Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000560-TA|BGIBMGA000560-PA|IPR000719|Protein kinase,
IPR002290|Serine/threonine protein kinase, IPR011009|Protein
kinase-like
(593 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 355 3e-97
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 355 3e-97
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 355 3e-97
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 355 3e-97
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 347 5e-95
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 346 2e-94
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 338 2e-92
AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-li... 291 6e-78
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 184 6e-46
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 184 6e-46
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 184 6e-46
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 184 6e-46
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 184 6e-46
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 184 6e-46
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 184 6e-46
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 184 6e-46
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 184 6e-46
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 184 6e-46
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 184 6e-46
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 184 6e-46
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 184 6e-46
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 184 6e-46
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 184 6e-46
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 184 6e-46
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 184 6e-46
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 184 6e-46
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 184 6e-46
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 184 6e-46
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 183 2e-45
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 182 3e-45
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 181 7e-45
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 181 7e-45
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 181 7e-45
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 181 7e-45
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 181 7e-45
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 181 7e-45
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 181 7e-45
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 181 7e-45
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 171 4e-42
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 156 2e-37
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 156 2e-37
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 156 2e-37
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 155 4e-37
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 155 4e-37
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 155 4e-37
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 155 4e-37
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 155 4e-37
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 155 4e-37
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 155 4e-37
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 155 4e-37
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 155 4e-37
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 155 4e-37
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 150 2e-35
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 149 2e-35
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 149 2e-35
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 149 4e-35
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 149 4e-35
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 149 4e-35
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 149 4e-35
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 148 5e-35
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 148 5e-35
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 148 5e-35
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 146 2e-34
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 146 3e-34
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 145 3e-34
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 144 6e-34
AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kin... 144 8e-34
AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK... 144 8e-34
AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein. 144 8e-34
AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein. 144 8e-34
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 143 1e-33
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 143 1e-33
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 143 1e-33
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 143 1e-33
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 143 1e-33
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 143 1e-33
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 143 1e-33
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 143 1e-33
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 143 1e-33
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 143 1e-33
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 143 1e-33
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 143 1e-33
BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein. 143 2e-33
BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein. 143 2e-33
AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein. 143 2e-33
AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein. 143 2e-33
AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein. 143 2e-33
AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein. 143 2e-33
AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein. 143 2e-33
AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein. 143 2e-33
BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1... 140 1e-32
AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related ... 140 1e-32
AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-... 140 1e-32
AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related k... 140 1e-32
BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein. 140 1e-32
AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein. 140 1e-32
AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein. 140 1e-32
AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase ... 140 1e-32
AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein. 140 1e-32
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 140 2e-32
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 140 2e-32
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 140 2e-32
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 140 2e-32
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 140 2e-32
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 140 2e-32
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 139 2e-32
BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein. 139 3e-32
U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein. 138 7e-32
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 135 4e-31
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 135 4e-31
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 135 4e-31
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 135 4e-31
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 135 4e-31
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 134 6e-31
U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein. 134 8e-31
BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated prote... 134 8e-31
BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein pr... 133 1e-30
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 132 3e-30
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 132 3e-30
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 132 3e-30
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 132 3e-30
U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor ... 132 3e-30
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 132 3e-30
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 131 6e-30
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 131 6e-30
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 131 6e-30
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 131 6e-30
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 131 6e-30
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 131 6e-30
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 128 4e-29
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 128 4e-29
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 128 4e-29
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 128 4e-29
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 128 4e-29
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 128 4e-29
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 128 4e-29
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 128 4e-29
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 126 3e-28
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 126 3e-28
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 126 3e-28
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 126 3e-28
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 126 3e-28
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 126 3e-28
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 125 5e-28
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 124 1e-27
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 124 1e-27
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 124 1e-27
AF087893-1|AAP97192.1| 295|Homo sapiens DCHT2 protein. 122 4e-27
AF017635-1|AAB70552.1| 267|Homo sapiens DCHT protein. 122 5e-27
BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein. 113 1e-24
BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein. 113 1e-24
AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein. 113 1e-24
AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein. 113 1e-24
U17743-1|AAC50127.1| 399|Homo sapiens JNK activating kinase pro... 108 5e-23
L36870-1|AAC41719.1| 399|Homo sapiens MAP kinase kinase 4 protein. 108 5e-23
DQ015703-1|AAY22176.1| 399|Homo sapiens mitogen-activated prote... 108 5e-23
CR536564-1|CAG38801.1| 399|Homo sapiens MAP2K4 protein. 108 5e-23
BT019676-1|AAV38482.1| 399|Homo sapiens mitogen-activated prote... 108 5e-23
BC036032-1|AAH36032.1| 399|Homo sapiens mitogen-activated prote... 108 5e-23
AF070090-1|AAC24130.1| 399|Homo sapiens mitogen-activated prote... 108 5e-23
AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinas... 108 6e-23
AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinas... 108 6e-23
AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinas... 108 6e-23
AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinas... 108 6e-23
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 107 8e-23
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 107 8e-23
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 107 8e-23
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 107 8e-23
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 107 8e-23
AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protei... 106 2e-22
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 106 3e-22
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 106 3e-22
DQ445915-1|ABE03013.1| 435|Homo sapiens mitogen-activated prote... 106 3e-22
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 106 3e-22
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 106 3e-22
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 106 3e-22
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 106 3e-22
AF022805-1|AAC26142.1| 419|Homo sapiens c-Jun N-terminal kinase... 106 3e-22
AF014401-1|AAB88048.1| 419|Homo sapiens JNK kinase 2 protein. 106 3e-22
AF006689-1|AAB97813.1| 401|Homo sapiens Jnkk2 protein. 106 3e-22
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 105 4e-22
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 105 4e-22
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 105 4e-22
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 105 4e-22
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 105 4e-22
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 105 4e-22
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 105 4e-22
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 105 4e-22
BC060764-1|AAH60764.1| 399|Homo sapiens mitogen-activated prote... 104 8e-22
AF013589-1|AAC16273.1| 462|Homo sapiens mitogen-activated prote... 104 8e-22
AF013588-1|AAC16272.1| 419|Homo sapiens mitogen-activated prote... 104 8e-22
AB102300-1|BAC80799.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102299-1|BAC80798.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102298-1|BAC80797.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102297-1|BAC80796.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102296-1|BAC80795.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102295-1|BAC80794.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102294-1|BAC80793.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102293-1|BAC80792.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102292-1|BAC80791.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102291-1|BAC80790.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102290-1|BAC80789.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102289-1|BAC80788.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102288-1|BAC80787.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102287-1|BAC80786.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102286-1|BAC80785.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102285-1|BAC80784.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102284-1|BAC80783.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102283-1|BAC80782.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102282-1|BAC80781.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
AB102281-1|BAC80780.1| 99|Homo sapiens p21-activated kinase 3 ... 100 1e-20
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 99 5e-20
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 99 5e-20
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 99 5e-20
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 99 5e-20
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 99 5e-20
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 99 5e-20
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 97 1e-19
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 97 1e-19
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 97 1e-19
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 97 1e-19
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 97 1e-19
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 97 1e-19
AK074837-1|BAC11236.1| 231|Homo sapiens protein ( Homo sapiens ... 97 1e-19
AK027589-1|BAB55215.1| 231|Homo sapiens protein ( Homo sapiens ... 97 1e-19
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 97 1e-19
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 97 1e-19
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 97 1e-19
BC038295-1|AAH38295.1| 426|Homo sapiens MAP2K7 protein protein. 97 2e-19
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 97 2e-19
U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein. 97 2e-19
U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein. 97 2e-19
L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein. 97 2e-19
D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b prot... 97 2e-19
CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein. 97 2e-19
CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein. 97 2e-19
BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated prote... 97 2e-19
AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated prote... 97 2e-19
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 97 2e-19
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 97 2e-19
BC034417-1|AAH34417.1| 168|Homo sapiens YSK4 protein protein. 96 3e-19
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 96 3e-19
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 96 3e-19
AC016725-3|AAY14999.1| 168|Homo sapiens unknown protein. 96 3e-19
BC065755-1|AAH65755.1| 234|Homo sapiens MAP3K2 protein protein. 95 5e-19
AY290821-1|AAP42280.1| 348|Homo sapiens LYK5 protein protein. 95 6e-19
AK075005-1|BAC11349.1| 348|Homo sapiens protein ( Homo sapiens ... 95 6e-19
AK074771-1|BAC11197.1| 394|Homo sapiens protein ( Homo sapiens ... 95 6e-19
AF308302-1|AAG48269.1| 431|Homo sapiens serologically defined b... 95 6e-19
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 95 6e-19
AK026727-1|BAB15538.1| 168|Homo sapiens protein ( Homo sapiens ... 95 8e-19
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 93 3e-18
X96757-1|CAA65532.1| 334|Homo sapiens MAP kinase kinase protein. 93 3e-18
U49732-1|AAB05035.1| 334|Homo sapiens MAP kinase kinase MEK6 pr... 93 3e-18
U39657-1|AAC50389.1| 334|Homo sapiens MAP kinase kinase 6 protein. 93 3e-18
U39656-1|AAC50388.1| 334|Homo sapiens MAP kinase kinase 6 protein. 93 3e-18
U39065-1|AAB03705.1| 334|Homo sapiens MAP kinase kinase 6b prot... 93 3e-18
U39064-1|AAB03708.1| 278|Homo sapiens MAP kinase kinase 6 protein. 93 3e-18
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 93 3e-18
D87905-1|BAA13496.1| 334|Homo sapiens mitogen-activated protein... 93 3e-18
BC012009-1|AAH12009.1| 334|Homo sapiens mitogen-activated prote... 93 3e-18
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 93 3e-18
Z25426-1|CAA80913.1| 113|Homo sapiens protein-serine/threonine ... 92 4e-18
U71088-1|AAB16852.2| 444|Homo sapiens MAP kinase kinase MEK5c p... 92 4e-18
U25265-1|AAA96146.1| 438|Homo sapiens MEK5 protein. 92 4e-18
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 91 8e-18
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 91 8e-18
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 91 8e-18
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 91 8e-18
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 91 8e-18
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 91 8e-18
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 91 1e-17
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 91 1e-17
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 90 2e-17
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 90 2e-17
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 90 2e-17
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 90 2e-17
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 90 2e-17
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 90 2e-17
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 90 2e-17
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 90 2e-17
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 90 2e-17
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 90 2e-17
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 90 2e-17
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 89 3e-17
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 89 3e-17
Z25422-1|CAA80909.1| 108|Homo sapiens protein-serine/threonine ... 89 4e-17
BC043641-1|AAH43641.1| 234|Homo sapiens LYK5 protein protein. 89 4e-17
AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase, g... 89 4e-17
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 88 7e-17
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 88 7e-17
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 88 7e-17
