SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000579-TA|BGIBMGA000579-PA|IPR001194|DENN,
IPR005112|dDENN
         (386 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI000051A218 Cluster: PREDICTED: similar to CG18659-PA...   358   1e-97
UniRef50_UPI0000D576CF Cluster: PREDICTED: similar to CG18659-PA...   355   1e-96
UniRef50_UPI00015B4183 Cluster: PREDICTED: similar to GA15037-PA...   338   1e-91
UniRef50_Q8TEH3 Cluster: DENN domain-containing protein 1A; n=51...   284   2e-75
UniRef50_A1Z7Q5 Cluster: CG18659-PA, isoform A; n=3; Sophophora|...   268   2e-70
UniRef50_Q6P3S1 Cluster: DENN domain-containing protein 1B; n=33...   252   1e-65
UniRef50_Q8IV53 Cluster: DENN domain-containing protein 1C; n=12...   248   3e-64
UniRef50_Q6DCI3 Cluster: LOC446246 protein; n=2; Xenopus|Rep: LO...   245   2e-63
UniRef50_Q8CFK6 Cluster: DENN domain-containing protein 1C; n=6;...   238   2e-61
UniRef50_Q4TJ11 Cluster: Chromosome undetermined SCAF1129, whole...   227   5e-58
UniRef50_UPI000056B3F1 Cluster: UPI000056B3F1 related cluster; n...   201   3e-50
UniRef50_Q20473 Cluster: Putative uncharacterized protein; n=3; ...   192   1e-47
UniRef50_Q4RJA5 Cluster: Chromosome 18 SCAF15038, whole genome s...   126   1e-27
UniRef50_Q59I62 Cluster: Fc11b09; n=9; Euteleostomi|Rep: Fc11b09...   118   2e-25
UniRef50_P78524 Cluster: Suppression of tumorigenicity 5; n=36; ...   117   6e-25
UniRef50_Q68D51 Cluster: DENN domain-containing protein 2C; n=30...   115   2e-24
UniRef50_Q54JA6 Cluster: Putative uncharacterized protein; n=1; ...   108   2e-22
UniRef50_UPI0000F20EF1 Cluster: PREDICTED: hypothetical protein,...   107   4e-22
UniRef50_Q9ULE3 Cluster: DENN domain-containing protein 2A; n=24...   107   4e-22
UniRef50_Q00WT6 Cluster: RAS signaling inhibitor ST5; n=2; Ostre...   103   1e-20
UniRef50_Q5U3I4 Cluster: Zgc:103487; n=4; Danio rerio|Rep: Zgc:1...   101   3e-20
UniRef50_Q9H6A0 Cluster: DENN domain-containing protein 2D; n=29...    99   2e-19
UniRef50_UPI0000F1E8B0 Cluster: PREDICTED: hypothetical protein;...    92   2e-17
UniRef50_UPI0000D571A2 Cluster: PREDICTED: similar to suppressio...    89   1e-16
UniRef50_UPI00015B4FAB Cluster: PREDICTED: similar to myotubular...    85   2e-15
UniRef50_Q1L8F0 Cluster: Novel protein; n=6; Clupeocephala|Rep: ...    84   5e-15
UniRef50_UPI0000DB6D52 Cluster: PREDICTED: similar to SET domain...    83   9e-15
UniRef50_UPI00006A2097 Cluster: DENN domain-containing protein 1...    80   8e-14
UniRef50_Q6NZD6 Cluster: Dennd2c protein; n=4; Euteleostomi|Rep:...    78   3e-13
UniRef50_Q4S7I6 Cluster: Chromosome 13 SCAF14715, whole genome s...    77   1e-12
UniRef50_Q8BJD2 Cluster: 0 day neonate eyeball cDNA, RIKEN full-...    76   1e-12
UniRef50_UPI000049A2A5 Cluster: DENN domain protein; n=3; Entamo...    76   2e-12
UniRef50_A0DVL5 Cluster: Chromosome undetermined scaffold_66, wh...    76   2e-12
UniRef50_Q6IQ26 Cluster: Rab6-interacting protein 1; n=59; Eumet...    75   2e-12
UniRef50_Q54JL9 Cluster: Putative uncharacterized protein; n=1; ...    75   3e-12
UniRef50_UPI0000499496 Cluster: hypothetical protein 153.t00003;...    75   4e-12
UniRef50_A2G0S6 Cluster: Putative uncharacterized protein; n=1; ...    74   6e-12
UniRef50_Q55FT6 Cluster: Putative uncharacterized protein; n=1; ...    74   7e-12
UniRef50_UPI0000498ADA Cluster: conserved hypothetical protein; ...    72   2e-11
UniRef50_Q54VP0 Cluster: Putative uncharacterized protein; n=1; ...    72   3e-11
UniRef50_Q55DD7 Cluster: Putative uncharacterized protein; n=1; ...    71   5e-11
UniRef50_Q6NTN5 Cluster: Myotubularin-related protein 13; n=7; E...    71   5e-11
UniRef50_Q7PWX7 Cluster: ENSANGP00000020490; n=1; Anopheles gamb...    70   9e-11
UniRef50_A6PVG9 Cluster: SET binding factor 1; n=28; Euteleostom...    70   9e-11
UniRef50_O95248 Cluster: Myotubularin-related protein 5; n=55; D...    70   9e-11
UniRef50_UPI000049A4AE Cluster: hypothetical protein 675.t00001;...    69   2e-10
UniRef50_Q7Q9J0 Cluster: ENSANGP00000010428; n=1; Anopheles gamb...    69   2e-10
UniRef50_UPI000049911F Cluster: conserved hypothetical protein; ...    68   5e-10
UniRef50_UPI00015A64BC Cluster: DENN/MADD domain containing 3; n...    68   5e-10
UniRef50_Q9VGH9 Cluster: CG6939-PA, isoform A; n=2; Drosophila m...    68   5e-10
UniRef50_Q7KSP6 Cluster: CG6939-PB, isoform B; n=5; Diptera|Rep:...    68   5e-10
UniRef50_Q0IEN0 Cluster: Rab6-interacting; n=2; Culicidae|Rep: R...    68   5e-10
UniRef50_Q9W3D3 Cluster: CG12737-PA, isoform A; n=6; Sophophora|...    67   6e-10
UniRef50_Q8RXA7 Cluster: Stomatal cytokinesis defective; n=3; Ar...    67   8e-10
UniRef50_A7EF60 Cluster: Putative uncharacterized protein; n=3; ...    66   1e-09
UniRef50_O02626 Cluster: MAP kinase-activating death domain prot...    66   1e-09
UniRef50_Q6ZGD1 Cluster: DENN (AEX-3) domain-containing protein-...    66   1e-09
UniRef50_UPI0000DB72B4 Cluster: PREDICTED: similar to CG7852-PA,...    66   2e-09
UniRef50_Q10RU8 Cluster: DENN domain containing protein, express...    65   3e-09
UniRef50_Q9VXY2 Cluster: MAP kinase-activating death domain prot...    65   3e-09
UniRef50_UPI0000498ED2 Cluster: protein with DENN and LIM domain...    65   3e-09
UniRef50_Q01H37 Cluster: RAS signaling inhibitor ST5; n=4; cellu...    65   3e-09
UniRef50_UPI0000499578 Cluster: conserved hypothetical protein; ...    64   4e-09
UniRef50_UPI00006A08E0 Cluster: DENN domain-containing protein 1...    64   4e-09
UniRef50_A7RH02 Cluster: Predicted protein; n=1; Nematostella ve...    64   6e-09
UniRef50_A0C7E2 Cluster: Chromosome undetermined scaffold_155, w...    64   6e-09
UniRef50_UPI0000D556CB Cluster: PREDICTED: similar to CG12737-PB...    64   8e-09
UniRef50_O75064 Cluster: DENN domain-containing protein 4B; n=20...    64   8e-09
UniRef50_Q54GF5 Cluster: Putative uncharacterized protein; n=1; ...    63   1e-08
UniRef50_Q18780 Cluster: Putative uncharacterized protein; n=2; ...    63   1e-08
UniRef50_A7PDY4 Cluster: Chromosome chr11 scaffold_13, whole gen...    62   2e-08
UniRef50_Q9Y7Q7 Cluster: Diacylglycerol binding protein; n=1; Sc...    62   2e-08
UniRef50_Q0JLS4 Cluster: Os01g0575500 protein; n=5; Magnoliophyt...    62   3e-08
UniRef50_Q9P3C6 Cluster: Putative uncharacterized protein B13I18...    62   3e-08
UniRef50_UPI00006CD2CF Cluster: hypothetical protein TTHERM_0026...    61   4e-08
UniRef50_A1CGV5 Cluster: DDENN domain protein; n=10; Pezizomycot...    61   4e-08
UniRef50_UPI0000E48609 Cluster: PREDICTED: similar to RAB6 inter...    61   6e-08
UniRef50_UPI0000499224 Cluster: hypothetical protein 12.t00030; ...    60   7e-08
UniRef50_UPI0000498334 Cluster: DENN domain protein; n=1; Entamo...    60   1e-07
UniRef50_Q00T31 Cluster: DENN; n=2; Ostreococcus|Rep: DENN - Ost...    60   1e-07
UniRef50_A4HMW3 Cluster: Putative uncharacterized protein; n=3; ...    59   2e-07
UniRef50_UPI00006CFBF6 Cluster: DENN domain; n=1; Tetrahymena th...    58   3e-07
UniRef50_Q7PRP6 Cluster: ENSANGP00000001501; n=1; Anopheles gamb...    58   4e-07
UniRef50_Q4DVP9 Cluster: Putative uncharacterized protein; n=2; ...    58   4e-07
UniRef50_Q22KG2 Cluster: Putative uncharacterized protein; n=1; ...    58   4e-07
UniRef50_UPI0000F201E9 Cluster: PREDICTED: hypothetical protein,...    58   5e-07
UniRef50_A0PJS2 Cluster: LOC798528 protein; n=5; Euteleostomi|Re...    58   5e-07
UniRef50_UPI0000ECC1A9 Cluster: DENN domain-containing protein 4...    57   7e-07
UniRef50_A0D0B3 Cluster: Chromosome undetermined scaffold_33, wh...    57   7e-07
UniRef50_Q5VZ89 Cluster: DENN domain-containing protein 4C; n=23...    57   9e-07
UniRef50_UPI0000E254A2 Cluster: PREDICTED: similar to DENN/MADD ...    56   1e-06
UniRef50_UPI0000DB7B17 Cluster: PREDICTED: similar to Calmodulin...    56   1e-06
UniRef50_Q4SZS2 Cluster: Chromosome undetermined SCAF11526, whol...    56   1e-06
UniRef50_A2EIL7 Cluster: Putative uncharacterized protein; n=2; ...    56   1e-06
UniRef50_UPI0000499D60 Cluster: conserved hypothetical protein; ...    56   2e-06
UniRef50_Q9W0E1 Cluster: CG7852-PA, isoform A; n=3; Sophophora|R...    56   2e-06
UniRef50_A2RUS2 Cluster: DENN domain-containing protein 3; n=22;...    56   2e-06
UniRef50_UPI0000498BD5 Cluster: conserved hypothetical protein; ...    56   2e-06
UniRef50_UPI000065FFA3 Cluster: DENN/MADD domain containing 4B.;...    56   2e-06
UniRef50_UPI000065F171 Cluster: DENN domain-containing protein 4...    55   3e-06
UniRef50_O08873 Cluster: MAP kinase-activating death domain prot...    55   3e-06
UniRef50_A2AGQ3 Cluster: MAP-kinase activating death domain; n=2...    55   4e-06
UniRef50_UPI00006CBA46 Cluster: hypothetical protein TTHERM_0049...    54   5e-06
UniRef50_Q4SJ20 Cluster: Chromosome 21 SCAF14577, whole genome s...    54   5e-06
UniRef50_A7RR72 Cluster: Predicted protein; n=7; Eumetazoa|Rep: ...    54   5e-06
UniRef50_Q8WXG6 Cluster: MAP kinase-activating death domain prot...    54   5e-06
UniRef50_UPI00015A7BBA Cluster: MAP kinase-activating death doma...    54   6e-06
UniRef50_UPI00015A7BA8 Cluster: MAP kinase-activating death doma...    54   6e-06
UniRef50_Q4RI35 Cluster: Chromosome 8 SCAF15044, whole genome sh...    54   6e-06
UniRef50_Q4SHF6 Cluster: Chromosome 5 SCAF14581, whole genome sh...    53   1e-05
UniRef50_Q9TXV4 Cluster: Putative uncharacterized protein; n=2; ...    53   1e-05
UniRef50_UPI0000F20348 Cluster: PREDICTED: hypothetical protein;...    52   3e-05
UniRef50_Q7QWY3 Cluster: GLP_511_47995_52011; n=1; Giardia lambl...    51   4e-05
UniRef50_Q9TXP3 Cluster: Mtm (Myotubularin) family protein 5; n=...    50   8e-05
UniRef50_UPI00006CBEEF Cluster: hypothetical protein TTHERM_0030...    50   1e-04
UniRef50_Q7Z401 Cluster: C-myc promoter-binding protein; n=38; T...    50   1e-04
UniRef50_Q618J0 Cluster: Putative uncharacterized protein CBG146...    50   1e-04
UniRef50_A2FP91 Cluster: Putative uncharacterized protein; n=1; ...    49   2e-04
UniRef50_UPI0000D55CBA Cluster: PREDICTED: similar to CG5627-PA;...    49   2e-04
UniRef50_Q4SLY3 Cluster: Chromosome 13 SCAF14555, whole genome s...    48   3e-04
UniRef50_UPI0000498B81 Cluster: conserved hypothetical protein; ...    48   4e-04
UniRef50_A2ETM8 Cluster: Putative uncharacterized protein; n=1; ...    48   4e-04
UniRef50_A2DB21 Cluster: Putative uncharacterized protein; n=1; ...    48   4e-04
UniRef50_Q54DZ1 Cluster: Putative uncharacterized protein; n=1; ...    47   7e-04
UniRef50_UPI00004992B0 Cluster: DENN domain protein; n=1; Entamo...    47   0.001
UniRef50_UPI000049905F Cluster: conserved hypothetical protein; ...    47   0.001
UniRef50_A2FCC6 Cluster: Putative uncharacterized protein; n=1; ...    47   0.001
UniRef50_Q68D51-2 Cluster: Isoform 2 of Q68D51 ; n=3; Tetrapoda|...    46   0.002
UniRef50_Q4DA74 Cluster: Putative uncharacterized protein; n=1; ...    46   0.002
UniRef50_A4H3X7 Cluster: Putative uncharacterized protein; n=2; ...    46   0.002
UniRef50_A0D955 Cluster: Chromosome undetermined scaffold_41, wh...    46   0.002
UniRef50_UPI00006CAAB7 Cluster: DENN (AEX-3) domain protein; n=1...    45   0.003
UniRef50_UPI00005841BF Cluster: PREDICTED: hypothetical protein;...    45   0.003
UniRef50_Q9D5B9 Cluster: Adult male testis cDNA, RIKEN full-leng...    45   0.003
UniRef50_A2DP70 Cluster: Putative uncharacterized protein; n=1; ...    45   0.003
UniRef50_UPI0000499718 Cluster: hypothetical protein 43.t00023; ...    45   0.004
UniRef50_A2E7C4 Cluster: UDENN domain containing protein; n=2; T...    44   0.005
UniRef50_UPI0000499FB9 Cluster: hypothetical protein 56.t00003; ...    44   0.007
UniRef50_UPI000066125D Cluster: UPI000066125D related cluster; n...    44   0.007
UniRef50_Q54JN1 Cluster: DENN domain-containing protein; n=1; Di...    44   0.007
UniRef50_UPI000049A5D5 Cluster: hypothetical protein 405.t00005;...    44   0.009
UniRef50_Q95Z85 Cluster: Putative uncharacterized protein L3291....    43   0.012
UniRef50_A2G8A8 Cluster: Putative uncharacterized protein; n=1; ...    43   0.016
UniRef50_A2DZM1 Cluster: Putative uncharacterized protein; n=1; ...    43   0.016
UniRef50_A2E9J8 Cluster: Putative uncharacterized protein; n=1; ...    42   0.036
UniRef50_A0EFY5 Cluster: Chromosome undetermined scaffold_94, wh...    41   0.048
UniRef50_A0E249 Cluster: Chromosome undetermined scaffold_74, wh...    41   0.048
UniRef50_UPI0000499593 Cluster: hypothetical protein 43.t00017; ...    41   0.063
UniRef50_Q245U2 Cluster: Putative uncharacterized protein; n=1; ...    41   0.063
UniRef50_UPI00006CB637 Cluster: hypothetical protein TTHERM_0044...    40   0.083
UniRef50_A2FDU6 Cluster: Putative uncharacterized protein; n=1; ...    40   0.11 
UniRef50_UPI00004990AD Cluster: conserved hypothetical protein; ...    40   0.15 
UniRef50_UPI0000E45EF0 Cluster: PREDICTED: hypothetical protein,...    39   0.25 
UniRef50_Q22ZG4 Cluster: DENN (AEX-3) domain; n=1; Tetrahymena t...    39   0.25 
UniRef50_Q9M9A7 Cluster: F27J15.16; n=1; Arabidopsis thaliana|Re...    38   0.34 
UniRef50_A0DZU7 Cluster: Chromosome undetermined scaffold_70, wh...    38   0.34 
UniRef50_Q9FJA0 Cluster: Gb|AAD21756.1; n=3; Arabidopsis thalian...    38   0.44 
UniRef50_A2DC37 Cluster: Putative uncharacterized protein; n=1; ...    38   0.44 
UniRef50_A0CCY9 Cluster: Chromosome undetermined scaffold_169, w...    38   0.44 
UniRef50_A2G1U2 Cluster: Putative uncharacterized protein; n=1; ...    38   0.59 
UniRef50_Q236Q2 Cluster: Putative uncharacterized protein; n=1; ...    37   0.78 
UniRef50_A2DXN2 Cluster: Putative uncharacterized protein; n=1; ...    37   0.78 
UniRef50_A0EC60 Cluster: Chromosome undetermined scaffold_89, wh...    37   0.78 
UniRef50_A2ENJ0 Cluster: Putative uncharacterized protein; n=1; ...    36   1.4  
UniRef50_Q8SS14 Cluster: CYCLIN B-LIKE GUANINE NUCLEOTIDE BINDIN...    36   1.4  
UniRef50_A6RXE1 Cluster: Putative uncharacterized protein; n=2; ...    36   1.4  
UniRef50_A0GXF2 Cluster: Sensor protein; n=2; Chloroflexus|Rep: ...    36   1.8  
UniRef50_Q22ZD3 Cluster: Putative uncharacterized protein; n=2; ...    36   1.8  
UniRef50_Q17L72 Cluster: Map-kinase activating death domain prot...    36   1.8  
UniRef50_Q2UHD0 Cluster: Predicted protein; n=14; Pezizomycotina...    36   1.8  
UniRef50_UPI00006A1CCB Cluster: DENN/MADD domain containing 4B.;...    36   2.4  
UniRef50_Q0FR11 Cluster: Chemotaxis multidomain, CheB methyleste...    35   3.1  
UniRef50_A0CPR0 Cluster: Chromosome undetermined scaffold_23, wh...    35   3.1  
UniRef50_Q39RW8 Cluster: Sensor protein; n=2; Deltaproteobacteri...    35   4.1  
UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=...    35   4.1  
UniRef50_Q23U73 Cluster: Putative uncharacterized protein; n=1; ...    35   4.1  
UniRef50_UPI00006CAA79 Cluster: hypothetical protein TTHERM_0067...    34   5.5  
UniRef50_Q23VY8 Cluster: Putative uncharacterized protein; n=1; ...    34   5.5  
UniRef50_A2EUI7 Cluster: Clan CA, family C19, ubiquitin hydrolas...    34   5.5  
UniRef50_UPI0000D5576A Cluster: PREDICTED: similar to CG9451-PA;...    34   7.2  
UniRef50_UPI00006CEB59 Cluster: hypothetical protein TTHERM_0037...    34   7.2  
UniRef50_Q2GGB5 Cluster: Putative uncharacterized protein; n=6; ...    34   7.2  
UniRef50_A2Q963 Cluster: Contig An01c0240, complete genome; n=1;...    34   7.2  
UniRef50_UPI0000584A98 Cluster: PREDICTED: hypothetical protein ...    33   9.6  
UniRef50_Q97DY8 Cluster: Predicted amidohydrolase; n=26; Clostri...    33   9.6  
UniRef50_Q9FX15 Cluster: F12G12.11 protein; n=1; Arabidopsis tha...    33   9.6  
UniRef50_Q9Y573 Cluster: Actin-binding protein IPP; n=29; Eutele...    33   9.6  

>UniRef50_UPI000051A218 Cluster: PREDICTED: similar to CG18659-PA,
           isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG18659-PA, isoform A - Apis mellifera
          Length = 694

 Score =  358 bits (881), Expect = 1e-97
 Identities = 176/323 (54%), Positives = 237/323 (73%), Gaps = 7/323 (2%)

Query: 58  KLLNCIANIINSPERDQLHSFLEACRIRP-PMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           K LN IA ++++   ++L  FLE     P P+PG ++ +        F CQ P   +LPS
Sbjct: 104 KFLNNIATLMSNGTGEELWKFLETVYKSPVPIPGSSISIPVPNSKVNFVCQSPKQFQLPS 163

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQH 176
           IP+N NLTEY+SAVD   M  ++A++L+ERR+   + + SRLSACVQA NA ++PM WQH
Sbjct: 164 IPENRNLTEYYSAVDAHNMMIIFASMLYERRIIFTSKRLSRLSACVQACNALIYPMIWQH 223

Query: 177 IFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL 236
           I+IP+LP  L+DY+LAPMPFLIGVP   ++ V  S++G+VVILD D N + SPF DLE+L
Sbjct: 224 IYIPVLPLSLIDYLLAPMPFLIGVPTPTLQRVHKSDLGEVVILDADVNIIDSPFQDLESL 283

Query: 237 PPELISSLKKALSDKNA-LGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT 295
           P +++++LKKAL +++A LGD VSRAFLRALV L  GYRDA+ +E GQ ITFN  AFV++
Sbjct: 284 PQDVVTNLKKALRNRSALLGDGVSRAFLRALVQLTAGYRDALTLEQGQSITFNQNAFVES 343

Query: 296 R-KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQ 354
           R  +MQPFLRK+L+ QIFQQFI+ERL++LNSG GF+DEFE+E  +Y+ K    SG K  Q
Sbjct: 344 RPSSMQPFLRKMLELQIFQQFIEERLNMLNSGLGFSDEFEMEACSYSAK----SGSKFMQ 399

Query: 355 QYRDWAKTVKKEGGAFFKTVKDK 377
           QYR+W  T++KE  AFF++VKDK
Sbjct: 400 QYREWTYTMRKESSAFFRSVKDK 422



 Score = 71.3 bits (167), Expect = 4e-11
 Identities = 29/60 (48%), Positives = 44/60 (73%)

Query: 1  MGSRVRETVKFLFELFCEVSPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKLL 60
          MGSR+R+ V+ LFE FCE++     K P++L KYP S+ +EE +KS+PKF +PC +E ++
Sbjct: 1  MGSRLRDNVQHLFECFCEIAAPLGEKPPWILQKYPTSFLDEEILKSVPKFAYPCEIENVM 60


>UniRef50_UPI0000D576CF Cluster: PREDICTED: similar to CG18659-PA,
           isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG18659-PA, isoform A - Tribolium castaneum
          Length = 787

 Score =  355 bits (872), Expect = 1e-96
 Identities = 178/323 (55%), Positives = 234/323 (72%), Gaps = 7/323 (2%)

Query: 58  KLLNCIANIINSPERDQLHSFLEAC-RIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           K L+ IA ++ SP  + L  FL A    +    G    V +N G S F+ + P   +LPS
Sbjct: 104 KFLDNIAVLMTSPRSEDLSEFLSAVYNTKLAEAGKYFTVPFNRGESNFSVEVPKPFQLPS 163

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQH 176
           IP+N NLTEY++AVD+  M  ++A++L+ERR+   + K  RLSACVQ+AN  ++PM WQH
Sbjct: 164 IPENRNLTEYYNAVDSHNMMIIFASMLYERRIIFTSKKLKRLSACVQSANDVIYPMIWQH 223

Query: 177 IFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL 236
           IFIP+LP  L+DY+LAPMPFLIGVP  VM+ V+  EIG+VVILD DAN + +PF+DL  L
Sbjct: 224 IFIPVLPMALIDYLLAPMPFLIGVPEEVMKKVQRHEIGEVVILDADANTVTTPFDDLNNL 283

Query: 237 PPELISSLKKALSDKNA-LGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT 295
           P E+I+SLK+ L +K+A LGD VSRAFLRALV LIGGYRD ++I+  Q ITF+ E F++T
Sbjct: 284 PQEVITSLKRQLKNKSALLGDGVSRAFLRALVQLIGGYRDGLRIQEAQKITFDQEKFIET 343

Query: 296 RK-NMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQ 354
           R  + QPFLR++L  QIFQQFI+ERL +LN+G GF+DEFE+E   Y    +  SG KLKQ
Sbjct: 344 RPVSFQPFLREMLHLQIFQQFIEERLAMLNNGLGFSDEFEMETFRY----SVQSGSKLKQ 399

Query: 355 QYRDWAKTVKKEGGAFFKTVKDK 377
           QY+DW  T+KKEG AFFK+VK+K
Sbjct: 400 QYKDWTSTMKKEGSAFFKSVKEK 422



 Score = 70.9 bits (166), Expect = 5e-11
 Identities = 52/174 (29%), Positives = 84/174 (48%), Gaps = 9/174 (5%)

Query: 1   MGSRVRETVKFLFELFCEVSPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEK-L 59
           MGSR+RE VK  FE FCEV P    K  +++ +YP+ YK+EE +K++P F +P   E  +
Sbjct: 1   MGSRIRENVKHFFECFCEVVPPTGDKAAWIIQQYPDKYKDEEVLKAVPNFAYPYKFENTV 60

Query: 60  LNCIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPD 119
           +   + ++   E      F   CR  P      + + Y   H  F     +   L + P 
Sbjct: 61  IQHYSFVLTDLESKWTFGF---CRHDPRGETAIVVLSYLPWHQAFYKFLDNIAVLMTSPR 117

Query: 120 NCNLTEYFSAV-DTK-CMAGLWAALLHER---RVAIVASKPSRLSACVQAANAT 168
           + +L+E+ SAV +TK   AG +  +   R     ++   KP +L +  +  N T
Sbjct: 118 SEDLSEFLSAVYNTKLAEAGKYFTVPFNRGESNFSVEVPKPFQLPSIPENRNLT 171


>UniRef50_UPI00015B4183 Cluster: PREDICTED: similar to GA15037-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15037-PA - Nasonia vitripennis
          Length = 957

 Score =  338 bits (832), Expect = 1e-91
 Identities = 172/328 (52%), Positives = 234/328 (71%), Gaps = 12/328 (3%)

Query: 58  KLLNCIANIINSPERDQLHSFL-EACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           KLLN IA +  S     L  FL +      P+ G ++ +      + F CQ P   +LPS
Sbjct: 104 KLLNNIATLTASKNAGDLWKFLGDVYEATIPVSGASISIPLPDCKTTFVCQRPKQFQLPS 163

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQH 176
           IP+N NLTEYFSAVD+  M  ++A++L+ERR+   + + SRLSACVQA NA ++PM WQH
Sbjct: 164 IPENRNLTEYFSAVDSHNMMMVFASMLYERRIIFTSKRLSRLSACVQACNALIYPMIWQH 223

Query: 177 IFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL 236
           I+IP+LP  L DY+LAPMPFLIGVP  ++++VR S++G+VVILD D + + SPF DLE+L
Sbjct: 224 IYIPVLPLSLTDYLLAPMPFLIGVPSPILKSVRQSDLGEVVILDADNSTIESPFQDLESL 283

Query: 237 PPELISSLKKALSDKNA-LGDAVSRAFLRALVCLIGGYRDAIKIENGQ-----LITFNPE 290
           P +++++L++AL ++ A LGD VSRAFLRALV L  GYR+A+ ++ GQ      ITF+ E
Sbjct: 284 PQDVVTNLRRALRNRPALLGDGVSRAFLRALVQLTAGYREALTLQQGQSDEHVRITFDQE 343

Query: 291 AFVKTRK-NMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSG 349
           AFV++R  +MQPFLRK+L+ QIFQQFI+ERL +LNSG GF+DEFE+E   Y+DK    SG
Sbjct: 344 AFVESRPISMQPFLRKMLELQIFQQFIEERLHMLNSGLGFSDEFEMEACNYSDK----SG 399

Query: 350 QKLKQQYRDWAKTVKKEGGAFFKTVKDK 377
            K  QQYR+W   ++KEG AF ++VKDK
Sbjct: 400 SKFMQQYREWTYAMRKEGSAFIRSVKDK 427



 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 32/60 (53%), Positives = 45/60 (75%)

Query: 1  MGSRVRETVKFLFELFCEVSPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKLL 60
          MGSR+RE VK LFE FCEV+  +  K+ ++L +YPESY + E +KS+PKF +PC LE ++
Sbjct: 1  MGSRLRENVKQLFECFCEVAQPNGEKQAWILQRYPESYNDSEVLKSVPKFAYPCELENVV 60


>UniRef50_Q8TEH3 Cluster: DENN domain-containing protein 1A; n=51;
           Eumetazoa|Rep: DENN domain-containing protein 1A - Homo
           sapiens (Human)
          Length = 1009

 Score =  284 bits (697), Expect = 2e-75
 Identities = 153/324 (47%), Positives = 207/324 (63%), Gaps = 16/324 (4%)

Query: 58  KLLNCIANIINSPERDQLHSFLEACRIRP-PMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           KLLN +A+     + +Q +  LE     P P PG +   ++ + HS FT   PD+ +LPS
Sbjct: 111 KLLNILADYTTKRQENQWNELLETLHKLPIPDPGVS---VHLSVHSYFTV--PDTRELPS 165

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQH 176
           IP+N NLTEYF AVD   M  L+A++L+ERR+ I+ SK S L+AC+  + A L+PM WQH
Sbjct: 166 IPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQH 225

Query: 177 IFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL 236
           ++IP+LP HL+DY  APMP+LIG+  S+ME VR   + DVVIL+VD N L +PF+DL++L
Sbjct: 226 VYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSL 285

Query: 237 PPELISSLKKALSD-KNALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT 295
           P ++ISSLK  L       GD V+RAFL+A     G YR+A+KIE  + ITF  EAFV  
Sbjct: 286 PNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSH 345

Query: 296 RKN--MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLK 353
            ++  M+ FL+   Q Q+F+QFID RLDLLNSG GF+D FE       +++N G      
Sbjct: 346 YRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFE-------EEINMGEYAGSD 398

