYVEEYTLEYRRPGFAEWRRYKRWDNKEVRGRNSGAE 144
Query: 123 KLTGNTNTYLEKKNHLEPPIWASK 146
L GNT+T + L P I+A++
Sbjct: 145 VLAGNTDTSTVVSHRLVPAIFATQ 168
>UniRef50_UPI00015B629D Cluster: PREDICTED: similar to CG33531-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG33531-PA - Nasonia vitripennis
Length = 990
Score = 290 bits (712), Expect = 1e-76
Identities = 152/335 (45%), Positives = 208/335 (62%), Gaps = 13/335 (3%)
Query: 153 QLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEY 212
+L ++ GGAWCP+ QI + EW+ IDL T H+IT TQGR+ +G+GQEY E Y +EY
Sbjct: 51 RLRKEAAGGAWCPKRQIESGIREWILIDLGTTHLITAIETQGRYDHGRGQEYTENYAVEY 110
Query: 213 WRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVE 272
WRP +W +YR DG E L GN +T L P I+A+++R +P+S H+RTVC+RVE
Sbjct: 111 WRPGFSEWKQYRLWDGTEVLAGNVDTSTVVSRELIPAIFATQLRLLPHSVHKRTVCLRVE 170
Query: 273 LYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDG--QWGEELRGGLGQLVDGQFGSDDIR 330
L GC GVVSY++P+ S EL D YDG ++G L GLG+L+DG+ G+D+ +
Sbjct: 171 LKGCQDLSGVVSYTIPE----SPVAELNDTSYDGVREYG-VLSAGLGRLIDGETGADNYK 225
Query: 331 E---ASKNSAWVGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIIS 386
+ K + WV W DS D V + F FD +R F AVHI+ NN F RDV VF++A +
Sbjct: 226 QDIADGKGTGWVAWMRDSFSDKYVELTFHFDGIRIFDAVHIYTNNYFTRDVQVFAKAEVW 285
Query: 387 FSIGGRHFQ-DEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 445
FS G+ + +EP+ YTY+ D ENARNVSI LH R GK +R L FAARWI++SE+ F
Sbjct: 286 FSSSGKIDEAEEPLSYTYIPDTNLENARNVSIALHGRQGKVLRFRLYFAARWIIISEVTF 345
Query: 446 DSDVAQGNYTPESMKPPVSKNKRKVISSKEVPIST 480
DS N T E+ +S + + V ++T
Sbjct: 346 DSWNPYANATEETAS-EISNEDGSGVETDNVLVAT 379
Score = 204 bits (498), Expect = 9e-51
Identities = 122/323 (37%), Positives = 179/323 (55%), Gaps = 35/323 (10%)
Query: 671 RRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYN-----GAITSEKRLVAVK 725
+ +E N+ P L + KL G G V V G+PE G S +AV
Sbjct: 668 KEIEPANI---PGQCLHTMEKLGSGHIGEVIVCAVLGLPEPAISSKFGTNGSNPLRLAVA 724
Query: 726 FL----CH----DATLKEREEFERDVRILAALSSPHLARVLG-----ACRSPPLAVVLEY 772
+ CH + + +E E R+VR LA L+ P+LARVLG A S P ++ EY
Sbjct: 725 RIPNVPCHHGYPEESAEETNEALREVRFLATLTDPNLARVLGLVCDVAETSRPWTII-EY 783
Query: 773 LELGDLCAFLRAAIP------PTAAT-------LLHIATQIAAGMQYLESLNFVHRDLAA 819
ELGDL +L+ + P P + LL++ TQIA+ M+YLES N VH+DLAA
Sbjct: 784 TELGDLAHYLQYSEPLVGTQRPNCSLNFISQNCLLYMGTQIASAMRYLESKNLVHKDLAA 843
Query: 820 RNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAF 879
RNCL+G+ Y +K++D ++ Y DY + GR P P+RW WES+L ++T S VW+F
Sbjct: 844 RNCLLGRCYSVKVTDIAMCSDLYKKDYSDIGGRPPAPIRWMPWESILLDRFTCASTVWSF 903
Query: 880 AVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWR 939
AVTL E+ S R +P++HLT+ +V+ N + + + + CP D+Y++M CW+
Sbjct: 904 AVTLWEVMSFAREKPFQHLTNEQVIQNAELMYYGGELQVLLPKPMMCPEDVYKVMCSCWK 963
Query: 940 RDELDRPTFGEIHLFLQRKSLNY 962
RDE RP+F EI+ FL+ + +Y
Sbjct: 964 RDESVRPSFREIYAFLKNVTADY 986
Score = 136 bits (330), Expect = 2e-30
Identities = 65/135 (48%), Positives = 84/135 (62%), Gaps = 1/135 (0%)
Query: 12 CIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEI 71
C + LGMESG IAD + ASS Y V P+ RL ++ GGAWCP+ QI + EW+ I
Sbjct: 19 CNSALGMESGAIADSALNASSSYVT-TVGPRYARLRKEAAGGAWCPKRQIESGIREWILI 77
Query: 72 DLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTY 131
DL T H+IT TQGR+ +G+GQEY E Y +EYWRP +W +YR DG E L GN +T
Sbjct: 78 DLGTTHLITAIETQGRYDHGRGQEYTENYAVEYWRPGFSEWKQYRLWDGTEVLAGNVDTS 137
Query: 132 LEKKNHLEPPIWASK 146
L P I+A++
Sbjct: 138 TVVSRELIPAIFATQ 152
>UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, member
2; n=2; Tetrapoda|Rep: Discoidin domain receptor family,
member 2 - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 879
Score = 277 bits (679), Expect = 1e-72
Identities = 137/293 (46%), Positives = 186/293 (63%), Gaps = 17/293 (5%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEY----NGAITSEKRLVAVKFLCHDATLKE 735
EFPR++LR+ KL EG FG V++ EA+G+ E+ + + +VAVK L D T
Sbjct: 579 EFPRNQLRLKEKLGEGQFGEVHLCEAEGLQEFLEMSPNEFSDQPNMVAVKMLRPDVTKTA 638
Query: 736 REEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA--------- 785
R +F ++++I++ L P++ R+LG C R PL ++ EY+E GDL FL
Sbjct: 639 RNDFLKEIKIISRLKHPNIIRLLGVCVRDDPLCMITEYMENGDLNQFLSQREIRSQFTKA 698
Query: 786 --IPPTAA-TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAY 842
IP + LL++A QIAAGM+YL SLNFVHRDLA RNCL+G Y IK++DFG Y
Sbjct: 699 NNIPSVSRQNLLYMAAQIAAGMKYLASLNFVHRDLATRNCLVGNSYTIKVADFGMSRNLY 758
Query: 843 TCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCE 902
+ DYY++ GR LP+RW AWES+L GK+TT SD WAF VTL E++SLC+ +PY LTD +
Sbjct: 759 SGDYYRIQGRAVLPIRWMAWESILLGKFTTCSDAWAFGVTLWEMFSLCKEQPYSVLTDEQ 818
Query: 903 VLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
V++N D G + + P CP ++ELM+ CW RD DRPTF IH FL
Sbjct: 819 VIENTGEFFRDQGRQIYLSQTPLCPGPVFELMMRCWSRDIKDRPTFETIHHFL 871
Score = 218 bits (532), Expect = 7e-55
Identities = 131/356 (36%), Positives = 187/356 (52%), Gaps = 20/356 (5%)
Query: 143 WASKDYQQGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQ 202
W Q +L ++ GAWCP + E ++L+IDLH +H IT GTQGR G+
Sbjct: 46 WYESTGPQYARLQREEGDGAWCPAGLLQPEDVQYLQIDLHELHFITLIGTQGRHARATGK 105
Query: 203 EYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSS 262
E+A AY ++Y R G+W+ +R GQ+ + GN + Y L PPI A +R IP +
Sbjct: 106 EFARAYRVDYSRNG-GRWLSWRDHQGQQVMRGNVDEYEVVLADLRPPIIARYIRVIPVTK 164
Query: 263 HRRTVCMRVELYGCYWSVGVVSYSMPKGDRR-SNG---IELTDMIYDGQWGEELR-GGLG 317
TVCMRVELYGC WS G+ SYS+P+G+ + G L D YDG + + GGLG
Sbjct: 165 VPMTVCMRVELYGCKWSDGLTSYSVPEGETYIAPGQPIAFLNDSTYDGYLEKRRQFGGLG 224
Query: 318 QLVDGQFGSDDIREASKNSAW-----VGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNN 371
QL DG G DD ++ + W +GWRNDS P V + F FD+ R FS + + CNN
Sbjct: 225 QLTDGIHGLDDFTQSLQYRVWPGYDYIGWRNDSAPRGYVEVEFHFDRPRNFSLMKVHCNN 284
Query: 372 KFMRDVLVFSEAIISFS--IGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRI 429
F + V +F +A F + G ++ EP+ V D +AR V+I L R+G +
Sbjct: 285 LFSKGVKIFQKAECLFKPRLEG-EWEAEPVVVLMVVDDKNPSARFVTIPLRQRVGSAILC 343
Query: 430 ELQFAARWILVSEIVFDSDVAQGNYTPESMKPPVSKNKRKVISSKEVPISTANQED 485
FA W++ SEI F+SD+ T + P + + EVP++ N +
Sbjct: 344 RFYFADAWMMFSEISFESDMGIAVPTLGTQSPTSAP-----AQTTEVPVALQNSTE 394
Score = 104 bits (250), Expect = 1e-20
Identities = 54/135 (40%), Positives = 76/135 (56%), Gaps = 2/135 (1%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWL 69
A C LGM I D+D+ ASS + + + PQ RL ++ GAWCP + E ++L
Sbjct: 22 ASCRYALGMHDRTIRDEDIIASSQWYE-STGPQYARLQREEGDGAWCPAGLLQPEDVQYL 80
Query: 70 EIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTN 129
+IDLH +H IT GTQGR G+E+A AY ++Y R G+W+ +R GQ+ + GN +
Sbjct: 81 QIDLHELHFITLIGTQGRHARATGKEFARAYRVDYSR-NGGRWLSWRDHQGQQVMRGNVD 139
Query: 130 TYLEKKNHLEPPIWA 144
Y L PPI A
Sbjct: 140 EYEVVLADLRPPIIA 154
>UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing
receptor 1 precursor; n=40; Mammalia|Rep: Epithelial
discoidin domain-containing receptor 1 precursor - Homo
sapiens (Human)
Length = 913
Score = 269 bits (660), Expect = 2e-70
Identities = 140/309 (45%), Positives = 187/309 (60%), Gaps = 26/309 (8%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEY---NGAITSEKR---LVAVKFLCHDAT 732
++FPR RLR KL EG FG V++ E D + + + K LVAVK L DAT
Sbjct: 603 VDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPLNVRKGHPLLVAVKILRPDAT 662
Query: 733 LKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFL--------- 782
R +F ++V+I++ L P++ R+LG C + PL ++ +Y+E GDL FL
Sbjct: 663 KNARNDFLKEVKIMSRLKDPNIIRLLGVCVQDDPLCMITDYMENGDLNQFLSAHQLEDKA 722
Query: 783 --------RAAIPPTAA--TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKI 832
+AA PT + LLH+A QIA+GM+YL +LNFVHRDLA RNCL+G+ + IKI
Sbjct: 723 AEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLATLNFVHRDLATRNCLVGENFTIKI 782
Query: 833 SDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRR 892
+DFG Y DYY+V GR LP+RW AWE +L GK+TT SDVWAF VTL E+ LCR
Sbjct: 783 ADFGMSRNLYAGDYYRVQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEVLMLCRA 842
Query: 893 RPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+P+ LTD +V++N D G + R P CP+ LYELML CW R+ RP F ++H
Sbjct: 843 QPFGQLTDEQVIENAGEFFRDQGRQVYLSRPPACPQGLYELMLRCWSRESEQRPPFSQLH 902
Query: 953 LFLQRKSLN 961
FL +LN
Sbjct: 903 RFLAEDALN 911
Score = 188 bits (457), Expect = 8e-46
Identities = 110/321 (34%), Positives = 163/321 (50%), Gaps = 11/321 (3%)
Query: 143 WASKDYQQGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQ 202
W+ + +L GAWCP + + E+L++DL +H++ GTQGR G G+
Sbjct: 53 WSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGK 112
Query: 203 EYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSS 262
E++ +Y L Y R +W+ ++ GQE ++GN + L PP+ A VRF P +
Sbjct: 113 EFSRSYRLRYSRDGR-RWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRAD 171
Query: 263 HRRTVCMRVELYGCYWSVGVVSYSMPKGDRR--SNGIELTDMIYDGQWGEELR-GGLGQL 319
+VC+RVELYGC W G++SY+ P G S + L D YDG L+ GGLGQL
Sbjct: 172 RVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQL 231
Query: 320 VDGQFGSDDIREASKNSAW-----VGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNKF 373
DG G DD R++ + W VGW N S V + FEFD++R F A+ + CNN
Sbjct: 232 ADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMH 291
Query: 374 MRDVLVFSEAIISFSIG-GRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQ 432
+ F G ++ EP+ + + AR VS+ L R+ ++++
Sbjct: 292 TLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFL 351
Query: 433 FAARWILVSEIVFDSDVAQGN 453
FA W+L SEI F SDV +
Sbjct: 352 FAGPWLLFSEISFISDVVNNS 372
Score = 92.7 bits (220), Expect = 4e-17
Identities = 47/135 (34%), Positives = 75/135 (55%), Gaps = 2/135 (1%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWL 69
A+C LGM+ I D D++ASS ++D A ++ RL GAWCP + + E+L
Sbjct: 29 AKCRYALGMQDRTIPDSDISASSSWSDSTAA-RHSRLESSDGDGAWCPAGSVFPKEEEYL 87
Query: 70 EIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTN 129
++DL +H++ GTQGR G G+E++ +Y L Y R +W+ ++ GQE ++GN +
Sbjct: 88 QVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDG-RRWMGWKDRWGQEVISGNED 146
Query: 130 TYLEKKNHLEPPIWA 144
L PP+ A
Sbjct: 147 PEGVVLKDLGPPMVA 161
>UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2
precursor; n=54; Euteleostomi|Rep: Discoidin
domain-containing receptor 2 precursor - Homo sapiens
(Human)
Length = 855
Score = 264 bits (647), Expect = 8e-69
Identities = 131/295 (44%), Positives = 181/295 (61%), Gaps = 17/295 (5%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNG------AITSEKRLVAVKFLCHDA 731
V EFPR L KL EG FG V++ E +G+ ++ ++ LVAVK L DA
Sbjct: 555 VEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADA 614
Query: 732 TLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTA 790
R +F ++++I++ L P++ +L C PL ++ EY+E GDL FL PP +
Sbjct: 615 NKNARNDFLKEIKIMSRLKDPNIIHLLSVCITDDPLCMITEYMENGDLNQFLSRHEPPNS 674
Query: 791 AT----------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
++ L +ATQIA+GM+YL SLNFVHRDLA RNCL+GK Y IKI+DFG
Sbjct: 675 SSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRN 734
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y+ DYY++ GR LP+RW +WES+L GK+TT SDVWAF VTL E ++ C+ +PY L+D
Sbjct: 735 LYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSD 794
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+V++N D G + + CP +Y+LML CWRRD +RP+F EIHL L
Sbjct: 795 EQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRPSFQEIHLLL 849
Score = 240 bits (588), Expect = 1e-61
Identities = 126/322 (39%), Positives = 178/322 (55%), Gaps = 12/322 (3%)
Query: 143 WASKDYQQGLQLNQDIKGGAWCPRSQITTEST-EWLEIDLHTVHVITGAGTQGRFGNGQG 201
W+ + +L+ + GAWCP + + E+L+IDLHT+H IT GTQGR G G
Sbjct: 52 WSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHG 111
Query: 202 QEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYS 261
E+A Y + Y R +W+ +R+ G++ L GN+N Y LEPPI A VRFIP +
Sbjct: 112 IEFAPMYKINYSRDGT-RWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVT 170
Query: 262 SHRRTVCMRVELYGCYWSVGVVSYSMPKGDR----RSNGIELTDMIYDGQWGEELRGGLG 317
H VCMRVELYGC W G+VSY+ P G + + I L D +YDG G + GLG
Sbjct: 171 DHSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLG 230
Query: 318 QLVDGQFGSDDIREASKNSAW-----VGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNN 371
QL DG G DD + + W VGWRN+S + + I+FEFD++R F+ + + CNN
Sbjct: 231 QLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNN 290
Query: 372 KFMRDVLVFSEAIISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIEL 431
F + V +F E F ++ I + V D + +AR V++ LHHR+ ++ +
Sbjct: 291 MFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQY 350
Query: 432 QFAARWILVSEIVFDSDVAQGN 453
FA W++ SEI F SD A N
Sbjct: 351 HFADTWMMFSEITFQSDAAMYN 372
Score = 111 bits (266), Expect = 1e-22
Identities = 59/136 (43%), Positives = 81/136 (59%), Gaps = 3/136 (2%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTEST-EW 68
A C PLGM G I D+D+TASS +++ A + GRL+ + GAWCP + + E+
Sbjct: 28 AICRYPLGMSGGQIPDEDITASSQWSESTAA-KYGRLDSEEGDGAWCPEIPVEPDDLKEF 86
Query: 69 LEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNT 128
L+IDLHT+H IT GTQGR G G E+A Y + Y R +W+ +R+ G++ L GN+
Sbjct: 87 LQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGT-RWISWRNRHGKQVLDGNS 145
Query: 129 NTYLEKKNHLEPPIWA 144
N Y LEPPI A
Sbjct: 146 NPYDIFLKDLEPPIVA 161
>UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate
discoidin domain receptor family, member 2; n=4; Danio
rerio|Rep: Novel protein similar to vertebrate discoidin
domain receptor family, member 2 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 804
Score = 264 bits (646), Expect = 1e-68
Identities = 137/299 (45%), Positives = 190/299 (63%), Gaps = 19/299 (6%)
Query: 677 NVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEY--NGAITSEKR----LVAVKFLCHD 730
+V EFPR RL KL EG FG V++ EA+G+ E+ GA E+ LVAVK L D
Sbjct: 500 SVAEFPRQRLLFREKLGEGQFGEVHLCEAEGLAEFLGEGAPLPEQDGRPVLVAVKQLRAD 559
Query: 731 ATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA---- 785
AT R +F ++++I++ L++P++ ++L C S PL +V EY+E GDL FL
Sbjct: 560 ATSNARNDFLKEIKIMSRLNNPNIIQLLCVCVSSDPLCMVTEYMENGDLNMFLSQREIES 619
Query: 786 -------IPPTA-ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
IP + A LLH++ QI++GM+YL SLNFVHRDLA RNCL+ + IKISDFG
Sbjct: 620 TLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVHRDLATRNCLLDRHLTIKISDFGM 679
Query: 838 DNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
Y+ DYY++ GR LP+RW AWES+L GK+TT SDVWAF VTL EI++LC+ +PY
Sbjct: 680 SRNLYSSDYYRIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSL 739
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
L+D +V++N + G + P CP L++LM+ CW RD DRP+F ++H L+
Sbjct: 740 LSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLMMRCWSRDITDRPSFNKLHQALR 798
Score = 181 bits (440), Expect = 1e-43
Identities = 108/286 (37%), Positives = 151/286 (52%), Gaps = 13/286 (4%)
Query: 175 EWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTG 234
++L+IDL + +T TQGR+ G E+A Y LEY R +W+ +R+ G E + G
Sbjct: 39 QYLQIDLRQLIFLTVVATQGRYARNSGIEFARKYRLEYSRDG-HRWISWRNRFGNEIIMG 97
Query: 235 NTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCMRVELYGCYWSVGVVSYSMPKGD-RR 293
N NTY L PPI +R IP + TVCMRVEL+GC W G+++YS P+G
Sbjct: 98 NVNTYDTVVRDLHPPIITRFLRLIPVTDAVHTVCMRVELFGCAWQDGLMAYSSPEGQIMM 157
Query: 294 SNGIELT---DMIYDGQW-GEELRGGLGQLVDGQFGSDDIREASKNSAW-----VGWRND 344
+ G +T D YDG +L GGLGQL DG G DD E+ + W VGWRND
Sbjct: 158 APGFPITSLNDSTYDGPLERRKLSGGLGQLADGVVGLDDFVESRQYRLWPGYDYVGWRND 217
Query: 345 S-RPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISFSIG-GRHFQDEPIHYT 402
P + F+FD+ R F+++ + NN F V +FS F + ++ EP+ +
Sbjct: 218 GLGPGYVEMEFQFDRQRNFTSMKVHSNNMFSMGVKIFSSVSCVFKLHLISEWESEPVEFH 277
Query: 403 YVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFDSD 448
V D +AR V+I L HR +R FA W++ SEI F S+
Sbjct: 278 TVIDDRNPSARYVTIPLKHRSATALRCRFYFADTWMMFSEISFQSE 323
Score = 59.3 bits (137), Expect = 5e-07
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Query: 67 EWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTG 126
++L+IDL + +T TQGR+ G E+A Y LEY R +W+ +R+ G E + G
Sbjct: 39 QYLQIDLRQLIFLTVVATQGRYARNSGIEFARKYRLEYSRDG-HRWISWRNRFGNEIIMG 97
Query: 127 NTNTYLEKKNHLEPPI 142
N NTY L PPI
Sbjct: 98 NVNTYDTVVRDLHPPI 113
>UniRef50_UPI0000E48069 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 913
Score = 257 bits (630), Expect = 9e-67
Identities = 128/310 (41%), Positives = 189/310 (60%), Gaps = 27/310 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEY--NG-----AITSEKRLVAVKFLCHDAT 732
E+PR +L + L EG FG V++ EA+ + +Y NG E+ LVAVK L DA+
Sbjct: 598 EYPRSQLNFLELLGEGMFGEVHLCEAEDIQDYIRNGFPFENKNKGERTLVAVKMLRKDAS 657
Query: 733 LKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFL--------- 782
R +F ++++I++ L P++ R+L AC P +++EY+E GDL FL
Sbjct: 658 KNARADFMKEMKIMSQLRDPNIVRLLAACTEDEPYCMIVEYMENGDLNQFLYEREGFEVG 717
Query: 783 ----RAAIPP------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKI 832
A + + L+++ TQIA+GM+YL ++NFVHRDLA RNCL+GK Y I+I
Sbjct: 718 LNNCNANLSNCNKSSISVGALVYMITQIASGMKYLSNMNFVHRDLATRNCLVGKSYTIRI 777
Query: 833 SDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRR 892
+DFG Y+ +YY+++GR LP+RW AWES+L GK+T+K+DVWAF VTL E+ LCR
Sbjct: 778 ADFGMSRNLYSSNYYRIEGRAVLPIRWMAWESILLGKFTSKTDVWAFGVTLWEVMMLCRE 837
Query: 893 RPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+PY LTD +V++N DG + + P CP+D++ LM CW + RPTF +H
Sbjct: 838 QPYSRLTDEQVIENTGQFFEKDGTPVYLAKPPQCPKDIHNLMKRCWTSEPGQRPTFDFLH 897
Query: 953 LFLQRKSLNY 962
FLQ +++ Y
Sbjct: 898 TFLQARNIGY 907
Score = 213 bits (520), Expect = 2e-53
Identities = 119/310 (38%), Positives = 165/310 (53%), Gaps = 11/310 (3%)
Query: 152 LQLNQDIKGGAWCPRSQITTES--TEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYV 209
L LNQ GAWCP + S E+L++DL + VI TQGR+ G EY +
Sbjct: 62 LHLNQG--AGAWCPVNAQPESSGHYEYLQVDLLNLTVILALSTQGRWDTNFGNEYTSRFR 119
Query: 210 LEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCM 269
LE R W+RY + G+E GN +T + H+ PPI A +R IP + VCM
Sbjct: 120 LELSRDGGKTWIRYVQMTGEEVFVGNRDTNSQITVHISPPIVAQVLRIIPVVLIQTPVCM 179
Query: 270 RVELYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGEELR-GGLGQLVDGQFGSDD 328
R+ELYGC W + SYSMP GD R + D YDG E R GLGQL DG G +
Sbjct: 180 RIELYGCKWLDHLKSYSMPTGDTRGEYV-FEDDTYDGYTFEGQRMNGLGQLTDGMLGHSN 238
Query: 329 IREASKN----SAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAI 384
R + N WVGWRN S P+P I FEFD +R F+++ NN F +V +F
Sbjct: 239 YRLSPYNVPQGYEWVGWRNTSHPNPE-ITFEFDSLRNFTSLGFHVNNYFTNNVEIFDAIE 297
Query: 385 ISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIV 444
+ FSI HF I+ T D ++AR +++ L +R+ +W+++ L +W+LVSE+
Sbjct: 298 VQFSIRKGHFSPRSIYTTIRPDSDHQDARWITVNLGNRVAQWLKVALVHRGKWVLVSEVS 357
Query: 445 FDSDVAQGNY 454
F+S+ N+
Sbjct: 358 FESEDIPDNF 367
Score = 91.9 bits (218), Expect = 8e-17
Identities = 51/137 (37%), Positives = 72/137 (52%), Gaps = 4/137 (2%)
Query: 12 CIAPLGMESGLIADKDVTASSCYNDGNVA--PQNGRLNQDIKGGAWCPRSQITTEST--E 67
C PLGM I D+ ++ASS Y + ++ PQN RL+ + GAWCP + S E
Sbjct: 26 CRYPLGMNDKAIKDEQLSASSVYENNTLSFGPQNARLHLNQGAGAWCPVNAQPESSGHYE 85
Query: 68 WLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGN 127
+L++DL + VI TQGR+ G EY + LE R W+RY + G+E GN
Sbjct: 86 YLQVDLLNLTVILALSTQGRWDTNFGNEYTSRFRLELSRDGGKTWIRYVQMTGEEVFVGN 145
Query: 128 TNTYLEKKNHLEPPIWA 144
+T + H+ PPI A
Sbjct: 146 RDTNSQITVHISPPIVA 162
>UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 12
SCAF15007, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 878
Score = 257 bits (629), Expect = 1e-66
Identities = 134/288 (46%), Positives = 183/288 (63%), Gaps = 19/288 (6%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEY--NGAITSEKR----LVAVKFLCHDATL 733
EFPR +L KL EG FG V++ EA+G+PE+ G+ E+ LVAVK L DAT
Sbjct: 584 EFPRQQLIFREKLGEGQFGEVHLCEAEGLPEFLGEGSPLPERDGHSVLVAVKQLRADATS 643
Query: 734 KEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA------- 785
+ R +F ++++I++ L+ P++ R+L C S PL +V EY+E GDL FL
Sbjct: 644 QARNDFLKEIKIMSRLNDPNIIRLLCVCVSSDPLCMVTEYMENGDLNMFLSQREIESTLT 703
Query: 786 ----IPPTAAT-LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
IP + + LLH+A QI++GM+YL SLNFVHRDLA RNCL+ + IKI+DFG
Sbjct: 704 HANNIPSVSLSDLLHMAVQISSGMKYLASLNFVHRDLATRNCLLDRRLTIKIADFGMSRN 763
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y+ DYY++ GR LP+RW AWES+L GK+TT SDVWAF VTL EI++LC+ +PY L+D
Sbjct: 764 LYSSDYYRIQGRAVLPIRWMAWESILLGKFTTASDVWAFGVTLWEIFTLCKEQPYSLLSD 823
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+V++N + G + P CP L+ELM+ CW RD DRP F
Sbjct: 824 EQVIENTGEFFRNQGRQIFLYAPPLCPPSLFELMMRCWSRDIHDRPNF 871
Score = 123 bits (296), Expect = 3e-26
Identities = 62/148 (41%), Positives = 80/148 (54%), Gaps = 5/148 (3%)
Query: 143 WASKDYQQGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQ 202
W Q +LNQ+ GAWCP ++L++DL + +T GTQGRF G
Sbjct: 25 WYKTTGPQYARLNQEKGDGAWCPEHL----DNQYLQVDLGRLTFLTVVGTQGRFARNTGN 80
Query: 203 EYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSS 262
E+ AY L Y R L W +R+ G + GN NTY N L PPI +R +P +
Sbjct: 81 EFTSAYRLNYSRDGL-LWKSWRNRLGNALIEGNKNTYASVINDLHPPIITRYIRLLPVTK 139
Query: 263 HRRTVCMRVELYGCYWSVGVVSYSMPKG 290
H TVCMRVELYGC W G++SYS P+G
Sbjct: 140 HSPTVCMRVELYGCPWEDGLISYSAPEG 167
Score = 95.9 bits (228), Expect = 5e-18
Identities = 55/133 (41%), Positives = 69/133 (51%), Gaps = 6/133 (4%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWL 69
A C LGME G I D+ +TASS + PQ RLNQ+ GAWCP ++L
Sbjct: 1 AHCRYALGMEDGRIPDEAITASSQWYK-TTGPQYARLNQEKGDGAWCPEHL----DNQYL 55
Query: 70 EIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTN 129
++DL + +T GTQGRF G E+ AY L Y R L W +R+ G + GN N
Sbjct: 56 QVDLGRLTFLTVVGTQGRFARNTGNEFTSAYRLNYSRDGL-LWKSWRNRLGNALIEGNKN 114
Query: 130 TYLEKKNHLEPPI 142
TY N L PPI
Sbjct: 115 TYASVINDLHPPI 127
Score = 81.4 bits (192), Expect = 1e-13
Identities = 54/175 (30%), Positives = 81/175 (46%), Gaps = 8/175 (4%)
Query: 312 LRGGLGQLVDGQFGSDDIREASKNSAW-----VGWRNDSRPDPPVIIFEF--DKVREFSA 364
L GG+GQL DG G DD + + W +GW+NDS + EF D+ R F++
Sbjct: 217 LSGGMGQLTDGVIGLDDFLKTHQYHVWPGYDYLGWKNDSLGTQGYVEMEFVFDRQRNFTS 276
Query: 365 VHIFCNNKFMRDVLVFSEAIISFSIGG-RHFQDEPIHYTYVQDKIFENARNVSIKLHHRI 423
+ + NN F V +FS F ++ EP+ + V D +AR V++ L+ R
Sbjct: 277 MKVHSNNMFRSGVKIFSAVSCWFKPRLIASWEPEPVVFKTVLDDKNPSARYVTVSLNRRA 336
Query: 424 GKWVRIELQFAARWILVSEIVFDSDVAQGNYTPESMKPPVSKNKRKVISSKEVPI 478
K +R FA W++ SEI F S V + + T E S + R P+
Sbjct: 337 AKSLRCRFYFADVWMMFSEISFQSVVFKLHLTSEFFPAAPSPSARSPPEDSNTPV 391
>UniRef50_UPI0000DB6BCC Cluster: PREDICTED: similar to Discoidin
domain receptor CG33531-PA; n=1; Apis mellifera|Rep:
PREDICTED: similar to Discoidin domain receptor
CG33531-PA - Apis mellifera
Length = 1243
Score = 248 bits (608), Expect = 4e-64
Identities = 134/300 (44%), Positives = 177/300 (59%), Gaps = 9/300 (3%)
Query: 150 QGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYV 209
Q ++ Q+ GGAWCP++QI++ E+LEIDL H+I TQGRFGNGQGQEYAEA+
Sbjct: 381 QNARIRQEKNGGAWCPKAQISSAIREYLEIDLTRDHLIAWTETQGRFGNGQGQEYAEAFF 440
Query: 210 LEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCM 269
LEYWR KW +Y++L G L GN+NTYL +K L+ P ASKVRF+PYS H RTVCM
Sbjct: 441 LEYWRDT--KWHQYKNLKGDRVLRGNSNTYLVEKQKLDLPFVASKVRFVPYSQHPRTVCM 498
Query: 270 RVELYGCYWSVGVVSYSMPKGD-RRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFG-- 325
RVE+YGC W V SYSM KG G + D YDG + L GLGQL DG G
Sbjct: 499 RVEIYGCIWEQYVASYSMIKGPILGPGGKNIEDSSYDGIEIDSLLVNGLGQLTDGILGEV 558
Query: 326 SDDIREASKNSAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAII 385
S+ + ++ + WVGW + + I F F ++REF I ++ FS I
Sbjct: 559 SEILTSSTNGTNWVGWSDRTTVQ---ITFSFQELREFENCSIHVARIPELEIETFSLIHI 615
Query: 386 SFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVF 445
FS G +++ E + D A +SI L RIG++V++E AA+W+L+SEI F
Sbjct: 616 WFSSDGENYESEAEKLVGLIDSSSSIAETISIPLQSRIGRFVKMEFDLAAKWLLLSEITF 675
Score = 166 bits (403), Expect = 3e-39
Identities = 123/391 (31%), Positives = 193/391 (49%), Gaps = 53/391 (13%)
Query: 588 DFKDSNTALSDSSNYDYAVPELSSAPLLTKRMGETLSQQATELVGEPMDTLPDLGTRRSL 647
DFK N++ S + + VP + + +K++ + S + + E D+ T++
Sbjct: 881 DFK-CNSSFMTSKSTEIIVPTTTYS---SKKIFYSQSGKLNQRNYEGYYAATDILTKKK- 935
Query: 648 NPSVRSKQSTRSPSQ-QEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEAD 706
S S +P Q +E L L +E+ NV RHRLR++ KL EG FG V++ EA
Sbjct: 936 --ETSSTSSPFTPLQIREKGLCLLHTIESYNVQRISRHRLRILDKLGEGNFGLVHLCEAK 993
Query: 707 GVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPL 766
G+ ++ V V+ L R +F +D+ +LA L + ++A+++ P
Sbjct: 994 GITNPEIEAIQNRQTVIVRSLWRGVVDSLRLDFTKDMHVLAMLQNSNIAKMIALVEEEPF 1053
Query: 767 AVVLEYLELGDLCAFL--RAAIPP----TAATLLHIATQIAAGMQYLESLNFVHRDLAAR 820
+ EY + GDL FL R + + + L QIA+GM+YLES+N H DLAAR
Sbjct: 1054 GAIFEYGQFGDLPTFLENRENLDNKEDISYGSRLSFIIQIASGMKYLESMNIAHCDLAAR 1113
Query: 821 NCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFA 880
NC++ +IK LRW AWE+VL GK + ++DVW+FA
Sbjct: 1114 NCIVCLDLKIK-------------------------LRWMAWEAVLLGKRSCRADVWSFA 1148
Query: 881 VTLHEIYSLCRRRPYEHLTDCEVLDNLSH-LQADDGMFECVD---------RAPG----C 926
VT+ EI+ C+ PY LT ++L+N H Q + + + D R P C
Sbjct: 1149 VTIWEIFRNCKEIPYADLTVAQILENYGHWYQRETSIDKEYDDNNDKRNQPRIPSQSDHC 1208
Query: 927 PRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
P +LY +M +CW +RP+F EIHL+L++
Sbjct: 1209 PDNLYRIMKKCWSTRVEERPSFEEIHLYLEK 1239
Score = 162 bits (393), Expect = 5e-38
Identities = 77/136 (56%), Positives = 94/136 (69%), Gaps = 2/136 (1%)
Query: 11 QCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLE 70
QCI PLGME G I D +TASS Y +V PQN R+ Q+ GGAWCP++QI++ E+LE
Sbjct: 350 QCIFPLGMEEGKIPDDAITASSSYETKSVGPQNARIRQEKNGGAWCPKAQISSAIREYLE 409
Query: 71 IDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNT 130
IDL H+I TQGRFGNGQGQEYAEA+ LEYWR KW +Y++L G L GN+NT
Sbjct: 410 IDLTRDHLIAWTETQGRFGNGQGQEYAEAFFLEYWRDT--KWHQYKNLKGDRVLRGNSNT 467
Query: 131 YLEKKNHLEPPIWASK 146
YL +K L+ P ASK
Sbjct: 468 YLVEKQKLDLPFVASK 483
>UniRef50_UPI00015B46B5 Cluster: PREDICTED: similar to CG33531-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG33531-PA - Nasonia vitripennis
Length = 1140
Score = 244 bits (596), Expect = 1e-62
Identities = 129/313 (41%), Positives = 186/313 (59%), Gaps = 15/313 (4%)
Query: 150 QGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYV 209
Q ++ Q+ GGAWCP++QI+++ E+LE+DL H+IT TQGRFGNG+GQEYAEA+
Sbjct: 60 QNARIRQEKNGGAWCPKAQISSDIREYLEVDLTKDHLITWTETQGRFGNGEGQEYAEAFF 119
Query: 210 LEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCM 269
LEYWR KW Y++L G L GN+NTYL ++ LE P AS+VRF+PYS H RTVCM
Sbjct: 120 LEYWRDL--KWHPYKNLRGDRVLRGNSNTYLVERQKLELPFVASRVRFVPYSQHPRTVCM 177
Query: 270 RVELYGCYWSVGVVSYSMPKGD-RRSNGIELTDMIYDG-QWGEELRGGLGQLVDGQFGSD 327
RVE+YGC W + SY++P G+ N L D YDG + L GLGQL D G +
Sbjct: 178 RVEIYGCAWEQRIASYTIPAGEIHGPNNSNLDDSSYDGSEVNGTLSNGLGQLTDNVLGDE 237
Query: 328 -DIREASKNSAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIIS 386
+ +S + WVGW N + ++FEF +VREF I + R++ V+
Sbjct: 238 QEFLSSSSGNNWVGWGNREIVE---LVFEFKEVREFDNCSIHVAHVPRREIEVW------ 288
Query: 387 FSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIVFD 446
FS G+++Q + + NA V I L + G++V++E++ ++W+L+SE+ F
Sbjct: 289 FSYDGKNYQTS-TEKIDISNDFKPNAAVVEIPLQLKTGRFVKLEIKPRSKWLLISEVTFG 347
Query: 447 SDVAQGNYTPESM 459
S N T ++M
Sbjct: 348 SVPGLRNLTNDAM 360
Score = 221 bits (540), Expect = 7e-56
Identities = 120/318 (37%), Positives = 180/318 (56%), Gaps = 13/318 (4%)
Query: 652 RSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEY 711
+S S +P Q + + L N+ + RHRLR++ K EG+FG VY+ EA G+
Sbjct: 610 QSSSSLFTPLQIQESVQLSNTSSIYNIQQISRHRLRILDKFGEGSFGLVYLCEAKGIQSP 669
Query: 712 NGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLE 771
+ +++V V+ L T +++F +D+ +LAA+ ++AR++ P+ V E
Sbjct: 670 DIGTIRNRQIVIVRSLWRGVTDSLKKDFMKDMHLLAAIRDLNVARIIALVEEEPMGAVFE 729
Query: 772 YLELGDLCAFLRAA-------IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLI 824
Y ELGDL F+++ + + LL+ TQIA+GM+YLE+L H DLAARNC +
Sbjct: 730 YGELGDLPTFMKSGSENGNDDLTMSYGCLLNFVTQIASGMKYLENLKIPHCDLAARNCFV 789
Query: 825 GKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLH 884
K IK+SD Y +YY +PLRW AWE+VL GK +++SDVW++AVT+
Sbjct: 790 NKNLIIKVSDHALYCGKYDHEYYVNGYYAKIPLRWMAWEAVLMGKCSSQSDVWSYAVTVW 849
Query: 885 EIYSLCRRRPYEHLTDCEVLDNLS--HLQADDGMFECVDRA---PG-CPRDLYELMLECW 938
EI+S C PY LT +VL+N S + + + + R P CPR+LY +M +CW
Sbjct: 850 EIFSSCSELPYAELTSEQVLENCSRWYQSTPNNNQQQLPRVLPQPSLCPRELYHMMSKCW 909
Query: 939 RRDELDRPTFGEIHLFLQ 956
R DRP F EI+LFL+
Sbjct: 910 SRRAEDRPNFEEIYLFLK 927
Score = 158 bits (383), Expect = 8e-37
Identities = 74/135 (54%), Positives = 94/135 (69%), Gaps = 2/135 (1%)
Query: 12 CIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEI 71
CI PLGME G I D +TASS Y +V PQN R+ Q+ GGAWCP++QI+++ E+LE+
Sbjct: 30 CILPLGMEEGKIPDHAITASSSYEMKSVGPQNARIRQEKNGGAWCPKAQISSDIREYLEV 89
Query: 72 DLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTY 131
DL H+IT TQGRFGNG+GQEYAEA+ LEYWR KW Y++L G L GN+NTY
Sbjct: 90 DLTKDHLITWTETQGRFGNGEGQEYAEAFFLEYWRDL--KWHPYKNLRGDRVLRGNSNTY 147
Query: 132 LEKKNHLEPPIWASK 146
L ++ LE P AS+
Sbjct: 148 LVERQKLELPFVASR 162
>UniRef50_UPI000065F9C5 Cluster: Epithelial discoidin
domain-containing receptor 1 precursor (EC 2.7.10.1)
(Epithelial discoidin domain receptor 1) (Tyrosine
kinase DDR) (Discoidin receptor tyrosine kinase)
(Tyrosine-protein kinase CAK) (Cell adhesion kinase)
(TRK E) (Protein-tyrosine ki; n=3; Euteleostomi|Rep:
Epithelial discoidin domain-containing receptor 1
precursor (EC 2.7.10.1) (Epithelial discoidin domain
receptor 1) (Tyrosine kinase DDR) (Discoidin receptor
tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell
adhesion kinase) (TRK E) (Protein-tyrosine ki - Takifugu
rubripes
Length = 864
Score = 238 bits (583), Expect = 5e-61
Identities = 134/313 (42%), Positives = 182/313 (58%), Gaps = 29/313 (9%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADG-----VPEYNGAITSEKRL-VAVKFLCHDA 731
V E R L KL EG FG V++ E + + E+ + + L VAVK L DA
Sbjct: 550 VPELSRQCLIFKEKLGEGQFGEVHLCEIENPQDLPILEFPFNVRKGRPLLVAVKILRPDA 609
Query: 732 TLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAI----- 786
+ R +F ++V+IL+ L P++ R+LG C S L +V EY+E GDL +L +
Sbjct: 610 SKNARNDFLKEVKILSRLKDPNIIRLLGVCVSNDLCMVTEYMECGDLNQYLSHRVLLDKT 669
Query: 787 -----PPTAA--TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIG--KG---------Y 828
PT + L+ +A+QIA+GM++L SLNFVHRDLA RNCL+G +G
Sbjct: 670 GPSNDAPTVSYPALISMASQIASGMKFLSSLNFVHRDLATRNCLVGGERGDSGDDAGGER 729
Query: 829 QIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
IKI+DFG Y DYY++ GR LP+RW AWE +L GK+TT SDVWAF VTL E+ S
Sbjct: 730 HIKIADFGMSRNLYAGDYYRIQGRAVLPIRWMAWECILMGKFTTASDVWAFGVTLWEMLS 789
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+C+ +PY +LTD +V+DN D + R CP+ LYELML CW RD RP+F
Sbjct: 790 VCQEQPYSNLTDEQVIDNAGEFFRDQSRQVYLGRPAVCPQGLYELMLSCWNRDCKLRPSF 849
Query: 949 GEIHLFLQRKSLN 961
+IH FL ++N
Sbjct: 850 SDIHSFLTEDAMN 862
Score = 182 bits (444), Expect = 3e-44
Identities = 108/314 (34%), Positives = 160/314 (50%), Gaps = 12/314 (3%)
Query: 143 WASKDYQQGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQ 202
W+ + +L+ GAWCP + +E+L++DLH +H + GTQGR +G GQ
Sbjct: 25 WSDSTEAKHGRLSTGEGDGAWCPAGAVFPSESEYLQVDLHRLHFLALVGTQGRHADGHGQ 84
Query: 203 EYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSS 262
E+ Y L Y R + KW+ + GQ+ ++GN NTY L PPI A VRF P +
Sbjct: 85 EFTRNYRLRYSRDGV-KWLTWTDHWGQDVVSGNQNTYDIVLKDLGPPIVARMVRFYPLAD 143
Query: 263 HRRTVCMRVELYGCYWSVGVVSYSMPKGD-RRSNG--IELTDMIYDGQWGEELR-GGLGQ 318
+VC+RVELYGC W G+ +Y+ P G +G I L D YDG ++ GGLGQ
Sbjct: 144 RVMSVCLRVELYGCLWDDGLEAYTAPVGHIMHLSGIPINLNDSTYDGSTEHGMQFGGLGQ 203
Query: 319 LVDGQFGSDDIREASKNSAW-----VGWRNDSRPDPPV-IIFEFDKVREFSAVHIFCNNK 372
L DG G +D + + W VGW ++ V I F F R F+ + + NN+
Sbjct: 204 LCDGVLGGNDFTQTKELRVWPGYDYVGWSREALGQGSVDIEFHFKLPRIFNTMQVHSNNR 263
Query: 373 FMRDVLVFSEAIISFSIGGRHFQDEPIHYTY-VQDKIFENARNVSIKLHHRIGKWVRIEL 431
+ V VF++ F G P+ ++D ++R +S+ L R + +R +
Sbjct: 264 HTQGVRVFNKVECQFKPGILQPWSSPLTLDVPLEDLKDPSSRTISLPLGARPAQILRCKF 323
Query: 432 QFAARWILVSEIVF 445
FA RW+L+SEI F
Sbjct: 324 YFADRWLLISEITF 337
Score = 113 bits (273), Expect = 2e-23
Identities = 59/135 (43%), Positives = 79/135 (58%), Gaps = 2/135 (1%)
Query: 10 AQCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWL 69
AQC LGME G I D DVTASS ++D A ++GRL+ GAWCP + +E+L
Sbjct: 1 AQCRYALGMEDGTIPDSDVTASSAWSDSTEA-KHGRLSTGEGDGAWCPAGAVFPSESEYL 59
Query: 70 EIDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTN 129
++DLH +H + GTQGR +G GQE+ Y L Y R + KW+ + GQ+ ++GN N
Sbjct: 60 QVDLHRLHFLALVGTQGRHADGHGQEFTRNYRLRYSRDGV-KWLTWTDHWGQDVVSGNQN 118
Query: 130 TYLEKKNHLEPPIWA 144
TY L PPI A
Sbjct: 119 TYDIVLKDLGPPIVA 133
>UniRef50_Q70W12 Cluster: Discoidin receptor; n=1; Ciona
intestinalis|Rep: Discoidin receptor - Ciona
intestinalis (Transparent sea squirt)
Length = 457
Score = 237 bits (579), Expect = 1e-60
Identities = 128/348 (36%), Positives = 194/348 (55%), Gaps = 25/348 (7%)
Query: 634 PMDTLPDLGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLA 693
P T P R + S ST Q+ ++ L L EFPR +L ++ +L
Sbjct: 88 PWSTPPTGKRNRKNKHTTASAASTLQADFQDEMMSLMS-LHGDKPPEFPREKLEVVEQLG 146
Query: 694 EGAFGTVYVAEADG-------VP-EYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
EG FG V + +A P +++G + E LVAVK L DAT +E+F ++VR+
Sbjct: 147 EGQFGEVQLCKAHNSLRKLVSAPFQFSGEL-DEPVLVAVKVLRADATSNAKEDFLKEVRV 205
Query: 746 LAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAI-----PPTA--------- 790
++ + P++ ++ C P A++ EY+E GDL +LR+ P++
Sbjct: 206 MSQMQDPNIVHLIAVCTNDEPYAMITEYMENGDLNQYLRSCADKMNSDPSSKENSLFSSN 265
Query: 791 ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVD 850
L+++ QIA+GM+YL S FVHRDLA RNCL+ + I+I+DFG Y DYY++
Sbjct: 266 EVLINMCVQIASGMRYLSSHKFVHRDLATRNCLVDSNHSIRIADFGMSRNMYQSDYYRIQ 325
Query: 851 GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHL 910
GR LP+RW +WE VL GK+++ SD WAF VTL EI+S C+ +P+ LTD +V++N+ H+
Sbjct: 326 GRAVLPIRWMSWECVLMGKFSSASDAWAFGVTLWEIFSFCKLQPHNSLTDQQVIENMHHV 385
Query: 911 QADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRK 958
G + R CP L+ L+ +CW+R DRPTF ++H +L K
Sbjct: 386 FKRTGEEVHLQRPKRCPATLFNLIRQCWKRQPEDRPTFEQLHGYLLEK 433
>UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 797
Score = 225 bits (550), Expect = 4e-57
Identities = 112/283 (39%), Positives = 169/283 (59%), Gaps = 15/283 (5%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
T + E R +L +S++ +G FG V + + E R VAVK L H + +
Sbjct: 517 TTLPEIARDKLICVSRIGQGEFGEVDLCQL------------ENRKVAVKKL-HGISQAD 563
Query: 736 REEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATLL 794
F R++R+L +L P++ V+G C P+ ++EY+E GDL +++ + +
Sbjct: 564 EFSFHREIRVLGSLKHPNVVEVVGVCTIQKPILCIMEYMENGDLKSYILKNPTIQTSQCI 623
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
I TQ+AAG+ YLES NFVHRD+AARNCL+ +KI+DFG Y+ +YYKV+G+
Sbjct: 624 SICTQLAAGLAYLESCNFVHRDIAARNCLVDGEGNVKIADFGMARSLYSQEYYKVEGKFV 683
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
LP+RW AWE++L GK++T SDVW F VT+ EI+SLC +PY +TD +V++NL + +
Sbjct: 684 LPIRWMAWEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTG 743
Query: 915 GMFECVDRAPGCPRDLY-ELMLECWRRDELDRPTFGEIHLFLQ 956
+ + + R CP LY E +L CW + RP+F +HL LQ
Sbjct: 744 SLKQVLSRPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQ 786
Score = 221 bits (541), Expect = 6e-56
Identities = 113/303 (37%), Positives = 172/303 (56%), Gaps = 8/303 (2%)
Query: 150 QGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYV 209
Q + +Q+ GAWCP++QI + S EWL+I VIT TQGRF +G+G EYA A+
Sbjct: 55 QHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFK 114
Query: 210 LEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCM 269
++YWRP L W Y+ E + N +T + HL+ I A ++R +P S+ RTVCM
Sbjct: 115 IQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCM 174
Query: 270 RVELYGCYWSVGVVSYSMPKGDRRSNGIELTDMIYDGQWGE--ELRGGLGQLVDGQFGSD 327
RVE++GC + +V Y++ +GD +S GI D YDG L GG+G+L DG+ G +
Sbjct: 175 RVEVFGCPFDDSLVFYNVDQGDLQS-GISYHDFSYDGNLANSPHLTGGIGKLYDGEVGKN 233
Query: 328 DIREASKNSAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFCNNKFMRDVLVFSEAIISF 387
++ + WVGWR R + FEF ++R S + I +N+F + FS A + F
Sbjct: 234 NV--FVNHHKWVGWRR-KRNGNVKLAFEFSELRNISGILIHTSNEFKKSAKAFSSATVLF 290
Query: 388 SIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFA--ARWILVSEIVF 445
SI G+ F D +H+ +D E R + I +++RI K +I L F + W+ +SE+ F
Sbjct: 291 SINGKDFSDTIVHFNNPEDTESEVPRWIRIPVNNRIAKVAKIRLNFGTDSDWLFISEVNF 350
Query: 446 DSD 448
+S+
Sbjct: 351 ESN 353
Score = 115 bits (276), Expect = 7e-24
Identities = 53/136 (38%), Positives = 79/136 (58%)
Query: 11 QCIAPLGMESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLE 70
+C LGM + I D+ ++ASS ++ + PQ+ R +Q+ GAWCP++QI + S EWL+
Sbjct: 24 ECSHQLGMSNRKIRDEQISASSSFDLQSTGPQHARAHQESGSGAWCPKNQINSLSKEWLQ 83
Query: 71 IDLHTVHVITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNT 130
I VIT TQGRF +G+G EYA A+ ++YWRP L W Y+ E + N +T
Sbjct: 84 ISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDT 143
Query: 131 YLEKKNHLEPPIWASK 146
+ HL+ I A +
Sbjct: 144 EHAIRRHLDRAIIARR 159
>UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=73; Gnathostomata|Rep: BDNF/NT-3 growth
factors receptor precursor - Homo sapiens (Human)
Length = 822
Score = 206 bits (504), Expect = 2e-51
Identities = 122/295 (41%), Positives = 171/295 (57%), Gaps = 28/295 (9%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
T V RH + + +L EGAFG V++AE YN +K LVAVK L DA+
Sbjct: 528 TFVQHIKRHNIVLKRELGEGAFGKVFLAEC-----YNLCPEQDKILVAVKTL-KDASDNA 581
Query: 736 REEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA----AI---- 786
R++F R+ +L L H+ + G C PL +V EY++ GDL FLRA A+
Sbjct: 582 RKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAE 641
Query: 787 --PPTAAT---LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
PPT T +LHIA QIAAGM YL S +FVHRDLA RNCL+G+ +KI DFG +
Sbjct: 642 GNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 701
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
Y+ DYY+V G LP+RW ES++ K+TT+SDVW+ V L EI++ ++P+ L++
Sbjct: 702 YSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY-GKQPWYQLSNN 760
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EV++ ++ + + R CP+++YELML CW+R+ R IH LQ
Sbjct: 761 EVIECITQGRV-------LQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQ 808
>UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=17; Euteleostomi|Rep: BDNF/NT-3 growth
factors receptor precursor - Gallus gallus (Chicken)
Length = 818
Score = 204 bits (499), Expect = 7e-51
Identities = 119/295 (40%), Positives = 169/295 (57%), Gaps = 28/295 (9%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
T V RH + + +L EGAFG V++AE YN +K LVAVK L DA+
Sbjct: 524 TFVQHIKRHNIVLKRELGEGAFGKVFLAEC-----YNLCPEQDKILVAVKTL-KDASDNA 577
Query: 736 REEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP------ 788
R++F R+ +L L H+ + G C PL +V EY++ GDL FLRA P
Sbjct: 578 RKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAE 637
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
T + +LHIA QIAAGM YL S +FVHRDLA RNCL+G+ +KI DFG +
Sbjct: 638 GNRPAELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDV 697
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
Y+ DYY+V G LP+RW ES++ K+TT+SDVW+ V L EI++ ++P+ L++
Sbjct: 698 YSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTY-GKQPWYQLSNN 756
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EV++ ++ + + R CP+++Y+LML CW+R+ R EIH LQ
Sbjct: 757 EVIECITQGRV-------LQRPRTCPKEVYDLMLGCWQREPHMRLNIKEIHSLLQ 804
>UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5;
Caenorhabditis|Rep: Receptor tyrosine kinase -
Caenorhabditis elegans