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 88 7e-17
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 88 9e-17
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 87 2e-16
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 87 2e-16
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 87 2e-16
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 87 2e-16
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 87 2e-16
AK024376-1|BAB14901.1| 398|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 87 2e-16
Z25430-1|CAA80917.1| 101|Homo sapiens protein-serine/threonine ... 86 3e-16
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 86 3e-16
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 86 3e-16
BC090871-1|AAH90871.1| 377|Homo sapiens ALS2CR2 protein protein. 86 3e-16
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 86 3e-16
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 86 3e-16
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 86 3e-16
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 86 3e-16
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 86 3e-16
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 86 3e-16
BC008302-1|AAH08302.1| 418|Homo sapiens amyotrophic lateral scl... 86 3e-16
AY093697-1|AAM19143.1| 418|Homo sapiens ILP-interacting protein... 86 3e-16
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 86 3e-16
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 86 3e-16
AK027637-1|BAB55254.1| 418|Homo sapiens protein ( Homo sapiens ... 86 3e-16
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 86 3e-16
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 86 3e-16
AC007282-3|AAY14692.1| 418|Homo sapiens unknown protein. 86 3e-16
AB038950-1|BAB32500.1| 418|Homo sapiens amyotrophic lateral scl... 86 3e-16
Z14138-1|CAA78512.1| 467|Homo sapiens protein ( H.sapiens (Ewin... 86 4e-16
CR542284-1|CAG47079.1| 467|Homo sapiens MAP3K8 protein. 86 4e-16
BC113566-1|AAI13567.1| 467|Homo sapiens mitogen-activated prote... 86 4e-16
BC104833-1|AAI04834.1| 467|Homo sapiens mitogen-activated prote... 86 4e-16
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 86 4e-16
AY309013-1|AAP45053.1| 467|Homo sapiens mitogen-activated prote... 86 4e-16
AL161651-12|CAI14227.1| 467|Homo sapiens mitogen-activated prot... 86 4e-16
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 86 4e-16
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 86 4e-16
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 85 5e-16
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 85 5e-16
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 85 5e-16
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 85 5e-16
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 85 5e-16
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 85 5e-16
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 85 5e-16
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 85 5e-16
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 85 5e-16
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 85 5e-16
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 85 5e-16
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 85 5e-16
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 85 5e-16
AL137249-6|CAI39456.1| 209|Homo sapiens serine/threonine kinase... 85 5e-16
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 85 5e-16
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 85 5e-16
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 85 5e-16
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 85 5e-16
D14497-1|BAA03387.1| 467|Homo sapiens proto-oncogene protein pr... 85 7e-16
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 85 7e-16
AL358612-2|CAH73815.1| 197|Homo sapiens myosin IIIA protein. 85 9e-16
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 84 2e-15
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 84 2e-15
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 84 2e-15
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 82 5e-15
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 82 5e-15
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 82 5e-15
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 82 5e-15
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 82 5e-15
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 82 5e-15
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 82 5e-15
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 82 5e-15
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 82 5e-15
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 82 5e-15
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 82 5e-15
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 82 5e-15
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 82 5e-15
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 82 6e-15
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 82 6e-15
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 82 6e-15
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 82 6e-15
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 82 6e-15
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 82 6e-15
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 81 8e-15
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 81 8e-15
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 81 8e-15
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 81 8e-15
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 81 8e-15
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 81 8e-15
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 81 8e-15
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 81 8e-15
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 81 8e-15
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 81 8e-15
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 81 8e-15
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 81 8e-15
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 81 8e-15
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 81 8e-15
U63973-1|AAB05929.1| 563|Homo sapiens rhodopsin kinase protein. 81 1e-14
L77503-1|AAG50439.1| 563|Homo sapiens rhodopsin kinase protein. 81 1e-14
L77502-1|AAT00534.2| 563|Homo sapiens rhodopsin kinase protein. 81 1e-14
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 81 1e-14
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 81 1e-14
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 81 1e-14
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 81 1e-14
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 81 1e-14
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 81 1e-14
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 81 1e-14
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 81 1e-14
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 81 1e-14
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 81 1e-14
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 81 1e-14
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 81 1e-14
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 81 1e-14
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 81 1e-14
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 81 1e-14
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 81 1e-14
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 81 1e-14
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 81 1e-14
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 81 1e-14
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 81 1e-14
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 81 1e-14
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 81 1e-14
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 81 1e-14
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 81 1e-14
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 81 1e-14
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 81 1e-14
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 81 1e-14
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 81 1e-14
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 81 1e-14
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 81 1e-14
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 81 1e-14
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 81 1e-14
AK027345-1|BAB55050.1| 142|Homo sapiens protein ( Homo sapiens ... 80 2e-14
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 80 3e-14
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 80 3e-14
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 80 3e-14
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 80 3e-14
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 79 3e-14
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 79 3e-14
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 79 3e-14
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 79 3e-14
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 79 3e-14
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 79 3e-14
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 79 3e-14
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 79 3e-14
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 79 3e-14
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 79 3e-14
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 79 3e-14
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 79 3e-14
L05624-1|AAA36318.1| 393|Homo sapiens MAP kinase kinase protein. 79 4e-14
BC139729-1|AAI39730.1| 393|Homo sapiens mitogen-activated prote... 79 4e-14
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 79 4e-14
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 79 4e-14
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 79 4e-14
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 79 4e-14
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 79 4e-14
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 79 4e-14
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 79 4e-14
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 79 4e-14
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 79 6e-14
AY227114-1|AAO37094.1| 256|Homo sapiens kinase/transmembrane do... 79 6e-14
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 79 6e-14
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 78 8e-14
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 78 8e-14
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 78 8e-14
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 78 8e-14
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 78 8e-14
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 78 8e-14
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 78 8e-14
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 78 8e-14
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 78 8e-14
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 78 8e-14
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 78 8e-14
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 78 8e-14
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 78 8e-14
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 355 bits (873), Expect = 3e-97
Identities = 163/239 (68%), Positives = 197/239 (82%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IKH + +GV DE+TIAT+L+EVL+GLEY H NGQIHRDVKAGNILLGE
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGE 156
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKADIWSFGIT
Sbjct: 157 DGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGIT 216
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP+L+TG ++K+ K YGK+FRKMI CLQKDP
Sbjct: 217 AIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KRPTA ELL+H FF+KAK++++L + + P++ R K ++ +SGRLH+T G
Sbjct: 277 EKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKV-RRVPGSSGRLHKTEDG 334
Score = 79.4 bits (187), Expect = 3e-14
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NS+ ELNDIRFE+ G+DTAEG++ EL+ AGL+D D V +++NL K++
Sbjct: 437 VLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVE----- 491
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
+ +++TF L S + DD LIGFAQ++I
Sbjct: 492 EPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSI 526
Score = 32.7 bits (71), Expect = 3.8
Identities = 12/31 (38%), Positives = 20/31 (64%)
Query: 4 STNTNTIPWSNTEDDYEIGDVIGGSLLDVIK 34
S +++ +PWS DDYE+ +VIG V++
Sbjct: 2 SEDSSALPWSINRDDYELQEVIGSGATAVVQ 32
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 355 bits (873), Expect = 3e-97
Identities = 163/239 (68%), Positives = 197/239 (82%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IKH + +GV DE+TIAT+L+EVL+GLEY H NGQIHRDVKAGNILLGE
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGE 156
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKADIWSFGIT
Sbjct: 157 DGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGIT 216
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP+L+TG ++K+ K YGK+FRKMI CLQKDP
Sbjct: 217 AIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KRPTA ELL+H FF+KAK++++L + + P++ R K ++ +SGRLH+T G
Sbjct: 277 EKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKV-RRVPGSSGRLHKTEDG 334
Score = 79.4 bits (187), Expect = 3e-14
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NS+ ELNDIRFE+ G+DTAEG++ EL+ AGL+D D V +++NL K++
Sbjct: 437 VLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVE----- 491
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
+ +++TF L S + DD LIGFAQ++I
Sbjct: 492 EPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSI 526
Score = 32.7 bits (71), Expect = 3.8
Identities = 12/31 (38%), Positives = 20/31 (64%)
Query: 4 STNTNTIPWSNTEDDYEIGDVIGGSLLDVIK 34
S +++ +PWS DDYE+ +VIG V++
Sbjct: 2 SEDSSALPWSINRDDYELQEVIGSGATAVVQ 32
>AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein.
Length = 467
Score = 355 bits (873), Expect = 3e-97
Identities = 163/239 (68%), Positives = 197/239 (82%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IKH + +GV DE+TIAT+L+EVL+GLEY H NGQIHRDVKAGNILLGE
Sbjct: 37 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGE 96
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKADIWSFGIT
Sbjct: 97 DGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGIT 156
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP+L+TG ++K+ K YGK+FRKMI CLQKDP
Sbjct: 157 AIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 216
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KRPTA ELL+H FF+KAK++++L + + P++ R K ++ +SGRLH+T G
Sbjct: 217 EKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKV-RRVPGSSGRLHKTEDG 274
Score = 79.4 bits (187), Expect = 3e-14
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NS+ ELNDIRFE+ G+DTAEG++ EL+ AGL+D D V +++NL K++
Sbjct: 377 VLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVE----- 431
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
+ +++TF L S + DD LIGFAQ++I
Sbjct: 432 EPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSI 466
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 355 bits (873), Expect = 3e-97
Identities = 163/239 (68%), Positives = 197/239 (82%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IKH + +GV DE+TIAT+L+EVL+GLEY H NGQIHRDVKAGNILLGE
Sbjct: 97 GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGE 156
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKADIWSFGIT
Sbjct: 157 DGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGIT 216
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP+L+TG ++K+ K YGK+FRKMI CLQKDP
Sbjct: 217 AIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDP 276
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KRPTA ELL+H FF+KAK++++L + + P++ R K ++ +SGRLH+T G
Sbjct: 277 EKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKV-RRVPGSSGRLHKTEDG 334
Score = 79.4 bits (187), Expect = 3e-14
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NS+ ELNDIRFE+ G+DTAEG++ EL+ AGL+D D V +++NL K++
Sbjct: 437 VLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVE----- 491
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
+ +++TF L S + DD LIGFAQ++I
Sbjct: 492 EPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSI 526
Score = 32.7 bits (71), Expect = 3.8
Identities = 12/31 (38%), Positives = 20/31 (64%)
Query: 4 STNTNTIPWSNTEDDYEIGDVIGGSLLDVIK 34
S +++ +PWS DDYE+ +VIG V++
Sbjct: 2 SEDSSALPWSINRDDYELQEVIGSGATAVVQ 32
>AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase SPAK
protein.
Length = 547
Score = 347 bits (854), Expect = 5e-95
Identities = 161/239 (67%), Positives = 194/239 (81%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IK+ + NGV +EA IAT+LKEVL+GL+Y H NGQIHRD+KAGNILLGE
Sbjct: 145 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 204
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKAD+WSFGIT
Sbjct: 205 DGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT 264
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP L+TG E+K+ K YGK+FRK++ CLQKDP
Sbjct: 265 AIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDP 324
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
+KRPTA ELLK FF+KAK+R+YL + L+ P + R K ++ +SG LH+T G
Sbjct: 325 SKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKV-RRVPGSSGHLHKTEDG 382
Score = 78.2 bits (184), Expect = 8e-14
Identities = 42/95 (44%), Positives = 65/95 (68%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NSR ELNDIRFE+ G+DTA+G++ EL AGL+D +D V +++NL K+++
Sbjct: 457 VLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDD---- 512
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
A K +TF L S ++ D+ LIGFAQ+++
Sbjct: 513 -PKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSV 546
>AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kinase
protein.
Length = 547
Score = 346 bits (850), Expect = 2e-94
Identities = 160/239 (66%), Positives = 193/239 (80%), Gaps = 1/239 (0%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IK+ + NGV +EA IAT+ KEVL+GL+Y H NGQIHRD+KAGNILLGE
Sbjct: 145 GGSMLDIIKYIVNRGEHKNGVLEEAIIATIFKEVLEGLDYLHRNGQIHRDLKAGNILLGE 204
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKAD+WSFGIT
Sbjct: 205 DGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT 264
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP L+TG E+K+ K YGK+FRK++ CLQKDP
Sbjct: 265 AIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDP 324
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
+KRPTA ELLK FF+KAK+R+YL + L+ P + R K ++ +SG LH+T G
Sbjct: 325 SKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKV-RRVPGSSGHLHKTEDG 382
Score = 78.2 bits (184), Expect = 8e-14
Identities = 42/95 (44%), Positives = 65/95 (68%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NSR ELNDIRFE+ G+DTA+G++ EL AGL+D +D V +++NL K+++
Sbjct: 457 VLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDD---- 512
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
A K +TF L S ++ D+ LIGFAQ+++
Sbjct: 513 -PKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSV 546
>AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein.
Length = 363
Score = 338 bits (832), Expect = 2e-92
Identities = 155/221 (70%), Positives = 184/221 (83%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IK+ + NGV +EA IAT+LKEVL+GL+Y H NGQIHRD+KAGNILLGE
Sbjct: 143 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 202
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVMEQ GYDFKAD+WSFGIT
Sbjct: 203 DGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGIT 262
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+ATG APYHKYPPMKVLMLTLQNDPP L+TG E+K+ K YGK+FRK++ CLQKDP
Sbjct: 263 AIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDP 322
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTK 246
+KRPTA ELLK FF+KAK+R+YL + L+ P + R K
Sbjct: 323 SKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKK 363
>AY629298-1|AAT65492.1| 476|Homo sapiens small intestine SPAK-like
kinase protein.
