Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000568-TA|BGIBMGA000568-PA|IPR006202|Neurotransmitter-
gated ion-channel ligand-binding, IPR006029|Neurotransmitter-gated
ion-channel transmembrane region, IPR006028|Gamma-aminobutyric acid A
receptor, IPR002289|Gamma-aminobutyric-acid A receptor, beta subunit,
IPR006201|Neurotransmitter-gated ion-channel
(374 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 171 3e-42
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 171 3e-42
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 171 3e-42
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 159 2e-38
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 159 2e-38
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 159 2e-38
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 159 2e-38
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 159 2e-38
M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-... 156 1e-37
BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid... 155 2e-37
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 148 3e-35
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 148 3e-35
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 142 2e-33
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 142 2e-33
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 142 2e-33
M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid ... 142 2e-33
BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid... 141 3e-33
BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid... 141 3e-33
AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid... 141 3e-33
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 140 6e-33
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 140 6e-33
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 140 6e-33
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 140 6e-33
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 140 6e-33
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 140 6e-33
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 140 6e-33
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 140 6e-33
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 140 6e-33
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 140 7e-33
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 140 7e-33
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 140 7e-33
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 140 7e-33
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 137 7e-32
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 137 7e-32
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 136 9e-32
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 136 2e-31
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 136 2e-31
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 136 2e-31
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 132 3e-30
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 132 3e-30
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 132 3e-30
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 132 3e-30
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 130 8e-30
U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta sub... 130 1e-29
BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta ... 130 1e-29
AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta s... 130 1e-29
AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta s... 130 1e-29
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 128 2e-29
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 128 2e-29
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 128 2e-29
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 128 2e-29
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 128 2e-29
M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid r... 127 5e-29
BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid... 127 5e-29
AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid... 127 5e-29
AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid... 127 5e-29
X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1 s... 125 2e-28
BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein. 125 2e-28
AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid... 125 2e-28
AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha ... 124 4e-28
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 124 5e-28
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 124 5e-28
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 124 5e-28
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 124 5e-28
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 124 5e-28
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 124 5e-28
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 122 2e-27
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 120 8e-27
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 114 4e-25
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 114 4e-25
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 114 4e-25
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 114 4e-25
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 114 4e-25
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 114 4e-25
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 113 7e-25
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 113 1e-24
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 112 2e-24
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 112 2e-24
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 112 2e-24
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 112 2e-24
S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA ... 110 9e-24
BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein. 110 9e-24
AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid... 110 9e-24
X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for ... 106 1e-22
Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chlor... 95 3e-19
Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon sub... 95 4e-19
U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon s... 95 4e-19
U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon s... 95 4e-19
BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein. 95 4e-19
BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein. 95 4e-19
BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein. 95 4e-19
Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein. 93 2e-18
AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein. 69 3e-11
AF228449-1|AAF62510.1| 70|Homo sapiens gamma-aminobutyric acid... 46 2e-04
AK127001-1|BAC86784.1| 133|Homo sapiens protein ( Homo sapiens ... 42 0.004
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 41 0.006
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 41 0.006
Y18994-1|CAB60835.1| 99|Homo sapiens GABA-C receptor rho3 subu... 41 0.008
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 36 0.23
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 36 0.23
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 36 0.23
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 36 0.23
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 36 0.23
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 36 0.23
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 36 0.23
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 36 0.23
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 36 0.23
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 36 0.23
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 36 0.23
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 36 0.23
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 36 0.23
AY341344-1|AAQ76830.1| 148|Homo sapiens GRINL1A downstream prot... 33 1.2
AL137797-2|CAI19184.1| 377|Homo sapiens diencephalon/mesencepha... 33 1.2
AL137797-1|CAI19185.1| 382|Homo sapiens diencephalon/mesencepha... 33 1.2
AF398528-1|AAM90590.1| 382|Homo sapiens homeoprotein MBX-L prot... 33 1.2
AF398527-1|AAM90589.1| 377|Homo sapiens homeoprotein MBX-S prot... 33 1.2
AJ437318-1|CAD24817.1| 454|Homo sapiens 5-hydroxytryptamine 3-r... 33 1.6
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 32 2.9
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 32 2.9
AB037699-1|BAC00920.1| 382|Homo sapiens PaxB protein. 32 2.9
AL133561-1|CAB63715.1| 580|Homo sapiens hypothetical protein pr... 31 8.7
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 171 bits (417), Expect = 3e-42
Identities = 115/349 (32%), Positives = 174/349 (49%), Gaps = 22/349 (6%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 132 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ WN G +V +++ LPQF ++ ++ + ++ TTG Y RL+ + R++GY+++Q
Sbjct: 191 FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQT 250
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 251 YMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYL 310
Query: 203 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVG-DPHTLSKMN 261
CFV VF +LLEYA V Y+ +K+ + A+EK E V D H ++
Sbjct: 311 MGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLS 370
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKA-----HSKGGTLENTING--GRGGADEENPGPH 314
TL ++T EV V DPKA S ++ G A + + P
Sbjct: 371 TL-----EIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPS 425
Query: 315 PIHPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L P + IDK+SR+ FP+ F FN++YW+ Y+H
Sbjct: 426 KGRNRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 171 bits (416), Expect = 3e-42
Identities = 115/349 (32%), Positives = 174/349 (49%), Gaps = 22/349 (6%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 132 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ WN G +V +++ LPQF ++ ++ + ++ TTG Y RL+ + R++GY+++Q
Sbjct: 191 FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQT 250
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 251 YMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYL 310
Query: 203 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVG-DPHTLSKMN 261
CFV VF +LLEYA V Y+ +K+ + A+EK E V D H ++
Sbjct: 311 MGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLS 370
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKA-----HSKGGTLENTING--GRGGADEENPGPH 314
TL ++T EV V DPKA S ++ G A + + P
Sbjct: 371 TL-----EIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPS 425
Query: 315 PIHPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L P + IDK+SR+ FP+ F FN++YW+ Y+H
Sbjct: 426 KGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 171 bits (416), Expect = 3e-42
Identities = 115/349 (32%), Positives = 174/349 (49%), Gaps = 22/349 (6%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 132 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ WN G +V +++ LPQF ++ ++ + ++ TTG Y RL+ + R++GY+++Q
Sbjct: 191 FYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQT 250
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 251 YMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYL 310
Query: 203 GTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVG-DPHTLSKMN 261
CFV VF +LLEYA V Y+ +K+ + A+EK E V D H ++
Sbjct: 311 MGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLS 370
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKA-----HSKGGTLENTING--GRGGADEENPGPH 314
TL ++T EV V DPKA S ++ G A + + P
Sbjct: 371 TL-----EIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPS 425
Query: 315 PIHPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L P + IDK+SR+ FP+ F FN++YW+ Y+H
Sbjct: 426 KGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 474
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 159 bits (385), Expect = 2e-38
Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 25/351 (7%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM-AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
CFV VF +LLEYA V Y+ R R+++ A+ +K+ DPH ++
Sbjct: 310 MGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLS 369
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI--HPG 319
TL ++ + E + DP++ ++I + G + G + + H
Sbjct: 370 TL-----EIKNEMATSEAVMGLGDPRSTMLAYD-ASSIQYRKAGLPRHSFGRNALERHVA 423
Query: 320 KDISKL------LGMTPSD------IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L L +T D ID++SRI FPV F FN++YW+ Y++
Sbjct: 424 QKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 159 bits (385), Expect = 2e-38
Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 25/351 (7%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM-AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
CFV VF +LLEYA V Y+ R R+++ A+ +K+ DPH ++
Sbjct: 310 MGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLS 369
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI--HPG 319
TL ++ + E + DP++ ++I + G + G + + H
Sbjct: 370 TL-----EIKNEMATSEAVMGLGDPRSTMLAYD-ASSIQYRKAGLPRHSFGRNALERHVA 423
Query: 320 KDISKL------LGMTPSD------IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L L +T D ID++SRI FPV F FN++YW+ Y++
Sbjct: 424 QKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 159 bits (385), Expect = 2e-38
Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 25/351 (7%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM-AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
CFV VF +LLEYA V Y+ R R+++ A+ +K+ DPH ++
Sbjct: 310 MGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLS 369
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI--HPG 319
TL ++ + E + DP++ ++I + G + G + + H
Sbjct: 370 TL-----EIKNEMATSEAVMGLGDPRSTMLAYD-ASSIQYRKAGLPRHSFGRNALERHVA 423
Query: 320 KDISKL------LGMTPSD------IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L L +T D ID++SRI FPV F FN++YW+ Y++
Sbjct: 424 QKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 159 bits (385), Expect = 2e-38
Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 25/351 (7%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM-AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
CFV VF +LLEYA V Y+ R R+++ A+ +K+ DPH ++
Sbjct: 310 MGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLS 369
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI--HPG 319
TL ++ + E + DP++ ++I + G + G + + H
Sbjct: 370 TL-----EIKNEMATSEAVMGLGDPRSTMLAYD-ASSIQYRKAGLPRHSFGRNALERHVA 423
Query: 320 KDISKL------LGMTPSD------IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L L +T D ID++SRI FPV F FN++YW+ Y++
Sbjct: 424 QKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 159 bits (385), Expect = 2e-38
Identities = 109/351 (31%), Positives = 177/351 (50%), Gaps = 25/351 (7%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM-AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMN 261
CFV VF +LLEYA V Y+ R R+++ A+ +K+ DPH ++
Sbjct: 310 MGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNKMDPHENILLS 369
Query: 262 TLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGPHPI--HPG 319
TL ++ + E + DP++ ++I + G + G + + H
Sbjct: 370 TL-----EIKNEMATSEAVMGLGDPRSTMLAYD-ASSIQYRKAGLPRHSFGRNALERHVA 423
Query: 320 KDISKL------LGMTPSD------IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ S+L L +T D ID++SRI FPV F FN++YW+ Y++
Sbjct: 424 QKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN 474
>M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-3
subunit protein.
