Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000553-TA|BGIBMGA000553-PA|IPR002007|Haem peroxidase,
animal, IPR001611|Leucine-rich repeat, IPR007110|Immunoglobulin-like,
IPR003591|Leucine-rich repeat, typical subtype,
IPR000483|Cysteine-rich flanking region, C-terminal,
IPR003599|Immunoglobulin subtype, IPR003598|Immunoglobulin subtype 2,
IPR013098|Immunoglobulin I-set, IPR010255|Haem peroxidase
(1329 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 1108 0.0
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 1108 0.0
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 978 0.0
DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase prot... 549 e-155
J02969-1|AAA61215.1| 933|Homo sapiens TPO protein. 548 e-155
Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for ... 547 e-154
BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase prot... 547 e-154
M25715-1|AAA97517.1| 933|Homo sapiens TPO protein. 546 e-154
AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein. 546 e-154
M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein. 541 e-153
AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isof... 536 e-151
BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog (Dr... 522 e-147
AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens ... 522 e-147
M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase pro... 510 e-143
DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase p... 510 e-143
X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for ... 499 e-140
X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase pr... 499 e-140
S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein. 499 e-140
M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein. 499 e-140
M17176-1|AAA60346.1| 745|Homo sapiens MPO protein. 499 e-140
J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein. 499 e-140
DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein. 499 e-140
BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein. 499 e-140
X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase ... 476 e-133
U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein. 432 e-120
BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein. 432 e-120
BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein. 432 e-120
AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein. 432 e-120
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 419 e-116
AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens ... 396 e-109
X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from... 359 5e-98
J02970-1|AAA61216.1| 876|Homo sapiens TPO protein. 357 1e-97
M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein. 294 1e-78
AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase prot... 281 1e-74
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 178 1e-43
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 177 2e-43
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 176 4e-43
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 176 5e-43
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 175 1e-42
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 172 6e-42
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 172 8e-42
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 172 8e-42
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 172 8e-42
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 172 8e-42
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 172 8e-42
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 171 1e-41
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 166 5e-40
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 166 5e-40
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 166 5e-40
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 166 5e-40
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 163 3e-39
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 163 3e-39
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 163 3e-39
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 163 3e-39
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 163 3e-39
AF027971-1|AAG38481.1| 193|Homo sapiens airway lactoperoxidase ... 163 4e-39
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 161 1e-38
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 159 8e-38
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 159 8e-38
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 159 8e-38
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 158 1e-37
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 158 1e-37
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 157 2e-37
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 154 2e-36
AF533528-1|AAN04471.1| 255|Homo sapiens thyroid peroxidase isof... 154 2e-36
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 152 9e-36
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 152 9e-36
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 151 2e-35
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 150 4e-35
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 150 4e-35
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 149 7e-35
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 147 3e-34
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 144 2e-33
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 144 2e-33
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 144 2e-33
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 143 3e-33
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 143 3e-33
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 143 3e-33
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 143 3e-33
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 143 4e-33
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 141 1e-32
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 141 1e-32
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 141 2e-32
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 141 2e-32
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 140 4e-32
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 139 5e-32
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 139 7e-32
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 138 9e-32
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 138 9e-32
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 138 9e-32
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 138 9e-32
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 138 9e-32
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 138 9e-32
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 138 9e-32
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 138 9e-32
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 138 9e-32
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 138 1e-31
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 138 1e-31
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 138 2e-31
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 138 2e-31
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 137 3e-31
BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein. 136 4e-31
BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein. 136 4e-31
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 136 4e-31
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 136 4e-31
AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1... 136 4e-31
AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein. 136 4e-31
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 136 5e-31
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 136 7e-31
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 136 7e-31
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 136 7e-31
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 135 1e-30
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 135 1e-30
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 135 1e-30
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 135 1e-30
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 134 2e-30
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 134 2e-30
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 134 2e-30
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 134 2e-30
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 134 2e-30
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 134 2e-30
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 134 2e-30
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 134 2e-30
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 134 2e-30
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 134 3e-30
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 134 3e-30
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 134 3e-30
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 132 6e-30
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 132 6e-30
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 132 6e-30
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 132 8e-30
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 132 8e-30
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 132 8e-30
AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH oxidase/... 131 1e-29
AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2... 131 1e-29
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 131 2e-29
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 130 2e-29
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 130 4e-29
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 129 8e-29
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 128 1e-28
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 128 1e-28
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 128 1e-28
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 127 3e-28
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 126 4e-28
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 126 4e-28
AF533531-1|AAN04474.1| 347|Homo sapiens thyroid peroxidase isof... 126 4e-28
AF533530-1|AAN04473.1| 350|Homo sapiens thyroid peroxidase isof... 126 4e-28
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 126 5e-28
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 126 5e-28
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 126 5e-28
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 122 1e-26
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 121 2e-26
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 120 3e-26
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 119 6e-26
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 119 6e-26
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 119 6e-26
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 119 6e-26
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 119 6e-26
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 119 6e-26
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 119 6e-26
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 119 8e-26
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 119 8e-26
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 119 8e-26
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 118 1e-25
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 118 2e-25
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 118 2e-25
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 118 2e-25
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 118 2e-25
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 118 2e-25
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 117 3e-25
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 117 3e-25
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 117 3e-25
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 117 3e-25
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 116 4e-25
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 116 6e-25
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 115 1e-24
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 113 3e-24
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 113 3e-24
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 113 3e-24
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 113 4e-24
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 113 4e-24
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 113 4e-24
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 113 4e-24
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 113 4e-24
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 113 5e-24
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 113 5e-24
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 112 9e-24
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 111 1e-23
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 111 1e-23
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 111 2e-23
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 111 2e-23
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 110 3e-23
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 110 4e-23
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 110 4e-23
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 109 5e-23
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 109 5e-23
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 109 5e-23
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 108 2e-22
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 108 2e-22
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 107 2e-22
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 107 2e-22
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 107 3e-22
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 106 6e-22
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 106 6e-22
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 105 1e-21
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 104 2e-21
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 104 2e-21
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 103 3e-21
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 103 3e-21
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 103 3e-21
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 103 3e-21
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 103 3e-21
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 103 3e-21
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 103 4e-21
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 103 4e-21
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 102 7e-21
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 102 7e-21
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 102 1e-20
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 102 1e-20
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 102 1e-20
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 100 4e-20
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 100 4e-20
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 100 4e-20
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 100 4e-20
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 100 4e-20
AY324322-1|AAQ97217.1| 469|Homo sapiens leucine-rich repeat neu... 100 4e-20
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 100 4e-20
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 100 4e-20
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 100 4e-20
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 99 5e-20
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 99 5e-20
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 100 7e-20
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 100 7e-20
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 99 9e-20
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 99 1e-19
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 99 1e-19
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 98 2e-19
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 98 2e-19
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 98 2e-19
EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3 p... 98 2e-19
BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein. 98 2e-19
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 98 2e-19
AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein. 98 2e-19
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 98 2e-19
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 98 2e-19
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL512424-3|CAI14257.1| 409|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 98 2e-19
AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein. 98 2e-19
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 97 3e-19
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 97 3e-19
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 97 3e-19
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 97 3e-19
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 97 3e-19
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 97 3e-19
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 97 3e-19
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 97 3e-19
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 97 3e-19
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 97 5e-19
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 97 5e-19
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 96 9e-19
AK027500-1|BAB55157.1| 315|Homo sapiens protein ( Homo sapiens ... 95 1e-18
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 95 2e-18
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 95 2e-18
X16455-1|CAA34474.1| 697|Homo sapiens pCEA80-11 protein (647 AA... 95 2e-18
M29540-1|AAA51967.1| 702|Homo sapiens CEA protein. 95 2e-18
M17303-1|AAB59513.1| 702|Homo sapiens CEA protein. 95 2e-18
M15042-1|AAA51963.1| 698|Homo sapiens CEA protein. 95 2e-18
BC034671-1|AAH34671.1| 702|Homo sapiens carcinoembryonic antige... 95 2e-18
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 94 3e-18
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 94 3e-18
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 94 3e-18
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 94 3e-18
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 94 3e-18
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 94 3e-18
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 93 5e-18
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 93 5e-18
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 93 5e-18
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 93 5e-18
AK223101-1|BAD96821.1| 702|Homo sapiens carcinoembryonic antige... 93 5e-18
M16234-1|AAA51972.1| 372|Homo sapiens CEA protein. 93 8e-18
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 92 1e-17
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 92 1e-17
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 92 1e-17
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 92 1e-17
M59262-1|AAA62835.1| 702|Homo sapiens carcinoembryonic antigen ... 91 2e-17
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 91 2e-17
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 91 3e-17
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 91 3e-17
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 91 3e-17
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 91 3e-17
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 91 3e-17
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 91 3e-17
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 91 3e-17
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 91 3e-17
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 91 3e-17
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 91 3e-17
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 91 3e-17
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 91 3e-17
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 90 4e-17
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 90 4e-17
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 90 4e-17
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 90 6e-17
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 90 6e-17
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 89 1e-16
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 89 1e-16
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 89 1e-16
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 89 1e-16
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 89 1e-16
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 89 1e-16
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 89 1e-16
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 89 1e-16
BC027475-1|AAH27475.2| 528|Homo sapiens LRFN4 protein protein. 89 1e-16
BX538014-1|CAD97961.1| 355|Homo sapiens hypothetical protein pr... 89 1e-16
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 89 1e-16
BC019687-1|AAH19687.1| 430|Homo sapiens LRRC4B protein protein. 89 1e-16
AL645724-1|CAI21858.1| 354|Homo sapiens neuronal growth regulat... 89 1e-16
AL627317-1|CAH72391.1| 354|Homo sapiens neuronal growth regulat... 89 1e-16
AL359821-1|CAH70913.1| 354|Homo sapiens neuronal growth regulat... 89 1e-16
AL356600-1|CAI23492.1| 354|Homo sapiens neuronal growth regulat... 89 1e-16
AL354949-1|CAI16869.1| 354|Homo sapiens neuronal growth regulat... 89 1e-16
AK023273-1|BAB14500.1| 431|Homo sapiens protein ( Homo sapiens ... 89 1e-16
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 89 1e-16
AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing g... 88 2e-16
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 88 2e-16
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 88 2e-16
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 88 2e-16
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 88 2e-16
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 88 2e-16
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 88 2e-16
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 87 3e-16
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 87 3e-16
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 87 3e-16
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 87 3e-16
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 87 3e-16
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 87 3e-16
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 87 3e-16
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 87 3e-16
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 87 3e-16
AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion mo... 87 3e-16
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 87 3e-16
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 87 4e-16
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 87 5e-16
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 87 5e-16
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 87 5e-16
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 87 5e-16
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 87 5e-16
AK092307-1|BAC03858.1| 354|Homo sapiens protein ( Homo sapiens ... 86 7e-16
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 86 7e-16
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 86 9e-16
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 86 9e-16
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 86 9e-16
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 86 9e-16
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 85 1e-15
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 85 1e-15
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 85 1e-15
AY358132-1|AAQ88499.1| 352|Homo sapiens DMML2433 protein. 85 1e-15
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 85 1e-15
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 85 1e-15
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 85 1e-15
X52378-1|CAA36604.1| 349|Homo sapiens mature non-specific cross... 85 2e-15
DQ822518-1|ABG46943.1| 349|Homo sapiens carcinoembryonic antige... 85 2e-15
BC026263-1|AAH26263.1| 349|Homo sapiens carcinoembryonic antige... 85 2e-15
AC004558-1|AAC13659.1| 349|Homo sapiens CGM6_HUMAN protein. 85 2e-15
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 84 3e-15
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 84 3e-15
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 84 4e-15
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 84 4e-15
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 84 4e-15
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 84 4e-15
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 84 4e-15
X14831-1|CAA32940.1| 430|Homo sapiens TM2-CEA precursor protein. 83 5e-15
M33326-1|AAA59914.1| 349|Homo sapiens non-specific cross reacti... 83 5e-15
D90064-1|BAA14108.1| 349|Homo sapiens NCA-W272 protein. 83 5e-15
AY766113-1|AAV34600.1| 368|Homo sapiens putative carcinoembryon... 83 5e-15
AC004785-1|AAC18435.1| 430|Homo sapiens BGPb_HUMAN protein. 83 5e-15
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 83 6e-15
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 83 6e-15
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 83 6e-15
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 83 6e-15
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 83 6e-15
BC105999-1|AAI06000.1| 404|Homo sapiens CADM2 protein protein. 83 9e-15
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 82 1e-14
D14466-1|BAA03362.1| 82|Homo sapiens myeloperoxidase protein. 82 1e-14
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 82 1e-14
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 1108 bits (2743), Expect = 0.0
Identities = 561/1266 (44%), Positives = 754/1266 (59%), Gaps = 28/1266 (2%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+RFN I+EI+PG F L L +LLLN+N ++ + SGAF I+ ID
Sbjct: 85 DLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDR 144
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F+ L LEQLYLH N+I ++P++F +LP+L+RL+LHNN++ + G+F + +++L
Sbjct: 145 QAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRL 204
Query: 127 RLDSNALICDCSILWFIRMLEN---NEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQ 183
RLDSN L CDC ILW +L+ + AA C P + G S+A + +L C++P+
Sbjct: 205 RLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPR 264
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN-ENRYEIFDNGTLMVHEA 242
SEP D +V+ G FTC A G P PEI+WLR++ + + ++R + D+GTLM+
Sbjct: 265 ITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNT 324
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
E D G+++CMAKNVAG+ ++ + SPA P FV PQ + E SV
Sbjct: 325 QETDQGIYQCMAKNVAGEVKTQEVTL------RYFGSPARPTFVIQPQNTEVLVGE-SVT 377
Query: 303 FDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+C+ATG P P ++W G+R L + R+ + +G + I+NV D+G Y C N
Sbjct: 378 LECSATGHPPPRISWT-RGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNID 436
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG-N 419
+ A+ + V A P F V P ++ I G V F C+AKG P P I W + L + +
Sbjct: 437 SVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH 496
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
LVLS L + V D Y C+A N G + A LT++ + P P D
Sbjct: 497 LVLSSGT--LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR--VTPVFASIPSDTT 552
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+VQ+PC + P +I W KDG ++ E + I+ G L I +V D GRYEC
Sbjct: 553 VEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECV 612
Query: 540 AFNDYGRDTASVFLTVK--DNLLPGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVN 597
A N G + S+ L+V D GD +V ++ +A+ VD+AI T LF +R N
Sbjct: 613 ARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPN 672
Query: 598 IGDLYRMTRFPNAPER-EVARAAEIYERTLDKLKEYIQSGKKLS-TAEPFNYQSVLSNQH 655
DL + R+P P E ARA EI+ERTL ++E++Q G + ++Y ++S Q+
Sbjct: 673 --DLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQY 730
Query: 656 LEVIARLSGCVAHREEKDCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYEN 715
L +IA LSGC AHR +CSDMC+H KYR+ DG+CNN HPMWG SL+ F R+L +YEN
Sbjct: 731 LNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYEN 790
Query: 716 GFSQPIGWNKDLKYNGFTLPSARLXXXXXXXXXXXXXXXXXXHMTMQWGQWLDHDLDHAL 775
GF+ P G N YNG LP RL HM MQWGQ+LDHDLD +
Sbjct: 791 GFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTV 850
Query: 776 PPVSSQTW-DGVDCKKTCDYAPPCFPIDVPLNDPRVNN-RRCIDFIRXXXXXXXXXXXXL 833
+S + DG C C PPCF + +P ND R + RC+ F+R L
Sbjct: 851 VALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLL 910
Query: 834 FGTLQTREQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSG 893
++ REQINQLTS++DAS VYG + A +RDL + GLLR G KPLLP +
Sbjct: 911 MNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFAT 970
Query: 894 FNGMDCRRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDR 953
+C R+ ES CF+AGD RANEQ+GL +MHT+W REHNRIA +L LNP WDGD
Sbjct: 971 GPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDT 1030
Query: 954 VYQEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFG 1013
+Y E RK+VGA++Q ITY+HWLP ILG G LG+Y YD +N I N FATAA RFG
Sbjct: 1031 IYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFG 1090
Query: 1014 HSLINPVLHRYDENFETIPQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQ 1073
H+L+NP+L+R DENF+ I Q HL L AFFSP+R+V+EGG+DPLLRG+F K++ Q
Sbjct: 1091 HTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQ 1150
Query: 1074 NLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEIS 1133
LN+ELTE+LF AH VALDLAAINIQRGRDH IPPY +R +CN+S + F+DL EI
Sbjct: 1151 LLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIK 1210
Query: 1134 DKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYEN 1193
+ E+R+KL+ LYGS NID++ ++ED V G ++GP CLL QF RLRDGDR WYEN
Sbjct: 1211 NPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYEN 1270
Query: 1194 PSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWA 1253
P VF P QL QIK+TSLARILCDN DNI + +VF + E G SC+++P +DLR W
Sbjct: 1271 PGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQ 1330
Query: 1254 D-CESC 1258
D CE C
Sbjct: 1331 DCCEDC 1336
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated antigen
MG50 protein.
Length = 1496
Score = 1108 bits (2743), Expect = 0.0
Identities = 561/1266 (44%), Positives = 754/1266 (59%), Gaps = 28/1266 (2%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+RFN I+EI+PG F L L +LLLN+N ++ + SGAF I+ ID
Sbjct: 85 DLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDR 144
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F+ L LEQLYLH N+I ++P++F +LP+L+RL+LHNN++ + G+F + +++L
Sbjct: 145 QAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRL 204
Query: 127 RLDSNALICDCSILWFIRMLEN---NEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQ 183
RLDSN L CDC ILW +L+ + AA C P + G S+A + +L C++P+
Sbjct: 205 RLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPR 264
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN-ENRYEIFDNGTLMVHEA 242
SEP D +V+ G FTC A G P PEI+WLR++ + + ++R + D+GTLM+
Sbjct: 265 ITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNT 324
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
E D G+++CMAKNVAG+ ++ + SPA P FV PQ + E SV
Sbjct: 325 QETDQGIYQCMAKNVAGEVKTQEVTL------RYFGSPARPTFVIQPQNTEVLVGE-SVT 377
Query: 303 FDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+C+ATG P P ++W G+R L + R+ + +G + I+NV D+G Y C N
Sbjct: 378 LECSATGHPPPRISWT-RGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNID 436
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG-N 419
+ A+ + V A P F V P ++ I G V F C+AKG P P I W + L + +
Sbjct: 437 SVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH 496
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
LVLS L + V D Y C+A N G + A LT++ + P P D
Sbjct: 497 LVLSSGT--LRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR--VTPVFASIPSDTT 552
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+VQ+PC + P +I W KDG ++ E + I+ G L I +V D GRYEC
Sbjct: 553 VEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECV 612
Query: 540 AFNDYGRDTASVFLTVK--DNLLPGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVN 597
A N G + S+ L+V D GD +V ++ +A+ VD+AI T LF +R N
Sbjct: 613 ARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPN 672
Query: 598 IGDLYRMTRFPNAPER-EVARAAEIYERTLDKLKEYIQSGKKLS-TAEPFNYQSVLSNQH 655
DL + R+P P E ARA EI+ERTL ++E++Q G + ++Y ++S Q+
Sbjct: 673 --DLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYNDLVSPQY 730
Query: 656 LEVIARLSGCVAHREEKDCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYEN 715
L +IA LSGC AHR +CSDMC+H KYR+ DG+CNN HPMWG SL+ F R+L +YEN
Sbjct: 731 LNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFERLLKSVYEN 790
Query: 716 GFSQPIGWNKDLKYNGFTLPSARLXXXXXXXXXXXXXXXXXXHMTMQWGQWLDHDLDHAL 775
GF+ P G N YNG LP RL HM MQWGQ+LDHDLD +
Sbjct: 791 GFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWGQFLDHDLDSTV 850
Query: 776 PPVSSQTW-DGVDCKKTCDYAPPCFPIDVPLNDPRVNN-RRCIDFIRXXXXXXXXXXXXL 833
+S + DG C C PPCF + +P ND R + RC+ F+R L
Sbjct: 851 VALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVRSSPVCGSGMTSLL 910
Query: 834 FGTLQTREQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSG 893
++ REQINQLTS++DAS VYG + A +RDL + GLLR G KPLLP +
Sbjct: 911 MNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQGIVQRSGKPLLPFAT 970
Query: 894 FNGMDCRRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDR 953
+C R+ ES CF+AGD RANEQ+GL +MHT+W REHNRIA +L LNP WDGD
Sbjct: 971 GPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDT 1030
Query: 954 VYQEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFG 1013
+Y E RK+VGA++Q ITY+HWLP ILG G LG+Y YD +N I N FATAA RFG
Sbjct: 1031 IYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFG 1090
Query: 1014 HSLINPVLHRYDENFETIPQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQ 1073
H+L+NP+L+R DENF+ I Q HL L AFFSP+R+V+EGG+DPLLRG+F K++ Q
Sbjct: 1091 HTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQ 1150
Query: 1074 NLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEIS 1133
LN+ELTE+LF AH VALDLAAINIQRGRDH IPPY +R +CN+S + F+DL EI
Sbjct: 1151 LLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIK 1210
Query: 1134 DKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYEN 1193
+ E+R+KL+ LYGS NID++ ++ED V G ++GP CLL QF RLRDGDR WYEN
Sbjct: 1211 NPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYEN 1270
Query: 1194 PSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWA 1253
P VF P QL QIK+TSLARILCDN DNI + +VF + E G SC+++P +DLR W
Sbjct: 1271 PGVFSPAQLTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQ 1330
Query: 1254 D-CESC 1258
D CE C
Sbjct: 1331 DCCEDC 1336
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase protein.