Length = 476
Score = 291 bits (713), Expect = 6e-78
Identities = 144/239 (60%), Positives = 176/239 (73%), Gaps = 21/239 (8%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+LD+IK+ + NGV +EA IAT+LKEVL+GL+Y H NGQIHRD+KAGNILLGE
Sbjct: 94 GGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGE 153
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG+VQ+ADFGVSA+LATG D++R KVR TFVGTPCWMAPEVM
Sbjct: 154 DGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVM------------------ 195
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
E+ATG APYHKYPPMKVLMLTLQNDPP L+TG E+K+ K YGK+FRK++ CLQKDP
Sbjct: 196 --ELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDP 253
Query: 206 TKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
+KRPTA ELLK FF+KAK+R+YL + L+ P + R K ++ +SG LH+T G
Sbjct: 254 SKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKV-RRVPGSSGHLHKTEDG 311
Score = 78.2 bits (184), Expect = 8e-14
Identities = 42/95 (44%), Positives = 65/95 (68%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NSR ELNDIRFE+ G+DTA+G++ EL AGL+D +D V +++NL K+++
Sbjct: 386 VLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDD---- 441
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
A K +TF L S ++ D+ LIGFAQ+++
Sbjct: 442 -PKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSV 475
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 126 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 180
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 181 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 239
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 240 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 290
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 291 KKTSYLTELI 300
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 31 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 85
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 86 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 144
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 145 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 195
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 196 KKTSYLTELI 205
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 126 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 180
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 181 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 239
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 240 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 290
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 291 KKTSYLTELI 300
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 31 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 85
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 86 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 144
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 145 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 195
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 196 KKTSYLTELI 205
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 27 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 77
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 78 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 131
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 132 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 182
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 183 SFRPTAKELLKHKFIVKNSKKTSYLTELI 211
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 126 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 180
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 181 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 239
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 240 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 290
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 291 KKTSYLTELI 300
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 184 bits (449), Expect = 6e-46
Identities = 97/190 (51%), Positives = 124/190 (65%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 184 bits (449), Expect = 6e-46
Identities = 105/209 (50%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + K+F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTKSFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 183 bits (445), Expect = 2e-45
Identities = 104/209 (49%), Positives = 132/209 (63%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD KADIWS GIT
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSKADIWSLGIT 208
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N+PP L + ++F++ I CL KDP
Sbjct: 209 AIELAKGEPPNSDMHPMRVLFLIPKNNPPTL---------VGDFTESFKEFIDACLNKDP 259
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ RPTA ELLKH F K +K YLT+ +
Sbjct: 260 SFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 182 bits (443), Expect = 3e-45
Identities = 96/190 (50%), Positives = 123/190 (64%), Gaps = 16/190 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G DE IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E G V+LAD GV+ G+
Sbjct: 114 GPLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADIGVA-----GQ 168
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
Q R+TFVGTP WMAPEV++Q YD KADIWS GITAIE+A G P+ + PMKV
Sbjct: 169 LTDTQIKRNTFVGTPFWMAPEVIKQS-AYDSKADIWSLGITAIELARGEPPHSELHPMKV 227
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF-FKKA 223
L L +N+PP L+ Y K ++ + CL K+P+ RPTA ELLKH F + A
Sbjct: 228 LFLIPKNNPPTLEGN---------YSKPLKEFVEACLNKEPSFRPTAKELLKHKFILRNA 278
Query: 224 KDRKYLTQTL 233
K YLT+ +
Sbjct: 279 KKTSYLTELI 288
>X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase 25
(STE20 homolog, yeast) protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein.
Length = 426
Score = 181 bits (440), Expect = 7e-45
Identities = 101/209 (48%), Positives = 129/209 (61%), Gaps = 25/209 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD++K G +E IAT+L+E+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 100 GGSALDLLKP---------GPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSE 150
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YDFKADIWS GIT
Sbjct: 151 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIKQS-AYDFKADIWSLGIT 204
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
AIE+A G P PM+VL L +N PP L+ + K F++ + CL KDP
Sbjct: 205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLE---------GQHSKPFKEFVEACLNKDP 255
Query: 206 TKRPTATELLKHPFFKK-AKDRKYLTQTL 233
RPTA ELLKH F + K +LT+ +
Sbjct: 256 RFRPTAKELLKHKFITRYTKKTSFLTELI 284
>AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ20549 fis, clone KAT11561. ).
Length = 293
Score = 171 bits (417), Expect = 4e-42
Identities = 93/180 (51%), Positives = 117/180 (65%), Gaps = 16/180 (8%)
Query: 55 VLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHT 114
+LKE+LKGL+Y HS +IHRD+KA N+LL E G V+LADFGV+ G+ Q R+T
Sbjct: 1 MLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVA-----GQLTDTQIKRNT 55
Query: 115 FVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPP 174
FVGTP WMAPEV++Q YD KADIWS GITAIE+A G P PM+VL L +N+PP
Sbjct: 56 FVGTPFWMAPEVIQQS-AYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPP 114
Query: 175 NLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF-KKAKDRKYLTQTL 233
L + K+F++ I CL KDP+ RPTA ELLKH F K +K YLT+ +
Sbjct: 115 TL---------VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 165
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 156 bits (378), Expect = 2e-37
Identities = 85/181 (46%), Positives = 110/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+LK LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 115 NKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 173
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GIT+IEMA G PY PM+
Sbjct: 174 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMR 228
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K+P +R TAT+LL+HPF K A
Sbjct: 229 AIFMIPTNPPPTF-------RKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNA 281
Query: 224 K 224
K
Sbjct: 282 K 282
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 156 bits (378), Expect = 2e-37
Identities = 85/181 (46%), Positives = 110/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+LK LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 115 NKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 173
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GIT+IEMA G PY PM+
Sbjct: 174 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMR 228
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K+P +R TAT+LL+HPF K A
Sbjct: 229 AIFMIPTNPPPTF-------RKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNA 281
Query: 224 K 224
K
Sbjct: 282 K 282
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 156 bits (378), Expect = 2e-37
Identities = 85/181 (46%), Positives = 110/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+LK LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 115 NKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 173
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GIT+IEMA G PY PM+
Sbjct: 174 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMR 228
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K+P +R TAT+LL+HPF K A
Sbjct: 229 AIFMIPTNPPPTF-------RKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNA 281
Query: 224 K 224
K
Sbjct: 282 K 282
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKRPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 155 bits (376), Expect = 4e-37
Identities = 84/181 (46%), Positives = 109/181 (60%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 142 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 200
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP WMAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 201 -TMAK---RNTVIGTPFWMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 255
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 256 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 308
Query: 224 K 224
K
Sbjct: 309 K 309
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 150 bits (363), Expect = 2e-35
Identities = 83/181 (45%), Positives = 108/181 (59%), Gaps = 13/181 (7%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATG 103
N E IAT+L+ LKGLEY H +IHRD+KAGNILL +G +LADFGV+ L
Sbjct: 118 NKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTD- 176
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
M++ R+T +GTP MAPEV+ Q+ GY+ ADIWS GITAIEMA G PY PM+
Sbjct: 177 -TMAK---RNTVIGTPFLMAPEVI-QEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMR 231
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + N PP + + + F + CL K P +R TAT+LL+HPF + A
Sbjct: 232 AIFMIPTNPPPTF-------RKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSA 284
Query: 224 K 224
K
Sbjct: 285 K 285
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 149 bits (362), Expect = 2e-35
Identities = 97/237 (40%), Positives = 126/237 (53%), Gaps = 29/237 (12%)
Query: 14 NTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEY 65
N D Y +GD + GGSL DV+ + C+ DEA IA V +E L+ LE+
Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVVTE----TACM----DEAQIAAVCRECLQALEF 359
Query: 66 FHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPE 125
H+N IHRD+K+ N+LLG +G+V+L DFG A + Q R T VGTP WMAPE
Sbjct: 360 LHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQIT-----PEQSKRSTMVGTPYWMAPE 414
Query: 126 VMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQ 185
V+ + Y K DIWS GI AIEM G PY P++ L L N P L EK
Sbjct: 415 VVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN--PEK-- 469
Query: 186 YKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMET 242
FR + CL+ D KR +A ELL+HPF K AK LT ++A +M++
Sbjct: 470 ---LSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKS 523
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 149 bits (362), Expect = 2e-35
Identities = 97/237 (40%), Positives = 125/237 (52%), Gaps = 30/237 (12%)
Query: 14 NTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEY 65
N D Y +GD + GGSL DV+ C+ DEA IA V +E L+ LE+
Sbjct: 308 NFLDSYLVGDELFVVMEYLAGGSLTDVV-----TETCM----DEAQIAAVCRECLQALEF 358
Query: 66 FHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPE 125
H+N IHRD+K+ N+LLG +G+V+L DFG A + Q R T VGTP WMAPE
Sbjct: 359 LHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQIT-----PEQSKRSTMVGTPYWMAPE 413
Query: 126 VMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQ 185
V+ + Y K DIWS GI AIEM G PY P++ L L N P L EK
Sbjct: 414 VVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN--PEK-- 468
Query: 186 YKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMET 242
FR + CL+ D KR +A ELL+HPF K AK LT ++A +M++
Sbjct: 469 ---LSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKS 522
>AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 317 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 364
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 365 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 419
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 420 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 479 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 531
Query: 233 LVA 235
++A
Sbjct: 532 IIA 534
>AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 332 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 379
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 380 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 434
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 435 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 493
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 494 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 546
Query: 233 LVA 235
++A
Sbjct: 547 IIA 549
>AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 332 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 379
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 380 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 434
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 435 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 493
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 494 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 546
Query: 233 LVA 235
++A
Sbjct: 547 IIA 549
>AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 317 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 364
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 365 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 419
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 420 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 479 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 531
Query: 233 LVA 235
++A
Sbjct: 532 IIA 534
>AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 317 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 364
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 365 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 419
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 420 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 479 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 531
Query: 233 LVA 235
++A
Sbjct: 532 IIA 534
>AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 332 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 379
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 380 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 434
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 435 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 493
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 494 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 546
Query: 233 LVA 235
++A
Sbjct: 547 IIA 549
>AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3
protein.
Length = 544
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 317 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 364
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 365 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 419
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 420 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 479 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 531
Query: 233 LVA 235
++A
Sbjct: 532 IIA 534
>AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3
protein.
Length = 544
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 317 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 364
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 365 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 419
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 420 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 479 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 531
Query: 233 LVA 235
++A
Sbjct: 532 IIA 534
>AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3
protein.
Length = 559
Score = 149 bits (360), Expect = 4e-35
Identities = 98/243 (40%), Positives = 127/243 (52%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 332 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 379
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 380 AAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 434
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 435 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 493
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L + ++ A FR + CL+ D +R +A ELL+HPF K AK LT
Sbjct: 494 TPEL----QNPERLSA---VFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPL 546
Query: 233 LVA 235
++A
Sbjct: 547 IIA 549
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 148 bits (359), Expect = 5e-35
Identities = 90/229 (39%), Positives = 121/229 (52%), Gaps = 14/229 (6%)
Query: 14 NTEDDYEIGDVIGGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIH 73
N D Y +GD + +++ + + DEA IA V +E L+ LE+ H+N IH
Sbjct: 277 NFLDSYLVGDELF-VVMEYLAGRSLTDVVTETCMDEAQIAAVCRECLQALEFLHANQVIH 335
Query: 74 RDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGY 133
RD+K+ N+LLG +G+V+L DFG A + Q R T VGTP WMAPEV+ + Y
Sbjct: 336 RDIKSDNVLLGMEGSVKLTDFGFCAQIT-----PEQSKRSTMVGTPYWMAPEVVTR-KAY 389
Query: 134 DFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTF 193
K DIWS GI AIEM G PY P++ L L N P L EK F
Sbjct: 390 GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQN--PEK-----LSPIF 442
Query: 194 RKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMET 242
R + CL+ D KR +A ELL+HPF K AK LT ++A +M++
Sbjct: 443 RDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKS 491
>AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 8 protein.
Length = 1268
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 7 protein.
Length = 1297
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 6 protein.
Length = 1323
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 5 protein.
Length = 1276
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 4 protein.
Length = 1352
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 3 protein.
Length = 1305
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 2 protein.
Length = 1331
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacting
kinase, splice variant 1 protein.
Length = 1360
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 272 KNHSQRPATEQLMKHPFIR 290
>AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein.
Length = 1385
Score = 148 bits (359), Expect = 5e-35
Identities = 85/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D+IK N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 136 GSVTDLIK------NTKGNTLKEEWIAYICREILRGLSHLHQHKVIHRDIKGQNVLLTEN 189
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YDFK+D+WS
Sbjct: 190 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDFKSDLWSL 244
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N P L + K + K F+ I CL
Sbjct: 245 GITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKS--------KKWSKKFQSFIESCLV 296
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ ++RP +L+KHPF +
Sbjct: 297 KNHSQRPATEQLMKHPFIR 315
>AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein.
Length = 968
Score = 146 bits (354), Expect = 2e-34
Identities = 81/191 (42%), Positives = 116/191 (60%), Gaps = 17/191 (8%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E I V +++L+ L + HS IHRD+KAGN+L+ +G ++LADFGVSA +++
Sbjct: 131 EPQIQVVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA-----KNLKT 185
Query: 109 QKVRHTFVGTPCWMAPEVME----QDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
+ R +F+GTP WMAPEV+ +D YD+KADIWS GIT IEMA P+H+ PM+V
Sbjct: 186 LQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRV 245
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAK 224
L+ ++DPP L T ++ + FR + L K+P RP+A +LL+HPF
Sbjct: 246 LLKIAKSDPPTLLTPSK-------WSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSIT 298
Query: 225 DRKYLTQTLVA 235
K L + LVA
Sbjct: 299 SNKALRE-LVA 308
>BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase 10
protein.