Length = 473
Score = 156 bits (378), Expect = 1e-37
Identities = 109/347 (31%), Positives = 165/347 (47%), Gaps = 19/347 (5%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 132 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 190
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W G +V + LPQF ++ HR + + TG Y RL+ + R++GY+++Q
Sbjct: 191 FYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQT 250
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 251 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 310
Query: 203 GTCFVMVFASLLEYATVGYM--AKRIQMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKM 260
CFV VF +LLEYA V Y+ + Q +K+ K +++ E V D H +
Sbjct: 311 MGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRV-DAHGNILL 369
Query: 261 NTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGG---TLENTINGGRGGADEENPGPH-PI 316
+L +S + + + G ++ G G + PH
Sbjct: 370 TSLE---VHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKT 426
Query: 317 HPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
H + S+L P + ID++SRIVFP F FNL+YW+ Y++
Sbjct: 427 HLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473
>BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 3 protein.
Length = 473
Score = 155 bits (377), Expect = 2e-37
Identities = 99/301 (32%), Positives = 149/301 (49%), Gaps = 15/301 (4%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ + + GYT DI + W G +V + LPQF ++ HR + + TG Y RL+
Sbjct: 177 LEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLS 236
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++GY+++Q Y+PS LI I+SWVSFW+N +A+ ARVALG
Sbjct: 237 FRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRET 296
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM--AKRIQMRKQRFVAIQKIASEKKLP 246
LPKI YVK+ID+YL CFV VF +LLEYA V Y+ + Q +K+ K +++
Sbjct: 297 LPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKS 356
Query: 247 ECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGG---TLENTINGGR 303
E V D H + +L +S + + + G ++ G
Sbjct: 357 ESNRV-DAHGNILLTSLE---VHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGH 412
Query: 304 GGADEENPGPH-PIHPGKDISKLLGMTP-----SDIDKYSRIVFPVCFVCFNLMYWIIYL 357
G + PH H + S+L P + ID++SRIVFP F FNL+YW+ Y+
Sbjct: 413 GRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYV 472
Query: 358 H 358
+
Sbjct: 473 N 473
Score = 41.1 bits (92), Expect = 0.006
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYK 84
GYT DI ++W+ G +V ++LPQF ++ HR + + T Y + ++
Sbjct: 183 GYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFR 238
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 148 bits (359), Expect = 3e-35
Identities = 99/295 (33%), Positives = 147/295 (49%), Gaps = 35/295 (11%)
Query: 68 VITLTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRL 125
++ L + GYTM D+ ++W +E P V V+ ++LPQF + + R TG ++ +
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCI 243
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG
Sbjct: 244 EVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGS 303
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKL 245
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ RF +K +E
Sbjct: 304 RASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-HKELLRFRRKRKNKTEA-- 360
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
L K S + EVR A+ G L+ + G
Sbjct: 361 ---------FALEKFYRFS---------DMDDEVRESRFSFTAYGMGPCLQ-----AKDG 397
Query: 306 ADEENPGPHPIH----PGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
+ P HP+ ++ K+ ID SR FP+ F+ FN+ YW+IY
Sbjct: 398 MTPKGPN-HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 148 bits (359), Expect = 3e-35
Identities = 99/295 (33%), Positives = 147/295 (49%), Gaps = 35/295 (11%)
Query: 68 VITLTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRL 125
++ L + GYTM D+ ++W +E P V V+ ++LPQF + + R TG ++ +
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCI 243
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG
Sbjct: 244 EVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGS 303
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKL 245
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ RF +K +E
Sbjct: 304 RASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-HKELLRFRRKRKNKTEA-- 360
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
L K S + EVR A+ G L+ + G
Sbjct: 361 ---------FALEKFYRFS---------DMDDEVRESRFSFTAYGMGPCLQ-----AKDG 397
Query: 306 ADEENPGPHPIH----PGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
+ P HP+ ++ K+ ID SR FP+ F+ FN+ YW+IY
Sbjct: 398 MTPKGPN-HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 451
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 142 bits (344), Expect = 2e-33
Identities = 68/178 (38%), Positives = 108/178 (60%), Gaps = 5/178 (2%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEI 129
L + GYTM+D+ ++W E +V V+ ++LPQF + + TG ++ + +
Sbjct: 149 LESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKF 208
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARV LG A+L
Sbjct: 209 HLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASL 268
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
PK+SYVK+ID+++ C + VFA+LLEYA + ++++ + + F+ +++ ++L E
Sbjct: 269 PKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSR----QHKEFIRLRRRQRRQRLEE 322
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 142 bits (344), Expect = 2e-33
Identities = 68/178 (38%), Positives = 108/178 (60%), Gaps = 5/178 (2%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACEI 129
L + GYTM+D+ ++W E +V V+ ++LPQF + + TG ++ + +
Sbjct: 149 LESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHYNTGKFTCIEVKF 208
Query: 130 QFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAAL 189
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARV LG A+L
Sbjct: 209 HLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASL 268
Query: 190 PKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
PK+SYVK+ID+++ C + VFA+LLEYA + ++++ + + F+ +++ ++L E
Sbjct: 269 PKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSR----QHKEFIRLRRRQRRQRLEE 322
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 142 bits (343), Expect = 2e-33
Identities = 74/200 (37%), Positives = 112/200 (56%), Gaps = 4/200 (2%)
Query: 26 YGVGYTMRDIRYHWKDGHSSVGM---SNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIR 82
+GV R IR H DG G+ + + R ++ + + + GYT DI
Sbjct: 131 HGVTVKNRMIRLH-PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIE 189
Query: 83 YKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQI 142
+ W N+V +++ LPQF ++ ++ ++ +TG+Y RL+ + R++GY+++Q
Sbjct: 190 FYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQT 249
Query: 143 YIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYL 202
Y+PS LI I+SWVSFW+N +A+ ARVALG LPKI YVK+ID+YL
Sbjct: 250 YMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYL 309
Query: 203 GTCFVMVFASLLEYATVGYM 222
CFV VF +LLEYA V Y+
Sbjct: 310 MGCFVFVFMALLEYALVNYI 329
Score = 39.1 bits (87), Expect = 0.025
Identities = 14/26 (53%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
ID++SRI FPV F FN++YW+ Y++
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYYVN 512
>M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid
protein.
Length = 465
Score = 142 bits (343), Expect = 2e-33
Identities = 88/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ ++SL QF + H + +TG Y+RL
Sbjct: 194 LELESYAYTDEDLMLHWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 253
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG NA
Sbjct: 254 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNA 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SYVK++D+YL FV VF S+LEYA V Y+ +Q RK E+KL E
Sbjct: 314 SMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT-VQERK-----------ERKLRE 361
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
P SK L + +++ R + + + ++G A
Sbjct: 362 KFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAAR 421
Query: 308 EENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
++ + G+ ++ T + IDKYSR++FP ++ FNL+YW ++
Sbjct: 422 KKG-----LLKGQTGFRIFQNTHA-IDKYSRLIFPASYIFFNLIYWSVF 464
Score = 31.1 bits (67), Expect = 6.6
Identities = 13/50 (26%), Positives = 24/50 (48%)
Query: 30 YTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMR 79
YT D+ HWK+G S+ ++ L QF + + + ++ G+ R
Sbjct: 201 YTDEDLMLHWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNR 250
>BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 141 bits (342), Expect = 3e-33
Identities = 88/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ ++SL QF + H + +TG Y+RL
Sbjct: 194 LELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 253
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG NA
Sbjct: 254 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNA 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SYVK++D+YL FV VF S+LEYA V Y+ +Q RK E+KL E
Sbjct: 314 SMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT-VQERK-----------ERKLRE 361
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
P SK L + +++ R + + + ++G A
Sbjct: 362 KFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAAR 421
Query: 308 EENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
++ + G+ ++ T + IDKYSR++FP ++ FNL+YW ++
Sbjct: 422 KKG-----LLKGQTGFRIFQNTHA-IDKYSRLIFPASYIFFNLIYWSVF 464
>BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 141 bits (342), Expect = 3e-33
Identities = 88/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ ++SL QF + H + +TG Y+RL
Sbjct: 194 LELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 253
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG NA
Sbjct: 254 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNA 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SYVK++D+YL FV VF S+LEYA V Y+ +Q RK E+KL E
Sbjct: 314 SMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT-VQERK-----------ERKLRE 361
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
P SK L + +++ R + + + ++G A
Sbjct: 362 KFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAAR 421
Query: 308 EENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
++ + G+ ++ T + IDKYSR++FP ++ FNL+YW ++
Sbjct: 422 KKG-----LLKGQTGFRIFQNTHA-IDKYSRLIFPASYIFFNLIYWSVF 464
>AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 141 bits (342), Expect = 3e-33
Identities = 88/289 (30%), Positives = 143/289 (49%), Gaps = 19/289 (6%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ L + YT D+ W G S+ ++SL QF + H + +TG Y+RL
Sbjct: 194 LELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFYSSTGWYNRLYI 253
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV+LG NA
Sbjct: 254 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTMTTIITGVNA 313
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SYVK++D+YL FV VF S+LEYA V Y+ +Q RK E+KL E
Sbjct: 314 SMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTT-VQERK-----------ERKLRE 361
Query: 248 CPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGAD 307
P SK L + +++ R + + + ++G A
Sbjct: 362 KFPCMCGMLHSKTMMLDGSYSESEANSLAGYPRSHILTEEERQDKIVVHLGLSGEANAAR 421
Query: 308 EENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
++ + G+ ++ T + IDKYSR++FP ++ FNL+YW ++
Sbjct: 422 KKG-----LLKGQTGFRIFQNTHA-IDKYSRLIFPASYIFFNLIYWSVF 464
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 140 bits (340), Expect = 6e-33
Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 16/227 (7%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLA 126
++ L + GYTM D+ ++W E +V V+ ++LPQF + + R TG ++ +
Sbjct: 181 IMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIE 239
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
R MGYYLIQ+YIPS LIVI+SW+SFW+N +A PARV LG
Sbjct: 240 ARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSR 299
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR----IQMRKQRFVAIQKIASE 242
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ ++ R++R + A E
Sbjct: 300 ASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGE 359
Query: 243 KKL--------PECPPVGDPHTLSKMNTLSRC-PPSRPSKTISQEVR 280
+ P C D ++ N + PP PSK+ +E+R
Sbjct: 360 GRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKS-PEEMR 405
Score = 51.6 bits (118), Expect = 4e-06
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G ++ NP P P +++ KL IDK SRI FP+ F+ FN+ YWIIY
Sbjct: 384 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 140 bits (340), Expect = 6e-33
Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 16/227 (7%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLA 126
++ L + GYTM D+ ++W E +V V+ ++LPQF + + R TG ++ +
Sbjct: 98 IMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIE 156
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
R MGYYLIQ+YIPS LIVI+SW+SFW+N +A PARV LG
Sbjct: 157 ARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSR 216
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR----IQMRKQRFVAIQKIASE 242
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ ++ R++R + A E
Sbjct: 217 ASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGE 276
Query: 243 KKL--------PECPPVGDPHTLSKMNTLSRC-PPSRPSKTISQEVR 280
+ P C D ++ N + PP PSK+ +E+R
Sbjct: 277 GRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKS-PEEMR 322
Score = 51.6 bits (118), Expect = 4e-06
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G ++ NP P P +++ KL IDK SRI FP+ F+ FN+ YWIIY
Sbjct: 301 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 355
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia, stiff man syndrome)
protein.