Length = 1463
Score = 978 bits (2422), Expect = 0.0
Identities = 502/1260 (39%), Positives = 709/1260 (56%), Gaps = 28/1260 (2%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+RFN I+EI F L L +LLLN+NH+R + AF G I +D
Sbjct: 56 DLRFNRIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDK 115
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F+ L LE L +++ ++PETF +L RL+RL+LHNNKL IP GSF + L++L
Sbjct: 116 QTFKGLISLEHLVYSFHQLEMLQPETFGDLLRLERLFLHNNKLSKIPAGSFSNLDSLKRL 175
Query: 127 RLDSNALICDCSILWFIRMLEN---NEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQ 183
RLDSNAL+CDC ++W +L+ + AATC P + G ++A++ + CQ P+
Sbjct: 176 RLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPR 235
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLMVHEA 242
EP DVEV G FTC A G P PEI+W+ ++ + L ++ R +FD+GTLM+
Sbjct: 236 ITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNT 295
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
E+D G+++CMA+N AG+A ++ A + PA P FV PQ I TS
Sbjct: 296 RESDQGVYQCMARNSAGEAKTQSAML------RYSSLPAKPSFVIQPQDTEVLIG-TSTT 348
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
+C ATG P P + W + L R + +G + ++N+ D G +TC N HG +
Sbjct: 349 LECMATGHPHPLITWTRDNGLELDGSRHVATSSG-LYLQNITQRDHGRFTCHANNSHGTV 407
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG-NLV 421
A+ + V APP F V P +Q + V + C+A G P P I W + LP+ G + V
Sbjct: 408 QAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTV 467
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
LS L + + D Y C+A + G+ + S LT++ + P+D
Sbjct: 468 LSSGT--LRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAV--FTQLPQDTSVE 523
Query: 482 KETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
++ + C + P I W K+G +I E + + G+L I + D GRYEC A
Sbjct: 524 VGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVAR 583
Query: 542 NDYGRDTASVFLTVK--DNLLPGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIG 599
N +G ++FLTV GD +V ++ A++ VD AI T LF + +
Sbjct: 584 NSFGLAVTNMFLTVTAIQGRQAGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSS-- 641
Query: 600 DLYRMTRFPNAPER-EVARAAEIYERTLDKLKEYIQSGKKLST-AEPFNYQSVLSNQHLE 657
DL +P P E+ARA EI+E TL ++E ++ G + + F Y ++S + L
Sbjct: 642 DLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDLVSPRSLS 701
Query: 658 VIARLSGCVAHREEKDCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGF 717
+IA LSGC A R +CS+ C+H+KYR+ DG+CNN P WG +L+ F R+L P Y +G
Sbjct: 702 LIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGI 761
Query: 718 SQPIGWNKDLKYNGFTLPSARLXXXXXXXXXXXXXXXXXXHMTMQWGQWLDHDLDHALPP 777
P G + LP RL M M WG +L+HDLDH +P
Sbjct: 762 RAPRGLGLPVGSRQ-PLPPPRLVATVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPA 820
Query: 778 VSSQTW-DGVDCKKTCDYAPPCFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGT 836
+S+ + DG C C PPCFP++ DPR + C+ F R +
Sbjct: 821 LSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSATVDS 880
Query: 837 LQTREQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFP-GRKPLLPTSGFN 895
+ REQINQ T+++D S VYG + ++ LRD + GLL+ G +P KPLLP S
Sbjct: 881 VYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGP 940
Query: 896 GMDCRRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVY 955
+C R +ES CF+AGD RANE + LAAMHT+W REHNR+A +L ALNP W+G+ VY
Sbjct: 941 PTECARQEQESP--CFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVY 998
Query: 956 QEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHS 1015
QEARK+VGA++Q ITY HWLP +LG G L Y+ Y+ +N I N FATAA RFGH+
Sbjct: 999 QEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHT 1058
Query: 1016 LINPVLHRYDENFETIPQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNL 1075
LINP+L+R + I +GHL A FSP R++ EGG+DP+LRG+F AK + L
Sbjct: 1059 LINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLL 1118
Query: 1076 NSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDK 1135
+ ELT++LF +A++ A+D AA IQRGRDH IPPY +R FCN++ V +F+DL EI D
Sbjct: 1119 SPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDS 1178
Query: 1136 EVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPS 1195
E+R KL++LYGS +ID+W ++ED + G +VGP CL + QF RLRDGDRFWYENP
Sbjct: 1179 EIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPG 1238
Query: 1196 VFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWADC 1255
VF P QL Q+K+ SL+R+LCDNGD+I + +VF E ++C ++P +DLR W DC
Sbjct: 1239 VFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDC 1298
>DQ011222-1|AAY16985.1| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 549 bits (1354), Expect = e-155
Identities = 286/707 (40%), Positives = 401/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRATEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ +P M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>J02969-1|AAA61215.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 548 bits (1353), Expect = e-155
Identities = 286/707 (40%), Positives = 402/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRRPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ +P M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>Y00406-1|CAA68467.1| 933|Homo sapiens protein ( Human mRNA for
thyroperoxidase. ).
Length = 933
Score = 547 bits (1350), Expect = e-154
Identities = 285/707 (40%), Positives = 402/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ L+LA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLNLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ +P M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 734
>BC095448-1|AAH95448.1| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 547 bits (1349), Expect = e-154
Identities = 285/707 (40%), Positives = 401/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSAAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ + M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>M25715-1|AAA97517.1| 933|Homo sapiens TPO protein.
Length = 933
Score = 546 bits (1347), Expect = e-154
Identities = 285/707 (40%), Positives = 401/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ + M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>AC105450-1|AAX93261.1| 916|Homo sapiens unknown protein.
Length = 916
Score = 546 bits (1347), Expect = e-154
Identities = 285/707 (40%), Positives = 401/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ + M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>M17755-1|AAA61217.2| 933|Homo sapiens thyroid peroxidase protein.
Length = 933
Score = 541 bits (1335), Expect = e-153
Identities = 284/707 (40%), Positives = 399/707 (56%), Gaps = 19/707 (2%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSGAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGSDCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV GR P +P TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHGRLRDSGRAYLPFVPPRAPAACAPEPGNPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSA 1087
+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+LF +
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLS 568
Query: 1088 HAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGS 1147
++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +LY
Sbjct: 569 NSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKH 628
Query: 1148 VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKE 1207
NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R++++
Sbjct: 629 PDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEK 688
Query: 1208 TSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
SL+R++CDN + + + F + + + SC+ + M+L W +
Sbjct: 689 HSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 734
>AB208960-1|BAD92197.1| 864|Homo sapiens thyroid peroxidase isoform d
variant protein.
Length = 864
Score = 536 bits (1322), Expect = e-151
Identities = 276/667 (41%), Positives = 381/667 (57%), Gaps = 18/667 (2%)
Query: 601 LYRMTRFPNAPEREVARAAEIYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIA 660
L ++ P +ARAAEI E ++ +K + L T + + LS L +IA
Sbjct: 2 LLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIA 57
Query: 661 RLSGCVAHREEKDCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQP 720
+SGC+ + C + C +KYR + G+CNN HP WG S + R L P+YE+GFSQP
Sbjct: 58 NMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQP 117
Query: 721 IGWNKDLKYNGFTLPSARLXXXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPV 778
GWN YNGF LP R + + M WGQ++DHD+
Sbjct: 118 RGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQST 177
Query: 779 SSQTWDG-VDCKKTCDYAPPCFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTL 837
S + G DC+ TC+ PCFPI +P C+ F R LFG L
Sbjct: 178 SKAAFGGGSDCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNL 237
Query: 838 QT---REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLP 890
T R+Q+N LTSFLDAS VYG ++ LR+ T+ GLLRV A GR P +P
Sbjct: 238 STANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVP 297
Query: 891 TSGFNGMDCRRNLEESTRS-CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFW 949
+ TR CF+AGD RA+E L A+HT+W+REHNR+A LKALN W
Sbjct: 298 PRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHW 357
Query: 950 DGDRVYQEARKVVGAQMQFITYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATA 1008
D VYQEARKVVGA Q IT ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TA
Sbjct: 358 SADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTA 417
Query: 1009 ALRFGHSLINPVLHRYDENFETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAK 1067
A RFGH+ I+P++ R D +F+ P L L AFFSPW L+ GG+DPL+RG+ PAK
Sbjct: 418 AFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAK 477
Query: 1068 LKTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDD 1127
L+ Q +N ELTE+LF +++ LDLA+IN+QRGRDH +P Y +WR+FC + + D
Sbjct: 478 LQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPAD 537
Query: 1128 LSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGD 1187
LS I+ + V DK+ +LY NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD
Sbjct: 538 LSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGD 597
Query: 1188 RFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSM 1247
FW+EN VF Q R++++ SL+R++CDN + + + F + + + SC+ +P M
Sbjct: 598 WFWWENSHVFTDAQRRELEKHSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSIPGM 656
Query: 1248 DLRFWAD 1254
+L W +
Sbjct: 657 NLEAWRE 663
>BC132813-1|AAI32814.1| 515|Homo sapiens peroxidasin homolog
(Drosophila)-like protein.
Length = 515
Score = 522 bits (1288), Expect = e-147
Identities = 243/499 (48%), Positives = 325/499 (65%), Gaps = 4/499 (0%)
Query: 759 MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVPLNDPRVNNRRCID 817
M M WG +L+HDLDH +P +S+ + DG C C PPCFP++ DPR + C+
Sbjct: 1 MLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCML 60
Query: 818 FIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLR 877
F R ++ REQINQ T+++D S VYG + ++ LRD + GLL+
Sbjct: 61 FARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLK 120
Query: 878 VGATFP-GRKPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHN 936
G +P KPLLP S +C R +ES CF+AGD RANE + LAAMHT+W REHN
Sbjct: 121 TGFPWPPSGKPLLPFSTGPPTECARQEQESP--CFLAGDHRANEHLALAAMHTLWFREHN 178
Query: 937 RIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNR 996
R+A +L ALNP W+G+ VYQEARK+VGA++Q ITY HWLP +LG G L Y+ Y+
Sbjct: 179 RVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPN 238
Query: 997 LNPSISNVFATAALRFGHSLINPVLHRYDENFETIPQGHLLLRNAFFSPWRLVDEGGVDP 1056
+N I N FATAA RFGH+LINP+L+R + I +GHL A FSP R++ EGG+DP
Sbjct: 239 VNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDP 298
Query: 1057 LLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQF 1116
+LRG+F AK + L+ ELT++LF +A++ A+D AA IQRGRDH IPPY +R F
Sbjct: 299 VLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVF 358
Query: 1117 CNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLL 1176
CN++ V +F+DL EI D E+R KL++LYGS +ID+W ++ED + G +VGP CL
Sbjct: 359 CNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLF 418
Query: 1177 MEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQD 1236
+ QF RLRDGDRFWYENP VF P QL Q+K+ SL+R+LCDNGD+I + +VF E
Sbjct: 419 VTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQ 478
Query: 1237 GLVSCEDLPSMDLRFWADC 1255
++C ++P +DLR W DC
Sbjct: 479 DYLNCSEIPKVDLRVWQDC 497
>AK131524-1|BAD18663.1| 515|Homo sapiens protein ( Homo sapiens cDNA
FLJ43518 fis, clone PERIC2009086, moderately similar to
Homo sapiens melanoma-associated antigen MG50 mRNA. ).
Length = 515
Score = 522 bits (1288), Expect = e-147
Identities = 243/499 (48%), Positives = 325/499 (65%), Gaps = 4/499 (0%)
Query: 759 MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVPLNDPRVNNRRCID 817
M M WG +L+HDLDH +P +S+ + DG C C PPCFP++ DPR + C+
Sbjct: 1 MLMHWGWFLEHDLDHTVPALSTARFSDGRPCNSVCTNDPPCFPMNTRHADPRGTHAPCML 60
Query: 818 FIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLR 877
F R ++ REQINQ T+++D S VYG + ++ LRD + GLL+
Sbjct: 61 FARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLK 120
Query: 878 VGATFP-GRKPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHN 936
G +P KPLLP S +C R +ES CF+AGD RANE + LAAMHT+W REHN
Sbjct: 121 TGFPWPPSGKPLLPFSTGPPTECARQEQESP--CFLAGDHRANEHLALAAMHTLWFREHN 178
Query: 937 RIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNR 996
R+A +L ALNP W+G+ VYQEARK+VGA++Q ITY HWLP +LG G L Y+ Y+
Sbjct: 179 RVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPN 238
Query: 997 LNPSISNVFATAALRFGHSLINPVLHRYDENFETIPQGHLLLRNAFFSPWRLVDEGGVDP 1056
+N I N FATAA RFGH+LINP+L+R + I +GHL A FSP R++ EGG+DP
Sbjct: 239 VNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDP 298
Query: 1057 LLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQF 1116
+LRG+F AK + L+ ELT++LF +A++ A+D AA IQRGRDH IPPY +R F
Sbjct: 299 VLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVF 358
Query: 1117 CNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLL 1176
CN++ V +F+DL EI D E+R KL++LYGS +ID+W ++ED + G +VGP CL
Sbjct: 359 CNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLF 418
Query: 1177 MEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYLPEVQD 1236
+ QF RLRDGDRFWYENP VF P QL Q+K+ SL+R+LCDNGD+I + +VF E
Sbjct: 419 VTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQ 478
Query: 1237 GLVSCEDLPSMDLRFWADC 1255
++C ++P +DLR W DC
Sbjct: 479 DYLNCSEIPKVDLRVWQDC 497
>M29913-1|AAA58458.1| 715|Homo sapiens eosinophil peroxidase protein.
Length = 715
Score = 510 bits (1257), Expect = e-143
Identities = 274/691 (39%), Positives = 382/691 (55%), Gaps = 26/691 (3%)
Query: 570 LTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLDK 628
+ +A VD A T + + RS + DL + P A R V RAA+ L
Sbjct: 40 IAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGL 99
Query: 629 LKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLDG 688
L+E +Q + + PFN VL+ L ++++ SGC + + CSD KYR++ G
Sbjct: 100 LEEKLQPQR----SGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSD-----KYRTITG 150
Query: 689 SCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXXX 748
CNN P+ G S R L YE+G S P GW + NGF LP R
Sbjct: 151 RCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFP 210
Query: 749 XXXXXXXXXH--MTMQWGQWLDHDLDHALP-PVSSQTWDGVDCKKTCDYAPPCFPIDVPL 805
M MQWGQ++DHDLD + P GVDC++TC PPCFPI +P
Sbjct: 211 NERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPP 270
Query: 806 NDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVAE 864
NDPR+ N+R CI F R + R QIN LTSF+DAS VYG E S++
Sbjct: 271 NDPRIKNQRDCIPFFRSAPSCPQNKN-------RVRNQINALTSFVDASMVYGSEVSLSL 323
Query: 865 DLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQIG 923
LR+ TN GLL + F + LLP + C + CF+AGD R+ E
Sbjct: 324 RLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 383
Query: 924 LAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGP-E 982
LAAMHT++MREHNR+A +L+ LNP W+GD++Y EARK++GA +Q ITY +LP++LG
Sbjct: 384 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 443
Query: 983 GYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFE-TIPQGHLLLRNA 1041
LG Y+ Y + ++P ++NVF T A RFGH+++ P + R D + + P H+ L +A
Sbjct: 444 ARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSA 502
Query: 1042 FFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQR 1101
FF+ WR+V EGG+DP+LRG+ TPAKL L EL ++LF + LDLAA+N+QR
Sbjct: 503 FFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQR 562
Query: 1102 GRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILED 1161
RDH +P Y WR+FC +S+ + LS + ++++ K LYG+ NID+W+G I E
Sbjct: 563 SRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEP 622
Query: 1162 QVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNI 1221
+ G +VGPL CL QF R RDGDRFW++ VF Q + + SL+RI+CDN I
Sbjct: 623 LLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALSRISLSRIICDN-TGI 681
Query: 1222 DTISENVFYLPEVQDGLVSCEDLPSMDLRFW 1252
T+S ++F G V+C +P ++L W
Sbjct: 682 TTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712
>DQ054598-1|AAY43126.1| 715|Homo sapiens eosinophil peroxidase
protein.
Length = 715
Score = 510 bits (1257), Expect = e-143
Identities = 274/691 (39%), Positives = 382/691 (55%), Gaps = 26/691 (3%)
Query: 570 LTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLDK 628
+ +A VD A T + + RS + DL + P A R V RAA+ L
Sbjct: 40 IAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGL 99
Query: 629 LKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLDG 688
L+E +Q + + PFN VL+ L ++++ SGC + + CSD KYR++ G
Sbjct: 100 LEEKLQPQR----SGPFNVTDVLTEPQLRLLSQASGCALRDQAERCSD-----KYRTITG 150
Query: 689 SCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXXX 748
CNN P+ G S R L YE+G S P GW + NGF LP R
Sbjct: 151 RCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFP 210
Query: 749 XXXXXXXXXH--MTMQWGQWLDHDLDHALP-PVSSQTWDGVDCKKTCDYAPPCFPIDVPL 805
M MQWGQ++DHDLD + P GVDC++TC PPCFPI +P
Sbjct: 211 NERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPP 270
Query: 806 NDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVAE 864
NDPR+ N+R CI F R + R QIN LTSF+DAS VYG E S++
Sbjct: 271 NDPRIKNQRDCIPFFRSAPSCPQNKN-------RVRNQINALTSFVDASMVYGSEVSLSL 323
Query: 865 DLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQIG 923
LR+ TN GLL + F + LLP + C + CF+AGD R+ E
Sbjct: 324 RLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 383
Query: 924 LAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGP-E 982
LAAMHT++MREHNR+A +L+ LNP W+GD++Y EARK++GA +Q ITY +LP++LG
Sbjct: 384 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 443
Query: 983 GYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFE-TIPQGHLLLRNA 1041
LG Y+ Y + ++P ++NVF T A RFGH+++ P + R D + + P H+ L +A
Sbjct: 444 ARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSA 502
Query: 1042 FFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQR 1101
FF+ WR+V EGG+DP+LRG+ TPAKL L EL ++LF + LDLAA+N+QR
Sbjct: 503 FFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQR 562
Query: 1102 GRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILED 1161
RDH +P Y WR+FC +S+ + LS + ++++ K LYG+ NID+W+G I E
Sbjct: 563 SRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEP 622
Query: 1162 QVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNI 1221
+ G +VGPL CL QF R RDGDRFW++ VF Q + + SL+RI+CDN I
Sbjct: 623 LLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALSRISLSRIICDN-TGI 681
Query: 1222 DTISENVFYLPEVQDGLVSCEDLPSMDLRFW 1252
T+S ++F G V+C +P ++L W
Sbjct: 682 TTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 712
>X15377-1|CAA33438.1| 745|Homo sapiens protein ( Human gene for the
light and heavy chains of myeloperoxidase. ).
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>X04876-2|CAA28565.1| 745|Homo sapiens prepro-myeloperoxidase
protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>S56200-1|AAB25582.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>M19507-1|AAA59863.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>M17176-1|AAA60346.1| 745|Homo sapiens MPO protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>J02694-1|AAA59896.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>DQ088846-1|AAY68218.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>BC130476-1|AAI30477.1| 745|Homo sapiens myeloperoxidase protein.
Length = 745
Score = 499 bits (1231), Expect = e-140
Identities = 270/695 (38%), Positives = 388/695 (55%), Gaps = 25/695 (3%)
Query: 569 ALTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLD 627
++ +A + VD+A + + + + RS + +L + P A R RAA+ LD
Sbjct: 65 SMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALD 124
Query: 628 KLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLD 687
L+ ++S + PFN VL+ L V+++ SGC C + KYR++
Sbjct: 125 LLERKLRSLWR----RPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ---DKYRTIT 177
Query: 688 GSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXX 747
G CNN P G S F R L YE+GFS P GW +K NGF + AR
Sbjct: 178 GMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRF 237
Query: 748 XXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPPCFPIDVP 804
M MQWGQ LDHDLD P + ++ GV+C+ +C PPCFP+ +P
Sbjct: 238 PTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPPCFPLKIP 297
Query: 805 LNDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVA 863
NDPR+ N+ CI F R + R QIN LTSF+DAS VYG E+ +A
Sbjct: 298 PNDPRIKNQADCIPFFRSCPACPGS-------NITIRNQINALTSFVDASMVYGSEEPLA 350
Query: 864 EDLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQI 922
+LR+++N GLL V F + LLP + C + CF+AGD R++E
Sbjct: 351 RNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMP 410
Query: 923 GLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPE 982
L +MHT+ +REHNR+A +LK+LNP WDG+R+YQEARK+VGA +Q ITY +LP++LGP
Sbjct: 411 ELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPT 470
Query: 983 GYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRN 1040
+ L Y+ Y++ ++P I+NVF T A R+GH+LI P + R D ++ + P + L
Sbjct: 471 AMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSR 529
Query: 1041 AFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQ 1100
FF+ WR+V EGG+DP+LRG+ TPAKL Q E+ E+LF + LDL A+N+Q
Sbjct: 530 VFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQ 589
Query: 1101 RGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILE 1160
R RDH +P Y WR+FC + + L + + ++ KL E YG+ +NID+W+GG+ E
Sbjct: 590 RSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSE 649
Query: 1161 DQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDN 1220
G+VGPL C++ QF +LRDGDRFW+EN VF Q + + + SL RI+CDN
Sbjct: 650 PLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDN-TG 708
Query: 1221 IDTISE-NVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
I T+S+ N+F V+C LP+++L W +
Sbjct: 709 ITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>X14346-1|CAA32530.1| 702|Homo sapiens eosinophil preperoxidase (AA
-127 to 575) protein.
Length = 702
Score = 476 bits (1174), Expect = e-133
Identities = 265/691 (38%), Positives = 373/691 (53%), Gaps = 27/691 (3%)
Query: 570 LTQAMRDVDQAIERTVDQLFKN-RSAVVNIGDLYRMTRFPNAPEREVARAAEIYERTLDK 628
+ +A VD A T + + RS + DL + P A R V RAA+ L
Sbjct: 28 IAEAKLLVDAAYNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVVRAADYMHVALGL 87
Query: 629 LKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYHSKYRSLDG 688
L+E +Q + + PF VL+ L ++++ SGC + + CSD KYR++ G
Sbjct: 88 LEEKLQPQR----SGPFIVTDVLTEPQLRLLSQASGCALRDQAERCSD-----KYRTITG 138
Query: 689 SCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLXXXXXXXXX 748
CNN P+ G S R L YE+G S P GW + NGF LP R
Sbjct: 139 RCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAVSNQIVRFP 198
Query: 749 XXXXXXXXXH--MTMQWGQWLDHDLDHALP-PVSSQTWDGVDCKKTCDYAPPCFPIDVPL 805
M MQWGQ++DHDLD + P GVDC++TC PPCFPI +P
Sbjct: 199 NERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPPCFPIKIPP 258
Query: 806 NDPRVNNRR-CIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTSFLDASQVYGFEKSVAE 864
NDPR+ N+R CI F R + R QIN LTSF+DAS VYG E S++
Sbjct: 259 NDPRIKNQRDCIPFFRSAPSCPQNKN-------RVRNQINALTSFVDASMVYGSEVSLSL 311
Query: 865 DLRDLTNDNGLLRVGATFPGR-KPLLPTSGFNGMDCRRNLEESTRSCFVAGDIRANEQIG 923
LR+ TN GLL + F + LLP + C + CF+AGD R+ E
Sbjct: 312 RLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSTETPK 371
Query: 924 LAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGP-E 982
LAAMHT++MREHNR+A +L+ LNP W+GD++Y EARK++GA +Q ITY +LP++LG
Sbjct: 372 LAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKAR 431
Query: 983 GYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFE-TIPQGHLLLRNA 1041
LG Y+ Y + ++P ++NVF T A RFGH+++ P + R D + + P H+ L +A
Sbjct: 432 ARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLSSA 490
Query: 1042 FFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQR 1101
FF+ WR+V EGG+DP+LRG+ TPAKL L EL ++LF + LDLAA+N+QR
Sbjct: 491 FFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGLDLAALNMQR 550
Query: 1102 GRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILED 1161
RDH +P Y WR+FC +S+ + LS + ++++ K LYG+ NID+W+G I E
Sbjct: 551 SRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNIDIWIGAIAEP 610
Query: 1162 QVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNI 1221
+ G +VGPL CL QF R + + F Q + + SL+RI+CDN I
Sbjct: 611 LLPGARVGPLLACLFENQF-RRAETETGSGGRTRCFHQRQRKALSRISLSRIICDN-TGI 668
Query: 1222 DTISENVFYLPEVQDGLVSCEDLPSMDLRFW 1252
T+S ++F G V+C +P ++L W
Sbjct: 669 TTVSRDIFRANIYPRGFVNCSRIPRLNLSAW 699
>U39573-1|AAC50717.1| 712|Homo sapiens salivary peroxidase protein.
