Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000577-TA|BGIBMGA000577-PA|IPR000595|Cyclic
nucleotide-binding, IPR005821|Ion transport
(540 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 533 e-151
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 533 e-151
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 532 e-150
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 532 e-150
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 532 e-150
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 532 e-150
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 532 e-150
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 532 e-150
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 510 e-144
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 509 e-144
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 509 e-144
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 378 e-104
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 367 e-101
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 357 4e-98
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 321 3e-87
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 262 3e-69
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 262 3e-69
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 262 3e-69
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 262 3e-69
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 240 8e-63
AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor cGMP... 223 9e-58
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 158 5e-38
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 157 1e-37
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 155 4e-37
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 155 4e-37
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 155 4e-37
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 155 4e-37
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 151 8e-36
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 151 8e-36
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 140 1e-32
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 140 1e-32
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 140 1e-32
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 140 1e-32
AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein. 139 2e-32
AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member... 132 2e-30
AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subun... 129 2e-29
U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channe... 127 1e-28
DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated... 127 1e-28
DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium... 127 1e-28
BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated... 127 1e-28
AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b pr... 127 1e-28
AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related p... 127 1e-28
AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2... 127 1e-28
AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium... 127 1e-28
AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K... 127 1e-28
AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein. 127 1e-28
BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated... 122 2e-27
AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated... 122 2e-27
AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens ... 122 2e-27
AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium... 122 2e-27
AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein. 122 4e-27
AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein. 122 4e-27
AB022698-1|BAA83592.1| 1017|Homo sapiens BEC2 protein. 120 1e-26
AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like pota... 119 2e-26
AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated... 114 9e-25
AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens ... 114 9e-25
AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium... 114 9e-25
BT007336-1|AAP36000.1| 772|Homo sapiens potassium voltage-gated... 111 6e-24
BC001914-1|AAH01914.2| 773|Homo sapiens KCNH2 protein protein. 111 6e-24
AJ609614-1|CAE82156.1| 548|Homo sapiens potassium voltage-gated... 111 6e-24
AB044806-1|BAB19682.1| 888|Homo sapiens HERG-USO protein. 111 6e-24
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 105 4e-22
AF493798-1|AAM49574.1| 611|Homo sapiens potassium channel splic... 103 1e-21
AC005559-2|AAC33280.2| 528|Homo sapiens hyperpolarization activ... 89 4e-17
AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens ... 88 6e-17
BC035815-1|AAH35815.1| 732|Homo sapiens potassium voltage-gated... 81 1e-14
AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated... 63 2e-09
BC127673-1|AAI27674.1| 393|Homo sapiens KCNH2 protein protein. 60 1e-08
BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein. 60 2e-08
BC043409-1|AAH43409.1| 422|Homo sapiens KCNH5 protein protein. 43 0.003
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 40 0.017
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 40 0.022
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 40 0.022
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 39 0.051
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 39 0.051
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 39 0.051
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 39 0.051
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 39 0.051
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 39 0.051
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 39 0.051
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 39 0.051
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 36 0.27
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 36 0.27
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 36 0.27
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 36 0.27
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 36 0.48
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 36 0.48
AL929302-8|CAI41286.1| 659|Homo sapiens RALBP1 associated Eps d... 36 0.48
AL732371-2|CAI40017.1| 659|Homo sapiens RALBP1 associated Eps d... 36 0.48
AF512951-1|AAM43953.1| 520|Homo sapiens RALBP1 associated Eps d... 36 0.48
AF511533-1|AAM43933.1| 659|Homo sapiens RALBP1 associated Eps d... 36 0.48
AF010233-1|AAC02901.1| 521|Homo sapiens RalBP1-interacting prot... 36 0.48
AC009484-1|AAY15071.1| 157|Homo sapiens unknown protein. 36 0.48
AB208937-1|BAD92174.1| 514|Homo sapiens RalBP1 associated Eps d... 36 0.48
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 36 0.48
BC128576-1|AAI28577.1| 849|Homo sapiens KCNQ3 protein protein. 35 0.83
BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein. 35 0.83
AY061755-1|AAL33798.1| 3321|Homo sapiens nesprin-1 beta protein. 35 0.83
AF071491-1|AAC96101.1| 872|Homo sapiens potassium channel protein. 35 0.83
AF033347-1|AAB97314.1| 825|Homo sapiens potassium channel homol... 35 0.83
AB208890-1|BAD92127.1| 443|Homo sapiens potassium voltage-gated... 35 0.83
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 34 1.1
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 34 1.1
AK074484-1|BAC11016.1| 377|Homo sapiens for mitochondrial prod... 34 1.1
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 34 1.1
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 34 1.1
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 34 1.1
BC028704-1|AAH28704.2| 418|Homo sapiens arrestin domain contain... 34 1.5
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 33 1.9
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 33 1.9
BC110645-1|AAI10646.1| 788|Homo sapiens MDC1 protein protein. 33 1.9
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 33 1.9
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 33 1.9
BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance ... 33 1.9
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 33 1.9
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 33 1.9
AL845353-21|CAI41890.1| 1244|Homo sapiens mediator of DNA damage... 33 1.9
AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance ... 33 1.9
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 33 1.9
AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated p... 33 1.9
AB003476-1|BAA19927.1| 1684|Homo sapiens gravin protein. 33 1.9
BX248307-1|CAM25928.1| 305|Homo sapiens mediator of DNA damage ... 33 2.5
BC070100-1|AAH70100.1| 418|Homo sapiens arrestin domain contain... 33 2.5
AL662848-2|CAM24847.1| 305|Homo sapiens mediator of DNA damage ... 33 2.5
AL662797-6|CAM25512.1| 305|Homo sapiens mediator of DNA damage ... 33 2.5
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 33 3.4
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 33 3.4
BC067215-1|AAH67215.1| 1160|Homo sapiens EHBP1 protein protein. 33 3.4
AY531390-1|AAS48537.1| 1196|Homo sapiens EH domain binding prote... 33 3.4
AY331186-1|AAQ97141.1| 1231|Homo sapiens NPF/calponin-like prote... 33 3.4
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 33 3.4
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 33 3.4
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 33 3.4
AC009501-1|AAY24356.1| 125|Homo sapiens unknown protein. 33 3.4
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 33 3.4
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 33 3.4
AB020710-1|BAA74926.1| 962|Homo sapiens KIAA0903 protein protein. 33 3.4
U94780-1|AAB86593.1| 804|Homo sapiens MEA6 protein. 32 5.9
U73682-1|AAB86589.1| 776|Homo sapiens meningioma-expressed anti... 32 5.9
M96322-1|AAA35931.1| 306|Homo sapiens gravin protein. 32 5.9
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 32 5.9
BC039017-1|AAH39017.1| 309|Homo sapiens CTAGE5 protein protein. 32 5.9
BC029513-1|AAH29513.1| 395|Homo sapiens CTAGE5 protein protein. 32 5.9
BC012003-1|AAH12003.1| 365|Homo sapiens CEP135 protein protein. 32 5.9
AF338234-1|AAN77611.1| 771|Homo sapiens CTAGE-5B protein protein. 32 5.9
AF338233-1|AAN77610.1| 775|Homo sapiens CTAGE-5A protein protein. 32 5.9
AB209528-1|BAD92765.1| 808|Homo sapiens CTAGE family, member 5 ... 32 5.9
AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein. 32 5.9
U81607-1|AAC51366.1| 1781|Homo sapiens gravin protein. 31 7.8
BC005342-1|AAH05342.1| 282|Homo sapiens nucleosomal binding pro... 31 7.8
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 31 7.8
AL590413-4|CAI13591.1| 1684|Homo sapiens A kinase (PRKA) anchor ... 31 7.8
AL590413-3|CAI13590.1| 1782|Homo sapiens A kinase (PRKA) anchor ... 31 7.8
AL391294-5|CAI39710.1| 201|Homo sapiens nucleosomal binding pro... 31 7.8
AL391294-3|CAI39708.1| 282|Homo sapiens nucleosomal binding pro... 31 7.8
AL391294-2|CAI39707.1| 161|Homo sapiens nucleosomal binding pro... 31 7.8
AL356535-2|CAI16151.1| 1782|Homo sapiens A kinase (PRKA) anchor ... 31 7.8
AL033392-2|CAI20468.1| 1684|Homo sapiens A kinase (PRKA) anchor ... 31 7.8
AL033392-1|CAI20467.1| 1782|Homo sapiens A kinase (PRKA) anchor ... 31 7.8
AF250330-1|AAK14063.1| 282|Homo sapiens nucleosomal binding pro... 31 7.8
AF250329-1|AAK14062.1| 282|Homo sapiens nucleosomal binding pro... 31 7.8
AF001504-1|AAB58938.1| 1741|Homo sapiens myasthenia gravis autoa... 31 7.8
AB210003-1|BAE06085.1| 1791|Homo sapiens AKAP12 variant protein ... 31 7.8
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 31 7.8
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 31 7.8
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 533 bits (1316), Expect = e-151
Identities = 263/459 (57%), Positives = 328/459 (71%), Gaps = 12/459 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+VKD K LR +Y+ + +K D+ S+IPTD+ Y+ + D +H P VR NRLL
Sbjct: 204 LVKDTKKLRDNYIHTLQFKLDVASIIPTDLIYF-----AVD-IHSP---EVRFNRLLHFA 254
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
RM+E+FDRTET T+YPN FRI +V+ ILV+IHWNAC+Y+AIS +IGFG D WVY N+T
Sbjct: 255 RMFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITD 314
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
G L +YIY YWSTLTLTTIGETP P KD EYLFV+ DFL GVLIFATIVGN+GSM
Sbjct: 315 PEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSM 374
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN R EFQ K+D VK YM FRKVS +EA+VIRWF Y W +DE +L +LP
Sbjct: 375 ISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPA 434
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KL+AEIAI VHL TL++VRIF DCE G QVFSPGDYICRKGD+GKEMYI+
Sbjct: 435 KLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYII 494
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
K G+L VVADDG T A LSAGS FGE+S+L I G++ GNRRTAN+R+LGYSDLFCL+K
Sbjct: 495 KEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKD 554
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EA+ +YPDA+ L ERG ++L K+GLLDE E A + + ++E + +LET +E L
Sbjct: 555 DLMEAVTEYPDAKKVLEERGREILMKEGLLDEN--EVATSMEVDVQEKLGQLETNMETLY 612
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSD 458
R LLA+ Q ++KQR+ +E +M ++ D+ SD
Sbjct: 613 TRFGRLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSD 651
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 533 bits (1316), Expect = e-151
Identities = 263/459 (57%), Positives = 328/459 (71%), Gaps = 12/459 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+VKD K LR +Y+ + +K D+ S+IPTD+ Y+ + D +H P VR NRLL
Sbjct: 204 LVKDTKKLRDNYIHTLQFKLDVASIIPTDLIYF-----AVD-IHSP---EVRFNRLLHFA 254
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
RM+E+FDRTET T+YPN FRI +V+ ILV+IHWNAC+Y+AIS +IGFG D WVY N+T
Sbjct: 255 RMFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNACIYYAISKSIGFGVDTWVYPNITD 314
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
G L +YIY YWSTLTLTTIGETP P KD EYLFV+ DFL GVLIFATIVGN+GSM
Sbjct: 315 PEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYLFVIFDFLIGVLIFATIVGNVGSM 374
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN R EFQ K+D VK YM FRKVS +EA+VIRWF Y W +DE +L +LP
Sbjct: 375 ISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIRWFDYLWTNKKTVDEREILKNLPA 434
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KL+AEIAI VHL TL++VRIF DCE G QVFSPGDYICRKGD+GKEMYI+
Sbjct: 435 KLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYII 494
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
K G+L VVADDG T A LSAGS FGE+S+L I G++ GNRRTAN+R+LGYSDLFCL+K
Sbjct: 495 KEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKD 554
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EA+ +YPDA+ L ERG ++L K+GLLDE E A + + ++E + +LET +E L
Sbjct: 555 DLMEAVTEYPDAKKVLEERGREILMKEGLLDEN--EVATSMEVDVQEKLGQLETNMETLY 612
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSD 458
R LLA+ Q ++KQR+ +E +M ++ D+ SD
Sbjct: 613 TRFGRLLAEYTGAQQKLKQRITVLETKMKQNNEDDYLSD 651
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 232 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 282
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 283 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 342
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 343 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 402
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 403 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 462
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 463 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 522
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 523 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 582
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 583 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 641
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 642 TRFARLLAEYNATQMKMKQRLSQLE 666
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 214 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 264
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 265 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 324
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 325 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 384
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 385 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 444
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 445 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 504
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 505 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 564
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 565 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 623
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 624 TRFARLLAEYNATQMKMKQRLSQLE 648
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 232 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 282
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 283 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 342
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 343 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 402
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 403 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 462
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 463 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 522
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 523 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 582
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 583 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 641
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 642 TRFARLLAEYNATQMKMKQRLSQLE 666
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 236 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 286
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 287 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 346
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 347 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 406
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 407 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 466
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 467 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 526
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 527 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 586
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 587 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 645
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 646 TRFARLLAEYNATQMKMKQRLSQLE 670
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 232 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 282
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 283 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 342
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 343 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 402