Length = 968
Score = 146 bits (353), Expect = 3e-34
Identities = 81/191 (42%), Positives = 116/191 (60%), Gaps = 17/191 (8%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E I V +++L+ L + HS IHRD+KAGN+L+ +G ++LADFGVSA +++
Sbjct: 131 EPQIQEVCRQMLEALNFLHSKRIIHRDLKAGNVLMTLEGDIRLADFGVSA-----KNLKT 185
Query: 109 QKVRHTFVGTPCWMAPEVME----QDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
+ R +F+GTP WMAPEV+ +D YD+KADIWS GIT IEMA P+H+ PM+V
Sbjct: 186 LQKRDSFIGTPYWMAPEVVMCETMKDTPYDYKADIWSLGITLIEMAQIEPPHHELNPMRV 245
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAK 224
L+ ++DPP L T ++ + FR + L K+P RP+A +LL+HPF
Sbjct: 246 LLKIAKSDPPTLLTPSK-------WSVEFRDFLKIALDKNPETRPSAAQLLEHPFVSSIT 298
Query: 225 DRKYLTQTLVA 235
K L + LVA
Sbjct: 299 SNKALRE-LVA 308
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 145 bits (352), Expect = 3e-34
Identities = 100/243 (41%), Positives = 123/243 (50%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 319 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 366
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ LE+ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 367 AAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 421
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 422 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG 480
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L EK FR + CL+ D KR +A ELL+H F K AK LT
Sbjct: 481 TPELQN--PEK-----LSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPL 533
Query: 233 LVA 235
+ A
Sbjct: 534 IAA 536
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 144 bits (350), Expect = 6e-34
Identities = 100/243 (41%), Positives = 122/243 (50%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 319 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 366
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ LE+ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 367 AAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 421
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 422 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG 480
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L EK FR + CL D KR +A ELL+H F K AK LT
Sbjct: 481 TPELQN--PEK-----LSAIFRDFLNRCLDMDVEKRGSAKELLQHQFLKIAKPLSSLTPL 533
Query: 233 LVA 235
+ A
Sbjct: 534 IAA 536
>AY212247-1|AAO32626.1| 1239|Homo sapiens Ste20 group protein kinase
HGK protein.
Length = 1239
Score = 144 bits (349), Expect = 8e-34
Identities = 84/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D++K N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YD+++D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSC 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N PP L + K + K F I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFFSFIEGCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ +RP+ +LLKHPF +
Sbjct: 272 KNYMQRPSTEQLLKHPFIR 290
>AF096300-1|AAD16137.1| 1165|Homo sapiens HPK/GCK-like kinase HGK
protein.
Length = 1165
Score = 144 bits (349), Expect = 8e-34
Identities = 84/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D++K N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 111 GSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTEN 164
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YD+++D+WS
Sbjct: 165 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSC 219
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N PP L + K + K F I CL
Sbjct: 220 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFFSFIEGCLV 271
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ +RP+ +LLKHPF +
Sbjct: 272 KNYMQRPSTEQLLKHPFIR 290
>AC005035-1|AAY14969.1| 1260|Homo sapiens unknown protein.
Length = 1260
Score = 144 bits (349), Expect = 8e-34
Identities = 84/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D++K N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 51 GSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTEN 104
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YD+++D+WS
Sbjct: 105 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSC 159
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N PP L + K + K F I CL
Sbjct: 160 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFFSFIEGCLV 211
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ +RP+ +LLKHPF +
Sbjct: 212 KNYMQRPSTEQLLKHPFIR 230
>AB014587-1|BAA31662.1| 1175|Homo sapiens KIAA0687 protein protein.
Length = 1175
Score = 144 bits (349), Expect = 8e-34
Identities = 84/199 (42%), Positives = 114/199 (57%), Gaps = 23/199 (11%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ D++K N E IA + +E+L+GL + H + IHRD+K N+LL E+
Sbjct: 74 GSITDLVK------NTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTEN 127
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSF 142
V+L DFGVSA L R + R R+TF+GTP WMAPEV+ D YD+++D+WS
Sbjct: 128 AEVKLVDFGVSAQL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSC 182
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P PM+ L L +N PP L + K + K F I CL
Sbjct: 183 GITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFFSFIEGCLV 234
Query: 203 KDPTKRPTATELLKHPFFK 221
K+ +RP+ +LLKHPF +
Sbjct: 235 KNYMQRPSTEQLLKHPFIR 253
>U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein.
Length = 545
Score = 143 bits (347), Expect = 1e-33
Identities = 100/243 (41%), Positives = 122/243 (50%), Gaps = 33/243 (13%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 319 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 366
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ LE HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 367 AAVCRECLQALESLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 421
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 422 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG 480
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDRKYLTQT 232
P L EK FR + CL+ D KR +A ELL+H F K AK LT
Sbjct: 481 TPELQN--PEK-----LSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPL 533
Query: 233 LVA 235
+ A
Sbjct: 534 IAA 536
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 141 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 198
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 199 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 255
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 256 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 303
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 143 bits (347), Expect = 1e-33
Identities = 78/175 (44%), Positives = 105/175 (60%), Gaps = 16/175 (9%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E+ I V K+ L L Y H N IHRD+KAGNIL DG ++LADFGVSA R + R
Sbjct: 129 ESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSA--KNTRTIQR 186
Query: 109 QKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKV 164
R +F+GTP WMAPEV+ +D YD+KAD+WS GIT IEMA P+H+ PM+V
Sbjct: 187 ---RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRV 243
Query: 165 LMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
L+ +++PP L Q + F+ + CL+K+ R T ++LL+HPF
Sbjct: 244 LLKIAKSEPPTL-------AQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPF 291
>BC125272-1|AAI25273.1| 625|Homo sapiens MYO3A protein protein.
Length = 625
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>BC119811-1|AAI19812.1| 664|Homo sapiens MYO3A protein protein.
Length = 664
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AY101367-1|AAM34500.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AL391812-1|CAI17380.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AL360217-1|CAD13206.2| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AL358612-1|CAH73814.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AL162503-4|CAH73661.1| 1616|Homo sapiens myosin IIIA protein.
Length = 1616
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>AF229172-1|AAF70861.1| 1615|Homo sapiens class III myosin protein.
Length = 1615
Score = 143 bits (346), Expect = 2e-33
Identities = 88/210 (41%), Positives = 116/210 (55%), Gaps = 20/210 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P PM+ L +N PP L Q + + F I CL
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRNPPPKL-------RQPELWSAEFNDFISKCL 268
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQ 231
KD KRPT +ELL+H F + + + + Q
Sbjct: 269 TKDYEKRPTVSELLQHKFITQIEGKDVMLQ 298
>BC034673-1|AAH34673.1| 1332|Homo sapiens misshapen-like kinase 1
(zebrafish) protein.
Length = 1332
Score = 140 bits (340), Expect = 1e-32
Identities = 81/187 (43%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA 98
V N E IA + +E+L+GL + H++ IHRD+K N+LL E+ V+L DFGVSA
Sbjct: 117 VKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSA 176
Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSFGITAIEMATGTA 154
L R + R R+TF+GTP WMAPEV+ D YD+++DIWS GITAIEMA G
Sbjct: 177 QL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
Query: 155 PYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATEL 214
P PM+ L L +N PP L + K + K F I CL K RP +L
Sbjct: 232 PLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFIDFIDTCLIKTYLSRPPTEQL 283
Query: 215 LKHPFFK 221
LK PF +
Sbjct: 284 LKFPFIR 290
>AY775058-1|AAV41830.1| 1312|Homo sapiens misshapen/NIKs-related
kinase isoform beta protein.
Length = 1312
Score = 140 bits (340), Expect = 1e-32
Identities = 81/187 (43%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA 98
V N E IA + +E+L+GL + H++ IHRD+K N+LL E+ V+L DFGVSA
Sbjct: 117 VKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSA 176
Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSFGITAIEMATGTA 154
L R + R R+TF+GTP WMAPEV+ D YD+++DIWS GITAIEMA G
Sbjct: 177 QL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
Query: 155 PYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATEL 214
P PM+ L L +N PP L + K + K F I CL K RP +L
Sbjct: 232 PLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFIDFIDTCLIKTYLSRPPTEQL 283
Query: 215 LKHPFFK 221
LK PF +
Sbjct: 284 LKFPFIR 290
>AB041926-1|BAA94838.1| 1303|Homo sapiens GCK family kinase MINK-2
protein.
Length = 1303
Score = 140 bits (340), Expect = 1e-32
Identities = 81/187 (43%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA 98
V N E IA + +E+L+GL + H++ IHRD+K N+LL E+ V+L DFGVSA
Sbjct: 117 VKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSA 176
Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSFGITAIEMATGTA 154
L R + R R+TF+GTP WMAPEV+ D YD+++DIWS GITAIEMA G
Sbjct: 177 QL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
Query: 155 PYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATEL 214
P PM+ L L +N PP L + K + K F I CL K RP +L
Sbjct: 232 PLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFIDFIDTCLIKTYLSRPPTEQL 283
Query: 215 LKHPFFK 221
LK PF +
Sbjct: 284 LKFPFIR 290
>AB035698-1|BAA90753.1| 1295|Homo sapiens Misshapen/NIK-related
kinase MINK-1 protein.
Length = 1295
Score = 140 bits (340), Expect = 1e-32
Identities = 81/187 (43%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSA 98
V N E IA + +E+L+GL + H++ IHRD+K N+LL E+ V+L DFGVSA
Sbjct: 117 VKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVLLTENAEVKLVDFGVSA 176
Query: 99 WLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHG----YDFKADIWSFGITAIEMATGTA 154
L R + R R+TF+GTP WMAPEV+ D YD+++DIWS GITAIEMA G
Sbjct: 177 QL--DRTVGR---RNTFIGTPYWMAPEVIACDENPDATYDYRSDIWSLGITAIEMAEGAP 231
Query: 155 PYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATEL 214
P PM+ L L +N PP L + K + K F I CL K RP +L
Sbjct: 232 PLCDMHPMRALFLIPRNPPPRLKS--------KKWSKKFIDFIDTCLIKTYLSRPPTEQL 283
Query: 215 LKHPFFK 221
LK PF +
Sbjct: 284 LKFPFIR 290
>BC071579-1|AAH71579.1| 873|Homo sapiens MAP4K3 protein protein.
Length = 873
Score = 140 bits (339), Expect = 1e-32
Identities = 82/195 (42%), Positives = 116/195 (59%), Gaps = 16/195 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y HS G++HRD+K NILL ++G V+LADFGVSA +
Sbjct: 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITA 163
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+A P
Sbjct: 164 --TIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH 218
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + +F + L K+P KRPTA +LL+HP
Sbjct: 219 PMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKRPTAEKLLQHP 271
Query: 219 FFKKAKDRKYLTQTL 233
F + R + L
Sbjct: 272 FVTQHLTRSLAIELL 286
>AF445413-2|AAN75850.1| 873|Homo sapiens MAP4K3 protein.
Length = 873
Score = 140 bits (339), Expect = 1e-32
Identities = 82/195 (42%), Positives = 116/195 (59%), Gaps = 16/195 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y HS G++HRD+K NILL ++G V+LADFGVSA +
Sbjct: 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITA 163
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+A P
Sbjct: 164 --TIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH 218
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + +F + L K+P KRPTA +LL+HP
Sbjct: 219 PMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKRPTAEKLLQHP 271
Query: 219 FFKKAKDRKYLTQTL 233
F + R + L
Sbjct: 272 FVTQHLTRSLAIELL 286
>AF445413-1|AAN75849.1| 894|Homo sapiens MAP4K3 protein.
Length = 894
Score = 140 bits (339), Expect = 1e-32
Identities = 82/195 (42%), Positives = 116/195 (59%), Gaps = 16/195 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y HS G++HRD+K NILL ++G V+LADFGVSA +
Sbjct: 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITA 163
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+A P
Sbjct: 164 --TIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH 218
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + +F + L K+P KRPTA +LL+HP
Sbjct: 219 PMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKRPTAEKLLQHP 271
Query: 219 FFKKAKDRKYLTQTL 233
F + R + L
Sbjct: 272 FVTQHLTRSLAIELL 286
>AF000145-1|AAC15472.1| 884|Homo sapiens germinal center kinase
related protein kinase protein.
Length = 884
Score = 140 bits (339), Expect = 1e-32
Identities = 82/195 (42%), Positives = 116/195 (59%), Gaps = 16/195 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y HS G++HRD+K NILL ++G V+LADFGVSA +
Sbjct: 94 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITA 153
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+A P
Sbjct: 154 --TIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH 208
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + +F + L K+P KRPTA +LL+HP
Sbjct: 209 PMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKRPTAEKLLQHP 261
Query: 219 FFKKAKDRKYLTQTL 233
F + R + L
Sbjct: 262 FVTQHLTRSLAIELL 276
>AC007684-1|AAF19240.1| 712|Homo sapiens unknown protein.
Length = 712
Score = 140 bits (339), Expect = 1e-32
Identities = 82/195 (42%), Positives = 116/195 (59%), Gaps = 16/195 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y HS G++HRD+K NILL ++G V+LADFGVSA +
Sbjct: 104 VTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITA 163
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+A P
Sbjct: 164 --TIAKRK---SFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLH 218
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + +F + L K+P KRPTA +LL+HP
Sbjct: 219 PMRALFLMTKSNFQPPKL------KDKMK-WSNSFHHFVKMALTKNPKKRPTAEKLLQHP 271
Query: 219 FFKKAKDRKYLTQTL 233
F + R + L
Sbjct: 272 FVTQHLTRSLAIELL 286
>AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant
MYO3B.5 protein.
Length = 1192
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant
MYO3B.4 protein.
Length = 1275
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant
MYO3B.3 protein.
Length = 1314
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant
MYO3B.2 protein.
Length = 1341
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant
MYO3B.1 protein.
Length = 1251
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein.
