Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000568-TA|BGIBMGA000568-PA|IPR006202|Neurotransmitter-
gated ion-channel ligand-binding, IPR006029|Neurotransmitter-gated
ion-channel transmembrane region, IPR006028|Gamma-aminobutyric acid A
receptor, IPR002289|Gamma-aminobutyric-acid A receptor, beta subunit,
IPR006201|Neurotransmitter-gated ion-channel
(374 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1... 373 e-102
UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 299 7e-80
UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 223 6e-57
UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49... 173 8e-42
UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 171 3e-41
UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 166 9e-40
UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subuni... 160 6e-38
UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 158 2e-37
UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 148 2e-34
UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 145 2e-33
UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 144 3e-33
UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 142 2e-32
UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subuni... 141 2e-32
UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve... 140 5e-32
UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;... 140 7e-32
UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella ve... 140 7e-32
UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 138 2e-31
UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea... 137 5e-31
UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella ve... 137 5e-31
UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 137 5e-31
UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 136 1e-30
UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 135 2e-30
UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromado... 134 3e-30
UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 131 2e-29
UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 131 2e-29
UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor... 130 8e-29
UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 129 1e-28
UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 128 3e-28
UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 125 2e-27
UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subuni... 124 3e-27
UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 124 4e-27
UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 124 4e-27
UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 124 5e-27
UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 122 2e-26
UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protei... 121 4e-26
UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated... 119 1e-25
UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 115 2e-24
UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 115 2e-24
UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella ve... 114 3e-24
UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 114 3e-24
UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 114 4e-24
UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 113 5e-24
UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop l... 113 9e-24
UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 113 9e-24
UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 112 1e-23
UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; ... 112 1e-23
UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 112 1e-23
UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 112 2e-23
UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subun... 112 2e-23
UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; R... 111 2e-23
UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella ve... 111 3e-23
UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 111 4e-23
UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;... 109 9e-23
UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 109 9e-23
UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 109 1e-22
UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 108 2e-22
UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protei... 107 5e-22
UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella ve... 106 8e-22
UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 106 1e-21
UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 105 1e-21
UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella ve... 105 2e-21
UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 105 2e-21
UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella ve... 105 2e-21
UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 pr... 105 2e-21
UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;... 104 4e-21
UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 103 6e-21
UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella ve... 103 8e-21
UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 103 8e-21
UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 103 1e-20
UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella ve... 103 1e-20
UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella ve... 101 2e-20
UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 101 3e-20
UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; ... 101 4e-20
UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 101 4e-20
UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 100 5e-20
UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; ... 100 7e-20
UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 100 7e-20
UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor... 99 9e-20
UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 99 9e-20
UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 99 2e-19
UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 98 3e-19
UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subun... 98 3e-19
UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 97 5e-19
UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 97 9e-19
UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop l... 95 2e-18
UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 95 2e-18
UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ... 95 3e-18
UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 95 3e-18
UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subuni... 95 3e-18
UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory... 95 4e-18
UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 94 6e-18
UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 93 8e-18
UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric ac... 93 1e-17
UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 92 2e-17
UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 92 2e-17
UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 91 4e-17
UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 91 6e-17
UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 90 1e-16
UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - ... 89 2e-16
UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopteryg... 89 2e-16
UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 88 4e-16
UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 87 5e-16
UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 87 7e-16
UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 87 7e-16
UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella ve... 86 1e-15
UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-amin... 85 2e-15
UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 82 2e-14
UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 82 2e-14
UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; ... 82 2e-14
UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.... 82 2e-14
UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor... 82 3e-14
UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome sh... 81 6e-14
UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 80 8e-14
UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 80 1e-13
UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 79 2e-13
UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whol... 74 7e-12
UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome sho... 71 7e-11
UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 70 1e-10
UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 68 3e-10
UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Re... 66 1e-09
UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; A... 66 1e-09
UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 61 5e-08
UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1... 60 7e-08
UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 57 9e-07
UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit p... 53 1e-05
UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; ... 52 3e-05
UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; ... 50 1e-04
UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 46 0.002
UniRef50_Q9WV58 Cluster: Gamma-aminobutyric acid A receptor gamm... 42 0.020
UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; ... 42 0.026
UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a pro... 40 0.11
UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 40 0.11
UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.24
UniRef50_A7I712 Cluster: Putative uncharacterized protein precur... 39 0.24
UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic ... 38 0.32
UniRef50_A0NGW8 Cluster: ENSANGP00000031454; n=1; Anopheles gamb... 38 0.32
UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 36 1.3
UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 36 1.3
UniRef50_Q5U3N0 Cluster: Pleckstrin homology domain-containing f... 36 1.3
UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 36 1.7
UniRef50_P02836 Cluster: Segmentation polarity homeobox protein ... 36 1.7
UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precurso... 36 1.7
UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 36 2.3
UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1; ... 36 2.3
UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 36 2.3
UniRef50_Q0V237 Cluster: Predicted protein; n=1; Phaeosphaeria n... 35 3.0
UniRef50_A5DNF5 Cluster: Putative uncharacterized protein; n=1; ... 35 3.0
UniRef50_UPI00006CC8B0 Cluster: hypothetical protein TTHERM_0029... 35 4.0
UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila ... 35 4.0
UniRef50_Q0CS36 Cluster: Putative uncharacterized protein; n=1; ... 35 4.0
UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2... 34 5.2
UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty... 34 5.2
UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 34 6.9
UniRef50_Q05QM7 Cluster: Putative uncharacterized protein; n=1; ... 34 6.9
UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 34 6.9
UniRef50_A7F7D1 Cluster: Predicted protein; n=1; Sclerotinia scl... 34 6.9
UniRef50_UPI0000F2D592 Cluster: PREDICTED: hypothetical protein;... 33 9.2
UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.2
UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep... 33 9.2
UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 33 9.2
UniRef50_Q6EEV4 Cluster: GRINL1A downstream protein Gdown4; n=1;... 33 9.2
UniRef50_Q0URS6 Cluster: Putative uncharacterized protein; n=1; ... 33 9.2
UniRef50_A4R7R7 Cluster: Putative uncharacterized protein; n=1; ... 33 9.2
UniRef50_Q8NFW5 Cluster: Diencephalon/mesencephalon homeobox pro... 33 9.2
>UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1b;
n=8; Pancrustacea|Rep: Ionotropic GABA receptor beta
subunit 1b - Homarus americanus (American lobster)
Length = 521
Score = 373 bits (917), Expect = e-102
Identities = 192/311 (61%), Positives = 223/311 (71%), Gaps = 20/311 (6%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
+I + + GY+M IR W+ G SV + S+VSLPQF+VLG+ ++ + S +TGNYSRL C
Sbjct: 225 IIEIESFGYSMDHIRLSWHAGDRSVVIESDVSLPQFRVLGYNRKTIISSTSTGNYSRLLC 284
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
EI FVRSMGYYLIQIYIPS LIV+ISWVSFWLNR+ATPARV+LG NA
Sbjct: 285 EIMFVRSMGYYLIQIYIPSSLIVVISWVSFWLNRSATPARVSLGVTTVLTMTTLMSSTNA 344
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
ALPKISYVKSIDVYLGTCFVMVFASLLEYA VGYM KRIQMRK R +AIQK+A ++K
Sbjct: 345 ALPKISYVKSIDVYLGTCFVMVFASLLEYAAVGYMGKRIQMRKNRILAIQKMAEQRKTA- 403
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
TL + P P +T EVR+K+HDPKAHSKGGTLENTIN G AD
Sbjct: 404 --------TLDHSHASQDHPDHAPKQT---EVRYKLHDPKAHSKGGTLENTIN---GRAD 449
Query: 308 EENPGP-HPIHPGKDI----SKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDV 362
EE P P + P KDI +KL G +PSDIDKYSRIVFPVCFVCFNLMYWIIYLH+SD
Sbjct: 450 EEAPPPIANLLPHKDINKGLNKLYGCSPSDIDKYSRIVFPVCFVCFNLMYWIIYLHISDD 509
Query: 363 VANDLVLLEED 373
DL+L ++
Sbjct: 510 STEDLILHNQE 520
Score = 47.2 bits (107), Expect = 7e-04
Identities = 23/47 (48%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVG 75
GY+M IR W G SV + ++V LPQFRVLG+ R T+I+ T+ G
Sbjct: 232 GYSMDHIRLSWHAGDRSVVIESDVSLPQFRVLGY-NRKTIISSTSTG 277
Score = 40.7 bits (91), Expect = 0.060
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
Query: 4 DVNISAILDSFSISYDKRVRPNYGVGYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHR 63
D NISAILDS YDKR+RP YG + I + S+ +EVQ+ +
Sbjct: 45 DGNISAILDSLQTGYDKRIRPQYGESHVDVGITMY----ILSISSLSEVQMGKGSFTAAT 100
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSL 100
+T G + EGP S G S + +L
Sbjct: 101 NSGRAAAMTPAGGS------NAGEGPESDGPSQDFTL 131
>UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=45;
Pancrustacea|Rep: Gamma-aminobutyric acid receptor
subunit beta precursor (GABA(A) receptor subunit beta) -
Drosophila melanogaster (Fruit fly)
Length = 606
Score = 299 bits (734), Expect = 7e-80
Identities = 144/176 (81%), Positives = 153/176 (86%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
I + + GYTMRDIRY W +G +SVG+SSEV LPQF+VLGHRQRA EI+LTTGNYSRLACE
Sbjct: 201 IEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYSRLACE 260
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG NAA
Sbjct: 261 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVLTMTTLMSSTNAA 320
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKK 244
LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF+AIQKIA +KK
Sbjct: 321 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFMAIQKIAEQKK 376
Score = 119 bits (287), Expect = 1e-25
Identities = 58/74 (78%), Positives = 63/74 (85%), Gaps = 4/74 (5%)
Query: 304 GGADEENPGP-HPIHPGK---DISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
GG D E P H +HPGK DI+KLLG+TPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV
Sbjct: 533 GGGDPEAAVPAHLLHPGKVKKDINKLLGITPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 592
Query: 360 SDVVANDLVLLEED 373
SDVVA+DLVLL E+
Sbjct: 593 SDVVADDLVLLGEE 606
Score = 86.2 bits (204), Expect = 1e-15
Identities = 39/49 (79%), Positives = 43/49 (87%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYT 77
GYTMRDIRY W+DG SSVGMS+EV+LPQFRVLGHRQRAT I LTT Y+
Sbjct: 207 GYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTGNYS 255
Score = 74.5 bits (175), Expect = 4e-12
Identities = 31/37 (83%), Positives = 32/37 (86%)
Query: 277 QEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
QEVRFKVHDPKAHSKGGTLENT+NGGRGG PGP
Sbjct: 475 QEVRFKVHDPKAHSKGGTLENTVNGGRGGPQSHGPGP 511
Score = 57.2 bits (132), Expect = 7e-07
Identities = 25/27 (92%), Positives = 26/27 (96%)
Query: 1 MFGDVNISAILDSFSISYDKRVRPNYG 27
M GDVNISAILDSFS+SYDKRVRPNYG
Sbjct: 53 MLGDVNISAILDSFSVSYDKRVRPNYG 79
>UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus
urticae|Rep: GABA receptor - Tetranychus urticae
(Two-spotted spider mite)
Length = 585
Score = 223 bits (545), Expect = 6e-57
Identities = 110/182 (60%), Positives = 129/182 (70%), Gaps = 2/182 (1%)
Query: 63 RQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNY 122
RQ+ I + + GY+M DI Y W + N+V + S + LPQF + RQ ISLTTGNY
Sbjct: 183 RQKCN-IEIESYGYSMTDIIYNWVD-ENAVKIDSNLMLPQFSIASIRQSWKYISLTTGNY 240
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
SRL CEIQ RSMGYY+IQIY+P+ LIVIISWVSFWL+RNATPARV LG
Sbjct: 241 SRLMCEIQLTRSMGYYMIQIYVPASLIVIISWVSFWLHRNATPARVHLGVITVLTMTTLM 300
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
N+ LPKISYVKSIDV+LGTCFVMVFA+LLEYA VGY+ KRI MRK RF + K A E
Sbjct: 301 SSTNSQLPKISYVKSIDVFLGTCFVMVFAALLEYAAVGYIGKRISMRKNRFQQLAKAAEE 360
Query: 243 KK 244
K+
Sbjct: 361 KR 362
Score = 85.0 bits (201), Expect = 3e-15
Identities = 39/75 (52%), Positives = 51/75 (68%), Gaps = 1/75 (1%)
Query: 289 HSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCF 348
H GG ++I G G N P K+++ L G++PSDIDKYSR+VFPVCFVCF
Sbjct: 504 HQPGGLSSSSI-GRIPGHFTTNLHRFTAVPPKNLNNLFGVSPSDIDKYSRVVFPVCFVCF 562
Query: 349 NLMYWIIYLHVSDVV 363
NLMYWII+LH+S ++
Sbjct: 563 NLMYWIIFLHISSIL 577
Score = 41.1 bits (92), Expect = 0.046
Identities = 20/49 (40%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYT 77
GY+M DI Y+W D ++V + + + LPQF + RQ I+LTT Y+
Sbjct: 194 GYSMTDIIYNWVD-ENAVKIDSNLMLPQFSIASIRQSWKYISLTTGNYS 241
>UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit
UNC-49B.3; n=11; Eumetazoa|Rep: Ionotropic GABA receptor
subunit UNC-49B.3 - Caenorhabditis elegans
Length = 506
Score = 173 bits (420), Expect = 8e-42
Identities = 115/323 (35%), Positives = 168/323 (52%), Gaps = 21/323 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSS----EVSLPQFKVLGHRQRAMEISLTTGNYSR 124
+ + + GY +DI Y W + + +++ LPQF+ + + ++G Y R
Sbjct: 183 LEIESYGYETKDIDYYWGKKRTDLEITAVKFDTFQLPQFQPTLYFVNTTKAETSSGKYVR 242
Query: 125 LACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXX 184
LA E+ VR+MG+Y + I IPS LIV ISWVSFWLNR A+PARV LG
Sbjct: 243 LALEVILVRNMGFYTMNIVIPSILIVTISWVSFWLNREASPARVGLGVTTVLTMTTLITT 302
Query: 185 XNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR--KQRFVAIQKIASE 242
N ++PK+SYVK +DV+L CFVMVFASLLEYA V YM KR+ +R K+R A Q+ +E
Sbjct: 303 TNNSMPKVSYVKGLDVFLNFCFVMVFASLLEYAIVSYMNKRLVLRREKRRKAAEQQQRNE 362
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKT-ISQEVRFKVHDPKAHSKGGTLEN---- 297
+ P + +M +S+ S P+K+ + ++ F H+ + EN
Sbjct: 363 MPMFNASPKAANNNSYEMTLMSQ--NSTPAKSYVQADLYFAGHNSSMNPLMEIPENCDCR 420
Query: 298 ---TINGGRGGADEENP-GPHPIHPGKDISKLL--GMTPSDIDKYSRIVFPVCFVCFNLM 351
+ R D + P P K SK TP+ IDK SR FP+ F FN++
Sbjct: 421 TIPMMQHPRLVTDGAHTLWPAPFARPKKASKTCCQRWTPAKIDKLSRYGFPLSFSIFNIV 480
Query: 352 YWIIYLHVSDVVANDLVLLEEDK 374
YW +Y+ + ++D + E DK
Sbjct: 481 YW-LYMKYLSLNSSDKI-QENDK 501
>UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit
beta-1 precursor (GABA(A) receptor subunit beta-1);
n=104; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit beta-1 precursor (GABA(A) receptor
subunit beta-1) - Homo sapiens (Human)
Length = 474
Score = 171 bits (416), Expect = 3e-41