Length = 712
Score = 432 bits (1065), Expect = e-120
Identities = 250/652 (38%), Positives = 344/652 (52%), Gaps = 28/652 (4%)
Query: 613 REVARAAEIYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEK 672
R R +++E +L +L++ K S + L++ LEV GC A
Sbjct: 82 RTAIRNGQVWEESLKRLRQ------KASLTNVTDPSLDLTSLSLEV-----GCGAPAPVV 130
Query: 673 DCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGF 732
C D C S YR++ G CNN P G + R L YE+G S P GW NGF
Sbjct: 131 RC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGF 187
Query: 733 TLPSARLXXXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPP-VSSQTWDGVDCK 789
LP AR + MQWGQ +DHDLD A + S + C
Sbjct: 188 PLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCD 247
Query: 790 KTCDYAPPCFPIDVPLNDPRVNNR-RCIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTS 848
+ C CFPI P NDP+ + +C+ F R L REQIN LTS
Sbjct: 248 EYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSL-----AREQINALTS 302
Query: 849 FLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRK-PLLPTSGFNGMDCRRNLEEST 907
FLDAS VY E S+A LR+L++ GL+ V P LP C +
Sbjct: 303 FLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTAR 362
Query: 908 RSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQ 967
CF+AGD RA+E I LA HT+++REHNR+A +LK LNP WDG+++YQEARK++GA +Q
Sbjct: 363 VPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQ 422
Query: 968 FITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDEN 1027
IT+ +LPI+LG + Y+ Y ++P ISNVF T A RFGH + + R DEN
Sbjct: 423 IITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDEN 481
Query: 1028 FETI-PQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYS 1086
++ P+ L L FF+ WR+V +GG+DPL+RG+ +KL + + EL KLF
Sbjct: 482 YQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQP 541
Query: 1087 AHAV-ALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELY 1145
H + DLAAIN QR RDH P Y WR FC++S+ ++L+ + K + KL LY
Sbjct: 542 THRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLY 601
Query: 1146 GSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQI 1205
G+ NID+W+G I E VE G+VGPL CLL +QF ++RDGDRFW+ENP VF +Q +
Sbjct: 602 GTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSL 661
Query: 1206 KETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWADCES 1257
++ S +R++CDN I + + F+ V C + +DL WA ++
Sbjct: 662 QKMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712
>BC107167-1|AAI07168.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 432 bits (1065), Expect = e-120
Identities = 250/652 (38%), Positives = 344/652 (52%), Gaps = 28/652 (4%)
Query: 613 REVARAAEIYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEK 672
R R +++E +L +L++ K S + L++ LEV GC A
Sbjct: 82 RTAIRNGQVWEESLKRLRQ------KASLTNVTDPSLDLTSLSLEV-----GCGAPAPVV 130
Query: 673 DCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGF 732
C D C S YR++ G CNN P G + R L YE+G S P GW NGF
Sbjct: 131 RC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGF 187
Query: 733 TLPSARLXXXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPP-VSSQTWDGVDCK 789
LP AR + MQWGQ +DHDLD A + S + C
Sbjct: 188 PLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCD 247
Query: 790 KTCDYAPPCFPIDVPLNDPRVNNR-RCIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTS 848
+ C CFPI P NDP+ + +C+ F R L REQIN LTS
Sbjct: 248 EYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSL-----AREQINALTS 302
Query: 849 FLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRK-PLLPTSGFNGMDCRRNLEEST 907
FLDAS VY E S+A LR+L++ GL+ V P LP C +
Sbjct: 303 FLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTAR 362
Query: 908 RSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQ 967
CF+AGD RA+E I LA HT+++REHNR+A +LK LNP WDG+++YQEARK++GA +Q
Sbjct: 363 VPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQ 422
Query: 968 FITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDEN 1027
IT+ +LPI+LG + Y+ Y ++P ISNVF T A RFGH + + R DEN
Sbjct: 423 IITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDEN 481
Query: 1028 FETI-PQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYS 1086
++ P+ L L FF+ WR+V +GG+DPL+RG+ +KL + + EL KLF
Sbjct: 482 YQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQP 541
Query: 1087 AHAV-ALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELY 1145
H + DLAAIN QR RDH P Y WR FC++S+ ++L+ + K + KL LY
Sbjct: 542 THRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLY 601
Query: 1146 GSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQI 1205
G+ NID+W+G I E VE G+VGPL CLL +QF ++RDGDRFW+ENP VF +Q +
Sbjct: 602 GTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSL 661
Query: 1206 KETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWADCES 1257
++ S +R++CDN I + + F+ V C + +DL WA ++
Sbjct: 662 QKMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712
>BC107166-1|AAI07167.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 432 bits (1065), Expect = e-120
Identities = 250/652 (38%), Positives = 344/652 (52%), Gaps = 28/652 (4%)
Query: 613 REVARAAEIYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEK 672
R R +++E +L +L++ K S + L++ LEV GC A
Sbjct: 82 RTAIRNGQVWEESLKRLRQ------KASLTNVTDPSLDLTSLSLEV-----GCGAPAPVV 130
Query: 673 DCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGF 732
C D C S YR++ G CNN P G + R L YE+G S P GW NGF
Sbjct: 131 RC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGF 187
Query: 733 TLPSARLXXXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPP-VSSQTWDGVDCK 789
LP AR + MQWGQ +DHDLD A + S + C
Sbjct: 188 PLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCD 247
Query: 790 KTCDYAPPCFPIDVPLNDPRVNNR-RCIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTS 848
+ C CFPI P NDP+ + +C+ F R L REQIN LTS
Sbjct: 248 EYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSL-----AREQINALTS 302
Query: 849 FLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRK-PLLPTSGFNGMDCRRNLEEST 907
FLDAS VY E S+A LR+L++ GL+ V P LP C +
Sbjct: 303 FLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTAR 362
Query: 908 RSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQ 967
CF+AGD RA+E I LA HT+++REHNR+A +LK LNP WDG+++YQEARK++GA +Q
Sbjct: 363 VPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQ 422
Query: 968 FITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDEN 1027
IT+ +LPI+LG + Y+ Y ++P ISNVF T A RFGH + + R DEN
Sbjct: 423 IITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDEN 481
Query: 1028 FETI-PQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYS 1086
++ P+ L L FF+ WR+V +GG+DPL+RG+ +KL + + EL KLF
Sbjct: 482 YQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQP 541
Query: 1087 AHAV-ALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELY 1145
H + DLAAIN QR RDH P Y WR FC++S+ ++L+ + K + KL LY
Sbjct: 542 THRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLY 601
Query: 1146 GSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQI 1205
G+ NID+W+G I E VE G+VGPL CLL +QF ++RDGDRFW+ENP VF +Q +
Sbjct: 602 GTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSL 661
Query: 1206 KETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWADCES 1257
++ S +R++CDN I + + F+ V C + +DL WA ++
Sbjct: 662 QKMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712
>AY324876-1|AAP72968.1| 712|Homo sapiens lactoperoxidase protein.
Length = 712
Score = 432 bits (1065), Expect = e-120
Identities = 250/652 (38%), Positives = 344/652 (52%), Gaps = 28/652 (4%)
Query: 613 REVARAAEIYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEK 672
R R +++E +L +L++ K S + L++ LEV GC A
Sbjct: 82 RTAIRNGQVWEESLKRLRQ------KASLTNVTDPSLDLTSLSLEV-----GCGAPAPVV 130
Query: 673 DCSDMCYHSKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGF 732
C D C S YR++ G CNN P G + R L YE+G S P GW NGF
Sbjct: 131 RC-DPC--SPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGF 187
Query: 733 TLPSARLXXXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPP-VSSQTWDGVDCK 789
LP AR + MQWGQ +DHDLD A + S + C
Sbjct: 188 PLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCD 247
Query: 790 KTCDYAPPCFPIDVPLNDPRVNNR-RCIDFIRXXXXXXXXXXXXLFGTLQTREQINQLTS 848
+ C CFPI P NDP+ + +C+ F R L REQIN LTS
Sbjct: 248 EYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSL-----AREQINALTS 302
Query: 849 FLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRK-PLLPTSGFNGMDCRRNLEEST 907
FLDAS VY E S+A LR+L++ GL+ V P LP C +
Sbjct: 303 FLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTAR 362
Query: 908 RSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQ 967
CF+AGD RA+E I LA HT+++REHNR+A +LK LNP WDG+++YQEARK++GA +Q
Sbjct: 363 VPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQ 422
Query: 968 FITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDEN 1027
IT+ +LPI+LG + Y+ Y ++P ISNVF T A RFGH + + R DEN
Sbjct: 423 IITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDEN 481
Query: 1028 FETI-PQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYS 1086
++ P+ L L FF+ WR+V +GG+DPL+RG+ +KL + + EL KLF
Sbjct: 482 YQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQP 541
Query: 1087 AHAV-ALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELY 1145
H + DLAAIN QR RDH P Y WR FC++S+ ++L+ + K + KL LY
Sbjct: 542 THRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLY 601
Query: 1146 GSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQI 1205
G+ NID+W+G I E VE G+VGPL CLL +QF ++RDGDRFW+ENP VF +Q +
Sbjct: 602 GTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSL 661
Query: 1206 KETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWADCES 1257
++ S +R++CDN I + + F+ V C + +DL WA ++
Sbjct: 662 QKMSFSRLVCDN-TRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN 712
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 419 bits (1032), Expect = e-116
Identities = 235/640 (36%), Positives = 348/640 (54%), Gaps = 24/640 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+RFN I+EI+PG F L L +LLLN+N ++ + SGAF I+ ID
Sbjct: 63 DLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNEIQSIDR 122
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F+ L LEQLYLH N+I ++P++F +LP+L+RL+LHNN++ + G+F + +++L
Sbjct: 123 QAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESMKRL 182
Query: 127 RLDSNALICDCSILWFIRMLE---NNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQ 183
RLDSN L CDC ILW +L+ + AA C P + G S+A + +L C++P+
Sbjct: 183 RLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELNCERPR 242
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEIFDNGTLMVHEA 242
SEP D +V+ G FTC A G P PEI+WLR++ + + ++R + D+GTLM+
Sbjct: 243 ITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNT 302
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
E D G+++CMAKNVAG+ ++ + SPA P FV PQ + E SV
Sbjct: 303 QETDQGIYQCMAKNVAGEVKTQEVTL------RYFGSPARPTFVIQPQNTEVLVGE-SVT 355
Query: 303 FDCTATGFPKPHVAWYFNGER--MLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+C+ATG P P ++W G+R + ++ R+ + +G + I+NV D+G Y C N
Sbjct: 356 LECSATGHPPPRISW-TRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNID 414
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI-TGN 419
+ A+ + V A P F V P ++ I G V F C+AKG P P I W + L + +
Sbjct: 415 SVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRH 474
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
LVLS + L + V D Y C+A N G + A LT++ + P P D
Sbjct: 475 LVLS--SGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ--PRVTPVFASIPSDTT 530
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+VQ+PC + P +I W KDG ++ E + I+ G L I +V D GRYEC
Sbjct: 531 VEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECV 590
Query: 540 AFNDYGRDTASVFLTVK--DNLLPGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVN 597
A N G + S+ L+V D GD +V ++ +A+ VD+AI T LF +R N
Sbjct: 591 ARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFDSRPRSPN 650
Query: 598 IGDLYRMTRFPNAPER-EVARAAEIYERTLDKLKEYIQSG 636
DL + R+P P E ARA EI+ERTL ++E++Q G
Sbjct: 651 --DLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHG 688
>AK058200-1|BAB71713.1| 494|Homo sapiens protein ( Homo sapiens cDNA
FLJ25471 fis, clone TST09553. ).
Length = 494
Score = 396 bits (976), Expect = e-109
Identities = 174/329 (52%), Positives = 231/329 (70%)
Query: 927 MHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPEGYDQ 986
MHT+W REHNR+A +L ALNP W+G+ VYQEARK+VGA++Q ITY HWLP +LG G
Sbjct: 1 MHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRM 60
Query: 987 LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETIPQGHLLLRNAFFSPW 1046
L Y+ Y+ +N I N FATAA RFGH+LINP+L+R + I +GHL A FSP
Sbjct: 61 LRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPS 120
Query: 1047 RLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHA 1106
R++ EGG+DP+LRG+F AK + L+ ELT++LF +A++ A+D AA IQRGRDH
Sbjct: 121 RIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHG 180
Query: 1107 IPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGG 1166
IPPY +R FCN++ V +F+DL EI D E+R KL++LYGS +ID+W ++ED + G
Sbjct: 181 IPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGT 240
Query: 1167 KVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISE 1226
+VGP CL + QF RLRDGDRFWYENP VF P QL Q+K+ SL+R+LCDNGD+I +
Sbjct: 241 RVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQA 300
Query: 1227 NVFYLPEVQDGLVSCEDLPSMDLRFWADC 1255
+VF E ++C ++P +DLR W DC
Sbjct: 301 DVFVKAEYPQDYLNCSEIPKVDLRVWQDC 329
>X17358-1|CAA35235.1| 876|Homo sapiens protein ( Human mRNA from
alternatively spliced TPO-2 gene for thyroid peroxidase
(EC.1.11.1.7). ).
Length = 876
Score = 359 bits (882), Expect = 5e-98
Identities = 200/505 (39%), Positives = 271/505 (53%), Gaps = 18/505 (3%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPSACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRATEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEG 1052
+ P L L AFFSPW L+ G
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGG 533
Score = 123 bits (297), Expect = 4e-27
Identities = 54/145 (37%), Positives = 87/145 (60%), Gaps = 1/145 (0%)
Query: 1110 YTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVG 1169
Y +WR+FC + + DLS I+ + V DK+ +LY NIDVW+GG+ E+ + + G
Sbjct: 534 YNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTG 593
Query: 1170 PLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVF 1229
PLF CL+ +Q LRDGD FW+EN VF Q R++++ SL+R++CDN + + + F
Sbjct: 594 PLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDN-TGLTRVPMDAF 652
Query: 1230 YLPEVQDGLVSCEDLPSMDLRFWAD 1254
+ + + SC+ + M+L W +
Sbjct: 653 QVGKFPEDFESCDSITGMNLEAWRE 677
>J02970-1|AAA61216.1| 876|Homo sapiens TPO protein.
Length = 876
Score = 357 bits (878), Expect = 1e-97
Identities = 200/505 (39%), Positives = 271/505 (53%), Gaps = 18/505 (3%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTWDG-VDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
Query: 798 CFPIDVPLNDPRVNNRRCIDFIRXXXXXXXXXXXXLFGTLQT---REQINQLTSFLDASQ 854
CFPI +P C+ F R LFG L T R+Q+N LTSFLDAS
Sbjct: 269 CFPIQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
Query: 855 VYGFEKSVAEDLRDLTNDNGLLRVGATF--PGRK--PLLPTSGFNGMDCRRNLEESTRS- 909
VYG ++ LR+ T+ GLLRV A GR P +P + TR
Sbjct: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRRPAACAPEPGIPGETRGP 388
Query: 910 CFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFI 969
CF+AGD RA+E L A+HT+W+REHNR+A LKALN W D VYQEARKVVGA Q I
Sbjct: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
Query: 970 TYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYDENF 1028
T ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R D +F
Sbjct: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
Query: 1029 ETIPQ-GHLLLRNAFFSPWRLVDEG 1052
+ P L L AFFSPW L+ G
Sbjct: 509 QEHPDLPGLWLHQAFFSPWTLLRGG 533
Score = 126 bits (305), Expect = 4e-28
Identities = 55/145 (37%), Positives = 88/145 (60%), Gaps = 1/145 (0%)
Query: 1110 YTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVG 1169
Y +WR+FC + + DLS I+ + V DK+ +LY NIDVW+GG+ E+ + + G
Sbjct: 534 YNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTG 593
Query: 1170 PLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVF 1229
PLF CL+ +Q LRDGD FW+EN VF Q R++++ SL+R++CDN + + + F
Sbjct: 594 PLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDN-TGLTRVPMDAF 652
Query: 1230 YLPEVQDGLVSCEDLPSMDLRFWAD 1254
+ + + SC+ +P M+L W +
Sbjct: 653 QVGKFPEDFESCDSIPGMNLEAWRE 677
>M58151-1|AAA63213.1| 324|Homo sapiens lactoperoxidase protein.
Length = 324
Score = 294 bits (722), Expect = 1e-78
Identities = 141/326 (43%), Positives = 200/326 (61%), Gaps = 4/326 (1%)
Query: 934 EHNRIALQLKALNPFWDGDRVYQEARKVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQY 993
EHNR+A +LK LNP WDG+++YQEARK++GA MQ IT+ +LPI+LG + Y+ Y
Sbjct: 1 EHNRLARELKRLNPQWDGEKLYQEARKILGAFMQIITFRDYLPILLGDHMQKWIPPYQGY 60
Query: 994 DNRLNPSISNVFATAALRFGHSLINPVLHRYDENFETI-PQGHLLLRNAFFSPWRLVDEG 1052
++P ISNVF T A RFGH + + R DEN++ P+ L L FF+ WR+V +G
Sbjct: 61 SESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDG 119
Query: 1053 GVDPLLRGMFTTPAKLKTSKQNLNSELTEKLFYSAHAV-ALDLAAINIQRGRDHAIPPYT 1111
G+DPL+RG+ +KL + + EL KLF H + DLAAIN QR RDH P Y
Sbjct: 120 GIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYN 179
Query: 1112 KWRQFCNMSEVNDFDDLSGEISDKEVRDKLQELYGSVHNIDVWVGGILEDQVEGGKVGPL 1171
WR FC++S+ ++L+ + K + KL LYG+ NID+W+G I E VE G+VGPL
Sbjct: 180 SWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPL 239
Query: 1172 FRCLLMEQFVRLRDGDRFWYENPSVFKPDQLRQIKETSLARILCDNGDNIDTISENVFYL 1231
CLL +QF ++RDGDRFW+ENP VF +Q +++ S +R++CDN I + + F+
Sbjct: 240 LACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDN-TRITKVPRDPFWA 298
Query: 1232 PEVQDGLVSCEDLPSMDLRFWADCES 1257
V C + +DL WA ++
Sbjct: 299 NSYPYDFVDCSAIDKLDLSPWASVKN 324
>AF439430-1|AAL74416.1| 760|Homo sapiens thyroid peroxidase protein.
