Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000563-TA|BGIBMGA000563-PA|IPR005962|Tyrosine
3-monooxygenase, IPR001273|Aromatic amino acid hydroxylase
(561 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15; Endopte... 806 0.0
UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61; Coeloma... 473 e-132
UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;... 467 e-130
UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28; Deutero... 465 e-129
UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome s... 429 e-119
UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30; Euka... 423 e-117
UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135; Meta... 408 e-112
UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia japo... 407 e-112
UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3; Caenorha... 396 e-109
UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistos... 374 e-102
UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|R... 371 e-101
UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona in... 362 1e-98
UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep: CG91... 361 2e-98
UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona inte... 349 1e-94
UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n... 333 8e-90
UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3; Caenorhabd... 320 6e-86
UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, wh... 263 1e-68
UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid... 261 3e-68
UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=... 230 9e-59
UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3; Actinomy... 203 8e-51
UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1; Salini... 157 7e-37
UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan... 147 6e-34
UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4; Legio... 146 2e-33
UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1; Ricke... 142 3e-32
UniRef50_Q4THP6 Cluster: Chromosome undetermined SCAF2776, whole... 139 2e-31
UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1; Aci... 137 8e-31
UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66; Gamm... 137 8e-31
UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1; Morit... 134 4e-30
UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 130 1e-28
UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19; Vibr... 128 5e-28
UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 125 4e-27
UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1; Mesor... 124 6e-27
UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=... 121 4e-26
UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1; Hypho... 118 3e-25
UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2; Alpha... 118 4e-25
UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8; Prote... 118 4e-25
UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 117 1e-24
UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna... 116 2e-24
UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40; Prot... 116 2e-24
UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1; S... 113 2e-23
UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1; Ocean... 111 4e-23
UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4; Sphin... 111 5e-23
UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3; C... 110 8e-23
UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric ... 102 2e-20
UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1; Cytop... 90 1e-16
UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylas... 84 8e-15
UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase biopteri... 83 1e-14
UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyc... 82 3e-14
UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative; ... 73 3e-11
UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1; E... 67 1e-09
UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-08
UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1; Bac... 61 7e-08
UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1; Pedob... 61 9e-08
UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5; C... 59 3e-07
UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13; Ba... 56 2e-06
UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1; ... 55 4e-06
UniRef50_Q55658 Cluster: Sll0023 protein; n=1; Synechocystis sp.... 37 1.6
UniRef50_A2FAA9 Cluster: Putative uncharacterized protein; n=1; ... 36 2.2
UniRef50_A0DNH6 Cluster: Chromosome undetermined scaffold_58, wh... 36 2.2
UniRef50_A6SP41 Cluster: Predicted protein; n=1; Botryotinia fuc... 36 2.8
UniRef50_Q4QCC9 Cluster: Putative uncharacterized protein; n=3; ... 35 5.0
UniRef50_A6WN31 Cluster: Putative uncharacterized protein; n=1; ... 35 6.6
UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_0078... 34 8.7
UniRef50_Q8F1U5 Cluster: Molybdate metabolism regulator; n=2; Le... 34 8.7
UniRef50_A6GBQ3 Cluster: Putative uncharacterized protein; n=1; ... 34 8.7
UniRef50_A3IP91 Cluster: Putative uncharacterized protein; n=3; ... 34 8.7
UniRef50_O97291 Cluster: Putative uncharacterized protein MAL3P7... 34 8.7
>UniRef50_P18459 Cluster: Tyrosine 3-monooxygenase; n=15;
Endopterygota|Rep: Tyrosine 3-monooxygenase - Drosophila
melanogaster (Fruit fly)
Length = 579
Score = 806 bits (1994), Expect = 0.0
Identities = 393/575 (68%), Positives = 454/575 (78%), Gaps = 19/575 (3%)
Query: 1 MAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQSVLEEARARAND 60
MAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQ+VLEEAR++AND
Sbjct: 2 MAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQTVLEEARSKAND 61
Query: 61 SGLESDFIQDGVHI------------GNGDNSPT-----VEDGTQQD--ETKNXXXXXXX 101
LE +Q HI N +N P VE+ + + E +
Sbjct: 62 DSLEDCIVQAQEHIPSEQDVELQDEHANLENLPLEEYVPVEEDVEFESVEQEQSESQSQE 121
Query: 102 XXXXXXXXXXXYTLTEEEVILQNXXXXXXXXXXXXXXXXXXXHMRDGMGSLARILKTIDN 161
Y LTE+E++L N +++G+ SL RILK I+
Sbjct: 122 PEGNQQPTKNDYGLTEDEILLANAASESSDAEAAMQSAALVVRLKEGISSLGRILKAIET 181
Query: 162 YKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQSTAFAGVNLLTENNISSK 221
+ G VQH+E+R S+V GV D L+K+ MTR NL+QLIRSLRQS +F+ +NL+ +NN++ K
Sbjct: 182 FHGTVQHVESRQSRVEGVDHDVLIKLDMTRGNLLQLIRSLRQSGSFSSMNLMADNNLNVK 241
Query: 222 TPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSI 281
PWFP+HAS+LDNCNHLMTKYEP+LDMNHPGFADK YR+RRK+IAEIAFAYKYGDPIP I
Sbjct: 242 APWFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFI 301
Query: 282 AYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKH 341
Y+++E TW+ VF TV DL PKHAC EY+AAF+KLQ IFV R+PQL+++S FLRK+
Sbjct: 302 DYSDVEVKTWRSVFKTVQDLAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKN 361
Query: 342 TGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADP 401
TGF+LRPAAGLLTARDFLASLAFR+FQSTQYVRH NSP+HTPEPD IHELLGH+PLLADP
Sbjct: 362 TGFSLRPAAGLLTARDFLASLAFRIFQSTQYVRHVNSPYHTPEPDSIHELLGHMPLLADP 421
Query: 402 SFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHA 461
SFAQFSQEIGLASLGASD EIEKLSTVYWFTVEFGLCKE+ Q+KAYGA LLSS GELLHA
Sbjct: 422 SFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLCKEHGQIKAYGAGLLSSYGELLHA 481
Query: 462 LSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPH 521
+SDK E R FEPAST+VQPYQDQEYQPIYYVAE+FEDAKDKFRRWVSTMSRPFEVRFNPH
Sbjct: 482 ISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNPH 541
Query: 522 TERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 556
TERVEVLDSVDKLETL+ Q+NTE+LHLTNA+ KL+
Sbjct: 542 TERVEVLDSVDKLETLVHQMNTEILHLTNAISKLR 576
>UniRef50_P24529 Cluster: Tyrosine 3-monooxygenase; n=61;
Coelomata|Rep: Tyrosine 3-monooxygenase - Mus musculus
(Mouse)
Length = 498
Score = 473 bits (1167), Expect = e-132
Identities = 225/408 (55%), Positives = 297/408 (72%), Gaps = 9/408 (2%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQ---VTGVQFDALVKVSMTRINLIQLIRSLRQSTAF 207
SL+R LK + ++ + HLETRP+Q + V+ + +L L+ S+R+ +
Sbjct: 96 SLSRALKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSD- 154
Query: 208 AGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAE 267
V E+ K PWFPR S+LD C+HL+TK++P+LD++HPGF+D+ YR+RRK IAE
Sbjct: 155 -DVRSARED----KVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAE 209
Query: 268 IAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHR 327
IAF YK G+PIP + YT+ E TW+ V+ T+ L HACRE+ AF+ L+ +
Sbjct: 210 IAFQYKQGEPIPHVEYTKEEIATWKEVYATLKGLYATHACREHLEAFQLLERYCGYREDS 269
Query: 328 IPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDC 387
IPQLEDVS FL++ TGF LRP AGLL+ARDFLASLAFRVFQ TQY+RH +SP H+PEPDC
Sbjct: 270 IPQLEDVSHFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDC 329
Query: 388 IHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAY 447
HELLGH+P+LAD +FAQFSQ+IGLASLGASD EIEKLSTVYWFTVEFGLCK+N +LKAY
Sbjct: 330 CHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAY 389
Query: 448 GAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWV 507
GA LLSS GELLH+LS++PE+R F+P + +VQPYQDQ YQP+Y+V+E+F DAKDK R +
Sbjct: 390 GAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYA 449
Query: 508 STMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 555
S + RPF V+F+P+T ++VLDS + + + E+ LT A+ +
Sbjct: 450 SRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAI 497
>UniRef50_UPI000058423F Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 522
Score = 467 bits (1152), Expect = e-130
Identities = 214/408 (52%), Positives = 293/408 (71%), Gaps = 3/408 (0%)
Query: 148 GMGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQSTAF 207
G GSL+ L+ K + H+E+RPS Q + L++ + ++ +L++
Sbjct: 117 GFGSLSEALRVFQKRKVTLTHVESRPSNKIDGQIEFLMQCETKGSSSKNVLTALQK---V 173
Query: 208 AGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAE 267
A L + I+ + PWFP +LD C HL++ YEP+LD HPGF DKDYRERR++IA+
Sbjct: 174 ADNVRLEKEEITKRGPWFPTRVHELDRCTHLLSNYEPDLDDEHPGFTDKDYRERRQRIAD 233
Query: 268 IAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHR 327
+AF YK+G PIP + YT+ E TW ++ + L P HAC+E+ AF L+ ++
Sbjct: 234 VAFKYKHGQPIPRVEYTDDELRTWGLIYRQLKALFPTHACKEHIDAFNILEKEGLYSESF 293
Query: 328 IPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDC 387
IPQ EDVS+FL+ TGF LRP AGLL+ARDFLASLAFRVFQ+TQYVRH+++P HTPEPDC