Identities = 115/349 (32%), Positives = 174/349 (49%), Gaps = 22/349 (6%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 132 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ WN G +V +++ LPQF ++ ++ + ++ TTG Y RL+ + R++GY+++Q
Sbjct: 191 FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQT 250
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 251 YMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYL 310
Query: 203 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVG-DPHTLSKMN 261
CFV VF +LLEYA V Y+ +K+ + A+EK E V D H ++
Sbjct: 311 MGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLS 370
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKA-----HSKGGTLENTING--GRGGADEENPGPH 314
TL ++T EV V DPKA S ++ G A + + P
Sbjct: 371 TL-----EIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPS 425
Query: 315 PIHPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L P + IDK+SR+ FP+ F FN++YW+ Y+H
Sbjct: 426 KGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio
rerio|Rep: Glycine receptor, alpha 4b - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 536
Score = 166 bits (403), Expect = 9e-40
Identities = 100/295 (33%), Positives = 156/295 (52%), Gaps = 14/295 (4%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W +EGP V V+ ++ LPQF + + TG ++ + +
Sbjct: 233 LESFGYTMNDLIFQWLDEGP--VQVADDLMLPQFVLKEEKDLGYCTKHYNTGKFTCIEVK 290
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS L VI+SWVSFW+N +A PARV LG A+
Sbjct: 291 FHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRAS 350
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKK-LPE 247
LPK+SYVK+ID+++ C + VFA+LLEYA V +++++ K+ F +K+ E++
Sbjct: 351 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQY---KEFFRLRRKLRQEQRNRAA 407
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSK----TISQEVRFKVHDPKAHSKGGTLENTINGG- 302
G T +K N ++ PSR ++ ++E + + + G ++ +++G
Sbjct: 408 SGQAGAAETKNKSNNVTGGTPSRNAQRQCSACAREEQLASQNQDLYFPGFGIDTSLSGDG 467
Query: 303 -RGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A G P H DI + ID SR VFP+ F+ FN+ YW+ Y
Sbjct: 468 PLSEAAAMFAGLPPGHALFDIRRRFVEQAKRIDTISRAVFPLSFLVFNVFYWVTY 522
>UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subunit
beta-like precursor (GABA(A) receptor); n=11;
Protostomia|Rep: Gamma-aminobutyric acid receptor
subunit beta-like precursor (GABA(A) receptor) -
Drosophila melanogaster (Fruit fly)
Length = 496
Score = 160 bits (388), Expect = 6e-38
Identities = 101/305 (33%), Positives = 148/305 (48%), Gaps = 18/305 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + GYT+ D+ W P V + LPQF ++G+ + L TG Y RL+
Sbjct: 192 VEIESYGYTVSDVVMYWK--PTPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLS 249
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++GY++ Q Y+PS LIV++SWVSFW+N AT ARVALG ++
Sbjct: 250 FKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSS 309
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVG--YMAKRI--QMRKQRFVAIQKIASEKK 244
LP+ISYVK+ID+YL CFV VFA+LLEYA V Y KR +++K + KI ++
Sbjct: 310 LPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSER 369
Query: 245 LPECPPVGD-----PHTLSKMNTLSRCPPSRPSKTISQEV----RFKVHDPKAHSKGGTL 295
C D +S + +L R + +I E +F + G
Sbjct: 370 SETCSTTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMNLGKFPPSFRITRNYGTGH 429
Query: 296 ENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSD---IDKYSRIVFPVCFVCFNLMY 352
+ G H + G K D IDKYSR++FP+ F+ FNL Y
Sbjct: 430 SQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGY 489
Query: 353 WIIYL 357
W+ Y+
Sbjct: 490 WLFYI 494
>UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 513
Score = 158 bits (384), Expect = 2e-37
Identities = 114/325 (35%), Positives = 157/325 (48%), Gaps = 39/325 (12%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + GYT+ D+ W E P GV E LPQF ++G+ + L TG Y RL+
Sbjct: 191 VEIESYGYTVLDVVMSWKETPVR-GVD-EAKLPQFTIIGYETNDRKEKLATGIYQRLSLS 248
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++GY++ Q Y+PS LIV++SWVSFW+N AT ARVALG ++
Sbjct: 249 FKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSS 308
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATV-----GYMAKRIQMRKQ-----RFVAIQK 238
LP+ISYVK+ID+YL CFV VFA+LLEYA V G AK+ +K+ + + K
Sbjct: 309 LPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGARAKKKSKKKETEEEKKTICSSK 368
Query: 239 IASEKKLPECPPVGDPHTLSKMNT-LSRCPPSR-----------PSKTISQEVRF-KVHD 285
S+ P P D + + LS P R P S R ++HD
Sbjct: 369 TGSKASSP-FPGSTDADIIELQDLRLSPLPSIRNRSGLASGAATPGGPSSSGARLDQLHD 427
Query: 286 P-------KAHSKGGTLENTINGG---RGGADEENPGPHPIHPGKDISKLLGMTPSD--- 332
P + G + + G RG + H I G + K D
Sbjct: 428 PGKFPPSFRISRPPGYSTHAKSPGLRYRGTRHQRPKVLHAIKRGASVLKASMPKIKDVNL 487
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
IDKYSRI+FPV F+ FN YWI Y+
Sbjct: 488 IDKYSRIIFPVSFMLFNAGYWIFYV 512
>UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3
precursor; n=128; Euteleostomi|Rep: Glycine receptor
subunit alpha-3 precursor - Homo sapiens (Human)
Length = 464
Score = 148 bits (359), Expect = 2e-34
Identities = 99/295 (33%), Positives = 147/295 (49%), Gaps = 35/295 (11%)
Query: 68 VITLTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRL 125
++ L + GYTM D+ ++W +E P V V+ ++LPQF + + R TG ++ +
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCI 243
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG
Sbjct: 244 EVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGS 303
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKL 245
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ RF +K +E
Sbjct: 304 RASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-HKELLRFRRKRKNKTEA-- 360
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
L K S + EVR A+ G L+ + G
Sbjct: 361 ---------FALEKFYRFS---------DMDDEVRESRFSFTAYGMGPCLQ-----AKDG 397
Query: 306 ADEENPGPHPIH----PGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
+ P HP+ ++ K+ ID SR FP+ F+ FN+ YW+IY
Sbjct: 398 MTPKGPN-HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=3;
Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta) -
Caenorhabditis elegans
Length = 550
Score = 145 bits (351), Expect = 2e-33
Identities = 69/153 (45%), Positives = 92/153 (60%), Gaps = 1/153 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + GYT ++ KWN P +V + +PQF + G +S TG+Y RL+
Sbjct: 196 VEIESYGYTTSEVLMKWNY-PLAVHGVEQADVPQFTITGFHTEDSIVSTATGSYQRLSLV 254
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
Q RS+GY++ Q Y+P LIV++SWVSFW+N AT ARVALG +
Sbjct: 255 FQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRQS 314
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGY 221
LP+ISYVKSID+YL CFV VFA+LLEYA V Y
Sbjct: 315 LPRISYVKSIDIYLVMCFVFVFAALLEYAAVNY 347
Score = 50.0 bits (114), Expect = 1e-04
Identities = 19/27 (70%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
IDKYSR+VFPVCF+ FNL YW Y+ V
Sbjct: 522 IDKYSRVVFPVCFIVFNLFYWSYYMMV 548
>UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 525
Score = 144 bits (350), Expect = 3e-33
Identities = 73/174 (41%), Positives = 108/174 (62%), Gaps = 6/174 (3%)
Query: 53 QLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRA 112
Q P+ +L H R+++ VGYTM D+ ++W E +V VS ++LPQF + ++
Sbjct: 249 QRPRALILTHLSRSSL----PVGYTMNDLIFEWLEN-GAVQVSDGLTLPQFIMRDEKELG 303
Query: 113 MEIS-LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG 171
TG ++ + + R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG
Sbjct: 304 YCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALG 363
Query: 172 XXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
A+LPK+SYVK+ID+++ C + VFA+LLEYA V +++++
Sbjct: 364 ITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQ 417
Score = 36.7 bits (81), Expect = 0.98
Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 270 RPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGKD-ISKLLGM 328
R K +E RF T + T + A NP P P+ D + K
Sbjct: 430 RTQKADMREGRFNFASYHVSQPAPTKDGT--AVKNAAPAPNPQP-PVSRDMDTMRKKFVD 486
Query: 329 TPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
ID SR FP+ F+ FN+ YW+ Y
Sbjct: 487 RAKRIDTISRAAFPLAFLIFNVFYWVTY 514
>UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22;
Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens
(Human)
Length = 512
Score = 142 bits (343), Expect = 2e-32
Identities = 74/200 (37%), Positives = 112/200 (56%), Gaps = 4/200 (2%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM 222
CFV VF +LLEYA V Y+
Sbjct: 310 MGCFVFVFMALLEYALVNYI 329
Score = 39.1 bits (87), Expect = 0.18
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
ID++SRI FPV F FN++YW+ Y++
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYYVN 512
>UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subunit
rho-2 precursor (GABA(A) receptor subunit rho-2); n=99;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit rho-2 precursor (GABA(A) receptor subunit rho-2)
- Homo sapiens (Human)
Length = 465
Score = 141 bits (342), Expect = 2e-32
Identities = 88/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ ++SL QF + H + +TG Y+RL
Sbjct: 194 LELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 253
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG NA
Sbjct: 254 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNA 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SYVK++D+YL FV VF S+LEYA V Y+ +Q RK E+KL E
Sbjct: 314 SMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT-VQERK-----------ERKLRE 361
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
P SK L + +++ R + + + ++G A
Sbjct: 362 KFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAAR 421
Query: 308 EENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
++ + G+ ++ T + IDKYSR++FP ++ FNL+YW ++
Sbjct: 422 KKG-----LLKGQTGFRIFQNTHA-IDKYSRLIFPASYIFFNLIYWSVF 464
>UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 278
Score = 140 bits (339), Expect = 5e-32
Identities = 70/188 (37%), Positives = 108/188 (57%), Gaps = 5/188 (2%)
Query: 39 WKDGH--SSVGMSNEVQLP-QFRVLGHRQRATVITLTTVGYTMRDIRYKWNE--GPNSVG 93
W DG S+ +S P + ++ ++ + Y ++ +KWN+ G V
Sbjct: 91 WPDGRVFHSIRLSMTASCPMKLHSYPMDKQTCKLSFESFSYPSTELIFKWNKNRGNKEVQ 150
Query: 94 VSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIIS 153
VS E+ +PQF + ++ + + TTG+YSRL +F RS+G++LIQ YIP+ LIV++S
Sbjct: 151 VSDELQIPQFILTEYKTTSEFANFTTGSYSRLTVLFRFERSIGFFLIQTYIPAYLIVMLS 210
Query: 154 WVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 213
W++FW+N +TPAR+ LG A+LPK+SYVKSI+ +L CF+ VF SL
Sbjct: 211 WIAFWINHTSTPARIGLGITTVLTMTTLTNSARASLPKVSYVKSIEWFLIMCFLYVFMSL 270
Query: 214 LEYATVGY 221
+EY V Y
Sbjct: 271 VEYGCVSY 278
>UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 447
Score = 140 bits (338), Expect = 7e-32
Identities = 100/314 (31%), Positives = 149/314 (47%), Gaps = 41/314 (13%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y + ++ YKW +GP SV V+ E S L Q+ ++GH
Sbjct: 169 MQLEDFPMDAH---ACPLKFGSYAYPISEVVYKWTKGPGKSVVVAEEGSRLNQYHLIGHT 225
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+IS + G Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 226 AGTEDISTSRGQYTVMMAHFYLKRKIGYFVIQTYMPCFMTVILSQVSFWLNRESVPARTV 285
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 286 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR---- 341
Query: 230 KQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAH 289
+ K A E + P+ DP LSK P+ + I+++
Sbjct: 342 --SWAWDGKKALEAQQPK---KKDPLALSK-------KPNNFTANINKDAAI-------- 381
Query: 290 SKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFN 349
T+ N+ A E P P P +SK IDK SRIVFPV F FN
Sbjct: 382 ---STISNSTTVQLKSA-EAKPAPDPKKTYNSVSK--------IDKMSRIVFPVLFGTFN 429
Query: 350 LMYWIIYLHVSDVV 363
L+YW YL+ V+
Sbjct: 430 LVYWATYLNREPVI 443
>UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 469
Score = 140 bits (338), Expect = 7e-32
Identities = 93/303 (30%), Positives = 144/303 (47%), Gaps = 32/303 (10%)
Query: 69 ITLTTVGYTMRDIRYKWN--EGPNSVGVSSEVSL-PQFKVLGHRQRAMEISLTTGNYSRL 125
+ + + GY++ I YKW EG V +V L PQF + + GN+S +
Sbjct: 190 LIMESYGYSVEHIMYKWEKGEGDGMSFVPRDVKLLPQFNLTKLELSSRNTQYVIGNWSGV 249
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
F R+ +Y+I IY PS LIV+ISW+SF L R+ +PARV LG
Sbjct: 250 MATFTFERTYSFYVIHIYGPSALIVLISWISFLLPRDQSPARVTLGVTSVLTEVTILTMS 309
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKL 245
N A+PK++YVK++D YL CF+ VFASL+EY+ + +A R R+++ A +++A EK+
Sbjct: 310 NNAMPKVNYVKAVDKYLIACFLFVFASLMEYSLILVLANRTMRREKQKRAAKRLAMEKE- 368
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
C S P +S +R H S +L N G
Sbjct: 369 -NC---------------SEHDPENSKLLLSPNIRCACH---RRSPSSSLRN----ANGN 405
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSD-----IDKYSRIVFPVCFVCFNLMYWIIYLHVS 360
A + N + H + + + D +D+YSR +FP+ F FN+ YW++ S
Sbjct: 406 AHQPNFALNVTHRDSLLVSIRDILYRDETILAVDEYSRKLFPLAFFAFNVYYWVLVFWFS 465
Query: 361 DVV 363
++
Sbjct: 466 HLL 468
>UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 319
Score = 138 bits (335), Expect = 2e-31
Identities = 67/163 (41%), Positives = 93/163 (57%), Gaps = 3/163 (1%)
Query: 62 HRQRATVITLTTVGYTMRDIRYKWNE---GPNSVGVSSEVSLPQFKVLGHRQRAMEISLT 118
H ++ ++L + GY D+ Y WNE +++ + ++ LPQF+VLG + A
Sbjct: 157 HDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFEVLGVSRSAKMNKYN 216
Query: 119 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXX 178
GN+S L + R +GY+LI YIPS +IVIISW+SFW++ PARVALG
Sbjct: 217 IGNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITTVLTM 276
Query: 179 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY 221
A LPK+SYVK+ID YL C + VF S+LEY V Y
Sbjct: 277 TTLISSARANLPKVSYVKAIDWYLLLCLIFVFGSILEYTCVTY 319
>UniRef50_O17547 Cluster: GluClalpha2A protein; n=66;
Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis
elegans
Length = 657
Score = 137 bits (331), Expect = 5e-31
Identities = 66/164 (40%), Positives = 91/164 (55%), Gaps = 1/164 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
I L + YT +DI Y W E P + SLP F++ TG+YS L
Sbjct: 399 IDLASYAYTTKDIEYVWKEETPVQLKAGLSSSLPSFQLTNTSTTYCTSKTNTGSYSCLRT 458
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
IQ R YYL+Q+YIPS ++VI+SWVSFW++R A PARV LG NA
Sbjct: 459 IIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVTLGVTTLLTMTTQSSGINA 518
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 231
LP ++Y+K+IDV++G C +F +LLE+A V Y+A + K+
Sbjct: 519 KLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANKQDANKR 562
>UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 373
Score = 137 bits (331), Expect = 5e-31
Identities = 91/294 (30%), Positives = 151/294 (51%), Gaps = 29/294 (9%)
Query: 70 TLTTVGYTMRDIRYKWNEGPNS--VGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLA 126
++ + GY + D+ YKW G + + V +++L +F L Q +IS TG++S +
Sbjct: 102 SIESFGYPINDVVYKWRLGRSDEDIKVKQDLALTKF-TLWKIQTFTKISHYVTGSFSGIV 160
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
E R YY+IQI++P +IV +SW+SFW++ ++TPAR+ALG
Sbjct: 161 AEFTMTRRALYYVIQIFLPCAMIVFLSWISFWIDSHSTPARIALGITTVLSMTTLLFGVQ 220
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLP 246
++LPK+ YVKS+DVY+ F +VFASL+EYA V Y +K R A+ ++A ++K
Sbjct: 221 SSLPKVPYVKSLDVYMFVSFTLVFASLIEYACVHYNI----TKKDR--AVFQVAQQQKQT 274
Query: 247 EC-PPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
G+ T+ + + Q + FK+ G T +++
Sbjct: 275 HMEKATGNKETVRLLRRMK-----------GQSMNFKM--AAFGRLGPTSKSSTEAAAWS 321
Query: 306 ADEENPGPHPIHPGKDISKLLGMTP--SDIDKYSRIVFPVCFVCFNLMYWIIYL 357
A N P + GK + + P + +D+YSR++FP F+ FN++YW IY+
Sbjct: 322 A--VNLVPSAL-DGKSVPSDENLVPRVNLVDRYSRVLFPSFFLVFNIIYWPIYM 372
>UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit
gamma-3 precursor (GABA(A) receptor subunit gamma-3);
n=106; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit gamma-3 precursor (GABA(A) receptor
subunit gamma-3) - Homo sapiens (Human)
Length = 467
Score = 137 bits (331), Expect = 5e-31
Identities = 86/294 (29%), Positives = 146/294 (49%), Gaps = 16/294 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLA 126
+ ++ GY ++ Y+W + NSV + + S L QF +G R ++ + G+Y +
Sbjct: 187 LIFSSYGYPKEEMIYRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MGY+ IQ YIP L V++SWVSFW+ ++ATPAR ALG
Sbjct: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK-RIQMRKQRFVAIQKIASEKKL 245
+LP++SYV ++D+++ CF+ VFA+L+EYAT+ Y + R ++ ++ S + +
Sbjct: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 364
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
PE + P S + L PP T++ V ++ + + L+
Sbjct: 365 PERISLQAP---SNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYE--CLDGKDCQSFFC 419
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
EE G + + ++D YSR+ FP F+ FNL+YW+ YL++
Sbjct: 420 CYEE------CKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-3 precursor (GABA(A) receptor subunit alpha-3);
n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3) - Homo sapiens (Human)
Length = 492
Score = 136 bits (328), Expect = 1e-30
Identities = 85/285 (29%), Positives = 135/285 (47%), Gaps = 20/285 (7%)
Query: 76 YTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W G N SV V+ + S L Q+ +LGH I +TG Y + R
Sbjct: 214 YTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKR 273
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 274 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 333
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + + V + + +KK P P
Sbjct: 334 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVP-EALEMKKKTPAAPA--- 389
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
T + N + P ++++ F A + I + +++P
Sbjct: 390 KKTSTTFNIVGTTYPI----NLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTE 445
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ +SK +DK SRI+FPV F FNL+YW Y++
Sbjct: 446 TKTY--NSVSK--------VDKISRIIFPVLFAIFNLVYWATYVN 480
>UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to
gamma-aminobutyric acid A receptor beta 2S chain
precursor - chicken; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric
acid A receptor beta 2S chain precursor - chicken -
Strongylocentrotus purpuratus
Length = 418
Score = 135 bits (327), Expect = 2e-30
Identities = 69/199 (34%), Positives = 112/199 (56%), Gaps = 4/199 (2%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHR---QRATVITLTTVGYTMRDIR 82
+ V T + +R+H DG + GM + L H ++ + + + GYT D+
Sbjct: 54 HDVTVTNKLLRFH-HDGTITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVN 112
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W G +S+ + + + QF + ++ + +TG+Y RLA + R++G++ +Q
Sbjct: 113 FVWQYGDDSLEGVNNIEMAQFTLSDYKLIVKMQNFSTGSYPRLALTFRIKRNVGFFFLQT 172
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS L+V++SWVSFW+N AT ARV+LG +LP+ISYVKSID+Y+
Sbjct: 173 YLPSILLVMLSWVSFWINHEATSARVSLGITTVLTMTTISTAVRQSLPRISYVKSIDIYV 232
Query: 203 GTCFVMVFASLLEYATVGY 221
TC+ VFA+L+EYA V Y
Sbjct: 233 ITCYSFVFAALVEYAIVNY 251
Score = 40.3 bits (90), Expect = 0.080
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D+ SRI+FP F+ FN++YW+ YL+V
Sbjct: 384 VDRVSRILFPFLFLLFNVLYWVGYLYV 410
>UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3;
Chromadorea|Rep: GBR-2A protein precursor - Haemonchus
contortus (Barber pole worm)
Length = 421