Length = 1278
Score = 140 bits (338), Expect = 2e-32
Identities = 88/214 (41%), Positives = 116/214 (54%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L EK + + F I CL
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL--LHPEK-----WCEEFNHFISQCL 274
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 275 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 308
>AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens
cDNA FLJ31216 fis, clone KIDNE2004084, moderately
similar to Morone saxatilis myosin heavy chain FM3A
(FM3A) mRNA. ).
Length = 1113
Score = 139 bits (337), Expect = 2e-32
Identities = 86/214 (40%), Positives = 115/214 (53%), Gaps = 20/214 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 120 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 175
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 176 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 230
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCL 201
GITAIE+ G P P+K L +N PP L + + + F I CL
Sbjct: 231 LGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTL-------LHPERWCEEFNHFISQCL 283
Query: 202 QKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVA 235
KD +RP+ T LL HPF K + Q +A
Sbjct: 284 IKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLA 317
>BC047865-1|AAH47865.1| 812|Homo sapiens MAP4K2 protein protein.
Length = 812
Score = 139 bits (336), Expect = 3e-32
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 16/193 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G +E IA V +E LKGL + HS G+IHRD+K N+LL G V+LADFGVS L
Sbjct: 106 GPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTA-- 163
Query: 105 DMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
S K R +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+ P PM
Sbjct: 164 --SVAK-RRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPM 220
Query: 163 KVLMLTLQN--DPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF 220
+ LML ++ PP L +D+ + + + F + L K+P KRPTA +LL+HPF
Sbjct: 221 RALMLMSKSSFQPPKL------RDKTR-WTQNFHHFLKLALTKNPKKRPTAEKLLQHPFT 273
Query: 221 KKAKDRKYLTQTL 233
+ R LTQ L
Sbjct: 274 TQQLPRALLTQLL 286
>U07349-1|AAA20968.1| 819|Homo sapiens GC kinase protein.
Length = 819
Score = 138 bits (333), Expect = 7e-32
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 16/193 (8%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G +E IA V +E LKGL + HS G+IHRD+K N+LL G V+LADFGVS L
Sbjct: 105 GPLEERQIAYVCRERLKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTA-- 162
Query: 105 DMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
S K R +F+GTP WMAPEV +E+ GY+ D+W+ GITAIE+ P PM
Sbjct: 163 --SVAK-RRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPM 219
Query: 163 KVLMLTLQN--DPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF 220
+ LML ++ PP L +D+ + + + F + L K+P KRPTA +LL+HPF
Sbjct: 220 RALMLMSKSSFQPPKL------RDKTR-WTQNFHHFLKLALTKNPKKRPTAEKLLQHPFT 272
Query: 221 KKAKDRKYLTQTL 233
+ R LTQ L
Sbjct: 273 TQQLPRALLTQLL 285
>BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 135 bits (327), Expect = 4e-31
Identities = 82/183 (44%), Positives = 103/183 (56%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 121 EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 173
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 174 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein.
Length = 898
Score = 135 bits (327), Expect = 4e-31
Identities = 82/183 (44%), Positives = 103/183 (56%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 121 EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 173
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 174 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase
protein.
Length = 898
Score = 135 bits (327), Expect = 4e-31
Identities = 82/183 (44%), Positives = 103/183 (56%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 121 EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 173
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 174 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 135 bits (327), Expect = 4e-31
Identities = 82/183 (44%), Positives = 103/183 (56%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 121 EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 173
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 174 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein.
Length = 898
Score = 135 bits (327), Expect = 4e-31
Identities = 82/183 (44%), Positives = 103/183 (56%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 121 EVEIAAITHGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 173
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 174 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 134 bits (325), Expect = 6e-31
Identities = 82/183 (44%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A
Sbjct: 121 EVEIAAITHGALHGLTYLHSHALIHRDIKAGNILLTEPGQVKLADFG-SASMA------- 172
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K DIWS GIT IE+A P M L
Sbjct: 173 -PPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITCIELAERKPPLFNMNAMSALY 231
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QND P L Q + +FR+ + CLQK P +RPT+ ELL+H F ++ +
Sbjct: 232 HIAQNDSPTL--------QSNEWTDSFRRFVDYCLQKIPQERPTSAELLRHDFVRRDRPL 283
Query: 227 KYL 229
+ L
Sbjct: 284 RVL 286
>U77129-1|AAB48435.1| 846|Homo sapiens KHS1 protein.
Length = 846
Score = 134 bits (324), Expect = 8e-31
Identities = 78/181 (43%), Positives = 108/181 (59%), Gaps = 16/181 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y H+ G++HRD+K NILL + G V+LADFGV+A +
Sbjct: 108 VTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITA 167
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E++ GY+ DIW+ GITAIE+ P
Sbjct: 168 --TIAKRK---SFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLH 222
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + TF + L K+P KRPTA LL H
Sbjct: 223 PMRALFLMSKSNFQPPKL------KDKTK-WSSTFHNFVKIALTKNPKKRPTAERLLTHT 275
Query: 219 F 219
F
Sbjct: 276 F 276
>BC036013-1|AAH36013.1| 846|Homo sapiens mitogen-activated protein
kinase kinase kinase kinase 5 protein.
Length = 846
Score = 134 bits (324), Expect = 8e-31
Identities = 78/181 (43%), Positives = 108/181 (59%), Gaps = 16/181 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E IA V +E L+GL Y H+ G++HRD+K NILL + G V+LADFGV+A +
Sbjct: 108 VTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITA 167
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
++++K +F+GTP WMAPEV +E++ GY+ DIW+ GITAIE+ P
Sbjct: 168 --TIAKRK---SFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLH 222
Query: 161 PMKVLMLTLQND--PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHP 218
PM+ L L +++ PP L KD+ K + TF + L K+P KRPTA LL H
Sbjct: 223 PMRALFLMSKSNFQPPKL------KDKTK-WSSTFHNFVKIALTKNPKKRPTAERLLTHT 275
Query: 219 F 219
F
Sbjct: 276 F 276
>BX538345-1|CAD98108.1| 1582|Homo sapiens hypothetical protein
protein.
Length = 1582
Score = 133 bits (322), Expect = 1e-30
Identities = 75/211 (35%), Positives = 122/211 (57%), Gaps = 23/211 (10%)
Query: 27 GSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGED 86
GS+ DV+ R+++ N E IA + +E+L+GL + H++ IHRD+K N+LL +
Sbjct: 135 GSVTDVV----RMTS--NQSLKEGWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHN 188
Query: 87 GTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD----HGYDFKADIWSF 142
V+L DFGVSA ++ R R R++F+GTP WMAPEV++ D YD+++D+WS
Sbjct: 189 AEVKLVDFGVSAQVS--RTNGR---RNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSV 243
Query: 143 GITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQ 202
GITAIEMA G P P++ L + L+ P + + + + F + C
Sbjct: 244 GITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKS--------SGWSRKFHNFMEKCTI 295
Query: 203 KDPTKRPTATELLKHPFFKKAKDRKYLTQTL 233
K+ RPT+ +L+HPF + K+ +++ ++L
Sbjct: 296 KNFLFRPTSANMLQHPFVRDIKNERHVVESL 326
>BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein.
Length = 1001
Score = 132 bits (320), Expect = 3e-30
Identities = 81/183 (44%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L+GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 125 EVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 177
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 178 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QN+ P L + +++ Y FR + CLQK P RPT+ ELLKH F + +
Sbjct: 236 HIAQNESPTL-----QSNEWSDY---FRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPE 287
Query: 227 KYL 229
L
Sbjct: 288 TVL 290
>AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase
TAO1 protein.
Length = 1001
Score = 132 bits (320), Expect = 3e-30
Identities = 81/183 (44%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L+GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 125 EVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 177
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 178 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QN+ P L + +++ Y FR + CLQK P RPT+ ELLKH F + +
Sbjct: 236 HIAQNESPTL-----QSNEWSDY---FRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPE 287
Query: 227 KYL 229
L
Sbjct: 288 TVL 290
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 132 bits (320), Expect = 3e-30
Identities = 92/224 (41%), Positives = 114/224 (50%), Gaps = 33/224 (14%)
Query: 1 MAASTNTNTIPWSNTEDDYEIGDVI--------GGSLLDVIKHKIRVSNCVNGVFDEATI 52
M + N N + N D Y +GD + GGSL DV+ C+ DE I
Sbjct: 319 MRENKNPNIV---NYLDSYLVGDELWVVMEYLAGGSLTDVV-----TETCM----DEGQI 366
Query: 53 ATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVR 112
A V +E L+ LE+ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R
Sbjct: 367 AAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKR 421
Query: 113 HTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
T VGTP WMAPEV+ + Y K DIWS GI AIEM G PY P++ L L N
Sbjct: 422 STMVGTPYWMAPEVVTR-KAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG 480
Query: 173 PPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
P L EK FR + CL+ D KR +A ELL+
Sbjct: 481 TPELQN--PEK-----LSAIFRDFLNRCLEMDVEKRGSAKELLQ 517
>AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein.
Length = 1005
Score = 132 bits (320), Expect = 3e-30
Identities = 81/183 (44%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L+GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 129 EVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 181
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 182 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 239
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QN+ P L + +++ Y FR + CLQK P RPT+ ELLKH F + +
Sbjct: 240 HIAQNESPTL-----QSNEWSDY---FRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPE 291
Query: 227 KYL 229
L
Sbjct: 292 TVL 294
>U66464-1|AAB97983.1| 833|Homo sapiens hematopoietic progenitor
kinase protein.
Length = 833
Score = 132 bits (319), Expect = 3e-30
Identities = 79/179 (44%), Positives = 106/179 (59%), Gaps = 16/179 (8%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
V G E I+ V +EVL+GL Y HS +IHRD+K NIL+ + G V+LADFG+SA +
Sbjct: 105 VTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQI-- 162
Query: 103 GRDMSRQKVRHTFVGTPCWMAPEV--MEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP 160
G ++R R +F+GTP WMAPEV + GY+ DIWS GITAIE+A P
Sbjct: 163 GATLAR---RLSFIGTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVH 219
Query: 161 PMKVLMLTLQN--DPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
P++VL L ++ PP L +EK ++ A F I L K P KRP+AT++L H
Sbjct: 220 PLRVLFLMTKSGYQPPRL----KEKGKWSA---AFHNFIKVTLTKSPKKRPSATKMLSH 271
>AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein.
Length = 1001
Score = 132 bits (319), Expect = 3e-30
Identities = 81/183 (44%), Positives = 102/183 (55%), Gaps = 19/183 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA + L+GL Y HS+ IHRD+KAGNILL E G V+LADFG SA +A+
Sbjct: 125 EVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFG-SASMAS------ 177
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 178 --PANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKDR 226
QN+ P L + +++ Y FR + CLQK P RPT+ ELLKH F + +
Sbjct: 236 HIAQNESPTL-----QSNEWSDY---FRNSVDSCLQKIPQDRPTSEELLKHIFVLRERPE 287
Query: 227 KYL 229
L
Sbjct: 288 TVL 290
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 309 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 363
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 364 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 419
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 420 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 464
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 125 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 179
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 180 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 236 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 280
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 125 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 179
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 180 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 236 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 280
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 125 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 179
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 180 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 236 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 280
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 125 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 179
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 180 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 235
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 236 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 280
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 131 bits (317), Expect = 6e-30
Identities = 78/173 (45%), Positives = 95/173 (54%), Gaps = 19/173 (10%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E IA V L+GL Y HS+ IHRDVKAGNILL E G V+L DFG ++ +A
Sbjct: 140 EVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPA----- 194
Query: 109 QKVRHTFVGTPCWMAPEV-MEQDHG-YDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
++FVGTP WMAPEV + D G YD K D+WS GIT IE+A P M L
Sbjct: 195 ----NSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALY 250
Query: 167 LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPF 219
QN+ P L +G + + FR + CLQK P RPT+ LLKH F
Sbjct: 251 HIAQNESPVLQSG--------HWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRF 295
>BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein.
Length = 501
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 310 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 360
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 361 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 414
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 415 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 467
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 468 AQRATAAELLKHPFLAKA 485
>BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 400 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 450
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 451 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 504
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 505 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 557
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 558 AQRATAAELLKHPFLAKA 575
>BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 591
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 400 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 450
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 451 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 504
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 505 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 557
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 558 AQRATAAELLKHPFLAKA 575
>BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated
kinase 4 protein.
Length = 426
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 235 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 285
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 286 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 339
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 340 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 392
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 393 AQRATAAELLKHPFLAKA 410
>AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens
cDNA FLJ90247 fis, clone NT2RM2001902, highly similar to
Homo sapiens mRNA for PAK4 protein. ).
Length = 240
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 49 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 99
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 100 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 153
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 154 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 206
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 207 AQRATAAELLKHPFLAKA 224
>AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein.
Length = 591
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 400 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 450
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 451 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 504
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 505 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 557
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 558 AQRATAAELLKHPFLAKA 575
>AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase
protein.
Length = 591
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 400 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 450
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 451 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 504
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 505 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 557
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 558 AQRATAAELLKHPFLAKA 575
>AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein.