Query: 354 QQYRDWAKTVKKEGGAFFKTVKDK 377
           + Y  W  TV+K  GA   TVK K
Sbjct: 399 KLYHQWLSTVRKGSGAILNTVKTK 422



 Score = 46.0 bits (104), Expect = 0.002
 Identities = 21/62 (33%), Positives = 39/62 (62%), Gaps = 3/62 (4%)

Query: 1  MGSRVRETVKFLFELFCEVS---PGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLE 57
          MGSR+++  +  FE++ EV+    G  L +P V  ++PE Y ++E ++++ KF FP  ++
Sbjct: 1  MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVD 60

Query: 58 KL 59
           L
Sbjct: 61 SL 62


>UniRef50_A1Z7Q5 Cluster: CG18659-PA, isoform A; n=3;
           Sophophora|Rep: CG18659-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 908

 Score =  268 bits (656), Expect = 2e-70
 Identities = 143/305 (46%), Positives = 202/305 (66%), Gaps = 7/305 (2%)

Query: 58  KLLNCIANIINSPERDQLHSFL-EACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           KLL  +A +  + + +   +FL EA     P  G +LKV Y+AG S FT + P   +LPS
Sbjct: 117 KLLPVLAELRRT-DPNGFRTFLSEAYNQGIPDCGGSLKVYYSAGQSHFTFERPLQFQLPS 175

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQH 176
           +P+N NL  Y++ V+ K M  ++AA+L ERR+   +    RLS+C+QAANA L+PM WQH
Sbjct: 176 MPENHNLNLYYNFVEPKEMIAVFAAMLAERRIIFTSRHLDRLSSCIQAANAFLYPMVWQH 235

Query: 177 IFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL 236
           IFIP+LP    DY+ APMP+LIGVP  V+E V   E+G+VVIL+ D     SPF+D+  L
Sbjct: 236 IFIPVLPWEFKDYLGAPMPYLIGVPEPVLETVTSDELGEVVILNCDTKIFESPFDDVHNL 295

Query: 237 PPELISSLKKALS-DKNALGDAVSRAFLRALVCLIGGYRDAIKI-ENGQLITFNPEAFVK 294
           P E++S LKK L+   + +GD +S+ FL ALV LIGGYRDA++  EN +  TFN + F++
Sbjct: 296 PTEIVSQLKKHLNHTHDHIGDRISKIFLNALVQLIGGYRDAVEYHENSK--TFNSQKFIE 353

Query: 295 TR-KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLK 353
           +R  +++PFL K++  QIF QFID+RL +LNSG GF+DEFE+E   YA+K   G    + 
Sbjct: 354 SRPAHLRPFLAKMMDLQIFAQFIDDRLTMLNSGLGFSDEFELETVRYAEKKKRGRNYAIM 413

Query: 354 QQYRD 358
           +  +D
Sbjct: 414 KNLKD 418



 Score = 45.6 bits (103), Expect = 0.002
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 13/67 (19%)

Query: 1  MGSRVRETVKFLFELFCEVSP-------------GDHLKEPYVLFKYPESYKNEEEIKSI 47
          MGSR++  VK LFE +CEV+P             G  +    ++  +PE ++++E +  I
Sbjct: 1  MGSRIKNDVKKLFEFWCEVTPTPGLERGTSSRSGGPAVPAGVIVESFPEGFRDQEVLTGI 60

Query: 48 PKFTFPC 54
          P F FPC
Sbjct: 61 PSFAFPC 67


>UniRef50_Q6P3S1 Cluster: DENN domain-containing protein 1B; n=33;
           Euteleostomi|Rep: DENN domain-containing protein 1B -
           Homo sapiens (Human)
          Length = 426

 Score =  252 bits (617), Expect = 1e-65
 Identities = 124/238 (52%), Positives = 168/238 (70%), Gaps = 4/238 (1%)

Query: 101 HSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSA 160
           HS F    PD   LP+IP++ NLTEYF AVD   M  L+A++LHERR+ I++SK S L+A
Sbjct: 170 HSYFIA--PDVTGLPTIPESRNLTEYFVAVDVNNMLQLYASMLHERRIVIISSKLSTLTA 227

Query: 161 CVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILD 220
           C+  + A L+PM WQHI+IP+LP HL+DY  APMP+LIG+  S++E V+   + DVV+L+
Sbjct: 228 CIHGSAALLYPMYWQHIYIPVLPPHLLDYCCAPMPYLIGIHSSLIERVKNKSLEDVVMLN 287

Query: 221 VDANELRSPFNDLETLPPELISSLKKALSDKN-ALGDAVSRAFLRALVCLIGGYRDAIKI 279
           VD N L SPF+DL  LP +++S+LK  L  ++ A GD V+RAFLRA   L G YRDA++ 
Sbjct: 288 VDTNTLESPFSDLNNLPSDVVSALKNKLKKQSTATGDGVARAFLRAQAALFGSYRDALRY 347

Query: 280 ENGQLITFNPEAFVKTRKN-MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVE 336
           + G+ ITF  E+FVK R + M+ FL   +  Q+F+QFID RL  LN+GRGF+D FE E
Sbjct: 348 KPGEPITFCEESFVKHRSSVMKQFLETAINLQLFKQFIDGRLAKLNAGRGFSDVFEEE 405



 Score = 41.1 bits (92), Expect = 0.048
 Identities = 17/52 (32%), Positives = 33/52 (63%), Gaps = 3/52 (5%)

Query: 8  TVKFLFELFCEVSPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKL 59
          T   + ++ C  S  +   +P VL+K+PE + ++E ++S+PKF FP  +E++
Sbjct: 12 TFDLVLKVKCHASENE---DPVVLWKFPEDFGDQEILQSVPKFCFPFDVERV 60


>UniRef50_Q8IV53 Cluster: DENN domain-containing protein 1C; n=12;
           Tetrapoda|Rep: DENN domain-containing protein 1C - Homo
           sapiens (Human)
          Length = 801

 Score =  248 bits (606), Expect = 3e-64
 Identities = 132/273 (48%), Positives = 177/273 (64%), Gaps = 11/273 (4%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANAT 168
           PDS +LPSIP+N NLTE   AV  + + GL+AALL ERRV + ASK S L++CV A+ A 
Sbjct: 178 PDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLSTLTSCVHASCAL 237

Query: 169 LFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS 228
           L+PM W+H+ IP LP HL+DY  APMP+LIGV  S+ E VR   + DVV+L+VDAN L +
Sbjct: 238 LYPMRWEHVLIPTLPPHLLDYCCAPMPYLIGVHASLAERVREKALEDVVVLNVDANTLET 297

Query: 229 PFNDLETLPPELISSLKKALSDKNAL--GDAVSRAFLRALVCLIGGYRDAIKIENGQLIT 286
            FND++ LPP+++S L+  L  K AL  G+ VSR FL+A   L GGYRDA+    GQ +T
Sbjct: 298 TFNDVQALPPDVVSLLRLRLR-KVALAPGEGVSRLFLKAQALLFGGYRDALVCSPGQPVT 356

Query: 287 FNPEAFV--KTRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKL 344
           F+ E F+  K    +Q F R+ +  Q+F+QFI+ RL+ LN G GF+D+FE E        
Sbjct: 357 FSEEVFLAQKPGAPLQAFHRRAVHLQLFKQFIEARLEKLNKGEGFSDQFEQEIT------ 410

Query: 345 NTGSGQKLKQQYRDWAKTVKKEGGAFFKTVKDK 377
             G+     + Y+ WA  +KK GGA   +VK K
Sbjct: 411 GCGASSGALRSYQLWADNLKKGGGALLHSVKAK 443



 Score = 37.9 bits (84), Expect = 0.44
 Identities = 17/59 (28%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 1  MGSRVRETVKFLFELFCEVS-PGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEK 58
          M SR       +F+ F E + P    ++P +L ++P  ++++E ++ +PKF FP  +E+
Sbjct: 1  MESRAEGGSPAVFDWFFEAACPASLQEDPPILRQFPPDFRDQEAMQMVPKFCFPFDVER 59


>UniRef50_Q6DCI3 Cluster: LOC446246 protein; n=2; Xenopus|Rep:
           LOC446246 protein - Xenopus laevis (African clawed frog)
          Length = 730

 Score =  245 bits (599), Expect = 2e-63
 Identities = 137/322 (42%), Positives = 186/322 (57%), Gaps = 13/322 (4%)

Query: 58  KLLNCIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSI 117
           KLLN IA  +   +  ++   L+     P    +T   +    + +     PD  +LPS+
Sbjct: 108 KLLNNIAEYLAKDQSVEICDLLQTVYHHPVPQENTALSLEMLSYFI----APDPTRLPSV 163

Query: 118 PDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHI 177
           P+N NLTE+  AV    M  L+++LL ERR+ I +SK S L+ACV A+ A L+PM WQHI
Sbjct: 164 PENRNLTEFLVAVQVDTMLHLYSSLLCERRILITSSKLSTLTACVHASAALLYPMYWQHI 223

Query: 178 FIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
           +IP LP HL+DY  APMP+LIGV  S+ME V +  + DVVI ++D N L +PF DL+ LP
Sbjct: 224 YIPTLPPHLLDYCSAPMPYLIGVHSSLMEKVNIKSLEDVVIFNMDTNNLETPFKDLDNLP 283

Query: 238 PELISSLKKALSDKNA-LGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTR 296
           P ++S LK  L    A +GD VS  FL+A   L GGYRDA+    GQ I F  E+F+  +
Sbjct: 284 PHVVSLLKLRLKKPCAVMGDGVSHVFLKAQALLFGGYRDALIYTPGQAICFCQESFLNHK 343

Query: 297 -KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQQ 355
              M+ FL+  +  Q+F QFID RLD LN+G GF D FE E        N G     K  
Sbjct: 344 CSAMRSFLQNAIHLQLFTQFIDSRLDKLNAGVGFTDAFEQEIT------NCGLSGNSK-S 396

Query: 356 YRDWAKTVKKEGGAFFKTVKDK 377
           Y+ W + +KK GG+    VK +
Sbjct: 397 YQMWLEHLKKGGGSLINNVKSR 418



 Score = 39.5 bits (88), Expect = 0.15
 Identities = 18/62 (29%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 1  MGSRVRETVKFLFELFCEVSPGDHL-KEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKL 59
          MGSR++E    +F+ F EV     L ++P +  ++PE + +++ + ++ +F FP  +E+ 
Sbjct: 1  MGSRIKENPDKIFDGFFEVLRPTALDQDPVLQMQFPEHFDDQDSVTTLTRFCFPFDVERW 60

Query: 60 LN 61
           N
Sbjct: 61 EN 62


>UniRef50_Q8CFK6 Cluster: DENN domain-containing protein 1C; n=6;
           Mammalia|Rep: DENN domain-containing protein 1C - Mus
           musculus (Mouse)
          Length = 786

 Score =  238 bits (582), Expect = 2e-61
 Identities = 137/311 (44%), Positives = 191/311 (61%), Gaps = 18/311 (5%)

Query: 71  ERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAV 130
           E D   +    C I PP  G++ K++     S F    PD+  LPSIP+N NLTE   AV
Sbjct: 148 EMDSSITVRSECGILPPALGNS-KLL-----SCFVA--PDAASLPSIPENRNLTELVVAV 199

Query: 131 DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
             + + GL+AALL ERRV + ASK S L+ACV A+ A L+PM W+H+ IP LP HL+DY 
Sbjct: 200 TDENIVGLFAALLAERRVLLTASKLSTLTACVHASCALLYPMRWEHVLIPTLPPHLLDYC 259

Query: 191 LAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSD 250
            APMP+LIGV  S+ E VR   + DVV+L+ D+N L +PF+D++ LPP+++S L+  L  
Sbjct: 260 CAPMPYLIGVHGSLAERVREKALEDVVVLNADSNTLETPFDDVQALPPDVVSLLRLRLR- 318

Query: 251 KNAL--GDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFV--KTRKNMQPFLRKI 306
           K AL  G+ VSR FL+    L GGYRDA+    GQ +TF+ EAF+  K    +Q F +K 
Sbjct: 319 KVALSPGEGVSRLFLKVQALLFGGYRDALVCIPGQPVTFSEEAFLAQKPGAPLQAFHKKA 378

Query: 307 LQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQQYRDWAKTVKKE 366
           +  Q+F+QFI+ RL+ LN+G GF+D+FE E  A       G+     + Y+ W  ++KK 
Sbjct: 379 VHLQLFKQFIESRLEKLNAGEGFSDQFEQEIIAC-----RGASSGTLRSYQLWVDSLKKG 433

Query: 367 GGAFFKTVKDK 377
             A   ++K K
Sbjct: 434 SDALLHSMKTK 444



 Score = 36.7 bits (81), Expect = 1.0
 Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 1/59 (1%)

Query: 1  MGSRVRETVKFLFELFCEVSPGDHLKE-PYVLFKYPESYKNEEEIKSIPKFTFPCSLEK 58
          MGS        +F+ F E    + L+E P +L ++P  ++ +E ++ +P+F FP  +E+
Sbjct: 1  MGSTETRHPPAMFDWFFEAGCPNSLEEDPPILRQFPPDFQEQEAMQMVPRFCFPFDIER 59


>UniRef50_Q4TJ11 Cluster: Chromosome undetermined SCAF1129, whole
           genome shotgun sequence; n=6; Tetraodontidae|Rep:
           Chromosome undetermined SCAF1129, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 473

 Score =  227 bits (554), Expect = 5e-58
 Identities = 150/373 (40%), Positives = 204/373 (54%), Gaps = 65/373 (17%)

Query: 58  KLLNCIANIINSPERDQLHSFLEACRIRP-PMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           KLLN +A+     +  Q    L +    P P PG  + V     HS      PD  +LPS
Sbjct: 96  KLLNILADYTIRGQTRQWQDLLVSLHTLPVPEPG--VPVHLGVHHSF---AAPDLQELPS 150

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASK-------PS------------- 156
           IP+N NLTEYF AVD   M  L+A++LHERR+ I +SK       PS             
Sbjct: 151 IPENRNLTEYFVAVDVNNMLHLYASMLHERRILICSSKLSTVSPAPSLPLLAWTGSSVLT 210

Query: 157 ----RLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSE 212
               +L+ACV  A A L PM WQH++IP+LP+HL+DY  APMP+LIGV  S+ME V+   
Sbjct: 211 SHCPQLTACVHGAAALLCPMHWQHVYIPVLPQHLLDYCCAPMPYLIGVHASLMEKVQRLS 270

Query: 213 IGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNAL-GDAVSRAFLRALVCLIG 271
           + DVV+L+VD N L +P+NDL+ LP +++ +LK  L   +   GD V+R FL++   L G
Sbjct: 271 LDDVVVLNVDTNTLETPYNDLQNLPGDVVLALKSRLKKVSTTPGDGVARVFLKSQAALFG 330

Query: 272 GYRDAIKIENGQLITFNPEAFVKTR-KNMQPFLRKILQSQIFQ----------------- 313
            YRDA+++  G+ ITFN + FV  R  +M+ FL   +Q Q+F+                 
Sbjct: 331 SYRDALQMVPGEPITFNEDLFVNHRSSSMRLFLHNAIQLQLFKQVLTHTHTHPHTHMRVC 390

Query: 314 ---------QFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQQYRDWAKTVK 364
                    QFID RL+LLNSG GFND FE E +     ++  +G    + Y  W  T+K
Sbjct: 391 GGGVTDWCLQFIDGRLNLLNSGEGFNDAFEEEIS-----MSEYAGS--DRTYHQWLLTMK 443

Query: 365 KEGGAFFKTVKDK 377
           K GGA F TV+ K
Sbjct: 444 KGGGAIFNTVRTK 456



 Score = 35.9 bits (79), Expect = 1.8
 Identities = 16/47 (34%), Positives = 29/47 (61%), Gaps = 1/47 (2%)

Query: 14 ELFCEVSP-GDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKL 59
          E++ EV+  G     P V  ++PE Y ++E + ++P+F FP S++ L
Sbjct: 1  EVYVEVARLGPQGSGPEVQRRFPEDYTDQETLLTVPRFCFPFSMDSL 47


>UniRef50_UPI000056B3F1 Cluster: UPI000056B3F1 related cluster; n=2;
           Danio rerio|Rep: UPI000056B3F1 UniRef100 entry - Danio
           rerio
          Length = 698

 Score =  201 bits (490), Expect = 3e-50
 Identities = 98/181 (54%), Positives = 130/181 (71%), Gaps = 3/181 (1%)

Query: 101 HSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSA 160
           H  FT   PD  +LPSIP+N NLTEYF AVD   M  L+A++L+ERR+ I  SK S L+A
Sbjct: 50  HLFFTV--PDPRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILISCSKLSTLTA 107

Query: 161 CVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILD 220
           CV  A A L+PM WQH++IP+LP+HL+DY  APMP+LIGV  S+ME VR   + DVV+L+
Sbjct: 108 CVHGAAAMLYPMYWQHVYIPVLPQHLLDYCCAPMPYLIGVHSSLMEKVRGMALDDVVLLN 167

Query: 221 VDANELRSPFNDLETLPPELISSLKKALSD-KNALGDAVSRAFLRALVCLIGGYRDAIKI 279
           VD N L +PF+DL++LP +++SSLK  L    ++ GD V+RAFL+A   L G YR+A+ I
Sbjct: 168 VDTNTLETPFDDLQSLPNDVVSSLKNRLRKVSSSTGDGVARAFLKAQAALFGSYRNALHI 227

Query: 280 E 280
           E
Sbjct: 228 E 228


>UniRef50_Q20473 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 661

 Score =  192 bits (469), Expect = 1e-47
 Identities = 107/300 (35%), Positives = 176/300 (58%), Gaps = 13/300 (4%)

Query: 50  FTFPCSLEKLLNCIANIINSPERDQLHSFL-EACRIRPPMPGHTLKVI---YNAGHS--- 102
           F +P    K LN I+ +I S +R+ + S L +      P     L+        GH+   
Sbjct: 101 FFWPNVFFKALNDISLVIGSAQREDVESVLTKFYHTDIPNIDEYLRFADSNQTDGHNYRV 160

Query: 103 VFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACV 162
           VF  + PD  +LP++  +    E+++A+D + M  ++A+LL ERR+     K   LS+C+
Sbjct: 161 VFAEKIPDHTRLPTLGSDKFFLEFYNAIDPRQMLAIFASLLKERRILFTGRKVGSLSSCL 220

Query: 163 QAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMS--EIGDVVILD 220
            A +  L+PM WQ +FI ILP+ LVD ++APMP+LIGVP++V+EN R++  +IG+VVI+D
Sbjct: 221 HAVSMLLYPMCWQSVFITILPESLVDMVMAPMPYLIGVPKTVLENARLNIRDIGEVVIVD 280

Query: 221 VDANELRSPFNDLETLPPELISSLKKALSDKNALGDAVSRAFLRALVCLIGGYRDAIKIE 280
           +D   L SPF+D+  +P E+++ LK  L  ++A+ D  ++ FLRA+V L G Y      +
Sbjct: 281 IDEKTLTSPFDDVAAMPQEVVNFLKAQLRSQSAMDDTFAKHFLRAMVMLFGDYTSGFTGD 340

Query: 281 NGQLITFNPEAFVKTRK-NMQPFLRKILQS---QIFQQFIDERLDLLNSGRGFNDEFEVE 336
             + + F+ E FV  +K + Q ++  +L +   Q  ++FI +RL+L   G    D+FE+E
Sbjct: 341 TPETLVFSKERFVVQQKPSYQAYVSSLLGADGVQYLERFIHDRLELYKDGHVPGDQFEIE 400



 Score = 40.7 bits (91), Expect = 0.063
 Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 1/57 (1%)

Query: 4  RVRETVKFLFELFCEV-SPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKL 59
          R R  V  L+++FCE+ +P    K   +  +YP+ + +   +KS+ +F FPC L ++
Sbjct: 5  RYRADVATLYDVFCELDAPKPGEKLAILRLQYPDDFHDPAIVKSVQQFAFPCQLREV 61


>UniRef50_Q4RJA5 Cluster: Chromosome 18 SCAF15038, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 18 SCAF15038, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 336

 Score =  126 bits (304), Expect = 1e-27
 Identities = 103/345 (29%), Positives = 168/345 (48%), Gaps = 28/345 (8%)

Query: 1   MGSRVRETVKFLFELFCEVS-PGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKL 59
           MGSR++E  +  F  F E + P    ++P V F++PE + +EE  +++P+F FP  ++K+
Sbjct: 1   MGSRLKENPEQTFYWFFEATCPVARDRDPGVQFQFPEDFSDEESCQTLPRFCFPYDIQKV 60

Query: 60  LNCIAN-----IINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKL 114
            + +A      ++   E  Q   F   CR+          + Y     VF        KL
Sbjct: 61  RDGVAVQHFTFVLTDLEGSQRFGF---CRLTTSTHTCLCILSYLPWFEVFY-------KL 110

Query: 115 PSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSW 174
            +     NL +Y        M  L AAL  +    +  S   ++  C    N +LF +  
Sbjct: 111 LN-----NLADYLKKGQMNEMKALLAALYKQPIPLMSGSVTLQMMCC--CLNLSLFAVDI 163

Query: 175 QHIFIPI-LPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDL 233
                      H++   L P      V   ++  VR   + +VVIL+VD+N L +PF+DL
Sbjct: 164 LRARAECCFVSHVLAAHLHPCTTTTSV--GLLLRVRGRALEEVVILNVDSNTLETPFDDL 221

Query: 234 ETLPPELISSLKKALSDKN-ALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAF 292
           + +P +++S LK  L  +  + G  VSRAFL+A   L GGYR+A++ +    + FN   F
Sbjct: 222 KRIPSDVVSGLKLCLKRQAVSPGCGVSRAFLKAQALLFGGYRNALQCQQDGEMLFNEAVF 281

Query: 293 VKTR-KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVE 336
           ++ +  +M+ FL+  +  Q F+QFID R+D+LN G+   D FE E
Sbjct: 282 LEHKSSSMRHFLQSAVHLQFFKQFIDSRMDILNKGKEPGDLFEEE 326


>UniRef50_Q59I62 Cluster: Fc11b09; n=9; Euteleostomi|Rep: Fc11b09 -
            Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1130

 Score =  118 bits (285), Expect = 2e-25
 Identities = 90/299 (30%), Positives = 157/299 (52%), Gaps = 38/299 (12%)

Query: 54   CSLEKL--LNCIANIINSPERDQ------LHSFLEACRIRP-PMPGHTLKV---IYNAGH 101
            C + +L   N  + I++  ER +      ++ F+ +    P P PG T+KV   +  AG+
Sbjct: 784  CVISRLGCFNLFSKILDEVERRRGISAALVYPFMRSVMESPFPAPGKTIKVKTFLPGAGN 843

Query: 102  SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSAC 161
             V   + P  ++L    ++ +L   F+ +  + +  ++A+LL ERRV  VA K S LS+C
Sbjct: 844  EVIELRRPMDSRL----EHVDLESLFNCLSVRQVVRVFASLLLERRVIFVADKLSTLSSC 899

Query: 162  VQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDV 221
            V A  A L+P SWQH FIP+LP  +VD +  P PFL+G+  S +  ++   + + +++D+
Sbjct: 900  VHAVVALLYPFSWQHTFIPVLPTSMVDIVCCPTPFLVGILSSSLPKLKELPVEEALMVDL 959

Query: 222  DANE-LRSPFNDLETLPPELISSLKKALSDKN-----------------ALGDAVSRAFL 263
              +  +R   ++   LP +L ++L+++L  +N                 +L   VS AF+
Sbjct: 960  GTDRFIRQMDDEASLLPRKLQAALEQSLEQRNDIINQDSDSESDEECSTSLNSVVSEAFI 1019

Query: 264  RALVCLIGGYRDAI-KIENGQLITFNPEAFVKT--RKNMQPFLRKILQSQIFQQFIDER 319
            R  +  IG Y   + + E G+ I F  E F K+   K+++ FL   ++SQ+F  FI +R
Sbjct: 1020 RFFLETIGHYSLFLTQGERGERI-FQREPFRKSVASKSIRRFLGVFMESQMFAGFIQDR 1077


>UniRef50_P78524 Cluster: Suppression of tumorigenicity 5; n=36;
            Amniota|Rep: Suppression of tumorigenicity 5 - Homo
            sapiens (Human)
          Length = 1137

 Score =  117 bits (281), Expect = 6e-25
 Identities = 83/269 (30%), Positives = 141/269 (52%), Gaps = 29/269 (10%)

Query: 75   LHSFLEACRIRP-PMPGHTLKV---IYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAV 130
            ++ F+ +    P P PG T+KV   +  AG+ V   + P  ++L  +   C     F+ +
Sbjct: 826  VYPFMRSLMESPFPAPGKTIKVKTFLPGAGNEVLELRRPMDSRLEHVDFEC----LFTCL 881

Query: 131  DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
              + +  ++A+LL ERRV  VA K S LS+C  A  A L+P SWQH FIP+LP  ++D +
Sbjct: 882  SVRQLIRIFASLLLERRVIFVADKLSTLSSCSHAVVALLYPFSWQHTFIPVLPASMIDIV 941

Query: 191  LAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLET-LPPELISSLKKALS 249
              P PFL+G+  S +  ++   + + +++++ ++      +D +T LP +L ++L++AL 
Sbjct: 942  CCPTPFLVGLLSSSLPKLKELPVEEALMVNLGSDRFIRQMDDEDTLLPRKLQAALEQALE 1001

Query: 250  DK----------------NALGDAVSRAFLRALVCLIGGYRDAI-KIENGQLITFNPEAF 292
             K                N L   VS  F+R  V  +G Y   + + E G+   F  EAF
Sbjct: 1002 RKNELISQDSDSDSDDECNTLNGLVSEVFIRFFVETVGHYSLFLTQSEKGER-AFQREAF 1060

Query: 293  VKT--RKNMQPFLRKILQSQIFQQFIDER 319
             K+   K+++ FL   ++SQ+F  FI +R
Sbjct: 1061 RKSVASKSIRRFLEVFMESQMFAGFIQDR 1089


>UniRef50_Q68D51 Cluster: DENN domain-containing protein 2C; n=30;
           Tetrapoda|Rep: DENN domain-containing protein 2C - Homo
           sapiens (Human)
          Length = 928

 Score =  115 bits (276), Expect = 2e-24
 Identities = 92/292 (31%), Positives = 153/292 (52%), Gaps = 31/292 (10%)

Query: 75  LHSFLEACRIRP-PMPGHTLKV---IYNAG-HSVFTCQCPDSNKLPSIPDNCNLTEYFSA 129
           ++ F+ +    P P PG T+ V   +  AG  S+  C+  DS +L  +   C     F  
Sbjct: 621 VYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDS-RLEHVDFKC----LFKC 675

Query: 130 VDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDY 189
           +    +  + A+LL ERRV  VA+  S LS C  A  ATL+P +WQH +IP+LP  ++D 
Sbjct: 676 LSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDI 735

Query: 190 MLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANE-LRSPFNDLETLPPELISSLKKAL 248
           + +P PFLIG+    +  ++   I +V+I+D+ A++ L+   ++ E LPP+L ++L + L
Sbjct: 736 VCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQIL 795

Query: 249 SDKN-------------ALGDAVSRAFLRALVCLIGGYRDAIKI-ENGQLITFNPEAFVK 294
            ++N              L   VS AF+R  V L+G Y   + + E G+ + F  E F K
Sbjct: 796 EERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERV-FQREPFRK 854

Query: 295 --TRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKL 344
             T ++++ FL   +++Q+F  FI +R +L  S  G    FE+    Y + +
Sbjct: 855 SHTSRSVRHFLDLFMETQMFAGFIQDR-ELRKS--GVKGLFEIRAIQYLETI 903


>UniRef50_Q54JA6 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1523

 Score =  108 bits (260), Expect = 2e-22
 Identities = 88/318 (27%), Positives = 151/318 (47%), Gaps = 25/318 (7%)

Query: 73  DQLHSFLEACRIRP-PMPGHTLKV-IYNAGHSV----------FTCQCPDSNKLPSIPDN 120
           D++H+FL A  +   P PG +  V IY+               +T + P S    S+ D 
Sbjct: 178 DEIHNFLAASLLSVIPAPGDSFTVYIYDNPFISDKKPTNLPVSYTLKRPVSTDKSSLHDG 237

Query: 121 CNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIP 180
             L      + ++ +  L+ +LL ERRV I +   +R+S  + A  + L P +WQHIFIP
Sbjct: 238 -TLQPLIETLSSQKLLHLFISLLFERRVIIYSENINRVSKFINAIVSLLDPFAWQHIFIP 296

Query: 181 ILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPEL 240
           ILP+ L+DY  APMPF+IG+  S++  +R   + ++V +D+D +++     D+   P  L
Sbjct: 297 ILPRSLLDYCTAPMPFIIGIHSSLLAPIRRKPLNEIVFVDLDKDQVLPLPEDIAIFPSIL 356

Query: 241 ISSLKKAL--------SDKNALGDAVSRAFLRALVCLIGGYRD-AIKIENGQLITFNPEA 291
           +  LK  L         +K+     +   F +  V ++G YR   +K  + + + F+  +
Sbjct: 357 LQPLKHCLELQILDWKKNKHYDNKIIVETFRKFFVTVLGTYRRFFLKDMDKKKMIFDKIS 416

Query: 292 FVKTRK-NMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADK--LNTGS 348
           F+ ++      F      SQ+F++FI ER +    G      FE E   Y  K  +    
Sbjct: 417 FIDSQLITPTKFFNVFCSSQMFERFIAEREEYYFKGVTPPGIFEKEAVIYDLKHPVTASI 476

Query: 349 GQKLKQQYRDWAKTVKKE 366
              L+ + ++  K  +KE
Sbjct: 477 NNTLRNKEKEKEKEKEKE 494


>UniRef50_UPI0000F20EF1 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
           protein, partial - Danio rerio
          Length = 331

 Score =  107 bits (258), Expect = 4e-22
 Identities = 46/84 (54%), Positives = 62/84 (73%)

Query: 158 LSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVV 217
           L+ACV  + A L+PM WQHIFIP+LP HL+DY  APMP+L+GV  S++E V+   + DVV
Sbjct: 189 LTACVHGSTAMLYPMHWQHIFIPVLPPHLLDYCCAPMPYLVGVHLSLLERVKSRSLEDVV 248

Query: 218 ILDVDANELRSPFNDLETLPPELI 241
           IL+VD N L SP +DL  LP +++
Sbjct: 249 ILNVDTNTLESPTDDLHNLPSDVL 272



 Score = 70.1 bits (164), Expect = 9e-11
 Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 10/102 (9%)

Query: 58  KLLNCIANIINSPERDQLHSFLEACRIRP-PMPGHTLKVIYNAGHSVFTCQCPDSNKLPS 116
           KLLN +A+ ++  + D L+  LE     P P P   + +   A         PD N LP+
Sbjct: 50  KLLNTLADYLSKHQEDDLNDMLETLHNHPVPKPNTPVNLSVVA---------PDINGLPT 100