Score = 134 bits (325), Expect = 3e-30
Identities = 65/168 (38%), Positives = 95/168 (56%), Gaps = 1/168 (0%)
Query: 68 VITLTTVGYTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLA 126
+I L + GYT +DI+Y+W E P SLP F++ + TG YS L
Sbjct: 193 LIDLASYGYTTQDIKYEWKEQNPVQQKDGLRQSLPSFELQDVVTKYCTSKTNTGEYSCLR 252
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
++ R YYL+Q+YIPS ++VI+SWVSFWL++++ PARV LG N
Sbjct: 253 TQMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGIN 312
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFV 234
A +P +SY K+IDV++G C +F +LLE+A V Y A++ QR +
Sbjct: 313 ANVPPVSYTKAIDVWIGVCLAFIFGALLEFAWVNYAARKDMSCGQRMM 360
Score = 41.5 bits (93), Expect = 0.035
Identities = 14/25 (56%), Positives = 20/25 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID SR+VFP+ + CFN++YW +YL
Sbjct: 396 IDVVSRLVFPIGYACFNVLYWAVYL 420
>UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to
glutamate-gated chloride channel; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to glutamate-gated
chloride channel - Nasonia vitripennis
Length = 510
Score = 131 bits (317), Expect = 2e-29
Identities = 63/156 (40%), Positives = 90/156 (57%), Gaps = 1/156 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + G+T D+ + W EG + V V + LP+F + TG YS L +
Sbjct: 180 LRMASYGWTTADLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVD 238
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ F R YYLIQIYIP ++VI+SWVSFWL+++A PARV+LG NA+
Sbjct: 239 LLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQSAVPARVSLGVTTLLTMATQTSGINAS 298
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LP +SY K+IDV+ G C VF +LLE+A V Y ++
Sbjct: 299 LPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASR 334
Score = 35.9 bits (79), Expect = 1.7
Identities = 14/25 (56%), Positives = 17/25 (68%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID +RI+FP+ F FNL YW YL
Sbjct: 417 IDVIARIIFPLVFALFNLAYWSTYL 441
>UniRef50_Q94900 Cluster: Glutamate-gated chloride channel
precursor; n=21; Pancrustacea|Rep: Glutamate-gated
chloride channel precursor - Drosophila melanogaster
(Fruit fly)
Length = 456
Score = 131 bits (317), Expect = 2e-29
Identities = 63/156 (40%), Positives = 89/156 (57%), Gaps = 1/156 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + G+T D+ + W EG + V V + LP+F + TG YS L +
Sbjct: 179 LRMASYGWTTNDLVFLWKEG-DPVQVVKNLHLPRFTLEKFLTDYCNSKTNTGEYSCLKVD 237
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ F R YYLIQIYIP ++VI+SWVSFWL++ A PARV+LG NA+
Sbjct: 238 LLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINAS 297
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LP +SY K+IDV+ G C VF +LLE+A V Y ++
Sbjct: 298 LPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASR 333
Score = 36.7 bits (81), Expect = 0.98
Identities = 15/25 (60%), Positives = 17/25 (68%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID SRI FP+ F FNL+YW YL
Sbjct: 425 IDVISRITFPLVFALFNLVYWSTYL 449
>UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor;
n=34; Euteleostomi|Rep: Glycine receptor subunit beta
precursor - Homo sapiens (Human)
Length = 497
Score = 130 bits (313), Expect = 8e-29
Identities = 96/306 (31%), Positives = 148/306 (48%), Gaps = 28/306 (9%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLAC 127
L + GYT D+R+ W G + V + +++LPQF + + TG Y+ +
Sbjct: 201 LESFGYTTDDLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R +G+Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQ----KIA 240
LPK+SYVK++DV+L C + FASL+EYA V M KR++ K R + K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 241 SEKKLPECPPVGDPHTLSKMNT-LSRCPPSRPSKTISQEVRFKVHD--PKAHS------K 291
+ K G P +S + +RC SK+ + F + P+
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 292 GGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLM 351
G +E +N G G + +N P P K + + ID Y+R +FP CF+ FN++
Sbjct: 439 GKPIE--VNNGLGKSQAKNNKKPP--PAKPV---IPTAAKRIDLYARALFPFCFLFFNVI 491
Query: 352 YWIIYL 357
YW IYL
Sbjct: 492 YWSIYL 497
>UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 6
isoform 1 - Pan troglodytes
Length = 478
Score = 129 bits (311), Expect = 1e-28
Identities = 87/284 (30%), Positives = 135/284 (47%), Gaps = 23/284 (8%)
Query: 76 YTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
Y +I Y W +GP SV V E S L Q+ ++G + I TG Y + R
Sbjct: 204 YPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQR 263
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
MGY++IQIY P + VI+S VSFW+N+ + PAR G +LPK+S
Sbjct: 264 KMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVS 323
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ CF VF++L+E+A V Y +Q +K + A +IA+ +
Sbjct: 324 YATAMDWFIAVCFAFVFSALIEFAAVNYFT-NLQTQKAKRKA--QIAAPPSVTISKATEP 380
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
++ S+ + ++S + K ++ L++T
Sbjct: 381 LEAEIVLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQST--------------- 425
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
P+ P +S G T S ID+YSRI+FPV F FNL+YW++YL
Sbjct: 426 -PVTP-PPLSPAFGGT-SKIDQYSRILFPVAFAGFNLVYWVVYL 466
>UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=2; Euteleostomi|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 481
Score = 128 bits (308), Expect = 3e-28
Identities = 85/283 (30%), Positives = 137/283 (48%), Gaps = 11/283 (3%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNYSRLACEIQFVR 133
GY+ DI Y W+E V ++ L QF + +R M + G + RL+ Q R
Sbjct: 207 GYSSEDIVYHWSESQQHVHGLDKLELSQFTITDYRFDTEMMNFKSAGRFPRLSLCFQLRR 266
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+ G Y+IQ Y+PS L+V +SWVSFW++++A PARV LG ++LP+ S
Sbjct: 267 NRGVYIIQSYMPSILLVAMSWVSFWISQSAVPARVTLGITTVLTMTTLMVSARSSLPRAS 326
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
+K++DVY C+V VFA+L+EYA Y A +++++ V K++SE V +
Sbjct: 327 AIKALDVYFWICYVFVFAALIEYAFAHYNAD-YRLKEKAKVKASKLSSES------IVKN 379
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
+ +LS ++ +++ R + + + + E R EE P
Sbjct: 380 GKQAMVLFSLSVTGMNQSVMISNRQGRAQRSSSEIPGEAASEEAEPRRRRSKQTEE-PKE 438
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
K + K + ID Y+R VFP F N++YW+ Y
Sbjct: 439 EKKCCSKCVCK--PIDADTIDIYARAVFPFTFAVVNVIYWVAY 479
>UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis
mellifera|Rep: GABA-gated ion channel - Apis mellifera
(Honeybee)
Length = 463
Score = 125 bits (302), Expect = 2e-27
Identities = 91/303 (30%), Positives = 146/303 (48%), Gaps = 19/303 (6%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFV 132
GYT RD+ YKWN V ++ ++ L QF ++ + S T + YS L
Sbjct: 152 GYTKRDVIYKWNSA-RQVAIAEDMKLSQFDLVANPTANYSASTTLSHAEYSMLLVYFHLQ 210
Query: 133 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKI 192
R MG +LIQ+Y P L+V++SWVSFWLNR AT RV+LG LPK+
Sbjct: 211 RHMGNFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKV 270
Query: 193 SYVKSIDVYLGTCFVMVFASLLEYATVGYMAK--RIQMRKQRFVAIQKIASEKKLPECPP 250
Y ++D ++ F +FA+++++A V Y K + ++ + +S+++ + P
Sbjct: 271 PYPTALDFFVFLSFAFIFATIIQFAVVHYFTKYGSGECYFSSDLSESETSSDEEEADTRP 330
Query: 251 V-GDPHTLSKM----NTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
+ +P T S N +R PSR + T+S++ +V P + + + +
Sbjct: 331 LKKEPITQSNKRTAGNLATREHPSR-NFTMSEDGMIEV-IPLSAIPEPSKNPAMGHWQMS 388
Query: 306 ADEENPGPHPIHPGKDIS--KLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+P P P + S + TP S ID+ SRIVFP+ F+ N+ YW YL
Sbjct: 389 CVACSPPPRQTPPSRKESGRRRRRRTPRYNSVSKIDRASRIVFPLFFLAINVFYWFAYLS 448
Query: 359 VSD 361
S+
Sbjct: 449 RSE 451
>UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subunit
beta precursor; n=8; Chromadorea|Rep: Glutamate-gated
chloride channel subunit beta precursor - Caenorhabditis
elegans
Length = 434
Score = 124 bits (300), Expect = 3e-27
Identities = 67/170 (39%), Positives = 92/170 (54%), Gaps = 2/170 (1%)
Query: 71 LTTVGYTMRDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLT-TGNYSRLACE 128
L + +TM DI Y+W+ P + LP F + + A S T TG+Y L +
Sbjct: 179 LVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCTSHTNTGSYGCLRMQ 238
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ F R YYL+Q+Y P+ +IVI+SWVSFW++ ++T RVALG NA
Sbjct: 239 LLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAK 298
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQK 238
LP +SYVK +DV+LG C VF +LLEYA V Y Q + R A +K
Sbjct: 299 LPPVSYVKVVDVWLGACQTFVFGALLEYAFVSYQDSVRQNDRSREKAARK 348
Score = 37.1 bits (82), Expect = 0.74
Identities = 14/31 (45%), Positives = 22/31 (70%)
Query: 330 PSDIDKYSRIVFPVCFVCFNLMYWIIYLHVS 360
P+ ID Y+R V P+ F+ FN++YW+ L +S
Sbjct: 394 PAKIDFYARFVVPLAFLAFNVIYWVSCLIMS 424
>UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta); n=18;
Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta) - Homo
sapiens (Human)
Length = 632
Score = 124 bits (299), Expect = 4e-27
Identities = 56/159 (35%), Positives = 90/159 (56%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
++A + + + GYT+ DI W++ N++ ++ E+ +PQF LG + E+ TG+Y
Sbjct: 194 KQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYI 253
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
RL + Q R + YL+Q+Y P+ L I SW+SFW+N +++ ARV +G
Sbjct: 254 RLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDS 313
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
LP IS +K+ID+Y+ C VF SLLEY + Y+
Sbjct: 314 HLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYL 352
Score = 38.7 bits (86), Expect = 0.24
Identities = 18/63 (28%), Positives = 31/63 (49%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEG 88
GYT+ DI W D +++ M+ E+ +PQF LG + + T Y ++++
Sbjct: 205 GYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQRE 264
Query: 89 PNS 91
NS
Sbjct: 265 VNS 267
Score = 37.5 bits (83), Expect = 0.56
Identities = 11/26 (42%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+DK+SR +FP+ F FN++YW+ +++
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYWVYHMY 632
>UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit
delta precursor (GABA(A) receptor subunit delta); n=27;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit delta precursor (GABA(A) receptor subunit delta)
- Homo sapiens (Human)
Length = 452
Score = 124 bits (299), Expect = 4e-27
Identities = 80/295 (27%), Positives = 137/295 (46%), Gaps = 21/295 (7%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNY 122
++ ++ L + GY+ DI Y W+E + ++ L QF + +R ++ + G +
Sbjct: 175 EQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQF 234
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
RL+ R+ G Y+IQ Y+PS L+V +SWVSFW+++ A PARV+LG
Sbjct: 235 PRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLM 294
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
++LP+ S +K++DVY C+V VFA+L+EYA + A + +K + V + + +E
Sbjct: 295 VSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK-VKVSRPRAE 353
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTI-NG 301
+ + +LS SR + + + + E +G
Sbjct: 354 MDVRNAIVL---FSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSG 410
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G+GG ++L + ID Y+R VFP F N++YW Y
Sbjct: 411 GQGGIR---------------ARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated
chloride-ion channel/receptor, zeta subunit precursor;
n=1; Lymnaea stagnalis|Rep: Gamma-aminobutyric
acid-grated chloride-ion channel/receptor, zeta subunit
precursor - Lymnaea stagnalis (Great pond snail)
Length = 437
Score = 124 bits (298), Expect = 5e-27
Identities = 59/142 (41%), Positives = 86/142 (60%), Gaps = 2/142 (1%)
Query: 86 NEGPNSVGVSSEVSLPQFKVLGHRQRAME--ISLTTGNYSRLACEIQFVRSMGYYLIQIY 143
N ++ V SEV LPQF+V GN+S + E R++G+Y++Q+Y
Sbjct: 210 NPDGKAIVVDSEVLLPQFEVKSVIPSFCNRRYHQKAGNHSCIQAEFHLARNIGFYIVQMY 269
Query: 144 IPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLG 203
IPS LIV++SW+SFWL N+ P RV+LG NAALP++SY K+IDV++
Sbjct: 270 IPSMLIVMLSWISFWLTVNSVPGRVSLGLLTVLTMTTQSSSVNAALPRVSYTKAIDVWMS 329
Query: 204 TCFVMVFASLLEYATVGYMAKR 225
TC V VFA+LLE+A V ++++
Sbjct: 330 TCLVFVFAALLEFAVVNVLSRK 351
Score = 37.9 bits (84), Expect = 0.43
Identities = 11/26 (42%), Positives = 20/26 (76%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+D +R+VFP+CF+ F + YW+ Y++
Sbjct: 410 VDMTARVVFPICFIIFIMSYWLYYVN 435
>UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12;
Endopterygota|Rep: CG14723-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 426
Score = 122 bits (294), Expect = 2e-26
Identities = 59/164 (35%), Positives = 91/164 (55%), Gaps = 1/164 (0%)
Query: 56 QFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEI 115
+F H + + + ++ +T+ D+ + WN V V++E+ LPQ + + I
Sbjct: 185 KFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLV-VNTEIELPQLDISNNYTTDCTI 243
Query: 116 SLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXX 175
+TGN++ LA R +GY+L YIPS LIV++SW+SFW+ A PARV LG
Sbjct: 244 EYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSL 303
Query: 176 XXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
+LP +SYVK+IDV++ +C V VF SL+E+A V
Sbjct: 304 LTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVV 347
Score = 33.5 bits (73), Expect = 9.2
Identities = 12/25 (48%), Positives = 16/25 (64%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
IDK+SR FP F N++YW +L
Sbjct: 402 IDKFSRFFFPFSFFILNIVYWTTFL 426
>UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protein
4; n=2; Caenorhabditis|Rep: Glutamate-gated chloride
channel protein 4 - Caenorhabditis elegans
Length = 500
Score = 121 bits (291), Expect = 4e-26
Identities = 56/170 (32%), Positives = 90/170 (52%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
I + YT DI Y W+ + + +LP F++ + + TG YS L E
Sbjct: 198 IAFASYAYTTADIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSKTNTGTYSCLKVE 257
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
I+ R ++L+Q+YIPS ++V ++WVS+W++ +T ARV L N+
Sbjct: 258 IRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTSHAINSN 317
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQK 238
LP +SY KSID+++G C V +F SL+EYA V Y+ + R+ + A +
Sbjct: 318 LPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKKAACNR 367
Score = 39.1 bits (87), Expect = 0.18
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHVSD 361
ID +RI+FP+ F+ FN YW IYL D
Sbjct: 468 IDIIARIIFPLAFILFNFAYWSIYLEEED 496
>UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated
chloride channel; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to GABA-gated
chloride channel - Strongylocentrotus purpuratus
Length = 530
Score = 119 bits (287), Expect = 1e-25
Identities = 97/348 (27%), Positives = 158/348 (45%), Gaps = 46/348 (13%)
Query: 63 RQRATVITLTTVGYTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN 121
+QR + + + + Y+ D+++KW E GP V V ++SLPQFK L R+ GN
Sbjct: 183 KQRCS-LDMESYAYSEDDVKFKWLENGP--VYVDPKISLPQFKFLDSSVRSRIAEYFVGN 239
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXX 181
Y+ ++ + R + YY++Q YIPS +I +SW+SFW+NRNA PARVALG
Sbjct: 240 YTVVSADFYLGRDITYYVVQTYIPSSMITCLSWLSFWINRNAVPARVALGITTVLTMTTL 299
Query: 182 XXXXNAALPKIS--------------------YV---KSIDVYLGT-CFVMVFASLLEYA 217
+LPK+S YV + + Y+ + C+ VFA+LLEY
Sbjct: 300 VGNAGNSLPKLSYIKAIDLFLGMFLQQTGSMSYVTMNRGMFYYVNSMCYFFVFAALLEYV 359
Query: 218 TVGYMA----KRIQMRKQRFVAIQKIASEKKLPECPPV-------GDPHTLSKMN----T 262
V Y K+ + + F + A+++ V G + S+ N T
Sbjct: 360 IVIYYDQPRYKKARELMKEFQDHEHAANKEDSARTNDVAIAIDDEGTSKSRSEQNGRTST 419
Query: 263 LSRCPPSRP--SKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGK 320
S RP S+ I++ ++ + G LE + +E +
Sbjct: 420 SSSRDHRRPPTSQDINRSLQLDAMRKAGDADCGFLEGKVETEEPDCMQETLCSFAQSIRE 479
Query: 321 DISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVANDLV 368
+ + G P +DK +R+ FP+ F NL+YW++YL ++ DL+
Sbjct: 480 KVC-VFGFNPYSVDKVARVAFPLTFFSLNLVYWLVYLVFDNITLEDLM 526
>UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1;
Aplysia californica|Rep: GABA A receptor alpha subunit -
Aplysia californica (California sea hare)
Length = 448
Score = 115 bits (277), Expect = 2e-24
Identities = 54/157 (34%), Positives = 86/157 (54%), Gaps = 1/157 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEG-PNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
+ + + Y+ D+ YKW G S+ ++ ++ L QF ++G+ + +S L
Sbjct: 174 LLIGSFAYSTDDVIYKWRYGLQGSIELAPDLRLSQFDLVGYPLTNYTGLVKGAVHSVLCV 233
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
Q R GY+LI +Y+P L+V++SW SFW+NR AT R+ALG +
Sbjct: 234 TFQLSRHTGYFLINLYLPCCLLVVLSWASFWINREATADRIALGSTTVLTMTILGIENKS 293
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LPK+SY+ ++DVY+ CFV V A+ +E+A V Y K
Sbjct: 294 QLPKVSYITALDVYVALCFVFVIATTIEFAVVHYFTK 330
Score = 33.9 bits (74), Expect = 6.9
Identities = 14/23 (60%), Positives = 17/23 (73%)
Query: 5 VNISAILDSFSISYDKRVRPNYG 27
VNIS +LDS YDKR+RP +G
Sbjct: 32 VNISQVLDSLLEGYDKRLRPGFG 54
>UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 424
Score = 115 bits (276), Expect = 2e-24
Identities = 57/156 (36%), Positives = 87/156 (55%), Gaps = 2/156 (1%)
Query: 69 ITLTTVGYTMRDIRYKW-NEGPNSVGVSSEV-SLPQFKVLGHRQRAMEISLTTGNYSRLA 126
I + + GY+ +++Y+W N N + V+ ++ +PQ+ + GN+S L
Sbjct: 145 IDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQYNLSDINVSRHFTMYVAGNWSGLT 204
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+F R GY++I IY P LIVI+SW+SF + +T AR+ALG N
Sbjct: 205 ATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTITTILNMLN 264
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
++PK+SYVK++D YL CF+ VFA LLEY V Y+
Sbjct: 265 NSMPKVSYVKAVDWYLIGCFLFVFAVLLEYTFVLYI 300
Score = 35.5 bits (78), Expect = 2.3
Identities = 10/27 (37%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
ID+++R++FP F+ FN++Y+I++ +
Sbjct: 392 IDEFARVLFPFIFIAFNVIYFIVFFFI 418
>UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 293
Score = 114 bits (275), Expect = 3e-24
Identities = 55/157 (35%), Positives = 91/157 (57%), Gaps = 3/157 (1%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR-QRAMEISLTTGNY 122
Q+ V+ + + + + DI Y+W + + + E++ +F++ R +R + TG Y
Sbjct: 139 QQTCVLEILSYSFDINDIDYRWKAKEDLIILDGEMN--EFELKDSRGERKQKSRSCTGTY 196
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
+ L + F R + Y IQIY P+ LIV++SW+SFW++++A PARVALG
Sbjct: 197 THLVAKFVFRRRLAYSFIQIYSPTFLIVVLSWLSFWISKDAVPARVALGITTVLTIVTLM 256
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
++PK+SY+K+ID+YL F+ VF +LLEY V
Sbjct: 257 GSLRNSVPKVSYIKAIDLYLIVSFIFVFGTLLEYIAV 293
>UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit
pi precursor (GABA(A) receptor subunit pi); n=19;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit pi precursor (GABA(A) receptor subunit pi) -
Homo sapiens (Human)
Length = 440
Score = 114 bits (275), Expect = 3e-24
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.14
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 442
Score = 114 bits (274), Expect = 4e-24
Identities = 55/150 (36%), Positives = 81/150 (54%), Gaps = 1/150 (0%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
GYT RD+ YKWN V ++ ++ L QF ++G+ S + YS L R
Sbjct: 196 GYTTRDVIYKWNSA-RQVAIAHDMKLSQFDLVGNPTANATDSTLSQKYSMLLVSFHLKRH 254
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISY 194
MG +LIQ+Y P L+V++SWVSFWLNR AT RV+LG LPK+ Y