Length = 467
Score = 128 bits (310), Expect = 4e-29
Identities = 78/198 (39%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IA V VL+ L H+ G IHRD+K+ +ILL
Sbjct: 276 GGALTDIVTHTR---------MNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTH 326
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +++ R+K + VGTP WMAPE++ + Y + DIWS GI
Sbjct: 327 DGRVKLSDFGFCAQVS--KEVPRRK---SLVGTPYWMAPELISR-LPYGPEVDIWSLGIM 380
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP+K + + N PP L K+ +K + + + L +DP
Sbjct: 381 VIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL------KNLHKV-SPSLKGFLDRLLVRDP 433
Query: 206 TKRPTATELLKHPFFKKA 223
+R TA ELLKHPF KA
Sbjct: 434 AQRATAAELLKHPFLAKA 451
>BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 528 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 578
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 579 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 632
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 633 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 685
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 686 SQRATAQELLGHPFLKLA 703
>AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 528 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 578
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 579 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 632
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 633 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 685
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 686 SQRATAQELLGHPFLKLA 703
>AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 528 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 578
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 579 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 632
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 633 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 685
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 686 SQRATAQELLGHPFLKLA 703
>AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated
kinase 7 protein.
Length = 719
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 528 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 578
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 579 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 632
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 633 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 685
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 686 SQRATAQELLGHPFLKLA 703
>AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5
protein.
Length = 719
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 528 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 578
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 579 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 632
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 633 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 685
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 686 SQRATAQELLGHPFLKLA 703
>AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein.
Length = 753
Score = 126 bits (303), Expect = 3e-28
Identities = 76/198 (38%), Positives = 110/198 (55%), Gaps = 22/198 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ H +E IATV VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 562 GGALTDIVTHTR---------MNEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTS 612
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG ++L+DFG A ++ +++ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 613 DGRIKLSDFGFCAQVS--KEVPKRK---SLVGTPYWMAPEVISR-LPYGTEVDIWSLGIM 666
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY PP++ + + PP + KD +K R + L ++P
Sbjct: 667 VIEMIDGEPPYFNEPPLQAMRRIRDSLPPRV------KDLHKV-SSVLRGFLDLMLVREP 719
Query: 206 TKRPTATELLKHPFFKKA 223
++R TA ELL HPF K A
Sbjct: 720 SQRATAQELLGHPFLKLA 737
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 125 bits (301), Expect = 5e-28
Identities = 81/222 (36%), Positives = 117/222 (52%), Gaps = 19/222 (8%)
Query: 24 VIGGSLLDVIKHKIR--VSNCVNGV-FDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGN 80
++G L V+++ R +++ V DEA IA V +E L+ LE+ H+N IHRD+K+ +
Sbjct: 72 LVGDELFVVVEYLARGSLTDVVTETCMDEAQIAAVCRESLQALEFLHANQVIHRDIKSDS 131
Query: 81 ILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIW 140
+LLG +G+V+L DFG A + Q R T + TP WMAPEV+ + Y K ++W
Sbjct: 132 VLLGMEGSVKLTDFGFCAQIT-----PEQSKRSTVIRTPYWMAPEVVTR-KAYGPKVNVW 185
Query: 141 SFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDC 200
S GI A EM G PY P++ L L N P L + FR C
Sbjct: 186 SLGIMATEMVEGEPPYLNENPLRALCLIATNGIPELQNP-------ETLSPIFRDR---C 235
Query: 201 LQKDPTKRPTATELLKHPFFKKAKDRKYLTQTLVAIGPSMET 242
L+ D KR +A ELL+H F K AK LT ++A +M++
Sbjct: 236 LETDVEKRGSAKELLQHLFLKLAKLLSSLTPLIMAAKEAMKS 277
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 124 bits (298), Expect = 1e-27
Identities = 76/194 (39%), Positives = 110/194 (56%), Gaps = 22/194 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ ++R++ E IATV + VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 486 GGALTDIVS-QVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTL 536
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +D+ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 537 DGRVKLSDFGFCAQIS--KDVPKRK---SLVGTPYWMAPEVISRSL-YATEVDIWSLGIM 590
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY P++ + + PP L K+ +K R + L +DP
Sbjct: 591 VIEMVDGEPPYFSDSPVQAMKRLRDSPPPKL------KNSHKV-SPVLRDFLERMLVRDP 643
Query: 206 TKRPTATELLKHPF 219
+R TA ELL HPF
Sbjct: 644 QERATAQELLDHPF 657
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 124 bits (298), Expect = 1e-27
Identities = 76/194 (39%), Positives = 110/194 (56%), Gaps = 22/194 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ ++R++ E IATV + VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 486 GGALTDIVS-QVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTL 536
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +D+ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 537 DGRVKLSDFGFCAQIS--KDVPKRK---SLVGTPYWMAPEVISRSL-YATEVDIWSLGIM 590
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY P++ + + PP L K+ +K R + L +DP
Sbjct: 591 VIEMVDGEPPYFSDSPVQAMKRLRDSPPPKL------KNSHKV-SPVLRDFLERMLVRDP 643
Query: 206 TKRPTATELLKHPF 219
+R TA ELL HPF
Sbjct: 644 QERATAQELLDHPF 657
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 124 bits (298), Expect = 1e-27
Identities = 76/194 (39%), Positives = 110/194 (56%), Gaps = 22/194 (11%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GG+L D++ ++R++ E IATV + VL+ L Y H+ G IHRD+K+ +ILL
Sbjct: 486 GGALTDIVS-QVRLN--------EEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTL 536
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGIT 145
DG V+L+DFG A ++ +D+ ++K + VGTP WMAPEV+ + Y + DIWS GI
Sbjct: 537 DGRVKLSDFGFCAQIS--KDVPKRK---SLVGTPYWMAPEVISRSL-YATEVDIWSLGIM 590
Query: 146 AIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDP 205
IEM G PY P++ + + PP L K+ +K R + L +DP
Sbjct: 591 VIEMVDGEPPYFSDSPVQAMKRLRDSPPPKL------KNSHKV-SPVLRDFLERMLVRDP 643
Query: 206 TKRPTATELLKHPF 219
+R TA ELL HPF
Sbjct: 644 QERATAQELLDHPF 657
>AF087893-1|AAP97192.1| 295|Homo sapiens DCHT2 protein.
Length = 295
Score = 122 bits (294), Expect = 4e-27
Identities = 56/103 (54%), Positives = 76/103 (73%), Gaps = 1/103 (0%)
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
MKVLMLTLQNDPP+L+TG ++K+ K YGK+FRKMI CLQKDP KRPTA ELL+H FF+
Sbjct: 1 MKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQ 60
Query: 222 KAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KAK++++L + + P++ R K ++ + GRLH+T G
Sbjct: 61 KAKNKEFLQEKTLQRAPTISERARKV-RRVPGSGGRLHKTEDG 102
Score = 79.4 bits (187), Expect = 3e-14
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NS+ ELNDIRFE+ G+DTAEG++ EL+ AGL+D D V +++NL K++
Sbjct: 205 VLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVE----- 259
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
+ +++TF L S + DD LIGFAQ++I
Sbjct: 260 EPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSI 294
>AF017635-1|AAB70552.1| 267|Homo sapiens DCHT protein.
Length = 267
Score = 122 bits (293), Expect = 5e-27
Identities = 58/103 (56%), Positives = 75/103 (72%), Gaps = 1/103 (0%)
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
MKVLMLTLQNDPP L+TG E+K+ K YGK+FRK++ CLQKDP+KRPTA ELLK FF+
Sbjct: 1 MKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQ 60
Query: 222 KAKDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMTG 264
KAK+R+YL + L+ P + R K ++ +SG LH+T G
Sbjct: 61 KAKNREYLIEKLLTRTPDIAQRAKKV-RRVPGSSGHLHKTEDG 102
Score = 78.2 bits (184), Expect = 8e-14
Identities = 42/95 (44%), Positives = 65/95 (68%), Gaps = 6/95 (6%)
Query: 498 MLQLQNSRGELNDIRFEYVIGKDTAEGIASELVGAGLIDPNDSVPISSNLAKLLNGHVAA 557
+L+L+NSR ELNDIRFE+ G+DTA+G++ EL AGL+D +D V +++NL K+++
Sbjct: 177 VLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDD---- 232
Query: 558 MQTAPKAITFHLNSS-RPNQTYDDKALIGFAQITI 591
A K +TF L S ++ D+ LIGFAQ+++
Sbjct: 233 -PKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSV 266
>BC045538-1|AAH45538.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 113 bits (273), Expect = 1e-24
Identities = 68/151 (45%), Positives = 89/151 (58%), Gaps = 13/151 (8%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
GITAIE+ G P PM+ L ++D
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRSD 246
>BC036079-1|AAH36079.1| 247|Homo sapiens MYO3A protein protein.
Length = 247
Score = 113 bits (273), Expect = 1e-24
Identities = 68/151 (45%), Positives = 89/151 (58%), Gaps = 13/151 (8%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
GITAIE+ G P PM+ L ++D
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRSD 246
>AL358612-3|CAH73816.1| 247|Homo sapiens myosin IIIA protein.
Length = 247
Score = 113 bits (273), Expect = 1e-24
Identities = 68/151 (45%), Positives = 89/151 (58%), Gaps = 13/151 (8%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ D++K ++ ++ E IA +L E L GL++ H+N IHRDVK NILL
Sbjct: 105 GGSVTDLVKGFLKRGERMS----EPLIAYILHEALMGLQHLHNNKTIHRDVKGNNILLTT 160
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM--EQ--DHGYDFKADIWS 141
+G V+L DFGVSA L + R R+T VGTP WMAPEV+ EQ D YD + D WS
Sbjct: 161 EGGVKLVDFGVSAQLTSTRHR-----RNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWS 215
Query: 142 FGITAIEMATGTAPYHKYPPMKVLMLTLQND 172
GITAIE+ G P PM+ L ++D
Sbjct: 216 LGITAIELGDGDPPLADLHPMRALFKIPRSD 246
>AC114794-1|AAY24159.1| 249|Homo sapiens unknown protein.
Length = 249
Score = 113 bits (273), Expect = 1e-24
Identities = 65/144 (45%), Positives = 86/144 (59%), Gaps = 13/144 (9%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS+ +++K +R + DEA I+ +L L GL++ H+N IHRDVK NILL
Sbjct: 111 GGSVTELVKGLLRCGQRL----DEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTT 166
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVM----EQDHGYDFKADIWS 141
+G V+L DFGVSA L S + R+T VGTP WMAPEV+ + D YD + D+WS
Sbjct: 167 EGGVKLVDFGVSAQLT-----STRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWS 221
Query: 142 FGITAIEMATGTAPYHKYPPMKVL 165
GITAIE+ G P P+K L
Sbjct: 222 LGITAIELGDGDPPLFDMHPVKTL 245
>U17743-1|AAC50127.1| 399|Homo sapiens JNK activating kinase
protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>L36870-1|AAC41719.1| 399|Homo sapiens MAP kinase kinase 4 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>DQ015703-1|AAY22176.1| 399|Homo sapiens mitogen-activated protein
kinase kinase 4 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>CR536564-1|CAG38801.1| 399|Homo sapiens MAP2K4 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>BT019676-1|AAV38482.1| 399|Homo sapiens mitogen-activated protein
kinase kinase 4 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>BC036032-1|AAH36032.1| 399|Homo sapiens mitogen-activated protein
kinase kinase 4 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>AF070090-1|AAC24130.1| 399|Homo sapiens mitogen-activated protein
kinase kinase 1 protein.
Length = 399
Score = 108 bits (260), Expect = 5e-23
Identities = 67/193 (34%), Positives = 101/193 (52%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KRP E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRPKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>AY574905-1|AAT81414.1| 462|Homo sapiens regulated in COPD kinase
transcript variant 5 protein.
Length = 462
Score = 108 bits (259), Expect = 6e-23
Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Query: 39 VSNCVN--GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGV 96
+S+ +N G E K++L+G+ Y H N +HRD+K N++L G ++L DFG
Sbjct: 282 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGC 341
Query: 97 SAWLA-TGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155
+ LA G + + + + GTP WMAPEV+ + GY K+DIWS G T EMATG P
Sbjct: 342 ARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINES-GYGRKSDIWSIGCTVFEMATGKPP 400
Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215
M + + D + F +M CL +D +RP+A +LL
Sbjct: 401 LASMDRMAAMFYI----GAHRGLMPPLPDHFSENAADFVRM---CLTRDQHERPSALQLL 453
Query: 216 KHPFFKKA 223
KH F +++
Sbjct: 454 KHSFLERS 461
>AY574904-1|AAT81413.1| 510|Homo sapiens regulated in COPD kinase
transcript variant 4 protein.