Length = 449
Score = 140 bits (340), Expect = 6e-33
Identities = 80/227 (35%), Positives = 126/227 (55%), Gaps = 16/227 (7%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLA 126
++ L + GYTM D+ ++W E +V V+ ++LPQF + + R TG ++ +
Sbjct: 181 IMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIE 239
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
R MGYYLIQ+YIPS LIVI+SW+SFW+N +A PARV LG
Sbjct: 240 ARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSR 299
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR----IQMRKQRFVAIQKIASE 242
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++ ++ R++R + A E
Sbjct: 300 ASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKEDEAGE 359
Query: 243 KKL--------PECPPVGDPHTLSKMNTLSRC-PPSRPSKTISQEVR 280
+ P C D ++ N + PP PSK+ +E+R
Sbjct: 360 GRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKS-PEEMR 405
Score = 51.6 bits (118), Expect = 4e-06
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G ++ NP P P +++ KL IDK SRI FP+ F+ FN+ YWIIY
Sbjct: 384 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 438
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 140 bits (340), Expect = 6e-33
Identities = 79/210 (37%), Positives = 120/210 (57%), Gaps = 12/210 (5%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK------RIQMRKQRFVAIQKIASE 242
LPK+SYVK+ID+++ C + VFA+LLEYA V ++++ R++ R++R + + E
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRE 367
Query: 243 KKLPECPPVGDPHTLS-KMNTLSRCPPSRP 271
+ G H L K T + P+ P
Sbjct: 368 SRF-NFSGYGMGHCLQVKDGTAVKATPANP 396
Score = 43.2 bits (97), Expect = 0.002
Identities = 21/51 (41%), Positives = 24/51 (47%)
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
A NP P P G I K ID SR FP+ F+ FN+ YWI Y
Sbjct: 391 ATPANPLPQPPKDGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 140 bits (339), Expect = 7e-33
Identities = 68/160 (42%), Positives = 101/160 (63%), Gaps = 4/160 (2%)
Query: 68 VITLTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRL 125
++ L + GYTM D+ ++W +E P V V+ ++LPQF + + R TG ++ +
Sbjct: 186 IMQLESFGYTMNDLIFEWQDEAP--VQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCI 243
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG
Sbjct: 244 EVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGS 303
Query: 186 NAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++
Sbjct: 304 RASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 343
Score = 36.7 bits (81), Expect = 0.13
Identities = 13/24 (54%), Positives = 17/24 (70%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
ID SR FP+ F+ FN+ YW+IY
Sbjct: 413 IDTISRACFPLAFLIFNIFYWVIY 436
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 140 bits (339), Expect = 7e-33
Identities = 68/157 (43%), Positives = 101/157 (64%), Gaps = 4/157 (2%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
LPK+SYVK+ID+++ C + VFA+LLEYA V +++++
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 140 bits (339), Expect = 7e-33
Identities = 68/157 (43%), Positives = 101/157 (64%), Gaps = 4/157 (2%)
Query: 71 LTTVGYTMRDIRYKW-NEGPNSVGVSSEVSLPQFKVLGHRQRAMEIS-LTTGNYSRLACE 128
L + GYTM D+ ++W ++GP V V+ ++LPQF + ++ TG ++ + +
Sbjct: 190 LESFGYTMNDLIFEWLSDGP--VQVAEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVK 247
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+
Sbjct: 248 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 307
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
LPK+SYVK+ID+++ C + VFA+LLEYA V +++++
Sbjct: 308 LPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQ 344
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 140 bits (339), Expect = 7e-33
Identities = 65/159 (40%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Query: 68 VITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQ-RAMEISLTTGNYSRLA 126
++ L + GYTM D+ ++W E +V V+ ++LPQF + + R TG ++ +
Sbjct: 181 IMQLESFGYTMNDLIFEWQE-QGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGKFTCIE 239
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
R MGYYLIQ+YIPS LIVI+SW+SFW+N +A PARV LG
Sbjct: 240 ARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSR 299
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
A+LPK+SYVK+ID+++ C + VF++LLEYA V +++++
Sbjct: 300 ASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ 338
Score = 51.6 bits (118), Expect = 4e-06
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G ++ NP P P +++ KL IDK SRI FP+ F+ FN+ YWIIY
Sbjct: 392 GANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 137 bits (331), Expect = 7e-32
Identities = 86/294 (29%), Positives = 146/294 (49%), Gaps = 16/294 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLA 126
+ ++ GY ++ Y+W + NSV + + S L QF +G R ++ + G+Y +
Sbjct: 187 LIFSSYGYPKEEMIYRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MGY+ IQ YIP L V++SWVSFW+ ++ATPAR ALG
Sbjct: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK-RIQMRKQRFVAIQKIASEKKL 245
+LP++SYV ++D+++ CF+ VFA+L+EYAT+ Y + R ++ ++ S + +
Sbjct: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 364
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
PE + P S + L PP T++ V ++ + + L+
Sbjct: 365 PERISLQAP---SNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYE--CLDGKDCQSFFC 419
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
EE G + + ++D YSR+ FP F+ FNL+YW+ YL++
Sbjct: 420 CYEE------CKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 137 bits (331), Expect = 7e-32
Identities = 86/294 (29%), Positives = 146/294 (49%), Gaps = 16/294 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLA 126
+ ++ GY ++ Y+W + NSV + + S L QF +G R ++ + G+Y +
Sbjct: 169 LIFSSYGYPKEEMIYRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 226
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MGY+ IQ YIP L V++SWVSFW+ ++ATPAR ALG
Sbjct: 227 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 286
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK-RIQMRKQRFVAIQKIASEKKL 245
+LP++SYV ++D+++ CF+ VFA+L+EYAT+ Y + R ++ ++ S + +
Sbjct: 287 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 346
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
PE + P S + L PP T++ V ++ + + L+
Sbjct: 347 PERISLQAP---SNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYE--CLDGKDCQSFFC 401
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
EE G + + ++D YSR+ FP F+ FNL+YW+ YL++
Sbjct: 402 CYEE------CKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 449
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 136 bits (330), Expect = 9e-32
Identities = 86/294 (29%), Positives = 146/294 (49%), Gaps = 16/294 (5%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVS--LPQFKVLGHRQRAMEISLTTGNYSRLA 126
+ ++ GY ++ Y+W + NSV + + S L QF +G R ++ + G+Y +
Sbjct: 187 LIFSSYGYPKEEMIYRWRK--NSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
Query: 127 CEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXN 186
+ R MGY+ IQ YIP L V++SWVSFW+ ++ATPAR ALG
Sbjct: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
Query: 187 AALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAK-RIQMRKQRFVAIQKIASEKKL 245
+LP++SYV ++D+++ CF+ VFA+L+EYAT+ Y + R ++ ++ S + +
Sbjct: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 364
Query: 246 PECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGG 305
PE + P S + L PP T++ V ++ + + L+
Sbjct: 365 PERISLQAP---SNYSLLDMRPPPPAMITLNNSVYWQEFEDTCVYE--CLDGKDCQSFFC 419
Query: 306 ADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLHV 359
EE G + + ++D YSR+ FP F+ FNL+YW+ YL++
Sbjct: 420 CYEE------CKSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 136 bits (328), Expect = 2e-31
Identities = 85/285 (29%), Positives = 135/285 (47%), Gaps = 20/285 (7%)
Query: 76 YTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W G N SV V+ + S L Q+ +LGH I +TG Y + R
Sbjct: 214 YTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKR 273
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 274 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 333
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + + V + + +KK P P
Sbjct: 334 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVP-EALEMKKKTPAAPA--- 389
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
T + N + P ++++ F A + I + +++P
Sbjct: 390 KKTSTTFNIVGTTYPI----NLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTE 445
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ +SK +DK SRI+FPV F FNL+YW Y++
Sbjct: 446 TKTY--NSVSK--------VDKISRIIFPVLFAIFNLVYWATYVN 480