Length = 928
Score = 201 bits (491), Expect = 6e-50
Identities = 124/318 (38%), Positives = 178/318 (55%), Gaps = 30/318 (9%)
Query: 654 KQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNG 713
+Q+ R PSQ+ I + V E +L + K+ EG FG V+ G+ +G
Sbjct: 564 QQARRFPSQEPI------DDNSYKVFEITPSQLSVREKIGEGQFGVVH----SGIYT-SG 612
Query: 714 AITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEY 772
E VAVK HDAT ER + E+++R +A P++ +++G C L V EY
Sbjct: 613 LFAPEPMAVAVKKCRHDATNAERAQLEQEIRAVATFDHPNVIKLIGVCYMDNSLLAVFEY 672
Query: 773 LELGDLCAFLRAAIPPTA----------ATLLHIATQIAAGMQYLESLNFVHRDLAARNC 822
+ GDL L+ +PP A L+IATQIA GM+YL S++FVHRDLA RNC
Sbjct: 673 MVHGDLHELLKVRVPPADHDMGGITEANAEFLYIATQIALGMEYLASMSFVHRDLATRNC 732
Query: 823 LIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVT 882
L+G IKI+DFG +Y DYYK+ R +P+RW + E++ +G+++ SDVW+F VT
Sbjct: 733 LVGDTRTIKIADFGLMRTSYGSDYYKMLHRSWMPVRWMSKEAIEQGRFSEASDVWSFGVT 792
Query: 883 LHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDE 942
L EI+S R+PYE ++ +V++ L A+ + EC CP ++Y LM+ECW +
Sbjct: 793 LWEIWSF-GRQPYEGASNQQVIE----LVANRHLLEC---PHNCPTNIYSLMVECWHENI 844
Query: 943 LDRPTFGEIHLFLQRKSL 960
RPTF EI LQ SL
Sbjct: 845 ERRPTFSEIRSRLQSWSL 862
>UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 985
Score = 199 bits (486), Expect = 3e-49
Identities = 111/283 (39%), Positives = 164/283 (57%), Gaps = 22/283 (7%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYN---GAITSEKR---LVAVKFLCHDATLKEREEF 739
+R + L G FG V +AE + + A +KR LVA+K L A E F
Sbjct: 689 VREVRPLGVGQFGHVILAETVNLSLKDLKMSATNDDKRVCVLVAMKKLKDGADSTTLEAF 748
Query: 740 ERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAA--IPP--------- 788
E++++ ++ L+ ++ RVLG C +++EY+E GDL +L PP
Sbjct: 749 EKEIKFMSRLNHENVVRVLGVCPVRSAFIMMEYMENGDLSQYLTKYEFAPPGVCIGQLML 808
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
A+TL+H+A QIAAGM+YL NF+HRDLA RNCL+G Y +KI+DFG Y+ DYYK
Sbjct: 809 PASTLVHMALQIAAGMRYLAERNFIHRDLATRNCLVGAKYVVKIADFGMSRSLYSNDYYK 868
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
+ GR LP+RW A E GK++ K+DVWAF V + EI++ +R+PY+ ++D +V++N
Sbjct: 869 LRGRAMLPIRWMAKE-CFYGKFSQKTDVWAFGVVMWEIFTFSKRQPYDEMSDQQVIENAI 927
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G + R CP+++YE+ML+CW D R TF E+
Sbjct: 928 E---KSGRI-LLARPHNCPKEVYEVMLQCWENDPETRATFEEL 966
>UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3;
Endopterygota|Rep: Tyrosine-protein kinase receptor -
Anopheles gambiae str. PEST
Length = 646
Score = 197 bits (481), Expect = 1e-48
Identities = 113/282 (40%), Positives = 165/282 (58%), Gaps = 21/282 (7%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
+ V ++ +R + +L EGAFG VY E + + NG E+ VAVK L +A+ K
Sbjct: 364 SRVPQYTLQDVRFVEELGEGAFGKVYKGE---LTQKNG----ERIFVAVKALKENASAKT 416
Query: 736 REEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAATL- 793
+ +F+R++ +++ L ++ +LG + PL ++ EY+ GDL FL A P +L
Sbjct: 417 QADFKREIELISDLKHDNIVCILGVVLKEEPLCMLFEYMAQGDLHEFLIANSPNEGKSLS 476
Query: 794 ----LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV 849
L IA QI GM+YL S ++VHRDLAARNCL+G +KISDFG + Y+ DYY+V
Sbjct: 477 QLQFLLIAQQICDGMEYLASHHYVHRDLAARNCLVGDNLTVKISDFGLSRDIYSSDYYRV 536
Query: 850 DGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSH 909
+ LP+RW ES+L GK+TT+SDVW+F V L EIYS +PY ++ EV++ +
Sbjct: 537 QSKSLLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSY-GLQPYYGYSNQEVINMVRA 595
Query: 910 LQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
Q + C + CP +Y LM+ECW + RPTF EI
Sbjct: 596 RQ----LLPCPE---SCPSAVYSLMVECWHEQAVRRPTFPEI 630
>UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2;
Eumetazoa|Rep: Tyrosine-protein kinase receptor -
Aplysia californica (California sea hare)
Length = 1145
Score = 195 bits (475), Expect = 5e-48
Identities = 112/296 (37%), Positives = 166/296 (56%), Gaps = 32/296 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFP +R + +L EGAFG VY E G+ + T VA+K L +A K + +F
Sbjct: 565 EFPMPNIRFLQELGEGAFGKVYKGELVGLYGESSVTT-----VAIKTLKENALPKVQNDF 619
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAAT------ 792
R+V +++ + P++ +LG C + P+ ++ EY+ GDL +L + P + T
Sbjct: 620 RREVDLMSDMRHPNIVCLLGVCMKQEPMCMLFEYMAQGDLHEYLLSHSPHSDVTAAEDDS 679
Query: 793 ------------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
+LH++TQ+AAGM+YL S +FVHRDLAARN L+ G +KISDFG +
Sbjct: 680 GTGGGHILEYSEMLHVSTQVAAGMEYLASHHFVHRDLAARNILVADGLTVKISDFGLSRD 739
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y+ DYY+V + LP+RW E++L GK+TT SDVWAF V L E++S +PY ++
Sbjct: 740 VYSSDYYRVQSKSLLPVRWMPPEAILYGKFTTDSDVWAFGVVLWEVFSY-GLQPYYGFSN 798
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EV++ + Q + C + CP +Y LM+ECW RP F EIH L+
Sbjct: 799 QEVIEMIRSRQ----ILGCPEE---CPARIYGLMVECWHEMPARRPPFREIHTRLR 847
>UniRef50_P04629 Cluster: High affinity nerve growth factor receptor
precursor; n=28; Eumetazoa|Rep: High affinity nerve
growth factor receptor precursor - Homo sapiens (Human)
Length = 796
Score = 195 bits (475), Expect = 5e-48
Identities = 111/283 (39%), Positives = 163/283 (57%), Gaps = 32/283 (11%)
Query: 691 KLAEGAFGTVYVAEADGV-PEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAAL 749
+L EGAFG V++AE + PE +K LVAVK L +A+ R++F+R+ +L L
Sbjct: 515 ELGEGAFGKVFLAECHNLLPE------QDKMLVAVKAL-KEASESARQDFQREAELLTML 567
Query: 750 SSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTA---------------ATL 793
H+ R G C PL +V EY+ GDL FLR+ P L
Sbjct: 568 QHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQL 627
Query: 794 LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRV 853
L +A+Q+AAGM YL L+FVHRDLA RNCL+G+G +KI DFG + Y+ DYY+V GR
Sbjct: 628 LAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRT 687
Query: 854 PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQAD 913
LP+RW ES+L K+TT+SDVW+F V L EI++ ++P+ L++ E +D ++ +
Sbjct: 688 MLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTY-GKQPWYQLSNTEAIDCITQGRE- 745
Query: 914 DGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
++R CP ++Y +M CW+R+ R + ++H LQ
Sbjct: 746 ------LERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQ 782
>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=53; Euteleostomi|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Homo sapiens (Human)
Length = 869
Score = 194 bits (474), Expect = 7e-48
Identities = 110/304 (36%), Positives = 162/304 (53%), Gaps = 38/304 (12%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+E+PR+ + + + EGAFG V+ A A G+ Y +VAVK L +A+ + +
Sbjct: 568 LEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQAD 622
Query: 739 FERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATLLH-- 795
F+R+ ++A +P++ ++LG C P+ ++ EY+ GDL FLR+ P T +L H
Sbjct: 623 FQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD 682
Query: 796 ----------------------IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKIS 833
IA Q+AAGM YL FVHRDLA RNCL+G+ +KI+
Sbjct: 683 LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA 742
Query: 834 DFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR 893
DFG Y+ DYYK + +P+RW ES+ +YTT+SDVWA+ V L EI+S +
Sbjct: 743 DFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY-GLQ 801
Query: 894 PYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHL 953
PY + EV+ + D + C + CP +LY LM CW + DRP+F IH
Sbjct: 802 PYYGMAHEEVI----YYVRDGNILSCPE---NCPVELYNLMRLCWSKLPADRPSFTSIHR 854
Query: 954 FLQR 957
L+R
Sbjct: 855 ILER 858
>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=18; Gnathostomata|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Gallus gallus (Chicken)
Length = 947
Score = 192 bits (469), Expect = 3e-47
Identities = 108/302 (35%), Positives = 160/302 (52%), Gaps = 36/302 (11%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+E+PR+ + + + EGAFG V+ A A G+ Y +VAVK L +A+ + +
Sbjct: 648 LEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFT-----MVAVKMLKEEASADMQAD 702
Query: 739 FERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATLLH-- 795
F+R+ ++A +P++ ++LG C P+ ++ EY+ GDL +LR P +L+
Sbjct: 703 FQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGG 762
Query: 796 --------------------IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDF 835
IA Q+AAGM YL FVHRDLA RNCL+G+ +KI+DF
Sbjct: 763 LEARACLLNPLALCCTSQLCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADF 822
Query: 836 GTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPY 895
G Y+ DYYK + +P+RW ES+ +YTT+SDVWA+ V L EI+S +PY
Sbjct: 823 GLSRNMYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSY-GMQPY 881
Query: 896 EHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+ EV+ + D + C D CP +LY LM CW + DRP+F IH L
Sbjct: 882 YGMAHEEVI----YYVRDGNILSCPD---NCPLELYNLMRLCWSKLPADRPSFASIHRIL 934
Query: 956 QR 957
+R
Sbjct: 935 ER 936
>UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror2 precursor; n=2; Sophophora|Rep:
Tyrosine-protein kinase transmembrane receptor Ror2
precursor - Drosophila melanogaster (Fruit fly)
Length = 724
Score = 188 bits (458), Expect = 6e-46
Identities = 115/293 (39%), Positives = 160/293 (54%), Gaps = 29/293 (9%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADG-VPEYNGAITSEKRLVAVKFLCHDATLKERE 737
+E+PR + + L +GAFG V+ A A G VP+ E LVAVK L DA+ + +
Sbjct: 434 LEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPD------QEDLLVAVKMLKDDASDQMQM 487
Query: 738 EFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIP------PTA 790
+FER+ +LA P++ R+LG C P+ ++ EY+ GDL FLRA P PT
Sbjct: 488 DFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQ 547
Query: 791 ATL-------LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
L L +A IAAGM YL FVHRDLA RNCLI + +KI+DFG ++ Y
Sbjct: 548 DRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYL 607
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
DYYK D +P+RW ES+L K++ +SDVWA+ + L E++S +PY LT EV
Sbjct: 608 QDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFA-LQPYFGLTHEEV 666
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ + + + C D P +Y LM CW R +RP F EI+ +Q
Sbjct: 667 IKYIK----EGNVLGCPDNT---PLSVYALMRRCWNRKPSERPGFAEINHCIQ 712
>UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror precursor; n=1; Drosophila
melanogaster|Rep: Tyrosine-protein kinase transmembrane
receptor Ror precursor - Drosophila melanogaster (Fruit
fly)
Length = 685
Score = 188 bits (458), Expect = 6e-46
Identities = 105/277 (37%), Positives = 158/277 (57%), Gaps = 21/277 (7%)
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
F + + +L EGAFG VY + + IT VA+K L +A++K +++F+
Sbjct: 405 FTLQDVEFLEELGEGAFGKVYKGQL--LQPNKTTIT-----VAIKALKENASVKTQQDFK 457
Query: 741 RDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAATL-----L 794
R++ +++ L ++ +LG P ++ EY+ GDL FL + P +L L
Sbjct: 458 REIELISDLKHQNIVCILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFL 517
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
IA QI+ GMQYL + ++VHRDLAARNCL+ +G +KISDFG + Y+ DYY+V +
Sbjct: 518 QIALQISEGMQYLSAHHYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSKSL 577
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
LP+RW ES+L GK+TT+SDVW+F V L EIYS +PY ++ EV++ + Q
Sbjct: 578 LPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSY-GMQPYYGFSNQEVINLIRSRQ--- 633
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ CP +Y LM+ECW + RPTF +I
Sbjct: 634 ----LLSAPENCPTAVYSLMIECWHEQSVKRPTFTDI 666
>UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase receptor;
n=5; Endopterygota|Rep: Muscle-specific tyrosine kinase
receptor - Aedes aegypti (Yellowfever mosquito)
Length = 666
Score = 187 bits (455), Expect = 1e-45
Identities = 115/294 (39%), Positives = 161/294 (54%), Gaps = 29/294 (9%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEK-RLVAVKFLCHDATLKERE 737
+EFPR+ + I L +GAFG V+ A+A G+ I E LVAVK L +A+ +
Sbjct: 376 LEFPRNNIIYIKDLGQGAFGRVFQAKAPGL------IAGEDFTLVAVKMLKDEASQDLQV 429
Query: 738 EFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIP--------- 787
+FER+ +LA P++ ++LG C P+ ++ E++ GDL FLR P
Sbjct: 430 DFEREACLLAEFDHPNIVKLLGVCAIGRPMCLLFEFMARGDLNEFLRQCSPFAQQNRADN 489
Query: 788 ----PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
+ LL IA+QIA+GM YL FVHRDLA RNCLI +KI+DFG ++ Y
Sbjct: 490 ITTELSHGDLLSIASQIASGMVYLSERKFVHRDLATRNCLIDDNMVVKIADFGLSHKIYL 549
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
DYYK D +P+RW ES+L KYT +SDVWA+ V L EI+S +PY +T EV
Sbjct: 550 QDYYKGDENDAIPIRWMPLESILYNKYTIESDVWAYGVCLWEIFSFA-MQPYYGMTHEEV 608
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ + + M C + P +Y+LM +CW R DRP+F I LQ+
Sbjct: 609 VKFVK----EGNMLSCPENT---PLTVYDLMRKCWSRKPADRPSFPIIFQKLQQ 655
>UniRef50_Q16288 Cluster: NT-3 growth factor receptor precursor;
n=49; Euteleostomi|Rep: NT-3 growth factor receptor
precursor - Homo sapiens (Human)
Length = 839
Score = 186 bits (452), Expect = 3e-45
Identities = 118/311 (37%), Positives = 172/311 (55%), Gaps = 45/311 (14%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
T V R + + +L EGAFG V++AE YN + T +K LVAVK L D TL
Sbjct: 528 TYVQHIKRRDIVLKRELGEGAFGKVFLAEC-----YNLSPTKDKMLVAVKAL-KDPTLAA 581
Query: 736 REEFERDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLRAAIP------- 787
R++F+R+ +L L H+ + G C PL +V EY++ GDL FLRA P
Sbjct: 582 RKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVD 641
Query: 788 --PTAAT-------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
P A +LHIA+QIA+GM YL S +FVHRDLA RNCL+G +KI DFG
Sbjct: 642 GQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMS 701
Query: 839 NEAYTCDYYK--------------VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLH 884
+ Y+ DYY+ V G LP+RW ES++ K+TT+SDVW+F V L
Sbjct: 702 RDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILW 761
Query: 885 EIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELD 944
EI++ ++P+ L++ EV++ ++ + ++R CP+++Y++ML CW+R+
Sbjct: 762 EIFTY-GKQPWFQLSNTEVIECITQGRV-------LERPRVCPKEVYDVMLGCWQREPQQ 813
Query: 945 RPTFGEIHLFL 955
R EI+ L
Sbjct: 814 RLNIKEIYKIL 824
>UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (Xe-InsR) (XTK-1b) [Contains: Insulin receptor
subunit alpha; Insulin receptor subunit beta]; n=6;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (Xe-InsR) (XTK-1b) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Xenopus laevis (African clawed frog)
Length = 1362
Score = 177 bits (431), Expect = 1e-42
Identities = 106/284 (37%), Positives = 157/284 (55%), Gaps = 26/284 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRL-VAVKFLCHDATLKEREE 738
E PR ++ ++ +L +G+FG VY A + I E + VAVK + A+L+ER E
Sbjct: 1006 EVPRDKINLLRELGQGSFGMVYEGIAKDI------IKGEPEVRVAVKTVNESASLRERIE 1059
Query: 739 FERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP---------- 787
F + ++ A + H+ R+LG + P V++E + GDL ++LR+ P
Sbjct: 1060 FLNEASVMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLA 1119
Query: 788 PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
PT ++ +A +I+ GM YL + FVHRDLAARNC++ Y +KI DFG + Y DYY
Sbjct: 1120 PTLKEIIQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETDYY 1179
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
+ G+ LP+RW + ES+ G +T SDVW+F V L EI SL +PY+ L++ +VL
Sbjct: 1180 RKGGKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLA-EQPYQGLSNEQVL--- 1235
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G +D CP L+ LM CW+ + RPTF EI
Sbjct: 1236 -KFVMDGG---SLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEI 1275
>UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (CD220 antigen) [Contains: Insulin receptor subunit
alpha; Insulin receptor subunit beta]; n=100;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Homo sapiens (Human)
Length = 1382
Score = 176 bits (429), Expect = 2e-42
Identities = 105/283 (37%), Positives = 160/283 (56%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++ ++ +L +G+FG VY A + + +E R VAVK + A+L+ER EF
Sbjct: 1017 EVSREKITLLRELGQGSFGMVYEGNARDIIKGE----AETR-VAVKTVNESASLRERIEF 1071
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP----------P 788
+ ++ + H+ R+LG + P VV+E + GDL ++LR+ P P
Sbjct: 1072 LNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPP 1131
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
T ++ +A +IA GM YL + FVHRDLAARNC++ + +KI DFG + Y DYY+
Sbjct: 1132 TLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYR 1191
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP+RW A ES+ G +TT SD+W+F V L EI SL +PY+ L++ +VL +
Sbjct: 1192 KGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLA-EQPYQGLSNEQVLKFVM 1250
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
DG + +D+ CP + +LM CW+ + RPTF EI
Sbjct: 1251 -----DGGY--LDQPDNCPERVTDLMRMCWQFNPKMRPTFLEI 1286
>UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming
protein ros; n=3; root|Rep: Tyrosine-protein kinase
transforming protein ros - Avian sarcoma virus (strain
UR2)
Length = 402
Score = 175 bits (426), Expect = 5e-42
Identities = 117/303 (38%), Positives = 162/303 (53%), Gaps = 28/303 (9%)
Query: 669 LKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEA-DGVPEYNGAITSEKRLVAVKFL 727
L + E ++ FPR +L + L GAFG VY A D + + +G E R VAVK L
Sbjct: 81 LPSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSG----ESR-VAVKTL 135
Query: 728 CHDATLKEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAI 786
AT +E+ EF ++ +++ PH+ ++LG C + P ++LE +E GDL ++LR A
Sbjct: 136 KRGATDQEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGAR 195
Query: 787 PP-------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIG-KGYQ-----IKIS 833
T LL I I G YLE + F+HRDLAARNCL+ K Y +KI
Sbjct: 196 KQKFQSPLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIG 255
Query: 834 DFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR 893
DFG + Y DYY+ G LP+RW A ES++ G +T SDVWAF V + E +L ++
Sbjct: 256 DFGLARDIYKNDYYRKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTL-GQQ 314
Query: 894 PYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHL 953
PY L++ EVL H G E + CP D+ +LM CW +D +RPTF I
Sbjct: 315 PYPGLSNIEVL----HHVRSGGRLESPN---NCPDDIRDLMTRCWAQDPHNRPTFFYIQH 367
Query: 954 FLQ 956
LQ
Sbjct: 368 KLQ 370
>UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=47;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] - Homo
sapiens (Human)
Length = 1367
Score = 175 bits (425), Expect = 6e-42
Identities = 103/283 (36%), Positives = 161/283 (56%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++ M +L +G+FG VY A GV + E R VA+K + A+++ER EF
Sbjct: 993 EVAREKITMSRELGQGSFGMVYEGVAKGVVKDE----PETR-VAIKTVNEAASMRERIEF 1047
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA----------IPP 788
+ ++ + H+ R+LG + P V++E + GDL ++LR+ PP
Sbjct: 1048 LNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPP 1107
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
+ + ++ +A +IA GM YL + FVHRDLAARNC++ + + +KI DFG + Y DYY+
Sbjct: 1108 SLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYR 1167
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP+RW + ES+ G +TT SDVW+F V L EI +L +PY+ L++ +VL
Sbjct: 1168 KGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLA-EQPYQGLSNEQVL---- 1222
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G+ +D+ CP L+ELM CW+ + RP+F EI
Sbjct: 1223 RFVMEGGL---LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1262
>UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=25;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] -
Xenopus laevis (African clawed frog)
Length = 1358
Score = 174 bits (424), Expect = 8e-42
Identities = 102/283 (36%), Positives = 159/283 (56%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ M +L +G+FG VY A GV + + VA+K + A+++ER EF
Sbjct: 989 EVPREKITMNRELGQGSFGMVYEGIAKGVVK-----DEAETKVAIKTVNEAASMRERIEF 1043
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP----------P 788
+ ++ + H+ R+LG + P V++E + GDL ++LR+ P P
Sbjct: 1044 LNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNSGQPTP 1103
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
+ ++ +A +IA GM YL + FVHRDLAARNC++ + + +KI DFG + Y DYY+
Sbjct: 1104 SLKKMIQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETDYYR 1163
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP+RW + ES+ G +TT SDVW+F V L EI +L +PY+ +++ +VL
Sbjct: 1164 KGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLA-EQPYQGMSNEQVL---- 1218
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G+ E D CP L+ELM CW+ + RP+F EI
Sbjct: 1219 RFVMEGGLLEKPD---NCPDMLFELMRMCWQFNPKMRPSFLEI 1258
>UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2;
Branchiostoma floridae|Rep: Tyrosine-protein kinase
receptor - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 797
Score = 174 bits (423), Expect = 1e-41
Identities = 101/285 (35%), Positives = 156/285 (54%), Gaps = 28/285 (9%)
Query: 683 RHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERD 742
R + + +L EGAFG VY+ + + + A LVAVK L + R++F+R+
Sbjct: 507 RDTIHFVGELGEGAFGRVYLGKCEKLKPDEDA-----SLVAVKTLKEMSVEDARKDFDRE 561
Query: 743 VRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTA------AT--- 792
+L + ++ + G C P ++ EY+E GDL +LR+ P A AT
Sbjct: 562 AELLTNMQHENIVKFYGVCTEGEPWLMIFEYMENGDLNNYLRSHGPDAAFLIKNPATHKE 621
Query: 793 -----LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
LL I+ Q+A+G++Y+ S +FVHRDLA RNCL+G +KI DFG + Y+ DYY
Sbjct: 622 LSIVELLQISVQVASGVEYMASQHFVHRDLATRNCLVGDKLVVKIGDFGMSRDIYSTDYY 681
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
+V G LP+RW ESVL K+T +SD+W+F V L EI++ ++P+ L + EV++ +
Sbjct: 682 RVGGHTMLPVRWMPPESVLYRKFTIESDIWSFGVVLWEIFTF-GKQPWYELANHEVIECI 740
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+ + C GCPR++ LML CW++ R +IH
Sbjct: 741 T----SGRLLGC---PRGCPRNVRALMLGCWKKTPAQRTNIQDIH 778
>UniRef50_Q17305 Cluster: G01D9.2 protein; n=3; Caenorhabditis|Rep:
G01D9.2 protein - Caenorhabditis briggsae
Length = 737
Score = 174 bits (423), Expect = 1e-41
Identities = 98/305 (32%), Positives = 167/305 (54%), Gaps = 12/305 (3%)
Query: 150 QGLQLNQDIKGGAWCPRSQITTESTEWLEIDLHTVHVITGAGTQGRFGNGQGQEYAEAYV 209
Q +L+ ++ GAWCP+ QI ++S E+L++ L+ +IT TQGR+GNG G+E+A Y+
Sbjct: 25 QNARLHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYM 84
Query: 210 LEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNHLEPPIWASKVRFIPYSSHRRTVCM 269
++Y RP +W+RY + G + GN +T L+PPI AS++R +P S + RTVCM
Sbjct: 85 IDYMRPG-SQWIRYLNRSGHVYMDGNFDTTTPVIRALDPPIVASRIRIVPSSKNTRTVCM 143
Query: 270 RVELYGCYWSVGVVSYS-MPKGDRRSNGIELTDMIYDGQWGEE--LRGGLGQLVDGQFGS 326
R E++G + GV+ YS +P G R +M + Q E + GLG L DG
Sbjct: 144 RAEIHG-WKHEGVIYYSTVPDGSRLDTLDFKDNMFENSQMYTESGITRGLGLLTDGYVAQ 202
Query: 327 DDIREASK-NSAWVGWRNDSRPDPPVIIFEFDKVREFSAVHIFC-NNKFMRDVLVFSEAI 384
E ++ N++W+GW D+ I+FEF+++ F+ V + N+ ++FS+
Sbjct: 203 TSPFEKNQMNNSWIGWNRDTTDGRVTILFEFEEIHNFTDVVLATFGNRIDGIDVIFSQDG 262
Query: 385 ISFSIGGRHFQDEPIHYTYVQDKIFENARNVSIKLHHRIGKWVRIELQFAARWILVSEIV 444
+F + + E + + + LH+R G+ VRI ++F++ W+ ++E+
Sbjct: 263 KTFPLFSQISSSERQTLNNTSRRY-----DFRVPLHNRAGRKVRISIKFSSDWMFLTEVH 317
Query: 445 FDSDV 449
F S +
Sbjct: 318 FTSGI 322
Score = 119 bits (287), Expect = 3e-25
Identities = 53/129 (41%), Positives = 84/129 (65%), Gaps = 1/129 (0%)
Query: 18 MESGLIADKDVTASSCYNDGNVAPQNGRLNQDIKGGAWCPRSQITTESTEWLEIDLHTVH 77
M++G + D +TASS ++ +V PQN RL+ ++ GAWCP+ QI ++S E+L++ L+
Sbjct: 1 MQNGDVLDAQITASSSFDKQSVGPQNARLHSELASGAWCPKPQINSKSYEFLQVTLNDTF 60
Query: 78 VITGAGTQGRFGNGQGQEYAEAYVLEYWRPKLGKWVRYRSLDGQEKLTGNTNTYLEKKNH 137
+IT TQGR+GNG G+E+A Y+++Y RP +W+RY + G + GN +T
Sbjct: 61 LITSVETQGRYGNGTGREFASHYMIDYMRPG-SQWIRYLNRSGHVYMDGNFDTTTPVIRA 119
Query: 138 LEPPIWASK 146
L+PPI AS+
Sbjct: 120 LDPPIVASR 128
Score = 66.9 bits (156), Expect = 2e-09
Identities = 49/157 (31%), Positives = 76/157 (48%), Gaps = 18/157 (11%)
Query: 752 PHLARVLGACRSPPLAVVLEYLELGDLCAF-LRAAIPPTAATLLHIATQIAAGMQYLESL 810
P + + G S L +LE +E G + F L + L I + + M YLES+
Sbjct: 561 PRIVELYGVDESYNL--LLEPVEYGCIRNFWLASETSLDTEFLARICKDVFSAMTYLESI 618
Query: 811 NFVHRDLAARNCLIGKGYQIKI-SDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGK 869
VH N L+ + KI S G + A LR++A ES++ +
Sbjct: 619 RIVHGHFTPNNILLDGEFHAKICSPRGPSHHAQ--------------LRYSAPESIVNNE 664
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
+T KSD WA + T++E+ CR+RPYE LT+ +++DN
Sbjct: 665 FTHKSDAWAVSTTVYEMAYQCRQRPYEELTNEQIVDN 701
>UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18;
Euteleostomi|Rep: Transmembrane receptor PTK7-2 - Homo
sapiens (Human)
Length = 1030
Score = 172 bits (419), Expect = 3e-41
Identities = 106/291 (36%), Positives = 163/291 (56%), Gaps = 24/291 (8%)
Query: 671 RRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHD 730
+R T++ + FPR L+ I+ L + FG V++A+A G+ E G + LV VK L
Sbjct: 741 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEE--GVAET---LVLVKSL-QS 794
Query: 731 ATLKEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAI--- 786
+++ +F R++ + L+ ++ R+LG CR + P +VLEY++LGDL FLR +
Sbjct: 795 KDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKD 854
Query: 787 ------PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
P + + + TQ+A GM++L + FVH+DLAARNCL+ Q+K+S G +
Sbjct: 855 EKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKD 914
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y +YY + +PLRW + E++L G ++TKSDVWAF V + E+++ P+ D
Sbjct: 915 VYNSEYYHF-RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFT-HGEMPHGGQAD 972
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
EV L+ LQA + + GCP LY LM CW DRP+F EI
Sbjct: 973 DEV---LADLQAGKAR---LPQPEGCPSKLYRLMQRCWALSPKDRPSFSEI 1017
>UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precursor;
n=29; Tetrapoda|Rep: Tyrosine-protein kinase-like 7
precursor - Homo sapiens (Human)
Length = 1070
Score = 172 bits (419), Expect = 3e-41
Identities = 106/291 (36%), Positives = 163/291 (56%), Gaps = 24/291 (8%)
Query: 671 RRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHD 730
+R T++ + FPR L+ I+ L + FG V++A+A G+ E G + LV VK L
Sbjct: 781 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEE--GVAET---LVLVKSL-QS 834
Query: 731 ATLKEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAI--- 786
+++ +F R++ + L+ ++ R+LG CR + P +VLEY++LGDL FLR +
Sbjct: 835 KDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKD 894
Query: 787 ------PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
P + + + TQ+A GM++L + FVH+DLAARNCL+ Q+K+S G +
Sbjct: 895 EKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKD 954
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y +YY + +PLRW + E++L G ++TKSDVWAF V + E+++ P+ D
Sbjct: 955 VYNSEYYHF-RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFT-HGEMPHGGQAD 1012
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
EV L+ LQA + + GCP LY LM CW DRP+F EI
Sbjct: 1013 DEV---LADLQAGKAR---LPQPEGCPSKLYRLMQRCWALSPKDRPSFSEI 1057
>UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca
CG10244-PA; n=3; Endopterygota|Rep: PREDICTED: similar
to Cad96Ca CG10244-PA - Apis mellifera
Length = 657
Score = 172 bits (418), Expect = 4e-41
Identities = 107/282 (37%), Positives = 155/282 (54%), Gaps = 23/282 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPRHRL++ + L EG FG V+ EA + +GAI +VAVK L +AT +ER +
Sbjct: 353 EFPRHRLKVFNILGEGCFGQVWKCEALDIDGKSGAI-----IVAVKTLKENATERERLDL 407
Query: 740 ERDVRILAALSS-PHLARVLGACRS-PPLAVVLEYLELGDLCAFLRAAIPP--------T 789
+++R++ L P++ R+LG C P+ V+LEY+ G L +FLRA+ T
Sbjct: 408 AQELRVMKNLDPHPNVVRLLGCCTEREPMFVILEYVSGGKLQSFLRASREERNHGGPGLT 467
Query: 790 AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV 849
+ L QIA GM+YL S +HRDLAARN LI + K++DFG + Y+
Sbjct: 468 SRDLTGFVYQIAKGMEYLASKGIIHRDLAARNILIDENRACKVADFGFARDVAANQIYER 527
Query: 850 DGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSH 909
LP+RW A ES+ ++ KSD+W+F V + EI +L PY L EV+ +
Sbjct: 528 KSEGRLPIRWMAPESLYDNIFSVKSDIWSFGVLIWEIVTL-GSTPYPGLAAAEVMRRIK- 585
Query: 910 LQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+G +DR C R+LY +M CW +D RP+FGE+
Sbjct: 586 ----EGY--RLDRPEHCKRELYNIMYYCWDKDPACRPSFGEL 621
>UniRef50_P14616 Cluster: Insulin receptor-related protein precursor
(EC 2.7.10.1) (IRR) (IR- related receptor) [Contains:
Insulin receptor-related protein alpha chain; Insulin
receptor-related protein beta chain]; n=14; Eutheria|Rep:
Insulin receptor-related protein precursor (EC 2.7.10.1)
(IRR) (IR- related receptor) [Contains: Insulin
receptor-related protein alpha chain; Insulin
receptor-related protein beta chain] - Homo sapiens
(Human)
Length = 1297
Score = 172 bits (418), Expect = 4e-41
Identities = 104/283 (36%), Positives = 156/283 (55%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ +I +L +G+FG VY A G+ E VA+K + A+ +E EF
Sbjct: 973 EVPREQISIIRELGQGSFGMVYEGLARGLEA-----GEESTPVALKTVNELASPRECIEF 1027
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP----------P 788
++ ++ A H+ R+LG + P V++E + GDL + LR+ P P
Sbjct: 1028 LKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQP 1087
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
++ +A +IA GM YL + FVHRDLAARNC++ + + +KI DFG + Y DYY+
Sbjct: 1088 ALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYR 1147
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP+RW A ES+ G +TT SDVW+F V L EI +L +PY+ L++ +VL
Sbjct: 1148 KGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLA-EQPYQGLSNEQVL---- 1202
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G+ E ++ GCP L ELM CW+ + RP+F I
Sbjct: 1203 KFVMDGGVLEELE---GCPLQLQELMSRCWQPNPRLRPSFTHI 1242
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 172 bits (418), Expect = 4e-41
Identities = 109/280 (38%), Positives = 152/280 (54%), Gaps = 24/280 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY A V + G VAVK L D + +F
Sbjct: 365 EICRTDIMMKHKLGGGQYGEVYEA----VWKRYG------NTVAVKTLKEDTMALK--DF 412
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPT--AATLLHI 796
+ I+ + P+L +++G C R PP ++ E++ G+L FLR+A T A LL++
Sbjct: 413 LEEAAIMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYM 472
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQIA+GM YLES N++HRDLAARNCL+G +K++DFG D Y P
Sbjct: 473 ATQIASGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGL-ARLMRDDTYTAHAGAKFP 531
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A E + K++TKSDVWAF V L EI + PY + +V L D G
Sbjct: 532 IKWTAPEGLAYNKFSTKSDVWAFGVLLWEI-ATYGMSPYPAIDLTDVYHKL-----DKGY 585
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
++R PGCP ++Y+LM +CW+ D DRPTF IH L+
Sbjct: 586 --RMERPPGCPPEVYDLMRQCWQWDATDRPTFKSIHHALE 623
>UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror
CG4926-PA; n=3; Endopterygota|Rep: PREDICTED: similar to
Ror CG4926-PA - Apis mellifera
Length = 529
Score = 171 bits (417), Expect = 6e-41
Identities = 108/287 (37%), Positives = 151/287 (52%), Gaps = 34/287 (11%)
Query: 683 RHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERD 742
R L + ++ EG FG VY E I K +VA+K L A + E+F R+
Sbjct: 202 RESLAFLQEIGEGCFGKVYKGEL--------CIGDSKEIVAIKVLKETAPREAEEDFMRE 253
Query: 743 VRILAALSSPHLARVLGAC----RSPPLAVVLEYLELGDLCAFLRA-----------AIP 787
V I++ ++ + GA S P +V EY+ GDL LR+ +
Sbjct: 254 VDIMSTFGHRNILSLKGAVLREGNSSPW-MVFEYMPYGDLAEVLRSNSRQFNRSPKPEMQ 312
Query: 788 PTAATLLH-IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
P LH I QIAAGM YL FVHRDLA RNCL+G + +KI+DFG + YTCDY
Sbjct: 313 PLTEESLHWITIQIAAGMTYLSGQRFVHRDLACRNCLVGYDFIVKIADFGMSRDVYTCDY 372
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
YK+ G LP+RW + ESV+ G++T +SDVW+F V L E+YS ++ Y H + E +
Sbjct: 373 YKIKGSRLLPIRWMSPESVMYGRFTLESDVWSFGVVLWEVYSFGKQPYYGH--NNEEVSK 430
Query: 907 LSHLQADDGMFECVDRAP--GCPRDLYELMLECWRRDELDRPTFGEI 951
+ L +F+ + P GCP + ++M ECW+ D DR F EI
Sbjct: 431 VVKL-----IFQGIMLIPPEGCPPFVCQIMRECWKTDPKDRIKFPEI 472
>UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 822
Score = 171 bits (417), Expect = 6e-41
Identities = 116/310 (37%), Positives = 167/310 (53%), Gaps = 42/310 (13%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKF---LCHDAT 732
T V RH + + +L EGAFG V++AE YN EK VAVK +
Sbjct: 512 TFVQHIKRHNIILKRELGEGAFGKVFLAEC-----YNLTPDQEKIHVAVKVGTGRFSPPS 566
Query: 733 LK----EREEFERDVRILAALSSPH------LARVLGAC-RSPPLAVVLEYLELGDLCAF 781
L ER + E+ +L +PH + G C S PL +V EY++ GDL F
Sbjct: 567 LPPSDPERSQREQPGGLLPGGRAPHQLQHEHIVTFYGVCVESDPLIMVFEYMKHGDLNKF 626
Query: 782 LRA-------------AIPP--TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGK 826
LR+ +IP T + +LHIA QIAAGM YL S +FVHRDLA RNCL+G+
Sbjct: 627 LRSHGPDAVLIVDGQHSIPVELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGE 686
Query: 827 GYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEI 886
+KI DFG + Y+ DYY+V G LP+RW ES++ ++TT+SDVW+ V L EI
Sbjct: 687 NLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRRFTTESDVWSLGVVLWEI 746
Query: 887 YSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRP 946
++ ++P+ L++ EV++ ++ + + R CP+++Y+LML CW R+ R
Sbjct: 747 FTY-GKQPWYQLSNNEVIECITQGRV-------LQRPRTCPKEVYDLMLGCWHREPYMRL 798
Query: 947 TFGEIHLFLQ 956
EI+ LQ
Sbjct: 799 NIKEIYGMLQ 808
>UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|Rep:
Bm-DAF-2 precursor - Brugia malayi (Filarial nematode
worm)
Length = 1456
Score = 171 bits (417), Expect = 6e-41
Identities = 99/284 (34%), Positives = 150/284 (52%), Gaps = 22/284 (7%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + + ++ G FG VY D Y G E A+K + A ER F
Sbjct: 1038 ELKRSAIHLEDEIGRGTFGKVYRGYGDNCKSYLGVTFGE---CAIKTVSETANSAERLHF 1094
Query: 740 ERDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLRAAIP----------- 787
+ ++ ++P + ++ G P+ VV+E ++ G+L +LR+ P
Sbjct: 1095 LIEASVMKQFNTPFIVKLYGVVSDGQPVLVVMEMMKKGNLRDYLRSRRPNAEENVNGLPV 1154
Query: 788 PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
P A A+Q+A GM YLESL F HRDLAARNC++ + +KI DFG + Y +YY
Sbjct: 1155 PGAIDFFRWASQVADGMAYLESLKFCHRDLAARNCMVNEFDTVKIGDFGMARDIYYHEYY 1214
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
K G+ +P+RW A ES++ GK+T KSDVW++ +TL+E+ +L ++PY L + V D +
Sbjct: 1215 KPAGKRLMPVRWMAPESLMDGKFTMKSDVWSYGITLYEMLTLA-QQPYLGLANESVFDYI 1273
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ + + R GCP YELM CW+ D +RPTF +I
Sbjct: 1274 GVKK------KILTRPTGCPDFWYELMKRCWKYDPRERPTFAQI 1311
>UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles sp.|Rep: Tyrosine-protein kinase receptor -
Anopheles sp
Length = 863
Score = 171 bits (417), Expect = 6e-41
Identities = 110/296 (37%), Positives = 168/296 (56%), Gaps = 30/296 (10%)
Query: 682 PRHRLRMI-----SKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER 736
PR RL I S L GAFG VY GV +G +E R VA+K L A L E+
Sbjct: 442 PRIRLDQIFMASSSLLGSGAFGEVYEGVVKGV---DGE--AETR-VAIKTLKKGAKLHEK 495
Query: 737 EEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA-IPPTAATL- 793
+EF ++ ++++ H+ R+LG C + L +++E ++ GDL ++L A +P AA L
Sbjct: 496 QEFLQEAQLMSNFKHKHITRLLGVCLEADALLIIMELMQGGDLLSYLPAQPLPGQAARLT 555
Query: 794 ----LHIATQIAAGMQYLESLNFVHRDLAARNCLIG----KGYQIKISDFGTDNEAYTCD 845
+ + +A+G +YLE ++FVHRDLA RNCL+ + +KI DFG + Y D
Sbjct: 556 MLDLISMCQDVASGCRYLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKND 615
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
YY+ +G LP+RW + ES++ G +T++SD+WAF V L EI +L +PY+ + EVL+
Sbjct: 616 YYRKEGEGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTL-GEQPYQAKNNVEVLN 674
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLN 961
++ + G +DR CP ++YELM CW+ +RPTF L+R+ N
Sbjct: 675 HV----REGGH---LDRPKVCPNEMYELMKYCWKFSPEERPTFRYCLEVLERRCQN 723
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 171 bits (417), Expect = 6e-41
Identities = 104/276 (37%), Positives = 149/276 (53%), Gaps = 24/276 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY G VAVK L D E EEF
Sbjct: 122 EMERTDITMKHKLGGGQYGEVY----------EGVWKKYSLTVAVKTLKEDTM--EVEEF 169
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--TAATLLHI 796
++ ++ + P+L ++LG C R PP ++ E++ G+L +LR +A LL++
Sbjct: 170 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYM 229
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQI++ M+YLE NF+HRDLAARNCL+G+ + +K++DFG + T D Y P
Sbjct: 230 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL-SRLMTGDTYTAHAGAKFP 288
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A ES+ K++ KSDVWAF V L EI + PY + +V + L+ D M
Sbjct: 289 IKWTAPESLAYNKFSIKSDVWAFGVLLWEI-ATYGMSPYPGIDLSQVYE---LLEKDYRM 344
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+R GCP +YELM CW+ + DRP+F EIH
Sbjct: 345 ----ERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 376
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 171 bits (416), Expect = 8e-41
Identities = 104/276 (37%), Positives = 148/276 (53%), Gaps = 24/276 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY G VAVK L D E EEF
Sbjct: 236 EMERTDITMKHKLGGGQYGEVY----------EGVWKKYSLTVAVKTLKEDTM--EVEEF 283
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--TAATLLHI 796
++ ++ + P+L ++LG C R PP ++ E++ G+L +LR A LL++
Sbjct: 284 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYM 343
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQI++ M+YLE NF+HRDLAARNCL+G+ + +K++DFG + T D Y P
Sbjct: 344 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL-SRLMTGDTYTAHAGAKFP 402
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A ES+ K++ KSDVWAF V L EI + PY + +V + L+ D M
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEI-ATYGMSPYPGIDLSQVYE---LLEKDYRM 458
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+R GCP +YELM CW+ + DRP+F EIH
Sbjct: 459 ----ERPEGCPEKVYELMRACWQWNPSDRPSFAEIH 490
>UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles gambiae str. PEST|Rep: Tyrosine-protein kinase
receptor - Anopheles gambiae str. PEST
Length = 2075
Score = 171 bits (415), Expect = 1e-40
Identities = 107/284 (37%), Positives = 164/284 (57%), Gaps = 31/284 (10%)
Query: 682 PRHRLRMI-----SKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER 736
PR RL I S L GAFG VY GV +G +E R VA+K L A L E+
Sbjct: 1796 PRIRLDQIFMASSSLLGSGAFGEVYEGVVKGV---DGE--AETR-VAIKTLKKGAKLHEK 1849
Query: 737 EEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA--IPPTAATL 793
+EF ++ ++++ H+ R+LG C + L +++E ++ GDL ++LR + +P AA L
Sbjct: 1850 QEFLQEAQLMSNFKHKHITRLLGVCLEADALLIIMELMQGGDLLSYLRRSRSLPGQAARL 1909
Query: 794 -----LHIATQIAAGMQYLESLNFVHRDLAARNCLIG----KGYQIKISDFGTDNEAYTC 844
+ + +A+G +YLE ++FVHRDLA RNCL+ + +KI DFG + Y
Sbjct: 1910 TMLDLISMCQDVASGCRYLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYKN 1969
Query: 845 DYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVL 904
DYY+ +G LP+RW + ES++ G +T++SD+WAF V L EI +L +PY+ + EVL
Sbjct: 1970 DYYRKEGEGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTL-GEQPYQAKNNVEVL 2028
Query: 905 DNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+++ + G +DR CP ++YELM CW+ +RPTF
Sbjct: 2029 NHV----REGGH---LDRPKVCPNEMYELMKYCWKFSPEERPTF 2065
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 171 bits (415), Expect = 1e-40
Identities = 104/276 (37%), Positives = 147/276 (53%), Gaps = 24/276 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY G VAVK L D E EEF
Sbjct: 185 EMERTDITMKHKLGGGQYGEVY----------EGVWKKYSLTVAVKTLKEDTM--EVEEF 232
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--TAATLLHI 796
++ ++ + P+L ++LG C R PP ++ E++ G+L +LR A LL++
Sbjct: 233 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYM 292
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQI++ M+YLE NF+HRDLAARNCL+G+ + +K++DFG + T D Y P
Sbjct: 293 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGL-SRLMTGDTYTAHAGTKFP 351
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A ES+ K++ KSDVWAF V L EI + PY + +V + L+ D M