Sbjct: 294 IPQHEDVSNFLKGKTGFQLRPVAGLLSARDFLASLAFRVFQATQYVRHSSAPMHTPEPDC 353
Query: 388 IHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAY 447
HELLGH+P+LADP+FAQFSQEIGLASLG +D +I +L+T+YWFTVEFGLC++N + +A
Sbjct: 354 CHELLGHVPMLADPTFAQFSQEIGLASLGVADEDITRLATLYWFTVEFGLCRQNGETRAC 413
Query: 448 GAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWV 507
GA LLS+ GEL +ALSDKPE RPFEP T++Q YQD+ YQPIY+VA++F DA+ K R +
Sbjct: 414 GAGLLSAFGELQYALSDKPEHRPFEPNKTAIQEYQDKNYQPIYFVADSFSDAQSKLRLYA 473
Query: 508 STMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 555
M+RP+ VR++P+T+ ++V+D VDKL I LN +M+ LT+A++KL
Sbjct: 474 MKMARPYNVRYDPYTQSIQVIDKVDKLRDAIRDLNGQMVVLTSAIEKL 521
>UniRef50_P07101 Cluster: Tyrosine 3-monooxygenase; n=28;
Deuterostomia|Rep: Tyrosine 3-monooxygenase - Homo
sapiens (Human)
Length = 528
Score = 465 bits (1146), Expect = e-129
Identities = 218/408 (53%), Positives = 293/408 (71%), Gaps = 9/408 (2%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQ---VTGVQFDALVKVSMTRINLIQLIRSLRQSTAF 207
+L+R +K + ++ + HLETRP+Q G + V++ + R +L L+ +RQ
Sbjct: 126 ALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQ---- 181
Query: 208 AGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAE 267
V+ + K PWFPR S+LD C+HL+TK++P+LD++HPGF+D+ YR+RRK IAE
Sbjct: 182 --VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAE 239
Query: 268 IAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHR 327
IAF Y++GDPIP + YT E TW+ V+ T+ L HAC E+ AF L+ +
Sbjct: 240 IAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDN 299
Query: 328 IPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDC 387
IPQLEDVS FL++ TGF LRP AGLL+ARDFLASLAFRVFQ TQY+RH +SP H+PEPDC
Sbjct: 300 IPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDC 359
Query: 388 IHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAY 447
HELLGH+P+LAD +FAQFSQ+IGLASLGASD EIEKLST+ WFTVEFGLCK+N ++KAY
Sbjct: 360 CHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLSWFTVEFGLCKQNGEVKAY 419
Query: 448 GAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWV 507
GA LLSS GELLH LS++PE+R F+P + +VQPYQDQ YQ +Y+V+E+F DAKDK R +
Sbjct: 420 GAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYA 479
Query: 508 STMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 555
S + RPF V+F+P+T ++VLDS + + + E+ L +A+ +
Sbjct: 480 SRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAI 527
>UniRef50_Q4SDY9 Cluster: Chromosome 13 SCAF14627, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF14627, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 488
Score = 429 bits (1058), Expect = e-119
Identities = 214/435 (49%), Positives = 298/435 (68%), Gaps = 36/435 (8%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQVTGVQFDAL---VKVSMTRINLIQLIRSLRQSTAF 207
+L+R LK + ++ + HLETRP + + L V+ + ++ LI SL+++
Sbjct: 60 ALSRTLKVFETFEAKIHHLETRPCRKLKDNQEGLEYFVRCEVHLSDVSTLIGSLKRNAE- 118
Query: 208 AGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAE 267
++ T + K WFP+ +DLD C+HL+TK++P+LD +HPG+ D YR+RRK I +
Sbjct: 119 ---DVKTTKEV--KFHWFPKKIADLDKCHHLVTKFDPDLDQDHPGYTDAAYRQRRKMIGD 173
Query: 268 IAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHR 327
+AF Y++G+ IP + YTE E GTW+ V+ T+ DL HAC E+ AF L+ + P
Sbjct: 174 VAFRYRHGESIPRVEYTEEEIGTWREVYLTLRDLYATHACSEHLEAFRLLEKHCGYSPDN 233
Query: 328 IPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDC 387
IPQLEDVS FL++ TGFTLRP AGLL+ARDFLASLAFRVFQ TQY+RH +SP H+PEPDC
Sbjct: 234 IPQLEDVSCFLKERTGFTLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDC 293
Query: 388 IHELLGHIPLLADPSFAQFSQEIG----------------------LASL-----GASDS 420
+HELLGH+P+LA+ +FAQFSQ G L SL GASD
Sbjct: 294 VHELLGHVPMLANSTFAQFSQVRGRQRTFCPLRLSYVFANSPWIHPLQSLGLASLGASDE 353
Query: 421 EIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQP 480
+IEKLST+YWFTVE+GLCK+N ++KAYGA LLSS GEL+H+LSD+PE+R F+P + +VQP
Sbjct: 354 DIEKLSTLYWFTVEYGLCKQNGEVKAYGAGLLSSYGELVHSLSDEPEVREFDPDAAAVQP 413
Query: 481 YQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQ 540
YQDQ YQP+Y+++E+F DAK+KFRR+V+ + RPF VRF+P+T +EVLD+ K++ +
Sbjct: 414 YQDQTYQPVYFISESFADAKEKFRRYVAGIKRPFSVRFDPYTTSIEVLDNPLKIQGGLEG 473
Query: 541 LNTEMLHLTNAVKKL 555
+ E+ L +A+ L
Sbjct: 474 VKDELKMLADALSVL 488
>UniRef50_P00439 Cluster: Phenylalanine-4-hydroxylase; n=30;
Eukaryota|Rep: Phenylalanine-4-hydroxylase - Homo
sapiens (Human)
Length = 452
Score = 423 bits (1041), Expect = e-117
Identities = 203/413 (49%), Positives = 277/413 (67%), Gaps = 2/413 (0%)
Query: 145 MRDGMGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRIN-LIQLIRSLRQ 203
+++ +G+LA++L+ + + H+E+RPS++ +++ + + L +I+ LR
Sbjct: 41 LKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRH 100
Query: 204 STAFAGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRK 263
A V+ L+ + PWFPR +LD + + Y ELD +HPGF D YR RRK
Sbjct: 101 DIG-ATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRK 159
Query: 264 QIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIF 323
Q A+IA+ Y++G PIP + Y E E TW VF T+ L HAC EY F L+ F
Sbjct: 160 QFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGF 219
Query: 324 VPHRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTP 383
IPQLEDVS FL+ TGF LRP AGLL++RDFL LAFRVF TQY+RH + P +TP
Sbjct: 220 HEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTP 279
Query: 384 EPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQ 443
EPD HELLGH+PL +D SFAQFSQEIGLASLGA D IEKL+T+YWFTVEFGLCK+
Sbjct: 280 EPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDS 339
Query: 444 LKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKF 503
+KAYGA LLSS GEL + LS+KP+L P E T++Q Y E+QP+YYVAE+F DAK+K
Sbjct: 340 IKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKV 399
Query: 504 RRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 556
R + +T+ RPF VR++P+T+R+EVLD+ +L+ L +N+E+ L +A++K+K
Sbjct: 400 RNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK 452
>UniRef50_Q8IWU9 Cluster: Tryptophan 5-hydroxylase 2; n=135;
Metazoa|Rep: Tryptophan 5-hydroxylase 2 - Homo sapiens
(Human)
Length = 490
Score = 408 bits (1005), Expect = e-112
Identities = 192/415 (46%), Positives = 269/415 (64%), Gaps = 4/415 (0%)
Query: 145 MRDGMGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQS 204
+++ +G L + L+ + + H+E+R S+ + + V + +LI+ L+
Sbjct: 70 LKNEVGGLVKALRLFQEKRVNMVHIESRKSRRRSSEVEIFVDCECGKTEFNELIQLLKFQ 129
Query: 205 TAFAGVN----LLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRE 260
T +N + TE PWFPR S+LD C+H + Y ELD +HPGF D YR+
Sbjct: 130 TTIVTLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQ 189
Query: 261 RRKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAA 320
RRK ++A YKYG PIP + YTE E TW VF + L P HACREY F L
Sbjct: 190 RRKYFVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKY 249
Query: 321 DIFVPHRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPF 380
+ +PQLEDVS FL++ +GFT+RP AG L+ RDFLA LA+RVF TQY+RH + P
Sbjct: 250 CGYREDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPL 309
Query: 381 HTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKE 440
+TPEPD HELLGH+PLLADP FAQFSQEIGLASLGASD +++KL+T Y+FT+EFGLCK+
Sbjct: 310 YTPEPDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQ 369
Query: 441 NQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAK 500
QL+AYGA LLSSIGEL HALSDK ++ F+P +T +Q +Q Y+V+E+FE+AK
Sbjct: 370 EGQLRAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAK 429
Query: 501 DKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 555
+K R + +++RPF V FNP+T+ +E+L +E ++ L +++ + +A+ K+
Sbjct: 430 EKMRDFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALNKM 484
>UniRef50_A6P4D3 Cluster: Tyrosine hydroxylase; n=1; Dugesia
japonica|Rep: Tyrosine hydroxylase - Dugesia japonica
(Planarian)
Length = 488
Score = 407 bits (1001), Expect = e-112
Identities = 176/307 (57%), Positives = 238/307 (77%)
Query: 224 WFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSIAY 283
W P+H SDLD+CNHLM K++PE+ +HPGF DK Y+ RR +IAEIAF +KYGD IP + Y
Sbjct: 154 WIPKHISDLDSCNHLMLKFQPEMASDHPGFHDKIYKSRRMEIAEIAFNFKYGDKIPRVEY 213
Query: 284 TEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHTG 343
E E TW+ + T+ L +AC+E +KL+ + P+ IPQLED+S++L+K +G
Sbjct: 214 FESEKETWREAYITLTSLYKDYACKEQLIGIKKLEEKCGYGPNDIPQLEDISNYLKKTSG 273
Query: 344 FTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPSF 403
F LRP AGLL+ARDFLASLAFRVFQ TQY RH++ P HTPEPDCIHELLGH+P+L+D F
Sbjct: 274 FQLRPVAGLLSARDFLASLAFRVFQCTQYTRHHSKPLHTPEPDCIHELLGHVPMLSDAEF 333
Query: 404 AQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALS 463
A+FSQEIGL SLGASDS+IE+L+T+YWFT+EFGLC EN+++KA+GA LLSS GEL HA+S
Sbjct: 334 AEFSQEIGLCSLGASDSDIERLATLYWFTIEFGLCYENKKIKAFGAGLLSSFGELKHAIS 393
Query: 464 DKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTE 523
+ PE R F+P SV PY+D++YQP+YYV ++ D K+K R++ ++ R +R++P+TE
Sbjct: 394 NIPEHRNFDPQVASVTPYKDEDYQPVYYVIDSVTDMKEKVRQFAKSIKRQNPIRYDPYTE 453
Query: 524 RVEVLDS 530
+E+L++
Sbjct: 454 TIEILNN 460
>UniRef50_P90986 Cluster: Tyrosine 3-monooxygenase; n=3;
Caenorhabditis|Rep: Tyrosine 3-monooxygenase -
Caenorhabditis elegans
Length = 454
Score = 396 bits (975), Expect = e-109
Identities = 193/406 (47%), Positives = 265/406 (65%), Gaps = 7/406 (1%)
Query: 155 ILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQS-TAFAGVNLL 213
IL+ + + K + H+ETR ++ + D L+ T+ LI L Q+ A ++
Sbjct: 47 ILQNMSSAKVQICHVETRGNEAS---HDVLLACKATKNQLIHSAELLTQNHVALTKFSIF 103
Query: 214 TENNISSKTP---WFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAF 270
+ K WFPRH S+LD C+ +TKYEP D HPG D Y RRK + + A
Sbjct: 104 AKKLSDEKNQSQIWFPRHISELDQCSKCITKYEPTTDPRHPGHGDVAYIARRKFLNDQAL 163
Query: 271 AYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQ 330
+K+GD I + YTE E+ TW+ V+ + DL H C Y+ + LQ + RIPQ
Sbjct: 164 EFKFGDEIGYVDYTEEEHATWKAVYEKLGDLHLSHTCAVYRQNLKILQEEKVLTADRIPQ 223
Query: 331 LEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHE 390
+ DV+ FL+K TGF LRP +GLL+ARDFLASLAFRVFQ+T Y+RH+ SP H+PEPD IHE
Sbjct: 224 IRDVNKFLQKKTGFELRPCSGLLSARDFLASLAFRVFQTTTYLRHHKSPHHSPEPDLIHE 283
Query: 391 LLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAA 450
LLGH+P+ +DP AQ SQ+IGL SLGASD IEKLSTVYWF VEFGLCKE+ +LKA GA