Query: 117 IPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRL 158
           IP++ NLTEYF AVD   M  L+A++LHERR+ I +SK S L
Sbjct: 101 IPESRNLTEYFVAVDVNNMLHLYASMLHERRIIITSSKLSTL 142


>UniRef50_Q9ULE3 Cluster: DENN domain-containing protein 2A; n=24;
           Euteleostomi|Rep: DENN domain-containing protein 2A -
           Homo sapiens (Human)
          Length = 1009

 Score =  107 bits (258), Expect = 4e-22
 Identities = 78/257 (30%), Positives = 131/257 (50%), Gaps = 26/257 (10%)

Query: 114 LPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMS 173
           L S  ++ +    FS++  + +  ++A+LL ERRV  +A K S LS C  A  A ++P +
Sbjct: 734 LDSRLEHVDFESLFSSLSVRHLVCVFASLLLERRVIFIADKLSILSKCCHAMVALIYPFA 793

Query: 174 WQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILD-VDANELRSPFND 232
           WQH +IP+LP  +VD + +P PFLIG+  S +  +R   + +V+++D V++  LR   ++
Sbjct: 794 WQHTYIPVLPPAMVDIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLVNSRFLRQMDDE 853

Query: 233 LETLPPELISSLKKALSDKN--------------------ALGDAVSRAFLRALVCLIGG 272
              LP +L  +L+  L  +N                     L + VS AF+R  V ++G 
Sbjct: 854 DSILPRKLQVALEHILEQRNELACEQDEGPLDGRHGPESSPLNEVVSEAFVRFFVEIVGH 913

Query: 273 YRDAIKIENGQLITFNPEAFVK--TRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFN 330
           Y   +     +  T   EAF K  + K+++ FL   +++Q+F+ FI ER       +G  
Sbjct: 914 YSLFLTSGEREERTLQREAFRKAVSSKSLRHFLEVFMETQMFRGFIQERELRRQDAKGL- 972

Query: 331 DEFEVECNAYADKLNTG 347
             FEV    Y + L +G
Sbjct: 973 --FEVRAQEYLETLPSG 987


>UniRef50_Q00WT6 Cluster: RAS signaling inhibitor ST5; n=2;
           Ostreococcus|Rep: RAS signaling inhibitor ST5 -
           Ostreococcus tauri
          Length = 633

 Score =  103 bits (246), Expect = 1e-20
 Identities = 59/179 (32%), Positives = 89/179 (49%), Gaps = 7/179 (3%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   PD  K          T          +  L+AAL+ ERRV +  S+   +S  V A
Sbjct: 179 TLTAPDLKK--EFNGGIKFTSLLDCGHVDAVLALFAALVTERRVVLTGSRLEFVSGAVHA 236

Query: 165 ANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDAN 224
           ANA L+P+SWQHIF+P+LP+  +DY+ APMPFLIG+  S++  ++     D+  LD+D  
Sbjct: 237 ANAALYPLSWQHIFLPVLPEGFLDYLTAPMPFLIGLHSSLVSVMKRLPCDDIFTLDLDTG 296

Query: 225 ELRSPFNDLETLPPELISSLKKAL-----SDKNALGDAVSRAFLRALVCLIGGYRDAIK 278
           E      DL ++P    + L+  L       +     AV++ F      ++G Y+  IK
Sbjct: 297 EFTYFDEDLRSMPAGPFTLLRVGLLREMEKSRGQDSQAVAQVFRTFFSSVLGQYKQHIK 355


>UniRef50_Q5U3I4 Cluster: Zgc:103487; n=4; Danio rerio|Rep:
           Zgc:103487 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 488

 Score =  101 bits (242), Expect = 3e-20
 Identities = 77/260 (29%), Positives = 132/260 (50%), Gaps = 23/260 (8%)

Query: 75  LHSFLEACRIRP-PMPGHTLKV---IYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAV 130
           ++ F+++ R  P P PG T+ +   I +AG  +     P  + L    ++ + T  FS +
Sbjct: 199 IYPFMQSLREAPLPSPGSTVSISSFIPDAGTQIIRLTRPADSWL----EHVDFTALFSRL 254

Query: 131 DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
           + + +  ++ A + ERR+  ++ + S LS  + A  A L+P  WQH FI I+P  L+D  
Sbjct: 255 NDEELLLVFTAAVLERRIIFISEELSTLSQVLHAVAALLYPFVWQHTFISIVPSVLIDVC 314

Query: 191 LAPMPFLIGVPRSVMENVRMSEIGDVVILDVDA---NELRSPFNDLETLPP-----ELIS 242
            AP P+L+GV +S+M  +  ++  DV+I+D+      +  +   D E+L P     EL+S
Sbjct: 315 EAPTPYLLGVQKSMMGLI--TDHSDVMIVDLSTGAPTKFITRIGDEESLLPLKLKEELLS 372

Query: 243 SLKKAL--SDKNALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT--RKN 298
            L      +    L   VS AFL   V  +G + + IK   G+   F  ++F+K    K 
Sbjct: 373 GLSARTHHASTEQLNRLVSEAFLSVFVKTVGHFSEHIK-RGGKPRQFQKKSFLKAVENKT 431

Query: 299 MQPFLRKILQSQIFQQFIDE 318
              F++  +Q+Q+F  FI E
Sbjct: 432 YSSFVKLFIQTQMFDLFIQE 451


>UniRef50_Q9H6A0 Cluster: DENN domain-containing protein 2D; n=29;
           Euteleostomi|Rep: DENN domain-containing protein 2D -
           Homo sapiens (Human)
          Length = 471

 Score = 98.7 bits (235), Expect = 2e-19
 Identities = 64/203 (31%), Positives = 114/203 (56%), Gaps = 12/203 (5%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           ++A+ + ER++  +A   S LS C+ AA A L+P SW H +IP++P+ L+  +  P PF+
Sbjct: 247 IFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFM 306

Query: 198 IGVPRSVMENVRMSEIGDVVILDV-DANELRSPFNDLETLPPEL----ISSLKKALSD-K 251
           +GV     + V  S + +V+++++ +   L S  ++ + LPP+L    + SL + +++ K
Sbjct: 307 VGVQMRFQQEVMDSPMEEVLLVNLCEGTFLMSVGDEKDILPPKLQDDILDSLGQGINELK 366

Query: 252 NA--LGDAVSRAFLRALVCLIGGYRDAIKIE-NGQLITFNPEAFVK--TRKNMQPFLRKI 306
            A  + + VS  F++  V ++G Y   IK E NGQ   F   +F K  T K  + F++K 
Sbjct: 367 TAEQINEHVSGPFVQFFVKIVGHYASYIKREANGQ-GHFQERSFCKALTSKTNRRFVKKF 425

Query: 307 LQSQIFQQFIDERLDLLNSGRGF 329
           +++Q+F  FI E     N   G+
Sbjct: 426 VKTQLFSLFIQEAEKSKNPPAGY 448


>UniRef50_UPI0000F1E8B0 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 729

 Score = 92.3 bits (219), Expect = 2e-17
 Identities = 80/290 (27%), Positives = 137/290 (47%), Gaps = 32/290 (11%)

Query: 75  LHSFLEACRIRPPMPGHTLKV---IYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVD 131
           +HS +EA     P PG T+ V   +  +G+ V T   P  ++L    ++ +       + 
Sbjct: 423 MHSVMEAPF---PAPGRTITVKSFLPGSGNEVLTLCRPVDSRL----EHVDFESLLQCLS 475

Query: 132 TKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYML 191
              +  ++A+L+ ERRV  +A K S LS C  +A A L+P +WQH F+P+LP  ++D   
Sbjct: 476 VSRLLQVFASLMLERRVIFIADKLSVLSRCAHSALALLYPFTWQHTFVPVLPAGMLDICC 535

Query: 192 APMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLE-TLPPELISSLKKAL-- 248
           +P PF++G     +  V    I +V+I+D+  ++      D +  LP +L ++L++ L  
Sbjct: 536 SPTPFVMGALSPSLPEVLDMPIEEVLIVDLCTDKFVVQLGDEDCILPSKLQAALQEILEN 595

Query: 249 -------------SDKNALGDAVSRAFLRALVCLIGGYRDAIKIEN-GQLITFNPEAFVK 294
                         DK+ L   VS AF+   V ++G Y   +     G       +AF K
Sbjct: 596 REEILEQNRRDRRGDKSDLSTLVSEAFVWFFVEIVGHYSLYMNDSGPGGTRELQRDAFRK 655

Query: 295 TR--KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYAD 342
           +   + ++  L+  + +Q+F  FI +R   L  G G    FE+    Y D
Sbjct: 656 SHPSRGVRQLLQLFMDTQMFAGFIQDR--ELRKG-GVKGLFELRAAEYLD 702


>UniRef50_UPI0000D571A2 Cluster: PREDICTED: similar to suppression
           of tumorigenicity 5; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to suppression of tumorigenicity 5 -
           Tribolium castaneum
          Length = 527

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 64/217 (29%), Positives = 113/217 (52%), Gaps = 23/217 (10%)

Query: 132 TKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYML 191
           T+ +  ++A+LL ER+V +++   S+LS CV A  + L+P SW H FIPILP+ L D + 
Sbjct: 302 TEILLRIFASLLLERKVVLISCVISKLSCCVDALQSILYPFSWPHTFIPILPQCLWDVVE 361

Query: 192 APMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDK 251
           +P P + G+    + N    E G  +++D+D   + S   D +++   L  S+KKA +  
Sbjct: 362 SPTPVICGILSVAIVNDHKIENG--IVVDLDTGNIMSEEGDEDSI---LSDSMKKAWNQS 416

Query: 252 NALGDAV-----------SRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT--RKN 298
            AL + V           S A+++  +  +  Y++ I  +N     F  EAFV+    K 
Sbjct: 417 IALANTVPKEDYVHSVYLSDAYIKVFIVSLKHYKNHIVGKN-----FEKEAFVRNGKTKG 471

Query: 299 MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEV 335
           ++ FL+   ++ +F  FID  +   +S   F+ + E+
Sbjct: 472 IRRFLKWFTETSMFVSFIDMVISNPDSFTLFDKKIEM 508


>UniRef50_UPI00015B4FAB Cluster: PREDICTED: similar to myotubularin;
           n=2; Apocrita|Rep: PREDICTED: similar to myotubularin -
           Nasonia vitripennis
          Length = 2064

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 77/261 (29%), Positives = 120/261 (45%), Gaps = 32/261 (12%)

Query: 86  PPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHE 145
           PP  G  ++    AG      Q P S  LP    + NL   F  +  + +  L+ A++ E
Sbjct: 191 PPAGGPQVRFSIGAGDRQ-ALQPPISPSLPITHTSVNLL--FQQLGIRNVLVLFCAVMTE 247

Query: 146 RRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVM 205
            ++   ++  SRL+   +A  A ++P  + H++IP+LP  LV+ +  P PF++GV  S+ 
Sbjct: 248 HKILFHSASYSRLTEGCRALTALMYPFRYTHVYIPLLPAALVEVLSTPTPFIMGVHSSLK 307

Query: 206 ENVRMSEIGDVVILDVDANELRSPFN-DLETLPPELISSLKKALS----DKNALGD---- 256
             V  +E+ DV++ D+D   +  P    L  LP  L+S  + ALS     + A  D    
Sbjct: 308 YEV--AELMDVIVADLDGGSIMVPDGVSLPLLPEPLLSQTQDALSLVLQPELACADYAFP 365

Query: 257 -AVSRA-------------FLRALVCLIGGYRDA---IKIENGQLITFNPEAFVKTRKNM 299
              SRA             F+R    L+ GYR     I+I    +ITF+  AF+  R  M
Sbjct: 366 PMASRAPNPAMLDKELRAVFMRTFANLLQGYRSCLTLIRIHPKPVITFHKAAFLGERNLM 425

Query: 300 Q-PFLRKILQSQIFQQFIDER 319
              F  ++L    F  FI ER
Sbjct: 426 DCDFTVRVLDCMFFTSFIAER 446


>UniRef50_Q1L8F0 Cluster: Novel protein; n=6; Clupeocephala|Rep:
           Novel protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 454

 Score = 84.2 bits (199), Expect = 5e-15
 Identities = 53/142 (37%), Positives = 77/142 (54%), Gaps = 10/142 (7%)

Query: 241 ISSLKKALSDKN-ALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKN- 298
           +SSLK  L  ++ A G  V+RAFL A   L G YRDA++ + G+ ITF  ++FV  R + 
Sbjct: 1   VSSLKSKLKKQSTATGAGVARAFLHAQAALFGSYRDALRYKPGEPITFCEKSFVAHRSSA 60

Query: 299 MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQQYRD 358
           M+ FL   +  Q+F+QFI+ RL  LN+GRGF D +E E          G  +   + Y+ 
Sbjct: 61  MRGFLEMAVNLQLFKQFIEGRLAKLNAGRGFTDVYEEEIT------EGGFCKSNSKSYQQ 114

Query: 359 W--AKTVKKEGGAFFKTVKDKV 378
           W   K  K       + +KDK+
Sbjct: 115 WIHTKMAKDHAKRKIRDMKDKI 136


>UniRef50_UPI0000DB6D52 Cluster: PREDICTED: similar to SET domain
           binding factor CG6939-PB, isoform B isoform 1; n=3;
           Endopterygota|Rep: PREDICTED: similar to SET domain
           binding factor CG6939-PB, isoform B isoform 1 - Apis
           mellifera
          Length = 2007

 Score = 83.4 bits (197), Expect = 9e-15
 Identities = 74/261 (28%), Positives = 118/261 (45%), Gaps = 32/261 (12%)

Query: 86  PPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHE 145
           PP  G  ++    AG      Q P S  LP    + NL   F  +  + +  L+ A++ E
Sbjct: 174 PPAGGPQVRFSIGAGDRQ-ALQPPISPSLPITHSSVNLL--FQQLGIRNVLVLFCAVMTE 230

Query: 146 RRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVM 205
            ++   ++  SRL+   +A  A ++P  + H++IP+LP  LV+ +  P PF++GV  S+ 
Sbjct: 231 HKILFHSASYSRLTEGCRALTALMYPFRYTHVYIPLLPAALVEVLSTPTPFIMGVHSSLK 290

Query: 206 ENVRMSEIGDVVILDVDANELRSPFN-DLETLPPELISSLKKALS--------------- 249
             V  +E+ DV++ D+D   +  P    L  LP  L+S  + ALS               
Sbjct: 291 HEV--TELMDVIVADLDGGSIMVPDGVSLSLLPEPLLSQTQDALSLVLQPELSCADYAFP 348

Query: 250 ------DKNALGDAVSRA-FLRALVCLIGGYRDA---IKIENGQLITFNPEAFVKTRKNM 299
                   + + D   RA F+R    L+ GYR     I+I    +ITF+  AF+  R   
Sbjct: 349 PLATRAPHSPMLDKELRAVFMRTFAQLLQGYRSCLTLIRIHPKPVITFHKAAFLGERGLT 408

Query: 300 Q-PFLRKILQSQIFQQFIDER 319
              F  ++L    F  FI ER
Sbjct: 409 DCDFTTRVLDCMFFTSFIAER 429


>UniRef50_UPI00006A2097 Cluster: DENN domain-containing protein 1A.;
           n=2; Xenopus tropicalis|Rep: DENN domain-containing
           protein 1A. - Xenopus tropicalis
          Length = 644

 Score = 80.2 bits (189), Expect = 8e-14
 Identities = 43/94 (45%), Positives = 57/94 (60%), Gaps = 8/94 (8%)

Query: 285 ITFNPEAFVKTRKN-MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADK 343
           ITF  E FV  R + ++PFL+  +Q Q+F+QFID RLDLLNSG GF+D FE       ++
Sbjct: 3   ITFCEETFVSHRSSGLRPFLQNAIQLQLFKQFIDGRLDLLNSGNGFSDVFE-------EE 55

Query: 344 LNTGSGQKLKQQYRDWAKTVKKEGGAFFKTVKDK 377
           +N G      + Y  W  TVKK  GAF  T+K +
Sbjct: 56  INMGEYAGSDKLYHQWLSTVKKGSGAFINTMKTR 89


>UniRef50_Q6NZD6 Cluster: Dennd2c protein; n=4; Euteleostomi|Rep:
           Dennd2c protein - Mus musculus (Mouse)
          Length = 283

 Score = 78.2 bits (184), Expect = 3e-13
 Identities = 56/180 (31%), Positives = 89/180 (49%), Gaps = 16/180 (8%)

Query: 32  FKYPESYKNEEEIKSIPKFTFPCSLEKLLNCIANIINSPERDQ------LHSFLEACRIR 85
           F Y +    E   K +P+     S     N  + I++  E+ +      ++ F+ +    
Sbjct: 72  FGYCKKLLPEGRGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEA 131

Query: 86  P-PMPGHTLKV---IYNAG-HSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWA 140
           P P PG T+ V   +  AG  S+  C+  DS +L  +   C     F  +  + +  + A
Sbjct: 132 PFPAPGRTITVKSYLPGAGDESIELCRPLDS-RLEHVDFEC----LFKCLSVRHLIRVCA 186

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           +LL ERRV  VA+  S LS C  A  ATL+P +WQH +IP+LP  ++D + +P PF IG+
Sbjct: 187 SLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPVSMIDIVCSPTPFFIGI 246


>UniRef50_Q4S7I6 Cluster: Chromosome 13 SCAF14715, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
           SCAF14715, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1282

 Score = 76.6 bits (180), Expect = 1e-12
 Identities = 53/198 (26%), Positives = 91/198 (45%), Gaps = 10/198 (5%)

Query: 56  LEKLLNCIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLP 115
           L +L   +A+  +SP    L S++       P+P     + ++       CQ P   +LP
Sbjct: 237 LSQLHQAVAS--HSPPPLPLESYIHNILYEVPLPPPGRSLRFHGVQGPIVCQRPGPGELP 294

Query: 116 SIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQ 175
                  L E FS +  + M  L    L E ++ + +    RL    ++    LFP  WQ
Sbjct: 295 M--GEYPLGEAFSLLGVENMVKLLTCTLLETQILLYSQDYQRLMTVSESVTTLLFPFQWQ 352

Query: 176 HIFIPILPKHLVDYMLAPMPFLIGVPR---SVMENVRMSEIGDVVILDVDANELRSPFND 232
           HI++PI+  HL   + AP+PFL+G+ R   +   ++ +    ++  +D+D + + +P  D
Sbjct: 353 HIYLPIVSAHLYHLLDAPVPFLMGIQRRDGAQRSSLHLPHEANLCFVDIDNHCVEAP-ED 411

Query: 233 LETLP--PELISSLKKAL 248
           L   P   ELI  L + L
Sbjct: 412 LPVFPEQTELIQELSEVL 429


>UniRef50_Q8BJD2 Cluster: 0 day neonate eyeball cDNA, RIKEN
           full-length enriched library, clone:E130006I02
           product:KIAA1766 PROTEIN homolog; n=5; cellular
           organisms|Rep: 0 day neonate eyeball cDNA, RIKEN
           full-length enriched library, clone:E130006I02
           product:KIAA1766 PROTEIN homolog - Mus musculus (Mouse)
          Length = 715

 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 74/265 (27%), Positives = 117/265 (44%), Gaps = 31/265 (11%)

Query: 82  CRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAA 141
           C    P  G + K+           Q P  + LP    +  L   F  +  + +  L+ A
Sbjct: 160 CACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALL--FQQLGIQNVLNLFCA 217

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           +L E +V   ++   RLS   +A  + +FP+ + + +IPILP  L++ + +P PF+IGV 
Sbjct: 218 VLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGV- 276

Query: 202 RSVMENVRMSEIGDVVILDVDANELRSP-FNDLETLPPELI----SSL------------ 244
            S+ +   + E+ DV+I D+D    + P    L +LP  L+    S+L            
Sbjct: 277 HSIFK-TDVHELLDVIIADLDGGTFKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVAD 335

Query: 245 ------KKALSDKNALGDAVSRAFLRALVCLIGGYRDA---IKIENGQLITFNPEAFVKT 295
                 + ALS    L   V   FLR    L  GYR     I+I    +I F+  AF+  
Sbjct: 336 HAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQ 395

Query: 296 RKNMQ-PFLRKILQSQIFQQFIDER 319
           R  ++  FL K+L    F  F+ ER
Sbjct: 396 RGLVENDFLTKVLNGMAFAGFVSER 420


>UniRef50_UPI000049A2A5 Cluster: DENN domain protein; n=3; Entamoeba
           histolytica HM-1:IMSS|Rep: DENN domain protein -
           Entamoeba histolytica HM-1:IMSS
          Length = 991

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 46/145 (31%), Positives = 78/145 (53%), Gaps = 5/145 (3%)

Query: 107 QCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAAN 166
           Q P  N LP IP +  +   F  +    +  +W ALL E +V I ++  + L   ++   
Sbjct: 400 QLPCLNGLPPIPTS--ILPLFEMIGIDGVLAVWLALLEEEKVIITSTSKTALVYSIENLK 457

Query: 167 ATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENV-RMSEIGDVVILDVDANE 225
           + LFP  W +I I  LP  L+DY+ +PM +L+GVP    E+V ++ +  +VV +D+D+  
Sbjct: 458 SLLFPFEWCNICIDSLPYSLIDYVSSPMTYLMGVPSEYKEDVEKIIKNEEVVYVDLDSGV 517

Query: 226 LRSPFNDLETLPPELISSLKKALSD 250
           ++S     E   P+LI+++   L D
Sbjct: 518 VKSKGIIREV--PKLINTVYHELKD 540


>UniRef50_A0DVL5 Cluster: Chromosome undetermined scaffold_66, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_66,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 915

 Score = 75.8 bits (178), Expect = 2e-12
 Identities = 71/258 (27%), Positives = 121/258 (46%), Gaps = 31/258 (12%)

Query: 84  IRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           + P  P  T   IYN    +F  Q   SN  P +  N      F+ ++ K +  L+ ALL
Sbjct: 299 VLPQDPAETY--IYNGAKQIFFFQ---SNCFP-LCSNQAFQCLFAVLNKKNIVLLYFALL 352

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRS 203
           +E+++ +++SKP   S  ++A    L+P  + HI I  LP+ L  Y+ AP+P+LIG+ + 
Sbjct: 353 YEKKIQLISSKPVISSLVIEALLTLLYPFEFTHILISNLPEDLEQYLEAPLPYLIGINKK 412

Query: 204 VME-------------NVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKAL-- 248
             E             N++ S+  DV     D   L+    D +   P LI ++  A   
Sbjct: 413 QAEKYPDAIQVFLDSNNIKQSQTIDVPEDIFDKFVLKLKEFD-KYYNPGLIETIGDAFPM 471

Query: 249 --SDKNALGD--AVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQPFLR 304
              D+  + D   V   FLR  + L+  Y+  I  +      F  + FVK+++ ++ FL 
Sbjct: 472 PREDELEMIDQYQVREVFLRFNIFLLQDYKKFIDKQ-----VFKEKLFVKSKQRIKQFLE 526

Query: 305 KILQSQIFQQFIDERLDL 322
             +++++F  FI  R+ L
Sbjct: 527 PFMETRLFTFFIQVRMQL 544


>UniRef50_Q6IQ26 Cluster: Rab6-interacting protein 1; n=59;
           Eumetazoa|Rep: Rab6-interacting protein 1 - Homo sapiens
           (Human)
          Length = 1287

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 41/157 (26%), Positives = 83/157 (52%), Gaps = 8/157 (5%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P PG +LK  ++  +    CQ P +N+LP    +  + E F  +  + +  L+   L E 
Sbjct: 254 PPPGRSLK--FSGVYGPIICQRPSTNELPLF--DFPVKEVFELLGVENVFQLFTCALLEF 309

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           ++ + +    RL    +   A +FP  WQH+++PILP  L+ ++ AP+P+L+G+  + ++
Sbjct: 310 QILLYSQHYQRLMTVAETITALMFPFQWQHVYVPILPASLLHFLDAPVPYLMGLHSNGLD 369

Query: 207 N---VRMSEIGDVVILDVDANELRSPFNDLETLPPEL 240
           +   + + +  ++  +D+D + +  P  DL   P +L
Sbjct: 370 DRSKLELPQEANLCFVDIDNHFIELP-EDLPQFPNKL 405


>UniRef50_Q54JL9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1864

 Score = 74.9 bits (176), Expect = 3e-12
 Identities = 39/128 (30%), Positives = 72/128 (56%), Gaps = 4/128 (3%)

Query: 112 NKLPSIPD-NCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLF 170
           + LP  P  +   +  F+ +       L++A+L ER+V  ++   S L+   +     L+
Sbjct: 250 SNLPLFPSLDIPFSLLFNIIGVNNTINLFSAVLQERKVLFLSKFNSLLTIVCETLIGLLY 309

Query: 171 PMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS-P 229
           P SW H++IPILP  LVD++ AP PF++G+ ++  +N    ++ D+V++D+D  ++ S P
Sbjct: 310 PFSWPHVYIPILPDLLVDFLQAPTPFIVGMIKN--KNQPKIDLSDIVVVDLDLQQIVSKP 367

Query: 230 FNDLETLP 237
              +  LP
Sbjct: 368 DGFINNLP 375


>UniRef50_UPI0000499496 Cluster: hypothetical protein 153.t00003;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 153.t00003 - Entamoeba histolytica HM-1:IMSS
          Length = 665

 Score = 74.5 bits (175), Expect = 4e-12
 Identities = 58/210 (27%), Positives = 94/210 (44%), Gaps = 8/210 (3%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           +L E R    +  P  +   +QA    L P  WQHI IPILP  L  Y+ + +P +IG  
Sbjct: 171 MLLEERFIFHSCTPETIHPTIQAFLNVLQPFVWQHILIPILPLFLSSYLSSILPCIIGCT 230

Query: 202 RSVMENVRM--SEIGDVVILDVDANELRSPF---NDLETLPPEL-ISSLKKALSDKNALG 255
           R    N  M   E  DV ++D+D ++  S     N L  +P  + ++ L   ++++    
Sbjct: 231 RGTYANFMMEFGEDDDVHVIDIDKHQEVSRCIRENYLVNMPMGIFMARLDFIIANEQEFN 290

Query: 256 DA-VSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQPFLRKILQSQIFQQ 314
           D  V + F +    ++  +    K +N     F  E F+ +  + + FL+   QSQ+F Q
Sbjct: 291 DEDVVKLFKQLYKLMLERHSHFFK-KNESKFEFAQEMFLSSTSSFKEFLKHFSQSQMFFQ 349

Query: 315 FIDERLDLLNSGRGFNDEFEVECNAYADKL 344
           FI+E  + LN     +      C     KL
Sbjct: 350 FIEEETNKLNHNLPISPIINETCTVRYRKL 379


>UniRef50_A2G0S6 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 1081

 Score = 74.1 bits (174), Expect = 6e-12
 Identities = 36/119 (30%), Positives = 66/119 (55%), Gaps = 2/119 (1%)

Query: 135 MAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPM 194
           +  L A +  + ++ I A+  +RLS    +  + ++P++W  +FIP+LP  L D +LAP 
Sbjct: 161 VGNLIAYIAADSKIIIQATSLTRLSKVCFSLISLIYPLNWPGVFIPLLPAKLTDAILAPF 220

Query: 195 PFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNA 253
           PF+IG+P ++  NV   ++   + LDVD    +  F  +  LP ++ S++K      N+
Sbjct: 221 PFIIGIPAALASNVSWEDVESHIFLDVDTGTCK--FRGVPELPKQVKSNVKSFAKSINS 277


>UniRef50_Q55FT6 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 844

 Score = 73.7 bits (173), Expect = 7e-12
 Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 6/128 (4%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F+ +   C+  + +A+L E+RV  V    S LS+C  +  + + P+ WQ +F+PILP++L
Sbjct: 569 FANLSLDCILRVLSAVLLEQRVVFVCDNLSILSSCCFSMISLIHPLKWQGLFVPILPQNL 628

Query: 187 VDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKK 246
           +DY+ AP+PF++GV      N       D +I+D+ +N++         + PE    L  
Sbjct: 629 LDYLEAPVPFIVGVSHINRRNF------DGLIVDIKSNKITYNRCSQPPIIPEFNKLLNN 682

Query: 247 ALSDKNAL 254
             +D N L
Sbjct: 683 LKNDTNTL 690


>UniRef50_UPI0000498ADA Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 364

 Score = 72.1 bits (169), Expect = 2e-11
 Identities = 49/202 (24%), Positives = 100/202 (49%), Gaps = 10/202 (4%)

Query: 126 YFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKH 185
           + S +    +  L+A++L+ERRV ++   PS  S  V      L P  WQHI I  LP  
Sbjct: 146 FLSKISENTLRCLFASILNERRVVVIGQNPSEFSVVVLLLLEILIPFEWQHIIITHLPVS 205

Query: 186 LVDYMLAPMPFLIGVPRSVMENVRMS-EIGDVVILDVDANELRSPFNDLETLPPE----L 240
           +V  + +P+PF+IG+  +    V     + ++  L V A +++    D+++ P      L
Sbjct: 206 MVSLLQSPLPFIIGMKTNEFIQVSNEVVVFNIDTLTVQATDIKLVQTDIDSFPIRSFNIL 265

Query: 241 ISSLKKALS-DKNALGDAVSRAFLRALVCLIGGYRDAIKI-ENGQLIT--FNPEAFVK-T 295
             S+K +++ +K    +A+  AF   L  +       I + EN   +   F+   + + +
Sbjct: 266 YESIKHSITLEKREQRNAIKSAFNLFLFPIYSQVNKYIILQENLNTLDAYFDEHLYFRHS 325

Query: 296 RKNMQPFLRKILQSQIFQQFID 317
            ++++ FL+  +++ + QQ+++
Sbjct: 326 NEDIKQFLKTFMKTTLMQQYVE 347


>UniRef50_Q54VP0 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 2176

 Score = 71.7 bits (168), Expect = 3e-11
 Identities = 52/188 (27%), Positives = 92/188 (48%), Gaps = 10/188 (5%)

Query: 69   SPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFS 128
            SP   + + F     I+ P PG         G +    + PD   LP  PD  +    F 
Sbjct: 941  SPIPIERYIFNLVSEIQLPRPGKNPVTFSLGGLNQCLLKQPDPCLLPE-PD-ISYRMLFL 998

Query: 129  AVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVD 188
            ++D + +  L   LL E ++ I++S+ + L+   +     + P+ + HI++P+LP+ LVD
Sbjct: 999  SLDIRNVLSLIKCLLLEEKILIISSQYTLLTYICEIITTLIHPLVYTHIYVPVLPEVLVD 1058

Query: 189  YM-LAPMPFLIGVPRSVMENVRMSE--IGDVVILDVDANELRSPFNDLETLPPE-----L 240
                 P PF++G+ RS  + +   E  + ++VI+D+D N +  P +  +   PE     L
Sbjct: 1059 IAGSTPFPFIMGIHRSYADRILSKEDLLNELVIVDLDNNSINIPTSTKDIQLPEKETQIL 1118