Length = 760
Score = 281 bits (689), Expect = 1e-74
Identities = 129/291 (44%), Positives = 191/291 (65%), Gaps = 3/291 (1%)
Query: 966 MQFITYEHWLPIILGPEGYDQ-LGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRY 1024
+Q IT ++P ILGPE + Q +G Y+ YD+ NP++SNVF+TAA RFGH+ I+P++ R
Sbjct: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
Query: 1025 DENFETIPQ-GHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKL 1083
D +F+ P L L AFFSPW L+ GG+DPL+RG+ PAKL+ Q +N ELTE+L
Sbjct: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
Query: 1084 FYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQE 1143
F +++ LDLA+IN+QRGRDH +P Y +WR+FC + + DLS I+ + V DK+ +
Sbjct: 392 FVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 451
Query: 1144 LYGSVHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGDRFWYENPSVFKPDQLR 1203
LY NIDVW+GG+ E+ + + GPLF CL+ +Q LRDGD FW+EN VF Q R
Sbjct: 452 LYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRR 511
Query: 1204 QIKETSLARILCDNGDNIDTISENVFYLPEVQDGLVSCEDLPSMDLRFWAD 1254
++++ SL+R++CDN + + + F + + + SC+ +P M+L W +
Sbjct: 512 ELEKHSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSIPGMNLEAWRE 561
Score = 153 bits (371), Expect = 4e-36
Identities = 82/246 (33%), Positives = 122/246 (49%), Gaps = 8/246 (3%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 34 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 92
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 93 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGSDCQMTCENQNP 268
Query: 798 CFPIDV 803
CFPI +
Sbjct: 269 CFPIQI 274
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 178 bits (433), Expect = 1e-43
Identities = 122/388 (31%), Positives = 185/388 (47%), Gaps = 27/388 (6%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P +V V+ GE AV CV G P P + W +D + E R I G LM+
Sbjct: 168 FRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITI-RGGKLMMSHT 226
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G++ C+A N+AG+ S A+++V + P F+ P + + + V
Sbjct: 227 LKSDAGMYVCVASNMAGERESAAAEVMVLER---------PSFLRRPVNQVV-LADAPVT 276
Query: 303 FDCTATGFPKPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
F C G P P + W +GE L R ++ + S+ I +V D G YTC EN G+
Sbjct: 277 FLCEVKGDPPPRLRWRKEDGE--LPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGR 334
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPI-- 416
AS L V PP + P +Q A G++V F C+ KG P P+I W + ++ P
Sbjct: 335 AEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQS 394
Query: 417 ---TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEI--IPPRI 471
TG +S Q L + V R D Y C+A + G I A A+L ++ + +PP I
Sbjct: 395 LQPTGRFSVSPRGQ-LNITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDGLPPVI 453
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD-RISITVIGSLIIRNVSV 530
+ P + +SV +PC + P S+ W+KDG + DD + G+L I NV
Sbjct: 454 LQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQE 513
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKDN 558
D G Y C A + G T S +L ++++
Sbjct: 514 MDMGFYSCVAKSSTGEATWSGWLKMRED 541
Score = 173 bits (422), Expect = 3e-42
Identities = 122/399 (30%), Positives = 190/399 (47%), Gaps = 32/399 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD-SEVIPLNEN---RYEIFDNGTL 237
P+ +P D+ VS GE A C A G P P I W ++ + V + E+ + +G L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 238 ----MVHEANEN-DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKR 292
+VH D+G++ C+A+N G A S+ A + V ++ F +P
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDD--------FRQSPGNV 175
Query: 293 FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYT 352
+ E +V+ G P+P V+W +G R+ E I G +++ + SDAG+Y
Sbjct: 176 VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYV 235
Query: 353 CQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
C N+ G + SA+ + V PSF+ P NQ + V F C+ KG P P ++W +
Sbjct: 236 CVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKED 295
Query: 412 VILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
LP TG + D+ +L + V+ +D+ Y C AEN G EAS L++ +PP++
Sbjct: 296 GELP-TGRYEIRSDH-SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH----VPPQL 349
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDDRISITVIGSL 523
V +P+D A SV CE + PP +I W+K+GS+++ R S++ G L
Sbjct: 350 VTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQL 409
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPG 562
I V D G Y C A + G A L +K L G
Sbjct: 410 NITAVQRGDAGYYMCQAVSVAGSILAKALLEIKGASLDG 448
Score = 127 bits (307), Expect = 2e-28
Identities = 84/298 (28%), Positives = 130/298 (43%), Gaps = 27/298 (9%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P + V F C G+P P + W ++ +P RYEI + +L +
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELP--TGRYEIRSDHSLWI 313
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D+G + C+A+N G+A + + + H PP V+ PQ + A E
Sbjct: 314 GHVSAEDEGTYTCVAENSVGRAEASGSLSV-------H---VPPQLVTQPQDQMAAPGE- 362
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
SV F C G P P + W G ++LL R + G + I VQ DAG Y
Sbjct: 363 SVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYY 422
Query: 352 TCQVENIHGKISASVPLEVTA------PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ ++ G I A LE+ PP + P NQT ++G +VW C+ G P+PS+
Sbjct: 423 MCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSV 482
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+W ++ L + N L + V D Y C A++ G S L + +
Sbjct: 483 RWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRE 540
Score = 85.0 bits (201), Expect = 2e-15
Identities = 94/370 (25%), Positives = 147/370 (39%), Gaps = 36/370 (9%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-------NENRYEIFDN 234
PQ ++P D + GE+ F C G P P I W ++ + L R+ +
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + D G + C A +VAG S AK ++ K PPV + P +
Sbjct: 407 GQLNITAVQRGDAGYYMCQAVSVAG---SILAKALLEIKGAS-LDGLPPVILQGPANQTL 462
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTC 353
+ +SV C TG P+P V W +G+ + ++ + NG++ I NVQ D G Y+C
Sbjct: 463 VLG-SSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSC 521
Query: 354 QVENIHGK--------------ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
++ G+ +S P E ++PP P T I +++ T K
Sbjct: 522 VAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPV-VTEITKNSITLTWKPNP 580
Query: 400 TPKPSIKWYRNTVILPITGNL--VLSDDNQNLTLLEVTRDDDAIY--HCRAENDGGMIEA 455
++ Y P GN ++D Q T + IY RA G+ E
Sbjct: 581 QTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEP 640
Query: 456 SAVL-TLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVP-PASIDWRKDGS-RIVE 511
S V + + P R V P E +V++ I P + W DG ++V+
Sbjct: 641 SPVSEPVRTQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWTVDGPVQLVQ 700
Query: 512 DDRISITVIG 521
R+S V G
Sbjct: 701 GFRVSWRVAG 710
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/200 (29%), Positives = 93/200 (46%), Gaps = 23/200 (11%)
Query: 372 APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL------PITGNLVLSDD 425
A P + P + G+ C+A+G P+P+I+WY+N + P L+L
Sbjct: 62 AMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSG 121
Query: 426 N---QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ R D+ +Y C A N G AS +LE V ++ P ++
Sbjct: 122 ALFFPRIVHGRRARPDEGVYTCVARNYLG-AAASRNASLE-VAVLRDDFRQSPGNV---- 175
Query: 483 ETSVQMPCEIESVPP-----ASIDWRKDGSRIVEDD-RISITVIGSLIIRNVSVTDTGRY 536
+V P +E VPP S+ WRKDG+R+ E++ RI+I G L++ + +D G Y
Sbjct: 176 VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRG-GKLMMSHTLKSDAGMY 234
Query: 537 ECSAFNDYG-RDTASVFLTV 555
C A N G R++A+ + V
Sbjct: 235 VCVASNMAGERESAAAEVMV 254
Score = 54.8 bits (126), Expect = 2e-06
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 163 SVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI 222
S+ +L +K L P P + + G + C TG P P + W +D + +
Sbjct: 432 SILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL 491
Query: 223 PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
++ +++ NGTL + E D G + C+AK+ G+A ++ + + SP P
Sbjct: 492 QGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEA---TWSGWLKMREDWGVSPDP 548
Query: 283 PVFVSTP 289
P S+P
Sbjct: 549 PTEPSSP 555
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 177 bits (432), Expect = 2e-43
Identities = 122/388 (31%), Positives = 185/388 (47%), Gaps = 27/388 (6%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P +V V+ GE AV CV G P P + W +D + E R I G LM+
Sbjct: 168 FRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITI-RGGKLMMSHT 226
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G++ C+A N+AG+ S A+++V + P F+ P + + + V
Sbjct: 227 LKSDAGMYVCVASNMAGERESAAAEVMVLER---------PSFLRRPVNQVV-LADAPVT 276
Query: 303 FDCTATGFPKPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
F C G P P + W +GE L R ++ + S+ I +V D G YTC EN G+
Sbjct: 277 FLCEVKGDPPPRLRWRKEDGE--LPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGR 334
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPI-- 416
AS L V PP + P +Q A G++V F C+ KG P P+I W + ++ P
Sbjct: 335 AEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQS 394
Query: 417 ---TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEI--IPPRI 471
TG +S Q L + V R D Y C+A + G I A A+L ++ + +PP I
Sbjct: 395 LQPTGRFSVSPRGQ-LNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVI 453
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD-RISITVIGSLIIRNVSV 530
+ P + +SV +PC + P S+ W+KDG + DD + G+L I NV
Sbjct: 454 LQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQE 513
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKDN 558
D G Y C A + G T S +L ++++
Sbjct: 514 MDMGFYSCVAKSSTGEATWSGWLKMRED 541
Score = 173 bits (422), Expect = 3e-42
Identities = 122/399 (30%), Positives = 190/399 (47%), Gaps = 32/399 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD-SEVIPLNEN---RYEIFDNGTL 237
P+ +P D+ VS GE A C A G P P I W ++ + V + E+ + +G L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 238 ----MVHEANEN-DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKR 292
+VH D+G++ C+A+N G A S+ A + V ++ F +P
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDD--------FRQSPGNV 175
Query: 293 FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYT 352
+ E +V+ G P+P V+W +G R+ E I G +++ + SDAG+Y
Sbjct: 176 VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYV 235
Query: 353 CQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
C N+ G + SA+ + V PSF+ P NQ + V F C+ KG P P ++W +
Sbjct: 236 CVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKED 295
Query: 412 VILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
LP TG + D+ +L + V+ +D+ Y C AEN G EAS L++ +PP++
Sbjct: 296 GELP-TGRYEIRSDH-SLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVH----VPPQL 349
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDDRISITVIGSL 523
V +P+D A SV CE + PP +I W+K+GS+++ R S++ G L
Sbjct: 350 VTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQL 409
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPG 562
I V D G Y C A + G A L +K L G
Sbjct: 410 NITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDG 448
Score = 128 bits (308), Expect = 2e-28
Identities = 84/298 (28%), Positives = 130/298 (43%), Gaps = 27/298 (9%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P + V F C G+P P + W ++ +P RYEI + +L +
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELP--TGRYEIRSDHSLWI 313
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D+G + C+A+N G+A + + + H PP V+ PQ + A E
Sbjct: 314 GHVSAEDEGTYTCVAENSVGRAEASGSLSV-------H---VPPQLVTQPQDQMAAPGE- 362
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
SV F C G P P + W G ++LL R + G + I VQ DAG Y
Sbjct: 363 SVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYY 422
Query: 352 TCQVENIHGKISASVPLEVTA------PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ ++ G I A LE+ PP + P NQT ++G +VW C+ G P+PS+
Sbjct: 423 VCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSV 482
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+W ++ L + N L + V D Y C A++ G S L + +
Sbjct: 483 RWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRE 540
Score = 85.0 bits (201), Expect = 2e-15
Identities = 94/370 (25%), Positives = 147/370 (39%), Gaps = 36/370 (9%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-------NENRYEIFDN 234
PQ ++P D + GE+ F C G P P I W ++ + L R+ +
Sbjct: 347 PQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPR 406
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + D G + C A +VAG S AK ++ K PPV + P +
Sbjct: 407 GQLNITAVQRGDAGYYVCQAVSVAG---SILAKALLEIKGAS-LDGLPPVILQGPANQTL 462
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTC 353
+ +SV C TG P+P V W +G+ + ++ + NG++ I NVQ D G Y+C
Sbjct: 463 VLG-SSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSC 521
Query: 354 QVENIHGK--------------ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
++ G+ +S P E ++PP P T I +++ T K
Sbjct: 522 VAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPV-VTEITKNSITLTWKPNP 580
Query: 400 TPKPSIKWYRNTVILPITGNL--VLSDDNQNLTLLEVTRDDDAIY--HCRAENDGGMIEA 455
++ Y P GN ++D Q T + IY RA G+ E
Sbjct: 581 QTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEP 640
Query: 456 SAVL-TLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVP-PASIDWRKDGS-RIVE 511
S V + + P R V P E +V++ I P + W DG ++V+
Sbjct: 641 SPVSEPVRTQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWTVDGPVQLVQ 700
Query: 512 DDRISITVIG 521
R+S V G
Sbjct: 701 GFRVSWRVAG 710
Score = 61.7 bits (143), Expect = 2e-08
Identities = 58/200 (29%), Positives = 93/200 (46%), Gaps = 23/200 (11%)
Query: 372 APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL------PITGNLVLSDD 425
A P + P + G+ C+A+G P+P+I+WY+N + P L+L
Sbjct: 62 AMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSG 121
Query: 426 N---QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ R D+ +Y C A N G AS +LE V ++ P ++
Sbjct: 122 ALFFPRIVHGRRARPDEGVYTCVARNYLG-AAASRNASLE-VAVLRDDFRQSPGNV---- 175
Query: 483 ETSVQMPCEIESVPP-----ASIDWRKDGSRIVEDD-RISITVIGSLIIRNVSVTDTGRY 536
+V P +E VPP S+ WRKDG+R+ E++ RI+I G L++ + +D G Y
Sbjct: 176 VVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRG-GKLMMSHTLKSDAGMY 234
Query: 537 ECSAFNDYG-RDTASVFLTV 555
C A N G R++A+ + V
Sbjct: 235 VCVASNMAGERESAAAEVMV 254
Score = 54.8 bits (126), Expect = 2e-06
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
Query: 163 SVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI 222
S+ +L +K L P P + + G + C TG P P + W +D + +
Sbjct: 432 SILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWL 491
Query: 223 PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
++ +++ NGTL + E D G + C+AK+ G+A ++ + + SP P
Sbjct: 492 QGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEA---TWSGWLKMREDWGVSPDP 548
Query: 283 PVFVSTP 289
P S+P
Sbjct: 549 PTEPSSP 555
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 176 bits (429), Expect = 4e-43
Identities = 128/475 (26%), Positives = 206/475 (43%), Gaps = 33/475 (6%)
Query: 10 FNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDV- 68
FN + ++ L L L L+ N + + GAF G I D
Sbjct: 316 FNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTS 375
Query: 69 --FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F L L +L L N+I + FS L L+ L L N ++S+ + +F M L++L
Sbjct: 376 GAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKEL 435
Query: 127 RLDSNALICDCSILWFIRMLENNEWM-HVAATCYQPASVTGTSLAAMKHHDLPCQ---QP 182
+ S++ +CDC + W L V ATC P S+ G S+ ++ C +P
Sbjct: 436 HISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLKP 495
Query: 183 QFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENRYEI 231
Q ++P G++ FTC A+ +P W +D+EV+ ++ E+
Sbjct: 496 QIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEV 555
Query: 232 FDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ 290
+ T++ + + +G ++C+ N G +S A++ V P F TP
Sbjct: 556 MEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---------VLPSFTKTPH 606
Query: 291 KRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNVQNS 346
+ T +C ATG P P +AW +G + ER ++ + I +V+
Sbjct: 607 DITIRTT-TMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKID 665
Query: 347 DAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIK 406
DAGVY+C +N G ISA+ L V PS +V ++ +G+ V CKA G P P I
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRIT 725
Query: 407 WYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
W++ L +T L+ DNQ L + V +D Y C N G A + L++
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 84.6 bits (200), Expect = 2e-15
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 9/230 (3%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V G Y C + N G S L V PSF P + T
Sbjct: 555 VMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTT 614
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + D+ + +V DD +Y C A
Sbjct: 615 MARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTA 674
Query: 447 ENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDG 506
+N G I A+A LT+ + P +V+ ED +V + C+ PP I W K
Sbjct: 675 QNSAGSISANATLTVLET----PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGD 730
Query: 507 SRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +R +T L +++NV D GRY C N G + A L+V
Sbjct: 731 RPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E+ F H ++ L L N + L GAF G I +
Sbjct: 145 DLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLP 204
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
F+ L L QL L+ N I IE TF L L+ L L N + + G+F G+ K+
Sbjct: 205 VRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHV 263
Query: 126 LRLDSNALI 134
L L+ N+L+
Sbjct: 264 LHLEYNSLV 272
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/123 (27%), Positives = 55/123 (44%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I ++ G F L ++ L L N L + SG+ +G I I +
Sbjct: 245 NNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWS 304
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ E+ + L L L L +N + I G+F+G+ LR L LD
Sbjct: 305 FCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDH 364
Query: 131 NAL 133
N +
Sbjct: 365 NEI 367
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 4/129 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRS-GAFHGXXXXXXXXXXXXXIKHID 65
++ +N + EI+P F L L+ + LN+N L A+ S GA I+ ++
Sbjct: 74 NLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGA--ASSHVVSLFLQHNKIRSVE 131
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LR 124
+ LE L L +N I + F + P + L L N++ ++ G+F G+ + L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 125 KLRLDSNAL 133
LRL N +
Sbjct: 192 TLRLSKNRI 200
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/127 (29%), Positives = 53/127 (41%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N I+ IE F L+ L L L N++ L GAF G + ++S
Sbjct: 217 DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNS 276
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
L L QL+L N I I + +S +L L L N L + S + L L
Sbjct: 277 GSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVL 336
Query: 127 RLDSNAL 133
RL N++
Sbjct: 337 RLSHNSI 343
Score = 37.9 bits (84), Expect = 0.24
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 78 LYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIP 113
L L N++ I+P F +LP L +YL+NN+L ++P
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVP 108
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 176 bits (428), Expect = 5e-43
Identities = 128/475 (26%), Positives = 206/475 (43%), Gaps = 33/475 (6%)
Query: 10 FNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDV- 68
FN + ++ L L L L+ N + + GAF G I D
Sbjct: 316 FNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTS 375
Query: 69 --FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
F L L +L L N+I + FS L L+ L L N ++S+ + +F M L++L
Sbjct: 376 GAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKEL 435
Query: 127 RLDSNALICDCSILWFIRMLENNEWM-HVAATCYQPASVTGTSLAAMKHHDLPCQ---QP 182
+ S++ +CDC + W L V ATC P S+ G S+ ++ C +P
Sbjct: 436 HISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLKP 495
Query: 183 QFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENRYEI 231
Q ++P G++ FTC A+ +P W +D+EV+ ++ E+
Sbjct: 496 QIITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEV 555
Query: 232 FDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ 290
+ T++ + + +G ++C+ N G +S A++ V P F TP
Sbjct: 556 MEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---------VLPSFTKTPH 606
Query: 291 KRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNVQNS 346
+ T +C ATG P P +AW +G + ER ++ + I +V+
Sbjct: 607 DITIRTT-TVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKID 665
Query: 347 DAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIK 406
DAGVY+C +N G ISA+ L V PS +V ++ +G+ V CKA G P P I
Sbjct: 666 DAGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRIT 725
Query: 407 WYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
W++ L +T L+ DNQ L + V +D Y C N G A + L++
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 84.2 bits (199), Expect = 3e-15
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 9/230 (3%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V G Y C + N G S L V PSF P + T
Sbjct: 555 VMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTT 614
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + D+ + +V DD +Y C A
Sbjct: 615 VARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTA 674
Query: 447 ENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDG 506
+N G I A+A LT+ + P +V+ ED +V + C+ PP I W K
Sbjct: 675 QNSAGSISANATLTVLET----PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGD 730
Query: 507 SRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +R +T L +++NV D GRY C N G + A L+V
Sbjct: 731 RPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E+ F H ++ L L N + L GAF G I +
Sbjct: 145 DLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLP 204
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
F+ L L QL L+ N I IE TF L L+ L L N + + G+F G+ K+
Sbjct: 205 VRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHV 263
Query: 126 LRLDSNALI 134
L L+ N+L+
Sbjct: 264 LHLEYNSLV 272
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/123 (27%), Positives = 55/123 (44%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I ++ G F L ++ L L N L + SG+ +G I I +
Sbjct: 245 NNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWS 304
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ E+ + L L L L +N + I G+F+G+ LR L LD
Sbjct: 305 FCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDH 364
Query: 131 NAL 133
N +
Sbjct: 365 NEI 367
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 4/129 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRS-GAFHGXXXXXXXXXXXXXIKHID 65
++ +N + EI+P F L L+ + LN+N L A+ S GA I+ ++
Sbjct: 74 NLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGA--ASSHVVSLFLQHNKIRSVE 131
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LR 124
+ LE L L +N I + F + P + L L N++ ++ G+F G+ + L
Sbjct: 132 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 191
Query: 125 KLRLDSNAL 133
LRL N +
Sbjct: 192 TLRLSKNRI 200
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/127 (29%), Positives = 53/127 (41%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N I+ IE F L+ L L L N++ L GAF G + ++S
Sbjct: 217 DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNS 276
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
L L QL+L N I I + +S +L L L N L + S + L L
Sbjct: 277 GSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVL 336
Query: 127 RLDSNAL 133
RL N++
Sbjct: 337 RLSHNSI 343
Score = 37.9 bits (84), Expect = 0.24
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 78 LYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIP 113
L L N++ I+P F +LP L +YL+NN+L ++P
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVP 108
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 175 bits (425), Expect = 1e-42
Identities = 129/474 (27%), Positives = 208/474 (43%), Gaps = 33/474 (6%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I I ++ +L L+L+ N+L L + I HI F+
Sbjct: 317 NSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFK 376
Query: 71 DLKHLEQLYLHVNEIHHIEPET---FSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLR 127
L+ L L L NEI +T FS L L +L L N ++S+ + +F M L++L
Sbjct: 377 GLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLNLGGNAIRSVQFDAFVKMKNLKELH 436
Query: 128 LDSNALICDCSILWFIRMLENNEWM-HVAATCYQPASVTGTSLAAMKHHDLPCQ---QPQ 183
+ S++ +CDC + W L V ATC P S+ G S+ ++ C +PQ
Sbjct: 437 ISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPESLKGQSIFSVPPESFVCDDFLKPQ 496
Query: 184 FESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENRYEIF 232
++P G++ FTC A+ +P W +D+EV+ ++ E+
Sbjct: 497 IITQPETTMAMVGKDIRFTCSAASSSSSPMTFAWKKDNEVLTNADMENFVHVHAQDGEVM 556
Query: 233 DNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQK 291
+ T++ + + +G ++C+ N G +S A++ V P F TP
Sbjct: 557 EYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN---------VLPSFTKTPHD 607
Query: 292 RFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNVQNSD 347
+ T +C ATG P P +AW +G + ER ++ + I +V+ D
Sbjct: 608 ITIRTT-TVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDD 666
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
AGVY+C +N G ISA+ L V PS +V ++ +G+ V CKA G P P I W
Sbjct: 667 AGVYSCTAQNSAGSISANATLTVLETPSLVVPLEDRVVSVGETVALQCKATGNPPPRITW 726
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
++ L +T L+ DNQ L + V +D Y C N G A + L++
Sbjct: 727 FKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 84.2 bits (199), Expect = 3e-15
Identities = 62/230 (26%), Positives = 96/230 (41%), Gaps = 9/230 (3%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V G Y C + N G S L V PSF P + T
Sbjct: 555 VMEYTTILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTT 614
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + D+ + +V DD +Y C A
Sbjct: 615 VARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTA 674
Query: 447 ENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDG 506
+N G I A+A LT+ + P +V+ ED +V + C+ PP I W K
Sbjct: 675 QNSAGSISANATLTVLET----PSLVVPLEDRVVSVGETVALQCKATGNPPPRITWFKGD 730
Query: 507 SRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +R +T L +++NV D GRY C N G + A L+V
Sbjct: 731 RPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSV 780
Score = 55.6 bits (128), Expect = 1e-06
Identities = 40/129 (31%), Positives = 57/129 (44%), Gaps = 2/129 (1%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E+ F H ++ L L N + L GAF G I +
Sbjct: 169 DLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLP 228
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
F+ L L QL L+ N I IE TF L L+ L L N + + G+F G+ K+
Sbjct: 229 VRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHV 287
Query: 126 LRLDSNALI 134
L L+ N+L+
Sbjct: 288 LHLEYNSLV 296
Score = 53.6 bits (123), Expect = 5e-06
Identities = 34/123 (27%), Positives = 55/123 (44%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I ++ G F L ++ L L N L + SG+ +G I I +
Sbjct: 269 NNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWS 328
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ E+ + L L L L +N + I G+F+G+ LR L LD
Sbjct: 329 FCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDH 388
Query: 131 NAL 133
N +
Sbjct: 389 NEI 391
Score = 50.4 bits (115), Expect = 4e-05
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 4/129 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRS-GAFHGXXXXXXXXXXXXXIKHID 65
++ +N + EI+P F L L+ + LN+N L A+ S GA I+ ++
Sbjct: 98 NLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGA--ASSHVVSLFLQHNKIRSVE 155
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LR 124
+ LE L L +N I + F + P + L L N++ ++ G+F G+ + L
Sbjct: 156 GSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLL 215
Query: 125 KLRLDSNAL 133
LRL N +
Sbjct: 216 TLRLSKNRI 224
Score = 49.6 bits (113), Expect = 7e-05
Identities = 20/53 (37%), Positives = 35/53 (66%)
Query: 61 IKHIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIP 113
+ ID F+DL +L+++ L N++ I+P F +LP L +YL+NN+L ++P
Sbjct: 80 LSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVP 132
Score = 49.2 bits (112), Expect = 1e-04
Identities = 37/127 (29%), Positives = 53/127 (41%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N I+ IE F L+ L L L N++ L GAF G + ++S
Sbjct: 241 DLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNS 300
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKL 126
L L QL+L N I I + +S +L L L N L + S + L L
Sbjct: 301 GSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVL 360
Query: 127 RLDSNAL 133
RL N++
Sbjct: 361 RLSHNSI 367
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/56 (35%), Positives = 32/56 (57%)
Query: 78 LYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDSNAL 133
L L N++ I+P F +LP L + L NKL I F+ +P L+++ L++N L
Sbjct: 73 LNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNEL 128
Score = 39.5 bits (88), Expect = 0.079
Identities = 27/104 (25%), Positives = 46/104 (44%), Gaps = 1/104 (0%)
Query: 28 RSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQDLKHLEQLYLHVNEIHH 87
RSL L+ N L + F + ID F+DL +L+++YL+ NE+
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTA 130
Query: 88 IEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDSN 131
+ P + + L+L +NK++S+ + L L L N
Sbjct: 131 V-PSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLN 173
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 172 bits (419), Expect = 6e-42
Identities = 122/389 (31%), Positives = 176/389 (45%), Gaps = 23/389 (5%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P+DV V+ GE AV C G P P I W +D + + R I G LM+
Sbjct: 172 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYT 230
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G + C+ N+ G+ S+ A++ V + P FV P +++ S
Sbjct: 231 RKSDAGKYVCVGTNMVGERESEVAELTVLER---------PSFVKRPSNLAVTVDD-SAE 280
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C A G P P V W + L R ++ + ++ I+ V D G YTC EN+ GK
Sbjct: 281 FKCEARGDPVPTVRWR-KDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 339
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR----NTVIL---P 415
AS L V PP F+V P +Q +G V F C+A G P+P+I W R N + P
Sbjct: 340 EASATLTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPP 399
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPRIVL 473
+ + +LT+ V R D Y C+ N G I A L + V + PP I
Sbjct: 400 QSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQ 459
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVSVTD 532
P + + + + C P +I WRKDG + +D RI G L IR + D
Sbjct: 460 GPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGD 519
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
TGRY C A G T S ++ V++ +P
Sbjct: 520 TGRYTCIASTPSGEATWSAYIEVQEFGVP 548
Score = 171 bits (415), Expect = 2e-41
Identities = 121/410 (29%), Positives = 190/410 (46%), Gaps = 35/410 (8%)
Query: 166 GTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN 225
G + + ++ D P P+ P+D+ VS GE A C A G P P I W + E + +
Sbjct: 55 GYTGSRLRQEDFP---PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETD 111
Query: 226 E----NRYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEE 276
+ + + +G+L +VH + D+G++ C+A+N G+A S A + V ++
Sbjct: 112 KDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD 171
Query: 277 HKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNG 336
F P + E +VM G P+P ++W +G + + I G
Sbjct: 172 --------FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGG 223
Query: 337 SILIKNVQNSDAGVYTCQVENIHGKISASV-PLEVTAPPSFIVVPTNQTAIIGDNVWFTC 395
++I + SDAG Y C N+ G+ + V L V PSF+ P+N + D+ F C
Sbjct: 224 KLMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKC 283
Query: 396 KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
+A+G P P+++W ++ LP + DD+ L + +VT D Y C AEN G EA
Sbjct: 284 EARGDPVPTVRWRKDDGELP-KSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEA 341
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV----- 510
SA LT+++ PP V+KP D +V CE P +I WR++GS+ +
Sbjct: 342 SATLTVQE----PPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQ 397