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 136 bits (328), Expect = 2e-31
Identities = 85/285 (29%), Positives = 135/285 (47%), Gaps = 20/285 (7%)
Query: 76 YTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W G N SV V+ + S L Q+ +LGH I +TG Y + R
Sbjct: 214 YTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKR 273
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 274 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 333
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + + V + + +KK P P
Sbjct: 334 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVP-EALEMKKKTPAAPA--- 389
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
T + N + P ++++ F A + I + +++P
Sbjct: 390 KKTSTTFNIVGTTYPI----NLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTE 445
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ +SK +DK SRI+FPV F FNL+YW Y++
Sbjct: 446 TKTY--NSVSK--------VDKISRIIFPVLFAIFNLVYWATYVN 480
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 136 bits (328), Expect = 2e-31
Identities = 85/285 (29%), Positives = 135/285 (47%), Gaps = 20/285 (7%)
Query: 76 YTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W G N SV V+ + S L Q+ +LGH I +TG Y + R
Sbjct: 214 YTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKR 273
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 274 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 333
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + + V + + +KK P P
Sbjct: 334 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVP-EALEMKKKTPAAPA--- 389
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPGP 313
T + N + P ++++ F A + I + +++P
Sbjct: 390 KKTSTTFNIVGTTYPI----NLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTE 445
Query: 314 HPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ +SK +DK SRI+FPV F FNL+YW Y++
Sbjct: 446 TKTY--NSVSK--------VDKISRIIFPVLFAIFNLVYWATYVN 480
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 132 bits (318), Expect = 3e-30
Identities = 95/311 (30%), Positives = 143/311 (45%), Gaps = 32/311 (10%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y +I Y W +GP SV V E S L Q+ ++G
Sbjct: 158 MRLVNFPMDGH---ACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQT 214
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQIY P + VI+S VSFW+N+ + PAR
Sbjct: 215 VSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTV 274
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY---MAKRI 226
G +LPK+SY ++D ++ CF VF++L+E+A V Y + +
Sbjct: 275 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQK 334
Query: 227 QMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP 286
RK +F A + K H SK + R ++S +
Sbjct: 335 AKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRI------TSLSLPIVSSSEAN 388
Query: 287 KAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFV 346
K ++ L++T P+ P +S G T S ID+YSRI+FPV F
Sbjct: 389 KVLTRAPILQST----------------PVTP-PPLSPAFGGT-SKIDQYSRILFPVAFA 430
Query: 347 CFNLMYWIIYL 357
FNL+YW++YL
Sbjct: 431 GFNLVYWVVYL 441
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 132 bits (318), Expect = 3e-30
Identities = 95/311 (30%), Positives = 143/311 (45%), Gaps = 32/311 (10%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y +I Y W +GP SV V E S L Q+ ++G
Sbjct: 158 MRLVNFPMDGH---ACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQT 214
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQIY P + VI+S VSFW+N+ + PAR
Sbjct: 215 VSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTV 274
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY---MAKRI 226
G +LPK+SY ++D ++ CF VF++L+E+A V Y + +
Sbjct: 275 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQK 334
Query: 227 QMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP 286
RK +F A + K H SK + R ++S +
Sbjct: 335 AKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRI------TSLSLPIVSSSEAN 388
Query: 287 KAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFV 346
K ++ L++T P+ P +S G T S ID+YSRI+FPV F
Sbjct: 389 KVLTRAPILQST----------------PVTP-PPLSPAFGGT-SKIDQYSRILFPVAFA 430
Query: 347 CFNLMYWIIYL 357
FNL+YW++YL
Sbjct: 431 GFNLVYWVVYL 441
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 132 bits (318), Expect = 3e-30
Identities = 95/311 (30%), Positives = 143/311 (45%), Gaps = 32/311 (10%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y +I Y W +GP SV V E S L Q+ ++G
Sbjct: 158 MRLVNFPMDGH---ACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQT 214
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQIY P + VI+S VSFW+N+ + PAR
Sbjct: 215 VSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTV 274
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY---MAKRI 226
G +LPK+SY ++D ++ CF VF++L+E+A V Y + +
Sbjct: 275 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQK 334
Query: 227 QMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP 286
RK +F A + K H SK + R ++S +
Sbjct: 335 AKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRI------TSLSLPIVSSSEAN 388
Query: 287 KAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFV 346
K ++ L++T P+ P +S G T S ID+YSRI+FPV F
Sbjct: 389 KVLTRAPILQST----------------PVTP-PPLSPAFGGT-SKIDQYSRILFPVAFA 430
Query: 347 CFNLMYWIIYL 357
FNL+YW++YL
Sbjct: 431 GFNLVYWVVYL 441
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 132 bits (318), Expect = 3e-30
Identities = 95/311 (30%), Positives = 143/311 (45%), Gaps = 32/311 (10%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y +I Y W +GP SV V E S L Q+ ++G
Sbjct: 158 MRLVNFPMDGH---ACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQT 214
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQIY P + VI+S VSFW+N+ + PAR
Sbjct: 215 VSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTV 274
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY---MAKRI 226
G +LPK+SY ++D ++ CF VF++L+E+A V Y + +
Sbjct: 275 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQK 334
Query: 227 QMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP 286
RK +F A + K H SK + R ++S +
Sbjct: 335 AKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRI------TSLSLPIVSSSEAN 388
Query: 287 KAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFV 346
K ++ L++T P+ P +S G T S ID+YSRI+FPV F
Sbjct: 389 KVLTRAPILQST----------------PVTP-PPLSPAFGGT-SKIDQYSRILFPVAFA 430
Query: 347 CFNLMYWIIYL 357
FNL+YW++YL
Sbjct: 431 GFNLVYWVVYL 441
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 130 bits (314), Expect = 8e-30
Identities = 95/311 (30%), Positives = 142/311 (45%), Gaps = 32/311 (10%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y +I Y W +GP SV V E S L Q+ ++G
Sbjct: 158 MRLVNFPMDGH---ACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQT 214
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQIY P + VI+S VSFW+N+ + PAR
Sbjct: 215 VSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTV 274
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGY---MAKRI 226
G +LPK+SY ++D ++ CF VF++L+E+A V Y + +
Sbjct: 275 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQK 334
Query: 227 QMRKQRFVAIQKIASEKKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP 286
RK +F A + K H SK + R ++S +
Sbjct: 335 AKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRI------TSLSLPIVSSSEAN 388
Query: 287 KAHSKGGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFV 346
K ++ L++T P P+ P G T S ID+YSRI+FPV F
Sbjct: 389 KVLTRAPILQST-----------PVTPPPLPPA------FGGT-SKIDQYSRILFPVAFA 430
Query: 347 CFNLMYWIIYL 357
FNL+YW++YL
Sbjct: 431 GFNLVYWVVYL 441
>U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta
subunit protein.
Length = 497
Score = 130 bits (313), Expect = 1e-29
Identities = 96/306 (31%), Positives = 148/306 (48%), Gaps = 28/306 (9%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLAC 127
L + GYT D+R+ W G + V + +++LPQF + + TG Y+ +
Sbjct: 201 LESFGYTTDDLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R +G+Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQ----KIA 240
LPK+SYVK++DV+L C + FASL+EYA V M KR++ K R + K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 241 SEKKLPECPPVGDPHTLSKMNT-LSRCPPSRPSKTISQEVRFKVHD--PKAHS------K 291
+ K G P +S + +RC SK+ + F + P+
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 292 GGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLM 351
G +E +N G G + +N P P K + + ID Y+R +FP CF+ FN++
Sbjct: 439 GKPIE--VNNGLGKSQAKNNKKPP--PAKPV---IPTAAKRIDLYARALFPFCFLFFNVI 491
Query: 352 YWIIYL 357
YW IYL
Sbjct: 492 YWSIYL 497
>BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta
protein.