Query: 241  ISSLKKAL 248
            I+ LKK +
Sbjct: 1119 INQLKKVV 1126


>UniRef50_Q55DD7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1342

 Score = 70.9 bits (166), Expect = 5e-11
 Identities = 57/227 (25%), Positives = 103/227 (45%), Gaps = 11/227 (4%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+   + E RV +++   S +S  + A ++ L P+ WQHIFI ILP  L+ Y+ AP+PFL
Sbjct: 208 LFEFAITESRVILLSKDISVVSNGILALSSLLSPLVWQHIFISILPNALMPYVAAPIPFL 267

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSD------- 250
           +G+  S +++        V++ ++D  +     +    LP  +   L   L +       
Sbjct: 268 VGILESSLKSFYQQPTEQVILYNLDTLDFIIDPDTKSLLPYHIRIYLDNYLKEFKTQHPT 327

Query: 251 -KNALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQ--PFLRKIL 307
             N     + + F   +  L   Y +   +++G   +F  + F+++  N Q    L  I 
Sbjct: 328 YNNDFDSEIRKPFYSVIYHLFQHYSN-FMLKSGANYSFFKDQFLESPLNSQNKKLLEVIC 386

Query: 308 QSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQ 354
            SQ+ + F  E+ +  +     N EF       AD++   S +KL Q
Sbjct: 387 NSQMVEVFFGEKENEFSDSGEVNCEFLNGAREKADEIPFFSRKKLGQ 433


>UniRef50_Q6NTN5 Cluster: Myotubularin-related protein 13; n=7;
           Euteleostomi|Rep: Myotubularin-related protein 13 -
           Xenopus laevis (African clawed frog)
          Length = 1873

 Score = 70.9 bits (166), Expect = 5e-11
 Identities = 75/274 (27%), Positives = 120/274 (43%), Gaps = 33/274 (12%)

Query: 73  DQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDT 132
           + L S L  C +  P  G + K+           Q P  + LP    +  L   F  +  
Sbjct: 152 ENLVSNLVTCIV--PCAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALL--FQQLGI 207

Query: 133 KCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLA 192
           + +  L+ A+L E +V   +S   RL    +A  A ++P+ + + +IPILP  L++ + +
Sbjct: 208 QNVLSLFCAVLTENKVLFHSSSFQRLGDACRALEALIYPLKYSYPYIPILPAQLLEVLSS 267

Query: 193 PMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSP-FNDLETLPPELISSLKKALS-- 249
           P PF+IGV  SV  +  + ++ DV+I D+D   ++ P    L  +P  L+   + ALS  
Sbjct: 268 PTPFIIGV-HSVFCS-EIHDLLDVIIADLDGGTIKIPECIHLSPIPEPLLHQTQAALSLV 325

Query: 250 -------DKNA-------------LGDAVSRAFLRALVCLIGGYRDA---IKIENGQLIT 286
                    NA             L   V   FLR    +  GYR     I+I    +I 
Sbjct: 326 LHPDLEVADNAFAPLRTPVPHIKLLDKEVRAVFLRLFAQIFQGYRSCLQLIRIHAEPIIH 385

Query: 287 FNPEAFVKTRKNMQ-PFLRKILQSQIFQQFIDER 319
           F+  AF+  R  ++  FL K+L    F  F+ ER
Sbjct: 386 FHKAAFLGQRGLIENDFLTKVLSGMSFAGFVSER 419


>UniRef50_Q7PWX7 Cluster: ENSANGP00000020490; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000020490 - Anopheles gambiae
           str. PEST
          Length = 1643

 Score = 70.1 bits (164), Expect = 9e-11
 Identities = 65/241 (26%), Positives = 112/241 (46%), Gaps = 42/241 (17%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           +L E+++ I + +P+ L+A  +A ++ LFP  WQ  +IP+ P  L + + AP+P+LIGV 
Sbjct: 415 VLTEQKLLIHSLRPAILTAVAEAVSSFLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVD 474

Query: 202 RSVMENVRMSEIGDVVILDVDANE----------------------LRSPFNDLETLPP- 238
               +        DV  +D+D N                       LR    +LE +   
Sbjct: 475 SRFFD--LYEPPNDVTCVDLDTNNISLCESQKHLTTKLLPKRAARVLRQTLRNLEEMSQN 532

Query: 239 ---ELISSLKKALSDKNA---LGDAVSRAFLRALVCLIGGYRD-AIKIENGQLI------ 285
              +  +SL + L  +     L   +  AFL+ + C + GYRD  + I     I      
Sbjct: 533 HGCDSSNSLDRDLKKRKREQNLEQRIQEAFLQFMACTLKGYRDYLVPISKAPTIGATDPS 592

Query: 286 -TFNPEAFVKTR-KNMQPFLRKILQSQIFQQFIDERLDLLNSGR--GFNDEFEVECNAYA 341
             F  +AF+++R K    F + ++++Q+F +FI+ER  + +S     F DE   + +AY 
Sbjct: 593 ALFRMDAFLRSRDKTNHKFFQLLMKTQMFIRFIEERSFVSDSDHNLAFFDECAEKVSAYE 652

Query: 342 D 342
           D
Sbjct: 653 D 653


>UniRef50_A6PVG9 Cluster: SET binding factor 1; n=28;
           Euteleostomi|Rep: SET binding factor 1 - Homo sapiens
           (Human)
          Length = 1893

 Score = 70.1 bits (164), Expect = 9e-11
 Identities = 67/260 (25%), Positives = 110/260 (42%), Gaps = 31/260 (11%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P+ G + + I          Q P ++ LP     C++   F  +    +  L+ A L E 
Sbjct: 177 PLAGGSQRTISLGAGDRQVIQTPLADSLPV--SRCSVALLFRQLGITNVLSLFCAALTEH 234

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           +V  ++    RL+   +   A LFP+ +   ++PILP  L++ +  P PF+IGV  +   
Sbjct: 235 KVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQA 294

Query: 207 NVRMSEIGDVVILDVDANELRSP-FNDLETLPPELISSLKKALS---------------- 249
             +  E+ DV++ D+D   +  P    +  LP  L S     LS                
Sbjct: 295 ETQ--ELLDVIVADLDGGTVTIPECVHIPPLPEPLQSQTHSVLSMVLDPELELADLAFPP 352

Query: 250 -----DKNALGDAVSRA-FLRALVCLIGGYR---DAIKIENGQLITFNPEAFVKTRKNMQ 300
                    + D   RA FLR    L+ GYR     ++I    +I F+  AF+  R  ++
Sbjct: 353 PTTSTSSLKMQDKELRAVFLRLFAQLLQGYRWCLHVVRIHPEPVIRFHKAAFLGQRGLVE 412

Query: 301 -PFLRKILQSQIFQQFIDER 319
             FL K+L+   F  F+ ER
Sbjct: 413 DDFLMKVLEGMAFAGFVSER 432


>UniRef50_O95248 Cluster: Myotubularin-related protein 5; n=55;
           Deuterostomia|Rep: Myotubularin-related protein 5 - Homo
           sapiens (Human)
          Length = 1867

 Score = 70.1 bits (164), Expect = 9e-11
 Identities = 67/260 (25%), Positives = 110/260 (42%), Gaps = 31/260 (11%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P+ G + + I          Q P ++ LP     C++   F  +    +  L+ A L E 
Sbjct: 177 PLAGGSQRTISLGAGDRQVIQTPLADSLPV--SRCSVALLFRQLGITNVLSLFCAALTEH 234

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           +V  ++    RL+   +   A LFP+ +   ++PILP  L++ +  P PF+IGV  +   
Sbjct: 235 KVLFLSRSYQRLADACRGLLALLFPLRYSFTYVPILPAQLLEVLSTPTPFIIGVNAAFQA 294

Query: 207 NVRMSEIGDVVILDVDANELRSP-FNDLETLPPELISSLKKALS---------------- 249
             +  E+ DV++ D+D   +  P    +  LP  L S     LS                
Sbjct: 295 ETQ--ELLDVIVADLDGGTVTIPECVHIPPLPEPLQSQTHSVLSMVLDPELELADLAFPP 352

Query: 250 -----DKNALGDAVSRA-FLRALVCLIGGYR---DAIKIENGQLITFNPEAFVKTRKNMQ 300
                    + D   RA FLR    L+ GYR     ++I    +I F+  AF+  R  ++
Sbjct: 353 PTTSTSSLKMQDKELRAVFLRLFAQLLQGYRWCLHVVRIHPEPVIRFHKAAFLGQRGLVE 412

Query: 301 -PFLRKILQSQIFQQFIDER 319
             FL K+L+   F  F+ ER
Sbjct: 413 DDFLMKVLEGMAFAGFVSER 432


>UniRef50_UPI000049A4AE Cluster: hypothetical protein 675.t00001;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 675.t00001 - Entamoeba histolytica HM-1:IMSS
          Length = 359

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 50/196 (25%), Positives = 92/196 (46%), Gaps = 17/196 (8%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L++++L+ERR+ I ++   ++S  + +      P+ WQH+ +P LP    +    P PF+
Sbjct: 155 LFSSILNERRIIIQSNSAQKISEFIVSLLEIFSPLKWQHLLVPFLPIKYTELTETPTPFI 214

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSP-----FNDLETLPPELISS----LKKAL 248
           IGV  S+ME + + +I  +V +D+D   ++S       +D E +P + I+S    LK   
Sbjct: 215 IGVDPSIMEIIDLFDI--IVFVDIDKGIIKSTDSTIIKSDYELIPSKWINSITNTLKPIY 272

Query: 249 SDKNALGD---AVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKT---RKNMQPF 302
           S    + D    + +AF   + C I      I+        +N + F K        + F
Sbjct: 273 SHSETIDDKNIIIKKAFNELMNCFIKDIEIRIRSMIETNTEYNVKEFYKDYFFLGEERKF 332

Query: 303 LRKILQSQIFQQFIDE 318
           +    ++  F QF+ E
Sbjct: 333 IEMFSKTAAFDQFVLE 348


>UniRef50_Q7Q9J0 Cluster: ENSANGP00000010428; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000010428 - Anopheles gambiae
           str. PEST
          Length = 332

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 55/209 (26%), Positives = 94/209 (44%), Gaps = 13/209 (6%)

Query: 119 DNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIF 178
           +   L + F  + +  +  ++ +LL E+ V + +   S L++CVQ     L+P  WQHI 
Sbjct: 127 EKTELYDIFKCLGSDGLIHVFESLLLEKMVILFSEHLSLLTSCVQGLLLILYPFQWQHIL 186

Query: 179 IPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFND-LETLP 237
           +  +P+HL   + AP+P L G  + V E   + E G+   +++D   +R    +    LP
Sbjct: 187 VTAIPEHLQQMLEAPVPMLAGTLQPVPE--ELWETGNTCYVNLDKRTVRPARKEQFSILP 244

Query: 238 PELISSLK------KALSDKNALGDA-VSRAFLRALVCLIGGYRDAIKIENGQLITFNPE 290
            EL   L+      K   D   L    +  AF+R  V L     D    E          
Sbjct: 245 SELKKPLRVSLDLVKIFEDSKGLASVLIGGAFVRFFVELFSTL-DPHTYEVSAQFVGGKA 303

Query: 291 AFVKTRKN--MQPFLRKILQSQIFQQFID 317
           AF++  +N  M+ FL   L++ +F  F++
Sbjct: 304 AFLERFENPEMKLFLNCFLETVMFADFLE 332


>UniRef50_UPI000049911F Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 711

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 60/202 (29%), Positives = 93/202 (46%), Gaps = 21/202 (10%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           ++ ER+   V+     LS  + +    + P  WQH+ IP+LPK LV Y  APMPF+IG  
Sbjct: 184 MMLERKFLFVSDYLMTLSNTISSFITLMSPFVWQHVLIPLLPKSLVTYCAAPMPFVIGCL 243

Query: 202 RSVMENVR--MSEIGDVVILDVD-ANELRSPFNDLETLPPELISSLKKALS-----DKNA 253
           R++   ++    +I DV ++D+D  N +  P   +  L  +    L+  LS     +   
Sbjct: 244 RTLYPEIQNECGDISDVFVIDIDNGNYINKPDFPM-LLVSDTSIGLRNILSNIVSKEPKP 302

Query: 254 LGDAVSRA-FLRALVCLIGGYRDAIK-----IENGQLITFNPEAF--VKTRKNMQP---- 301
             D V RA  L+    L   Y+   K      E+     F P  F   K  K + P    
Sbjct: 303 EDDTVVRAQVLKFFQRLFLNYQKCFKEVKPTEEDKNNPRFKPIQFKWSKFIKKLDPDNEA 362

Query: 302 FLRKILQSQIFQQFIDERLDLL 323
           F+ +  QSQ+   FI+ER ++L
Sbjct: 363 FITEFQQSQMLDMFIEERENML 384


>UniRef50_UPI00015A64BC Cluster: DENN/MADD domain containing 3; n=2;
           Danio rerio|Rep: DENN/MADD domain containing 3 - Danio
           rerio
          Length = 1268

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 58/224 (25%), Positives = 105/224 (46%), Gaps = 30/224 (13%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F    +K +  + A +L E+R+   +S  ++L+   +     ++P+ WQH  +PIL +H+
Sbjct: 260 FLCFKSKEVLQIIACILTEQRMVFFSSDWAKLTLIAECFMLYIWPLRWQHPLVPILSQHM 319

Query: 187 VDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVD------ANELRSPFNDLETLPPEL 240
           +D+++AP  F++G   S  E V   E  D++++++D      ++ L     D+     + 
Sbjct: 320 LDFVMAPTAFIMGCHISHYEEV-AEENDDLILINIDEGTVSCSSILDFDIPDVPYAAAQC 378

Query: 241 ISSLKKALS---DKNALGDAVSRAF--LR-----------------ALVCLIGGYRDAIK 278
             S +K L    D N L  ++      LR                 +L  L   +RD   
Sbjct: 379 FKSRRKGLRLHYDLNLLNQSICGDLNELRNQRRCWQQRLNKEIQNISLELLFNMFRDVSD 438

Query: 279 IENGQLITFNPEAFVKTR-KNMQPFLRKILQSQIFQQFIDERLD 321
             N +   FN + F+KTR    Q F +K+L++ IF  F+ ERL+
Sbjct: 439 YLNYEHRVFNTDEFLKTRDPEDQSFYKKVLETPIFHSFLKERLN 482


>UniRef50_Q9VGH9 Cluster: CG6939-PA, isoform A; n=2; Drosophila
           melanogaster|Rep: CG6939-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 1993

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 64/266 (24%), Positives = 121/266 (45%), Gaps = 37/266 (13%)

Query: 86  PPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHE 145
           PP  G  ++    AG    + Q P S+ LP+     +    F  +  K +  L  +++ E
Sbjct: 192 PPAGGPQVRFSIGAGDKQ-SLQPPQSSSLPTTGSGVHFL--FKQLGIKNVLILLCSVMTE 248

Query: 146 RRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVM 205
            ++  ++     L+   +A  A ++P  + H++IPILP  L + +  P PF++G+  S+ 
Sbjct: 249 NKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQ 308

Query: 206 ENVRMSEIGDVVILDVDANELRSPFNDLETLP----------PELISSL----------- 244
             +  +++ DV+++D+D   +  P +    +P           +L+S +           
Sbjct: 309 TEI--TDLLDVIVVDLDGGLVTIPESLTPPVPILPSPLWEQTQDLLSMILFPNLAQADLA 366

Query: 245 ------KKALSDKNALGDAVSRA-FLRALVCLIGGYRDA---IKIENGQLITFNPEAFVK 294
                   A++  +A  D   RA F+R    L+ GYR     I+I    +ITF+   F+ 
Sbjct: 367 FPTLERPSAIAKTDAQIDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKPVITFHKAGFLG 426

Query: 295 TRKNMQ-PFLRKILQSQIFQQFIDER 319
            R  ++  FL ++L S  F  F++ER
Sbjct: 427 ARDLIESEFLFRVLDSMFFTTFVNER 452


>UniRef50_Q7KSP6 Cluster: CG6939-PB, isoform B; n=5; Diptera|Rep:
           CG6939-PB, isoform B - Drosophila melanogaster (Fruit
           fly)
          Length = 1973

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 64/266 (24%), Positives = 121/266 (45%), Gaps = 37/266 (13%)

Query: 86  PPMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHE 145
           PP  G  ++    AG    + Q P S+ LP+     +    F  +  K +  L  +++ E
Sbjct: 192 PPAGGPQVRFSIGAGDKQ-SLQPPQSSSLPTTGSGVHFL--FKQLGIKNVLILLCSVMTE 248

Query: 146 RRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVM 205
            ++  ++     L+   +A  A ++P  + H++IPILP  L + +  P PF++G+  S+ 
Sbjct: 249 NKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQ 308

Query: 206 ENVRMSEIGDVVILDVDANELRSPFNDLETLP----------PELISSL----------- 244
             +  +++ DV+++D+D   +  P +    +P           +L+S +           
Sbjct: 309 TEI--TDLLDVIVVDLDGGLVTIPESLTPPVPILPSPLWEQTQDLLSMILFPNLAQADLA 366

Query: 245 ------KKALSDKNALGDAVSRA-FLRALVCLIGGYRDA---IKIENGQLITFNPEAFVK 294
                   A++  +A  D   RA F+R    L+ GYR     I+I    +ITF+   F+ 
Sbjct: 367 FPTLERPSAIAKTDAQIDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKPVITFHKAGFLG 426

Query: 295 TRKNMQ-PFLRKILQSQIFQQFIDER 319
            R  ++  FL ++L S  F  F++ER
Sbjct: 427 ARDLIESEFLFRVLDSMFFTTFVNER 452


>UniRef50_Q0IEN0 Cluster: Rab6-interacting; n=2; Culicidae|Rep:
           Rab6-interacting - Aedes aegypti (Yellowfever mosquito)
          Length = 1333

 Score = 67.7 bits (158), Expect = 5e-10
 Identities = 31/111 (27%), Positives = 60/111 (54%), Gaps = 1/111 (0%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F+ +   C+  L+  +L E +V + +S   +L+   +   + LFP  WQH++ PILP  L
Sbjct: 245 FTYLSVDCVIQLFTCVLLENQVLLRSSDYQKLTIIAECITSLLFPFQWQHVYAPILPASL 304

Query: 187 VDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
             ++ AP+PF++G+      ++R+    ++  +DVD   ++ P  +L   P
Sbjct: 305 HHFLDAPVPFVMGLHSDSDNSIRIGSEANLCYVDVDKKSVQLP-EELPAFP 354


>UniRef50_Q9W3D3 Cluster: CG12737-PA, isoform A; n=6;
           Sophophora|Rep: CG12737-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 1671

 Score = 67.3 bits (157), Expect = 6e-10
 Identities = 76/310 (24%), Positives = 133/310 (42%), Gaps = 47/310 (15%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P P   L++   +   +   Q P+ + LP      ++       D  C+  L  AL  E+
Sbjct: 360 PAPSIHLQLSSESNDRILLTQ-PEDSPLPRSGAGFHILLQNLGTDN-CLHVLLLALT-EQ 416

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           ++ I + +P+ L+A  +A  + LFP  WQ  +IP+ P  L + + AP+P+LIGV     +
Sbjct: 417 KILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFD 476

Query: 207 NVRMSEIGDVVILDVDANE----------------------LRSPFNDLETLPP---ELI 241
                   DV  +D+D N                       LR    +LE   P   +  
Sbjct: 477 LYEPPT--DVTCIDLDTNNISLCESQRHLSPKLLPKRAARLLRQTLTELENAKPISYDST 534

Query: 242 SSLKKALSDKN---ALGDAVSRAFLRALVCLIGGYRD-AIKIENGQLI-------TFNPE 290
           +SL + +  +     L   +  AFL  +  ++ GYRD  + I     +        F  +
Sbjct: 535 NSLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLK 594

Query: 291 AFVKTR-KNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSG 349
           AF+++R K+ Q F   ++++Q+F +FI+ER  + +   G +  F  EC   A+K+     
Sbjct: 595 AFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLS--FFDEC---AEKVGNYDE 649

Query: 350 QKLKQQYRDW 359
              +    DW
Sbjct: 650 TPAQLHLVDW 659


>UniRef50_Q8RXA7 Cluster: Stomatal cytokinesis defective; n=3;
           Arabidopsis thaliana|Rep: Stomatal cytokinesis defective
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 1187

 Score = 66.9 bits (156), Expect = 8e-10
 Identities = 66/269 (24%), Positives = 124/269 (46%), Gaps = 46/269 (17%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P PG   +V++   + + + + P  + LP    + +L      +D   +  L+ ++L ER
Sbjct: 174 PTPGKD-RVLFAVENCLLSVEAPPEDSLPQA--DISLQPLVQCLDVDNLIKLFTSVLVER 230

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV-M 205
           R+ I ++K S L+   ++    ++P  W  ++IP+L    VDY+ AP P+++G+   V  
Sbjct: 231 RILIRSNKYSLLTLVSESICHLIYPFRWLQVYIPLLFFSGVDYIDAPTPYMMGLHSDVDT 290

Query: 206 ENVRMSEIGDVVILDVDANELRS-------PFNDLETLPPELISSLKK---ALSDKNALG 255
            N+ M     VV++D+D N++ +       P  +  TL  +++  L     A+      G
Sbjct: 291 SNLAMD---GVVVVDLDINQITTSEEIPQIPEPEFSTLRNDILKLLHPNVVAIDQLKGFG 347

Query: 256 DAVSRA-------------------FLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTR 296
           ++V +                    FL+    ++GGYR+   IEN     F+ +AF+K R
Sbjct: 348 NSVEQCPKSLSKPWGEDHDLQLRVIFLKCFASILGGYRNF--IENK---VFSTDAFLKRR 402

Query: 297 KNM-----QPFLRKILQSQIFQQFIDERL 320
                   +P L + L S  F  +++ RL
Sbjct: 403 SRSTNQPPEPMLVQFLGSFAFLDYLERRL 431


>UniRef50_A7EF60 Cluster: Putative uncharacterized protein; n=3;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Sclerotinia sclerotiorum 1980
          Length = 1089

 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 43/151 (28%), Positives = 77/151 (50%), Gaps = 6/151 (3%)

Query: 112 NKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFP 171
           N+LP    N ++   F A+    +  L   +L E R+ +++S  + L    +A  + L+P
Sbjct: 553 NELPE-SRNTDIYALFRALSIPNIVALVEFMLSESRIILLSSHTAMLHLASKALVSLLYP 611

Query: 172 MSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS--- 228
           + W  IFIP+LP  L+  + AP P+++G+ R   +N+ + E  D V +D+D + + S   
Sbjct: 612 LKWASIFIPVLPARLISALEAPCPYIVGIERR-YDNIVLPE-DDYVFVDLDQDSVESTAP 669

Query: 229 PFNDLETLPPELISSLKKALSDKNALGDAVS 259
           P +       +L+S L+ A    N  G  V+
Sbjct: 670 PVSLPRQQRRKLVSLLQLAAPHHNRCGVEVA 700


>UniRef50_O02626 Cluster: MAP kinase-activating death domain
           protein; n=3; Caenorhabditis|Rep: MAP kinase-activating
           death domain protein - Caenorhabditis elegans
          Length = 1409

 Score = 66.5 bits (155), Expect = 1e-09
 Identities = 55/177 (31%), Positives = 92/177 (51%), Gaps = 14/177 (7%)

Query: 87  PMPGHT---LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           P+PG T   ++V+      VF    PD  +   I    ++      +D   +  L AA+L
Sbjct: 222 PVPGKTKVQIEVMPMDLSQVFEFALPDHTRFTLIDFPLHIPFEILGIDM-ALRVLTAAML 280

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVD---YMLAPMPFLIGV 200
            E ++ I +   + +S C+ +  A L+P+ +    IP+LP ++      +LAP PFLIGV
Sbjct: 281 -EFKIVIQSRNYNAVSMCILSIVALLYPLEYMFPVIPLLPAYMPSAEQLLLAPTPFLIGV 339

Query: 201 PRSVMENVRMSEI-GDVVILDVDANELRSPFNDL--ETLPPELISSLKKALSDKNAL 254
           P S   + ++ E+  DV+++D+D N L+ P +DL    LP    + LK+ L  KNA+
Sbjct: 340 PSSFFHHRKIRELPSDVILVDLDTNCLQVP-DDLYIPDLPEPDATHLKERL--KNAI 393


>UniRef50_Q6ZGD1 Cluster: DENN (AEX-3) domain-containing
           protein-like; n=4; Oryza sativa|Rep: DENN (AEX-3)
           domain-containing protein-like - Oryza sativa subsp.
           japonica (Rice)
          Length = 832

 Score = 66.1 bits (154), Expect = 1e-09
 Identities = 34/108 (31%), Positives = 62/108 (57%), Gaps = 2/108 (1%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+AA L E+++ IV S    LSA V +    + P  WQ + IP+LP  ++D++ AP+P++
Sbjct: 622 LFAAALLEKQIIIVCSNLGMLSASVLSIIPLIRPYQWQSLLIPVLPNDMMDFLDAPVPYI 681

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLK 245
           +GV     +    S + + V++D + N+++S          EL+S+L+
Sbjct: 682 VGVQNKTSD--VHSRLVNAVVIDANKNQIKSTSVPQLPQQKELLSALR 727


>UniRef50_UPI0000DB72B4 Cluster: PREDICTED: similar to CG7852-PA,
           isoform A; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG7852-PA, isoform A - Apis mellifera
          Length = 1282

 Score = 65.7 bits (153), Expect = 2e-09
 Identities = 36/131 (27%), Positives = 72/131 (54%), Gaps = 4/131 (3%)

Query: 111 SNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLF 170
           S +LP +  +  L + F+ +   C+  L+  +L E +V + +S   +L    +   A LF
Sbjct: 271 SQELPML--DYPLKDMFTWLGADCVIQLFTCVLLENQVLLRSSDFHKLMVVSECITALLF 328

Query: 171 PMSWQHIFIPILPKHLVDYMLAPMPFLIGV-PRSVMENVRMSEIGDVVILDVDANELRSP 229
           P SWQH+++PILP  L  ++ AP+PF++G+  +S    ++++   ++  +D+D    + P
Sbjct: 329 PFSWQHVYVPILPASLYHFLDAPVPFIMGLHAQSEGGVLKIASEANLCYVDIDKQSSQFP 388

Query: 230 FNDLETLPPEL 240
             +L   P ++
Sbjct: 389 -EELPVFPHKM 398


>UniRef50_Q10RU8 Cluster: DENN domain containing protein, expressed;
           n=5; Magnoliophyta|Rep: DENN domain containing protein,
           expressed - Oryza sativa subsp. japonica (Rice)
          Length = 941

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 42/131 (32%), Positives = 75/131 (57%), Gaps = 9/131 (6%)

Query: 129 AVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVD 188
           A+  + +  L+AA L E+++ ++ S    LSA V +    + P  WQ + +P+LP+ LVD
Sbjct: 720 ALSLESVLELFAAALLEKQIVVICSNLGVLSAIVLSVMPMIRPFQWQSLLLPVLPRKLVD 779

Query: 189 YMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP--PELISSLK- 245
           ++ AP+PF+ GV      +++M +   +V ++VD +++++    L  LP   EL+S L  
Sbjct: 780 FLDAPVPFIAGVQHK-PPDIKM-KASSIVRINVDKDQVKA--CSLPQLPRFKELVSDLSP 835

Query: 246 --KALSDKNAL 254
               LS +NAL
Sbjct: 836 IHARLSCENAL 846


>UniRef50_Q9VXY2 Cluster: MAP kinase-activating death domain
           protein; n=5; cellular organisms|Rep: MAP
           kinase-activating death domain protein - Drosophila
           melanogaster (Fruit fly)
          Length = 2075

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 46/161 (28%), Positives = 78/161 (48%), Gaps = 13/161 (8%)

Query: 87  PMPGHT---LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           P+PG T   ++V+    H       PD  +   +    +L      V+T C+  +W  ++
Sbjct: 311 PVPGSTRVEVEVLSPTVHEPLLFALPDHTRFSLVDFPLHLPLELLGVET-CLK-VWTLIM 368

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL---VDYMLAPMPFLIGV 200
            E +V   +   + LS  V A    L+P+ +    IP+LP  L      +LAP PF+IGV
Sbjct: 369 QENKVLFQSRDYNALSMSVMAFVTMLYPLEYMFPVIPLLPTCLSCAEQLLLAPTPFVIGV 428

Query: 201 PRSVM---ENVRMSEIGDVVILDVDANELRSPFNDLETLPP 238
           P S +   +N R+ +  D+ ++D+D+ +L  P    E +PP
Sbjct: 429 PASFLVYKKNFRLPD--DIWVVDLDSTKLTPPTGGYEEIPP 467


>UniRef50_UPI0000498ED2 Cluster: protein with DENN and LIM domains;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: protein with
           DENN and LIM domains - Entamoeba histolytica HM-1:IMSS
          Length = 533

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 50/196 (25%), Positives = 90/196 (45%), Gaps = 16/196 (8%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           ++ ER+   +++    LS  +    + ++P  W H+ IPILP  L  Y  APMP+LIG+ 
Sbjct: 194 IMMERKFVFLSNSIGSLSDTILTLTSLIYPFVWHHVLIPILPVQLASYPTAPMPYLIGIK 253

Query: 202 RSVMENVRMSEIG---DVVILDVD-ANELRSP-FNDLETLPPELISSLKKAL------SD 250
            S+ E+V+    G   D +++D++   ++  P F  + T P  ++   + +L       D
Sbjct: 254 TSLWEHVKKECDGGMEDTIVIDLEKGQQIEGPVFPMVFTSPSSILLRSQLSLIQNDPDPD 313

Query: 251 KN--ALGDAVSRAFLRALVCLIGGYRDAIKIENGQLI--TFNPEAFV-KTRKNMQPFLRK 305
           +N     D +   F      +   Y    K   G  I  +F+ +AFV K  ++ + F   
Sbjct: 314 ENIELKNDTIYNMFQLFFFKIFHNYFQCFKANPGGRIKYSFDRDAFVSKLSEDDKLFFES 373

Query: 306 ILQSQIFQQFIDERLD 321
              SQ+   F + R +
Sbjct: 374 FEDSQMCFMFFNTRAE 389


>UniRef50_Q01H37 Cluster: RAS signaling inhibitor ST5; n=4; cellular
           organisms|Rep: RAS signaling inhibitor ST5 -
           Ostreococcus tauri
          Length = 1608

 Score = 64.9 bits (151), Expect = 3e-09
 Identities = 28/106 (26%), Positives = 58/106 (54%), Gaps = 2/106 (1%)

Query: 145 ERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV 204
           ERR+ + +   S +  C +   +   P+ W+H+++P +   +VDY+ APMP+++G+   +
Sbjct: 258 ERRLLLRSQNVSLVVKCAETLRSLAHPLVWRHVYVPCVSTSMVDYVAAPMPYIMGISADI 317