Query: 511 ---EDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
R S++ G L I NV +D G Y C N G +L V D
Sbjct: 398 PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 447
Score = 149 bits (360), Expect = 9e-35
Identities = 95/307 (30%), Positives = 146/307 (47%), Gaps = 29/307 (9%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P+++ V+ ++A F C A G+P P + W +D +P ++RYEI D+ TL +
Sbjct: 260 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP--KSRYEIRDDHTLKI 317
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C+A+N+ GKA + A + V+ PP FV P+ + + T
Sbjct: 318 RKVTAGDMGSYTCVAENMVGKAEAS-ATLTVQE---------PPHFVVKPRDQVVALGRT 367
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
V F C ATG P+P + W G + LL + R + G + I NVQ SD G Y
Sbjct: 368 -VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 426
Query: 352 TCQVENIHGKISASVPLEVT------APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ N+ G I LEVT PP P NQT + +C A G+P P+I
Sbjct: 427 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTI 486
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ-- 463
W ++ V++ + + +N L + D Y C A G SA + +++
Sbjct: 487 LWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFG 546
Query: 464 VEIIPPR 470
V + PPR
Sbjct: 547 VPVQPPR 553
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 172 bits (418), Expect = 8e-42
Identities = 120/406 (29%), Positives = 194/406 (47%), Gaps = 35/406 (8%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+DV VS GE C A G P P I W +D E + ++ +
Sbjct: 24 LRQEDFP---PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRS 80
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH ++ D+G + C+A+N G+A S+ A + V ++ +
Sbjct: 81 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPT 140
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
V V+ E +++ G P+P + W + R+ E I G ++I N
Sbjct: 141 DVVVAA--------GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISN 192
Query: 343 VQNSDAGVYTCQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG+YTC N+ G + S L V P+F+ P NQ + + V F C+ +G P
Sbjct: 193 TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDP 252
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+P+++W ++ LP G + DD L + + D+ Y C AEN G +EASA LT+
Sbjct: 253 QPTVRWKKDDADLP-RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 310
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
PP+ V++P D + +V PCE + P ++ W+K+GS+ + +
Sbjct: 311 R----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS 366
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
R S++ G L I N+ +D G Y C A G A L V D L
Sbjct: 367 RCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVL 412
Score = 171 bits (416), Expect = 1e-41
Identities = 117/386 (30%), Positives = 177/386 (45%), Gaps = 23/386 (5%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P DV V+ GE A+ C G P P I W +D I E R I G LM+
Sbjct: 135 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNT 193
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G++ C+ N+ G+ S PA++ V + P F+ P + + E +V
Sbjct: 194 RKSDAGMYTCVGTNMVGERDSDPAELTVFER---------PTFLRRPINQVV-LEEEAVE 243
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C G P+P V W + L R ++ + ++ IK ++D G Y C EN GK+
Sbjct: 244 FRCQVQGDPQPTVRWK-KDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKM 302
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPITGN 419
AS L V APP F+V P +Q G V F C+ KG P+P++ W + ++ P
Sbjct: 303 EASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ 362
Query: 420 LVLS----DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPRIVL 473
S +LT+ + R D Y C+A G I A A L + V + PP I+
Sbjct: 363 QPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 422
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTD 532
P + + + + C+ P I W K+G D R +I G+L I+N+ ++D
Sbjct: 423 GPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISD 482
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDN 558
TG Y C A + G + S L V ++
Sbjct: 483 TGTYTCVATSSSGETSWSAVLDVTES 508
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 172 bits (418), Expect = 8e-42
Identities = 120/406 (29%), Positives = 194/406 (47%), Gaps = 35/406 (8%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+DV VS GE C A G P P I W +D E + ++ +
Sbjct: 40 LRQEDFP---PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRS 96
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH ++ D+G + C+A+N G+A S+ A + V ++ +
Sbjct: 97 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPT 156
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
V V+ E +++ G P+P + W + R+ E I G ++I N
Sbjct: 157 DVVVAA--------GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISN 208
Query: 343 VQNSDAGVYTCQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG+YTC N+ G + S L V P+F+ P NQ + + V F C+ +G P
Sbjct: 209 TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDP 268
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+P+++W ++ LP G + DD L + + D+ Y C AEN G +EASA LT+
Sbjct: 269 QPTVRWKKDDADLP-RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 326
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
PP+ V++P D + +V PCE + P ++ W+K+GS+ + +
Sbjct: 327 R----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS 382
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
R S++ G L I N+ +D G Y C A G A L V D L
Sbjct: 383 RCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVL 428
Score = 171 bits (416), Expect = 1e-41
Identities = 117/386 (30%), Positives = 177/386 (45%), Gaps = 23/386 (5%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P DV V+ GE A+ C G P P I W +D I E R I G LM+
Sbjct: 151 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNT 209
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G++ C+ N+ G+ S PA++ V + P F+ P + + E +V
Sbjct: 210 RKSDAGMYTCVGTNMVGERDSDPAELTVFER---------PTFLRRPINQVV-LEEEAVE 259
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C G P+P V W + L R ++ + ++ IK ++D G Y C EN GK+
Sbjct: 260 FRCQVQGDPQPTVRWK-KDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKM 318
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPITGN 419
AS L V APP F+V P +Q G V F C+ KG P+P++ W + ++ P
Sbjct: 319 EASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ 378
Query: 420 LVLS----DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPRIVL 473
S +LT+ + R D Y C+A G I A A L + V + PP I+
Sbjct: 379 QPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 438
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTD 532
P + + + + C+ P I W K+G D R +I G+L I+N+ ++D
Sbjct: 439 GPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISD 498
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDN 558
TG Y C A + G + S L V ++
Sbjct: 499 TGTYTCVATSSSGETSWSAVLDVTES 524
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 172 bits (418), Expect = 8e-42
Identities = 122/404 (30%), Positives = 187/404 (46%), Gaps = 32/404 (7%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+D+ VS GE A C A G P P I W + E + ++ +
Sbjct: 22 LRQEDFP---PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH + D+G++ C+A+N G+A S A + V ++
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------ 132
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
F P + E +VM G P+P ++W +G + + I G ++I
Sbjct: 133 --FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY 190
Query: 343 VQNSDAGVYTCQVENIHGKISASV-PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG Y C N+ G+ + V L V PSF+ P+N + D+ F C+A+G P
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDP 250
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
P+++W ++ LP + DD+ L + +VT D Y C AEN G EASA LT+
Sbjct: 251 VPTVRWRKDDGELP-KSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
QV PP V+KP D +V CE P +I WR++GS+ +
Sbjct: 309 -QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS 367
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
R S++ G L I NV +D G Y C N G +L V D
Sbjct: 368 RFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Score = 167 bits (406), Expect = 2e-40
Identities = 122/392 (31%), Positives = 177/392 (45%), Gaps = 26/392 (6%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P+DV V+ GE AV C G P P I W +D + + R I G LM+
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYT 191
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G + C+ N+ G+ S+ A++ V + P FV P +++ S
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLER---------PSFVKRPSNLAVTVDD-SAE 241
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C A G P P V W + L R ++ + ++ I+ V D G YTC EN+ GK
Sbjct: 242 FKCEARGDPVPTVRWR-KDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 363 SASVPLEV---TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR----NTVIL- 414
AS L V + PP F+V P +Q +G V F C+A G P+P+I W R N +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 360
Query: 415 --PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPR 470
P + + +LT+ V R D Y C+ N G I A L + V + PP
Sbjct: 361 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 420
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVS 529
I P + + + + C P +I WRKDG + +D RI G L IR
Sbjct: 421 IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAK 480
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
+ DTGRY C A G T S ++ V++ +P
Sbjct: 481 LGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Score = 151 bits (367), Expect = 1e-35
Identities = 96/307 (31%), Positives = 148/307 (48%), Gaps = 26/307 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P+++ V+ ++A F C A G+P P + W +D +P ++RYEI D+ TL +
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP--KSRYEIRDDHTLKI 278
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C+A+N+ GKA + A + V+ +E PP FV P+ + + T
Sbjct: 279 RKVTAGDMGSYTCVAENMVGKAEAS-ATLTVQVGSE------PPHFVVKPRDQVVALGRT 331
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
V F C ATG P+P + W G + LL + R + G + I NVQ SD G Y
Sbjct: 332 -VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 390
Query: 352 TCQVENIHGKISASVPLEVT------APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ N+ G I LEVT PP P NQT + +C A G+P P+I
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTI 450
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ-- 463
W ++ V++ + + +N L + D Y C A G SA + +++
Sbjct: 451 LWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFG 510
Query: 464 VEIIPPR 470
V + PPR
Sbjct: 511 VPVQPPR 517
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/222 (27%), Positives = 92/222 (41%), Gaps = 13/222 (5%)
Query: 157 TCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL 216
TC V +A + + P F +P D V+ G F C ATG P P I W
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 349
Query: 217 RD-------SEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMI 269
R+ S P + +R+ + G L + +D G + C NVAG +K +
Sbjct: 350 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409
Query: 270 VRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
A+ PPV P + ++ T V+ C ATG P P + W +G + +
Sbjct: 410 TDVIADR----PPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPTILWRKDGVLVSTQDS 464
Query: 330 IILQ-HNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
I Q NG + I+ + D G YTC G+ + S +EV
Sbjct: 465 RIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 506
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 172 bits (418), Expect = 8e-42
Identities = 122/404 (30%), Positives = 187/404 (46%), Gaps = 32/404 (7%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+D+ VS GE A C A G P P I W + E + ++ +
Sbjct: 22 LRQEDFP---PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH + D+G++ C+A+N G+A S A + V ++
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------ 132
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
F P + E +VM G P+P ++W +G + + I G ++I
Sbjct: 133 --FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY 190
Query: 343 VQNSDAGVYTCQVENIHGKISASV-PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG Y C N+ G+ + V L V PSF+ P+N + D+ F C+A+G P
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDP 250
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
P+++W ++ LP + DD+ L + +VT D Y C AEN G EASA LT+
Sbjct: 251 VPTVRWRKDDGELP-KSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
QV PP V+KP D +V CE P +I WR++GS+ +
Sbjct: 309 -QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS 367
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
R S++ G L I NV +D G Y C N G +L V D
Sbjct: 368 RFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Score = 167 bits (406), Expect = 2e-40
Identities = 122/392 (31%), Positives = 177/392 (45%), Gaps = 26/392 (6%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P+DV V+ GE AV C G P P I W +D + + R I G LM+
Sbjct: 133 FRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYT 191
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G + C+ N+ G+ S+ A++ V + P FV P +++ S
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLER---------PSFVKRPSNLAVTVDD-SAE 241
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C A G P P V W + L R ++ + ++ I+ V D G YTC EN+ GK
Sbjct: 242 FKCEARGDPVPTVRWR-KDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 363 SASVPLEV---TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR----NTVIL- 414
AS L V + PP F+V P +Q +G V F C+A G P+P+I W R N +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 360
Query: 415 --PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPR 470
P + + +LT+ V R D Y C+ N G I A L + V + PP
Sbjct: 361 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 420
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVS 529
I P + + + + C P +I WRKDG + +D RI G L IR
Sbjct: 421 IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAK 480
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
+ DTGRY C A G T S ++ V++ +P
Sbjct: 481 LGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Score = 151 bits (367), Expect = 1e-35
Identities = 96/307 (31%), Positives = 148/307 (48%), Gaps = 26/307 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P+++ V+ ++A F C A G+P P + W +D +P ++RYEI D+ TL +
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP--KSRYEIRDDHTLKI 278
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C+A+N+ GKA + A + V+ +E PP FV P+ + + T
Sbjct: 279 RKVTAGDMGSYTCVAENMVGKAEAS-ATLTVQVGSE------PPHFVVKPRDQVVALGRT 331
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
V F C ATG P+P + W G + LL + R + G + I NVQ SD G Y
Sbjct: 332 -VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 390
Query: 352 TCQVENIHGKISASVPLEVT------APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ N+ G I LEVT PP P NQT + +C A G+P P+I
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTI 450
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ-- 463
W ++ V++ + + +N L + D Y C A G SA + +++
Sbjct: 451 LWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFG 510
Query: 464 VEIIPPR 470
V + PPR
Sbjct: 511 VPVQPPR 517
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/222 (27%), Positives = 92/222 (41%), Gaps = 13/222 (5%)
Query: 157 TCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL 216
TC V +A + + P F +P D V+ G F C ATG P P I W
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 349
Query: 217 RD-------SEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMI 269
R+ S P + +R+ + G L + +D G + C NVAG +K +
Sbjct: 350 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409
Query: 270 VRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
A+ PPV P + ++ T V+ C ATG P P + W +G + +
Sbjct: 410 TDVIADR----PPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPTILWRKDGVLVSTQDS 464
Query: 330 IILQ-HNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
I Q NG + I+ + D G YTC G+ + S +EV
Sbjct: 465 RIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 506
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 172 bits (418), Expect = 8e-42
Identities = 120/406 (29%), Positives = 194/406 (47%), Gaps = 35/406 (8%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+DV VS GE C A G P P I W +D E + ++ +
Sbjct: 26 LRQEDFP---PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRS 82
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH ++ D+G + C+A+N G+A S+ A + V ++ +
Sbjct: 83 HRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPT 142
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
V V+ E +++ G P+P + W + R+ E I G ++I N
Sbjct: 143 DVVVAA--------GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISN 194
Query: 343 VQNSDAGVYTCQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG+YTC N+ G + S L V P+F+ P NQ + + V F C+ +G P
Sbjct: 195 TRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDP 254
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+P+++W ++ LP G + DD L + + D+ Y C AEN G +EASA LT+
Sbjct: 255 QPTVRWKKDDADLP-RGRYDIKDD-YTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTV 312
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
PP+ V++P D + +V PCE + P ++ W+K+GS+ + +
Sbjct: 313 R----APPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNS 368
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
R S++ G L I N+ +D G Y C A G A L V D L
Sbjct: 369 RCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVL 414
Score = 171 bits (416), Expect = 1e-41
Identities = 117/386 (30%), Positives = 177/386 (45%), Gaps = 23/386 (5%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P DV V+ GE A+ C G P P I W +D I E R I G LM+
Sbjct: 137 FRQNPTDVVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNT 195
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G++ C+ N+ G+ S PA++ V + P F+ P + + E +V
Sbjct: 196 RKSDAGMYTCVGTNMVGERDSDPAELTVFER---------PTFLRRPINQVV-LEEEAVE 245
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C G P+P V W + L R ++ + ++ IK ++D G Y C EN GK+
Sbjct: 246 FRCQVQGDPQPTVRWK-KDDADLPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKM 304
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPITGN 419
AS L V APP F+V P +Q G V F C+ KG P+P++ W + ++ P
Sbjct: 305 EASATLTVRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQ 364
Query: 420 LVLS----DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPRIVL 473
S +LT+ + R D Y C+A G I A A L + V + PP I+
Sbjct: 365 QPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQ 424
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTD 532
P + + + + C+ P I W K+G D R +I G+L I+N+ ++D
Sbjct: 425 GPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISD 484
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDN 558
TG Y C A + G + S L V ++
Sbjct: 485 TGTYTCVATSSSGETSWSAVLDVTES 510
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 171 bits (417), Expect = 1e-41
Identities = 122/404 (30%), Positives = 187/404 (46%), Gaps = 32/404 (7%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----N 227
++ D P P+ P+D+ VS GE A C A G P P I W + E + ++ +
Sbjct: 22 LRQEDFP---PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRS 78
Query: 228 RYEIFDNGTL----MVH-EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+ +G+L +VH + D+G++ C+A+N G+A S A + V ++
Sbjct: 79 HRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD------ 132
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN 342
F P + E +VM G P+P ++W +G + + I G ++I
Sbjct: 133 --FRQNPSDVMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITY 190
Query: 343 VQNSDAGVYTCQVENIHGKISASV-PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+ SDAG Y C N+ G+ + V L V PSF+ P+N + D+ F C+A+G P
Sbjct: 191 TRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDP 250
Query: 402 KPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
P+++W ++ LP + DD+ L + +VT D Y C AEN G EASA LT+
Sbjct: 251 VPTVRWRKDDGELP-KSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308
Query: 462 EQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--------EDD 513
QV PP V+KP D +V CE P +I WR++GS+ +
Sbjct: 309 -QVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSS 367
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
R S++ G L I NV +D G Y C N G +L V D
Sbjct: 368 RFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 411
Score = 166 bits (403), Expect = 5e-40
Identities = 122/392 (31%), Positives = 176/392 (44%), Gaps = 26/392 (6%)
Query: 184 FESEPNDVEVSFGENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA 242
F P+DV V GE AV C G P P I W +D + + R I G LM+
Sbjct: 133 FRQNPSDVMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYT 191
Query: 243 NENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
++D G + C+ N+ G+ S+ A++ V + P FV P +++ S
Sbjct: 192 RKSDAGKYVCVGTNMVGERESEVAELTVLER---------PSFVKRPSNLAVTVDD-SAE 241
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F C A G P P V W + L R ++ + ++ I+ V D G YTC EN+ GK
Sbjct: 242 FKCEARGDPVPTVRWR-KDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKA 300
Query: 363 SASVPLEV---TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR----NTVIL- 414
AS L V + PP F+V P +Q +G V F C+A G P+P+I W R N +
Sbjct: 301 EASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSY 360
Query: 415 --PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV--EIIPPR 470
P + + +LT+ V R D Y C+ N G I A L + V + PP
Sbjct: 361 QPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPV 420
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVS 529
I P + + + + C P +I WRKDG + +D RI G L IR
Sbjct: 421 IRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAK 480
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
+ DTGRY C A G T S ++ V++ +P
Sbjct: 481 LGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Score = 151 bits (367), Expect = 1e-35
Identities = 96/307 (31%), Positives = 148/307 (48%), Gaps = 26/307 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P F P+++ V+ ++A F C A G+P P + W +D +P ++RYEI D+ TL +
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELP--KSRYEIRDDHTLKI 278
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C+A+N+ GKA + A + V+ +E PP FV P+ + + T
Sbjct: 279 RKVTAGDMGSYTCVAENMVGKAEAS-ATLTVQVGSE------PPHFVVKPRDQVVALGRT 331
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLL--------NERIILQHNGSILIKNVQNSDAGVY 351
V F C ATG P+P + W G + LL + R + G + I NVQ SD G Y
Sbjct: 332 -VTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 390
Query: 352 TCQVENIHGKISASVPLEVT------APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
CQ N+ G I LEVT PP P NQT + +C A G+P P+I
Sbjct: 391 ICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTI 450
Query: 406 KWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ-- 463
W ++ V++ + + +N L + D Y C A G SA + +++
Sbjct: 451 LWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFG 510
Query: 464 VEIIPPR 470
V + PPR
Sbjct: 511 VPVQPPR 517
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/222 (27%), Positives = 92/222 (41%), Gaps = 13/222 (5%)
Query: 157 TCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL 216
TC V +A + + P F +P D V+ G F C ATG P P I W
Sbjct: 290 TCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWR 349
Query: 217 RD-------SEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMI 269
R+ S P + +R+ + G L + +D G + C NVAG +K +
Sbjct: 350 REGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEV 409
Query: 270 VRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
A+ PPV P + ++ T V+ C ATG P P + W +G + +
Sbjct: 410 TDVIADR----PPPVIRQGPVNQTVAVDGTFVL-SCVATGSPVPTILWRKDGVLVSTQDS 464
Query: 330 IILQ-HNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
I Q NG + I+ + D G YTC G+ + S +EV
Sbjct: 465 RIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 506
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 166 bits (403), Expect = 5e-40
Identities = 124/468 (26%), Positives = 206/468 (44%), Gaps = 34/468 (7%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHI-- 64
D+ +N + ++ F L L L L DN + + G F I
Sbjct: 317 DLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIE 376
Query: 65 -DSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
S+ F L L +L L N+I I + F L L+ L L+NN + SI +F L
Sbjct: 377 DASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFS-QTHL 435
Query: 124 RKLRLDSNALICDCSILWFIRMLENNEWMH-VAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W ++ L +N + H V +C P + G S+ + D C
Sbjct: 436 KELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDF 495
Query: 181 -QPQFESEPNDVEVSFGENAVFTC--VATGEPAPEILWLRDSEVI--PLNENRYEIFDNG 235
+PQ + P + G N TC V++ + +W +DSE++ EN +
Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 555
Query: 236 ------TLMVHEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
T ++H N N D+G ++C+ N G +S+ AK+ V P F+
Sbjct: 556 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM---------PSFLK 606
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P ++W +G + ER ++ + I NV
Sbjct: 607 TPMDLTIRTGAMARL-ECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANV 665
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D G+Y+C +N G +SA+ L V PSFI ++T G+ C A G+P P
Sbjct: 666 KIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAP 725
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG 451
+ W ++ L +T + NQ L +++ +D Y C N G
Sbjct: 726 RLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 773
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/229 (25%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 332 LQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
L++ + + NV +D G Y C V N G S L V PSF+ P + T G
Sbjct: 559 LEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAM 618
Query: 391 VWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAE 447
C A+G P P I W ++ P + + ++ + V +D IY C A+
Sbjct: 619 ARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQ 678
Query: 448 NDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGS 507
N G + A+A LT+ + P + ED + + + C P ++W KD
Sbjct: 679 NTAGGLSANASLTVLET----PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734
Query: 508 RIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +R L II + + D G+Y C N G + ++L V
Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNV 783
Score = 76.6 bits (180), Expect = 6e-13
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 15/200 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD--SEVIPLNENRYEIF-DNGT 236
+ P F P D+ + G A C A G PAP+I W +D ++ E R + ++
Sbjct: 600 EMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV 659
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ D G++ CMA+N AG + + ++ P F+ + +
Sbjct: 660 FFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLET----------PSFIRPLEDKTVTR 709
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER-IILQHNGSILIKNVQNSDAGVYTCQV 355
ET+V+ C A G P P + W + +L+ ER N ++I + DAG YTC +
Sbjct: 710 GETAVL-QCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIM 768
Query: 356 ENIHGKISASVPLEVTAPPS 375
N G + L V + P+
Sbjct: 769 SNTLGTERGHIYLNVISSPN 788
Score = 70.9 bits (166), Expect = 3e-11
Identities = 132/575 (22%), Positives = 223/575 (38%), Gaps = 58/575 (10%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N+I EI+ F + QL+ L L++N + L +G F + I
Sbjct: 150 DLSSNIISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L HL+ L L N I +E TF L L L + N + + G+F G+ + +
Sbjct: 209 PKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEE 267
Query: 126 LRLDSNALI-CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQF 184
L L+ N L + L+ +RML+ ++V+ + S CQ+
Sbjct: 268 LELEHNNLTRVNKGWLYGLRMLQQ---LYVSQNAIERISPDAWEF---------CQR--- 312
Query: 185 ESEPNDVEVSFGE-NAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
+++++S+ + + G E L L D+ V + + + N L +
Sbjct: 313 ---LSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN--LQTLDLR 367
Query: 244 END-DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
N+ E ++ AG + K+I+ + + KS F+ +N ++M
Sbjct: 368 NNEISWAIEDASEAFAGL--TSLTKLIL--QGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F + H+ LL + + ++ N Q+S V E + G+
Sbjct: 424 -SIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHS-VNVSCAHPEWLAGQS 481
Query: 363 SASVPLEVTAPPSFI--VVPTNQTAII---GDNVWFTCKA-KGTPKP-SIKWYRNTVIL- 414
+V L+ F+ + T+ II G NV TC A + P S W +++ IL
Sbjct: 482 ILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILY 541
Query: 415 -PITGNLV--------LSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQV 464
T N V + L L V D+ Y C N G A LT+ ++
Sbjct: 542 DVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM 601
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR---IVEDDRISITVIG 521
P + P D+ ++ C E P I W+KDG + R+ +
Sbjct: 602 ----PSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPED 657
Query: 522 SL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ I NV + D G Y C A N G +A+ LTV
Sbjct: 658 DVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTV 692
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/129 (29%), Positives = 59/129 (45%)
Query: 3 LFFRDVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIK 62
L F +++ N I+ +E F L LRSL + N + L+ GAF G +
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 63 HIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK 122
++ L+ L+QLY+ N I I P+ + RL L L N+L + +F G+
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSL 336
Query: 123 LRKLRLDSN 131
L +L L N
Sbjct: 337 LERLNLGDN 345
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 166 bits (403), Expect = 5e-40
Identities = 124/468 (26%), Positives = 206/468 (44%), Gaps = 34/468 (7%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHI-- 64
D+ +N + ++ F L L L L DN + + G F I
Sbjct: 317 DLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIE 376
Query: 65 -DSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
S+ F L L +L L N+I I + F L L+ L L+NN + SI +F L
Sbjct: 377 DASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFS-QTHL 435
Query: 124 RKLRLDSNALICDCSILWFIRMLENNEWMH-VAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W ++ L +N + H V +C P + G S+ + D C
Sbjct: 436 KELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDF 495
Query: 181 -QPQFESEPNDVEVSFGENAVFTC--VATGEPAPEILWLRDSEVI--PLNENRYEIFDNG 235
+PQ + P + G N TC V++ + +W +DSE++ EN +
Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 555
Query: 236 ------TLMVHEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
T ++H N N D+G ++C+ N G +S+ AK+ V P F+
Sbjct: 556 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM---------PSFLK 606
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P ++W +G + ER ++ + I NV
Sbjct: 607 TPMDLTIRTGAMARL-ECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANV 665
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D G+Y+C +N G +SA+ L V PSFI ++T G+ C A G+P P
Sbjct: 666 KIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAP 725
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG 451
+ W ++ L +T + NQ L +++ +D Y C N G
Sbjct: 726 RLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 773
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/229 (25%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 332 LQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
L++ + + NV +D G Y C V N G S L V PSF+ P + T G
Sbjct: 559 LEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAM 618
Query: 391 VWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAE 447
C A+G P P I W ++ P + + ++ + V +D IY C A+
Sbjct: 619 ARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQ 678
Query: 448 NDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGS 507
N G + A+A LT+ + P + ED + + + C P ++W KD
Sbjct: 679 NTAGGLSANASLTVLET----PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734
Query: 508 RIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +R L II + + D G+Y C N G + ++L V
Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNV 783
Score = 76.6 bits (180), Expect = 6e-13
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 15/200 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD--SEVIPLNENRYEIF-DNGT 236
+ P F P D+ + G A C A G PAP+I W +D ++ E R + ++
Sbjct: 600 EMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV 659
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ D G++ CMA+N AG + + ++ P F+ + +