Sbjct: 352 IKWTAPESLAYNKFSIKSDVWAFGVLLWEI-ATYGMSPYPGIDLSQVYE---LLEKDYRM 407
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+R GCP +YELM CW+ + DRP F EIH
Sbjct: 408 ----ERPEGCPEKVYELMRACWQWNPSDRPAFAEIH 439
>UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin
receptor; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to insulin receptor - Tribolium castaneum
Length = 1351
Score = 170 bits (414), Expect = 1e-40
Identities = 108/299 (36%), Positives = 160/299 (53%), Gaps = 29/299 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ +I +L +G+FG VY A V G + AVK + AT +ER EF
Sbjct: 974 EVPRKKIELIRELGQGSFGMVYEGIAQDV---RGKAQIK---CAVKTVNEHATNRERLEF 1027
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR-------------AA 785
+ ++ A + H+ R+LG + P V++E + GDL +LR A
Sbjct: 1028 LNEASVMKAFDTAHVVRLLGVVSQGQPTLVIMELMANGDLKTYLRSHRPDAEVYDPATAK 1087
Query: 786 IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD 845
PPT +L +A +IA GM YL + FVHRDLAARNC++ + +KI DFG + Y D
Sbjct: 1088 QPPTLKQILQMAIEIADGMAYLSAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETD 1147
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
YY+ + LP+RW A ES+ G +T+ SDVW++ V L E+ +L +PY+ L++ +VL
Sbjct: 1148 YYRKGTKGLLPVRWMAPESLKDGVFTSNSDVWSYGVVLWEMATLA-SQPYQGLSNDQVL- 1205
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI-HLFLQRKSLNYA 963
D G+ E R CP LY LM CW+ RP+F ++ L L+ S ++A
Sbjct: 1206 ---RYVIDGGVME---RPENCPDKLYTLMRYCWQHKPSARPSFLKLCSLLLEDASTSFA 1258
>UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 948
Score = 170 bits (413), Expect = 2e-40
Identities = 100/304 (32%), Positives = 167/304 (54%), Gaps = 32/304 (10%)
Query: 673 LETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDAT 732
L+ T + E R ++R L +G FG V A A GV ++ +VAVK L A+
Sbjct: 604 LDGTPLPEVDRDKVRYEGDLGQGHFGLVVKATALGVVPGR-----DQCIVAVKILKEGAS 658
Query: 733 LKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--- 788
L+ ++EF + ++ + P++ +++G C PL ++ E+++LGDL FLR P
Sbjct: 659 LQTKKEFFHEAALMHSFDHPNIVKLIGVCVEQEPLCMIFEFMQLGDLNNFLRHNSPKWQE 718
Query: 789 ---------------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKIS 833
T + ++ I AG+ YL +++HRDLA RNCL+ +IKIS
Sbjct: 719 SSASCAKYGGPKCDITTPIQVAMSLDITAGLAYLADNHYIHRDLATRNCLVSGDLRIKIS 778
Query: 834 DFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR 893
DFG + Y+ DY ++ LP+RW E++L ++TT+SDVW+ V L E++S +
Sbjct: 779 DFGLSQDIYSTDYCRLSQSELLPIRWMPPEAILFARFTTQSDVWSLGVVLWELFSY-GIQ 837
Query: 894 PYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHL 953
PY +++ +V ++H++ D + C D GCP ++Y+LM++CW D RPT ++++
Sbjct: 838 PYYSMSNEQV---IAHVR-DGNVMNCPD---GCPSEIYDLMVDCWNMDPGQRPTAADVNV 890
Query: 954 FLQR 957
LQR
Sbjct: 891 ALQR 894
>UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; Aedes
aegypti|Rep: Tyrosine-protein kinase receptor - Aedes
aegypti (Yellowfever mosquito)
Length = 2073
Score = 170 bits (413), Expect = 2e-40
Identities = 107/280 (38%), Positives = 158/280 (56%), Gaps = 28/280 (10%)
Query: 683 RHRLRMISK--LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
R ++ M S L GAFG VY GV G +E R VA+K L AT +E+ EF
Sbjct: 1807 REQISMTSSPFLGSGAFGEVYEGIVKGV----GG-EAETR-VAIKTLRKGATEQEKAEFL 1860
Query: 741 RDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLRAAIP----PTAATLLH 795
++ +++ H+ +++G C L +V+E ++ GDL ++LR+ P P+ TLL
Sbjct: 1861 QEAHLMSNFKHKHILKLIGVCLDLDSLYIVMELMQGGDLLSYLRSNRPTPGNPSMLTLLD 1920
Query: 796 IATQ---IAAGMQYLESLNFVHRDLAARNCLIG----KGYQIKISDFGTDNEAYTCDYYK 848
+ + +A G +YLE ++FVHRDLA RNCL+ + +KI DFG + Y DYY+
Sbjct: 1921 LISMCVDVATGCRYLEEMHFVHRDLACRNCLVSSMDPRERVVKIGDFGLARDIYKNDYYR 1980
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
+G LP+RW + ES++ G +T++SD+WAF V L EI +L ++PY + EVL
Sbjct: 1981 KEGEGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTL-GQQPYPARNNVEVL---- 2035
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
H D G + R CP +LY+LML+CW DRPTF
Sbjct: 2036 HYVRDGGR---LTRPQDCPEELYQLMLKCWSYSPEDRPTF 2072
>UniRef50_P42159 Cluster: Class II receptor tyrosine kinase; n=5;
Geodia cydonium|Rep: Class II receptor tyrosine kinase -
Geodia cydonium (Sponge)
Length = 605
Score = 170 bits (413), Expect = 2e-40
Identities = 95/243 (39%), Positives = 145/243 (59%), Gaps = 25/243 (10%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEK--------RLVAVKFLCHDATLKERE 737
+R + ++ G FG V +AE G+ + +++ LVAVK L D + + R+
Sbjct: 346 IREVKQIGVGQFGAVVLAEMTGLSGSERCVPTKRDPSMLNGVALVAVKKLKPDVSEEVRQ 405
Query: 738 EFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA------------ 784
F+++++ ++ L + ++L C S +V+EY+E GDL FL+
Sbjct: 406 SFDKEIKFVSQLQHDSIVQLLAVCTHSKHPFIVMEYMENGDLNQFLQKYQMVDDDSALYS 465
Query: 785 -AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
IPP+ TLL++A QIA+GM YL SLN+VHRDLA RNCL+G ++IKISDFG Y
Sbjct: 466 NQIPPS--TLLYMAVQIASGMVYLSSLNYVHRDLATRNCLVGSNFRIKISDFGMSRNLYE 523
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
YY+V GR LP+RW A ES G+++ KSD WA+ VT+ EIY+L +++PYE L D ++
Sbjct: 524 RVYYRVRGRAMLPIRWMATES-FYGRFSEKSDAWAYGVTVWEIYTLGKKQPYEELDDQDM 582
Query: 904 LDN 906
+ +
Sbjct: 583 IQD 585
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 169 bits (411), Expect = 3e-40
Identities = 106/280 (37%), Positives = 148/280 (52%), Gaps = 24/280 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY A YN VAVK L D + +F
Sbjct: 283 EINRTDIVMRHKLGGGQYGDVYEAVWK---RYN-------MTVAVKTLKEDTMALK--DF 330
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR--AAIPPTAATLLHI 796
+ I+ + +L ++LG C R PP ++ E++ G+L +LR + A L+H+
Sbjct: 331 LEEAAIMKEMKHRNLVQLLGVCTREPPFYIITEFMSKGNLLDYLRNESKHQINAVVLMHM 390
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQIA+GM YLES NF+HRDLAARNCL+G+ + +K++DFG D Y P
Sbjct: 391 ATQIASGMSYLESRNFIHRDLAARNCLVGENHLVKVADFGL-ARLMRDDTYTAHAGAKFP 449
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A E + K++TKSDVWAF + L EI + PY + L ++ H+
Sbjct: 450 IKWTAPEGLAYNKFSTKSDVWAFGILLWEI-ATYGMSPYPGVD----LTDVYHMLEKGYR 504
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EC PGCP +YELM +CW+ DRPTF EIH L+
Sbjct: 505 MEC---PPGCPPKVYELMRQCWQWSAADRPTFKEIHHSLE 541
>UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2;
Strongylocentrotus purpuratus|Rep: Tyrosine-protein
kinase receptor - Strongylocentrotus purpuratus (Purple
sea urchin)
Length = 1072
Score = 169 bits (411), Expect = 3e-40
Identities = 105/289 (36%), Positives = 163/289 (56%), Gaps = 26/289 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGV-PEYNGAITSEKRLVAVKFLCHDATLKEREE 738
EFPR +L +I +L +G+FG VY A G+ PE E VA+K + +A++++R E
Sbjct: 693 EFPRDKLEIIRELGKGSFGMVYEGLAKGILPE-----EEEISRVAIKSVQANASMRDRIE 747
Query: 739 FERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP---------P 788
F + ++ + + ++ R+LG + P V++E++ GDL +LRA P P
Sbjct: 748 FLNEASVMKLIDAHNVVRLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPENQQDLPSVP 807
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
T LL++A +IA GM +L + +VHRDL+ARNCL+ K++DFG + Y DYY+
Sbjct: 808 TLEQLLNMAAEIADGMSFLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQSDYYR 867
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
+ LP+RW A ESV G + SDVW+F + L E+ +L PY+ L++ E +
Sbjct: 868 KERGGMLPIRWMAPESVKDGVFQASSDVWSFGILLWEMATL-GELPYQGLSNEEAGE--- 923
Query: 909 HLQADDGMFECVDRAP-GCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+++ + V R P CP + E+M+ CW+ E RP FGEI L LQ
Sbjct: 924 YIKGGN-----VLRPPENCPEKMQEIMMACWQYQEKLRPLFGEIILNLQ 967
>UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1;
Crassostrea gigas|Rep: Tyrosine-protein kinase receptor
- Crassostrea gigas (Pacific oyster) (Crassostrea
angulata)
Length = 804
Score = 169 bits (410), Expect = 4e-40
Identities = 106/293 (36%), Positives = 157/293 (53%), Gaps = 34/293 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++++I +L +G+FG VY A + G I VAVK + AT +ER EF
Sbjct: 329 EVERDKIQLIRELGQGSFGMVYEGVARDLYGKGGEIK-----VAVKTVNEHATYRERMEF 383
Query: 740 ERDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLR--------------- 783
+ + A S H+ R+LG P +++E +E GDL FLR
Sbjct: 384 LSEASRMKAFSCNHVVRLLGVVSDGQPALLIMELMEKGDLKNFLRMHRPVEEDIDSTFAG 443
Query: 784 -----AAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
+ PPT ++ +A +IA GM YL FVHRDLAARNC++ + +KI+DFG
Sbjct: 444 IKEHISRTPPTIKRIIQMAGEIADGMAYLADKKFVHRDLAARNCMVAEDLTVKIADFGMT 503
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
+ Y DYY+ G+ LP+RW A ES+ G +T+ SDVW++ V L E+ +L +PY+ L
Sbjct: 504 RDIYETDYYRKGGKALLPVRWMAPESLKDGIFTSLSDVWSYGVVLWEMATLA-AQPYQGL 562
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ EVL + + + +++ CP L+ELM +CWR RPTF EI
Sbjct: 563 SNEEVLRYVLNGRV-------MEKPEDCPDRLFELMQKCWRYRPKQRPTFKEI 608
>UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1;
Ciona intestinalis|Rep: Tyrosine-protein kinase receptor
- Ciona intestinalis (Transparent sea squirt)
Length = 465
Score = 168 bits (409), Expect = 5e-40
Identities = 100/282 (35%), Positives = 149/282 (52%), Gaps = 23/282 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E P + ++ ++ G FG VY A V + K VAVK L + ++ +R EF
Sbjct: 93 EIPEENVELMDEIGHGHFGKVYEGLAKQVVK-----GQPKTKVAVKTLHGNESISKRMEF 147
Query: 740 ERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIP---------PT 789
++ ++ A +S H+ R+LG S V++E++ GDL +LR+ P P+
Sbjct: 148 LKEASVMKAFNSHHVVRLLGVVSMSKRPMVIMEFMAKGDLKTYLRSTRPDAEIRKGDPPS 207
Query: 790 AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV 849
L + +IA GM YL +VHRDLAARNCL+ + +KI DFG + Y DYY++
Sbjct: 208 LQQKLQMCGEIADGMSYLSETKYVHRDLAARNCLVHEDLTVKIGDFGLTRDVYETDYYRI 267
Query: 850 DGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSH 909
D R LP+RW A ES+ G + ++SDVW+F + L EI +L +PY+ + D ++
Sbjct: 268 DSRGILPVRWMAPESLKDGVFDSRSDVWSFGIVLWEIATLA-EQPYQG----QQHDQVTR 322
Query: 910 LQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G E + CP LY++ML CW RPTF EI
Sbjct: 323 FVIDGGYME---QPKECPSKLYDMMLMCWHYSPSMRPTFLEI 361
>UniRef50_Q25410 Cluster: Putative molluscan insulin-related
peptide(s) receptor precursor (EC 2.7.10.1) [Contains:
Putative molluscan insulin-related peptide(s) receptor
alpha chain; Putative molluscan insulin-related
peptide(s) receptor beta chain]; n=2; Coelomata|Rep:
Putative molluscan insulin-related peptide(s) receptor
precursor (EC 2.7.10.1) [Contains: Putative molluscan
insulin-related peptide(s) receptor alpha chain; Putative
molluscan insulin-related peptide(s) receptor beta chain]
- Lymnaea stagnalis (Great pond snail)
Length = 1607
Score = 168 bits (409), Expect = 5e-40
Identities = 100/289 (34%), Positives = 157/289 (54%), Gaps = 22/289 (7%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++++I +L +G+FG VY A G+ + +E+ VAVK + A+ +R EF
Sbjct: 1031 EVDRDKIKLIKELGQGSFGMVYEGVAKGIRDD----PNEEIPVAVKTVNDRASFSDRREF 1086
Query: 740 ERDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLRA---------AIPPT 789
++ + H+ ++LG + P V++E + LGDL +LR +PP
Sbjct: 1087 LKEATTMKEFHCHHVVKLLGVVSTGQPALVIMELMALGDLKNYLRGHRPDEDHPGVMPPH 1146
Query: 790 AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV 849
+L +A +IA GM YL FVHRDLAARNC++ + +KI DFG + Y DYY+
Sbjct: 1147 LLDILQMAGEIADGMAYLADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYETDYYRK 1206
Query: 850 DGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSH 909
G+ LP+RW A ES+ G +T+ SDVW++ V + E+ +L +PY+ L++ EV+ +S
Sbjct: 1207 GGKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLA-AQPYQGLSNEEVVKFIS- 1264
Query: 910 LQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRK 958
DG ++ CP ++ LM CW + RPTF I +L K
Sbjct: 1265 ----DGYI--MELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYLLPK 1307
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 168 bits (409), Expect = 5e-40
Identities = 104/276 (37%), Positives = 146/276 (52%), Gaps = 24/276 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VYV G VAVK L D E EEF
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYV----------GVWKKYSLTVAVKTLKEDTM--EVEEF 329
Query: 740 ERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPP--TAATLLHI 796
++ ++ + P+L ++LG C PP +V EY+ G+L +LR TA LL++
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYM 389
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQI++ M+YLE NF+HRDLAARNCL+G+ + +K++DFG + T D Y P
Sbjct: 390 ATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGL-SRLMTGDTYTAHAGAKFP 448
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A ES+ ++ KSDVWAF V L EI + PY + +V D L + G
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEI-ATYGMSPYPGIDLSQVYDLL-----EKGY 502
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
+++ GCP +YELM CW+ DRP+F E H
Sbjct: 503 --RMEQPEGCPPKVYELMRACWKWSPADRPSFAETH 536
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 168 bits (408), Expect = 7e-40
Identities = 105/280 (37%), Positives = 148/280 (52%), Gaps = 24/280 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M KL G +G VY A YN VAVK L D + +F
Sbjct: 284 EINRTDIVMRHKLGGGQYGDVYEAVWK---RYN-------MTVAVKTLKEDTMALK--DF 331
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR--AAIPPTAATLLHI 796
+ I+ + +L +++G C R PP ++ E++ G+L +LR + A L+H+
Sbjct: 332 LEEAAIMKEMKHRNLVQLIGVCTREPPFYIITEFMSKGNLLDYLRNESKHQINAVVLMHM 391
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
ATQIA+GM YLES NF+HRDLAARNCL+G+ + +K++DFG D Y P
Sbjct: 392 ATQIASGMSYLESRNFIHRDLAARNCLVGESHLVKVADFGL-ARLMRDDTYTAHAGAKFP 450
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A E + K++TKSDVWAF + L EI + PY + L ++ H+
Sbjct: 451 IKWTAPEGLAYNKFSTKSDVWAFGILLWEI-ATYGMSPYPGVD----LTDVYHMLEKGYR 505
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EC PGCP +YELM +CW+ DRPTF EIH L+
Sbjct: 506 MEC---PPGCPPKVYELMRQCWQWSASDRPTFKEIHHSLE 542
>UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ROS
precursor; n=20; Eumetazoa|Rep: Proto-oncogene
tyrosine-protein kinase ROS precursor - Homo sapiens
(Human)
Length = 2347
Score = 167 bits (407), Expect = 1e-39
Identities = 108/296 (36%), Positives = 162/296 (54%), Gaps = 25/296 (8%)
Query: 674 ETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATL 733
E N+ FPR +L + L GAFG VY A + + S + VAVK L +T
Sbjct: 1933 EIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDIL----GVGSGEIKVAVKTLKKGSTD 1988
Query: 734 KEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAA-----IP 787
+E+ EF ++ +++ + P++ + LG C + P ++LE +E GDL +LR A
Sbjct: 1989 QEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYG 2048
Query: 788 P--TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIG-KGYQ----IKISDFGTDNE 840
P T L+ + I+ G YLE ++F+HRDLAARNCL+ K Y +KI DFG +
Sbjct: 2049 PLLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARD 2108
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
Y DYY+ G LP+RW A ES++ G +TT+SDVW+F + + EI +L +PY ++
Sbjct: 2109 IYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTL-GHQPYPAHSN 2167
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
LD L+++Q + + CP DL+ LM +CW ++ RPTF I LQ
Sbjct: 2168 ---LDVLNYVQTGGRL----EPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQ 2216
>UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-like
growth factor 1 receptor precursor (Insulin-like growth
factor I receptor) (IGF-I receptor); n=1; Apis
mellifera|Rep: PREDICTED: similar to Insulin-like growth
factor 1 receptor precursor (Insulin-like growth factor
I receptor) (IGF-I receptor) - Apis mellifera
Length = 855
Score = 167 bits (406), Expect = 1e-39
Identities = 102/281 (36%), Positives = 150/281 (53%), Gaps = 22/281 (7%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ M+ L G FG VY A + + SE R AVK + DAT +ER EF
Sbjct: 324 EVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGK----SEVRC-AVKTVNKDATDRERIEF 378
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA--------IPPTA 790
+ ++ + H+ ++LG R P V++E + GDL +LR+ PP
Sbjct: 379 LNEASVMKGFDAHHVVKLLGVVTRGQPTLVIMELMVNGDLKRYLRSHRPCENMSNAPPKL 438
Query: 791 ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVD 850
+L +A +IA GM YL + FVHRDLAARNC++ + +K+ DFG + Y DYY+
Sbjct: 439 DRILQMAIEIADGMAYLSTKKFVHRDLAARNCMVAEDLTVKVGDFGMTRDIYERDYYRKG 498
Query: 851 GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHL 910
+ LP+RW A ES+ G +++ SDVW++ V L E+ + +PY+ L++ +VL
Sbjct: 499 SKGLLPVRWMAPESLKDGVFSSYSDVWSYGVVLWEMVTFA-SQPYQGLSNEQVL----RY 553
Query: 911 QADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G+ E R CP LYELM WR RPTF +I
Sbjct: 554 VIEGGVME---RPENCPELLYELMKRTWRHKATRRPTFMDI 591
>UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690;
n=3; Danio rerio|Rep: hypothetical protein LOC553690 -
Danio rerio
Length = 981
Score = 167 bits (405), Expect = 2e-39
Identities = 108/322 (33%), Positives = 168/322 (52%), Gaps = 32/322 (9%)
Query: 647 LNPSVRSKQSTRSPSQQEILL-------DLKRRLETTNVIEFPRHRLRMISKLAEGAFGT 699
LN V+ T + Q+E+ L + KR + ++FPR L I+ L +G FG
Sbjct: 662 LNGEVQQNGHTTAEIQEEVALTNMAAAGNNKRHSSHESKLQFPRSNLHTITTLGKGEFGE 721
Query: 700 VYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLG 759
V +A+A + E+ +V VK L + + +F R+ + A LS ++AR+LG
Sbjct: 722 VLLAKAKAAED------EEETVVLVKSL-QTRDEQMQMDFRRECDMFAKLSHSNVARLLG 774
Query: 760 ACRS-PPLAVVLEYLELGDLCAFLRAAI---------PPTAATLLHIATQIAAGMQYLES 809
CR P +++EY ++GDL +LR + P + + + Q+A GM++L +
Sbjct: 775 ICREVEPHYMIMEYTDMGDLKQYLRVSKSKDEKVKVQPLSTKQKVSVCLQVARGMEHLSN 834
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGK 869
FVH+DLAARNCLI QIK+S G + Y+ +YY + +PLRW E+V
Sbjct: 835 QRFVHKDLAARNCLISSKRQIKVSSLGLSKDVYSSEYYHY-RQSYIPLRWLPSEAVFEDD 893
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRD 929
++TK+DVW+FAV + E++S PY L D +VL+ L DG + GCP
Sbjct: 894 FSTKTDVWSFAVLMWEVFSF-GEMPYADLADDKVLEAL-----QDGKLKLCP-PQGCPSR 946
Query: 930 LYELMLECWRRDELDRPTFGEI 951
+++LM+ CW DR +F EI
Sbjct: 947 VFKLMVRCWAASPKDRLSFSEI 968
>UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR1 precursor; n=21; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR1
precursor - Homo sapiens (Human)
Length = 937
Score = 166 bits (403), Expect = 3e-39
Identities = 105/295 (35%), Positives = 158/295 (53%), Gaps = 32/295 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E P +R + +L E AFG +Y +P + A +LVA+K L ++ EF
Sbjct: 467 ELPLSAVRFMEELGECAFGKIYKGHLY-LPGMDHA-----QLVAIKTLKDYNNPQQWTEF 520
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAA------- 791
+++ ++A L P++ +LGA + P+ ++ EY+ GDL FL P +
Sbjct: 521 QQEASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDED 580
Query: 792 ----------TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
LHIA QIAAGM+YL S FVH+DLAARN LIG+ +KISD G E
Sbjct: 581 GTVKSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREI 640
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
Y+ DYY+V + LP+RW E+++ GK+++ SD+W+F V L EI+S +PY ++
Sbjct: 641 YSADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSF-GLQPYYGFSNQ 699
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
EV++ + Q + C + CP +Y LM ECW RP F +IH+ L+
Sbjct: 700 EVIEMVRKRQ----LLPC---SEDCPPRMYSLMTECWNEIPSRRPRFKDIHVRLR 747
>UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to RE05926p, partial -
Strongylocentrotus purpuratus
Length = 859
Score = 165 bits (402), Expect = 4e-39
Identities = 103/298 (34%), Positives = 159/298 (53%), Gaps = 35/298 (11%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+EFPR+RL + +KL G+F VY AEA G+ EK +VAVK L AT ++ +
Sbjct: 306 MEFPRNRLTLFNKLGSGSFADVYKAEAVGI-----ITKEEKTIVAVKRLKETATENDKSD 360
Query: 739 FERDVRILAALSS-PHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAA----------- 785
+++ + L P++ +LG C S P +++EYL +L +LR
Sbjct: 361 LSKELSLYMYLDPHPNIVNILGCCTDSDPWYIIMEYLPNNNLQGYLRQIRTGESMTADYR 420
Query: 786 -------IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
IPP LL QIA GM+YL S +HRDLAARN L+G+GY K+SDFG
Sbjct: 421 NVKKQKDIPPN--DLLTFGVQIARGMEYLASRQCIHRDLAARNILLGEGYVCKVSDFGLA 478
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
+ Y++ + +P+RW + ES+L YT++SDVW+FA+ + EI +L PY +
Sbjct: 479 RDLEDGQTYEMKSQGRVPVRWMSPESLLHNTYTSQSDVWSFAILIWEIVTL-GSHPYPGM 537
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ +V+ +S + + C +D+Y LM ECW + +RPTF ++ + L+
Sbjct: 538 SSKQVVKEISAGYR-------LPKPEHCSQDIYNLMKECWAYEAEERPTFSQVKVRLE 588
Score = 57.2 bits (132), Expect = 2e-06
Identities = 37/115 (32%), Positives = 62/115 (53%), Gaps = 13/115 (11%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSE-KRLVAVKFLCHDATLKERE 737
+EFPR+RL +++KL G+F VY AEA G+ IT E K +VAVK L AT ++
Sbjct: 131 MEFPRNRLTLLNKLGSGSFADVYKAEALGI------ITKEQKTIVAVKRLKDTATENDKS 184
Query: 738 EFERDVRILAALS-SPHLARVLGAC-----RSPPLAVVLEYLELGDLCAFLRAAI 786
+ +++ + L P++ +LG C ++PP+ L +G + + A +
Sbjct: 185 DLSKELSLYMYLDPHPNIVNILGCCTDADTQNPPMNNALSQTTIGIIAGSVAAVV 239
>UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7099, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1000
Score = 165 bits (402), Expect = 4e-39
Identities = 113/345 (32%), Positives = 168/345 (48%), Gaps = 62/345 (17%)
Query: 659 SPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSE 718
+P Q + L L +L +E+PR+ ++ + + EGAFG V+ A A G+
Sbjct: 670 NPMYQRVPLLLNSKLLA---LEYPRNNIQYVRDIGEGAFGRVFQARAPGLLPMESFT--- 723
Query: 719 KRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGA------------CRSP-- 764
+VAVK L +A+ + +F+R+ ++A P++ ++LGA C P
Sbjct: 724 --MVAVKMLKEEASADMQNDFQREAALMAQFDHPNIVKLLGASFQAVNYGCGCACVCPLT 781
Query: 765 -------PLAVVLEYLELGDLCAFLRAAIPP-------------------------TAAT 792
P+ ++ EY+ GDL FLR P + A
Sbjct: 782 GVCAVGKPMCLMFEYMAHGDLNEFLRRRSPDQSVRTISRASLSGRSFTSELEAGLLSCAD 841
Query: 793 LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 852
L I+ QIAAGM YL FVHRDLA RNCL+G+ +KI+DFG Y+ DYYK +
Sbjct: 842 QLSISKQIAAGMAYLSERKFVHRDLATRNCLVGEEMVVKIADFGLSRNIYSADYYKANEN 901
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
+P+RW ES+ +YTT+SD+WA+ V L EI+S +PY + EV+ +
Sbjct: 902 DAIPIRWMPPESIFYNRYTTESDIWAYGVVLWEIFS-HGMQPYYGMGHEEVI----YYVR 956
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
D + C + CP +LY LM CW +RP+F IH L+R
Sbjct: 957 DGHILSCPE---NCPLELYNLMRLCWSSQPPERPSFSSIHRILER 998
>UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 2069
Score = 165 bits (402), Expect = 4e-39
Identities = 102/283 (36%), Positives = 160/283 (56%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEA-DGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+FPR L++ + + G FG V+ A D + G I VAVK L A ++E+++
Sbjct: 1696 KFPRGNLKLENFIDRGEFGEVFQGTATDILGPGTGPIP-----VAVKTLRKGAIIEEQKK 1750
Query: 739 FERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAI----PP--TAA 791
F + ++ + P++ +VLG C + P+ +++E + GDL FLR A PP T
Sbjct: 1751 FLAEAALMGNFNHPNIVKVLGVCVENDPVYIIMELMPGGDLLHFLRDAKVERGPPLLTVK 1810
Query: 792 TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIG-KGYQ--IKISDFGTDNEAYTCDYYK 848
L+ IA +A G YL+ +F+HRDLAARNCL+ KG +KI DFG + Y+ DYY+
Sbjct: 1811 ELIQIALDVAQGCHYLQQTHFIHRDLAARNCLVSSKGADRVVKIGDFGLAKDLYSSDYYQ 1870
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
V+G+ LP+RW A E++L+GK+ +SDVW+F V + EI + +PY L + EVL ++
Sbjct: 1871 VEGQRKLPVRWMAPEALLQGKFNMESDVWSFGVLMWEIMTF-GNQPYPALNNQEVLQFVT 1929
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+G + + CP +Y+LM CW++ +R F I
Sbjct: 1930 ----AEGRLQ---KPENCPGKIYQLMQNCWKKVASERLHFDVI 1965
>UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;
Aplysia californica|Rep: Trk-like receptor tyrosine
kinase - Aplysia californica (California sea hare)
Length = 865
Score = 165 bits (401), Expect = 5e-39
Identities = 116/309 (37%), Positives = 159/309 (51%), Gaps = 37/309 (11%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKERE 737
V E P L +I + EGAFG V+ E GA VAVK L A+ E
Sbjct: 287 VQEVPADCLTLIEVVGEGAFGQVFRGELRSAE--GGACHQ----VAVKVLKDGASPDAHE 340
Query: 738 EFERDVRILAALSSPHLARVLG----ACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT- 792
+FER+V I++A ++ ++LG P +V EY+E GDL LR P +
Sbjct: 341 DFEREVEIMSAFDHDNILKLLGIVVQGVEGAPY-MVFEYMEHGDLSELLRRNDPHLRSAD 399
Query: 793 ----------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGK-----GYQIKISDFGT 837
L+ I+ QIA GM+YL + FVHRDLA RNCL+G G +KISDFG
Sbjct: 400 SKTFRLNKSDLVEISVQIATGMRYLAAQRFVHRDLATRNCLVGTAPPGAGLLVKISDFGM 459
Query: 838 DNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
+ YT DYYK+ G LP+RW + E++ G++T +SDVWA+ V L EI+S R+PY
Sbjct: 460 SRDIYTNDYYKIGGSRMLPIRWMSPEAIKYGRFTCESDVWAYGVVLWEIFSY-GRQPYFG 518
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL-- 955
++ EV+ L D G+ + R CP +Y +ML CW+ D R F + +L
Sbjct: 519 HSNEEVIHFL-----DQGIL--LQRPEDCPSTVYHVMLGCWKGDPRQRIVFDRLLKYLTD 571
Query: 956 QRKSLNYAT 964
R LN T
Sbjct: 572 YRDRLNKPT 580
>UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK splice
variant A; n=9; Diptera|Rep: Receptor protein tyrosine
kinase ALK splice variant A - Drosophila melanogaster
(Fruit fly)
Length = 1701
Score = 164 bits (398), Expect = 1e-38
Identities = 102/291 (35%), Positives = 158/291 (54%), Gaps = 24/291 (8%)
Query: 669 LKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLC 728
L ++ ++ + R L++++ L +GAFG VY+A + + E VAVK L
Sbjct: 1176 LNGHIDVNSLPQVARDSLQLVNALGKGAFGEVYMA----LYRHRDGDAVEMG-VAVKTLR 1230
Query: 729 HDATLKEREEFERDVRILAALSSPHLARVLGACRS-PPLAVVLEYLELGDLCAFLRAA-- 785
D ++ E+F ++ I+A + P++ ++G C P +VLE L GDL FLR
Sbjct: 1231 EDPKREKEEDFLKEAAIMAKFNHPNMVHLIGVCFDRQPYYIVLELLAGGDLQKFLRENRN 1290
Query: 786 IP--PTAAT---LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGT 837
P P+ T LL A +A G +Y+ES F+HRD+AARNCL+ G G +KI+DFG
Sbjct: 1291 TPERPSLLTMKDLLFCALDVAKGCRYMESKRFIHRDIAARNCLLSSKGPGRVVKIADFGM 1350
Query: 838 DNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
+ Y DYY+ G+ LP++W E+ L G +T+K+DVW+F + L E++SL R PY
Sbjct: 1351 SRDIYRSDYYRKGGKAMLPIKWMPPEAFLDGIFTSKTDVWSFGILLWEVFSL-GRSPYPG 1409
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ +V++ L G + CP +Y++M +CW DRPTF
Sbjct: 1410 QHNTQVME----LVVRGGR---LGSPTECPVSIYKVMADCWNPTPEDRPTF 1453
>UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-oncogene
c-ros-1 protein precursor; n=1; Apis mellifera|Rep:
PREDICTED: similar to proto-oncogene c-ros-1 protein
precursor - Apis mellifera
Length = 2105
Score = 163 bits (396), Expect = 2e-38
Identities = 109/280 (38%), Positives = 160/280 (57%), Gaps = 30/280 (10%)
Query: 683 RHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERD 742
R ++ + L GAFG V+ A + E G IT VA+K L A+ +E+ EF ++
Sbjct: 1804 REQITLAKFLGSGAFGEVFQGNAKDL-ERPG-ITP----VAIKTLRKGASAQEKTEFLQE 1857
Query: 743 VRILAALSSPHLARVLGAC--RSPPLAVVLEYLELGDLCAFLRAA--IPPTAA------T 792
R+++ H+ R+LG C PPL +VLE +E GDL ++LRA+ + P+ +
Sbjct: 1858 ARLMSHFRHKHVLRLLGVCLDTDPPL-LVLELMEAGDLLSYLRASRSLQPSDSHALRLQD 1916
Query: 793 LLHIATQIAAGMQYLESLNFVHRDLAARNCLIG----KGYQIKISDFGTDNEAYTCDYYK 848
LL + +A G +YLE L+FVHRDLA RNCL+ + +KI DFG + Y DYY+
Sbjct: 1917 LLAMCEDVARGCRYLEELHFVHRDLACRNCLVSAKDRENRVVKIGDFGLARDIYKNDYYR 1976
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
+G LP+RW A ES++ G +T++SDVWAF V + EI SL ++PY T+ EV L
Sbjct: 1977 KEGEGLLPVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSL-GQQPYPARTNIEV---LH 2032
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
H++A + + CP L++LML CW D RP+F
Sbjct: 2033 HVRAGGRL----SKPLNCPLALHQLMLRCW-SDVDTRPSF 2067
>UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte
receptor tyrosine protein kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to leukocyte receptor
tyrosine protein kinase - Nasonia vitripennis
Length = 1472
Score = 162 bits (394), Expect = 4e-38
Identities = 104/283 (36%), Positives = 148/283 (52%), Gaps = 26/283 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
+ PR + ++ L +GAFG V+ GV +Y+ SE+ VAVK L +T + +F
Sbjct: 914 QIPRDSVTLVKPLGQGAFGEVF----QGVYKYS---RSEEHPVAVKTLPSVSTSQAEADF 966
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT-- 792
+ I++ P++ + +G + P +VLE L GDL FLR P PT T
Sbjct: 967 MMEALIMSKFEHPNIVQFIGISFDKHPRYIVLELLAGGDLKNFLREERPRPDRPTTLTMQ 1026
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
L+ A +A G +Y+E F+HRD+AARNCL+ G G +KI+DFG + Y DYY+
Sbjct: 1027 SLIMCAYDVAKGCKYMEEARFIHRDIAARNCLLSCKGPGRVVKIADFGMARDIYRSDYYR 1086
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP++W ES L G +TTK+DVWAF V L EI S PY + EV+
Sbjct: 1087 KGGKAMLPIKWMPPESFLDGIFTTKTDVWAFGVLLWEIMSF-GYMPYTGCANREVMS--- 1142
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G E R GCP +Y +M CW +RP+F I
Sbjct: 1143 -MVTSGGRLE---RPAGCPDPIYGIMTRCWHPHPEERPSFSSI 1181
>UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin
receptor; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to insulin receptor - Nasonia vitripennis
Length = 1714
Score = 162 bits (394), Expect = 4e-38
Identities = 102/283 (36%), Positives = 152/283 (53%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ ++ +L G+FG VY A V + E R AVK + +AT +ER EF
Sbjct: 1123 EVPRKKVHLLKELGNGSFGMVYEGIAKDVVKGK----PEMRC-AVKTVNENATDRERVEF 1177
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA----------AIPP 788
+ ++ ++ H+ R+LG + P VV+E + GDL +LR+ PP
Sbjct: 1178 LNEASVMKGFNTHHVVRLLGVVSQGQPTLVVMELMVNGDLKTYLRSHRPDVCENFSRQPP 1237
Query: 789 TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK 848
T ++ +A +IA GM YL + FVHRDLAARNC++ +KI DFG + Y DYY+
Sbjct: 1238 TLNRIMRMALEIADGMAYLAAKKFVHRDLAARNCMVSDDLTVKIGDFGMTRDVYETDYYR 1297
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
+ LP+RW A ES+ G +T+ SDVW++ V L E+ +L +PY+ L++ +VL
Sbjct: 1298 KGTKGLLPVRWMAPESLKDGVFTSFSDVWSYGVVLWEMVTLA-SQPYQGLSNDQVL---- 1352
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G+ E R CP LY +M + W RPTF +I
Sbjct: 1353 RYVIDGGVME---RPENCPDILYGMMRQTWCHKATRRPTFIDI 1392
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 162 bits (394), Expect = 4e-38
Identities = 102/272 (37%), Positives = 148/272 (54%), Gaps = 17/272 (6%)
Query: 684 HRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDV 743
H L + ++L +G FG+V G+ Y GA +K VAVK L D+ +EF R+
Sbjct: 463 HDLHLGAELGQGEFGSVL----KGL--YKGA-DGKKIEVAVKTLRLDSQGHGEKEFAREA 515
Query: 744 RILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFL--RAAIPPTAATLLHIATQIA 801
I+ L+ P + +++G P+ +V E + +G L +L R P TL A +IA
Sbjct: 516 GIMVTLNHPCIVKLIGITNGKPMMMVQELISMGALVDYLYERKQPIPDVLTLKLWAAEIA 575
Query: 802 AGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWA 860
+GM YLE+ FVHRDLAARN L+ Q+KISDFG DYYK P++W
Sbjct: 576 SGMMYLETKRFVHRDLAARNILVQSMKQVKISDFGLSRAVGANSDYYKASQGGRWPVKWY 635
Query: 861 AWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECV 920
A ES+ G ++ SDVW++ +TL E++S PY +T EVLD + +L + EC
Sbjct: 636 APESINFGTFSHASDVWSYGITLWEMFSF-GDAPYGDMTGAEVLDRVENL---NYRLEC- 690
Query: 921 DRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
CP +YELML CW + +RPTF +++
Sbjct: 691 --PRDCPSSIYELMLRCWSLEPNERPTFAQLY 720
>UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor;
n=1; Bombyx mori|Rep: Insulin receptor-like protein
precursor - Bombyx mori (Silk moth)
Length = 1472
Score = 162 bits (394), Expect = 4e-38
Identities = 100/283 (35%), Positives = 150/283 (53%), Gaps = 27/283 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + I +L +G+FG VY +G+ + E R A+K + AT +ER EF
Sbjct: 1076 EVTRDSIHFIRELGQGSFGMVY----EGIAKEIVKGKPETRC-AIKTVNEHATDRERIEF 1130
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA------------- 785
+ ++ A + H+ R+LG R P VV+E +E GDL +LR+
Sbjct: 1131 LNEASVMKAFDTFHVVRLLGVVSRGQPTLVVMELMERGDLKTYLRSMRPDAEGSLPSSPP 1190
Query: 786 IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD 845
+PPT +L +A +IA GM YL + FVHRDLAARNC++ +K+ DFG + Y D
Sbjct: 1191 VPPTLQNILQMAIEIADGMAYLSAKKFVHRDLAARNCMVAGDLTVKVGDFGMTRDIYETD 1250
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
YY+ + +P+RW + ES+ G +++ SD W++ V L E+ +L +PY+ L++ +VL
Sbjct: 1251 YYRKGTKGLMPVRWMSPESLKDGVFSSSSDAWSYGVVLWEMATLA-MQPYQGLSNEQVL- 1308
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ G+ E R CP LYELM CW RPTF
Sbjct: 1309 ---RYVVEGGVME---RPEQCPDRLYELMRACWTHRPSARPTF 1345
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 162 bits (394), Expect = 4e-38
Identities = 94/233 (40%), Positives = 129/233 (55%), Gaps = 10/233 (4%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
VA+K L D ++ +EF R+ +++ L+ P + +LG C PP+ +V E +E+G L +
Sbjct: 513 VAMKTLHKDKMVQGEKEFLREALVMSQLNHPCIVSLLGVCLGPPMILVQELVEMGALLDY 572
Query: 782 LRAAIPPTAATLLHI-ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
L P L + A+QIA GM YLE FVHRDLAARN L+ Q+KISDFG
Sbjct: 573 LMDYQPEIQEVDLKLWASQIAFGMMYLELKRFVHRDLAARNILLANKKQVKISDFGLSRA 632
Query: 841 AYT-CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
T DYY+ P+RW A ES+ G ++TKSDVW++ +TL E+++ PY +T
Sbjct: 633 VGTGSDYYQAKQGGRWPVRWYAPESINYGTFSTKSDVWSYGITLWEMFTF-GDLPYGEMT 691
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
EV+ L H G E D CP Y +ML CW D RPTF E+H
Sbjct: 692 GNEVVSFLEHC----GRLEKPDE---CPIHTYSIMLSCWHIDPNKRPTFNELH 737
>UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG8250-PA
- Tribolium castaneum
Length = 1284
Score = 161 bits (392), Expect = 6e-38
Identities = 103/283 (36%), Positives = 145/283 (51%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
+ PR +LR++ L +GAFG VY G T E VAVK L +T + +F
Sbjct: 814 DIPREQLRLVKALGQGAFGEVY----QGFYRQRPCDTVEMP-VAVKTLPEMSTSQAEMDF 868
Query: 740 ERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPP-------TAA 791
+ I++ + P++ +G C P +VLE L GDL FLR + P T
Sbjct: 869 LMEALIMSKFNHPNIVHFIGVCFDKHPRFIVLELLAGGDLKNFLRESRPKPERGSPLTMK 928
Query: 792 TLLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
L+ IA +A G +YLE F+HRD+AARNCL+ G G +KI+DFG + Y DYY+
Sbjct: 929 DLVLIAVDVAKGCKYLEDNRFIHRDIAARNCLLTTKGPGRVVKIADFGMSRDVYRSDYYR 988
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G+ LP++W E+ L G +T+K+DVW+F V L EI S+ PY + EV+
Sbjct: 989 KGGKAMLPIKWMPPEAFLDGIFTSKTDVWSFGVLLWEIMSM-GYMPYTGCANREVM---- 1043
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
L G +D CP +Y +M +CW RPTF I
Sbjct: 1044 QLVTSGGR---LDPPANCPGPIYGIMTQCWHPTPEQRPTFATI 1083
>UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; Homo
sapiens|Rep: Tyrosine-protein kinase receptor - Homo
sapiens (Human)
Length = 1310
Score = 161 bits (391), Expect = 8e-38
Identities = 100/283 (35%), Positives = 150/283 (53%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR + +I L GAFG VY + G+P + VAVK L + ++ +F
Sbjct: 800 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQ-----VAVKTLPEVCSEQDELDF 854
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT-- 792
+ I++ + ++ R +G + +S P ++LE + GDL +FLR P P++
Sbjct: 855 LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAML 914
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
LLH+A IA G QYLE +F+HRD+AARNCL+ G G KI DFG + Y YY+
Sbjct: 915 DLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYR 974
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G LP++W E+ + G +T+K+D W+F V L EI+SL PY ++ EVL+ ++
Sbjct: 975 KGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSL-GYMPYPSKSNQEVLEFVT 1033
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G +D CP +Y +M +CW+ DRP F I
Sbjct: 1034 ----SGGR---MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAII 1069
>UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;
n=37; Euteleostomi|Rep: ALK tyrosine kinase receptor
precursor - Homo sapiens (Human)
Length = 1620
Score = 161 bits (391), Expect = 8e-38
Identities = 100/283 (35%), Positives = 150/283 (53%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR + +I L GAFG VY + G+P + VAVK L + ++ +F
Sbjct: 1110 EVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQ-----VAVKTLPEVCSEQDELDF 1164
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT-- 792
+ I++ + ++ R +G + +S P ++LE + GDL +FLR P P++
Sbjct: 1165 LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAML 1224
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
LLH+A IA G QYLE +F+HRD+AARNCL+ G G KI DFG + Y YY+
Sbjct: 1225 DLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYR 1284
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
G LP++W E+ + G +T+K+D W+F V L EI+SL PY ++ EVL+ ++
Sbjct: 1285 KGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSL-GYMPYPSKSNQEVLEFVT 1343
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G +D CP +Y +M +CW+ DRP F I
Sbjct: 1344 ----SGGR---MDPPKNCPGPVYRIMTQCWQHQPEDRPNFAII 1379
>UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine
protein kinase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to tyrosine protein kinase -
Strongylocentrotus purpuratus
Length = 1566
Score = 161 bits (390), Expect = 1e-37
Identities = 109/326 (33%), Positives = 164/326 (50%), Gaps = 33/326 (10%)
Query: 652 RSKQSTRSPSQQEILLDL-KRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPE 710
R + T +Q L+ L + L T + E PR + + KL EGAFGTVY EA
Sbjct: 985 RKVKRTEQHIKQLTLMGLGEGALITLDEWEMPRENVVLNRKLGEGAFGTVYGGEA----- 1039
Query: 711 YNGAITSEK-RLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAV 768
+ K VAVK L A+++E+ +F + ++ + ++ +LG C R P+
Sbjct: 1040 ---LLDDNKWAAVAVKTLKLGASVEEKLDFLSEAEVMKRFNHKNIVNLLGVCTRGEPMYA 1096
Query: 769 VLEYLELGDLCAFL-------------RAAIPPTAATLLHIATQIAAGMQYLESLNFVHR 815
V+E++ GDL FL R L + + IA+G+ YL S+N+VHR
Sbjct: 1097 VMEFMLYGDLKTFLLGRRHLVGEGVYERNQHVMCPDQLTSMVSDIASGLSYLASINYVHR 1156
Query: 816 DLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSD 875
DLA RNCL+ Y +KI DFG Y DYY++ R LP+RW A ES+ G +TT SD
Sbjct: 1157 DLACRNCLVDASYTVKIGDFGMTRALYDSDYYRLGKRSKLPVRWMAPESLTEGIFTTMSD 1216
Query: 876 VWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELML 935
VW+ V ++E+ + PY+ L++ EVLD + + + + GC L LM+
Sbjct: 1217 VWSLGVVIYEVVTF-GSFPYQELSNAEVLDYIRNRNS-------LRPPEGCSPALGALMM 1268
Query: 936 ECWRRDELDRPTFGEIH-LFLQRKSL 960
+CW RPT +++ + QR L
Sbjct: 1269 QCWAIQPQHRPTAKDVNDILCQRPHL 1294
>UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor
precursor; n=8; Eumetazoa|Rep: Putative insulin-like
peptide receptor precursor - Hydra attenuata (Hydra)
(Hydra vulgaris)
Length = 1477
Score = 161 bits (390), Expect = 1e-37
Identities = 98/279 (35%), Positives = 154/279 (55%), Gaps = 21/279 (7%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++ +I +L +G+FG V+ A G+ ++ +E R VAVK +A++ +R +
Sbjct: 1038 ELNREKIELIRELGQGSFGMVFEGIAHGIGDH-----AELR-VAVKTTNENASIHDRIQI 1091
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR------AAIPPTAAT 792
++ I+ A + H+ +++G + P VV+E + GDL ++L+ IP
Sbjct: 1092 LQEASIMKAFNCNHVVKLIGVVSQGQPTFVVMELMGRGDLKSYLKERRPDDGGIPLMRQE 1151
Query: 793 LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 852
+ + +IA GM YL + FVH DLAARNC++ + +KI DFG + Y +YY+ DG+
Sbjct: 1152 IYQMVAEIADGMAYLAARKFVHCDLAARNCMVASDFTVKIGDFGMARDIYERNYYRKDGK 1211
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
LP+RW A ES+ G ++T SDVW+F V L EI +L +PY+ T+ +VL +
Sbjct: 1212 SLLPIRWMAPESLKDGIFSTASDVWSFGVVLWEICTLA-SQPYQGKTNEQVL----NFVL 1266
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+G +D GC L E M CW RD RP+F EI
Sbjct: 1267 SNGH---LDYPEGCDYQLREFMSLCWHRDPKMRPSFLEI 1302
>UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular
organisms|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 159 bits (386), Expect = 3e-37
Identities = 95/268 (35%), Positives = 145/268 (54%), Gaps = 22/268 (8%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
++M KL +GAFG V+ A G + VAVK C + +RE+F ++ I
Sbjct: 634 IKMGRKLGKGAFGDVWEAALKGQGK-----------VAVK-TCRSTDVPDREKFLQEAEI 681
Query: 746 LAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA-AIPPTAATLLHIATQIAAG 803
L P++ +++G + P+ +V+E + G L +LR A T LLH++ G
Sbjct: 682 LKQYDHPNIVKLIGVSWDTEPVLIVMELMPGGSLLDYLRKKAAQMTKGKLLHMSIDACGG 741
Query: 804 MQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWE 863