Query: 205 MENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSD 250
           + N R   +  V +LD+D   L    + +   P +++ SL + L +
Sbjct: 318 VVNER--NLDGVAVLDLDQGTLHDGDDRVLMPPADMLHSLTQRLRE 361


>UniRef50_UPI0000499578 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 672

 Score = 64.5 bits (150), Expect = 4e-09
 Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           LL ER+   ++     LS+ V   +  ++P +WQH+ IPILP  L+    APMPF+IG  
Sbjct: 194 LLLERKFIFISESLQLLSSSVHTFSRLIYPFTWQHVLIPILPPDLLSLAFAPMPFIIGCT 253

Query: 202 RSV-MENVRMSEIGDVVILDVDANELRS 228
            S  ++ +   EI DV + ++D +   S
Sbjct: 254 YSTFLQMLEEVEINDVYVFNLDTSTFLS 281


>UniRef50_UPI00006A08E0 Cluster: DENN domain-containing protein 1A.;
           n=1; Xenopus tropicalis|Rep: DENN domain-containing
           protein 1A. - Xenopus tropicalis
          Length = 229

 Score = 64.5 bits (150), Expect = 4e-09
 Identities = 33/56 (58%), Positives = 40/56 (71%), Gaps = 2/56 (3%)

Query: 101 HSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPS 156
           HS FT   PDS +LPSIP+N NLTEYF AVD   M  L+A++L+ERR+ I  SK S
Sbjct: 168 HSYFTV--PDSRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILICCSKLS 221


>UniRef50_A7RH02 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1436

 Score = 64.1 bits (149), Expect = 6e-09
 Identities = 60/226 (26%), Positives = 113/226 (50%), Gaps = 23/226 (10%)

Query: 39  KNEEEIKSIPKFT-FPCSLEKLLNCIANIINSPERDQLHSFLEACRIRP-PMPGHT---L 93
           KN+  I  +  ++ F CS +  L+ IA      + D++ ++++   + P P+ G T   +
Sbjct: 170 KNDNFIPGLHSWSVFTCSEDPKLSPIAT-----QMDEIETWIQRLLLAPAPVIGRTKVDM 224

Query: 94  KVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVAS 153
           +++    +   T   P++ + P I    ++      V+T C+  L   LL E++V I + 
Sbjct: 225 ELLCPESYPSLTFAYPENTRFPLIDFPVHIPMELLGVET-CLKVLTCILL-EQKVVIQSR 282

Query: 154 KPSRLSACVQAANATLFPMSWQHIFIPILPKHLVD---YMLAPMPFLIGVPRSVM--ENV 208
             + L+  V A    L+P+ +    IP+LP  + +    +LAP P++IGVP S    ++ 
Sbjct: 283 DYNALTMSVIALTRLLYPLEYMFPIIPLLPTCMANAEQLLLAPTPYVIGVPASFFRYKSK 342

Query: 209 RMSEIGDVVILDVDANELRSPF--NDLETLPPE----LISSLKKAL 248
                GD+ + D+D+++++ P   ++L  LP E    LI  LK AL
Sbjct: 343 DFQIPGDLWVFDLDSSKVKIPMSADELPDLPEEEGQVLIRRLKMAL 388


>UniRef50_A0C7E2 Cluster: Chromosome undetermined scaffold_155,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_155,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 1066

 Score = 64.1 bits (149), Expect = 6e-09
 Identities = 58/234 (24%), Positives = 111/234 (47%), Gaps = 22/234 (9%)

Query: 37  SYKNEEEIKSIPKFTFPCSLEK----LLNCIANIINSPERDQLHSFLEACRIRPPMPGHT 92
           S+   E+++ + K+ + CSL K    + + I NIIN  +  Q     E   ++  +P + 
Sbjct: 301 SHNYPEQMRELIKYIYRCSLSKNNIPIESTICNIINKIKFPQQIFEQENICLKYVLPSYD 360

Query: 93  LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVA 152
           +              C  +N    +  N  L   F  +D   +  +++A+L E+++  ++
Sbjct: 361 I--------------CFYTNYKYPVGYNEALECLFRLLDINRIINIYSAILLEKKIHFIS 406

Query: 153 SKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV-PRSVMENVRMS 211
           +  S     + A    LFP  +  I IP+LP  L  Y+ AP+PFLIG   ++++E  + +
Sbjct: 407 NHLSVPGLVIDAFLQLLFPFQFTSILIPVLPDSLRGYIEAPVPFLIGYSQKNIIEQNQHT 466

Query: 212 EIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSD-KNALGDAVSRAFLR 264
           ++ D + + +D N + +  N L  +P + +  LK +L    N   D  S+ +LR
Sbjct: 467 QV-DSLYVYLDTNFIVNCEN-LTAIPEKALKKLKSSLKPFNNLFNDDYSKQYLR 518


>UniRef50_UPI0000D556CB Cluster: PREDICTED: similar to CG12737-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG12737-PB, isoform B - Tribolium castaneum
          Length = 1578

 Score = 63.7 bits (148), Expect = 8e-09
 Identities = 41/120 (34%), Positives = 64/120 (53%), Gaps = 8/120 (6%)

Query: 134 CMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAP 193
           C+  L  AL  E+++ I + +P  L+A  +A ++ LFP  WQ  +IP+ P  LV+ + AP
Sbjct: 399 CLQVLLLALT-EQKILIHSLRPDTLTAVAEAVSSFLFPFKWQCPYIPLCPLGLVEVLHAP 457

Query: 194 MPFLIGVPRSVMENVRMSEIGDVVILDVDAN-----ELRSPFNDLETLPPELISSLKKAL 248
           +PFLIGV     +        DV  +D+D N     E +    +++ LP +   SLK AL
Sbjct: 458 LPFLIGVDSRFFD--LYDPPPDVSCIDLDTNIITVAESQRQLLNIKLLPKKPAKSLKSAL 515


>UniRef50_O75064 Cluster: DENN domain-containing protein 4B; n=20;
           Eutheria|Rep: DENN domain-containing protein 4B - Homo
           sapiens (Human)
          Length = 1496

 Score = 63.7 bits (148), Expect = 8e-09
 Identities = 69/261 (26%), Positives = 120/261 (45%), Gaps = 49/261 (18%)

Query: 102 SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSAC 161
           ++  CQ P S+ LP      +  +   ++  +    L  A+L E ++ + + +P  L++ 
Sbjct: 380 NLLLCQ-PVSSPLPL--SGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSV 436

Query: 162 VQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDV 221
            +A  + +FP+ WQ  +IP+ P  L D + AP+PF++G+  S  +        DV+ +D+
Sbjct: 437 CEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFD--LHDPPADVICVDL 494

Query: 222 DANEL---------------RSPFND-LETLP------------PELISSLKKALSDKNA 253
           D N L               R P+   L TL             PE  +SL+  L+D  A
Sbjct: 495 DTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEA 554

Query: 254 -------LGDAVSRAFLRALVCLIGGYRDAIK------IENGQLI--TFNPEAFVKTR-K 297
                  L   V  AFLR + CL+ GYR  ++       E  + +   F  + F+K+R +
Sbjct: 555 VCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRER 614

Query: 298 NMQPFLRKILQSQIFQQFIDE 318
           +      ++L +Q+F QFI+E
Sbjct: 615 SSHKLYSQLLHTQMFSQFIEE 635


>UniRef50_Q54GF5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1275

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 62/244 (25%), Positives = 113/244 (46%), Gaps = 18/244 (7%)

Query: 108 CPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANA 167
           CP  ++   I D  +L   F ++  + +  ++  +L ER V +V+     +SA V +   
Sbjct: 638 CPLGSEDRLIAD-WSLHPTFESLSVEDILNIYCWILLERSVLVVSKNLGNVSALVFSFIP 696

Query: 168 TLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELR 227
            L P  WQ  FIPILP+ L++ + AP P++IG     +    M +  D +I+D+D  +L 
Sbjct: 697 LLKPFVWQCCFIPILPESLIESIDAPFPYIIGYQCEEVGPELMDDKRDYLIVDIDQKKLI 756

Query: 228 SPFNDLETLPPEL---------ISSLKKALSD-KNALG-DAVSRAFLRALVCLIGGYRDA 276
            P + L   PP+L         ++  KK ++D KN +  D +   F +++      Y+  
Sbjct: 757 YPPSTL--TPPKLPGKKKLRDTLTVHKKEMNDLKNQIPIDHLKHRFTQSITTTFREYQTW 814

Query: 277 I--KIENGQLITFNPEAFVKTRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFE 334
           +  +I  G +   N   +++ ++  Q   ++  Q Q  QQ   ++ + LN      D   
Sbjct: 815 LIDQISTGVITCIN-NLYIQKQQQQQQQQQQQQQQQQQQQQQQQQQEELNV-ENIEDSLN 872

Query: 335 VECN 338
            E N
Sbjct: 873 KEIN 876


>UniRef50_Q18780 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 1487

 Score = 63.3 bits (147), Expect = 1e-08
 Identities = 53/207 (25%), Positives = 93/207 (44%), Gaps = 11/207 (5%)

Query: 55  SLEKLLNCIANIINSPERDQL--HSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSN 112
           S   LL  +  II SP    L   S++  C    P+P  ++ +      +    Q P   
Sbjct: 213 STRALLTALHQIIASPSSPHLPLESYIYWCLYEVPLPSPSMTLKIPLLGTTLVVQRPGPK 272

Query: 113 KLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPM 172
           +LP   D+  +   F  +  +    L++  L E ++ + +   SRL    ++  A  FP 
Sbjct: 273 ELPFFDDS--IGSIFDYLPVEKFIRLFSCFLLEHQILLCSKDLSRLMTVCESLLALSFPF 330

Query: 173 SWQHIFIPILPKHLVDYMLAPMPFLIG--VPRSVMENVRMSEIGDVVILDVDANELRSP- 229
            WQ  + P+LP   +D+  AP+P+++G     +V E +  S +  VV LD   +EL    
Sbjct: 331 RWQMTYAPVLPYSKLDFFEAPVPYVMGWYYEDTVPEELFQSNV-CVVDLDTGRSELPEDV 389

Query: 230 --FNDLETLPPELISSLKKALSDKNAL 254
             F     L  ++ +SL++ LSD + +
Sbjct: 390 PVFPGARQLATDIKNSLER-LSDSDKM 415



 Score = 36.3 bits (80), Expect = 1.4
 Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 10/139 (7%)

Query: 191 LAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSD 250
           L P+P L  V R+     R++EI     + VD + ++S F D + L   +          
Sbjct: 478 LQPLP-LENVLRNNSTLARVAEIARRAGVVVDVDNIKSEFADAQNLDSPIARHYFVDAKV 536

Query: 251 KNALGDAVSRAFLRALVC----LIGGY----RDAIKIENGQLITFNPEAFVKTRKNMQ-P 301
            NA+ + V   F+         +IGG     R++ +     +  F+  +F+  + +    
Sbjct: 537 NNAIRECVLNRFVEMFYSYEHFVIGGQGCDDRESYEANRESMADFDKASFLSDQPDSHLT 596

Query: 302 FLRKILQSQIFQQFIDERL 320
           FL   L++Q+F  FID ++
Sbjct: 597 FLAAFLETQMFTSFIDSKI 615


>UniRef50_A7PDY4 Cluster: Chromosome chr11 scaffold_13, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr11 scaffold_13, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 788

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 36/109 (33%), Positives = 63/109 (57%), Gaps = 6/109 (5%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+A  L E+++  V S    LSA V +    + P  WQ   +P+LP  ++D++ AP+P++
Sbjct: 578 LFAGALLEKQIVFVCSNLGILSASVLSIVPLIRPYQWQSWLMPVLPNDMLDFLDAPVPYI 637

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP--PELISSL 244
           +GV     E    S++ +V+++DV  N+++S  + +  LP   EL SSL
Sbjct: 638 VGVKNKTSE--VQSKLTNVILVDVYKNQVKS--STIPQLPKHKELFSSL 682


>UniRef50_Q9Y7Q7 Cluster: Diacylglycerol binding protein; n=1;
           Schizosaccharomyces pombe|Rep: Diacylglycerol binding
           protein - Schizosaccharomyces pombe (Fission yeast)
          Length = 973

 Score = 62.1 bits (144), Expect = 2e-08
 Identities = 53/186 (28%), Positives = 91/186 (48%), Gaps = 8/186 (4%)

Query: 67  INSPERDQLHSFLE-ACRIRPPMPGHTLKVIYNAGH-SVFTCQCPDSNKLPSIPDNCNLT 124
           +NS +   L SF++  C   P  P   L++  N G  +++  + P  N++P   D  +L 
Sbjct: 404 LNSLKSLNLQSFVKNICCDVPLPPKGLLQLQVNVGPLNLYAFRSP-VNEIPGWND-VDLY 461

Query: 125 EYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPK 184
             F A+    +  L+ A L E +V  ++     L    QA    L+P++WQ ++IP+LP+
Sbjct: 462 PLFRALSIPNILVLFEAALMEAKVIFLSENLGMLGYASQALLHLLYPLTWQGLYIPVLPR 521

Query: 185 HLVDYMLAPMPFLIGVPRSV--MENVRMSEIGDVVILDVDANELRSPFNDLETLPPELIS 242
            L+    AP  ++IG       M++V +  I  +V+ D+D N + S F  +  L   L S
Sbjct: 522 RLISCFEAPCSYIIGTLSYFFHMDDVPLDNI-PLVVCDLDKNSV-STFGKIVRLSRSLRS 579

Query: 243 SLKKAL 248
            L+  L
Sbjct: 580 KLQAHL 585


>UniRef50_Q0JLS4 Cluster: Os01g0575500 protein; n=5;
           Magnoliophyta|Rep: Os01g0575500 protein - Oryza sativa
           subsp. japonica (Rice)
          Length = 1248

 Score = 61.7 bits (143), Expect = 3e-08
 Identities = 39/149 (26%), Positives = 74/149 (49%), Gaps = 13/149 (8%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P PG   +V++   + + + + P    LP    + +       +D   +  L+ A+L ER
Sbjct: 175 PTPGKN-RVLFAIENCLLSVEAPPKEWLPHA--DISFQPLVQCLDVDKLIQLFTAVLLER 231

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           R+ + ++K + L+   +A    ++P+ WQH++IPI+    VDY+ AP P+++G+   V  
Sbjct: 232 RILLRSNKYTLLTLVSEAICHLIYPLRWQHVYIPIIFSSGVDYIDAPTPYMMGLHSGV-- 289

Query: 207 NVRMSEIGDVVILDVDANELRSPFNDLET 235
                   D   + +D N   +P+ DL T
Sbjct: 290 --------DTSTVTMDGNACLNPYLDLFT 310


>UniRef50_Q9P3C6 Cluster: Putative uncharacterized protein
           B13I18.170; n=4; Sordariomycetes|Rep: Putative
           uncharacterized protein B13I18.170 - Neurospora crassa
          Length = 1226

 Score = 61.7 bits (143), Expect = 3e-08
 Identities = 32/112 (28%), Positives = 60/112 (53%), Gaps = 3/112 (2%)

Query: 111 SNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLF 170
           +N+LP    N ++   F  +  + +  L+   + E R+  ++S    L     A    L+
Sbjct: 598 ANELPG-SRNIDIYALFRCLSLENIVLLFEYAMSESRIIFLSSHTGMLHLACHALANLLY 656

Query: 171 PMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVD 222
           P+ W  IFIP+LP  L+  + AP P+++G+ R   EN+++ +  D V++D+D
Sbjct: 657 PLKWASIFIPVLPARLISALEAPCPYIVGIERR-YENIQLPD-DDYVLVDLD 706


>UniRef50_UPI00006CD2CF Cluster: hypothetical protein
           TTHERM_00267900; n=1; Tetrahymena thermophila SB210|Rep:
           hypothetical protein TTHERM_00267900 - Tetrahymena
           thermophila SB210
          Length = 1249

 Score = 61.3 bits (142), Expect = 4e-08
 Identities = 26/104 (25%), Positives = 60/104 (57%), Gaps = 1/104 (0%)

Query: 120 NCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFI 179
           N +    F  +  K    L  ++L ER++ +V+S P+ + +  ++    ++P+ W  I+I
Sbjct: 313 NFSFRPLFEKISIKTTISLLQSILLERQIILVSSNPNEIISICESLFTLIYPLKWACIYI 372

Query: 180 PILPKHLVDYMLAPMPFLIGVPRSVMENVR-MSEIGDVVILDVD 222
           P+LP  L + + A MP++IG+ +   + ++  +++ D V++++D
Sbjct: 373 PLLPLQLSEMISAMMPYIIGISKKNFDIIKNKTDLKDKVVVNLD 416


>UniRef50_A1CGV5 Cluster: DDENN domain protein; n=10;
           Pezizomycotina|Rep: DDENN domain protein - Aspergillus
           clavatus
          Length = 1114

 Score = 61.3 bits (142), Expect = 4e-08
 Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 3/117 (2%)

Query: 112 NKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFP 171
           N+LP    N +L   F  +    +  L+   L E R+  ++S  S L    +A    LFP
Sbjct: 508 NELPG-SRNTDLYALFRTLSLSNIMILFEYALTESRIIFLSSHTSMLYLATRALVDLLFP 566

Query: 172 MSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS 228
           + W  + IP+LP  L+  + AP P+++G+ R   E V +    D V++D+DA+ + S
Sbjct: 567 LQWAGVLIPVLPARLIQALEAPCPYIVGIERR-YEKVELPS-DDFVLVDLDADLIES 621


>UniRef50_UPI0000E48609 Cluster: PREDICTED: similar to RAB6
           interacting protein 1; n=6; Deuterostomia|Rep:
           PREDICTED: similar to RAB6 interacting protein 1 -
           Strongylocentrotus purpuratus
          Length = 1628

 Score = 60.9 bits (141), Expect = 6e-08
 Identities = 35/145 (24%), Positives = 70/145 (48%), Gaps = 4/145 (2%)

Query: 56  LEKLLNCIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDSNKLP 115
           LE+L   + +  NSP    + S++       P+P     +++        CQ P   +LP
Sbjct: 171 LEQLFEVVRST-NSPSLP-MESYIFNVLYDVPLPPMGRSMVFTGVSRNIACQRPSRAELP 228

Query: 116 SIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQ 175
                  + + F  + T+ +  L   +  E+++ +V+    RL    +   A LFP +W 
Sbjct: 229 LC--EYAIRDIFDLLGTENVIDLLTCVFLEKQILLVSKDYQRLMLVSECITALLFPFTWP 286

Query: 176 HIFIPILPKHLVDYMLAPMPFLIGV 200
           + ++PILP  ++ ++ AP+PF++G+
Sbjct: 287 YAYVPILPASMLYFLDAPLPFIMGL 311


>UniRef50_UPI0000499224 Cluster: hypothetical protein 12.t00030;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 12.t00030 - Entamoeba histolytica HM-1:IMSS
          Length = 1014

 Score = 60.5 bits (140), Expect = 7e-08
 Identities = 50/230 (21%), Positives = 105/230 (45%), Gaps = 21/230 (9%)

Query: 123 LTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPIL 182
           L+E F       +  +W+ ++   R+       + +   ++     LFP+ W  I I +L
Sbjct: 479 LSELFYHFRISEIIDIWSEIILCERIIFTCKNYNTIVKTIEMFKILLFPLEWVCISITLL 538

Query: 183 PKHLVDYMLAPMPFLIGVPRSVM-ENVRMSEIGDVVILDVDAN--ELRSPFNDLETLPPE 239
           P+ L++ + +P P++IGVP     E   + +  DV+I+D+D    E+     ++  LP  
Sbjct: 539 PRILINQLTSPFPYIIGVPSEYFKEAEEIIKNEDVIIVDIDKGSIEVMKKKKEIIKLPTT 598

Query: 240 L-----------ISSLKKALSDKNALGDAVSRAFLRALVCLIGGYRDAIKI----ENGQL 284
           +           ++ L +    K    + +   F++ +  L+ GY + + I    EN  +
Sbjct: 599 IRTILTSDSEWCLNQLIEKKLTKRIFNEYIQLCFVKGISLLMKGYEEHLGIMKITENDNV 658

Query: 285 ITFNPEAFVKTRK-NMQPFLRKILQSQIFQQFIDERL-DLLNSGRGFNDE 332
             F  E F++ R      FL++++++Q    +I+  L +++N    F D+
Sbjct: 659 YLFEDE-FIRERNIEEHNFLKEMMKTQNVVYYIENTLKNVVNICNEFIDK 707


>UniRef50_UPI0000498334 Cluster: DENN domain protein; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: DENN domain protein -
           Entamoeba histolytica HM-1:IMSS
          Length = 931

 Score = 60.1 bits (139), Expect = 1e-07
 Identities = 36/145 (24%), Positives = 74/145 (51%), Gaps = 6/145 (4%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   P  N LP+ P    L E F   +   +  +   +L   R+   +S  + L   ++ 
Sbjct: 365 TITFPKGNDLPTSP--FILGELFCYFNKTTIIQILNYILLGERIVFTSSDNALLVRTIEN 422

Query: 165 ANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV-MENVRMSEIGDVVILDVDA 223
               +FP+ W  + +PILP+ L++Y+ +P P+++G+P S   E   + +  +++++D+D 
Sbjct: 423 FKLLIFPLQWVCVCVPILPRILLEYLTSPFPYILGLPSSYRAEADPIFKEEELILIDIDN 482

Query: 224 NELRSPFNDLETLPPELISSLKKAL 248
           + + S    ++ + P+L SS+   L
Sbjct: 483 SVIHS---SIKHVTPDLPSSITNTL 504


>UniRef50_Q00T31 Cluster: DENN; n=2; Ostreococcus|Rep: DENN -
           Ostreococcus tauri
          Length = 632

 Score = 59.7 bits (138), Expect = 1e-07
 Identities = 59/210 (28%), Positives = 98/210 (46%), Gaps = 28/210 (13%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L AALL E+++ + ++    LSA   A    L P  WQ +++PILP+H+VD++ AP+PF+
Sbjct: 422 LTAALL-EKQIVVFSNNLGELSAVSLALIPMLRPFKWQSLYLPILPQHMVDFLDAPVPFV 480

Query: 198 IGVPRSVME-NVRMSEI-------GDVVILDVDANELRSP-FNDLETLPPELISSL---- 244
            GV     +   R S +        DV +       LR P  ND+  +   L  ++    
Sbjct: 481 CGVQHKTSDLRARTSHLCRINVYKDDVKLQWEGGKSLRLPRMNDVVRILYPLHQAVVEAS 540

Query: 245 ----KKALSDKNALGDAVSRAFL---RALV-CLIGG--YRDAIKIENG---QLITFNPEA 291
               K+ + D +      S+ FL   RA V  L+    Y     +  G   ++     E+
Sbjct: 541 ANRKKRPVIDPSQAAVEASKEFLGAWRAYVNSLVSSIRYHSITDVNEGGDAKVAILLKES 600

Query: 292 FVKTRKNM-QPFLRKILQSQIFQQFIDERL 320
           F+ T     + F+R  +++Q+F  + DERL
Sbjct: 601 FLGTYTGRDRSFMRAFVETQMFSAYCDERL 630


>UniRef50_A4HMW3 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania braziliensis
          Length = 569

 Score = 59.3 bits (137), Expect = 2e-07
 Identities = 29/83 (34%), Positives = 46/83 (55%)

Query: 140 AALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIG 199
           A L+ E+ + IV    S +S  V +  A + P  W HI IPILP  L+D + AP P+L+G
Sbjct: 216 ADLMLEKHIIIVGPNFSIVSNVVMSLQALVAPFDWMHILIPILPTALLDVLAAPPPYLVG 275

Query: 200 VPRSVMENVRMSEIGDVVILDVD 222
           +  S +  +    +  VV++ +D
Sbjct: 276 ILTSQIPQLTRVPLDSVVVVRLD 298


>UniRef50_UPI00006CFBF6 Cluster: DENN domain; n=1; Tetrahymena
           thermophila SB210|Rep: DENN domain - Tetrahymena
           thermophila SB210
          Length = 1710

 Score = 58.4 bits (135), Expect = 3e-07
 Identities = 43/154 (27%), Positives = 80/154 (51%), Gaps = 8/154 (5%)

Query: 100 GHSVFTCQ-CPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRL 158
           G  +FT + C   NKL  I +N +    F  +  + +  L  ++L E+++ I ++ PS +
Sbjct: 292 GREIFTLRNCV--NKLFEI-ENFSYKPLFMKLSIQNIIDLIQSILLEKQIIIFSNNPSDI 348

Query: 159 SACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMS-EIGDVV 217
               +A    + P++W  ++IP LP  +++ +   +P++IG+ R+  + V  S E  + V
Sbjct: 349 IHLCEALFTFIRPLTWNCLYIPFLPTQMIETLHIMVPYIIGIHRNNKDQVLSSVESENKV 408

Query: 218 ILDVDANELRSPFNDLETLPPELISSLKKALSDK 251
            LD+D++ +     D   LP  L   LK+ L DK
Sbjct: 409 FLDLDSDYI---IQDGLQLPEFLKFHLKEQLRDK 439


>UniRef50_Q7PRP6 Cluster: ENSANGP00000001501; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000001501 - Anopheles gambiae
           str. PEST
          Length = 1663

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 45/160 (28%), Positives = 79/160 (49%), Gaps = 13/160 (8%)

Query: 87  PMPGHT---LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           P+PG T   + V+  A +       PD  +   +    +L      VDT C+  L   LL
Sbjct: 266 PVPGSTRVEVDVLSAALYQPLVFALPDHTRFTLVDFPLHLPLELLGVDT-CLRVLTLILL 324

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL---VDYMLAPMPFLIGV 200
            E +V I +   + LS  V A    ++P+ +    IP+LP  +      +LAP P++IG+
Sbjct: 325 -EHKVIIQSRNYNALSMSVMAFVHLIYPLEYMFPVIPLLPTCMGSAEQLLLAPTPYIIGL 383

Query: 201 PRSVM---ENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
           P + +   +N R+ +  D+ ++D+D+N+L     D+E +P
Sbjct: 384 PATFLMYKKNFRLPD--DIWLVDLDSNKLTPASGDMEAIP 421


>UniRef50_Q4DVP9 Cluster: Putative uncharacterized protein; n=2;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 538

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 28/89 (31%), Positives = 48/89 (53%)

Query: 131 DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
           +T+ +  + A LL E+RV +V      +S  V +  + + P  W HI  PILP  L+D +
Sbjct: 210 ETETLFSVLADLLLEKRVIVVGPNFGLVSHVVMSLQSLISPFDWMHILAPILPSSLMDVL 269

Query: 191 LAPMPFLIGVPRSVMENVRMSEIGDVVIL 219
            AP P+L+G+  S +  +    I + V++
Sbjct: 270 AAPTPYLVGILNSQIPLLERVPIENCVLI 298


>UniRef50_Q22KG2 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1110

 Score = 58.0 bits (134), Expect = 4e-07
 Identities = 29/105 (27%), Positives = 57/105 (54%), Gaps = 2/105 (1%)

Query: 145 ERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV 204
           E+++ I++   S ++   +A  + +FP  W H++IPILP     YM AP+P +IG+ + +
Sbjct: 375 EKKLFIISKYKSVITQVAEALISLIFPFQWNHVYIPILPDMFKTYMEAPLPLIIGLEQKL 434

Query: 205 ME-NVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKAL 248
              ++      + +   +D+N+L +    +  LP + +  LKK L
Sbjct: 435 KNFDISSGIQSESIQAYLDSNDLIN-IEWMPALPEKFLKQLKKRL 478


>UniRef50_UPI0000F201E9 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Danio rerio|Rep: PREDICTED: hypothetical
           protein, partial - Danio rerio
          Length = 1011

 Score = 57.6 bits (133), Expect = 5e-07
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 5/125 (4%)

Query: 102 SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSAC 161
           ++  CQ P S+ LP      +  +    +  +    L  A+L E ++ + + +P  L++ 
Sbjct: 253 NLLLCQ-PVSSPLPL--SGASFVKLLQNLGPENTCSLLLAVLTEHKLLLHSLRPDVLTSV 309

Query: 162 VQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDV 221
            +A  +  FP+ W   +IP+ P  + D + APMPF++GV  S  +        DVV +D+
Sbjct: 310 SEALLSMTFPLRWHCPYIPLCPLRMADVLCAPMPFIVGVHSSYFD--LYDPPSDVVCVDL 367

Query: 222 DANEL 226
           D N +
Sbjct: 368 DTNTI 372



 Score = 36.3 bits (80), Expect = 1.4
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 258 VSRAFLRALVCLIGGYRD---AIKIENGQLIT-----FNPEAFVKTR-KNMQPFLRKILQ 308
           +  AFLR + CL+ GYR     I        T     FN + F+K+R +  Q F  ++ +
Sbjct: 439 IQEAFLRFMSCLLRGYRSYLLPITQAPSDRTTDCSSLFNLQGFLKSRDRTQQKFYTQLTK 498

Query: 309 SQIFQQFIDE 318
           +Q+F QFI+E
Sbjct: 499 TQMFTQFIEE 508


>UniRef50_A0PJS2 Cluster: LOC798528 protein; n=5; Euteleostomi|Rep:
           LOC798528 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 704

 Score = 57.6 bits (133), Expect = 5e-07
 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 5/125 (4%)

Query: 102 SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSAC 161
           ++  CQ P S+ LP      +  +    +  +    L  A+L E ++ + + +P  L++ 
Sbjct: 372 NLLLCQ-PVSSPLPL--SGASFVKLLQNLGPENTCSLLLAVLTEHKLLLHSLRPDVLTSV 428

Query: 162 VQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDV 221
            +A  +  FP+ W   +IP+ P  + D + APMPF++GV  S  +        DVV +D+
Sbjct: 429 SEALLSMTFPLRWHCPYIPLCPLRMADVLCAPMPFIVGVHSSYFD--LYDPPSDVVCVDL 486

Query: 222 DANEL 226
           D N +
Sbjct: 487 DTNTI 491



 Score = 36.3 bits (80), Expect = 1.4
 Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 9/70 (12%)

Query: 258 VSRAFLRALVCLIGGYRD---AIKIENGQLIT-----FNPEAFVKTR-KNMQPFLRKILQ 308
           +  AFLR + CL+ GYR     I        T     FN + F+K+R +  Q F  ++ +
Sbjct: 558 IQEAFLRFMSCLLRGYRSYLLPITQAPSDRTTDCSSLFNLQGFLKSRDRTQQKFYTQLTK 617

Query: 309 SQIFQQFIDE 318
           +Q+F QFI+E
Sbjct: 618 TQMFTQFIEE 627


>UniRef50_UPI0000ECC1A9 Cluster: DENN domain-containing protein 4C.;
           n=2; Gallus gallus|Rep: DENN domain-containing protein
           4C. - Gallus gallus
          Length = 1404

 Score = 57.2 bits (132), Expect = 7e-07
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 4/138 (2%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P P     ++  + H       P S  LP      N +     +  +  A L   +L E 
Sbjct: 257 PSPQRPRILVQLSAHDALILSQPVSTPLPL--SGANFSTLLMNLGPENCATLLLFVLLEG 314