Length = 510
Score = 108 bits (259), Expect = 6e-23
Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Query: 39 VSNCVN--GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGV 96
+S+ +N G E K++L+G+ Y H N +HRD+K N++L G ++L DFG
Sbjct: 330 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGC 389
Query: 97 SAWLA-TGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155
+ LA G + + + + GTP WMAPEV+ + GY K+DIWS G T EMATG P
Sbjct: 390 ARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINES-GYGRKSDIWSIGCTVFEMATGKPP 448
Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215
M + + D + F +M CL +D +RP+A +LL
Sbjct: 449 LASMDRMAAMFYI----GAHRGLMPPLPDHFSENAADFVRM---CLTRDQHERPSALQLL 501
Query: 216 KHPFFKKA 223
KH F +++
Sbjct: 502 KHSFLERS 509
>AY574902-1|AAT81411.1| 1215|Homo sapiens regulated in COPD kinase
transcript variant 2 protein.
Length = 1215
Score = 108 bits (259), Expect = 6e-23
Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Query: 39 VSNCVN--GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGV 96
+S+ +N G E K++L+G+ Y H N +HRD+K N++L G ++L DFG
Sbjct: 1035 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGC 1094
Query: 97 SAWLA-TGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155
+ LA G + + + + GTP WMAPEV+ + GY K+DIWS G T EMATG P
Sbjct: 1095 ARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINES-GYGRKSDIWSIGCTVFEMATGKPP 1153
Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215
M + + D + F +M CL +D +RP+A +LL
Sbjct: 1154 LASMDRMAAMFYI----GAHRGLMPPLPDHFSENAADFVRM---CLTRDQHERPSALQLL 1206
Query: 216 KHPFFKKA 223
KH F +++
Sbjct: 1207 KHSFLERS 1214
>AY574901-1|AAT81410.1| 1328|Homo sapiens regulated in COPD kinase
transcript variant 1 protein.
Length = 1328
Score = 108 bits (259), Expect = 6e-23
Identities = 63/188 (33%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Query: 39 VSNCVN--GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGV 96
+S+ +N G E K++L+G+ Y H N +HRD+K N++L G ++L DFG
Sbjct: 1148 ISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGC 1207
Query: 97 SAWLA-TGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAP 155
+ LA G + + + + GTP WMAPEV+ + GY K+DIWS G T EMATG P
Sbjct: 1208 ARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINES-GYGRKSDIWSIGCTVFEMATGKPP 1266
Query: 156 YHKYPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELL 215
M + + D + F +M CL +D +RP+A +LL
Sbjct: 1267 LASMDRMAAMFYI----GAHRGLMPPLPDHFSENAADFVRM---CLTRDQHERPSALQLL 1319
Query: 216 KHPFFKKA 223
KH F +++
Sbjct: 1320 KHSFLERS 1327
>AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 107 bits (258), Expect = 8e-23
Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++DFG S LA
Sbjct: 178 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA-- 235
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 236 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 292
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 293 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 345
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 346 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 387
>AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 107 bits (258), Expect = 8e-23
Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++DFG S LA
Sbjct: 218 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA-- 275
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 276 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 332
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 333 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 385
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 386 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 427
>AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 788
Score = 107 bits (258), Expect = 8e-23
Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++DFG S LA
Sbjct: 218 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA-- 275
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 276 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 332
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 333 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 385
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 386 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 427
>AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 107 bits (258), Expect = 8e-23
Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++DFG S LA
Sbjct: 178 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA-- 235
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 236 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 292
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 293 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 345
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 346 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 387
>AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens
cDNA FLJ16518 fis, clone NT2RI3007443, moderately
similar to MITOGEN-ACTIVATED PROTEIN KINASE KINASE
KINASE 5 (EC ).
Length = 748
Score = 107 bits (258), Expect = 8e-23
Identities = 73/222 (32%), Positives = 105/222 (47%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++DFG S LA
Sbjct: 178 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLA-- 235
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 236 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 292
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 293 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 345
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 346 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 387
>AF344883-1|AAK29621.1| 354|Homo sapiens serine/threonine protein
kinase MST4a protein.
Length = 354
Score = 106 bits (255), Expect = 2e-22
Identities = 59/111 (53%), Positives = 74/111 (66%), Gaps = 15/111 (13%)
Query: 26 GGSLLDVIKHKIRVSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE 85
GGS LD+++ G FDE IAT+LKE+LKGL+Y HS +IHRD+KA N+LL E
Sbjct: 104 GGSALDLLRA---------GPFDEFQIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSE 154
Query: 86 DGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFK 136
G V+LADFGV+ G+ Q R+TFVGTP WMAPEV++Q YD K
Sbjct: 155 QGDVKLADFGVA-----GQLTDTQIKRNTFVGTPFWMAPEVIQQS-AYDSK 199
Score = 33.9 bits (74), Expect = 1.6
Identities = 16/29 (55%), Positives = 20/29 (68%), Gaps = 1/29 (3%)
Query: 206 TKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+KRPTA ELLKH F K +K YLT+ +
Sbjct: 198 SKRPTAKELLKHKFIVKNSKKTSYLTELI 226
>U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein.
Length = 626
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 459 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 517
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 518 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 575
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 576 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 621
>DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 variant 2 protein.
Length = 622
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 455 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 513
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 514 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 571
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 572 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 617
>DQ445915-1|ABE03013.1| 435|Homo sapiens mitogen-activated protein
kinase kinase 7 gamma 1 protein.
Length = 435
Score = 106 bits (254), Expect = 3e-22
Identities = 65/186 (34%), Positives = 93/186 (50%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++L DFG+S L
Sbjct: 226 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLV 285
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 286 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 339
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 340 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 392
Query: 217 HPFFKK 222
H F K+
Sbjct: 393 HSFIKR 398
>BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 459 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 517
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 518 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 575
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 576 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 621
>BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 459 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 517
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 518 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 575
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 576 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 621
>BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 protein.
Length = 626
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 459 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 517
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 518 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 575
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 576 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 621
>BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for
IMAGE:3506235) protein.
Length = 594
Score = 106 bits (254), Expect = 3e-22
Identities = 67/177 (37%), Positives = 94/177 (53%), Gaps = 16/177 (9%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGR 104
G E+ +++L+G+ Y HSN +HRD+K NIL G V+L DFG S L T
Sbjct: 427 GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQT-I 485
Query: 105 DMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPM-K 163
MS +R + GTP WM+PEV+ + GY KAD+WS G T +EM T P+ +Y M
Sbjct: 486 CMSGTGMR-SVTGTPYWMSPEVISGE-GYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAA 543
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTF-RKMIVDCLQKDPTKRPTATELLKHPF 219
+ + Q P L + E +G+ F R++ V+ Q RP+A ELL H F
Sbjct: 544 IFKIATQPTNPQLPSHISE------HGRDFLRRIFVEARQ-----RPSAEELLTHHF 589
>AF022805-1|AAC26142.1| 419|Homo sapiens c-Jun N-terminal kinase
kinase 2 protein.
Length = 419
Score = 106 bits (254), Expect = 3e-22
Identities = 65/186 (34%), Positives = 93/186 (50%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++L DFG+S L
Sbjct: 210 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLV 269
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 270 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 323
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 324 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 376
Query: 217 HPFFKK 222
H F K+
Sbjct: 377 HSFIKR 382
>AF014401-1|AAB88048.1| 419|Homo sapiens JNK kinase 2 protein.
Length = 419
Score = 106 bits (254), Expect = 3e-22
Identities = 65/186 (34%), Positives = 93/186 (50%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++L DFG+S L
Sbjct: 210 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLV 269
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 270 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 323
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 324 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 376
Query: 217 HPFFKK 222
H F K+
Sbjct: 377 HSFIKR 382
>AF006689-1|AAB97813.1| 401|Homo sapiens Jnkk2 protein.
Length = 401
Score = 106 bits (254), Expect = 3e-22
Identities = 65/186 (34%), Positives = 93/186 (50%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++L DFG+S L
Sbjct: 210 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLV 269
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 270 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 323
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 324 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 376
Query: 217 HPFFKK 222
H F K+
Sbjct: 377 HSFIKR 382
>U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase
kinase kinase 5 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulating
kinase 1 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 protein.
Length = 1374
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 776 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 830
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 831 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 890
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 891 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 943
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 944 KKKTQPKLSAL 954
>AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens
cDNA FLJ16645 fis, clone TESTI4031745, moderately
similar to Mitogen-activated protein kinase kinase
kinase 5 (EC ).
Length = 788
Score = 105 bits (252), Expect = 4e-22
Identities = 72/222 (32%), Positives = 104/222 (46%), Gaps = 15/222 (6%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATG 103
G E TI K++L+GL+Y H N +HRD+K N+L+ G V+++D G S LA
Sbjct: 218 GPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDLGTSKRLA-- 275
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPM 162
TF GT +MAPE+++Q GY ADIWS G T IEMAT P+H+
Sbjct: 276 ---GVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHELGEP 332
Query: 163 KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKK 222
+ M + E + A + F I+ C + DP KR T ELL+ F ++
Sbjct: 333 QAAMFKV----GMFKIHPEIPEALSAEARAF---ILSCFEPDPHKRATTAELLREGFLRQ 385
Query: 223 A-KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGRLHRTMT 263
K +K + GP + ATS H +++
Sbjct: 386 VNKGKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVS 427
>AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated protein
kinase kinase kinase 5 variant protein.
Length = 1455
Score = 105 bits (252), Expect = 4e-22
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 14/191 (7%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E TI K++L+GL+Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 856 NEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLA----- 910
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVL 165
TF GT +MAPE++++ GY ADIWS G T IEMATG P+++ +
Sbjct: 911 GINPCTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAA 970
Query: 166 MLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAKD 225
M + E + A K F I+ C + DP KR A +LL F K +
Sbjct: 971 MFKV----GMFKVHPEIPESMSAEAKAF---ILKCFEPDPDKRACANDLLVDEFLKVSSK 1023
Query: 226 RKYLTQTLVAI 236
+K L A+
Sbjct: 1024 KKKTQPKLSAL 1034
>BC060764-1|AAH60764.1| 399|Homo sapiens mitogen-activated protein
kinase kinase 4 protein.
Length = 399
Score = 104 bits (250), Expect = 8e-22
Identities = 66/193 (34%), Positives = 100/193 (51%), Gaps = 16/193 (8%)
Query: 39 VSNCVNGVFDEATIATVLKEVLKGLEYFHSNGQI-HRDVKAGNILLGEDGTVQLADFGVS 97
V + ++ V E + + +K L + N +I HRD+K NILL G ++L DFG+S
Sbjct: 192 VYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGIS 251
Query: 98 AWLATGRDMSRQKVRHTFVGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTA 154
L +R G +MAPE ++ GYD ++D+WS GIT E+ATG
Sbjct: 252 GQLVDSIAKTRD------AGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRF 305
Query: 155 PYHKYPPM-KVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATE 213
PY K+ + L ++ DPP L + +EE++ + +F + CL KD +KR E
Sbjct: 306 PYPKWNSVFDQLTQVVKGDPPQL-SNSEERE----FSPSFINFVNLCLTKDESKRLKYKE 360
Query: 214 LLKHPFFKKAKDR 226
LLKHPF ++R
Sbjct: 361 LLKHPFILMYEER 373
>AF013589-1|AAC16273.1| 462|Homo sapiens mitogen-activated protein
kinase kinase 7b protein.
Length = 462
Score = 104 bits (250), Expect = 8e-22
Identities = 64/186 (34%), Positives = 92/186 (49%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++ DFG+S L
Sbjct: 253 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKFCDFGISGRLV 312
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 313 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 366
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 367 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 419
Query: 217 HPFFKK 222
H F K+
Sbjct: 420 HSFIKR 425
>AF013588-1|AAC16272.1| 419|Homo sapiens mitogen-activated protein
kinase kinase 7 protein.
Length = 419
Score = 104 bits (250), Expect = 8e-22
Identities = 64/186 (34%), Positives = 92/186 (49%), Gaps = 19/186 (10%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++ DFG+S L
Sbjct: 210 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKFCDFGISGRLV 269
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGITAIEMATGTAPYH 157
+ +R G +MAPE ++ YD +AD+WS GI+ +E+ATG PY
Sbjct: 270 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYK 323
Query: 158 K-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLK 216
+VL LQ +PP L + + F+ + DCL KD KRP +LL+
Sbjct: 324 NCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLE 376
Query: 217 HPFFKK 222
H F K+
Sbjct: 377 HSFIKR 382
>AB102300-1|BAC80799.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102299-1|BAC80798.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102298-1|BAC80797.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102297-1|BAC80796.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102296-1|BAC80795.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102295-1|BAC80794.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102294-1|BAC80793.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102293-1|BAC80792.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102292-1|BAC80791.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102291-1|BAC80790.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102290-1|BAC80789.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102289-1|BAC80788.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102288-1|BAC80787.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102287-1|BAC80786.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102286-1|BAC80785.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102285-1|BAC80784.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102284-1|BAC80783.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102283-1|BAC80782.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102282-1|BAC80781.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>AB102281-1|BAC80780.1| 99|Homo sapiens p21-activated kinase 3
protein.