Sbjct: 255 MGNFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFLGLEARTDLPKVPY 314
Query: 195 VKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
++D ++ F +FA+++++A V Y K
Sbjct: 315 PTALDFFVFLSFGFIFATIIQFAVVHYFTK 344
Score = 38.3 bits (85), Expect = 0.32
Identities = 15/27 (55%), Positives = 19/27 (70%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYL 357
S ID+ SR+VFP+ F+ NL YW YL
Sbjct: 407 SKIDRASRLVFPLFFLAINLFYWFAYL 433
>UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-4 precursor (GABA(A) receptor subunit alpha-4);
n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-4 precursor (GABA(A) receptor subunit
alpha-4) - Homo sapiens (Human)
Length = 554
Score = 113 bits (273), Expect = 5e-24
Identities = 62/183 (33%), Positives = 94/183 (51%), Gaps = 6/183 (3%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y ++ Y W +GP SV V E S L Q+ ++G
Sbjct: 174 MRLVDFPMDGH---ACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQT 230
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQ YIP + VI+S VSFW+N+ + PAR
Sbjct: 231 VSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTV 290
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
G +LPK+SY+ ++D ++ CF VF++L+E+A V Y IQM
Sbjct: 291 FGITTVLTMTTLSISARHSLPKVSYLTAMDWFIAVCFAFVFSALIEFAAVNYFT-NIQME 349
Query: 230 KQR 232
K +
Sbjct: 350 KAK 352
Score = 47.2 bits (107), Expect = 7e-04
Identities = 18/31 (58%), Positives = 24/31 (77%)
Query: 327 GMTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
G S IDKY+RI+FPV F FN++YW++YL
Sbjct: 512 GSGTSKIDKYARILFPVTFGAFNMVYWVVYL 542
>UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 513
Score = 113 bits (271), Expect = 9e-24
Identities = 86/315 (27%), Positives = 149/315 (47%), Gaps = 44/315 (13%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLA 126
+ ++D+ W+E P + ++ E+ L +++++ E+S TT GN+S ++
Sbjct: 201 HNVQDMILNWDEAP--IVLADELHLTEYRLVEQWVNRSEVSYTTAQQHYGHFAGNFSSIS 258
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MG++++ YIPS LIV+ISWVSFWL+ +A+P R+ LG
Sbjct: 259 ITFKLAREMGFFMMDYYIPSILIVVISWVSFWLHVDASPPRIVLGTNTILAFMTLASKVE 318
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLP 246
+LPK+SY+K+ +++ C + +FA+++E+A V + R+++ V ++K+ S+ L
Sbjct: 319 NSLPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTI-----YRRKKNVPLKKVNSKYILK 373
Query: 247 ECPPVGDPHTLSKMNTL----SRCPPSRPSKTISQEVRFKVHDPKAHSKGGTL------- 295
+ NT SR S + +S++ + HS T+
Sbjct: 374 STLTPRLARKQFQKNTTGIERSRSWSSLDNGNVSEKDYTSQNYLTIHSFPSTINVPAVRI 433
Query: 296 --ENTINGGRGGADEENPGPHPIHPG-----------KDISKLLGMTPSD----IDKYSR 338
E + G + NP P P P ++ MTP IDK R
Sbjct: 434 DDEKDYSIGSVVTIDSNPSPPPPAPPVAKPFQRRGTLARLNTFTTMTPQQIAQWIDKRCR 493
Query: 339 IVFPVCFVCFNLMYW 353
IVFPV F+ FN++YW
Sbjct: 494 IVFPVSFLIFNILYW 508
>UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 304
Score = 113 bits (271), Expect = 9e-24
Identities = 56/151 (37%), Positives = 81/151 (53%), Gaps = 2/151 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+++ + Y +R + Y+W P + E+S QF + G YS L
Sbjct: 142 LSIISYAYPVRHLLYRWKNSPGIKVLDGEMS--QFYMTRITTSLRNEIYVAGEYSVLKAS 199
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R +G+YLIQIYIP IV ++W+S W++R ATPARV+L NA+
Sbjct: 200 FTFQRRVGFYLIQIYIPCMAIVFVAWMSLWVDRRATPARVSLCITTLLTIATIWGNVNAS 259
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
+P++SYVKSID+YL T F V +LLEY +
Sbjct: 260 MPRVSYVKSIDIYLMTSFTFVLGTLLEYIVI 290
>UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 112 bits (270), Expect = 1e-23
Identities = 49/148 (33%), Positives = 84/148 (56%)
Query: 70 TLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEI 129
T ++ Y +D+ Y+W + P ++ SS++ + + ++ + TG Y+ L +
Sbjct: 144 TFSSFSYNDKDLVYEWMKNPPALEFSSQLRMAHYDLIEWSTESKLDEFVTGKYASLTAKF 203
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
F R + +Y++ +IP+ IVI+SWV FW++ + PARV+LG + L
Sbjct: 204 VFKRRVRFYILSAFIPAAFIVILSWVGFWIDERSVPARVSLGITTVLAITTLIFGVQSTL 263
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYA 217
P++ Y+K+IDVYL F+ VFASL+EYA
Sbjct: 264 PRVGYIKAIDVYLLGNFLFVFASLVEYA 291
>UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 564
Score = 112 bits (270), Expect = 1e-23
Identities = 63/171 (36%), Positives = 94/171 (54%), Gaps = 11/171 (6%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVL--------GHRQRAM-E 114
Q+ I + + Y + + W + N V + E+ LP+F++ G Q A+ E
Sbjct: 162 QQLCSIRVLSYAYIAKQVNVTWFD-KNPVRFNEEIGLPEFQIEHVSNAYCNGSYQYALTE 220
Query: 115 ISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXX 174
S + ++S L+ + RS+GY L+Q YIP+GLIV+ISWVSFW++R A PARV L
Sbjct: 221 NSYKSDDFSCLSGNLFLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVPARVTLSFTT 280
Query: 175 XXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV-GYMAK 224
LP++SY K+ID++ G C VF +LLE+AT+ YM K
Sbjct: 281 LVSLTTLGNGLRFGLPQVSYAKAIDLWYGACMFFVFCALLEFATINSYMRK 331
>UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-5 precursor (GABA(A) receptor subunit alpha-5);
n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-5 precursor (GABA(A) receptor subunit
alpha-5) - Homo sapiens (Human)
Length = 462
Score = 112 bits (270), Expect = 1e-23
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 5/176 (2%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y ++ Y W G SV V+ + S L Q+ ++G
Sbjct: 175 MQLEDFPMDAH---ACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
IS +TG Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 232 VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTV 291
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 292 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 347
Score = 44.4 bits (100), Expect = 0.005
Identities = 20/33 (60%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S IDK SRIVFPV F FNL+YW YL+ V+
Sbjct: 423 SKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 538
Score = 112 bits (269), Expect = 2e-23
Identities = 52/154 (33%), Positives = 83/154 (53%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 135
+ + +R W V +V LP F + G + +L ++ F RS
Sbjct: 238 FNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAGVWDQLNIKLLFRRSY 297
Query: 136 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYV 195
G+Y++QIY+P+ +V+ISW+SFWL+R + PARV LG + +LPK+SYV
Sbjct: 298 GFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNVSRSLPKVSYV 357
Query: 196 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
K +D+++ C V +F S++E A VG + +R Q R
Sbjct: 358 KGLDLFMFGCIVYIFLSIVELAVVGSLEQRKQQR 391
Score = 33.5 bits (73), Expect = 9.2
Identities = 11/28 (39%), Positives = 19/28 (67%)
Query: 329 TPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
T D+D++ + +FP+ F NL+YW+ Y
Sbjct: 505 TAEDMDRFCQKLFPITFTFCNLIYWMYY 532
>UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subunit;
n=2; Apis mellifera|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 469
Score = 112 bits (269), Expect = 2e-23
Identities = 81/302 (26%), Positives = 143/302 (47%), Gaps = 26/302 (8%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT---------GNYSRLA 126
+ + D+ W++ P + ++ E+ L ++K++ + EI TT GN+S ++
Sbjct: 165 HNVLDMVLYWDQEP--IILADELHLTEYKLVEKWVNSSEIFYTTSQQYYGHFAGNFSSIS 222
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MG++++ YIPS LIV+ISWVSFWL+ +A+P R+ LG
Sbjct: 223 ITFKLAREMGFFMMDYYIPSILIVVISWVSFWLHMDASPPRIVLGTNTILTFMTLASKVE 282
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR---IQMRKQRFVAIQKIASEK 243
+LPK+SY+K+ +++ C + +FA+++E+A V + +R + ++K I K
Sbjct: 283 NSLPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTIYRRKKTVPLKKVNSKYILKSTLTP 342
Query: 244 KLPECPPVGDPHTLSKMNTLSRCPPSRPS-KTISQEVRFKVHD-PKAHSKGGT-----LE 296
KL + L + + S + + + S + VH P + +
Sbjct: 343 KLARKQFQKNTTGLERSRSWSSLDNTNTNDQDYSSQNYLTVHSFPSTLNIPSVKIDEDQK 402
Query: 297 NTINGGRGGADEENPGPHPIHPG-KDISKLLGMTPSD----IDKYSRIVFPVCFVCFNLM 351
+I +P P P + MTP + ID+ SRIVFPV F+ FN++
Sbjct: 403 CSIESITSVNSTSSPKPFPRRATLAQLHNFTTMTPQEIAQWIDRRSRIVFPVAFIIFNIL 462
Query: 352 YW 353
YW
Sbjct: 463 YW 464
>UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3;
Rhabditida|Rep: GABA A/glycine receptor subunit -
Haemonchus contortus (Barber pole worm)
Length = 472
Score = 111 bits (268), Expect = 2e-23
Identities = 60/170 (35%), Positives = 96/170 (56%), Gaps = 6/170 (3%)
Query: 65 RATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS--LTTG-N 121
+A I + ++GY D+ Y W + + + +S Q+K+LG + S G N
Sbjct: 176 QACPIEIGSLGYFSNDVVYYWKDVELDAKMGNMLS--QYKILGLFKSEHNFSDHREIGRN 233
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXX 181
S L + R GYY++QIY P L+V++SWVSFW+N+ A+PARVALG
Sbjct: 234 ISVLKVYFKLQRQQGYYVLQIYTPCTLLVVMSWVSFWINKEASPARVALGIMTVLSMSTL 293
Query: 182 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 231
LPK+S+ ++D+Y+ +CF VFA+++EY+ + Y A+ + +RKQ
Sbjct: 294 GFGLRTDLPKVSHSTALDIYILSCFGFVFAAMVEYSVINY-AQIVYIRKQ 342
Score = 36.3 bits (80), Expect = 1.3
Identities = 10/26 (38%), Positives = 20/26 (76%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+D S+++FP +V FN++YW+ +L+
Sbjct: 430 VDDVSKVIFPSLYVLFNILYWVAFLY 455
>UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 366
Score = 111 bits (267), Expect = 3e-23
Identities = 52/154 (33%), Positives = 86/154 (55%), Gaps = 3/154 (1%)
Query: 68 VITLTTVGYTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAM-EISLTTGNYSRL 125
V+ + + YT+ D+ Y WN G + + + + QF + + M SL TG++ L
Sbjct: 98 VLKIESYAYTVEDVIYNWNNRGTTPIEIFAG-EMAQFDMTEMTMQTMITFSLLTGSFDSL 156
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+F R Y+++Q Y+PS IV +SW+ FW+N+NA PAR++L
Sbjct: 157 RVSFRFKRRTSYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESI 216
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
N++LP+ISY+K++D YL F+ + AS++EY V
Sbjct: 217 NSSLPRISYLKAVDYYLIISFMFILASMVEYVLV 250
>UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 111 bits (266), Expect = 4e-23
Identities = 51/155 (32%), Positives = 84/155 (54%), Gaps = 2/155 (1%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLP--QFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + G+TM+D+ YKW + P + + L +F ++ + GN+S L
Sbjct: 148 IESYGFTMKDVVYKWLDDPKQKTIETAEGLDATEFSIVSLKTMENISVFNLGNFSSLTMR 207
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
I R YY+IQIYIP +IV++SW+SFWL+ + PAR ALG ++
Sbjct: 208 IYLDRRTTYYVIQIYIPCSMIVMLSWISFWLDYKSVPARTALGITTVLAMTTLLFGIQSS 267
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMA 223
LP + Y+K++D +L F VF +L+E+A V +++
Sbjct: 268 LPGVPYIKAVDQFLIVSFACVFVALIEFAVVNFIS 302
>UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;
n=2; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 534
Score = 109 bits (263), Expect = 9e-23
Identities = 81/301 (26%), Positives = 134/301 (44%), Gaps = 20/301 (6%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLT------TGNYSRLACEI 129
Y ++ W++ N V ++ + L +F + G + + + GN+S L +
Sbjct: 234 YNTTNLILHWDKN-NPVKIAKNLHLTEFVLSGSLPQETVVPASFNNGAFVGNFSELVFKF 292
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
R +GYY++ ++PS L+V SWV+FWL +A+ RV LG N L
Sbjct: 293 TLKREVGYYVMDYFLPSILLVCTSWVTFWLQADASAPRVTLGTSTMLAFITLNGGINKNL 352
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQKIASEKKL- 245
PK+SY+K+ +++ C +F S+ E+A V + K+++++++ I K A L
Sbjct: 353 PKVSYIKASEIWFLACACFIFCSMAEFAFVNVIWRRKKKVELKERSGKHILKGALTPSLA 412
Query: 246 -PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGR- 303
+ ++L K + + S S VH A K T+ N
Sbjct: 413 RKQLRKAESVNSLYKTQSCTSLNGSENGSKESHNNYLTVHSFPASMKVPTITTQSNDDLI 472
Query: 304 GGADEEN--PGPHPIHPGKDISKLLGMTPSD----IDKYSRIVFPVCFVCFNLMYW-IIY 356
GG D P P MTP + ID+ SRIVFP+ F+ FN+MYW +Y
Sbjct: 473 GGEDSVTTIPVPDTTRNKPQTQAWHTMTPHEVANWIDRKSRIVFPLGFLIFNIMYWTFVY 532
Query: 357 L 357
+
Sbjct: 533 I 533
>UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep:
CG7411-PA - Drosophila melanogaster (Fruit fly)
Length = 485
Score = 109 bits (263), Expect = 9e-23
Identities = 60/206 (29%), Positives = 100/206 (48%), Gaps = 4/206 (1%)
Query: 57 FRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS 116
F + H + + + ++ +T D+ ++W+ V V + LPQ ++ +
Sbjct: 159 FAIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLV-VDENIELPQVALIRNETADCTQV 217
Query: 117 LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXX 176
+TGN++ L R + YY+ YIP+ +IVI+SWVSFW+ A PARV LG
Sbjct: 218 YSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSLL 277
Query: 177 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAI 236
++LP +SY+K++D ++ C V VF +L+EY + + + K
Sbjct: 278 TLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYPP 337
Query: 237 QKIASE--KKLPE-CPPVGDPHTLSK 259
+ +A + KK E PP G T SK
Sbjct: 338 KPVAGDGPKKEGEGAPPGGSNSTASK 363
>UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 517
Score = 109 bits (262), Expect = 1e-22
Identities = 86/319 (26%), Positives = 137/319 (42%), Gaps = 26/319 (8%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGV-SSEVSLPQFKVLGHRQRAMEISLTTGNY 122
Q++ +TL + Y +++ +W + + E+ LP F + + G +
Sbjct: 202 QQSCHLTLESFSYNNQEVDMQWMNWTTPLSLLKKEIVLPDFVMSNYSTSLKHEIYPAGVW 261
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
+ L F R G+Y+ Q YIP+ L + ISW+SF L PAR LG
Sbjct: 262 NELTMTFVFSRRYGWYIFQAYIPTYLTIFISWISFCLGPKMIPARTMLGVNSLLALTFQF 321
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
LP++SYVK++DV++ C VF SLLE A +G M R + R+ A Q+ +
Sbjct: 322 GNIMRNLPRVSYVKALDVWMLVCLTFVFCSLLELAIIGSMGARSENRQ----AQQQKQQD 377
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCP--PSRPSKTISQEV--RFKVH---DPKAHSK---- 291
++ + + T S + + S CP P I +V FK + DP+ +
Sbjct: 378 EEATKHQKGRENSTCSHLMSPSSCPNSPRICRNHIPNDVPQSFKSYGSTDPRMRKRLIIA 437
Query: 292 -GGTLENTINGGRG-------GADEE--NPGPHPIHPGKDISKLLGMTPSDIDKYSRIVF 341
T+ + N R G +E + I T +ID+ S I+F
Sbjct: 438 SSSTISHAPNANRSEKVLLLDGLEETQFSQVETKFSSMASIKMKKHWTTEEIDRLSMIMF 497
Query: 342 PVCFVCFNLMYWIIYLHVS 360
P F FN++YW YL V+
Sbjct: 498 PGLFTLFNIIYWTYYLTVN 516
>UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 349
Score = 108 bits (260), Expect = 2e-22
Identities = 84/293 (28%), Positives = 141/293 (48%), Gaps = 37/293 (12%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAM--EISLTTGNYSRLA 126
+ L + Y+ ++I Y+W + P V V ++ +L QF + + + + EI GNYS L
Sbjct: 91 LKLGSYSYSTKNIVYRW-QSPLGVTVRNK-NLAQF-IFTYLELSEYEEIYGMMGNYSILQ 147
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ F R +GY+LIQ+Y P +V++SW+ FW++++ R+ALG N
Sbjct: 148 VDFAFKRRLGYFLIQVYAPDIFVVLLSWIVFWMDKDDMGNRMALGITTILTIMFLLGSVN 207
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLP 246
AA+P++SY K++D YL F +VF L+E V ++K R++R ++ +++ L
Sbjct: 208 AAMPRVSYPKALDWYLMVSFSLVFLVLIECMIVFVISKYKNDRRKRRIS-KRVPWLDSLR 266
Query: 247 ECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGA 306
+ G+ + K L P + HD L +IN G
Sbjct: 267 KRETNGNARAMEKSELLEMNPSVQ-------------HDESNVPTPPKLRLSINDLTGSH 313
Query: 307 DEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+ E +H D+ K ++RIVFP+ F+ FN++YW IYL V
Sbjct: 314 EGE------LH-DSDVDK-----------FARIVFPMVFIVFNILYWCIYLKV 348
>UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protein
1; n=6; Caenorhabditis|Rep: Expulsion defective
(Defecation) protein 1 - Caenorhabditis elegans
Length = 539
Score = 107 bits (257), Expect = 5e-22
Identities = 54/158 (34%), Positives = 83/158 (52%), Gaps = 3/158 (1%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQ 130
+ + GYT + YKW++G + ++ LP F + + S TGNYSRL
Sbjct: 249 IESYGYTADHVVYKWSKGARTALELKKIRLPDFTIQEAYVTSQMESYATGNYSRLYVCFV 308
Query: 131 FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALP 190
F RS G+ +Q+ IPS +VI SWVS W+ T N +P
Sbjct: 309 FSRSSGFCFLQLIIPSTAVVITSWVSLWME---TETEFQDMISIILAITFLIFSYNEMMP 365
Query: 191 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM 228
++SY+K++D+YLG CF++VF SL++ A V YM ++I +
Sbjct: 366 RVSYIKAMDIYLGVCFMIVFLSLIKLALVKYMRQKIML 403
>UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 106 bits (255), Expect = 8e-22
Identities = 56/139 (40%), Positives = 75/139 (53%), Gaps = 1/139 (0%)
Query: 84 KWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
KW G SV + ++LPQ VLG + R + +GNYSRL+ +F R + +L +
Sbjct: 152 KWKFGETGSVTWAENINLPQMDVLGVKGREVVDVFASGNYSRLSLAFKFKRRISLFLTET 211
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+P LIV +SWVSFW+N PARVAL +LPK++Y K D L
Sbjct: 212 YVPLVLIVALSWVSFWINYKVAPARVALCITTVLTIITLSASVRTSLPKVTYTKYSDWIL 271
Query: 203 GTCFVMVFASLLEYATVGY 221
T V VF +L+EYA V Y
Sbjct: 272 ITGLVYVFGALVEYAVVNY 290
>UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 434
Score = 106 bits (254), Expect = 1e-21
Identities = 50/161 (31%), Positives = 84/161 (52%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + Y D+ +W E V ++ +LP F++ ++ + T G + RL+
Sbjct: 197 LVFESYSYNAADVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTEAYTAGMWHRLSVS 256
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
I F R G+Y++Q+Y+P+ + V ISW++FW++ A PAR+ L +
Sbjct: 257 IHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMALTFQFGNIVKS 316
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
LPK SYVK+ID+++ +C +F SL+E A V Y K R
Sbjct: 317 LPKASYVKAIDIWMFSCVGFIFFSLIELAIVAYNDKMHDQR 357
Score = 35.1 bits (77), Expect = 3.0
Identities = 13/30 (43%), Positives = 19/30 (63%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVS 360
+ ID+ + ++FP F FNL+YW YL S
Sbjct: 399 ASIDRVASMLFPTMFALFNLVYWAYYLTTS 428
>UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-1 - Caenorhabditis elegans
Length = 466
Score = 105 bits (253), Expect = 1e-21
Identities = 53/156 (33%), Positives = 85/156 (54%), Gaps = 1/156 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+T + Y ++R +WN+ P V + + LP FK++ A+E G + L
Sbjct: 174 LTFESFNYNTGEVRMQWNQ-PYPVILLKRIELPDFKLVNFSVIAVEQMYPAGWWDELTVA 232
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R G+Y++Q YIP+ + ++ISW+SF+L A PAR LG
Sbjct: 233 FVFERRYGWYVLQGYIPTMVTIVISWISFYLGPRAIPARTMLGVNSLLAMTFQFGNIIRN 292
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LP++SYVK+IDV++ + + +F SLLE A VG+M++
Sbjct: 293 LPRVSYVKAIDVWMLSGMLFIFLSLLELAVVGFMSR 328
Score = 37.1 bits (82), Expect = 0.74
Identities = 13/30 (43%), Positives = 18/30 (60%)
Query: 328 MTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
+ P +D YS I FP ++ FN+ YW YL
Sbjct: 421 LRPETVDFYSAIFFPTAYMLFNISYWSFYL 450
>UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 105 bits (252), Expect = 2e-21
Identities = 54/153 (35%), Positives = 83/153 (54%), Gaps = 5/153 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+T+++ +T D+ Y WN+ G +L QF +LG + T+G YS L
Sbjct: 105 VTISSYFFTEDDLYYDWNDVSIYKG-----NLSQFDLLGLDSLRKSLVFTSGTYSSLVAT 159
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+F R + YL+ Y+P+ L V++SWVSF+++ N+ PAR ALG +
Sbjct: 160 FRFRRRIQNYLLSFYVPTILTVMLSWVSFFISPNSAPARCALGIITVLAVGGFLTNQRKS 219
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGY 221
P +SYV S D+Y+ C+V VF +LLEYA V +
Sbjct: 220 FPTVSYVMSADLYILVCYVFVFCALLEYAVVHF 252
>UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 262
Score = 105 bits (252), Expect = 2e-21
Identities = 56/166 (33%), Positives = 89/166 (53%), Gaps = 8/166 (4%)
Query: 69 ITLTTVGYTMRDIRYKWNEGP-----NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