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           ++ + + +P+ L+   +A  A +FP  WQ  +IP+ P  L   + AP+PF++GV     +
Sbjct: 315 KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLATVLSAPVPFIVGVDSRYFD 374

Query: 207 NVRMSEIGDVVILDVDAN 224
                +  D+V +D+D N
Sbjct: 375 LYDPPQ--DIVCIDLDTN 390


>UniRef50_A0D0B3 Cluster: Chromosome undetermined scaffold_33, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_33,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 634

 Score = 57.2 bits (132), Expect = 7e-07
 Identities = 49/231 (21%), Positives = 113/231 (48%), Gaps = 16/231 (6%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           FS +  K +  +  +++ E+++ +  ++   L+  V+A    ++P+ W+ I+IP LP  +
Sbjct: 206 FSKLSIKSIIKVVQSIILEKQIILFTTQVWDLANIVEAFLQFIYPLQWRCIYIPYLPAEI 265

Query: 187 VDYMLAPMPFLIGVPRSVMENV-RMSEIGDVVILDVDANELRSPFNDLETLPPELISSLK 245
           +D +   +P++IGV  ++ E V    +  D +++D+D + +    N +   P +L+ +L 
Sbjct: 266 LDTLYVSVPYIIGVHCNLKERVLTQYDCLDKILVDLDQDRVIG-CNLILPFPEQLVETLT 324

Query: 246 KALSDKNALGDA----VSRAFLRALVCLIGG------YRDAIKIENGQLITFNPEAFVKT 295
              S      D+    V   FL+  + LI        Y D ++++      F+ + +++ 
Sbjct: 325 NQSSKFQYSDDSELLQVQCCFLKFQLQLINNIVPYFIYSDTLQLKPKIEDIFDKDLYIEQ 384

Query: 296 RKNM-QPFLRKIL-QSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKL 344
              + Q F R+ + ++ +F +FI+E    L+  +    +  ++ N + D L
Sbjct: 385 FTPLDQEFYREFVNKTMMFPRFIEESYQYLHQKQFL--KLNIKTNIFIDLL 433


>UniRef50_Q5VZ89 Cluster: DENN domain-containing protein 4C; n=23;
           Euteleostomi|Rep: DENN domain-containing protein 4C -
           Homo sapiens (Human)
          Length = 1673

 Score = 56.8 bits (131), Expect = 9e-07
 Identities = 37/140 (26%), Positives = 63/140 (45%), Gaps = 4/140 (2%)

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHER 146
           P P     ++  + H       P S  LP      N +     +  +  A L   +L E 
Sbjct: 123 PSPQRPRILVQLSVHDALILSQPVSTPLPL--SGANFSTLLMNLGPENCATLLLFVLLES 180

Query: 147 RVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVME 206
           ++ + + +P+ L+   +A  A +FP  WQ  +IP+ P  L   + AP+PF++GV     +
Sbjct: 181 KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFD 240

Query: 207 NVRMSEIGDVVILDVDANEL 226
                +  DVV +D+D N L
Sbjct: 241 LHDPPQ--DVVCIDLDTNML 258


>UniRef50_UPI0000E254A2 Cluster: PREDICTED: similar to DENN/MADD
           domain containing 1C, partial; n=1; Pan troglodytes|Rep:
           PREDICTED: similar to DENN/MADD domain containing 1C,
           partial - Pan troglodytes
          Length = 130

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 29/48 (60%), Positives = 35/48 (72%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPS 156
           PDS +LPSIP+N NLTE   AV  + + GL+AALL ERRV + ASK S
Sbjct: 47  PDSGRLPSIPENRNLTELVVAVTDENIVGLFAALLAERRVLLTASKLS 94


>UniRef50_UPI0000DB7B17 Cluster: PREDICTED: similar to
           Calmodulin-binding protein related to a Rab3 GDP/GTP
           exchange protein CG12737-PA, isoform A; n=1; Apis
           mellifera|Rep: PREDICTED: similar to Calmodulin-binding
           protein related to a Rab3 GDP/GTP exchange protein
           CG12737-PA, isoform A - Apis mellifera
          Length = 1512

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 64/229 (27%), Positives = 108/229 (47%), Gaps = 38/229 (16%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV- 200
           +L E+++ + + +P  L++  +A    LFP  WQ  +IP+ P  L + + AP+PFLIGV 
Sbjct: 416 ILTEQKILVHSLRPDVLTSVSEAIAMILFPFKWQCPYIPLCPLGLAEVLHAPLPFLIGVD 475

Query: 201 ---------PRSV----MENVRMSEIGDVVILDVD------ANELRSPFNDL---ETLPP 238
                    P  V    ++   ++   D   L+V       A +LR+    L   + +  
Sbjct: 476 SRFFDLYDPPSDVNCVNLDTNNIAICDDKKYLNVKLLPKKAARQLRNWLEHLYSSKLISW 535

Query: 239 ELISSLKKALSDK---NALGDAVSRAFLRALVCLIGGYRD-AIKIENGQLI-------TF 287
             +SS+K  +S K    AL   +  AFLR    ++ GYR   + I     +        F
Sbjct: 536 VKVSSMKGIISTKRKEQALELEIQDAFLRFTATILKGYRAFLLPITKAPTVGSTDPTSLF 595

Query: 288 NPEAFVKTR-KNMQPFLRKILQSQIFQQFIDER---LDLLNSGRGFNDE 332
           N  AF+++R K    F   ++++Q+F +FI+ER    D+  +G  F DE
Sbjct: 596 NILAFLRSRDKAHAKFYSMLVKTQMFIRFIEERSFVSDMDMAGLAFFDE 644


>UniRef50_Q4SZS2 Cluster: Chromosome undetermined SCAF11526, whole
           genome shotgun sequence; n=2; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF11526,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1555

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 29/87 (33%), Positives = 49/87 (56%), Gaps = 2/87 (2%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L  A+L E ++ + + +P  L++  +A  +  FP+ W   +IP+ P  + D +LAPMPF+
Sbjct: 439 LLLAVLTEHKLLLHSLRPDVLTSVSEALVSMSFPLRWICPYIPLCPLQMADVLLAPMPFI 498

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDAN 224
           +GV  S  +        DVV +D+D N
Sbjct: 499 VGVHSSYFD--LYDPPADVVCVDLDTN 523



 Score = 37.9 bits (84), Expect = 0.44
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 9/88 (10%)

Query: 240 LISSLKKALSDKNALGDAVSRAFLRALVCLIGGYRD-AIKIENGQLIT-------FNPEA 291
           L++   +   ++  L   +  AFLR + CL+ GYR   + I      T       FN + 
Sbjct: 590 LLTDYDQIYRNQKQLELEIQEAFLRFMSCLLRGYRSFLLPITQAPSDTTTDCTSLFNLQG 649

Query: 292 FVKTR-KNMQPFLRKILQSQIFQQFIDE 318
           F+K+R +  Q F  ++ ++Q+F QFI+E
Sbjct: 650 FLKSRERTQQKFYGQLTRTQMFTQFIEE 677


>UniRef50_A2EIL7 Cluster: Putative uncharacterized protein; n=2;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 423

 Score = 56.4 bits (130), Expect = 1e-06
 Identities = 29/103 (28%), Positives = 58/103 (56%), Gaps = 2/103 (1%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           +L +    IV+S  + LS    A    + P+ W HIF PILP  +++ + +P PF++G+ 
Sbjct: 180 MLTDAPFMIVSSDLNELSQFCFALYCLVHPLKWFHIFAPILPLSILETVQSPAPFIVGIH 239

Query: 202 RSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSL 244
            S++  +  S+I   V +D+D+  ++    +L ++P  + +S+
Sbjct: 240 SSLLSKITNSDIEAHVYIDIDSLTIKRV--NLPSIPQWVTNSI 280


>UniRef50_UPI0000499D60 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 642

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 50/213 (23%), Positives = 92/213 (43%), Gaps = 13/213 (6%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILP--KHLVDYMLAPMPFLIG 199
           LL E  + +V S    +   +QA    L P  WQ + IP+LP  +    +   P P L G
Sbjct: 193 LLEENTMFLVESIDQGMPI-IQAFLQILIPFEWQGVLIPMLPIEESYAGFAGCPTPMLFG 251

Query: 200 VPRSVMENVRM--SEIGDVVILDVDANELRSPFNDLETLP----PELISSLKKALSDKNA 253
             +  + N+    S   D+ I +V  ++ +   + L          L++ LK  + +   
Sbjct: 252 TTQQGLININKLYSNTLDINIYNVSTSKFQKRKSGLNLFAFKETGRLLNQLKSIIDNPTF 311

Query: 254 L--GDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKN-MQPFLRKILQSQ 310
                 +   F +  + L G Y    + ++   + FN + F+K+  N +Q FL    QSQ
Sbjct: 312 EHPDSLICNCFSQLFLDLFGRYFAFFEQQSIGFV-FNDKNFIKSSSNELQVFLTAFNQSQ 370

Query: 311 IFQQFIDERLDLLNSGRGFNDEFEVECNAYADK 343
           +F++FI  R++ ++    F     ++C  +  K
Sbjct: 371 MFERFIQHRINYISVMPEFRRSIFIDCPLFKSK 403


>UniRef50_Q9W0E1 Cluster: CG7852-PA, isoform A; n=3; Sophophora|Rep:
           CG7852-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 1449

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 28/111 (25%), Positives = 54/111 (48%), Gaps = 1/111 (0%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F  +  +C+  L   +L E +V + ++   RL    +   + LFP  W H++ PILP  L
Sbjct: 338 FKYLGVECVIQLLTCVLLENQVLLRSTDYQRLMIVGECITSLLFPFVWPHVYAPILPAAL 397

Query: 187 VDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
             ++ AP+PF++G+        ++     +  +D+D   ++ P  +L   P
Sbjct: 398 HHFLDAPVPFVMGLHAECEAAHKIGSEATLCFVDIDKKHIQLP-EELPVFP 447


>UniRef50_A2RUS2 Cluster: DENN domain-containing protein 3; n=22;
           Eukaryota|Rep: DENN domain-containing protein 3 - Homo
           sapiens (Human)
          Length = 1198

 Score = 56.0 bits (129), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 47/81 (58%), Gaps = 1/81 (1%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           +L E+R+   +S  + L+   +   A L+P+ WQH F+PIL   ++D+++AP  FL+G  
Sbjct: 210 ILTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCH 269

Query: 202 RSVMENVRMSEIGDVVILDVD 222
               E V   E   +V++++D
Sbjct: 270 LDHFEEV-SKEADGLVLINID 289


>UniRef50_UPI0000498BD5 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 180

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 3/131 (2%)

Query: 98  NAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSR 157
           N     F  Q  +S++L     N +++          +  L   LL ER+   V+     
Sbjct: 28  NISFHYFPYQVINSDELND-HSNYDVSILLKTFGASALVDLIGYLLVERKFLFVSQSIQS 86

Query: 158 LSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENV--RMSEIGD 215
           LS  +    + +     QH++IP+LP  L+ Y  APM ++IGV  + + NV     ++ D
Sbjct: 87  LSTFIIVFTSLISSFQLQHVYIPVLPLSLLKYCAAPMLYIIGVKNNFLPNVYKDCGKMDD 146

Query: 216 VVILDVDANEL 226
            ++L+VD  +L
Sbjct: 147 TIVLEVDNGKL 157


>UniRef50_UPI000065FFA3 Cluster: DENN/MADD domain containing 4B.;
           n=1; Takifugu rubripes|Rep: DENN/MADD domain containing
           4B. - Takifugu rubripes
          Length = 1215

 Score = 55.6 bits (128), Expect = 2e-06
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 2/89 (2%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L  A+L E ++ + + +P  L++  +A  +  FP+ W   +IP+ P  + D +LAPMPF+
Sbjct: 136 LLLAVLTEHKLLLHSLRPDVLTSVSEALVSMSFPLRWICPYIPLCPLQMADVLLAPMPFI 195

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANEL 226
           +GV  S  +        DVV +D+D N +
Sbjct: 196 VGVHSSYFD--LHDPPTDVVCVDLDTNTI 222



 Score = 37.1 bits (82), Expect = 0.78
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 9/70 (12%)

Query: 258 VSRAFLRALVCLIGGYRD-AIKIENGQLIT-------FNPEAFVKTR-KNMQPFLRKILQ 308
           +  AFLR + CL+ GYR   + I      T       FN + F+K+R +  Q F  ++ +
Sbjct: 289 IQEAFLRFMSCLLRGYRSFLLPITQAPSDTTTDCSSLFNLQGFLKSRERTQQKFYIQLTR 348

Query: 309 SQIFQQFIDE 318
           +Q+F QFI+E
Sbjct: 349 TQMFTQFIEE 358


>UniRef50_UPI000065F171 Cluster: DENN domain-containing protein 4C.;
           n=1; Takifugu rubripes|Rep: DENN domain-containing
           protein 4C. - Takifugu rubripes
          Length = 1563

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 35/118 (29%), Positives = 59/118 (50%), Gaps = 10/118 (8%)

Query: 140 AALLH----ERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMP 195
           A LLH    E ++ + + +P+ L+   +A  A +FP  WQ  ++P+ P  L   + AP+P
Sbjct: 362 ATLLHFVLLENKILLHSLRPAVLTGVAEAVAAMIFPFQWQCPYVPLCPLSLAGVLNAPLP 421

Query: 196 FLIGVPRSVMENVRMSEIGDVVILDVDANEL----RSPFNDLETLPPELISSLKKALS 249
           F++GV     +        DVV +D+D N +        N+ + LP +   SL  +LS
Sbjct: 422 FIVGVDSRYFD--LYDPPPDVVCVDLDTNTVYLSDEKRHNNWKNLPKKPCKSLIGSLS 477


>UniRef50_O08873 Cluster: MAP kinase-activating death domain
           protein; n=35; Amniota|Rep: MAP kinase-activating death
           domain protein - Rattus norvegicus (Rat)
          Length = 1602

 Score = 55.2 bits (127), Expect = 3e-06
 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 10/163 (6%)

Query: 93  LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVA 152
           ++V+        T   PD ++   +    +L      VD  C+  L   LL E +V + +
Sbjct: 268 IEVLPQEVQQALTFALPDPSRFTLVDFPLHLPLELLGVDA-CLQVLTCILL-EHKVVLQS 325

Query: 153 SKPSRLSACVQAANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENV 208
              + LS  V A  A ++P+ +    IP+LP  +      +LAP P++IGVP S  +  +
Sbjct: 326 RDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKL 385

Query: 209 RMSEIGDVVILDVDANELRSPFNDLETLP--PELIS-SLKKAL 248
                 DV ++D+D+N + +P N  E LP  PE  S  LKK L
Sbjct: 386 DFKMPDDVWLVDLDSNRVIAPTN-AEVLPILPEPESLELKKHL 427


>UniRef50_A2AGQ3 Cluster: MAP-kinase activating death domain; n=22;
           Deuterostomia|Rep: MAP-kinase activating death domain -
           Mus musculus (Mouse)
          Length = 1541

 Score = 54.8 bits (126), Expect = 4e-06
 Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 10/163 (6%)

Query: 93  LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVA 152
           ++V+        T   PD ++   +    +L      VD  C+  L   LL E +V + +
Sbjct: 268 IEVLPQELQQALTFALPDPSRFTLVDFPLHLPLELLGVDA-CLQVLTCILL-EHKVVLQS 325

Query: 153 SKPSRLSACVQAANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENV 208
              + LS  V A  A ++P+ +    IP+LP  +      +LAP P++IGVP S  +  +
Sbjct: 326 RDYNALSMSVMAFVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKL 385

Query: 209 RMSEIGDVVILDVDANELRSPFNDLETLP--PELIS-SLKKAL 248
                 DV ++D+D+N + +P N  E LP  PE  S  LKK L
Sbjct: 386 DFKMPDDVWLVDLDSNRVIAPTN-AEVLPILPEPESLELKKHL 427


>UniRef50_UPI00006CBA46 Cluster: hypothetical protein TTHERM_00499360;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00499360 - Tetrahymena thermophila SB210
          Length = 1272

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 27/70 (38%), Positives = 38/70 (54%)

Query: 131  DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
            D K    L+ +LL ER V  V+   S LS  +   ++ L P+ W H  I  LPK L DY+
Sbjct: 1043 DIKYFVKLYISLLLERSVVFVSMSRSVLSQFILLFHSILKPLKWTHAMITTLPKSLFDYL 1102

Query: 191  LAPMPFLIGV 200
             +P P +IG+
Sbjct: 1103 HSPTPIIIGI 1112


>UniRef50_Q4SJ20 Cluster: Chromosome 21 SCAF14577, whole genome
           shotgun sequence; n=5; Tetraodontidae|Rep: Chromosome 21
           SCAF14577, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 2176

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 26/98 (26%), Positives = 58/98 (59%), Gaps = 1/98 (1%)

Query: 140 AALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIG 199
           + LL E+++  ++S  +RL+   ++    L P+SWQ  ++P+L   ++D+++AP  FL+G
Sbjct: 169 SCLLQEQKLVFLSSDWARLTLVAESLLLYLQPLSWQQPYVPVLAGGMLDFLMAPTAFLMG 228

Query: 200 VPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
              S  E +  +E  +++++++D   ++S   +   LP
Sbjct: 229 CHISHFEEI-AAETEELLLVNIDDGIIQSSCAETVDLP 265


>UniRef50_A7RR72 Cluster: Predicted protein; n=7; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 875

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 2/85 (2%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+  +L E ++ I + +P+ L++  +A    LFP +WQ  +IP+ P  L D + AP PF+
Sbjct: 397 LFYLILTEHKILIHSLRPALLTSVAEALTNVLFPFTWQCPYIPLCPVALNDVLCAPCPFI 456

Query: 198 IGVPRSVMENVRMSEIGDVVILDVD 222
           IG+     +     +  DV  +D+D
Sbjct: 457 IGIDSRYFDQYDPPD--DVTSVDLD 479


>UniRef50_Q8WXG6 Cluster: MAP kinase-activating death domain
           protein; n=34; Euteleostomi|Rep: MAP kinase-activating
           death domain protein - Homo sapiens (Human)
          Length = 1647

 Score = 54.4 bits (125), Expect = 5e-06
 Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 10/151 (6%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   PD ++   +    +L      VD  C+  L   LL E +V + +   + LS  V A
Sbjct: 281 TFALPDPSRFTLVDFPLHLPLELLGVDA-CLQVLTCILL-EHKVVLQSRDYNALSMSVMA 338

Query: 165 ANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENVRMSEIGDVVILD 220
             A ++P+ +    IP+LP  +      +LAP P++IGVP S  +  +      DV ++D
Sbjct: 339 FVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKLDFKMPDDVWLVD 398

Query: 221 VDANELRSPFNDLETLP--PELIS-SLKKAL 248
           +D+N + +P N  E LP  PE  S  LKK L
Sbjct: 399 LDSNRVIAPTN-AEVLPILPEPESLELKKHL 428


>UniRef50_UPI00015A7BBA Cluster: MAP kinase-activating death domain
           protein (Differentially expressed in normal and
           neoplastic cells) (Insulinoma-glucagonoma clone 20)
           (Rab3 GDP/GTP exchange factor).; n=3; Danio rerio|Rep:
           MAP kinase-activating death domain protein
           (Differentially expressed in normal and neoplastic
           cells) (Insulinoma-glucagonoma clone 20) (Rab3 GDP/GTP
           exchange factor). - Danio rerio
          Length = 1544

 Score = 54.0 bits (124), Expect = 6e-06
 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 8/150 (5%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   PD ++   +    +L      VD  C+  L A +L E +V + +   + LS  V A
Sbjct: 289 TFALPDPSRFSIVDFPLHLPLELLGVDA-CLQVL-ACILLEHKVVLQSRDYNALSMSVMA 346

Query: 165 ANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENVRMSEIGDVVILD 220
             + ++P+ +    IP+LP  +      +LAP P++IGVP S  +         DV ++D
Sbjct: 347 FVSMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYVIGVPASFFLYKCDFKMPDDVWLVD 406

Query: 221 VDANELRSPFND--LETLPPELISSLKKAL 248
           +D N++  P N   L  LP    S LKK L
Sbjct: 407 LDCNKVIVPSNAELLPPLPEPEASELKKHL 436


>UniRef50_UPI00015A7BA8 Cluster: MAP kinase-activating death domain
           protein (Differentially expressed in normal and
           neoplastic cells) (Insulinoma-glucagonoma clone 20)
           (Rab3 GDP/GTP exchange factor).; n=2; Danio rerio|Rep:
           MAP kinase-activating death domain protein
           (Differentially expressed in normal and neoplastic
           cells) (Insulinoma-glucagonoma clone 20) (Rab3 GDP/GTP
           exchange factor). - Danio rerio
          Length = 1664

 Score = 54.0 bits (124), Expect = 6e-06
 Identities = 45/150 (30%), Positives = 71/150 (47%), Gaps = 8/150 (5%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   PD ++   +    +L      VD  C+  L A +L E +V + +   + LS  V A
Sbjct: 290 TFALPDPSRFSIVDFPLHLPLELLGVDA-CLQVL-ACILLEHKVVLQSRDYNALSMSVMA 347

Query: 165 ANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENVRMSEIGDVVILD 220
             + ++P+ +    IP+LP  +      +LAP P++IGVP S  +         DV ++D
Sbjct: 348 FVSMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYVIGVPASFFLYKCDFKMPDDVWLVD 407

Query: 221 VDANELRSPFND--LETLPPELISSLKKAL 248
           +D N++  P N   L  LP    S LKK L
Sbjct: 408 LDCNKVIVPSNAELLPPLPEPEASELKKHL 437


>UniRef50_Q4RI35 Cluster: Chromosome 8 SCAF15044, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
           SCAF15044, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1308

 Score = 54.0 bits (124), Expect = 6e-06
 Identities = 24/98 (24%), Positives = 56/98 (57%), Gaps = 1/98 (1%)

Query: 140 AALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIG 199
           + LL E+R+ + ++  +RL+   ++    L P+SWQ  ++P+L + ++D+++ P   L+G
Sbjct: 243 SCLLQEQRIVLFSADFARLTLVAESFLLFLQPLSWQQPYVPVLSRSMLDFLMVPTALLMG 302

Query: 200 VPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP 237
                 E V  +E  D++++++D   + +  ++   LP
Sbjct: 303 CHVCHFEEV-AAETDDLILVNIDDGSVSTSSSETVDLP 339


>UniRef50_Q4SHF6 Cluster: Chromosome 5 SCAF14581, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 5 SCAF14581, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1795

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 46/156 (29%), Positives = 77/156 (49%), Gaps = 14/156 (8%)

Query: 105 TCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQA 164
           T   P++++   +    +L      VD  C+  L   LL E +V + +   + LS  V A
Sbjct: 296 TFALPENSRFCLVDFPLHLPLELLGVDA-CLQVLSCVLL-EHKVILQSRDYNALSMSVMA 353

Query: 165 ANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGVPRS-VMENVRMSEIGDVVILD 220
             A ++P+ +    IP+LP  +      +LAP P++IGVP S  +         DV ++D
Sbjct: 354 FVAMIYPLEYMFPVIPLLPTCMASAEQLLLAPTPYIIGVPASFFLYKAEFKIPDDVWLVD 413

Query: 221 VDANELRSPFNDLETLPP-------ELISSLKKALS 249
           +D++++ +P N  E LPP       EL   LK+AL+
Sbjct: 414 LDSSKVIAPTN-AEILPPLPEPEAMELKKHLKQALA 448


>UniRef50_Q9TXV4 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 1635

 Score = 52.8 bits (121), Expect = 1e-05
 Identities = 42/162 (25%), Positives = 71/162 (43%), Gaps = 9/162 (5%)

Query: 94  KVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVAS 153
           +V    G    +    D ++LP   +   L +    + ++ +  L    L E+++ I + 
Sbjct: 406 RVFMQLGAENISFDSHDDSQLPL--NGAQLIDTLKYLGSENLMYLMLLALLEQKILIHSL 463

Query: 154 KPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEI 213
           +P  L+A  ++  A +FP  WQ  +IP  P  L   + AP+PF+ GV     E +     
Sbjct: 464 RPWMLAAVAESVCALMFPFHWQCPYIPQCPLGLAGVLHAPLPFIAGVDSRYFE-LYEDPP 522

Query: 214 GDVVILDVDANEL-----RSPFNDLETLPPELISSLKKALSD 250
            DV   D+D + +     R+ F     LP +    LK AL D
Sbjct: 523 DDVTCFDLDTSTISFSTVRATFK-TSMLPKKPAKQLKSALED 563


>UniRef50_UPI0000F20348 Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 506

 Score = 52.0 bits (119), Expect = 3e-05
 Identities = 23/82 (28%), Positives = 47/82 (57%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F    +K +  + A ++ E+R+   +S  ++L+   +     ++P+ WQH  +PIL +H+
Sbjct: 264 FLCFKSKEVLQIIACIMTEQRMVFFSSDWAKLTLIAECFMLYIWPLRWQHPLVPILSQHM 323

Query: 187 VDYMLAPMPFLIGVPRSVMENV 208
           +D+++AP  F++G   S  E V
Sbjct: 324 LDFVMAPTAFIMGCHISHYEEV 345


>UniRef50_Q7QWY3 Cluster: GLP_511_47995_52011; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_511_47995_52011 - Giardia lamblia
           ATCC 50803
          Length = 1338

 Score = 51.2 bits (117), Expect = 4e-05
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 4/125 (3%)

Query: 111 SNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLF 170
           +N  PS+  + N    FS V    +     ALL  R V  +     R+S CV      L+
Sbjct: 259 NNCFPSV--SVNFLTLFSHVSPNAIVDTLEALLQSRTVLFIGKSLHRVSMCVIEMWTLLY 316

Query: 171 PMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPF 230
           P S+   F+P++    +  + +P P L G  RSV+    +S +  VV  DVD   +  P+
Sbjct: 317 PFSYPFPFLPVMSGLQLYILHSPFPVLAGAYRSVITGNAISPLLHVV--DVDTGRVVPPY 374

Query: 231 NDLET 235
             L +
Sbjct: 375 ELLSS 379


>UniRef50_Q9TXP3 Cluster: Mtm (Myotubularin) family protein 5; n=1;
           Caenorhabditis elegans|Rep: Mtm (Myotubularin) family
           protein 5 - Caenorhabditis elegans
          Length = 1744

 Score = 50.4 bits (115), Expect = 8e-05
 Identities = 24/60 (40%), Positives = 35/60 (58%)

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           ALL + R+ + +S   RLS C  A  + L+P  + H  + ILP  L + + +P PFLIGV
Sbjct: 199 ALLSDCRIVLASSSLMRLSRCQNAILSLLYPFEYVHSCVTILPDSLAEVLESPTPFLIGV 258


>UniRef50_UPI00006CBEEF Cluster: hypothetical protein TTHERM_00307640;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00307640 - Tetrahymena thermophila SB210
          Length = 1595

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 38/149 (25%), Positives = 68/149 (45%), Gaps = 6/149 (4%)

Query: 53   PCSLEKLLN-CIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAGHSVFTCQCPDS 111
            P +L KL N    N +N   ++ L    E  +I  P   + L++ +N     F+ Q P+ 
Sbjct: 1186 PSALSKLENEFFYNFLNKECKELLE---ELKKIALPSISNRLQLNFNG--ECFSYQVPNR 1240

Query: 112  NKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFP 171
             +   I      +   S+ + +    ++ +LL E+ V  V+S  + LS+ +   ++ L P
Sbjct: 1241 EEAKHIEAEWGCSLVLSSFEKELFVNIFLSLLLEQSVVFVSSNSALLSSTMLLFHSLLKP 1300

Query: 172  MSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
              W H  I  LP +    M  P+P L+G+
Sbjct: 1301 FRWHHPLIFNLPNNFTHLMDIPVPILVGL 1329


>UniRef50_Q7Z401 Cluster: C-myc promoter-binding protein; n=38;
           Tetrapoda|Rep: C-myc promoter-binding protein - Homo
           sapiens (Human)
          Length = 1863

 Score = 50.0 bits (114), Expect = 1e-04
 Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 2/82 (2%)

Query: 145 ERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV 204
           E ++ I + +PS L++  +A  + +FP  W   ++P+ P  L D + AP PF++G+    
Sbjct: 415 EHKILIHSLRPSVLTSVTEALVSMIFPFHWPCPYVPLCPLALADVLSAPCPFIVGIDSRY 474

Query: 205 MENVRMSEIGDVVILDVDANEL 226
            +        DV  +DVD N +
Sbjct: 475 FD--LYDPPPDVSCVDVDTNTI 494


>UniRef50_Q618J0 Cluster: Putative uncharacterized protein CBG14641;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG14641 - Caenorhabditis
           briggsae
          Length = 1690

 Score = 49.6 bits (113), Expect = 1e-04
 Identities = 24/60 (40%), Positives = 35/60 (58%)

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           ALL + R+ + +S   RLS C  A  + L+P  + H  + ILP  L + + +P PFLIGV
Sbjct: 199 ALLSDCRIVLASSSLMRLSRCQNAILSLLYPFVYVHSCVTILPDSLAEVLESPTPFLIGV 258


>UniRef50_A2FP91 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 517

 Score = 49.2 bits (112), Expect = 2e-04
 Identities = 36/135 (26%), Positives = 70/135 (51%), Gaps = 9/135 (6%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPK-- 184
           FS +  K +    +A+L E+R+ +  S    +S+ V +A   + P+ ++  F+P++P   
Sbjct: 276 FSILSVKNVLKFLSAILTEQRIIVYGSDFYNISSVVLSAIPMISPLEYKGAFLPLVPNRA 335

Query: 185 HLVDYMLAPMPFLIGVPRSVMENVRMSEIGD---VVILDVDANELRSPFNDLETLPPELI 241
             +DY+  P+P++ GV +       ++   D   V ++DVD ++L+ P   +  LP    
Sbjct: 336 EFLDYLGTPIPYIFGVLKFDGFLTALNSFVDPSEVCMIDVDNDKLQFP-ESVPILPK--F 392

Query: 242 SSLKKALSDK-NALG 255
           S LK  L ++ N +G
Sbjct: 393 SELKNLLQNQLNQIG 407


>UniRef50_UPI0000D55CBA Cluster: PREDICTED: similar to CG5627-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG5627-PA - Tribolium castaneum
          Length = 1802

 Score = 48.8 bits (111), Expect = 2e-04
 Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 10/181 (5%)

Query: 87  PMPGHT---LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           P+PG T   ++V+  + +       P   +        +L      V+T C+  L   LL
Sbjct: 295 PIPGKTKVYVEVLSPSVYEPLIFALPSHTRFSLADFPLHLPLELLGVET-CLKVLTIILL 353

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLV---DYMLAPMPFLIGV 200
            E +V   +   + L   V A    ++P+ +    IP+LP  +      +LAP P++IG+
Sbjct: 354 -ENKVVFQSRDYNALCMSVMAFVTMIYPLEYMFPVIPMLPTCMSCAEQLLLAPTPYVIGL 412

