BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000560-TA|BGIBMGA000560-PA|IPR000719|Protein kinase, IPR002290|Serine/threonine protein kinase, IPR011009|Protein kinase-like (593 letters) Database: spombe 5004 sequences; 2,362,478 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces... 171 2e-43 SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces po... 156 7e-39 SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosacch... 137 4e-33 SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosacc... 132 1e-31 SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomy... 121 3e-28 SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc... 119 1e-27 SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2... 114 3e-26 SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1||... 106 7e-24 SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccha... 105 2e-23 SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizo... 101 2e-22 SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase... 95 2e-20 SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|c... 93 1e-19 SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosa... 87 5e-18 SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccha... 86 1e-17 SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosacchar... 86 1e-17 SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizo... 85 3e-17 SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosac... 84 5e-17 SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharom... 83 1e-16 SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosa... 79 1e-15 SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizo... 79 2e-15 SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizo... 78 4e-15 SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase ki... 78 4e-15 SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gc... 77 9e-15 SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosacchar... 76 1e-14 SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |S... 76 2e-14 SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosa... 74 5e-14 SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |S... 73 9e-14 SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizos... 73 1e-13 SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |S... 73 1e-13 SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalyt... 71 5e-13 SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosa... 71 5e-13 SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces ... 70 8e-13 SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Pp... 70 8e-13 SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyc... 69 2e-12 SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosa... 69 2e-12 SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase P... 69 2e-12 SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Sch... 68 3e-12 SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosacch... 68 4e-12 SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosa... 67 6e-12 SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1... 67 6e-12 SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizos... 67 7e-12 SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosa... 66 2e-11 SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosac... 66 2e-11 SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|ch... 65 2e-11 SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating ... 65 2e-11 SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccha... 65 2e-11 SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schiz... 65 3e-11 SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyc... 65 3e-11 SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe... 64 4e-11 SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|... 63 1e-10 SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Sch... 62 3e-10 SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity prote... 61 5e-10 SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizos... 60 6e-10 SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Sch... 60 6e-10 SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schiz... 60 1e-09 SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Sch... 58 3e-09 SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizos... 58 5e-09 SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomy... 57 6e-09 SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Sc... 57 8e-09 SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schi... 57 8e-09 SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Sch... 56 1e-08 SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk... 56 1e-08 SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schiz... 56 2e-08 SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizos... 55 2e-08 SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosacc... 55 2e-08 SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizos... 54 6e-08 SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase S... 52 2e-07 SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosac... 52 3e-07 SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizos... 52 3e-07 SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizo... 52 3e-07 SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizos... 50 9e-07 SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase ... 50 9e-07 SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |... 48 4e-06 SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|S... 47 6e-06 SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomy... 47 8e-06 SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizo... 47 8e-06 SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizos... 47 8e-06 SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizo... 46 1e-05 SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schi... 46 1e-05 SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizo... 45 3e-05 SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosac... 45 3e-05 SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosac... 45 3e-05 SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosac... 44 6e-05 SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schi... 43 1e-04 SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schiz... 43 1e-04 SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein k... 42 3e-04 SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosacchar... 41 4e-04 SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizos... 40 7e-04 SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosa... 38 0.004 SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosa... 37 0.007 SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizos... 35 0.028 SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizo... 34 0.048 SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosa... 34 0.064 SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizos... 33 0.11 SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizos... 32 0.20 SPBC1703.05 |||protein kinase, RIO family|Schizosaccharomyces po... 31 0.45 SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizos... 31 0.45 SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosa... 31 0.45 SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosac... 29 2.4 SPAC926.04c |hsp90|swo1|heat shock protein Hsp90|Schizosaccharom... 27 5.6 SPBC11C11.07 |rpl1801|rpl18-1, rpl18|60S ribosomal protein L18|S... 27 5.6 SPAPB17E12.13 |rpl1802|rpl18-2|60S ribosomal protein L18|Schizos... 27 7.3 SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces po... 27 7.3 SPAC17A5.07c |ulp2||SUMO deconjugating cysteine peptidase Ulp2 |... 27 9.7 >SPAC2C4.14c |ppk11||PAK-related kinase Ppk11|Schizosaccharomyces pombe|chr 1|||Manual Length = 312 Score = 171 bits (416), Expect = 2e-43 Identities = 96/237 (40%), Positives = 138/237 (58%), Gaps = 22/237 (9%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85 GGS LD++K ++G F E IA V+++VL+ L Y H G++HRD+KA NIL + Sbjct: 86 GGSCLDLLK--------LSGTFSERVIAEVMRQVLEALVYLHGQGKMHRDIKAANILTMK 137 Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145 DG V+LADFGVS L + RD + FVGTP WMAPEV++Q GY++KADIWS GIT Sbjct: 138 DGLVKLADFGVSGQLESLRDKN-----DDFVGTPFWMAPEVVKQT-GYNYKADIWSLGIT 191 Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205 A E+ATG PY PMKVL+L ++ PP+L+ + + F + +CL+K+P Sbjct: 192 AYELATGEPPYSGIHPMKVLLLIPKHSPPSLER--------SKFSRAFCDFVSNCLKKNP 243 Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTM 262 R TA L KH F KK + + + + E+ + + +++T G T+ Sbjct: 244 KDRATAEYLSKHKFIKKYCPNTSVKEVVASYAKWKESELLPEATPYNSTMGNSANTI 300 >SPAC9G1.09 |sid1||PAK-related kinase Sid1|Schizosaccharomyces pombe|chr 1|||Manual Length = 471 Score = 156 bits (379), Expect = 7e-39 Identities = 91/191 (47%), Positives = 112/191 (58%), Gaps = 16/191 (8%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED-GTVQLADFGVSAWLATG 103 G +E I+ +L+EVL GL Y H +IHRD+KA NILL G V+LADFGV+A L+ Sbjct: 99 GRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANILLSSSTGNVKLADFGVAAQLSNA 158 Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163 SR RHTFVGTP WMAPEV++Q Y ADIWS GITAIEMA G P PM+ Sbjct: 159 A--SR---RHTFVGTPFWMAPEVIQQT-SYGLAADIWSLGITAIEMANGIPPRATMHPMR 212 Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223 V+ Q++PP LD + TFR + CL +P R +A ELL+HPF K A Sbjct: 213 VIFEIPQSEPPKLD---------DHFSPTFRDFVSCCLDLNPNMRWSAKELLQHPFIKSA 263 Query: 224 KDRKYLTQTLV 234 K + LV Sbjct: 264 GTVKDIIPLLV 274 >SPBC17F3.02 |nak1|orb3, mor4|PAK-related kinase Nak1|Schizosaccharomyces pombe|chr 2|||Manual Length = 652 Score = 137 bits (332), Expect = 4e-33 Identities = 74/178 (41%), Positives = 104/178 (58%), Gaps = 14/178 (7%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G E I+ +L+E L+ L++ H G IHRD+KA NIL+ G V+L DFGV+A L Sbjct: 103 GPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGVAAEL---- 158 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164 +++R+K R TF+GTP WMAPEV+ Y+ ADIWS GITA E+ATG+ P+ K P + Sbjct: 159 NINRRK-RITFIGTPYWMAPEVIRDGQEYNVMADIWSLGITAYEIATGSPPHAKEDPFRA 217 Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222 + L PP L+ + ++ I CLQ P +R ++ELLK F K+ Sbjct: 218 VYLIAHTAPPRLNGN---------FSALLKEFIASCLQDVPQRRLDSSELLKSKFIKQ 266 >SPBC1604.14c |shk1|pak1, orb2|PAK-related kinase Shk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 658 Score = 132 bits (320), Expect = 1e-31 Identities = 77/198 (38%), Positives = 105/198 (53%), Gaps = 22/198 (11%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85 GGSL +V+ N E IA + KE L+GL++ H NG +HRD+K+ NILL Sbjct: 465 GGSLTEVV---------TNNTLSEGQIAAICKETLEGLQHLHENGIVHRDIKSDNILLSL 515 Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145 G ++L DFG A + D + K R T VGTP WMAPEV+ + Y FK D+WS GI Sbjct: 516 QGDIKLTDFGFCAQI----DSNMTK-RTTMVGTPYWMAPEVVTRKE-YGFKVDVWSLGIM 569 Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205 AIEM G PY P++ L L P + + + F + L +P Sbjct: 570 AIEMVEGEPPYLNENPLRALYLIATIGTPKI-------SRPELLSSVFHDFLSKSLTVNP 622 Query: 206 TKRPTATELLKHPFFKKA 223 +RP++ ELL+HPF K+A Sbjct: 623 KQRPSSGELLRHPFLKQA 640 >SPAC1F5.09c |shk2|pak2|PAK-related kinase Shk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 589 Score = 121 bits (291), Expect = 3e-28 Identities = 68/175 (38%), Positives = 92/175 (52%), Gaps = 13/175 (7%) Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108 EA IA + E KG+++ H+ IHRD+K+ N+LL G +++ DFG A L+ +R Sbjct: 408 EAQIARICLETCKGIQHLHARNIIHRDIKSDNVLLDNSGNIKITDFGFCARLS-----NR 462 Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLT 168 R T VGTP WMAPEV++Q+ Y K DIWS GI IEM PY + P++ L L Sbjct: 463 TNKRVTMVGTPYWMAPEVVKQNE-YGTKVDIWSLGIMIIEMIENEPPYLREDPIRALYLI 521 Query: 169 LQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223 +N P L + K + + CL D R TA ELL H F +A Sbjct: 522 AKNGTPTL-------KKPNLVSKNLKSFLNSCLTIDTIFRATAAELLTHSFLNQA 569 >SPBC21.06c |cdc7|pld1, its10|serine/threonine protein kinase Cdc7|Schizosaccharomyces pombe|chr 2|||Manual Length = 1062 Score = 119 bits (286), Expect = 1e-27 Identities = 71/181 (39%), Positives = 98/181 (54%), Gaps = 18/181 (9%) Query: 40 SNCVN-GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA 98 S C N G E +A +VL+GL Y H+ G IHRD+K NIL +DGT++LADFGV+ Sbjct: 95 SICKNFGKIPENLVALYTFQVLQGLLYLHNQGVIHRDIKGANILTTKDGTIKLADFGVAT 154 Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHK 158 + D H+ VG+P WMAPEV+E G +DIWS G T IE+ G PY+ Sbjct: 155 KINALED-------HSVVGSPYWMAPEVIEL-VGATTASDIWSVGCTVIELLDGNPPYYD 206 Query: 159 YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218 P L ++++ P L + + K+F ++ C QKDP R +LLKHP Sbjct: 207 LDPTSALFRMVKDEHPPLPS------NISSAAKSF---LMQCFQKDPNLRIKTRKLLKHP 257 Query: 219 F 219 + Sbjct: 258 W 258 >SPBC1D7.05 |byr2|ste8, SPBC2F12.01|MAP kinase kinase kinase Byr2|Schizosaccharomyces pombe|chr 2|||Manual Length = 659 Score = 114 bits (275), Expect = 3e-26 Identities = 66/176 (37%), Positives = 91/176 (51%), Gaps = 11/176 (6%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G F+E + +K+ LKGLEY HS G +HRD+K NIL+ G ++++DFG+S L Sbjct: 492 GSFEETLVKNFIKQTLKGLEYLHSRGIVHRDIKGANILVDNKGKIKISDFGISKKLELNS 551 Query: 105 DMSRQ-KVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163 ++ R +F G+ WMAPEV++Q + K DIWS G IEM T PY M+ Sbjct: 552 TSTKTGGARPSFQGSSFWMAPEVVKQTM-HTEKTDIWSLGCLVIEMLTSKHPYPNCDQMQ 610 Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219 + +N P + KTF +DC RPTA+ELL HPF Sbjct: 611 AIFRIGENILPEFPSNI-SSSAIDFLEKTF---AIDC-----NLRPTASELLSHPF 657 >SPAC1F3.02c |mkh1||MEK kinase |Schizosaccharomyces pombe|chr 1|||Manual Length = 1116 Score = 106 bits (255), Expect = 7e-24 Identities = 62/179 (34%), Positives = 90/179 (50%), Gaps = 10/179 (5%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G F+E + V ++VL GL Y HS G IHRD+KA N+L+ DG +++DFG+S Sbjct: 925 GPFEEQLVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVY 984 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDH-GYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163 D + G+ WMAPEV+ DH GY K D+WS G +EM G P+ ++ Sbjct: 985 D---NDANLSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQ 1041 Query: 164 VLM-LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221 + L + P + + + +A + + C + RPTA ELL HPF K Sbjct: 1042 AMFKLGTEKKAPPIPSELVSQVSPEAI-----QFLNACFTVNADVRPTAEELLNHPFMK 1095 >SPBC543.07 |pek1|skh1, mkk1|MAP kinase kinase Pek1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 363 Score = 105 bits (252), Expect = 2e-23 Identities = 74/215 (34%), Positives = 105/215 (48%), Gaps = 20/215 (9%) Query: 12 WSNTEDDYEIG-DVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNG 70 ++N E I + G LD I ++R G E + + VL GL Y H Sbjct: 145 YNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTG---ERPLGKIAFGVLSGLSYLHDRK 201 Query: 71 QIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD 130 IHRD+K NILL G V+L DFGVS L + TF GT +MAPE + Sbjct: 202 IIHRDIKPSNILLTSKGQVKLCDFGVSGELV-------NSLAGTFTGTSYYMAPERI-SG 253 Query: 131 HGYDFKADIWSFGITAIEMATGTAPY---HKYPPMKVLMLT-LQNDPPNLDTGAEEKDQY 186 Y +DIWS G+T +E+A P+ PPM + +L+ + N PP L ++ Sbjct: 254 GSYTISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPL---LPQEPGI 310 Query: 187 KAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221 K + K+F+ + CL KD T+RP ++L HP+ K Sbjct: 311 K-WSKSFQHFLCVCLDKDKTRRPGPQKMLTHPWVK 344 >SPAC9G1.02 |wis4|wak1, wik1|MAP kinase kinase kinase Wis4|Schizosaccharomyces pombe|chr 1|||Manual Length = 1401 Score = 101 bits (243), Expect = 2e-22 Identities = 71/247 (28%), Positives = 119/247 (48%), Gaps = 31/247 (12%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85 GGSL D++ H + DE + + ++L+GL Y HS +HRD+K NILL Sbjct: 1120 GGSLADLLAH--------GRIEDENVLKVYVVQLLEGLAYIHSQHILHRDIKPANILLDH 1171 Query: 86 DGTVQLADFGVSAWLATGRDMS------RQKVRHTFVGTPCWMAPEVMEQDHGYDFKA-D 138 G ++ +DFG + +++ D + +++H GTP +MAPE++ DF A D Sbjct: 1172 RGMIKYSDFGSALYVSPPTDPEVRYEDIQPELQH-LAGTPMYMAPEIILGTKKGDFGAMD 1230 Query: 139 IWSFGITAIEMATGTAPYHKYPPMKVLML-TLQNDPPNLDTGAEEKDQYKAYGKTFRKMI 197 IWS G +EM TG+ P+ + +M P++ Q + R I Sbjct: 1231 IWSLGCVILEMMTGSTPWSEMDNEWAIMYHVAAMHTPSI-------PQNEKISSLARDFI 1283 Query: 198 VDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257 C ++DP +RP A +LL HP+ + +T++ + P+ T+ K S H+ T + Sbjct: 1284 EQCFERDPEQRPRAVDLLTHPWI-----TDFRKKTIITMPPATITK--KTSLSHTITEEK 1336 Query: 258 LHRTMTG 264 + + G Sbjct: 1337 TAQLLAG 1343 >SPACUNK12.02c |cmk1||calcium/calmodulin-dependent protein kinase Cmk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 335 Score = 95.5 bits (227), Expect = 2e-20 Identities = 57/186 (30%), Positives = 94/186 (50%), Gaps = 14/186 (7%) Query: 42 CVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILL---GEDGTVQLADFGVSA 98 C G F EA A +++ ++Y H NG +HRD+K N+L + + +ADFG+S Sbjct: 121 CAKGSFYEADAAALMRTTTSAVKYLHDNGIVHRDLKPENLLYRSKDPNSDLLIADFGLSH 180 Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHK 158 + + S+ + T GTP +MAPEV + GY D+W+ G+ + +G P+ + Sbjct: 181 FY----EDSQYYMLMTACGTPEYMAPEVFRRT-GYGKPVDMWAIGVITYFLLSGYTPFAR 235 Query: 159 YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218 ++V+ L N+ D + +T + I CL+ DP+KR TA + LKHP Sbjct: 236 PSQVEVIEAILANEYTFND------PCWSGISETAKDFIKKCLENDPSKRLTAADALKHP 289 Query: 219 FFKKAK 224 F + + Sbjct: 290 FLSEKR 295 >SPAC23C11.16 |plo1||Polo kinase Plo1|Schizosaccharomyces pombe|chr 1|||Manual Length = 683 Score = 92.7 bits (220), Expect = 1e-19 Identities = 54/176 (30%), Positives = 87/176 (49%), Gaps = 20/176 (11%) Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108 E + ++ ++L L+Y H IHRD+K GNI+L E V++ DFG++A L M Sbjct: 137 EPEVRYLMMQILGALKYMHKKRVIHRDLKLGNIMLDESNNVKIGDFGLAALL-----MDD 191 Query: 109 QKVRHTFVGTPCWMAPEVM-EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLML 167 ++ + T GTP ++APE++ G+ F+ D+WS G+ + G P+ + Sbjct: 192 EERKMTICGTPNYIAPEILFNSKEGHSFEVDLWSAGVVMYALLIGKPPFQDKEVKTIYRK 251 Query: 168 TLQND---PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF 220 N P N+D AE KD +I L DP+ RP+ +++ H FF Sbjct: 252 IKANSYSFPSNVDISAEAKD-----------LISSLLTHDPSIRPSIDDIVDHEFF 296 >SPAC1B9.02c |sck1||serine/threonine protein kinase Sck1|Schizosaccharomyces pombe|chr 1|||Manual Length = 696 Score = 87.4 bits (207), Expect = 5e-18 Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 18/180 (10%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G F E + E++ LE+ H + I+RD+K NILL DG + L DFG+S Sbjct: 398 GRFPEQRAKFYIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSK-----A 452 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164 ++S +TF GT ++APEV+ +D GY + D WS G+ EM G +P++ P ++ Sbjct: 453 NLSANATTNTFCGTTEYLAPEVLLEDKGYTKQVDFWSLGVLVFEMCCGWSPFYA-PDVQQ 511 Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTA----TELLKHPFF 220 + + G + G++F + L ++P R A TEL +HPFF Sbjct: 512 MYRNIAFGKVRFPKGVLSSE-----GRSF---VRGLLNRNPNHRLGAVADTTELKEHPFF 563 >SPBC409.07c |wis1|spc2, smf2|MAP kinase kinase Wis1|Schizosaccharomyces pombe|chr 2|||Manual Length = 605 Score = 86.2 bits (204), Expect = 1e-17 Identities = 64/188 (34%), Positives = 90/188 (47%), Gaps = 26/188 (13%) Query: 45 GVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103 G+ DE +A V++GL+ + IHRDVK N+L+ +G V+L DFGVS L Sbjct: 410 GIKDEGVLARTAYAVVQGLKTLKEEHNIIHRDVKPTNVLVNSNGQVKLCDFGVSGNLVA- 468 Query: 104 RDMSRQKVRHTFVGTPCWMAPE---VMEQDHG---YDFKADIWSFGITAIEMATGTAPY- 156 + T +G +MAPE V +G Y +AD+WS G+T +EMA G PY Sbjct: 469 ------SISKTNIGCQSYMAPERIRVGGPTNGVLTYTVQADVWSLGLTILEMALGAYPYP 522 Query: 157 -HKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATEL 214 Y + L DPP+L D + + F + CL K+P+ RP EL Sbjct: 523 PESYTSIFAQLSAICDGDPPSL------PDSFSPEARDF---VNKCLNKNPSLRPDYHEL 573 Query: 215 LKHPFFKK 222 HP+ K Sbjct: 574 ANHPWLLK 581 >SPAC1D4.13 |byr1|ste1, ste3|MAP kinase kinase Byr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 340 Score = 86.2 bits (204), Expect = 1e-17 Identities = 57/179 (31%), Positives = 92/179 (51%), Gaps = 24/179 (13%) Query: 52 IATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQK 110 + ++ ++KGL Y ++ I HRD+K N+++ G ++L DFGVS L Sbjct: 162 LGKIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELV-------NS 214 Query: 111 VRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY------HKYPPMKV 164 V TFVGT +M+PE + + Y K+DIWS GI+ IE+AT P+ + + Sbjct: 215 VAQTFVGTSTYMSPERI-RGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDL 273 Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223 L +Q +PP L + ++ + R + CL KDPT R + +L P+F++A Sbjct: 274 LHCIVQEEPPRLPS---------SFPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQA 323 >SPCC162.10 |ppk33||serine/threonine protein kinase Ppk33 |Schizosaccharomyces pombe|chr 3|||Manual Length = 338 Score = 85.0 bits (201), Expect = 3e-17 Identities = 58/181 (32%), Positives = 89/181 (49%), Gaps = 8/181 (4%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F+E+ I + E++ L Y HS G +HRDVK NILL E G +LADF V+A + T Sbjct: 123 FNESVIRIWMVELVSALIYIHSKGVLHRDVKPDNILLDEKGHCKLADFNVAAKVHTSSSP 182 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 S+ + VGTP +MAPE + Y ++D WS GIT E P+ + + + Sbjct: 183 SKSNMTVGRVGTPVYMAPETLIHAVSYK-ESDWWSLGITFYECLFQVRPFPNHLLINWIR 241 Query: 167 LTLQNDPPNLDTGAE----EKD-QYKAYGKTFRKMIVDCLQKDPTKR--PTATELLKHPF 219 + + + D + +D + K R ++ L+ D KR ++ +L HPF Sbjct: 242 ASEEEKASSADRLSSALHISRDKKLTTISKDARSAVMAFLEMDIKKRLGHSSKKLQTHPF 301 Query: 220 F 220 F Sbjct: 302 F 302 >SPCC18B5.11c |cds1||replication checkpoint kinase Cds1|Schizosaccharomyces pombe|chr 3|||Manual Length = 460 Score = 84.2 bits (199), Expect = 5e-17 Identities = 59/193 (30%), Positives = 95/193 (49%), Gaps = 18/193 (9%) Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWL-AT 102 NG DE +LK++L+ L + H G HRD+K NIL+ D ++++DFG++ + T Sbjct: 263 NGSIDEQDCKPLLKQLLETLLHLHKQGVTHRDIKPENILITNDFHLKISDFGLAKVIHGT 322 Query: 103 GRDMSRQKVRHTFVGTPCWMAPEVMEQ-----DHGYDFKADIWSFGITAIEMATGTAPYH 157 G + TF GT ++APEV++ D GYD K DIWS G M T + P+ Sbjct: 323 GTFL------ETFCGTMGYLAPEVLKSKNVNLDGGYDDKVDIWSLGCVLYVMLTASIPFA 376 Query: 158 KYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217 K + L + P ++ E + + +I L+ +P KR + +E L+H Sbjct: 377 SSSQAKCIELISKGAYP-IEPLLENEISEEGI-----DLINRMLEINPEKRISESEALQH 430 Query: 218 PFFKKAKDRKYLT 230 P+F ++ T Sbjct: 431 PWFYTVSTHEHRT 443 >SPBC12D12.04c |pck2|sts6, pkc1|protein kinase C |Schizosaccharomyces pombe|chr 2|||Manual Length = 1016 Score = 83.0 bits (196), Expect = 1e-16 Identities = 61/191 (31%), Positives = 91/191 (47%), Gaps = 22/191 (11%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVG 117 EV L+YFH NG I+RD+K NILL DG V++AD+G+ DM TF G Sbjct: 791 EVCLALKYFHDNGIIYRDLKLDNILLSPDGHVKVADYGLCK-----EDMWHDNTTATFCG 845 Query: 118 TPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLD 177 TP +MAPE++ + Y D W+FG+ +M G +P+ ++ L ++P L Sbjct: 846 TPEFMAPEILLEQQ-YTRSVDWWAFGVLIYQMLLGQSPFRGEDEEEIFDAILSDEP--LY 902 Query: 178 TGAEEKDQYKAYGKTFRKMIVDCLQKDPTKR----PT-ATELLKHPFFKKAK-DRKYLTQ 231 +D ++ L +DP KR P A +++ HPFF D Y + Sbjct: 903 PIHMPRDSV--------SILQQLLTRDPKKRLGSGPNDAEDVMTHPFFSNINWDDIYHKR 954 Query: 232 TLVAIGPSMET 242 T PS+ + Sbjct: 955 TQPPYIPSLNS 965 >SPCC297.03 |ssp1||serine/threonine protein kinase Ssp1 |Schizosaccharomyces pombe|chr 3|||Manual Length = 652 Score = 79.4 bits (187), Expect = 1e-15 Identities = 71/236 (30%), Positives = 103/236 (43%), Gaps = 28/236 (11%) Query: 40 SNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAW 99 ++C + V + ++V+ GLEY H G IHRD+K N+LL V+++DFGVS Sbjct: 232 TDCDSPVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYI 291 Query: 100 LATGRDMSRQKVRHTFVGTPCWMAPEVMEQD-----HGYDFKADIWSFGITAIEMATGTA 154 G + VGTP + APE+ D D+W+ G+T + G Sbjct: 292 ANAGLNEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKISEAIDVWALGVTLFCLLFGRC 351 Query: 155 PYH---KYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTA 211 P++ +Y ++ N P D G E +D K L KDP +R T Sbjct: 352 PFNASMEYELFDKIVNERLNIPSTPDIGEEGRDLLKR-----------LLCKDPEQRITL 400 Query: 212 TELLKHPF-FKKAKD-RKYLTQTLVAIGPSMETRV-TKASKKHSATS--GRLHRTM 262 E+ HP+ KD K+L T PS +RV + SA S GRL R + Sbjct: 401 VEVKLHPWTLDGLKDPEKWLQNT----DPSTVSRVEVSTDEVASAISLVGRLRRKL 452 >SPCC24B10.07 |gad8||serine/threonine protein kinase Gad8 |Schizosaccharomyces pombe|chr 3|||Manual Length = 569 Score = 79.0 bits (186), Expect = 2e-15 Identities = 63/215 (29%), Positives = 97/215 (45%), Gaps = 20/215 (9%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G FD + E+L LE H I+RD+K NILL G + L DFG+ Sbjct: 323 GCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCK-----L 377 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164 +M++ +TF GTP ++APE++ HGY D W+ G+ EM TG P++ ++ Sbjct: 378 NMAKTDRTNTFCGTPEYLAPELL-LGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEM 436 Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKR---PTATELLKHPFFK 221 LQ DP +EK + ++ L + P KR A E+ HPFF Sbjct: 437 YRKILQ-DPLRFPDNIDEK---------AKDLLSGLLTRAPEKRLGSGGAQEIKNHPFFD 486 Query: 222 KAKDRKYLTQTL-VAIGPSMETRVTKASKKHSATS 255 +K + + PS+E+ + ++ TS Sbjct: 487 DIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTS 521 >SPAC22E12.14c |sck2||serine/threonine protein kinase Sck2|Schizosaccharomyces pombe|chr 1|||Manual Length = 646 Score = 77.8 bits (183), Expect = 4e-15 Identities = 40/111 (36%), Positives = 58/111 (52%), Gaps = 5/111 (4%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F E + E+L L+ H G ++RD+K NILL G + L DFG+S ++ Sbjct: 364 FPEERAKFYIAELLLALQALHKRGIVYRDLKPENILLDVQGHIALCDFGLSK-----ANL 418 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYH 157 S TF GT ++APEV+ + GYD D WS G+ EM G +P++ Sbjct: 419 SVGTTTRTFCGTTDYLAPEVILDEAGYDMMVDFWSLGVLLYEMTCGWSPFY 469 >SPAC1006.09 |win1|SPAC1250.06c, SPAPJ730.01|MAP kinase kinase kinase Win1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1436 Score = 77.8 bits (183), Expect = 4e-15 Identities = 63/196 (32%), Positives = 93/196 (47%), Gaps = 31/196 (15%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGV-----SAWLAT 102 DE I + ++L+GL Y HS G H+DVK NIL +G ++ DFG SA Sbjct: 1217 DELVIQVYVLQLLEGLAYIHSCGVSHQDVKPENILFDHNGIMKFTDFGSAKMSGSASTKI 1276 Query: 103 GRDMSRQK----------VRH-------TFVGTPCWMAPEVMEQDHGYDFKA-DIWSFGI 144 +++Q+ ++H + GTP +MAPE++ + A DIWS G Sbjct: 1277 FEQLTQQEEEEFEKDSEFLQHLDQNRGYSLTGTPTYMAPELILGNPSERVGAMDIWSLGC 1336 Query: 145 TAIEMATGTAPYHKYPPMKVLMLTL-QNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQK 203 +EMATG+ P+ + LM + ++PP + DQ G+ F K C Sbjct: 1337 VIVEMATGSPPWPRLDNHFSLMYHIAAHNPPIIPA----DDQLSPLGQNFLKR---CFVS 1389 Query: 204 DPTKRPTATELLKHPF 219 DP +R TA ELL P+ Sbjct: 1390 DPNQRATAAELLMDPW 1405 >SPBC36B7.09 |gcn2|ppk28, ppk28, SPBP18G5.01|eIF2 alpha kinase Gcn2 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1576 Score = 76.6 bits (180), Expect = 9e-15 Identities = 64/199 (32%), Positives = 99/199 (49%), Gaps = 28/199 (14%) Query: 28 SLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDG 87 SL D+I+ KI V DE + + +++L+ L Y HS G +HRD+K GNI L E+ Sbjct: 735 SLQDIIRDKIPV--------DE--MWRLFRQILEALAYIHSRGMMHRDLKPGNIFLDENR 784 Query: 88 TVQLADFGVSAWLATGRD-----MSRQKVRH---TFVGTPCWMAPEVMEQDHG--YDFKA 137 V+L DFG++ +D +RQ T VGT ++APE++ + +G YD K Sbjct: 785 NVKLGDFGLATENENYQDNNDKWKNRQSADEDLTTGVGTALYVAPELLSRRNGVRYDAKV 844 Query: 138 DIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMI 197 D++S GI EM + + ++ ++ P + F K+I Sbjct: 845 DMYSLGIILFEMCMTFSTSME----RIRIIDTIRSP---SISFPSTFPFSRASHEF-KVI 896 Query: 198 VDCLQKDPTKRPTATELLK 216 LQ DPTKRP++ ELL+ Sbjct: 897 HCLLQHDPTKRPSSQELLE 915 Score = 45.2 bits (102), Expect = 3e-05 Identities = 42/175 (24%), Positives = 70/175 (40%), Gaps = 23/175 (13%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGT---VQLADFGVSAWLA--- 101 D T+ +L+GL H G H+ + N++L G +L DFG + L Sbjct: 347 DVETVRAFSNNILEGLAELHRLGISHKSLHLDNVVLFHSGHRTFAKLMDFGFTRTLRDMN 406 Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGY-DFKADIWSFGITAIEMATGTAPYHKYP 160 + T + PEV E K DIW FG+ ++M G +K+ Sbjct: 407 ASHPFNINSQSITNILPEGLYPPEVSESSFAAASRKTDIWCFGLLVLQMLCGAHVLNKFS 466 Query: 161 PMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215 +K++M + P +++ ++ CL +D KRP+A +LL Sbjct: 467 SLKLIMTHVIPLLPG----------------SYQDLVRRCLMRDSRKRPSAIDLL 505 >SPAC17G8.14c |pck1|SPAC22H10.01c|protein kinase C |Schizosaccharomyces pombe|chr 1|||Manual Length = 988 Score = 76.2 bits (179), Expect = 1e-14 Identities = 42/117 (35%), Positives = 64/117 (54%), Gaps = 8/117 (6%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVG 117 EV L+YFH NG +RD+K NILL DG +++AD+G+ +M TF G Sbjct: 772 EVCLALKYFHENGIAYRDLKLDNILLCPDGHIRIADYGLCK-----ENMLLGNTTSTFCG 826 Query: 118 TPCWMAPEV-MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDP 173 TP +MAPE+ +EQ + D D W+FG+ +M G +P+ ++ L ++P Sbjct: 827 TPEFMAPEILLEQQYSKD--VDWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEP 881 >SPAC890.03 |ppk16|mug92|serine/threonine protein kinase Ppk16 |Schizosaccharomyces pombe|chr 1|||Manual Length = 672 Score = 75.8 bits (178), Expect = 2e-14 Identities = 53/177 (29%), Positives = 85/177 (48%), Gaps = 18/177 (10%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMS 107 DE T ++ ++ ++Y H G +HRD+K NI L + V+L DFG S D S Sbjct: 121 DEKTTCRIMWQLCCAIQYLHRQGCVHRDLKLENIFLDKAYNVKLGDFGFS----RDSDCS 176 Query: 108 RQKVRHTFVGTPCWMAPEVMEQDHGYDFK-ADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 R+ +T GT + APE++ Q H Y + DIWS GI + G P+ + + + Sbjct: 177 RRTFMNTRCGTVAYCAPELV-QGHKYIGECVDIWSLGIIMYALLIGRLPFDE-DDVSLTE 234 Query: 167 LTLQNDPPNLDTGAEEKDQY-KAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222 + N+ P QY + K ++ L KD RP+ +++ HP+FK+ Sbjct: 235 QKIINECP----------QYPETLSKNSSSLLKSLLCKDYRLRPSIDQIISHPYFKE 281 >SPCC320.13c |ark1|aim1, SPCC330.16|aurora-B kinase Ark1|Schizosaccharomyces pombe|chr 3|||Manual Length = 355 Score = 74.1 bits (174), Expect = 5e-14 Identities = 50/179 (27%), Positives = 78/179 (43%), Gaps = 17/179 (9%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F E + + ++ L Y H IHRD+K NILLG DG ++L+DFG S + R Sbjct: 184 FSEEVASKYIFQMANALSYLHKKHVIHRDIKPENILLGIDGEIKLSDFGWSVHAPSNR-- 241 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 R T GT ++ PE++E + K D+WS G+ E G P+ Sbjct: 242 -----RTTLCGTLDYLPPEMVEGKE-HTEKVDLWSLGVLTYEFLVGAPPFEDMSGHSATY 295 Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225 + + + R +I LQ +P KR + ++++HP+ K KD Sbjct: 296 KRIAKVDLKIPSFVP---------PDARDLISRLLQHNPEKRMSLEQVMRHPWIVKYKD 345 >SPAC14C4.03 |mek1||Cds1/Rad53/Chk2 family protein kinase Mek1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 445 Score = 73.3 bits (172), Expect = 9e-14 Identities = 55/196 (28%), Positives = 90/196 (45%), Gaps = 33/196 (16%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDG----TVQLADFGVSAWL 100 G E T ++ ++L+GL+Y H IHRD+K NIL+ + L DFGV+ + Sbjct: 251 GTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKLENILIASSSDTIFRIILTDFGVARCM 310 Query: 101 ATGRDMSRQKVRHTFVGTPCWMAPEVM----------EQDHGYDFKADIWSFGITAIEMA 150 G+ +S TFVGTP + APE+ E GY + D+WS G+ + Sbjct: 311 QKGKRLS------TFVGTPEYTAPEIQRLKGRSQVEKENSSGYGKEVDLWSLGVIMFLLL 364 Query: 151 TGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPT 210 +G +P +K + + DP +K+ + + +I + L+ +P R T Sbjct: 365 SGNSPSFA-DGVKEKQVDFR-DP-----------VWKSVSRQAKDLISNLLKTNPPDRFT 411 Query: 211 ATELLKHPFFKKAKDR 226 + L HP+F + R Sbjct: 412 VKQCLSHPWFARHSSR 427 >SPAC23H4.02 |ppk9||serine/threonine protein kinase Ppk9 |Schizosaccharomyces pombe|chr 1|||Manual Length = 532 Score = 72.5 bits (170), Expect = 1e-13 Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 16/173 (9%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMS 107 DE T + ++++ ++Y H + HRD+K NILL +D V+L DFG+S ++ G +S Sbjct: 118 DECTTRKIFRQIVHAIDYCHLHRVAHRDLKLENILLNKDLVVKLTDFGLSNFMLDGSFLS 177 Query: 108 RQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLML 167 T GTP + APEV++ + D+W GI M G P+ + Sbjct: 178 ------TSCGTPHYAAPEVIQGRYYDGCDVDVWGCGILLYLMLVGEFPFED--------V 223 Query: 168 TLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF 220 T+ N + G + + +I L PT R E+++HP+F Sbjct: 224 TISNVLSRVCKGIYTIPSF--VSSSASDLIRQMLMVLPTSRIKVAEIMQHPWF 274 >SPBC4F6.06 |kin1||microtubule affinity-regulating kinase Kin1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 891 Score = 72.5 bits (170), Expect = 1e-13 Identities = 56/196 (28%), Positives = 86/196 (43%), Gaps = 24/196 (12%) Query: 24 VIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILL 83 V GG +LD I +S+ G E ++++ L Y H N +HRD+K NIL+ Sbjct: 223 VDGGQMLDYI-----ISH---GKLKEKQARKFVRQIGSALSYLHQNSVVHRDLKIENILI 274 Query: 84 GEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFG 143 + G +++ DFG+S RQ TF G+ + APE++ + D+WSFG Sbjct: 275 SKTGDIKIIDFGLS------NLYRRQSRLRTFCGSLYFAAPELLNAQPYIGPEVDVWSFG 328 Query: 144 ITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQK 203 I + G P+ M L ++ G E Y + ++ L Sbjct: 329 IVLYVLVCGKVPFDD-QNMSALHAKIKK-------GTVEYPSY--LSSDCKGLLSRMLVT 378 Query: 204 DPTKRPTATELLKHPF 219 DP KR T E+L HP+ Sbjct: 379 DPLKRATLEEVLNHPW 394 >SPBC106.10 |pka1|tpk, git6|cAMP-dependent protein kinase catalytic subunit Pka1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 512 Score = 70.9 bits (166), Expect = 5e-13 Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 25/193 (12%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F E EV+ L+Y H N ++RD+K N+LL G +++ DFG + ++T Sbjct: 296 FPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDRFGHLKIVDFGFAKRVSTSNCC 355 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 T GTP ++APE++ Y+ AD WS GI EM G P++ PMK+ Sbjct: 356 -------TLCGTPDYLAPEIISL-KPYNKAADWWSLGILIFEMLAGYPPFYSENPMKLYE 407 Query: 167 LTLQNDPPNLDTGAEEKDQYKAY-GKTFRKMIVDCLQKDPTKR-----PTATELLKHPFF 220 L E K Y +Y ++ LQ+D T R + +++ HP+F Sbjct: 408 NIL-----------EGKVNYPSYFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHPWF 456 Query: 221 KKAKDRKYLTQTL 233 + K LT+ + Sbjct: 457 RDISWDKILTRKI 469 >SPCC576.15c |ksg1||serine/threonine protein kinase Ksg1|Schizosaccharomyces pombe|chr 3|||Manual Length = 592 Score = 70.9 bits (166), Expect = 5e-13 Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 26/192 (13%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G F+E ++ ++Y H G IHRD+K NILL ++ ++ DFG + L + Sbjct: 193 GRFNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSH 252 Query: 105 DMSRQKVRH---------TFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155 + H +FVGT +++PEV+ D +DIW+FG +M G P Sbjct: 253 GSHEEDTHHADKPQAHSRSFVGTARYVSPEVL-SDKIAGTASDIWAFGCILFQMLAGKPP 311 Query: 156 Y---HKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTAT 212 + ++Y + ++ PP++ A + +K++V DP R T Sbjct: 312 FVAGNEYLTFQSILHLSYEIPPDISDVASD---------LIKKLLV----LDPKDRLTVD 358 Query: 213 ELLKHPFFKKAK 224 E+ +HPFF K Sbjct: 359 EIHQHPFFNGIK 370 >SPCC1259.13 |chk1|rad27|Chk1 protein kinase|Schizosaccharomyces pombe|chr 3|||Manual Length = 496 Score = 70.1 bits (164), Expect = 8e-13 Identities = 50/196 (25%), Positives = 92/196 (46%), Gaps = 22/196 (11%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85 GG L D I+ + + DE ++++G+ + HS G HRD+K NILL Sbjct: 96 GGDLFDKIEPDVGI--------DEDVAQFYFAQLMEGISFMHSKGVAHRDLKPENILLDY 147 Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145 +G ++++DFG ++ + + ++ ++ VG+P + APE+ +Q G K D+WS GI Sbjct: 148 NGNLKISDFGFASLFSY---KGKSRLLNSPVGSPPYAAPEITQQYDG--SKVDVWSCGII 202 Query: 146 AIEMATGTAPYHK--YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQK 203 + G P+ + L+ Q + P+ + +I L+ Sbjct: 203 LFALLLGNTPWDEAISNTGDYLLYKKQCERPSY-------HPWNLLSPGAYSIITGMLRS 255 Query: 204 DPTKRPTATELLKHPF 219 DP KR + +++HP+ Sbjct: 256 DPFKRYSVKHVVQHPW 271 >SPCC1919.01 |ppk34|SPCC830.12|serine/threonine protein kinase Ppk34|Schizosaccharomyces pombe|chr 3|||Manual Length = 354 Score = 70.1 bits (164), Expect = 8e-13 Identities = 51/181 (28%), Positives = 88/181 (48%), Gaps = 21/181 (11%) Query: 57 KEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 ++++ + Y H G IHRD+K NIL E+ + + DFG++ +L + Sbjct: 182 RQLVLAVNYIHGKGVIHRDIKPDNILFKENNNLCVIDFGLAEFLPKDGFVKPAS------ 235 Query: 117 GTPCWMAPEVMEQD--HGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPP 174 GTP +MAPE+ + + DIWS G+T +A P++ + ++ Sbjct: 236 GTPAFMAPELFDNELKKIKGKPLDIWSMGVTLYVIAFAEFPFNGSTILDMI--------- 286 Query: 175 NLDTGAEEKDQYKAY-GKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQTL 233 N+ G + AY RK++ CL+K+P KR T ELL+ PF + + + +LT + Sbjct: 287 NVIKG--KSLMIPAYCNSDLRKLLERCLEKNPEKRITIEELLRDPFLTE-RGKHHLTSSS 343 Query: 234 V 234 + Sbjct: 344 I 344 >SPCC70.05c |||serine/threonine protein kinase |Schizosaccharomyces pombe|chr 3|||Manual Length = 781 Score = 68.9 bits (161), Expect = 2e-12 Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 2/106 (1%) Query: 55 VLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT-GRDMSRQKVRH 113 ++K++L+GL Y HS G HRD+K NIL+ E G +++ DFG L G D++ + + Sbjct: 564 MIKQILRGLNYIHSQGIAHRDIKPENILISEYGVLRITDFGACDVLCNPGDDITAVESKS 623 Query: 114 TFV-GTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHK 158 + G+ +MAPE++ F AD+WS I + T P+ K Sbjct: 624 MGIFGSDPYMAPEILTPGSYNAFFADMWSTAIVLHCLYFRTYPFRK 669 >SPAC19E9.02 |fin1||serine/threonine protein kinase Fin1|Schizosaccharomyces pombe|chr 1|||Manual Length = 722 Score = 68.9 bits (161), Expect = 2e-12 Identities = 48/164 (29%), Positives = 78/164 (47%), Gaps = 16/164 (9%) Query: 64 EYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWM 122 E FH + HRD+K NI L E+ +V+L DFG+S L R ++ ++VGTP +M Sbjct: 139 EIFHPKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLLDNTRVFTQ-----SYVGTPYYM 193 Query: 123 APEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEE 182 +PE++ Y K+D+W+ G E+ T P+ +++ Q NL Sbjct: 194 SPEIIRSSP-YSAKSDVWALGCVIFEICMLTHPFEGRSYLELQRNICQG---NLSCW--- 246 Query: 183 KDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226 D + Y +I CL+ + RPT +LL+ P + + Sbjct: 247 -DHH--YSDDVFLLIRHCLEVNSDLRPTTYQLLRSPILSDIRSK 287 >SPBC1778.10c |ppk21|SPBC4C3.11|serine/threonine protein kinase Ppk21|Schizosaccharomyces pombe|chr 2|||Manual Length = 550 Score = 68.5 bits (160), Expect = 2e-12 Identities = 41/133 (30%), Positives = 67/133 (50%), Gaps = 5/133 (3%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMS 107 DE + E+L +EY HS G IHRD+K NIL + V++ DFG + L S Sbjct: 151 DENCVRFYAAEILSSIEYMHSCGIIHRDLKPENILFDGNMHVKITDFGTAKILPPKYVNS 210 Query: 108 RQKVR--HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165 +FVGT ++APE++ + +D+W+F +M G+ P+H P + Sbjct: 211 PDYTTFPSSFVGTAEYVAPELLSR-QVVSKSSDLWAFACVVYQMIVGSPPFHGSNPNNIF 269 Query: 166 --MLTLQNDPPNL 176 +++L+ + P L Sbjct: 270 KKIMSLEYELPKL 282 >SPBC32C12.03c |ppk25||serine/threonine protein kinase Ppk25 |Schizosaccharomyces pombe|chr 2|||Manual Length = 423 Score = 68.1 bits (159), Expect = 3e-12 Identities = 57/205 (27%), Positives = 92/205 (44%), Gaps = 19/205 (9%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDG-TVQLADFGVSAWLATG 103 G DE + +++ L Y H N +HRD+K N+LL +D V+L DFG+S + Sbjct: 145 GKLDEDLARSFAMQLINALVYLHKNFIVHRDLKIENVLLTQDSRQVKLIDFGLSNF---- 200 Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163 S+ + T+ G+ + APE+++ + D+WS G+ M G P + + Sbjct: 201 --YSKDDLLRTYCGSLYFAAPELLDAKPYIGPEVDVWSLGVVIYVMVCGRVP---FDDVS 255 Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223 V ML + +G E Y + +I L +P KR + + K P+ KK Sbjct: 256 VPML-----HSKIKSGKLEFPSY--ISEDCCSLIAAMLNVNPRKRCSLEQAAKFPWLKKN 308 Query: 224 KDRKYLTQTLVAI--GPSMETRVTK 246 YL L +I PS+ + V K Sbjct: 309 SFCLYLPIPLTSIPSTPSIRSHVFK 333 >SPAC2F3.15 |lsk1||latrunculin sensitive kinase Lsk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 67.7 bits (158), Expect = 4e-12 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 6/107 (5%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F I + K++ + L Y H G +HRD+K NILL +G ++ ADFG++ + + Sbjct: 371 FTPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNGDLKFADFGLARF-----NT 425 Query: 107 SRQKVRHTFVGTPCWM-APEVMEQDHGYDFKADIWSFGITAIEMATG 152 S + +T W PE++ + YD DIWS G +E+ TG Sbjct: 426 SSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTG 472 >SPCC18B5.03 |wee1||dual specificity protein kinase Wee1|Schizosaccharomyces pombe|chr 3|||Manual Length = 877 Score = 67.3 bits (157), Expect = 6e-12 Identities = 37/103 (35%), Positives = 59/103 (57%), Gaps = 8/103 (7%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMS 107 DE + +L EV GL++ H +H D+K N+++ +GT+++ DFG+++ R M Sbjct: 666 DEFRVWKILVEVALGLQFIHHKNYVHLDLKPANVMITFEGTLKIGDFGMASVWPVPRGME 725 Query: 108 RQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMA 150 R+ G ++APEV+ +H YD ADI+S GIT E A Sbjct: 726 RE-------GDCEYIAPEVL-ANHLYDKPADIFSLGITVFEAA 760 >SPAC110.01 |ppk1|SPAC140.05|serine/threonine protein kinase Ppk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1023 Score = 67.3 bits (157), Expect = 6e-12 Identities = 43/146 (29%), Positives = 68/146 (46%), Gaps = 17/146 (11%) Query: 24 VIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILL 83 V GG L D I + R+ +++ + +++ G+ Y HS G +HRD+K NILL Sbjct: 580 VNGGELFDYILARRRL--------EDSVACRLFAQLISGVAYLHSRGVVHRDLKLENILL 631 Query: 84 GEDGTVQLADFGVSAWLATGRDMSRQKVR-------HTFVGTPCWMAPEVMEQDHGY--D 134 + + +ADFG + +S + T G+PC+ APE++ G Sbjct: 632 DTNRNIVIADFGFATTFGHFNTLSEHSLPTEKPDLFSTSCGSPCYAAPELVNCKSGMYAG 691 Query: 135 FKADIWSFGITAIEMATGTAPYHKYP 160 +ADIWS G+ M G P+ P Sbjct: 692 TQADIWSCGVILYAMLAGYLPFDDDP 717 >SPBC21.07c |ppk24||serine/threonine protein kinase Ppk24|Schizosaccharomyces pombe|chr 2|||Manual Length = 461 Score = 66.9 bits (156), Expect = 7e-12 Identities = 35/101 (34%), Positives = 52/101 (51%) Query: 56 LKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTF 115 LK++L+ + Y S HRD+K NIL+G DG ++L DFG S + D + Sbjct: 237 LKQILQAVAYLQSQRIAHRDLKPENILIGRDGLLKLTDFGTSEIVGNPGDNESIRFVSGA 296 Query: 116 VGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 VG+ ++APE ++ AD WS GI + TG P+ Sbjct: 297 VGSLAYLAPEAFHENEYCGLLADRWSCGILLKVLFTGYFPF 337 >SPAC3C7.06c |pit1||serine/threonine protein kinase Pit1|Schizosaccharomyces pombe|chr 1|||Manual Length = 650 Score = 65.7 bits (153), Expect = 2e-11 Identities = 34/105 (32%), Positives = 61/105 (58%), Gaps = 11/105 (10%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDG-----TVQLADFGVSAWLATGRDM 