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 403 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 462
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 463 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 522
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 523 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 582
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 583 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 641
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 642 TRFARLLAEYNATQMKMKQRLSQLE 666
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 532 bits (1313), Expect = e-150
Identities = 260/445 (58%), Positives = 325/445 (73%), Gaps = 11/445 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
MV D L HY ++ +K D+LSL+PTD+AY G+ + P VR NRLL+
Sbjct: 232 MVSDTNRLWQHYKTTTQFKLDVLSLVPTDLAYL--KVGT----NYP---EVRFNRLLKFS 282
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
R++E+FDRTET T+YPN FRI +V+ IL++IHWNAC+YFAIS IGFGTD+WVY N++
Sbjct: 283 RLFEFFDRTETRTNYPNMFRIGNLVLYILIIIHWNACIYFAISKFIGFGTDSWVYPNISI 342
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
+G L+ +YIYS YWSTLTLTTIGETP P KD EYLFVV DFL GVLIFATIVGN+GSM
Sbjct: 343 PEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYLFVVVDFLVGVLIFATIVGNVGSM 402
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIRWF Y WA +DE+ VL SLPD
Sbjct: 403 ISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIRWFDYLWANKKTVDEKEVLKSLPD 462
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KLKAEIAI VHLDTL++VRIFQDCE G VFSPGDYIC+KGD+GKEMYI+
Sbjct: 463 KLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYII 522
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G+L VVADDG T LS GS FGE+S+L I G+++GNRRTAN+R++GYSDLFCL+K
Sbjct: 523 NEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKD 582
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YP+A+ L E+G Q+L KD L+DE L A + +EE V +L ++++ L
Sbjct: 583 DLMEALTEYPEAKKALEEKGRQILMKDNLIDEEL-ARAGADPKDLEEKVEQLGSSLDTLQ 641
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIE 444
R LLA+ Q +MKQR++ +E
Sbjct: 642 TRFARLLAEYNATQMKMKQRLSQLE 666
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 510 bits (1257), Expect = e-144
Identities = 248/454 (54%), Positives = 324/454 (71%), Gaps = 12/454 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+VK+ L + Y + +K D+LSLIPTD+ Y+ + P I RLNRLLR
Sbjct: 229 LVKEELKLINKYKSNLQFKLDVLSLIPTDLLYF--------KLGWNYPEI-RLNRLLRFS 279
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
RM+E+F RTET T+YPN FRI +VM I+++IHWNAC++++IS AIGFG D WVY ++
Sbjct: 280 RMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDIND 339
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
G L +Y+YS YWSTLTLTTIGETP P +D+EY+FVV DFL GVLIFATIVGNIGSM
Sbjct: 340 PEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSM 399
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN AR EFQ ++D +KQYM FR VS ++E RVI+WF Y W +DE+ VL LPD
Sbjct: 400 ISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPD 459
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KL+AEIAI VHLDTL++VRIF DCE G QV+SPGDYIC+KGD+G+EMYI+
Sbjct: 460 KLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYII 519
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
K G+L VVADDG T LS GS FGE+S+L I G++ GNRRTAN++++GYSDLFCL+K
Sbjct: 520 KEGKLAVVADDGVTQFVVLSDGSTFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKD 579
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YPDA+ L E+G Q+L KDGLLD + +A + + +EE V ++E +V++L
Sbjct: 580 DLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNI-ANAGSDPKDLEEKVTRMEGSVDLLQ 638
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVD 453
R +LA+ Q ++KQR+ +E + L+ +D
Sbjct: 639 TRFARILAEYESMQQKLKQRLTKVE-KFLKPLID 671
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 509 bits (1256), Expect = e-144
Identities = 248/454 (54%), Positives = 324/454 (71%), Gaps = 12/454 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+VK+ L + Y + +K D+LSLIPTD+ Y+ + P I RLNRLLR
Sbjct: 225 LVKEELKLINKYKSNLQFKLDVLSLIPTDLLYF--------KLGWNYPEI-RLNRLLRFS 275
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
RM+E+F RTET T+YPN FRI +VM I+++IHWNAC++++IS AIGFG D WVY ++
Sbjct: 276 RMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDIND 335
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
G L +Y+YS YWSTLTLTTIGETP P +D+EY+FVV DFL GVLIFATIVGNIGSM
Sbjct: 336 PEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSM 395
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN AR EFQ ++D +KQYM FR VS ++E RVI+WF Y W +DE+ VL LPD
Sbjct: 396 ISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPD 455
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KL+AEIAI VHLDTL++VRIF DCE G QV+SPGDYIC+KGD+G+EMYI+
Sbjct: 456 KLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYII 515
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
K G+L VVADDG T LS GS FGE+S+L I G++ GNRRTAN++++GYSDLFCL+K
Sbjct: 516 KEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKD 575
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YPDA+ L E+G Q+L KDGLLD + +A + + +EE V ++E +V++L
Sbjct: 576 DLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNI-ANAGSDPKDLEEKVTRMEGSVDLLQ 634
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVD 453
R +LA+ Q ++KQR+ +E + L+ +D
Sbjct: 635 TRFARILAEYESMQQKLKQRLTKVE-KFLKPLID 667
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 509 bits (1256), Expect = e-144
Identities = 248/454 (54%), Positives = 324/454 (71%), Gaps = 12/454 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+VK+ L + Y + +K D+LSLIPTD+ Y+ + P I RLNRLLR
Sbjct: 229 LVKEELKLINKYKSNLQFKLDVLSLIPTDLLYF--------KLGWNYPEI-RLNRLLRFS 279
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVY-NLTG 119
RM+E+F RTET T+YPN FRI +VM I+++IHWNAC++++IS AIGFG D WVY ++
Sbjct: 280 RMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDIND 339
Query: 120 SRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
G L +Y+YS YWSTLTLTTIGETP P +D+EY+FVV DFL GVLIFATIVGNIGSM
Sbjct: 340 PEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSM 399
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
ISNMN AR EFQ ++D +KQYM FR VS ++E RVI+WF Y W +DE+ VL LPD
Sbjct: 400 ISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPD 459
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
KL+AEIAI VHLDTL++VRIF DCE G QV+SPGDYIC+KGD+G+EMYI+
Sbjct: 460 KLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYII 519
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
K G+L VVADDG T LS GS FGE+S+L I G++ GNRRTAN++++GYSDLFCL+K
Sbjct: 520 KEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKD 579
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLN 419
DL EAL +YPDA+ L E+G Q+L KDGLLD + +A + + +EE V ++E +V++L
Sbjct: 580 DLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNI-ANAGSDPKDLEEKVTRMEGSVDLLQ 638
Query: 420 NRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVD 453
R +LA+ Q ++KQR+ +E + L+ +D
Sbjct: 639 TRFARILAEYESMQQKLKQRLTKVE-KFLKPLID 671
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 378 bits (930), Expect = e-104
Identities = 176/261 (67%), Positives = 206/261 (78%), Gaps = 1/261 (0%)
Query: 98 LYFAISYAIGFGTDNWVY-NLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYL 156
+YFAIS IGFGTD+WVY N++ +G L+ +YIYS YWSTLTLTTIGETP P KD EYL
Sbjct: 1 IYFAISKFIGFGTDSWVYPNISIPEHGRLSRKYIYSLYWSTLTLTTIGETPPPVKDEEYL 60
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
FVV DFL GVLIFATIVGN+GSMISNMN +R EFQ K+D +KQYM FRKV+ +LE RVIR
Sbjct: 61 FVVVDFLVGVLIFATIVGNVGSMISNMNASRAEFQAKIDSIKQYMQFRKVTKDLETRVIR 120
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
WF Y WA +DE+ VL SLPDKLKAEIAI VHLDTL++VRIFQDCE G
Sbjct: 121 WFDYLWANKKTVDEKEVLKSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLR 180
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
VFSPGDYIC+KGD+GKEMYI+ G+L VVADDG T LS GS FGE+S+L I G++
Sbjct: 181 PTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSK 240
Query: 337 TGNRRTANVRALGYSDLFCLA 357
+GNRRTAN+R++GYSDLFCL+
Sbjct: 241 SGNRRTANIRSIGYSDLFCLS 261
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 367 bits (902), Expect = e-101
Identities = 172/261 (65%), Positives = 198/261 (75%), Gaps = 1/261 (0%)
Query: 98 LYFAISYAIGFGTDNWVY-NLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYL 156
+Y+AIS +IGFG D WVY N+T G L +YIY YWSTLTLTTIGETP P KD EYL
Sbjct: 1 IYYAISKSIGFGVDTWVYPNITDPEYGYLAREYIYCLYWSTLTLTTIGETPPPVKDEEYL 60
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
FV+ DFL GVLIFATIVGN+GSMISNMN R EFQ K+D VK YM FRKVS +EA+VIR
Sbjct: 61 FVIFDFLIGVLIFATIVGNVGSMISNMNATRAEFQAKIDAVKHYMQFRKVSKGMEAKVIR 120
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
WF Y W +DE +L +LP KL+AEIAI VHL TL++VRIF DCE G
Sbjct: 121 WFDYLWTNKKTVDEREILKNLPAKLRAEIAINVHLSTLKKVRIFHDCEAGLLVELVLKLR 180
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
QVFSPGDYICRKGD+GKEMYI+K G+L VVADDG T A LSAGS FGE+S+L I G++
Sbjct: 181 PQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVTQYALLSAGSCFGEISILNIKGSK 240
Query: 337 TGNRRTANVRALGYSDLFCLA 357
GNRRTAN+R+LGYSDLFCL+
Sbjct: 241 MGNRRTANIRSLGYSDLFCLS 261
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 357 bits (879), Expect = 4e-98
Identities = 163/261 (62%), Positives = 200/261 (76%), Gaps = 1/261 (0%)
Query: 98 LYFAISYAIGFGTDNWVY-NLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYL 156
++++IS AIGFG D WVY ++ G L +Y+YS YWSTLTLTTIGETP P +D+EY+
Sbjct: 1 VFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYV 60
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
FVV DFL GVLIFATIVGNIGSMISNMN AR EFQ ++D +KQYM FR VS ++E RVI+
Sbjct: 61 FVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIK 120
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
WF Y W +DE+ VL LPDKL+AEIAI VHLDTL++VRIF DCE G
Sbjct: 121 WFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQ 180
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
QV+SPGDYIC+KGD+G+EMYI+K G+L VVADDG T LS GS FGE+S+L I G++
Sbjct: 181 PQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSK 240
Query: 337 TGNRRTANVRALGYSDLFCLA 357
GNRRTAN++++GYSDLFCL+
Sbjct: 241 AGNRRTANIKSIGYSDLFCLS 261
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 321 bits (789), Expect = 3e-87
Identities = 160/335 (47%), Positives = 217/335 (64%), Gaps = 10/335 (2%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V D + Y+++ S+ DL SL+PTD+ Y P H P +RLNR LR P
Sbjct: 116 LVVDKGRISSRYVRTWSFFLDLASLMPTDVVYVRLGP------HTPT---LRLNRFLRAP 166
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
R++E FDRTET T+YPNAFRI K+++ I V+IHWN+CLYFA+S +GFG D WVY
Sbjct: 167 RLFEAFDRTETRTAYPNAFRIAKLMLYIFVVIHWNSCLYFALSRYLGFGRDAWVYPDPAQ 226
Query: 121 RNGS-LTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSM 179
L QY+YSFY+STL LTT+G+TP P ++ EYLF+V DFL V+ FATI+G++ S+
Sbjct: 227 PGFERLRRQYLYSFYFSTLILTTVGDTPPPAREEEYLFMVGDFLLAVMGFATIMGSMSSV 286
Query: 180 ISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPD 239
I NMN A F VK+YM + V+ +LE RVI W+ + +E +L LP+
Sbjct: 287 IYNMNTADAAFYPDHALVKKYMKLQHVNRKLERRVIDWYQHLQINKKMTNEVAILQHLPE 346
Query: 240 KLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIV 299
+L+AE+A+ VHL TL V+IFQ+CE Q +SPG+Y+CRKGD+G+EMYI+
Sbjct: 347 RLRAEVAVSVHLSTLSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYII 406
Query: 300 KRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAG 334
+ G+L VVADDG T A L AG FGE+S++ I G
Sbjct: 407 REGQLAVVADDGITQYAVLGAGLYFGEISIINIKG 441
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 262 bits (641), Expect = 3e-69
Identities = 136/387 (35%), Positives = 224/387 (57%), Gaps = 21/387 (5%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K +R++YLKS +K DLLSL+P D Y + + ++RL R L+
Sbjct: 721 IITDKKDMRNNYLKSRRFKMDLLSLLPLDFLY----------LKVGVNPLLRLPRCLKYM 770
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ R E+ S +R+ + +L +H N+CLY+ S G G+ +WVY+ G+
Sbjct: 771 AFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGN 830
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
YI +Y++ TL TIG P P+ E +F + ++ GV F+ ++G + ++
Sbjct: 831 -------SYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVV 883
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ +++ MD +YM F K+ ++ RV W+ YTW G LDE ++ LPDK
Sbjct: 884 GAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDK 943
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ ++AI V+ + + +V +FQ C+ V+ P DY+C+KG++G+EMYI++
Sbjct: 944 MRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQ 1003
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G++QV+ DGK+VL TL AGSVFGE+S+L + G GNRRTANV A G+++LF L K+
Sbjct: 1004 AGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGG---GNRRTANVVAHGFTNLFILDKK 1060
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKD 386
DL E L YP+++ L ++ ++LR +
Sbjct: 1061 DLNEILVHYPESQKLLRKKARRMLRSN 1087
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 262 bits (641), Expect = 3e-69
Identities = 136/387 (35%), Positives = 224/387 (57%), Gaps = 21/387 (5%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K +R++YLKS +K DLLSL+P D Y + + ++RL R L+
Sbjct: 93 IITDKKDMRNNYLKSRRFKMDLLSLLPLDFLY----------LKVGVNPLLRLPRCLKYM 142
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ R E+ S +R+ + +L +H N+CLY+ S G G+ +WVY+ G+
Sbjct: 143 AFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGN 202
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
YI +Y++ TL TIG P P+ E +F + ++ GV F+ ++G + ++
Sbjct: 203 -------SYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVV 255
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ +++ MD +YM F K+ ++ RV W+ YTW G LDE ++ LPDK
Sbjct: 256 GAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDK 315
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ ++AI V+ + + +V +FQ C+ V+ P DY+C+KG++G+EMYI++
Sbjct: 316 MRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQ 375
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G++QV+ DGK+VL TL AGSVFGE+S+L + G GNRRTANV A G+++LF L K+
Sbjct: 376 AGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGG---GNRRTANVVAHGFTNLFILDKK 432
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKD 386
DL E L YP+++ L ++ ++LR +
Sbjct: 433 DLNEILVHYPESQKLLRKKARRMLRSN 459
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 262 bits (641), Expect = 3e-69
Identities = 136/387 (35%), Positives = 224/387 (57%), Gaps = 21/387 (5%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K +R++YLKS +K DLLSL+P D Y + + ++RL R L+
Sbjct: 379 IITDKKDMRNNYLKSRRFKMDLLSLLPLDFLY----------LKVGVNPLLRLPRCLKYM 428
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ R E+ S +R+ + +L +H N+CLY+ S G G+ +WVY+ G+
Sbjct: 429 AFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGN 488
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
YI +Y++ TL TIG P P+ E +F + ++ GV F+ ++G + ++
Sbjct: 489 -------SYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVV 541
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ +++ MD +YM F K+ ++ RV W+ YTW G LDE ++ LPDK
Sbjct: 542 GAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDK 601
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ ++AI V+ + + +V +FQ C+ V+ P DY+C+KG++G+EMYI++
Sbjct: 602 MRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQ 661
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G++QV+ DGK+VL TL AGSVFGE+S+L + G GNRRTANV A G+++LF L K+
Sbjct: 662 AGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGG---GNRRTANVVAHGFTNLFILDKK 718
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKD 386
DL E L YP+++ L ++ ++LR +
Sbjct: 719 DLNEILVHYPESQKLLRKKARRMLRSN 745
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 262 bits (641), Expect = 3e-69
Identities = 136/387 (35%), Positives = 224/387 (57%), Gaps = 21/387 (5%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K +R++YLKS +K DLLSL+P D Y + + ++RL R L+
Sbjct: 715 IITDKKDMRNNYLKSRRFKMDLLSLLPLDFLY----------LKVGVNPLLRLPRCLKYM 764
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ R E+ S +R+ + +L +H N+CLY+ S G G+ +WVY+ G+
Sbjct: 765 AFFEFNSRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYQGLGSTHWVYDGVGN 824
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
YI +Y++ TL TIG P P+ E +F + ++ GV F+ ++G + ++
Sbjct: 825 -------SYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYFTGVFAFSVMIGQMRDVV 877
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ +++ MD +YM F K+ ++ RV W+ YTW G LDE ++ LPDK
Sbjct: 878 GAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDK 937
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ ++AI V+ + + +V +FQ C+ V+ P DY+C+KG++G+EMYI++
Sbjct: 938 MRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQ 997
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G++QV+ DGK+VL TL AGSVFGE+S+L + G GNRRTANV A G+++LF L K+
Sbjct: 998 AGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGG---GNRRTANVVAHGFTNLFILDKK 1054
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKD 386
DL E L YP+++ L ++ ++LR +
Sbjct: 1055 DLNEILVHYPESQKLLRKKARRMLRSN 1081
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 240 bits (588), Expect = 8e-63
Identities = 147/489 (30%), Positives = 243/489 (49%), Gaps = 23/489 (4%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D+ LR HY S+ ++ D+ S+IP DI Y ++ + R NR+L+
Sbjct: 283 IIVDSNELRKHYRTSTKFQLDVASIIPFDICYLFFGFNP----------MFRANRMLKYT 332
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ E+ +R+ + +L ++H NAC+Y+ S G GT WVY+ G+
Sbjct: 333 SFFEFNHHLESIMDKAYIYRVIRTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGN 392
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
+Y+ +YW+ TL TIG P+P+ E +F + +F +GV +F++++G + +I
Sbjct: 393 -------EYLRCYYWAVRTLITIGGLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVI 445
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ F+ MD YM + ++ RV W+ YTW LDE ++L +LP
Sbjct: 446 GAATANQNYFRACMDDTIAYMNNYSIPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTT 505
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ +AI V+ + +V +F+ C+ ++ PGD++C+KG++GKEMYI+K
Sbjct: 506 VQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIK 565
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G +QV+ DG VL TL AGSVFGE+S+L G GNRRTANV A G+++L L K+
Sbjct: 566 HGEVQVLGGPDGTKVLVTLKAGSVFGEISLLAAGG---GNRRTANVVAHGFANLLTLDKK 622
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEAL--FESAQTTQQSIEETVHKLETTVEM 417
L E L YPD+ L ++ LL++ EA + EET +T +
Sbjct: 623 TLQEILVHYPDSERILMKKARVLLKQKAKTAEATPPRKDLALLFPPKEETPKLFKTLLGG 682
Query: 418 LNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDL 477
L + EQA K+ + ++ D+ ++D + + K KD
Sbjct: 683 TGKASLARLLKLKREQAAQKKENSEGGEEEGKENEDKQKENEDKQKENEDKGKENEDKDK 742
Query: 478 ASGYSEAPM 486
E P+
Sbjct: 743 GREPEEKPL 751
>AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor
cGMP-gated cation channel beta-subunit protein.