Length = 497
Score = 130 bits (313), Expect = 1e-29
Identities = 96/306 (31%), Positives = 148/306 (48%), Gaps = 28/306 (9%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLAC 127
L + GYT D+R+ W G + V + +++LPQF + + TG Y+ +
Sbjct: 201 LESFGYTTDDLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R +G+Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQ----KIA 240
LPK+SYVK++DV+L C + FASL+EYA V M KR++ K R + K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 241 SEKKLPECPPVGDPHTLSKMNT-LSRCPPSRPSKTISQEVRFKVHD--PKAHS------K 291
+ K G P +S + +RC SK+ + F + P+
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 292 GGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLM 351
G +E +N G G + +N P P K + + ID Y+R +FP CF+ FN++
Sbjct: 439 GKPIE--VNNGLGKSQAKNNKKPP--PAKPV---IPTAAKRIDLYARALFPFCFLFFNVI 491
Query: 352 YWIIYL 357
YW IYL
Sbjct: 492 YWSIYL 497
>AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 130 bits (313), Expect = 1e-29
Identities = 96/306 (31%), Positives = 148/306 (48%), Gaps = 28/306 (9%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLAC 127
L + GYT D+R+ W G + V + +++LPQF + + TG Y+ +
Sbjct: 201 LESFGYTTDDLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R +G+Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQ----KIA 240
LPK+SYVK++DV+L C + FASL+EYA V M KR++ K R + K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 241 SEKKLPECPPVGDPHTLSKMNT-LSRCPPSRPSKTISQEVRFKVHD--PKAHS------K 291
+ K G P +S + +RC SK+ + F + P+
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 292 GGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLM 351
G +E +N G G + +N P P K + + ID Y+R +FP CF+ FN++
Sbjct: 439 GKPIE--VNNGLGKSQAKNNKKPP--PAKPV---IPTAAKRIDLYARALFPFCFLFFNVI 491
Query: 352 YWIIYL 357
YW IYL
Sbjct: 492 YWSIYL 497
>AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 130 bits (313), Expect = 1e-29
Identities = 96/306 (31%), Positives = 148/306 (48%), Gaps = 28/306 (9%)
Query: 71 LTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHR---QRAMEISLTTGNYSRLAC 127
L + GYT D+R+ W G + V + +++LPQF + + TG Y+ +
Sbjct: 201 LESFGYTTDDLRFIWQSG-DPVQLE-KIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEV 258
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R +G+Y++ +Y P+ LIV++SW+SFW+N +A+ ARV LG A
Sbjct: 259 IFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAA 318
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM---AKRIQMRKQRFVAIQ----KIA 240
LPK+SYVK++DV+L C + FASL+EYA V M KR++ K R + K
Sbjct: 319 ELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGG 378
Query: 241 SEKKLPECPPVGDPHTLSKMNT-LSRCPPSRPSKTISQEVRFKVHD--PKAHS------K 291
+ K G P +S + +RC SK+ + F + P+
Sbjct: 379 NVAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCY 438
Query: 292 GGTLENTINGGRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLM 351
G +E +N G G + +N P P K + + ID Y+R +FP CF+ FN++
Sbjct: 439 GKPIE--VNNGLGKSQAKNNKKPP--PAKPV---IPTAAKRIDLYARALFPFCFLFFNVI 491
Query: 352 YWIIYL 357
YW IYL
Sbjct: 492 YWSIYL 497
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 128 bits (310), Expect = 2e-29
Identities = 57/164 (34%), Positives = 90/164 (54%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I Y+W VG + L QF +G R + T+G+Y ++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP LIV++SWVSFW+N++A PAR +LG +
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LPK+SYV ++D+++ CF+ VF++L+EY T+ Y + K +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
Score = 40.3 bits (90), Expect = 0.011
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D Y+RI FP F FNL+YW+ YL++
Sbjct: 441 MDSYARIFFPTAFCLFNLVYWVSYLYL 467
Score = 33.5 bits (73), Expect = 1.2
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
GY +I Y WK VG + +L QF +G R V+ T+ Y + + +
Sbjct: 212 GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYF 266
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 128 bits (310), Expect = 2e-29
Identities = 57/164 (34%), Positives = 90/164 (54%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I Y+W VG + L QF +G R + T+G+Y ++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP LIV++SWVSFW+N++A PAR +LG +
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LPK+SYV ++D+++ CF+ VF++L+EY T+ Y + K +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
Score = 40.3 bits (90), Expect = 0.011
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D Y+RI FP F FNL+YW+ YL++
Sbjct: 441 MDSYARIFFPTAFCLFNLVYWVSYLYL 467
Score = 33.5 bits (73), Expect = 1.2
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
GY +I Y WK VG + +L QF +G R V+ T+ Y + + +
Sbjct: 212 GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYF 266
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 128 bits (310), Expect = 2e-29
Identities = 57/164 (34%), Positives = 90/164 (54%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I Y+W VG + L QF +G R + T+G+Y ++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP LIV++SWVSFW+N++A PAR +LG +
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LPK+SYV ++D+++ CF+ VF++L+EY T+ Y + K +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
Score = 40.3 bits (90), Expect = 0.011
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D Y+RI FP F FNL+YW+ YL++
Sbjct: 441 MDSYARIFFPTAFCLFNLVYWVSYLYL 467
Score = 33.5 bits (73), Expect = 1.2
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
GY +I Y WK VG + +L QF +G R V+ T+ Y + + +
Sbjct: 212 GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYF 266
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 128 bits (310), Expect = 2e-29
Identities = 57/164 (34%), Positives = 90/164 (54%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I Y+W VG + L QF +G R + T+G+Y ++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP LIV++SWVSFW+N++A PAR +LG +
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LPK+SYV ++D+++ CF+ VF++L+EY T+ Y + K +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLRYFVSNRKPSKDK 369
Score = 40.3 bits (90), Expect = 0.011
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D Y+RI FP F FNL+YW+ YL++
Sbjct: 449 MDSYARIFFPTAFCLFNLVYWVSYLYL 475
Score = 33.5 bits (73), Expect = 1.2
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
GY +I Y WK VG + +L QF +G R V+ T+ Y + + +
Sbjct: 212 GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYF 266
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 128 bits (310), Expect = 2e-29
Identities = 57/164 (34%), Positives = 90/164 (54%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I Y+W VG + L QF +G R + T+G+Y ++
Sbjct: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP LIV++SWVSFW+N++A PAR +LG +
Sbjct: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LPK+SYV ++D+++ CF+ VF++L+EY T+ Y + K +
Sbjct: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
Score = 40.3 bits (90), Expect = 0.011
Identities = 14/27 (51%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D Y+RI FP F FNL+YW+ YL++
Sbjct: 441 MDSYARIFFPTAFCLFNLVYWVSYLYL 467
Score = 33.5 bits (73), Expect = 1.2
Identities = 16/55 (29%), Positives = 25/55 (45%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRY 83
GY +I Y WK VG + +L QF +G R V+ T+ Y + + +
Sbjct: 212 GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYF 266
>M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid
receptor type A rho-1 subunit protein.
Length = 473
Score = 127 bits (307), Expect = 5e-29
Identities = 65/183 (35%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ + + YT D+ W +G +S+ +SL QF + H + +TG Y+RL
Sbjct: 208 LEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYI 267
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV LG NA
Sbjct: 268 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNA 327
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SY+K++D+YL FV VF S+LEYA V Y+ +Q RK++ + +K+ LP
Sbjct: 328 SMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKEQKLR-EKLPCTSGLP- 384
Query: 248 CPP 250
PP
Sbjct: 385 -PP 386
Score = 42.7 bits (96), Expect = 0.002
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSRI+FP ++ FNL+YW I+
Sbjct: 449 IDKYSRIIFPAAYILFNLIYWSIF 472
>BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 474
Score = 127 bits (307), Expect = 5e-29
Identities = 65/183 (35%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ + + YT D+ W +G +S+ +SL QF + H + +TG Y+RL
Sbjct: 209 LEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYI 268
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV LG NA
Sbjct: 269 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNA 328
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SY+K++D+YL FV VF S+LEYA V Y+ +Q RK++ + +K+ LP
Sbjct: 329 SMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKEQKLR-EKLPCTSGLP- 385
Query: 248 CPP 250
PP
Sbjct: 386 -PP 387
Score = 42.7 bits (96), Expect = 0.002
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSRI+FP ++ FNL+YW I+
Sbjct: 450 IDKYSRIIFPAAYILFNLIYWSIF 473
>AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 127 bits (307), Expect = 5e-29
Identities = 65/183 (35%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ + + YT D+ W +G +S+ +SL QF + H + +TG Y+RL
Sbjct: 208 LEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYI 267
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV LG NA
Sbjct: 268 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNA 327
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SY+K++D+YL FV VF S+LEYA V Y+ +Q RK++ + +K+ LP
Sbjct: 328 SMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKEQKLR-EKLPCTSGLP- 384
Query: 248 CPP 250
PP
Sbjct: 385 -PP 386
Score = 42.7 bits (96), Expect = 0.002
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSRI+FP ++ FNL+YW I+
Sbjct: 449 IDKYSRIIFPAAYILFNLIYWSIF 472
>AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 127 bits (307), Expect = 5e-29
Identities = 65/183 (35%), Positives = 103/183 (56%), Gaps = 5/183 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLG-HRQRAMEISLTTGNYSRLAC 127
+ + + YT D+ W +G +S+ +SL QF + H + +TG Y+RL
Sbjct: 208 LEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTTTKLAFYSSTGWYNRLYI 267
Query: 128 EIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNA 187
R + ++L+Q Y P+ L+V++SWVSFW++R A PARV LG NA
Sbjct: 268 NFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTMSTIITGVNA 327
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPE 247
++P++SY+K++D+YL FV VF S+LEYA V Y+ +Q RK++ + +K+ LP
Sbjct: 328 SMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLT-TVQERKEQKLR-EKLPCTSGLP- 384
Query: 248 CPP 250
PP
Sbjct: 385 -PP 386
Score = 42.7 bits (96), Expect = 0.002
Identities = 15/24 (62%), Positives = 20/24 (83%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIY 356
IDKYSRI+FP ++ FNL+YW I+
Sbjct: 449 IDKYSRIIFPAAYILFNLIYWSIF 472
>X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1
subunit protein.
Length = 456
Score = 125 bits (302), Expect = 2e-28
Identities = 92/287 (32%), Positives = 135/287 (47%), Gaps = 35/287 (12%)
Query: 76 YTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y+W P SV V+ + S L Q+ +LG + + +TG Y + R
Sbjct: 189 YTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKR 248
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 249 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + V +K KK V D
Sbjct: 309 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEK---PKK------VKD 359
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP--KAHSKGGTLENTINGGRGGADEENP 311
P + K NT + P+ T S DP +K T+E E P
Sbjct: 360 P-LIKKNNTYA------PTAT-SYTPNLARGDPGLATIAKSATIE---------PKEVKP 402
Query: 312 GPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
P P K + + S ID+ SRI FP+ F FNL+YW YL+
Sbjct: 403 ETKPPEPKKTFNSV-----SKIDRLSRIAFPLLFGIFNLVYWATYLN 444
>BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein.
Length = 456
Score = 125 bits (302), Expect = 2e-28
Identities = 92/287 (32%), Positives = 135/287 (47%), Gaps = 35/287 (12%)
Query: 76 YTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y+W P SV V+ + S L Q+ +LG + + +TG Y + R
Sbjct: 189 YTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKR 248
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 249 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + V +K KK V D
Sbjct: 309 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEK---PKK------VKD 359
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP--KAHSKGGTLENTINGGRGGADEENP 311
P + K NT + P+ T S DP +K T+E E P
Sbjct: 360 P-LIKKNNTYA------PTAT-SYTPNLARGDPGLATIAKSATIE---------PKEVKP 402
Query: 312 GPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
P P K + + S ID+ SRI FP+ F FNL+YW YL+
Sbjct: 403 ETKPPEPKKTFNSV-----SKIDRLSRIAFPLLFGIFNLVYWATYLN 444
>AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 1 precursor variant protein.