Query: 201 PRS-VMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNALGDAVS 259
           P S +M         DV ++D+D+N+L S   D+  LP    + LK  L   + L   +S
Sbjct: 413 PASFLMYKKNFKLPDDVWLVDLDSNKLTSS-QDIPPLPEPEGTILKNHLKQVSLLALDIS 471

Query: 260 R 260
           R
Sbjct: 472 R 472


>UniRef50_Q4SLY3 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1814

 Score = 48.4 bits (110), Expect = 3e-04
 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 4/126 (3%)

Query: 101 HSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSA 160
           H       P S+ LP      +L+     +  K  A L    + E ++ + + +P+ L++
Sbjct: 448 HDSLLLSQPVSSPLPL--SGGSLSTLLLNLGPKNAATLLVLAVTEHKILVHSLRPAVLTS 505

Query: 161 CVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILD 220
             +A  + +FP  W   +IP+ P  L D + AP PF++G+     +        D+  +D
Sbjct: 506 VTEALVSMIFPFHWPCPYIPLCPLALADVLSAPCPFIVGMDSRYFD--LYVPPSDITCVD 563

Query: 221 VDANEL 226
           +D N +
Sbjct: 564 LDTNTI 569


>UniRef50_UPI0000498B81 Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 460

 Score = 48.0 bits (109), Expect = 4e-04
 Identities = 51/213 (23%), Positives = 95/213 (44%), Gaps = 19/213 (8%)

Query: 126 YFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKH 185
           +F  V    +  L +A+L ER+V I +     +S  +      + P  ++   I +L   
Sbjct: 235 FFRVVSLSNLLTLISAVLLERKVFIKSEHRCLVSNAISFLIEVIKPFKYEFPIISVLTNK 294

Query: 186 LVDYMLAPMPFLIG---VPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP--PEL 240
           LVD M +P P L+G   VP  + EN  +  I    +       +  P N+  T+    E+
Sbjct: 295 LVDLMDSPTPLLVGCYKVPSELPENSYLYNIDSKTLQCFGEKVIPFPINE-RTINDIKEI 353

Query: 241 ISSLKK--ALSDKNAL---GDAVSRAFLRALV---CLIGGYRDAIKIENGQ----LITFN 288
           +  LK+  A S  N +      +  A  +  V    +   + D     +G     +  F 
Sbjct: 354 LKPLKRYPAHSTSNCILIHSQIIEWAMQKIQVEIRLMFQEFEDYCISSHGSDCNAISLFM 413

Query: 289 PEAFVKT-RKNMQPFLRKILQSQIFQQFIDERL 320
              FV++ +K++QPFL++ +++Q+F+ F  ++L
Sbjct: 414 KNEFVQSQKKDIQPFLKEFVETQMFENFKTKQL 446


>UniRef50_A2ETM8 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 494

 Score = 48.0 bits (109), Expect = 4e-04
 Identities = 35/111 (31%), Positives = 56/111 (50%), Gaps = 8/111 (7%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L +ALL ER + + +S  S ++  + A +A L P++W    I +LP  L+D + +P P +
Sbjct: 301 LLSALLAERTIIVYSSSRSVVANSIYALHAMLLPLNWVSTTISLLPADLMDILDSPAPLI 360

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKAL 248
            G     + + +     D V+L++D  E   P  DL   P    S LKK L
Sbjct: 361 AGETMWPIVSPK-----DAVVLNLDKCEYTFP-KDLVMYP--TASQLKKRL 403


>UniRef50_A2DB21 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 470

 Score = 48.0 bits (109), Expect = 4e-04
 Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 3/91 (3%)

Query: 135 MAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPM 194
           +A + A +L + R+ I++S    L   V +  A L+P+ WQ  FIP+LP   +  + AP 
Sbjct: 183 LASIVATML-DARIIILSSNIELLGQTVFSILALLYPLRWQGTFIPLLPSVALTALEAPF 241

Query: 195 PFLIGVPRSVMENVRMSE-IGDVVILDVDAN 224
            +LIGV  S+M +  + E +    +++VD +
Sbjct: 242 GYLIGV-HSIMASKLLEESVEKYFVMNVDCH 271


>UniRef50_Q54DZ1 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1236

 Score = 47.2 bits (107), Expect = 7e-04
 Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 123  LTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPIL 182
            L+    A+  K +    + +L E+ + + +     +S  V A    L P  +Q  FIP+L
Sbjct: 945  LSGLVKALSLKTLIQAMSCILLEKYLLVTSKNIGTISNSVFAFIPLLKPFIYQGAFIPVL 1004

Query: 183  PKHLVDYMLAPMPFLIGVPRSV--MENVRMSEIGDVVILDVD 222
            P   +D +  P+PF+IG+ +++  + +     + +  +LD+D
Sbjct: 1005 PNSALDALYCPIPFIIGITKNLATLSSEMPDALSNCYVLDID 1046


>UniRef50_UPI00004992B0 Cluster: DENN domain protein; n=1; Entamoeba
           histolytica HM-1:IMSS|Rep: DENN domain protein -
           Entamoeba histolytica HM-1:IMSS
          Length = 396

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 24/91 (26%), Positives = 48/91 (52%), Gaps = 1/91 (1%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+ ++L ERR+ +V S    ++  + +A   + P+SW H  + +LP+   + +  P PF+
Sbjct: 156 LFNSILCERRIIVVGSNYETVTCFILSALELIEPLSWPHPIVTLLPRCYSELVDLPTPFI 215

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRS 228
            G+  +   ++       VV++D+D    RS
Sbjct: 216 CGI-STYQFSLMQPLTNKVVVVDLDNGTTRS 245


>UniRef50_UPI000049905F Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 449

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 25/211 (11%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L +AL+ +R++ I +     LS  +      + P S+    I +L   L D + +P P L
Sbjct: 243 LLSALVLQRKLLIKSKNRCILSGAISFLTQAIKPFSYDSPIISVLINDLFDLIDSPTPLL 302

Query: 198 IG---VPRSVMENVRMSEIGDV--------VILDVDANE-------LRSPFNDLETLPPE 239
           IG   +P  + EN  + +I D          IL  +ANE       +R P  + +  P  
Sbjct: 303 IGCSSLPNEIPENSILYDIDDKFMQKFTDDFILLPNANEIASSIESIRKPLKNCKNHPTH 362

Query: 240 LISSLKKALSDKNALGDAVSRAFLRALVCLIGGYRDAIKIENG--QLITFNPEAFV-KTR 296
               LK+           +   F R +V     Y + +K E G  Q+  F  + F+ +  
Sbjct: 363 F--CLKEHSQYIQWALQKIQIEF-RLMVDNFDDYIETLK-EPGKPQISLFRKKDFIEEAE 418

Query: 297 KNMQPFLRKILQSQIFQQFIDERLDLLNSGR 327
               PFL++  ++Q+F+ FI+E+LD  + G+
Sbjct: 419 PKYLPFLKEFSKTQMFESFINEKLDAYDYGK 449


>UniRef50_A2FCC6 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 518

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 25/76 (32%), Positives = 44/76 (57%), Gaps = 2/76 (2%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILP--K 184
           FS + ++ +     AL+ E+R+ I  +  S +S    A+ A L PMS++   +PI+P   
Sbjct: 280 FSYLSSENIVRYMRALMTEQRIVITGNNISAISMIAIASLAILSPMSYKGSLLPIIPDQD 339

Query: 185 HLVDYMLAPMPFLIGV 200
            L+D++  P+PF+ GV
Sbjct: 340 ELLDFLDTPIPFVFGV 355


>UniRef50_Q68D51-2 Cluster: Isoform 2 of Q68D51 ; n=3;
           Tetrapoda|Rep: Isoform 2 of Q68D51 - Homo sapiens
           (Human)
          Length = 816

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 21/149 (14%)

Query: 213 IGDVVILDVDANELRSPFNDL-ETLPPELISSLKKALSDKN-------------ALGDAV 258
           I +V+I+D+ A++     +D  E LPP+L ++L + L ++N              L   V
Sbjct: 647 IEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLV 706

Query: 259 SRAFLRALVCLIGGYRDAIKI-ENGQLITFNPEAFVK--TRKNMQPFLRKILQSQIFQQF 315
           S AF+R  V L+G Y   + + E G+ + F  E F K  T ++++ FL   +++Q+F  F
Sbjct: 707 SEAFVRFFVELVGHYSLNMTVTERGERV-FQREPFRKSHTSRSVRHFLDLFMETQMFAGF 765

Query: 316 IDERLDLLNSGRGFNDEFEVECNAYADKL 344
           I +R +L  S  G    FE+    Y + +
Sbjct: 766 IQDR-ELRKS--GVKGLFEIRAIQYLETI 791


>UniRef50_Q4DA74 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma cruzi|Rep: Putative uncharacterized protein
           - Trypanosoma cruzi
          Length = 1008

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 4/93 (4%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANAT 168
           PD  + P +  N  L+  F +     +  + + LL ERRV  + + P   SACV +  A 
Sbjct: 278 PDDLRYPFV--NAPLSTLFLSFSYDALRVIHSLLLQERRVVFIGATPQHASACVVSVQAM 335

Query: 169 LFPMSWQHIFIPILPKHLVDYM--LAPMPFLIG 199
           L P  W    +P +P    + +  L    F++G
Sbjct: 336 LSPFIWTLPIVPYMPPEACEILEALGDSGFILG 368


>UniRef50_A4H3X7 Cluster: Putative uncharacterized protein; n=2;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania braziliensis
          Length = 1611

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 22/49 (44%), Positives = 28/49 (57%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           L + LL E RV ++ S P   SACV +  A L P++W    IP LP HL
Sbjct: 475 LQSLLLQEARVVVLGSTPQHASACVVSLLALLGPLTWVSPLIPYLPPHL 523


>UniRef50_A0D955 Cluster: Chromosome undetermined scaffold_41, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_41,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 744

 Score = 45.6 bits (103), Expect = 0.002
 Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 2/93 (2%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           ++ E ++ IV+ KP+ ++   Q+    L P+ W+ +FIP L     D+  + +P++IG+ 
Sbjct: 266 MMLEYQIIIVSRKPAGITLFCQSLVELLAPLQWRGLFIPFLRPGSFDFHKSQLPYIIGLD 325

Query: 202 RSVMENVRMSEIGDV--VILDVDANELRSPFND 232
           R++ E        ++  VI D+D   + S  +D
Sbjct: 326 RNLYEISEKPLPKELKRVIYDIDDGRILSRSDD 358


>UniRef50_UPI00006CAAB7 Cluster: DENN (AEX-3) domain protein; n=1;
            Tetrahymena thermophila SB210|Rep: DENN (AEX-3) domain
            protein - Tetrahymena thermophila SB210
          Length = 1711

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 21/80 (26%), Positives = 43/80 (53%)

Query: 127  FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
            FS +  +    ++  +L E+ +  V++ P+ LS+ +    + + P  W H  I ILP++L
Sbjct: 1403 FSCIAYETFIEIFFNILIEQPMVFVSANPALLSSVILMFYSLIKPFKWPHPLISILPQNL 1462

Query: 187  VDYMLAPMPFLIGVPRSVME 206
            +  + +P+P  +G+  S  E
Sbjct: 1463 IHLLDSPIPIFLGLNMSKQE 1482


>UniRef50_UPI00005841BF Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 200

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 32/139 (23%), Positives = 64/139 (46%), Gaps = 5/139 (3%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANAT 168
           PD  + P +  N +L   F       +  + +A+L ++R+  ++   S L   ++   + 
Sbjct: 12  PDDPEKPVV--NISLHLPFLCFSLDDILKIISAILTQQRLIFLSHDYSLLVPIIECFFSY 69

Query: 169 LFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS 228
           + P  W  +++P++   L+D + AP  F++G   S     R+ +I  +VI D++   L  
Sbjct: 70  ILPFKWPFVYVPVVCTQLLDLLEAPGCFIMGCHSS--HRSRIQQIEGLVIADIEKGTLHE 127

Query: 229 -PFNDLETLPPELISSLKK 246
            P   + +LP       KK
Sbjct: 128 CPTLSVPSLPKAPAEGFKK 146


>UniRef50_Q9D5B9 Cluster: Adult male testis cDNA, RIKEN full-length
           enriched library, clone:4930467M19 product:SAM domain,
           SH3 domain and nuclear localisation signals, 1, full
           insert sequence; n=1; Mus musculus|Rep: Adult male
           testis cDNA, RIKEN full-length enriched library,
           clone:4930467M19 product:SAM domain, SH3 domain and
           nuclear localisation signals, 1, full insert sequence -
           Mus musculus (Mouse)
          Length = 499

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 32/87 (36%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 291 AFVKTRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQ 350
           A +K R ++          +I   FID RL  LN+GRGF+D FE E        + G   
Sbjct: 73  ASLKLRAHLITMFAWSFLHRILPMFIDGRLAKLNAGRGFSDIFEEEIT------SGGFCG 126

Query: 351 KLKQQYRDWAKTVKKEGGAFFKTVKDK 377
              + Y+ W  TVKK GGA F T   K
Sbjct: 127 GSPRSYQQWVYTVKK-GGALFNTAVTK 152


>UniRef50_A2DP70 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 459

 Score = 45.2 bits (102), Expect = 0.003
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 5/100 (5%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKH- 185
           FS   TK +  L +  L + R+  V      ++  V A +  L P+ +    +PILP + 
Sbjct: 230 FSIFPTKSILTLISCALCDHRIVFVGKSLQNITMSVTALSHLLRPLKFSGAVVPILPANP 289

Query: 186 -LVDYMLAPMPFLIGVPR-SVMENVRMSEIGDVVILDVDA 223
             +  + AP P++IGVPR  ++ +V + +   V++ D D+
Sbjct: 290 SYITLLEAPTPYIIGVPRCDLLPSVDVDD--GVILADTDS 327


>UniRef50_UPI0000499718 Cluster: hypothetical protein 43.t00023;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 43.t00023 - Entamoeba histolytica HM-1:IMSS
          Length = 483

 Score = 44.8 bits (101), Expect = 0.004
 Identities = 36/176 (20%), Positives = 70/176 (39%), Gaps = 7/176 (3%)

Query: 28  PYVLFKYPE-SYKNEEEIKSIPKFTFPCSLEKLLNCIANIINSPERDQLHSFLEACRIRP 86
           PY L  +P   Y  E   ++  ++ +   L +L     N+  +P +  L +F+      P
Sbjct: 142 PYFLALFPLLHYIAEHSYRNKLEYFYSVVL-RLTLLSPNVCLNPIKPSLEAFIHLIFRIP 200

Query: 87  PMPGHTLKVIYNAGHSVFTCQCPDSNKLP-----SIPDNCNLTEYFSAVDTKCMAGLWAA 141
               + L          F    P     P     S+  + +L   F  +  + +  + + 
Sbjct: 201 QKQSNPLSFTIENNKYTFARSSPPLPSTPLSQSMSLVGDYSLIRLFCTMSVEEILNILSV 260

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           +L    V +++   S  ++C+    A  +P +W  IFIP +P  L ++   P+P L
Sbjct: 261 MLCGMGVILISENISTATSCIFGFLALFYPFTWPGIFIPYIPDELFEFYETPVPIL 316


>UniRef50_A2E7C4 Cluster: UDENN domain containing protein; n=2;
           Trichomonas vaginalis G3|Rep: UDENN domain containing
           protein - Trichomonas vaginalis G3
          Length = 510

 Score = 44.4 bits (100), Expect = 0.005
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 19/124 (15%)

Query: 115 PSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSW 174
           P++P  C LT + S V+   +  L+ ALL +  + I +  P R S CV AA+  + P   
Sbjct: 268 PTLP--CLLT-HLSTVN---IVKLYTALLLDYHILIYSKYPERYSNCVIAASMLVKPFMS 321

Query: 175 QHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDV-VILDVDANELRSPFNDL 233
               +P+LP    + +  P PF+ G          M +  DV VI+DVD NE+ S   +L
Sbjct: 322 ITTIMPVLPLSFNEVLGTPTPFIYG----------MGQKFDVDVIVDVDKNEIIS--QEL 369

Query: 234 ETLP 237
             LP
Sbjct: 370 PVLP 373


>UniRef50_UPI0000499FB9 Cluster: hypothetical protein 56.t00003;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 56.t00003 - Entamoeba histolytica HM-1:IMSS
          Length = 646

 Score = 44.0 bits (99), Expect = 0.007
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)

Query: 123 LTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPIL 182
           L   F  V    +    ++LL    V +V +  S +++ V      L+P  WQ + IP +
Sbjct: 260 LPRLFVGVQIPVILSALSSLLSGNSVILVGNNASLITSSVFGLLTLLYPFIWQGVLIPFV 319

Query: 183 PKHLVDYMLAPMPFLIG--VPRS---VMENVRMSEIGDV 216
           P  L +++ +P+P L G  +P+    VM +V   E G V
Sbjct: 320 PVQLQEFLESPVPSLYGTEIPKDITRVMADVIQLEQGSV 358


>UniRef50_UPI000066125D Cluster: UPI000066125D related cluster; n=1;
           Takifugu rubripes|Rep: UPI000066125D UniRef100 entry -
           Takifugu rubripes
          Length = 431

 Score = 44.0 bits (99), Expect = 0.007
 Identities = 26/85 (30%), Positives = 42/85 (49%), Gaps = 6/85 (7%)

Query: 169 LFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANEL-- 226
           +FP  WQ  ++P+ P  L   + AP+PF++GV     +        DVV +D+D N +  
Sbjct: 2   IFPFQWQCPYVPLCPLSLAGVLNAPLPFIVGVDSRYFD--LYDPPPDVVCVDLDTNTVYL 59

Query: 227 --RSPFNDLETLPPELISSLKKALS 249
                 N+ + LP +   SL  +LS
Sbjct: 60  SDEKRHNNWKNLPKKPCKSLIGSLS 84


>UniRef50_Q54JN1 Cluster: DENN domain-containing protein; n=1;
           Dictyostelium discoideum AX4|Rep: DENN domain-containing
           protein - Dictyostelium discoideum AX4
          Length = 712

 Score = 44.0 bits (99), Expect = 0.007
 Identities = 37/159 (23%), Positives = 75/159 (47%), Gaps = 12/159 (7%)

Query: 130 VDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPK----- 184
           V  K +  +  A+L E++V   +     L++ +    + L P ++Q + +P+LP      
Sbjct: 476 VQPKILIVILNAILLEKKVIFYSKTIRSLTSVIFTVLSLLSPFNYQSVILPLLPNSVSSL 535

Query: 185 HLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP--PELIS 242
            +VD + AP+P++IG+   V ++V   +  D+V  D+D  +L+     +   P   +L++
Sbjct: 536 SIVDLLSAPVPYIIGL-TDVPKDV---DYSDIVQYDIDTGKLQQGNQKIMLFPHWQDLLN 591

Query: 243 SLKKALSD-KNALGDAVSRAFLRALVCLIGGYRDAIKIE 280
            L  A  D K +L    ++ F       I      +K++
Sbjct: 592 VLTIAQKDIKTSLTVNKNKGFSSPTTSFIPTEEQELKLQ 630


>UniRef50_UPI000049A5D5 Cluster: hypothetical protein 405.t00005;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 405.t00005 - Entamoeba histolytica HM-1:IMSS
          Length = 484

 Score = 43.6 bits (98), Expect = 0.009
 Identities = 18/73 (24%), Positives = 41/73 (56%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F+ +    +  L+ ++L E  V + +++P+  +A      + L P+SWQ +F+P++P   
Sbjct: 259 FTTLPLNIILDLFESILLETSVILTSTRPTLFTAGCFGLLSLLHPLSWQGVFLPMVPHSH 318

Query: 187 VDYMLAPMPFLIG 199
           ++ +  P+P + G
Sbjct: 319 IELLDVPVPGIFG 331


>UniRef50_Q95Z85 Cluster: Putative uncharacterized protein L3291.04;
           n=1; Leishmania major|Rep: Putative uncharacterized
           protein L3291.04 - Leishmania major
          Length = 1565

 Score = 43.2 bits (97), Expect = 0.012
 Identities = 18/49 (36%), Positives = 28/49 (57%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           L + L+ E RV ++ + P   SACV +  A + P++W    +P LP HL
Sbjct: 435 LLSLLMQEERVVVLGATPQHASACVVSLLALMSPLTWVSPLVPYLPPHL 483


>UniRef50_A2G8A8 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 507

 Score = 42.7 bits (96), Expect = 0.016
 Identities = 31/130 (23%), Positives = 65/130 (50%), Gaps = 8/130 (6%)

Query: 128 SAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPK--H 185
           S ++ K +  + +AL  + ++ ++ S    +S  V A    + PM +  I +P+LP+   
Sbjct: 249 SILEPKMILDVLSALYLDYQILVIGSCLEEVSLTVLAFVHLIDPMKYSGIVMPVLPQTDD 308

Query: 186 LVDYMLAPMPFLIG-VPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLP--PELIS 242
            +D + AP P++IG +P   +  +++  +   V +++D   + +   D+   P    +  
Sbjct: 309 YLDILQAPTPYIIGTIPSDKL--LKLDFLDTTVFVNLDTKTVETG-EDMPHYPNAENIAK 365

Query: 243 SLKKALSDKN 252
            LKK  S+KN
Sbjct: 366 ELKKEFSEKN 375


>UniRef50_A2DZM1 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 476

 Score = 42.7 bits (96), Expect = 0.016
 Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 5/135 (3%)

Query: 120 NCNLTE-YFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIF 178
           NC + + +FS++  + +  L  ALL +R++ +  S   ++S  V +    + P+++    
Sbjct: 208 NCAIFDTFFSSLTIENIISLVTALLLDRQIVVFGSNFQQVSLVVLSLLQLIHPVNYVGTA 267

Query: 179 IPILP--KHLVDYMLAPMPFLIGVPR-SVMENVRMSEIGDVVILDVDANELRSPFNDLET 235
           IP LP   + +  + AP PF+IG      + N+   E    V +D    E  +P  +  +
Sbjct: 268 IPALPNSSNYLTLLEAPTPFIIGCKTCDQLTNIEFDETAVFVNMDARQIEFVTPLPNYPS 327

Query: 236 LPPELISSLKKALSD 250
               ++  LK+ +S+
Sbjct: 328 -SESILRKLKRLVSN 341


>UniRef50_A2E9J8 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 554

 Score = 41.5 bits (93), Expect = 0.036
 Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 123 LTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPIL 182
           L   FS + T  +  L+ A++ E  + ++  KPS  S C+ A  + + P+       PIL
Sbjct: 261 LDSLFSHLSTYNIVKLFTAVVLEHIIIVITDKPSLASNCILALRSLVHPLKILSPISPIL 320

Query: 183 P-KHLVDYML-APMPFLIGVPRSVMENVRMSEIGD-VVILDVD 222
           P K   + +L  P P + GV ++   N+ +SE  D   I+D+D
Sbjct: 321 PAKPKYEAILGCPSPIICGVLKN--PNLDLSETCDEKCIVDID 361


>UniRef50_A0EFY5 Cluster: Chromosome undetermined scaffold_94, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_94,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 557

 Score = 41.1 bits (92), Expect = 0.048
 Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 11/134 (8%)

Query: 108 CPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPS-RLSACVQAAN 166
           C + N L  IP      + F  ++++ +  ++ + L E+ +  V+  P    +AC+    
Sbjct: 322 CENDNILWGIP------QLFKKLNSQSLIKIFVSCLIEKSIVFVSKSPQLSTAACLLCQK 375

Query: 167 ATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP---RSVMENVRMSEIGDVVILDVDA 223
             L P +W H  I  LP   + Y+ +P+P + G+     ++     + +  + + +++D 
Sbjct: 376 YLLKPFAWIHPIISNLPLENIVYLGSPVPIIAGLECNFSTLQSQGLIDKFQNTIFINLD- 434

Query: 224 NELRSPFNDLETLP 237
           ++L+  F + + +P
Sbjct: 435 SKLQIQFGNTDAIP 448


>UniRef50_A0E249 Cluster: Chromosome undetermined scaffold_74, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_74,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 783

 Score = 41.1 bits (92), Expect = 0.048
 Identities = 58/275 (21%), Positives = 115/275 (41%), Gaps = 16/275 (5%)

Query: 72  RDQLHSFLEACRIRPPMPGHT-LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAV 130
           +D+L  FL   +   PM GH  L+V   AG   +  + P+  +L       +       +
Sbjct: 474 QDELTKFLNLIQAIRPMLGHQQLEVQTLAGTLKY--RIPNQLQLDIELRLWSANVTLQIL 531

Query: 131 DTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYM 190
           + K +  ++ A++ E  +  V  K + L++ +   +  + P+ W    I  +P+ L+  +
Sbjct: 532 NYKEILNIFLAMISEISIIFVCEKSNILTSIIHFFHHIVRPLEWTQGIIYNVPEQLLTMI 591

Query: 191 LAPMPFLIGVPRSVMENVRMS-----EIGDVVILDVDANE--LRSPFNDLETLPPELISS 243
            +P+P +IGV  +  +   MS     E    V LD D     L  P N L+ +       
Sbjct: 592 QSPVPIIIGVNLTESDFNLMSLADNCENHLFVFLDRDKENKFLPKPQNVLKDISSPSFGG 651

Query: 244 LKKALSD--KNALGDAVSRAFLRALVCLIGGYRDAIKIENGQLIT---FNPEAFVKTRKN 298
           L + +    KN+      R  L   + L    R      + + +    F+ +   K++K 
Sbjct: 652 LLQHIETILKNSNNMRNPRQMLMRSLLLSPSIRQVSNKNDDRKVVKFYFDDQDQSKSKKV 711

Query: 299 MQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEF 333
           ++ F +KI++  I  +   +  D +  G+  N ++
Sbjct: 712 LETF-KKIMEEYIISKLPPQNEDAIKVGQDLNFQY 745


>UniRef50_UPI0000499593 Cluster: hypothetical protein 43.t00017;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
           protein 43.t00017 - Entamoeba histolytica HM-1:IMSS
          Length = 452

 Score = 40.7 bits (91), Expect = 0.063
 Identities = 16/60 (26%), Positives = 33/60 (55%)

Query: 140 AALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIG 199
           ++LL    V ++    S ++ CV A    + P  W+ + +P +P HL +++ +P+P + G
Sbjct: 236 SSLLLNVSVFLIGKNVSLVTDCVLALLPLIQPFQWEGVVLPYIPSHLYEFLESPIPSIYG 295


>UniRef50_Q245U2 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1032

 Score = 40.7 bits (91), Expect = 0.063
 Identities = 16/63 (25%), Positives = 34/63 (53%)

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           A+L E+ +  V++    L+  +    A + P  W +  +  LP++L+  + +P P ++G+
Sbjct: 799 AILQEQHIIFVSTNLCLLTKAIACFEALIMPFQWPYPIVYTLPENLMGLLGSPQPIILGI 858

Query: 201 PRS 203
            RS
Sbjct: 859 NRS 861


>UniRef50_UPI00006CB637 Cluster: hypothetical protein TTHERM_00444640;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00444640 - Tetrahymena thermophila SB210
          Length = 1424

 Score = 40.3 bits (90), Expect = 0.083
 Identities = 19/63 (30%), Positives = 31/63 (49%)

Query: 141  ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
            +LL E  +  ++  PS LS  +    + L P  W H F+  L   L+    +P P +IG+
Sbjct: 1218 SLLLEESLVFLSKNPSTLSQTMMMFMSALKPFKWPHPFVMFLSNDLMHMFDSPFPLVIGI 1277

Query: 201  PRS 203
             +S
Sbjct: 1278 NKS 1280


>UniRef50_A2FDU6 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 497

 Score = 39.9 bits (89), Expect = 0.11
 Identities = 39/186 (20%), Positives = 76/186 (40%), Gaps = 15/186 (8%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L + LL E   A+V +    +S         + P  W    I ILPK L+  + +P+P +
Sbjct: 279 LLSFLLLENYFAVVGTNIEAISKITTVLPQLILPFFWTSPVISILPKDLLALLDSPVPTI 338

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPP-ELISSLKKALSDKNALGD 256
           +G    +    R       VI+D+D   +  P   +  LP  + + ++   + +   +  
Sbjct: 339 LG----IYSKFRKLIPSHYVIIDIDKKHISYPNEPMLKLPKHKFLRNMLAPIYEAGQMNV 394

Query: 257 AVSRAFLRAL---------VCLIGGYRDAIKIENGQLITFNPEAFVKT-RKNMQPFLRKI 306
            +++  LR +           +I      +  +N +   + P+ F     K   PFL+K+
Sbjct: 395 GIAQNILRIISEFIIDTIVKQVISALITKVNEKNTEGTMYLPDLFYSVFDKEDLPFLKKM 454

Query: 307 LQSQIF 312
            ++Q F
Sbjct: 455 NETQYF 460


>UniRef50_UPI00004990AD Cluster: conserved hypothetical protein;
           n=2; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 955

 Score = 39.5 bits (88), Expect = 0.15
 Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 6/145 (4%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANAT 168
           P  + LP    N ++   FS  +   M  L+  L+   ++ I +S  S L+  +    + 
Sbjct: 392 PVKHSLPVF--NTSIYPLFSIFNVSGMTTLFLLLMTNLKIVIFSSHLSLLTTSIDNLISL 449

Query: 169 LFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRS 228
           L+P         ILP   ++ +     F+ GVP    E +   ++G+   +DVD +    
Sbjct: 450 LYPFPPTQKVFAILPYKNLNVLSGSDTFIAGVPSEYRE-IAKKQLGNEEYIDVDLDTGII 508

Query: 229 PFN---DLETLPPELISSLKKALSD 250
             N   +L   P +L   L+K L+D
Sbjct: 509 EMNVSKELLEFPVDLTVDLQKDLND 533


>UniRef50_UPI0000E45EF0 Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 188

 Score = 38.7 bits (86), Expect = 0.25
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 21/125 (16%)

Query: 216 VVILDVDANELRSPFNDLET-LPPELISSLKKALS------------------DKNALGD 256
           V+++D+DA +  +   D  T LP +L ++L++AL                   D  +   
Sbjct: 1   VLVVDLDAKDFYTVIGDEGTILPKKLSAALERALKVCSMSSWEGADTDDELSEDHESKNS 60

Query: 257 AVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVK--TRKNMQPFLRKILQSQIFQQ 314
           A+S AF+R  V  +G Y +           F+ E+F+K  + K+++ FL    ++Q+F  
Sbjct: 61  AISEAFIRFFVETVGHYSNHFTQAYDDSQKFDRESFIKAVSSKSVRNFLEVFSETQMFSL 120

Query: 315 FIDER 319
           FI E+
Sbjct: 121 FIQEK 125


>UniRef50_Q22ZG4 Cluster: DENN (AEX-3) domain; n=1; Tetrahymena
           thermophila SB210|Rep: DENN (AEX-3) domain - Tetrahymena
           thermophila SB210
          Length = 934