Length = 610
Score = 223 bits (546), Expect = 9e-58
Identities = 144/489 (29%), Positives = 238/489 (48%), Gaps = 28/489 (5%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D+ LR HY S+ ++ D+ S+IP DI Y ++ + R NR+L+
Sbjct: 89 IIVDSNELRKHYRTSTKFQLDVASIIPFDICYLFFGFNP----------MFRANRMLKYT 138
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGS 120
+E+ E+ +R+ + +L ++H NAC+Y+ S G GT WVY+ G+
Sbjct: 139 SFFEFNHHLESIMDKAYIYRVIRTTGYLLFILHINACVYYWASNYEGIGTTRWVYDGEGN 198
Query: 121 RNGSLTHQYIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMI 180
+Y+ +YW+ TL TIG P+P+ E +F + +F +GV +F++++G + +I
Sbjct: 199 -------EYLRCYYWAVRTLITIGGLPEPQTLFEIVFQLLNFFSGVFVFSSLIGQMRDVI 251
Query: 181 SNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDK 240
+ F+ MD YM + ++ RV W+ YTW LDE ++L +LP
Sbjct: 252 GAATANQNYFRACMDDTIAYMNNYSIPKLVQKRVRTWYEYTWDSQRMLDESDLLKTLPTT 311
Query: 241 LKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVK 300
++ +AI V+ + +V +F+ C+ ++ PGD++C+KG++GKEMYI+K
Sbjct: 312 VQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIK 371
Query: 301 RGRLQVV-ADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKR 359
G +QV+ DG VL TL AG SVL AG GNRRTANV A G+++L L K+
Sbjct: 372 HGEVQVLGGPDGTKVLVTLKAG------SVLLAAGG--GNRRTANVVAHGFANLLTLDKK 423
Query: 360 DLWEALGDYPDARNTLTERGCQLLRKDGLLDEAL--FESAQTTQQSIEETVHKLETTVEM 417
L E L YPD+ L ++ LL++ EA + EET +T +
Sbjct: 424 TLQEILVHYPDSERILMKKARVLLKQKAKTAEATPPRKDLALLFPPKEETPKLFKTLLGG 483
Query: 418 LNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDL 477
L + EQA K+ + ++ D+ ++D + + K KD
Sbjct: 484 TGKASLARLLKLKREQAAQKKENSEGGEEEGKENEDKQKENEDKQKENEDKGKENEDKDK 543
Query: 478 ASGYSEAPM 486
E P+
Sbjct: 544 GREPEEKPL 552
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 158 bits (383), Expect = 5e-38
Identities = 117/412 (28%), Positives = 195/412 (47%), Gaps = 25/412 (6%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPV--------IVR 52
++ D K+++ +YLKS + D +S IP D + G ++ I+
Sbjct: 85 IILDPKVIKMNYLKSW-FVVDFISSIPVDYIFLIVEKGMDSEVYKTARALRIVRFTKILS 143
Query: 53 LNRLLRLPRMWEWFDRTETA--TSYPNA---FRICKVVMAILVLIHWNACLYFAISYAIG 107
L RLLRL R+ + + E +Y A RI ++ +L+L HW+ CL F +
Sbjct: 144 LLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQD 203
Query: 108 FGTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGV 166
F D WV +L N S QY Y+ + + + IG Q P ++ + + G
Sbjct: 204 FPPDCWV-SLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGA 262
Query: 167 LIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSG 226
+A VG+ ++I +++ +R ++Q K V+QYM+F K+ ++ ++ ++ + + Q
Sbjct: 263 TCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRY-QGK 321
Query: 227 ALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYI 286
DEEN+L+ L D L+ EI + + +F + +P +VF PGDYI
Sbjct: 322 IFDEENILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYI 381
Query: 287 CRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVR 346
R+G VGK+MY ++ G V+ K + L+ GS FGE+ +L T RRTA+VR
Sbjct: 382 IREGAVGKKMYFIQHGVAGVITKSSKEM--KLTDGSYFGEICLL------TKGRRTASVR 433
Query: 347 ALGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
A Y L+ L+ + E L +YP R L + G + L + Q
Sbjct: 434 ADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 485
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 157 bits (380), Expect = 1e-37
Identities = 117/412 (28%), Positives = 194/412 (47%), Gaps = 25/412 (6%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPV--------IVR 52
++ D K+++ +YLKS S D +S IP D + G ++ I+
Sbjct: 206 IILDPKVIKMNYLKSWS-VVDFISSIPVDYIFLIVEKGMDSEVYKTARALRIVRFTKILS 264
Query: 53 LNRLLRLPRMWEWFDRTETA--TSYPNA---FRICKVVMAILVLIHWNACLYFAISYAIG 107
L RLLRL R+ + + E +Y A RI ++ +L+L HW+ CL F +
Sbjct: 265 LLRLLRLSRLIRYIHQWEEIFHMTYDLASAVVRIFNLIGMMLLLCHWDGCLQFLVPLLQD 324
Query: 108 FGTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGV 166
F D WV +L N S QY Y+ + + + IG Q P ++ + + G
Sbjct: 325 FPPDCWV-SLNEMVNDSWGKQYSYALFKAMSHMLCIGYGAQAPVSMSDLWITMLSMIVGA 383
Query: 167 LIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSG 226
+A VG+ ++I +++ +R ++Q K V+QYM+F K+ ++ ++ ++ + + Q
Sbjct: 384 TCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQKIHDYYEHRY-QGK 442
Query: 227 ALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYI 286
DEEN+L+ L D L+ EI + + +F + +P +VF PGDYI
Sbjct: 443 IFDEENILNELNDPLRGEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYI 502
Query: 287 CRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVR 346
R+G VGK+MY ++ G V+ K + L+ GS FGE+ +L T RRTA+VR
Sbjct: 503 VREGAVGKKMYFIQHGVAGVITKSSKEM--KLTDGSYFGEICLL------TKGRRTASVR 554
Query: 347 ALGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
A Y L+ L+ + E +YP R L + G + L + Q
Sbjct: 555 ADTYCRLYSLSVDNFNEVPEEYPMMRRAFETVAIDRLDRIGKKNSILLQKFQ 606
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 155 bits (376), Expect = 4e-37
Identities = 99/351 (28%), Positives = 169/351 (48%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RIC ++ +L+L HW+ CL F + F
Sbjct: 337 LLRLSRLIRYIHQWEEIFHMTYDLASA--VMRICNLISMMLLLCHWDGCLQFLVPMLQDF 394
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
+ WV ++ G N S + Y ++ + + + IG Q PE + + + G
Sbjct: 395 PRNCWV-SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGAT 453
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + ++ ++ + + Q
Sbjct: 454 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY-QGKM 512
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DE+++L L L+ EI + + +F + +P +VF PGDYI
Sbjct: 513 FDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYII 572
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K + LS GS FGE+ +L T RRTA+VRA
Sbjct: 573 REGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLL------TRGRRTASVRA 624
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 625 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 675
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 155 bits (376), Expect = 4e-37
Identities = 99/351 (28%), Positives = 169/351 (48%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RIC ++ +L+L HW+ CL F + F
Sbjct: 337 LLRLSRLIRYIHQWEEIFHMTYDLASA--VMRICNLISMMLLLCHWDGCLQFLVPMLQDF 394
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
+ WV ++ G N S + Y ++ + + + IG Q PE + + + G
Sbjct: 395 PRNCWV-SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGAT 453
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + ++ ++ + + Q
Sbjct: 454 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY-QGKM 512
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DE+++L L L+ EI + + +F + +P +VF PGDYI
Sbjct: 513 FDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYII 572
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K + LS GS FGE+ +L T RRTA+VRA
Sbjct: 573 REGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLL------TRGRRTASVRA 624
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 625 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 675
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 155 bits (376), Expect = 4e-37
Identities = 99/351 (28%), Positives = 169/351 (48%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RIC ++ +L+L HW+ CL F + F
Sbjct: 337 LLRLSRLIRYIHQWEEIFHMTYDLASA--VMRICNLISMMLLLCHWDGCLQFLVPMLQDF 394
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
+ WV ++ G N S + Y ++ + + + IG Q PE + + + G
Sbjct: 395 PRNCWV-SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGAT 453
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + ++ ++ + + Q
Sbjct: 454 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY-QGKM 512
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DE+++L L L+ EI + + +F + +P +VF PGDYI
Sbjct: 513 FDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYII 572
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K + LS GS FGE+ +L T RRTA+VRA
Sbjct: 573 REGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLL------TRGRRTASVRA 624
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 625 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 675
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 155 bits (376), Expect = 4e-37
Identities = 99/351 (28%), Positives = 169/351 (48%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RIC ++ +L+L HW+ CL F + F
Sbjct: 191 LLRLSRLIRYIHQWEEIFHMTYDLASA--VMRICNLISMMLLLCHWDGCLQFLVPMLQDF 248
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
+ WV ++ G N S + Y ++ + + + IG Q PE + + + G
Sbjct: 249 PRNCWV-SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGAT 307
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + ++ ++ + + Q
Sbjct: 308 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY-QGKM 366
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DE+++L L L+ EI + + +F + +P +VF PGDYI
Sbjct: 367 FDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYII 426
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K + LS GS FGE+ +L T RRTA+VRA
Sbjct: 427 REGTIGKKMYFIQHGVVSVLTKGNKEM--KLSDGSYFGEICLL------TRGRRTASVRA 478
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 479 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQ 529
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 151 bits (365), Expect = 8e-36
Identities = 100/351 (28%), Positives = 167/351 (47%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 388 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIVNLIGMMLLLCHWDGCLQFLVPMLQDF 445
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY Y+ + + + IG Q P ++ + + G
Sbjct: 446 PDDCWV-SINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGAT 504
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 505 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRY-QGKM 563
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F + +P +VF PGDYI
Sbjct: 564 FDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYII 623
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K L+ GS FGE+ +L T RRTA+VRA
Sbjct: 624 REGTIGKKMYFIQHGVVSVLTKGNKE--TKLADGSYFGEICLL------TRGRRTASVRA 675
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 676 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQ 726
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 151 bits (365), Expect = 8e-36
Identities = 100/351 (28%), Positives = 167/351 (47%), Gaps = 14/351 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 388 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIVNLIGMMLLLCHWDGCLQFLVPMLQDF 445
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY Y+ + + + IG Q P ++ + + G
Sbjct: 446 PDDCWV-SINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGAT 504
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 505 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRY-QGKM 563
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F + +P +VF PGDYI
Sbjct: 564 FDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYII 623
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G +GK+MY ++ G + V+ K L+ GS FGE+ +L T RRTA+VRA
Sbjct: 624 REGTIGKKMYFIQHGVVSVLTKGNKE--TKLADGSYFGEICLL------TRGRRTASVRA 675
Query: 348 LGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQ 398
Y L+ L+ + E L +YP R L + G + L Q
Sbjct: 676 DTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQ 726
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 140 bits (338), Expect = 1e-32
Identities = 92/325 (28%), Positives = 157/325 (48%), Gaps = 14/325 (4%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 18 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIFNLIGMMLLLCHWDGCLQFLVPMLQDF 75
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY ++ + + + IG Q P + + + G
Sbjct: 76 PPDCWV-SINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGAT 134
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 135 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY-QGKM 193
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F +P +VF PGD +
Sbjct: 194 FDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVV 253
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G VG++MY ++ G L V+A + L+ GS FGE+ +L T RRTA+VRA
Sbjct: 254 REGSVGRKMYFIQHGLLSVLARGARD--TRLTDGSYFGEICLL------TRGRRTASVRA 305
Query: 348 LGYSDLFCLAKRDLWEALGDYPDAR 372
Y L+ L+ L ++P R
Sbjct: 306 DTYCRLYSLSVDHFNAVLEEFPMMR 330
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 140 bits (338), Expect = 1e-32
Identities = 92/325 (28%), Positives = 157/325 (48%), Gaps = 14/325 (4%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 221 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIFNLIGMMLLLCHWDGCLQFLVPMLQDF 278
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY ++ + + + IG Q P + + + G
Sbjct: 279 PPDCWV-SINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGAT 337
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 338 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY-QGKM 396
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F +P +VF PGD +
Sbjct: 397 FDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVV 456
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G VG++MY ++ G L V+A + L+ GS FGE+ +L T RRTA+VRA
Sbjct: 457 REGSVGRKMYFIQHGLLSVLARGARD--TRLTDGSYFGEICLL------TRGRRTASVRA 508
Query: 348 LGYSDLFCLAKRDLWEALGDYPDAR 372
Y L+ L+ L ++P R
Sbjct: 509 DTYCRLYSLSVDHFNAVLEEFPMMR 533
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 140 bits (338), Expect = 1e-32
Identities = 92/325 (28%), Positives = 157/325 (48%), Gaps = 14/325 (4%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 221 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIFNLIGMMLLLCHWDGCLQFLVPMLQDF 278
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY ++ + + + IG Q P + + + G
Sbjct: 279 PPDCWV-SINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGAT 337
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 338 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY-QGKM 396
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F +P +VF PGD +
Sbjct: 397 FDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVV 456
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G VG++MY ++ G L V+A + L+ GS FGE+ +L T RRTA+VRA
Sbjct: 457 REGSVGRKMYFIQHGLLSVLARGARD--TRLTDGSYFGEICLL------TRGRRTASVRA 508
Query: 348 LGYSDLFCLAKRDLWEALGDYPDAR 372
Y L+ L+ L ++P R
Sbjct: 509 DTYCRLYSLSVDHFNAVLEEFPMMR 533
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 140 bits (338), Expect = 1e-32
Identities = 92/325 (28%), Positives = 157/325 (48%), Gaps = 14/325 (4%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RI ++ +L+L HW+ CL F + F
Sbjct: 158 LLRLSRLIRYIHQWEEIFHMTYDLASA--VVRIFNLIGMMLLLCHWDGCLQFLVPMLQDF 215
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
D WV ++ N S QY ++ + + + IG Q P + + + G
Sbjct: 216 PPDCWV-SINHMVNHSWGRQYSHALFKAMSHMLCIGYGQQAPVGMPDVWLTMLSMIVGAT 274
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + + Q
Sbjct: 275 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY-QGKM 333
Query: 228 LDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYIC 287
DEE++L L + L+ EI + + +F +P +VF PGD +
Sbjct: 334 FDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVV 393
Query: 288 RKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRA 347
R+G VG++MY ++ G L V+A + L+ GS FGE+ +L T RRTA+VRA
Sbjct: 394 REGSVGRKMYFIQHGLLSVLARGARD--TRLTDGSYFGEICLL------TRGRRTASVRA 445
Query: 348 LGYSDLFCLAKRDLWEALGDYPDAR 372
Y L+ L+ L ++P R
Sbjct: 446 DTYCRLYSLSVDHFNAVLEEFPMMR 470
>AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein.