Length = 456
Score = 125 bits (302), Expect = 2e-28
Identities = 92/287 (32%), Positives = 135/287 (47%), Gaps = 35/287 (12%)
Query: 76 YTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y+W P SV V+ + S L Q+ +LG + + +TG Y + R
Sbjct: 189 YTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKR 248
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 249 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVGD 253
Y ++D ++ C+ VF++L+E+ATV Y KR + V +K KK V D
Sbjct: 309 YATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEK---PKK------VKD 359
Query: 254 PHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDP--KAHSKGGTLENTINGGRGGADEENP 311
P + K NT + P+ T S DP +K T+E E P
Sbjct: 360 P-LIKKNNTYA------PTAT-SYTPNLARGDPGLATIAKSATIE---------PKEVKP 402
Query: 312 GPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
P P K + + S ID+ SRI FP+ F FNL+YW YL+
Sbjct: 403 ETKPPEPKKTFNSV-----SKIDRLSRIAFPLLFGIFNLVYWATYLN 444
>AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 219
Score = 124 bits (300), Expect = 4e-28
Identities = 81/228 (35%), Positives = 114/228 (50%), Gaps = 31/228 (13%)
Query: 133 RSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKI 192
R MGYYLIQ+YIPS LIVI+SWVSFW+N +A PARVALG A+LPK+
Sbjct: 6 RQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKV 65
Query: 193 SYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPECPPVG 252
SYVK+ID+++ C + VF++LLEYA V +++++ RF +K +E
Sbjct: 66 SYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQ-HKELLRFRRKRKNKTEA--------- 115
Query: 253 DPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGGRGGADEENPG 312
L K S + EVR A+ G L+ + G + P
Sbjct: 116 --FALEKFYRFS---------DMDDEVRESRFSFTAYGMGPCLQ-----AKDGMTPKGPN 159
Query: 313 PHPIH----PGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
HP+ ++ K+ ID SR FP+ F+ FN+ YW+IY
Sbjct: 160 -HPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIY 206
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 124 bits (299), Expect = 5e-28
Identities = 56/159 (35%), Positives = 90/159 (56%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
++A + + + GYT+ DI W++ N++ ++ E+ +PQF LG + E+ TG+Y
Sbjct: 194 KQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYI 253
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
RL + Q R + YL+Q+Y P+ L I SW+SFW+N +++ ARV +G
Sbjct: 254 RLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDS 313
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
LP IS +K+ID+Y+ C VF SLLEY + Y+
Sbjct: 314 HLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYL 352
Score = 38.7 bits (86), Expect = 0.033
Identities = 18/63 (28%), Positives = 31/63 (49%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEG 88
GYT+ DI W D +++ M+ E+ +PQF LG + + T Y ++++
Sbjct: 205 GYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQRE 264
Query: 89 PNS 91
NS
Sbjct: 265 VNS 267
Score = 37.5 bits (83), Expect = 0.076
Identities = 11/26 (42%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+DK+SR +FP+ F FN++YW+ +++
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYWVYHMY 632
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 124 bits (299), Expect = 5e-28
Identities = 56/159 (35%), Positives = 90/159 (56%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
++A + + + GYT+ DI W++ N++ ++ E+ +PQF LG + E+ TG+Y
Sbjct: 194 KQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYI 253
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
RL + Q R + YL+Q+Y P+ L I SW+SFW+N +++ ARV +G
Sbjct: 254 RLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDS 313
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
LP IS +K+ID+Y+ C VF SLLEY + Y+
Sbjct: 314 HLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYL 352
Score = 38.7 bits (86), Expect = 0.033
Identities = 18/63 (28%), Positives = 31/63 (49%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEG 88
GYT+ DI W D +++ M+ E+ +PQF LG + + T Y ++++
Sbjct: 205 GYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQRE 264
Query: 89 PNS 91
NS
Sbjct: 265 VNS 267
Score = 37.5 bits (83), Expect = 0.076
Identities = 11/26 (42%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+DK+SR +FP+ F FN++YW+ +++
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYWVYHMY 632
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 124 bits (299), Expect = 5e-28
Identities = 80/295 (27%), Positives = 137/295 (46%), Gaps = 21/295 (7%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNY 122
++ ++ L + GY+ DI Y W+E + ++ L QF + +R ++ + G +
Sbjct: 175 EQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQF 234
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
RL+ R+ G Y+IQ Y+PS L+V +SWVSFW+++ A PARV+LG
Sbjct: 235 PRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLM 294
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
++LP+ S +K++DVY C+V VFA+L+EYA + A + +K + V + + +E
Sbjct: 295 VSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK-VKVSRPRAE 353
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTI-NG 301
+ + +LS SR + + + + E +G
Sbjct: 354 MDVRNAIVL---FSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSG 410
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G+GG ++L + ID Y+R VFP F N++YW Y
Sbjct: 411 GQGGIR---------------ARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
Score = 32.3 bits (70), Expect = 2.9
Identities = 12/47 (25%), Positives = 24/47 (51%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVG 75
GY+ DI Y+W + + +++QL QF + +R ++ + G
Sbjct: 186 GYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAG 232
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 124 bits (299), Expect = 5e-28
Identities = 80/295 (27%), Positives = 137/295 (46%), Gaps = 21/295 (7%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNY 122
++ ++ L + GY+ DI Y W+E + ++ L QF + +R ++ + G +
Sbjct: 175 EQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQF 234
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
RL+ R+ G Y+IQ Y+PS L+V +SWVSFW+++ A PARV+LG
Sbjct: 235 PRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLM 294
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
++LP+ S +K++DVY C+V VFA+L+EYA + A + +K + V + + +E
Sbjct: 295 VSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK-VKVSRPRAE 353
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTI-NG 301
+ + +LS SR + + + + E +G
Sbjct: 354 MDVRNAIVL---FSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSG 410
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G+GG ++L + ID Y+R VFP F N++YW Y
Sbjct: 411 GQGGIR---------------ARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
Score = 32.3 bits (70), Expect = 2.9
Identities = 12/47 (25%), Positives = 24/47 (51%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVG 75
GY+ DI Y+W + + +++QL QF + +R ++ + G
Sbjct: 186 GYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAG 232
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 124 bits (299), Expect = 5e-28
Identities = 56/159 (35%), Positives = 90/159 (56%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
++A + + + GYT+ DI W++ N++ ++ E+ +PQF LG + E+ TG+Y
Sbjct: 194 KQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYI 253
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
RL + Q R + YL+Q+Y P+ L I SW+SFW+N +++ ARV +G
Sbjct: 254 RLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDS 313
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
LP IS +K+ID+Y+ C VF SLLEY + Y+
Sbjct: 314 HLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYL 352
Score = 38.7 bits (86), Expect = 0.033
Identities = 18/63 (28%), Positives = 31/63 (49%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEG 88
GYT+ DI W D +++ M+ E+ +PQF LG + + T Y ++++
Sbjct: 205 GYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQRE 264
Query: 89 PNS 91
NS
Sbjct: 265 VNS 267
Score = 37.5 bits (83), Expect = 0.076
Identities = 11/26 (42%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+DK+SR +FP+ F FN++YW+ +++
Sbjct: 607 VDKWSRFLFPLAFGLFNIVYWVYHMY 632
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 124 bits (299), Expect = 5e-28
Identities = 56/159 (35%), Positives = 90/159 (56%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYS 123
++A + + + GYT+ DI W++ N++ ++ E+ +PQF LG + E+ TG+Y
Sbjct: 189 KQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYI 248
Query: 124 RLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXX 183
RL + Q R + YL+Q+Y P+ L I SW+SFW+N +++ ARV +G
Sbjct: 249 RLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTTIDS 308
Query: 184 XXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
LP IS +K+ID+Y+ C VF SLLEY + Y+
Sbjct: 309 HLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYL 347
Score = 38.7 bits (86), Expect = 0.033
Identities = 18/63 (28%), Positives = 31/63 (49%)
Query: 29 GYTMRDIRYHWKDGHSSVGMSNEVQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEG 88
GYT+ DI W D +++ M+ E+ +PQF LG + + T Y ++++
Sbjct: 200 GYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYTGSYIRLILKFQVQRE 259
Query: 89 PNS 91
NS
Sbjct: 260 VNS 262
Score = 37.5 bits (83), Expect = 0.076
Identities = 11/26 (42%), Positives = 21/26 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLH 358
+DK+SR +FP+ F FN++YW+ +++
Sbjct: 602 VDKWSRFLFPLAFGLFNIVYWVYHMY 627
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 122 bits (294), Expect = 2e-27
Identities = 79/295 (26%), Positives = 136/295 (46%), Gaps = 21/295 (7%)
Query: 64 QRATVITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISL-TTGNY 122
++ ++ L + GY+ DI Y W+E + ++ L QF + + ++ + G +
Sbjct: 175 EQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYHFTTELMNFKSAGQF 234
Query: 123 SRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXX 182
RL+ R+ G Y+IQ Y+PS L+V +SWVSFW+++ A PARV+LG
Sbjct: 235 PRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLM 294
Query: 183 XXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASE 242
++LP+ S +K++DVY C+V VFA+L+EYA + A + +K + V + + +E
Sbjct: 295 VSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAK-VKVSRPRAE 353
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTI-NG 301
+ + +LS SR + + + + E +G
Sbjct: 354 MDVRNAIVL---FSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSG 410
Query: 302 GRGGADEENPGPHPIHPGKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIY 356
G+GG ++L + ID Y+R VFP F N++YW Y
Sbjct: 411 GQGGIR---------------ARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 120 bits (289), Expect = 8e-27
Identities = 65/196 (33%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ ++ GY +I YKW + V L QF +G R +G+Y +
Sbjct: 204 LEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIF 263
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R MGY+ IQ YIP L V++SWVSFW+N++A PAR +LG +
Sbjct: 264 FDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 323
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQRFVAIQKIASEKKLPEC 248
LPK+SYV ++D+++ CF+ VFA+L+EY T+ Y Q K A + + K
Sbjct: 324 LPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN-QKGK---TATKDRKLKNKASMT 379
Query: 249 PPVGDPHTLSKMNTLS 264
P + TL MN +S
Sbjct: 380 PGLHPGSTLIPMNNIS 395
Score = 42.3 bits (95), Expect = 0.003
Identities = 16/27 (59%), Positives = 20/27 (74%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
ID YSRI FP F FNL+YW+ YL++
Sbjct: 439 IDSYSRIFFPTAFALFNLVYWVGYLYL 465
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 114 bits (275), Expect = 4e-25
Identities = 53/165 (32%), Positives = 88/165 (53%), Gaps = 1/165 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