I+ + G D+ W P N+V +S +++ QF + + + TG ++
Sbjct: 95 ISFESYGMNNDDLLLSWKADPGDKYKNAVIISDNLTMSQFALDEYHASKETFTYPTGTFT 154
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
L R YY++Q YIP+ LIVI+SWVSFW+ R++ PARVALG
Sbjct: 155 LLKLTFSIRRKKFYYVVQTYIPTILIVILSWVSFWIPRSSPPARVALGITTVLALTTLIF 214
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYAT---VGYMAKRI 226
+++P++SYVK+ID +L F+ VF +L+EY + + + AKRI
Sbjct: 215 GIQSSMPRVSYVKAIDWFLMVSFLFVFCALIEYPSSTFIKFQAKRI 260
>UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 201
Score = 105 bits (251), Expect = 2e-21
Identities = 55/156 (35%), Positives = 78/156 (50%), Gaps = 1/156 (0%)
Query: 119 TGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXX 178
TGN+S L +F R + YYL + YIP+ L V++SWVSFW++ ATPAR++L
Sbjct: 4 TGNFSALTVGFRFRREVYYYLFRFYIPASLTVVMSWVSFWISPLATPARISLTIITVLAM 63
Query: 179 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQK 238
+ PK SY +S DVY+ CFV VF L+EYA V Y+ + + K+ F +
Sbjct: 64 AGFLIGDHPDFPKSSYARSFDVYMMMCFVFVFGCLVEYAAVHYLLRDDKYNKKVFKHLND 123
Query: 239 IASEKKLPE-CPPVGDPHTLSKMNTLSRCPPSRPSK 273
I L + P T + +C P K
Sbjct: 124 INRNPNLNKIAPATQSAETALSTQSTDQCTNRDPPK 159
Score = 36.7 bits (81), Expect = 0.98
Identities = 12/23 (52%), Positives = 19/23 (82%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWII 355
+D+ SRI+FPV F+ FN +YW++
Sbjct: 179 LDEISRILFPVMFILFNTVYWVL 201
>UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4
precursor; n=2; Caenorhabditis|Rep: Glycine receptor
subunit beta-type 4 precursor - Caenorhabditis elegans
Length = 473
Score = 105 bits (251), Expect = 2e-21
Identities = 52/157 (33%), Positives = 80/157 (50%), Gaps = 1/157 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + Y + +WN G N V V+ + +P + + TG +S E
Sbjct: 182 LRILSYAYDEEQLIIRWNGG-NPVEVNRGIRMPDMHLKHIKFYTKRDKYATGIWSSAVAE 240
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R + +++IQ YIP+ LIVIISW SFWL+ A P RV+L A
Sbjct: 241 FHVDREITHHIIQSYIPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARMA 300
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
LP+ S VK+IDV++GTC VF++++E+ V Y +R
Sbjct: 301 LPQASDVKAIDVWMGTCMAFVFSAMIEFTVVNYCVRR 337
Score = 44.0 bits (99), Expect = 0.006
Identities = 17/37 (45%), Positives = 26/37 (70%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVANDLVL 369
ID+YSR +FP+ F+ FN+ YWI YL + + +L+L
Sbjct: 437 IDRYSRALFPLAFIIFNIFYWIYYLKYAGSNSPELLL 473
>UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 464
Score = 104 bits (249), Expect = 4e-21
Identities = 84/309 (27%), Positives = 148/309 (47%), Gaps = 41/309 (13%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKV------LGHRQ---RAME 114
Q+ T+I + Y ++ +WN+ S+ VS + +F V G + +
Sbjct: 174 QKCTLI-FSDWSYNSTNLLLEWNKKSESLNVSDNLHFTEFIVDEIKCDTGTNDGPYQNRD 232
Query: 115 ISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXX 174
+S G++S L + +F R +GYYL+ +IPS L+V +WV+FWL +A P R LG
Sbjct: 233 MSDQVGSFSELVIKFRFHRDIGYYLLDFFIPSYLLVCTAWVTFWLQADAGPPRATLGATT 292
Query: 175 XXXXXXXXXXXNAALPKISYVKSIDV-YLG-TCFVMVFASLLEYATVGYMAKR---IQMR 229
+ +PK+SY+K+ D+ +LG +CF +F SL E+A V + +R I+++
Sbjct: 293 VVAFITLHLGMSKDIPKVSYIKASDIWFLGVSCF--IFFSLAEFAFVNVIWRRKKIIELK 350
Query: 230 KQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAH 289
K + I K A P V H ++LS ++ + ++ D
Sbjct: 351 KPKQKYIIKAA------VMPSVARKHLRKHESSLSVATLTQSNSSL---------DVATP 395
Query: 290 SKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSD----IDKYSRIVFPVCF 345
+ G +N I+ + + + P+ + + MTP + ID+ +RIVFP+ F
Sbjct: 396 CENGCYKNGID-----SLDSSHSVIPMPEDEQVFTWTKMTPQEVAIWIDRKARIVFPLIF 450
Query: 346 VCFNLMYWI 354
+ FN++YW+
Sbjct: 451 LIFNILYWV 459
>UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep:
CG11340-PA - Drosophila melanogaster (Fruit fly)
Length = 526
Score = 103 bits (248), Expect = 6e-21
Identities = 83/307 (27%), Positives = 133/307 (43%), Gaps = 29/307 (9%)
Query: 70 TLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGH---------RQRAMEISLTTG 120
TL + Y ++ W E N V ++ L ++ ++G + M G
Sbjct: 224 TLESWMYNTTLVQLHW-ETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSLEG 282
Query: 121 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXX 180
NYS ++ + R +GYY+I ++PS +IV ISWVSFWL + TPAR LG
Sbjct: 283 NYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSFIT 342
Query: 181 XXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR---IQMRKQRFVAIQ 237
L K+SYV +V+ C + +F SL+E+A V + +R +Q++K+ I
Sbjct: 343 LSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTIWRRNNDLQLKKRTTKYIV 402
Query: 238 KIASEKKLPECPPVGDPHTLSKMNTLSRCPPSR---PSKTISQEVRFKVHDPKAHSKGGT 294
K L + G T S M+T+S + P+ T+ + P GG+
Sbjct: 403 KSTFVPHLKKHRRHGYRRTDSTMSTMSTTSMDKTCGPNNTV-----ITIETPII--IGGS 455
Query: 295 LENTINGGRGGADEENPGPHPIHPGKD--ISKLLGMTPSD----IDKYSRIVFPVCFVCF 348
L + +E K+ MTP + ID+ R VFP+ F+ F
Sbjct: 456 LSREDSAISLDEQDETSTSESSDSSKEKPAQTFATMTPKEVSLWIDRKMRFVFPLSFIVF 515
Query: 349 NLMYWII 355
N ++W +
Sbjct: 516 NALFWTL 522
>UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 194
Score = 103 bits (247), Expect = 8e-21
Identities = 70/222 (31%), Positives = 107/222 (48%), Gaps = 28/222 (12%)
Query: 142 IYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVY 201
IY+PS LIVI+SWVSFW++R T AR+A+G +LPK+SYVKS++++
Sbjct: 1 IYLPSYLIVILSWVSFWVDREQTAARIAMGITTVLTMATLIGSARVSLPKVSYVKSLELF 60
Query: 202 LGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
L CF+ VF+++LEY+ V Y+ R +++ + A Q I + L P G
Sbjct: 61 LIMCFLFVFSAILEYSFVSYLVFRQRVKNREDYAQQLIEPDDGLNPIDPDG--------- 111
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGKD 321
RP QE + P H L +G A P P+ D
Sbjct: 112 -----TDGRPRPEPGQEA---IWIPGKHQVEAVLTK-----KGVA----PTKKPLDKKND 154
Query: 322 ISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
+ +T ++ RI FP+ FV N+ YW+ YL ++++V
Sbjct: 155 NHYINLLT--KVEYIFRIAFPLTFVILNVFYWVYYLTIAELV 194
>UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 103 bits (247), Expect = 8e-21
Identities = 46/148 (31%), Positives = 80/148 (54%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
V+ + +T +I +W EG V +S +++LP F ++G + + +G ++ L
Sbjct: 123 VLQFESFFHTAAEIVLRWEEGDTPVAISKDMNLPHFDIVGLETKQIYNVYKSGKFNSLEV 182
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
I F R +GYYLIQ Y+P + +SW+ FW++ + T R+A+G N
Sbjct: 183 HITFRRRLGYYLIQTYLPCVFLCFLSWMPFWMDPSETGDRLAVGITAVLTIVFLAGAMNT 242
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLE 215
+PK+SY+K+ID Y+ CF+ + S +E
Sbjct: 243 NMPKVSYMKAIDWYVIACFLTMVLSFVE 270
>UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 443
Score = 103 bits (246), Expect = 1e-20
Identities = 80/284 (28%), Positives = 125/284 (44%), Gaps = 26/284 (9%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 135
+T DI ++WN PN + + L QF + G+ GNY+ + + R +
Sbjct: 172 FTDTDIFFRWNN-PNKLSRVQKSDLAQFHLAGYDLITETGIYEEGNYTTVKVIFKMNRRV 230
Query: 136 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYV 195
GYY+IQ Y P LIV++SW+ FW++ R+ALG NA++PK+SY
Sbjct: 231 GYYIIQAYCPDVLIVVLSWIIFWMDVKDMGDRMALGITTILTIMFLLGAVNASMPKVSYP 290
Query: 196 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGDPH 255
K++D YL F VF +L+E V + + + K + + +++ + PV
Sbjct: 291 KALDWYLMVSFAFVFLTLIESMIVFLLTPQGESEKPKKTS---CLTKRVVTMLTPV---- 343
Query: 256 TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENP--GP 313
L R P S T + + A L GGR G +
Sbjct: 344 -------LRRRPNSHVVTTPNNHELNNISPTDA----ALLNPEDGGGREGPNGTKACWDD 392
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
H H + SK G +D+ SR++FP+ FV +N+ YW YL
Sbjct: 393 HTGHVKE--SKCAGYR---VDQISRVLFPLAFVFYNVAYWYTYL 431
>UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 103 bits (246), Expect = 1e-20
Identities = 53/165 (32%), Positives = 91/165 (55%), Gaps = 3/165 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
I+ + GYT DI Y+W + V + + + QF + + TG++S L
Sbjct: 123 ISFASYGYTTADIVYQWAD--ERVTWAHDQEIAQFVLEKIETENLTRRYITGDFSALGIR 180
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG-XXXXXXXXXXXXXXNA 187
++ R +G+YL ++Y+P+ LIV++SW+SF+L+R++ PARV+LG
Sbjct: 181 LRLNRRLGHYLTRVYVPAVLIVMLSWLSFYLDRHSAPARVSLGITTVLTMTTLLIGIGQG 240
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
+LP +SYVK++D YL + MVF + EYA + + K ++ +R
Sbjct: 241 SLPVVSYVKALDWYLFVSYCMVFGAFAEYAVINHRDKSYFLKLRR 285
>UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 405
Score = 101 bits (243), Expect = 2e-20
Identities = 49/152 (32%), Positives = 84/152 (55%), Gaps = 2/152 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
+ + + +T+ D+ Y+W G V + SE + QF +LG R + + + G ++ L
Sbjct: 180 LRIESYAHTVADVDYRWKGGETQGVEIVSE-EMAQFDLLGVRTDTKKSTNSKGAFASLKA 238
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
+F R M +YL IY+P ++V++SW +F++ +A PAR AL N+
Sbjct: 239 TFRFRRRMDFYLSSIYVPEVILVVLSWTTFFITPSAVPARTALSITTILTTILLSSSVNS 298
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
+PK+SY+KSID ++ F +FA+L+EY V
Sbjct: 299 GMPKVSYMKSIDHFMLISFGFIFAALIEYIIV 330
>UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 508
Score = 101 bits (242), Expect = 3e-20
Identities = 80/305 (26%), Positives = 127/305 (41%), Gaps = 21/305 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVG-VSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLA 126
+T + Y +++ W+ N V + ++ L ++++ H+ R E G + L
Sbjct: 206 LTFESFNYNTDEVKMDWSV--NGVQKMRDKMELADYELVDIHKIRTTE-EYPAGYWHELT 262
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+F R G+Y++Q Y+P+ L + ISW+SF L A PAR LG
Sbjct: 263 MSFEFKRRAGWYILQAYLPTYLTICISWISFALGSKAIPARTMLGVNSLLAMTFQFGNII 322
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLP 246
LP++SYVK+IDV++ +C VF SLLE A VGY+++ + + +Q A P
Sbjct: 323 RNLPRVSYVKAIDVWMLSCMTFVFCSLLELAWVGYLSREEEPTSAK--CLQPSAQVAPKP 380
Query: 247 -ECPPVGDPHTLSKMNTLSRCPPS-RPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRG 304
PPV S ++ + P + S +S + P G + N +
Sbjct: 381 CHPPPVQQNANNSSVHRRQKQPKNEEESALLSLRDNDYGYIPPGFGLNGNVANAMKSFSS 440
Query: 305 GA------------DEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMY 352
DE P + + ID S +FP FV FN+ Y
Sbjct: 441 SCSCEPTNVVNLMLDEAETIPTSTSSSLSRKQRREILAHKIDSVSVFMFPFLFVLFNIAY 500
Query: 353 WIIYL 357
W YL
Sbjct: 501 WQHYL 505
>UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 494
Score = 101 bits (241), Expect = 4e-20
Identities = 52/192 (27%), Positives = 100/192 (52%), Gaps = 6/192 (3%)
Query: 39 WKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN--SVGVSS 96
W D S+ S + L ++ + + + + + Y M +R W+E + ++ +
Sbjct: 147 WYDARISIVSSCNMDLWKYPL---DSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNP 203
Query: 97 EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVS 156
++++P + R + TG +S + R M ++++Q Y+P+ LIV+ISW +
Sbjct: 204 DITMPDMSLKHIRTGYCNGTYATGEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFN 263
Query: 157 FWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEY 216
FWL ++ PARV+L ALP++SY+K+IDV++G+C VF ++E+
Sbjct: 264 FWLEIDSAPARVSLSITTLLTISTQANAVKLALPEVSYMKAIDVWMGSCMAFVFGVMIEF 323
Query: 217 ATVGYMAKRIQM 228
T+ + AK ++M
Sbjct: 324 -TICHYAKNLEM 334
Score = 35.9 bits (79), Expect = 1.7
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID+ RIVFP+ F+ FN+ YW YL
Sbjct: 467 IDERCRIVFPMIFLLFNVAYWSFYL 491
>UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 469
Score = 101 bits (241), Expect = 4e-20
Identities = 55/178 (30%), Positives = 89/178 (50%), Gaps = 4/178 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + Y + W P V V E+SL F + +R G + RL E
Sbjct: 171 LVFESYSYNTASVSVNWMANP--VTVLPEISLADFDLSRYRTSRHTEVYKAGEWYRLTVE 228
Query: 129 IQFVRSMGYYLIQI-YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
+F R G+Y++Q+ Y+P+ + + ISW++F ++ A PAR+ LG
Sbjct: 229 FEFTRKYGFYILQVLYVPTYISLFISWIAFCIDTKALPARIVLGVNSLMSLTFQFGNIIR 288
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRF-VAIQKIASEKK 244
+LP +SYVK+ID+++ TC +FASLLE A V Y K++ ++ + AI + S K
Sbjct: 289 SLPPVSYVKAIDLWMCTCVGFIFASLLELAFVAYQDKKLILKSGKSNAAISTLVSYLK 346
>UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p
- Drosophila melanogaster (Fruit fly)
Length = 612
Score = 100 bits (240), Expect = 5e-20
Identities = 50/156 (32%), Positives = 79/156 (50%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + GY + + Y+W ++V ++L QF ++ R G++S L
Sbjct: 249 LVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDLISMMHRNFTTVRREGDFSVLHVA 308
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY+LIQ+Y+P LIV++SWVSFW++R AT RV+L
Sbjct: 309 FNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVLTLSTISLDSRTD 368
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LPK+ Y ++D +L F+ A+LLE+A V Y K
Sbjct: 369 LPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTK 404
>UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 382
Score = 100 bits (239), Expect = 7e-20
Identities = 46/110 (41%), Positives = 65/110 (59%)
Query: 116 SLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXX 175
S G +S L ++ R++G++L+Q YIP+GLIV ISWVSFW++R A PARV+L
Sbjct: 182 SSRVGEFSCLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDRRAVPARVSLSFTTL 241
Query: 176 XXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
ALP +SY K+ID + G C + +F LLE+A V +R
Sbjct: 242 LTLSTQGNGIRYALPAVSYAKAIDYFYGVCMLFIFGVLLEFAAVNSYMRR 291
Score = 35.5 bits (78), Expect = 2.3
Identities = 13/25 (52%), Positives = 16/25 (64%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
IDK +R FP F FN+ YW+ YL
Sbjct: 351 IDKAARFAFPCVFAIFNVFYWLYYL 375
>UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 457
Score = 100 bits (239), Expect = 7e-20
Identities = 51/158 (32%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Query: 76 YTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
Y +++R +WNE V V++++ LP F+++ + G + L ++ F R
Sbjct: 204 YNNQEVRMRWNEKSAEPVSVTNKIRLPDFELIKIESTRISAPYPAGMWDELHVKLVFERR 263
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISY 194
+Y +Q Y+P+ L + ISW+SF L A PAR LG LP++SY
Sbjct: 264 YIWYFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNALLAMIFQFGNIMRNLPRVSY 323
Query: 195 VKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
VK+IDV++ +F SLLE A VGY K + K++
Sbjct: 324 VKAIDVWMLVSMTFIFLSLLELAIVGYKTKNEEGSKKK 361
Score = 41.1 bits (92), Expect = 0.046
Identities = 17/44 (38%), Positives = 26/44 (59%)
Query: 329 TPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVVANDLVLLEE 372
+P ID+ S I+FP CF FN++YW Y + A ++ L E+
Sbjct: 412 SPEKIDRVSAIMFPACFAIFNIVYWSYYYNKKLEKAAEMKLNED 455
>UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor
subunit beta-1 precursor (GABA(A) receptor subunit
beta-1).; n=1; Gallus gallus|Rep:
Gamma-aminobutyric-acid receptor subunit beta-1
precursor (GABA(A) receptor subunit beta-1). - Gallus
gallus
Length = 382
Score = 99 bits (238), Expect = 9e-20
Identities = 81/294 (27%), Positives = 128/294 (43%), Gaps = 22/294 (7%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
GYT DI + WN G ++V S + LPQF ++ ++ + + TG Y +L+ R+
Sbjct: 101 GYTTNDIEFYWNGGKSAVTGVSNIELPQFSIVDYKTVSKRVEFPTGTYPQLSLSFWLKRN 160
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX-NAALPKIS 193
GY+ +Q ++PS LI I+S VSFW+N +A+ ARVALG + L
Sbjct: 161 TGYFTLQTHMPSTLITILSRVSFWIN-DASAARVALGITTVLTMTTISTHLLSQMLGFFP 219
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
K + ++ ++ L+YA G K M K ++ I KL P G+
Sbjct: 220 QTKFKQITSTLPYIYIYLFKLDYAIKGSSCKDQSMNK-----VRHITEMSKLM-VEPQGN 273
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
LS +N R S +S R G GR
Sbjct: 274 M-LLSTLNI--RYDVSCSDVFLS--CRDAQGSMYTSDGAGLQHRRAPSGRALYTRSALDT 328
Query: 314 HPIHPGKDIS--------KLLGMTPSD-IDKYSRIVFPVCFVCFNLMYWIIYLH 358
H +H + K+ +T + IDK+SR+VF + F+ FN++YW+ ++H
Sbjct: 329 HRLHQKGHLQRRASQMRVKIPNLTDVNFIDKWSRMVFSITFILFNVVYWLYHVH 382
Score = 40.3 bits (90), Expect = 0.080
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 2/59 (3%)
Query: 26 YGVGYTMRDIRYHWKDGHSSV-GMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
Y GYT DI ++W G S+V G+SN ++LPQF ++ ++ + + T Y + +
Sbjct: 98 YSNGYTTNDIEFYWNGGKSAVTGVSN-IELPQFSIVDYKTVSKRVEFPTGTYPQLSLSF 155
>UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 299
Score = 99 bits (238), Expect = 9e-20
Identities = 51/141 (36%), Positives = 79/141 (56%), Gaps = 2/141 (1%)
Query: 76 YTMRDIRYKWNEGPNS-VGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
YT +DI+Y+W NS V V S +L QF + + GN +R+ F R
Sbjct: 160 YTTQDIKYRWRPPMNSSVDVRSR-NLAQFALTSIIEVEYVEHYDLGNQNRMCVCFTFQRR 218
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISY 194
+GY+LIQ+YIPS +V++SW+ FW++++ R+ALG NA++P++SY
Sbjct: 219 LGYFLIQVYIPSIFVVVLSWIVFWMDKDNMGDRMALGITTVLTIMFLLGAVNASMPRVSY 278
Query: 195 VKSIDVYLGTCFVMVFASLLE 215
K++D YL F +VF L+E
Sbjct: 279 PKALDWYLMVSFTLVFLVLIE 299
>UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr)
protein 2, isoform a; n=3; Caenorhabditis|Rep:
Gaba/glycine receptor family (See gbr) protein 2,
isoform a - Caenorhabditis elegans
Length = 546
Score = 99.1 bits (236), Expect = 2e-19
Identities = 45/157 (28%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + YT + KW E + + +++ ++ + + +TG +S + E
Sbjct: 172 LRILSYAYTTEQLVIKWKED-EPITRNPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAE 230
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R + ++++Q Y+P+ LIV+ISW SFWL+ A PARV+L A
Sbjct: 231 FFVKREITHHVMQSYVPTTLIVVISWFSFWLDVEAVPARVSLAITTLLTLSTQANAARMA 290
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
LP++SY+K+IDV++G C + VF ++E+ V Y ++
Sbjct: 291 LPEVSYMKAIDVWMGACMMFVFGVMIEFTIVNYAQRQ 327
Score = 39.5 bits (88), Expect = 0.14
Identities = 15/26 (57%), Positives = 20/26 (76%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
ID+ SR +FP+ F+ FNL YWI YL+
Sbjct: 518 IDQTSRWIFPLTFIIFNLTYWIYYLY 543
>UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14573, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 371
Score = 98.3 bits (234), Expect = 3e-19
Identities = 41/97 (42%), Positives = 65/97 (67%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
GYT DI + W G +V ++ LPQF ++ ++ + + +TG+Y RL+ + R+
Sbjct: 227 GYTTDDIEFYWRGGDGAVSGVDKIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFKLKRN 286
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG 171
+GY+++Q Y+PS LI I+SWVSFW+N +A+ ARVALG
Sbjct: 287 IGYFILQTYMPSILITILSWVSFWINYDASAARVALG 323
Score = 41.5 bits (93), Expect = 0.035
Identities = 16/60 (26%), Positives = 33/60 (55%)
Query: 25 NYGVGYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYK 84
N GYT DI ++W+ G +V ++++LPQF ++ ++ + + +T Y + +K
Sbjct: 223 NSADGYTTDDIEFYWRGGDGAVSGVDKIELPQFSIVDYKLISKNVVFSTGSYPRLSLSFK 282
>UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 391
Score = 98.3 bits (234), Expect = 3e-19
Identities = 53/163 (32%), Positives = 90/163 (55%), Gaps = 5/163 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGH--RQRAMEISLT-TGNYSRL 125
I + + Y + +R +W G +V V+ E+ L Q+ + + ++ L +GN+SRL
Sbjct: 132 IYIESFSYHKQKLRLRWGTG--AVTVNPELKLLQYDIGKPVVAEETVDYMLEKSGNFSRL 189
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+F R +G++LIQ + PS L+V++SW SFWL +A P RVAL
Sbjct: 190 VVFFRFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGL 249