Length = 940
Score = 139 bits (337), Expect = 2e-32
Identities = 105/386 (27%), Positives = 186/386 (48%), Gaps = 32/386 (8%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V D + HY K + D+++ IP D+ + GS +++ RLLRL
Sbjct: 378 VVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLIF----GSGSDETTTLIGLLKTARLLRLV 432
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLI-HWNACLYFAI-SYAIGFGTDN--WV-- 114
R+ DR + Y A + ++M I LI HW AC+++AI + + TD W+
Sbjct: 433 RVARKLDRY---SEYGAA--VLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDS 487
Query: 115 --------YNLTGSRNG-SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLA 164
YN + S +G S+ +Y+ + Y++ +LT++G P ++E +F + L
Sbjct: 488 LGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLI 547
Query: 165 GVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQ 224
G L++A+I GN+ ++I + + +M VK+++ F ++ L R+ +F + W
Sbjct: 548 GSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTY 607
Query: 225 SGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGD 284
+ +D VL P+ L+A+I + ++ L+ + F+ G PGD
Sbjct: 608 TNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGD 667
Query: 285 YICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTAN 344
+ GDV +Y + RG ++++ DD V+A L +FGE+ L ++ A+
Sbjct: 668 TLVHCGDVLTALYFLSRGSIEILKDD--IVVAILGKNDIFGEMVHLYAKPGKS----NAD 721
Query: 345 VRALGYSDLFCLAKRDLWEALGDYPD 370
VRAL Y DL + + DL E L YP+
Sbjct: 722 VRALTYCDLHKIQREDLLEVLDMYPE 747
>AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member 2
protein.
Length = 994
Score = 132 bits (320), Expect = 2e-30
Identities = 103/385 (26%), Positives = 184/385 (47%), Gaps = 32/385 (8%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V + + HY K + D+++ IP D+ + GS + L +++ RLLRL
Sbjct: 330 VVSHPRRIAVHYFKGW-FLIDMVAAIPFDLLIF--RTGSDETTTLIG--LLKTARLLRLV 384
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLI-HWNACLYFAIS--------YAIGFGTD 111
R+ DR + Y A + ++M LI HW AC+++AI + IG+
Sbjct: 385 RVARKLDRY---SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDS 439
Query: 112 NWV-----YNLTGSRNG-SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLA 164
V YN + +G S+ +Y+ + Y++ +LT++G P ++E +F + L
Sbjct: 440 LGVQLGKRYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLI 499
Query: 165 GVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQ 224
G L++A+I GN+ ++I + + +M VK+++ F ++ L R+ +F + W+
Sbjct: 500 GSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWSY 559
Query: 225 SGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGD 284
+ +D VL P+ L+A+I + +H L+ F G PGD
Sbjct: 560 TNGIDMNAVLKGFPECLQADICLHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGD 619
Query: 285 YICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTAN 344
+ GDV +Y + RG ++++ DD V+A L +FGE ++ + + +A+
Sbjct: 620 TLVHLGDVLSTLYFISRGSIEILRDD--VVVAILGKNDIFGE----PVSLHAQPGKSSAD 673
Query: 345 VRALGYSDLFCLAKRDLWEALGDYP 369
VRAL Y DL + + DL E L YP
Sbjct: 674 VRALTYCDLHKIQRADLLEVLDMYP 698
>AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subunit
protein.
Length = 1196
Score = 129 bits (312), Expect = 2e-29
Identities = 102/386 (26%), Positives = 182/386 (47%), Gaps = 32/386 (8%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V D + HY K + D+++ IP D+ + GS +++ RLLRL
Sbjct: 481 VVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLIF----GSGSDETTTLIGLLKTARLLRLV 535
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVL-IHWNACLYFAI-SYAIGFGTDN--WV-- 114
R+ DR + Y A + + M I L HW AC+++AI + + TD W+
Sbjct: 536 RVARKLDRY---SEYGAA--VLMLSMCIFALNAHWLACIWYAIGNVERPYLTDKIGWLDS 590
Query: 115 --------YNLTGSRNG-SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLA 164
YN + S +G S+ +Y+ + Y++ +LT++G P ++E +F + L
Sbjct: 591 LGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLI 650
Query: 165 GVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQ 224
G L++A+I GN+ ++I + + +M VK+++ F ++ L R+ +F + W
Sbjct: 651 GSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTY 710
Query: 225 SGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGD 284
+ +D VL P+ L+A+I + ++ L+ + F+ G GD
Sbjct: 711 TNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHALQGD 770
Query: 285 YICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTAN 344
+ GDV +Y + RG +++ +D V+A L +FGE+ L ++ A+
Sbjct: 771 TLVHCGDVLTALYFLSRGSIEISKND--MVVAILGKNDIFGEMVHLYAKPGKS----NAD 824
Query: 345 VRALGYSDLFCLAKRDLWEALGDYPD 370
VRAL Y DL + + DL E L YP+
Sbjct: 825 VRALTYCDLHKIQREDLLEVLDMYPE 850
>U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channel
subunit protein.
Length = 1159
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 543 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 598
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 599 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 658
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 659 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 718
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 719 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 778
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 779 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 832
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 833 IHRDDLLEVLDMYPE 847
>DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated
channel subfamily H member 2 protein.
Length = 1159
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 543 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 598
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 599 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 658
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 659 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 718
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 719 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 778
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 779 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 832
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 833 IHRDDLLEVLDMYPE 847
>DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium
channel KV11.1 transcript variant 1 protein.
Length = 1159
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 543 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 598
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 599 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 658
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 659 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 718
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 719 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 778
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 779 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 832
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 833 IHRDDLLEVLDMYPE 847
>BC073979-1|AAH73979.1| 988|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 5 protein.
Length = 988
Score = 127 bits (306), Expect = 1e-28
Identities = 131/505 (25%), Positives = 218/505 (43%), Gaps = 46/505 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 277 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 335
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 336 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 388
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLF 157
+Y L G G S Y+ S Y++ +LTTIG P D E +F
Sbjct: 389 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMF 448
Query: 158 VVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRW 217
VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+ +
Sbjct: 449 SVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDY 508
Query: 218 FAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXX 277
TW+ S +D E VLS P ++A+I + ++ E F+ G
Sbjct: 509 IVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQT 568
Query: 278 QVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRT 337
+PGD I G+ + V G L+V+ DD V+A L G VFG++ E T
Sbjct: 569 IHCAPGDLIYHAGESVDALCFVVSGSLEVIQDD--EVVAILGKGDVFGDIFWKE----TT 622
Query: 338 GNRRTANVRALGYSDLFCLAKRDLWEALGDYPDARNTLTER---GCQLLRK--DGLLDEA 392
ANVRAL Y DL + + L + L Y N+ + C L ++ + +
Sbjct: 623 LAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDV 682
Query: 393 LFESAQTTQQSIEETVH-KLETTVEMLNNRL--QGLLADVGEEQAEMKQRMNNIEVRMLE 449
E + +Q E T+ ++ V L + Q L + G Q + ++ +E R L+
Sbjct: 683 KKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSTQGDPERNQLQVESRSLQ 742
Query: 450 DEVDELPSDDDVTSSDASELKSEIA 474
+ + VT S + +++ +A
Sbjct: 743 NGT-SITGTSVVTVSQITPIQTSLA 766
>AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b
protein protein.
Length = 819
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 152 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 202
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 203 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 258
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 259 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 318
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 319 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 378
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 379 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 438
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 439 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 492
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 493 IHRDDLLEVLDMYPE 507
>AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related
protein protein.
Length = 1133
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 466 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 516
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 517 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 572
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 573 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 632
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 633 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 692
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 693 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 752
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 753 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 806
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 807 IHRDDLLEVLDMYPE 821
>AF472412-1|AAM49565.1| 988|Homo sapiens potassium channel HEAG2
protein.
Length = 988
Score = 127 bits (306), Expect = 1e-28
Identities = 131/505 (25%), Positives = 218/505 (43%), Gaps = 46/505 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 277 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 335
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 336 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 388
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLF 157
+Y L G G S Y+ S Y++ +LTTIG P D E +F
Sbjct: 389 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMF 448
Query: 158 VVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRW 217
VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+ +
Sbjct: 449 SVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDY 508
Query: 218 FAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXX 277
TW+ S +D E VLS P ++A+I + ++ E F+ G
Sbjct: 509 IVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQT 568
Query: 278 QVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRT 337
+PGD I G+ + V G L+V+ DD V+A L G VFG++ E T
Sbjct: 569 IHCAPGDLIYHAGESVDALCFVVSGSLEVIQDD--EVVAILGKGDVFGDIFWKE----TT 622
Query: 338 GNRRTANVRALGYSDLFCLAKRDLWEALGDYPDARNTLTER---GCQLLRK--DGLLDEA 392
ANVRAL Y DL + + L + L Y N+ + C L ++ + +
Sbjct: 623 LAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDV 682
Query: 393 LFESAQTTQQSIEETVH-KLETTVEMLNNRL--QGLLADVGEEQAEMKQRMNNIEVRMLE 449
E + +Q E T+ ++ V L + Q L + G Q + ++ +E R L+
Sbjct: 683 KKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSTQGDPERNQLQVESRSLQ 742
Query: 450 DEVDELPSDDDVTSSDASELKSEIA 474
+ + VT S + +++ +A
Sbjct: 743 NGA-SITGTSVVTVSQITPIQTSLA 766
>AF418206-1|AAM28435.1| 988|Homo sapiens voltage-gated potassium
channel EAG2 protein.
Length = 988
Score = 127 bits (306), Expect = 1e-28
Identities = 131/505 (25%), Positives = 218/505 (43%), Gaps = 46/505 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 277 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 335
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 336 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 388
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLF 157
+Y L G G S Y+ S Y++ +LTTIG P D E +F
Sbjct: 389 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMF 448
Query: 158 VVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRW 217
VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+ +
Sbjct: 449 SVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDY 508
Query: 218 FAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXX 277
TW+ S +D E VLS P ++A+I + ++ E F+ G
Sbjct: 509 IVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQT 568
Query: 278 QVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRT 337
+PGD I G+ + V G L+V+ DD V+A L G VFG++ E T
Sbjct: 569 IHCAPGDLIYHAGESVDALCFVVSGSLEVIQDD--EVVAILGKGDVFGDIFWKE----TT 622
Query: 338 GNRRTANVRALGYSDLFCLAKRDLWEALGDYPDARNTLTER---GCQLLRK--DGLLDEA 392
ANVRAL Y DL + + L + L Y N+ + C L ++ + +
Sbjct: 623 LAHACANVRALTYCDLHIIKREALLKVLDFYTAFANSFSRNLTLTCNLRKRIIFRKISDV 682
Query: 393 LFESAQTTQQSIEETVH-KLETTVEMLNNRL--QGLLADVGEEQAEMKQRMNNIEVRMLE 449
E + +Q E T+ ++ V L + Q L + G Q + ++ +E R L+
Sbjct: 683 KKEEEERLRQKNEVTLSIPVDHPVRKLFQKFKQQKELRNQGSTQGDPERNQLQVESRSLQ 742
Query: 450 DEVDELPSDDDVTSSDASELKSEIA 474
+ + VT S + +++ +A
Sbjct: 743 NGT-SITGTSVVTVSQITPIQTSLA 766
>AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K+
channel protein protein.
Length = 1159
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 543 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 598
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 599 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 658
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 659 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 718
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 719 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 778
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 779 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 832
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 833 IHRDDLLEVLDMYPE 847
>AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein.
Length = 1159
Score = 127 bits (306), Expect = 1e-28
Identities = 99/375 (26%), Positives = 179/375 (47%), Gaps = 34/375 (9%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 543 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 598
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 599 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 658
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 659 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 718
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 719 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 778
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y DL
Sbjct: 779 LYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCDLHK 832
Query: 356 LAKRDLWEALGDYPD 370
+ + DL E L YP+
Sbjct: 833 IHRDDLLEVLDMYPE 847
>BC113709-1|AAI13710.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 122 bits (295), Expect = 2e-27
Identities = 108/392 (27%), Positives = 173/392 (44%), Gaps = 38/392 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P D+ + +VRL RL R+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVA 338
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTD-------NW 113
R + + A +C +A HW AC++++I F D +W
Sbjct: 339 RKLDHYIEYGAAVL---VLLVCVFGLAA----HWMACIWYSIGDYEIFDEDTKTIRNNSW 391
Query: 114 VYNLT----------GSRNG------SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYL 156
+Y L GS +G S YI S Y++ +LT++G P D E +
Sbjct: 392 LYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKI 451
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
F VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+
Sbjct: 452 FAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMD 511
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
+ TW+ S +D E VL P ++A+I + ++ +E F+ G
Sbjct: 512 YIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQ 571
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
+PGD I G+ + V G L+V+ DD V+A L G VFG+V E
Sbjct: 572 TVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDVFWKE----A 625
Query: 337 TGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
T + ANVRAL Y DL + + L + L Y
Sbjct: 626 TLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
>AL590132-2|CAH71752.1| 962|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 962
Score = 122 bits (295), Expect = 2e-27
Identities = 108/392 (27%), Positives = 173/392 (44%), Gaps = 38/392 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P D+ + +VRL RL R+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVA 338
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTD-------NW 113
R + + A +C +A HW AC++++I F D +W
Sbjct: 339 RKLDHYIEYGAAVL---VLLVCVFGLAA----HWMACIWYSIGDYEIFDEDTKTIRNNSW 391
Query: 114 VYNLT----------GSRNG------SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYL 156
+Y L GS +G S YI S Y++ +LT++G P D E +
Sbjct: 392 LYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKI 451
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
F VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+
Sbjct: 452 FAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMD 511
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
+ TW+ S +D E VL P ++A+I + ++ +E F+ G
Sbjct: 512 YIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQ 571
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
+PGD I G+ + V G L+V+ DD V+A L G VFG+V E
Sbjct: 572 TVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDVFWKE----A 625
Query: 337 TGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
T + ANVRAL Y DL + + L + L Y
Sbjct: 626 TLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
>AJ001366-1|CAA04700.1| 962|Homo sapiens protein ( Homo sapiens
potassium channel h-eag. ).
Length = 962
Score = 122 bits (295), Expect = 2e-27
Identities = 108/392 (27%), Positives = 173/392 (44%), Gaps = 38/392 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P D+ + +VRL RL R+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVA 338
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTD-------NW 113
R + + A +C +A HW AC++++I F D +W
Sbjct: 339 RKLDHYIEYGAAVL---VLLVCVFGLAA----HWMACIWYSIGDYEIFDEDTKTIRNNSW 391
Query: 114 VYNLT----------GSRNG------SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYL 156
+Y L GS +G S YI S Y++ +LT++G P D E +
Sbjct: 392 LYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKI 451
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
F VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+
Sbjct: 452 FAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMD 511
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
+ TW+ S +D E VL P ++A+I + ++ +E F+ G
Sbjct: 512 YIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQ 571
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
+PGD I G+ + V G L+V+ DD V+A L G VFG+V E
Sbjct: 572 TVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDVFWKE----A 625
Query: 337 TGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
T + ANVRAL Y DL + + L + L Y
Sbjct: 626 TLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
>AF078741-1|AAC68668.1| 962|Homo sapiens voltage-gated potassium
channel eag protein.
Length = 962
Score = 122 bits (295), Expect = 2e-27
Identities = 108/392 (27%), Positives = 173/392 (44%), Gaps = 38/392 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P D+ + +VRL RL R+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEGISSLFSSLKVVRLLRLGRVA 338
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTD-------NW 113
R + + A +C +A HW AC++++I F D +W
Sbjct: 339 RKLDHYIEYGAAVL---VLLVCVFGLAA----HWMACIWYSIGDYEIFDEDTKTIRNNSW 391
Query: 114 VYNLT----------GSRNG------SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYL 156
+Y L GS +G S YI S Y++ +LT++G P D E +
Sbjct: 392 LYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKI 451
Query: 157 FVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIR 216
F VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+
Sbjct: 452 FAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMD 511
Query: 217 WFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXX 276
+ TW+ S +D E VL P ++A+I + ++ +E F+ G
Sbjct: 512 YIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQ 571
Query: 277 XQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNR 336
+PGD I G+ + V G L+V+ DD V+A L G VFG+V E
Sbjct: 572 TVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVVAILGKGDVFGDVFWKE----A 625
Query: 337 TGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
T + ANVRAL Y DL + + L + L Y
Sbjct: 626 TLAQSCANVRALTYCDLHVIKRDALQKVLEFY 657
>AB033108-1|BAA86596.1| 1117|Homo sapiens KIAA1282 protein protein.