Sbjct: 660 FFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLET----------PSFIRPLEDKTVTR 709
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER-IILQHNGSILIKNVQNSDAGVYTCQV 355
ET+V+ C A G P P + W + +L+ ER N ++I + DAG YTC +
Sbjct: 710 GETAVL-QCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIM 768
Query: 356 ENIHGKISASVPLEVTAPPS 375
N G + L V + P+
Sbjct: 769 SNTLGTERGHIYLNVISSPN 788
Score = 70.9 bits (166), Expect = 3e-11
Identities = 132/575 (22%), Positives = 223/575 (38%), Gaps = 58/575 (10%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N+I EI+ F + QL+ L L++N + L +G F + I
Sbjct: 150 DLSSNIISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L HL+ L L N I +E TF L L L + N + + G+F G+ + +
Sbjct: 209 PKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEE 267
Query: 126 LRLDSNALI-CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQF 184
L L+ N L + L+ +RML+ ++V+ + S CQ+
Sbjct: 268 LELEHNNLTRVNKGWLYGLRMLQQ---LYVSQNAIERISPDAWEF---------CQR--- 312
Query: 185 ESEPNDVEVSFGE-NAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
+++++S+ + + G E L L D+ V + + + N L +
Sbjct: 313 ---LSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN--LQTLDLR 367
Query: 244 END-DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
N+ E ++ AG + K+I+ + + KS F+ +N ++M
Sbjct: 368 NNEISWAIEDASEAFAGL--TSLTKLIL--QGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F + H+ LL + + ++ N Q+S V E + G+
Sbjct: 424 -SIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHS-VNVSCAHPEWLAGQS 481
Query: 363 SASVPLEVTAPPSFI--VVPTNQTAII---GDNVWFTCKA-KGTPKP-SIKWYRNTVIL- 414
+V L+ F+ + T+ II G NV TC A + P S W +++ IL
Sbjct: 482 ILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILY 541
Query: 415 -PITGNLV--------LSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQV 464
T N V + L L V D+ Y C N G A LT+ ++
Sbjct: 542 DVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM 601
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR---IVEDDRISITVIG 521
P + P D+ ++ C E P I W+KDG + R+ +
Sbjct: 602 ----PSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPED 657
Query: 522 SL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ I NV + D G Y C A N G +A+ LTV
Sbjct: 658 DVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTV 692
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/129 (29%), Positives = 59/129 (45%)
Query: 3 LFFRDVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIK 62
L F +++ N I+ +E F L LRSL + N + L+ GAF G +
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 63 HIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK 122
++ L+ L+QLY+ N I I P+ + RL L L N+L + +F G+
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSL 336
Query: 123 LRKLRLDSN 131
L +L L N
Sbjct: 337 LERLNLGDN 345
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 166 bits (403), Expect = 5e-40
Identities = 124/468 (26%), Positives = 206/468 (44%), Gaps = 34/468 (7%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHI-- 64
D+ +N + ++ F L L L L DN + + G F I
Sbjct: 317 DLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIE 376
Query: 65 -DSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
S+ F L L +L L N+I I + F L L+ L L+NN + SI +F L
Sbjct: 377 DASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFS-QTHL 435
Query: 124 RKLRLDSNALICDCSILWFIRMLENNEWMH-VAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W ++ L +N + H V +C P + G S+ + D C
Sbjct: 436 KELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDF 495
Query: 181 -QPQFESEPNDVEVSFGENAVFTC--VATGEPAPEILWLRDSEVI--PLNENRYEIFDNG 235
+PQ + P + G N TC V++ + +W +DSE++ EN +
Sbjct: 496 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 555
Query: 236 ------TLMVHEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
T ++H N N D+G ++C+ N G +S+ AK+ V P F+
Sbjct: 556 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM---------PSFLK 606
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P ++W +G + ER ++ + I NV
Sbjct: 607 TPMDLTIRTGAMARL-ECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANV 665
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D G+Y+C +N G +SA+ L V PSFI ++T G+ C A G+P P
Sbjct: 666 KIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAP 725
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG 451
+ W ++ L +T + NQ L +++ +D Y C N G
Sbjct: 726 RLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 773
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/229 (25%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 332 LQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
L++ + + NV +D G Y C V N G S L V PSF+ P + T G
Sbjct: 559 LEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAM 618
Query: 391 VWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAE 447
C A+G P P I W ++ P + + ++ + V +D IY C A+
Sbjct: 619 ARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQ 678
Query: 448 NDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGS 507
N G + A+A LT+ + P + ED + + + C P ++W KD
Sbjct: 679 NTAGGLSANASLTVLET----PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 734
Query: 508 RIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +R L II + + D G+Y C N G + ++L V
Sbjct: 735 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNV 783
Score = 76.6 bits (180), Expect = 6e-13
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 15/200 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD--SEVIPLNENRYEIF-DNGT 236
+ P F P D+ + G A C A G PAP+I W +D ++ E R + ++
Sbjct: 600 EMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV 659
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ D G++ CMA+N AG + + ++ P F+ + +
Sbjct: 660 FFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLET----------PSFIRPLEDKTVTR 709
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER-IILQHNGSILIKNVQNSDAGVYTCQV 355
ET+V+ C A G P P + W + +L+ ER N ++I + DAG YTC +
Sbjct: 710 GETAVL-QCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIM 768
Query: 356 ENIHGKISASVPLEVTAPPS 375
N G + L V + P+
Sbjct: 769 SNTLGTERGHIYLNVISSPN 788
Score = 70.9 bits (166), Expect = 3e-11
Identities = 132/575 (22%), Positives = 223/575 (38%), Gaps = 58/575 (10%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N+I EI+ F + QL+ L L++N + L +G F + I
Sbjct: 150 DLSSNIISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L HL+ L L N I +E TF L L L + N + + G+F G+ + +
Sbjct: 209 PKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEE 267
Query: 126 LRLDSNALI-CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQF 184
L L+ N L + L+ +RML+ ++V+ + S CQ+
Sbjct: 268 LELEHNNLTRVNKGWLYGLRMLQQ---LYVSQNAIERISPDAWEF---------CQR--- 312
Query: 185 ESEPNDVEVSFGE-NAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
+++++S+ + + G E L L D+ V + + + N L +
Sbjct: 313 ---LSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN--LQTLDLR 367
Query: 244 END-DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
N+ E ++ AG + K+I+ + + KS F+ +N ++M
Sbjct: 368 NNEISWAIEDASEAFAGL--TSLTKLIL--QGNQIKSITKKAFIGLESLEHLDLNNNAIM 423
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F + H+ LL + + ++ N Q+S V E + G+
Sbjct: 424 -SIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHS-VNVSCAHPEWLAGQS 481
Query: 363 SASVPLEVTAPPSFI--VVPTNQTAII---GDNVWFTCKA-KGTPKP-SIKWYRNTVIL- 414
+V L+ F+ + T+ II G NV TC A + P S W +++ IL
Sbjct: 482 ILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILY 541
Query: 415 -PITGNLV--------LSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQV 464
T N V + L L V D+ Y C N G A LT+ ++
Sbjct: 542 DVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM 601
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR---IVEDDRISITVIG 521
P + P D+ ++ C E P I W+KDG + R+ +
Sbjct: 602 ----PSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPED 657
Query: 522 SL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ I NV + D G Y C A N G +A+ LTV
Sbjct: 658 DVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTV 692
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/129 (29%), Positives = 59/129 (45%)
Query: 3 LFFRDVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIK 62
L F +++ N I+ +E F L LRSL + N + L+ GAF G +
Sbjct: 217 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 276
Query: 63 HIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK 122
++ L+ L+QLY+ N I I P+ + RL L L N+L + +F G+
Sbjct: 277 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSL 336
Query: 123 LRKLRLDSN 131
L +L L N
Sbjct: 337 LERLNLGDN 345
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 166 bits (403), Expect = 5e-40
Identities = 124/468 (26%), Positives = 206/468 (44%), Gaps = 34/468 (7%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHI-- 64
D+ +N + ++ F L L L L DN + + G F I
Sbjct: 325 DLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIE 384
Query: 65 -DSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
S+ F L L +L L N+I I + F L L+ L L+NN + SI +F L
Sbjct: 385 DASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFS-QTHL 443
Query: 124 RKLRLDSNALICDCSILWFIRMLENNEWMH-VAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W ++ L +N + H V +C P + G S+ + D C
Sbjct: 444 KELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLAGQSILNVDLKDFVCDDF 503
Query: 181 -QPQFESEPNDVEVSFGENAVFTC--VATGEPAPEILWLRDSEVI--PLNENRYEIFDNG 235
+PQ + P + G N TC V++ + +W +DSE++ EN +
Sbjct: 504 LKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILYDVDTENFVRYWQQA 563
Query: 236 ------TLMVHEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
T ++H N N D+G ++C+ N G +S+ AK+ V P F+
Sbjct: 564 GEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM---------PSFLK 614
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P ++W +G + ER ++ + I NV
Sbjct: 615 TPMDLTIRTGAMARL-ECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANV 673
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D G+Y+C +N G +SA+ L V PSFI ++T G+ C A G+P P
Sbjct: 674 KIEDMGIYSCMAQNTAGGLSANASLTVLETPSFIRPLEDKTVTRGETAVLQCIAGGSPAP 733
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG 451
+ W ++ L +T + NQ L +++ +D Y C N G
Sbjct: 734 RLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLG 781
Score = 83.4 bits (197), Expect = 5e-15
Identities = 59/229 (25%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 332 LQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
L++ + + NV +D G Y C V N G S L V PSF+ P + T G
Sbjct: 567 LEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEMPSFLKTPMDLTIRTGAM 626
Query: 391 VWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAE 447
C A+G P P I W ++ P + + ++ + V +D IY C A+
Sbjct: 627 ARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMGIYSCMAQ 686
Query: 448 NDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGS 507
N G + A+A LT+ + P + ED + + + C P ++W KD
Sbjct: 687 NTAGGLSANASLTVLET----PSFIRPLEDKTVTRGETAVLQCIAGGSPAPRLNWTKDDG 742
Query: 508 RIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +R L II + + D G+Y C N G + ++L V
Sbjct: 743 PLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIMSNTLGTERGHIYLNV 791
Score = 76.6 bits (180), Expect = 6e-13
Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 15/200 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD--SEVIPLNENRYEIF-DNGT 236
+ P F P D+ + G A C A G PAP+I W +D ++ E R + ++
Sbjct: 608 EMPSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV 667
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ D G++ CMA+N AG + + ++ P F+ + +
Sbjct: 668 FFIANVKIEDMGIYSCMAQNTAGGLSANASLTVLET----------PSFIRPLEDKTVTR 717
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER-IILQHNGSILIKNVQNSDAGVYTCQV 355
ET+V+ C A G P P + W + +L+ ER N ++I + DAG YTC +
Sbjct: 718 GETAVL-QCIAGGSPAPRLNWTKDDGPLLVTERHFFAAANQLLIIVDAGLEDAGKYTCIM 776
Query: 356 ENIHGKISASVPLEVTAPPS 375
N G + L V + P+
Sbjct: 777 SNTLGTERGHIYLNVISSPN 796
Score = 70.9 bits (166), Expect = 3e-11
Identities = 132/575 (22%), Positives = 223/575 (38%), Gaps = 58/575 (10%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N+I EI+ F + QL+ L L++N + L +G F + I
Sbjct: 158 DLSSNIISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRMSMIP 216
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L HL+ L L N I +E TF L L L + N + + G+F G+ + +
Sbjct: 217 PKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEE 275
Query: 126 LRLDSNALI-CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQF 184
L L+ N L + L+ +RML+ ++V+ + S CQ+
Sbjct: 276 LELEHNNLTRVNKGWLYGLRMLQQ---LYVSQNAIERISPDAWEF---------CQR--- 320
Query: 185 ESEPNDVEVSFGE-NAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
+++++S+ + + G E L L D+ V + + + N L +
Sbjct: 321 ---LSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN--LQTLDLR 375
Query: 244 END-DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM 302
N+ E ++ AG + K+I+ + + KS F+ +N ++M
Sbjct: 376 NNEISWAIEDASEAFAGL--TSLTKLIL--QGNQIKSITKKAFIGLESLEHLDLNNNAIM 431
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
F + H+ LL + + ++ N Q+S V E + G+
Sbjct: 432 -SIQENAFSQTHLKELILNTSSLLCDCHLKWLLQWLVDNNFQHS-VNVSCAHPEWLAGQS 489
Query: 363 SASVPLEVTAPPSFI--VVPTNQTAII---GDNVWFTCKA-KGTPKP-SIKWYRNTVIL- 414
+V L+ F+ + T+ II G NV TC A + P S W +++ IL
Sbjct: 490 ILNVDLKDFVCDDFLKPQIRTHPETIIALRGMNVTLTCTAVSSSDSPMSTVWRKDSEILY 549
Query: 415 -PITGNLV--------LSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQV 464
T N V + L L V D+ Y C N G A LT+ ++
Sbjct: 550 DVDTENFVRYWQQAGEALEYTSILHLFNVNFTDEGKYQCIVTNHFGSNYSQKAKLTVNEM 609
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR---IVEDDRISITVIG 521
P + P D+ ++ C E P I W+KDG + R+ +
Sbjct: 610 ----PSFLKTPMDLTIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPED 665
Query: 522 SL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ I NV + D G Y C A N G +A+ LTV
Sbjct: 666 DVFFIANVKIEDMGIYSCMAQNTAGGLSANASLTV 700
Score = 62.1 bits (144), Expect = 1e-08
Identities = 38/129 (29%), Positives = 59/129 (45%)
Query: 3 LFFRDVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIK 62
L F +++ N I+ +E F L LRSL + N + L+ GAF G +
Sbjct: 225 LQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLT 284
Query: 63 HIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK 122
++ L+ L+QLY+ N I I P+ + RL L L N+L + +F G+
Sbjct: 285 RVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSL 344
Query: 123 LRKLRLDSN 131
L +L L N
Sbjct: 345 LERLNLGDN 353
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 163 bits (397), Expect = 3e-39
Identities = 131/520 (25%), Positives = 220/520 (42%), Gaps = 34/520 (6%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ FN + ++ F L L +L + +N + + AF G I
Sbjct: 317 DLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIE 376
Query: 67 DV---FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
D+ F L L +L L N I I + F+ L L+ L L +N + S+ +F M KL
Sbjct: 377 DMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 436
Query: 124 RKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W + + ENN V A+C P + G S+ A+ C
Sbjct: 437 QQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDF 496
Query: 181 -QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENR 228
+PQ +P G N F C A+ +P W +D+E++ L
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 229 YEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
E+ + T++ + E +G ++C+ N G ++S AK+ V P F
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML---------PSFTK 607
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P +AW +G + ER ++ + I +V
Sbjct: 608 TPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDV 666
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D GVY+C +N G ISA+ L V PSF+ ++T G+ C A G+P P
Sbjct: 667 KIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPP 726
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+ W ++ L +T + NQ L +++ D Y C N G + L++
Sbjct: 727 KLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIP 786
Query: 464 VEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
P++ D D + V + + V S+ W
Sbjct: 787 TPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 826
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 559 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 618
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 619 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 678
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 679 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 733
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 734 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 784
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/123 (24%), Positives = 57/123 (46%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N + ++ G F L + L L+ N+L + G +G I I D ++
Sbjct: 249 NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWE 308
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ +F L L+ L++ NN++ I +F+G+ L+ L L +
Sbjct: 309 FCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 368
Query: 131 NAL 133
N +
Sbjct: 369 NEI 371
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E++ F L QL+ L LN N + ++ G F I I
Sbjct: 151 DLSSNNISELQTA-FPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L L+ L L+ N+I +++ TF L L L + N + + G+F G+ +
Sbjct: 209 PKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEI 267
Query: 126 LRLDSNAL 133
L+LD N L
Sbjct: 268 LQLDHNNL 275
Score = 36.3 bits (80), Expect = 0.74
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N + I+ +HL LR + LN+N L + I I
Sbjct: 80 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI-PNLGPVSANITLLSLAGNRIVEILP 138
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LRK 125
+ ++ + LE L L N I ++ F L +L LYL++N++ S+ G F + L
Sbjct: 139 EHLKEFQSLETLDLSSNNISELQ-TAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 126 LRLDSNAL 133
L+L+ N +
Sbjct: 197 LKLNRNRI 204
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 163 bits (397), Expect = 3e-39
Identities = 131/520 (25%), Positives = 220/520 (42%), Gaps = 34/520 (6%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ FN + ++ F L L +L + +N + + AF G I
Sbjct: 317 DLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIE 376
Query: 67 DV---FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
D+ F L L +L L N I I + F+ L L+ L L +N + S+ +F M KL
Sbjct: 377 DMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 436
Query: 124 RKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W + + ENN V A+C P + G S+ A+ C
Sbjct: 437 QQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDF 496
Query: 181 -QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENR 228
+PQ +P G N F C A+ +P W +D+E++ L
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 229 YEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
E+ + T++ + E +G ++C+ N G ++S AK+ V P F
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML---------PSFTK 607
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P +AW +G + ER ++ + I +V
Sbjct: 608 TPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDV 666
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D GVY+C +N G ISA+ L V PSF+ ++T G+ C A G+P P
Sbjct: 667 KIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPP 726
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+ W ++ L +T + NQ L +++ D Y C N G + L++
Sbjct: 727 KLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIP 786
Query: 464 VEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
P++ D D + V + + V S+ W
Sbjct: 787 TPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 826
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 559 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 618
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 619 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 678
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 679 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 733
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 734 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 784
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/123 (24%), Positives = 57/123 (46%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N + ++ G F L + L L+ N+L + G +G I I D ++
Sbjct: 249 NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWE 308
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ +F L L+ L++ NN++ I +F+G+ L+ L L +
Sbjct: 309 FCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 368
Query: 131 NAL 133
N +
Sbjct: 369 NEI 371
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E++ F L QL+ L LN N + ++ G F I I
Sbjct: 151 DLSSNNISELQTA-FPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L L+ L L+ N+I +++ TF L L L + N + + G+F G+ +
Sbjct: 209 PKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEI 267
Query: 126 LRLDSNAL 133
L+LD N L
Sbjct: 268 LQLDHNNL 275
Score = 36.3 bits (80), Expect = 0.74
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N + I+ +HL LR + LN+N L + I I
Sbjct: 80 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI-PNLGPVSANITLLSLAGNRIVEILP 138
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LRK 125
+ ++ + LE L L N I ++ F L +L LYL++N++ S+ G F + L
Sbjct: 139 EHLKEFQSLETLDLSSNNISELQ-TAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 126 LRLDSNAL 133
L+L+ N +
Sbjct: 197 LKLNRNRI 204
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 163 bits (397), Expect = 3e-39
Identities = 131/520 (25%), Positives = 220/520 (42%), Gaps = 34/520 (6%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ FN + ++ F L L +L + +N + + AF G I
Sbjct: 317 DLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIE 376
Query: 67 DV---FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
D+ F L L +L L N I I + F+ L L+ L L +N + S+ +F M KL
Sbjct: 377 DMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 436
Query: 124 RKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W + + ENN V A+C P + G S+ A+ C
Sbjct: 437 QQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDF 496
Query: 181 -QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENR 228
+PQ +P G N F C A+ +P W +D+E++ L
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 229 YEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
E+ + T++ + E +G ++C+ N G ++S AK+ V P F
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML---------PSFTK 607
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P +AW +G + ER ++ + I +V
Sbjct: 608 TPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDV 666
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D GVY+C +N G ISA+ L V PSF+ ++T G+ C A G+P P
Sbjct: 667 KIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPP 726
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+ W ++ L +T + NQ L +++ D Y C N G + L++
Sbjct: 727 KLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIP 786
Query: 464 VEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
P++ D D + V + + V S+ W
Sbjct: 787 TPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 826
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 559 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 618
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 619 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 678
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 679 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 733
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 734 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 784
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/123 (24%), Positives = 57/123 (46%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N + ++ G F L + L L+ N+L + G +G I I D ++
Sbjct: 249 NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWE 308
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ +F L L+ L++ NN++ I +F+G+ L+ L L +
Sbjct: 309 FCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 368
Query: 131 NAL 133
N +
Sbjct: 369 NEI 371
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E++ F L QL+ L LN N + ++ G F I I
Sbjct: 151 DLSSNNISELQTA-FPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L L+ L L+ N+I +++ TF L L L + N + + G+F G+ +
Sbjct: 209 PKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEI 267
Query: 126 LRLDSNAL 133
L+LD N L
Sbjct: 268 LQLDHNNL 275
Score = 36.3 bits (80), Expect = 0.74
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N + I+ +HL LR + LN+N L + I I
Sbjct: 80 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI-PNLGPVSANITLLSLAGNRIVEILP 138
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LRK 125
+ ++ + LE L L N I ++ F L +L LYL++N++ S+ G F + L
Sbjct: 139 EHLKEFQSLETLDLSSNNISELQ-TAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 126 LRLDSNAL 133
L+L+ N +
Sbjct: 197 LKLNRNRI 204
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 163 bits (397), Expect = 3e-39
Identities = 131/520 (25%), Positives = 220/520 (42%), Gaps = 34/520 (6%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ FN + ++ F L L +L + +N + + AF G I
Sbjct: 257 DLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIE 316
Query: 67 DV---FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
D+ F L L +L L N I I + F+ L L+ L L +N + S+ +F M KL
Sbjct: 317 DMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 376
Query: 124 RKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W + + ENN V A+C P + G S+ A+ C
Sbjct: 377 QQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDF 436
Query: 181 -QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENR 228
+PQ +P G N F C A+ +P W +D+E++ L
Sbjct: 437 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 496
Query: 229 YEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
E+ + T++ + E +G ++C+ N G ++S AK+ V P F
Sbjct: 497 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML---------PSFTK 547
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P +AW +G + ER ++ + I +V
Sbjct: 548 TPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDV 606
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D GVY+C +N G ISA+ L V PSF+ ++T G+ C A G+P P
Sbjct: 607 KIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPP 666
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+ W ++ L +T + NQ L +++ D Y C N G + L++
Sbjct: 667 KLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIP 726
Query: 464 VEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
P++ D D + V + + V S+ W
Sbjct: 727 TPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 766
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 499 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 558
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 559 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 618
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 619 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 673
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 674 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 724
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/123 (24%), Positives = 57/123 (46%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N + ++ G F L + L L+ N+L + G +G I I D ++
Sbjct: 189 NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWE 248
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ +F L L+ L++ NN++ I +F+G+ L+ L L +
Sbjct: 249 FCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 308
Query: 131 NAL 133
N +
Sbjct: 309 NEI 311
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E++ F L QL+ L LN N + ++ G F I I
Sbjct: 91 DLSSNNISELQTA-FPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 148
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L L+ L L+ N+I +++ TF L L L + N + + G+F G+ +
Sbjct: 149 PKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEI 207
Query: 126 LRLDSNAL 133
L+LD N L
Sbjct: 208 LQLDHNNL 215
Score = 36.3 bits (80), Expect = 0.74
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N + I+ +HL LR + LN+N L + I I
Sbjct: 20 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI-PNLGPVSANITLLSLAGNRIVEILP 78
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LRK 125
+ ++ + LE L L N I ++ F L +L LYL++N++ S+ G F + L
Sbjct: 79 EHLKEFQSLETLDLSSNNISELQ-TAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLV 136
Query: 126 LRLDSNAL 133
L+L+ N +
Sbjct: 137 LKLNRNRI 144
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 163 bits (397), Expect = 3e-39
Identities = 131/520 (25%), Positives = 220/520 (42%), Gaps = 34/520 (6%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ FN + ++ F L L +L + +N + + AF G I
Sbjct: 317 DLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIE 376
Query: 67 DV---FQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKL 123
D+ F L L +L L N I I + F+ L L+ L L +N + S+ +F M KL
Sbjct: 377 DMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 436
Query: 124 RKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQ-- 180
++L L++++L+CDC + W + + ENN V A+C P + G S+ A+ C
Sbjct: 437 QQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDF 496
Query: 181 -QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP---------LNENR 228
+PQ +P G N F C A+ +P W +D+E++ L
Sbjct: 497 PKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQG 556
Query: 229 YEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
E+ + T++ + E +G ++C+ N G ++S AK+ V P F
Sbjct: 557 GEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML---------PSFTK 607
Query: 288 TPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI--ILQHNGSILIKNV 343
TP + + + +C A G P P +AW +G + ER ++ + I +V
Sbjct: 608 TPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDV 666
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
+ D GVY+C +N G ISA+ L V PSF+ ++T G+ C A G+P P
Sbjct: 667 KIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPP 726
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
+ W ++ L +T + NQ L +++ D Y C N G + L++
Sbjct: 727 KLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIP 786
Query: 464 VEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
P++ D D + V + + V S+ W
Sbjct: 787 TPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 826
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 559 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 618
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 619 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 678
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 679 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 733
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 734 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 784
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/123 (24%), Positives = 57/123 (46%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N + ++ G F L + L L+ N+L + G +G I I D ++
Sbjct: 249 NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWE 308
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDS 130
+ L +L L N + ++ +F L L+ L++ NN++ I +F+G+ L+ L L +
Sbjct: 309 FCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKN 368
Query: 131 NAL 133
N +
Sbjct: 369 NEI 371
Score = 45.2 bits (102), Expect = 0.002
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXX-IKHID 65
D+ N I E++ F L QL+ L LN N + ++ G F I I
Sbjct: 151 DLSSNNISELQTA-FPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIP 208
Query: 66 SDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRK 125
+F+ L L+ L L+ N+I +++ TF L L L + N + + G+F G+ +
Sbjct: 209 PKMFK-LPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEI 267
Query: 126 LRLDSNAL 133
L+LD N L
Sbjct: 268 LQLDHNNL 275
Score = 36.3 bits (80), Expect = 0.74
Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%)
Query: 7 DVRFNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDS 66
D+ N + I+ +HL LR + LN+N L + I I
Sbjct: 80 DLSHNRLSFIKASSMSHLQSLREVKLNNNELETI-PNLGPVSANITLLSLAGNRIVEILP 138
Query: 67 DVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPK-LRK 125
+ ++ + LE L L N I ++ F L +L LYL++N++ S+ G F + L
Sbjct: 139 EHLKEFQSLETLDLSSNNISELQ-TAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLLV 196
Query: 126 LRLDSNAL 133
L+L+ N +
Sbjct: 197 LKLNRNRI 204
>AF027971-1|AAG38481.1| 193|Homo sapiens airway lactoperoxidase
protein.