Sbjct: 284 LLGHVPMFSDPLLAQMSQDIGLMSLGASDEHIEKLSTVYWFIVEFGLCKEDGKLKAIGAG 343
Query: 451 LLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTM 510
LLS+ GEL+HA SD PE + F+PA T+VQ Y+D +YQP+Y+VA++ DA K R++ S+M
Sbjct: 344 LLSAYGELMHACSDAPEHKDFDPAVTAVQKYEDDDYQPLYFVADSIHDALAKLRKYASSM 403
Query: 511 SRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKLK 556
RPF V ++P T+ +E ++S LE +L+ ++ +T+A ++K
Sbjct: 404 DRPFSVVYDPFTKSIEAIESSADLEKAFSRLSNDLSAITHAADRMK 449
>UniRef50_O17446 Cluster: Tyrosine 3-monooxygenase; n=1; Schistosoma
mansoni|Rep: Tyrosine 3-monooxygenase - Schistosoma
mansoni (Blood fluke)
Length = 465
Score = 374 bits (921), Expect = e-102
Identities = 184/382 (48%), Positives = 248/382 (64%), Gaps = 8/382 (2%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQVTG-----VQFDALVKVSMTRINLIQLIRSLRQST 205
+L ILK I + K + H ETRP+ VQ+ L+ + IN+ L LR ++
Sbjct: 54 TLHEILKYIIDKKLNLVHFETRPTLTLSNANRDVQYSCLITLEANEINMSLLYEELRGNS 113
Query: 206 AFAGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQI 265
+G+NLL NN S+ W+P+H SDLD C HL+ K++PEL +HPGF DK YRERR+ I
Sbjct: 114 FISGINLL--NNQESED-WYPKHISDLDKCQHLLRKFQPELQTDHPGFHDKVYRERREAI 170
Query: 266 AEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVP 325
A+IAF YKYGD IP + YT+ E TW VF + + ACREY F+ L+ +
Sbjct: 171 AKIAFQYKYGDRIPEVEYTKEEIETWGLVFTKMKAVHASRACREYIDGFQLLEKYCNYNS 230
Query: 326 HRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEP 385
IPQL+ + F+ + +GF +RP AGL++ +DFLASLAFRVFQ TQY+RH++ P HTPEP
Sbjct: 231 ESIPQLQTICEFMHRTSGFRIRPVAGLVSPKDFLASLAFRVFQCTQYIRHHSRPMHTPEP 290
Query: 386 DCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLK 445
DCIHEL+GH+P+L + FA FSQE+GLASLGAS+ EI +LST+YWFTVEFGLC EN + +
Sbjct: 291 DCIHELIGHMPMLVNRQFADFSQELGLASLGASEEEITRLSTLYWFTVEFGLCNENGETR 350
Query: 446 AYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRR 505
A GA ++SS GEL +A SD PF +VQ Y D YQ IY+V E+ E K + R
Sbjct: 351 ALGAGIMSSYGELENAFSDLSVKEPFNINDAAVQVYDDVGYQKIYFVTESIESMKRELRN 410
Query: 506 WVSTMSRPFEVRFNPHTERVEV 527
+++T + ++P TE V +
Sbjct: 411 YINTSGKSTIPIYDPITETVHM 432
>UniRef50_Q5DGG4 Cluster: SJCHGC01235 protein; n=2; Schistosoma|Rep:
SJCHGC01235 protein - Schistosoma japonicum (Blood
fluke)
Length = 497
Score = 371 bits (912), Expect = e-101
Identities = 173/333 (51%), Positives = 225/333 (67%)
Query: 223 PWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSIA 282
PWFPRH SDLD +H + Y ELD +HPGF D++YR RR A+IAF YK+G IP I
Sbjct: 141 PWFPRHISDLDEVSHHVLMYGKELDADHPGFKDEEYRRRRMMFADIAFTYKWGQQIPFID 200
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YTE E TW V+ + L ACRE++ LQ + +PQL+ VS FL+ T
Sbjct: 201 YTETEKMTWGCVYRELTRLYKTTACREFQKNLALLQDEAGYNEFDLPQLQVVSDFLKART 260
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
GF LRP AG L+ARDFL+ LAFRVF TQY+RH PF+TPEPDC HELLGH+P+LADP
Sbjct: 261 GFCLRPVAGYLSARDFLSGLAFRVFYCTQYIRHQGDPFYTPEPDCCHELLGHVPMLADPK 320
Query: 403 FAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHAL 462
FA+FSQEIGLASLG SD EI+KLST Y+FT+EFGLC++ QL+AYGA LLSS+ EL +AL
Sbjct: 321 FARFSQEIGLASLGTSDDEIKKLSTCYFFTIEFGLCRQENQLRAYGAGLLSSVAELQYAL 380
Query: 463 SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHT 522
SDK ++PF P + +Q Y+ +FEDA K R +V T+ RPF+VR+NP+T
Sbjct: 381 SDKAVIKPFIPMEVINEECLVTTFQNGYFETSSFEDATHKMREFVRTIRRPFDVRYNPYT 440
Query: 523 ERVEVLDSVDKLETLIWQLNTEMLHLTNAVKKL 555
+ +E+++S + LI L E+ + ++ K+
Sbjct: 441 QSIEIIESPGSVANLIQDLQFELTTINESLLKM 473
>UniRef50_Q5ZNC6 Cluster: Tyrosine 3-monooxygenase; n=1; Ciona
intestinalis|Rep: Tyrosine 3-monooxygenase - Ciona
intestinalis (Transparent sea squirt)
Length = 429
Score = 362 bits (891), Expect = 1e-98
Identities = 175/384 (45%), Positives = 245/384 (63%), Gaps = 2/384 (0%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQ-VTGVQFDALVKVSMTRINLIQLIRSLRQSTAFAG 209
++++I + + N V ++ETR + V ++ K +T I I + + G
Sbjct: 45 TMSQICEKLKNEDVIVSYIETRNGTLIKNVAGNSKYKFLITCIGNDNDITTGLKRLESIG 104
Query: 210 VNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIA 269
N WFPRH ++L+ C T YEP+ D NHPGF D Y ERR I+ A
Sbjct: 105 CKATIVNGTERTAEWFPRHVTELELCRGTKTDYEPDKDSNHPGFNDPVYVERRNYISNTA 164
Query: 270 FAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIP 329
YK+G IP++ YT + TW V+ T+ L HAC+ YK F++L+ + P++IP
Sbjct: 165 HFYKHGTDIPTVDYTNEDRQTWSVVYKTLKRLHATHACKVYKDNFQRLEKECGYSPNKIP 224
Query: 330 QLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIH 389
QL+ VS FL++ TGF L+PA G++T RDFLASLAF+VFQ TQY+RH SP H+PEPDC H
Sbjct: 225 QLQTVSEFLKEQTGFKLQPAPGIITPRDFLASLAFKVFQCTQYIRHPASPMHSPEPDCCH 284
Query: 390 ELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGA 449
EL+GHIP+L DP+FA +SQ+IGLASLG SDS+I KL+ +YWFTVEFGLCKEN LKAYGA
Sbjct: 285 ELIGHIPMLLDPTFALYSQQIGLASLGVSDSDITKLAALYWFTVEFGLCKENNVLKAYGA 344
Query: 450 ALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVS- 508
L+SS GEL HALSD P P + T +QPY+D YQPIY+V+E+F++A ++ R +
Sbjct: 345 GLMSSYGELQHALSDVPMHLPLQAERTCLQPYEDSVYQPIYFVSESFDEAFNQVRAFSQH 404
Query: 509 TMSRPFEVRFNPHTERVEVLDSVD 532
R F++ +N + ++ + ++
Sbjct: 405 CTKRGFDITYNENDGYIQTVPYIN 428
>UniRef50_Q9W0K2 Cluster: CG9122-PA; n=4; Endopterygota|Rep:
CG9122-PA - Drosophila melanogaster (Fruit fly)
Length = 555
Score = 361 bits (889), Expect = 2e-98
Identities = 189/428 (44%), Positives = 273/428 (63%), Gaps = 15/428 (3%)
Query: 145 MRDGMGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQS 204
+R+ +G+LAR L+ V HLE P ++ Q D LV V + L Q+++ L +
Sbjct: 85 LRNQVGNLARALQVFQELGINVLHLELSPLEMATNQADVLVDVECDQRRLDQVVKMLNRE 144
Query: 205 TA---FAGVN---LLTENNISSKTP-------WFPRHASDLDNCNHLMTKYEPELDMNHP 251
A + VN L ++S+ + WFPR SDLD +++ Y ELD +HP
Sbjct: 145 VASVNYTSVNTQGLARAPSLSACSSFDFGDMVWFPRKISDLDKAQNVLM-YGSELDADHP 203
Query: 252 GFADKDYRERRKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYK 311
GF D YR+RR+Q + IA +K+G+PIP + YT E TW VF + L HA EY
Sbjct: 204 GFKDPVYRKRREQFSAIANNFKHGNPIPRVQYTPEEVKTWGTVFLELHRLYVLHAVPEYM 263
Query: 312 AAFEKLQAADIFVPHRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQ 371
+ +L+ + +PQL+DVS +L++ TGF LRP AG L+ RDFL+ LAFRVF TQ
Sbjct: 264 DNWPELEKYCGYREDNVPQLQDVSVYLKRKTGFQLRPVAGYLSPRDFLSGLAFRVFHCTQ 323
Query: 372 YVRHNNSPFHTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWF 431
Y+RH++ PF+TPEPDC HELLGH+PLLA+ SFAQFSQEIGLASLGASD++IEKL+T+Y+F
Sbjct: 324 YIRHSSDPFYTPEPDCCHELLGHMPLLANSSFAQFSQEIGLASLGASDADIEKLATLYFF 383
Query: 432 TVEFGLCKE-NQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIY 490
TVEFGLCK+ + K YGA LLSS+ EL HA++ + +++ F+P T Q YQ Y
Sbjct: 384 TVEFGLCKQADSTFKVYGAGLLSSVAELQHAITAENKIKKFDPEVTCQQECIITSYQNAY 443
Query: 491 YVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTN 550
Y ++FE+AK++ R + ++ RPF VR+NP+T VEVL + K+ ++ +L ++ + +
Sbjct: 444 YYTDSFEEAKEQMRAFAESIQRPFGVRYNPYTMSVEVLSNAKKITAVVSELRGDLSIVCS 503
Query: 551 AVKKLKGS 558
A++K+ +
Sbjct: 504 ALRKISAT 511
>UniRef50_A1Y9J6 Cluster: Tryptophan hydroxylase; n=1; Ciona
intestinalis|Rep: Tryptophan hydroxylase - Ciona
intestinalis (Transparent sea squirt)
Length = 448
Score = 349 bits (858), Expect = 1e-94
Identities = 160/370 (43%), Positives = 238/370 (64%)
Query: 192 INLIQLIRSLRQSTAFAGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHP 251
+ L +L L + F G++ +T+ N WFP+ +DLD C + Y ELD +HP
Sbjct: 77 VELEKLETILTKLKLFPGISQITKENTKENGIWFPKCLADLDGCAKNVLMYGAELDADHP 136
Query: 252 GFADKDYRERRKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYK 311
GF D+ YR+RR ++A +++GD IP + YT+IE TW +V+ +++L P AC ++
Sbjct: 137 GFKDEVYRKRRDYFTKLAMDFRHGDKIPRVEYTKIEIETWGKVYKELMELHPTRACAQHL 196
Query: 312 AAFEKLQAADIFVPHRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQ 371
L +PQLED+S+FL+ TGF +RPAAG L+ RDFLA LAFRVF TQ
Sbjct: 197 KNLPLLSEFCKCSEDNVPQLEDISAFLQSRTGFRIRPAAGFLSPRDFLAGLAFRVFNCTQ 256
Query: 372 YVRHNNSPFHTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWF 431
Y+RH++ P++TPEPD HE+LGH+PLLADP FAQFSQEIGLASLG SD + KL+ Y +
Sbjct: 257 YIRHHSDPYYTPEPDICHEILGHVPLLADPEFAQFSQEIGLASLGVSDQDTSKLAGCYLY 316
Query: 432 TVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYY 491
TVEFGLCKE +KAYGA LLSSI EL HALS ++R F+ + S Q +QP+Y+
Sbjct: 317 TVEFGLCKEQDGIKAYGAGLLSSISELKHALSSPEKVRAFDAVTASCQESHVTAFQPVYF 376
Query: 492 VAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNA 551
++ +F AK + R + +T+ RPF + F+ T V+V D + +++ + +++ +++ ++ A
Sbjct: 377 LSPSFSQAKHEMRAFAATLERPFVLSFDEETSSVKVFDKLSSIQSAVSKMSHDLVVISKA 436
Query: 552 VKKLKGSHFE 561
+ +++ E
Sbjct: 437 LGEMEKRKIE 446
>UniRef50_Q6WRI4 Cluster: Aromatic amino acid hydroxylase-like; n=3;
Leishmania|Rep: Aromatic amino acid hydroxylase-like -
Leishmania major
Length = 453
Score = 333 bits (818), Expect = 8e-90
Identities = 154/308 (50%), Positives = 205/308 (66%), Gaps = 4/308 (1%)
Query: 223 PWFPRHASDLDNCNHLMTKYEPELDMN----HPGFADKDYRERRKQIAEIAFAYKYGDPI 278
PW+P DLD + EL + HPGF D+ YR RR++I +A YK GDPI
Sbjct: 125 PWYPTEPKDLDELDQSTLAAGEELQEDPENPHPGFHDEVYRARRREIVGLAKNYKTGDPI 184
Query: 279 PSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFL 338
P + YTE EN W V++ + L P HAC++Y F L + + PQL DVS FL
Sbjct: 185 PIVNYTEEENRVWTVVYDHLTRLYPTHACQQYNYVFPLLLENGVLSRTKTPQLRDVSEFL 244
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
+ TGFT+RP GLLT+RDFL +LAFRVF STQY+RH P +TPEPD +H+++GH+PLL
Sbjct: 245 NEATGFTVRPVTGLLTSRDFLNALAFRVFYSTQYIRHAAQPLYTPEPDMVHDIIGHLPLL 304
Query: 399 ADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGEL 458
+DP FA F+Q IGLASLGASD ++KL+ VYW++VEFGLC E + KAYGA +LSS GEL
Sbjct: 305 SDPDFANFTQTIGLASLGASDELLDKLAKVYWYSVEFGLCSEGGRRKAYGAGILSSCGEL 364
Query: 459 LHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRF 518
+ALSDKPE P++P S P+ +YQP+Y+VAE+F DA+ K W+S+ +P +
Sbjct: 365 EYALSDKPECVPWDPTMASKTPFPITKYQPLYFVAESFSDAQRKLEAWLSSQEKPLYTVY 424
Query: 519 NPHTERVE 526
N ++ RV+
Sbjct: 425 NSYSRRVQ 432
>UniRef50_Q9XZD1 Cluster: Tryptophan hydroxylase; n=3;
Caenorhabditis|Rep: Tryptophan hydroxylase -
Caenorhabditis elegans
Length = 532
Score = 320 bits (786), Expect = 6e-86
Identities = 158/350 (45%), Positives = 221/350 (63%), Gaps = 13/350 (3%)
Query: 216 NNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAFAYKYG 275
++ ++ + WFP+ DLD C + Y LD +HPGF D +YR+RR AE+A YK+G
Sbjct: 179 DDATTGSEWFPKSIYDLDICAKRVIMYGAGLDADHPGFKDTEYRQRRMMFAELALNYKHG 238