Length = 1117
Score = 122 bits (293), Expect = 4e-27
Identities = 71/248 (28%), Positives = 125/248 (50%), Gaps = 8/248 (3%)
Query: 124 SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMISN 182
SL YI S Y++ +LT++G D E +F + L G L+ A + GN+ ++I
Sbjct: 481 SLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQR 540
Query: 183 MNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLK 242
M R + ++ ++ Y+ ++ L+ R++ +F TWA + +D +L SLPD+L+
Sbjct: 541 MYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELR 600
Query: 243 AEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRG 302
A+IA+ +H + L ++ +F+ G +PG+Y+ +GD + +Y V G
Sbjct: 601 ADIAMHLHKEVL-QLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSG 659
Query: 303 RLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLW 362
++V+ G TVLA L G + G E+ + A+V+ L Y L CL L
Sbjct: 660 SMEVL--KGGTVLAILGKGDLIG----CELPRREQVVKANADVKGLTYCVLQCLQLAGLH 713
Query: 363 EALGDYPD 370
++L YP+
Sbjct: 714 DSLALYPE 721
>AB022696-1|BAA83590.1| 1083|Homo sapiens BEC1 protein.
Length = 1083
Score = 122 bits (293), Expect = 4e-27
Identities = 71/248 (28%), Positives = 125/248 (50%), Gaps = 8/248 (3%)
Query: 124 SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMISN 182
SL YI S Y++ +LT++G D E +F + L G L+ A + GN+ ++I
Sbjct: 447 SLRSAYITSLYFALSSLTSVGFGNVSANTDTEKIFSICTMLIGALMHAVVFGNVTAIIQR 506
Query: 183 MNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLK 242
M R + ++ ++ Y+ ++ L+ R++ +F TWA + +D +L SLPD+L+
Sbjct: 507 MYARRFLYHSRTRDLRDYIRIHRIPKPLKQRMLEYFQATWAVNNGIDTTELLQSLPDELR 566
Query: 243 AEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRG 302
A+IA+ +H + L ++ +F+ G +PG+Y+ +GD + +Y V G
Sbjct: 567 ADIAMHLHKEVL-QLPLFEAASRGCLRALSLALRPAFCTPGEYLIHQGDALQALYFVCSG 625
Query: 303 RLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLW 362
++V+ G TVLA L G + G E+ + A+V+ L Y L CL L
Sbjct: 626 SMEVL--KGGTVLAILGKGDLIG----CELPRREQVVKANADVKGLTYCVLQCLQLAGLH 679
Query: 363 EALGDYPD 370
++L YP+
Sbjct: 680 DSLALYPE 687
>AB022698-1|BAA83592.1| 1017|Homo sapiens BEC2 protein.
Length = 1017
Score = 120 bits (290), Expect = 1e-26
Identities = 104/388 (26%), Positives = 188/388 (48%), Gaps = 47/388 (12%)
Query: 11 HYLKSSSWKY-DLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRT 69
HYL ++W + DL++ +P D+ Y + + +HL ++ RLLRL R+ + +R
Sbjct: 303 HYL--ATWFFIDLIAALPFDLLYIFNITVT-SLVHL-----LKTVRLLRLLRLLQKLERY 354
Query: 70 ETATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTD------NWVYNLTGSR- 121
++ + ++M++ L+ HW AC+++ I D W++ L G R
Sbjct: 355 SQCSAV-----VLTLLMSVFALLAHWMACIWYVIGRREMEANDPLLWDIGWLHEL-GKRL 408
Query: 122 -----NGSL-----THQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFA 170
NGS+ YI + Y++ +LT++G DAE +F + L G L+ A
Sbjct: 409 EVPYVNGSVGGPSRRSAYIAALYFTLSSLTSVGFGNVCANTDAEKIFSICTMLIGALMHA 468
Query: 171 TIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDE 230
+ GN+ ++I M R + ++M +K ++ ++ L+ R++ +F TWA + +D
Sbjct: 469 VVFGNVTAIIQRMYSRRSLYHSRMKDLKDFIRVHRLPRPLKQRMLEYFQTTWAVNSGIDA 528
Query: 231 ENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKG 290
+L PD+L+A+IA+ ++ + L ++ +F G +PG+Y+ R+G
Sbjct: 529 NELLRDFPDELRADIAMHLNREIL-QLPLFGAASRGCLRALSLHIKTSFCAPGEYLLRRG 587
Query: 291 DVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTG--------NRRT 342
D + Y V G L+V+ D+ VLA L G + G + + G G + +
Sbjct: 588 DALQAHYYVCSGSLEVLRDN--MVLAILGKGDLIG--ADIPEPGQEPGLGADPNFVLKTS 643
Query: 343 ANVRALGYSDLFCLAKRDLWEALGDYPD 370
A+V+AL Y L L+ R L E L YP+
Sbjct: 644 ADVKALTYCGLQQLSSRGLAEVLRLYPE 671
>AY053503-1|AAL15429.1| 1107|Homo sapiens ether-a-go-go-like
potassium channel 1 protein.
Length = 1107
Score = 119 bits (287), Expect = 2e-26
Identities = 95/397 (23%), Positives = 188/397 (47%), Gaps = 40/397 (10%)
Query: 1 MVKDAKMLRHHYLKSSSWKY-DLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRL 59
++ +A+ + HY+ ++W DL++ +P D+ Y + +HL ++ RLLRL
Sbjct: 287 VIFEARSICIHYV--TTWFIIDLIAALPFDLLYAF-NVTVVSLVHL-----LKTVRLLRL 338
Query: 60 PRMWEWFDRTETATSYPNAFRICKVVMAILVLI-HWNACLYFAIS--------------- 103
R+ + DR ++ + ++M++ L+ HW AC+++ I
Sbjct: 339 LRLLQKLDRYSQHSTI-----VLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVG 393
Query: 104 --YAIGFGTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVA 160
+ +G ++ Y S+ YI + Y++ +LT++G DAE +F +
Sbjct: 394 WLHELGKRLESPYYGNNTLGGPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSIC 453
Query: 161 DFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAY 220
L G L+ A + GN+ ++I M + + +K ++ + +L+ R++ +F
Sbjct: 454 TMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQT 513
Query: 221 TWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVF 280
TW+ + +D +L PD+L+++I + ++ + L ++ +F+ G
Sbjct: 514 TWSVNNGIDSNELLKDFPDELRSDITMHLNKEIL-QLSLFECASRGCLRSLSLHIKTSFC 572
Query: 281 SPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNR 340
+PG+Y+ R+GD + +Y V G ++V+ D VLA L G + G + L I +
Sbjct: 573 APGEYLLRQGDALQAIYFVCSGSMEVLKD--SMVLAILGKGDLIG--ANLSIKDQVI--K 626
Query: 341 RTANVRALGYSDLFCLAKRDLWEALGDYPDARNTLTE 377
A+V+AL Y DL C+ + L+E L YP+ + E
Sbjct: 627 TNADVKALTYCDLQCIILKGLFEVLDLYPEYAHKFVE 663
>AL590132-1|CAH71753.1| 989|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 1 protein.
Length = 989
Score = 114 bits (274), Expect = 9e-25
Identities = 110/413 (26%), Positives = 181/413 (43%), Gaps = 53/413 (12%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDI----------AYYWWPPGSCDHM-HLPCPV 49
++ D K++R +YLK+ + DLLS +P D+ + + PG +P P+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPL 338
Query: 50 IVRLN----------RLLRLPRMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLY 99
R + +++RL R+ + + Y A + V + L HW AC++
Sbjct: 339 EGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAA-HWMACIW 397
Query: 100 FAISYAIGFGTD-------NWVYNLT----------GSRNG------SLTHQYIYSFYWS 136
++I F D +W+Y L GS +G S YI S Y++
Sbjct: 398 YSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFT 457
Query: 137 TLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMD 195
+LT++G P D E +F VA + G L++ATI GN+ ++ M + ++
Sbjct: 458 MTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLN 517
Query: 196 GVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLR 255
V+ ++ +V L RV+ + TW+ S +D E VL P ++A+I + ++ +
Sbjct: 518 SVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFK 577
Query: 256 EVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVL 315
E F+ G +PGD I G+ + V G L+V+ DD V+
Sbjct: 578 EHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVV 635
Query: 316 ATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
A L G VFG+V E T + ANVRAL Y DL + + L + L Y
Sbjct: 636 AILGKGDVFGDVFWKE----ATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 684
>AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens
cDNA FLJ34558 fis, clone KIDNE2001636, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 905
Score = 114 bits (274), Expect = 9e-25
Identities = 64/232 (27%), Positives = 114/232 (49%), Gaps = 7/232 (3%)
Query: 139 TLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGV 197
+LT++G P ++E +F + L G L++A+I GN+ ++I + + +M V
Sbjct: 420 SLTSVGFGNVSPNTNSEKVFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRV 479
Query: 198 KQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREV 257
K+++ F ++ L R+ +F + W+ + +D VL P+ L+A+I + +H L+
Sbjct: 480 KEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQHC 539
Query: 258 RIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLAT 317
F G PGD + GDV +Y + RG ++++ DD V+A
Sbjct: 540 PAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDD--VVVAI 597
Query: 318 LSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
L +FGE ++ + + +A+VRAL Y DL + + DL E L YP
Sbjct: 598 LGKNDIFGE----PVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYP 645
>AF078742-1|AAC68669.1| 989|Homo sapiens voltage-gated potassium
channel eagB protein.
Length = 989
Score = 114 bits (274), Expect = 9e-25
Identities = 110/413 (26%), Positives = 181/413 (43%), Gaps = 53/413 (12%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDI----------AYYWWPPGSCDHM-HLPCPV 49
++ D K++R +YLK+ + DLLS +P D+ + + PG +P P+
Sbjct: 280 VISDPKLIRMNYLKTW-FVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPL 338
Query: 50 IVRLN----------RLLRLPRMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLY 99
R + +++RL R+ + + Y A + V + L HW AC++
Sbjct: 339 EGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAA-HWMACIW 397
Query: 100 FAISYAIGFGTD-------NWVYNLT----------GSRNG------SLTHQYIYSFYWS 136
++I F D +W+Y L GS +G S YI S Y++
Sbjct: 398 YSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFT 457
Query: 137 TLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMD 195
+LT++G P D E +F VA + G L++ATI GN+ ++ M + ++
Sbjct: 458 MTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLN 517
Query: 196 GVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLR 255
V+ ++ +V L RV+ + TW+ S +D E VL P ++A+I + ++ +
Sbjct: 518 SVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFK 577
Query: 256 EVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVL 315
E F+ G +PGD I G+ + V G L+V+ DD V+
Sbjct: 578 EHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDD--EVV 635
Query: 316 ATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDY 368
A L G VFG+V E T + ANVRAL Y DL + + L + L Y
Sbjct: 636 AILGKGDVFGDVFWKE----ATLAQSCANVRALTYCDLHVIKRDALQKVLEFY 684
>BT007336-1|AAP36000.1| 772|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 2 protein.
Length = 772
Score = 111 bits (267), Expect = 6e-24
Identities = 89/361 (24%), Positives = 170/361 (47%), Gaps = 32/361 (8%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 376 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 426
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 427 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 482
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 483 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 542
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 543 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 602
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 603 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 662
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L G +G + LE+ + N+++LG C
Sbjct: 663 LYFISRGSIEILR--GDVVVAILGMG--WGAGTGLEMPSAASRGASLLNMQSLGLWTWDC 718
Query: 356 L 356
L
Sbjct: 719 L 719
>BC001914-1|AAH01914.2| 773|Homo sapiens KCNH2 protein protein.
Length = 773
Score = 111 bits (267), Expect = 6e-24
Identities = 89/361 (24%), Positives = 170/361 (47%), Gaps = 32/361 (8%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 377 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 427
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 428 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 483
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 484 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 543
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 544 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 603
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 604 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 663
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L G +G + LE+ + N+++LG C
Sbjct: 664 LYFISRGSIEILR--GDVVVAILGMG--WGAGTGLEMPSAASRGASLLNMQSLGLWTWDC 719
Query: 356 L 356
L
Sbjct: 720 L 720
>AJ609614-1|CAE82156.1| 548|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 2 protein.
Length = 548
Score = 111 bits (267), Expect = 6e-24
Identities = 89/361 (24%), Positives = 170/361 (47%), Gaps = 32/361 (8%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 152 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 202
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 203 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 258
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 259 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 318
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLS 235
+ ++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 319 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLK 378
Query: 236 SLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKE 295
P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 379 GFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTA 438
Query: 296 MYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFC 355
+Y + RG ++++ G V+A L G +G + LE+ + N+++LG C
Sbjct: 439 LYFISRGSIEILR--GDVVVAILGMG--WGAGTGLEMPSAASRGASLLNMQSLGLWTWDC 494
Query: 356 L 356
L
Sbjct: 495 L 495
>AB044806-1|BAB19682.1| 888|Homo sapiens HERG-USO protein.
Length = 888
Score = 111 bits (267), Expect = 6e-24
Identities = 86/360 (23%), Positives = 168/360 (46%), Gaps = 30/360 (8%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 492 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 542
Query: 71 TATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGFGTDN---WVYNL---------- 117
S A + ++ ++ HW AC+++AI D+ W++NL
Sbjct: 543 ---SXYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNS 599
Query: 118 TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGNI 176
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN+
Sbjct: 600 SGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNV 659
Query: 177 GSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSS 236
++I + + +M V++++ F ++ L R+ +F + W+ + +D VL
Sbjct: 660 SAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKG 719
Query: 237 LPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEM 296
P+ L+A+I + ++ L+ + F+ G PGD + GD+ +
Sbjct: 720 FPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTAL 779
Query: 297 YIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCL 356
Y + RG ++++ G V+A L G +G + LE+ + N+++LG CL
Sbjct: 780 YFISRGSIEILR--GDVVVAILGMG--WGAGTGLEMPSAASRGASLLNMQSLGLWTWDCL 835
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 105 bits (252), Expect = 4e-22
Identities = 61/210 (29%), Positives = 107/210 (50%), Gaps = 9/210 (4%)
Query: 163 LAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTW 222
+ G +A +G+ ++I +++ +R ++Q K V+QYM+F K+ + R+ ++ + +
Sbjct: 9 IVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADTRQRIHEYYEHRY 68
Query: 223 AQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSP 282
Q DEE++L L + L+ EI + + +F +P +VF P
Sbjct: 69 -QGKMFDEESILGELSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQP 127
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRT 342
GD + R+G VG++MY ++ G L V+A + L+ GS FGE+ +L T RRT
Sbjct: 128 GDLVVREGSVGRKMYFIQHGLLSVLARGARD--TRLTDGSYFGEICLL------TRGRRT 179
Query: 343 ANVRALGYSDLFCLAKRDLWEALGDYPDAR 372
A+VRA Y L+ L+ L ++P R
Sbjct: 180 ASVRADTYCRLYSLSVDHFNAVLEEFPMMR 209
>AF493798-1|AAM49574.1| 611|Homo sapiens potassium channel splice
variant HEAG2b protein.
Length = 611
Score = 103 bits (248), Expect = 1e-21
Identities = 90/333 (27%), Positives = 146/333 (43%), Gaps = 31/333 (9%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 277 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 335
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 336 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 388
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLF 157
+Y L G G S Y+ S Y++ +LTTIG P D E +F
Sbjct: 389 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMF 448
Query: 158 VVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRW 217
VA + G L++ATI GN+ ++ M + ++ V+ ++ +V L RV+ +
Sbjct: 449 SVAMMMVGSLLYATIFGNVTTIFQQMYANTNRYHEMLNNVRDFLKLYQVPKGLSERVMDY 508
Query: 218 FAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXX 277
TW+ S +D E VLS P ++A+I + ++ E F+ G
Sbjct: 509 IVSTWSMSKGIDTEKVLSICPKDMRADICVHLNRKVFNEHPAFRLASDGCLRALAVEFQT 568
Query: 278 QVFSPGDYICRKGDVGKEMYIVKRGRLQVVADD 310
+PGD I G+ + V G L+V+ DD
Sbjct: 569 IHCAPGDLIYHAGESVDALCFVVSGSLEVIQDD 601
>AC005559-2|AAC33280.2| 528|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 2
protein.