M+YLES N +HRDLAARNCL+G+ +KISDFG E Y G +P++W A E
Sbjct: 742 MEYLESKNCIHRDLAARNCLVGENDIVKISDFGMSREEEGGMYTVQSGTRQIPIKWTAPE 801
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
++ G+YT+ SDVW+F V L+E++S PY +++ E + Q D G +
Sbjct: 802 ALNYGRYTSASDVWSFGVLLYEVFS-GGSTPYPGMSNAE-----TRTQVDSGY--RMPPP 853
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
GCP +++++M CW D DRP FG +
Sbjct: 854 QGCPAEIHQIMQLCWAYDAEDRPKFGAV 881
>UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra
vulgaris|Rep: Receptor tyrosine kinase 90 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 848
Score = 159 bits (386), Expect = 3e-37
Identities = 95/271 (35%), Positives = 144/271 (53%), Gaps = 14/271 (5%)
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
F L+ I L G FG V+ A A G+ E G T LVAVK F
Sbjct: 583 FNYENLQEIIVLGYGKFGKVFKAYAKGICE-EGTDT----LVAVKVFEETPVNNVLSAFN 637
Query: 741 RDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQI 800
++ L + ++ R+LG R P ++ EY ELGDL +L+ +++ LH+ T I
Sbjct: 638 KETEDLMQFQNSYVVRLLGLVRESPFCIITEYSELGDLKEYLQTNKNTSSSARLHMCTCI 697
Query: 801 AAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWA 860
A GM YL +L++VHRDLAARNC++ ++K+S N Y DYY ++ + P+RW
Sbjct: 698 AKGMSYLATLHYVHRDLAARNCILFSQNEVKVSFLSLCNTTYKDDYYLLNNLL-APVRWL 756
Query: 861 AWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECV 920
A ES+ Y K+DVW+F+VT+ EI+S +P+ +++ EV++ + G +
Sbjct: 757 APESIRENIYNEKTDVWSFSVTMWEIFS-SEVQPFYGVSNEEVVNRI-------GKDLQL 808
Query: 921 DRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
CP+ LY++M CW + DRPTF E+
Sbjct: 809 TIPSNCPKTLYKIMTRCWLVNAFDRPTFDEL 839
>UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 1084
Score = 157 bits (381), Expect = 1e-36
Identities = 100/283 (35%), Positives = 149/283 (52%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + + L GAFG VY A G+P + VAVK L + ++ +F
Sbjct: 493 EVSRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSPLQ-----VAVKTLPEVCSEQDELDF 547
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT-- 792
+ I++ S ++ R +G + ++ P ++LE + GDL F+R P P++ T
Sbjct: 548 LMEALIISKFSHQNIVRCVGVSLQAMPRFILLELMTGGDLKTFMRETRPRPEHPSSLTMV 607
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
LL+IA IA G QYLE F+HRD+AARNCL+ G G KI DFG + Y YY+
Sbjct: 608 DLLNIARDIAKGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYR 667
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
GR LP++W E+ + G +T+K+D W+F V L EI+SL PY ++ EVL+ ++
Sbjct: 668 KGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSL-GYMPYPSRSNQEVLEFVT 726
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G +D CP +Y +M +CW+ DRP F I
Sbjct: 727 ----NGGR---MDPPKNCPGPVYRIMTQCWQHQPEDRPNFSTI 762
>UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic
lymphoma kinase (Ki-1),; n=1; Danio rerio|Rep: PREDICTED:
similar to anaplastic lymphoma kinase (Ki-1), - Danio
rerio
Length = 1387
Score = 157 bits (380), Expect = 2e-36
Identities = 101/283 (35%), Positives = 150/283 (53%), Gaps = 24/283 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR + + L GAFG VY A G+P + VAVK L + ++ +F
Sbjct: 789 EVPRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSPMQ-----VAVKTLPEVCSEQDELDF 843
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT-- 792
+ I++ S ++ R +G + ++ P ++LE + GDL +FLR P P++ T
Sbjct: 844 LMEALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSLTMV 903
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
LL+IA IA G QYLE F+HRD+AARNCL+ G G KI DFG + Y YY+
Sbjct: 904 DLLNIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRASYYR 963
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
GR LP++W E+ + G +T+K+D W+F V L EI+SL PY ++ EVL+ ++
Sbjct: 964 KGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSL-GYMPYPSRSNQEVLEFVT 1022
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G +D CP +Y +M + W+ DRP F I
Sbjct: 1023 ----NGGR---MDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTI 1058
>UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019144 - Anopheles gambiae
str. PEST
Length = 687
Score = 157 bits (380), Expect = 2e-36
Identities = 101/294 (34%), Positives = 151/294 (51%), Gaps = 30/294 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPRHRL++ + L EGAFG V+ EA + + G + AVK L +A+ ER +
Sbjct: 378 EFPRHRLKVFNILGEGAFGQVWRCEATDIDGHEGV-----SVTAVKTLKENASEAERNDL 432
Query: 740 ERDVRILAALSSPHL--ARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP-------- 788
++++L +L PH+ R+LG C P+ V+LEY+ +G L FLR +
Sbjct: 433 LSELQVLKSLE-PHINVVRLLGCCTEKDPIFVILEYVNMGKLQTFLRNSRVEKHYGNTHG 491
Query: 789 -----TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
T+ L Q+A GM +L S +HRDLAARN LI + K++DFG + T
Sbjct: 492 KSKILTSGDLTSFMYQVARGMDFLTSRGIIHRDLAARNILITDDHTCKVADFGFARDIVT 551
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
Y+ LP+RW A ES+ +T KSD+W+F + + EI +L PY + +V
Sbjct: 552 SKVYERKSEGRLPIRWMATESLYDNIFTVKSDIWSFGILMWEIVTL-GSTPYPGIAAADV 610
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ + DG +++ C R+LY +M CW D +RP F E+ L R
Sbjct: 611 MRKVR-----DGY--RLEKPEHCRRELYNIMFYCWAADPNERPGFPEVVEMLDR 657
>UniRef50_Q9Y1X7 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 385
Score = 156 bits (379), Expect = 2e-36
Identities = 105/328 (32%), Positives = 165/328 (50%), Gaps = 29/328 (8%)
Query: 641 LGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTV 700
+ SL +V + + P+ E + +RR + PR L + KL +G +G V
Sbjct: 60 IAVEESLVFNVTEQLTQVKPTYTETEIATQRRETMLGSRQHPRGDLVLEEKLGDGEYGPV 119
Query: 701 YVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGA 760
Y A++ +P G+ R+V VK L DA+ R FE+D+ +L + + ++ VL
Sbjct: 120 YRAQSYNLPGKKGS-----RVVTVKMLLEDASEAHRIAFEKDIALLNSFNHVNVMGVLAV 174
Query: 761 CRSP-PLAVVLEYLELGDLCAFLRAA-------IPP--------TAATLLHIATQIAAGM 804
C P ++L+ G L LR A IP + A+LLH+A + GM
Sbjct: 175 CTGESPQCILLDAGLPGSLLTHLREAKRLARQKIPAKQLLVDMTSPASLLHMADDVCLGM 234
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWES 864
YL S FV +DLAARNC++G ++K++DFG + Y + GR P PLRW A ES
Sbjct: 235 AYLSSQAFVVKDLAARNCIVGADGRVKVADFGVGPSVFPEAYCTLHGR-PSPLRWMAAES 293
Query: 865 VLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAP 924
+ G+Y+T SD+WAF V + E+++ PY ++D EV + ++ + G + +
Sbjct: 294 IESGQYSTASDIWAFGVFIWELFT-GGDLPYTEMSDDEV---VRYVTKECGKLQMPE--- 346
Query: 925 GCPRDLYELMLECWRRDELDRPTFGEIH 952
CP D+Y +ML CW + R F +H
Sbjct: 347 NCPSDVYTIMLSCWENEAKSRQLFLTLH 374
>UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to
ENSANGP00000013218; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000013218 - Nasonia
vitripennis
Length = 972
Score = 155 bits (375), Expect = 7e-36
Identities = 108/296 (36%), Positives = 152/296 (51%), Gaps = 31/296 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR RL + L EG FG V A+A + + G T VAVK L DA+ E +
Sbjct: 495 EFPRSRLSIEQVLGEGEFGRVLRAKAQDIAGWQGQTT-----VAVKTLKEDASASELADL 549
Query: 740 ERDVRILAALSSPHLARVLGACRSP--PLAVVLEYLELGDLCAFLRAA----------IP 787
+ ++L P++ R+LGAC + P+ +++E+ E G L +LR + I
Sbjct: 550 LSEYQLLKEAQHPNVIRLLGACTTAGGPIYLIIEFAEFGSLRNYLRRSRHLESEGRPSID 609
Query: 788 P------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
P T +L A QI+ GM YL + VHRDLAARN L+G G KISDFG +
Sbjct: 610 PVVNYTITPRDILSFAWQISKGMAYLADIKLVHRDLAARNVLLGAGKVCKISDFGLTRDV 669
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
Y D Y + +P++W A ES+ YT+KSDVW+F V L E+ +L PY + D
Sbjct: 670 YEDDAYLKRSKGRVPVKWMAPESLADHVYTSKSDVWSFGVLLWELVTL-GASPYPGV-DV 727
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
L NL L+A M ++ C LY+LM+ CW + RP+F E+ +R
Sbjct: 728 HNLYNL--LKAGYRM----EKPANCSHQLYKLMVSCWHDEPGMRPSFKELTCHWER 777
>UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2;
Cellia|Rep: Tyrosine-protein kinase receptor - Anopheles
gambiae str. PEST
Length = 1318
Score = 154 bits (374), Expect = 1e-35
Identities = 98/285 (34%), Positives = 150/285 (52%), Gaps = 27/285 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR + + +L +G+FG VY G+ G + A+K + +AT +ER+ F
Sbjct: 987 EVPREHIIQLEELGQGSFGMVY----KGIMTKLGNDVNVP--CAIKTVTENATERERDSF 1040
Query: 740 ERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLR------------AAI 786
+ I+ + H+ R+ G P V++E + GDL ++LR +
Sbjct: 1041 LIEATIMKEFHTHHVVRLYGVVSVGQPTLVIMELMANGDLKSYLRRHRPDYENGEESSPQ 1100
Query: 787 PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
PPT + +A +IA GM YL + FVHRDLAARNC++ + +KI DFG + Y DY
Sbjct: 1101 PPTLKQIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDY 1160
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
Y+ + LP+RW A ES+ G +++ SDV+++ V L E+ +L +PY+ LT+ +VL
Sbjct: 1161 YRKGTKGFLPVRWMAPESLKDGMFSSSSDVFSYGVVLWEMATLA-SQPYQGLTNDQVL-- 1217
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G+ E R CP LYELM CW+ RP+F +I
Sbjct: 1218 --RYVIDGGVME---RPENCPDKLYELMRICWQHRASARPSFIDI 1257
>UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 277
Score = 154 bits (373), Expect = 1e-35
Identities = 95/279 (34%), Positives = 145/279 (51%), Gaps = 21/279 (7%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+EFPRH L + L G++G ++A A G+ + + +V VK L + RE+
Sbjct: 1 MEFPRHDLEALRTLGNGSYGRAFLARASGIKD-----GERETMVVVKSLIAKDDIV-RED 54
Query: 739 FERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATL---- 793
F R++ L + ++ +LG CR S P ++ E E GDL FL + +TL
Sbjct: 55 FTRELESLVNMEHSNVVSLLGVCRDSEPFYMIFECFEKGDLKQFLLSCNDNGRSTLTSSH 114
Query: 794 -LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 852
L + + I +GM YL + FVH+DLAARNC++ K Q+KI + Y +YY+ +
Sbjct: 115 KLTMCSNIVSGMSYLAANKFVHKDLAARNCMVTKDLQVKIGFLNLSYDLYNAEYYRFN-N 173
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
+ +PLRW E++ +T KSDVW+F V EIYSL + PY +D EVL +
Sbjct: 174 ILIPLRWMPSEAIFHDDFTEKSDVWSFGVLAWEIYSL-GQIPYTDRSDEEVLKCVK---- 228
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
DD + + CP ++ +M +CW + DRP F I
Sbjct: 229 DDLR---LPKPDNCPDNMANVMKKCWEPNPNDRPNFDMI 264
>UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3
precursor; n=30; Tetrapoda|Rep: Tyrosine-protein kinase
receptor TYRO3 precursor - Homo sapiens (Human)
Length = 890
Score = 154 bits (373), Expect = 1e-35
Identities = 114/357 (31%), Positives = 175/357 (49%), Gaps = 33/357 (9%)
Query: 614 LLTKRMGETLSQQATELVGEPMDTLPDLGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRL 673
LL KR ET QA + V + RS N R ++ + I +LK +L
Sbjct: 450 LLRKRRKETRFGQAFDSVMARGEPAVHFRAARSFNRE-RPERIEATLDSLGISDELKEKL 508
Query: 674 ETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATL 733
E + P + + L +G FG+V A+ + + +G+ VAVK L D
Sbjct: 509 EDVLI---PEQQFTLGRMLGKGEFGSVREAQ---LKQEDGSFVK----VAVKMLKADIIA 558
Query: 734 K-EREEFERDVRILAALSSPHLARVLGAC-------RSPPLAVVLEYLELGDLCAFLRAA 785
+ EEF R+ + PH+A+++G R P V+L +++ GDL AFL A+
Sbjct: 559 SSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLAS 618
Query: 786 ------IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
TL+ IA GM+YL S NF+HRDLAARNC++ + + ++DFG
Sbjct: 619 RIGENPFNLPLQTLIRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSR 678
Query: 840 EAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
+ Y+ DYY+ LP++W A ES+ YT +SDVWAF VT+ EI + + PY +
Sbjct: 679 KIYSGDYYRQGCASKLPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTR-GQTPYAGIE 737
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ E+ + L G + + P C D+Y+LM +CW D RP+F + + L+
Sbjct: 738 NAEIYNYLI-----GG--NRLKQPPECMEDVYDLMYQCWSADPKQRPSFTCLRMELE 787
>UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase MER
precursor; n=30; root|Rep: Proto-oncogene
tyrosine-protein kinase MER precursor - Homo sapiens
(Human)
Length = 999
Score = 154 bits (373), Expect = 1e-35
Identities = 110/303 (36%), Positives = 162/303 (53%), Gaps = 31/303 (10%)
Query: 668 DLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFL 727
+L+ +LE VI+ R+ L + L EG FG+V + + +G TS K VAVK +
Sbjct: 572 ELQNKLEDV-VID--RNLLILGKILGEGEFGSVMEGN---LKQEDG--TSLK--VAVKTM 621
Query: 728 CHD-ATLKEREEFERDVRILAALSSPHLARVLGACRS------PPLAVVLEYLELGDLCA 780
D ++ +E EEF + + S P++ R+LG C P V+L +++ GDL
Sbjct: 622 KLDNSSHREIEEFLSEAACMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHT 681
Query: 781 FL---RAAIPPT---AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISD 834
+L R P TLL IA GM+YL + NF+HRDLAARNC++ + ++D
Sbjct: 682 YLLYSRLETGPKHIPLQTLLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVAD 741
Query: 835 FGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRP 894
FG + Y+ DYY+ +P++W A ES+ YT+KSDVWAF VT+ EI + P
Sbjct: 742 FGLSKKIYSGDYYRQGRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTR-GMTP 800
Query: 895 YEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLF 954
Y + + E+ D L H +C+D +LYE+M CWR D LDRPTF + L
Sbjct: 801 YPGVQNHEMYDYLLHGHRLKQPEDCLD-------ELYEIMYSCWRTDPLDRPTFSVLRLQ 853
Query: 955 LQR 957
L++
Sbjct: 854 LEK 856
>UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2]; n=15;
Eumetazoa|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (DIR) (DInr) (dIRH) [Contains: Insulin-like
receptor subunit alpha; Insulin-like receptor subunit
beta 1; Insulin-like receptor subunit beta 2] -
Drosophila melanogaster (Fruit fly)
Length = 2144
Score = 154 bits (373), Expect = 1e-35
Identities = 103/305 (33%), Positives = 154/305 (50%), Gaps = 36/305 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + ++ L +G+FG VY P NG R A+K + +AT +ER F
Sbjct: 1365 EVLRENIIQLAPLGQGSFGMVYEGILKSFPP-NGV----DRECAIKTVNENATDRERTNF 1419
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA-------------- 784
+ ++ + H+ R+LG C R P VV+E ++ GDL ++LRA
Sbjct: 1420 LSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYL 1479
Query: 785 --------AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG 836
PPT + +A +IA GM YL + FVHRDLAARNC++ +KI DFG
Sbjct: 1480 NRIGVTGNVQPPTYGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFG 1539
Query: 837 TDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ Y DYY+ + LP+RW ES+ G Y++ SDV++F V L E+ +L +PY+
Sbjct: 1540 MTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLA-AQPYQ 1598
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
L++ +VL D G+ E R CP L++LM CW RP+F +I +L+
Sbjct: 1599 GLSNEQVL----RYVIDGGVME---RPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLE 1651
Query: 957 RKSLN 961
+ N
Sbjct: 1652 PQCPN 1656
>UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR2 precursor; n=36; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR2
precursor - Homo sapiens (Human)
Length = 943
Score = 153 bits (372), Expect = 2e-35
Identities = 104/316 (32%), Positives = 159/316 (50%), Gaps = 31/316 (9%)
Query: 654 KQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNG 713
+Q SPSQ ++ + L + + + E +R + +L E FG VY G
Sbjct: 442 RQLMASPSQ-DMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGP----- 495
Query: 714 AITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEY 772
A + + VA+K L A REEF + + A L P++ +LG + PL+++ Y
Sbjct: 496 APGEQTQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSY 555
Query: 773 LELGDLCAFL--RAAIPPTAAT--------------LLHIATQIAAGMQYLESLNFVHRD 816
GDL FL R+ +T +H+ QIAAGM+YL S + VH+D
Sbjct: 556 CSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKD 615
Query: 817 LAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDV 876
LA RN L+ +KISD G E Y DYYK+ G LP+RW A E+++ GK++ SD+
Sbjct: 616 LATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDI 675
Query: 877 WAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLE 936
W++ V L E++S +PY ++ +V++ + + Q + C D CP +Y LM+E
Sbjct: 676 WSYGVVLWEVFSY-GLQPYCGYSNQDVVEMIRNRQ----VLPCPD---DCPAWVYALMIE 727
Query: 937 CWRRDELDRPTFGEIH 952
CW RP F +IH
Sbjct: 728 CWNEFPSRRPRFKDIH 743
>UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase receptor -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1161
Score = 153 bits (370), Expect = 3e-35
Identities = 104/296 (35%), Positives = 156/296 (52%), Gaps = 29/296 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR + ++ L GAFG VY + G+ NG T+ + VA+K L + ++ +F
Sbjct: 560 EVPRKNITLLRALGHGAFGEVYEGQVLGM---NGENTAMQ--VAIKTLPEICSEQDEMDF 614
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT------ 792
+ I++ S ++ R +G + + P ++LE + GD+ +FLR P T +
Sbjct: 615 LMEALIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSML 674
Query: 793 -LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYK 848
LLH+A IA G +YLE +F+HRD+AARNCL+ G KI DFG + Y YY+
Sbjct: 675 ELLHMARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRASYYR 734
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
GR LP++W E+ L G +T K+D W+F V L EI+SL PY T+ EVL+ ++
Sbjct: 735 KGGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFSL-GYMPYPCKTNQEVLEFVT 793
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNYAT 964
G +D CP +Y +M +CW+ RP F I L+R +NY T
Sbjct: 794 ----GGGR---MDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTI---LER--INYCT 837
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 153 bits (370), Expect = 3e-35
Identities = 95/281 (33%), Positives = 150/281 (53%), Gaps = 25/281 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E P+ + + K+ +G FG V+ A + ++ +VAVK L + + +F
Sbjct: 340 EIPKSSIILKEKIGQGQFGEVFKA-----------VWNKTTIVAVKTLKPSSC--DAADF 386
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA--AIPPTAATLLHI 796
R+ + + L P+L ++ C ++ P +V EY+ G L +L++ L+ +
Sbjct: 387 LREAQTMKRLHHPNLIQLYAVCTQTEPFYIVTEYMSKGSLLNYLQSPEGNALNMQCLIMM 446
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
A +IA GM YLES +HRDLAARN L+G+ + +KI+DFG + +Y G P
Sbjct: 447 AAKIAPGMAYLESRRHIHRDLAARNVLVGEQHAVKIADFGLARMIHNREYVAHAG-ARFP 505
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W + E+ ++T KSDVW+F + L EI + R PY + + EVL Q D G
Sbjct: 506 IKWTSPEAANYSRFTIKSDVWSFGILLTEIVTY-GRSPYPGMHNAEVL-----RQVDAGY 559
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ + PGCP +LY+LMLECW DE RP+F IH L++
Sbjct: 560 --RMSKPPGCPPELYDLMLECWAADENKRPSFATIHFRLEQ 598
>UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4
variant; n=28; Eumetazoa|Rep: Fibroblast growth factor
receptor 4 variant - Homo sapiens (Human)
Length = 1034
Score = 153 bits (370), Expect = 3e-35
Identities = 106/290 (36%), Positives = 150/290 (51%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR RL + L EG FG V AEA G+ + A + VAVK L +A+ K+ +
Sbjct: 693 EFPRDRLVLGKPLGEGCFGQVVRAEAFGM---DPARPDQASTVAVKMLKDNASDKDLADL 749
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LG C + PL V++E G+L FLRA PP
Sbjct: 750 VSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 809
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
+ L+ A Q+A GMQYLES +HRDLAARN L+ + +KI+DFG
Sbjct: 810 RSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGV 869
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F + L EI++L PY +
Sbjct: 870 HHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTL-GGSPYPGI--- 925
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
V + S L+ M DR P CP +LY LM ECW RPTF ++
Sbjct: 926 PVEELFSLLREGHRM----DRPPHCPPELYGLMRECWHAAPSQRPTFKQL 971
>UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase
receptor ret precursor; n=59; Eumetazoa|Rep:
Proto-oncogene tyrosine-protein kinase receptor ret
precursor - Homo sapiens (Human)
Length = 1114
Score = 153 bits (370), Expect = 3e-35
Identities = 115/338 (34%), Positives = 167/338 (49%), Gaps = 43/338 (12%)
Query: 649 PSVRSKQSTRSPS----QQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAE 704
P S R PS + ++ +D + LE EFPR L + L EG FG V A
Sbjct: 684 PVSYSSSGARRPSLDSMENQVSVDAFKILEDPKW-EFPRKNLVLGKTLGEGEFGKVVKAT 742
Query: 705 ADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RS 763
A + G T VAVK L +A+ E + + +L ++ PH+ ++ GAC +
Sbjct: 743 AFHLKGRAGYTT-----VAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQD 797
Query: 764 PPLAVVLEYLELGDLCAFLRAA--IPP----------------------TAATLLHIATQ 799
PL +++EY + G L FLR + + P T L+ A Q
Sbjct: 798 GPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQ 857
Query: 800 IAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRW 859
I+ GMQYL + VHRDLAARN L+ +G ++KISDFG + Y D Y + +P++W
Sbjct: 858 ISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKW 917
Query: 860 AAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFEC 919
A ES+ YTT+SDVW+F V L EI +L PY + E L NL L+ M
Sbjct: 918 MAIESLFDHIYTTQSDVWSFGVLLWEIVTL-GGNPYPGIPP-ERLFNL--LKTGHRM--- 970
Query: 920 VDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+R C ++Y LML+CW+++ RP F +I L++
Sbjct: 971 -ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1007
>UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain]; n=2; Aedes
aegypti|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain] - Aedes aegypti
(Yellowfever mosquito)
Length = 1390
Score = 153 bits (370), Expect = 3e-35
Identities = 94/284 (33%), Positives = 151/284 (53%), Gaps = 25/284 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R+ + + +L +G+FG VY + + G ++ A+K + AT +E++ F
Sbjct: 1019 EVERNHIIQLEELGQGSFGMVYKGI---LTQLRGEKCNQP--CAIKTVNESATAREKDSF 1073
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA-----------AIP 787
+ ++ ++ H+ R+LG + P V++E + GDL ++LR P
Sbjct: 1074 LLEASVMKQFNTHHVVRLLGVVSQGDPTLVIMELMANGDLKSYLRRHRPDYEMRRSIRQP 1133
Query: 788 PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
PT ++ +A +IA G+ L + FVHRDLAARNC++ +KI DFG + Y DYY
Sbjct: 1134 PTLRQIIQMAIEIADGIGVLSAKKFVHRDLAARNCMVADDMTVKIGDFGMTRDIYETDYY 1193
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
+ + LP+RW A ES+ G +++ SDV+++ V L E+ +L +PY+ LT+ +VL
Sbjct: 1194 RKGTKGFLPVRWMAPESLKDGIFSSSSDVFSYGVVLWEMATLA-SQPYQGLTNDQVL--- 1249
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D G+ E R CP +LY LM CW+ RPTF EI
Sbjct: 1250 -RYVIDGGVME---RPENCPDNLYNLMRRCWQHRPTARPTFMEI 1289
>UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1
precursor; n=2; Lymnaea stagnalis|Rep: Putative
neurotrophin receptor LTRK 1 precursor - Lymnaea
stagnalis (Great pond snail)
Length = 794
Score = 152 bits (369), Expect = 4e-35
Identities = 97/311 (31%), Positives = 159/311 (51%), Gaps = 32/311 (10%)
Query: 667 LDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKF 726
L K+ + TT + ++ + EGAFG V++ + + N E +VAVK
Sbjct: 485 LTKKKHVATTCPKTVRLQTILLMRVIGEGAFGRVFLGTCAHLIQKN-----EFAIVAVKT 539
Query: 727 LCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA 785
L + + +FER+ +LA + ++ G C S ++ E++E GDL +LR
Sbjct: 540 LKGSCSDSLKRDFEREAEMLATIEHANIVTFYGVCTESDQWMMIFEFMENGDLNKYLRMH 599
Query: 786 IPPTA-----------------ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGY 828
P A L+ I QIA+ M+YL +FVHRDLA RNCL+G
Sbjct: 600 GPDAAFLKDRDSMDSDEGQLTREQLMKIVLQIASAMEYLALQHFVHRDLATRNCLVGCDL 659
Query: 829 QIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
+K+ DFG + YT DYY+V+G LP+RW ES++ +TT+SDVW+F VTL E+++
Sbjct: 660 VVKLGDFGMSRDVYTTDYYRVEGTAMLPVRWMPPESIIYRTFTTESDVWSFGVTLWEVFT 719
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAP-GCPRDLYELMLECWRRDELDRPT 947
++P+ ++ EV++++ + + + R P C +Y +M CW+ + DR T
Sbjct: 720 Y-GKQPWFEYSNSEVIEHIKNSRT-------LKRPPRTCTDGVYRVMQGCWKPNPQDRLT 771
Query: 948 FGEIHLFLQRK 958
+I L+ +
Sbjct: 772 MKDIAELLREE 782
>UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3;
Eutheria|Rep: HOOK3-RET fusion protein - Homo sapiens
(Human)
Length = 776
Score = 151 bits (367), Expect = 7e-35
Identities = 107/303 (35%), Positives = 154/303 (50%), Gaps = 38/303 (12%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR L + L EG FG V A A + G T VAVK L +A+ E +
Sbjct: 380 EFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTT-----VAVKMLKENASPSELRDL 434
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA--IPP-------- 788
+ +L ++ PH+ ++ GAC + PL +++EY + G L FLR + + P
Sbjct: 435 LSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGS 494
Query: 789 --------------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISD 834
T L+ A QI+ GMQYL + VHRDLAARN L+ +G ++KISD
Sbjct: 495 RNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISD 554
Query: 835 FGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRP 894
FG + Y D Y + +P++W A ES+ YTT+SDVW+F V L EI +L P
Sbjct: 555 FGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTL-GGNP 613
Query: 895 YEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLF 954
Y + E L NL L+ M +R C ++Y LML+CW+++ RP F +I
Sbjct: 614 YPGIPP-ERLFNL--LKTGHRM----ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKD 666
Query: 955 LQR 957
L++
Sbjct: 667 LEK 669
>UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor
precursor; n=8; Amniota|Rep: Leukocyte tyrosine kinase
receptor precursor - Mus musculus (Mouse)
Length = 888
Score = 151 bits (367), Expect = 7e-35
Identities = 96/275 (34%), Positives = 143/275 (52%), Gaps = 24/275 (8%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILA 747
++ L GAFG VY G+P + + VA+K L + ++ +F + I++
Sbjct: 508 LLRALGHGAFGEVYEGLVTGLPGDSSPLP-----VAIKTLPELCSHQDELDFLMEALIIS 562
Query: 748 ALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAA-------IPPTAATLLHIATQ 799
S ++ R +G + RS P ++LE + GD+ +FLR + P T LL +A
Sbjct: 563 KFSHQNIVRCVGLSFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQLAQD 622
Query: 800 IAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
IA G YLE +F+HRD+AARNCL+ G KI DFG + Y YY+ GR LP
Sbjct: 623 IAQGCHYLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQASYYRKGGRTLLP 682
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W E++L G +T+K+D W+F V L EI+SL PY T+ EVLD ++
Sbjct: 683 VKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSL-GYMPYPGHTNQEVLDFIA-------T 734
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+D CP +Y +M +CW+ RP FG I
Sbjct: 735 GNRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSI 769
>UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca
precursor; n=2; Diptera|Rep: Tyrosine kinase receptor
Cad96Ca precursor - Drosophila melanogaster (Fruit fly)
Length = 773
Score = 151 bits (367), Expect = 7e-35
Identities = 99/294 (33%), Positives = 148/294 (50%), Gaps = 30/294 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR+RL+ + L EGAFG V+ EA + G T VAVK L AT +R++
Sbjct: 464 EFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITT-----VAVKTLKESATEVDRKDL 518
Query: 740 ERDVRILAALSSPHL--ARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPP-------- 788
++ ++ +L PH+ +LG C P V+LEY+ G L +LR++
Sbjct: 519 LSELEVMKSLE-PHINVVHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHG 577
Query: 789 -----TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
T+ L Q+A GM YL S +HRDLAARN LI + K++DFG + T
Sbjct: 578 KSNVLTSCDLTSFMYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVIT 637
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
Y+ LP+RW A ES+ ++ KSD+W+F + + EI +L PY ++ +V
Sbjct: 638 SKIYERKSEGKLPIRWMATESLYDNIFSVKSDIWSFGILMWEIVTL-GSTPYPGISAADV 696
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ + DG +++ C R+LY +M CW D +RP F EI L +
Sbjct: 697 MRKVR-----DGY--RLEKPEHCRRELYNIMYYCWSHDPQERPLFAEIIQMLDK 743
>UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan
receptor; n=2; Nematostella vectensis|Rep: Receptor
tyrosine kinase-like orphan receptor - Nematostella
vectensis
Length = 715
Score = 151 bits (366), Expect = 9e-35
Identities = 102/298 (34%), Positives = 151/298 (50%), Gaps = 28/298 (9%)
Query: 673 LETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDAT 732
++TT+ + + LR++ +L EG +G VY E E G + + LV H+
Sbjct: 426 VKTTSKVREIKESLRLLKELGEGDYGKVYFGEITTKSE--GRLMATSVLVVSLRESHEVD 483
Query: 733 LKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP---P 788
+ R+EF + L P++ ++G C +S P V+ EYLE G L +L P P
Sbjct: 484 V--RDEFFEKAEAWSKLQHPNIITIVGMCNKSVPTCVLYEYLEYGTLHEYLVRNAPIDDP 541
Query: 789 TAAT----------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
A L+ IA Q+AAGM YL S N VH DLA RNC++G G +KI+D
Sbjct: 542 EAEEEIADPLWCDGLISIAYQVAAGMNYLSSNNIVHGDLATRNCMVGPGRTVKITDVALT 601
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
Y+ DYY+ R PLP+RW A E++L ++T ++D+W+F V L E++S +P+
Sbjct: 602 RLGYSHDYYRQLHRRPLPVRWMAPEAILSYRFTPETDIWSFGVLLWELFSY-GAQPHFGF 660
Query: 899 TDCEVLDNLSHLQADDGMFEC-VDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
++ +V+ L + C VD CP +Y LM ECW RP F IH L
Sbjct: 661 SNEDVMFRLRECI----LLPCPVD----CPASVYRLMKECWDILPPSRPRFSTIHTHL 710
>UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4
precursor; n=9; Eutheria|Rep: Fibroblast growth factor
receptor 4 precursor - Mus musculus (Mouse)
Length = 799
Score = 151 bits (366), Expect = 9e-35
Identities = 106/290 (36%), Positives = 149/290 (51%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR RL + L EG FG V AEA G+ TS VAVK L +A+ K+ +
Sbjct: 458 EFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPSRPDQTST---VAVKMLKDNASDKDLADL 514
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LG C + PL V++E G+L FLRA PP
Sbjct: 515 VSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGP 574
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
+ L+ A Q+A GMQYLES +HRDLAARN L+ + +KI+DFG
Sbjct: 575 RSSEGPLSFPALVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDDVMKIADFGLARGV 634
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F + L EI++L PY +
Sbjct: 635 HHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFEILLWEIFTL-GGSPYPGI--- 690
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
V + S L+ M +R P CP +LY LM ECW RPTF ++
Sbjct: 691 PVEELFSLLREGHRM----ERPPNCPSELYGLMRECWHAAPSQRPTFKQL 736
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 151 bits (365), Expect = 1e-34
Identities = 89/232 (38%), Positives = 130/232 (56%), Gaps = 10/232 (4%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
VA+K L D ++EF R+ +++ L P + +++G C PP+ +V E + G L F
Sbjct: 591 VALKTLHADHLQTGQKEFLREAKVMCGLDHPCIVKLMGVCLGPPMMLVQELVSQGALLDF 650
Query: 782 LRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN-E 840
L+ TA+ L ATQIA+GM YLE FVHRDLAARN L+ Q KISDFG
Sbjct: 651 LQND-SITASDLKLWATQIASGMMYLEGKKFVHRDLAARNILLENKGQAKISDFGLSRAT 709
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
DYY+ P++W A ES+ G ++ SDVW F VTL E+ S +PY T
Sbjct: 710 GANNDYYRSTTGGRWPVKWYAPESIYYGTFSHSSDVWGFGVTLWEMNSR-GAQPYGEKTG 768
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIH 952
EV+ Q ++G ++R GCP+++Y++M +CW +RPTF +++
Sbjct: 769 AEVIK-----QIENG--HRLNRPEGCPQNVYQIMNKCWSYKPCNRPTFSQLN 813
>UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-like
growth factor 1 receptor precursor (Insulin-like growth
factor I receptor) (IGF-I receptor) (CD221 antigen); n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Insulin-like growth factor 1 receptor precursor
(Insulin-like growth factor I receptor) (IGF-I receptor)
(CD221 antigen) - Tribolium castaneum
Length = 1277
Score = 151 bits (365), Expect = 1e-34
Identities = 97/278 (34%), Positives = 146/278 (52%), Gaps = 24/278 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R+ + +I +L +G+FGTVY G I S + A+K + +++ + EF
Sbjct: 914 EIDRNDIEIIRELGKGSFGTVY----------EGLIKSRQYPCAIKTISEKSSISSKMEF 963
Query: 740 ERDVRILAALSSPH-LARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIPP----TAATL 793
+ ++ + S H + ++LG R V++E +E GDL ++LR P T +
Sbjct: 964 LNEGSVMKSFSETHHVIKLLGIVSRGDRPFVIMELMERGDLKSYLRRCRGPSQNLTTNEI 1023
Query: 794 LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRV 853
+A++IA GM YL FVHRDLAARNC++ +KI DFG + Y DYY+
Sbjct: 1024 YRMASEIADGMAYLSVKKFVHRDLAARNCMVAADRTVKIGDFGMARDIYETDYYRKGTAG 1083
Query: 854 PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQAD 913
LP+RW A ES+ G +TT SDVW++ V L E+ +L PY+ L EVL ++
Sbjct: 1084 LLPIRWMAPESLADGVFTTDSDVWSYGVVLWEMATLA-ELPYQGLGAEEVLQFVT----- 1137
Query: 914 DGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G +D P C L+++M CW+ DRPTF I
Sbjct: 1138 SG--RTLDMPPQCSDLLHKIMSACWKWRPNDRPTFFSI 1173
>UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:
Protein sevenless - Drosophila melanogaster (Fruit fly)
Length = 2554
Score = 151 bits (365), Expect = 1e-34
Identities = 109/326 (33%), Positives = 177/326 (54%), Gaps = 43/326 (13%)
Query: 649 PSVRSKQSTRSPSQQEILLDLKRRLETT----NVIEFPR---HRLRMISKLAEGAFGTVY 701
PS+ S ST +QQ+++ R TT ++ P+ +L+++ L GAFG VY
Sbjct: 2166 PSIWSNLSTLQ-TQQQLMAVRNRAFSTTLSDADIALLPQINWSQLKLLRFLGSGAFGEVY 2224
Query: 702 VAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC 761
+G + + E + VA+K L A+ E E ++ ++++ ++ ++G C
Sbjct: 2225 ----EG--QLKTEDSEEPQRVAIKSLRKGAS--EFAELLQEAQLMSNFKHENIVCLVGIC 2276
Query: 762 -RSPPLAVVLEYLELGDLCAFLRAAIP-------PTA----ATLLHIATQIAAGMQYLES 809
+ +++++E++E GDL ++LRAA PTA + LL + +A G YLE
Sbjct: 2277 FDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSELLAMCIDVANGCSYLED 2336
Query: 810 LNFVHRDLAARNCLIGKGY-------QIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAW 862
++FVHRDLA RNCL+ + +KI DFG + Y DYY+ +G LP+RW +
Sbjct: 2337 MHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKSDYYRKEGEGLLPVRWMSP 2396
Query: 863 ESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDR 922
ES++ G +TT+SDVWAF V EI +L ++PY + EV L+H++ + G + +
Sbjct: 2397 ESLVDGLFTTQSDVWAFGVLCWEILTL-GQQPYAARNNFEV---LAHVK-EGGRLQ---Q 2448
Query: 923 APGCPRDLYELMLECWRRDELDRPTF 948
P C LY L+L CWR D +RP+F
Sbjct: 2449 PPMCTEKLYSLLLLCWRTDPWERPSF 2474
>UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 4 SCAF14752, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 810
Score = 150 bits (364), Expect = 2e-34
Identities = 113/363 (31%), Positives = 175/363 (48%), Gaps = 35/363 (9%)
Query: 592 SNTALSDSSNYDYAVPELSSAPLLTKRMGETLSQQATELVGEPMDTLPDLGTRRSLNPSV 651
S L++ Y A+P + LL ++ GE L Q E G T+P L + V
Sbjct: 470 SERPLAEQEWYHGAIPRTEAQELL-RQQGEFLGQYRFE--GTGFTTIPQLIEHHFSSKQV 526
Query: 652 RSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEY 711
+K+S ++ D K L +V+ + L +G FG V+
Sbjct: 527 ITKKSG-VVLLNPVVKDKKWILNHEDVV--------LGELLGKGNFGEVF---------- 567
Query: 712 NGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVL 770
G + +K VAVK D + + F + RIL P++ +++G C + P+ +V+
Sbjct: 568 KGTLQRDKTPVAVKTCKEDLPSELKIRFLSEARILKQYDHPNIVKLIGVCTQRQPIYIVM 627
Query: 771 EYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQ 829
E + GD ++LR LL A AAGM YLES N +HRDLAARNCL+G
Sbjct: 628 ELVPGGDFLSYLRKKKDELKTKQLLRFAVDAAAGMAYLESKNCIHRDLAARNCLVGDNNA 687
Query: 830 IKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSL 889
+KISDFG + Y G +P++W A E++ G+Y+++SDVW++ + L E +SL
Sbjct: 688 LKISDFGMSRQE-DDGIYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSYGILLWETFSL 746
Query: 890 CRRRPYEHLTDCEVLDNLSHLQADDG-MFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
PY +T+ + + Q + G C R CP D+Y++M CW+ + DRP F
Sbjct: 747 -GMCPYPGMTNQQARE-----QVEKGYRMACPQR---CPDDVYKVMQRCWQYNPEDRPKF 797
Query: 949 GEI 951
E+
Sbjct: 798 SEL 800
>UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to Alk
CG8250-PA - Apis mellifera
Length = 1436
Score = 150 bits (363), Expect = 2e-34
Identities = 97/286 (33%), Positives = 148/286 (51%), Gaps = 26/286 (9%)
Query: 677 NVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER 736
++ + PR + +I L +GAFG V+ GV Y ++++ VAVK + + +
Sbjct: 879 DLTQIPRECITLIRPLGQGAFGEVF----QGVYRYR---RNQEQPVAVKAIPSSSRPQTE 931
Query: 737 EEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP----PTAA 791
+F + I++ + P++ +G P +VLE L G+L FLR P PT+
Sbjct: 932 ADFMMEALIMSKFNHPNIVHFIGVSFERNPKYIVLELLAGGNLKNFLREERPRADRPTSL 991
Query: 792 T---LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCD 845
L+ +A G +Y+E F+HRD+AARNCL+ G G +KI+DFG + Y D
Sbjct: 992 RMQDLIMCGFDVANGCKYMEEARFIHRDIAARNCLLTSKGPGRIVKIADFGMAKDIYRSD 1051
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
YY+ G+ LP++W ES L G +TTK+DVWAF V L EI S PY T+ E +
Sbjct: 1052 YYRKGGKAMLPIKWMPPESFLDGIFTTKTDVWAFGVLLWEIMSF-GYIPYTGCTNREAMT 1110
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ + +++ GCP +Y LM CW DRP+F I
Sbjct: 1111 MVT-------LGGRLEKPAGCPDPIYGLMTRCWHPRPEDRPSFATI 1149
>UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Danio
rerio|Rep: Spleen protein tyrosine kinase - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 586
Score = 149 bits (362), Expect = 3e-34
Identities = 94/264 (35%), Positives = 145/264 (54%), Gaps = 20/264 (7%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDA-TLKEREEFERDVRILAAL 749
+L G FGTV GV + + +++VAVK L +D ++E R+ ++ L
Sbjct: 327 ELGSGNFGTVL----RGVYQ----MKKTQKVVAVKILKNDDDNAAVKDEMLREANVMQQL 378
Query: 750 SSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQIAAGMQYLES 809
+P++ R++G C + L +V+E ELG L FL+ T L + Q++ GM+YLE
Sbjct: 379 DNPYIVRMIGICEAENLMLVMELAELGPLHKFLQKNKHITVKNLTELVHQVSMGMKYLEE 438
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD--YYKVDGRVPLPLRWAAWESVLR 867
NFVHRDLAARN L+ + KISDFG ++A T D YYK G PL+W A E +
Sbjct: 439 HNFVHRDLAARNVLLVTQHYAKISDFGL-SKALTEDENYYKAKGHGKWPLKWYAPECMNY 497
Query: 868 GKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCP 927
K+++KSDVW+F V + E +S ++PY+ + EV+ + + Q + P CP
Sbjct: 498 LKFSSKSDVWSFGVLMWEAFSY-GQKPYKGMKGNEVIQMIENGQR-------MSAPPDCP 549
Query: 928 RDLYELMLECWRRDELDRPTFGEI 951
++Y+LM +CW +RP F +
Sbjct: 550 PEMYDLMKKCWTYKPDERPGFSVV 573
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 149 bits (361), Expect = 4e-34
Identities = 86/238 (36%), Positives = 125/238 (52%), Gaps = 10/238 (4%)
Query: 722 VAVKFLCHDATLKERE-EFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCA 780
VAVK L + E E + R +A L H+ R++G C+ +VLE LG +
Sbjct: 917 VAVKTLKPNQIANSGEREILAEARTMAQLKHRHIVRLIGVCKEEQFMLVLELAPLGPINK 976
Query: 781 FLRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
+L+ + TL + Q+A GM YLES FVHRDLAARN L+ + KISDFG
Sbjct: 977 YLKKRPDVSVHTLTELMHQVALGMAYLESCKFVHRDLAARNVLLVTRHFAKISDFGMSKA 1036
Query: 841 A-YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
+ DYY+ PL+W A E + ++ +KSDVW++ +TL E+YS RPY +
Sbjct: 1037 LNFGSDYYRAATAGKWPLKWYAPECIYYFRFDSKSDVWSYGITLWEVYSY-GERPYRDMK 1095
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
++L L D G+ + R CP +Y +M +CW + + RPTF E+ L + R
Sbjct: 1096 GAQILAML-----DQGL--RLSRPSRCPESIYSIMQQCWNFEGVHRPTFAELVLTISR 1146
>UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 295
Score = 149 bits (361), Expect = 4e-34
Identities = 108/298 (36%), Positives = 154/298 (51%), Gaps = 34/298 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR R++ L GAFG V A+A G+ G++ VAVK + + + R +
Sbjct: 3 EFPRDRVKTSVVLGSGAFGVVMKADAQGIKGCVGSLP-----VAVKIVKENDSDTARRDL 57
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA------------ 785
++ +L + P++ +LG C R PL V++E+ + GDL ++LR
Sbjct: 58 MAELDLLKLIDPHPNVIGLLGCCTRGDPLMVIVEFCQYGDLQSYLRHCRGIEDKYYEQIY 117
Query: 786 -IPP---TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
+P TA LL Q A GM +L S+ VHRDLAARN LI + K+SDFG +
Sbjct: 118 MVPEKKLTAKDLLSFGIQAARGMAHLASMKVVHRDLAARNILIDEKSVCKVSDFGFARDI 177
Query: 842 YTCDYY--KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
Y D+Y K G P++W A ES+L G TTKSDVW++ V L EI +L PY +
Sbjct: 178 YVEDHYTRKTQGG-RFPIKWMAIESLLDGVSTTKSDVWSYGVLLWEIVTL-GASPYPGMN 235
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
EV++ L DG +D+ C +LY +ML+CW+ RPTF EI L +
Sbjct: 236 SQEVINFL-----QDGY--RMDKPKHCLDELYAVMLDCWQLSAQRRPTFVEISRLLNK 286
>UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Apis mellifera|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Apis mellifera
Length = 1374
Score = 149 bits (360), Expect = 5e-34
Identities = 100/289 (34%), Positives = 153/289 (52%), Gaps = 28/289 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PRHR+ + KL EGAFGTVY EA PE G + VAVK L ++ +E+ +F
Sbjct: 936 EIPRHRVVINRKLGEGAFGTVYGGEAF-FPE-KGWLA-----VAVKTLKIGSSTEEKLDF 988
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA------------AI 786
+V ++ ++ ++LG C +S P+ V+E++ GDL +L A +