Query: 276 DPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVS 335
+PIP YT E TW ++ + +L KHAC+++ FE L+ + + IPQLED+
Sbjct: 239 EPIPRTEYTSSERKTWGIIYRKLRELHKKHACKQFLDNFELLERHCGYSENNIPQLEDIC 298
Query: 336 SFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHI 395
FL+ TGF +RP AG L+ARDFLA LA+RVF TQYVRH+ PF+TPEPD +HEL+GH+
Sbjct: 299 KFLKAKTGFRVRPVAGYLSARDFLAGLAYRVFFCTQYVRHHADPFYTPEPDTVHELMGHM 358
Query: 396 PLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGL---------CKEN----Q 442
L ADP FAQFSQEIGLASLGAS+ +++KL+T+Y+F++EFGL KEN +
Sbjct: 359 ALFADPDFAQFSQEIGLASLGASEEDLKKLATLYFFSIEFGLSSDDAADSPVKENGSNHE 418
Query: 443 QLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDK 502
+ K YGA LLSS GEL HA+ + F+P Q +Q Y+ FE+A+ K
Sbjct: 419 RFKVYGAGLLSSAGELQHAVEGSATIIRFDPDRVVEQECLITTFQSAYFYTRNFEEAQQK 478
Query: 503 FRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNAV 552
R + + M RPF VR+NP+TE VEVL++ + + L +++ L A+
Sbjct: 479 LRMFTNNMKRPFIVRYNPYTESVEVLNNSRSIMLAVNSLRSDINLLAGAL 528
>UniRef50_A0C973 Cluster: Chromosome undetermined scaffold_16, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_16,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 431
Score = 263 bits (644), Expect = 1e-68
Identities = 136/381 (35%), Positives = 219/381 (57%), Gaps = 9/381 (2%)
Query: 146 RDGMGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQST 205
RD GSL ILK+ N+K + +ET T + +VK++ +I+ + L
Sbjct: 34 RDYYGSLRNILKSFSNHKINLSDIETLKLNRTAKGQNIVVKLTFEKIDDYKFNELLFDLQ 93
Query: 206 AFAGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQI 265
L+ ++ PW+PR+ DL +M E E + +HP F D +YR+RR++I
Sbjct: 94 QRYDEVLIDNDSQIPLVPWYPRNDEDLKTIGLIMEVKE-ENNQDHPQFKDHEYRKRREEI 152
Query: 266 AEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVP 325
A+++ + G+P+P I YTE E TW+++++ + + + K + Y K++ A F
Sbjct: 153 AKLSQQHLIGEPVPYINYTEQEEVTWKKIYSILRERVEKVMSQRYLRNLVKIENALGF-K 211
Query: 326 HRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEP 385
++IPQL D+ ++L+ TGF ++ G+L+ R+FL +L RVF TQY+RH+++P +TPEP
Sbjct: 212 YKIPQLRDIDAYLKAETGFRIKATHGILSQREFLNALGHRVFCCTQYIRHHSTPEYTPEP 271
Query: 386 DCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLK 445
D +HEL+GH+PL AD A SQEIG+ S G ++ +L T+YWFT+EFG CKEN Q+K
Sbjct: 272 DIVHELVGHVPLFADKEVADLSQEIGILSCGTEQKDLSRLGTLYWFTLEFGACKENGQIK 331
Query: 446 AYGAALLSSIGE-------LLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
+GA + SSIGE L K F+P + +PY Q QP+Y E+FE+
Sbjct: 332 GFGAGIASSIGECDVSNIQYLFQNFPKANYEKFDPFIHADRPYPIQTVQPVYMYTESFEE 391
Query: 499 AKDKFRRWVSTMSRPFEVRFN 519
A + + ++ +PF + ++
Sbjct: 392 AMQELIIFGKSLQKPFGLYYD 412
>UniRef50_Q23A76 Cluster: Biopterin-dependent aromatic amino acid
hydroxylase family protein; n=2; Tetrahymena thermophila
SB210|Rep: Biopterin-dependent aromatic amino acid
hydroxylase family protein - Tetrahymena thermophila
SB210
Length = 448
Score = 261 bits (640), Expect = 3e-68
Identities = 134/385 (34%), Positives = 218/385 (56%), Gaps = 10/385 (2%)
Query: 146 RDGMGSLARILKTIDNYKGCVQHLETR----PSQVTGVQFDALVKVSMTRINLIQLIRSL 201
RD +GSL+ +L + + +E++ V F + + N+ Q + L
Sbjct: 58 RDQVGSLSNVLDVFKQHSINLTQIESKLLNKRRDNQNVMFVCTFEGNRKYQNVQQAFQEL 117
Query: 202 RQSTAFAGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRER 261
+ F V E N+ PWFPR +DL + + E + + F D +YR+R
Sbjct: 118 QSK--FDIVKFSDETNV---VPWFPRDRNDLQYIGQDLMRVEEDNCKDSLQFTDTEYRKR 172
Query: 262 RKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAAD 321
R IA+++ ++ G PIP + YTE EN TW+ ++N L K C + ++ +
Sbjct: 173 RDYIAQVSKSHILGQPIPILEYTEQENQTWRTIYNK-LSSYHKDLCTDRYNYNKRQLERE 231
Query: 322 IFVPHRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFH 381
+ + ++IPQL D+ ++LR+ T F ++ A G+L+ R+FL +LA RVF STQY+RH+ + +
Sbjct: 232 LGIQNQIPQLRDLDAYLRQKTNFKIKAAHGILSQREFLNALAHRVFFSTQYIRHHKTVEY 291
Query: 382 TPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKEN 441
TPEPD +HE++GHIP+ ADP A SQEIGL S+GA+D ++ +L +YWFT+EFG CKEN
Sbjct: 292 TPEPDIVHEVVGHIPMFADPVVADISQEIGLLSIGANDEQLRRLGNIYWFTLEFGACKEN 351
Query: 442 QQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKD 501
++KAYGA ++ IGE H LS + +P + Y Q+ QP+Y +FE+ +
Sbjct: 352 GKMKAYGAGIIGCIGECEHFLSQNSRFKYLDPFKDCDREYPIQKVQPVYCYTNSFEECLE 411
Query: 502 KFRRWVSTMSRPFEVRFNPHTERVE 526
+ ++ M +P + ++ +TE +E
Sbjct: 412 RLVKFGEQMKKPMKTWYDFNTETIE 436
>UniRef50_Q0PWM2 Cluster: Tyrosine hydroxylase isoform D2,8,9; n=31;
Eutheria|Rep: Tyrosine hydroxylase isoform D2,8,9 - Homo
sapiens (Human)
Length = 407
Score = 230 bits (562), Expect = 9e-59
Identities = 107/200 (53%), Positives = 143/200 (71%)
Query: 356 RDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASL 415
R +A +AF+ R + DC HELLGH+P+LAD +FAQFSQ+IGLASL
Sbjct: 207 RKLIAEIAFQYRHGDPIPRVEYTAEEIATWDCCHELLGHVPMLADRTFAQFSQDIGLASL 266
Query: 416 GASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPAS 475
GASD EIEKLST+YWFTVEFGLCK+N ++KAYGA LLSS GELLH LS++PE+R F+P +
Sbjct: 267 GASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEA 326
Query: 476 TSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLE 535
+VQPYQDQ YQ +Y+V+E+F DAKDK R + S + RPF V+F+P+T ++VLDS +
Sbjct: 327 AAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVR 386
Query: 536 TLIWQLNTEMLHLTNAVKKL 555
+ + E+ L +A+ +
Sbjct: 387 RSLEGVQDELDTLAHALSAI 406
Score = 132 bits (319), Expect = 2e-29
Identities = 62/144 (43%), Positives = 93/144 (64%), Gaps = 9/144 (6%)
Query: 151 SLARILKTIDNYKGCVQHLETRPSQ---VTGVQFDALVKVSMTRINLIQLIRSLRQSTAF 207
+L+R +K + ++ + HLETRP+Q G + V++ + R +L L+ +RQ
Sbjct: 99 ALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQ---- 154
Query: 208 AGVNLLTENNISSKTPWFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAE 267
V+ + K PWFPR S+LD C+HL+TK++P+LD++HPGF+D+ YR+RRK IAE
Sbjct: 155 --VSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAE 212
Query: 268 IAFAYKYGDPIPSIAYTEIENGTW 291
IAF Y++GDPIP + YT E TW
Sbjct: 213 IAFQYRHGDPIPRVEYTAEEIATW 236
>UniRef50_Q3W6S6 Cluster: Tyrosine 3-monooxygenase; n=3;
Actinomycetales|Rep: Tyrosine 3-monooxygenase - Frankia
sp. EAN1pec
Length = 296
Score = 203 bits (496), Expect = 8e-51
Identities = 110/261 (42%), Positives = 155/261 (59%), Gaps = 9/261 (3%)
Query: 243 EPELDMNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLM 302
E L +HPG AD++Y+ RR QIAE+A ++ G P+P +AYTE E+ W+ V +
Sbjct: 20 EVRLARSHPGAADREYQARRNQIAELALRWRPGQPVPRVAYTEAEHAVWRLVTGKLALAY 79
Query: 303 PKHACREYKAAFEKLQAADIFVP-HRIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLAS 361
AC E+ AA + +P RIPQL++VS L + TGF PAAGL+ R+F S
Sbjct: 80 RGCACAEFLRG-----AARMGLPTDRIPQLDEVSGPLSELTGFRYVPAAGLVGLREFYGS 134
Query: 362 LAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASDSE 421
LA VF +TQY+RH+ PF+TPEPD IHE++GH LA FA + G A+ A ++
Sbjct: 135 LADGVFHATQYLRHHTVPFYTPEPDIIHEVVGHANALASDRFAALYRAAGEAARRAESAD 194
Query: 422 -IEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQP 480
++ +S V+WFT+EFG E+ +LKAYGA +LSS GE+ S +RP + A
Sbjct: 195 TLQFISKVFWFTLEFGTVYEDGELKAYGAGILSSYGEMAEFRS--VNVRPLDVAIMGTTD 252
Query: 481 YQDQEYQPIYYVAETFEDAKD 501
Y YQP+ Y A++F +D
Sbjct: 253 YDITRYQPVLYAADSFGQVED 273
>UniRef50_Q2S0V6 Cluster: Tryptophan 5-hydroxylase 1; n=1;
Salinibacter ruber DSM 13855|Rep: Tryptophan
5-hydroxylase 1 - Salinibacter ruber (strain DSM 13855)
Length = 278
Score = 157 bits (381), Expect = 7e-37
Identities = 83/235 (35%), Positives = 124/235 (52%), Gaps = 5/235 (2%)
Query: 275 GDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDV 334
GD I Y + ++ TWQ + ++ +P AC Y + L RIP L D+
Sbjct: 43 GDEIEYPDYPDEDHETWQILVERQMEQLPGRACEAYMRGQDVLGLEG----DRIPDLADL 98
Query: 335 SSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGH 394
S L + TG+ + GL+ ++F + L+ R F ST YVR +TP PDC H++ GH
Sbjct: 99 SRRLNEETGWEVANVPGLIHEKNFFSLLSQRKFPSTNYVRGREELDYTPAPDCFHDIFGH 158
Query: 395 IPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSS 454
+P+L P FA F Q G A+ A ++ +L +WFTVEFGL +E + + +GA ++SS
Sbjct: 159 MPMLTQPEFADFYQLYGQAAQNAEGADRPRLERFHWFTVEFGLIQEQGEKRIFGAGIVSS 218
Query: 455 IGELLHALSDKPELRPFEPAS-TSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVS 508
E+ HALS++ L PF+P Y+ Q +V ++FE D FR W S
Sbjct: 219 NEEVTHALSEEVTLHPFDPEHIVEKDDYEVYNLQEELFVLDSFEQLVDGFRDWTS 273
>UniRef50_UPI0000F1F407 Cluster: PREDICTED: similar to tryptophan
hydroxylase D1; n=7; Danio rerio|Rep: PREDICTED: similar
to tryptophan hydroxylase D1 - Danio rerio
Length = 488
Score = 147 bits (357), Expect = 6e-34
Identities = 67/89 (75%), Positives = 76/89 (85%)
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
RK TGFT+RP AG L+ RDFLA LAFRVF TQYVRH++ P +TPEPD HELLGH+PLL
Sbjct: 360 RKRTGFTIRPVAGYLSPRDFLAGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLL 419
Query: 399 ADPSFAQFSQEIGLASLGASDSEIEKLST 427
A+PSFAQFSQEIGLASLGASD I+KL+T
Sbjct: 420 AEPSFAQFSQEIGLASLGASDDSIQKLAT 448
>UniRef50_Q5ZS72 Cluster: Phenylalanine-4-hydroxylase; n=4;
Legionella pneumophila|Rep: Phenylalanine-4-hydroxylase
- Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 281
Score = 146 bits (353), Expect = 2e-33
Identities = 76/222 (34%), Positives = 119/222 (53%), Gaps = 5/222 (2%)
Query: 281 IAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRK 340
+ Y+ EN W +F L L+P AC E+ + + L IPQL +VS L+
Sbjct: 27 VDYSAQENRIWNILFERQLKLLPGRACDEFLSGLQTLGLNS----STIPQLPEVSERLKA 82
Query: 341 HTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLAD 400
TG+ + P A L++AR+F LA + F + ++R + EPD HEL GH P+L D
Sbjct: 83 KTGWQVAPVAALISAREFFELLAEKYFPAATFIRSEEELDYVQEPDIFHELFGHCPMLTD 142
Query: 401 PSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
+A+F + L + + L ++WFTVEFGL K + L+AYG +LSSI E ++
Sbjct: 143 RVYAEFVHDYACKVLTFPEQDWPLLQRMFWFTVEFGLIKTPKGLRAYGGGILSSISETVY 202
Query: 461 AL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKD 501
+ SD P F+P PY+ + QP+Y+V +++++ D
Sbjct: 203 CVESDIPVRILFDPVVAFRMPYRIDQLQPVYFVIDSYQNLYD 244
>UniRef50_Q1RGM5 Cluster: Phenylalanine-4-hydroxylase; n=1;
Rickettsia bellii RML369-C|Rep:
Phenylalanine-4-hydroxylase - Rickettsia bellii (strain
RML369-C)
Length = 246
Score = 142 bits (343), Expect = 3e-32
Identities = 76/221 (34%), Positives = 120/221 (54%), Gaps = 6/221 (2%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
+TE ++ W+ +FN +L+ A E EKL+ + RIP+ +++ L K T