Length = 528
Score = 89.0 bits (211), Expect = 4e-17
Identities = 51/195 (26%), Positives = 98/195 (50%), Gaps = 6/195 (3%)
Query: 50 IVRLNRLLRLPRMWEW-FDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAISYAIGF 108
++RL+RL+R WE F T S RIC ++ +L+L HW+ CL F + F
Sbjct: 337 LLRLSRLIRYIHQWEEIFHMTYDLASA--VMRICNLISMMLLLCHWDGCLQFLVPMLQDF 394
Query: 109 GTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTLTTIGETPQ-PEKDAEYLFVVADFLAGVL 167
+ WV ++ G N S + Y ++ + + + IG Q PE + + + G
Sbjct: 395 PRNCWV-SINGMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGAT 453
Query: 168 IFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQSGA 227
+A +G+ ++I +++ +R ++Q K V+QYM+F K+ + ++ ++ + + Q
Sbjct: 454 CYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRY-QGKM 512
Query: 228 LDEENVLSSLPDKLK 242
DE+++L L L+
Sbjct: 513 FDEDSILGELNGPLR 527
>AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens
cDNA FLJ33650 fis, clone BRAMY2024514, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 430
Score = 88.2 bits (209), Expect = 6e-17
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 6/173 (3%)
Query: 197 VKQYMAFRKVSGELEARVIRWFAYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLRE 256
VK+++ F ++ L R+ +F + W+ + +D VL P+ L+A+I + +H L+
Sbjct: 4 VKEFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLHRALLQH 63
Query: 257 VRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLA 316
F G PGD + GDV +Y + RG ++++ DD V+A
Sbjct: 64 CPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEILRDD--VVVA 121
Query: 317 TLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
L +FGE ++ + + +A+VRAL Y DL + + DL E L YP
Sbjct: 122 ILGKNDIFGE----PVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYP 170
>BC035815-1|AAH35815.1| 732|Homo sapiens potassium voltage-gated
channel, subfamily H (eag-related), member 7 protein.
Length = 732
Score = 80.6 bits (190), Expect = 1e-14
Identities = 66/253 (26%), Positives = 123/253 (48%), Gaps = 26/253 (10%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V D + HY K + D+++ IP D+ + GS +++ RLLRL
Sbjct: 474 VVSDPAKIAIHYFKGW-FLIDMVAAIPFDLLIF----GSGSDETTTLIGLLKTARLLRLV 528
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLI-HWNACLYFAI-SYAIGFGTDN--WV-- 114
R+ DR + Y A + ++M I LI HW AC+++AI + + TD W+
Sbjct: 529 RVARKLDRY---SEYGAA--VLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDS 583
Query: 115 --------YNLTGSRNG-SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLA 164
YN + S +G S+ +Y+ + Y++ +LT++G P ++E +F + L
Sbjct: 584 LGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLI 643
Query: 165 GVLIFATIVGNIGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGELEARVIRWFAYTWAQ 224
G L++A+I GN+ ++I + + +M VK+++ F ++ L R+ +F + W
Sbjct: 644 GSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTY 703
Query: 225 SGALDEENVLSSL 237
+ +D V S+
Sbjct: 704 TNGIDMNMVCMSV 716
>AB209053-1|BAD92290.1| 583|Homo sapiens potassium voltage-gated
channel, subfamily H, member 8 variant protein.
Length = 583
Score = 63.3 bits (147), Expect = 2e-09
Identities = 40/145 (27%), Positives = 73/145 (50%), Gaps = 7/145 (4%)
Query: 233 VLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDV 292
+L PD+L+++I + ++ + L ++ +F+ G +PG+Y+ R+GD
Sbjct: 2 LLKDFPDELRSDITMHLNKEIL-QLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDA 60
Query: 293 GKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSD 352
+ +Y V G ++V+ D VLA L G + G ++ +T A+V+AL Y D
Sbjct: 61 LQAIYFVCSGSMEVLKDS--MVLAILGKGDLIGANLSIKDQVIKTN----ADVKALTYCD 114
Query: 353 LFCLAKRDLWEALGDYPDARNTLTE 377
L C+ + L+E L YP+ + E
Sbjct: 115 LQCIILKGLFEVLDLYPEYAHKFVE 139
>BC127673-1|AAI27674.1| 393|Homo sapiens KCNH2 protein protein.
Length = 393
Score = 60.5 bits (140), Expect = 1e-08
Identities = 55/215 (25%), Positives = 105/215 (48%), Gaps = 28/215 (13%)
Query: 11 HYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLPRMWEWFDRTE 70
HY K + D+++ IP D+ + GS + + L ++ RLLRL R+ DR
Sbjct: 152 HYFKGW-FLIDMVAAIPFDLLIFG--SGSEELIGL-----LKTARLLRLVRVARKLDRY- 202
Query: 71 TATSYPNAFRICKVVMAILVLI-HWNACLYFAISYAIGFGTDN---WVYNL--------- 117
+ Y A + ++M LI HW AC+++AI D+ W++NL
Sbjct: 203 --SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYN 258
Query: 118 -TGSRNGSLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLAGVLIFATIVGN 175
+G S+ +Y+ + Y++ +LT++G P ++E +F + L G L++A+I GN
Sbjct: 259 SSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGN 318
Query: 176 IGSMISNMNVARVEFQNKMDGVKQYMAFRKVSGEL 210
+ ++I + + +M V++++ F ++ L
Sbjct: 319 VSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPL 353
>BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein.
Length = 444
Score = 60.1 bits (139), Expect = 2e-08
Identities = 40/138 (28%), Positives = 64/138 (46%), Gaps = 6/138 (4%)
Query: 233 VLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDV 292
VL P+ L+A+I + ++ L+ + F+ G PGD + GD+
Sbjct: 1 VLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDL 60
Query: 293 GKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSD 352
+Y + RG ++++ G V+A L +FGE L R G + +VRAL Y D
Sbjct: 61 LTALYFISRGSIEILR--GDVVVAILGKNDIFGEPLNLYA---RPG-KSNGDVRALTYCD 114
Query: 353 LFCLAKRDLWEALGDYPD 370
L + + DL E L YP+
Sbjct: 115 LHKIHRDDLLEVLDMYPE 132
>BC043409-1|AAH43409.1| 422|Homo sapiens KCNH5 protein protein.
Length = 422
Score = 42.7 bits (96), Expect = 0.003
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 31/198 (15%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 219 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 277
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 278 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 330
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLF 157
+Y L G G S Y+ S Y++ +LTTIG P D E +F
Sbjct: 331 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMF 390
Query: 158 VVADFLAGVLIFATIVGN 175
VA + G F + N
Sbjct: 391 SVAMMMVGCKYFNFFIEN 408
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 40.3 bits (90), Expect = 0.017
Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 8/107 (7%)
Query: 242 KAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKR 301
K I ++ D L + + + +P + + G YI ++G+ G ++++
Sbjct: 151 KDSIEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAE 210
Query: 302 GRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRAL 348
GRL+V G+ +L+++ + FGE+++L N T RTA+V+A+
Sbjct: 211 GRLEVF--QGEKLLSSIPMWTTFGELAILY---NCT---RTASVKAI 249
Score = 39.9 bits (89), Expect = 0.022
Identities = 40/174 (22%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Query: 219 AYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQ 278
A T ++ ALD E V ++ + A+ + + LR V + ++ +
Sbjct: 248 AITNVKTWALDRE-VFQNIMRRT-AQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVE 305
Query: 279 VFSPGDYICRKGDVGKEMYIVKRGRLQVV----ADDGKTVLATLSAGSVFGEVSVLEIAG 334
+ GDYI R+G+ G +I+ +G+++V D ++ TL G FGE +++
Sbjct: 306 YYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALI---- 361
Query: 335 NRTGNRRTANVRALGYSDLFCLA--KRDLWEALGDYPDARNTLTERGCQLLRKD 386
+ + R+AN+ A +D+ CL + + +G + + + L L R D
Sbjct: 362 --SDDVRSANIIA-EENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDD 412
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 39.9 bits (89), Expect = 0.022
Identities = 40/174 (22%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Query: 219 AYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQ 278
A T ++ ALD E V ++ + A+ + + LR V + ++ +
Sbjct: 248 AITNVKTWALDRE-VFQNIMRRT-AQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVE 305
Query: 279 VFSPGDYICRKGDVGKEMYIVKRGRLQVV----ADDGKTVLATLSAGSVFGEVSVLEIAG 334
+ GDYI R+G+ G +I+ +G+++V D ++ TL G FGE +++
Sbjct: 306 YYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALI---- 361
Query: 335 NRTGNRRTANVRALGYSDLFCLA--KRDLWEALGDYPDARNTLTERGCQLLRKD 386
+ + R+AN+ A +D+ CL + + +G + + + L L R D
Sbjct: 362 --SDDVRSANIIA-EENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDD 412
Score = 39.5 bits (88), Expect = 0.029
Identities = 22/69 (31%), Positives = 43/69 (62%), Gaps = 8/69 (11%)
Query: 280 FSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGN 339
+ G YI ++G+ G ++++ GRL+V G+ +L+++ + FGE+++L N T
Sbjct: 189 YQQGSYIIKQGEPGNHIFVLAEGRLEVF--QGEKLLSSIPMWTTFGELAILY---NCT-- 241
Query: 340 RRTANVRAL 348
RTA+V+A+
Sbjct: 242 -RTASVKAI 249
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 39.9 bits (89), Expect = 0.022
Identities = 40/174 (22%), Positives = 78/174 (44%), Gaps = 15/174 (8%)
Query: 219 AYTWAQSGALDEENVLSSLPDKLKAEIAIRVHLDTLREVRIFQDCEPGXXXXXXXXXXXQ 278
A T ++ ALD E V ++ + A+ + + LR V + ++ +
Sbjct: 248 AITNVKTWALDRE-VFQNIMRRT-AQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVE 305
Query: 279 VFSPGDYICRKGDVGKEMYIVKRGRLQVV----ADDGKTVLATLSAGSVFGEVSVLEIAG 334
+ GDYI R+G+ G +I+ +G+++V D ++ TL G FGE +++
Sbjct: 306 YYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALI---- 361
Query: 335 NRTGNRRTANVRALGYSDLFCLA--KRDLWEALGDYPDARNTLTERGCQLLRKD 386
+ + R+AN+ A +D+ CL + + +G + + + L L R D
Sbjct: 362 --SDDVRSANIIA-EENDVACLVIDRETFNQTVGTFEELQKYLEGYVANLNRDD 412
Score = 39.5 bits (88), Expect = 0.029
Identities = 22/69 (31%), Positives = 43/69 (62%), Gaps = 8/69 (11%)
Query: 280 FSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIAGNRTGN 339
+ G YI ++G+ G ++++ GRL+V G+ +L+++ + FGE+++L N T
Sbjct: 189 YQQGSYIIKQGEPGNHIFVLAEGRLEVF--QGEKLLSSIPMWTTFGELAILY---NCT-- 241
Query: 340 RRTANVRAL 348
RTA+V+A+
Sbjct: 242 -RTASVKAI 249
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 130 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 172
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 212 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 271
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 272 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 304
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 130 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 172
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 212 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 271
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 272 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 304
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 34.7 bits (76), Expect = 0.83
Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGE 326
D + L TL G FGE
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE 307
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 118 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 160
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 292
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 118 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 160
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 292
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 45
Score = 34.7 bits (76), Expect = 0.83
Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 85 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 144
Query: 310 DGKT----VLATLSAGSVFGE 326
D + L TL G FGE
Sbjct: 145 DSPSEDPVFLRTLGKGDWFGE 165
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 118 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 160
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 292
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 45
Score = 34.7 bits (76), Expect = 0.83
Identities = 21/81 (25%), Positives = 34/81 (41%), Gaps = 4/81 (4%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 85 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 144
Query: 310 DGKT----VLATLSAGSVFGE 326
D + L TL G FGE
Sbjct: 145 DSPSEDPVFLRTLGKGDWFGE 165
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 145 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 187
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 319
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.7 bits (86), Expect = 0.051
Identities = 17/45 (37%), Positives = 31/45 (68%), Gaps = 2/45 (4%)
Query: 286 ICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVL 330
I ++GDVG +Y+++ G+++V + K L T+ G VFGE+++L
Sbjct: 118 IIKEGDVGSLVYVMEDGKVEVTKEGVK--LCTMGPGKVFGELAIL 160
Score = 35.5 bits (78), Expect = 0.48
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 250 HLDTLREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVAD 309
+++ L+ V FQ + G+YI R+G G +I+ +G + V +
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 310 DGKT----VLATLSAGSVFGEVSVLEIAGNRTGN 339
D + L TL G FGE L+ RT N
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGE-KALQGEDVRTAN 292
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 36.3 bits (80), Expect = 0.27
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVV--ADDG 311
L+ VR+ E Q GDY+ R G +Y+V+ G L++ DG
Sbjct: 142 LKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDG 201
Query: 312 K--TVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
K V + SV +S+L++ +RT + RA S + L YP
Sbjct: 202 KECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYP 261
Query: 370 DA 371
++
Sbjct: 262 ES 263
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 36.3 bits (80), Expect = 0.27
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVV--ADDG 311
L+ VR+ E Q GDY+ R G +Y+V+ G L++ DG
Sbjct: 142 LKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDG 201
Query: 312 K--TVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
K V + SV +S+L++ +RT + RA S + L YP
Sbjct: 202 KECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYP 261
Query: 370 DA 371
++
Sbjct: 262 ES 263
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 36.3 bits (80), Expect = 0.27
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVV--ADDG 311
L+ VR+ E Q GDY+ R G +Y+V+ G L++ DG
Sbjct: 148 LKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDG 207
Query: 312 K--TVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
K V + SV +S+L++ +RT + RA S + L YP
Sbjct: 208 KECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYP 267
Query: 370 DA 371
++
Sbjct: 268 ES 269
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 36.3 bits (80), Expect = 0.27
Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVV--ADDG 311
L+ VR+ E Q GDY+ R G +Y+V+ G L++ DG
Sbjct: 142 LKNVRVLGHFEKPLFLELCRHMVFQRLGQGDYVFRPGQPDASIYVVQDGLLELCLPGPDG 201
Query: 312 K--TVLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYP 369
K V + SV +S+L++ +RT + RA S + L YP
Sbjct: 202 KECVVKEVVPGDSVNSLLSILDVITGHQHPQRTVSARAARDSTVLRLPVEAFSAVFTKYP 261
Query: 370 DA 371
++
Sbjct: 262 ES 263
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 35.5 bits (78), Expect = 0.48
Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 15/123 (12%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKT 313
L+EV+ F+ P + G + R+GD+G Y V G L V + +
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 314 -----VLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRD---LWEAL 365
+ TL G+ FGE S+L+ R A + S+L + ++D LWE
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILD------NTPRHATIVTRESSELLRIEQKDFKALWEKY 150
Query: 366 GDY 368
Y
Sbjct: 151 RQY 153
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 35.5 bits (78), Expect = 0.48
Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 15/123 (12%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKT 313
L+EV+ F+ P + G + R+GD+G Y V G L V + +
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 314 -----VLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRD---LWEAL 365
+ TL G+ FGE S+L+ R A + S+L + ++D LWE
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILD------NTPRHATIVTRESSELLRIEQKDFKALWEKY 150
Query: 366 GDY 368
Y
Sbjct: 151 RQY 153
>AL929302-8|CAI41286.1| 659|Homo sapiens RALBP1 associated Eps
domain containing 2 protein.
Length = 659
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 398 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 454
>AL732371-2|CAI40017.1| 659|Homo sapiens RALBP1 associated Eps
domain containing 2 protein.
Length = 659
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 398 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 454
>AF512951-1|AAM43953.1| 520|Homo sapiens RALBP1 associated Eps
domain containing protein 2b protein.
Length = 520
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 259 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 315
>AF511533-1|AAM43933.1| 659|Homo sapiens RALBP1 associated Eps
domain containing protein 2a protein.
Length = 659
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 398 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 454
>AF010233-1|AAC02901.1| 521|Homo sapiens RalBP1-interacting protein
protein.
Length = 521
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 260 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 316
>AC009484-1|AAY15071.1| 157|Homo sapiens unknown protein.