Sbjct: 989 LSEVEVMKQFEHKNIIKLLGVCIKSEPVLTVMEFMLYGDLKTYLLARRHLVNDNSYEDSD 1048
Query: 787 PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
+ L +A +A + YL +VHRD+A+RNCL+ +K+ DFG Y DY
Sbjct: 1049 EISNKKLTAMALDVARALSYLAQSKYVHRDIASRNCLVNAQRVVKLGDFGMTRLMYENDY 1108
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
YK + R LP+RW A ES+ G ++ SDVW++ V L+EI + P++ +++ EV
Sbjct: 1109 YKFNRRGMLPVRWMAPESLGLGIFSPASDVWSYGVLLYEIITF-GSFPFQGMSNIEV--- 1164
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
L+H+++ + + G L LM CWR D + RPT EI FL
Sbjct: 1165 LNHVKSGNSLMV----PKGVKIQLENLMYSCWRLDHIKRPTAPEIVEFL 1209
>UniRef50_Q29JN3 Cluster: GA21826-PA; n=2; Endopterygota|Rep:
GA21826-PA - Drosophila pseudoobscura (Fruit fly)
Length = 117
Score = 149 bits (360), Expect = 5e-34
Identities = 61/108 (56%), Positives = 81/108 (75%)
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
+P+RW +WESVL GK+TTKSDVW+FAV L EI + R +PYEH+TD V++N+ H+ DD
Sbjct: 1 MPIRWMSWESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHMTDENVIENIGHIYQDD 60
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNY 962
M E + CPR++Y+LM ECW+R+E RP F EIHLFLQRK+L +
Sbjct: 61 KMHELLPMPVNCPREIYDLMCECWQRNESSRPNFREIHLFLQRKNLGF 108
>UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Rep:
Isoform of FGFR2 - Homo sapiens (Human)
Length = 709
Score = 149 bits (360), Expect = 5e-34
Identities = 100/290 (34%), Positives = 148/290 (51%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR +L + L EG FG V +AEA G+ + E VAVK L DAT K+ +
Sbjct: 363 EFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDK---PKEAVTVAVKMLKDDATEKDLSDL 419
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LGAC + PL V++EY G+L +LRA PP
Sbjct: 420 VSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIN 479
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
T L+ Q+A GM+YL S +HRDLAARN L+ + +KI+DFG +
Sbjct: 480 RVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDI 539
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
DYYK LP++W A E++ YT +SDVW+F V + EI++L PY +
Sbjct: 540 NNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL-GGSPYPGIPVE 598
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E+ L +G +D+ C +LY +M +CW RPTF ++
Sbjct: 599 ELFKLLK-----EG--HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQL 641
>UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein
kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor
tyrosine kinase MerTK).; n=1; Xenopus tropicalis|Rep:
Proto-oncogene tyrosine-protein kinase MER precursor (EC
2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). -
Xenopus tropicalis
Length = 763
Score = 148 bits (359), Expect = 6e-34
Identities = 106/303 (34%), Positives = 158/303 (52%), Gaps = 31/303 (10%)
Query: 668 DLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFL 727
DL+++LE V R+ L + L EG FG+V +G +Y+ T+ K VAVK +
Sbjct: 456 DLQQKLEDVMV---ERNLLNLGKVLGEGEFGSVM----EGELQYSDG-TNHK--VAVKTM 505
Query: 728 CHDA-TLKEREEFERDVRILAALSSPHLARVLGAC------RSPPLAVVLEYLELGDLCA 780
D + +E EEF + + + P++ R+LG C R P V+L +++ GDL +
Sbjct: 506 KMDNFSQREIEEFLSEAACMKDFNHPNVIRLLGVCLEVGPRRIPKPMVILPFMKYGDLHS 565
Query: 781 FL---RAAIPPTAA---TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISD 834
FL R P TL+ IA GM+YL S NF+HRDLAARNC++ + ++D
Sbjct: 566 FLLSSRIGSGPQHVPLRTLVKFMIDIATGMEYLSSRNFLHRDLAARNCMLRDDMTVCVAD 625
Query: 835 FGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRP 894
FG + Y+ DYY+ +P++W A ES+ YT KSDVWAF VT+ EI S P
Sbjct: 626 FGLSKKIYSGDYYRQGRIAKMPVKWIAVESLADRIYTVKSDVWAFGVTMWEI-STRGMTP 684
Query: 895 YEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLF 954
Y + + E+ D L + + + P C DLY +M +CW D RP+F +
Sbjct: 685 YPGVQNHEIYDYLL-------VGHRLKQPPECLDDLYTVMYQCWLSDPTCRPSFTALREN 737
Query: 955 LQR 957
L++
Sbjct: 738 LEK 740
>UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 148 bits (359), Expect = 6e-34
Identities = 94/279 (33%), Positives = 147/279 (52%), Gaps = 19/279 (6%)
Query: 675 TTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK 734
+T E P ++++ ++ G FGTVY + E + +AVK L ++ K
Sbjct: 524 STVATEIPPKYIKLVEEIGGGEFGTVYKGMWN---ERKPPVP-----IAVKTLKPGSSDK 575
Query: 735 EREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAAT- 792
R++F + I+ P++ ++ G + P +++E+++ G L +LR +
Sbjct: 576 MRDDFLTEASIMGQFHHPNVIKLYGVITKVEPAMIIMEFMDNGSLYYYLRHNDEKLSLQQ 635
Query: 793 LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGR 852
LL +A +AAGMQYL + +VHRDLAARN L+ K K++DFG E T D Y V
Sbjct: 636 LLKMACGVAAGMQYLSEVGYVHRDLAARNILVSKDEVCKVADFGLSRET-TNDEYDVKKG 694
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
+P+RW A E++ K+TT SDVW++ V L E+ S ++PYE + VLD L
Sbjct: 695 GKIPVRWTAPEAISYRKFTTASDVWSYGVLLWEVMSY-GQQPYEDWDNQMVLDKL----- 748
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ G + + CP +YELM CW + DRPTF E+
Sbjct: 749 ESGY--RLQKPKDCPSTVYELMQSCWSAEHTDRPTFKEL 785
>UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor b - Nematostella vectensis
Length = 591
Score = 148 bits (359), Expect = 6e-34
Identities = 102/291 (35%), Positives = 151/291 (51%), Gaps = 34/291 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R ++ ++ L EGAFG V A+A G+P VAVK L DAT E +
Sbjct: 268 ELDRSQISLLGILGEGAFGRVVKADAIGLPNMPYRCN-----VAVKMLXEDATEHELADL 322
Query: 740 ERDVRILAALSSP-HLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP-PTAAT---- 792
++ ++ + ++ ++GAC + PL VV+EY G+L FLRA P P A
Sbjct: 323 VSEMEVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTE 382
Query: 793 ----------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAY 842
L+ + Q+A GM+YLES +HRDLAARN L+ + IKI+DFG + +
Sbjct: 383 PPREKLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIH 442
Query: 843 TCDYYK--VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
DYY+ DGR LP++W A E++ YT +SDVWA+ + + EI + PY +
Sbjct: 443 DIDYYRKTTDGR--LPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTF-GGSPYPGIPL 499
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ + L +G +++ C D+Y LML CW + RPTF EI
Sbjct: 500 WKLFELLK-----EGY--RMEQPVNCQDDVYALMLRCWHENPNQRPTFAEI 543
>UniRef50_Q179Z3 Cluster: Tyrosine-protein kinase; n=1; Aedes
aegypti|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 343
Score = 148 bits (358), Expect = 8e-34
Identities = 104/297 (35%), Positives = 155/297 (52%), Gaps = 34/297 (11%)
Query: 677 NVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK-E 735
+++E P LR+ ++ +GAFG V++A A +P NG +LVAVK L K E
Sbjct: 31 DLLEVPHSCLRIGREIGKGAFGHVFIANASKLPHCNGP-----KLVAVKQLKKCPKRKPE 85
Query: 736 REEFERDVRILAALSS-PHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATL 793
EEF ++ ++ + P++ +LG C PL +++EY+ GDL P ++
Sbjct: 86 FEEFLDEIAMMKQVGKHPNIVALLGCCTLKEPLTMIMEYIGCGDLVTMYTTLSGPNDSSR 145
Query: 794 LH--------------IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
H A QIA GM++LE N HRDLAARN LI + +KISDFG
Sbjct: 146 EHSALEYLLDHKELHDFARQIACGMKHLEEKNITHRDLAARNILIDEKKTLKISDFGLSR 205
Query: 840 EAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
T Y + +PLRW + E++ Y++KSDVWAF + L EI +L PY ++
Sbjct: 206 ---TGIYVNTRNK-KVPLRWLSIEAMRDHLYSSKSDVWAFGIVLWEIGTL-GGYPYPTVS 260
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ E+L L + +DR C +LYELML CW+ + DRP+F +I+ L+
Sbjct: 261 NHELLSFLHNGNR-------LDRPENCSAELYELMLHCWKAEPDDRPSFADIYKSLE 310
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 147 bits (356), Expect = 1e-33
Identities = 93/272 (34%), Positives = 145/272 (53%), Gaps = 25/272 (9%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE--REEFERDVRI 745
++ K+ G FG VY A+ + + +VAVK C TL E +++F ++ RI
Sbjct: 541 LLDKIGRGNFGDVYRAQ----------LKNSNDVVAVK-TCR-VTLPEDHKKKFLQEGRI 588
Query: 746 LAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQIAAGM 804
L P++ +++G C + P+ +V+E + G L FLR T A L+ + AAGM
Sbjct: 589 LKQYDHPNIVKLIGICVQKQPIMIVMELVPGGSLLTFLRKKTALTDAQLMKMCLDAAAGM 648
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWES 864
+YLES N +HRDLAARNCL+G +KISDFG E +Y DG +P++W A E+
Sbjct: 649 RYLESKNCIHRDLAARNCLVGYNNVVKISDFGMSREEE--EYIVSDGMKQIPIKWTAPEA 706
Query: 865 VLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAP 924
+ GKYT+ DVW++ + EI+S PY L++ + + + D G +
Sbjct: 707 LNFGKYTSLCDVWSYGILCWEIFSR-GGTPYSGLSNSKAREKI-----DAGY--RMPAPD 758
Query: 925 GCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
P ++Y LML CW +RP F +I+ ++
Sbjct: 759 NTPDEMYRLMLRCWEYKPENRPNFEQIYTVVE 790
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 147 bits (356), Expect = 1e-33
Identities = 83/235 (35%), Positives = 128/235 (54%), Gaps = 10/235 (4%)
Query: 719 KRLVAVKFLCHDA-TLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGD 777
++ VAVK L +D L REE R+ ++ L +P++ R++G C + L +V+E ELG
Sbjct: 382 EKTVAVKILKNDEDNLSVREEMLREANVMQQLDNPYIVRMIGICEAENLMLVMELAELGP 441
Query: 778 LCAFLRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
L FL+ + + + Q++ GM+YLE NFVHRDLAARN L+ + KISDFG
Sbjct: 442 LHKFLQKHKQISMKNITELVHQVSVGMKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGL 501
Query: 838 DNE-AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
A YYK G P++W A E + K+++KSDVW+F V + E +S ++PY+
Sbjct: 502 SKAVAEDKSYYKAKGHGKWPVKWYAPECINYFKFSSKSDVWSFGVLMWEAFSF-GQKPYK 560
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ EV+ + Q ++ CP ++ +LM CW DRP+F +
Sbjct: 561 GMKGNEVMQMIESGQR-------MEAPANCPSEMSDLMQACWTYKVEDRPSFSVV 608
>UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4;
Endopterygota|Rep: Tyrosine-protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 959
Score = 147 bits (356), Expect = 1e-33
Identities = 104/297 (35%), Positives = 155/297 (52%), Gaps = 31/297 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR +L + L EGAFG V +AEA+G+ + + +VAVK L T + ++
Sbjct: 620 EFPRSKLVLGKSLGEGAFGKVVMAEANGLVKGQAST-----VVAVKMLKEGHTDADVKDL 674
Query: 740 ERDVRILAALSSP-HLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTA------- 790
++ ++ + ++ +LG C + PL V++EY G+L FLR+ TA
Sbjct: 675 VCEMEVMKMIGKHVNIINLLGCCCKDGPLYVIVEYAPHGNLKDFLRSHRFGTANYEDMIS 734
Query: 791 ----------ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
L+ A QIA GM++L S +HRDLAARN L+ GY +KI+DFG +
Sbjct: 735 GEKEKKILTQKELISFAYQIARGMEHLASRRCIHRDLAARNVLVSDGYVMKIADFGLARD 794
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
++ +YY+ LP+RW A ES+ Y ++SDVW+F V L EI +L PY +
Sbjct: 795 IHSQEYYRKTTTGKLPIRWMAPESLEEKFYDSQSDVWSFGVLLWEIMTL-GGNPYSSIPT 853
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ L L HL+ + +++ P C D+Y M ECW +RPTF EI L R
Sbjct: 854 WDNL--LEHLKKG----KRLEQPPLCSIDIYLFMRECWHYRPEERPTFSEIVQHLDR 904
>UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2
precursor; n=11; Eumetazoa|Rep: Fibroblast growth factor
receptor 2 precursor - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 817
Score = 147 bits (356), Expect = 1e-33
Identities = 99/290 (34%), Positives = 148/290 (51%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EF R +L + L EG FG V +AEA G+ + E VAVK L DAT K+ +
Sbjct: 471 EFSRDKLTLGKPLGEGCFGQVVMAEALGIDKDK---PKEAVTVAVKMLKDDATEKDLSDL 527
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LGAC + PL V++EY G+L +LRA PP
Sbjct: 528 VSEMEMMKMIGRHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIA 587
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
T L+ Q+A GM+YL S +HRDLAARN L+ + +KI+DFG +
Sbjct: 588 RVSDEPLTFKDLVSCTYQVARGMEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDV 647
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F V + EI++L PY +
Sbjct: 648 HNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL-GGSPYPGIPVE 706
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E+ L +G +D+ C +LY +M +CW RPTF ++
Sbjct: 707 ELFKLLK-----EG--HRMDKPANCTNELYMMMKDCWHAISSHRPTFKQL 749
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 147 bits (355), Expect = 2e-33
Identities = 92/263 (34%), Positives = 135/263 (51%), Gaps = 19/263 (7%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EG FG VY D + + VA+K L + REEF R+ R++ +
Sbjct: 470 LGEGEFGAVYEGLFDSP-------SGTQEPVAIKMLRDTHNIATREEFLREARLMMTFNH 522
Query: 752 PHLARVLGACRSPPLAVVLEYLELGDLCAFLRA---AIPPTAATLLHIATQIAAGMQYLE 808
+ +++G PPL +V E + LG + A+L I P + A+QIA GM+YLE
Sbjct: 523 HCIVKLIGFSEGPPLLMVQELVSLGSMLAYLLEFPDRINPNYELKVW-ASQIACGMKYLE 581
Query: 809 SLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRG 868
+ VHRDLAARN L+ +Q KISDFG + DYYK P++W A ES G
Sbjct: 582 EIRLVHRDLAARNILLASKHQAKISDFGLSRTFGSNDYYKATAGGKWPIKWYAPESYNYG 641
Query: 869 KYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPR 928
++ SDVW++ +TL E++S +PY EV+D + G + + + CP
Sbjct: 642 TFSHASDVWSYGITLWEMFSY-GEQPYGDRRGTEVID-----LVEKG--DRLAQPEQCPD 693
Query: 929 DLYELMLECWRRDELDRPTFGEI 951
+Y++M +CW DRPTF E+
Sbjct: 694 HVYKVMQKCWSYSPADRPTFQEL 716
>UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homolog
2 precursor; n=4; Coelomata|Rep: Fibroblast growth
factor receptor homolog 2 precursor - Drosophila
melanogaster (Fruit fly)
Length = 1052
Score = 147 bits (355), Expect = 2e-33
Identities = 100/297 (33%), Positives = 153/297 (51%), Gaps = 35/297 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR +L + S L EGAFG V +AEA+G+P + + +VAVK + + T +
Sbjct: 706 EIPRQQLSLGSILGEGAFGRVVMAEAEGLPR---SPQLAETIVAVKMVKEEHTDTDMASL 762
Query: 740 ERDVRILAALSSP-HLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP---------- 787
R++ ++ + ++ +LG C + PL V++EY G+L FL+ P
Sbjct: 763 VREMEVMKMIGKHINIINLLGCCSQGGPLWVIVEYAPHGNLKDFLKQNRPGAPQRRSDSD 822
Query: 788 ------PTAAT-------LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISD 834
P +T L A QIA GM+YL S +HRDLAARN L+ GY +KI+D
Sbjct: 823 GYLDDKPLISTQHLGEKELTKFAFQIARGMEYLASRRCIHRDLAARNVLVSDGYVMKIAD 882
Query: 835 FGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRP 894
FG + +YY+ + LP++W A ES+ KY ++SDVW++ V L EI + +P
Sbjct: 883 FGLARDIQDTEYYRKNTNGRLPIKWMAPESLQEKKYDSQSDVWSYGVLLWEIMTY-GDQP 941
Query: 895 YEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
Y H+ E L S+L M ++ C ++Y +M +CW + RPTF E+
Sbjct: 942 YPHILSAEEL--YSYLITGQRM----EKPAKCSLNIYVVMRQCWHFESCARPTFAEL 992
>UniRef50_UPI0000D56AE3 Cluster: PREDICTED: similar to CG1594-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG1594-PA - Tribolium castaneum
Length = 503
Score = 146 bits (354), Expect = 3e-33
Identities = 88/264 (33%), Positives = 134/264 (50%), Gaps = 13/264 (4%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALS 750
++ +G +G VY G EY G E R+VA+K L ++FER++ I+ L
Sbjct: 233 RIGQGFYGEVY----KGTLEYPGNPEIEPRIVAIKKLKSSTVSACLQDFEREINIMKTLQ 288
Query: 751 SPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGMQYLES 809
++ +LG R P +++V+E++ G L ++L+ LL A IA GM YL
Sbjct: 289 HRNIVEILGVSREPDISLVMEFVHHGSLQSYLKINRESLQIKQLLKFALDIAEGMNYLGK 348
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGK 869
N VHRDLA RN L+ +KISDFG T DYY + LP++W A ES+ GK
Sbjct: 349 KNIVHRDLATRNILVADENHVKISDFGLAQVIGTNDYYILKTNRELPIKWYAPESLRDGK 408
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN----LSHLQADDGMFECVDRAPG 925
++ +SDVW++ VT+ E+++ +L + EV L + F C P
Sbjct: 409 FSVRSDVWSYGVTMCEMFNWGEEPKLSNLGEEEVRGQEQQVLLNALESGARFPC---PPM 465
Query: 926 CPRDLY-ELMLECWRRDELDRPTF 948
CP+ +Y ++ CW D +RP F
Sbjct: 466 CPQAVYIRIIYPCWHADPHERPAF 489
Score = 45.2 bits (102), Expect = 0.009
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 9/73 (12%)
Query: 869 KYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPR 928
K +T +DVWAFA TL EI+ L E + + ++ + A C P C +
Sbjct: 22 KRSTAADVWAFATTLWEIFVLG-----EEIKTSDHVETM-RWYASGKRLPC---PPLCDK 72
Query: 929 DLYELMLECWRRD 941
D+Y+LMLECW D
Sbjct: 73 DIYDLMLECWNAD 85
>UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77;
Eutheria|Rep: Proto-oncogene c-fes variant 4 - Homo
sapiens (Human)
Length = 752
Score = 145 bits (352), Expect = 4e-33
Identities = 85/248 (34%), Positives = 135/248 (54%), Gaps = 10/248 (4%)
Query: 711 YNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVV 769
++G + ++ LVAVK + +F ++ RIL S P++ R++G C + P+ +V
Sbjct: 506 FSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIV 565
Query: 770 LEYLELGDLCAFLRA-AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGY 828
+E ++ GD FLR TLL + AAGM+YLES +HRDLAARNCL+ +
Sbjct: 566 MELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKN 625
Query: 829 QIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
+KISDFG E Y G +P++W A E++ G+Y+++SDVW+F + L E +S
Sbjct: 626 VLKISDFGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFS 685
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
L PY +L++ + + + G C + CP ++ LM +CW + RP+F
Sbjct: 686 L-GASPYPNLSNQQTREFVE----KGGRLPCPEL---CPDAVFRLMEQCWAYEPGQRPSF 737
Query: 949 GEIHLFLQ 956
I+ LQ
Sbjct: 738 STIYQELQ 745
>UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9;
Clupeocephala|Rep: C-Met receptor tyrosine kinase - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1382
Score = 144 bits (350), Expect = 8e-33
Identities = 89/240 (37%), Positives = 132/240 (55%), Gaps = 15/240 (6%)
Query: 718 EKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC---RSPPLAVVLEYLE 774
+K+ A+K L ++E +F ++ I+ S P++ +LG C PL VVL Y++
Sbjct: 1104 QKQHCAIKSLNRITDIEEVSQFLKEGIIVKDFSHPNVLSLLGICLPSEGSPL-VVLPYMK 1162
Query: 775 LGDLCAFLR-AAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKIS 833
GDL F+R + PT L+ Q+A GM+YL S FVHRDLAARNC++ + Y +K++
Sbjct: 1163 HGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLASKKFVHRDLAARNCMLDESYTVKVA 1222
Query: 834 DFGTDNEAYTCDYYKVDGR--VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCR 891
D G + Y +YY V + V LP++W A ES+ K+TTKSDVW+F V L E+ +
Sbjct: 1223 DVGLARDVYDKEYYSVHNKHGVKLPVKWMALESLQTHKFTTKSDVWSFGVLLWELMTR-G 1281
Query: 892 RRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
PY + ++ L LQ + + CP LY +M+ECW RPTF E+
Sbjct: 1282 APPYSDVNSFDITVFL--LQG-----RRLLQPEFCPDALYNVMIECWHPKPERRPTFLEL 1334
>UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|Rep:
Tyrosine kinase receptor - Xenopus laevis (African clawed
frog)
Length = 1369
Score = 144 bits (350), Expect = 8e-33
Identities = 97/274 (35%), Positives = 145/274 (52%), Gaps = 25/274 (9%)
Query: 684 HRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDV 743
HR R+I K G FG+VY V E ++ AVK L L+E EEF R+
Sbjct: 1058 HRDRIIGK---GHFGSVY--HGTYVDE-----DQQEVHCAVKSLNRITDLEEVEEFLREG 1107
Query: 744 RILAALSSPHLARVLGAC---RSPPLAVVLEYLELGDLCAFLRAAIP-PTAATLLHIATQ 799
++ + P++ ++G C PL VVL +++ GDL F+R+ PT L+ Q
Sbjct: 1108 ILMKSFHHPNVLSLIGICLPQEGLPL-VVLPFMKHGDLRHFIRSEERNPTVKDLVGFGLQ 1166
Query: 800 IAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV--DGRVPLPL 857
++ GM+YL + FVHRDLAARNC++ + + +K++DFG + + +YY V LP+
Sbjct: 1167 VSRGMEYLANRKFVHRDLAARNCMLDESFHVKVADFGLARDVFDKEYYSVRRHKNARLPV 1226
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
+W A ES+ K+TTKSDVW+F V L E+ + R P D + D +L +
Sbjct: 1227 KWMAMESLQTQKFTTKSDVWSFGVLLWEL--MTRGAP--PYPDVDAYDITRYLFRGRRLA 1282
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ CP LY LML CW ++RPTF ++
Sbjct: 1283 Q----PEYCPNPLYSLMLSCWNPQPVERPTFTQL 1312
>UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta
cDNA, RIKEN full-length enriched library,
clone:I530025O09 product:fibroblast growth factor
receptor 1, full insert sequence; n=18; Eumetazoa|Rep:
14 days pregnant adult female placenta cDNA, RIKEN
full-length enriched library, clone:I530025O09
product:fibroblast growth factor receptor 1, full insert
sequence - Mus musculus (Mouse)
Length = 386
Score = 144 bits (350), Expect = 8e-33
Identities = 99/290 (34%), Positives = 151/290 (52%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR RL + L EG FG V +AEA G+ + ++ VAVK L DAT K+ +
Sbjct: 36 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTK---VAVKMLKSDATEKDLSDL 92
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LGAC + PL V++EY G+L +L+A PP
Sbjct: 93 ISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPS 152
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
++ L+ A Q+A GM+YL S +HRDLAARN L+ + +KI+DFG +
Sbjct: 153 HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNALVTEDNVMKIADFGLARDI 212
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F V L EI++L PY +
Sbjct: 213 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL-GGSPYPGVPVE 271
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E+ L +G +D+ C +LY +M +CW RPTF ++
Sbjct: 272 ELFKLLK-----EG--HRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 314
>UniRef50_Q6TYB9 Cluster: Dauer abnormal formation-2 precursor; n=2;
Caenorhabditis briggsae|Rep: Dauer abnormal formation-2
precursor - Caenorhabditis briggsae
Length = 1807
Score = 144 bits (350), Expect = 8e-33
Identities = 100/303 (33%), Positives = 150/303 (49%), Gaps = 29/303 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK-EREE 738
E + + + + +G FG VY+A+ G AVK +A E
Sbjct: 1197 ELEKESVTLGEVIGQGTFGKVYLAQGKKCVSIRGDAFGP---CAVKINTEEAAESLENMN 1253
Query: 739 FERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRA-----AIPPTAAT 792
+ + ++ + + ++ G S P VV+E++ELG+L +LRA
Sbjct: 1254 YLMEANVMKNFKTTFIVKLFGVVSSVHPAWVVMEFMELGNLRDYLRAKREEEVFDENNCN 1313
Query: 793 LLHI---------ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
+I A QI GM YLESL F HRDLAARNC+I K +KI DFG + +
Sbjct: 1314 FYNIVPREKICEWAAQICDGMAYLESLKFCHRDLAARNCMIDKTELVKIGDFGMARDLFY 1373
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
DYYK G+ +P+RW + ES+ GK+ +KSD+W+F V L+E+ +L +PY L++ EV
Sbjct: 1374 HDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDIWSFGVVLYELITL-GAQPYIGLSNDEV 1432
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDL-YELMLECWRRDELDRPTFGE-IHLFLQRKSLN 961
L+ + GM V + P C + Y++M CWR DRPTF + +HL S
Sbjct: 1433 LNYI-------GMARKVIKKPDCCSEYWYKIMKMCWRYAPRDRPTFLQLVHLLSAEASEE 1485
Query: 962 YAT 964
+ T
Sbjct: 1486 FKT 1488
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 144 bits (349), Expect = 1e-32
Identities = 91/268 (33%), Positives = 136/268 (50%), Gaps = 16/268 (5%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATL-KEREEFERDVRILAAL 749
+L G FGTV + GV Y + A+K+L L ++ E R+ +AAL
Sbjct: 291 ELGAGTFGTVRL----GV--YRPKNGEPEVQCALKYLKQSEELPNQKAEILREADAMAAL 344
Query: 750 SSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQIAAGMQYLES 809
++ R+ G C P+ +V+E G L FLR +L++A Q++ GM YLE
Sbjct: 345 DHCNIVRLFGICVGDPICLVMELARQGPLNKFLRKRPTFPVIKILNMALQVSRGMAYLEE 404
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWAAWESVLRG 868
+ FVHRDLAARN L+ +KISDFG +YYK + PL+W A E +
Sbjct: 405 VRFVHRDLAARNVLVVDDDNVKISDFGMSRAIGAGSEYYKAETAGRWPLKWYAPECIYYA 464
Query: 869 KYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPR 928
K+ +KSDVW++ VT+ E +S +PY L +++ L Q +D CP+
Sbjct: 465 KFDSKSDVWSYGVTVWEAFSF-GAKPYAGLKGQDIMQMLEGNQR-------LDSPEKCPQ 516
Query: 929 DLYELMLECWRRDELDRPTFGEIHLFLQ 956
+Y++ML CW DRP+F E+ L+
Sbjct: 517 PIYDIMLRCWAWRPEDRPSFSELSSMLK 544
>UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 624
Score = 144 bits (349), Expect = 1e-32
Identities = 111/331 (33%), Positives = 164/331 (49%), Gaps = 38/331 (11%)
Query: 642 GTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVY 701
G+ S P +R + T S S +E LD L E R ++ + +L EGAFG V
Sbjct: 292 GSANSSTPLIRYRNVTTS-SIEESFLDFYE-LPIDEDWEIDRSQITIKEQLGEGAFGLVM 349
Query: 702 VAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS-PHLARVLGA 760
AEA G+ + + VAVK L DAT E + ++ + + S ++ ++GA
Sbjct: 350 KAEALGLTDM-----PYRHTVAVKMLKADATENELADLLSEMDTMKNIGSHKNIINLIGA 404
Query: 761 C-RSPPLAVVLEYLELGDLCAFLRAAIP---------------PTAAT--LLHIATQIAA 802
C ++ PL VV+E+ G+L FLR P P+ + A QIA
Sbjct: 405 CTQNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQPSLIVRDFISFAFQIAR 464
Query: 803 GMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK--VDGRVPLPLRWA 860
GM+YL +HRDLAARN L+G+ Y +KI+DFG DYY+ DGR LP++W
Sbjct: 465 GMEYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGR--LPIKWL 522
Query: 861 AWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECV 920
A E++ YTT+SDVW F + L EI++L PY + ++ L L +
Sbjct: 523 AIEALFDRVYTTQSDVWTFGILLWEIFTL-GGSPYPGIP----VEKLFELLKSGYRMQMP 577
Query: 921 DRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ CP +Y++ML CW + RP+F E+
Sbjct: 578 QK---CPDKMYDIMLSCWNENPNARPSFTEL 605
>UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12;
Euarchontoglires|Rep: Uncharacterized protein LTK - Homo
sapiens (Human)
Length = 803
Score = 144 bits (349), Expect = 1e-32
Identities = 96/285 (33%), Positives = 145/285 (50%), Gaps = 24/285 (8%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKERE 737
V E + ++ L GAFG VY G+P + + VA+K L + ++
Sbjct: 441 VTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQ-----VAIKTLPELCSPQDEL 495
Query: 738 EFERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT 792
+F + I++ ++ R +G + R+ P ++LE + GD+ +FLR + P P+
Sbjct: 496 DFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLV 555
Query: 793 ---LLHIATQIAAGMQYLESLNFVHRDLAARNCLI---GKGYQIKISDFGTDNEAYTCDY 846
LL +A IA G YLE +F+HRD+AARNCL+ G KI DFG + Y Y
Sbjct: 556 MRDLLQLAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASY 615
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
Y+ R LP++W E+ L G +T+K+D W+F V L EI+SL PY T+ EVLD
Sbjct: 616 YRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSL-GYMPYPGRTNQEVLD- 673
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G +D GCP +Y +M +CW+ + RP+F I
Sbjct: 674 ---FVVGGGR---MDPPRGCPGPVYRIMTQCWQHEPELRPSFASI 712
>UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor 1
precursor; n=310; Euteleostomi|Rep: Basic fibroblast
growth factor receptor 1 precursor - Homo sapiens
(Human)
Length = 822
Score = 144 bits (349), Expect = 1e-32
Identities = 99/290 (34%), Positives = 151/290 (52%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR RL + L EG FG V +AEA G+ + ++ VAVK L DAT K+ +
Sbjct: 472 ELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTK---VAVKMLKSDATEKDLSDL 528
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LGAC + PL V++EY G+L +L+A PP
Sbjct: 529 ISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPS 588
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
++ L+ A Q+A GM+YL S +HRDLAARN L+ + +KI+DFG +
Sbjct: 589 HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDI 648
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F V L EI++L PY +
Sbjct: 649 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL-GGSPYPGVPVE 707
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E+ L +G +D+ C +LY +M +CW RPTF ++
Sbjct: 708 ELFKLLK-----EG--HRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQL 750
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 144 bits (348), Expect = 1e-32
Identities = 90/266 (33%), Positives = 143/266 (53%), Gaps = 21/266 (7%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILA 747
++ K+ G FG VY A+ +S+ LVAVK +++ +F ++ RIL
Sbjct: 933 LLDKIGRGNFGDVYKAKLK---------SSKNTLVAVKTCRMTLPEEQKRKFLQEGRILK 983
Query: 748 ALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA-AIPPTAATLLHIATQIAAGMQ 805
P++ +++G C + P+ +V+E + G L FLR A ++ + AAGM+
Sbjct: 984 QYDHPNIVKLIGICVQKQPIMIVMELVAGGSLLMFLRKNASTLGQRQMMGMCRDAAAGMR 1043
Query: 806 YLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESV 865
YLES N +HRDLAARNCLIG +KISDFG E +Y G +P++W A E++
Sbjct: 1044 YLESKNCIHRDLAARNCLIGSENIVKISDFGMSREEE--EYIVSGGMKQIPIKWTAPEAL 1101
Query: 866 LRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPG 925
GKYT+ DVW++ + + EI+S PY ++ ++++ + D+G + G
Sbjct: 1102 NFGKYTSLCDVWSYGILVWEIFSR-GDTPYSGMS-----NSMARERIDEGY--RMPAPEG 1153
Query: 926 CPRDLYELMLECWRRDELDRPTFGEI 951
P ++Y LML+CW + RP F EI
Sbjct: 1154 APPEMYRLMLKCWSYEPESRPHFDEI 1179
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 144 bits (348), Expect = 1e-32
Identities = 90/271 (33%), Positives = 145/271 (53%), Gaps = 24/271 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E + +++++ +L G FG V+ +G+ +NG + VAVK L T+ EEF
Sbjct: 234 EIEKTQIKLLRRLGAGQFGEVW----EGL--WNGTTS-----VAVKTL-KPGTMSV-EEF 280
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHIA 797
++ I+ L P L ++ C + P+ +V E ++ G L +LR L+ +A
Sbjct: 281 LQEASIMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGSLLEYLRGEDGVLKIEQLVDVA 340
Query: 798 TQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPL 857
Q+A+GM YLE N++HRDLAARN L+G+ K++DFG + Y+ P+
Sbjct: 341 AQVASGMSYLEQQNYIHRDLAARNILVGEHGICKVADFGL-ARVIDEEIYEAHTGAKFPI 399
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
+W A E+ + ++T KSDVW+F V L+EI + R PY +T+ EVL+ + +
Sbjct: 400 KWTAPEAAMYNRFTIKSDVWSFGVVLYEIITY-GRFPYPGMTNPEVLEKIQ----QNYRM 454
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
C CP+ +++ML+CWR D RPTF
Sbjct: 455 PC---PANCPKQFHDIMLDCWREDPASRPTF 482
>UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:
ENSANGP00000013218 - Anopheles gambiae str. PEST
Length = 861
Score = 143 bits (347), Expect = 2e-32
Identities = 106/300 (35%), Positives = 144/300 (48%), Gaps = 34/300 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR L + + L EG FG V A +PE G T VAVK L A E
Sbjct: 481 EFPRTNLILDATLGEGEFGKVLKGFATDLPEKPGITT-----VAVKMLKTGANSVELLAL 535
Query: 740 ERDVRILAALSSPHLARVLGACRS--PPLAVVLEYLELGDLCAFLR-------------- 783
+ ++L ++ P++ R+LGAC PL +++EY + G L +LR
Sbjct: 536 LSEYQLLQEVNHPNVIRLLGACTKGDSPL-LIIEYCQYGSLKNYLRLSRKLEVLNADYEN 594
Query: 784 AAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
A P T +L A QI+ GM YL + VHRDLAARN L+ +G KISDFG + Y
Sbjct: 595 AVEPITVKDILSFAWQISKGMAYLTDIKLVHRDLAARNVLLAEGKVCKISDFGLTRDVYE 654
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
D Y + +P++W A ES+ YTTKSDVWAF V E+ +L PY +
Sbjct: 655 DDAYLKKSKDRVPVKWMAPESLADHIYTTKSDVWAFGVLCWELITL-GASPYPGIPP--- 710
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF----GEIHLFLQRKS 959
NL +L EC C ++Y ++ CW D RP+F G+ L L R +
Sbjct: 711 -QNLYNLLKQGYRMEC---PKNCSEEIYGIVRLCWADDPKQRPSFKHLAGQFELLLGRSA 766
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 142 bits (344), Expect = 4e-32
Identities = 94/277 (33%), Positives = 144/277 (51%), Gaps = 24/277 (8%)
Query: 675 TTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK 734
+T+ E P+ ++ ++L G F VY +G + + VA+K L ++ L
Sbjct: 237 STDEWELPKEEFQLENQLGSGHFADVY----------SGKWKNHSK-VAIKILKNNDALV 285
Query: 735 EREEFERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPPTAA-- 791
RE F+ +V+I+ L HL + C S P ++ E +E GDL FLR +
Sbjct: 286 LRE-FQLEVQIMKRLRHKHLISLFAVCTSSSPFYIITELIEKGDLLHFLRNPEGRSLQME 344
Query: 792 TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDG 851
+L+ +A Q+A GM YLE+ N +HRDLAARN L+G GY KI+DFG Y D
Sbjct: 345 SLIDMAAQVADGMAYLEANNSIHRDLAARNVLVGDGYVCKIADFGLARIIKEPVYLSDDK 404
Query: 852 RVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQ 911
++ P +W A E++ G Y++KSDVW+F + L+EI + PY + EV D ++
Sbjct: 405 KI--PYKWTAPEAIGHGTYSSKSDVWSFGILLYEIVT-HGGIPYPGVNTGEVYDLITKEN 461
Query: 912 ADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ P CP+ +Y +M CWR + +DRP F
Sbjct: 462 YR------MPSPPKCPQAIYNIMRACWRIESVDRPNF 492
>UniRef50_O16131 Cluster: Insulin receptor homolog precursor; n=2;
Caenorhabditis elegans|Rep: Insulin receptor homolog
precursor - Caenorhabditis elegans
Length = 1846
Score = 142 bits (344), Expect = 4e-32
Identities = 97/283 (34%), Positives = 142/283 (50%), Gaps = 28/283 (9%)
Query: 694 EGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPH 753
EG+FG VY+ + V G A+K D E + + I+ +
Sbjct: 1254 EGSFGKVYLGTGNNVVSLMGDRFGP---CAIKINVDDPASTENLNYLMEANIMKNFKTNF 1310
Query: 754 LARVLGACRS-PPLAVVLEYLELGDLCAFLRA-----AIPPTAATLLHI---------AT 798
+ ++ G + P VV+E ++LG+L +LR+ T I A
Sbjct: 1311 IVQLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNETDCNFFDIIPRDKFHEWAA 1370
Query: 799 QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLR 858
QI GM YLESL F HRDLAARNC+I + +KI DFG + + DYYK G+ +P+R
Sbjct: 1371 QICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARDLFYHDYYKPSGKRMMPVR 1430
Query: 859 WAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFE 918
W + ES+ GK+ +KSDVW+F V L+E+ +L +PY L++ EVL+ + GM
Sbjct: 1431 WMSPESLKDGKFDSKSDVWSFGVVLYEMVTL-GAQPYIGLSNDEVLNYI-------GMAR 1482
Query: 919 CVDRAPGCPRDL-YELMLECWRRDELDRPTFGE-IHLFLQRKS 959
V + P C + Y++M CWR DRPTF + +HL S
Sbjct: 1483 KVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLVHLLAAEAS 1525
>UniRef50_UPI00015B6363 Cluster: PREDICTED: similar to tyrosine
protein kinase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to tyrosine protein kinase - Nasonia vitripennis
Length = 1126
Score = 142 bits (343), Expect = 5e-32
Identities = 88/277 (31%), Positives = 147/277 (53%), Gaps = 20/277 (7%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALS 750
++ +G +G VY+ G+ E + +E + VAVK L A + +FER++ I+ L
Sbjct: 842 RIGQGFYGEVYL----GICEKDSVKDAEPQQVAVKKLKMRALEADLRDFEREIEIMKTLK 897
Query: 751 SPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQYLES 809
P++ +LG P + +V+E+++ G L ++L T LL A IA GM+YL
Sbjct: 898 HPNVVGILGVISEPEVCLVMEFVKHGSLQSYLAIHRESLTNKRLLGFALDIATGMEYLGR 957
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGK 869
+N VHRDLAARN L+ ++KISDFG DYY + LP++W A ES+ GK
Sbjct: 958 MNIVHRDLAARNILVADDNRVKISDFGLAQVTGKNDYYILQTNRDLPIKWYAPESLRDGK 1017
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD------NLSHLQADDG--MFECVD 921
++ +SDVW+F VT++E +S V++ ++ L+ + G + + ++
Sbjct: 1018 FSPRSDVWSFGVTMYETFSFGEDPKLPEFGSNSVVEVEGSGKAVNTLEEEGGADLLKALE 1077
Query: 922 R-----APG-CPRDLY-ELMLECWRRDELDRPTFGEI 951
R P CP+++Y ++M CW +RP F ++
Sbjct: 1078 RGARLPCPATCPQEVYTKVMYPCWNIQSHERPEFAKL 1114
Score = 54.8 bits (126), Expect = 1e-05
Identities = 64/227 (28%), Positives = 98/227 (43%), Gaps = 32/227 (14%)
Query: 715 ITSEKRL-VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYL 773
+T KRL A+K L D + +EF + + L S L R+ G +P + ++LE +
Sbjct: 493 VTKGKRLETAIKLLKEDEG-QPTKEFLKLAQKWGQLRSSALVRLYGVTLAPSVGMLLELV 551
Query: 774 ELGDLCAFLRAAIPPTAAT--LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIK 831
+LG L A+LR P T T ++ A +A + +LE VH ++ R L I
Sbjct: 552 KLGALDAYLRNNSPQTIKTVDMVEAAACLATAVWHLEENGVVHGNIRCRKLLNYSILVIF 611
Query: 832 ISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCR 891
+S E Y G L R + ++DVWA A TL EI+S
Sbjct: 612 LSVHWLPPECY--------GNPDLARR------------SIQADVWAIATTLWEIFSRGT 651
Query: 892 RRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECW 938
P ++ E D + A + GCP ++Y+LM +CW
Sbjct: 652 ILP----SNTEP-DPIKKFYASGKRLPIPN---GCPPEVYKLMTDCW 690
>UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to
ENSANGP00000019144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000019144 - Nasonia
vitripennis
Length = 1220
Score = 142 bits (343), Expect = 5e-32
Identities = 100/287 (34%), Positives = 150/287 (52%), Gaps = 31/287 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR +LR+ + L EG FG V+ AEAD + + G RLVAVK + A+ +E+E+
Sbjct: 916 EFPRDKLRLQTVLGEGNFGQVWKAEADDLTGHQGTT----RLVAVKTVKEGASDREKEDL 971
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA------------- 784
R++ I+ + S P++ +LG C P ++LEY+ G L A+LR
Sbjct: 972 VRELEIMQRVGSHPNVVTLLGCCTEQEPHYLILEYVMYGKLLAYLRDHRTRQDFYNFSED 1031
Query: 785 AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTC 844
+ T+ L +A GM+YL S +HRDLAARN L+ KI+DFG A
Sbjct: 1032 SAALTSRDLTVFGYCVARGMEYLASKKIIHRDLAARNVLVDHNKLCKIADFGMSRFANE- 1090
Query: 845 DYYKVD---GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
D ++ GR LP+RW A ES++ +TTK+DVW+F + + EI +L PY +T
Sbjct: 1091 DGEVIETRHGRNALPIRWMAPESLIYSLFTTKTDVWSFGILMWEIVTL-GSTPYPDMTAR 1149
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
EV+ ++ G ++R C +L+ ++ CW D RP F
Sbjct: 1150 EVMRSV-----QSGY--RLERPSHCRSELFRVIARCWHADPDRRPEF 1189
>UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7223-PA, isoform A - Tribolium castaneum
Length = 861
Score = 142 bits (343), Expect = 5e-32
Identities = 105/293 (35%), Positives = 150/293 (51%), Gaps = 35/293 (11%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR L + L EGAFG V AEA G+ + GA + +VAVK L T E +
Sbjct: 527 EIPRSMLCLGKSLGEGAFGKVVKAEAVGLLK-PGASS----IVAVKMLKEGHTDNEMMDL 581
Query: 740 ERDVRILAALSSPH-LARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + + + +LG C + PL VV+EY G+L FLR P
Sbjct: 582 VSEMEMMKMIGKHNNIINLLGCCTQGGPLYVVVEYAPYGNLRDFLRQHRPSSGYEPAIGL 641
Query: 789 --------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
T L+ A Q+A GM+YL S +HRDLAARN L+ Y +KI+DFG +
Sbjct: 642 EEKEKKTLTQKDLVSFAYQVARGMEYLASRRCIHRDLAARNVLVSDDYFLKIADFGLARD 701
Query: 841 AYTCDYYK--VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
+ DYY+ DGR LP++W A E++ YTT+SDVW++ + L EI +L PY +
Sbjct: 702 IHCNDYYRKTTDGR--LPVKWMAPEALFHRVYTTQSDVWSYGILLWEIMTL-GGTPYPSV 758
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E L L L+ M ++ P C ++Y LM ECW +RPTF ++
Sbjct: 759 PSVEKLFQL--LRNGHRM----EKPPCCSLEIYMLMRECWSYKPNERPTFSQL 805
>UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14764,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 635
Score = 142 bits (343), Expect = 5e-32
Identities = 102/292 (34%), Positives = 151/292 (51%), Gaps = 29/292 (9%)
Query: 678 VIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKERE 737
V E PR RL + L EG FG V +AEA G+ + A ++ VAVK L DAT K+R
Sbjct: 340 VWELPRDRLTLGKPLGEGCFGQVVLAEAVGLDKNKPARVTK---VAVKMLKADATEKDRA 396
Query: 738 EFERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP-------- 787
+ ++ ++ + ++ +LGAC + PL V++EY G+L +LRA P
Sbjct: 397 DLISEMEMMKMIGKHKNIINLLGACTQDGPLYVLVEYASKGNLRDYLRARRPAGLEYWSS 456
Query: 788 --PTAATLLHI------ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
P + + I A Q+A GM YL S +HRDLAARN L+ + +KI+DFG
Sbjct: 457 SRPVSLASMEIMELVSAAYQVARGMAYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR 516
Query: 840 EAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
+ + DYYK LP++W A E++ YT +SDVW+F V L EI++L PY +
Sbjct: 517 DVHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL-GGSPYPGVP 575
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ L L + E + P ++LY +M CW RPTF ++
Sbjct: 576 ----VEELFKLLKEGHRME---KPPTSTQELYLMMRGCWHAVPARRPTFQQL 620
>UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1;
Geodia cydonium|Rep: Tyrosine-protein kinase receptor -
Geodia cydonium (Sponge)
Length = 570
Score = 142 bits (343), Expect = 5e-32
Identities = 90/290 (31%), Positives = 149/290 (51%), Gaps = 32/290 (11%)
Query: 685 RLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVR 744
+L + L EGAFG VY + + + VA+K L + + + F ++
Sbjct: 268 QLILTESLGEGAFGRVYKGSMKTGDDDDRTVE-----VAIKTLKDISQQENIDNFVQESI 322
Query: 745 ILAALSSPHLARVLGACRSP----PLAVVLEYLELGDLCAFLRAAIPPTAAT-------- 792
++ + P++ +LG C PL +VL ++ GDL ++L + P+ T
Sbjct: 323 LMLGFNHPNVLELLGVCFDTTDRHPL-IVLPFMANGDLRSYLMSKRDPSVTTKFTHFPQG 381
Query: 793 -----LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
L + ++A GM+YL + +FVHRDLAARNC++ ++++DFG + Y+ DYY
Sbjct: 382 LDEERALVMCLEVARGMEYLSNSSFVHRDLAARNCMVSGELTVRVADFGLSRDVYSKDYY 441
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
++ + LP++W A ES+ +T KSDVW+F V E++SL PY + + E+ D +
Sbjct: 442 RMGTKTMLPVKWMAPESLADNIFTVKSDVWSFGVVCWEVFSLV--APYPGIGNHEMSDYI 499
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
G + R CPR++YELM +CW + RP F E+ L+R
Sbjct: 500 G-----GGRRLKIPRL--CPREIYELMEQCWNEESNKRPNFSELVSQLER 542
>UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|Rep:
Focal adhesion kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 1092
Score = 141 bits (342), Expect = 7e-32
Identities = 83/231 (35%), Positives = 122/231 (52%), Gaps = 10/231 (4%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
VAVK DA L E+F + I+ PH+ +++G C P+ +V+E LG+L A+
Sbjct: 485 VAVKTCKADADLATSEKFLEEAYIMQKFEHPHIIKLIGICSGSPIWIVMELARLGELRAY 544