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM 228
+ +P ++YVK++DV++ C + VFA+L E+ V + R Q+
Sbjct: 250 KSDIPPVAYVKALDVWMAGCMMFVFAALGEFVVVKVLDLRSQL 292
Score = 33.9 bits (74), Expect = 6.9
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID YSRI FP+ F+ F ++YW I L
Sbjct: 362 IDIYSRIGFPILFMLFIILYWPILL 386
>UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG02331 - Caenorhabditis
briggsae
Length = 472
Score = 97.5 bits (232), Expect = 5e-19
Identities = 55/208 (26%), Positives = 99/208 (47%), Gaps = 10/208 (4%)
Query: 69 ITLTTVGYTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
+ + Y + ++R W + P ++ + LP F+ T G + +L
Sbjct: 211 LVFESYSYNIAEVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKV 270
Query: 128 EIQFV----RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
F R GYY++Q+Y+P+ L V ISW++FW++ A PAR+ LG
Sbjct: 271 TFSFFFRFKRLYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQFG 330
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM-RKQRFVAIQKIASE 242
LP++S+VK+ID++ C +F SL+E A VG++ K ++ R+ R + Q+ +
Sbjct: 331 NIVKNLPRVSFVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRRSRRIKFQRAIAG 390
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSR 270
+ P+ + K + S+C +R
Sbjct: 391 GTIKNDRPM----SFRKYSCTSKCNSAR 414
>UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr)
protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine
receptor family (See gbr) protein 3 - Caenorhabditis
elegans
Length = 438
Score = 96.7 bits (230), Expect = 9e-19
Identities = 55/205 (26%), Positives = 98/205 (47%), Gaps = 11/205 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNE-GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
+ + Y + ++R W + P ++ + LP F+ T G + +L
Sbjct: 176 LVFESYSYNIAEVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTAGMWDQLKV 235
Query: 128 EI-----QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
+F R GYY++Q+Y+P+ L V ISW++FW++ A PAR+ LG
Sbjct: 236 TFSQTFYRFKRLYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALTFQF 295
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQM-RKQRFVAIQKIAS 241
LP++S+VK+ID++ C +F SL+E A VG++ K ++ R+ R + Q+ +
Sbjct: 296 GNIVKNLPRVSFVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRRSRRIKFQRAIA 355
Query: 242 EKKLPECPPVGDPHTLSKMNTLSRC 266
+ PV + K + S+C
Sbjct: 356 GGTIKNDRPV----SFRKYSCTSKC 376
>UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 435
Score = 95.5 bits (227), Expect = 2e-18
Identities = 50/152 (32%), Positives = 81/152 (53%), Gaps = 5/152 (3%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLAC 127
+ + Y + +W GP+ V V+ E+ L Q+ + L + I GN+SRL
Sbjct: 179 IESFSYDSEKLSLRW--GPDGVIVNPELKLLQYNLEDPLKIDESVSFIDEKNGNFSRLIV 236
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
QF R +G++LIQ + PS L+V++SW SFWL +A P RVAL +
Sbjct: 237 YFQFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSMLTLVTMFTGLKS 296
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
+P ++YVK++D+++ C VF++L E+ V
Sbjct: 297 DIPPVAYVKALDLWMAGCMFFVFSALGEFVVV 328
Score = 37.9 bits (84), Expect = 0.43
Identities = 14/21 (66%), Positives = 17/21 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYW 353
ID YSR+VFPV F+ F L+YW
Sbjct: 404 IDAYSRVVFPVLFLVFTLLYW 424
>UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 318
Score = 95.5 bits (227), Expect = 2e-18
Identities = 48/155 (30%), Positives = 77/155 (49%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 135
Y +D+ Y W S + + QF ++ ++ + +S L + F R
Sbjct: 149 YEQKDLNYTWRSKVGSDIAIYDKEMAQFDIIAAKRFLKHPVYHSPMFSGLTATMSFRRRS 208
Query: 136 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYV 195
YY+ Q+YIP +VI+SW++FW++ RV LG NA +P++SY+
Sbjct: 209 LYYIFQMYIPCTCVVILSWIAFWIDPKEGSERVGLGISAVLTISYMRGSMNAGMPRVSYL 268
Query: 196 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRK 230
KSID +L FV VF SL+EY V A++ + +K
Sbjct: 269 KSIDYFLLISFVFVFMSLIEYVLVLKDARKERRKK 303
>UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila
melanogaster|Rep: CG33989-PD, isoform D - Drosophila
melanogaster (Fruit fly)
Length = 737
Score = 95.1 bits (226), Expect = 3e-18
Identities = 43/156 (27%), Positives = 81/156 (51%)
Query: 70 TLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEI 129
++ ++ Y I+Y W +++ S ++ ++ ++ A + + GNYS L E+
Sbjct: 479 SMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLQVEL 538
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
F R YY ++IP ++V S+++FWL NA PARV +G + L
Sbjct: 539 TFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFRSTL 598
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
P +S + +++V+ G C ++ASLLE+ V Y+ ++
Sbjct: 599 PVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRK 634
>UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 510
Score = 95.1 bits (226), Expect = 3e-18
Identities = 47/127 (37%), Positives = 66/127 (51%)
Query: 98 VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSF 157
++L QF ++G R + G +S L R GY+LIQ+Y+P LIV++SWVSF
Sbjct: 207 MALSQFDLMGSPYRNLTFVRREGEFSVLQVSFNLQRHTGYFLIQVYVPCVLIVVLSWVSF 266
Query: 158 WLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYA 217
W++R AT RV LG LPK+ Y ++D +L F A+LLE+A
Sbjct: 267 WIHREATSDRVGLGITTVLTLSTISLDSRTDLPKVRYATALDWFLLMSFGYCIATLLEFA 326
Query: 218 TVGYMAK 224
V Y K
Sbjct: 327 GVHYFTK 333
Score = 37.5 bits (83), Expect = 0.56
Identities = 15/27 (55%), Positives = 19/27 (70%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYL 357
S IDK +RIVFP F N+ YW+IY+
Sbjct: 466 SYIDKVARIVFPASFGLLNICYWVIYV 492
>UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subunit
epsilon precursor (GABA(A) receptor subunit epsilon);
n=30; Eutheria|Rep: Gamma-aminobutyric acid receptor
subunit epsilon precursor (GABA(A) receptor subunit
epsilon) - Homo sapiens (Human)
Length = 506
Score = 95.1 bits (226), Expect = 3e-18
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Score = 41.1 bits (92), Expect = 0.046
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW++ L++
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLNL 506
>UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory
glycine receptor; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to inhibitory glycine
receptor - Strongylocentrotus purpuratus
Length = 431
Score = 94.7 bits (225), Expect = 4e-18
Identities = 51/165 (30%), Positives = 84/165 (50%), Gaps = 1/165 (0%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQ 130
L + G T D+ W S + LPQ+ + G G +S + +
Sbjct: 178 LQSFGLTTSDLVLLWGAQKLEFH-SHHMRLPQYYMTGVDFFDCTEQRYNGIFSCVRAQFT 236
Query: 131 FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALP 190
R++GYY++Q +IPS +V++SWV+FW++ A+PARV LG +P
Sbjct: 237 LERTLGYYMLQAFIPSIALVMVSWVTFWIDVRASPARVGLGVTIILSVISKTNGVRLDIP 296
Query: 191 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVA 235
+SY+K+IDV+ +C V +LLEYA V +++ + KQ+ +A
Sbjct: 297 PVSYLKAIDVWYTSCLFFVIGALLEYALVHHLSLGQKKTKQKVLA 341
>UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 286
Score = 93.9 bits (223), Expect = 6e-18
Identities = 48/145 (33%), Positives = 76/145 (52%), Gaps = 3/145 (2%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
G+T DI + G + +S EV + Q+ + R + TG +S I R
Sbjct: 131 GHTEDDIVIRCRGGKGLI-ISDEVEISQYSITEVTSRDFKGVYNTGVFSEPIATIVLKRR 189
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISY 194
+ YY+ Y+P+GL+V +SW+SFW++ + PARV+LG P +SY
Sbjct: 190 LMYYVYGYYLPAGLVVFLSWISFWIDPRSVPARVSLGVITILAMGSFLHGGKG--PSVSY 247
Query: 195 VKSIDVYLGTCFVMVFASLLEYATV 219
++DVY+ +C+V VF SLLE++ V
Sbjct: 248 ATALDVYIISCYVFVFTSLLEFSLV 272
>UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3).; n=2; Xenopus tropicalis|Rep:
Gamma-aminobutyric-acid receptor subunit alpha-3
precursor (GABA(A) receptor subunit alpha-3). - Xenopus
tropicalis
Length = 465
Score = 93.5 bits (222), Expect = 8e-18
Identities = 39/106 (36%), Positives = 59/106 (55%)
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
G Y + R +GY++IQ Y+P + VI+S VSFWLNR + PAR G
Sbjct: 233 GEYIVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMT 292
Query: 180 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
+LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 293 TLSISARNSLPKVAYATAMDWFMAVCYAFVFSALIEFATVNYFTKR 338
Score = 42.7 bits (96), Expect = 0.015
Identities = 18/28 (64%), Positives = 21/28 (75%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
S IDK SRIVFPV F FNL+YW Y++
Sbjct: 438 SRIDKISRIVFPVLFAIFNLVYWATYVN 465
>UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 2 isoform 2; n=2; Euteleostomi|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 2
isoform 2 - Macaca mulatta
Length = 403
Score = 92.7 bits (220), Expect = 1e-17
Identities = 38/104 (36%), Positives = 59/104 (56%)
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXX 181
Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR G
Sbjct: 189 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 248
Query: 182 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
+LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 249 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 292
Score = 42.3 bits (95), Expect = 0.020
Identities = 19/33 (57%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S ID+ SRIVFPV F FNL+YW YL+ V+
Sbjct: 367 SKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 399
>UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA -
Drosophila melanogaster (Fruit fly)
Length = 524
Score = 92.3 bits (219), Expect = 2e-17
Identities = 43/123 (34%), Positives = 69/123 (56%), Gaps = 5/123 (4%)
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
GNYS L+ + R +G+YL+ ++PS LIV ISWVSFWL + P R+ LG
Sbjct: 246 GNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTFI 305
Query: 180 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKI 239
LPK+SY+K +V+ C + +F S++E+A V + R+++ V ++K+
Sbjct: 306 TLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTI-----WRRKKSVPVKKL 360
Query: 240 ASE 242
S+
Sbjct: 361 NSK 363
>UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 290
Score = 91.9 bits (218), Expect = 2e-17
Identities = 45/124 (36%), Positives = 68/124 (54%), Gaps = 2/124 (1%)
Query: 96 SEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWV 155
S V LP+ + ++ ++ L GN+SR+ F R + Y L+QIY P+ LIV +SW+
Sbjct: 169 STVVLPRISI--YKSMSLNSVLFVGNWSRVTTTFLFKRQIEYALLQIYAPTMLIVSLSWL 226
Query: 156 SFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
SFW+++ A PARV LG PK+SY+K+ID + FV VF + +E
Sbjct: 227 SFWISKEAVPARVTLGVTTILTIVTLIGSFRFQFPKVSYIKAIDWFFIVSFVFVFGAQIE 286
Query: 216 YATV 219
+ V
Sbjct: 287 FIAV 290
>UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 428
Score = 91.1 bits (216), Expect = 4e-17
Identities = 50/158 (31%), Positives = 78/158 (49%), Gaps = 6/158 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+T + Y ++ +W + P + + + LP F + G +S L
Sbjct: 201 LTFESFNYNKDEVFMRWGDPP--LTIFKPIELPDFTMTNFSTSNKFQLYAAGYWSELNVN 258
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R G+YL+Q YIP+ + V ISW+ F+L A PAR +G
Sbjct: 259 FLFRRRSGWYLLQGYIPTYMTVFISWIPFYLGPKAIPARTMIGVNALLALTFQFGNIIRN 318
Query: 189 LPKISYVKSIDVYL--GTCFVMVFASLLEYATVGYMAK 224
LP++SY+K+IDV++ G CF VFASL E AT+G++ +
Sbjct: 319 LPRVSYIKAIDVWMLSGICF--VFASLFELATIGFLMR 354
Score = 35.5 bits (78), Expect = 2.3
Identities = 11/25 (44%), Positives = 18/25 (72%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
+D SR++FPV F +N +YW +Y+
Sbjct: 396 LDNTSRLMFPVVFTFYNFIYWFVYM 420
>UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4;
Caenorhabditis|Rep: Serotonin-gated chloride channel -
Caenorhabditis elegans
Length = 489
Score = 90.6 bits (215), Expect = 6e-17
Identities = 43/157 (27%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLAC 127
++ + + ++ W E +V + + LP F ++ + + + G + +L
Sbjct: 174 ILIFESYSHNSEEVELHWME--EAVTLMKPIQLPDFDMVHYSTKKETLLYPNGYWDQLQV 231
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
F R G+Y+IQ Y+P+ L +I+SWVSF + A PAR +G
Sbjct: 232 TFTFKRRYGFYIIQAYVPTYLTIIVSWVSFCMEPKALPARTTVGISSLLALTFQFGNILK 291
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
LP++SYVK++DV++ C VF +++E A V Y+++
Sbjct: 292 NLPRVSYVKAMDVWMLGCISFVFGTMVELAFVCYISR 328
Score = 38.3 bits (85), Expect = 0.32
Identities = 14/28 (50%), Positives = 19/28 (67%)
Query: 330 PSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
P +DK+S + FP+ F FNL+YW YL
Sbjct: 453 PEAVDKFSIVAFPLAFTMFNLVYWWHYL 480
>UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor
alpha-like precursor (GABA(A) receptor alpha-like and
glycine receptor-like subunit of Drosophila); n=3;
Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like
precursor (GABA(A) receptor alpha-like and glycine
receptor-like subunit of Drosophila) - Drosophila
melanogaster (Fruit fly)
Length = 686
Score = 89.8 bits (213), Expect = 1e-16
Identities = 47/130 (36%), Positives = 69/130 (53%), Gaps = 2/130 (1%)
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXX 181
YS L R MG +LIQ+Y P L+V++SWVSFWLNR AT RV+LG
Sbjct: 378 YSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 437
Query: 182 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIAS 241
LPK+SY ++D ++ F +FA++L++A V Y K + + I+++ S
Sbjct: 438 GLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTK--YGSGECYFIIEELDS 495
Query: 242 EKKLPECPPV 251
E E P+
Sbjct: 496 ESGESETEPL 505
Score = 38.3 bits (85), Expect = 0.32
Identities = 18/36 (50%), Positives = 24/36 (66%), Gaps = 1/36 (2%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYL-HVSDVVAN 365
S ID+ SRIVFP+ F+ N+ YW YL S ++AN
Sbjct: 645 SKIDRASRIVFPLLFILINVFYWYGYLSRSSRILAN 680
>UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p -
Drosophila melanogaster (Fruit fly)
Length = 449
Score = 89.0 bits (211), Expect = 2e-16
Identities = 56/202 (27%), Positives = 100/202 (49%), Gaps = 10/202 (4%)
Query: 81 IRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAME----ISLTTGNYSRLACEIQFVRSMG 136
++ +W++ + V ++ E+ L Q+ LG E + GN+SRL +F R +G
Sbjct: 191 VKLRWSD--SGVTLNPELKLLQYN-LGQPLELEESDGYMPEKVGNFSRLTVYFRFERQIG 247
Query: 137 YYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVK 196
++LIQ + PS L+V++SW SFWL +A P RV L A +P ++YVK
Sbjct: 248 HHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTL--LVTCMLTLVTMFTGADIPPVAYVK 305
Query: 197 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKI-ASEKKLPECPPVGDPH 255
++D+++ C + VFA+L E+ V + + Q + R + + S + +C V
Sbjct: 306 ALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNRIPKVLPMRISNMEKGQCATVASWE 365
Query: 256 TLSKMNTLSRCPPSRPSKTISQ 277
+ + + P+ P +T Q
Sbjct: 366 GGAVRSRKATQTPTTPGQTSLQ 387
Score = 35.5 bits (78), Expect = 2.3
Identities = 15/26 (57%), Positives = 18/26 (69%)
Query: 332 DIDKYSRIVFPVCFVCFNLMYWIIYL 357
+IDK SR VFP+ F F L+YW I L
Sbjct: 420 EIDKVSRAVFPILFFVFVLLYWPILL 445
>UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16;
Endopterygota|Rep: CG33989-PF, isoform F - Drosophila
melanogaster (Fruit fly)
Length = 779
Score = 89.0 bits (211), Expect = 2e-16
Identities = 40/156 (25%), Positives = 80/156 (51%)
Query: 70 TLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEI 129
++ ++ Y I+Y W +++ S ++ ++ ++ A + + GNYS L ++
Sbjct: 504 SMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYLIKNQTTACDQNSWRGNYSCLRVDL 563
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
F R +Y ++IP ++V S+++FWL NA PAR +G + L
Sbjct: 564 IFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTMLNFFTTSNGFRSTL 623
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
P +S + +++V+ G C ++ASLLE+ V Y+ ++
Sbjct: 624 PVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRK 659
>UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 273
Score = 87.8 bits (208), Expect = 4e-16
Identities = 41/134 (30%), Positives = 72/134 (53%), Gaps = 1/134 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L++ YT +I YKW G +V V ++ L QF + M + TG++ +
Sbjct: 141 LKLSSYSYTTENIIYKWKTGKPAVEVGTK-DLAQFDMKTVEISNMTDTFVTGDFEAIIVT 199
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R +GY++IQ++ P +V++SW+ FW++R R+ALG N++
Sbjct: 200 FTFKRRLGYFIIQVFAPDIFVVMLSWIVFWMDREDMGNRMALGITIILTIMFLLGAINSS 259
Query: 189 LPKISYVKSIDVYL 202
+P++SY K++D YL
Sbjct: 260 MPRVSYPKALDWYL 273
>UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like
protein T20B12.9; n=2; Caenorhabditis|Rep:
Uncharacterized glycine receptor-like protein T20B12.9 -
Caenorhabditis elegans
Length = 476
Score = 87.4 bits (207), Expect = 5e-16
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
I L + + ++R W++ P + + +V LP F ++G + G + R +
Sbjct: 158 IVLESYSFNTDEVRLMWHDVP--ITMMEKVELPDFDLIGWSTDHQRLEYPNGIWDRAKVK 215
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R G+YL Q Y P+ L VI SWV F+ + + AR+ LG
Sbjct: 216 FTFARRYGFYLFQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQFGNVLRH 275
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
LP++SY+K +DV++ + +F +L+E A V
Sbjct: 276 LPRVSYIKCLDVWMIFSVIFIFCTLVELAIV 306
Score = 36.7 bits (81), Expect = 0.98
Identities = 14/34 (41%), Positives = 22/34 (64%)
Query: 328 MTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHVSD 361
+T +D+ S I+FP+ F+ FN++YW IY D
Sbjct: 440 ITSVQVDRCSMIMFPLSFLIFNVVYWSIYFMKMD 473
>UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4;
n=2; Apocrita|Rep: PH-sensitive chloride channel variant
4 - Apis mellifera (Honeybee)
Length = 489
Score = 87.0 bits (206), Expect = 7e-16
Identities = 43/150 (28%), Positives = 77/150 (51%), Gaps = 1/150 (0%)
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
GNYS L ++ F R +Y ++IP ++V S+++FWL NA PARV +G
Sbjct: 285 GNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFF 344
Query: 180 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKI 239
+ LP +S + +++V+ G C ++ASLLE+ V Y+ ++ M + +
Sbjct: 345 TTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPMHNVVYRPGENP 404
Query: 240 ASEKKLPECPPVGDPHTLSKMNTLSRCPPS 269
++K+ PP G +++ T + C P+
Sbjct: 405 VTQKR-EGGPPTGATTGPNEIVTCTNCGPN 433
>UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 563
Score = 87.0 bits (206), Expect = 7e-16
Identities = 52/186 (27%), Positives = 94/186 (50%), Gaps = 7/186 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNS--VGVSSEVSLPQFKVLGHR--QRAMEISLTTGN--Y 122
+T+ + Y + + W + P + +G + ++ L ++ R + A + G +
Sbjct: 264 LTIQSFAYIEQIVNLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKCAGPYPMFRGEAAW 323
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
S + I R + +++IQ YIP+G++V ISW+SFWL+ A+PAR++L
Sbjct: 324 SCIQGYIVMKRLVLFHIIQTYIPTGMLVSISWMSFWLDPRASPARISLTITSLLTLTTMS 383
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG-YMAKRIQMRKQRFVAIQKIAS 241
LP++SY+K++D++L ++F LLEY+ V YM KR R + ++
Sbjct: 384 NGARQDLPQVSYIKALDIWLTFSQALIFLVLLEYSFVSYYMTKRTTDCSHRNMFYEERVQ 443
Query: 242 EKKLPE 247
E K E
Sbjct: 444 ECKREE 449
>UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 428
Score = 86.2 bits (204), Expect = 1e-15
Identities = 53/173 (30%), Positives = 85/173 (49%), Gaps = 6/173 (3%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVS----LPQFKVLGHRQRAMEISLTT 119
Q+ + L + GY I Y W EG + G+ + +PQ+ ++
Sbjct: 169 QQNCPLVLESYGYDRSHIVYHW-EGNATDGLPFVPNRMRIMPQYSLVRLTLSREWHQYII 227