Sbjct: 18 FTETDHEIWKTLFNRHTELLKNRATNEIVEGIEKLKICN----DRIPKFTELNRILMKET 73
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
F++ P G + F LA R F ST ++R + + EPD H++ GH+PLL +P
Sbjct: 74 NFSIIPVKGFIPEDLFFKFLAERKFPSTCFIRQPHQLDYLEEPDIFHDVFGHVPLLVNPV 133
Query: 403 FAQFSQEIGLASLGASDSEIEKL-STVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHA 461
FA F Q+ GL L A ++ + K S +YWFTVEFGL + N L+ YGA ++SS GE +++
Sbjct: 134 FADFMQQFGLKGLEAIEAGMLKFASALYWFTVEFGLIQSNNGLRIYGAGIISSKGESIYS 193
Query: 462 L-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKD 501
L S+ P F+ Y+ +Q Y+V ++F+ D
Sbjct: 194 LESEIPMRLEFDLNKVIKTEYETDSFQKTYFVIKSFQQLFD 234
>UniRef50_Q4THP6 Cluster: Chromosome undetermined SCAF2776, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF2776,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 218
Score = 139 bits (337), Expect = 2e-31
Identities = 85/214 (39%), Positives = 105/214 (49%), Gaps = 51/214 (23%)
Query: 223 PWFPRHASDLDNCNHLMTKYEPELDMNHP-------------------------GFADKD 257
PWFP S+LD C+H + Y ELD +HP GF D+
Sbjct: 5 PWFPMKISELDQCSHRVLMYGTELDADHPVSDPLEPPRSGCLPADRFPPSARRQGFKDQV 64
Query: 258 YRERRKQIAEIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKL 317
YR+RRK E+A YK+G PIP + YT E TW VF + L P HACREY L
Sbjct: 65 YRQRRKYFVEVAMNYKFGQPIPRVEYTPEEVRTWGVVFRELTKLYPTHACREYLKNLPLL 124
Query: 318 QAADIFVPHRIPQLEDVSSFLR--------------------------KHTGFTLRPAAG 351
+ +PQLEDVS FLR + +GFT+RP AG
Sbjct: 125 SKHCGYREDNVPQLEDVSLFLRGPLDVVRNSQSDKVAVTVTRGPWCVPERSGFTVRPVAG 184
Query: 352 LLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEP 385
L+ RDFLA LA+RVF TQY+RH+ P +TPEP
Sbjct: 185 YLSPRDFLAGLAYRVFNCTQYIRHSTDPLYTPEP 218
>UniRef50_Q1ISS1 Cluster: Phenylalanine 4-monooxygenase; n=1;
Acidobacteria bacterium Ellin345|Rep: Phenylalanine
4-monooxygenase - Acidobacteria bacterium (strain
Ellin345)
Length = 250
Score = 137 bits (331), Expect = 8e-31
Identities = 70/216 (32%), Positives = 118/216 (54%), Gaps = 5/216 (2%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
Y+++E+GTW+ ++ ++ + HAC+EY E L+ + R+P + D++ L+ T
Sbjct: 24 YSDVEHGTWKTLYERRMEQLSTHACKEY---LEGLRVLGMRA-ERMPVISDINKTLQTRT 79
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
+ L P +G L R F LA RVF T Y+R +S +TPEPD H++ GH+P+ A
Sbjct: 80 NWMLLPVSGFLPGRTFFDLLAARVFPVTTYIRKPDSLDYTPEPDIFHDIFGHVPMHAHKV 139
Query: 403 FAQFSQEIG-LASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHA 461
FA + Q +A +D++ E+L ++W+TVEFGL +E +K YG+ ++SS+ E +
Sbjct: 140 FADYLQAFAQIARQITNDADQERLGRLFWYTVEFGLIREGSDVKMYGSGVISSVKEGDNV 199
Query: 462 LSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFE 497
+ ++ F + E QP + E FE
Sbjct: 200 VHRGCKIHDFSLEEVLDTHVKVDELQPTLFAIENFE 235
>UniRef50_P43334 Cluster: Phenylalanine-4-hydroxylase; n=66;
Gammaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Pseudomonas aeruginosa
Length = 262
Score = 137 bits (331), Expect = 8e-31
Identities = 74/213 (34%), Positives = 113/213 (53%), Gaps = 6/213 (2%)
Query: 281 IAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPH-RIPQLEDVSSFLR 339
I Y E E+ W + L ++ AC+EY E+L +PH RIPQL++++ L+
Sbjct: 17 IHYPETEHQVWNTLITRQLKVIEGRACQEYLDGIEQLG-----LPHERIPQLDEINRVLQ 71
Query: 340 KHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLA 399
TG+ + L+ + F LA + F ++R + EPD HE+ GH PLL
Sbjct: 72 ATTGWRVARVPALIPFQTFFELLASQQFPVATFIRTPEELDYLQEPDIFHEIFGHCPLLT 131
Query: 400 DPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELL 459
+P FA+F+ G L AS E L+ +YW T+EFGL + +Q + YG +LSS E +
Sbjct: 132 NPWFAEFTHTYGKLGLKASKEERVFLARLYWMTIEFGLVETDQGKRIYGGGILSSPKETV 191
Query: 460 HALSDKPELRPFEPASTSVQPYQDQEYQPIYYV 492
++LSD+P + F P PY+ QP+Y+V
Sbjct: 192 YSLSDEPLHQAFNPLEAMRTPYRIDILQPLYFV 224
>UniRef50_A6FEK6 Cluster: Phenylalanine-4-hydroxylase; n=1;
Moritella sp. PE36|Rep: Phenylalanine-4-hydroxylase -
Moritella sp. PE36
Length = 272
Score = 134 bits (325), Expect = 4e-30
Identities = 75/219 (34%), Positives = 112/219 (51%), Gaps = 5/219 (2%)
Query: 281 IAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRK 340
I Y++ E+ TW ++N +++ AC E+ A E LQ RIPQL D++ L+K
Sbjct: 24 INYSDEEHNTWATLYNRQTEIIKDRACDEFIAGIELLQMG----ADRIPQLPDINRKLKK 79
Query: 341 HTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLAD 400
TG+ + L+ F LA + F + ++R + EPD HEL GH PLL +
Sbjct: 80 LTGWQVENVPALIGFERFFELLATKRFPAATFIRTKADIDYIQEPDIFHELFGHCPLLTN 139
Query: 401 PSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
++A FSQ G L A ++ L+ +YWFT+EFGL + Q LK +G +LSS E +
Sbjct: 140 QAYADFSQHYGELGLKADKADRPMLARLYWFTIEFGLMQSQQGLKIFGGGILSSKQETCY 199
Query: 461 AL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
+L SD P +P + Y+ E Q Y+V D
Sbjct: 200 SLDSDIPNRQPLQVIEAFRTHYRIDELQKNYFVINQLSD 238
>UniRef50_Q124D5 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=8; Burkholderiales|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 292
Score = 130 bits (313), Expect = 1e-28
Identities = 81/230 (35%), Positives = 119/230 (51%), Gaps = 7/230 (3%)
Query: 274 YGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLED 333
Y P AYT ++ + R++ L+P AC E+ AA L A + RIP+ E+
Sbjct: 35 YTCPQNYAAYTAADHDIYHRLYQRQSALVPGLACDEFIAALPLLGAKE-----RIPRFEE 89
Query: 334 VSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLG 393
++ L K T + + GL+ F LA R F T ++R + EPD H+L G
Sbjct: 90 INERLYKATRWEIVAVPGLIPEVPFFTLLANRKFPVTDWLRTPAEFDYIVEPDVFHDLFG 149
Query: 394 HIPLLADPSFAQFSQEIGLASLGA-SDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALL 452
H+PLL +P FA Q G L A + E+LS +YW+TVEFGL ++ L+AYGA +L
Sbjct: 150 HVPLLFNPVFADHMQAYGAGGLKAHALGACEQLSRLYWYTVEFGLIRQANGLRAYGAGIL 209
Query: 453 SSIGELLHAL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKD 501
SS GEL +A+ S +P+ T Y+ YQ Y+V ++F+ D
Sbjct: 210 SSSGELAYAVQSPEPQRIALNLLRTMRTRYKIDSYQQTYFVIDSFQQLFD 259
>UniRef50_Q9KLB8 Cluster: Phenylalanine-4-hydroxylase; n=19;
Vibrionaceae|Rep: Phenylalanine-4-hydroxylase - Vibrio
cholerae
Length = 289
Score = 128 bits (308), Expect = 5e-28
Identities = 71/213 (33%), Positives = 105/213 (49%), Gaps = 5/213 (2%)
Query: 281 IAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRK 340
I + + E+ W + +++ AC+ Y L R+PQL +++ L++
Sbjct: 40 IDWDQDEHAVWHELITRQQEVVKTRACQAYLDGLNMLNLPT----DRLPQLPEINRVLQR 95
Query: 341 HTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLAD 400
TG+ + P L++ F A LA + F ++R + EPD HE+ GH +L
Sbjct: 96 ETGWQVEPVPALISFDRFFALLADKKFPVATFLRRREEFDYLQEPDFFHEVYGHCAMLTH 155
Query: 401 PSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
P FA F+ G A+ E L+ +YWFTVEFGL +E Q K YG +LSS GE L+
Sbjct: 156 PDFAAFTHVYGQLGAKATPKERSYLARLYWFTVEFGLVQEQGQTKIYGGGILSSPGETLY 215
Query: 461 AL-SDKPELRPFEPASTSVQPYQDQEYQPIYYV 492
A S P+ PF+ PY+ QPIYYV
Sbjct: 216 ASESTIPKREPFDIMQVLRTPYRIDIMQPIYYV 248
>UniRef50_Q1VW50 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=1; Psychroflexus torquis ATCC 700755|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Psychroflexus torquis ATCC 700755
Length = 242
Score = 125 bits (301), Expect = 4e-27
Identities = 70/224 (31%), Positives = 115/224 (51%), Gaps = 4/224 (1%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT+ + W +FN + +P A + Y A E + + + IP E ++S+ + T
Sbjct: 7 YTKDDLWVWNTLFNRQKENIPGKASKSYIDALEHM--SPVLNADEIPDFEKINSWFKTET 64
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
+ L+ GL+ +F LA R F S+ ++R +S + EPD H++ GH+PLL+DP
Sbjct: 65 QWELQVVPGLIPVEEFFKLLAERKFCSSTWLRSKDSLDYLEEPDVFHDIFGHVPLLSDPV 124
Query: 403 FAQFSQEIG-LASLGASDSE-IEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
F++F E G L D+E + +L +YWFT+EFG+ KE +++YGA +LSS GE
Sbjct: 125 FSEFVCEFGKLGCQFLGDTEKLIQLQRLYWFTIEFGVIKEQGSIQSYGAGILSSSGETNQ 184
Query: 461 ALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFR 504
K + + + ++ Q YYV +FE D +
Sbjct: 185 IHEQKANFIDYSIQAIIEKEFRTDIMQEDYYVISSFEILFDSLK 228
>UniRef50_Q98D72 Cluster: Phenylalanine-4-hydroxylase; n=1;
Mesorhizobium loti|Rep: Phenylalanine-4-hydroxylase -
Rhizobium loti (Mesorhizobium loti)
Length = 275
Score = 124 bits (299), Expect = 6e-27
Identities = 79/229 (34%), Positives = 116/229 (50%), Gaps = 16/229 (6%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
Y++ E W+ + + L K A Y EKL D RIP EDVS+ LRK T
Sbjct: 34 YSDEEQAVWRTLCDRQTKLTRKLAHHSYLDGVEKLGLLD-----RIPDFEDVSTKLRKLT 88
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ + GL+ A F LA R F T ++R + EPD H+ GH+P+L+ P
Sbjct: 89 GWEIIAVPGLIPAAPFFDHLANRRFPVTNWLRTRQELDYIVEPDMFHDFFGHVPVLSQPV 148
Query: 403 FAQFSQEIG-----LASLGASDSEIEKLSTVYWFTVEFGLCKE-NQQLKAYGAALLSSIG 456
FA F Q G + +LG E ++ +YW+T E+GL +E Q LKA+GA L+SS
Sbjct: 149 FADFMQMYGKKAGDIIALGGD----EMITRLYWYTAEYGLVQEAGQPLKAFGAGLMSSFT 204
Query: 457 ELLHALSDKPELR-PFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFR 504
EL A+ K PF+ + Y+ ++Q Y+V +F+ +D F+
Sbjct: 205 ELQFAVEGKDAHHVPFDLETVMRTGYEIDKFQRAYFVLPSFDALRDAFQ 253
>UniRef50_Q2K9E9 Cluster: Phenylalanine-4-hydroxylase protein; n=2;
Rhizobium|Rep: Phenylalanine-4-hydroxylase protein -
Rhizobium etli (strain CFN 42 / ATCC 51251)
Length = 263
Score = 121 bits (292), Expect = 4e-26
Identities = 73/233 (31%), Positives = 108/233 (46%), Gaps = 5/233 (2%)
Query: 267 EIAFAYKYGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPH 326
E ++ K P YT E+ W ++ + L+ AC+EY + L P
Sbjct: 4 ESSYTAKLPGPDGLYDYTPEEDAIWGELYRRQMKLLADKACQEYLDGVKLLGLR----PE 59
Query: 327 RIPQLEDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPD 386
++PQL DV+ L + TGF + L+ F L+ F ++R + EPD
Sbjct: 60 KVPQLLDVNRRLNETTGFGVEGVPALIPPSRFYELLSQGKFPLATFLRRREHIDYIEEPD 119
Query: 387 CIHELLGHIPLLADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKA 446
HE+ GH PLL + S+A F + G ++ L ++WFTVEFGL Q +
Sbjct: 120 LFHEVFGHCPLLTNQSYANFVRHFGETAMRLGKGYSWHLFRIFWFTVEFGLINTPQGRRC 179
Query: 447 YGAALLSSIGELLHALSDKP-ELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
+GA ++SS E A E RPF+ S PY+ QPIYYV ++F D
Sbjct: 180 FGAGIVSSPSEAKAATEGTACEFRPFDLLSVLRTPYRIDILQPIYYVIDSFAD 232
>UniRef50_Q0C2D1 Cluster: Phenylalanine-4-hydroxylase; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Phenylalanine-4-hydroxylase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 293
Score = 118 bits (285), Expect = 3e-25