+ L + GY D+ + W G +SV + L Q+ + + TGNY+RL +
Sbjct: 176 LQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQQETGNYTRLVLQ 235
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
+ R++ Y++++ Y+PS +V++SWVSFW++ ++ PAR +G +
Sbjct: 236 FELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTLMIGSRTS 295
Query: 189 LPKIS-YVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 232
LP + ++K+IDVYLG CF VF +LLEYA Y + + K R
Sbjct: 296 LPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
Score = 39.5 bits (88), Expect = 0.019
Identities = 13/40 (32%), Positives = 25/40 (62%)
Query: 319 GKDISKLLGMTPSDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
G+ + PS++D YS+++FP+ F+ N+ YW Y++
Sbjct: 400 GRIVDYFTIQNPSNVDHYSKLLFPLIFMLANVFYWAYYMY 439
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 113 bits (273), Expect = 7e-25
Identities = 62/183 (33%), Positives = 94/183 (51%), Gaps = 6/183 (3%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y ++ Y W +GP SV V E S L Q+ ++G
Sbjct: 174 MRLVDFPMDGH---ACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQT 230
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQ YIP + VI+S VSFW+N+ + PAR
Sbjct: 231 VSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTV 290
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
G +LPK+SY+ ++D ++ CF VF++L+E+A V Y IQM
Sbjct: 291 FGITTVLTMTTLSISARHSLPKVSYLTAMDWFIAVCFAFVFSALIEFAAVNYFT-NIQME 349
Query: 230 KQR 232
K +
Sbjct: 350 KAK 352
Score = 47.2 bits (107), Expect = 9e-05
Identities = 18/31 (58%), Positives = 24/31 (77%)
Query: 327 GMTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
G S IDKY+RI+FPV F FN++YW++YL
Sbjct: 512 GSGTSKIDKYARILFPVTFGAFNMVYWVVYL 542
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 113 bits (272), Expect = 1e-24
Identities = 62/183 (33%), Positives = 93/183 (50%), Gaps = 6/183 (3%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
++L F + GH A + + Y ++ Y W +GP SV V E S L Q+ ++G
Sbjct: 174 MRLVDFPMDGH---ACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQT 230
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
+ I TG Y + R MGY++IQ YIP + VI+S VSFW+N+ + PAR
Sbjct: 231 VSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTV 290
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMR 229
G +LPK+SY ++D ++ CF VF++L+E+A V Y IQM
Sbjct: 291 FGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFT-NIQME 349
Query: 230 KQR 232
K +
Sbjct: 350 KAK 352
Score = 47.2 bits (107), Expect = 9e-05
Identities = 18/31 (58%), Positives = 24/31 (77%)
Query: 327 GMTPSDIDKYSRIVFPVCFVCFNLMYWIIYL 357
G S IDKY+RI+FPV F FN++YW++YL
Sbjct: 512 GSGTSKIDKYARILFPVTFGAFNMVYWVVYL 542
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 112 bits (270), Expect = 2e-24
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 5/176 (2%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y ++ Y W G SV V+ + S L Q+ ++G
Sbjct: 175 MQLEDFPMDAH---ACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
IS +TG Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 232 VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTV 291
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 292 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 347
Score = 44.4 bits (100), Expect = 7e-04
Identities = 20/33 (60%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S IDK SRIVFPV F FNL+YW YL+ V+
Sbjct: 423 SKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 112 bits (270), Expect = 2e-24
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 5/176 (2%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y ++ Y W G SV V+ + S L Q+ ++G
Sbjct: 175 MQLEDFPMDAH---ACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
IS +TG Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 232 VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTV 291
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 292 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 347
Score = 44.4 bits (100), Expect = 7e-04
Identities = 20/33 (60%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S IDK SRIVFPV F FNL+YW YL+ V+
Sbjct: 423 SKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 112 bits (270), Expect = 2e-24
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 5/176 (2%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y ++ Y W G SV V+ + S L Q+ ++G
Sbjct: 175 MQLEDFPMDAH---ACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
IS +TG Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 232 VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTV 291
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 292 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 347
Score = 44.4 bits (100), Expect = 7e-04
Identities = 20/33 (60%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S IDK SRIVFPV F FNL+YW YL+ V+
Sbjct: 423 SKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 112 bits (270), Expect = 2e-24
Identities = 58/176 (32%), Positives = 91/176 (51%), Gaps = 5/176 (2%)
Query: 52 VQLPQFRVLGHRQRATVITLTTVGYTMRDIRYKWNEGPN-SVGVSSEVS-LPQFKVLGHR 109
+QL F + H A + + Y ++ Y W G SV V+ + S L Q+ ++G
Sbjct: 175 MQLEDFPMDAH---ACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQT 231
Query: 110 QRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVA 169
IS +TG Y+ + R +GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 232 VGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTV 291
Query: 170 LGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
G +LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 292 FGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 347
Score = 44.4 bits (100), Expect = 7e-04
Identities = 20/33 (60%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S IDK SRIVFPV F FNL+YW YL+ V+
Sbjct: 423 SKIDKMSRIVFPVLFGTFNLVYWATYLNREPVI 455
>S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA
receptor alpha 2 subunit protein.
Length = 451
Score = 110 bits (264), Expect = 9e-24
Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Query: 76 YTMRDIRYKWN-EGPNSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W +SV V+ + S L Q+ +LG I +TG Y+ + R
Sbjct: 189 YTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKR 248
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 249 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 309 YATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/33 (57%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S ID+ SRIVFPV F FNL+YW YL+ V+
Sbjct: 415 SKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 447
>BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein.
Length = 367
Score = 110 bits (264), Expect = 9e-24
Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Query: 76 YTMRDIRYKWN-EGPNSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W +SV V+ + S L Q+ +LG I +TG Y+ + R
Sbjct: 189 YTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKR 248
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 249 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 309 YATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
>AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid A
receptor, alpha 2 precursor variant protein.
Length = 461
Score = 110 bits (264), Expect = 9e-24
Identities = 53/152 (34%), Positives = 82/152 (53%), Gaps = 2/152 (1%)
Query: 76 YTMRDIRYKWN-EGPNSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W +SV V+ + S L Q+ +LG I +TG Y+ + R
Sbjct: 199 YTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKR 258
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 259 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 318
Query: 194 YVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 319 YATAMDWFIAVCYAFVFSALIEFATVNYFTKR 350
Score = 42.3 bits (95), Expect = 0.003
Identities = 19/33 (57%), Positives = 23/33 (69%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLHVSDVV 363
S ID+ SRIVFPV F FNL+YW YL+ V+
Sbjct: 425 SKIDRMSRIVFPVLFGTFNLVYWATYLNREPVL 457
>X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for
gamma-aminobutyric-acid receptor alpha-subunit (GABA-A
receptor alpha-subunit). ).
Length = 354
Score = 106 bits (254), Expect = 1e-22
Identities = 53/154 (34%), Positives = 84/154 (54%), Gaps = 4/154 (2%)
Query: 76 YTMRDIRYKWNEGP-NSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y+W P +SV V+ + S L Q+ +LG + + +TG Y + R
Sbjct: 176 YTRAEVVYEWTREPAHSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKR 235
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAALPKIS 193
+GY++IQ Y+P + VI+S VSFWLNR + PAR G +LPK++
Sbjct: 236 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 295
Query: 194 YVKSI--DVYLGTCFVMVFASLLEYATVGYMAKR 225
Y ++ D ++ C+ VF++L+E+ATV Y KR
Sbjct: 296 YATAMDWDWFIAVCYAFVFSALIEFATVNYFTKR 329
>Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chloride
channel protein.
Length = 505
Score = 95.5 bits (227), Expect = 3e-19
Identities = 43/154 (27%), Positives = 73/154 (47%), Gaps = 1/154 (0%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + EI T G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKT-EIITTPGDFMVMTIF 269
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 270 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 329
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 330 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 363
Score = 41.1 bits (92), Expect = 0.006
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW++ L++
Sbjct: 479 LDNYSRVVFPVTFFFFNVLYWLVCLNL 505
>Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon
subunit protein.
Length = 506
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Score = 41.1 bits (92), Expect = 0.006
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW++ L++
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLNL 506
>U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Score = 41.1 bits (92), Expect = 0.006
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW++ L++
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLNL 506
>U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Score = 41.1 bits (92), Expect = 0.006
Identities = 14/27 (51%), Positives = 22/27 (81%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW++ L++
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCLNL 506
>BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 95.1 bits (226), Expect = 4e-19
Identities = 41/154 (26%), Positives = 72/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L QF G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein.
Length = 506
Score = 92.7 bits (220), Expect = 2e-18
Identities = 40/154 (25%), Positives = 71/154 (46%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTGNYSRLACE 128
++ ++ Y ++ YKW + + L Q G + I+ G++ +
Sbjct: 211 LSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQLDFTGVSNKTEIITTPVGDFMVMTIF 270
Query: 129 IQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXXNAA 188
R GY Q Y+PS + ++SWVSFW+ + PAR +LG
Sbjct: 271 FNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTFSRKN 330
Query: 189 LPKISYVKSIDVYLGTCFVMVFASLLEYATVGYM 222
P++SY+ ++D Y+ CFV F +LLE+A + ++
Sbjct: 331 FPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Score = 39.9 bits (89), Expect = 0.014
Identities = 14/27 (51%), Positives = 21/27 (77%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYLHV 359
+D YSR+VFPV F FN++YW+ L++
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLFCLNL 506
>AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein.