Length = 157
Score = 35.5 bits (78), Expect = 0.48
Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 15/123 (12%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKT 313
L+EV+ F+ P + G + R+GD+G Y V G L V + +
Sbjct: 16 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 75
Query: 314 -----VLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRD---LWEAL 365
+ TL G+ FGE S+L+ R A + S+L + ++D LWE
Sbjct: 76 HQDAVTICTLGIGTAFGE-SILD------NTPRHATIVTRESSELLRIEQKDFKALWEKY 128
Query: 366 GDY 368
Y
Sbjct: 129 RQY 131
>AB208937-1|BAD92174.1| 514|Homo sapiens RalBP1 associated Eps
domain containing protein 2 variant protein.
Length = 514
Score = 35.5 bits (78), Expect = 0.48
Identities = 21/57 (36%), Positives = 29/57 (50%)
Query: 440 MNNIEVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVA 496
+N +E ++D D + DVTS D LKS I + L SE P T + +SL A
Sbjct: 306 LNRMEKTSVKDMADLPVPNQDVTSDDKQALKSTINEALPKDVSEDPATPKDSNSLKA 362
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 35.5 bits (78), Expect = 0.48
Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 15/123 (12%)
Query: 254 LREVRIFQDCEPGXXXXXXXXXXXQVFSPGDYICRKGDVGKEMYIVKRGRLQVVADDGKT 313
L+EV+ F+ P + G + R+GD+G Y V G L V + +
Sbjct: 38 LKEVKAFEKFHPNLLHQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSS 97
Query: 314 -----VLATLSAGSVFGEVSVLEIAGNRTGNRRTANVRALGYSDLFCLAKRD---LWEAL 365
+ TL G+ FGE S+L+ R A + S+L + ++D LWE
Sbjct: 98 HQDAVTICTLGIGTAFGE-SILD------NTPRHATIVTRESSELLRIEQKDFKALWEKY 150
Query: 366 GDY 368
Y
Sbjct: 151 RQY 153
>BC128576-1|AAI28577.1| 849|Homo sapiens KCNQ3 protein protein.
Length = 849
Score = 34.7 bits (76), Expect = 0.83
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 129 YIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADF-LAGVLIFATIVGNIGSMISNMNVAR 187
Y + +W +TL TIG + K E + A F L GV FA G +GS ++ +
Sbjct: 292 YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA----LK 347
Query: 188 VEFQNKMDGVKQYMAFRKVSGELEARVIRWFA 219
V+ Q++ K + RK + EL R++A
Sbjct: 348 VQEQHRQ---KHFEKRRKPAAELIQAAWRYYA 376
>BC006334-1|AAH06334.1| 502|Homo sapiens KCNH6 protein protein.
Length = 502
Score = 34.7 bits (76), Expect = 0.83
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 26/181 (14%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
+V + + HY K + D+++ IP D+ + GS + L +++ RLLRL
Sbjct: 330 VVSHPRRIAVHYFKGW-FLIDMVAAIPFDLLIF--RTGSDETTTLIG--LLKTARLLRLV 384
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLI-HWNACLYFAI--------SYAIGFGTD 111
R+ DR + Y A + ++M LI HW AC+++AI + IG+
Sbjct: 385 RVARKLDRY---SEYGAA--VLFLLMCTFALIAHWLACIWYAIGNVERPYLEHKIGWLDS 439
Query: 112 NWV-----YNLTGSRNG-SLTHQYIYSFYWSTLTLTTIG-ETPQPEKDAEYLFVVADFLA 164
V YN + +G S+ +Y+ + Y++ +LT++G P ++E +F + L
Sbjct: 440 LGVQLGKRYNGSDPASGPSVQDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLI 499
Query: 165 G 165
G
Sbjct: 500 G 500
>AY061755-1|AAL33798.1| 3321|Homo sapiens nesprin-1 beta protein.
Length = 3321
Score = 34.7 bits (76), Expect = 0.83
Identities = 21/86 (24%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 371 ARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLE-TTVEMLNNRLQGLLADV 429
A T+ LRK +L + L E ++ +E KL+ T ++ +A++
Sbjct: 74 AHGTIAWNSASQLRKQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAEL 133
Query: 430 GEEQAEMKQRMNNIEVRMLEDEVDEL 455
G E E++Q M I ++ L+D ++
Sbjct: 134 GRETEELRQ-MIKIRLQNLQDAAKDM 158
>AF071491-1|AAC96101.1| 872|Homo sapiens potassium channel protein.
Length = 872
Score = 34.7 bits (76), Expect = 0.83
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 129 YIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADF-LAGVLIFATIVGNIGSMISNMNVAR 187
Y + +W +TL TIG + K E + A F L GV FA G +GS ++ +
Sbjct: 303 YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA----LK 358
Query: 188 VEFQNKMDGVKQYMAFRKVSGELEARVIRWFA 219
V+ Q++ K + RK + EL R++A
Sbjct: 359 VQEQHRQ---KHFEKRRKPAAELIQAAWRYYA 387
>AF033347-1|AAB97314.1| 825|Homo sapiens potassium channel homolog
protein.
Length = 825
Score = 34.7 bits (76), Expect = 0.83
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 129 YIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADF-LAGVLIFATIVGNIGSMISNMNVAR 187
Y + +W +TL TIG + K E + A F L GV FA G +GS ++ +
Sbjct: 256 YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA----LK 311
Query: 188 VEFQNKMDGVKQYMAFRKVSGELEARVIRWFA 219
V+ Q++ K + RK + EL R++A
Sbjct: 312 VQEQHRQ---KHFEKRRKPAAELIQAAWRYYA 340
>AB208890-1|BAD92127.1| 443|Homo sapiens potassium voltage-gated
channel KQT-like protein 3 variant protein.
Length = 443
Score = 34.7 bits (76), Expect = 0.83
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 129 YIYSFYWSTLTLTTIGETPQPEKDAEYLFVVADF-LAGVLIFATIVGNIGSMISNMNVAR 187
Y + +W +TL TIG + K E + A F L GV FA G +GS ++ +
Sbjct: 229 YADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLA----LK 284
Query: 188 VEFQNKMDGVKQYMAFRKVSGELEARVIRWFA 219
V+ Q++ K + RK + EL R++A
Sbjct: 285 VQEQHRQ---KHFEKRRKPAAELIQAAWRYYA 313
>X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein.
Length = 1263
Score = 34.3 bits (75), Expect = 1.1
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADV 429
+ R +L E+ KD DE + E QT + + + K E E + LQ + +
Sbjct: 955 NVRLSLLEKKLDSAAKDA--DERI-EKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 1011
Query: 430 GEEQAEMKQRMNNIEVRMLE 449
E+AE+KQR+N+ R +E
Sbjct: 1012 EAEKAELKQRLNSQSKRTIE 1031
>BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein.
Length = 1139
Score = 34.3 bits (75), Expect = 1.1
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADV 429
+ R +L E+ KD DE + E QT + + + K E E + LQ + +
Sbjct: 836 NVRLSLLEKKLDSAAKDA--DERI-EKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 892
Query: 430 GEEQAEMKQRMNNIEVRMLE 449
E+AE+KQR+N+ R +E
Sbjct: 893 EAEKAELKQRLNSQSKRTIE 912
>AK074484-1|BAC11016.1| 377|Homo sapiens for mitochondrial
product. protein.
Length = 377
Score = 34.3 bits (75), Expect = 1.1
Identities = 46/166 (27%), Positives = 72/166 (43%), Gaps = 30/166 (18%)
Query: 1 MVKDAKMLRHHYLKSSSWKYDLLSLIPTDIAYYWWPPGSCDHMHLPCPVIVRLNRLLRLP 60
++ D K++R +YLK+ + DLLS +P DI + +VRL RL R+
Sbjct: 219 VISDPKLIRMNYLKTW-FVIDLLSCLPYDIINAFENVDEGISSLFSSLKVVRLLRLGRVA 277
Query: 61 RMWEWFDRTETATSYPNAFRICKVVMAILVLIHWNACLYFAI-SYAI------GFGTDNW 113
R + + Y A + V + LV HW AC++++I Y + D+W
Sbjct: 278 RKLDHY------LEYGAAVLVLLVCVFGLVA-HWLACIWYSIGDYEVIDEVTNTIQIDSW 330
Query: 114 VYNL-------------TGSRNG--SLTHQYIYSFYWSTLTLTTIG 144
+Y L G G S Y+ S Y++ +LTTIG
Sbjct: 331 LYQLALSIGTPYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIG 376
>AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein.
Length = 1261
Score = 34.3 bits (75), Expect = 1.1
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADV 429
+ R +L E+ KD DE + E QT + + + K E E + LQ + +
Sbjct: 953 NVRLSLLEKKLDSAAKDA--DERI-EKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 1009
Query: 430 GEEQAEMKQRMNNIEVRMLE 449
E+AE+KQR+N+ R +E
Sbjct: 1010 EAEKAELKQRLNSQSKRTIE 1029
>AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform
protein.
Length = 1144
Score = 34.3 bits (75), Expect = 1.1
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADV 429
+ R +L E+ KD DE + E QT + + + K E E + LQ + +
Sbjct: 836 NVRLSLLEKKLDSAAKDA--DERI-EKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 892
Query: 430 GEEQAEMKQRMNNIEVRMLE 449
E+AE+KQR+N+ R +E
Sbjct: 893 EAEKAELKQRLNSQSKRTIE 912
>AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform
protein.
Length = 1278
Score = 34.3 bits (75), Expect = 1.1
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADV 429
+ R +L E+ KD DE + E QT + + + K E E + LQ + +
Sbjct: 970 NVRLSLLEKKLDSAAKDA--DERI-EKVQTRLEETQALLRKKEKEFEETMDALQADIDQL 1026
Query: 430 GEEQAEMKQRMNNIEVRMLE 449
E+AE+KQR+N+ R +E
Sbjct: 1027 EAEKAELKQRLNSQSKRTIE 1046
>BC028704-1|AAH28704.2| 418|Homo sapiens arrestin domain containing
4 protein.
Length = 418
Score = 33.9 bits (74), Expect = 1.5
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
Query: 81 ICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTL 140
I +V ++ V IH + + GT YN GSRN S+ Q+ W TLTL
Sbjct: 286 IIRVDYSLAVYIHIPGAKKLMLELPLVIGTIP--YNGFGSRNSSIASQFSMDMSWLTLTL 343
Query: 141 TTIGETP 147
E P
Sbjct: 344 PEQSEAP 350
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>BC110645-1|AAI10646.1| 788|Homo sapiens MDC1 protein protein.
Length = 788
Score = 33.5 bits (73), Expect = 1.9
Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 4/134 (2%)
Query: 408 VHKLETTVEMLNNRLQGLLAD---VGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSS 464
V ++E + + L L+ D +GE ++ R E V +D
Sbjct: 353 VAQVEQDLPISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSED-NYG 411
Query: 465 DASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSMPLRERGHSFCVLRTTALLHAPPEP 524
D+ +L + + + S+ D A P +E G S C +TT LL+ P
Sbjct: 412 DSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGLLNCKMPP 471
Query: 525 RSKSLRIKRIQNES 538
K+ RI+ + S
Sbjct: 472 AEKASRIRAAEKVS 485
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>BC047324-1|AAH47324.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Query: 381 QLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRL-QGLLADVGEEQAEMKQR 439
++L++ E F Q + QS+E ++H +E+T E L L LL+ + E +
Sbjct: 740 KMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDA 799
Query: 440 MNNIEVRMLEDEVDEL 455
+N+ E+R L+ E +L
Sbjct: 800 LND-EIRQLQQENRQL 814
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>AL845353-21|CAI41890.1| 1244|Homo sapiens mediator of DNA damage
checkpoint 1 protein.
Length = 1244
Score = 33.5 bits (73), Expect = 1.9
Identities = 30/134 (22%), Positives = 51/134 (38%), Gaps = 4/134 (2%)
Query: 408 VHKLETTVEMLNNRLQGLLAD---VGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSS 464
V ++E + + L L+ D +GE ++ R E V +D
Sbjct: 285 VAQVEQDLPISRENLTDLVVDTDTLGESTQPQREGAQVPTGREREQHVGGTKDSED-NYG 343
Query: 465 DASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSMPLRERGHSFCVLRTTALLHAPPEP 524
D+ +L + + + S+ D A P +E G S C +TT LL+ P
Sbjct: 344 DSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGLLNCKMPP 403
Query: 525 RSKSLRIKRIQNES 538
K+ RI+ + S
Sbjct: 404 AEKASRIRAAEKVS 417
>AL359260-2|CAI16576.1| 1217|Homo sapiens structural maintenance of
chromosomes 3 protein.
Length = 1217
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Query: 381 QLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRL-QGLLADVGEEQAEMKQR 439
++L++ E F Q + QS+E ++H +E+T E L L LL+ + E +
Sbjct: 740 KMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDA 799
Query: 440 MNNIEVRMLEDEVDEL 455
+N+ E+R L+ E +L
Sbjct: 800 LND-EIRQLQQENRQL 814
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 33.5 bits (73), Expect = 1.9
Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 283 GDYICRKGDVGKEMYIVKRGRLQVVADDGKTVLATLSAGSVFGEVSVLEIA 333
G + +GD G YI+ +G + VV GK ++ TL G FG+++++ A
Sbjct: 228 GTVLFSQGDKGTSWYIIWKGSVNVVT-HGKGLVTTLHEGDDFGQLALVNDA 277
>AF020043-1|AAC14893.1| 1217|Homo sapiens chromosome-associated
polypeptide protein.
Length = 1217
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 2/76 (2%)
Query: 381 QLLRKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRL-QGLLADVGEEQAEMKQR 439
++L++ E F Q + QS+E ++H +E+T E L L LL+ + E +
Sbjct: 740 KMLKEKRQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAELGTDLLSQLSLEDQKRVDA 799
Query: 440 MNNIEVRMLEDEVDEL 455
+N+ E+R L+ E +L
Sbjct: 800 LND-EIRQLQQENRQL 814
>AB003476-1|BAA19927.1| 1684|Homo sapiens gravin protein.
Length = 1684
Score = 33.5 bits (73), Expect = 1.9
Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 4/103 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELP---S 457
Q ++++ V ET EML + LQ + + + Q L DE P +
Sbjct: 1457 QTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPLASAQDETPITSA 1516
Query: 458 DDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1517 KEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1558
>BX248307-1|CAM25928.1| 305|Homo sapiens mediator of DNA damage
checkpoint 1 protein.
Length = 305
Score = 33.1 bits (72), Expect = 2.5
Identities = 20/81 (24%), Positives = 33/81 (40%)
Query: 458 DDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSMPLRERGHSFCVLRTTAL 517
D + D+ +L + + + S+ D A P +E G S C +TT L
Sbjct: 7 DSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGL 66
Query: 518 LHAPPEPRSKSLRIKRIQNES 538
L+ P K+ RI+ + S
Sbjct: 67 LNCKMPPAEKASRIRAAEKVS 87
>BC070100-1|AAH70100.1| 418|Homo sapiens arrestin domain containing
4 protein.
Length = 418
Score = 33.1 bits (72), Expect = 2.5
Identities = 22/67 (32%), Positives = 29/67 (43%), Gaps = 2/67 (2%)
Query: 81 ICKVVMAILVLIHWNACLYFAISYAIGFGTDNWVYNLTGSRNGSLTHQYIYSFYWSTLTL 140
I +V ++ V IH + + GT YN GSRN S+ Q+ W TLTL
Sbjct: 286 IIRVDYSLAVYIHIPGAKKLMLELPLVIGTIP--YNGFGSRNSSIASQFSMDMSWLTLTL 343
Query: 141 TTIGETP 147
E P
Sbjct: 344 PEQPEAP 350
>AL662848-2|CAM24847.1| 305|Homo sapiens mediator of DNA damage
checkpoint 1 protein.