Identities = 71/217 (32%), Positives = 107/217 (49%), Gaps = 6/217 (2%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
Y+ E+ W R+F ++ A + A KL+ + P IP + +S L K T
Sbjct: 28 YSPAEHDRWDRLFRRQKEIATGRASKVALDAMHKLELS----PSGIPHMGRLSDKLEKIT 83
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ + P A L+ F LA R F + ++R + EPD H++ GH+P+LADP
Sbjct: 84 GWRVVPVAELVPDEVFFDHLANRRFPAGAFIRPEEEFDYLQEPDIFHDIFGHVPMLADPV 143
Query: 403 FAQFSQEIGLASLGASD-SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHA 461
FA F + G A ++ L+ +YW+TVEFGL +E L+ YGA +LSS E + A
Sbjct: 144 FADFMEAYGKGGQRAMRLGQLHNLARLYWYTVEFGLIQEEDGLRIYGAGILSSPHETVFA 203
Query: 462 LSD-KPELRPFEPASTSVQPYQDQEYQPIYYVAETFE 497
L D P F+ Y ++Q Y+V +FE
Sbjct: 204 LEDASPNRIGFDLQRLMRTKYIIDDFQQTYFVIPSFE 240
>UniRef50_Q0ANJ2 Cluster: Phenylalanine-4-hydroxylase; n=2;
Alphaproteobacteria|Rep: Phenylalanine-4-hydroxylase -
Maricaulis maris (strain MCS10)
Length = 293
Score = 118 bits (284), Expect = 4e-25
Identities = 66/218 (30%), Positives = 112/218 (51%), Gaps = 6/218 (2%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT E+ W ++ + ++ A E+ A + L + IP V+ L K T
Sbjct: 26 YTAGEHAIWTTLYERQMGVLKGRAAPEHFAGLDMLNLNE----GGIPDFRRVNEKLEKLT 81
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+T+ GL+ +DF LA R F S +++R + + PEPD H++ GH+PLL P
Sbjct: 82 GWTVVTVPGLIPEKDFYEHLANRRFVSGRFIRDGETLDYLPEPDIFHDVFGHVPLLTQPV 141
Query: 403 FAQFSQEIGLASLGASDSE-IEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHA 461
FA + Q G L + + + I+ ++ +YW+TVEFGL + + YGA ++SS E + +
Sbjct: 142 FADYMQAYGKGGLRSLEFDAIKHMARLYWYTVEFGLINTPEGRRIYGAGIVSSRTESIFS 201
Query: 462 LSDK-PELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
L K P F+ Y+ ++Q Y+V +++E+
Sbjct: 202 LEGKSPNRLHFDLERIMQTDYRYDDFQQSYFVIDSYEE 239
>UniRef50_A7CCY2 Cluster: Phenylalanine-4-hydroxylase; n=8;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia pickettii 12D
Length = 349
Score = 118 bits (284), Expect = 4e-25
Identities = 66/228 (28%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Query: 279 PSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFL 338
P YT ++ TW+ +++ L+P C E+ L + +P + ++ L
Sbjct: 84 PVHRYTAADHATWRTLYDRQEALLPGRVCDEFLQGLSTLGMSR----DAVPSFDQLNETL 139
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
+ TG+ + GL+ F LA R F ++ ++R + + EPDC H++ GH+PLL
Sbjct: 140 MRATGWQIVAVPGLVPDEVFFDHLANRRFPASWWMRRPDQLDYLQEPDCFHDIFGHVPLL 199
Query: 399 ADPSFAQFSQEIGLASLGASD-SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGE 457
+P FA + + G L A+ +++ L+ +YW+TVEFGL + L+ YGA ++SS E
Sbjct: 200 INPIFADYMEAYGKGGLKAARLGQLDMLARLYWYTVEFGLIRTPAGLRIYGAGIVSSKSE 259
Query: 458 LLHAL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFR 504
++AL S P F+ Y+ +Q Y+ ++FE D R
Sbjct: 260 SVYALDSASPNRIGFDVRRIMRTRYRIDTFQKTYFTIDSFEQLFDATR 307
>UniRef50_A3HZI9 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Flexibacteraceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Algoriphagus sp. PR1
Length = 259
Score = 117 bits (281), Expect = 1e-24
Identities = 69/217 (31%), Positives = 110/217 (50%), Gaps = 6/217 (2%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT + W+ +F + +PK A + Y E + F RI ED++ L K T
Sbjct: 25 YTSEDFKVWKILFERQMPNLPKAASKAYLDGVEIVG----FSADRIANFEDLNQILAKTT 80
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ ++ GL+ F L R F S+ ++R + EPD H+ H+P+L +
Sbjct: 81 GWEVQVVPGLIDDDLFFGLLNNRRFPSSTWLRKMEQLDYLQEPDMFHDAFAHMPMLTNQP 140
Query: 403 FAQFSQEI-GLASLGASDS-EIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
+ F +++ G+A ++ I+ LS +YWFT+EFGL KE +LK YGA +LSS GE
Sbjct: 141 YVDFLEKLSGIALKHINNPWAIQLLSRIYWFTIEFGLIKEGGELKIYGAGILSSAGETKF 200
Query: 461 ALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFE 497
+LS++P ++ Q Y +Q Y+V E +E
Sbjct: 201 SLSNEPNHIDYDVRRILNQEYWKDRFQDKYFVIENYE 237
>UniRef50_Q5S6Z8 Cluster: Henna; n=1; Bicyclus anynana|Rep: Henna -
Bicyclus anynana (squinting bush brown)
Length = 125
Score = 116 bits (279), Expect = 2e-24
Identities = 53/102 (51%), Positives = 74/102 (72%)
Query: 444 LKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKF 503
LKA+GA LLSS GEL + LSDKPELR EP+ T Q Y EYQP+Y+VA++FE AK+K
Sbjct: 1 LKAFGAGLLSSFGELQYCLSDKPELRESEPSVTGEQKYPITEYQPVYFVAQSFESAKEKM 60
Query: 504 RRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEM 545
++ T+ R F VR+NP+T+ +++LDS ++ L+ Q+ TEM
Sbjct: 61 IKFAQTIPREFGVRYNPYTQSIDILDSPRQMTDLLKQIRTEM 102
>UniRef50_Q8XU39 Cluster: Phenylalanine-4-hydroxylase; n=40;
Proteobacteria|Rep: Phenylalanine-4-hydroxylase -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 313
Score = 116 bits (278), Expect = 2e-24
Identities = 68/228 (29%), Positives = 114/228 (50%), Gaps = 6/228 (2%)
Query: 279 PSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFL 338
P YT ++ TW+ +++ L+P AC E+ L + +P + ++ L
Sbjct: 48 PVHRYTAADHATWRTLYDRQEALLPGRACDEFLQGLSTLGMSR----EGVPSFDRLNETL 103
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
+ TG+ + GL+ F LA R F ++ ++R + + EPD H++ GH+PLL
Sbjct: 104 MRATGWQIVAVPGLVPDEVFFEHLANRRFPASWWMRRPDQLDYLQEPDGFHDIFGHVPLL 163
Query: 399 ADPSFAQFSQEIGLASLGASD-SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGE 457
+P FA + Q G L A+ ++ L+ +YW+TVEFGL + L+ YGA ++SS E
Sbjct: 164 INPVFADYMQAYGQGGLKAARLGALDMLARLYWYTVEFGLIRTPAGLRIYGAGIVSSKSE 223
Query: 458 LLHAL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFR 504
++AL S P F+ Y+ +Q Y+V ++FE D R
Sbjct: 224 SVYALDSASPNRIGFDVHRIMRTRYRIDTFQKTYFVIDSFEQLFDATR 271
>UniRef50_Q01Z53 Cluster: Aromatic amino acid hydroxylase; n=1;
Solibacter usitatus Ellin6076|Rep: Aromatic amino acid
hydroxylase - Solibacter usitatus (strain Ellin6076)
Length = 306
Score = 113 bits (271), Expect = 2e-23
Identities = 76/250 (30%), Positives = 123/250 (49%), Gaps = 26/250 (10%)
Query: 279 PSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPH-RIPQLEDVSSF 337
P Y++ + WQ++F + ++A + E L+ +PH R+P+L DV+
Sbjct: 32 PYELYSKENHEAWQKLFKRIHTRWERYANDHFLRGVEALE-----LPHDRVPRLTDVNRR 86
Query: 338 LRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPL 397
L+ TGF +P +G + F L R F +T +R + + PEPD H++ GH+P+
Sbjct: 87 LQPLTGFQAKPVSGYVPGFLFFDCLRRREFPTTITIRPADRMDYLPEPDIFHDVAGHVPM 146
Query: 398 LADPSFAQFSQEIGLASLGAS----------------DSEIEKLSTVYWFTVEFGLCKEN 441
+ FA G ++ A+ S + +S +WFTVEFGL +
Sbjct: 147 HTERQFADTLVRFGDCAVTAARITAEVKDPAKRVRRLTSIMRAMSRFFWFTVEFGLMRGT 206
Query: 442 QQLKAYGAALLSSIGELLHAL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFE--- 497
+ AYG+ LLSS GEL HA+ SD+ + P + Q + YQPI +V ++FE
Sbjct: 207 KGTVAYGSGLLSSYGELEHAIESDEVQRYPIQLEWVINQVAEIDHYQPILFVVDSFEHLF 266
Query: 498 DAKDKFRRWV 507
D D+F +W+
Sbjct: 267 DLVDEFEKWM 276
>UniRef50_A3UHY3 Cluster: Phenylalanine-4-hydroxylase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep:
Phenylalanine-4-hydroxylase - Oceanicaulis alexandrii
HTCC2633
Length = 370
Score = 111 bits (268), Expect = 4e-23
Identities = 71/242 (29%), Positives = 117/242 (48%), Gaps = 30/242 (12%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT E+ W+ +F ++P AC+++ FE+L+ +F IP +D+++ L+ T
Sbjct: 65 YTPAEHARWRLLFENQRKMLPGRACKDFMEGFEQLE--HLF-KDGIPSFDDINAILKPAT 121
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNN-------------SP---------- 379
G+T+ P L+ F L R F + ++R N +P
Sbjct: 122 GWTVVPVPELIPDNIFFWHLENRRFPAGVFIRGGNPKTKKVKEANEGRAPEFVEYTAVED 181
Query: 380 --FHTPEPDCIHELLGHIPLLADPSFAQFSQEIGLASLGASD-SEIEKLSTVYWFTVEFG 436
F+ EPD H++ GH+P+L +P FA + Q G A + + ++ +VYW+TVEFG
Sbjct: 182 DLFYLQEPDTFHDIFGHVPMLMNPFFADYIQAYGAGGRRAIEYNRLKNFGSVYWYTVEFG 241
Query: 437 LCKENQQLKAYGAALLSSIGELLHAL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAET 495
L E +L+ YGA +LSS E L +L SD P P Y ++Q Y+V ++
Sbjct: 242 LILEEGELRVYGAGILSSPDETLFSLYSDSPHRIKMVPERVMRTDYVISDFQETYFVVDS 301
Query: 496 FE 497
+
Sbjct: 302 IK 303
>UniRef50_A5P8R6 Cluster: Phenylalanine-4-hydroxylase; n=4;
Sphingomonadales|Rep: Phenylalanine-4-hydroxylase -
Erythrobacter sp. SD-21
Length = 313
Score = 111 bits (267), Expect = 5e-23
Identities = 64/219 (29%), Positives = 110/219 (50%), Gaps = 7/219 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
Y ++ W +F ++++P A + EKL +P+ +S L K T
Sbjct: 44 YDSEDDAIWNDLFKRQMEMLPGRAATAFMEGTEKLDLGR----GGVPEFGKLSEELDKLT 99
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+++ P L+ F LA R F + ++R + + EPD H++ GH+P+L DP
Sbjct: 100 GWSVVPVPMLIPDHVFFWHLANRRFPAGNFIRTRETFDYIQEPDVFHDVFGHVPMLTDPV 159
Query: 403 FAQFSQEIGLASLGASD-SEIEKLSTVYWFTVEFGLCKENQ-QLKAYGAALLSSIGELLH 460
+A + QE G A A + ++ L ++YW+TVEFGL +E ++AYGA +LS E+++
Sbjct: 160 YADYMQEYGKAGWKAMRYNRLKALGSLYWYTVEFGLIEEKPGDIRAYGAGILSGPTEVVY 219
Query: 461 AL-SDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
++ ++ P Y + QP Y+V +FED
Sbjct: 220 SVEAESPNRIMLNVDRVMRTDYVISDLQPTYFVIPSFED 258
>UniRef50_Q0LGC2 Cluster: Aromatic amino acid hydroxylase; n=3;
Chloroflexi (class)|Rep: Aromatic amino acid hydroxylase
- Herpetosiphon aurantiacus ATCC 23779
Length = 247
Score = 110 bits (265), Expect = 8e-23
Identities = 68/211 (32%), Positives = 104/211 (49%), Gaps = 9/211 (4%)
Query: 281 IAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRK 340
+ Y + ++ TW ++ + L +HAC+ + + L +P + VS +L
Sbjct: 11 LEYPQEDHDTWAALWQRQMPLAQQHACKLFLEGIDILNLDRTHLPDPLA----VSDYLNT 66
Query: 341 HTGFTLRPAAGL-LTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLA 399
TG+ L A L ++ +A R F T Y+R + TP PD HE GH+P
Sbjct: 67 LTGWALGDAQNAYLGPTEWFEHIAERRFPVTNYIRRPHELEFTPLPDLFHEYFGHLPAFT 126
Query: 400 DPSFAQFSQEIGLASLGASDSEIEK-LSTVYWFTVEFGLCKENQQLKAYGAALLSSIGEL 458
+ FA +Q G L A D + ++ ++WF+ EFGL +EN +LK GA LLSS GEL
Sbjct: 127 NREFADIAQLFGPLYLSAKDERQQLGIARIWWFSTEFGLLRENGELKVLGAGLLSSPGEL 186
Query: 459 LHALSDKPELRPFE---PASTSVQPYQDQEY 486
LHAL+ + F+ A T+ PY E+
Sbjct: 187 LHALNPETPRYEFDIERVADTASAPYGYHEH 217
>UniRef50_Q1GTB6 Cluster: Phenylalanine-4-hydroxylase, monomeric
form; n=2; Sphingomonadaceae|Rep:
Phenylalanine-4-hydroxylase, monomeric form -
Sphingopyxis alaskensis (Sphingomonas alaskensis)
Length = 290
Score = 102 bits (245), Expect = 2e-20
Identities = 63/218 (28%), Positives = 109/218 (50%), Gaps = 6/218 (2%)
Query: 282 AYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKH 341
A+T ++ TW+ +F+ M +ACR + L+ + +P ++++ L+