Length = 99
Score = 100 bits (240), Expect = 1e-20
Identities = 52/104 (50%), Positives = 64/104 (61%), Gaps = 6/104 (5%)
Query: 60 LKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSRQKVRHTFVGTP 119
L+ L++ HSN IHRD+K+ NILLG DG+V+L DFG A + Q R T VGTP
Sbjct: 2 LQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQIT-----PEQSKRSTMVGTP 56
Query: 120 CWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
WMAPEV+ + Y K DIWS GI AIEM G PY P++
Sbjct: 57 YWMAPEVVTR-KAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLR 99
>U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b
protein.
Length = 448
Score = 98.7 bits (235), Expect = 5e-20
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E + + V+KGL Y S +HRDVK N+L+ G V+L DFGVS L
Sbjct: 257 EHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLV------- 309
Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP-------P 161
+ T+VGT +MAPE + + Y +D+WS GI+ +E+A G PY + P
Sbjct: 310 NSIAKTYVGTNAYMAPERISGEQ-YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMP 368
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
+++L + D P L G + + F I C++K P +RP EL+ HPF
Sbjct: 369 LQLLQCIVDEDSPVLPVG--------EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
Query: 222 KAKD 225
+ D
Sbjct: 421 QFND 424
>D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein.
Length = 1626
Score = 98.7 bits (235), Expect = 5e-20
Identities = 63/183 (34%), Positives = 90/183 (49%), Gaps = 15/183 (8%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E I K++ + H +G +HRD+K NI L G ++L DFG S L
Sbjct: 1455 EHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMP 1514
Query: 109 QKVRHTFVGTPCWMAPEVM--EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
+V T +GT +MAPEV+ + G+ ADIWS G IEM TG P+H+Y +M
Sbjct: 1515 GEVNST-LGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIM 1573
Query: 167 --LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAK 224
+ + + PP + + E GK F + CL+ DP R TA++LL H F K
Sbjct: 1574 YKVGMGHKPPIPERLSPE-------GKDF---LSHCLESDPKMRWTASQLLDHSFVKVCT 1623
Query: 225 DRK 227
D +
Sbjct: 1624 DEE 1626
>CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein.
Length = 448
Score = 98.7 bits (235), Expect = 5e-20
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E + + V+KGL Y S +HRDVK N+L+ G V+L DFGVS L
Sbjct: 257 EHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLV------- 309
Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP-------P 161
+ T+VGT +MAPE + + Y +D+WS GI+ +E+A G PY + P
Sbjct: 310 NSIAKTYVGTNAYMAPERISGEQ-YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMP 368
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
+++L + D P L G + + F I C++K P +RP EL+ HPF
Sbjct: 369 LQLLQCIVDEDSPVLPVG--------EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
Query: 222 KAKD 225
+ D
Sbjct: 421 QFND 424
>BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated protein
kinase kinase 5 protein.
Length = 448
Score = 98.7 bits (235), Expect = 5e-20
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E + + V+KGL Y S +HRDVK N+L+ G V+L DFGVS L
Sbjct: 257 EHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLV------- 309
Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP-------P 161
+ T+VGT +MAPE + + Y +D+WS GI+ +E+A G PY + P
Sbjct: 310 NSIAKTYVGTNAYMAPERISGEQ-YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMP 368
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
+++L + D P L G + + F I C++K P +RP EL+ HPF
Sbjct: 369 LQLLQCIVDEDSPVLPVG--------EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
Query: 222 KAKD 225
+ D
Sbjct: 421 QFND 424
>BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated protein
kinase kinase 5 protein.
Length = 448
Score = 98.7 bits (235), Expect = 5e-20
Identities = 61/184 (33%), Positives = 90/184 (48%), Gaps = 23/184 (12%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E + + V+KGL Y S +HRDVK N+L+ G V+L DFGVS L
Sbjct: 257 EHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLV------- 309
Query: 109 QKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYP-------P 161
+ T+VGT +MAPE + + Y +D+WS GI+ +E+A G PY + P
Sbjct: 310 NSIAKTYVGTNAYMAPERISGEQ-YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMP 368
Query: 162 MKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
+++L + D P L G + + F I C++K P +RP EL+ HPF
Sbjct: 369 LQLLQCIVDEDSPVLPVG--------EFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV 420
Query: 222 KAKD 225
+ D
Sbjct: 421 QFND 424
>AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinase
protein.
Length = 1607
Score = 98.7 bits (235), Expect = 5e-20
Identities = 63/183 (34%), Positives = 90/183 (49%), Gaps = 15/183 (8%)
Query: 49 EATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLATGRDMSR 108
E I K++ + H +G +HRD+K NI L G ++L DFG S L
Sbjct: 1436 EHVIRLYSKQITIAINVLHEHGIVHRDIKGANIFLTSSGLIKLGDFGCSVKLKNNAQTMP 1495
Query: 109 QKVRHTFVGTPCWMAPEVM--EQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLM 166
+V T +GT +MAPEV+ + G+ ADIWS G IEM TG P+H+Y +M
Sbjct: 1496 GEVNST-LGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIM 1554
Query: 167 --LTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKAK 224
+ + + PP + + E GK F + CL+ DP R TA++LL H F K
Sbjct: 1555 YKVGMGHKPPIPERLSPE-------GKDF---LSHCLESDPKMRWTASQLLDHSFVKVCT 1604
Query: 225 DRK 227
D +
Sbjct: 1605 DEE 1607
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 310 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 364
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 365 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 424
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 425 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 475
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 476 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 509
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 310 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 364
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 365 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 424
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 425 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 475
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 476 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 509
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 213 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 267
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 268 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 327
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 328 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 378
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 379 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 412
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 467 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 521
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 522 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 581
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 582 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 632
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 633 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 666
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 467 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 521
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 522 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 581
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 582 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 632
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 633 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 666
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 744 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 798
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 799 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 858
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 859 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 909
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 910 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 943
>AK074837-1|BAC11236.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ90356 fis, clone NT2RP2003545, weakly similar to
Homo sapiens STE20-like kinase 3 (mst-3) mRNA. ).
Length = 231
Score = 97.5 bits (232), Expect = 1e-19
Identities = 55/113 (48%), Positives = 69/113 (61%), Gaps = 11/113 (9%)
Query: 122 MAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAE 181
MAPEV++Q YD KADIWS GITAIE+A G P PM+VL L +N+PP L
Sbjct: 1 MAPEVIQQS-AYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL----- 54
Query: 182 EKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ K+F++ I CL KDP+ RPTA ELLKH F K +K YLT+ +
Sbjct: 55 ----VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 103
>AK027589-1|BAB55215.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ14683 fis, clone NT2RP2004768, weakly similar to
SERINE/THREONINE-PROTEIN KINASE NRK1 (EC 2.7.1.-). ).
Length = 231
Score = 97.5 bits (232), Expect = 1e-19
Identities = 55/113 (48%), Positives = 69/113 (61%), Gaps = 11/113 (9%)
Query: 122 MAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQNDPPNLDTGAE 181
MAPEV++Q YD KADIWS GITAIE+A G P PM+VL L +N+PP L
Sbjct: 1 MAPEVIQQS-AYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTL----- 54
Query: 182 EKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFF-KKAKDRKYLTQTL 233
+ K+F++ I CL KDP+ RPTA ELLKH F K +K YLT+ +
Sbjct: 55 ----VGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 103
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 467 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 521
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 522 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 581
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 582 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 632
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 633 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 666
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 648 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 702
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 703 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 762
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 763 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 813
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 814 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 847
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis
signal-regulating kinase 2 protein.
Length = 1288
Score = 97.5 bits (232), Expect = 1e-19
Identities = 65/214 (30%), Positives = 102/214 (47%), Gaps = 18/214 (8%)
Query: 48 DEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGE-DGTVQLADFGVSAWLATGRDM 106
+E+TI+ +++L+GL Y H N +HRD+K N+L+ G ++++DFG S LA
Sbjct: 744 NESTISFYTRQILQGLGYLHDNHIVHRDIKGDNVLINTFSGLLKISDFGTSKRLA----- 798
Query: 107 SRQKVRHTFVGTPCWMAPEVMEQ-DHGYDFKADIWSFGITAIEMATGTAPYHKY--PPMK 163
TF GT +MAPE+++Q GY ADIWS G T IEMATG P+H+ P
Sbjct: 799 GITPCTETFTGTLQYMAPEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAA 858
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFKKA 223
+ + + P + + + Q ++ + DP R +A LL PF +
Sbjct: 859 MFQVGMYKVHPPMPSSLSAEAQ---------AFLLRTFEPDPRLRASAQTLLGDPFLQPG 909
Query: 224 KDRKYLTQTLVAIGPSMETRVTKASKKHSATSGR 257
K + + A PS + +S T +
Sbjct: 910 KRSRSPSSPRHAPRPSDAPSASPTPSANSTTQSQ 943
>BC038295-1|AAH38295.1| 426|Homo sapiens MAP2K7 protein protein.
Length = 426
Score = 97.1 bits (231), Expect = 2e-19
Identities = 65/193 (33%), Positives = 93/193 (48%), Gaps = 26/193 (13%)
Query: 43 VNGVFDEATIATVLKEVLKGLEYF-HSNGQIHRDVKAGNILLGEDGTVQLADFGVSAWLA 101
+ G E + + ++K L Y +G IHRDVK NILL E G ++L DFG+S L
Sbjct: 210 MQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLV 269
Query: 102 TGRDMSRQKVRHTFVGTPCWMAPEVMEQDH----GYDFKADIWSFGI-------TAIEMA 150
+ +R G +MAPE ++ YD +AD+WS GI + +E+A
Sbjct: 270 DSKAKTRS------AGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLPCPSPSQVELA 323
Query: 151 TGTAPYHK-YPPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRP 209
TG PY +VL LQ +PP L + + F+ + DCL KD KRP
Sbjct: 324 TGQFPYKNCKTDFEVLTKVLQEEPPLL-------PGHMGFSGDFQSFVKDCLTKDHRKRP 376
Query: 210 TATELLKHPFFKK 222
+LL+H F K+
Sbjct: 377 KYNKLLEHSFIKR 389
>AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein.
Length = 1495
Score = 97.1 bits (231), Expect = 2e-19
Identities = 60/178 (33%), Positives = 91/178 (51%), Gaps = 8/178 (4%)
Query: 45 GVFDEATIATVLKEVLKGLEYFHSNGQIHRDVKAGNILLGEDG-TVQLADFGVSAWLATG 103
G F E+ + +++L+GL Y H N IHRDVK N+L+ G +++ADFG +A LA+
Sbjct: 1322 GAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLAS- 1380
Query: 104 RDMSRQKVRHTFVGTPCWMAPEVMEQDHGYDFKADIWSFGITAIEMATGTAPYHKYPPMK 163
+ + + +GT +MAPEV+ + Y D+WS G IEMA P++
Sbjct: 1381 KGTGAGEFQGQLLGTIAFMAPEVL-RGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSN 1439
Query: 164 VLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKHPFFK 221
L L + T A + + G R + + CL+ P RP + ELLKHP F+
Sbjct: 1440 HLALIFKIASA---TTAPSIPSHLSPG--LRDVALRCLELQPQDRPPSRELLKHPVFR 1492
>U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein.
Length = 352
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 163 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 221
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 222 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 275
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 276 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 327
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 328 PFFTLHKTKK 337
>U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
>L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein.
Length = 318
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 129 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 187
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 188 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 241
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 242 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 293
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 294 PFFTLHKTKK 303
>D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b
protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
>CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
>CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
>BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
>AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 isoform B variant protein.
Length = 347
Score = 96.7 bits (230), Expect = 2e-19
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 21/190 (11%)
Query: 44 NGVFDEATIATVLKEVLKGLEYFHSN-GQIHRDVKAGNILLGEDGTVQLADFGVSAWLAT 102
N E + + +++ LE+ HS IHRDVK N+L+ ++G V++ DFG+S +L
Sbjct: 158 NMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLV- 216
Query: 103 GRDMSRQKVRHTF-VGTPCWMAPEVMEQD---HGYDFKADIWSFGITAIEMATGTAPYHK 158
V T G +MAPE + + GY+ K+D+WS GIT IEMA PY
Sbjct: 217 ------DSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYES 270
Query: 159 Y-PPMKVLMLTLQNDPPNLDTGAEEKDQYKAYGKTFRKMIVDCLQKDPTKRPTATELLKH 217
+ P + L ++ P L + F CL+K+P +R + EL++H
Sbjct: 271 WGTPFQQLKQVVEEPSPQLPA--------DRFSPEFVDFTAQCLRKNPAERMSYLELMEH 322
Query: 218 PFFKKAKDRK 227
PFF K +K
Sbjct: 323 PFFTLHKTKK 332
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.314 0.130 0.374
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,002,218
Number of Sequences: 224733
Number of extensions: 2189422
Number of successful extensions: 9944
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2287
Number of HSP's successfully gapped in prelim test: 449
Number of HSP's that attempted gapping in prelim test: 3356
Number of HSP's gapped (non-prelim): 3493
length of query: 593
length of database: 73,234,838
effective HSP length: 94
effective length of query: 499
effective length of database: 52,109,936
effective search space: 26002858064
effective search space used: 26002858064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 68 (31.5 bits)
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