106 + +++++ KGL + H+NG HRD+K NIL+ + V++ADFG++ R++ Sbjct: 138 VQDIMRQIFKGLNHIHTNGFFHRDMKPENILISSNSDSSSFNVKIADFGLA------REI 191 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMAT 151 + + +V T + APE++ +D Y F DI++ G A E+AT Sbjct: 192 NSRPPYTEYVSTRWYRAPELLLRDSYYSFPVDIYAAGCMAFEIAT 236 >SPCC4G3.08 |psk1||serine/threonine protein kinase Psk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 436 Score = 65.7 bits (153), Expect = 2e-11 Identities = 37/108 (34%), Positives = 55/108 (50%), Gaps = 7/108 (6%) Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108 E +A E+ L + H G ++RD+K N LL +G + L DFG+S G D Sbjct: 189 EDVVAFYTAELTLALIHLHKLGIVYRDLKPENCLLDAEGHILLTDFGLSKVAENGADC-- 246 Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 +FVGT + APE++ + YD D WS GI ++ TG+ P+ Sbjct: 247 ----RSFVGTEEYCAPEIL-LEQPYDHAVDWWSMGILIFDLLTGSPPF 289 >SPAC31G5.09c |spk1||MAP kinase Spk1|Schizosaccharomyces pombe|chr 1|||Manual Length = 372 Score = 65.3 bits (152), Expect = 2e-11 Identities = 53/183 (28%), Positives = 83/183 (45%), Gaps = 23/183 (12%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVG 117 ++L+ L+ HS G +HRD+K N+LL + +++ADFG++ +T +V Sbjct: 146 QILRALKAMHSAGVVHRDLKPSNLLLNANCDLKVADFGLAR--STTAQGGNPGFMTEYVA 203 Query: 118 TPCWMAPEVMEQDHGYDFKADIWSFGITAIEM--ATGTAPYHKYPPMKVLMLTLQNDPPN 175 T + APE+M Y D+WS G EM A P Y L+L + P Sbjct: 204 TRWYRAPEIMLSFREYSKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTM 263 Query: 176 LDTGAEEKDQYKAYGK--------TFRKMI-------VDCLQK----DPTKRPTATELLK 216 D + + + Y K +F+ + +D L+K +P KR TA E LK Sbjct: 264 DDFSRIKSARARKYIKSLPFTPKVSFKALFPQASPDAIDLLEKLLTFNPDKRITAEEALK 323 Query: 217 HPF 219 HP+ Sbjct: 324 HPY 326 >SPBC19F8.07 |crk1|mop1, mcs6|cyclin-dependent kinase activating kinase Crk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 335 Score = 65.3 bits (152), Expect = 2e-11 Identities = 39/111 (35%), Positives = 56/111 (50%), Gaps = 7/111 (6%) Query: 46 VFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRD 105 VF A I + + +L+GL + HS +HRD+K N+L+ DG ++LADFG+S T Sbjct: 104 VFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNNLLISSDGVLKLADFGLSRDFGTPSH 163 Query: 106 MSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 MS Q + T + PE+ Y D+WS G E+ T PY Sbjct: 164 MSHQVI------TRWYRPPELFMGCRSYGTGVDMWSVGCIFAELMLRT-PY 207 >SPAC57A10.02 |cdr2||GIN4 family protein kinase Cdr2|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 65.3 bits (152), Expect = 2e-11 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 18/176 (10%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G F E A L ++L GLEY H HRD+K N+ L G++++ +FG+++ G Sbjct: 103 GSFTEQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPG- 161 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYD-FKADIWSFGITAIEMATGTAPYHKYPPMK 163 K+ T G+P + +PE++ YD +DIWS GI + TG P+ ++ Sbjct: 162 -----KLLQTSCGSPHYASPEII-MGRSYDGCASDIWSCGIIFFALLTGKLPFDD-DNIR 214 Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219 L+L + + + + Q+ Y +M L D + R T ++ +HPF Sbjct: 215 SLLLKVCQGQFEMPSNISPQAQHLLY-----RM----LDVDSSTRITMEQIREHPF 261 >SPCC74.03c |ssp2|ucp9|serine/threonine protein kinase Ssp2|Schizosaccharomyces pombe|chr 3|||Manual Length = 576 Score = 64.9 bits (151), Expect = 3e-11 Identities = 58/198 (29%), Positives = 92/198 (46%), Gaps = 30/198 (15%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85 GG L D I K R++ DE ++++ +EY H + +HRD+K N+LL + Sbjct: 115 GGELFDYIVEKKRMTE------DEGR--RFFQQIICAIEYCHRHKIVHRDLKPENLLLDD 166 Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145 + V++ADFG+S + G + T G+P + APEV+ + D+WS GI Sbjct: 167 NLNVKIADFGLSNIMTDGNFLK------TSCGSPNYAAPEVINGKLYAGPEVDVWSCGIV 220 Query: 146 AIEMATGTAPY-HKYPP--MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202 M G P+ ++ P K + + P L GA+ R+MIV Sbjct: 221 LYVMLVGRLPFDDEFIPNLFKKVNSCVYVMPDFLSPGAQ---------SLIRRMIV---- 267 Query: 203 KDPTKRPTATELLKHPFF 220 DP +R T E+ + P+F Sbjct: 268 ADPMQRITIQEIRRDPWF 285 >SPAC24B11.06c |sty1|spc1, phh1|MAP kinase Sty1|Schizosaccharomyces pombe|chr 1|||Manual Length = 349 Score = 64.9 bits (151), Expect = 3e-11 Identities = 46/137 (33%), Positives = 70/137 (51%), Gaps = 17/137 (12%) Query: 16 EDDYEIGDVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRD 75 ED Y + +++G L H++ S + F I L ++L+GL++ HS G IHRD Sbjct: 91 EDIYFVTELLGTDL-----HRLLTSRPLETQF----IQYFLYQILRGLKFVHSAGVIHRD 141 Query: 76 VKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDF 135 +K NIL+ E+ +++ DFG LA +D +V T + APE+M Y+ Sbjct: 142 LKPSNILINENCDLKICDFG----LARIQDPQMT----GYVSTRYYRAPEIMLTWQKYNV 193 Query: 136 KADIWSFGITAIEMATG 152 + DIWS G EM G Sbjct: 194 EVDIWSAGCIFAEMIEG 210 >SPBC119.08 |pmk1|spm1|MAP kinase Pmk1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 422 Score = 64.5 bits (150), Expect = 4e-11 Identities = 33/105 (31%), Positives = 54/105 (51%), Gaps = 1/105 (0%) Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108 +A + + ++L GL+Y HS IHRD+K GN+L+ D +++ DFG++ + + Sbjct: 123 DAHFQSFIYQILCGLKYIHSANVIHRDLKPGNLLVNADCELKICDFGLARGCSENPE-EN 181 Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGT 153 +V T + APE+M Y D+WS G E+ GT Sbjct: 182 PGFMTEYVATRWYRAPEIMLSFSSYHKGIDVWSVGCILAELLGGT 226 >SPCC16C4.11 |pef1||Pho85/PhoA-like cyclin-dependent kinase Pef1|Schizosaccharomyces pombe|chr 3|||Manual Length = 288 Score = 62.9 bits (146), Expect = 1e-10 Identities = 34/108 (31%), Positives = 55/108 (50%), Gaps = 5/108 (4%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G + + +++LKG+ + H N +HRD+K N+L+ G ++LADFG++ + Sbjct: 96 GALPPSQVKNFTQQLLKGISFCHENRVLHRDLKPQNLLINSRGELKLADFGLARSIGIPV 155 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATG 152 + + V T + AP+V+ Y DIWS G EMATG Sbjct: 156 NTFSNE-----VVTLWYRAPDVLLGSRVYSTSIDIWSVGCIMAEMATG 198 >SPBC11B10.09 |cdc2|swo2|cyclin-dependent protein kinase Cdc2|Schizosaccharomyces pombe|chr 2|||Manual Length = 297 Score = 61.7 bits (143), Expect = 3e-10 Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 5/120 (4%) Query: 30 LDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTV 89 +D+ K+ R+S D + +++ G+ + HS IHRD+K N+L+ ++G + Sbjct: 89 MDLKKYMDRISETGATSLDPRLVQKFTYQLVNGVNFCHSRRIIHRDLKPQNLLIDKEGNL 148 Query: 90 QLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEM 149 +LADFG LA + + H V T + APEV+ Y DIWS G EM Sbjct: 149 KLADFG----LARSFGVPLRNYTHEIV-TLWYRAPEVLLGSRHYSTGVDIWSVGCIFAEM 203 >SPBC106.01 |mph1|SPBC1271.16c, SPBC243.01|dual specificity protein kinase Mph1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 678 Score = 60.9 bits (141), Expect = 5e-10 Identities = 50/184 (27%), Positives = 86/184 (46%), Gaps = 26/184 (14%) Query: 57 KEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 +++L+ ++ H +H D+K N LL E G ++L DFG++ A G D + R + + Sbjct: 424 EQMLEAVQVVHDQNIVHSDLKPANFLLVE-GNLKLIDFGIAK--AIGNDTTNIH-RDSHI 479 Query: 117 GTPCWMAPEVMEQDHGYDFK----------ADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 GT +MAPE + + + +D+WS G +M G AP+ ++ + Sbjct: 480 GTINYMAPEALTDMNAHTNSGVKLVKLGRPSDVWSLGCILYQMVYGRAPFAHLKMIQAIA 539 Query: 167 LTLQNDPPN-------LDTGAEEKDQYKAYGKTFRKMIVD----CLQKDPTKRPTATELL 215 + N+ + L A ++ + G T ++D CL++D KR T ELL Sbjct: 540 -AIPNEQYHIHFPEVALPANAVQEKEGSLPGVTVGPDLMDVMKRCLERDQRKRLTIPELL 598 Query: 216 KHPF 219 HPF Sbjct: 599 VHPF 602 >SPBC6B1.02 |ppk30||Ark1/Prk1 family protein kinase Ppk30|Schizosaccharomyces pombe|chr 2|||Manual Length = 953 Score = 60.5 bits (140), Expect = 6e-10 Identities = 54/217 (24%), Positives = 95/217 (43%), Gaps = 30/217 (13%) Query: 12 WSNTEDDYEIGDVI----GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFH 67 +S +E+ YE+ ++ GG L+D + +++ E I +L +V + H Sbjct: 124 YSKSENRYEVYLLMEFCAGGGLIDFMNTRLQHR------LTEGEILKILADVCDAVAAMH 177 Query: 68 --SNGQIHRDVKAGNILLGEDGTVQLADFGVS----AWLATGRDMSRQKVRHTFVGTPCW 121 IHRD+K N+LL + +L DFG + A T + + TP + Sbjct: 178 YLDPPLIHRDLKIENVLLVAPNSYKLCDFGSACEPLAPATTPDTIMFLEQNIAAYTTPQY 237 Query: 122 MAPEVME--QDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTG 179 APE+++ + G D K+DIW+ G+ A ++ T P+ + +L + P Sbjct: 238 RAPEMIDINRRQGIDEKSDIWAIGVLAYKLCYYTTPFEQVGNSAILKASFSFPP------ 291 Query: 180 AEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216 + Y ++ I CLQ+ P+ RP + LK Sbjct: 292 ------FPRYSDRMKRFIATCLQEQPSHRPNIYQTLK 322 >SPCC63.08c |ppk36|atg1|serine/threonine protein kinase Ppk36|Schizosaccharomyces pombe|chr 3|||Manual Length = 830 Score = 60.5 bits (140), Expect = 6e-10 Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 26/141 (18%) Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGT------------------V 89 +E + +++ L++ S IHRDVK N+LL T + Sbjct: 130 NETLVRHFTQQLASALQFLRSRSLIHRDVKPQNLLLQPPPTAAYLEEHPQFVGSPKLPML 189 Query: 90 QLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEM 149 +LADFG + +L T + T G+P +MAPE++ + YD KAD+WS G EM Sbjct: 190 KLADFGFARYLQTS------SMAETLCGSPLYMAPEILRYEK-YDAKADLWSVGAVLYEM 242 Query: 150 ATGTAPYHKYPPMKVLMLTLQ 170 A G P+ K P L+ +Q Sbjct: 243 AVGKPPF-KAPNHVELLRRIQ 262 >SPBC18H10.15 |ppk23||serine/threonine protein kinase Ppk23|Schizosaccharomyces pombe|chr 2|||Manual Length = 398 Score = 59.7 bits (138), Expect = 1e-09 Identities = 57/232 (24%), Positives = 100/232 (43%), Gaps = 32/232 (13%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F ++ + T++ ++L + H + +HRD+K N+L+ G ++LADFG++ R + Sbjct: 170 FLQSEVKTLMLQLLAATAFMHHHWYLHRDLKPSNLLMNNTGEIKLADFGLA------RPV 223 Query: 107 SRQKVRHTFVGTPCW-MAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY--------- 156 S K T + W APE++ Y + D+WS G EM T T + Sbjct: 224 SEPKSSLTRLVVTLWYRAPELLLGAPSYGKEIDMWSIGCIFAEMITRTPLFSGKSELDQL 283 Query: 157 ------------HKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKD 204 ++P +L + P + T ++ + ++ L + Sbjct: 284 YKIFNLLGYPTREEWPQYFLLPYANKIKHPTVPTHSKIRTSIPNLTGNAYDLLNRLLSLN 343 Query: 205 PTKRPTATELLKHPFF---KKAKDRKYL-TQTLVAIGPSMETRVTKASKKHS 252 P KR +A E L+HP+F + KD K+ T A G S E V ++ + S Sbjct: 344 PAKRISAKEALEHPYFYESPRPKDPKFFPTFPSKAKGESKEKNVFQSFRSAS 395 >SPAPB18E9.02c |ppk18||serine/threonine protein kinase Ppk18 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1316 Score = 58.0 bits (134), Expect = 3e-09 Identities = 28/72 (38%), Positives = 42/72 (58%) Query: 56 LKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTF 115 + EV GLE+ H G IHRD+K NIL+ G ++LADFG+S T R + QK ++ Sbjct: 669 IAEVALGLEHLHRLGIIHRDIKPDNILMSITGHLKLADFGLSQLGLTTRQLRLQKGKNNI 728 Query: 116 VGTPCWMAPEVM 127 + P + +P + Sbjct: 729 LSPPSFQSPTAL 740 Score = 42.7 bits (96), Expect = 1e-04 Identities = 32/109 (29%), Positives = 47/109 (43%), Gaps = 10/109 (9%) Query: 115 FVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPP 174 FVGTP ++APE + + D D W+ G E G P+H P KV L N Sbjct: 831 FVGTPDYLAPETL-RGSTQDDMVDWWALGCVLFEFLFGYPPFHAETPEKVFENILAN--- 886 Query: 175 NLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKR---PTATELLKHPFF 220 + + + Y + +I LQ +P +R E+ +HPFF Sbjct: 887 --NIAWPDLEMYPCSEEAL-DLINGFLQPNPERRLGFSDINEIKEHPFF 932 >SPAC22G7.08 |ppk8||serine/threonine protein kinase Ppk8 |Schizosaccharomyces pombe|chr 1|||Manual Length = 513 Score = 57.6 bits (133), Expect = 5e-09 Identities = 42/120 (35%), Positives = 63/120 (52%), Gaps = 6/120 (5%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVG 117 ++L G+ Y HS G HRD+K NI+L E+ V++ DFG +A++ S + VG Sbjct: 347 QLLDGVAYMHSLGIAHRDIKLDNIMLDENLNVKIIDFG-TAFVFHYPFESTTLMSDGVVG 405 Query: 118 TPCWMAPEVMEQDHGYDFKA-DIWSFGITAIEMATGTAPY---HKYPPMKVLMLTLQNDP 173 + ++APEV+ Q YD A D+WS I +A P+ H L +T +NDP Sbjct: 406 SKPYVAPEVLTQ-KPYDPSAVDVWSCAIVYCCIALKRFPWKVPHTSDKRFNLYVTQRNDP 464 >SPBC660.14 |mik1||mitotic inhibitor kinase Mik1|Schizosaccharomyces pombe|chr 2|||Manual Length = 581 Score = 57.2 bits (132), Expect = 6e-09 Identities = 35/106 (33%), Positives = 55/106 (51%), Gaps = 8/106 (7%) Query: 46 VFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRD 105 V D + +L ++ + L + H +H DVK N+L+ DG ++L DFG LAT Sbjct: 388 VMDPFRVWKMLFQLTQALNFIHLLEFVHLDVKPSNVLITRDGNLKLGDFG----LATSLP 443 Query: 106 MSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMAT 151 +S G ++APE++ H Y AD++S G++ IE AT Sbjct: 444 VSSMV---DLEGDRVYIAPEIL-ASHNYGKPADVYSLGLSMIEAAT 485 >SPBC16E9.13 |ksp1|ppk20|serine/threonine protein kinase Ksp1 |Schizosaccharomyces pombe|chr 2|||Manual Length = 474 Score = 56.8 bits (131), Expect = 8e-09 Identities = 39/121 (32%), Positives = 63/121 (52%), Gaps = 19/121 (15%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNIL--LGEDGT---VQLADFGVSAWLATGRDM 106 I + +++ G+ + HS+G HRD+K N L L EDG+ V+++DFG++ Sbjct: 114 IKNIFLQIIDGVAHLHSHGIYHRDLKPENFLLSLSEDGSELVVKISDFGLAC-------- 165 Query: 107 SRQKVRHTF-VGTPCWMAPEVMEQDHGYDFK---ADIWSFGITAIEMATGTAPYHKYPPM 162 R K+ + F G+ +MAPE E+ G + ADIW+ GI + + P+ YP Sbjct: 166 -RDKISYDFGTGSDRYMAPEQFEEVDGAGYSPRAADIWALGICLLNLIFARNPF-TYPHE 223 Query: 163 K 163 K Sbjct: 224 K 224 >SPAC1687.15 |gsk3|skp1|serine/threonine protein kinase Gsk3|Schizosaccharomyces pombe|chr 1|||Manual Length = 387 Score = 56.8 bits (131), Expect = 8e-09 Identities = 51/188 (27%), Positives = 84/188 (44%), Gaps = 26/188 (13%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLG-EDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 ++L+ L Y H++G HRD+K N+LL E+G ++L DFG + L G + +++ Sbjct: 140 QLLRSLAYIHASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAG------EPNVSYI 193 Query: 117 GTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATG--TAPYHKYPPMKVLMLTLQNDP- 173 + + APE++ Y DIWS G E+ G P V ++ + P Sbjct: 194 CSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPS 253 Query: 174 --------PNLDTGAEEKDQYKAYGKTFRKMI----VDCLQK----DPTKRPTATELLKH 217 PN + + + + F + + +D L K PT R TA E + H Sbjct: 254 REQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVPLDALDLLSKMLQYTPTDRLTAAEAMCH 313 Query: 218 PFFKKAKD 225 PFF + +D Sbjct: 314 PFFDELRD 321 >SPAC23C11.11 |cka1|orb5|serine/threonine protein kinase Cka1|Schizosaccharomyces pombe|chr 1|||Manual Length = 332 Score = 56.4 bits (130), Expect = 1e-08 Identities = 29/88 (32%), Positives = 50/88 (56%), Gaps = 7/88 (7%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLG-EDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 E+LK L++ HS G +HRDVK N+++ + ++L D+G++ + G + + + F Sbjct: 143 ELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFK 202 Query: 117 GTPCWMAPEVMEQDHGYDFKADIWSFGI 144 G PE++ YD+ DIWSFG+ Sbjct: 203 G------PELLVDFREYDYSLDIWSFGV 224 >SPAC1D4.06c |csk1||cyclin-dependent kinase activating kinase Csk1 |Schizosaccharomyces pombe|chr 1|||Manual Length = 306 Score = 56.4 bits (130), Expect = 1e-08 Identities = 39/116 (33%), Positives = 58/116 (50%), Gaps = 6/116 (5%) Query: 43 VNGVFDEATIATVLKEVLK---GLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSA 98 ++ V DE +I T K VL+ LEY +G +HRD+ NILL +G L+DF + A Sbjct: 94 LSDVMDEISIDTKCKIVLQISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSI-A 152 Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTA 154 W Q++ +GT + A E + H Y + D W+FGI E+ + A Sbjct: 153 WSKQHPGEEVQELIPQ-IGTGHYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQA 207 >SPBC1861.09 |ppk22||serine/threonine protein kinase Ppk22 |Schizosaccharomyces pombe|chr 2|||Manual Length = 526 Score = 55.6 bits (128), Expect = 2e-08 Identities = 57/190 (30%), Positives = 84/190 (44%), Gaps = 32/190 (16%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVS----------AWLATGRDMS 107 EV LEY H G I+RD+K NILL + G + L+DF +S L S Sbjct: 263 EVTAALEYLHLMGFIYRDLKPENILLHQSGHIMLSDFDLSKPISIVTHPTVVLPKHSTFS 322 Query: 108 RQKV------------RHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155 ++K ++FVGT ++APEV+ + G+ D W+ GI E+ GT P Sbjct: 323 QEKPALDTNSYFSNFRTNSFVGTEEYIAPEVI-RSCGHTVAVDWWTLGIFIYEILYGTTP 381 Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKR----PTA 211 + K T N + D E T + +I L KD +KR A Sbjct: 382 FKG----KNRHATFSNILYS-DVSFPEYHGAPNVSSTCKSLIRRLLVKDESKRCGSVAGA 436 Query: 212 TELLKHPFFK 221 +++ +HPFF+ Sbjct: 437 SDIKQHPFFR 446 >SPBC32H8.10 |cdk9||cyclin-dependent protein kinase Cdk9 |Schizosaccharomyces pombe|chr 2|||Manual Length = 591 Score = 55.2 bits (127), Expect = 2e-08 Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 8/114 (7%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F E I +K++ G +Y H +HRD+KA N+L+ G +++ADFG++ + Sbjct: 138 FTEPQIKCYMKQLFAGTKYLHDQLILHRDLKAANLLIDNHGILKIADFGLARVITEESYA 197 Query: 107 SRQ-----KVRHTFVG---TPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATG 152 ++ R + G T + +PE++ + Y D+WS G EM G Sbjct: 198 NKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKG 251 >SPAC29A4.16 |hal4|sat4, ppk10|halotolerence protein 4|Schizosaccharomyces pombe|chr 1|||Manual Length = 636 Score = 55.2 bits (127), Expect = 2e-08 Identities = 41/164 (25%), Positives = 78/164 (47%), Gaps = 11/164 (6%) Query: 57 KEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 K++++G++Y H G HRD+K N+LL G++++ DFG M+ +K H Sbjct: 463 KQLMRGVDYLHDMGVAHRDLKPENLLLTVSGSLKITDFGNGECFR----MAWEKEAHMTC 518 Query: 117 GTPCWMAPEVMEQDH---GYDFKA-DIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172 G C AP + +++ +D +A D+W+ G+ + M TG + + + Sbjct: 519 GL-CGSAPYIAPEEYTESEFDPRAVDVWACGVIYMAMRTGRHLWRVAKKSEDEYYSRYLM 577 Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216 ++G E + + R + + L +PT R TA +++K Sbjct: 578 DRKNESGYEPIEMLER--SRCRNTLYNILHPNPTYRLTAKQIMK 619 >SPBC557.04 |ppk29||Ark1/Prk1 family protein kinase Ppk29|Schizosaccharomyces pombe|chr 2|||Manual Length = 872 Score = 54.0 bits (124), Expect = 6e-08 Identities = 48/199 (24%), Positives = 90/199 (45%), Gaps = 29/199 (14%) Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFH--SNGQIHRDVKAGNILL 83 GG L+D + +++ E + ++ ++++G+ H IHRD+K N+LL Sbjct: 118 GGGLIDFMNQRLQTR------LSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLL 171 Query: 84 GEDGTVQLADFG-VSAWLATGRDMSR----QKVRHTFVGTPCWMAPEVME--QDHGYDFK 136 + T +L DFG V+ + + S +K +TF T + APE++ G D K Sbjct: 172 SFN-TFKLCDFGSVTEPMHAAENSSEIQALEKSINTFT-TYQYRAPEMINLYSGLGIDEK 229 Query: 137 ADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKM 196 +D+W+ G+ ++ T P+ P +L + P + Y + + + Sbjct: 230 SDMWALGVLLYKLCYYTTPFETQGPNAILTASYSFPP------------FPPYSHSLKNV 277 Query: 197 IVDCLQKDPTKRPTATELL 215 I+ LQ +P RP +L+ Sbjct: 278 IIALLQPNPCLRPNIFQLM 296 >SPAC23H4.17c |srb10|prk1, cdk8|cyclin-dependent protein kinase Srb10 |Schizosaccharomyces pombe|chr 1|||Manual Length = 352 Score = 52.0 bits (119), Expect = 2e-07 Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 4/99 (4%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKV 111 + ++L +++ G+ Y H N +HRD+K NI++ G V++ D G+ + RD Sbjct: 117 LKSILWQIINGVAYLHENWIMHRDLKPANIMITATGKVKIGDLGLGRLI---RDPILPFY 173 Query: 112 RHTFVGTPCW-MAPEVMEQDHGYDFKADIWSFGITAIEM 149 V W APE++ H Y D+W+ G EM Sbjct: 174 SSDRVVVTIWYRAPELLLGAHDYTPAIDVWAIGCIYGEM 212 Score = 27.5 bits (58), Expect = 5.6 Identities = 12/29 (41%), Positives = 17/29 (58%) Query: 196 MIVDCLQKDPTKRPTATELLKHPFFKKAK 224 +++ LQ DP R TA + L+H FF K Sbjct: 295 LLMKMLQYDPKSRITAKQALEHVFFTSDK 323 >SPBC8D2.19 |mde3||serine/threonine protein kinase Mde3|Schizosaccharomyces pombe|chr 2|||Manual Length = 559 Score = 51.6 bits (118), Expect = 3e-07 Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 14/112 (12%) Query: 46 VFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNIL--------LGEDGTVQLADFGVS 97 +F + T +L +++ G+E+ H +G +HRD+K NIL + +++L DFG++ Sbjct: 121 LFTKETAFNILLQIISGIEHIHKHGFMHRDIKPENILVKRISPKPISSRYSIKLGDFGLA 180 Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEM 149 + ++ +V T + APE++ + Y+ D+++FG E+ Sbjct: 181 RPSVSSDPLTE------YVSTRWYRAPELLLRSGSYNHSVDLYAFGCIVFEI 226 >SPCC1020.10 |oca2||serine/threonine protein kinase Oca2 |Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 51.6 bits (118), Expect = 3e-07 Identities = 37/108 (34%), Positives = 57/108 (52%), Gaps = 6/108 (5%) Query: 57 KEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHT-F 115 K++L G+ Y HS G HRD+K N+++ + V++ DFG + + V T Sbjct: 407 KQLLSGVAYLHSMGLAHRDLKLDNLVVDSNCFVKIIDFGSA--VVFKYPFEADIVEATGV 464 Query: 116 VGTPCWMAPEVMEQDHGYDFKA-DIWSFGITAIEMATGTAPYHKYPPM 162 VG+ ++APE + + YD +A DIWS I MA P+ KYP + Sbjct: 465 VGSDPYLAPETLVRKL-YDPRAVDIWSSAIIFCCMALRRFPW-KYPKL 510 >SPAC4G8.05 |ppk14||serine/threonine protein kinase Ppk14 |Schizosaccharomyces pombe|chr 1|||Manual Length = 566 Score = 51.6 bits (118), Expect = 3e-07 Identities = 50/191 (26%), Positives = 77/191 (40%), Gaps = 24/191 (12%) Query: 56 LKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVS------------------ 97 + EV LEY H G I+RD+K NILL E G + L+DF +S Sbjct: 301 IAEVTAALEYLHLMGFIYRDLKPENILLHESGHIMLSDFDLSKQSNSAGAPTVIQARNAP 360 Query: 98 ----AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGT 153 A+ + ++FVGT ++APEV+ + G+ D W+ GI EM T Sbjct: 361 SAQNAYALDTKSCIADFRTNSFVGTEEYIAPEVI-KGCGHTSAVDWWTLGILFYEMLYAT 419 Query: 154 APYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213 P+ K + + + A+ RK++V + A + Sbjct: 420 TPF-KGKNRNMTFSNILHKDVIFPEYADAPSISSLCKNLIRKLLVKDENDRLGSQAGAAD 478 Query: 214 LLKHPFFKKAK 224 + HPFFK + Sbjct: 479 VKLHPFFKNVQ 489 >SPBC8D2.01 |gsk31||serine/threonine