Sbjct: 26 AFTPEQHRTWRTLFDRQSAAMGGYACRAFLDGLGLLRR----LRPGVPDFAELNALLKPA 81
Query: 342 TGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADP 401
+G+ + G + F LA R F + +VR ++ EPD H++ GH+P+LA+P
Sbjct: 82 SGWEVVAVPGWIPNAPFFEHLANRRFPAANFVRPPEQIAYSEEPDMFHDIFGHVPMLANP 141
Query: 402 SFAQFSQEIGLASLGA-SDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLH 460
+F F G A L A S + L ++ +TVEFGL E +L+A+G LLSS+ E
Sbjct: 142 AFGDFLVAYGEAGLRAESLGASDYLGRLWLYTVEFGLVVEEGELRAFGGGLLSSLAETAF 201
Query: 461 ALSDKPELRPFEPASTSVQP-YQDQEYQPIYYVAETFE 497
AL+ R + +++ Y +Q Y+V E F+
Sbjct: 202 ALTAPEPRRIWLDVERAMRTRYHFDAFQQTYFVVEGFD 239
>UniRef50_Q11QP8 Cluster: Phenylalanine-4-hydroxylase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep:
Phenylalanine-4-hydroxylase - Cytophaga hutchinsonii
(strain ATCC 33406 / NCIMB 9469)
Length = 246
Score = 90.2 bits (214), Expect = 1e-16
Identities = 56/218 (25%), Positives = 104/218 (47%), Gaps = 7/218 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YTE EN W ++ +L+ + A + R+P +E+++ L KHT
Sbjct: 15 YTEEENKIWATAYSRILNFLGDVADESVMIGIRTIGLPG----DRVPNVEEINEHLAKHT 70
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRH-NNSPFHTPEPDCIHELLGHIPLLADP 401
+ + P ++ F++ LA +++ +VR + E D H++ GH LL P
Sbjct: 71 DWRIVPLEDMVDDTQFISMLADKLYPCRTWVRSIDQVDKMEDEYDIFHDVFGHTSLLYIP 130
Query: 402 SFAQFSQEIG-LASLGASDSE-IEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELL 459
++ + +++G LA +D + I L VYW T+++GL + N+ L+ YGA +++S E
Sbjct: 131 TYCLYLEQLGELALTYINDPKAILYLKRVYWHTIQYGLIEANKSLRIYGAHMITSRNEAS 190
Query: 460 HALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFE 497
+AL+ + PY +Q Y+V ++E
Sbjct: 191 YALNAGVPKYDHNVSIIMDTPYVKNHFQEKYFVISSYE 228
>UniRef50_Q9Z6L3 Cluster: Probable aromatic amino acid hydroxylase;
n=2; Chlamydophila pneumoniae|Rep: Probable aromatic
amino acid hydroxylase - Chlamydia pneumoniae
(Chlamydophila pneumoniae)
Length = 362
Score = 84.2 bits (199), Expect = 8e-15
Identities = 61/224 (27%), Positives = 98/224 (43%), Gaps = 21/224 (9%)
Query: 291 WQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHTGFTLRPAA 350
W R+ ++ L + R + E F+ H+ V F T F+ P +
Sbjct: 107 WYRLLSSRFSLWKSYCPRFFLDYLEAFGLLSDFLDHQA-----VIKFFELETHFSYYPVS 161
Query: 351 GLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPSFAQFSQEI 410
G + +L+ L R F +R + + PD IH+LLGH+P L PSF++F +
Sbjct: 162 GFVAPHQYLSLLQDRYFPIASVMRTLDKDNFSLTPDLIHDLLGHVPWLLHPSFSEFFINM 221
Query: 411 G------LASLGASDSEIEKLSTV----------YWFTVEFGLCKENQQLKAYGAALLSS 454
G + + A S+ +++ T+ +WFTVE GL + ++ KAYGA L+SS
Sbjct: 222 GRLFTKVIEKVQALPSKKQRIQTLQSNLIAIVRCFWFTVESGLIENHEGRKAYGAVLISS 281
Query: 455 IGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
EL HA D + P E P+ Q + F++
Sbjct: 282 PQELGHAFIDNVRVLPLELDQIIRLPFNTSTPQETLFSIRHFDE 325
>UniRef50_Q255G4 Cluster: Aromatic amino acid hyroxylase
biopterin-dependent; n=3; Chlamydophila|Rep: Aromatic
amino acid hyroxylase biopterin-dependent -
Chlamydophila felis (strain Fe/C-56)
Length = 279
Score = 83.4 bits (197), Expect = 1e-14
Identities = 54/186 (29%), Positives = 85/186 (45%), Gaps = 16/186 (8%)
Query: 332 EDVSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHEL 391
+ ++S + +GFTL P G L+ ++L L+ + F VR + PD IH+L
Sbjct: 53 DHINSVISSQSGFTLSPTQGYLSPHNYLFELSQKRFPIATNVRSLEEDGFSTLPDLIHDL 112
Query: 392 LGHIPLLADPSFAQFSQEIG---LASLGAS-------------DSEIEKLSTVYWFTVEF 435
HIP L P F F +G + S+ + +S +S +WFTVE
Sbjct: 113 FCHIPWLLHPEFVNFFSTMGELFVKSIKRAKEIYPIEDQPRILNSNALAISRCFWFTVES 172
Query: 436 GLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAET 495
GL +E + KAYGAA+LSS +L H ++ + PF+ +P Q ++
Sbjct: 173 GLIEEQGKRKAYGAAVLSSTEQLSHTFNNNVFVSPFKTEHIIQRPCNPNAIQTTLFIIRD 232
Query: 496 FEDAKD 501
F + D
Sbjct: 233 FSELND 238
>UniRef50_Q9AG78 Cluster: Amino acid hydroxylase; n=1; Streptomyces
verticillus|Rep: Amino acid hydroxylase - Streptomyces
verticillus
Length = 244
Score = 82.2 bits (194), Expect = 3e-14
Identities = 61/227 (26%), Positives = 91/227 (40%), Gaps = 6/227 (2%)
Query: 274 YGDPIPSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLED 333
+G P Y ++ W+ ++ +L+P A Y E L + H +P L
Sbjct: 4 HGVPPVQEPYGPVDQEVWRHLYRQQAELVPAAAPPLY---LEGLALLGLPTDH-VPDLGQ 59
Query: 334 VSSFLRKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLG 393
V+ L +G+T GL+ +F L R F T +R PD H+L G
Sbjct: 60 VNERLSAVSGWTCVAVDGLVKGPEFFDMLLHRRFPVTSRMRAPEELRFARLPDLFHDLFG 119
Query: 394 HIPLLADPSFAQFSQEIGLASLGASD--SEIEKLSTVYWFTVEFGLCKENQQLKAYGAAL 451
H P LA A QE G + + + L + W T+E GL + L+A G A+
Sbjct: 120 HGPYLAHARTADLYQEFGRIGVRCAGRPEDFALLQGILWSTLETGLIRTPGGLRALGGAI 179
Query: 452 LSSIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFED 498
LSS E+ L + PF+P Y Q Y+ E E+
Sbjct: 180 LSSADEIRQCLDPACPVEPFDPEVVRFATYDILRLQSRYFAVEDLEE 226
>UniRef50_Q81LM9 Cluster: Phenylalanine-4-hydroxylase, putative;
n=10; Bacillus cereus group|Rep:
Phenylalanine-4-hydroxylase, putative - Bacillus
anthracis
Length = 584
Score = 72.5 bits (170), Expect = 3e-11
Identities = 34/92 (36%), Positives = 54/92 (58%)
Query: 420 SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQ 479
SE E++S ++W+TVE+GL + K YGA LLSS+GE H L+D E PF + +
Sbjct: 200 SEAEQISRLFWWTVEYGLIGDIDNPKIYGAGLLSSVGESKHCLTDAVEKVPFSIEACTST 259
Query: 480 PYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
Y + QP +V ++FE+ + ++ TM+
Sbjct: 260 TYDVTKMQPQLFVCKSFEELTEALEKFAETMA 291
Score = 48.0 bits (109), Expect = 7e-04
Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 5/129 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT + + W+ + + A + A LQ++ I + IP++E+++ L +
Sbjct: 23 YTPVNHAVWRYIMRQNHSFLKDVA---HPAYVNGLQSSGINI-EAIPKVEEMNECLAS-S 77
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ GL+ F + +R + +TP PD +HE GH P+L DP+
Sbjct: 78 GWGAVTIDGLIPGVAFFDFQGHGLLPIATDIRKVENIEYTPAPDIVHEAAGHAPILLDPT 137
Query: 403 FAQFSQEIG 411
+A++ + G
Sbjct: 138 YAKYVKRFG 146
>UniRef50_Q41AV6 Cluster: Aromatic amino acid hydroxylase; n=1;
Exiguobacterium sibiricum 255-15|Rep: Aromatic amino
acid hydroxylase - Exiguobacterium sibiricum 255-15
Length = 548
Score = 66.9 bits (156), Expect = 1e-09
Identities = 33/92 (35%), Positives = 48/92 (52%)
Query: 420 SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQ 479
SE ++S ++W+TVEFGL + + YGA LLSS+GE H L+D PF A
Sbjct: 199 SEANEISRLFWWTVEFGLIGDLDNPQIYGAGLLSSVGESRHCLTDAVVKHPFSLAKALAT 258
Query: 480 PYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
+ Q +V E+FE ++ + TMS
Sbjct: 259 KHDVTSMQKELFVCESFEQLREALEEFAQTMS 290
Score = 54.0 bits (124), Expect = 1e-05
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 5/129 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT ++ W+ V L + A + A E L A+ I P RIP + ++++ L +
Sbjct: 22 YTPTDHAVWRYVMRLNLKTLQDTA---HPAYLEGLAASGIS-PERIPDVREMTANLSRG- 76
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ GL+ F + +R ++ +TP PD +HE GH P+L +P+
Sbjct: 77 GWGTVAVDGLIPGVAFFDFQGHGLLPIATDIRKVDNILYTPAPDILHEAAGHAPILMNPT 136
Query: 403 FAQFSQEIG 411
+A+F + G
Sbjct: 137 YAEFVRRFG 145
>UniRef50_Q6MHK4 Cluster: Putative uncharacterized protein; n=1;
Bdellovibrio bacteriovorus|Rep: Putative uncharacterized
protein - Bdellovibrio bacteriovorus
Length = 580
Score = 63.7 bits (148), Expect = 1e-08
Identities = 36/127 (28%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT ++ W+ V + + KHA Y K DI RIP++EDVS +++
Sbjct: 22 YTPVDQAVWRYVLRQLKAFLSKHAHECYVEGLNKT-GIDI---ERIPRIEDVSKKIQEF- 76
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ P +G + F+ + V +R + +TP PD +HE GH P+L P
Sbjct: 77 GWRALPVSGFIPPAAFMELQSLGVLPIASDMRTLDHLLYTPAPDIVHEAAGHAPILIHPE 136
Query: 403 FAQFSQE 409
F+ + ++
Sbjct: 137 FSDYLRQ 143
Score = 50.0 bits (114), Expect = 2e-04
Identities = 30/78 (38%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 420 SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQ 479
SE +LS + W+T E+GL E K +GA LLSS+GE LS K + P
Sbjct: 199 SEASELSRMNWWTAEYGLIGELDNPKIFGAGLLSSVGESKWCLSQKVKKIPLTVDCIKTS 258
Query: 480 PYQDQEYQPIYYVAETFE 497
Y E QP +VA+ F+
Sbjct: 259 -YDITEPQPQLFVAKDFK 275
>UniRef50_A6CNR8 Cluster: Phenylalanine 4-monooxygenase; n=1;
Bacillus sp. SG-1|Rep: Phenylalanine 4-monooxygenase -
Bacillus sp. SG-1
Length = 642
Score = 61.3 bits (142), Expect = 7e-08
Identities = 32/93 (34%), Positives = 52/93 (55%)
Query: 419 DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSV 478
+SE E++S ++W+TVEFGL + ++ YGA LLSS+GE LSD+ + PF
Sbjct: 264 NSEAEQISRLFWWTVEFGLIGKVEKPMVYGAGLLSSVGESKACLSDQVKKIPFSIEECIK 323
Query: 479 QPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
Y Q +V E+FE+ + + ++M+
Sbjct: 324 TSYDVTTMQKQLFVCESFEELIEAVEEFSASMA 356
Score = 50.4 bits (115), Expect = 1e-04
Identities = 43/157 (27%), Positives = 75/157 (47%), Gaps = 13/157 (8%)
Query: 282 AYTEIENGTWQRVFNTVLDLMPKHACREYKA--AFEK-LQAADIFVPHRIPQLEDVSSFL 338
AYT + + W+ V + HA E +A AF K L+ + I + +IP++ +++ L
Sbjct: 87 AYTPVNHAVWRYV------MRQNHAFLEDRAHPAFLKGLKGSGIAI-EKIPRVSEMNEAL 139
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
+ G+ GL+ F A + +R ++ +TP PD +HE GH P+L
Sbjct: 140 GR-IGWGAVIVDGLIPGTAFFDLQAHGLLPIATDIRKVSNIEYTPAPDILHEAAGHAPIL 198
Query: 399 ADPSFAQFSQEIGL--ASLGASDSEIEKLSTVYWFTV 433
D ++++F ++IG A A+ E E V T+
Sbjct: 199 FDSTYSEFVKKIGAVGAKAFATKEEHEAFEAVRNLTI 235
>UniRef50_A6E752 Cluster: Phenylalanine-4-hydroxylase; n=1;
Pedobacter sp. BAL39|Rep: Phenylalanine-4-hydroxylase -
Pedobacter sp. BAL39
Length = 594
Score = 60.9 bits (141), Expect = 9e-08
Identities = 36/93 (38%), Positives = 54/93 (58%), Gaps = 3/93 (3%)
Query: 420 SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHAL-SDKPELRPFEPASTSV 478
SE+ L ++W+TVE+GL + K YGA LLSSIGE + SD P+L P+ + +
Sbjct: 208 SEMALLGRLHWWTVEYGLIGTLEDPKIYGAGLLSSIGESSSCMKSDVPKL-PYTIDAIN- 265
Query: 479 QPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
PY + QP +V ETF++ D ++ TM+
Sbjct: 266 HPYDITKTQPQLFVTETFQNLIDVLEQFADTMA 298
Score = 52.4 bits (120), Expect = 3e-05
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 7/135 (5%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT I+ W+ V + + A Y + LQ A + + + IP L+ ++ L K
Sbjct: 31 YTPIDQAVWRYVMRQNYSYLKQVAFYPY---IKGLQRAGLSIEY-IPDLQTMNDNLGK-I 85
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ G + F+ A+ V +R N +TP PD IHE GH P++AD