Query: 782 LRA-AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
L+ TLL + Q++ + YLES FVHRD+AARN L+ IK++DFG
Sbjct: 545 LKKNGSKLKLGTLLLYSYQLSTALSYLESKKFVHRDIAARNVLVSSPTCIKLADFGLSRW 604
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
YY + LP++W A ES+ ++TT SDVW F V EI L +P++ + +
Sbjct: 605 VEDQSYY-TSTKGMLPIKWMAPESINFRRFTTASDVWMFGVCTWEILML-GVKPFQGIKN 662
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
C+V+ L ++G E + P CP LY LM +CW + RP F I
Sbjct: 663 CDVIGKL-----ENG--ERLPLPPNCPPRLYSLMSQCWSYEPHKRPNFKNI 706
>UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precursor;
n=81; Tetrapoda|Rep: Hepatocyte growth factor receptor
precursor - Homo sapiens (Human)
Length = 1390
Score = 141 bits (342), Expect = 7e-32
Identities = 88/235 (37%), Positives = 125/235 (53%), Gaps = 15/235 (6%)
Query: 723 AVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC---RSPPLAVVLEYLELGDLC 779
AVK L + E +F + I+ S P++ +LG C PL VVL Y++ GDL
Sbjct: 1108 AVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPL-VVLPYMKHGDLR 1166
Query: 780 AFLRAAIP-PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
F+R PT L+ Q+A GM+YL S FVHRDLAARNC++ + + +K++DFG
Sbjct: 1167 NFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLA 1226
Query: 839 NEAYTCDYYKVDGR--VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ Y +YY V + LP++W A ES+ K+TTKSDVW+F V L E+ + R P
Sbjct: 1227 RDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWEL--MTRGAP-- 1282
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D D +L + + CP LYE+ML+CW RP+F E+
Sbjct: 1283 PYPDVNTFDITVYLLQGRRLLQ----PEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47;
Euteleostomi|Rep: Protein tyrosine kinase 2 beta - Homo
sapiens (Human)
Length = 1009
Score = 141 bits (342), Expect = 7e-32
Identities = 97/264 (36%), Positives = 133/264 (50%), Gaps = 23/264 (8%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EG FG VY +GV Y EK VAVK D TL +E+F + I+ L
Sbjct: 431 LGEGFFGEVY----EGV--YTNH-KGEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDH 483
Query: 752 PHLARVLGACRSPPLAVVLEYLELGDLCAFL-RAAIPPTAATLLHIATQIAAGMQYLESL 810
PH+ +++G P +++E G+L +L R TL+ + QI M YLES+
Sbjct: 484 PHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLESI 543
Query: 811 NFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKY 870
N VHRD+A RN L+ +K+ DFG DYYK LP++W + ES+ ++
Sbjct: 544 NCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEDYYKA-SVTRLPIKWMSPESINFRRF 602
Query: 871 TTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPG---CP 927
TT SDVW FAV + EI S ++P+ L + +V+ G+ E DR P CP
Sbjct: 603 TTASDVWMFAVCMWEILSF-GKQPFFWLENKDVI----------GVLEKGDRLPKPDLCP 651
Query: 928 RDLYELMLECWRRDELDRPTFGEI 951
LY LM CW D DRP F E+
Sbjct: 652 PVLYTLMTRCWDYDPSDRPRFTEL 675
>UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberites
domuncula|Rep: Receptor tyrosine kinase - Suberites
domuncula (Sponge)
Length = 715
Score = 141 bits (341), Expect = 9e-32
Identities = 100/309 (32%), Positives = 158/309 (51%), Gaps = 23/309 (7%)
Query: 650 SVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVP 709
S S +T P + + R+L + + P H L + L GAFG V AE
Sbjct: 351 SHHSDSTTSDPLGDNGCITMSRKLAVADGVFVPFHLLNLKDDLGSGAFGVVKKAELFD-- 408
Query: 710 EYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSP-HLARVLGAC-RSPPLA 767
I+ +VAVK L A+ ++ ++ ++++L + ++ LGA L
Sbjct: 409 ----PISQTTSIVAVKMLKESASTEDEKDIIMELKVLYHVGEHCNVVSFLGASVHKGKLH 464
Query: 768 VVLEYLELGDLCAFLRAA-----IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNC 822
+++EY E G+L FLR+ P + + IA+Q+A GM YL S +HRDLAARN
Sbjct: 465 LIVEYCERGNLLQFLRSKRGDMKSPLSVQNQVAIASQVANGMAYLASKRCIHRDLAARNV 524
Query: 823 LIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVT 882
LI K +K++DFG + Y+ Y+ G+ LP++W A E +L G T+KSDVW+F +
Sbjct: 525 LITKDLTLKVADFGLARKMYS-SVYRPSGK-RLPIKWMAPEGILDGVCTSKSDVWSFGIL 582
Query: 883 LHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDE 942
L EI +L R PY + V+ ++ ++G + + GCP LY +M CW+ +
Sbjct: 583 LWEIMTL-GRTPYPGRSAHWVIRDI-----ENGY--RMPQPDGCPDKLYSVMKCCWQMNP 634
Query: 943 LDRPTFGEI 951
+ RP F E+
Sbjct: 635 IARPEFTEL 643
>UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor a - Nematostella vectensis
Length = 441
Score = 141 bits (341), Expect = 9e-32
Identities = 108/329 (32%), Positives = 161/329 (48%), Gaps = 37/329 (11%)
Query: 644 RRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVA 703
R + V S+ + S +E LD L E R ++ + +L EGAFG V A
Sbjct: 78 RSRFSSGVSSRLDSSSVITEESFLDFYE-LPIDEDWEIDRSQITIKEQLGEGAFGLVMKA 136
Query: 704 EADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS-PHLARVLGAC- 761
EA G+ + + VAVK L DAT E + ++ + + S ++ ++GAC
Sbjct: 137 EALGLTDM-----PYRHTVAVKMLKADATENELADLLSEMDTMKNIGSHKNIINLIGACT 191
Query: 762 RSPPLAVVLEYLELGDLCAFLRAAIP---------------PTAAT--LLHIATQIAAGM 804
++ PL VV+E+ G+L FLR P P+ + A QIA GM
Sbjct: 192 QNGPLYVVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQPSLIVRDFISFAFQIARGM 251
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK--VDGRVPLPLRWAAW 862
+YL +HRDLAARN L+G+ Y +KI+DFG DYY+ DGR LP++W A
Sbjct: 252 EYLSFKKCIHRDLAARNILVGEDYVMKIADFGLARNVRDMDYYRKATDGR--LPIKWLAI 309
Query: 863 ESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDR 922
E++ YTT+SDVW F + L EI++L PY + ++ L L + +
Sbjct: 310 EALFDRVYTTQSDVWTFGILLWEIFTL-GGSPYPGIP----VEKLFELLKSGYRMQMPQK 364
Query: 923 APGCPRDLYELMLECWRRDELDRPTFGEI 951
CP +Y++ML CW + RP+F E+
Sbjct: 365 ---CPDKMYDIMLSCWNENPNARPSFTEL 390
>UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12;
Eumetazoa|Rep: Tyrosine-protein kinase Fps85D -
Drosophila melanogaster (Fruit fly)
Length = 1325
Score = 141 bits (341), Expect = 9e-32
Identities = 88/267 (32%), Positives = 140/267 (52%), Gaps = 22/267 (8%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILA 747
++ ++ G FG VY A+ + S K VAVK +++ +F ++ RIL
Sbjct: 1065 LLERIGRGNFGDVYKAK----------LKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILK 1114
Query: 748 ALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA-AIPPTAATLLHIATQIAAGMQ 805
P++ +++G C + P+ +V+E + G L +LR + T + + AAGM+
Sbjct: 1115 QYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMR 1174
Query: 806 YLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESV 865
YLES N +HRDLAARNCL+ + +KISDFG E +Y DG +P++W A E++
Sbjct: 1175 YLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEE--EYIVSDGMKQIPVKWTAPEAL 1232
Query: 866 LRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPG 925
GKYT+ DVW++ + + EI+S PY +T+ + + D G +
Sbjct: 1233 NFGKYTSLCDVWSYGILMWEIFSK-GDTPYSGMTNSRARERI-----DTGY--RMPTPKS 1284
Query: 926 CPRDLYELMLECWRRDELDRPTFGEIH 952
P ++Y LML+CW D RP F EI+
Sbjct: 1285 TPEEMYRLMLQCWAADAESRPHFDEIY 1311
>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 510
Score = 140 bits (340), Expect = 1e-31
Identities = 91/285 (31%), Positives = 141/285 (49%), Gaps = 26/285 (9%)
Query: 675 TTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK 734
T N E P+ + +L +G F VY + G+ VA+K L +D+
Sbjct: 232 TVNDWELPKEEFTLEEELGKGFFADVYRGKWKGMVN-----------VAIKILKNDSI-- 278
Query: 735 EREEFERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRAAIPP--TAA 791
EF + +IL L HL + C S P ++ E +E GDL + L+ A
Sbjct: 279 NHREFMLETQILKKLRHKHLIALFAVCTSSSPFYIITELMEKGDLLSLLKGKEGQDLNAQ 338
Query: 792 TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDG 851
L +A+Q+A GM YLE N +HRDLAARN L+G Y K++D G Y D
Sbjct: 339 MLTEMASQVADGMAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVKESVYSSEDA 398
Query: 852 RVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQ 911
++ P +W+A E++ G+++ KSDVW+F V L+E+++ PY ++ EV + ++
Sbjct: 399 QI--PYKWSAPEAISHGRFSNKSDVWSFGVLLYEMFTY-GGVPYPAFSNIEVYNMIT--- 452
Query: 912 ADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
G + P CP +Y++ML CWR +RP F E+ L+
Sbjct: 453 --SGY--RMPAPPNCPSHIYDIMLMCWRYSAEERPDFSELLRLLE 493
>UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
KLG - Strongylocentrotus purpuratus
Length = 1013
Score = 140 bits (340), Expect = 1e-31
Identities = 87/292 (29%), Positives = 153/292 (52%), Gaps = 25/292 (8%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
++FP+H ++ I+ + GA+G V ++ A G+ + A T + + K + +L+ +
Sbjct: 731 LQFPKHDMQTITTIGHGAYGEVTLSRAAGIKDGEEATTVMVKALETK----EESLQL--D 784
Query: 739 FERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAA--------IPP- 788
F R++ +L L+ ++ ++LG CR + P ++ EYL+ GDL FL+A +PP
Sbjct: 785 FRREIEMLGKLNHENIVKLLGVCRDTEPQLMITEYLDWGDLKQFLQATRGENGTKNVPPP 844
Query: 789 -TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
T + + I Q+A GM+ L + F+H DLAARNCL+ ++KI + Y +Y+
Sbjct: 845 LTLSQKIDIVNQVALGMETLSANRFIHGDLAARNCLLSPSMEVKICTMSVSQDLYRPEYH 904
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNL 907
+ ++ +P+RW E++ + + KSDVWA+ + + E++S PY L + V+ +
Sbjct: 905 EYHQKL-IPVRWMPAEAIFEDELSAKSDVWAYGIFVWEVFSQ-GTLPYTQLDNDAVMRAM 962
Query: 908 SHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKS 959
DG ++ P P ++ +M CW DR TF EI L R S
Sbjct: 963 I-----DGEL-MLETPPDTPEEIELMMHRCWADSPKDRHTFSEITHHLGRIS 1008
>UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1;
Tetraodon nigroviridis|Rep: Tyrosine-protein kinase
receptor - Tetraodon nigroviridis (Green puffer)
Length = 1419
Score = 140 bits (340), Expect = 1e-31
Identities = 73/165 (44%), Positives = 100/165 (60%), Gaps = 8/165 (4%)
Query: 787 PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
PPT ++ +A +IA GM YL + FVHRDLAARNC++G + +KI DFG + Y DY
Sbjct: 1166 PPTLKEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVGHDFTVKIGDFGMTRDIYETDY 1225
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
Y+ G+ LP+RW A ES+ G +T SD W+F V L EI +L +PY+ L++ +VL
Sbjct: 1226 YRKGGKGLLPVRWMAPESLKDGVFTAHSDCWSFGVVLWEISTL-SEQPYQGLSNEQVLKF 1284
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ DG + +DR CP LY LM CW+ + RPTF EI
Sbjct: 1285 VM-----DGGY--LDRPDNCPDRLYNLMQMCWQYNPKMRPTFLEI 1322
Score = 42.7 bits (96), Expect = 0.046
Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ ++ +L +G FG VY A + + G + VAVK + A L++R EF
Sbjct: 1004 EVPREKISILRELGQGTFGMVYEGLAKDIIKGEG-----ETHVAVKTVNESANLRQRIEF 1058
Query: 740 ERDVRILAALSSPHLARVLGACRSPP 765
+ ++ A S H+ V G PP
Sbjct: 1059 LNEASVMKAFSCHHV--VSGNANGPP 1082
>UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep:
Zgc:154019 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 732
Score = 140 bits (340), Expect = 1e-31
Identities = 92/262 (35%), Positives = 137/262 (52%), Gaps = 16/262 (6%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALS 750
+L G+FG V AE P T VAVK L + +F ++V + +L
Sbjct: 116 RLGSGSFGVVRKAEWH-TP------TGRVLPVAVKTL-RSGQVDLVSDFLQEVTSMQSLD 167
Query: 751 SPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHI-ATQIAAGMQYLES 809
P++ + G + PL +V E LG L LR + L + +TQIAAGM+YLES
Sbjct: 168 HPNIIHLYGVVLTHPLKMVTELAPLGSLYDTLRLRHGEYPLSRLWLFSTQIAAGMEYLES 227
Query: 810 LNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGK 869
F+HRDLAARN L+ Q+KI DFG D+Y + +P W A ES+ G
Sbjct: 228 RRFIHRDLAARNVLLAAREQVKIGDFGLMRGLDDRDHYIMTAHRRIPFAWCAPESLRTGS 287
Query: 870 YTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRD 929
++ SDVW F VTL E+++ C P+ L+ ++L + +G E ++R P CP++
Sbjct: 288 FSHASDVWMFGVTLWEMFTYC-EEPWLGLSGRQILYRVER----EG--ERLERPPDCPQE 340
Query: 930 LYELMLECWRRDELDRPTFGEI 951
LY +M +CW + +RPTF ++
Sbjct: 341 LYAVMRKCWACNSTERPTFAQL 362
>UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56;
n=15; Sophophora|Rep: Focal adhesion kinase homolog
DFak56 - Drosophila melanogaster (Fruit fly)
Length = 1200
Score = 140 bits (340), Expect = 1e-31
Identities = 84/249 (33%), Positives = 131/249 (52%), Gaps = 13/249 (5%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
VA+K + ++ E F + I+ PH+ R++G C P+ +V+E +LG+L A+
Sbjct: 510 VAIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVMPIWIVMELAKLGELRAY 569
Query: 782 LRAAIPPTA-ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE 840
L+ + TLL Q++ + YLES FVHRD+AARN L+ +K++DFG
Sbjct: 570 LKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRW 629
Query: 841 AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTD 900
YY V LP++W + ES+ ++TT SDVW F V + EI L +P++ + +
Sbjct: 630 VSDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILML-GVKPFQGVKN 688
Query: 901 CEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI----HLFLQ 956
+V+ L+ ++G E + P CP LY LM +CW + L RP F I H L
Sbjct: 689 SDVI-----LKLENG--ERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEILI 741
Query: 957 RKSLNYATT 965
S+N + T
Sbjct: 742 EDSINSSET 750
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 140 bits (340), Expect = 1e-31
Identities = 79/245 (32%), Positives = 125/245 (51%), Gaps = 12/245 (4%)
Query: 711 YNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVV 769
+ G + + VAVK C ++++F ++ IL P++ ++G C PL ++
Sbjct: 635 FKGYLKTHNMEVAVKS-CRSEDFPDKQKFLQEAEILKQYRHPNIVELIGVCAEKEPLYII 693
Query: 770 LEYLELGDLCAFLRAAIPPTAAT--LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKG 827
+E + G+ +FLR L + + AAGM +LE N +HRDLAARNCL+G
Sbjct: 694 MELMAGGNFLSFLRGPEGKRLKVNNLTEMCVEAAAGMVFLEQRNCIHRDLAARNCLVGDN 753
Query: 828 YQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIY 887
+KISDFG E Y G +P++W + E++ G+YTT+SDVW++ + L E Y
Sbjct: 754 NVLKISDFGMSREEDDGIYTVSSGLKQIPIKWTSPEALNYGRYTTQSDVWSYGILLWETY 813
Query: 888 SLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPT 947
+ PY + + E + + + R CP +Y+LML CW D RP+
Sbjct: 814 TY-GSGPYPGMNNRETRERIESNYR-------MPRPELCPHPVYKLMLSCWEYDPDKRPS 865
Query: 948 FGEIH 952
F EI+
Sbjct: 866 FAEIY 870
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 140 bits (340), Expect = 1e-31
Identities = 99/282 (35%), Positives = 142/282 (50%), Gaps = 28/282 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R + M +KL G +G VY G +AVK L DA EF
Sbjct: 305 ELDRSEIIMHNKLGGGQYGDVY----------EGYWKRHDCTIAVKALKEDAM--PLHEF 352
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLR----AAIPPTAATLL 794
+ I+ L +L R+LG C P ++ E++ G+L +LR + +PP L+
Sbjct: 353 LAEAAIMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPII--LV 410
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
+A+QIA+GM YLE+ +F+HRDLAARNCL+ + +KI+DFG D Y
Sbjct: 411 QMASQIASGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKE-DTYTAHAGAK 469
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
P++W A E + +++KSDVWAF V L EI + PY + L N+ L ++
Sbjct: 470 FPIKWTAPEGLAFNTFSSKSDVWAFGVLLWEI-ATYGMAPYPGVE----LSNVYGL-LEN 523
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
G +D GCP +Y LML+CW DRP F +IH L+
Sbjct: 524 GF--RMDGPQGCPPSVYRLMLQCWNWSPSDRPRFRDIHFNLE 563
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 140 bits (339), Expect = 2e-31
Identities = 98/299 (32%), Positives = 150/299 (50%), Gaps = 31/299 (10%)
Query: 660 PSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEK 719
P Q+ ++ ++ + +V E PR +++ KL G FG V+ +G +NG +
Sbjct: 281 PRQKPVMFEISK-----DVWEIPRRSIKLERKLGNGQFGEVW----EGT--WNGTVR--- 326
Query: 720 RLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDL 778
VAVK L A + F ++ I+ L P L +L C P+ +V E + G L
Sbjct: 327 --VAVKTLKEGAM--DPTAFLQEANIMKKLRHPKLVALLAVCSEGEPIYIVTELMTNGCL 382
Query: 779 CAFLRAAIPPTAAT--LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG 836
+L L+ I Q+A GM YLES FVHRDLAARN L+G K++DFG
Sbjct: 383 LDYLHEGEGKQLREPELIDITAQVADGMAYLESQRFVHRDLAARNILVGDLRNCKVADFG 442
Query: 837 TDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ +Y +G +P++W A E++ GK+T KSDVW+F + ++E+ + R PY
Sbjct: 443 L-SRIIEDEYIAKEG-AKMPIKWTAPEAINFGKFTIKSDVWSFGILIYEVITK-GRVPYP 499
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+ + EVLD +S + + P CP LY++ +CW RPTF +H FL
Sbjct: 500 GMVNREVLDQVSRGYR-------MPKPPECPDQLYDITKQCWDAVPEKRPTFEFLHSFL 551
>UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor
precursor; n=1; Hydra vulgaris|Rep: Fibroblast growth
factor receptor precursor - Hydra attenuata (Hydra)
(Hydra vulgaris)
Length = 816
Score = 140 bits (339), Expect = 2e-31
Identities = 96/289 (33%), Positives = 149/289 (51%), Gaps = 30/289 (10%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EGAFG V+ A A +P + G T VAVK L D ++ ++F ++ ++ ++
Sbjct: 480 LGEGAFGRVFRATARDLPNHTGVQT-----VAVKMLKEDCCEQDLKDFISEIEVMKSIGK 534
Query: 752 P-HLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-----------LLHIAT 798
++ +L + + L +V+EY G+L +FL+ P A L
Sbjct: 535 HINILNLLAVSSQQGKLYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKITLYDLTSFCL 594
Query: 799 QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYK--VDGRVPLP 856
Q+A GM +L S +HRD+AARN L+G+GY +KI+DFG + + DYY+ DGR LP
Sbjct: 595 QVARGMNFLASKKCIHRDIAARNVLVGEGYLMKIADFGLARDIHEQDYYRKCTDGR--LP 652
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A E++ YTT+SD+W+F + EI + PY + L+ L L
Sbjct: 653 VKWMAIEALFDRVYTTQSDIWSFGILAWEIVTF-GGSPYPGI----ALEKLFDLLKQGYR 707
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNYATT 965
E R C D+Y LML CW+ RPTF ++ L+R L+ ++T
Sbjct: 708 ME---RPLNCTDDMYTLMLNCWKEIPSKRPTFSQLIEDLERMLLDASST 753
>UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2
precursor; n=36; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-2 precursor - Homo sapiens
(Human)
Length = 1255
Score = 140 bits (339), Expect = 2e-31
Identities = 91/269 (33%), Positives = 146/269 (54%), Gaps = 19/269 (7%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
LR + L GAFGTVY + +P+ K VA+K L + + K +E + +
Sbjct: 720 LRKVKVLGSGAFGTVY--KGIWIPDGENV----KIPVAIKVLRENTSPKANKEILDEAYV 773
Query: 746 LAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGM 804
+A + SP+++R+LG C + + +V + + G L +R + LL+ QIA GM
Sbjct: 774 MAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGM 833
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN--EAYTCDYYKVDGRVPLPLRWAAW 862
YLE + VHRDLAARN L+ +KI+DFG + +Y+ G+V P++W A
Sbjct: 834 SYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKV--PIKWMAL 891
Query: 863 ESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDR 922
ES+LR ++T +SDVW++ VT+ E+ + +PY+ + E+ D L + G E + +
Sbjct: 892 ESILRRRFTHQSDVWSYGVTVWELMTF-GAKPYDGIPAREIPDLL-----EKG--ERLPQ 943
Query: 923 APGCPRDLYELMLECWRRDELDRPTFGEI 951
P C D+Y +M++CW D RP F E+
Sbjct: 944 PPICTIDVYMIMVKCWMIDSECRPRFREL 972
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 140 bits (338), Expect = 2e-31
Identities = 84/240 (35%), Positives = 132/240 (55%), Gaps = 12/240 (5%)
Query: 720 RLVAVKFLCHDATLKE-REEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDL 778
+ VAVK L ++A ++E + ++ L +P++ R++G C + +V+E ELG L
Sbjct: 397 KTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPL 456
Query: 779 CAFLRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
+L+ ++ + Q++ GM+YLE NFVHRDLAARN L+ + KISDFG
Sbjct: 457 NKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGL- 515
Query: 839 NEAYTCD--YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
++A D YYK P++W A E + K+++KSDVW+F V + E +S ++PY
Sbjct: 516 SKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSY-GQKPYR 574
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ EV L + G E + GCPR++Y+LM CW D +RP F + L L+
Sbjct: 575 GMKGSEVTAML-----EKG--ERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLR 627
>UniRef50_Q26614 Cluster: Fibroblast growth factor receptor
precursor; n=4; Eumetazoa|Rep: Fibroblast growth factor
receptor precursor - Strongylocentrotus purpuratus
(Purple sea urchin)
Length = 972
Score = 140 bits (338), Expect = 2e-31
Identities = 96/292 (32%), Positives = 157/292 (53%), Gaps = 36/292 (12%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEK-RLVAVKFLCHDATLKEREE 738
EFPR RL + + EGAFG V + EA G+ + EK VAVK L +A +E +
Sbjct: 633 EFPRDRLTVGKTIGEGAFGKVVIGEAVGI------VCQEKTSTVAVKMLKANAMDREFSD 686
Query: 739 FERDVRILAAL-SSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP-------- 788
++ ++ + +P++ +LG C + P V++E+ G+L FLR+ PP
Sbjct: 687 LISELAMMKMIGKNPNIINLLGCCTQEGPPYVIVEFAHHGNLRDFLRSRRPPEEYEKSIL 746
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
T L+ +A Q+A GM +L S +HRDLAARN L+ + +++KI DFG +
Sbjct: 747 LTTSQTLTNKDLMSMAYQVARGMDFLASKKCIHRDLAARNVLVTEDFEMKICDFGLARDI 806
Query: 842 YTCDYYK--VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLT 899
+ D+Y+ DGR LP++W A E++ +TT+SDVW+F + L EI +L PY +
Sbjct: 807 HYIDFYRKTTDGR--LPVKWMAPEALFDRMFTTQSDVWSFGILLWEIMTL-GGTPYPSVP 863
Query: 900 DCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ D +L++ + +++ ++Y ++ ECWR RPTF E+
Sbjct: 864 VEQMFD---YLRSG----KRLEKPQNTSLEIYHILCECWRTSPGQRPTFCEL 908
>UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1
precursor; n=33; Euteleostomi|Rep: Fibroblast growth
factor receptor 1 precursor - Xenopus laevis (African
clawed frog)
Length = 812
Score = 140 bits (338), Expect = 2e-31
Identities = 97/290 (33%), Positives = 148/290 (51%), Gaps = 29/290 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E R RL + L EG FG V +AEA G+ + ++ VAVK L DA+ K+ +
Sbjct: 466 EVARDRLILGKPLGEGCFGQVVMAEAIGLDKEK---PNKVTKVAVKMLKSDASEKDLSDL 522
Query: 740 ERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP--------- 788
++ ++ + ++ +LGAC + PL V++EY G+L +LRA PP
Sbjct: 523 ISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYTSKGNLREYLRARRPPAMEYCYNPT 582
Query: 789 -------TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
+ L+ A Q+A GM YL S +HRDLAARN L+ + +KI+DFG +
Sbjct: 583 CVPDQLLSFKDLVSCAYQVARGMDYLASKKCIHRDLAARNVLVTEDNIMKIADFGLARDI 642
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
+ DYYK LP++W A E++ YT +SDVW+F V L EI++L PY +
Sbjct: 643 HHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL-GGSPYPGVP-- 699
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ L L + +D+ C +LY +M +CW RPTF ++
Sbjct: 700 --MEELFKLLKEG---HRMDKPTNCTNELYMMMKDCWHAMPSQRPTFNQL 744
>UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA;
n=3; Tribolium castaneum|Rep: PREDICTED: similar to
CG14992-PA - Tribolium castaneum
Length = 1000
Score = 139 bits (337), Expect = 3e-31
Identities = 93/280 (33%), Positives = 139/280 (49%), Gaps = 18/280 (6%)
Query: 682 PRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER--EEF 739
P + + KL +G+FG V E NG + VAVK L DA + E+F
Sbjct: 107 PESNITLSIKLGDGSFGVVRRGEWTSP---NGRVLP----VAVKILKADALSQPGVFEDF 159
Query: 740 ERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLL-HIAT 798
++V+ + LS P+L R+ G S P+ +V E LG L +LR T +L AT
Sbjct: 160 IKEVQAMHVLSHPNLIRLYGVVLSQPMMMVTELANLGSLLDYLRKQCQQTPVPMLCEYAT 219
Query: 799 QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPL 857
Q+A GM YLES F+HRDLA RN L+ +IKI DFG D Y + +P
Sbjct: 220 QVATGMAYLESKRFLHRDLACRNVLLASADKIKIGDFGLMRALPQEEDCYVMTEHKKVPF 279
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
W A ES+ +++ SD W F VT+ E+++ P+ L E+L + D
Sbjct: 280 PWCAPESLRSRQFSHASDTWMFGVTVWEMFTF-GEDPWMGLIGSEILRKI------DKEG 332
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
E + + CP +Y ++L+CW ++ +RPTF + F ++
Sbjct: 333 ERLHQPEACPPAVYSILLQCWLKNPTERPTFAALKEFFRK 372
>UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4
precursor; n=58; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-4 precursor - Homo sapiens
(Human)
Length = 1308
Score = 139 bits (337), Expect = 3e-31
Identities = 94/268 (35%), Positives = 139/268 (51%), Gaps = 17/268 (6%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
L+ + L GAFGTVY + VPE + K VA+K L K EF + I
Sbjct: 718 LKRVKVLGSGAFGTVY--KGIWVPEGE----TVKIPVAIKILNETTGPKANVEFMDEALI 771
Query: 746 LAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLL-HIATQIAAGM 804
+A++ PHL R+LG C SP + +V + + G L ++ + LL + QIA GM
Sbjct: 772 MASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGM 831
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD-YYKVDGRVPLPLRWAAWE 863
YLE VHRDLAARN L+ +KI+DFG + Y DG +P++W A E
Sbjct: 832 MYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGG-KMPIKWMALE 890
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
+ K+T +SDVW++ VT+ E+ + +PY+ + E+ D L + G E + +
Sbjct: 891 CIHYRKFTHQSDVWSYGVTIWELMTF-GGKPYDGIPTREIPDLL-----EKG--ERLPQP 942
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
P C D+Y +M++CW D RP F E+
Sbjct: 943 PICTIDVYMVMVKCWMIDADSRPKFKEL 970
>UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n=2;
Danio rerio|Rep: UPI00015A61DF UniRef100 entry - Danio
rerio
Length = 985
Score = 139 bits (336), Expect = 4e-31
Identities = 91/261 (34%), Positives = 138/261 (52%), Gaps = 18/261 (6%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EG FG V+ DG+ Y + E+ VAVK C D + +E+F + I+ L
Sbjct: 368 LGEGFFGEVH----DGI--YKSK-SGERVNVAVK-TCKDCSADVKEKFMSEALIMKKLDH 419
Query: 752 PHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQYLESL 810
PH+ R++G P+ +V+E G+L +L+ T TL+ + QI+ + YLE +
Sbjct: 420 PHIVRLIGIIEEDPVWIVMELYPFGELENYLKDNQNKLTNVTLILYSLQISKALAYLEGV 479
Query: 811 NFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKY 870
N VHRD+A RN L+ K +K+ DFG +YYK LP++W A ES+ ++
Sbjct: 480 NMVHRDIAVRNVLVAKVDCVKLGDFGLSRYIEEEEYYKA-SVTRLPIKWMAPESINFRRF 538
Query: 871 TTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDL 930
T+ SDVW FAV + EI S ++P+ L + +V++ Q + GM + + CP L
Sbjct: 539 TSASDVWMFAVCMWEIMS-GGQQPFFWLENKDVIN-----QLEQGM--RLPKPERCPPTL 590
Query: 931 YELMLECWRRDELDRPTFGEI 951
Y LM CW DRP+F E+
Sbjct: 591 YSLMTRCWSYSPRDRPSFTEL 611
>UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor
precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CD136
antigen) (CDw136) [Contains: Macrophage- stimulating
protein receptor alpha chain; Macrophage-stimulating
protein receptor beta chain]; n=15; Eutheria|Rep:
Macrophage-stimulating protein receptor precursor (EC
2.7.10.1) (MSP receptor) (p185-Ron) (CD136 antigen)
(CDw136) [Contains: Macrophage- stimulating protein
receptor alpha chain; Macrophage-stimulating protein
receptor beta chain] - Homo sapiens (Human)
Length = 1400
Score = 139 bits (336), Expect = 4e-31
Identities = 87/262 (33%), Positives = 135/262 (51%), Gaps = 20/262 (7%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
+ +G FG VY E + + I A+K L +++ E F R+ ++ L+
Sbjct: 1088 IGKGHFGVVYHGEY--IDQAQNRIQC-----AIKSLSRITEMQQVEAFLREGLLMRGLNH 1140
Query: 752 PHLARVLGACRSPPLA--VVLEYLELGDLCAFLRAAIP-PTAATLLHIATQIAAGMQYLE 808
P++ ++G P V+L Y+ GDL F+R+ PT L+ Q+A GM+YL
Sbjct: 1141 PNVLALIGIMLPPEGLPHVLLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLA 1200
Query: 809 SLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVD--GRVPLPLRWAAWESVL 866
FVHRDLAARNC++ + + +K++DFG + +YY V LP++W A ES+
Sbjct: 1201 EQKFVHRDLAARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQ 1260
Query: 867 RGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGC 926
++TTKSDVW+F V L E+ + PY H+ + L+H A + + C
Sbjct: 1261 TYRFTTKSDVWSFGVLLWELLTR-GAPPYRHIDPFD----LTHFLAQG---RRLPQPEYC 1312
Query: 927 PRDLYELMLECWRRDELDRPTF 948
P LY++M +CW D RPTF
Sbjct: 1313 PDSLYQVMQQCWEADPAVRPTF 1334
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 138 bits (335), Expect = 5e-31
Identities = 92/274 (33%), Positives = 143/274 (52%), Gaps = 21/274 (7%)
Query: 682 PRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFER 741
P RL+M + EG FG+VY + NG E+ VA+K + H+ ++ +
Sbjct: 446 PLERLKMGRVIGEGEFGSVYEGT---YTKRNG----EEIKVAIKTVRHEQ-IETSNAILK 497
Query: 742 DVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFL---RAAIPPTAATLLHIAT 798
+ ++ L+ + +++G + PL +V E + LG + ++ + +I P + + A
Sbjct: 498 EAHVMMRLNHHCVVKLIGLSKGRPLLMVQELVALGSMLNYIILNKESINPNSEFKIW-AA 556
Query: 799 QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPL 857
QIA GM YLE F+HRDLAARN L+ +Q KISDFG A +YY+ PL
Sbjct: 557 QIACGMNYLEEQRFIHRDLAARNILLASQHQAKISDFGLSRALAADHEYYRALQGGKWPL 616
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
+W A ES G+++ KSDVW+F V + E+YS PY L + + + +DG
Sbjct: 617 KWYAPESYNYGQFSHKSDVWSFGVAIWEMYSF-GDVPYGELKGSDAIKII-----EDG-- 668
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E + + CP +YE+M CW D +RPTF E+
Sbjct: 669 ERLKQPDACPDHIYEIMRRCWEYDAENRPTFKEL 702
>UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG10023-PA, isoform A - Tribolium castaneum
Length = 1106
Score = 138 bits (335), Expect = 5e-31
Identities = 89/277 (32%), Positives = 140/277 (50%), Gaps = 16/277 (5%)
Query: 676 TNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE 735
T E R ++++ L EG FG V+ +G++ VAVK +A L
Sbjct: 418 TKSYELQRDQIQLGEILGEGQFGDVHKGTYKAK---DGSLIP----VAVKTCKREADLNT 470
Query: 736 REEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPT-AATLL 794
E+F + I+ H+ +++G C P+ +V+E +LG+L A+L+ ATLL
Sbjct: 471 TEKFLEEAYIMQKFDHQHIIKLIGVCSESPVWIVMELAKLGELRAYLQNNKDDLDLATLL 530
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
A Q++ + YLES FVHRD+AARN L+ +K+ DFG Y +
Sbjct: 531 LYAFQLSTALSYLESKKFVHRDIAARNVLVSSHTSVKLGDFGLSRSMNDDQSYYKASKGK 590
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
LP++W + ES+ ++T SDVW F V + EI + +P++ + + EVL + ++
Sbjct: 591 LPIKWMSPESINFRRFTIASDVWMFGVCMWEIL-MYGIKPFQGVKNNEVLTKI-----EN 644
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
G E + P CP LY LM +CW + RP+F EI
Sbjct: 645 G--ERLALPPNCPPRLYSLMSQCWSYEPSKRPSFKEI 679
>UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6;
Eumetazoa|Rep: Tyrosine kinase receptor ron - Canis
familiaris (Dog)
Length = 998
Score = 138 bits (335), Expect = 5e-31
Identities = 88/262 (33%), Positives = 133/262 (50%), Gaps = 20/262 (7%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
+ +G FG VY E + E I AVK L ++E E F R+ ++ L
Sbjct: 686 IGKGHFGVVYHGEY--IDEDQNRIHC-----AVKSLSRITEVQEAEAFLREGLLMRGLHH 738
Query: 752 PHLARVLGACRSPP--LAVVLEYLELGDLCAFLRAAIP-PTAATLLHIATQIAAGMQYLE 808
P++ ++G P V+L Y+ GDL F+R+ PT L+ Q+A GM+YL
Sbjct: 739 PNVLALIGIVLPPEGLPRVLLPYMRHGDLLRFIRSPQRNPTVKDLISFGLQVARGMEYLA 798
Query: 809 SLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV--DGRVPLPLRWAAWESVL 866
FVHRDLAARNC++ + + +K++DFG + +YY V LP++W A ES+
Sbjct: 799 EQKFVHRDLAARNCMLDESFTVKVADFGLARDILDKEYYSVRQHRHARLPVKWMALESLQ 858
Query: 867 RGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGC 926
++TTKSDVW+F V L E+ + PY H+ +++ L+ + + + C
Sbjct: 859 TYRFTTKSDVWSFGVLLWELLTR-GAPPYPHIDPFDLIQFLAQGRR-------LPQPEYC 910
Query: 927 PRDLYELMLECWRRDELDRPTF 948
P LY +M CW D RPTF
Sbjct: 911 PNSLYMVMQRCWAVDPAVRPTF 932
>UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF5507, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1116
Score = 138 bits (334), Expect = 7e-31
Identities = 88/234 (37%), Positives = 130/234 (55%), Gaps = 17/234 (7%)
Query: 666 LLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVK 725
LL L+R L E PR R++ KL EG FG V+ A ++E R VA+K
Sbjct: 352 LLCLQRELFDMEPWERPREEFRLLRKLGEGHFGEVWEA----------LWSTENRRVAIK 401
Query: 726 FLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA 784
L + T +++EF ++V+ L +L P L ++L C R P+ +V E + G L A+L +
Sbjct: 402 TLKQEDT--KQDEFVKEVQALKSLHHPKLIQLLAMCSRGEPVYIVTELMTKGSLKAYLAS 459
Query: 785 AIPP--TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAY 842
A T+A L+++ +QIA GM YLE N VHRDLAARN L+G+ K++DFG
Sbjct: 460 AEGQVLTSAHLIYMGSQIAEGMAYLEDRNIVHRDLAARNILVGEDLVCKVADFGL-ARII 518
Query: 843 TCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
Y +P+RW A E+ + +++ KSDVW+F V L+E+ S + PYE
Sbjct: 519 KDSVYTASRNTKIPVRWTAPEAAIHQRFSVKSDVWSFGVLLYEMMSR-GKMPYE 571
Score = 118 bits (283), Expect = 1e-24
Identities = 66/168 (39%), Positives = 94/168 (55%), Gaps = 6/168 (3%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VAVK L D+ L + F+ +V+IL L HL + C S P ++ E +E G L
Sbjct: 856 VAVKILKSDSELNHGD-FQTEVQILKNLRHRHLLSLFAVCTESRPYWIITELMEKGSLLI 914
Query: 781 FLRAAIPPT--AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
FLR+ A+L+ + TQ+A GM YLE +HRDLAARN L+G+ Y K+ DFG
Sbjct: 915 FLRSPEGQNQDVASLIDMGTQVADGMSYLEEQKSIHRDLAARNVLVGEDYTCKVGDFGLA 974
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEI 886
Y D ++ P +W A E++ GK++ KSDVW+F + L+EI
Sbjct: 975 RVIKEPFYITEDKKI--PYKWTAPEAISHGKFSNKSDVWSFGILLYEI 1020
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 138 bits (334), Expect = 7e-31
Identities = 80/231 (34%), Positives = 123/231 (53%), Gaps = 13/231 (5%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
+A+K L + R +F R+ ++ L + +++G C+ PPL +V E + LG + +
Sbjct: 688 IAIKQLVESTGKRNRVDFLREASVMIRLRHHCIVKLIGICKGPPLMMVEELVPLGSMLDY 747
Query: 782 L---RAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
+ + I P ++ A QIA GMQYLE +FVHRDLAARN L+ Q KISDFG
Sbjct: 748 IIANKGTINPKLELVIW-AAQIACGMQYLEQHHFVHRDLAARNILLASRNQAKISDFGLS 806
Query: 839 NE-AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
DYY+ P++W A ES G ++ SDVW+F VT+ E+YSL PY+
Sbjct: 807 RAIGAGDDYYRASQGGKWPIKWYAPESFNYGTFSHASDVWSFGVTMWEMYSL-GAPPYQD 865
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ +V+ + + Q + + CP +++E+M CW + RPTF
Sbjct: 866 MKGVDVIKLIENGQR-------LSQPDLCPENVFEVMKNCWNYNPKSRPTF 909
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 138 bits (334), Expect = 7e-31
Identities = 93/280 (33%), Positives = 139/280 (49%), Gaps = 26/280 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR LR+ KL +G FG V++ +G + VA+K L + E F
Sbjct: 271 EIPRESLRLEVKLGQGCFGEVWMGTWNGTTK-----------VAIKTLKPGTMMPEA--F 317
Query: 740 ERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP--TAATLLHIA 797
++ +I+ L L + P+ +V E++ G L FL+ L+ +A
Sbjct: 318 LQEAQIMKKLRHDKLVPLYAVVSEEPIYIVTEFMSKGSLLDFLKEGDGKYLKLPQLVDMA 377
Query: 798 TQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPL 857
QIA GM Y+E +N++HRDL A N L+G+ KI+DFG +Y G P+
Sbjct: 378 AQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQG-AKFPI 436
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDG-M 916
+W A E+ L G++T KSDVW+F + E+ + R PY + + EVL+ Q + G
Sbjct: 437 KWTAPEAALYGRFTIKSDVWSFGILQTELVTK-GRVPYPGMVNREVLE-----QVERGYR 490
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
C GCP L+ELM CW++D +RPTF I FL+
Sbjct: 491 MPC---PQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 138 bits (334), Expect = 7e-31
Identities = 82/267 (30%), Positives = 143/267 (53%), Gaps = 26/267 (9%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
L ++ +L G FG V + + G+I + AVK + + T+ E ++F + ++
Sbjct: 526 LMLMEELGSGQFGVVRRGK------WRGSIDT-----AVKMM-KEGTMSE-DDFIEEAKV 572
Query: 746 LAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA---AIPPTAATLLHIATQIA 801
+ L P+L ++ G C + P+ +V EY++ G L +LR + LL + Q++
Sbjct: 573 MTKLQHPNLVQLYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVS 632
Query: 802 AGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAA 861
GM YLE N++HRDLAARNCL+G +K++DFG D Y G P++WA
Sbjct: 633 KGMTYLERHNYIHRDLAARNCLVGSENVVKVADFGLARYVLD-DQYTSSGGTKFPIKWAP 691
Query: 862 WESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVD 921
E + ++++KSDVWA+ V + EI++ C + PY L + EV++ + G+ ++
Sbjct: 692 PEVLNYTRFSSKSDVWAYGVLMWEIFT-CGKMPYGRLKNTEVVERVQR-----GII--LE 743
Query: 922 RAPGCPRDLYELMLECWRRDELDRPTF 948
+ C +++Y++M CW +RP F
Sbjct: 744 KPKSCAKEIYDVMKLCWSHGPEERPAF 770
>UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family
protein tyrosine kinase; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to src-family protein
tyrosine kinase - Strongylocentrotus purpuratus
Length = 387
Score = 138 bits (333), Expect = 9e-31
Identities = 99/287 (34%), Positives = 144/287 (50%), Gaps = 26/287 (9%)
Query: 680 EFPRHRL-RMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
E PR L +M +L EG FG V+ GV +NG VAVK L + T+
Sbjct: 119 ETPRKSLGQMNRRLGEGKFGEVW----QGV--WNGNTP-----VAVKTL-KERTMSPAA- 165
Query: 739 FERDVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDLCAFLRA--AIPPTAATLLH 795
F + ++ L + ++ C P+ +V E + GDL +L++ TL+
Sbjct: 166 FLAEANVMKKLRHEGIVQLYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLID 225
Query: 796 IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPL 855
+ IA+GM YL S N VHRDLAARN L+GKG +KI+DFG + D Y + L
Sbjct: 226 MGAHIASGMDYLGSKNVVHRDLAARNVLVGKGNVVKIADFGR-AQLMEKDVYVGEEGAKL 284
Query: 856 PLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDG 915
PL+W A E+VL G++T KSDVW+F + + E+ + PY+ + EV +++
Sbjct: 285 PLKWTAPEAVLHGRFTIKSDVWSFGILMTEMVTF-GGYPYKKMRTREVTKKVANGYRMPK 343
Query: 916 MFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLNY 962
M C D LY +ML+CW +D RPTF +H + NY
Sbjct: 344 MDHCTD-------SLYMIMLKCWHKDPQQRPTFKYLHDYFVSTKPNY 383
>UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Tribolium castaneum
Length = 1293
Score = 138 bits (333), Expect = 9e-31
Identities = 94/289 (32%), Positives = 148/289 (51%), Gaps = 28/289 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR+ + + KL EGAFGTVY EA+ P+ G + VAVK L ++ +E+ +F
Sbjct: 895 EIPRNSVVINRKLGEGAFGTVYGGEAN-FPD-KGWVA-----VAVKTLKVGSSTEEKLDF 947
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA------------AI 786
+ ++ ++ ++LG C + P+ ++E++ GDL FL A +
Sbjct: 948 LSEAEVMKRFDHKNIIKLLGVCTKEEPIYTIMEFMLYGDLKTFLLARRHLVNDKTIEESD 1007
Query: 787 PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDY 846
++ L +A +A G+ YL L +VHRD+A+RNCLI +K++DFG + DY
Sbjct: 1008 EISSKKLTMMALDVARGLSYLAQLKYVHRDVASRNCLINAQRIVKLADFGMTRPMFENDY 1067
Query: 847 YKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDN 906
YK + LP+RW + ES+ G +T SDVW++ V L+EI + PY+ +T+ EVL+
Sbjct: 1068 YKFTRKGMLPVRWMSPESLALGVFTPSSDVWSYGVLLYEIITF-GSFPYQGMTNGEVLEY 1126
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+ + V G L L+ CW +D R EI FL
Sbjct: 1127 VKN-------GHTVTIPQGVKTQLRGLLKSCWHQDPKMRTRASEIVEFL 1168
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 138 bits (333), Expect = 9e-31
Identities = 91/288 (31%), Positives = 141/288 (48%), Gaps = 26/288 (9%)
Query: 673 LETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDAT 732
++T + E + + +I KL G FG V+ +G E VAVK L
Sbjct: 291 VKTKDHWEISKSSIVLIEKLGAGQFGEVWKGTWNGTTE-----------VAVKTLKQGTM 339
Query: 733 LKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT 792
KE +F ++ RI+ A P L R+ C P+ +V E + G L +LR
Sbjct: 340 TKE--DFLKEARIMRAAQHPKLVRLYAVCTEDPIYIVTELMCNGSLLQYLRDGPGKNLLI 397
Query: 793 --LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN--EAYTCDYYK 848
L+ + QIA GM YLE +++HRDLAARN L+G+ +K++DFG E + C Y
Sbjct: 398 NQLVDMMAQIANGMAYLEKEHYIHRDLAARNILVGENNCVKVADFGLARMVEDHYCT-YM 456
Query: 849 VDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLS 908
P++W A E+ L G++T KSDVW+F + ++E+ +L + PY + + E L
Sbjct: 457 AQKSTKFPIKWTAPEAALMGRFTIKSDVWSFGIVIYELITL-GQVPYPSMNNTETLH--- 512
Query: 909 HLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
Q G + R CP+ +Y+++L W RPTF + F +
Sbjct: 513 --QVSTGY--RMPRPVNCPQPIYDMLLRIWDSCPEKRPTFSSLFEFFE 556
>UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor receptor
2; n=11; Clupeocephala|Rep: Plasminogen related growth
factor receptor 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 1375
Score = 137 bits (332), Expect = 1e-30
Identities = 94/286 (32%), Positives = 146/286 (51%), Gaps = 25/286 (8%)
Query: 674 ETTNVIEFPRHRLRMISK--LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDA 731
E NV+ P LR+ + + +G FGTVY Y ++ AVK L
Sbjct: 1052 EVKNVL-IPADMLRIEDRQVIGKGHFGTVYHG-------YLIDSNKQETHCAVKSLNRIT 1103
Query: 732 TLKEREEFERDVRILAALSSPHLARVLGAC---RSPPLAVVLEYLELGDLCAFLRAAIP- 787
LK+ + F R+ I+ P++ +LG PL VVL Y++ GD+ F+R+
Sbjct: 1104 DLKDVDHFLREGLIMKGFDHPNILSLLGIMLPKEGLPL-VVLPYMKHGDVRHFIRSEKRN 1162
Query: 788 PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYY 847
PT L+ Q+A GM+YL FVHRDLAARNC++ + Y +K++DFG + Y +YY
Sbjct: 1163 PTVKDLIGFGLQVAKGMEYLAQKKFVHRDLAARNCMLDETYTVKVADFGMARDIYDKEYY 1222
Query: 848 KVDG--RVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
+ +V LP++W A ES+ K+T+KSDVW++ + + E+ + PY D + D
Sbjct: 1223 SIQDHKQVKLPVKWMAIESLQTQKFTSKSDVWSYGILMWELLTR-GASPY---PDVDPYD 1278