Length = 193
Score = 163 bits (396), Expect = 4e-39
Identities = 80/193 (41%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Query: 966 MQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINPVLHRYD 1025
MQ IT+ +LPI+LG + Y+ Y ++P ISNVF T A RFGH + + R D
Sbjct: 2 MQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLD 60
Query: 1026 ENFETI-PQGHLLLRNAFFSPWRLVDEGGVDPLLRGMFTTPAKLKTSKQNLNSELTEKLF 1084
EN++ P+ L L FF+ WR+V +GG+DPL+RG+ +KL + + EL KLF
Sbjct: 61 ENYQPWGPEPELPLHTXFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLF 120
Query: 1085 YSAHAV-ALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLSGEISDKEVRDKLQE 1143
H + DLAAIN QR RDH P Y WR FC++S+ ++L+ + K + KL
Sbjct: 121 QPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKXKMLAKKLLG 180
Query: 1144 LYGSVHNIDVWVG 1156
LYG+ NID+W+G
Sbjct: 181 LYGTPDNIDIWIG 193
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 161 bits (392), Expect = 1e-38
Identities = 113/399 (28%), Positives = 178/399 (44%), Gaps = 25/399 (6%)
Query: 163 SVTGTSLAAMKHHDLPCQ-QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEV 221
S ++ A KH L Q P + P+ V E + C A+G P P I W ++
Sbjct: 825 SARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLN 884
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
+ + ++ G L + A+ D G + C+AKN AG A K +++V+
Sbjct: 885 VATGVST-QVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQ---------V 933
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILI 340
PPV + + + C A G P+P++ W +G+ + E + +Q +G +L+
Sbjct: 934 PPV-IENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLV 992
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
KN++ DAG YTC EN G+ V L + P F +P +++ +GD +W C A+G+
Sbjct: 993 KNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGS 1052
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P I W N P+T + D L V+R+D Y C AEN G +A + +
Sbjct: 1053 PTPRIGWTVND--RPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVH 1110
Query: 461 LEQVEIIPPRIVLKPEDMDAFKET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISI 517
+++ VL+ E E S+Q+ C + P I W KDG +
Sbjct: 1111 VKEAP------VLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQ 1164
Query: 518 TVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D GRY+C A N+ G V L ++
Sbjct: 1165 LQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ 1203
Score = 156 bits (379), Expect = 4e-37
Identities = 109/384 (28%), Positives = 168/384 (43%), Gaps = 34/384 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P E+ D+ + G +A C A G P P I W +D + + E ++ I +G L+V
Sbjct: 935 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 994
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D G + C A+N G+A + I+ PVF + P R ++ + +
Sbjct: 995 LEGQDAGTYTCTAENAVGRARRRVHLTIL----------VLPVFTTLPGDRSLRLGDR-L 1043
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKN-VQNSDAGVYTCQVENIHG 360
C A G P P + W N + E + Q GS L + V D+G Y C EN G
Sbjct: 1044 WLRCAARGSPTPRIGWTVNDRPV--TEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 1101
Query: 361 KISASVPLEVTAPP-------SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
+ A + V P S++V P +G ++ C +G P P I W ++
Sbjct: 1102 RTQAVSFVHVKEAPVLQGEAFSYLVEP------VGGSIQLDCVVRGDPVPDIHWIKDG-- 1153
Query: 414 LPITGNLVLSD-DNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
LP+ G+ + N +LT+ RDD Y C AEN+ G+ + +L L+ P
Sbjct: 1154 LPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA----PVFQ 1209
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTD 532
++P+DM V + C+ P +I+W + G + R+ GSL + NV D
Sbjct: 1210 VEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGD 1269
Query: 533 TGRYECSAFNDYGRDTASVFLTVK 556
G Y+C A N G TA FL V+
Sbjct: 1270 AGTYDCVAHNLLGSATARAFLVVR 1293
Score = 134 bits (323), Expect = 3e-30
Identities = 95/361 (26%), Positives = 154/361 (42%), Gaps = 20/361 (5%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIP--LNENRYEIFDNGTLMVHEANENDDGLFECMAKN 256
A+ C A+G P P ++W +D + + L + Y + + L++ D FEC+ N
Sbjct: 678 ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 737
Query: 257 VAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVA 316
G+AH + + PP ++ Q F V+ C +TG P P V+
Sbjct: 738 EVGEAH----------RLYQVTVHVPPT-IADDQTDFTVTMMAPVVLTCHSTGIPAPTVS 786
Query: 317 WYFNGERM-LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPS 375
W G ++ + +G++ I AG YTC N G V L V A P
Sbjct: 787 WSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPV 846
Query: 376 FIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVT 435
+P+ A+ + V C+A G P+P+I W + + + TG L + +
Sbjct: 847 VKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNV-ATGVSTQVLPGGQLRIAHAS 905
Query: 436 RDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESV 495
+D Y C A+N G SA+ V +PP I D+ + + +PC+
Sbjct: 906 PEDAGNYLCIAKNSAG----SAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGS 961
Query: 496 PPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLT 554
P +I W KDG + + + +I G L+++N+ D G Y C+A N GR V LT
Sbjct: 962 PEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLT 1021
Query: 555 V 555
+
Sbjct: 1022 I 1022
Score = 123 bits (297), Expect = 4e-27
Identities = 99/387 (25%), Positives = 155/387 (40%), Gaps = 21/387 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + D V+ V TC +TG PAP + W + + + Y + +G L + +
Sbjct: 754 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQ 813
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A G + C A+N AG AH + + +A P P V + E V
Sbjct: 814 ALPIHAGRYTCSARNSAGVAHK---HVFLTVQASPVVKPLPSV--------VRAVAEEEV 862
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ C A+G P+P + W G + + G + I + DAG Y C +N G
Sbjct: 863 LLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGS 922
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPITGNL 420
L V PP + + G + + CKA+G+P+P+I W ++ + G
Sbjct: 923 AMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKF 982
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ + L + + D Y C AEN G LT+ ++ P P D
Sbjct: 983 TIQPSGE-LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI----LVLPVFTTLPGDRSL 1037
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIR-NVSVTDTGRYECS 539
+ + C P I W + + E +S GS + R VS D+G Y C
Sbjct: 1038 RLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG--VSEQDGGSTLQRAAVSREDSGTYVCW 1095
Query: 540 AFNDYGRDTASVFLTVKD-NLLPGDAY 565
A N GR A F+ VK+ +L G+A+
Sbjct: 1096 AENRVGRTQAVSFVHVKEAPVLQGEAF 1122
Score = 116 bits (278), Expect = 8e-25
Identities = 90/333 (27%), Positives = 141/333 (42%), Gaps = 20/333 (6%)
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+L + D G + C+A + AG+A + ++ V S P TP
Sbjct: 368 SLQLEAVGAGDSGTYSCVAVSEAGEAR-RHFQLTVMEPPHIEDSGQPTELSLTPGAPMEL 426
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQV 355
+ C A G P+P++ W+ +G+ + E + + ++NVQ DAG+YTC
Sbjct: 427 L--------CDAQGTPQPNITWHKDGQALTRLENNS-RATRVLRVENVQVRDAGLYTCLA 477
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAIIG---DNVWFTCKAKGTPKPSIKWYRNTV 412
E+ G I S + V APP+ IV P ++G + C + P P I W+R+ +
Sbjct: 478 ESPAGAIEKSFRVRVQAPPN-IVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGI 536
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+L + + + L L ++ D Y C A N G + + + V P I
Sbjct: 537 VLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV----PTIR 592
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVSVT 531
P ++ + +PC+ + VP + WRKD + R I GSL I+ V
Sbjct: 593 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQ 652
Query: 532 DTGRYECSAFNDYGRDTASVFLTVKDNLLPGDA 564
D G Y C A N G D L V LLP +A
Sbjct: 653 DAGHYLCLASNSAGSDRQGRDLRVL-ALLPCEA 684
Score = 96.3 bits (229), Expect = 7e-19
Identities = 75/305 (24%), Positives = 125/305 (40%), Gaps = 19/305 (6%)
Query: 164 VTGTSLAAMKHHDLPCQQPQFESEPNDVEVS--FGENAVFTCVATGEPAPEILWLRDSEV 221
V+ + A++ L Q P P VS G V TC +G PAP + WL+D
Sbjct: 18 VSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMP 77
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
+ + + G L + G + C+A+N +A ++ A
Sbjct: 78 VESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVL---------VA 128
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN----GERMLLNERIILQHNGS 337
P + S + + V DC A G P P VAW + G+ M + R L GS
Sbjct: 129 PRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLD-GGS 187
Query: 338 ILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII---GDNVWFT 394
+++K + SDAG YTC N G+ + + V PP+ ++ G+ V
Sbjct: 188 LVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMV 247
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C +G+P + W ++ + LP++ +L L + +V D I+ C A + G+ +
Sbjct: 248 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 307
Query: 455 ASAVL 459
+ L
Sbjct: 308 RNFTL 312
Score = 96.3 bits (229), Expect = 7e-19
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 7/258 (2%)
Query: 302 MFDCTATGFPKPHVAWYFNGERM---LLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C A+G PKP V W+ +G+++ L L + ++L+ D+ + C V N
Sbjct: 679 LLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNE 738
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G+ + V PP+ T+ T + V TC + G P P++ W + L G
Sbjct: 739 VGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARG 798
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + L + + Y C A N G+ LT++ ++ P P +
Sbjct: 799 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKP----LPSVV 854
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
A E V +PCE +P +I W+K+G + + G L I + S D G Y C
Sbjct: 855 RAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLC 914
Query: 539 SAFNDYGRDTASVFLTVK 556
A N G L V+
Sbjct: 915 IAKNSAGSAMGKTRLVVQ 932
Score = 93.9 bits (223), Expect = 3e-18
Identities = 97/386 (25%), Positives = 156/386 (40%), Gaps = 31/386 (8%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
GE C G P + WL+D +PL++ TL + + D G+F C+A
Sbjct: 241 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAA 300
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
+ AG A + FV+ A+ F C + K
Sbjct: 301 SPAGVADRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGA----FPCLSCRGMK--- 353
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPS 375
+GE +L L+ S+ ++ V D+G Y+C + G+ L V PP
Sbjct: 354 ----DGEPLLSQS---LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 406
Query: 376 F--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLE 433
PT + G + C A+GTP+P+I W+++ L N S + L +
Sbjct: 407 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN--NSRATRVLRVEN 464
Query: 434 VTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV--LKPEDMDAFKETSVQMPCE 491
V D +Y C AE+ G IE S + ++ PP IV P + + + C
Sbjct: 465 VQVRDAGLYTCLAESPAGAIEKSFRVRVQ----APPNIVGPRGPRFVVGLAPGQLVLECS 520
Query: 492 IESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTAS 550
+E+ P I W +DG + ED G + ++ +S D+G Y C+A N G + S
Sbjct: 521 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG--STS 578
Query: 551 VFLTVKDNLLP----GDAYVNIALTQ 572
V V+ + +P G VN+++ Q
Sbjct: 579 VAFRVEIHTVPTIRSGPPAVNVSVNQ 604
Score = 90.6 bits (215), Expect = 3e-17
Identities = 84/384 (21%), Positives = 148/384 (38%), Gaps = 45/384 (11%)
Query: 171 AMKHHDLPCQQP---QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN 227
A +H L +P + +P ++ ++ G C A G P P I W +D + + EN
Sbjct: 393 ARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLEN 452
Query: 228 RYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVS 287
L V D GL+ C+A++ AG A K ++ V+ APP V
Sbjct: 453 NSRA--TRVLRVENVQVRDAGLYTCLAESPAG-AIEKSFRVRVQ---------APPNIVG 500
Query: 288 TPQKRFAK-INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQN 345
RF + ++ +C+ P P + W+ +G + + G L ++ +
Sbjct: 501 PRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST 560
Query: 346 SDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
+D+G Y+C N G S + +E+ P+ P + C+A G P P +
Sbjct: 561 ADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLV 620
Query: 406 KWYRNTVIL-PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
W ++ V L P + + + +L + V D Y C A N G L
Sbjct: 621 SWRKDRVPLDPRSPRFEILPEG-SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL----- 674
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI---VEDDRISITVIG 521
R++ +PCE P + W KDG ++ ++ +
Sbjct: 675 -----RVL-------------ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 716
Query: 522 SLIIRNVSVTDTGRYECSAFNDYG 545
+L++ D+ ++EC N+ G
Sbjct: 717 ALLLTAPGPQDSAQFECVVSNEVG 740
Score = 90.2 bits (214), Expect = 4e-17
Identities = 79/320 (24%), Positives = 128/320 (40%), Gaps = 27/320 (8%)
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L + EA +D GL+ C NVAG+A + + V+ PP F + + +++
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEA-VRTFTLTVQ---------VPPTFENPKTETVSQV 50
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTC 353
+ ++ C +G P P V W +RM + ++ G + + +Q + AG YTC
Sbjct: 51 AGSPLVLTCDVSGVPAPTVTWL--KDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTC 108
Query: 354 QVENIHGKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
EN + + V P V + G V C+A G P P + W ++
Sbjct: 109 VAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDG 168
Query: 412 VIL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPP 469
L + +L D +L L + D Y C A N G E + + T+ ++PP
Sbjct: 169 SPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAG--EDARLHTVN--VLVPP 224
Query: 470 RIVLKPEDMDAFKETS---VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLII 525
I + V M C + PP + W KDG + R + G +L I
Sbjct: 225 TIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRI 284
Query: 526 RNVSVTDTGRYECSAFNDYG 545
V + D G + C A + G
Sbjct: 285 SKVQLADAGIFTCVAASPAG 304
Score = 87.8 bits (208), Expect = 2e-16
Identities = 59/216 (27%), Positives = 96/216 (44%), Gaps = 14/216 (6%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTA-IIGDNVWFTCKAK 398
I+ Q SD G+Y+C+V N+ G+ + L V PP+F T + + G + TC
Sbjct: 3 IQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVS 62
Query: 399 GTPKPSIKWYRNTVILPITGNLV--LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS 456
G P P++ W ++ +P+ + V + L L + Y C AEN +A
Sbjct: 63 GVPAPTVTWLKDR--MPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN----TQAE 116
Query: 457 AVLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
A ++ PRI + + V++ CE + PP + W KDGS + +D
Sbjct: 117 ARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMG 176
Query: 515 ISITVI---GSLIIRNVSVTDTGRYECSAFNDYGRD 547
+ GSL+++ + +D G Y C A N G D
Sbjct: 177 PHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPAGED 212
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3864 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3912
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3973 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4032
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4033 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4088
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4089 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4148
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4149 MAANVAGSSSTSTKLTV 4165
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 108/362 (29%), Positives = 167/362 (46%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2218 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2277
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2278 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2329
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2330 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2389
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PSI W+++ + ++ ++ + + L L++ T
Sbjct: 2390 HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2449
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2450 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2505
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2565
Query: 554 TV 555
V
Sbjct: 2566 NV 2567
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3685
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3686 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3734
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3794
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3795 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3854
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3855 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3910
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3911 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3970
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3971 NAAGSAHRHVTLHVHE 3986
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3517 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3626
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3627 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3686
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3746
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3747 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3802
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3803 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3862
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 155 bits (375), Expect = 1e-36
Identities = 99/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 154 bits (373), Expect = 2e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3713 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3772
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3773 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3822
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3823 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3881
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3882 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3941
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3942 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3997
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3998 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4057
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4058 CVAQNPAGTALGKIKLNVQ 4076
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3985 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4040
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4041 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4089
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4090 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4149
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4150 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4209
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4210 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4265
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4266 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4324
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 4325 TYVCTAENSVGFVKAIGFVYVKE 4347
Score = 153 bits (370), Expect = 5e-36
Identities = 111/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4147 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4202
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4203 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4257
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4258 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4311
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P+N +G N
Sbjct: 4312 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4370
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4371 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4430 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4485
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4486 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4516
Score = 151 bits (365), Expect = 2e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 147 bits (357), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3008 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSES-- 3065
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3066 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3119
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3178
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3238 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3293
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3294 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 144 bits (348), Expect = 2e-33
Identities = 98/383 (25%), Positives = 171/383 (44%), Gaps = 23/383 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVILP 415
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTD 2240
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIVL 473
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 SMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSGS 2297
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+D
Sbjct: 2298 HPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSD 2357
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
TGRY C A N G L+V
Sbjct: 2358 TGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 141 bits (341), Expect = 2e-32
Identities = 105/377 (27%), Positives = 160/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P I W +D + L+ N I G ++ + + D
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2451
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2452 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2501
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2502 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2561
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2562 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2622 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2677
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2678 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2737
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2738 SDTGRYTCVASNIAGED 2754
Score = 138 bits (335), Expect = 9e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2937
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2938 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2987
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2988 VSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 3047
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3048 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3107
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3108 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3161
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3162 VETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQ 3242
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4065 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4120
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4121 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4170
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4171 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4228
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4229 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4288
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 4289 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 4346
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4400
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437
Score = 135 bits (326), Expect = 1e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 3364 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 3420
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 3421 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 3473
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 3474 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 3533
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 3534 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 3593
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 3594 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 3649
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 3650 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 1024 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 1083
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 1143
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 1144 DSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3151 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 3210
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3211 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3262
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3263 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3321
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 3322 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 3381
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3382 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3437
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3438 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3497
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3498 TEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 1472
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 1473 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 1533 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 1592
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1593 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 1648
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 1649 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 1708
Query: 535 RYECSA 540
+Y C A
Sbjct: 1709 QYICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2739
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2740 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2798
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2799 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2859 LQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2918
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2919 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2975
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2976 VVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3035
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3036 IAINQAGESKKKFSLTV 3052
Score = 117 bits (281), Expect = 3e-25
Identities = 93/314 (29%), Positives = 140/314 (44%), Gaps = 19/314 (6%)
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D+G +EC+A + AG R + S PPV + P E +V+
Sbjct: 492 SDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVTPGERAVL-T 540
Query: 305 CTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C ++ W N + L E RI N S+ +K+V+ +DAG Y C V + G
Sbjct: 541 CLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSS 600
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
+ASV L V PP V+P NQ+ G V C A G PKP I W N + + + +
Sbjct: 601 AASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRM 660
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ D L + D IY C A N G + ++ TL +E P +V++ E + A
Sbjct: 661 TSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVVQSELLVALG 716
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRYECSAF 541
+ +V M C+ +PP + W K + + I ++G L I+ D G Y C A
Sbjct: 717 DITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAI 775
Query: 542 NDYGRDTASVFLTV 555
N+ GR T + L V
Sbjct: 776 NEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 82/350 (23%), Positives = 145/350 (41%), Gaps = 22/350 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE--DMDAFKETSVQMPCEIESVPPA 498
Y C A N G E + + + +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKNYNVNI----WVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPP 2226
Query: 499 SIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2483 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2542
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2543 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2595
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2596 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2655
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2656 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2715
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2716 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2771
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2772 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2831
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2832 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2858
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4317
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 4318 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSNWIEPLGGNA 4367
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4368 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4427
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4428 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4487
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4488 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4518
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/209 (29%), Positives = 90/209 (43%), Gaps = 5/209 (2%)
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKG 399
I V SD G Y C + G A +V+ PP I VP N T G+ TC
Sbjct: 486 IAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLIIS 545
Query: 400 TPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
++ W RN + + + + N +L L V +D YHC ++GG AS
Sbjct: 546 AVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF 605
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
LT+++ PP++ + P++ + V + C P I W + IV R +T
Sbjct: 606 LTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT 661
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L I+N + D G Y C A N G D
Sbjct: 662 SDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4347 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4406 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4455