 Score = 38.7 bits (86), Expect = 0.25
 Identities = 33/161 (20%), Positives = 71/161 (44%), Gaps = 7/161 (4%)

Query: 109 PDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANAT 168
           P  N++  I          S +  +    ++ A+  E+++   +S  S L++ +    + 
Sbjct: 665 PAQNRIVQIETEWGACLAMSCLPLEDFLFIFTAIALEKKMIFFSSNKSLLTSVILTFYSI 724

Query: 169 LFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPR--SVMENVRMS--EIGDVVILDVDAN 224
             P ++    I  LP  ++  + AP+PF+IG+ +  S  + +  S  ++ D +I+D+D  
Sbjct: 725 YKPFTYVFPVIFNLPVEMLGMLDAPVPFIIGINKDSSFKDELEQSGNDLSDKLIVDLDRQ 784

Query: 225 EL---RSPFNDLETLPPELISSLKKALSDKNALGDAVSRAF 262
            +       N +E   P+ IS  K+ + +   +    S  F
Sbjct: 785 VIICTDESSNQVEKNIPQFISRQKEIIENYYLINPRSSNRF 825


>UniRef50_Q9M9A7 Cluster: F27J15.16; n=1; Arabidopsis thaliana|Rep:
           F27J15.16 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 931

 Score = 38.3 bits (85), Expect = 0.34
 Identities = 50/194 (25%), Positives = 87/194 (44%), Gaps = 44/194 (22%)

Query: 162 VQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRSV-MENVRMSEIGDVVILD 220
           V+A      P + Q ++IP+L    VDY+ AP P+++G+   V   N+ M     VV++D
Sbjct: 216 VEAPPEDSLPQADQ-VYIPLLFFSGVDYIDAPTPYMMGLHSDVDTSNLAMD---GVVVVD 271

Query: 221 VDANELRS-------PFNDLETLPPELISSLKK---ALSDKNALGDAVSRA--------- 261
           +D N++ +       P  +  TL  +++  L     A+      G++V +          
Sbjct: 272 LDINQITTSEEIPQIPEPEFSTLRNDILKLLHPNVVAIDQLKGFGNSVEQCPKSLSKPWG 331

Query: 262 ----------FLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNM-----QPFLRKI 306
                     FL+    ++GGYR+   IEN     F+ +AF+K R        +P L + 
Sbjct: 332 EDHDLQLRVIFLKCFASILGGYRNF--IENK---VFSTDAFLKRRSRSTNQPPEPMLVQF 386

Query: 307 LQSQIFQQFIDERL 320
           L S  F  +++ RL
Sbjct: 387 LGSFAFLDYLERRL 400


>UniRef50_A0DZU7 Cluster: Chromosome undetermined scaffold_70, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_70,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 713

 Score = 38.3 bits (85), Expect = 0.34
 Identities = 24/132 (18%), Positives = 61/132 (46%), Gaps = 3/132 (2%)

Query: 120 NCNLTEYFSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFI 179
           N      FS +    +  +   ++ E+++   ++  S +    +   + + P+ W +I+I
Sbjct: 289 NFTFRPLFSRLSLVNIMRIVMCIISEKQMVFFSTNISEIPQITEGLLSLIKPLKWSNIYI 348

Query: 180 PILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETL--P 237
           P     + +Y  A  P++IG  +   +   ++++   VI+D+D + +    + ++ L  P
Sbjct: 349 PCSNIDIWEYAQALQPYIIGFEKK-HKQFLLTQLQGKVIVDLDEDSIIDNSHTIDDLKIP 407

Query: 238 PELISSLKKALS 249
            + +  LK  L+
Sbjct: 408 EKWLIELKNKLN 419


>UniRef50_Q9FJA0 Cluster: Gb|AAD21756.1; n=3; Arabidopsis
           thaliana|Rep: Gb|AAD21756.1 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 722

 Score = 37.9 bits (84), Expect = 0.44
 Identities = 13/44 (29%), Positives = 28/44 (63%)

Query: 158 LSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           L+A V +    + P  WQ + +P+LP  +++++ AP+P+++  P
Sbjct: 558 LAASVLSIIPVIRPFRWQSLLMPVLPDDMLEFLDAPVPYIVKSP 601


>UniRef50_A2DC37 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 474

 Score = 37.9 bits (84), Expect = 0.44
 Identities = 42/194 (21%), Positives = 91/194 (46%), Gaps = 16/194 (8%)

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           +LL E+R+ I +S  + +S  + AAN  ++P+        ++P    + +     F++G+
Sbjct: 286 SLLLEKRIIISSSNITSVSLIILAANLMIYPLKLSVPTFSVIPISKFEKLKEKKSFVVGI 345

Query: 201 PRSVMENVRMSEIGDVVILDVDANE--LRSPFNDLETLPPELISSLKKALSDKNALGDAV 258
              + +        D + ++V   E  ++S F++     PE I  +K+ L D N   DA 
Sbjct: 346 TEELTDIP-----DDCLYINVHGEESSMKSSFSEEIPKLPE-IEKIKQNLED-NLWFDAD 398

Query: 259 SRAFLRA--LVCLIGGYRDAI--KIEN--GQLITFNPEAFVK-TRKNMQPFLRKILQSQI 311
            +  +    L+  + GY   I   +E+   +   F  E F     +  +PF+  +++++I
Sbjct: 399 KKRNVACAQLLDFLTGYIRGILMPVEDCFDENFDFELETFESFFMEESKPFIDSLIKTKI 458

Query: 312 FQQFIDERLDLLNS 325
           F+ ++D   ++ +S
Sbjct: 459 FKNYVDYMKNIQSS 472


>UniRef50_A0CCY9 Cluster: Chromosome undetermined scaffold_169,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_169,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 870

 Score = 37.9 bits (84), Expect = 0.44
 Identities = 46/188 (24%), Positives = 85/188 (45%), Gaps = 17/188 (9%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           L+ A+L ER++ + +S        ++A    ++P+ +Q + I  L       +  P P++
Sbjct: 410 LYTAVLTERKIRLCSSSILNPGYVIEALMTFIYPLQYQKLLICYLNYDNSQIIETPEPYI 469

Query: 198 IGVPRSVMENVRMSEIGDVVILD--VDANELRSP-FNDLETLPPELISSLKKALSDKNAL 254
           +G+P ++ +    SE G   ILD  V  N    P F   E L  +L    ++ +++ NA 
Sbjct: 470 VGLPETLPQPACESE-GYKFILDYNVAYNVCPPPEFPLFEKLKKKLEPFARQDINETNA- 527

Query: 255 GDAVSRAFLRA-LVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQP----FLRKILQS 309
            + +   FL+  L  L   +   IK +N  +      AF K +++  P    F     ++
Sbjct: 528 -NLIKGIFLKINLKILSHAFDYDIKQKNWSI------AFQKKKQSQYPIKGQFWEIFSRT 580

Query: 310 QIFQQFID 317
           Q+   FID
Sbjct: 581 QLLCSFID 588


>UniRef50_A2G1U2 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 490

 Score = 37.5 bits (83), Expect = 0.59
 Identities = 21/63 (33%), Positives = 32/63 (50%)

Query: 138 LWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFL 197
           +++AL  ER + I     S +   V A +  L P  W    I  LPK L D++ +P P +
Sbjct: 293 IYSALCLERTIIIYHPTISIVCNFVMACHFILRPFRWAGSSIAPLPKSLNDFLNSPTPII 352

Query: 198 IGV 200
           IG+
Sbjct: 353 IGI 355


>UniRef50_Q236Q2 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 953

 Score = 37.1 bits (82), Expect = 0.78
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 2/89 (2%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVP 201
           L  E +V I +SK S  +   +   + + PM+W+ ++ P       DY     PFL+G+ 
Sbjct: 332 LFLEYQVVITSSKQSTSTLFCENLLSLIKPMNWKGLYYPTQMNSGFDYQKCFQPFLVGIQ 391

Query: 202 RSVMENVR--MSEIGDVVILDVDANELRS 228
           +   + +     +  + VI D+D N   S
Sbjct: 392 KKSEDGLERFQKQPKNRVIYDLDENNFIS 420


>UniRef50_A2DXN2 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 508

 Score = 37.1 bits (82), Expect = 0.78
 Identities = 31/171 (18%), Positives = 73/171 (42%), Gaps = 9/171 (5%)

Query: 87  PMPGHTLKVIYNAGH-SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALLHE 145
           P+   T+ + +N  +   F  + P   ++   P         S +       L  +++  
Sbjct: 219 PVFDETIAIRFNYSNVPPFAWKMPKREEIAYSPSAVGYDLIMSWISVDQYIRLLESIMLG 278

Query: 146 RRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV----- 200
             V ++    + ++  V      + P  W  + +  +P+ +++Y+ +P+P++ G      
Sbjct: 279 SYVLVIGDNFANITKTVSFLPTIIMPFIWTSVIVSFVPESMLEYLDSPVPYIYGAFTKNI 338

Query: 201 -PRSVMENVRMSEIGDVVILDVDANELRSP-FNDLETLPPELISSLKKALS 249
             R++ EN  +  I D   LD    E++ P + DL++   + I+ LK  ++
Sbjct: 339 KGRNINENTVVVYI-DEKRLDFPPTEIKIPGYLDLKSKLEQPINHLKTKMN 388


>UniRef50_A0EC60 Cluster: Chromosome undetermined scaffold_89, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_89,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 606

 Score = 37.1 bits (82), Expect = 0.78
 Identities = 20/74 (27%), Positives = 37/74 (50%)

Query: 127 FSAVDTKCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHL 186
           F  +  K +  L + +L  +RV + + K S LS  +    + + P +++  F   +P  L
Sbjct: 354 FQTLSFKELVYLISHVLLSQRVILFSKKKSVLSHVMLTVISLMHPFNYKLPFCIFIPDEL 413

Query: 187 VDYMLAPMPFLIGV 200
           +D + AP P+  GV
Sbjct: 414 IDRLAAPCPYFFGV 427


>UniRef50_A2ENJ0 Cluster: Putative uncharacterized protein; n=1;
           Trichomonas vaginalis G3|Rep: Putative uncharacterized
           protein - Trichomonas vaginalis G3
          Length = 654

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV- 200
           +L  R +  ++   S+LS  V A    + P  W    IP+LP  L D    P+P +IG+ 
Sbjct: 167 MLEARHIFPISLNLSKLSRAVAALPLLIEPFRWNMNQIPVLPIALKDATNIPVPTMIGIS 226

Query: 201 -PRSVMENVRMSEIGDVVILDVDANELRSPFN 231
            P  ++E    + I  +V LD        PFN
Sbjct: 227 DPTILLEGRIDNHI--LVNLDTFCVVENPPFN 256


>UniRef50_Q8SS14 Cluster: CYCLIN B-LIKE GUANINE NUCLEOTIDE BINDING
           PROTEIN; n=1; Encephalitozoon cuniculi|Rep: CYCLIN
           B-LIKE GUANINE NUCLEOTIDE BINDING PROTEIN -
           Encephalitozoon cuniculi
          Length = 685

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 43/192 (22%), Positives = 83/192 (43%), Gaps = 17/192 (8%)

Query: 133 KCMAGLWAALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIF-IPILPKHLVDYML 191
           K +  + + +L E R+   ++K S L   V      + P  W HI  +P+LP  + + + 
Sbjct: 247 KFLLKVLSLILLEERIVFYSAKSSSLR--VLQIMELIKPFRWPHIICLPLLPG-MEEILE 303

Query: 192 APMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDK 251
           +P+PF+  + R +       + GDVV +D+D  +L+   +  + L P   +    A    
Sbjct: 304 SPLPFVTCLDRKL-------KAGDVVFVDLD--DLKIHSSKRQALLPNKKAKDTAAQGHM 354

Query: 252 NALGDAVSRAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQPFLRKILQSQI 311
             + D +    +   + L   Y   IK    ++I   P   ++  +  + F     ++++
Sbjct: 355 EEMKDCIE--MIATEILLWREY--LIKRHGSRVIAKMPNNPLEFTRKARGFYSDFFRTRM 410

Query: 312 FQQFIDERLDLL 323
           F  FI E  D L
Sbjct: 411 FLAFITEEHDHL 422


>UniRef50_A6RXE1 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 936

 Score = 36.3 bits (80), Expect = 1.4
 Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 7/117 (5%)

Query: 113 KLPSIP---DNCNLTEYFSAVDTKCMAG-LWAALLHERRVAIVASKPSRLSACVQAANAT 168
           + PS P    N  +   FS +    + G + AAL   RR+  V+  P+ L+   +     
Sbjct: 271 QFPSSPTGFQNFAMWPLFSCLSIPNIVGVIEAALSPTRRIIFVSHYPAMLTVASETIRYF 330

Query: 169 LFPMSWQHIFIPIL-PKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDAN 224
           +    W  +++P++  +H  + +  P P+++G+          +   D +++D+D N
Sbjct: 331 VRVYEWSGLYVPVVHARHAQELVQEPGPYILGITAECRS--LFTAPTDALVVDLDRN 385


>UniRef50_A0GXF2 Cluster: Sensor protein; n=2; Chloroflexus|Rep:
           Sensor protein - Chloroflexus aggregans DSM 9485
          Length = 1352

 Score = 35.9 bits (79), Expect = 1.8
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 202 RSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNALGDAVSRA 261
           R+  E  R   + D  + ++ ++ELR+P N + TL   L+  L+  L+++      +   
Sbjct: 840 RANAELARSVRVKDEFLANM-SHELRTPLNTILTLSESLLEELRGPLNERQRASIQLIET 898

Query: 262 FLRALVCLIGGYRDAIKIENGQL 284
             R L+ LI    D  KIE G++
Sbjct: 899 SGRHLLTLINDVLDVAKIEAGRM 921


>UniRef50_Q22ZD3 Cluster: Putative uncharacterized protein; n=2;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 853

 Score = 35.9 bits (79), Expect = 1.8
 Identities = 40/156 (25%), Positives = 73/156 (46%), Gaps = 19/156 (12%)

Query: 142 LLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPM--PFLIG 199
           +L ER + I +S P  +    ++    + P++  +I++P    H + ++L  +    +IG
Sbjct: 343 ILLERFILIFSSSPGEIPCLTESILKLIQPLNHINIYVPFASLHHL-WLLESLGTSAIIG 401

Query: 200 VPRSVMENVRMSEIGD-VVILDVDANEL-RSPFNDLETLPPE----LISSLKKA------ 247
             + +     +   G  VVI+D+DAN +    F +++ LP +    +I  L KA      
Sbjct: 402 FSKILERLNEIDRAGKIVVIVDLDANTIEEDTFLNIQ-LPSKAKGYIIKELTKAEYEYKQ 460

Query: 248 LSDKNALGDAV---SRAFLRALVCLIGGYRDAIKIE 280
             +KNA    V   SR+F   ++CL+  Y    K E
Sbjct: 461 SREKNAWEKTVIEISRSFFNFILCLVNDYTQFYKQE 496


>UniRef50_Q17L72 Cluster: Map-kinase activating death domain protein
           (Madd)/denn/aex- 3; n=1; Aedes aegypti|Rep: Map-kinase
           activating death domain protein (Madd)/denn/aex- 3 -
           Aedes aegypti (Yellowfever mosquito)
          Length = 1938

 Score = 35.9 bits (79), Expect = 1.8
 Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 7/131 (5%)

Query: 87  PMPGHT---LKVIYNAGHSVFTCQCPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           P+PG T   ++++    H       PD  +   +    +L      VDT C+  L   LL
Sbjct: 330 PVPGSTRVEVEILSPVIHQPLAFALPDHTRFTLVDFPLHLPLELLGVDT-CLKVLTLILL 388

Query: 144 HERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGVPRS 203
            E ++ I +   + LS  V A    ++P+ +    IP+LP  +      P P  + VP S
Sbjct: 389 -EHKIIIQSRDYNALSMSVMALVHLIYPLEYMFPVIPLLPTCMGSAEHFPQP--LQVPGS 445

Query: 204 VMENVRMSEIG 214
              + R S  G
Sbjct: 446 ASNSQRSSFSG 456


>UniRef50_Q2UHD0 Cluster: Predicted protein; n=14;
           Pezizomycotina|Rep: Predicted protein - Aspergillus
           oryzae
          Length = 922

 Score = 35.9 bits (79), Expect = 1.8
 Identities = 18/86 (20%), Positives = 41/86 (47%), Gaps = 3/86 (3%)

Query: 140 AALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPIL-PKHLVDYMLAPMPFLI 198
           AA+   RR+  V+   + L+   +     +    W  +++P++  +H+ D +  P P+++
Sbjct: 298 AAVSPTRRIIFVSHYSAMLTIAAETIRYCVRVYEWSGLYVPVVHARHIKDLVQEPGPYIL 357

Query: 199 GVPRSVMENVRMSEIGDVVILDVDAN 224
           GV          +   D +++D+D N
Sbjct: 358 GVTAEC--RTLFNAPNDALVVDLDRN 381


>UniRef50_UPI00006A1CCB Cluster: DENN/MADD domain containing 4B.;
           n=3; Xenopus tropicalis|Rep: DENN/MADD domain containing
           4B. - Xenopus tropicalis
          Length = 1257

 Score = 35.5 bits (78), Expect = 2.4
 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 2/49 (4%)

Query: 178 FIPILPKHLVDYMLAPMPFLIGVPRSVMENVRMSEIGDVVILDVDANEL 226
           +IP+ P  L D + AP+PF++G+  S  +     +  DV+ +D+D N L
Sbjct: 194 YIPLCPLTLSDVLCAPVPFIVGIHSSYFDLHDPPQ--DVLCVDLDTNTL 240


>UniRef50_Q0FR11 Cluster: Chemotaxis multidomain, CheB
           methylesterase/CheR, Methylase; n=2;
           Rhodobacteraceae|Rep: Chemotaxis multidomain, CheB
           methylesterase/CheR, Methylase - Roseovarius sp.
           HTCC2601
          Length = 1154

 Score = 35.1 bits (77), Expect = 3.1
 Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 2/62 (3%)

Query: 204 VMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNALGDAVSRAFL 263
           ++ ++R+ E G   +L VDAN L S  + L+T+ P+   S+K A++   + GDA+   F 
Sbjct: 861 ILSSLRLDETG-CGVLGVDANAL-SLESLLDTVHPDDADSVKAAIAGLTSEGDAIDLTFK 918

Query: 264 RA 265
           RA
Sbjct: 919 RA 920


>UniRef50_A0CPR0 Cluster: Chromosome undetermined scaffold_23, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_23,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 628

 Score = 35.1 bits (77), Expect = 3.1
 Identities = 38/176 (21%), Positives = 83/176 (47%), Gaps = 20/176 (11%)

Query: 141 ALLHERRVAIVASKPSRLSACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPFLIGV 200
           A++ E +VAI+      ++  +   +  + P+++ H FI  +P+ L+  + AP+P  +G+
Sbjct: 471 AVILESKVAIINRSQKYIAYLMILLSFCIKPLNYFHPFILDVPEKLMPLLDAPVPVFLGL 530

Query: 201 PRSVMENVRMSEIGDVVILDVDAN-ELRSPFNDLETLPPELISSLKKALSDKNALGDAVS 259
               ME  R      V +  + +N E+ +       L  EL + +K  L + N +     
Sbjct: 531 Q---MEEFRQFNDDVVYVNTISSNVEIENVERLKSNLLIELENQIKPVLCNSNII----- 582

Query: 260 RAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQPFLRKILQSQIFQQF 315
              ++ +  L+  ++D +     Q +       +K+++    FL+KI ++QI+Q +
Sbjct: 583 --LIKKIEQLLNIFKDFM----NQALN-----RIKSKQAKDLFLQKIEETQIYQMY 627


>UniRef50_Q39RW8 Cluster: Sensor protein; n=2;
           Deltaproteobacteria|Rep: Sensor protein - Geobacter
           metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
          Length = 576

 Score = 34.7 bits (76), Expect = 4.1
 Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 2/84 (2%)

Query: 223 ANELRSPFNDLETLPPELISSLKKALSDKNALGDAVSRAFLRALVCLIGGYRDAIKIENG 282
           ++ELR+P N +      L+  L   ++D+ A    + R     L+ LI    D  KIE G
Sbjct: 359 SHELRTPLNSIIGFTGILLQGLGGPINDEQAKQLTMVRHSANHLLSLISDVLDISKIEAG 418

Query: 283 QLITFNPEAFVKTRKNMQPFLRKI 306
           QL   +PE F + R+++Q   + +
Sbjct: 419 QL-KISPEPF-QLRESVQKVTQSV 440


>UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=1;
           Rhodoferax ferrireducens T118|Rep: AMP-dependent
           synthetase and ligase - Rhodoferax ferrireducens (strain
           DSM 15236 / ATCC BAA-621 / T118)
          Length = 958

 Score = 34.7 bits (76), Expect = 4.1
 Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 9/113 (7%)

Query: 197 LIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKALSDKNALGD 256
           LIG+P  V    R+   G  +++   A+ + S       LPPE   + K+ L+D   +G 
Sbjct: 769 LIGLPLRVEGLARLPAAGPRIVVANHASYVDSMLLGA-VLPPEFSFAAKRELADAALIGP 827

Query: 257 AVSR---AFLRALVCLIGGYRDA----IKIENGQLITFNPEAFVKTRKNMQPF 302
           A+ R   AF+   V    G  D      ++  G+ + F PE  ++    +QPF
Sbjct: 828 ALRRLGIAFVER-VDAAQGIEDTKALQARVRAGESMVFFPEGRLRRASGLQPF 879


>UniRef50_Q23U73 Cluster: Putative uncharacterized protein; n=1;
           Tetrahymena thermophila SB210|Rep: Putative
           uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1266

 Score = 34.7 bits (76), Expect = 4.1
 Identities = 12/49 (24%), Positives = 28/49 (57%), Gaps = 1/49 (2%)

Query: 96  IYNAGHSVFTCQ-CPDSNKLPSIPDNCNLTEYFSAVDTKCMAGLWAALL 143
           I+++  ++++C  C  ++ +    +NC ++EYFS    +CM   W  ++
Sbjct: 290 IFDSKFNIYSCSNCSLASDVKDCQNNCQMSEYFSQFKNQCMKYCWNGII 338


>UniRef50_UPI00006CAA79 Cluster: hypothetical protein TTHERM_00670190;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00670190 - Tetrahymena thermophila SB210
          Length = 1792

 Score = 34.3 bits (75), Expect = 5.5
 Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 1/68 (1%)

Query: 138  LWAALLHERRVAIVASKPSRL-SACVQAANATLFPMSWQHIFIPILPKHLVDYMLAPMPF 196
            L+ +LL E  +  V    + L S  +  +N+ L P+ W +  I  LP+ L+  + +P+P 
Sbjct: 1575 LFLSLLLEHSLVFVTKNITLLTSTLLLFSNSILKPLKWINPMIFNLPQKLLPILDSPVPI 1634

Query: 197  LIGVPRSV 204
            L+G+ + +
Sbjct: 1635 LVGINKDI 1642


>UniRef50_Q23VY8 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1711

 Score = 34.3 bits (75), Expect = 5.5
 Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 23   DHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLE-----KLLNCIANIINSPERDQLH 76
            D L+E Y++FK+ E+Y+ EE I+  P       L+     +LL  I N IN   RD  +
Sbjct: 1456 DFLEEAYLIFKHKENYEYEENIQKQPYSLDNTQLQLQALLRLLRAIDNSINFLTRDSTY 1514


>UniRef50_A2EUI7 Cluster: Clan CA, family C19, ubiquitin
           hydrolase-like cysteine peptidase; n=1; Trichomonas
           vaginalis G3|Rep: Clan CA, family C19, ubiquitin
           hydrolase-like cysteine peptidase - Trichomonas
           vaginalis G3
          Length = 849

 Score = 34.3 bits (75), Expect = 5.5
 Identities = 15/53 (28%), Positives = 26/53 (49%)

Query: 14  ELFCEVSPGDHLKEPYVLFKYPESYKNEEEIKSIPKFTFPCSLEKLLNCIANI 66
           +LF      + +  P +  K  E Y+N + IK +   T  C +E +L C+ +I
Sbjct: 276 QLFSNPLNTERVSAPIIFSKSREFYENPQGIKGLVNLTNTCFIESILQCLVHI 328


>UniRef50_UPI0000D5576A Cluster: PREDICTED: similar to CG9451-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG9451-PA - Tribolium castaneum
          Length = 365

 Score = 33.9 bits (74), Expect = 7.2
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 338 NAYADKLNTGSGQKLKQQYRDWAKTVKKEGGAFF 371
           N+Y D LN+  GQKL +QY D+ + + +  G+ F
Sbjct: 159 NSYNDFLNSSDGQKLFRQYSDFGEYIMENSGSNF 192


>UniRef50_UPI00006CEB59 Cluster: hypothetical protein TTHERM_00370850;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00370850 - Tetrahymena thermophila SB210
          Length = 1252

 Score = 33.9 bits (74), Expect = 7.2
 Identities = 21/78 (26%), Positives = 42/78 (53%), Gaps = 4/78 (5%)

Query: 307  LQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSGQKLKQQYRDWAKTVKKE 366
            L+ + F +FI +   ++N+ R +N+ +EV    +   L++   +++ Q   D   T+  E
Sbjct: 965  LEKESFNEFIAK---IINTIRNYNNFYEVNMKLFIYNLDSPL-EEVAQTMDDQRITIATE 1020

Query: 367  GGAFFKTVKDKVLFNMFM 384
            G    +TVK+ VL + F+
Sbjct: 1021 GNILHQTVKESVLSSDFI 1038


>UniRef50_Q2GGB5 Cluster: Putative uncharacterized protein; n=6;
           Ehrlichia chaffeensis|Rep: Putative uncharacterized
           protein - Ehrlichia chaffeensis (strain Arkansas)
          Length = 551

 Score = 33.9 bits (74), Expect = 7.2
 Identities = 17/60 (28%), Positives = 33/60 (55%), Gaps = 3/60 (5%)

Query: 290 EAFVKTRKNMQPFLRKILQSQIFQQFIDERLDLLNSGRGFNDEFEVECNAYADKLNTGSG 349
           +++ K + N+ P +++  +  +F    ++ +  LN G G  D F++ECN  A  +N G G
Sbjct: 67  QSYTKIQSNL-PSIKEGKEVLVFVPLTEDTVSRLNFGGG--DIFKIECNTRASVMNLGQG 123


>UniRef50_A2Q963 Cluster: Contig An01c0240, complete genome; n=1;
            Aspergillus niger|Rep: Contig An01c0240, complete genome
            - Aspergillus niger
          Length = 1805

 Score = 33.9 bits (74), Expect = 7.2
 Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 3/56 (5%)

Query: 193  PMPFLIGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKAL 248
            P  FLIG+P++  + +  S++ D+V +D+D    R  ++D E LP     S +  L
Sbjct: 1728 PQAFLIGLPKNATKGLSPSDLSDLVAMDLDVQ--RGSYDD-EKLPESKSGSQRVGL 1780


>UniRef50_UPI0000584A98 Cluster: PREDICTED: hypothetical protein
           isoform 3; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein isoform 3 -
           Strongylocentrotus purpuratus
          Length = 174

 Score = 33.5 bits (73), Expect = 9.6
 Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 2/51 (3%)

Query: 198 IGVPRSVMENVRMSEIGDVVILDVDANELRSPFNDLETLPPELISSLKKAL 248
           +GVPR + EN+RMSE  + V  DV    LR     L   P +L   L KAL
Sbjct: 41  LGVPREMSENIRMSE--EEVFPDVTIALLRQWTRKLGFTPEQLAVELVKAL 89


>UniRef50_Q97DY8 Cluster: Predicted amidohydrolase; n=26;
           Clostridia|Rep: Predicted amidohydrolase - Clostridium
           acetobutylicum
          Length = 393

 Score = 33.5 bits (73), Expect = 9.6
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 11/84 (13%)

Query: 260 RAFLRALVCLIGGYRDAIKIENGQLITFNPEAFVKTRKNMQPFLR----KILQSQIF--Q 313
           + + RA+  ++     A+KI  G+    NP+A    +KNM P  R     +L+ ++F  Q
Sbjct: 134 KTYGRAIDKMVVLQPSAMKIAFGE----NPKANYD-KKNMMPSTRIAIAAMLREELFEAQ 188

Query: 314 QFIDERLDLLNSGRGFNDEFEVEC 337
           Q+ ++R +   SG  FN EF  EC
Sbjct: 189 QYYEKRKNAEKSGDSFNKEFRKEC 212


>UniRef50_Q9FX15 Cluster: F12G12.11 protein; n=1; Arabidopsis
           thaliana|Rep: F12G12.11 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 385

 Score = 33.5 bits (73), Expect = 9.6
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)

Query: 33  KYPESYKNEEEIKSIPKFTFPCSLEK---LLNCIA-NIINSPERDQLHSFLEACRIRPPM 88
           K+P S      I+ + K TF C L     L++ +A   IN P ++Q++S    C ++   
Sbjct: 45  KFPTSKIEFSSIEKLTKCTFLCGLVMCMLLVDALAFKSINDPIKNQINSCAAIC-VKQDD 103

Query: 89  PGHTLKVIYNA 99
           P H L+V+Y +
Sbjct: 104 PCHFLRVLYES 114


>UniRef50_Q9Y573 Cluster: Actin-binding protein IPP; n=29;
           Euteleostomi|Rep: Actin-binding protein IPP - Homo
           sapiens (Human)
          Length = 584

 Score = 33.5 bits (73), Expect = 9.6
 Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 6/124 (4%)

Query: 44  IKSIPKFTFPCSLEKLLNCIANIINSPERDQLHSFLEACRIRPPMPGHTLKVIYNAG--H 101
           I+ +  F    +L+ LL     +  SP+ ++  SFL+  ++RP       K +Y  G   
Sbjct: 240 IEGVSDFNLRVALQTLLKEYCEVCKSPKENKFCSFLQTSKVRPRKKAR--KYLYAVGGYT 297

Query: 102 SVFTCQCPDSNKLPSIPDNCNLTEYFSAVDT--KCMAGLWAALLHERRVAIVASKPSRLS 159
            +   +  DS  L  +      ++Y++ V +  +  +GL   +L     AI   K S + 
Sbjct: 298 RLQGGRWSDSRALSCVERFDTFSQYWTTVSSLHQARSGLGVTVLGGMVYAIGGEKDSMIF 357

Query: 160 ACVQ 163
            C +
Sbjct: 358 DCTE 361


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.322    0.138    0.416 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 443,308,641
Number of Sequences: 1657284
Number of extensions: 18784244
Number of successful extensions: 43798
Number of sequences better than 10.0: 187
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 43490
Number of HSP's gapped (non-prelim): 283
length of query: 386
length of database: 575,637,011
effective HSP length: 102
effective length of query: 284
effective length of database: 406,594,043
effective search space: 115472708212
effective search space used: 115472708212
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 73 (33.5 bits)

- SilkBase 1999-2023 -