Sbjct: 86 GWGAVTVDGFIPPAAFMEYQAYHVLVIAADIRQINHIQYTPAPDIIHESAGHAPIIADAD 145
Query: 403 FAQFSQEIGLASLGA 417
+ + G S+GA
Sbjct: 146 YNSYLSYFG--SIGA 158
>UniRef50_A7HE07 Cluster: Aromatic amino acid hydroxylase; n=5;
Cystobacterineae|Rep: Aromatic amino acid hydroxylase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 59.3 bits (137), Expect = 3e-07
Identities = 37/143 (25%), Positives = 70/143 (48%), Gaps = 8/143 (5%)
Query: 282 AYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKH 341
AYT ++ W+ + + + A Y A L+A I V RIP+L++++ L +
Sbjct: 26 AYTPRDHAVWRHILRRLTAHLRSRAHPRYLAG---LEATGIDV-ERIPRLDEMNERLAR- 80
Query: 342 TGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADP 401
G+ G + F + RV +R + +TP PD +HE GH P +ADP
Sbjct: 81 AGWAAVAVRGFIPPAVFTELQSRRVLAIAADIRTHEHIEYTPAPDIVHESAGHAPFIADP 140
Query: 402 SFAQF---SQEIGLASLGASDSE 421
++A++ + E+G ++ +++ +
Sbjct: 141 TYAEYLRRAGEVGFRAIASAEDQ 163
Score = 57.2 bits (132), Expect = 1e-06
Identities = 36/117 (30%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 396 PLLADPSFAQFSQEIGLASLGAS-DSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSS 454
P + A Q + A+ SE + S +YW+T E+GL + YGA LLSS
Sbjct: 179 PTAGEEEVALAEQRLAAAAASVRYASESTRASRLYWWTAEYGLVGALDAPRLYGAGLLSS 238
Query: 455 IGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
IGE +H L+ E P A + Y QP +VA F+ + + +T+S
Sbjct: 239 IGEAVHCLTPAVEKLPLTAACADL-AYDITRMQPQLFVARDFDQLFEVLDGFAATLS 294
>UniRef50_A3U7E2 Cluster: Phenylalanine 4-monooxygenase; n=13;
Bacteroidetes|Rep: Phenylalanine 4-monooxygenase -
Croceibacter atlanticus HTCC2559
Length = 586
Score = 56.4 bits (130), Expect = 2e-06
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 5/129 (3%)
Query: 283 YTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFLRKHT 342
YT I W+ V ++ + K A Y + +K I + + IP + ++ L K
Sbjct: 30 YTAINQAVWRYVMRKNVEYLGKVAHESYLSGLKK---TGISI-NEIPSMYGMNRIL-KDI 84
Query: 343 GFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLLADPS 402
G+ G + F+ A++V +R + +TP PD IHE GH P++A P
Sbjct: 85 GWAAVAVDGFIPPNAFMEFQAYKVLVIASDIRQLENIEYTPAPDIIHEGAGHAPIIASPD 144
Query: 403 FAQFSQEIG 411
+A++ + G
Sbjct: 145 YAEYLRRFG 153
Score = 54.8 bits (126), Expect = 6e-06
Identities = 29/92 (31%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 420 SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRPFEPASTSVQ 479
SEI + ++W+TVE+GL + K YGA LLSSIGE + ++D + P+ + Q
Sbjct: 207 SEISLIRNLHWWTVEYGLVGTVEDPKIYGAGLLSSIGESKNCMTDAVKKIPYS-IDAAYQ 265
Query: 480 PYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
+ + QP +V F ++ + +TM+
Sbjct: 266 DFDITKQQPQLFVTPDFAYLQEVLEEFANTMA 297
>UniRef50_A4A633 Cluster: Putative uncharacterized protein; n=1;
Congregibacter litoralis KT71|Rep: Putative
uncharacterized protein - Congregibacter litoralis KT71
Length = 596
Score = 55.2 bits (127), Expect = 4e-06
Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 3/106 (2%)
Query: 409 EIGLASLGASD---SEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDK 465
E LA+LG SD SE L+ ++W+TVE+GL E + + +GA LLSS+GE L D+
Sbjct: 195 EARLAALGDSDGEPSEAALLTRLHWWTVEYGLVGELEDYRLFGAGLLSSLGESQSCLDDE 254
Query: 466 PELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMS 511
+ + PY QP +V ++ + +TM+
Sbjct: 255 RVKKLPLTVNAVETPYDITSTQPQLFVTKSCRHMSQVLEEFAATMA 300
Score = 52.4 bits (120), Expect = 3e-05
Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 7/163 (4%)
Query: 279 PSIAYTEIENGTWQRVFNTVLDLMPKHACREYKAAFEKLQAADIFVPHRIPQLEDVSSFL 338
P YT ++ W+ + + + + A Y E L I + H IP ++++++ L
Sbjct: 28 PDAQYTPRDHAVWRFLMTALTRGLAQTAHPVY---LEGLSRTGIALDH-IPSIDEMNACL 83
Query: 339 RKHTGFTLRPAAGLLTARDFLASLAFRVFQSTQYVRHNNSPFHTPEPDCIHELLGHIPLL 398
K G+ G + F+ A +V +R +TP PD +HE GH P L
Sbjct: 84 AK-LGWRAVVVDGFIPPAIFMEFQALKVLVIALDMRSVEHLLYTPAPDILHESAGHAPFL 142
Query: 399 ADPSFAQFSQEIGLASLGASDSEIEKLSTVYWFTVEFGLCKEN 441
D +A+F Q G + A + + +Y E + KEN
Sbjct: 143 VDVDYAEFLQRFGEVGMQAIANAHD--HELYEAIRELSILKEN 183
>UniRef50_Q55658 Cluster: Sll0023 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Sll0023 protein - Synechocystis sp.
(strain PCC 6803)
Length = 447
Score = 36.7 bits (81), Expect = 1.6
Identities = 23/75 (30%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 472 EPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSV 531
+P S +P Q Q Y A+ D K+ WV + +PF ++F+P E + S
Sbjct: 2 QPIKISRRPRWRQHIQDNAYQADVLSDPAQKY--WVEALPQPFAIQFSPQEETAIAIAS- 58
Query: 532 DKLETLIWQLNTEML 546
+KL WQ+ E L
Sbjct: 59 EKL----WQMCVEFL 69
>UniRef50_A2FAA9 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 387
Score = 36.3 bits (80), Expect = 2.2
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 459 LHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRF 518
L L KP+++ F SV+P Q Y A ++ D + MS F + F
Sbjct: 171 LRFLDYKPDMKRFNDVQPSVRPSQTMNGVKDYKTAPIVKNIHDNQHIFEKQMS--FALSF 228
Query: 519 NPHTERVEVLDSVDK 533
NPHTE +L+ +K
Sbjct: 229 NPHTEVSTILNKSNK 243
>UniRef50_A0DNH6 Cluster: Chromosome undetermined scaffold_58, whole
genome shotgun sequence; n=5; Alveolata|Rep: Chromosome
undetermined scaffold_58, whole genome shotgun sequence -
Paramecium tetraurelia
Length = 2383
Score = 36.3 bits (80), Expect = 2.2
Identities = 15/54 (27%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 451 LLSSIGELLHALSDKPELRPFEPASTSVQ-PYQDQEYQPIYYVAETFEDAKDKF 503
L +SI +L+ + P+++ EPA ++++ + Q Y+P +YV + +D+ ++F
Sbjct: 1497 LYNSIKQLMRPYTSTPQIQHREPAHSAIEFRHNVQHYKPKFYVTKAHQDSNEQF 1550
>UniRef50_A6SP41 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 112
Score = 35.9 bits (79), Expect = 2.8
Identities = 18/63 (28%), Positives = 36/63 (57%)
Query: 492 VAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLIWQLNTEMLHLTNA 551
V +TFE +K KF ++ S+ ++ + N ++VEV + V+ +E + Q T ++H+
Sbjct: 22 VVDTFESSKKKFLKFESSKNKILKKFKNKKAKKVEVFEVVEVVEQVEVQQPTRIIHVRME 81
Query: 552 VKK 554
+ K
Sbjct: 82 ITK 84
>UniRef50_Q4QCC9 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 3199
Score = 35.1 bits (77), Expect = 5.0
Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 3/146 (2%)
Query: 411 GLASLGASDSEIEKLSTVYWFTVEFGLCKENQQLKAYGAALLSSIGELLHALSDKPELRP 470
G+ + G+S S E S YW L K +QL++ A I L LS++ R
Sbjct: 1469 GVEAAGSSQSPQE--SAQYWKGQHTTLLKRFEQLQSEYDAFAQDIAALQRRLSEQEATRQ 1526
Query: 471 FEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDS 530
+ S ++ Q++ ++ E D + S + HTE L +
Sbjct: 1527 EQEQSRMMRDATSQQFTTLHQRLEEMSKVVDAAQADAQASSEKLQYLTARHTENEAALQA 1586
Query: 531 -VDKLETLIWQLNTEMLHLTNAVKKL 555
VD L + + E+ N ++L
Sbjct: 1587 EVDGLRSQLQSARDEVARANNLNEEL 1612
>UniRef50_A6WN31 Cluster: Putative uncharacterized protein; n=1;
Shewanella baltica OS185|Rep: Putative uncharacterized
protein - Shewanella baltica OS185
Length = 176
Score = 34.7 bits (76), Expect = 6.6
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 3/62 (4%)
Query: 149 MGSLARILKTIDNYKGCVQHLETRPSQVTGVQFDALVKVSMTRINLIQLIRSLRQSTAFA 208
+G L+++ KT++ + CV H E P T LV+ + I L +LI L++ T F
Sbjct: 98 LGDLSQLFKTLEGCQYCVTHSELNPGYST---IGVLVEQPDSPIELAELIEKLKKVTLFH 154
Query: 209 GV 210
+
Sbjct: 155 AI 156
>UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_00781040;
n=1; Tetrahymena thermophila SB210|Rep: hypothetical
protein TTHERM_00781040 - Tetrahymena thermophila SB210
Length = 2198
Score = 34.3 bits (75), Expect = 8.7
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 4/87 (4%)
Query: 466 PELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDKFRRWVSTMSRPFEVRFNPHTERV 525
P+++ +S + P++ Q + E +D ++ + + T+S+ N +E
Sbjct: 1796 PKIKSQNQSSKQI-PFESQVQSQQNQIIEELQDKLNELQLEIETLSQQM---LNYQSENQ 1851
Query: 526 EVLDSVDKLETLIWQLNTEMLHLTNAV 552
E+ D ++KL+++ ++ T+ L LTN V
Sbjct: 1852 ELNDQIEKLKSINEKMTTDNLDLTNQV 1878
>UniRef50_Q8F1U5 Cluster: Molybdate metabolism regulator; n=2;
Leptospira interrogans|Rep: Molybdate metabolism
regulator - Leptospira interrogans
Length = 276
Score = 34.3 bits (75), Expect = 8.7
Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 1/49 (2%)
Query: 454 SIGELLHALSDKPELRPFEPASTSVQPYQDQEYQPIYYVAETFEDAKDK 502
++ EL A+S PEL PF S P+ + E Q + V E FE AK++
Sbjct: 85 TVEELKTAVSQLPELAPFLE-KLSALPWDEYEKQLFHNVVEAFESAKEE 132
>UniRef50_A6GBQ3 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative uncharacterized
protein - Plesiocystis pacifica SIR-1
Length = 2507
Score = 34.3 bits (75), Expect = 8.7
Identities = 18/74 (24%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 224 WFPRHASDLDNCNHLMTKYEPELDMNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSIAY 283
W + LDN ++ +YEP H +Y + + + + + DPI +
Sbjct: 1374 WIGNGRAILDNKGQVLRQYEPYFSSTH------EYEDEAELVEQGVSPLMHYDPIGRVVR 1427
Query: 284 TEIENGTWQRVFNT 297
T++ NGT+ +V T
Sbjct: 1428 TDLPNGTFSKVETT 1441
>UniRef50_A3IP91 Cluster: Putative uncharacterized protein; n=3;
Cyanothece sp. CCY 0110|Rep: Putative uncharacterized
protein - Cyanothece sp. CCY 0110
Length = 97
Score = 34.3 bits (75), Expect = 8.7
Identities = 16/42 (38%), Positives = 24/42 (57%)
Query: 44 KQTKQSVLEEARARANDSGLESDFIQDGVHIGNGDNSPTVED 85
++T QS L+ R R ++G D QD + GNG+NS V +
Sbjct: 46 QRTTQSNLDSRRGRGENTGNAQDSYQDSLQEGNGNNSSQVSN 87
>UniRef50_O97291 Cluster: Putative uncharacterized protein MAL3P7.21;
n=4; Plasmodium|Rep: Putative uncharacterized protein
MAL3P7.21 - Plasmodium falciparum (isolate 3D7)
Length = 1946
Score = 34.3 bits (75), Expect = 8.7
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 237 HLMTKYEPELD--MNHPGFADKDYRERRKQIAEIAFAYKYGDPIPSIAYTEIEN 288
+L+TKYE ELD M FA Y++ ++I ++ K D + + EIEN
Sbjct: 1790 NLVTKYEKELDSYMTKYEFAHAKYKQYEEEIKDLKNKLKLKDEVIEYTHKEIEN 1843
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.133 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 575,723,719
Number of Sequences: 1657284
Number of extensions: 22994127
Number of successful extensions: 53537
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 53380
Number of HSP's gapped (non-prelim): 90
length of query: 561
length of database: 575,637,011
effective HSP length: 105
effective length of query: 456
effective length of database: 401,622,191
effective search space: 183139719096
effective search space used: 183139719096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 75 (34.3 bits)
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