Length = 222
Score = 68.9 bits (161), Expect = 3e-11
Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 76 YTMRDIRYKWN-EGPNSVGVSSEVS-LPQFKVLGHRQRAMEISLTTGNYSRLACEIQFVR 133
YT ++ Y W +SV V+ + S L Q+ +LG I +TG Y+ + R
Sbjct: 126 YTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAHFHLKR 185
Query: 134 SMGYYLIQIYIPSGLIVIISWVSFWLNRNATPAR 167
+GY++IQ Y+P + VI+S VSFWLNR + PAR
Sbjct: 186 KIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 219
>AF228449-1|AAF62510.1| 70|Homo sapiens gamma-aminobutyric acid
receptor alpha 5 subunit protein.
Length = 70
Score = 46.4 bits (105), Expect = 2e-04
Identities = 16/38 (42%), Positives = 28/38 (73%)
Query: 188 ALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKR 225
+LPK++Y ++D ++ C+ VF++L+E+ATV Y KR
Sbjct: 17 SLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 54
>AK127001-1|BAC86784.1| 133|Homo sapiens protein ( Homo sapiens
cDNA FLJ45056 fis, clone BRAWH3023156, highly similar
to Gamma-aminobutyric-acid receptor beta-1 subunit
precursor. ).
Length = 133
Score = 41.9 bits (94), Expect = 0.004
Identities = 14/28 (50%), Positives = 22/28 (78%)
Query: 331 SDIDKYSRIVFPVCFVCFNLMYWIIYLH 358
+ IDK+SR+ FP+ F FN++YW+ Y+H
Sbjct: 106 NSIDKWSRMFFPITFSLFNVVYWLYYVH 133
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 41.1 bits (92), Expect = 0.006
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S+ Y ++ + R Y+I + +PS +V I +SF+L
Sbjct: 214 EWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPA 273
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYAT 218
+ N P ++ L N LP S I VY C ++ SLLE
Sbjct: 274 ESENRAPFKITL----LLGYNVFLLMMNDLLP-ASGTPLISVYFALCLSLMVVSLLETVF 328
Query: 219 VGYM 222
+ Y+
Sbjct: 329 ITYL 332
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 41.1 bits (92), Expect = 0.006
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S+ Y ++ + R Y+I + +PS +V I +SF+L
Sbjct: 214 EWELLGINKATPKMSMGNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPA 273
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLEYAT 218
+ N P ++ L N LP S I VY C ++ SLLE
Sbjct: 274 ESENRAPFKITL----LLGYNVFLLMMNDLLP-ASGTPLISVYFALCLSLMVVSLLETVF 328
Query: 219 VGYM 222
+ Y+
Sbjct: 329 ITYL 332
>Y18994-1|CAB60835.1| 99|Homo sapiens GABA-C receptor rho3 subunit
protein.
Length = 99
Score = 40.7 bits (91), Expect = 0.008
Identities = 14/25 (56%), Positives = 20/25 (80%)
Query: 333 IDKYSRIVFPVCFVCFNLMYWIIYL 357
ID YSRI+FP+ ++ FNL YW +Y+
Sbjct: 75 IDTYSRILFPIVYILFNLFYWGVYV 99
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLTE 322
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 179 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 238
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 239 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 297
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 298 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 328
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 35.9 bits (79), Expect = 0.23
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 35.9 bits (79), Expect = 0.23
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 35.9 bits (79), Expect = 0.23
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 214 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 273
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 274 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 325
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 35.9 bits (79), Expect = 0.23
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 199 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 258
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 259 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 310
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 35.9 bits (79), Expect = 0.23
Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 8/117 (6%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL-- 159
++++LG + ++S Y ++ + R Y+I + +PSG +V I +SF+L
Sbjct: 229 EWELLGLSKATAKLSRGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPV 288
Query: 160 -NRNATPARVALGXXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ N P ++ L + LP S I VY C ++ SLLE
Sbjct: 289 KSGNRVPFKITL----LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 340
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 35.9 bits (79), Expect = 0.23
Identities = 34/151 (22%), Positives = 64/151 (42%), Gaps = 5/151 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGXXXXXXXXXXXXXX 185
+ R +Y++ + +PS ++++ V F+L N + RV+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN-SGERVSFKITLLLGYSVFLIIV 291
Query: 186 NAALPKISY-VKSIDVYLGTCFVMVFASLLE 215
+ LP + I VY C ++ SL E
Sbjct: 292 SDTLPATAIGTPLIGVYFVVCMALLVISLAE 322
>AY341344-1|AAQ76830.1| 148|Homo sapiens GRINL1A downstream protein
Gdown4 protein.
Length = 148
Score = 33.5 bits (73), Expect = 1.2
Identities = 26/95 (27%), Positives = 38/95 (40%), Gaps = 6/95 (6%)
Query: 239 IASEKKLPECPPVGDPHTLSKMNTLSRCPPSR---PSKTISQEVRFKVHDPK---AHSKG 292
+A+ + PE PP DP ++ + CPP R P++ + R + + A G
Sbjct: 1 MATPARAPESPPSADPALVAGPAEEAECPPPRQPQPAQNVLAAPRLRAPSSRGLGAAEFG 60
Query: 293 GTLENTINGGRGGADEENPGPHPIHPGKDISKLLG 327
G N G A + GP PG S LG
Sbjct: 61 GAAGNVEAPGETFAQRVSWGPAESPPGSFSSSSLG 95
>AL137797-2|CAI19184.1| 377|Homo sapiens diencephalon/mesencephalon
homeobox 1 protein.
Length = 377
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 164 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 221
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
RG ++PG I P LLG + S
Sbjct: 222 RGSPKADSPGSLTITPVAPGGGLLGPSHS 250
>AL137797-1|CAI19185.1| 382|Homo sapiens diencephalon/mesencephalon
homeobox 1 protein.
Length = 382
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 169 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 226
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
RG ++PG I P LLG + S
Sbjct: 227 RGSPKADSPGSLTITPVAPGGGLLGPSHS 255
>AF398528-1|AAM90590.1| 382|Homo sapiens homeoprotein MBX-L
protein.
Length = 382
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 169 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 226
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
RG ++PG I P LLG + S
Sbjct: 227 RGSPKADSPGSLTITPVAPGGGLLGPSHS 255
>AF398527-1|AAM90589.1| 377|Homo sapiens homeoprotein MBX-S
protein.
Length = 377
Score = 33.5 bits (73), Expect = 1.2
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 164 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 221
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
RG ++PG I P LLG + S
Sbjct: 222 RGSPKADSPGSLTITPVAPGGGLLGPSHS 250
>AJ437318-1|CAD24817.1| 454|Homo sapiens 5-hydroxytryptamine
3-receptor subunit D protein.
Length = 454
Score = 33.1 bits (72), Expect = 1.6
Identities = 14/60 (23%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 102 QFKVLGHRQRAMEISLTTGNYSRLACEIQFVRSM--GYYLIQIYIPSGLIVIISWVSFWL 159
++ +LG ++R +++++ T Y + + R Y++ +PSG+++ I +SF+L
Sbjct: 194 EWVLLGIQKRTIKVTVATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYL 253
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 32.3 bits (70), Expect = 2.9
Identities = 30/104 (28%), Positives = 44/104 (42%), Gaps = 12/104 (11%)
Query: 115 ISLTTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWL---NRNATPARVALG 171
+S T SR+A R Y+I + +PSG +V I +SF+L + N P ++ L
Sbjct: 149 LSKATAKLSRVAIR----RRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITL- 203
Query: 172 XXXXXXXXXXXXXXNAALPKISYVKSIDVYLGTCFVMVFASLLE 215
+ LP S I VY C ++ SLLE
Sbjct: 204 ---LLGYNVFLLMMSDLLP-TSGTPLIGVYFALCLSLMVGSLLE 243
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 32.3 bits (70), Expect = 2.9
Identities = 23/98 (23%), Positives = 48/98 (48%), Gaps = 3/98 (3%)
Query: 69 ITLTTVGYTMRDIRYKWNEGPNSVGVSSEVSLPQ--FKVLGHRQRAMEISLTTGNY-SRL 125
+T T+ +T++DI P V V + Q +++LG E S+ + NY + +
Sbjct: 173 LTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEM 232
Query: 126 ACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNA 163
+ R +Y++ + +PS ++++ V F+L N+
Sbjct: 233 KFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS 270
>AB037699-1|BAC00920.1| 382|Homo sapiens PaxB protein.
Length = 382
Score = 32.3 bits (70), Expect = 2.9
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 3/89 (3%)
Query: 244 KLPECPPVGDPH-TLSKMNTLSRCPPSRPSKTISQEVRFKVHDPKAHSKGGTLENTINGG 302
+LP P + H +LS+ + P +P + ++ R DPKA G +
Sbjct: 169 RLPGSDPPAELHLSLSEQSASESAPEDQPDR--EEDPRAGAEDPKAEKSPGADSKGLGCK 226
Query: 303 RGGADEENPGPHPIHPGKDISKLLGMTPS 331
+G ++PG I P LLG + S
Sbjct: 227 KGSPKADSPGSLTITPVAPGGGLLGPSHS 255
>AL133561-1|CAB63715.1| 580|Homo sapiens hypothetical protein
protein.
Length = 580
Score = 30.7 bits (66), Expect = 8.7
Identities = 13/34 (38%), Positives = 17/34 (50%)
Query: 243 KKLPECPPVGDPHTLSKMNTLSRCPPSRPSKTIS 276
++LP P+G PH S M T R P+ T S
Sbjct: 106 RRLPRASPMGSPHRASPMRTPPRASPTGTPSTAS 139
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.420
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 56,026,649
Number of Sequences: 224733
Number of extensions: 2304677
Number of successful extensions: 4946
Number of sequences better than 10.0: 121
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 4576
Number of HSP's gapped (non-prelim): 336
length of query: 374
length of database: 73,234,838
effective HSP length: 91
effective length of query: 283
effective length of database: 52,784,135
effective search space: 14937910205
effective search space used: 14937910205
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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