protein kinase Gsk31|Schizosaccharomyces pombe|chr 2|||Manual Length = 381 Score = 50.0 bits (114), Expect = 9e-07 Identities = 49/190 (25%), Positives = 79/190 (41%), Gaps = 30/190 (15%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLG-EDGTVQLADFGVSAWLATGRDMSRQKVRHTFV 116 ++ + L Y HS G HRD+K N+L+ + G ++L DFG + L S V +++ Sbjct: 133 QLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVP----SEPNV--SYI 186 Query: 117 GTPCWMAPEVMEQDHGYDFKADIWSFGITAIEM---------------------ATGTAP 155 + + APE++ Y K D+WS E+ GT Sbjct: 187 CSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPS 246 Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215 YH+ M + + PN+ E K ++ L P+KR +A E+L Sbjct: 247 YHEISVMNPNY--VNHSLPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVL 304 Query: 216 KHPFFKKAKD 225 HPFF + +D Sbjct: 305 THPFFDELRD 314 >SPAC1805.01c |ppk6|SPAPJ736.02c|serine/threonine protein kinase Ppk6|Schizosaccharomyces pombe|chr 1|||Manual Length = 775 Score = 50.0 bits (114), Expect = 9e-07 Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 7/100 (7%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVG 117 ++ + + HS IHRD+K N++L +G +L DFG S+ +++ TF G Sbjct: 619 QIALAVAHLHSFDIIHRDIKDENVILEGNGCARLIDFGSSS-------LTKNGPFDTFRG 671 Query: 118 TPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYH 157 T + APE++ + + DIW+ GI + PY+ Sbjct: 672 TVGFAAPELLRGEKYLGKEQDIWALGILLYTIVYRENPYY 711 >SPBC725.06c |ppk31|mug25|serine/threonine protein kinase Ppk31 |Schizosaccharomyces pombe|chr 2|||Manual Length = 1032 Score = 48.0 bits (109), Expect = 4e-06 Identities = 22/71 (30%), Positives = 38/71 (53%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G E + E+L +E H +G IH D+K N+L+ E G ++L DFG+S + + Sbjct: 622 GPLPEQWVCQYAAELLNAIELLHQDGIIHHDIKPANMLVDETGHIRLTDFGLSENVEEKK 681 Query: 105 DMSRQKVRHTF 115 ++ + R +F Sbjct: 682 EVYKLTKRMSF 692 Score = 46.8 bits (106), Expect = 8e-06 Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 7/119 (5%) Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFK-ADIWSFGITAIEMATGTAPYHKYPPMKVL 165 +R ++ GTP +MAPE++ G D + DIW+ G EM TGT P+ + +K + Sbjct: 769 NRTFIKKDISGTPNYMAPEILM---GVDTQMGDIWAMGCVIFEMLTGTRPF-EANTVKAI 824 Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAK 224 ++ + +E +A + M DC ++ + E+ KHPFF+ K Sbjct: 825 WARIERNDIGWTKRVKESCSKEAVDLITKLMDPDCNKRLGSN--GYQEIKKHPFFRTIK 881 >SPCC417.06c |ppk35|mug27|serine/threonine protein kinase Ppk35|Schizosaccharomyces pombe|chr 3|||Manual Length = 624 Score = 47.2 bits (107), Expect = 6e-06 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104 G+ E L E++ + H G +HRD+K N L+ + G ++L+DFG+S + T Sbjct: 255 GLLHENQTRFYLAEMVAAISAVHKLGYMHRDLKPENFLIDQKGHIKLSDFGLSTAIVTSN 314 Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKA 137 ++R ++H V P + ++ +KA Sbjct: 315 QVNR--LQHALVSAVNPQRPYLTQKQRRNIYKA 345 Score = 43.6 bits (98), Expect = 8e-05 Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY------HKYPPMKVLM 166 ++ VG+P +MAPEV+ YD D WS G E G P+ + + Sbjct: 355 NSVVGSPEYMAPEVV-YGKKYDRTVDYWSLGCICYECLVGYPPFSGSTLQETWTNLYYWR 413 Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222 LQ N + G +K + + I CL + ++ + E+ KHPFFK+ Sbjct: 414 EMLQRPSKN-ENGIYDKKARSVSDEAW-SFITKCLTEPTSRFQSTIEIQKHPFFKR 467 >SPAC24B11.11c |sid2||Sid2p-Mob1p kinase complex|Schizosaccharomyces pombe|chr 1|||Manual Length = 607 Score = 46.8 bits (106), Expect = 8e-06 Identities = 19/55 (34%), Positives = 33/55 (60%) Query: 58 EVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112 E+ ++ H G IHRD+K N L+G G ++L DFG+S+ + + + + K+R Sbjct: 314 EMFLAIDALHQLGYIHRDLKPENFLVGASGHIKLTDFGLSSGIISKKKIESMKIR 368 Score = 39.5 bits (88), Expect = 0.001 Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 H+ VG+P +MAPEV+ ++ Y+ D WS G E +G P+ Sbjct: 401 HSVVGSPDYMAPEVLRGEN-YNHSVDYWSLGCIMYECLSGFPPF 443 >SPAC3H1.13 |ppk13||serine/threonine protein kinase Ppk13 |Schizosaccharomyces pombe|chr 1|||Manual Length = 344 Score = 46.8 bits (106), Expect = 8e-06 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 15/152 (9%) Query: 72 IHRDVKAGNILLGEDGT-VQLADFG----VSAWLATGRDMSRQKVRHTFVGTPCWMAPEV 126 IH D+K N+LL E+ + L DFG V + + + + + + T + APE+ Sbjct: 191 IHGDIKPDNLLLHENSREIVLTDFGSICLVPIFASNNSEAIAIQDKASENCTMPFRAPEL 250 Query: 127 MEQDHGYDF--KADIWSFGITAIEMATGTAPYHKYPPM-KVLMLTLQNDPPNLDTGAEEK 183 G KADIWSFG T + +P+ + L L + N + Sbjct: 251 FHVKAGSTITEKADIWSFGCTLYTIMFHASPFEREVSQGGSLALAVCNAQYSF------- 303 Query: 184 DQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215 + Y +++ CLQ++P KRP+A ELL Sbjct: 304 PRKHPYSTLLCEIVEACLQREPNKRPSARELL 335 >SPCC1450.11c |cek1||serine/threonine protein kinase Cek1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1338 Score = 46.8 bits (106), Expect = 8e-06 Identities = 22/53 (41%), Positives = 32/53 (60%) Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVS 97 GV D I T + E + L H G IHRD+K N+L+ ++G ++L DFG+S Sbjct: 683 GVLDLDWIRTYIAETVLCLGDLHDRGIIHRDIKPENLLISQNGHLKLTDFGLS 735 Score = 38.7 bits (86), Expect = 0.002 Identities = 33/110 (30%), Positives = 48/110 (43%), Gaps = 10/110 (9%) Query: 115 FVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPP 174 F+GTP ++APEV+ + G +D WS G E G P++ P +V L Sbjct: 857 FIGTPDYIAPEVILGNPGIK-ASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILAR--- 912 Query: 175 NLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTAT---ELLKHPFFK 221 ++ AE + A +I L +P R A E+ HPFFK Sbjct: 913 RINWPAE---VFTAESSVALDLIDRLLCMNPANRLGANGVEEIKAHPFFK 959 >SPBC337.04 |ppk27||serine/threonine protein kinase Ppk27 |Schizosaccharomyces pombe|chr 2|||Manual Length = 413 Score = 46.4 bits (105), Expect = 1e-05 Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 20/126 (15%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE---------------DGTVQLADFGV 96 + + E++ + Y HS IHRD+K NILL + + +Q++DF + Sbjct: 208 VGRIFSELVHTVAYLHSKCLIHRDLKLENILLTQPYNVIKTIDNWKNYPNALIQISDFEL 267 Query: 97 SAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 S ++ S+ + + G+ + PEV F+AD WS GI + G P+ Sbjct: 268 SIFVD-----SKNHLVQSSCGSQEYAPPEVYMGIAHDGFRADAWSLGIVLFALLEGRLPF 322 Query: 157 HKYPPM 162 YP + Sbjct: 323 DSYPTL 328 >SPBC19C2.05 |ran1|pat1|serine/threonine protein kinase Ran1|Schizosaccharomyces pombe|chr 2|||Manual Length = 470 Score = 46.0 bits (104), Expect = 1e-05 Identities = 22/47 (46%), Positives = 32/47 (68%), Gaps = 1/47 (2%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED-GTVQLADFGVS 97 I TV +++ +E+ HS G HRD+K NI++G D TV LADFG++ Sbjct: 120 IKTVFLQLISAVEHCHSVGIYHRDLKPENIMVGNDVNTVYLADFGLA 166 >SPCP1E11.02 |ppk38||Ark1/Prk1 family protein kinase Ppk38|Schizosaccharomyces pombe|chr 3|||Manual Length = 650 Score = 44.8 bits (101), Expect = 3e-05 Identities = 33/138 (23%), Positives = 61/138 (44%), Gaps = 14/138 (10%) Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFH--SNGQIHRDVKAGNILLG 84 G L+D + +++V E I + +V + + H IHRD+K N+LL Sbjct: 122 GGLIDFLNTRLQVR------LSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLA 175 Query: 85 EDGTVQLADFGVSAWLATGRDMSRQ--KVRHTFVGTPCWM--APEVMEQDHGY--DFKAD 138 + +L DFG + G + + ++ + W PE++ G+ D K+D Sbjct: 176 APNSYKLCDFGSACHPIPGAKTAAEAKQLEYDIEKFTTWQYRCPEMINVHKGFGIDEKSD 235 Query: 139 IWSFGITAIEMATGTAPY 156 IW+ G+ ++ T P+ Sbjct: 236 IWALGVLFYKLCYYTTPF 253 >SPBC3H7.15 |hhp1||serine/threonine protein kinase Hhp1|Schizosaccharomyces pombe|chr 2|||Manual Length = 365 Score = 44.8 bits (101), Expect = 3e-05 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 12/93 (12%) Query: 10 IPWSNTEDDYE--IGDVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFH 67 + W E DY + D++G SL D+ N N F T+ + +++ +E+ H Sbjct: 70 VRWFGVECDYNAMVMDLLGPSLEDLF-------NFCNRKFSLKTVLLLADQLISRIEFIH 122 Query: 68 SNGQIHRDVKAGNILLG---EDGTVQLADFGVS 97 S +HRD+K N L+G V + DFG++ Sbjct: 123 SKSFLHRDIKPDNFLMGIGKRGNQVNIIDFGLA 155 >SPAC821.12 |orb6||serine/threonine protein kinase Orb6|Schizosaccharomyces pombe|chr 1|||Manual Length = 469 Score = 44.8 bits (101), Expect = 3e-05 Identities = 20/51 (39%), Positives = 29/51 (56%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVS 97 F E + E + + H G IHRD+K NIL+ DG ++L+DFG+S Sbjct: 188 FSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNILIDRDGHIKLSDFGLS 238 Score = 37.1 bits (82), Expect = 0.007 Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%) Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 +R+ + ++ VGTP ++APE+ Q GY D WS G E G P+ Sbjct: 284 NRRVMAYSTVGTPDYIAPEIFLQ-QGYGQDCDWWSLGAIMFECLIGWPPF 332 >SPAC644.06c |cdr1|nim1|GIN4 family protein kinase Cdr1|Schizosaccharomyces pombe|chr 1|||Manual Length = 593 Score = 44.0 bits (99), Expect = 6e-05 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 7/114 (6%) Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLG-EDGTVQLADFGVSAWLAT 102 +G E A L ++L + + H HRD+K NIL+ + +++ADFG +AT Sbjct: 97 HGPLSEREAAHYLSQILDAVAHCHRFRFRHRDLKLENILIKVNEQQIKIADFG----MAT 152 Query: 103 GRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPY 156 + G+ ++APE++ AD+WS G+ + + P+ Sbjct: 153 VEP--NDSCLENYCGSLHYLAPEIVSHKPYRGAPADVWSCGVILYSLLSNKLPF 204 >SPAC1D4.11c |lkh1|kic1|dual specificity protein kinase Lkh1|Schizosaccharomyces pombe|chr 1|||Manual Length = 690 Score = 43.2 bits (97), Expect = 1e-04 Identities = 35/150 (23%), Positives = 66/150 (44%), Gaps = 18/150 (12%) Query: 21 IGDVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGN 80 + D+ G S+ D +K+ + F I + +++ K + + HS G +H D+K N Sbjct: 440 VTDLFGWSVFDFLKNNNYIP------FPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPEN 493 Query: 81 ILLGEDG--TVQLADFGVSAWLAT---------GRDMSRQKVRHTFVGTPCWMAPEVMEQ 129 +LL + T++L S + G + + V T + APE++ Sbjct: 494 VLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEII-L 552 Query: 130 DHGYDFKADIWSFGITAIEMATGTAPYHKY 159 G+ + D+WS G +E+ TG A + + Sbjct: 553 GLGWSYPCDVWSIGCILVELFTGQALFQTH 582 Score = 27.9 bits (59), Expect = 4.2 Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 4/29 (13%) Query: 196 MIVDCLQK----DPTKRPTATELLKHPFF 220 +++D L+K DP +R TA E L HPFF Sbjct: 654 LLLDLLKKVFVYDPKRRITAKEALWHPFF 682 >SPAC12B10.14c |ppk2||serine/threonine protein kinase Ppk2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 665 Score = 42.7 bits (96), Expect = 1e-04 Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 17/174 (9%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDM 106 F E IA++ E+ GL + H++G H ++ I L + +++ ++ S+ R Sbjct: 480 FSELNIASICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSPYIE-RQT 538 Query: 107 SRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166 +R V H P W+ +E+++ F D+ S G+ A+E+ G + + + + Sbjct: 539 NRGAVSH----VPDWL----IEKNYKEGFMKDVKSLGLVALEIFQGQPNFFRKSIQSIQL 590 Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF 220 N N G ++ F++ ++ LQ + + P LL+ F Sbjct: 591 TPNANVLVNRVRGLISQE--------FKEFLLQTLQAETLQGPNINMLLETSSF 636 >SPAC16C9.07 |ppk5|SPAC2G11.01, mug189|serine/threonine protein kinase Ppk5 |Schizosaccharomyces pombe|chr 1|||Manual Length = 836 Score = 41.5 bits (93), Expect = 3e-04 Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 17/134 (12%) Query: 21 IGDVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGN 80 + +++G +L DVI+ N G+ + + + L+ L IH D+K N Sbjct: 596 VTELLGSNLFDVIRE-----NNYKGL-PLIVVKSFALQGLQALRLLQGQNIIHCDLKPEN 649 Query: 81 ILLGED--GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKAD 138 +LL ++L DFG S + +KV +T++ + + APE++ Y + D Sbjct: 650 LLLSHPLKARIKLIDFGSSCFY-------NEKV-YTYLQSRFYRAPEII-LGLEYGKEID 700 Query: 139 IWSFGITAIEMATG 152 IWSFG E+ TG Sbjct: 701 IWSFGCILAELFTG 714 >SPAC2F7.03c |pom1||DYRK family protein kinase Pom1|Schizosaccharomyces pombe|chr 1|||Manual Length = 1087 Score = 41.1 bits (92), Expect = 4e-04 Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 17/132 (12%) Query: 23 DVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNIL 82 +++G +L ++IK SN G+ I ++ +++++ L + IH D+K NIL Sbjct: 779 ELLGKNLYELIK-----SNGFKGL-PIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENIL 832 Query: 83 LGED--GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIW 140 L V++ DFG S + + +T++ + + +PEV+ GY D+W Sbjct: 833 LCHPFKSQVKVIDFGSSCF--------EGECVYTYIQSRFYRSPEVI-LGMGYGTPIDVW 883 Query: 141 SFGITAIEMATG 152 S G EM TG Sbjct: 884 SLGCIIAEMYTG 895 Score = 28.3 bits (60), Expect = 3.2 Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 192 TFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225 +F I DCL+ DP +R T + +H F +D Sbjct: 967 SFLSFISDCLKWDPDERMTPQQAAQHDFLTGKQD 1000 >SPAC23C4.12 |hhp2||serine/threonine protein kinase Hhp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 400 Score = 40.3 bits (90), Expect = 7e-04 Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 12/93 (12%) Query: 9 TIPWSNTEDDYE--IGDVIGGSLLDVIKHKIRVSNCVNG-VFDEATIATVLKEVLKGLEY 65 TI W + Y + D++G SL D+ C G F T+ + +++ +EY Sbjct: 70 TIRWFGVTNSYNAMVMDLLGPSLEDLF--------CYCGRKFTLKTVLLLADQLISRIEY 121 Query: 66 FHSNGQIHRDVKAGNILLGE-DGTVQLADFGVS 97 HS +HRD+K N L+ + V + DFG++ Sbjct: 122 VHSKSFLHRDIKPDNFLMKKHSNVVTMIDFGLA 154 >SPBC21C3.18 |spo4||serine/threonine protein kinase Spo4|Schizosaccharomyces pombe|chr 2|||Manual Length = 429 Score = 37.9 bits (84), Expect = 0.004 Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 52 IATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAW 99 I L+++LKGL + + G IHRD+K GN + DFG++ W Sbjct: 159 IGAYLRDLLKGLAHIDAKGIIHRDIKPGNFAWNPYTQRGVILDFGLAQW 207 Score = 26.6 bits (56), Expect = 9.7 Identities = 12/42 (28%), Positives = 20/42 (47%) Query: 117 GTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHK 158 GT + APEV+ + D+WS G+ + T P+ + Sbjct: 263 GTRGFRAPEVLFRCQNQTSSIDVWSVGVILLCFLTHRYPFFR 304 >SPAC167.01 |ppk4||serine/threonine protein kinase Ppk4 |Schizosaccharomyces pombe|chr 1|||Manual Length = 1072 Score = 37.1 bits (82), Expect = 0.007 Identities = 24/90 (26%), Positives = 46/90 (51%), Gaps = 8/90 (8%) Query: 46 VFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA-----WL 100 +F + ++L ++ G+ + HS +HRD+K NILL + + L+ V A L Sbjct: 745 LFKSIDLVSLLYQIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGL 804 Query: 101 ATGRDMSRQKVRHT---FVGTPCWMAPEVM 127 + D ++ +R+T G+ W +PE++ Sbjct: 805 SKKLDFNQSSLRNTTFEAAGSYGWRSPEIL 834 Score = 28.7 bits (61), Expect = 2.4 Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 196 MIVDCLQKDPTKRPTATELLKHPFF 220 +I D + +P+KRPT +L HP F Sbjct: 914 LIEDMIAFEPSKRPTIEVVLNHPLF 938 >SPBP35G2.05c |cki2||serine/threonine protein kinase Cki2|Schizosaccharomyces pombe|chr 2|||Manual Length = 435 Score = 35.1 bits (77), Expect = 0.028 Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGT-----VQLADFGVSAW 99 F T+A K++L ++ H ++RD+K N L+G + V + DFG++ + Sbjct: 103 FSVKTVAMTAKQMLSRVQTIHEKNLVYRDIKPDNFLIGRPSSRNANMVYMVDFGMAKY 160 >SPCC1322.08 |srk1|mkp1|MAPK-activated protein kinase Srk1|Schizosaccharomyces pombe|chr 3|||Manual Length = 580 Score = 34.3 bits (75), Expect = 0.048 Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 14/142 (9%) Query: 84 GEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFG 143 G G ++LADFG+S + D Q T GT + APE++ +D Y D+W+ G Sbjct: 299 GTIGRIRLADFGLSKVV---WDSHTQ----TPCGTMGYTAPEIV-RDERYSKGVDMWALG 350 Query: 144 ITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQK 203 + G +PP ++L + + + K+ + +I L Sbjct: 351 CVLYTILCG------FPPFYDESISLLTKKVSRGEYSFLSPWWDDISKSAKDLISHLLTV 404 Query: 204 DPTKRPTATELLKHPFFKKAKD 225 DP R + L HP+ +++ Sbjct: 405 DPESRYDIHQFLAHPWISGSRE 426 >SPAC1805.05 |cki3||serine/threonine protein kinase Cki3|Schizosaccharomyces pombe|chr 1|||Manual Length = 439 Score = 33.9 bits (74), Expect = 0.064 Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 5/56 (8%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGT-----VQLADFGVS 97 F T+A + K+++ ++ H I+RD+K N L+G G+ + DFG++ Sbjct: 106 FSPKTVAMIAKQMITRIQSVHERHFIYRDIKPDNFLIGFPGSKTENVIYAVDFGMA 161 >SPBC1347.06c |cki1||serine/threonine protein kinase Cki1|Schizosaccharomyces pombe|chr 2|||Manual Length = 446 Score = 33.1 bits (72), Expect = 0.11 Identities = 15/55 (27%), Positives = 28/55 (50%), Gaps = 5/55 (9%) Query: 47 FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGT-----VQLADFGV 96 F T+A K++L ++ H ++RD+K N L+G + + + DFG+ Sbjct: 103 FSVKTVAMAAKQMLARVQSIHEKSLVYRDIKPDNFLIGRPNSKNANMIYVVDFGM 157 >SPCC1322.12c |bub1||serine/threonine protein kinase Bub1|Schizosaccharomyces pombe|chr 3|||Manual Length = 1044 Score = 32.3 bits (70), Expect = 0.20 Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILL 83 GS+LD++ + + S + DE + E L+ +E H++ IH D+KA N LL Sbjct: 814 GSILDLV-NSMHNSTFSSSGMDEILVVFFSIEFLRIIEALHTHKIIHGDLKADNALL 869 >SPBC1703.05 |||protein kinase, RIO family|Schizosaccharomyces pombe|chr 2|||Manual Length = 336 Score = 31.1 bits (67), Expect = 0.45 Identities = 14/29 (48%), Positives = 17/29 (58%) Query: 66 FHSNGQIHRDVKAGNILLGEDGTVQLADF 94 F NG IH D NI++ EDGT + DF Sbjct: 211 FARNGLIHGDFNEFNIIVREDGTAVVIDF 239 >SPBC119.07 |ppk19||serine/threonine protein kinase Ppk19|Schizosaccharomyces pombe|chr 2|||Manual Length = 1706 Score = 31.1 bits (67), Expect = 0.45 Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 55 VLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADF 94 ++ ++LKG+ H G H D+K+ NIL+ L+DF Sbjct: 126 IMFQLLKGISDCHRLGVCHGDIKSENILITSWNWAYLSDF 165 >SPBC776.12c |hsk1||serine/threonine protein kinase Hsk1|Schizosaccharomyces pombe|chr 2|||Manual Length = 507 Score = 31.1 bits (67), Expect = 0.45 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 93 DFGVSAWLATG--RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMA 150 DF ++ + G ++ +R R GT + APEV+ + K DIWS G+ + Sbjct: 264 DFSIAQETSLGYIKNDTRPSKRANRAGTRGFRAPEVLFKCSSQSPKVDIWSAGVILLSFL 323 Query: 151 TGTAP 155 T P Sbjct: 324 TKRFP 328 >SPCC777.14 |prp4||serine/threonine protein kinase Prp4|Schizosaccharomyces pombe|chr 3|||Manual Length = 477 Score = 28.7 bits (61), Expect = 2.4 Identities = 12/27 (44%), Positives = 16/27 (59%) Query: 196 MIVDCLQKDPTKRPTATELLKHPFFKK 222 ++ CL+ +P KR LKHPFF K Sbjct: 450 LLEKCLELNPEKRVPPEVALKHPFFIK 476 >SPAC926.04c |hsp90|swo1|heat shock protein Hsp90|Schizosaccharomyces pombe|chr 1|||Manual Length = 704 Score = 27.5 bits (58), Expect = 5.6 Identities = 11/38 (28%), Positives = 21/38 (55%) Query: 180 AEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217 AE+K+ +K + F K + + +D RP +LL++ Sbjct: 403 AEDKENFKTFYDAFSKNLKLGIHEDAANRPALAKLLRY 440 >SPBC11C11.07 |rpl1801|rpl18-1, rpl18|60S ribosomal protein L18|Schizosaccharomyces pombe|chr 2|||Manual Length = 187 Score = 27.5 bits (58), Expect = 5.6 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 2/92 (2%) Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102 V V D+ + TV K + L + S R +KAG +L D A G + L Sbjct: 85 VGTVTDDERMLTVPKLSIAALRFTKSARA--RILKAGGEVLTLDQLALRAPTGSNTVLVR 142 Query: 103 GRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYD 134 G+ +R+ RH G AP V + ++ Sbjct: 143 GKKHAREAYRHFGFGPHKHKAPYVRSEGRKFE 174 >SPAPB17E12.13 |rpl1802|rpl18-2|60S ribosomal protein L18|Schizosaccharomyces pombe|chr 1|||Manual Length = 187 Score = 27.1 bits (57), Expect = 7.3 Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 2/92 (2%) Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102 V V D+ + TV K + L + S R +KAG +L D A G + L Sbjct: 85 VGTVTDDERLLTVPKLSVAALRFTKSARA--RILKAGGEVLTLDQLALRAPTGSNTVLLR 142 Query: 103 GRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYD 134 G+ +R+ RH G AP V + ++ Sbjct: 143 GKKHAREAYRHFGFGPHKHKAPYVRSEGRKFE 174 >SPAC222.07c |hri2||eIF2 alpha kinase Hri2|Schizosaccharomyces pombe|chr 1|||Manual Length = 639 Score = 27.1 bits (57), Expect = 7.3 Identities = 11/32 (34%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 55 VLKEVLKGLEYFHSN-GQIHRDVKAGNILLGE 85 + + ++ G+ Y H IHRD+K NI L + Sbjct: 396 LFRMIINGVMYVHEGVNLIHRDIKPSNIFLAK 427 >SPAC17A5.07c |ulp2||SUMO deconjugating cysteine peptidase Ulp2 |Schizosaccharomyces pombe|chr 1|||Manual Length = 652 Score = 26.6 bits (56), Expect = 9.7 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%) Query: 537 PNDSVPISSNLAKLLNGHVAAMQTAPKAITFHLNSSRPNQTYDDK 581 PND++PI S L +L N V + + +S R Q DD+ Sbjct: 44 PNDAIPIKSPLERLANS-VTSPEKPTVRTAIQKDSPRRKQIDDDQ 87 Database: spombe Posted date: Oct 3, 2007 3:31 PM Number of letters in database: 2,362,478 Number of sequences in database: 5004 Lambda K H 0.314 0.130 0.374 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,927,213 Number of Sequences: 5004 Number of extensions: 71282 Number of successful extensions: 397 Number of sequences better than 10.0: 104 Number of HSP's better than 10.0 without gapping: 98 Number of HSP's successfully gapped in prelim test: 6 Number of HSP's that attempted gapping in prelim test: 132 Number of HSP's gapped (non-prelim): 148 length of query: 593 length of database: 2,362,478 effective HSP length: 77 effective length of query: 516 effective length of database: 1,977,170 effective search space: 1020219720 effective search space used: 1020219720 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 42 (22.0 bits) S2: 56 (26.6 bits)
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