Length = 305
Score = 33.1 bits (72), Expect = 2.5
Identities = 20/81 (24%), Positives = 33/81 (40%)
Query: 458 DDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSMPLRERGHSFCVLRTTAL 517
D + D+ +L + + + S+ D A P +E G S C +TT L
Sbjct: 7 DSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGL 66
Query: 518 LHAPPEPRSKSLRIKRIQNES 538
L+ P K+ RI+ + S
Sbjct: 67 LNCKMPPAEKASRIRAAEKVS 87
>AL662797-6|CAM25512.1| 305|Homo sapiens mediator of DNA damage
checkpoint 1 protein.
Length = 305
Score = 33.1 bits (72), Expect = 2.5
Identities = 20/81 (24%), Positives = 33/81 (40%)
Query: 458 DDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSMPLRERGHSFCVLRTTAL 517
D + D+ +L + + + S+ D A P +E G S C +TT L
Sbjct: 7 DSEDNYGDSEDLDLQATQCFLENQGLEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGL 66
Query: 518 LHAPPEPRSKSLRIKRIQNES 538
L+ P K+ RI+ + S
Sbjct: 67 LNCKMPPAEKASRIRAAEKVS 87
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 9/75 (12%)
Query: 398 QTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPS 457
++ Q+S+++T++KLE E L+N +Q L D + E K R +NI++ + E+DE +
Sbjct: 422 KSLQESLQKTIYKLE---EQLHNEMQ--LKD----EMEQKCRTSNIKLDKIMKELDEEGN 472
Query: 458 DDDVTSSDASELKSE 472
S S+++ E
Sbjct: 473 QRRNLESTVSQIEKE 487
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 9/75 (12%)
Query: 398 QTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPS 457
++ Q+S+++T++KLE E L+N +Q L D + E K R +NI++ + E+DE +
Sbjct: 422 KSLQESLQKTIYKLE---EQLHNEMQ--LKD----EMEQKCRTSNIKLDKIMKELDEEGN 472
Query: 458 DDDVTSSDASELKSE 472
S S+++ E
Sbjct: 473 QRRNLESTVSQIEKE 487
>BC067215-1|AAH67215.1| 1160|Homo sapiens EHBP1 protein protein.
Length = 1160
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI---EVRMLEDEVDELPS 457
Q S+ E H LE E+LN L+ +LA ++ E ++R + E+ L ++ D L
Sbjct: 1064 QLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVR 1123
Query: 458 DDDVTSSDASELKSEIAKDL 477
D D A E + + L
Sbjct: 1124 DLDAQEKQAEEEDEHLERTL 1143
>AY531390-1|AAS48537.1| 1196|Homo sapiens EH domain binding protein 1
protein.
Length = 1196
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI---EVRMLEDEVDELPS 457
Q S+ E H LE E+LN L+ +LA ++ E ++R + E+ L ++ D L
Sbjct: 1100 QLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVR 1159
Query: 458 DDDVTSSDASELKSEIAKDL 477
D D A E + + L
Sbjct: 1160 DLDAQEKQAEEEDEHLERTL 1179
>AY331186-1|AAQ97141.1| 1231|Homo sapiens NPF/calponin-like protein
protein.
Length = 1231
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI---EVRMLEDEVDELPS 457
Q S+ E H LE E+LN L+ +LA ++ E ++R + E+ L ++ D L
Sbjct: 1135 QLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVR 1194
Query: 458 DDDVTSSDASELKSEIAKDL 477
D D A E + + L
Sbjct: 1195 DLDAQEKQAEEEDEHLERTL 1214
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 32.7 bits (71), Expect = 3.4
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 405 EETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSS 464
+E +H+L+ + L +LQGL VGE + QR E+ +L+ ++ E ++
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ--EIVVLQQQLQEAREQGELKEQ 1799
Query: 465 DASELKSEIAKDLA 478
E + LA
Sbjct: 1800 SLQSQLDEAQRALA 1813
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 32.7 bits (71), Expect = 3.4
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 405 EETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSS 464
+E +H+L+ + L +LQGL VGE + QR E+ +L+ ++ E ++
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ--EIVVLQQQLQEAREQGELKEQ 1799
Query: 465 DASELKSEIAKDLA 478
E + LA
Sbjct: 1800 SLQSQLDEAQRALA 1813
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 32.7 bits (71), Expect = 3.4
Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 405 EETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPSDDDVTSS 464
+E +H+L+ + L +LQGL VGE + QR E+ +L+ ++ E ++
Sbjct: 1742 QEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ--EIVVLQQQLQEAREQGELKEQ 1799
Query: 465 DASELKSEIAKDLA 478
E + LA
Sbjct: 1800 SLQSQLDEAQRALA 1813
>AC009501-1|AAY24356.1| 125|Homo sapiens unknown protein.
Length = 125
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI---EVRMLEDEVDELPS 457
Q S+ E H LE E+LN L+ +LA ++ E ++R + E+ L ++ D L
Sbjct: 29 QLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVR 88
Query: 458 DDDVTSSDASELKSEIAKDL 477
D D A E + + L
Sbjct: 89 DLDAQEKQAEEEDEHLERTL 108
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 9/75 (12%)
Query: 398 QTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEVDELPS 457
++ Q+S+++T++KLE E L+N +Q L D + E K R +NI++ + E+DE +
Sbjct: 100 KSLQESLQKTIYKLE---EQLHNEMQ--LKD----EMEQKCRTSNIKLDKIMKELDEEGN 150
Query: 458 DDDVTSSDASELKSE 472
S S+++ E
Sbjct: 151 QRRNLESTVSQIEKE 165
>AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein.
Length = 1068
Score = 32.7 bits (71), Expect = 3.4
Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 1/106 (0%)
Query: 388 LLDEALFESAQTTQQSIE-ETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVR 446
+L++A + + T++ ++ E+ H L+ + LQ L +E E ++RM +
Sbjct: 677 MLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQAL 736
Query: 447 MLEDEVDELPSDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDS 492
+LE EL S +L++ A+ A G +A DS
Sbjct: 737 LLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDS 782
>AB020710-1|BAA74926.1| 962|Homo sapiens KIAA0903 protein protein.
Length = 962
Score = 32.7 bits (71), Expect = 3.4
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI---EVRMLEDEVDELPS 457
Q S+ E H LE E+LN L+ +LA ++ E ++R + E+ L ++ D L
Sbjct: 866 QLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVR 925
Query: 458 DDDVTSSDASELKSEIAKDL 477
D D A E + + L
Sbjct: 926 DLDAQEKQAEEEDEHLERTL 945
>U94780-1|AAB86593.1| 804|Homo sapiens MEA6 protein.
Length = 804
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 112 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 171
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 172 RIQSLEDESKSLKS 185
>U73682-1|AAB86589.1| 776|Homo sapiens meningioma-expressed antigen
11 protein.
Length = 776
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 127 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 186
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 187 RIQSLEDESKSLKS 200
>M96322-1|AAA35931.1| 306|Homo sapiens gravin protein.
Length = 306
Score = 31.9 bits (69), Expect = 5.9
Identities = 23/103 (22%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG---LLADVGEEQAEMKQRMNNIEVRMLEDEVDELPS 457
Q ++++ V ET EML + LQ ++ ++ + ++ +DE +
Sbjct: 79 QTAVDQFVRTEETATEMLTSELQTQAHMIKADSQDAGQETEKEGEEPQASAQDETPITSA 138
Query: 458 DDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 139 KEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 180
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 31.9 bits (69), Expect = 5.9
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 17/89 (19%)
Query: 278 QVFSPGDYICRKGDVGKEMYIVKRGRLQV---------VADDGKTVLATLSAGSVFGEVS 328
+V++ G+ I +GD +IV+ G +++ V ++G +A S G FGE++
Sbjct: 295 KVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELA 354
Query: 329 VLEIAGNRTGNRRTANVRALGYSDLFCLA 357
++ T R A+ A+G + CLA
Sbjct: 355 LV------TNKPRAASAHAIG--TVKCLA 375
>BC039017-1|AAH39017.1| 309|Homo sapiens CTAGE5 protein protein.
Length = 309
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 112 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 171
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 172 RIQSLEDESKSLKS 185
>BC029513-1|AAH29513.1| 395|Homo sapiens CTAGE5 protein protein.
Length = 395
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 112 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 171
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 172 RIQSLEDESKSLKS 185
>BC012003-1|AAH12003.1| 365|Homo sapiens CEP135 protein protein.
Length = 365
Score = 31.9 bits (69), Expect = 5.9
Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 4/143 (2%)
Query: 335 NRTGNRRTANVRALGYSDLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALF 394
N+T + A++ D A +DL + + + + + T+T L K+ L + L
Sbjct: 56 NKTNEKLIAHLNI--QVDFLQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELT 113
Query: 395 ESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ-AEMKQRMNNIEVRMLEDEVD 453
E Q QQ LET + L + + + E Q E +E+ + + E +
Sbjct: 114 EIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKE 173
Query: 454 ELPSDDDVTSSDASELKSEIAKD 476
L SD+ + SD + ++ ++
Sbjct: 174 RL-SDELLVKSDLETVVHQLEQE 195
>AF338234-1|AAN77611.1| 771|Homo sapiens CTAGE-5B protein protein.
Length = 771
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 112 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 171
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 172 RIQSLEDESKSLKS 185
>AF338233-1|AAN77610.1| 775|Homo sapiens CTAGE-5A protein protein.
Length = 775
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 83 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 142
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 143 RIQSLEDESKSLKS 156
>AB209528-1|BAD92765.1| 808|Homo sapiens CTAGE family, member 5
isoform 1 variant protein.
Length = 808
Score = 31.9 bits (69), Expect = 5.9
Identities = 25/74 (33%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 389 LDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQ---AEMKQRMNNIEV 445
L +A FE T QS+E T KL + L + + L ++ EE+ +E + M +I
Sbjct: 116 LKDASFEKEATEAQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISK 175
Query: 446 RM--LEDEVDELPS 457
R+ LEDE L S
Sbjct: 176 RIQSLEDESKSLKS 189
>AB040942-1|BAA96033.1| 1326|Homo sapiens KIAA1509 protein protein.
Length = 1326
Score = 31.9 bits (69), Expect = 5.9
Identities = 24/107 (22%), Positives = 55/107 (51%), Gaps = 4/107 (3%)
Query: 370 DARNTLTERGCQLLRKDGLLDEAL---FESAQTTQQSIEETVHKLETTVEMLNNRLQGLL 426
+ N ER + LRK+ L +AL E + + QS+ +L+ ++E +++ Q L
Sbjct: 25 ERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLE 84
Query: 427 ADVGEEQAEMKQRMNNIE-VRMLEDEVDELPSDDDVTSSDASELKSE 472
+++GE +AE + ++E +R+ +++ D + ++L+ +
Sbjct: 85 SELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKD 131
>U81607-1|AAC51366.1| 1781|Homo sapiens gravin protein.
Length = 1781
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1554 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1612
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1613 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1655
>BC005342-1|AAH05342.1| 282|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 282
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 126
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 31.5 bits (68), Expect = 7.8
Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 6/75 (8%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNIEVRMLEDEV--DELPSD 458
+Q +EE H LE VE R Q L A E+ +M+Q + +E ++ E+E +L +
Sbjct: 774 KQELEEICHDLEARVEEEEERCQHLQA----EKKKMQQNIQELEEQLEEEESARQKLQLE 829
Query: 459 DDVTSSDASELKSEI 473
T + +L+ E+
Sbjct: 830 KVTTEAKLKKLEEEL 844
>AL590413-4|CAI13591.1| 1684|Homo sapiens A kinase (PRKA) anchor
protein (gravin) 12 protein.
Length = 1684
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1457 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1515
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1516 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1558
>AL590413-3|CAI13590.1| 1782|Homo sapiens A kinase (PRKA) anchor
protein (gravin) 12 protein.
Length = 1782
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1555 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1613
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1614 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1656
>AL391294-5|CAI39710.1| 201|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 201
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 47 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 106
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 107 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 143
>AL391294-3|CAI39708.1| 282|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 282
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 126
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
>AL391294-2|CAI39707.1| 161|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 161
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 57 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 116
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 117 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 153
>AL356535-2|CAI16151.1| 1782|Homo sapiens A kinase (PRKA) anchor
protein (gravin) 12 protein.
Length = 1782
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1555 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1613
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1614 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1656
>AL033392-2|CAI20468.1| 1684|Homo sapiens A kinase (PRKA) anchor
protein (gravin) 12 protein.
Length = 1684
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1457 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1515
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1516 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1558
>AL033392-1|CAI20467.1| 1782|Homo sapiens A kinase (PRKA) anchor
protein (gravin) 12 protein.
Length = 1782
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1555 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1613
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1614 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1656
>AF250330-1|AAK14063.1| 282|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 282
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 126
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
>AF250329-1|AAK14062.1| 282|Homo sapiens nucleosomal binding
protein 1 protein.
Length = 282
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/97 (20%), Positives = 41/97 (42%)
Query: 384 RKDGLLDEALFESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI 443
+++ +++E E+A+ + I E + VE+ ++ GE++ + + N
Sbjct: 67 KQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNE 126
Query: 444 EVRMLEDEVDELPSDDDVTSSDASELKSEIAKDLASG 480
E EDE D+ + D E E K+ +G
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
>AF001504-1|AAB58938.1| 1741|Homo sapiens myasthenia gravis
autoantigen gravin protein.
Length = 1741
Score = 31.5 bits (68), Expect = 7.8
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD ++ + ++ +DE
Sbjct: 1514 QTAVDQFVRTEETATEMLTSELQTQAHVIKAD-SQDAGQETEKEGEEPQASAQDETPITS 1572
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1573 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1615
>AB210003-1|BAE06085.1| 1791|Homo sapiens AKAP12 variant protein
protein.
Length = 1791
Score = 31.5 bits (68), Expect = 7.8
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 401 QQSIEETVHKLETTVEMLNNRLQG----LLADVGEEQAEMKQRMNNIEVRMLEDEVDELP 456
Q ++++ V ET EML + LQ + AD + E ++ + + +DE
Sbjct: 1564 QTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEDPQASA-QDETPITS 1622
Query: 457 SDDDVTSSDASELKSEIAKDLASGYSEAPMTSVNDSSLVASQSM 500
+ ++ S+ + S+I+KD++ SE MT + S V Q +
Sbjct: 1623 AKEESESTAVGQAHSDISKDMSEA-SEKTMTVEVEGSTVNDQQL 1665
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 31.5 bits (68), Expect = 7.8
Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 395 ESAQTTQQSIEETVHKLETTVEMLNNRLQGLLADVGEEQAEMKQRMNNI--EVRMLEDEV 452
+ Q + ++E ++++E E L NR L V E+ + +++ EV+ L E
Sbjct: 853 QELQEKTREVQERLNEMEQLKEQLENR-DSTLQTVEREKTLITEKLQQTLEEVKTLTQEK 911
Query: 453 DELPSDDDVTSSDASELKSEI 473
D+L + + +LKS+I
Sbjct: 912 DDLKQLQESLQIERDQLKSDI 932
>AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein.
Length = 864
Score = 31.5 bits (68), Expect = 7.8
Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Query: 352 DLFCLAKRDLWEALGDYPDARNTLTERGCQLLRKDGLLDEALFESAQTTQQSIEETVHKL 411
D A +DL + + + + + T+T L K+ L + L E Q QQ L
Sbjct: 2 DFLQQANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEELL 61
Query: 412 ETTVEMLNNRLQGLLADVGEEQ-AEMKQRMNNIEVRMLEDEVDELPSDDDVTSSDASELK 470
ET + L + + + E Q E +E+ + + E + L SD+ + SD +
Sbjct: 62 ETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERL-SDELLVKSDLETVV 120
Query: 471 SEIAKD 476
++ ++
Sbjct: 121 HQLEQE 126
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.400
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,557,966
Number of Sequences: 224733
Number of extensions: 3105300
Number of successful extensions: 12392
Number of sequences better than 10.0: 173
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 94
Number of HSP's that attempted gapping in prelim test: 12017
Number of HSP's gapped (non-prelim): 267
length of query: 540
length of database: 73,234,838
effective HSP length: 94
effective length of query: 446
effective length of database: 52,109,936
effective search space: 23241031456
effective search space used: 23241031456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 68 (31.5 bits)
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