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++L + + CP LY +ML CW + RP+F +
Sbjct: 1279 ITNYLLKG----RRLPQPQFCPNTLYSIMLSCWDPEPDFRPSFSSL 1320
>UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55;
Euteleostomi|Rep: Tyrosine-protein kinase ZAP-70 - Homo
sapiens (Human)
Length = 619
Score = 137 bits (332), Expect = 1e-30
Identities = 88/232 (37%), Positives = 127/232 (54%), Gaps = 16/232 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAF 781
VA+K L + EE R+ +I+ L +P++ R++G C++ L +V+E G L F
Sbjct: 366 VAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKF 425
Query: 782 L---RAAIPPT-AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
L R IP + A LLH Q++ GM+YLE NFVHRDLAARN L+ + KISDFG
Sbjct: 426 LVGKREEIPVSNVAELLH---QVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGL 482
Query: 838 DNEAYTCD-YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
D YY PL+W A E + K++++SDVW++ VT+ E S ++PY+
Sbjct: 483 SKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSY-GQKPYK 541
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+ EV ++ ++ M EC P CP +LY LM +CW DRP F
Sbjct: 542 KMKGPEV---MAFIEQGKRM-EC---PPECPPELYALMSDCWIYKWEDRPDF 586
>UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO
precursor; n=37; Euteleostomi|Rep: Tyrosine-protein
kinase receptor UFO precursor - Homo sapiens (Human)
Length = 887
Score = 137 bits (332), Expect = 1e-30
Identities = 102/335 (30%), Positives = 162/335 (48%), Gaps = 33/335 (9%)
Query: 631 VGEPMDTLPDLGTRRSLNPSVRSKQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMIS 690
V EP +L R + S + + + + I +LK +L V RH++ +
Sbjct: 477 VFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMV---DRHKVALGK 533
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFL-CHDATLKEREEFERDVRILAAL 749
L EG FG V +G + +I VAVK + T E E+F + +
Sbjct: 534 TLGEGEFGAVM----EGQLNQDDSILK----VAVKTMKIAICTRSELEDFLSEAVCMKEF 585
Query: 750 SSPHLARVLGACRS-------PPLAVVLEYLELGDLCAFL---RAAIPPT---AATLLHI 796
P++ R++G C P V+L +++ GDL +FL R P L+
Sbjct: 586 DHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLVKF 645
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
IA+GM+YL + F+HRDLAARNC++ + + ++DFG + Y DYY+ +P
Sbjct: 646 MADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMP 705
Query: 857 LRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGM 916
++W A ES+ YT+KSDVW+F VT+ EI + + PY + + E+ D +L+ + +
Sbjct: 706 VKWIAIESLADRVYTSKSDVWSFGVTMWEI-ATRGQTPYPGVENSEIYD---YLRQGNRL 761
Query: 917 FECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ D C LY LM CW + DRP+F E+
Sbjct: 762 KQPAD----CLDGLYALMSRCWELNPQDRPSFTEL 792
>UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming
protein SEA; n=6; root|Rep: Tyrosine-protein kinase
transforming protein SEA - Avian erythroblastosis virus
(strain S13)
Length = 370
Score = 137 bits (332), Expect = 1e-30
Identities = 96/280 (34%), Positives = 139/280 (49%), Gaps = 25/280 (8%)
Query: 684 HRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDV 743
HR R+I + G FG+VY Y + AVK L L+E EEF R+
Sbjct: 61 HRSRVIGR---GHFGSVYHGT------YMDPLLGNLHC-AVKSLHRITYLEEVEEFLREG 110
Query: 744 RILAALSSPHLARVLGAC---RSPPLAVVLEYLELGDLCAFLRAAI-PPTAATLLHIATQ 799
++ P + +LG C PL VVL Y+ GDL F+RA PT L+ Q
Sbjct: 111 ILMKGFHHPQVLSLLGVCLPRHGLPL-VVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQ 169
Query: 800 IAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKV--DGRVPLPL 857
+A GM+YL FVHRDLAARNC++ + +K++DFG + + +YY + LP+
Sbjct: 170 VALGMEYLAQKKFVHRDLAARNCMLDETLTVKVADFGLARDVFGKEYYSIRQHRHAKLPV 229
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
RW A ES+ K+TTKSDVW+F V + E+ + PY + ++ L +
Sbjct: 230 RWMALESLQTQKFTTKSDVWSFGVLMWELLTR-GASPYPEVDPYDMARYLLRGRR----- 283
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+ + CP LY +ML CW +RP+F + L+R
Sbjct: 284 --LPQPQPCPDTLYGVMLSCWAPTPEERPSFSGLVCELER 321
>UniRef50_P52333 Cluster: Tyrosine-protein kinase JAK3; n=17;
Eutheria|Rep: Tyrosine-protein kinase JAK3 - Homo sapiens
(Human)
Length = 1124
Score = 137 bits (332), Expect = 1e-30
Identities = 100/285 (35%), Positives = 147/285 (51%), Gaps = 24/285 (8%)
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
F L+ IS+L +G FG+V + D + + GA LVAVK L H ++R+ F+
Sbjct: 817 FEERHLKYISQLGKGNFGSVELCRYDPLGDNTGA------LVAVKQLQHSGPDQQRD-FQ 869
Query: 741 RDVRILAALSSPHLARVLGACRSP---PLAVVLEYLELGDLCAFL-RAAIPPTAATLLHI 796
R+++IL AL S + + G P L +V+EYL G L FL R A+ LL
Sbjct: 870 REIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDASRLLLY 929
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN-EAYTCDYYKVDGRVPL 855
++QI GM+YL S VHRDLAARN L+ +KI+DFG DYY V
Sbjct: 930 SSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLDKDYYVVREPGQS 989
Query: 856 PLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRR-----RPYEHLTDCE----VLDN 906
P+ W A ES+ ++ +SDVW+F V L+E+++ C + + + CE L
Sbjct: 990 PIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRMMGCERDVPALCR 1049
Query: 907 LSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
L L ++G + + P CP +++ELM CW DRP+F +
Sbjct: 1050 LLEL-LEEG--QRLPAPPACPAEVHELMKLCWAPSPQDRPSFSAL 1091
Score = 53.6 bits (123), Expect = 2e-05
Identities = 55/219 (25%), Positives = 92/219 (42%), Gaps = 23/219 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKE-REE 738
+ P L L G+F +Y V + E R V DA K E
Sbjct: 515 KIPADSLEWHENLGHGSFTKIYRGCRHEV------VDGEARKTEVLLKVMDAKHKNCMES 568
Query: 739 FERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFL--RAAIPPTAATLLHI 796
F +++ +S HL + G C + +V E++ LG + +L R + P A+ L +
Sbjct: 569 FLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGHLVP-ASWKLQV 627
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLI------GKGYQIKISDFGTDNEAYTCDYYKVD 850
Q+A + YLE H +++AR L+ G IK+SD G + + +
Sbjct: 628 VKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPAVLSLE--MLT 685
Query: 851 GRVPLPLRWAAWESVLRGK-YTTKSDVWAFAVTLHEIYS 888
R+P W A E + + + ++D W F T+ E++S
Sbjct: 686 DRIP----WVAPECLREAQTLSLEADKWGFGATVWEVFS 720
>UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1
precursor; n=2; Dugesia japonica|Rep: Fibroblast growth
factor receptor 1 precursor - Dugesia japonica
(Planarian)
Length = 854
Score = 137 bits (332), Expect = 1e-30
Identities = 102/289 (35%), Positives = 154/289 (53%), Gaps = 35/289 (12%)
Query: 680 EFPRHRLRMISK-LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
EFPR +L++ +K L EGAFG VY A+ + + I VAVK + D + +
Sbjct: 544 EFPREKLKITNKKLGEGAFGMVYEGIANDIGNRSNPIK-----VAVKMMRDDFSDSNVHD 598
Query: 739 FERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP-------- 788
F +++ I+ + P++ ++LG C + PL V++E G+L F+RA
Sbjct: 599 FVKEMEIMKHIGRHPNVIQLLGLCTQKGPLRVIVELAPYGNLRDFVRAKNKKYSKSKKII 658
Query: 789 ---TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD 845
T++ L + QIA GM YL S + VHRDL+ARN L+G+ +++KI+DFG D
Sbjct: 659 GNFTSSILCTYSLQIARGMTYLASRSVVHRDLSARNILVGEHFEMKIADFGLTR---IVD 715
Query: 846 YY---KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCE 902
YY K DG LP++W A E++L KYTTKSDVW++ + L EI++L PY + +
Sbjct: 716 YYYRKKTDG--ILPVKWMAPEALLEKKYTTKSDVWSYGILLWEIFTL-GDSPYSAILPEK 772
Query: 903 VLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
V+D L + E + ++Y LM CW +RP F EI
Sbjct: 773 VVD-LIRKGFQNPKPELAN------FEIYRLMQHCWSLSSENRPNFFEI 814
>UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24;
Euteleostomi|Rep: Activated CDC42 kinase 1 - Homo
sapiens (Human)
Length = 1036
Score = 137 bits (332), Expect = 1e-30
Identities = 95/274 (34%), Positives = 136/274 (49%), Gaps = 18/274 (6%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER--EEFERDV 743
LR++ KL +G+FG V E D +G S VAVK L D + ++F R+V
Sbjct: 126 LRLLEKLGDGSFGVVRRGEWDAP---SGKTVS----VAVKCLKPDVLSQPEAMDDFIREV 178
Query: 744 RILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAA 802
+ +L +L R+ G +PP+ +V E LG L LR TL A Q+A
Sbjct: 179 NAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAE 238
Query: 803 GMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWAA 861
GM YLES F+HRDLAARN L+ +KI DFG D+Y + +P W A
Sbjct: 239 GMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCA 298
Query: 862 WESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVD 921
ES+ ++ SD W F VTL E+++ + P+ L ++L + D E +
Sbjct: 299 PESLKTRTFSHASDTWMFGVTLWEMFTY-GQEPWIGLNGSQILHKI------DKEGERLP 351
Query: 922 RAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
R CP+D+Y +M++CW DRPTF + FL
Sbjct: 352 RPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
>UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n=3;
Danio rerio|Rep: UPI00015A7C25 UniRef100 entry - Danio
rerio
Length = 759
Score = 137 bits (331), Expect = 2e-30
Identities = 82/247 (33%), Positives = 134/247 (54%), Gaps = 17/247 (6%)
Query: 711 YNGAITSEKRLVAVKFLCHDATLKEREEFERDV-RILAALSSPHLARVLGAC-RSPPLAV 768
++G + S+ VAVK + + + +F + RIL P++ +++G C + P+ +
Sbjct: 506 FSGRLRSDNTPVAVKACRENLPAEHKNKFLMEAARILKQYDHPNIVKLIGVCTQKQPIYI 565
Query: 769 VLEYLELGDLCAFLRA-AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKG 827
++E ++ GD FLR ++ L+ +A +A+G+ YLES +HRD+AARNCL+G+
Sbjct: 566 IMELVQGGDFLTFLRTEGHNLKSSMLIRMAENVASGLAYLESKKCIHRDVAARNCLVGEE 625
Query: 828 YQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESV---LRGKYTTKSDVWAFAVTLH 884
+KISDFG E Y G +P++W A E++ G+YTT+SDVW+F V L
Sbjct: 626 SVVKISDFGMSREEQDGVYSATGGMKQIPVKWTAPEALNYGSPGRYTTESDVWSFGVLLW 685
Query: 885 EIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAP---GCPRDLYELMLECWRRD 941
E +S +T + +S+ Q D + E R P CP ++Y LM +CW+ D
Sbjct: 686 ETFS-------RGVTPYTIPTVMSNQQTRDEV-ERGYRMPAPNNCPDEIYTLMCQCWQYD 737
Query: 942 ELDRPTF 948
RP+F
Sbjct: 738 PRKRPSF 744
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 137 bits (331), Expect = 2e-30
Identities = 78/230 (33%), Positives = 128/230 (55%), Gaps = 14/230 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K + + + E ++F + +++ +L ++ G C ++ P+ +V E + G L
Sbjct: 458 VAIKMM-REGAMNE-DDFIEEAKVMKQFQHENLVKLYGVCTKNGPIFIVQELMVNGCLLQ 515
Query: 781 FLRAAIPPTAAT--LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
FLR T +L +ATQI + M+YLE F+HRDLAARNCL+G+ +K++DFG
Sbjct: 516 FLRQRKELVEKTEIILDMATQICSAMKYLEESGFIHRDLAARNCLVGERNVVKVADFGLA 575
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
+Y +G P++WAA E + K+++KSDVW+F + L E+++ + PY
Sbjct: 576 RFVVDDEYTASEG-TKFPIKWAAPEVITHAKFSSKSDVWSFGILLWELWT-GGKTPYPTF 633
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
T+ +VLD + M +DR CP ++Y LM +CW + DRP F
Sbjct: 634 TNSQVLDEVL-------MGYRLDRPKQCPPEVYALMGKCWLTNSDDRPQF 676
>UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to p80 protein, partial -
Strongylocentrotus purpuratus
Length = 526
Score = 136 bits (330), Expect = 2e-30
Identities = 83/211 (39%), Positives = 119/211 (56%), Gaps = 19/211 (9%)
Query: 752 PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIP----PTAAT---LLHIATQIAAG 803
P++ +LG C + PL +VLEY+E G+L FLR P P++ T LL I +A G
Sbjct: 7 PNVVSLLGICFKEKPLFIVLEYMEGGELKQFLRDIRPTEEKPSSITMKDLLQITQDVAQG 66
Query: 804 MQYLESLNFVHRDLAARNCLIG---KGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWA 860
+YLES F+HRD+AARN L+ G KI+DFG + Y DYY+ G+ LP++W
Sbjct: 67 CRYLESRRFIHRDIAARNILLTTKESGRAAKIADFGMARDIYRADYYRKGGQALLPVKWM 126
Query: 861 AWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECV 920
E+ G +T+K+DVWA+ V L EI SL PY +++ EV+ +S E +
Sbjct: 127 PPEAFQDGIFTSKTDVWAYGVLLWEIISL-GFMPYPGMSNQEVIQFVS-------AGERM 178
Query: 921 DRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ CP+ ++ LM +CWR DRP F I
Sbjct: 179 NPPRSCPQPVFNLMSQCWRHIPEDRPPFTTI 209
>UniRef50_UPI0000DB7B4C Cluster: PREDICTED: similar to hopscotch
CG1594-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to
hopscotch CG1594-PA - Apis mellifera
Length = 1133
Score = 136 bits (330), Expect = 2e-30
Identities = 92/270 (34%), Positives = 136/270 (50%), Gaps = 13/270 (4%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLK-EREEFERDVRILAAL 749
K+ +G +G VY G E E + VA+K L L+ + +FER++ I+ L
Sbjct: 857 KIGQGFYGEVY----RGTLERENGKDIEPQQVAIKKLKKKRALETDINDFEREITIMKTL 912
Query: 750 SSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQYLE 808
+ P++ ++LG P + +V+EY++ G L ++L T LL A IA GM YL
Sbjct: 913 NHPNVVKILGVISEPEVCLVMEYVKHGSLQSYLAIHKQELTHRRLLGFALDIATGMDYLG 972
Query: 809 SLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRG 868
S VHRDLAARN L+ ++KISDFG DYY + LP++W A ES+ G
Sbjct: 973 SEGIVHRDLAARNILVADENKVKISDFGLAQVIGENDYYILQTDRSLPIKWYAPESIRDG 1032
Query: 869 KYTTKSDVWAFAVTLHEIYSLCRRRPYEHL-TDCEVLDNLSHLQADD--GMFECVDRAP- 924
K++ +SDVW+F VT++E +S L + E L N + + E R P
Sbjct: 1033 KFSIRSDVWSFGVTMYETFSFGEEPRLPGLDSSTERLQNEQEKGSTELLAALENGIRLPC 1092
Query: 925 --GCPRDLY-ELMLECWRRDELDRPTFGEI 951
CP+ +Y +LM CW RP F +
Sbjct: 1093 PFTCPQAIYVKLMHPCWNLKSHKRPDFATL 1122
Score = 57.2 bits (132), Expect = 2e-06
Identities = 57/234 (24%), Positives = 104/234 (44%), Gaps = 30/234 (12%)
Query: 715 ITSEKRL-VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYL 773
+T K+L VA+K L + +EF + L S L R+ G +P + ++LE +
Sbjct: 457 LTKGKKLEVALKILKQEEEANYTKEFLELAGKWSQLRSGTLVRLYGLTVTPSIGMLLELV 516
Query: 774 ELGDLCAFLRAAIPPTAAT--LLHIATQIAAGMQYLESLNFVHRDLAARNCLI----GKG 827
G L +LR++ T T ++ +AA + +LE VH ++ L+
Sbjct: 517 RHGSLDEYLRSSSSQTIKTVDMVEATACLAAALWHLEENGVVHGNIRCNKLLVHAHTNNS 576
Query: 828 YQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIY 887
+ +K++D G YT ++D P + + +++ ++D+WA T+ +I+
Sbjct: 577 FVVKLADPGIF--VYT----EMDIHWLPP---ETYNDLELARHSFQADIWAVGTTIWQIF 627
Query: 888 SLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAP---GCPRDLYELMLECW 938
+ + L S++ +E R P GCP ++Y LMLECW
Sbjct: 628 ARG-----------DTLQEFSNVTIVKKHYEAGKRLPIPNGCPTEVYRLMLECW 670
>UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3)
(DRT) (Receptor protein-tyrosine kinase HEK5) (ERK)
(Renal carcinoma antigen NY-REN-47).; n=1; Takifugu
rubripes|Rep: Ephrin type-B receptor 2 precursor (EC
2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT)
(Receptor protein-tyrosine kinase HEK5) (ERK) (Renal
carcinoma antigen NY-REN-47). - Takifugu rubripes
Length = 986
Score = 136 bits (330), Expect = 2e-30
Identities = 83/235 (35%), Positives = 133/235 (56%), Gaps = 16/235 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L T K+R +F + I+ P++ + G +S P+ ++ E++E G L A
Sbjct: 671 VAIKTLKTGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDA 730
Query: 781 FLRAAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN- 839
FLR +I L+ + IA+GM+YL +N+VHRDLAARN L+ K+SDFG
Sbjct: 731 FLRVSIH--GDQLVGMLRGIASGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRF 788
Query: 840 -EAYTCD--YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
E T D Y G +P+RW A E++ K+T+ SDVW++ + + E+ S RPY
Sbjct: 789 LEDDTSDPTYTSALGG-KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY-GERPYW 846
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+T+ +V ++ ++ D + +D CP L++LML+CW++D +RP F +I
Sbjct: 847 DMTNQDV---INAIEQDYRLPPPMD----CPSTLHQLMLDCWQKDRNNRPKFSQI 894
>UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2;
Culicidae|Rep: Tyrosine protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 722
Score = 136 bits (330), Expect = 2e-30
Identities = 92/297 (30%), Positives = 150/297 (50%), Gaps = 31/297 (10%)
Query: 673 LETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDAT 732
+ T + E P+ R+ + +L EGAFGTVY EA E A VAVK L +T
Sbjct: 280 VNTLDKWEVPKDRVVINRRLGEGAFGTVYGGEAQIGDEGWTA-------VAVKTLKIGST 332
Query: 733 LKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA------ 785
+++ +F + + ++ ++LG C ++ P+ ++E++ GDL +L A
Sbjct: 333 TEDKVDFLSEAEAMKRFDHNNIVKLLGVCLQTEPVYTIMEFMLYGDLKTYLLARRHLVNS 392
Query: 786 -------IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD 838
I P T++ A ++ + YL +VHRDLA RNC++ +K+ DFG
Sbjct: 393 KQSEDSDISPKRLTMM--ALDVSRALSYLAEQKYVHRDLACRNCMVNAQRVVKLGDFGMA 450
Query: 839 NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
+ DYY+ + + LP+RW A ES+ G +T SDVW++ V L+EI S PY+ +
Sbjct: 451 RPTFENDYYRFNRKGMLPVRWMAPESLALGIFTPASDVWSYGVLLYEIISF-GSFPYQGM 509
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
T+ +VL+++ +G C+ G L LM CW +D RP+ E+ F+
Sbjct: 510 TNNQVLEHVK-----EG--NCLTIPTGVKPQLEGLMKACWNQDYKKRPSASEVSEFI 559
>UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3;
Culicidae|Rep: Protein kinase protein - Aedes aegypti
(Yellowfever mosquito)
Length = 1081
Score = 136 bits (330), Expect = 2e-30
Identities = 95/272 (34%), Positives = 136/272 (50%), Gaps = 18/272 (6%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER--EEFERDVRI 745
M KL +G+FG V E + G I VAVK L D + E+F ++V+
Sbjct: 121 MSVKLGDGSFGVVRRGEWNAP---GGQIVP----VAVKILKADTLAQPGVIEDFFKEVQA 173
Query: 746 LAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLL-HIATQIAAGM 804
+ L+ P+L R+ G S P+ +V E G L LR T+ T + + + Q+A GM
Sbjct: 174 MHTLNHPNLVRLHGVVLSQPMMMVTELAANGSLLDTLRKQCKNTSLTTIWNWSVQVATGM 233
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWAAWE 863
YLES F+HRDLA RN L+ G +IKI DFG D Y + +P W A E
Sbjct: 234 AYLESKRFLHRDLACRNVLLASGNKIKIGDFGLMRALPQQEDCYVMTEHKKVPFPWCAPE 293
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
S+ +++ SD W FAVTL E+++ P+ L ++L + D E +
Sbjct: 294 SLRYRQFSHASDTWMFAVTLWEMFTF-GEDPWVGLNGSQILRKI------DREGERLHHP 346
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
CP D+Y+LML+CW + +RPTF I FL
Sbjct: 347 DACPPDVYQLMLQCWDKSPAERPTFAAIKEFL 378
>UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n=2;
Ascidiacea|Rep: Gamma-carboxyglutamic acid protein 1 -
Ciona intestinalis (Transparent sea squirt)
Length = 556
Score = 136 bits (330), Expect = 2e-30
Identities = 93/281 (33%), Positives = 141/281 (50%), Gaps = 31/281 (11%)
Query: 683 RHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRL---VAVKFLCHDATLKEREEF 739
R RL++ + G FG VY G + S + VAVK L ++ E+F
Sbjct: 169 RERLQLGEVITSGNFGDVY----------RGKLRSRQNTWHDVAVKSLKSLENHEDVEKF 218
Query: 740 ERDVRILAALSSPHLARVLGAC--------RSPPLAVVLEYLELGDLCAFLRAAIPP-TA 790
R+ ++ L ++ ++G C ++ PL ++L ++E GDL FLR T
Sbjct: 219 LREGVMMRGLDHRNVLALIGVCVDGEVERLQTSPL-IILPFMENGDLRTFLRDGNNVLTV 277
Query: 791 ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVD 850
LL +A GM+YL FVHRDLAARNC++ K + +K++DFG + + DYY+
Sbjct: 278 LKLLKFCKDVAMGMEYLAEKKFVHRDLAARNCMVDKNWCVKVADFGLSRDLFDRDYYRSS 337
Query: 851 GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHL 910
+ LPL+W ES+ G+Y KSDVW++ + EI + PY + +L LS
Sbjct: 338 VKTQLPLKWMPPESIKYGRYGEKSDVWSYGIVCWEIMTR-GAIPYPTVQAVAILQYLS-- 394
Query: 911 QADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+G ++R CP LY+ M +CW D RPTF E+
Sbjct: 395 ---EG--NRMERPECCPHKLYKTMEKCWLDDTERRPTFEEL 430
>UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 337
Score = 136 bits (330), Expect = 2e-30
Identities = 99/285 (34%), Positives = 144/285 (50%), Gaps = 30/285 (10%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
+ GAFG V A G+P G +++ +VAVK L AT+++R F ++ ++ L
Sbjct: 24 VGSGAFGKVTKATIVGLP---GGPENKETVVAVKKLNAMATMEDRRNFLSEIEMMKQLGK 80
Query: 752 P-HLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAA-------------IPPTAAT---L 793
++ +LG + L ++ EY GDL +LRA P T L
Sbjct: 81 HLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAPGRELTQNDL 140
Query: 794 LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAY-TCDYYKVDGR 852
L A QIA GM+YL FVHRDLAARN LI + +KISDFG + Y + +Y+K+
Sbjct: 141 LSFARQIAVGMEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTRDVYESSEYHKMHNT 200
Query: 853 VPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
LPL+W A E++ + +TTKSDVWAF V L EI +L PY + E L +
Sbjct: 201 GKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTL-GGSPYPGQSGKEFYKKLKNGYR 259
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
+++ C +LY +M CW DRPTF ++ L++
Sbjct: 260 -------MEKPDMCSPELYAMMRSCWASSPEDRPTFTKLRNQLEQ 297
>UniRef50_O60674 Cluster: Tyrosine-protein kinase JAK2; n=48;
Euteleostomi|Rep: Tyrosine-protein kinase JAK2 - Homo
sapiens (Human)
Length = 1132
Score = 136 bits (330), Expect = 2e-30
Identities = 94/309 (30%), Positives = 155/309 (50%), Gaps = 25/309 (8%)
Query: 660 PSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEK 719
P+ + L E + +F L+ + +L +G FG+V + D + + G +
Sbjct: 823 PNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEV---- 878
Query: 720 RLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPP---LAVVLEYLELG 776
VAVK L H +T + +FER++ IL +L ++ + G C S L +++EYL G
Sbjct: 879 --VAVKKLQH-STEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYG 935
Query: 777 DLCAFLRAAIPPTA-ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDF 835
L +L+ LL +QI GM+YL + ++HRDLA RN L+ ++KI DF
Sbjct: 936 SLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDF 995
Query: 836 G-TDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR- 893
G T +YYKV P+ W A ES+ K++ SDVW+F V L+E+++ +
Sbjct: 996 GLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSK 1055
Query: 894 --PYEHL----TDCE---VLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELD 944
P E + D + ++ +L L ++G + R GCP ++Y +M ECW +
Sbjct: 1056 SPPAEFMRMIGNDKQGQMIVFHLIELLKNNGR---LPRPDGCPDEIYMIMTECWNNNVNQ 1112
Query: 945 RPTFGEIHL 953
RP+F ++ L
Sbjct: 1113 RPSFRDLAL 1121
Score = 41.9 bits (94), Expect = 0.080
Identities = 54/208 (25%), Positives = 83/208 (39%), Gaps = 21/208 (10%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L +G F ++ V +Y +E V +K L A E F +++ LS
Sbjct: 551 LGQGTFTKIFKGVRREVGDYGQLHETE---VLLKVL-DKAHRNYSESFFEAASMMSKLSH 606
Query: 752 PHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQYLES 809
HL G C +V E+++ G L +L+ L +A Q+A M +LE
Sbjct: 607 KHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEE 666
Query: 810 LNFVHRDLAARNCLI--------GKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAA 861
+H ++ A+N L+ G IK+SD G D + R+P W
Sbjct: 667 NTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDI--LQERIP----WVP 720
Query: 862 WESVLRGK-YTTKSDVWAFAVTLHEIYS 888
E + K +D W+F TL EI S
Sbjct: 721 PECIENPKNLNLATDKWSFGTTLWEICS 748
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 136 bits (330), Expect = 2e-30
Identities = 80/243 (32%), Positives = 131/243 (53%), Gaps = 12/243 (4%)
Query: 711 YNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVV 769
Y G + +K VAVK D + + +F ++ +IL P++ +++G C + P+ ++
Sbjct: 578 YKGTL-KDKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYII 636
Query: 770 LEYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGY 828
+E + GD FLR L+ + AAGM YLES N +HRDLAARNCL+G+
Sbjct: 637 MELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENN 696
Query: 829 QIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
+KISDFG + Y G +P++W A E++ G+Y+++SDVW+F + L E +S
Sbjct: 697 VLKISDFGMSRQE-DGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFS 755
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
L PY +T+ + + Q + G + CP D+ ++M++CW +RP F
Sbjct: 756 L-GVCPYPGMTNQQARE-----QVERGY--RMSAPQHCPEDISKIMMKCWDYKPENRPKF 807
Query: 949 GEI 951
E+
Sbjct: 808 SEL 810
>UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=311;
Eumetazoa|Rep: Ephrin type-B receptor 2 precursor - Homo
sapiens (Human)
Length = 1055
Score = 136 bits (330), Expect = 2e-30
Identities = 84/236 (35%), Positives = 132/236 (55%), Gaps = 15/236 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L T K+R +F + I+ P++ + G +S P+ ++ E++E G L +
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
FLR T L+ + IAAGM+YL +N+VHRDLAARN L+ K+SDFG
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
Query: 840 --EAYTCD--YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPY 895
E T D Y G +P+RW A E++ K+T+ SDVW++ + + E+ S RPY
Sbjct: 770 FLEDDTSDPTYTSALGG-KIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSY-GERPY 827
Query: 896 EHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+T+ +V ++ ++ D + +D CP L++LML+CW++D RP FG+I
Sbjct: 828 WDMTNQDV---INAIEQDYRLPPPMD----CPSALHQLMLDCWQKDRNHRPKFGQI 876
>UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 1193
Score = 136 bits (329), Expect = 3e-30
Identities = 94/281 (33%), Positives = 144/281 (51%), Gaps = 18/281 (6%)
Query: 674 ETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHD-AT 732
+ T +I P L L GAFGTVY + PE + VA+K L + AT
Sbjct: 829 DATRLIITPETALEQGQVLGSGAFGTVY--KGHWRPEGDPNCYE----VAIKVLKEETAT 882
Query: 733 LKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRA-AIPPTAA 791
+ + E R+ ++A + ++ R+ C + ++ E++ LG L ++L+ A
Sbjct: 883 PQSQTELLREGAVMATMDHINVVRLYCVCMGKQMMLITEFVRLGSLLSYLKNNQATLDAY 942
Query: 792 TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD-YYKVD 850
++L+ + QIA GM YLE VHRDLAARN L+ +KI+DFG + +YK
Sbjct: 943 SMLNFSRQIADGMAYLEEKRMVHRDLAARNVLVHTPQLVKITDFGLTRIIDVGESHYKAT 1002
Query: 851 GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHL 910
G + +PLRW A ES+ +YT KSDVW+F VT+ EI + R PY+ EV + +
Sbjct: 1003 GGM-VPLRWMAPESIFLFEYTHKSDVWSFGVTIWEILTF-GRLPYKGKNGKEVSQLVKNG 1060
Query: 911 QADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
Q ++R C +LY L+ +CW D+ RP+F +
Sbjct: 1061 QQ-------LERPATCDANLYHLLEQCWLHDQTKRPSFSAL 1094
>UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 276
Score = 136 bits (329), Expect = 3e-30
Identities = 96/266 (36%), Positives = 141/266 (53%), Gaps = 28/266 (10%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EGAFG V+ G NG + VAVK L +A +EREEF R+++++ +
Sbjct: 3 LGEGAFGQVFKGILRGP---NGQVIP----VAVKQLKANAIDEEREEFVREIQMMQTVGQ 55
Query: 752 -PHLARVLGACRSPPL-AVVLEYLELGDLCAFLR-------AAIPPTAATLLHIATQIAA 802
++ + G C L +++EY+ GDL +L+ + + L QIA
Sbjct: 56 HDNIVTMYGYCMDEQLQCMIMEYVPYGDLKHYLQNMRKEKDSDSAIDSKEFLSFTNQIAC 115
Query: 803 GMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAW 862
GM +LES+ +HRDLAARN L+G G +KISDFG Y K+ V +PLRW +
Sbjct: 116 GMAHLESVGIIHRDLAARNILVGTGKVLKISDFGMSRPGV---YIKMSKGV-IPLRWLSP 171
Query: 863 ESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDR 922
E++ Y+ KSDVWAF V L EI +L PY ++ D ++L+ L+ +GM +++
Sbjct: 172 EAIKDNTYSNKSDVWAFGVLLWEIATL-GGFPYNNVADKDILNQLT-----EGM--RLEQ 223
Query: 923 APGCPRDLYELMLECWRRDELDRPTF 948
C D+Y LM CW DRP+F
Sbjct: 224 PAKCSDDMYILMKSCWNLKAEDRPSF 249
>UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase
erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine
kinase-type cell surface receptor HER4).; n=1; Takifugu
rubripes|Rep: Receptor tyrosine-protein kinase erbB-4
precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine
kinase-type cell surface receptor HER4). - Takifugu
rubripes
Length = 1236
Score = 136 bits (328), Expect = 4e-30
Identities = 94/268 (35%), Positives = 138/268 (51%), Gaps = 17/268 (6%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
L+ + L GAFGTVY + VPE K VAVK L K EF + I
Sbjct: 670 LKRVKVLGSGAFGTVY--KGIWVPEGEKV----KIPVAVKILNEATGPKANVEFMDEALI 723
Query: 746 LAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLL-HIATQIAAGM 804
+A++ PHL R+LG C SP + +V + + G L ++ + LL + QIA GM
Sbjct: 724 MASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGM 783
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD-YYKVDGRVPLPLRWAAWE 863
YLE VHRDLAARN L+ IKI+DFG + Y DG + ++W A E
Sbjct: 784 MYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLDVNEKEYNADGG-KMAIKWMALE 842
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
+ K+T +SDVW++ VT+ E+ + +PY+ ++ ++ D L + G E + +
Sbjct: 843 CIHYRKFTHQSDVWSYGVTIWELMTF-GGKPYDGISTRDIPDLL-----EKG--ERLPQP 894
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
P C D+Y +M++CW D RP F E+
Sbjct: 895 PICTIDVYMVMVKCWMIDADSRPKFKEL 922
>UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus
variegatus|Rep: Focal adhesion kinase - Lytechinus
variegatus (Sea urchin)
Length = 1006
Score = 136 bits (328), Expect = 4e-30
Identities = 91/299 (30%), Positives = 147/299 (49%), Gaps = 18/299 (6%)
Query: 654 KQSTRSPSQQEILLDLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNG 713
K S S EI+ D + E R + ++ + +G FG V+ G+ Y
Sbjct: 406 KPSGLSDDYAEIVDDDDYAMPAAKDYEISRELVTLVETIGQGQFGDVH----KGI--YID 459
Query: 714 AITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYL 773
EK VAVK ++T E F + I+ PH+ +++G C PP+ +V+E
Sbjct: 460 Q--DEKVEVAVKTCKVESTQALGERFLEEAYIMKQFDHPHIIKLIGVCTDPPIWIVMELA 517
Query: 774 ELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKI 832
G++ FL+ T A+L+ A Q++ + YLES FVHRD+AARN L+ +K+
Sbjct: 518 PFGEMRMFLQTHKEELTLASLILYAYQLSMALSYLESKKFVHRDIAARNLLVVAKDNVKL 577
Query: 833 SDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRR 892
DFG + YYK + LP++W A ES+ ++T+ SDVW F V + EI +
Sbjct: 578 GDFGLSRLLHDHSYYKA-SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL-MYGV 635
Query: 893 RPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+P++ + + EV+ + ++G E + CP LY +M CW + RP F ++
Sbjct: 636 KPFQGVKNNEVIGRI-----ENG--ERLPMPAACPPTLYSVMTLCWSYEPSKRPNFKDL 687
>UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 337
Score = 136 bits (328), Expect = 4e-30
Identities = 100/292 (34%), Positives = 146/292 (50%), Gaps = 31/292 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHD-----ATLK 734
EFP RL + L +GAFG V AEA G+ +N S L + A+
Sbjct: 26 EFPEERLILGKVLGQGAFGQVLRAEAIGMDNFNPRDKSADGLKTRSKMRRSLRGKGASES 85
Query: 735 EREEFERDVRILAALSS-PHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRA---AIPPT 789
+ ++ +++IL L ++ VLGAC R L V++E+ G+L +FLRA PT
Sbjct: 86 DYKDLASELKILIHLGEHKNIVNVLGACTRGRRLMVIIEFAPYGNLLSFLRARREVYQPT 145
Query: 790 AA----------TLLHIAT---QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG 836
TL+ + Q++ G+++L S VHRDLAARN L+G Y +K+SDFG
Sbjct: 146 WTKTTNDPEKNYTLVDLTMASYQVSRGVEFLASRKCVHRDLAARNVLVGPDYVMKVSDFG 205
Query: 837 TDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ Y D Y + LP++W A ES+ YT KSDVW+F + L EI +L PY
Sbjct: 206 LARDIYQDDLYVKNTSGLLPVKWMALESLFDRVYTEKSDVWSFGILLWEIMTL-GGTPYP 264
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
L ++LD LS Q + + CP ++Y +M +CW + RP F
Sbjct: 265 GLPTEQLLDYLSEGQR-------MAQPQNCPLEIYTIMRDCWMQLPEQRPHF 309
>UniRef50_P00533 Cluster: Epidermal growth factor receptor
precursor; n=124; root|Rep: Epidermal growth factor
receptor precursor - Homo sapiens (Human)
Length = 1210
Score = 135 bits (327), Expect = 5e-30
Identities = 90/268 (33%), Positives = 141/268 (52%), Gaps = 19/268 (7%)
Query: 687 RMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRIL 746
+ I L GAFGTVY + +PE K VA+K L + K +E + ++
Sbjct: 713 KKIKVLGSGAFGTVY--KGLWIPEGEKV----KIPVAIKELREATSPKANKEILDEAYVM 766
Query: 747 AALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGMQ 805
A++ +PH+ R+LG C + + ++ + + G L ++R + LL+ QIA GM
Sbjct: 767 ASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMN 826
Query: 806 YLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN--EAYTCDYYKVDGRVPLPLRWAAWE 863
YLE VHRDLAARN L+ +KI+DFG A +Y+ G+V P++W A E
Sbjct: 827 YLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKV--PIKWMALE 884
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
S+L YT +SDVW++ VT+ E+ + +PY+ + E+ L + G E + +
Sbjct: 885 SILHRIYTHQSDVWSYGVTVWELMTF-GSKPYDGIPASEISSIL-----EKG--ERLPQP 936
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
P C D+Y +M++CW D RP F E+
Sbjct: 937 PICTIDVYMIMVKCWMIDADSRPKFREL 964
>UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosine
kinase, non-recepTor, 2 isoform 1; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Tyrosine kinase,
non-recepTor, 2 isoform 1 - Takifugu rubripes
Length = 767
Score = 135 bits (326), Expect = 6e-30
Identities = 77/220 (35%), Positives = 119/220 (54%), Gaps = 9/220 (4%)
Query: 738 EFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAA-IPPTAATLLHI 796
+F ++V + AL P++ R+ G + PL +V E LG L LRA L
Sbjct: 184 DFLQEVTTMQALDHPNIIRLYGVVLTQPLKMVTELASLGSLYDTLRARQFEYPLVRLWLF 243
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG-TDNEAYTCDYYKVDGRVPL 855
ATQIA+GM YLE+ +HRDLAARN L+ +KI DFG + D+Y + +
Sbjct: 244 ATQIASGMDYLETRRLIHRDLAARNILLASREMVKIGDFGLMRGLSQEVDHYVMSAHRRI 303
Query: 856 PLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDG 915
P W A ES+ G ++ SDVW F VT+ E+++ C P+ LT ++L + +G
Sbjct: 304 PFAWCAPESLRVGSFSHSSDVWMFGVTMWEMFTYC-EEPWFGLTGRQILWRVER----EG 358
Query: 916 MFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
E +++ P CP++LY +M +CW + DRP F ++ + +
Sbjct: 359 --ERLEKPPDCPQELYVVMRKCWACNPNDRPNFSQLGMLV 396
>UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 780
Score = 135 bits (326), Expect = 6e-30
Identities = 84/240 (35%), Positives = 131/240 (54%), Gaps = 13/240 (5%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L T K++ +F + I+A P++ R+ G S P+ ++ EY+E G L +
Sbjct: 444 VALKTLKVGYTEKQKRDFLAEASIMAQFDHPNVIRLEGVVTHSKPVMIITEYMENGSLDS 503
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
FLR T L+ + IAAGM YL L ++HRDLAARN L+ K+SDFG
Sbjct: 504 FLRRHDGQFTIIQLVGLLRGIAAGMTYLSDLGYIHRDLAARNILVNSNLVCKVSDFGLSR 563
Query: 840 --EAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
E Y G +P+RW A E++ K+++ SDVW++ V + E+ S RPY +
Sbjct: 564 VLEDDPDAAYTTSGG-KIPIRWTAPEAITFRKFSSSSDVWSYGVVMWEVTSY-GERPYWN 621
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
LT+ +V+ ++ ++G + GCP L+ LML+CW++D +RP F +I L +
Sbjct: 622 LTNRDVIKSV-----EEGY--RLPAPMGCPAALHTLMLDCWQKDRNERPRFCQIVTVLDK 674
>UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor (EC
2.7.10.1) (ILP receptor) [Contains: Insulin-like peptide
receptor alpha chain; Insulin-like peptide receptor beta
chain]; n=4; Eukaryota|Rep: Insulin-like peptide receptor
precursor (EC 2.7.10.1) (ILP receptor) [Contains:
Insulin-like peptide receptor alpha chain; Insulin-like
peptide receptor beta chain] - Branchiostoma lanceolatum
(Common lancelet) (Amphioxus)
Length = 1363
Score = 135 bits (326), Expect = 6e-30
Identities = 70/166 (42%), Positives = 100/166 (60%), Gaps = 8/166 (4%)
Query: 786 IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCD 845
+PPT ++ +A IA GM YL + FVHRDLA RNC++ + +KI DFG + Y D
Sbjct: 1118 LPPTFKDIIQMAGVIADGMSYLAAKKFVHRDLACRNCMVAQDRTVKIGDFGMTRDIYETD 1177
Query: 846 YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLD 905
YY+ G+ LP+RW + ES+ G +T++SDVW++ V L E+ +L +PY+ ++ EVL
Sbjct: 1178 YYRKGGKGLLPVRWMSPESLKVGVFTSQSDVWSYGVVLWEMATLA-SQPYQGKSNEEVL- 1235
Query: 906 NLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D GM E + GCP LY+LM CW+ + RPTF EI
Sbjct: 1236 ---KFVIDGGMLE---KPEGCPNKLYDLMKLCWQYRQSMRPTFLEI 1275
Score = 62.1 bits (144), Expect = 7e-08
Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 6/109 (5%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR ++ +I +L +G+FG VY EA V + ++ VAVK + A+++ER EF
Sbjct: 988 EVPREKITLIRELGQGSFGMVYEGEAKDVVKDEPMVS-----VAVKTVNESASIRERIEF 1042
Query: 740 ERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIP 787
+ ++ + H+ +++G + P VV+E + LGDL +LR P
Sbjct: 1043 LNEASVMKTFNCHHVVKLMGVVSKGQPTLVVMELMALGDLKNYLRRHRP 1091
>UniRef50_UPI0000D563AD Cluster: PREDICTED: similar to CG3969-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3969-PA, isoform A - Tribolium castaneum
Length = 1268
Score = 134 bits (325), Expect = 8e-30
Identities = 86/243 (35%), Positives = 124/243 (51%), Gaps = 15/243 (6%)
Query: 718 EKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGD 777
E+ VA+K L D EF ++ I+ + P++ R G ++ EL
Sbjct: 147 ERIQVAIKCLSRDRMQSNMVEFLKEASIMHNIDHPNIVRFFGVVLPNVEGSLMLVTELAP 206
Query: 778 LCAFLRAAIPPT------AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIK 831
L + L P+ TL A QI GMQYLE+ +HRDLAARN L+ ++K
Sbjct: 207 LRSLLECLKEPSLRSSFPVLTLCDFAYQICDGMQYLEANRLIHRDLAARNILVFSKSKVK 266
Query: 832 ISDFGTDNE-AYTCDYYKVDGRV--PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
ISDFG DYY+ + V LP+ W A E + ++TT SDVWAF VTL E++S
Sbjct: 267 ISDFGLSRALGQGKDYYQTNFNVNLKLPIAWCAPECISYLRFTTSSDVWAFGVTLWEMFS 326
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+P+ LT ++L+ + D+ F+ +++ CP D Y LML+CWR + RP F
Sbjct: 327 Y-GFQPWAALTGQQILEAI-----DEPNFQRLEQPDCCPLDHYNLMLDCWRHEASARPKF 380
Query: 949 GEI 951
EI
Sbjct: 381 AEI 383
>UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephrin
receptor - Gallus gallus (Chicken)
Length = 969
Score = 134 bits (325), Expect = 8e-30
Identities = 94/276 (34%), Positives = 141/276 (51%), Gaps = 20/276 (7%)
Query: 688 MISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILA 747
M + + EG FG VY G G E+ +VA+K L + + F R+ I+
Sbjct: 618 MENVIGEGEFGEVY----RGSLRLPG---KERIVVAIKTLKSTYSDSQWWNFLREATIMG 670
Query: 748 ALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAAGMQ 805
+ P++ + G + P+ ++ EY+E G L FLR + L+++ IA+GM
Sbjct: 671 QFNHPNIVHLEGVVTKRRPMMIITEYMENGALDTFLRENEEKFSPVQLVNMLQGIASGMT 730
Query: 806 YLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN--EAYTCDYYKVDGRVPLPLRWAAWE 863
YL N+VHRDLAARN L+ + Q K+SDFG E Y+ G +P+RW A E
Sbjct: 731 YLSEHNYVHRDLAARNILVTRSLQCKVSDFGLSRILENDAEGTYETKGG-KIPIRWTAPE 789
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
++ +T+ SDVW+F + + E+ S +PY ++T+ EV+ +L +DG +
Sbjct: 790 AIAHRIFTSASDVWSFGIVMWEVLSF-GDKPYGNMTNQEVMKSL-----EDGY--RLPPP 841
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEIHLFLQRKS 959
CP LYELM CW D + RP F EI LQ S
Sbjct: 842 VDCPSILYELMKSCWSHDRMRRPHFQEIRAQLQHFS 877
>UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111;
Euteleostomi|Rep: Focal adhesion kinase 1 - Homo sapiens
(Human)
Length = 1052
Score = 134 bits (325), Expect = 8e-30
Identities = 89/281 (31%), Positives = 144/281 (51%), Gaps = 19/281 (6%)
Query: 673 LETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDAT 732
+ +T E R R+ + + EG FG V+ PE N A+ VA+K C + T
Sbjct: 409 MPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMS-PE-NPALA-----VAIK-TCKNCT 460
Query: 733 LKE-REEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAA-IPPTA 790
RE+F ++ + PH+ +++G P+ +++E LG+L +FL+
Sbjct: 461 SDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDL 520
Query: 791 ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVD 850
A+L+ A Q++ + YLES FVHRD+AARN L+ +K+ DFG YYK
Sbjct: 521 ASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKA- 579
Query: 851 GRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHL 910
+ LP++W A ES+ ++T+ SDVW F V + EI + +P++ + + +V+ +
Sbjct: 580 SKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEIL-MHGVKPFQGVKNNDVIGRI--- 635
Query: 911 QADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++G E + P CP LY LM +CW D RP F E+
Sbjct: 636 --ENG--ERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTEL 672
>UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming
protein erbB; n=8; root|Rep: Tyrosine-protein kinase
transforming protein erbB - Avian leukosis virus (ALV)
Length = 634
Score = 134 bits (325), Expect = 8e-30
Identities = 89/268 (33%), Positives = 141/268 (52%), Gaps = 19/268 (7%)
Query: 687 RMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRIL 746
+ + L GAFGTVY + +PE K VA+K L + K +E + ++
Sbjct: 133 KKVKVLGSGAFGTVY--KGLWIPEGEKV----KIPVAIKELREATSPKANKEILDEAYVM 186
Query: 747 AALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHIATQIAAGMQ 805
A++ +PH+ R+LG C + + ++ + + G L ++R + LL+ QIA GM
Sbjct: 187 ASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMN 246
Query: 806 YLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN--EAYTCDYYKVDGRVPLPLRWAAWE 863
YLE VHRDLAARN L+ +KI+DFG A +Y+ G+V P++W A E
Sbjct: 247 YLEERRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHAEGGKV--PIKWMALE 304
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
S+L YT +SDVW++ VT+ E+ + +PY+ + E+ L + G E + +
Sbjct: 305 SILHRIYTHQSDVWSYGVTVWELMTF-GSKPYDGIPASEISSVL-----EKG--ERLPQP 356
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
P C D+Y +M++CW D RP F E+