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
GN+S + RS Y+L +Y S +IV ISW+ F + + T AR+A+G
Sbjct: 228 GNFSAVVAVFSIERSYTYFLTHVYGTSCVIVFISWMGFVIPPDQTAARIAVGVTTLLTQV 287
Query: 180 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM-AKRIQMRKQ 231
N+++PK+SYVKSID +L +C + VF SL+EY + + KR + +Q
Sbjct: 288 TVINILNSSMPKVSYVKSIDKFLISCLIFVFLSLIEYCVILILDGKRTRRHQQ 340
>UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to
gamma-aminobutyric acid receptor rho1 subunit; n=1; Bos
taurus|Rep: PREDICTED: similar to gamma-aminobutyric
acid receptor rho1 subunit - Bos taurus
Length = 299
Score = 85.4 bits (202), Expect = 2e-15
Identities = 37/79 (46%), Positives = 51/79 (64%), Gaps = 1/79 (1%)
Query: 154 WVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASL 213
WVSFW++R A PARV LG NA++P++SY+K++D+YL FV VF S+
Sbjct: 120 WVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSV 179
Query: 214 LEYATVGYMAKRIQMRKQR 232
LEYA V Y+ +Q RK+R
Sbjct: 180 LEYAAVNYLT-TVQERKER 197
Score = 42.7 bits (96), Expect = 0.015
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSRI+FP ++ FNL+YW I+
Sbjct: 275 IDKYSRIIFPAAYILFNLIYWSIF 298
>UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-4 - Caenorhabditis elegans
Length = 408
Score = 82.2 bits (194), Expect = 2e-14
Identities = 44/132 (33%), Positives = 70/132 (53%), Gaps = 2/132 (1%)
Query: 94 VSSEVSLPQFKVLGHRQRAMEISL-TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVII 152
+ ++LP + VL + E+ L G ++ L F R G+Y++Q+Y+P+ + V I
Sbjct: 220 LKGNITLPDY-VLVDFSSSSELRLYPPGIFNELIATFTFQRLYGFYILQVYVPAYISVFI 278
Query: 153 SWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFAS 212
SWVSF L P+R +G LPK S VK+IDV++ + +FAS
Sbjct: 279 SWVSFTLGAEQIPSRTTVGVNSLLALTFQFGAVVNNLPKTSDVKAIDVWILSSMAFIFAS 338
Query: 213 LLEYATVGYMAK 224
L+E A VGY+++
Sbjct: 339 LIELAVVGYLSR 350
Score = 39.1 bits (87), Expect = 0.18
Identities = 16/29 (55%), Positives = 20/29 (68%)
Query: 329 TPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
T ID+ S IVFPV F+ FN+ YW I+L
Sbjct: 372 TALKIDQMSSIVFPVSFLAFNIWYWFIFL 400
>UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 400
Score = 82.2 bits (194), Expect = 2e-14
Identities = 43/164 (26%), Positives = 78/164 (47%), Gaps = 3/164 (1%)
Query: 76 YTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM 135
Y ++R +WN + V E+ + F + ++ G + L F R
Sbjct: 221 YNNEEVRLQWNSQRSPVFALQEIRIADFWLKDITPAVIKRDYPAGLWDELVVTFVFERRY 280
Query: 136 GYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYV 195
+Y +Q Y+P+ + ISW++F L A R +G LP++SY+
Sbjct: 281 MWYFLQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGSIMKNLPRVSYI 340
Query: 196 KSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKI 239
K+IDV++ + VF SL+E A VGY ++Q+++++ I+K+
Sbjct: 341 KAIDVWMLSSMTFVFLSLIELAIVGY---KLQIQREKEHVIEKV 381
>UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 618
Score = 82.2 bits (194), Expect = 2e-14
Identities = 41/172 (23%), Positives = 80/172 (46%), Gaps = 4/172 (2%)
Query: 62 HRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTG 120
H A + ++++G+T ++ +W N ++ + V +P+ + +G
Sbjct: 383 HDNPAVSLKISSMGFTQDVVKLEWFSDTNDAIWIEKNVKIPELSIRHLHPDTCNGVRKSG 442
Query: 121 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXX 180
YS L + R +GY++ YIP+ + V+ SW+S WL R+ +
Sbjct: 443 VYSCLEAKFYMHREVGYHIANTYIPTAICVVFSWISVWLPEEFVEGRIFVSLTVFLTLSA 502
Query: 181 XXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV---GYMAKRIQMR 229
LPK+SYVK+ID++ G VF ++L+ V + +KR++++
Sbjct: 503 ENNSAKEELPKVSYVKAIDIWFGFTSTFVFLTMLQALVVISLEHNSKRLRLK 554
>UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.16;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T15B7.16 - Caenorhabditis elegans
Length = 435
Score = 82.2 bits (194), Expect = 2e-14
Identities = 39/115 (33%), Positives = 64/115 (55%)
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
+L + F R+ G+Y++Q+YIP+ V +S+VSFW++ A PAR+ LG
Sbjct: 247 QLTVSLTFSRAYGFYILQMYIPTYSSVFLSFVSFWIDLKALPARITLGVSSLMALTFQYG 306
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQK 238
LP++ YVKSIDVY+ +F +++E A V Y+ +R++ A +K
Sbjct: 307 NVAKNLPRVGYVKSIDVYMVLTTAFIFLTMIEVAFVCYLDSENNLRRKERQAEKK 361
>UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor
subunit rho-1 precursor (GABA(A) receptor subunit
rho-1).; n=1; Takifugu rubripes|Rep:
Gamma-aminobutyric-acid receptor subunit rho-1 precursor
(GABA(A) receptor subunit rho-1). - Takifugu rubripes
Length = 477
Score = 81.8 bits (193), Expect = 3e-14
Identities = 38/104 (36%), Positives = 59/104 (56%), Gaps = 1/104 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ + +SL QF + H + +TG Y+RL
Sbjct: 197 LELESYAYTDEDLMLYWKSGDESLSIDDRISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 256
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG 171
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG
Sbjct: 257 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLG 300
Score = 40.7 bits (91), Expect = 0.060
Identities = 14/24 (58%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSR++FP ++ FNL+YW +Y
Sbjct: 453 IDKYSRMIFPGSYIFFNLIYWSVY 476
>UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF15015, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 201
Score = 80.6 bits (190), Expect = 6e-14
Identities = 33/88 (37%), Positives = 53/88 (60%), Gaps = 1/88 (1%)
Query: 141 QIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS-YVKSID 199
+ Y+PS L+V++SWVSFW+++++ PAR +G +LP + ++K+ID
Sbjct: 2 ETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAID 61
Query: 200 VYLGTCFVMVFASLLEYATVGYMAKRIQ 227
VYLG CF +F +LLEYA + + Q
Sbjct: 62 VYLGICFTFIFGALLEYACAHFYTMQHQ 89
>UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 536
Score = 80.2 bits (189), Expect = 8e-14
Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 4/165 (2%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVS----SEVSLPQFKVLGHRQRAMEISLTT 119
++A + + + Y+ +++YKW + GV S LPQF + G +
Sbjct: 201 KQACRLVIGSYAYSSDEVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPANITRD 260
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
YS L F R GY+L+ Y+P L+V++ WV+F+ R AT R+ +G
Sbjct: 261 KEYSALEVRFYFDRHFGYFLMNFYVPCALVVLLCWVAFFTKREATAERIGIGITNVLTIV 320
Query: 180 XXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
+ PK+ +++V++ C++ ++E+ V Y K
Sbjct: 321 LISMDSKSDSPKVDSPTALEVFIWICYLTHLICMVEFTVVHYHTK 365
>UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG06736 - Caenorhabditis
briggsae
Length = 394
Score = 79.8 bits (188), Expect = 1e-13
Identities = 47/180 (26%), Positives = 74/180 (41%), Gaps = 1/180 (0%)
Query: 57 FRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS 116
FR+ + Y ++R +WN V + L F + +
Sbjct: 196 FRLTKQMMLKNSLFFLNFSYNNEEVRLQWNSQRKPVFAIQPIRLADFTLKDITTGTISRD 255
Query: 117 LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXX 176
G + L F R +Y +Q Y+P+ + ISW++F L A R +G
Sbjct: 256 YPAGKWDELIVTFVFERRYMWYFLQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALL 315
Query: 177 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAI 236
LPK+SY+K+IDV++ + VF SL+E A VGY +R + K+ V I
Sbjct: 316 SMIFHFGSIMKNLPKVSYIKAIDVWMLGSMLFVFLSLVELAVVGYTLQR-RRGKEHIVEI 374
>UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 93
Score = 79.0 bits (186), Expect = 2e-13
Identities = 33/93 (35%), Positives = 53/93 (56%)
Query: 117 LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXX 176
+ +G + + F R++GY L+Q+Y P+ LIV +SW++FW+ R+A PAR+ L
Sbjct: 1 IVSGAWIHITASFVFNRNIGYSLLQVYAPTTLIVALSWLAFWIPRDAVPARITLSVTTIL 60
Query: 177 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 209
PK+SYVK++DV+L F+ V
Sbjct: 61 TIVTLMGSFRTQFPKVSYVKAVDVFLIVSFLFV 93
>UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 502
Score = 73.7 bits (173), Expect = 7e-12
Identities = 36/126 (28%), Positives = 68/126 (53%), Gaps = 2/126 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRA-MEISLTTGNYSRLAC 127
+ L + Y D+ W G +S+ + E+ L QF + + + + +TG Y+RL
Sbjct: 201 LELESYAYNENDLMLYWKNGNDSLR-TDEIVLSQFFIEQFQASSGLAFYSSTGWYNRLFI 259
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++++Q Y P+ L+V++SWVSFW++R A PARV+LG ++
Sbjct: 260 SFLLRRHIFFFMLQTYFPTMLMVVLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVSS 319
Query: 188 ALPKIS 193
++P+++
Sbjct: 320 SMPQVT 325
Score = 50.0 bits (114), Expect = 1e-04
Identities = 20/42 (47%), Positives = 31/42 (73%)
Query: 191 KISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
++SYVK++D+YL T F++VF S++EYA V Y +MRK +
Sbjct: 358 QVSYVKAVDIYLWTSFLLVFLSVIEYAAVNYCTTLEEMRKMK 399
Score = 37.9 bits (84), Expect = 0.43
Identities = 13/24 (54%), Positives = 19/24 (79%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
ID YSR+VFP+ ++ FN +YW +Y
Sbjct: 478 IDSYSRVVFPLSYLLFNTIYWGLY 501
>UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 7
SCAF8790, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 66
Score = 70.5 bits (165), Expect = 7e-11
Identities = 29/54 (53%), Positives = 43/54 (79%)
Query: 118 TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG 171
+TG+Y RL+ + R++GY+++Q Y+PS LI I+SWVSFW+N +A+ ARVALG
Sbjct: 1 STGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 54
>UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 239
Score = 69.7 bits (163), Expect = 1e-10
Identities = 34/119 (28%), Positives = 58/119 (48%), Gaps = 3/119 (2%)
Query: 75 GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRS 134
GYT DI+ W + ++++ + QF + + + GNY+ L+ R
Sbjct: 124 GYTDNDIKLSWKS--TKILIANK-EMAQFSLGDCVLSSKTMEYVQGNYTLLSASFPMHRR 180
Query: 135 MGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GYY IQ+Y+P +V++SW+ FW+N T R+ +G N+ LPK+S
Sbjct: 181 IGYYAIQMYVPCTFLVMLSWIVFWMNPEETGNRLTVGITTILTIVFLLGYTNSTLPKVS 239
>UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 409
Score = 68.1 bits (159), Expect = 3e-10
Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 2/126 (1%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + YT + + W +G N + + ++ L +F + ++++ G Y L
Sbjct: 180 LVFESFAYTNDHVAFHW-KGRNPITIFNK-ELSEFDMEQWLIEEVDMTYVAGKYRNLKVT 237
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
F R +G+YLI Y+P ++VI+SW+ FW++ ++ R++LG N+
Sbjct: 238 FIFRRRLGFYLINFYVPCVVMVIMSWIVFWMDSSSIGERISLGITTILTIVFLLGSSNST 297
Query: 189 LPKISY 194
+P++SY
Sbjct: 298 MPRVSY 303
>UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Rep:
GABA-A receptor - Caenorhabditis remanei
Length = 206
Score = 66.5 bits (155), Expect = 1e-09
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Query: 97 EVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVS 156
+V LP+ + + +G +S L + R +G+++ Q YIP+ L ++ SWV
Sbjct: 6 DVKLPELYIDRYETTTCANERKSGAFSCLRAVFRLKRDVGFHIAQTYIPTSLALMFSWVG 65
Query: 157 FWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE- 215
WL R+ + LP +SY+K+ID++ G VF +LL+
Sbjct: 66 VWLPEEFMEGRIGVAITVLLTLSTESAGAREHLPSVSYLKAIDLWFGFITGFVFFTLLQT 125
Query: 216 YATVGYMAKRIQMRK 230
+G+ + Q++K
Sbjct: 126 LFVIGFDKRANQLKK 140
>UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1;
Aedes aegypti|Rep: Glycine receptor beta, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 439
Score = 66.1 bits (154), Expect = 1e-09
Identities = 70/312 (22%), Positives = 127/312 (40%), Gaps = 28/312 (8%)
Query: 69 ITLTTVGYTMRDIRYKWNEG-----PNSVGVSSEVSLPQFKVLGH-RQRAMEISLTTGNY 122
+ ++ Y++R++R++W P G LP++ V + Q I N+
Sbjct: 132 VDFSSYKYSVREMRFRWKNDNGLIFPKDFG-DGFFRLPKYVVSFYTEQNPQTIHYGEDNH 190
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
S EI R + YL++ Y+PS L V +SW SF + P R+ L
Sbjct: 191 SSARLEITLSREVKSYLLENYLPSTLFVSMSWGSFVVVPEIVPGRMVLLVTTLLSLITMF 250
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
P +K ++V+L +C + VF +L+EY V + R+ ++
Sbjct: 251 DTVRNNSPDALELKCLEVWLISCTLFVFFALMEYFIVLFGI--------RYDKHWRVPKA 302
Query: 243 KKLPECPPVGDPHTLS-KMNTL-----SRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLE 296
+ PPV TLS NT+ SR P R + S ++ + + +
Sbjct: 303 HHVQVAPPVQIQSTLSLSPNTVETPMNSRHAPQRENGLESTGLKVTGTNKVQPQEADASK 362
Query: 297 NTINGGRGGADEENPGPHPIHPGK------DISKL-LGMTPSDIDKYSRIVFPVCFVCFN 349
+ G G+ + + + D++ + G +D+ S I+FP+ F+ F
Sbjct: 363 VSSIGNLSGSFQTTQHVTSVMTRRRFRNVADVALMYAGSQRGRLDQISLIIFPLSFLIFT 422
Query: 350 LMYWIIYLHVSD 361
+ YW +Y+ S+
Sbjct: 423 IAYWTMYISESN 434
>UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1;
Danio rerio|Rep: glycine receptor, beta b - Danio rerio
Length = 451
Score = 60.9 bits (141), Expect = 5e-08
Identities = 51/185 (27%), Positives = 84/185 (45%), Gaps = 25/185 (13%)
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQ-MRKQRFVAIQKIASEKKLPE 247
LPK+SYVK+ID++L C + FASL+EYA V M + + +R K +E K P
Sbjct: 276 LPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVMLNSPKLLEAERAKIATKEKAEGKTPA 335
Query: 248 CPPVGDP-----HTLSKMNTLSRCPPSRPSKT---------ISQEVR-FKVHDPKAHSKG 292
+ H + T +RC SK+ + R F++ + + K
Sbjct: 336 KNTINGMGSTPIHVSTLQVTETRCKKVCTSKSDLRTNDFSIVGSLPRDFELSNFDCYGKP 395
Query: 293 GTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMY 352
+ + + + +++ P P P+ P ID Y+R +FP F+ FN++Y
Sbjct: 396 IEVGSAFSKSQAKNNKKPPPPKPVIPS---------AAKRIDLYARALFPFSFLFFNVIY 446
Query: 353 WIIYL 357
W +YL
Sbjct: 447 WSVYL 451
>UniRef50_Q7M3M7 Cluster: Gamma-aminobutyric acid A receptor; n=1;
Drosophila sp.|Rep: Gamma-aminobutyric acid A receptor -
Drosophila sp. (Fruit fly)
Length = 210
Score = 60.5 bits (140), Expect = 7e-08
Identities = 63/172 (36%), Positives = 79/172 (45%), Gaps = 53/172 (30%)
Query: 18 YDKRVRPNYG-----VGYTMRDIR------------YHWKDGHSSVGMSNEVQLPQFRVL 60
YDKRVRPNYG VG TM I ++++ H S ++ ++L
Sbjct: 22 YDKRVRPNYGGPPVEVGVTMYSISSVSEVLMDFTLDFYFRQFHHSGSITRSIRLTITASC 81
Query: 61 GHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTG 120
++ I + + GYTMRDIRY QRA EI+LTTG
Sbjct: 82 PMNRQLCHIEIESFGYTMRDIRYF-------------------------QRATEINLTTG 116
Query: 121 NYSRLACEIQ-FVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALG 171
NYSRLACEIQ FV M + + Y G + RNATPARVALG
Sbjct: 117 NYSRLACEIQCFV--MVFASLLEYATVGYMA--------KRRNATPARVALG 158
Score = 47.2 bits (107), Expect = 7e-04
Identities = 21/21 (100%), Positives = 21/21 (100%)
Query: 205 CFVMVFASLLEYATVGYMAKR 225
CFVMVFASLLEYATVGYMAKR
Sbjct: 127 CFVMVFASLLEYATVGYMAKR 147
>UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel
ligand-binding; n=2; Chroococcales|Rep:
Neurotransmitter-gated ion-channel ligand-binding -
Crocosphaera watsonii
Length = 340
Score = 56.8 bits (131), Expect = 9e-07
Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 4/152 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG--HRQRAMEISLTTGNYSRLA 126
I L + Y+ +I + E N G+SSE+SL + ++G A + +Y+R
Sbjct: 151 IELISFSYSPEEIHFVEAEELN--GISSEISLVNWSIIGLSSHSHAHYLQPEQQDYARFD 208
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
EI+ R +Y ++ P LIV +S + FWL ++ L
Sbjct: 209 YEIKVKRHSSFYAWRVLFPVALIVFMSDLVFWLEPTQIIPQITLATATMVSLITYQFILR 268
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYAT 218
LPK++Y+ + D + ++VF +L++ T
Sbjct: 269 QELPKMNYLTAEDKVIVGSMLLVFIALVKSVT 300
>UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit
precursor; n=3; Chromadorea|Rep: Ligand-gated chloride
channel subunit precursor - Dirofilaria immitis (Canine
heartworm)
Length = 406
Score = 53.2 bits (122), Expect = 1e-05
Identities = 40/159 (25%), Positives = 69/159 (43%), Gaps = 5/159 (3%)
Query: 65 RATVITLTTVGYTMRDIRYKWNEGPNSV---GVSSEVSLPQFKVLGHRQRAMEISLTTGN 121
R + L++ Y + DI Y W P +V VS E+ ++ + T G
Sbjct: 176 RMIKLRLSSYKYPIEDIVYLWANSPPTVIPVEVSQELLTGFYEFKEAVAEDCAGNYTIGI 235
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRN-ATPARVALGXXXXXXXXX 180
YS + I F + +I+IPS L++++SW+ FW++ + + P ++
Sbjct: 236 YSCIDVLITFTGASSEAFWRIFIPSILLILVSWLHFWVHGSWSVPRTISAAVPFLIFVSI 295
Query: 181 XXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATV 219
L V S+ ++L C + FASL+EY V
Sbjct: 296 LIFYPQPNLTTYG-VSSLQIWLFFCLIFTFASLVEYFIV 333
>UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1;
Roseobacter sp. AzwK-3b|Rep: Putative uncharacterized
protein - Roseobacter sp. AzwK-3b
Length = 244
Score = 51.6 bits (118), Expect = 3e-05
Identities = 27/98 (27%), Positives = 42/98 (42%)
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
S L I R + YYL +I +P +V +SWV FW+ N ++ LG
Sbjct: 108 SMLTLTISADREVNYYLFRIMLPLFFVVAMSWVIFWVPPNRFEFQIGLGATSMLTVIAFN 167
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVG 220
+LP + Y+ +D L +VF ++ E G
Sbjct: 168 LAVAGSLPPLGYLTVLDQILIWSIAIVFLAIAEALVTG 205
>UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1;
Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
protein - Lyngbya sp. PCC 8106
Length = 343
Score = 50.0 bits (114), Expect = 1e-04
Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Query: 93 GVSSEVSLPQFKV---LGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLI 149
G++ E+SLP + + H + I+ ++ E++ R YY+ ++ +P LI
Sbjct: 178 GLAEEISLPNWSTNIPVAHNG-SRHIAQLNQSFVCFDYELKVKRYTAYYITRVILPLILI 236
Query: 150 VIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMV 209
V++S+ FW +V + +LP++ Y+ +D ++ V+V
Sbjct: 237 VLMSYAVFWFPPGQIMPQVTISVTAILSLITYEFTLQQSLPQVPYLTVLDKFVIGAMVLV 296
Query: 210 FASLLEYATVGYMAK 224
F +L+E T +A+
Sbjct: 297 FLALVETVTTIELAE 311
>UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 679
Score = 45.6 bits (103), Expect = 0.002
Identities = 33/169 (19%), Positives = 70/169 (41%), Gaps = 4/169 (2%)
Query: 57 FRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS 116
F + H ++ + ++++ Y+ + +++ W+ P + S+++LP+ + +
Sbjct: 448 FCLYPHDRQECDLRISSIAYSNQYVKFHWHSNP--IKFQSKITLPELHITKIKTAECSTK 505
Query: 117 LTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXX 176
+ S L R ++I+ Y+PS L ++ +WV+ ++ N R+
Sbjct: 506 GKLVDASCLRIIFSLERDSARFVIEKYVPSTLAMMFAWVAPYVPYNYEDVRIITPITVLL 565
Query: 177 XXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
+ SY+ SIDV+ SLLE V + KR
Sbjct: 566 TLVQMEKGDKEI--RTSYLTSIDVWFAAMKSFTVLSLLESLAVLALIKR 612
>UniRef50_Q9WV58 Cluster: Gamma-aminobutyric acid A receptor gamma 1
subunit; n=1; Mus musculus|Rep: Gamma-aminobutyric acid
A receptor gamma 1 subunit - Mus musculus (Mouse)
Length = 119
Score = 42.3 bits (95), Expect = 0.020
Identities = 16/27 (59%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
ID YSRI FP F FNL+YW+ YL++
Sbjct: 93 IDSYSRIFFPTAFALFNLVYWVGYLYL 119
>UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 394
Score = 41.9 bits (94), Expect = 0.026
Identities = 23/93 (24%), Positives = 37/93 (39%)
Query: 122 YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXX 181
+S + R GYYL +I IP +IV +W +FW+ R+
Sbjct: 257 FSEYVYSVNVDRDPGYYLYKIVIPLLIIVAFNWATFWMPGEPASVRMERTVIALLTVVAF 316
Query: 182 XXXXNAALPKISYVKSIDVYLGTCFVMVFASLL 214
LP+I Y+ +D + F V ++L
Sbjct: 317 HQVVATNLPRIGYLTFMDGIVYVAFASVGLTML 349
>UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Glra4a protein -
Strongylocentrotus purpuratus
Length = 541
Score = 39.9 bits (89), Expect = 0.11
Identities = 21/75 (28%), Positives = 38/75 (50%)
Query: 133 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKI 192
R G+Y+ I + LIVI+++ SF + R A R+++ + +LP I
Sbjct: 299 RRPGFYIWNIALIMLLIVILTFTSFVVERGAPADRLSVTVTLLLTAVAFKYVVSQSLPLI 358