Sbjct: 357 PICTIDVYMIMVKCWMIDADSRPKFREL 384
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 134 bits (324), Expect = 1e-29
Identities = 81/231 (35%), Positives = 131/231 (56%), Gaps = 13/231 (5%)
Query: 720 RLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDL 778
R +A++ L H+ L E ++F +V+++ LS P+L ++ G R PL +V+EYL LG L
Sbjct: 401 RHIAIRML-HEGVLAE-DDFFHEVKLMMQLSHPNLVQLYGVVTRYRPLRIVMEYLALGCL 458
Query: 779 CAFLRAAIPPT-AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
FL+A +A LL + + M YLES +F+HRDLAAR+CL+G+ + IK+SDFG
Sbjct: 459 RTFLQARPGKLGSAWLLEACSDVCKAMVYLESNSFLHRDLAARHCLVGEDFSIKVSDFGM 518
Query: 838 DNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
D Y P++W+ E RG++++KSDVW+F V + E++S PY+
Sbjct: 519 ARYVLD-DQYTCSQGARFPVKWSPPEVFDRGRFSSKSDVWSFGVVMWEVFSE-GTLPYDG 576
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
++ EV++++ H + + P +Y +M +CW+ D RP F
Sbjct: 577 WSNGEVVESV-HAGYQ------LPQPTLAPTPVYTIMCDCWQPDPEKRPYF 620
>UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Rep:
Ephrin receptor - Tetraodon nigroviridis (Green puffer)
Length = 1006
Score = 134 bits (324), Expect = 1e-29
Identities = 89/257 (34%), Positives = 136/257 (52%), Gaps = 24/257 (9%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L + K+R +F + I+ P++ R+ G R PL ++ EY+E G L A
Sbjct: 690 VAIKSLKAGYSDKQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPLMIITEYMENGSLDA 749
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG--- 836
FLR T L+ + IA+GM+YL +++VHRDLAARN L+ K+SDFG
Sbjct: 750 FLRKHDGQFTVIQLVGMLRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGLSR 809
Query: 837 ---TDNE-AYTC-----DYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIY 887
D E AYT Y G++ P+RW A E++ K+TT SDVW++ + + E+
Sbjct: 810 VLEDDPEAAYTTRENTGTYLSPGGKI--PIRWTAPEAIAYRKFTTASDVWSYGIVMWEVV 867
Query: 888 SLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPT 947
S RPY + + +V+ + ++G + CP L++LML+CW R+ +RPT
Sbjct: 868 SY-GERPYWDMNNQDVIKAI-----EEGY--RLPAPMDCPLVLHQLMLDCWERERAERPT 919
Query: 948 FGEIHLFLQRKSLNYAT 964
F +I L + N T
Sbjct: 920 FSQILNMLDKLIRNPGT 936
>UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:
ENSANGP00000009263 - Anopheles gambiae str. PEST
Length = 1306
Score = 134 bits (324), Expect = 1e-29
Identities = 85/247 (34%), Positives = 130/247 (52%), Gaps = 14/247 (5%)
Query: 717 SEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLEL 775
SE+ VA+K LC + EF ++ ++ ++ ++ R+ G + L +V E L
Sbjct: 143 SERIQVAIKCLCRERMQSNPMEFLKEAAMMHSIEHENIVRLYGVVLDTESLMLVTELAHL 202
Query: 776 GDLCAFLR----AAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIK 831
L L+ T TL A+QI GM YLE+ F+HRDLAARN L+ ++K
Sbjct: 203 RSLLECLKDPGLRVSFLTVPTLCEFASQICNGMMYLENKRFIHRDLAARNILVFSKNKVK 262
Query: 832 ISDFGTDNE-AYTCDYYKVDGRV--PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
ISDFG DYY+ + V LP+ W A E + ++T SDVWAF V L EI+S
Sbjct: 263 ISDFGLSRALGVGKDYYQTNFNVNLKLPIAWCAPECINFLRFTHASDVWAFGVCLWEIFS 322
Query: 889 LCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
+P+ LT ++L+ + D+ ++ +++ CP++ Y LML+CW+ D RP F
Sbjct: 323 Y-GFQPWAALTGHQILEAI-----DEPHYQRLEKPECCPKEYYALMLKCWQHDAAKRPKF 376
Query: 949 GEIHLFL 955
+I L L
Sbjct: 377 SDIFLML 383
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 134 bits (324), Expect = 1e-29
Identities = 88/277 (31%), Positives = 140/277 (50%), Gaps = 16/277 (5%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E RLR+ +L G FG+V GV ++ VAVK L + ++ E
Sbjct: 351 ELDPKRLRLEHELGHGNFGSV----VKGVYLLKN---NKSVAVAVKTLKEEDIPGQKSEI 403
Query: 740 ERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLHIATQ 799
++ I++ L P++ R++G +SP +V+E G L FL+ +L + Q
Sbjct: 404 VKEAEIMSKLDHPNIVRLIGVTQSPGFMLVMELAPQGPLHKFLKKNRNMNVLDILVLMLQ 463
Query: 800 IAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLR 858
+ GM YLES +FVHRDLAARN L+ +KISDFG +YY+ + PL+
Sbjct: 464 VDEGMNYLESQHFVHRDLAARNVLVVSENFVKISDFGMSRAMGVGNEYYRAERAGKWPLK 523
Query: 859 WAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFE 918
W A E + K+++K DVW++ +T+ E S +PY+ + +++ L + G
Sbjct: 524 WYAPECIYYHKFSSKGDVWSYGITMWEAVSY-GGKPYQGMRGPVIVEKL-----ESGY-- 575
Query: 919 CVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+ + C +Y LML+CW + DRP+F EI + L
Sbjct: 576 RLPKPDNCSDAVYTLMLKCWETNPDDRPSFMEIGIIL 612
>UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2)
(EPH homology kinase 2).; n=2; Xenopus tropicalis|Rep:
Ephrin type-A receptor 6 precursor (EC 2.7.10.1)
(Tyrosine-protein kinase receptor EHK-2) (EPH homology
kinase 2). - Xenopus tropicalis
Length = 952
Score = 134 bits (323), Expect = 1e-29
Identities = 80/241 (33%), Positives = 132/241 (54%), Gaps = 15/241 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L ++R++F R+ I+ P++ R+ G +S P+ +V+EY+E G L +
Sbjct: 617 VAIKTLKGGYVDRQRKDFLREASIMGQFDHPNIIRLEGVVTKSRPVMIVVEYMENGSLDS 676
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD- 838
FLR T L+ + IA+GM+YL + +VHRDLAARN L+ K+SDFG
Sbjct: 677 FLRKHDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSR 736
Query: 839 --NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ Y G++ P+RW A E++ K+++ SD W++ + + E+ S RPY
Sbjct: 737 VLEDDPDAAYTTTGGKI--PIRWTAPEAIAFRKFSSASDAWSYGIVMWEVMSY-GERPYW 793
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+++ +V+ L ++G + GCP L++LML CW++D RP F +I FL
Sbjct: 794 EMSNQDVI-----LSIEEGY--RLPAPMGCPVSLHQLMLHCWQKDRNIRPKFSDIVGFLD 846
Query: 957 R 957
+
Sbjct: 847 K 847
>UniRef50_Q9PTN6 Cluster: Tyrosine-protein kinase; n=9;
Euteleostomi|Rep: Tyrosine-protein kinase - Cyprinus
carpio (Common carp)
Length = 1126
Score = 134 bits (323), Expect = 1e-29
Identities = 90/294 (30%), Positives = 151/294 (51%), Gaps = 20/294 (6%)
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
F LR IS L +G FG+V + D + G + + K L + K AT+ + F+
Sbjct: 816 FEERYLRFISILGKGNFGSVELCRYDPWGDNTGDLVAVKELQSNK----QATVTD---FQ 868
Query: 741 RDVRILAALSSPHLARVLGACRSP---PLAVVLEYLELGDLCAFLRAAIPPTAAT-LLHI 796
R+++ +++L ++ + G C S +V+EYL G L ++ LL
Sbjct: 869 REIQTISSLHCDYIVKYKGICYSTGRLSTKLVMEYLPYGSLIGYMEKHRQNVCTRRLLLF 928
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG-TDNEAYTCDYYKVDGRVPL 855
A+QI GM+YL+S+ +VHRDLAARN L+ +KI+DFG T +YY+V
Sbjct: 929 ASQICKGMEYLQSMRYVHRDLAARNILVASDTLVKIADFGLTKIIPVDKEYYRVTQPGES 988
Query: 856 PLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLC--RRRPYE--HLTDCEVLDNLSHLQ 911
P+ W A ES+ K++ KSD+W+F + LHE++S C R P + + D ++ +
Sbjct: 989 PVFWYAPESISELKFSHKSDIWSFGIVLHELFSYCDISRNPQKIVYPEDRKLCPEVRPWL 1048
Query: 912 ADDGMFECVD-RAPG---CPRDLYELMLECWRRDELDRPTFGEIHLFLQRKSLN 961
+ +F + R P CP ++ +M++CW + DRP+F + ++ L+
Sbjct: 1049 SIFLIFSKDNWRLPAPSQCPPKVHNIMMQCWEFNSEDRPSFSSLQDLIENSLLD 1102
Score = 50.4 bits (115), Expect = 2e-04
Identities = 42/161 (26%), Positives = 74/161 (45%), Gaps = 15/161 (9%)
Query: 737 EEFERDVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLLH 795
E F +++ +S HL V G + +V E+++ G L +L+ + + + L
Sbjct: 567 ESFFEAASLMSQISHKHLLLVYGISVHKSKNIMVQEFVKHGALDLYLKKSTSVSVSWKLD 626
Query: 796 IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQ--------IKISDFGTDNEAYTCDYY 847
+A Q+A + +LE N H ++ A+N L+ + IK+SD G + D
Sbjct: 627 VAKQLACALNFLEEKNIAHGNICAKNLLLAREGDPSTDNSPFIKLSDPGINMALLGKDV- 685
Query: 848 KVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYS 888
V R+P W A E + + + D W+F TL EI++
Sbjct: 686 -VLDRIP----WVAPEVLDTLEIELECDKWSFGTTLWEIFN 721
>UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=3; Fungi/Metazoa group|Rep:
Chromosome 3 SCAF14978, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 958
Score = 134 bits (323), Expect = 1e-29
Identities = 84/261 (32%), Positives = 133/261 (50%), Gaps = 18/261 (6%)
Query: 692 LAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRILAALSS 751
L EG FG V+ +GV + T E VA+K C + + +E+F + ++ L
Sbjct: 393 LGEGFFGEVH----NGVYKTQ---TGENLSVAIK-TCKNCSADVKEKFLSEASVMKNLDH 444
Query: 752 PHLARVLGACRSPPLAVVLEYLELGDLCAFL-RAAIPPTAATLLHIATQIAAGMQYLESL 810
PH+ R++G + P+ +V+E E G+L +L T L+ QI + YLE L
Sbjct: 445 PHIVRLIGVIEADPVWIVMELYEHGELGKYLVEQQYSLTTVMLITYCLQICKALAYLEGL 504
Query: 811 NFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKY 870
N VHRD+A RN L+ +K+ DFG +YYK LP++W A ES+ ++
Sbjct: 505 NVVHRDIAVRNILVASPLCVKLGDFGLSRYIEEEEYYKASAS-RLPIKWMAPESINFRRF 563
Query: 871 TTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDL 930
TT SDVW F V + EI+S+ ++P+ L + +V+D Q + G+ + + CP +
Sbjct: 564 TTASDVWMFGVCVWEIFSMA-QQPFFWLENSQVID-----QLESGI--RLPKPQLCPPTV 615
Query: 931 YELMLECWRRDELDRPTFGEI 951
Y L+ CW + RP F +
Sbjct: 616 YSLVSSCWSHEPHLRPQFSHL 636
>UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep:
Eph receptor B1 - Mus musculus (Mouse)
Length = 943
Score = 134 bits (323), Expect = 1e-29
Identities = 84/248 (33%), Positives = 136/248 (54%), Gaps = 13/248 (5%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L + K+R +F + I+ P++ R+ G +S P+ ++ E++E G L +
Sbjct: 607 VAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDS 666
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
FLR T L+ + IAAGM+YL +N+VHRDLAARN L+ K+SDFG
Sbjct: 667 FLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 726
Query: 840 --EAYTCD-YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ T D Y +P+RW A E++ K+T+ SDVW++ + + E+ S RPY
Sbjct: 727 YLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSF-GERPYW 785
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+++ +V ++ ++ D + +D CP L++LML+CW++D RP F EI L
Sbjct: 786 DMSNQDV---INAIEQDYRLPPPMD----CPAALHQLMLDCWQKDRNSRPRFAEIVNTLD 838
Query: 957 RKSLNYAT 964
+ N A+
Sbjct: 839 KMIRNPAS 846
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 134 bits (323), Expect = 1e-29
Identities = 88/284 (30%), Positives = 147/284 (51%), Gaps = 34/284 (11%)
Query: 674 ETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATL 733
+T + E R+ ++++ +L G FG V+ +G+ +N VAVK L +
Sbjct: 222 KTVDQWEIDRNSIQLLKRLGSGQFGEVW----EGL--WNNTTP-----VAVKTLKPGSM- 269
Query: 734 KEREEFERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLR--AAIPPTA 790
+ +F R+ +I+ L P L ++ C P+ ++ E + G L +L+
Sbjct: 270 -DPNDFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHL 328
Query: 791 ATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFG------TDNEAYTC 844
+ +A Q+A+GM YLES N++HRDLAARN L+G+ K++DFG DNE
Sbjct: 329 TQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNE---- 384
Query: 845 DYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVL 904
D Y+ + LP++W A E++ K++ KSDVW+F + L+EI + + PY +T +V+
Sbjct: 385 DIYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITY-GKMPYSGMTGAQVI 443
Query: 905 DNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
L+ + + CP+ Y +MLECW + +RPTF
Sbjct: 444 QMLAQNYR-------LPQPSNCPQQFYNIMLECWNAEPKERPTF 480
>UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep:
Ephrin receptor - Mus musculus (Mouse)
Length = 819
Score = 133 bits (322), Expect = 2e-29
Identities = 82/235 (34%), Positives = 125/235 (53%), Gaps = 15/235 (6%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L T K+R +F + I+ P++ + G +S P+ +V EY+E G L
Sbjct: 520 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 579
Query: 781 FLRAAIPP-TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTD- 838
FL+ T L+ + IAAGM+YL + +VHRDLAARN LI K+SDFG
Sbjct: 580 FLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 639
Query: 839 --NEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYE 896
+ Y G++ P+RW A E++ K+T+ SDVW++ + + E+ S RPY
Sbjct: 640 VLEDDPEAAYTTRGGKI--PIRWTAPEAIAFRKFTSSSDVWSYGIVMWEVVSY-GERPYW 696
Query: 897 HLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+T+ +V+ ++G + CP LY+LML+CW++D RP F EI
Sbjct: 697 EMTNQDVIK-----AVEEGY--RLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEI 744
>UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13;
Euteleostomi|Rep: Activated CDC42 kinase 2 - Bos taurus
(Bovine)
Length = 747
Score = 133 bits (322), Expect = 2e-29
Identities = 93/274 (33%), Positives = 134/274 (48%), Gaps = 18/274 (6%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER--EEFERDV 743
L + KL +G+FG V E D +G S VAVK L D + ++F R+V
Sbjct: 126 LHLFEKLGDGSFGVVRRGEWDAP---SGKTVS----VAVKCLKPDVLSQPEAMDDFIREV 178
Query: 744 RILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPP-TAATLLHIATQIAA 802
+ +L +L R+ G +PP+ +V E LG L LR TL A Q+A
Sbjct: 179 NAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAE 238
Query: 803 GMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWAA 861
GM YLE+ F+HRDLAARN L+ +KI DFG D+Y + +P W A
Sbjct: 239 GMGYLEAKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCA 298
Query: 862 WESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVD 921
ES+ ++ SD W F VTL E+++ + P+ L ++L + D E +
Sbjct: 299 PESLKTRTFSHASDTWMFGVTLWEMFTY-GQEPWIGLNGSQILHKI------DKEGERLP 351
Query: 922 RAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
R CP+D+Y +M++CW DRPTF + FL
Sbjct: 352 RPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL 385
>UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1;
Sycon raphanus|Rep: Tyrosine-protein kinase receptor -
Sycon raphanus
Length = 616
Score = 133 bits (321), Expect = 3e-29
Identities = 97/290 (33%), Positives = 147/290 (50%), Gaps = 37/290 (12%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
L MI ++ EGAFG VY V + G +T VA+K L T+ +R F + I
Sbjct: 217 LTMIREVGEGAFGKVYEGLLATVED--GDMT-----VAIKTLSVCDTMGQRNAFLAEASI 269
Query: 746 LAALSSPHLARVLG--ACRSPPLAVVLEYLELGDLCAFLRAAIP---------------- 787
+ SP++ R++G + + PL VV+E++ GDL ++R P
Sbjct: 270 MKKFDSPYVMRLMGLVSTENKPL-VVMEFMAEGDLRGYVRKCRPQNRQFSINSIETNGSA 328
Query: 788 ------PTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEA 841
PTA + A Q++ GM Y+ +FVHRDLAARNC++ +KI DFG +
Sbjct: 329 ASVYGIPTAERFMLWALQLSKGMAYVHEKHFVHRDLAARNCMLSSNLTLKIGDFGFTRDI 388
Query: 842 YTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
Y DYY+ G+ LP+RW E++ G Y +SDVW++ V L E+ +L +PY+ ++
Sbjct: 389 YESDYYRKTGKGALPVRWMGPEALRDGMYIPESDVWSYGVVLWEMATL-GDQPYKGKSNE 447
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
EV +S + A D M P+ +LM CW+ +RPTF +I
Sbjct: 448 EV---ISLVIAGDHM-PLPITLHDFPQPCLDLMETCWQFQPAERPTFEKI 493
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 133 bits (321), Expect = 3e-29
Identities = 91/282 (32%), Positives = 143/282 (50%), Gaps = 28/282 (9%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E PR++L + KL +G FG V+ + G+ E VA+K + T+ E F
Sbjct: 256 EIPRNQLHLKRKLGDGNFGEVWYGKWRGIVE-----------VAIKTM-KPGTMSP-EAF 302
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAIPPTAA-TLLHIA 797
++ +I+ P+L ++ C R P ++ EY+ G L +LR L+ +A
Sbjct: 303 LQEAQIMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMA 362
Query: 798 TQIAAGMQYLESLNFVHRDLAARNCLIGKGYQ----IKISDFGTDNEAYTCDYYKVDGRV 853
QIA GM YLE VHRDLAARN L+G +K++DFG + D Y+
Sbjct: 363 AQIANGMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKLMEEDIYEARTGA 422
Query: 854 PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQAD 913
P++W A E+ G +T KSDVW++ + L+EI + + PY + + EV++ Q +
Sbjct: 423 KFPIKWTAPEAATCGNFTVKSDVWSYGILLYEIMTK-GQVPYPGMHNREVVE-----QVE 476
Query: 914 DGMFECVDRAPGCPRDLY-ELMLECWRRDELDRPTFGEIHLF 954
G + R GCP +Y E++L+CW + RPTF ++ F
Sbjct: 477 LGYRMPMPR--GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHF 516
>UniRef50_A7SE14 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 311
Score = 133 bits (321), Expect = 3e-29
Identities = 98/294 (33%), Positives = 148/294 (50%), Gaps = 33/294 (11%)
Query: 682 PRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFER 741
PR R+ ++ + GAFG V+ G+ G + LVA+K DA+ E + +
Sbjct: 8 PRERIHIMKVIGNGAFGQVHKGRVHGL----GTNSPGWTLVAIKSPYADASDAETRDLMK 63
Query: 742 DVRILAALSS-PHLARVLGACRSP--PLAVVLEYLELGDLCAFLRAA------------I 786
+ +L L S PH+ ++LG PL V++EY+ GDL +LR + I
Sbjct: 64 EFELLKRLKSHPHVIKLLGCGEDDGRPL-VIIEYVPHGDLLGYLRKSRGEEDSYYPDPEI 122
Query: 787 PP----TAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAY 842
P ++ L+ A Q+A GMQYL S +HRDLAARN L+G+G K++DFG +
Sbjct: 123 KPKTSLSSQQLVRFAWQVADGMQYLSSQKIIHRDLAARNILVGEGEVCKVTDFGMAKDVQ 182
Query: 843 TCDYYKVDGRVPLPLRWAAWESVL-RGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDC 901
D Y LP++W A E+++ G+YTT+SDVW+F V L+EI ++ PY +
Sbjct: 183 NEDIYIRTTEGRLPVKWTAIEALIGGGEYTTQSDVWSFGVVLYEICTI-GGEPYPGIAGK 241
Query: 902 EVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
++ + +L+A M C LYE+M CW RPTF + L
Sbjct: 242 DIPE---YLEAGYRM-SCPTHLDA---TLYEIMASCWATCPDMRPTFTSLEKLL 288
>UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack
CG14992-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Ack CG14992-PA - Apis mellifera
Length = 1302
Score = 132 bits (320), Expect = 3e-29
Identities = 86/242 (35%), Positives = 119/242 (49%), Gaps = 9/242 (3%)
Query: 716 TSEKRLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLEL 775
+ K VAVK L DA E F +V+++ L +L R+ G S P+ +V E L
Sbjct: 133 SGRKLPVAVKVLKADAQPSVIENFVSEVQVMHTLDHQNLIRLYGVVLSQPMMMVTELASL 192
Query: 776 GDLCAFLRAAIPPTAA-TLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISD 834
G L +LR + TL A Q+A GM YLE+ F+HRDLA RN L+ ++KI D
Sbjct: 193 GALLDYLRKQCGQISVLTLCDYALQVATGMAYLEAKRFLHRDLACRNVLLSSIDKVKIGD 252
Query: 835 FGTDNE-AYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR 893
FG D Y + +P W A ES+ R K+T SDVW F VTL E+ +
Sbjct: 253 FGLMRALPQQEDCYVMSEHKKVPFPWCAPESLKRRKFTHASDVWMFGVTLWEMLTF-GEE 311
Query: 894 PYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHL 953
P+ L E+L + D E + P ++Y+LML CW D +RPTF + +
Sbjct: 312 PWVGLKGSEILRKI------DKEGERLHEPEATPPEMYQLMLRCWACDPSERPTFASLRV 365
Query: 954 FL 955
L
Sbjct: 366 SL 367
>UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep:
CG14992-PA - Drosophila melanogaster (Fruit fly)
Length = 1073
Score = 132 bits (320), Expect = 3e-29
Identities = 91/273 (33%), Positives = 134/273 (49%), Gaps = 17/273 (6%)
Query: 691 KLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKER--EEFERDVRILAA 748
KL +G+FG V E P G + VAVK L D + ++F R+V+ + A
Sbjct: 128 KLGDGSFGVVRRGEWSASPA--GKVIP----VAVKVLKSDNLTQPGIIDDFFREVQAMHA 181
Query: 749 LSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAATLL-HIATQIAAGMQYL 807
L +L R+ G S P+ ++ E E G L LR T+ T++ + + QI GM YL
Sbjct: 182 LDHANLVRLYGVVLSQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYL 241
Query: 808 ESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRVPLPLRWAAWESVL 866
E F+HRDLA RN L+ G +IKI DFG D Y + +P W A ES+
Sbjct: 242 EQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLR 301
Query: 867 RGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGC 926
+++ SD W F VTL E++S P+ L ++L + D E + + C
Sbjct: 302 FRQFSHASDTWMFGVTLWEMFSF-GEDPWVGLNGSQILRKI------DREGERLHQPDAC 354
Query: 927 PRDLYELMLECWRRDELDRPTFGEIHLFLQRKS 959
P D+Y +ML+CW + +RPTF + +L S
Sbjct: 355 PPDVYAMMLQCWDKTPAERPTFAALKEYLASMS 387
>UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin
receptor - Ciona intestinalis (Transparent sea squirt)
Length = 1006
Score = 132 bits (320), Expect = 3e-29
Identities = 83/247 (33%), Positives = 129/247 (52%), Gaps = 20/247 (8%)
Query: 720 RLVAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDL 778
+ VA+K L +ER +F + I+ P++ R+ G +S PL ++ E++E G L
Sbjct: 668 KCVAIKTLKVGYNTQERSDFLGEASIMGQFDHPNVIRLEGVVTKSRPLMIITEFMENGSL 727
Query: 779 CAFLR---AAIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDF 835
AFLR IP +A L + IA GM+YL ++ +VHRDLAARN L+ K+SDF
Sbjct: 728 DAFLRNQEGKIP--SAQLTEMLLSIAQGMEYLSNMGYVHRDLAARNILVNSNLVCKVSDF 785
Query: 836 GTDN-----EAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLC 890
G E Y G + +P+RW + E++ ++T SDVW+F + + E+ S
Sbjct: 786 GLSRVLEQLEEDDVAMYTTRGGM-IPIRWTSPEAITMRTFSTSSDVWSFGIVMWEVMSF- 843
Query: 891 RRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGE 950
RPY +++ +V+ + D G + CPR ++ +MLECW+RD RP F
Sbjct: 844 GERPYWEMSNQDVVQFV-----DSGY--RLPPPCYCPRIIHSVMLECWKRDRTQRPNFSH 896
Query: 951 IHLFLQR 957
+ L R
Sbjct: 897 LVTLLDR 903
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 132 bits (319), Expect = 4e-29
Identities = 84/274 (30%), Positives = 142/274 (51%), Gaps = 24/274 (8%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E +L I +L G FG V + G + VA+K + + ++ E ++F
Sbjct: 331 EIDPRQLTFIRELGNGQFGVVKYGKWQG-----------RHDVAIKMV-KEGSMSE-DDF 377
Query: 740 ERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCAFLRAAI-PPTAATLLHIA 797
+ +++ L +L ++ G C + P+ +V EYL G L +L+ + PT+ LL +
Sbjct: 378 IEEAKVMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQEGLLNPTSIALLEMC 437
Query: 798 TQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPL 857
++ GM+YLE+ F+HRDLAARNCL+ IK++DFG +Y G P+
Sbjct: 438 KDVSEGMKYLEANQFIHRDLAARNCLVDSNGTIKVTDFGLSRYVLDDEYTSSVGS-KFPV 496
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
RW+ E +L K+++KSD+WAF V + EIY+ R PY+ + E+++ +S A ++
Sbjct: 497 RWSPPEVLLYCKFSSKSDIWAFGVLMWEIYTQ-GRMPYDRWNNTEIVEKIS---AGHRLY 552
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
R +++ +M CW +RPTF E+
Sbjct: 553 ----RPQMANENVFAIMNSCWHERPDERPTFQEL 582
>UniRef50_UPI0000F1D883 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1162
Score = 132 bits (319), Expect = 4e-29
Identities = 92/286 (32%), Positives = 147/286 (51%), Gaps = 25/286 (8%)
Query: 683 RHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERD 742
RH L I ++ G FG V + E + G T++ V VK L A+++E+ +F +
Sbjct: 14 RHSLLYIKEMGHGWFGKVLLGEVNA-----GLSTTQ---VVVKELKASASVQEQMQFLEE 65
Query: 743 VRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRA-----AIPPTAATLLHI 796
V+ L P L + L + P +V+E+ LGD+ +LR+ ++ P L +
Sbjct: 66 VQPYRVLQHPALLQCLSQSTEVTPYLLVMEHCPLGDVKGYLRSCRAADSVTPDPLILQRM 125
Query: 797 ATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLP 856
A +IA+G+ YL N++H DLA RNCL+ +KI D+G + Y DYY ++ +P
Sbjct: 126 ACEIASGLLYLHKHNYIHSDLALRNCLLTSELAVKIGDYGLSHSKYKDDYYVTADQIWVP 185
Query: 857 LRWAAWE-------SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSH 909
LRW A E ++L T S+VW+ VT+ E++ L +PY H +D +VL +
Sbjct: 186 LRWIAPELIDEVHGNLLVVDQTKASNVWSLGVTIWELFEL-GNQPYRHYSDRQVL-TYAV 243
Query: 910 LQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+ + + + + P C R YE+M CW + E RP E+HL L
Sbjct: 244 KEQQLKLPKPLLKVPLCER-WYEVMQFCWLQPE-QRPVVEEVHLLL 287
>UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona
intestinalis|Rep: Receptor tyrosine kinase X - Ciona
intestinalis (Transparent sea squirt)
Length = 478
Score = 132 bits (319), Expect = 4e-29
Identities = 93/285 (32%), Positives = 145/285 (50%), Gaps = 20/285 (7%)
Query: 673 LETTNVIEFPRHRLRMISK---LAEGAFGTVYVAE--ADGVPEYNGAITSEKRLVAVKFL 727
L+ + + R++L M+ K + +G FGTVY E + + NG KR VA+K L
Sbjct: 129 LQEMSSVLISRNKL-MVDKENIIGKGHFGTVYNGEYITSEISKLNG--NPIKRKVAIKTL 185
Query: 728 CHDATLKEREEFERDVRILAALSSPHLARVLGACRSPPLA--VVLEYLELGDLCAFLRA- 784
+ E+F ++ +++ ++ ++G A VVL Y+ GDL F+R
Sbjct: 186 SKIEDTESVEKFLKEGLMMSDFHDENVLTLIGISWDDDGAPMVVLPYMMHGDLLQFIRKP 245
Query: 785 AIPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTC 844
+ PT L+ Q GM YL S FVHRDLAARNC++ + Y +K++DFG + Y
Sbjct: 246 SNNPTVKDLVGFGLQACKGMCYLASQRFVHRDLAARNCMLNETYVVKVADFGLARDIYEK 305
Query: 845 DYYKVDGRV-PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
+YYK +P++W A ES+ + +T K+DVW+F + L E+ + R D +
Sbjct: 306 EYYKPHEHAGRMPVKWMALESLQQQTFTIKTDVWSFGILLWELLT----RGVTPYPDVDA 361
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
D ++++ DG + + CP LYELML CW RP F
Sbjct: 362 FDVVNYIL--DG--RRLRQPQYCPDPLYELMLSCWHPLPETRPDF 402
>UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;
n=6; Bilateria|Rep: Developmental receptor tyrosine
kinase - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 874
Score = 132 bits (318), Expect = 6e-29
Identities = 97/295 (32%), Positives = 150/295 (50%), Gaps = 32/295 (10%)
Query: 668 DLKRRLETTNVIEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFL 727
DLK +L+ +V+ F R L + L +G FG+V EA E N + VAVK L
Sbjct: 482 DLKAKLQ--DVLIFER-LLTLGRMLGKGEFGSV--REAFLKSENNSG-----QKVAVKVL 531
Query: 728 CHDA-TLKEREEFERDVRILAALSSPHLARVLGAC-------RSPPLAVVLEYLELGDLC 779
D + + E+ ++ + P++ +++G R P V+L +++ GDL
Sbjct: 532 KTDINSSSDIEQCLKEAAYMKDFHHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLH 591
Query: 780 AFL---RAAIPPTAAT---LLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKIS 833
FL R P + L+ IA GM+YL + N +HRDLAARNC++ + + ++
Sbjct: 592 TFLLMSRLGDEPFTVSQQILIQFMLDIARGMEYLSNKNIIHRDLAARNCMLNENMSVCVA 651
Query: 834 DFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRR 893
DFG + Y+ DYY+ LP++W A ES+ YTT+SDVWAF VT+ EI + +
Sbjct: 652 DFGLSKKIYSGDYYRQGSVSKLPVKWIALESLADNVYTTQSDVWAFGVTMWEIMTR-GQT 710
Query: 894 PYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
PY + + E+ + L E + + P CP D+YE+M CW RP+F
Sbjct: 711 PYPGVENSEIYEYLI-------KGERLKQPPDCPADIYEIMHSCWSPVPKCRPSF 758
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 132 bits (318), Expect = 6e-29
Identities = 77/222 (34%), Positives = 115/222 (51%), Gaps = 11/222 (4%)
Query: 737 EEFERDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLR--AAIPPTAATLL 794
+ F + ++ L L R+ P+ ++ EY+E G L FL+ + I T LL
Sbjct: 290 DAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLL 349
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
+A QIA GM ++E N++HRDL A N L+ KI+DFG +Y +G
Sbjct: 350 DMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREG-AK 408
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
P++W A E++ G +T KSDVW+F + L EI + R PY +T+ EV+ NL +
Sbjct: 409 FPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVT-HGRIPYPGMTNPEVIQNL------E 461
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ V R CP +LY+LM CW+ DRPTF + L+
Sbjct: 462 RGYRMV-RPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 502
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 131 bits (317), Expect = 8e-29
Identities = 88/278 (31%), Positives = 139/278 (50%), Gaps = 26/278 (9%)
Query: 682 PRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFER 741
P+ L S + +G FG V++ + +G K++ H K + +F
Sbjct: 222 PKASLLKKSLIGKGEFGEVWLGDYEG-----------KKVAMKSMKDHLKDEKAKTQFLA 270
Query: 742 DVRILAALSSPHLARVLG-ACRSPPLAVVLEYLELGDLCAFLRAA--IPPTAATLLHIAT 798
+ ++ L P+L ++G + P+ ++ E++ G L +LR+ T + A
Sbjct: 271 EASVMTTLRHPNLVCLIGISLDDNPIYLITEFMAKGSLIDYLRSRGRAVITKQNQIDFAR 330
Query: 799 QIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLR 858
+ GM YLES NFVHRDLAARN LI + K+SDFG A + K +G LP++
Sbjct: 331 DVVKGMVYLESQNFVHRDLAARNVLIAEDNVAKVSDFGL---AKSSSNVKQEG-AKLPVK 386
Query: 859 WAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFE 918
W A E++ K++ K+DVW+F V L EIYS R PY + V D +H++ M
Sbjct: 387 WTAPEALRENKFSNKTDVWSFGVLLWEIYSY-GRVPYPRV---PVEDVANHVENGYRM-- 440
Query: 919 CVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQ 956
+ GCP +Y++M++CW +D RP F I L+
Sbjct: 441 --ESPDGCPDQIYKIMMDCWEKDPSQRPNFTRIEKALE 476
>UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep:
CG1511-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1096
Score = 131 bits (317), Expect = 8e-29
Identities = 82/233 (35%), Positives = 124/233 (53%), Gaps = 12/233 (5%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L ++ K R +F + I+ P++ + G RS P+ ++ EY+E G L
Sbjct: 772 VAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDT 831
Query: 781 FLRAAIPPTAATLLHIATQ-IAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN 839
FLR L + + IA+GM YL +N+VHRDLAARN L+ KI+DFG
Sbjct: 832 FLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSR 891
Query: 840 EAYTC-DYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHL 898
E D Y G +P+RW A E++ K+T+ SDVW++ V L E+ S RPY +
Sbjct: 892 EIENASDAYTTRGG-KIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSY-GERPYWNW 949
Query: 899 TDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
++ +V+ ++ + G + CP LY+LML+CW++ RPTF I
Sbjct: 950 SNQDVIKSI-----EKGY--RLPAPMDCPEALYQLMLDCWQKQRTHRPTFASI 995
>UniRef50_A7RGV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 250
Score = 131 bits (317), Expect = 8e-29
Identities = 88/223 (39%), Positives = 122/223 (54%), Gaps = 25/223 (11%)
Query: 752 PHLARVLGACR-SPPLAVVLEYLELGDLCAFL---RAAIPPTAAT-------------LL 794
P++ ++GAC PL VV+E++E GDL L R + A++ LL
Sbjct: 15 PNVVSLVGACTLDEPLFVVIEFVEGGDLRDLLLKSRMSRNKWASSSYENLRSRLNERQLL 74
Query: 795 HIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVP 854
+A +A GM +LE +HRDLAARN L+G G K++DFG T Y V +
Sbjct: 75 FLALGVARGMAHLEEKQCIHRDLAARNVLVGLGLVAKVADFGLARHVTTDGLYIVSAQTK 134
Query: 855 LPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADD 914
LP +W A ES LRG YTTKSDVW+F V L EI +L PY + + ++ L HL D
Sbjct: 135 LPWKWMAPES-LRGLYTTKSDVWSFGVVLWEIATL-GETPYPN--EVSIMKLLQHL--ID 188
Query: 915 GMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFLQR 957
G + + P C ++Y+LMLECW+ D RP+F EI L++
Sbjct: 189 G--HRMSKPPYCDEEIYKLMLECWQLDPATRPSFKEIERTLKK 229
>UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle
specific tyrosine kinase receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
muscle specific tyrosine kinase receptor -
Strongylocentrotus purpuratus
Length = 827
Score = 131 bits (316), Expect = 1e-28
Identities = 93/288 (32%), Positives = 146/288 (50%), Gaps = 28/288 (9%)
Query: 679 IEFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREE 738
+E+ R+ + + EGAFG V++A A + A TS VAVK L A E
Sbjct: 532 LEYNRNNVIYEKDIGEGAFGRVFMASAPKLVA-GEAETS----VAVKMLKATADKVVTEY 586
Query: 739 FERDVRILAALSSPHLARVLGACR-SPPLAVVLEYLELGDLCAFLRAAIPPTAATL---- 793
F R+ +++A S ++ ++LG C PL ++LEY+ GDL +L + P + +
Sbjct: 587 FNREAQMIARFSHQNIVKLLGVCFVGRPLCLLLEYMSEGDLEDYLHSRSPHRSNSRTSNS 646
Query: 794 ----------LHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
L++A QIA GM YL + FVHRD+A RNCLI +KISDFG
Sbjct: 647 PGSGLKTYEKLNMAKQIACGMAYLNEMMFVHRDIATRNCLINSRTDVKISDFGLARYVGH 706
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
+ + +P+RW A E++ ++T SDVW+F V L E++S +PY +L+ +V
Sbjct: 707 KECFVGHKEEHIPIRWTAPEALWDYQFTYASDVWSFGVLLWELFSYA-EQPYLNLSHEDV 765
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
L G + P+ ++++M ECW+ + DRP F ++
Sbjct: 766 F-----LHTRQGY--RLSSLENTPQKVHQIMGECWQANPADRPFFKQL 806
>UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1042
Score = 131 bits (316), Expect = 1e-28
Identities = 82/242 (33%), Positives = 131/242 (54%), Gaps = 17/242 (7%)
Query: 722 VAVKFLCHDATLKEREEFERDVRILAALSSPHLARVLGAC-RSPPLAVVLEYLELGDLCA 780
VA+K L + K+R +F + I+ S P++ + G + + +V EY++ G L
Sbjct: 711 VAIKTLKPGYSEKQRLDFLSEASIMGQFSHPNIIHLEGVVTKFKHIMIVTEYMDNGALDT 770
Query: 781 FLRAA---IPPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
+L+ IPP L+ + IAAGMQYL ++++VHRDLAARN L+ + K+SDFG
Sbjct: 771 YLKGRDGEIPPYQ--LVGMLRGIAAGMQYLSNMSYVHRDLAARNILVNSNLECKVSDFGL 828
Query: 838 DNEAYTCD--YYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPY 895
D Y G +P+RW A E++ K+T+ SDVW+F + + E+ + RPY
Sbjct: 829 SRVLEDDDEGTYTTRGG-KIPIRWTAPEAIAYRKFTSASDVWSFGIVMWEVMAF-GERPY 886
Query: 896 EHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEIHLFL 955
+++ EV ++A + F + CP +Y+LML+CW+ D RP F +I FL
Sbjct: 887 WDMSNHEV------MKAINEAFR-LPAPMDCPSAIYQLMLQCWQHDRSKRPRFSDIVSFL 939
Query: 956 QR 957
+
Sbjct: 940 DK 941
>UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora|Rep:
CG14396-PD, isoform D - Drosophila melanogaster (Fruit
fly)
Length = 1237
Score = 131 bits (316), Expect = 1e-28
Identities = 98/285 (34%), Positives = 136/285 (47%), Gaps = 30/285 (10%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
EFPR +L++ + L EG FG V A + G T VAVK L + E
Sbjct: 767 EFPREKLQLDTVLGEGEFGQVLKGFATEIAGLPGITT-----VAVKMLKKGSNSVEYMAL 821
Query: 740 ERDVRILAALSSPHLARVLGACRSP--PLAVVLEYLELGDLCAFLR-------AAI---- 786
+ ++L +S P++ ++LGAC S PL +++EY G L ++LR A +
Sbjct: 822 LSEFQLLQEVSHPNVIKLLGACTSSEAPL-LIIEYARYGSLRSYLRLSRKIECAGVDFAD 880
Query: 787 ---PPTAATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYT 843
P +L A QI GM YL L VHRDLAARN L+ G KISDFG + Y
Sbjct: 881 GVEPVNVKMVLTFAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYE 940
Query: 844 CDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEV 903
D Y R +P++W A ES+ YT+KSDVW+F V E+ +L PY +
Sbjct: 941 DDAYLKRSRDRVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITL-GASPYPGIAP--- 996
Query: 904 LDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTF 948
NL L +DR C +Y ++ CW + RP+F
Sbjct: 997 -QNLWSLLKTGYR---MDRPENCSEAVYSIVRTCWADEPNGRPSF 1037
>UniRef50_Q674V1 Cluster: Vascular endothelial growth factor receptor;
n=1; Podocoryne carnea|Rep: Vascular endothelial growth
factor receptor - Podocoryne carnea
Length = 1254
Score = 130 bits (315), Expect = 1e-28
Identities = 89/257 (34%), Positives = 136/257 (52%), Gaps = 27/257 (10%)
Query: 715 ITS-EKRLVAVKFLCHDATLKEREEFERDVRILAALSS-PHLARVLGACRSP-PLAVVLE 771
+TS EK +VAVK L DA E ++ +++IL L ++ +LGAC + L V+LE
Sbjct: 887 VTSLEKSMVAVKTLKDDAAEGEYKDLASELKILIHLGEHKNIVNLLGACTTNGKLYVILE 946
Query: 772 YLELGDLCAFLRA---AIPP-------------TAATLLHIATQIAAGMQYLESLNFVHR 815
G+L FLR P T LL I Q+A M +L+S VHR
Sbjct: 947 CCPRGNLLTFLRGKRETFQPVWTKYDTDMENEFTYIDLLMIVIQVAKRMDFLQSQKCVHR 1006
Query: 816 DLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSD 875
DLAARN L+G Y +KI+DFG + Y ++Y + LP++W A ES+ YT+ SD
Sbjct: 1007 DLAARNVLVGPDYIMKIADFGLARDIYKDEFYLKETTGLLPVKWMAPESLFDKVYTSMSD 1066
Query: 876 VWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELML 935
+W++ + L E ++L PY L ++ L +DG + ++R CP+ ++E+M
Sbjct: 1067 IWSYGIVLWEAFTL-GGSPYPGLPTEDLFGFL-----EDG--KRMERPEICPKSVFEIMS 1118
Query: 936 ECWRRDELDRPTFGEIH 952
+CW + DRP F +I+
Sbjct: 1119 DCWTKSPYDRPMFSQIY 1135
Score = 38.7 bits (86), Expect = 0.75
Identities = 15/29 (51%), Positives = 22/29 (75%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGV 708
EFPR ++ +I L GAFG V++AEA+G+
Sbjct: 816 EFPRSKISLIKTLGSGAFGQVWLAEAEGI 844
>UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 315
Score = 130 bits (315), Expect = 1e-28
Identities = 98/294 (33%), Positives = 148/294 (50%), Gaps = 36/294 (12%)
Query: 680 EFPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEF 739
E P L +I +L G FG V A A G+P + G +T VAVK L A K++ +F
Sbjct: 22 EVPPQNLSVIKRLGSGNFGHVDKAMAIGIPGFPGQVT-----VAVKTLKATAQEKDKTDF 76
Query: 740 ERDVRILAALSS-PHLARVLGACR------SPPLAVVLEYLELGDLCAFLRAAI------ 786
++ ++ +L PH+ R++G C S LA++ EYL GDL +LR +
Sbjct: 77 LTELNLMKSLRPHPHVVRLIGCCTRQAGELSNHLAIIFEYLPYGDLLGYLRRSRGHEDWY 136
Query: 787 ------PPT---AATLLHIATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGT 837
PP+ + L+ A IA GM +L + VHRDLAARN L+G+ KISD G
Sbjct: 137 CSGDLRPPSRLVSKDLVKFAWMIADGMAFLAANKCVHRDLAARNVLVGEHNTCKISDLGL 196
Query: 838 DNEAYTCDYYKVDGRVPLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEH 897
+ + D Y LP++W ES+L G+ ++ SDVW++ + L EI+++ PY
Sbjct: 197 ARDV-SQDIYTRTSSARLPVKWMPPESLLYGQSSSASDVWSYGIVLWEIFTI-GDSPYPG 254
Query: 898 LTDCEVLDNLSHLQADDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
+ + L +G + + P LY +ML CW+ D +RPTF E+
Sbjct: 255 VKSKGIPRMLR-----EGY--RMPKPPHVGDALYFVMLRCWQEDPDERPTFDEL 301
>UniRef50_P21860 Cluster: Receptor tyrosine-protein kinase erbB-3
precursor; n=41; cellular organisms|Rep: Receptor
tyrosine-protein kinase erbB-3 precursor - Homo sapiens
(Human)
Length = 1342
Score = 130 bits (315), Expect = 1e-28
Identities = 93/274 (33%), Positives = 137/274 (50%), Gaps = 19/274 (6%)
Query: 681 FPRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFE 740
F LR + L G FGTV+ + +PE S K V +K + + + +
Sbjct: 704 FKETELRKLKVLGSGVFGTVH--KGVWIPEGE----SIKIPVCIKVIEDKSGRQSFQAVT 757
Query: 741 RDVRILAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLR---AAIPPTAATLLHIA 797
+ + +L H+ R+LG C L +V +YL LG L +R A+ P LL+
Sbjct: 758 DHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQL--LLNWG 815
Query: 798 TQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNEAYTCDYYKVDGRVPLPL 857
QIA GM YLE VHR+LAARN L+ Q++++DFG + D + P+
Sbjct: 816 VQIAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPI 875
Query: 858 RWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMF 917
+W A ES+ GKYT +SDVW++ VT+ E+ + PY L EV D L + G
Sbjct: 876 KWMALESIHFGKYTHQSDVWSYGVTVWELMTF-GAEPYAGLRLAEVPDLL-----EKG-- 927
Query: 918 ECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
E + + C D+Y +M++CW DE RPTF E+
Sbjct: 928 ERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL 961
>UniRef50_P04412 Cluster: Epidermal growth factor receptor precursor;
n=129; Endopterygota|Rep: Epidermal growth factor
receptor precursor - Drosophila melanogaster (Fruit fly)
Length = 1426
Score = 130 bits (315), Expect = 1e-28
Identities = 91/268 (33%), Positives = 140/268 (52%), Gaps = 17/268 (6%)
Query: 686 LRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFERDVRI 745
LR L GAFG VY + VPE K VA+K L + EEF R+ I
Sbjct: 938 LRKGGVLGMGAFGRVY--KGVWVPEGENV----KIPVAIKELLKSTGAESSEEFLREAYI 991
Query: 746 LAALSSPHLARVLGACRSPPLAVVLEYLELGDLCAFLRAAIPPTAA-TLLHIATQIAAGM 804
+A+ +L ++L C S + ++ + + LG L ++R + LL+ +TQIA GM
Sbjct: 992 MASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGM 1051
Query: 805 QYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDN-EAYTCDYYKVDGRVPLPLRWAAWE 863
YLE VHRDLAARN L+ +KI+DFG + + YK G +P++W A E
Sbjct: 1052 SYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGG-KMPIKWLALE 1110
Query: 864 SVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQADDGMFECVDRA 923
+ +T+KSDVWAF VT+ E+ + +RP+E++ ++ D + + G+ +++
Sbjct: 1111 CIRNRVFTSKSDVWAFGVTIWELLTF-GQRPHENIPAKDIPDLI-----EVGL--KLEQP 1162
Query: 924 PGCPRDLYELMLECWRRDELDRPTFGEI 951
C D+Y +L CW D RPTF ++
Sbjct: 1163 EICSLDIYCTLLSCWHLDAAMRPTFKQL 1190
>UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to
tyrosine-protein kinase pr2; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to tyrosine-protein
kinase pr2 - Nasonia vitripennis
Length = 1345
Score = 130 bits (314), Expect = 2e-28
Identities = 93/279 (33%), Positives = 142/279 (50%), Gaps = 25/279 (8%)
Query: 682 PRHRLRMISKLAEGAFGTVYVAEADGVPEYNGAITSEKRLVAVKFLCHDATLKEREEFER 741
P + + +L G FG V GV +G E+ VA+K L + EF +
Sbjct: 170 PADAIIVNKELGTGEFGVVQ----QGVWTNDG----ERIQVAIKCLSRERMQNNPIEFLK 221
Query: 742 DVRILAALSSPHLARVLGACRSP-PLAVVLEYLELGDL--CA---FLRAAIPPTAATLLH 795
+ I+ ++ H+ R+ G L +V E L L C LRA+ P +L
Sbjct: 222 EAAIMHSIDHEHIVRLYGVVLDTNSLMLVTELAPLRSLLECLKEPSLRASFP--VPSLCD 279
Query: 796 IATQIAAGMQYLESLNFVHRDLAARNCLIGKGYQIKISDFGTDNE-AYTCDYYKVDGRV- 853
+ QIA GMQYLE+ +HRDLAARN L+ ++KISDFG DYY+ + V
Sbjct: 280 FSVQIADGMQYLEAKRLIHRDLAARNILVFSKNKVKISDFGLSRALGVGKDYYQTNFNVN 339
Query: 854 -PLPLRWAAWESVLRGKYTTKSDVWAFAVTLHEIYSLCRRRPYEHLTDCEVLDNLSHLQA 912
LP+ W A E + K+T+ SDVWA+ VTL E++S +P+ LT ++L+ +
Sbjct: 340 LKLPIAWCAPECISYLKFTSASDVWAYGVTLWEMFSY-GFQPWAALTGHQILEAI----- 393
Query: 913 DDGMFECVDRAPGCPRDLYELMLECWRRDELDRPTFGEI 951
D+ F+ +++ CP+D + LM +CW+ + RP F E+
Sbjct: 394 DEPNFQRLEQPDCCPKDYFSLMQQCWQHEPTKRPKFSEL 432
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.135 0.414
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,124,238,018
Number of Sequences: 1657284
Number of extensions: 49388590
Number of successful extensions: 120503
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2975
Number of HSP's successfully gapped in prelim test: 4975
Number of HSP's that attempted gapping in prelim test: 108430
Number of HSP's gapped (non-prelim): 10949
length of query: 965
length of database: 575,637,011
effective HSP length: 108
effective length of query: 857
effective length of database: 396,650,339
effective search space: 339929340523
effective search space used: 339929340523
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 77 (35.1 bits)
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