Query: 193 SYVKSIDVYLGTCFV 207
SY+ +D Y+ +C +
Sbjct: 359 SYLTMLDKYVLSCLI 373
>UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole
genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome
undetermined SCAF15016, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 269
Score = 39.9 bits (89), Expect = 0.11
Identities = 16/35 (45%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 188 ALPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGY 221
+LP + ++K+IDVYLG CF +F +L+EYA +
Sbjct: 232 SLPNANCFIKAIDVYLGICFSFIFGALIEYAVAHF 266
>UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1;
Synechococcus sp. WH 7805|Rep: Putative uncharacterized
protein - Synechococcus sp. (strain WH7805)
Length = 386
Score = 38.7 bits (86), Expect = 0.24
Identities = 32/152 (21%), Positives = 68/152 (44%), Gaps = 7/152 (4%)
Query: 92 VGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGL 148
V +S LP++K+ R + + + +SRL+ I R GYY+ +I++P G+
Sbjct: 216 VSLSRNARLPEWKIKDLRYVIKNHDDPEKGSKEFSRLSSTITISRRSGYYIYKIFLPLGI 275
Query: 149 IVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVM 208
+ S + +A R+A +++P++ Y+ D Y T F+
Sbjct: 276 LTFTSIFFLAIPIDAFADRMAFISGLLFTTLAYQIIIASSVPRVPYLTLGDTY--TIFLF 333
Query: 209 VFASLLEYATVGYMAKRIQMR-KQRFVAIQKI 239
F + E ++++ ++ +R AI+++
Sbjct: 334 TF-MISEVFIAYHISQNLRKNGSERVPAIERV 364
>UniRef50_A7I712 Cluster: Putative uncharacterized protein
precursor; n=1; Candidatus Methanoregula boonei 6A8|Rep:
Putative uncharacterized protein precursor -
Methanoregula boonei (strain 6A8)
Length = 337
Score = 38.7 bits (86), Expect = 0.24
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 9/135 (6%)
Query: 90 NSVGVSSEVSLPQFKVLGHRQRAMEISLTTGN--YSRLACEIQFVRSMGYYLIQIYIPSG 147
N+ G+ E +LP + + G + G YSR+ R L++ ++P
Sbjct: 167 NNTGLDDEANLPGWSLTGMSAEVTNRTYVEGEVPYSRVTFSNGIERDTASTLLKFFLPIT 226
Query: 148 LIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFV 207
LI+I+S S + T +R+ L A+P ++Y +D+++ +
Sbjct: 227 LIIIVSLASLLMK---TSSRLGLNGSMFLAAVLIHWRIADAIPLVAYATFLDLFM----I 279
Query: 208 MVFASLLEYATVGYM 222
+ +A+L+ G +
Sbjct: 280 ITYATLVMVCVSGIL 294
>UniRef50_UPI0000E4929C Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor beta 1 subunit variant 1; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor beta 1 subunit variant
1 - Strongylocentrotus purpuratus
Length = 472
Score = 38.3 bits (85), Expect = 0.32
Identities = 16/39 (41%), Positives = 25/39 (64%)
Query: 121 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL 159
NYS++ EI R Y++I + +PS LI +S V+FW+
Sbjct: 218 NYSKIHFEITLTRKSYYFVINLVLPSSLINAMSLVAFWV 256
>UniRef50_A0NGW8 Cluster: ENSANGP00000031454; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000031454 - Anopheles gambiae
str. PEST
Length = 476
Score = 38.3 bits (85), Expect = 0.32
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 226 IQMRKQRFVAIQKIASEKKLPECPPVGDPHTL-SKMNT-LSRCPPSRPSKTISQEVRFKV 283
++ +KQ+ I +S +P P + P T+ ++ N L+R PP +P +I + +R +
Sbjct: 174 LKKQKQQGSIISSSSSSGSVP--PAMNPPPTVPNEANLRLNRGPPPQPPTSIQRTIRRQR 231
Query: 284 ---HDPKAHSKGGTLENTINGG-RGGADEENPGPHPIHPGKDISKLLGMTPS 331
H P KG + G + GA +P PH H +S L G PS
Sbjct: 232 PHRHRPPPVRKGAYFRDGDGGDTQSGAQSRSPVPHSPHTHTCVSVLAGSKPS 283
>UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal
acetylcholine receptor subunit alpha-9 precursor; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
neuronal acetylcholine receptor subunit alpha-9
precursor - Strongylocentrotus purpuratus
Length = 510
Score = 36.3 bits (80), Expect = 1.3
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 86 NEGPN-SVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYI 144
NE PN SV + + V Q V + T YS++ E+ RS G+Y++ I +
Sbjct: 258 NEDPNQSVFLQNGVWSLQNSVAHQKNETYACCETP--YSQIVYELILERSYGFYVLNIVL 315
Query: 145 PSGLIVIISWVSFWL 159
PSGL+ ++ + F L
Sbjct: 316 PSGLLAFVNCLVFLL 330
>UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter
violaceus|Rep: Glr4197 protein - Gloeobacter violaceus
Length = 359
Score = 36.3 bits (80), Expect = 1.3
Identities = 24/116 (20%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
S+L +++ R Y+ I +P I+ ISW +FW + A V L
Sbjct: 224 SKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLVVSTLIAHIAFN 281
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQK 238
LPK Y+ + ++ F +++E Y+ +++ + R +I +
Sbjct: 282 ILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYL--KVESQPARAASITR 335
>UniRef50_Q5U3N0 Cluster: Pleckstrin homology domain-containing
family A member 8; n=5; Clupeocephala|Rep: Pleckstrin
homology domain-containing family A member 8 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 549
Score = 36.3 bits (80), Expect = 1.3
Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 2/73 (2%)
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
K L EC + T + + LSR PP PS + + K +DPK G T ++ IN
Sbjct: 166 KTLEECMHIAS-RTFNP-DLLSRTPPGSPSVATIKPQKIKSNDPKNLHPGETRKDLINTS 223
Query: 303 RGGADEENPGPHP 315
A E P P
Sbjct: 224 GTSAHESGPDNEP 236
>UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E;
n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor
3E - Homo sapiens (Human)
Length = 471
Score = 35.9 bits (79), Expect = 1.7
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340
>UniRef50_P02836 Cluster: Segmentation polarity homeobox protein
engrailed; n=9; Drosophila|Rep: Segmentation polarity
homeobox protein engrailed - Drosophila melanogaster
(Fruit fly)
Length = 552
Score = 35.9 bits (79), Expect = 1.7
Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 8/111 (7%)
Query: 230 KQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAH 289
K ++ K S+ P P + P S ++L+ PP+ + TIS +
Sbjct: 293 KSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSS 352
Query: 290 SKGGTLENTIN-------GGRG-GADEENPGPHPIHPGKDISKLLGMTPSD 332
S + +++N G G G + +P P PI P +S+ GM SD
Sbjct: 353 SGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSD 403
>UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precursor;
n=50; Tetrapoda|Rep: 5-hydroxytryptamine receptor 3
precursor - Homo sapiens (Human)
Length = 478
Score = 35.9 bits (79), Expect = 1.7
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform
b; n=4; Caenorhabditis|Rep: Acetylcholine receptor
protein 17, isoform b - Caenorhabditis elegans
Length = 515
Score = 35.5 bits (78), Expect = 2.3
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 5/93 (5%)
Query: 133 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVALGXXXXXXXXXXXXXXNAAL 189
R+ YYL + IPS I I++ + F+ ++T +V+LG + L
Sbjct: 243 RNPSYYLFTLIIPSAFITIVTVIGFFTPHSSTGENTEKVSLGVTALLSLAIILMMVSDKL 302
Query: 190 PKISYVKSI--DVYLGTCFVMVFASLLEYATVG 220
P S + Y+G F+M A+ T+G
Sbjct: 303 PATSNSVPLLGQYYIGLIFIMFLATYCTTFTLG 335
>UniRef50_Q4R170 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 404
Score = 35.5 bits (78), Expect = 2.3
Identities = 19/86 (22%), Positives = 38/86 (44%)
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
E F R+ G+Y++ + IP+ I ++S V+ +++ N + +G
Sbjct: 254 EATFSRNPGFYIVLVMIPAYFINVLSIVALFMDINNRSEKFTVGMTNIMSMSFILVILAE 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASL 213
LPK + + +Y T ++ SL
Sbjct: 314 DLPKTKNLPILAIYTVTSLAIMLCSL 339
>UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-18 - Caenorhabditis elegans
Length = 510
Score = 35.5 bits (78), Expect = 2.3
Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 133 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNAT---PARVALGXXXXXXXXXXXXXXNAAL 189
RS YY+ + IPS I +++ V F+ + T +V+LG + +
Sbjct: 235 RSPSYYIFSLVIPSAFITVVTIVGFFTPHSTTGENTEKVSLGVTALLSMAIIMMMVSDEV 294
Query: 190 PKISYVKSI--DVYLGTCFVMVFASLLEYATVGYMAK 224
P S V + Y+G F++ A+ T+ Y +
Sbjct: 295 PATSEVIPLIGKYYIGLIFLIFMAAFTTTLTLSYQMR 331
>UniRef50_Q0V237 Cluster: Predicted protein; n=1; Phaeosphaeria
nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
(Septoria nodorum)
Length = 583
Score = 35.1 bits (77), Expect = 3.0
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 261 NTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLE--------NTINGGRGGADEENPG 312
+T SR PPS PS E R + H+ HS L+ GG G D P
Sbjct: 57 STTSRLPPSPPSTPRGPEARSEKHENAEHSTQKPLKTFQPQDPPKAEGGGWSGWDAPRPD 116
Query: 313 PHPIHPGKD 321
P P+ P K+
Sbjct: 117 PPPVAPKKE 125
>UniRef50_A5DNF5 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 417
Score = 35.1 bits (77), Expect = 3.0
Identities = 15/39 (38%), Positives = 25/39 (64%)
Query: 304 GGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFP 342
G E+PGP P P +++S LL + S +++Y+R+V P
Sbjct: 30 GSVRAESPGPTPGSPQQNLSSLLNIPDSFLEQYTRMVKP 68
>UniRef50_UPI00006CC8B0 Cluster: hypothetical protein
TTHERM_00290740; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00290740 - Tetrahymena
thermophila SB210
Length = 679
Score = 34.7 bits (76), Expect = 4.0
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 190 PKISYVKSIDVYLGTCF-VMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
PK + KS+ +L C +L ATVG+ K I++ KQR A+QKI ++
Sbjct: 336 PKKDFQKSLYSFLLACQDFRDLQIILAKATVGFWKKSIELEKQRSKAVQKIVTD 389
>UniRef50_Q0KI87 Cluster: CG11870-PA, isoform A; n=3; Drosophila
melanogaster|Rep: CG11870-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 1427
Score = 34.7 bits (76), Expect = 4.0
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 3/77 (3%)
Query: 250 PVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEE 309
P HT S +T +R PSR ++ E F P K T T +G GGA+EE
Sbjct: 1218 PSESSHTTSSRSTFTRLRPSRRIGSLLSEAGFDEGSP--FQKMRTTSITRDGVSGGAEEE 1275
Query: 310 -NPGPHPIHPGKDISKL 325
PH + + + K+
Sbjct: 1276 ARFTPHRLRSSRPVKKI 1292
>UniRef50_Q0CS36 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 1020
Score = 34.7 bits (76), Expect = 4.0
Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 212 SLLEYATVGYMAKRIQMRKQRFVAI---QKIASEKKLPECPPVGDPHTLSKMNTLSRCPP 268
S E + G + ++ R++R+ A+ + A+ + P+ PP G P +S + + + PP
Sbjct: 802 SAAEVLSFGELPDHVKARQERYYAMVNPNRAATAQPAPQNPPNGAPFDISNLLKILQKPP 861
Query: 269 SR-PSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI 316
+ P + + P + LE TI+ R + P P+P+
Sbjct: 862 QQAPGQNSTPP---PAPQPTSQPPMFDLERTISMFRQQQQPQQPAPNPL 907
>UniRef50_O16426 Cluster: Ligand-gated ion channel protein 1; n=2;
Caenorhabditis elegans|Rep: Ligand-gated ion channel
protein 1 - Caenorhabditis elegans
Length = 371
Score = 34.3 bits (75), Expect = 5.2
Identities = 22/113 (19%), Positives = 50/113 (44%), Gaps = 1/113 (0%)
Query: 120 GNYSRLACEIQFV-RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXX 178
GN+S + + + R+ G+Y+ + +P+ I +S ++ LN ++ +G
Sbjct: 218 GNFSAVQRFVARIERNPGFYVTLVMVPAFFINFLSIIALCLNIENVGEKITVGLTNIMAM 277
Query: 179 XXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQ 231
LPK + + +Y+ V+V AS+ T+ + ++ R++
Sbjct: 278 TFILVILAQDLPKTKRIPLLAIYVIVGLVIVMASIGVVLTLPLIRNHLKKRQK 330
>UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-type
des-2 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type des-2 precursor -
Caenorhabditis elegans
Length = 548
Score = 34.3 bits (75), Expect = 5.2
Identities = 42/229 (18%), Positives = 92/229 (40%), Gaps = 16/229 (6%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTT--GNYSRL 125
V T+T +T + + +G S+ + + +L + + E+ NY+ L
Sbjct: 169 VCTMTFSSWTYDQKGIDYFPYSDKIGTSNYLENEGWYILQTKIKRQEVKYACCPNNYTLL 228
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR---VALGXXXXXXXXXXX 182
+ R +YL+ + IP+ +I +I+ V F+ +A+ R V+LG
Sbjct: 229 QLTLYLRRKPLFYLVNLIIPTSIITLIAIVGFFTTSSASGMREEKVSLGITTLLSMSILM 288
Query: 183 XXXNAALPKIS-YVKSIDVYLGTCFVMVFASLLEYATV------GYMAKRIQMRKQRFVA 235
+ +P S ++ I ++ +++ + + + G + +R+ R +F
Sbjct: 289 LMVSDQMPTTSTFIPLIGWFILAMIIVISLGTVVSSVIIAIQKRGSLGERMSKRALKFAK 348
Query: 236 IQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSK--TISQEVRFK 282
+ + LP P V H + + + RP + ++ + VR K
Sbjct: 349 VLAWFTCTSLP--PHVEKEHMMEAFDAPTPLVEVRPLQLASVKESVRNK 395
>UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3
subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine
receptor 3 subunit D - Xenopus tropicalis
Length = 415
Score = 33.9 bits (74), Expect = 6.9
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 138 YLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISY-VK 196
Y++ + +PS +++I +SF+L ++T R + N LP +
Sbjct: 196 YVVNLLVPSAFLMLIDILSFFLPPHSTD-RASFKMTLLLGYTVFLLIMNDLLPSTANGTP 254
Query: 197 SIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
I +Y C ++ SLLE + ++ R M+
Sbjct: 255 LIGIYFSVCLALLVLSLLETVIITHVMHRGAMQ 287
>UniRef50_Q05QM7 Cluster: Putative uncharacterized protein; n=1;
Synechococcus sp. RS9916|Rep: Putative uncharacterized
protein - Synechococcus sp. RS9916
Length = 366
Score = 33.9 bits (74), Expect = 6.9
Identities = 18/93 (19%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 120 GNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXX 179
G Y E+ + R+ G Q+ +P G++ +++++ ++ A A++AL
Sbjct: 221 GVYPNFLAEVSYTRNFGSSSWQLLLPLGIVSAVAFLTPMIDARAAEAKIALPASVILTLV 280
Query: 180 XXXXXXNAAL-PKISYVKSIDVYLGTCFVMVFA 211
L P +SY+ +D + + ++ A
Sbjct: 281 FLQDGYKQMLPPSLSYLTLLDKFYISMYLSTLA 313
>UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD)
alternative variant a; n=5; Caenorhabditis|Rep:
Acetylcholine receptor 20 (63.9 kD) alternative variant
a - Caenorhabditis elegans
Length = 553
Score = 33.9 bits (74), Expect = 6.9
Identities = 23/109 (21%), Positives = 47/109 (43%), Gaps = 4/109 (3%)
Query: 121 NYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR---VALGXXXXXX 177
NY+ L + R YY+I + IP+ +I IS + F+ + R + LG
Sbjct: 224 NYTLLEFRLTIQRKPLYYIINLIIPTSIITFISIIGFFSTSSINEPREEKITLGFTTLLS 283
Query: 178 XXXXXXXXNAALPKI-SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
+ +P S++ I ++ + +++ S + + V Y+ K+
Sbjct: 284 MSILIFMVSDKMPSTSSFIPLIGLFYTSMILLISFSTICSSVVIYVQKQ 332
>UniRef50_A7F7D1 Cluster: Predicted protein; n=1; Sclerotinia
sclerotiorum 1980|Rep: Predicted protein - Sclerotinia
sclerotiorum 1980
Length = 258
Score = 33.9 bits (74), Expect = 6.9
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 249 PPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADE 308
PP DP+ MN S PS+ F++H P+A ++ G T+N G
Sbjct: 92 PPSYDPNPSPNMNEKSHTQNQTPSQ-------FQIH-PEAQNQNGNQNQTMNQNIPGNQY 143
Query: 309 ENPGPHPIHPGKDISKLLGMTPSDIDKYSRI 339
EN P P+ + S+L+ + +Y+++
Sbjct: 144 ENQHPAPLTTLQKESRLVRCPRCGVLEYTQV 174
>UniRef50_UPI0000F2D592 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 386
Score = 33.5 bits (73), Expect = 9.2
Identities = 25/78 (32%), Positives = 34/78 (43%), Gaps = 10/78 (12%)
Query: 246 PECPPV----GDPHTLSK-----MNTLSRCPPSRPSKTISQEVRF-KVHDPKAHSKGGTL 295
P CPPV P +L++ M + C PSRPS + D + GG L
Sbjct: 177 PRCPPVRGAAAPPQSLAERKGAEMPLENLCGPSRPSPQPRPAPTLGRAGDAPSPGPGGQL 236
Query: 296 ENTINGGRGGADEENPGP 313
+ +GGRG + E GP
Sbjct: 237 PGSESGGRGSDEAEASGP 254
>UniRef50_Q8A0N7 Cluster: Putative uncharacterized protein; n=1;
Bacteroides thetaiotaomicron|Rep: Putative
uncharacterized protein - Bacteroides thetaiotaomicron
Length = 537
Score = 33.5 bits (73), Expect = 9.2
Identities = 15/49 (30%), Positives = 27/49 (55%)
Query: 88 GPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMG 136
G + VG+ + +P+ K GH+ + I+ T+ Y A E+ F+R+ G
Sbjct: 324 GQDYVGMRRGIVIPELKTTGHKYSGVNIAPTSPLYWMNAAEVAFLRAEG 372
>UniRef50_P73566 Cluster: Slr0882 protein; n=9; Cyanobacteria|Rep:
Slr0882 protein - Synechocystis sp. (strain PCC 6803)
Length = 394
Score = 33.5 bits (73), Expect = 9.2
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)
Query: 98 VSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFV--RSMGYYLIQIYIPSGLI-VIISW 154
+ +P+F VL + SL YSRL+ + + + RS+G + ++ +P+ L ++++
Sbjct: 75 LKMPEFVVLAFPMSMLLASLMA--YSRLSSDSELIALRSIGVSIYRLVVPALLFGIVVTG 132
Query: 155 VSFWLNRNATPA 166
++F N TPA
Sbjct: 133 IAFVFNDRITPA 144
>UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG10413 - Caenorhabditis
briggsae
Length = 366
Score = 33.5 bits (73), Expect = 9.2
Identities = 19/95 (20%), Positives = 42/95 (44%)
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
+F R+ G+Y+ + +P+ I +S + ++N ++ +G A L
Sbjct: 248 RFQRNPGFYVALVMVPAFFINFLSIFALFVNVENLSEKITVGLTNIMAMTFILVILAADL 307
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK 224
PK + + + +Y+ V+V S+ + Y+ K
Sbjct: 308 PKTARIPLLAIYVIVGLVIVMTSIGICLLIPYIRK 342
>UniRef50_Q6EEV4 Cluster: GRINL1A downstream protein Gdown4; n=1;
Homo sapiens|Rep: GRINL1A downstream protein Gdown4 -
Homo sapiens (Human)
Length = 148
Score = 33.5 bits (73), Expect = 9.2
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 6/95 (6%)
Query: 239 IASEKKLPECPPVGDPHTLSKMNTLSRCPPSR---PSKTISQEVRFKVHDPK---AHSKG 292
+A+ + PE PP DP ++ + CPP R P++ + R + + A G
Sbjct: 1 MATPARAPESPPSADPALVAGPAEEAECPPPRQPQPAQNVLAAPRLRAPSSRGLGAAEFG 60
Query: 293 GTLENTINGGRGGADEENPGPHPIHPGKDISKLLG 327
G N G A + GP PG S LG
Sbjct: 61 GAAGNVEAPGETFAQRVSWGPAESPPGSFSSSSLG 95
>UniRef50_Q0URS6 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 736
Score = 33.5 bits (73), Expect = 9.2
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 204 TCFVMVFASLLEYATVG-YMAKRIQMRKQ-RFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
T ++ F +LL Y V ++A R RK ++ A+ + PPV D H LS +
Sbjct: 8 TAVLLAFMALLAYKEVRKFLANRRSRRKHLETPGSRRYAATNDIK--PPVDD-HGLSSLY 64
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAH 289
++ P P +++ FK+H+ + H
Sbjct: 65 VTAKADPMNPEFQAHKQLYFKLHNLEHH 92
>UniRef50_A4R7R7 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 734
Score = 33.5 bits (73), Expect = 9.2
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 223 AKRIQMRKQRFVAIQ-KIASEKKLPECPPVGDPHTLSK-----MNTL--SRCP-PSRPSK 273
+K+ ++K+R ++ + K KK P H SK ++T+ S+ P PS P K
Sbjct: 418 SKKEALKKERSISAEVKSPPAKKRPRAAEPIVEHVASKRPRSSLDTILVSKAPAPSTPLK 477
Query: 274 TISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDIS 323
+ R + +AH+ GGT NG GA + P H P K +S
Sbjct: 478 QATAMSRAASSNSQAHTPGGT-----NGLTPGAGDRPPTSHEGDPAKGVS 522
>UniRef50_Q8NFW5 Cluster: Diencephalon/mesencephalon homeobox
protein 1; n=46; Euteleostomi|Rep:
Diencephalon/mesencephalon homeobox protein 1 - Homo
sapiens (Human)
Length = 382
Score = 33.5 bits (73), Expect = 9.2
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 169 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 226
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
RG ++PG I P LLG + S
Sbjct: 227 RGSPKADSPGSLTITPVAPGGGLLGPSHS 255
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.322 0.137 0.420
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 417,065,022
Number of Sequences: 1657284
Number of extensions: 16825059
Number of successful extensions: 37377
Number of sequences better than 10.0: 164
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 36986
Number of HSP's gapped (non-prelim): 354
length of query: 374
length of database: 575,637,011
effective HSP length: 102
effective length of query: 272
effective length of database: 406,594,043
effective search space: 110593579696
effective search space used: 110593579696
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 73 (33.5 bits)
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