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4456 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4514
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4515 MGSVLVRVPVIVQVHGGF 4532
Score = 45.2 bits (102), Expect = 0.002
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + +L
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 842 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 901
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 902 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 950
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 951 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 1010
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 1011 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 1070
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 1071 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 1126
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 1127 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQITFVQPGDAGHYTC 1186
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 1187 MAANVAGSSSTSTKLTV 1203
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 665 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 723
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 724 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 772
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 773 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 832
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 833 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 892
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 893 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 948
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 949 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 1008
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 1009 NAAGSAHRHVTLHVHE 1024
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 555 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 614
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 615 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 664
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 665 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 724
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 725 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 784
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 785 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 840
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 841 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 900
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 901 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 932
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 751 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 810
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 811 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 860
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 861 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 919
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 920 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 979
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 980 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 1035
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 1036 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 1095
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 1096 CVAQNPAGTALGKIKLNVQ 1114
Score = 153 bits (372), Expect = 3e-36
Identities = 108/383 (28%), Positives = 168/383 (43%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 1023 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 1078
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 1079 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 1127
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 1128 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQITFVQPGDAGHYTCM 1187
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 1188 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 1247
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 1248 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 1303
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 1304 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 1362
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A F+ VK+
Sbjct: 1363 TYVCTAENSVGFVKAIGFVYVKE 1385
Score = 151 bits (365), Expect = 2e-35
Identities = 110/391 (28%), Positives = 170/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 1185 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 1240
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 1241 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 1295
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 1296 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 1349
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A + V PP F P++ +G N
Sbjct: 1350 -ELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPLGGNAILN 1408
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 1409 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 1467
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 1468 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 1523
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 1524 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 1554
Score = 142 bits (345), Expect = 6e-33
Identities = 104/358 (29%), Positives = 165/358 (46%), Gaps = 26/358 (7%)
Query: 202 TCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKA 261
TC +G P P++ WL++ + I LN N + TL + A +D G + C+A N AG++
Sbjct: 23 TCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGES 82
Query: 262 HSK-PAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
K + V ++H S + +S R TSV + + P P + WY N
Sbjct: 83 KKKFSLTVYVPPSIKDHDSES----LSVVNVR----EGTSVSLEXESNAVPPPVITWYKN 134
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVV 379
G + + + + +G +L IK + SD G Y C+ N+ G+ + L V PPS I
Sbjct: 135 GRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEG 193
Query: 380 PTNQTAI--IGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEV 434
P + + I + V TC A G P P+I W +N + + +L +LS ++ L +
Sbjct: 194 PEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARS 252
Query: 435 TRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEI 492
D Y C A N G + L+++ +PP + P D+ +V++ C
Sbjct: 253 QHSDSGNYTCIASNMEGKAQKYYFLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNA 308
Query: 493 ESVPPASIDWRKDGSRIV--EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
+P I W KDG I E +RI ++ GS L I +DTG+Y C A N G +
Sbjct: 309 NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 366
Score = 138 bits (335), Expect = 9e-32
Identities = 108/397 (27%), Positives = 178/397 (44%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 1103 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 1158
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 1159 ESIRQRVLSSGSLQITFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 1208
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 1209 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 1266
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 1267 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 1326
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A + ++
Sbjct: 1327 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVK 1384
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 1385 EPPVFKGDYPSHWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 1438
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 1439 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 1475
Score = 134 bits (324), Expect = 2e-30
Identities = 95/360 (26%), Positives = 160/360 (44%), Gaps = 21/360 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C ATG P P+I WL++ +PL+ + + + + A +D ++ C+A N AG
Sbjct: 402 CRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG--- 458
Query: 263 SKPAKMIVRRKAEEHKSPAPP-VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
V K + APP + S + + +S C G P P +AW +G
Sbjct: 459 -------VDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDG 511
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + L+ + + +G +L + + D+G YTC N G++S L+V PP
Sbjct: 512 QPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSE 571
Query: 381 TNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
++ + I+ + + TC A G P P + W ++ LP T + + L + +D
Sbjct: 572 EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVED 631
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI--VLKPEDMDAFKETSVQMPCEIESVP 496
Y C A + G + ++ + +PP I +P D+ + V + C+ ++VP
Sbjct: 632 TGRYTCLASSPAGDDDKEYLVRVH----VPPNIAGTDEPRDITVLRNRQVTLECKSDAVP 687
Query: 497 PASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
P I W ++G R+ R+ I G L I N + DT Y C A N G+ T LTV
Sbjct: 688 PPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTV 747
Score = 130 bits (314), Expect = 3e-29
Identities = 103/386 (26%), Positives = 164/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 189 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQ 248
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 249 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 300
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 301 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 359
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQT---AIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ ++ ++ C+A GTP P I W +N +
Sbjct: 360 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGL 419
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 420 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 475
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 476 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 535
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 536 TEDSGKYTCIASNEAGEVSKHFILKV 561
Score = 127 bits (306), Expect = 3e-28
Identities = 100/376 (26%), Positives = 155/376 (41%), Gaps = 25/376 (6%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLF 250
V V G + + P P I W ++ +I + + + D L + +A +D G +
Sbjct: 107 VNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQY 166
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKR-FAKINETSVMFDCTATG 309
C A NVAG R H + P + P++ + V C ATG
Sbjct: 167 VCRAINVAG-----------RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATG 215
Query: 310 FPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
P P +AW N +R+ ++ + IL + I Q+SD+G YTC N+ GK
Sbjct: 216 IPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 275
Query: 367 PLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN--TVILPITGNLVL 422
L + PPS +P++ + ++G+NV C A G P P I+W ++ + T + +
Sbjct: 276 FLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRV 335
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDA 480
S + L + D Y C A N G E + L V + P K E +
Sbjct: 336 SANGSTLNIYGALTSDTGKYTCVATNPAG--EEDRIFNL-NVYVTPTIRGNKDEAEKLMT 392
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECS 539
+TS+ + C PP I+W K+G + I + G +I I V+D Y C
Sbjct: 393 LVDTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCV 452
Query: 540 AFNDYGRDTASVFLTV 555
A N G D L V
Sbjct: 453 ASNRAGVDNKHYNLQV 468
Score = 114 bits (275), Expect = 2e-24
Identities = 75/273 (27%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 1298 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 1355
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K I +E PPVF + + +
Sbjct: 1356 VSKEDSGTYVCTAENSVGFV-----KAIGFVYVKE-----PPVFKGDYPSHWIEPLGGNA 1405
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 1406 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 1465
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 1466 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 1525
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 1526 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 1556
Score = 103 bits (246), Expect = 6e-21
Identities = 74/286 (25%), Positives = 125/286 (43%), Gaps = 17/286 (5%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-I 340
PP + + + + C +GFP P ++W N + + LN ++ G L I
Sbjct: 1 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQI 60
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII----GDNVWFTCK 396
+ SD G YTC N G+ L V PPS + +++ G +V +
Sbjct: 61 IRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXE 120
Query: 397 AKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS 456
+ P P I WY+N ++ + ++ + D Q L + + D Y CRA N G + +
Sbjct: 121 SNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKN 180
Query: 457 AVLTLEQVEIIPPRIVLKPEDMDAFKET---SVQMPCEIESVPPASIDWRKDGSRIVEDD 513
L + +PP I + + + ET V + C+ +PP +I W K+ RI D
Sbjct: 181 FHLNV----YVPPSI--EGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSD 234
Query: 514 RISITVI--GS-LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ + ++ GS L I +D+G Y C A N G+ FL+++
Sbjct: 235 SLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQ 280
Score = 79.0 bits (186), Expect = 1e-13
Identities = 50/198 (25%), Positives = 85/198 (42%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P+ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 1385 EPPVFKGDYPSHWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 1443
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 1444 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 1493
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 1494 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 1552
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 1553 MGSVLVRVPVIVQVHGGF 1570
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 159 bits (385), Expect = 8e-38
Identities = 105/377 (27%), Positives = 159/377 (42%), Gaps = 18/377 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL--NENRYEIFDNGTLMV 239
P P ++ V C ATG P P I W ++ ++ + N+N Y + +G+L++
Sbjct: 3805 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3864
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D +EC N AG + + V+ PP P F
Sbjct: 3865 ISPSVDDTATYECTVTNGAGD-DKRTVDLTVQ---------VPPSIADEPTD-FLVTKHA 3913
Query: 300 SVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ CTA+G P P + W NG R+L + + +G+I I Q + AG YTC N
Sbjct: 3914 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3973
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G V L V PP P+ I+ + + C+A GTP P I W + + + +G
Sbjct: 3974 AGSAHRHVTLHVHEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSG 4033
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + R+D Y C A+N G L ++ +I P + ++
Sbjct: 4034 RNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVISPHL----KEY 4089
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + + CE + +PP I W KDG IVE R + GSL I V D G Y C
Sbjct: 4090 VIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTC 4149
Query: 539 SAFNDYGRDTASVFLTV 555
A N G + S LTV
Sbjct: 4150 MAANVAGSSSTSTKLTV 4166
Score = 158 bits (384), Expect = 1e-37
Identities = 115/389 (29%), Positives = 179/389 (46%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM 238
+ P PN+V V+ GE AV TC+ + W R+ + L E R N +L
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ ND G + CM + G S A + + +E P V V + F +E
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGG---SSAASVFLT--VQE----PPKVTVMPKNQSFTGGSE 628
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
S+M C+ATG+PKP +AW N ++ + R + +G++ IKN DAG+Y C N
Sbjct: 629 VSIM--CSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNS 686
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G + L P +VV + +GD CK G P P +KW++ + L +
Sbjct: 687 AGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 419 NLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
L++ D L ++ T+D DA Y C A N+ G A+ +TL+ PP + +P D
Sbjct: 747 FLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG--RATGKITLDVGS--PPVFIQEPAD 801
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRK-DG----SRIVEDDRISITVIGSLIIRNVSVTD 532
+ ++V +PC ++ P +I WR+ D SR IS G+L I N+ +D
Sbjct: 802 VSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASD 861
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G Y C A N +G+ + +TV + P
Sbjct: 862 KGTYICEAENQFGKIQSETTVTVTGLVAP 890
Score = 158 bits (384), Expect = 1e-37
Identities = 110/376 (29%), Positives = 163/376 (43%), Gaps = 21/376 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT-LMVHEANEN 245
EP D+ V C + P P I WLR+ E + R I G L ++ A+
Sbjct: 3628 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATP-RVRILSGGRYLQINNADLG 3686
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D + C+A N+AGK ++ + V PP PQ +N+++V+ +C
Sbjct: 3687 DTANYTCVASNIAGKT-TREFILTVN---------VPPNIKGGPQSLVILLNKSTVL-EC 3735
Query: 306 TATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
A G P P + W +G + N R + NG + I++ +D G Y C N G
Sbjct: 3736 IAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRR 3795
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI--TGNLVL 422
+ L+V PPS PTN T I+ C+A G PKPSI W +N +L + N
Sbjct: 3796 RIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYR 3855
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
+ +L ++ + DD A Y C N G + + LT++ +PP I +P D K
Sbjct: 3856 LLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ----VPPSIADEPTDFLVTK 3911
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITVIGSLIIRNVSVTDTGRYECSAF 541
+ C VP SI W K+G R++ D I G++ I + GRY C A
Sbjct: 3912 HAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVAR 3971
Query: 542 NDYGRDTASVFLTVKD 557
N G V L V +
Sbjct: 3972 NAAGSAHRHVTLHVHE 3987
Score = 156 bits (379), Expect = 4e-37
Identities = 107/362 (29%), Positives = 166/362 (45%), Gaps = 21/362 (5%)
Query: 203 CVATGEPAPEILWLRD-SEVIPLNENRYEIFDNGT-LMVHEANENDDGLFECMAKNVAGK 260
C ++G P P ++W + S V+ + R I G L + A ++D L+ C+A NVAG
Sbjct: 2219 CESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGT 2278
Query: 261 AHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFN 320
A + + R + P + T K S+ +C G P P V W +
Sbjct: 2279 AKKEYNLQVYIRPTITNSGSHPTEIIVTRGK--------SISLECEVQGIPPPTVTWMKD 2330
Query: 321 GERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV- 378
G ++ + + + G IL +KN+ SD G Y C N+ G L V APPS I
Sbjct: 2331 GHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGN 2390
Query: 379 --VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTR 436
P N + + ++V TC+A G P PS W+++ + ++ ++ + + L L++ T
Sbjct: 2391 HRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQTTM 2450
Query: 437 DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIES 494
+D Y C N G E + L ++PP IV + ED+ ++ SV + CE+
Sbjct: 2451 EDAGQYTCVVRNAAG--EERKIFGLS--VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTG 2506
Query: 495 VPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P I W KDG + ED+ I G + I NV V TGRY C A + G + S L
Sbjct: 2507 NPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSL 2566
Query: 554 TV 555
V
Sbjct: 2567 NV 2568
Score = 155 bits (377), Expect = 8e-37
Identities = 109/392 (27%), Positives = 165/392 (42%), Gaps = 22/392 (5%)
Query: 173 KHHDLPCQQPQF---ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH L +P E ++ V TC+A+G PAP++ W++D +P +
Sbjct: 3518 KHFILKVLEPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3577
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ L + A D G + C+A + AG + +VR H PP T
Sbjct: 3578 TLGGGEVLRISTAQVEDTGRYTCLASSPAG---DDDKEYLVR----VH---VPPNIAGTD 3627
Query: 290 QKR-FAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSD 347
+ R + V +C + P P + W NGER+ R+ + G L I N D
Sbjct: 3628 EPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGD 3687
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
YTC NI GK + L V PP+ P + ++ + C A+G P P I W
Sbjct: 3688 TANYTCVASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITW 3747
Query: 408 YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
++ +L +N L + D Y C A N G L + +
Sbjct: 3748 RKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVH----V 3803
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVI--GSLI 524
PP I P +M + CE +P SI+WRK+G + V+ ++ S ++ GSL+
Sbjct: 3804 PPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLV 3863
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I + SV DT YEC+ N G D +V LTV+
Sbjct: 3864 IISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3895
Score = 155 bits (375), Expect = 1e-36
Identities = 108/383 (28%), Positives = 169/383 (44%), Gaps = 20/383 (5%)
Query: 175 HDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN 234
H+ P QPQ P+++ V + C ATG P+P I W ++ + + + + +
Sbjct: 3986 HEPPVIQPQ----PSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPS 4041
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
G L + A D G + C+A+N AG A K K+ V+ PPV +S K +
Sbjct: 4042 GGLQISRAVREDAGTYMCVAQNPAGTALGK-IKLNVQ---------VPPV-ISPHLKEYV 4090
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
+ + C A G P P + W+ +G ++ + R + +GS+ I VQ DAG YTC
Sbjct: 4091 IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCM 4150
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N+ G S S L V PP + T C A G P P+I W ++ V+L
Sbjct: 4151 AANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL 4210
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
++ L L V +D Y C A N G + LT V ++P L
Sbjct: 4211 ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT---VHVLPTFTEL- 4266
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
P D+ K +++ C+ +P + W + + I+ S+ L+I VS D+G
Sbjct: 4267 PGDVSLNKGEQLRLSCKATGIPLPKLTWTFN-NNIIPAHFDSVNGHSELVIERVSKEDSG 4325
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C+A N G A+ F+ VK+
Sbjct: 4326 TYVCTAENSVGFVKATGFVYVKE 4348
Score = 154 bits (373), Expect = 2e-36
Identities = 111/391 (28%), Positives = 171/391 (43%), Gaps = 23/391 (5%)
Query: 157 TCYQPASVTGTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW 215
TC A+V G+S + K +P P+ S V+ A+ CVA G P P I W
Sbjct: 4148 TC-MAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAILPCVADGIPTPAINW 4203
Query: 216 LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+D+ ++ +Y G L++ D G + C+A N AG+ + + V
Sbjct: 4204 KKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGE-DTHTVSLTVH---- 4258
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
P F P E + C ATG P P + W FN + + + H+
Sbjct: 4259 -----VLPTFTELPGDVSLNKGE-QLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHS 4312
Query: 336 GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIV-VPTNQTAIIGDNVWFT 394
++I+ V D+G Y C EN G + A+ + V PP F P+N +G N
Sbjct: 4313 -ELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIEPLGGNAILN 4371
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIE 454
C+ KG P P+I+W R V + I+ + + N +L + +D Y C A N+ G++E
Sbjct: 4372 CEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4430
Query: 455 ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR 514
S LTL+ PP I L+P + + + C+ P +I W + G I DDR
Sbjct: 4431 RSMSLTLQS----PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDR 4486
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
+++ SL I + DT +EC A N G
Sbjct: 4487 VNVLSNNSLYIADAQKEDTSEFECVARNLMG 4517
Score = 153 bits (372), Expect = 3e-36
Identities = 105/379 (27%), Positives = 155/379 (40%), Gaps = 19/379 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + P + + ++ V C+A G P P I W +D V+ N RY I +NG L +
Sbjct: 3714 PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQS 3773
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A+ D G + CMA N AG R+ + + PP P +N +
Sbjct: 3774 AHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTT 3823
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C ATG PKP + W NG + +++ L +GS++I + D Y C V N
Sbjct: 3824 L-ACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNG 3882
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
G +V L V PPS PT+ TC A G P PSI W +N + L G
Sbjct: 3883 AGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRG 3942
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ + + +L + Y C A N G L + + PP I +P ++
Sbjct: 3943 DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHE----PPVIQPQPSEL 3998
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-ISITVIGSLIIRNVSVTDTGRYE 537
+ +PCE P I W+K+G + R ++ G L I D G Y
Sbjct: 3999 HVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYM 4058
Query: 538 CSAFNDYGRDTASVFLTVK 556
C A N G + L V+
Sbjct: 4059 CVAQNPAGTALGKIKLNVQ 4077
Score = 152 bits (369), Expect = 7e-36
Identities = 108/389 (27%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 1142
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 1143 SDSGMYLCVATNIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 1191
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 1192 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 1309
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + ++ L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 1310 REPGISILEEGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 1365
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 1366 QVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPED 1425
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 1426 AGRYSCKAINIAG--TSQKYFNI-DVLVP 1451
Score = 151 bits (367), Expect = 1e-35
Identities = 104/381 (27%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D ++I + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 1756 CHVTGSPPPTIMWLKDGQLID-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 1813
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H K ++ V PP S+ + V C A G P P + W +
Sbjct: 1814 HKKEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 1864
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 1865 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 1924
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 1925 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQIS 1984
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 2040
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAV 2121
Score = 149 bits (362), Expect = 5e-35
Identities = 97/376 (25%), Positives = 158/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P +V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 1460 PKEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 1519
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 1520 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECK 1570
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ C A G P P + W ++ V + N +
Sbjct: 1631 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECNAAGNPSPILTWLKDGVPVKANDNFRI 1690
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 1746
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG I E D I + G L+I V++TG Y C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 1807 AANTAGDHKKEFEVTV 1822
Score = 148 bits (359), Expect = 1e-34
Identities = 96/382 (25%), Positives = 170/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 1284
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSILIKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E IL+ ++I +V D G Y C N
Sbjct: 1285 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP +N + ++ C+ +GTP P I WY++ V + +
Sbjct: 1345 GTTERKYNLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 1404
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 1405 STIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 1460
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
+++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 1461 KEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 1520
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 1521 GRYQCTVSNAAGKQAKDIKLTI 1542
Score = 148 bits (359), Expect = 1e-34
Identities = 110/405 (27%), Positives = 169/405 (41%), Gaps = 22/405 (5%)
Query: 173 KHHDLPC-QQPQFESEPNDVEVSF--GENAVFTCVATGEPAPEILWLRDSEVIPLNENRY 229
KH++L P ++ E++ G + C+ G PAP + WLRD + + L+ +
Sbjct: 3425 KHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLT 3484
Query: 230 EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
L + +A D G + C+A N AG+ +K + + E P + S
Sbjct: 3485 VSTHGMVLQLLKAETEDSGKYTCIASNEAGEV----SKHFILKVLE-----PPHINGSEE 3535
Query: 290 QKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDA 348
+ + I + C A+G P P + W +G + +++ G +L I Q D
Sbjct: 3536 HEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDT 3595
Query: 349 GVYTCQVENIHGKISASVPLEVTAPPSFIVV--PTNQTAIIGDNVWFTCKAKGTPKPSIK 406
G YTC + G + V PP+ P + T + V CK+ P P I
Sbjct: 3596 GRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVIT 3655
Query: 407 WYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEI 466
W RN L T + + + L + D A Y C A N G +LT+
Sbjct: 3656 WLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN---- 3711
Query: 467 IPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD-RISITVIGSLII 525
+PP I P+ + S + C E VP I WRKDG+ + + R SI G L I
Sbjct: 3712 VPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHI 3771
Query: 526 RNVSVTDTGRYECSAFNDYGRDTASVFLT--VKDNLLPGDAYVNI 568
++ VTDTGRY C A N G D + L V ++ PG + +
Sbjct: 3772 QSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTV 3816
Score = 148 bits (358), Expect = 2e-34
Identities = 112/395 (28%), Positives = 179/395 (45%), Gaps = 28/395 (7%)
Query: 167 TSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVF--TCVATGEPAPEILWLRDSEVIPL 224
T+ +A K+ +L P P ++ N TC +G P P++ WL++ + I L
Sbjct: 2949 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKL 3008
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
N N + TL + A +D G + C+A N AG++ K + V ++H S +
Sbjct: 3009 NTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSES-- 3066
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKN 342
+S R TSV +C + P P + WY NG + + + + +G +L IK
Sbjct: 3067 --LSVVNVR----EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKK 3120
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGT 400
+ SD G Y C+ N+ G+ + L V PPS I P + + I + V TC A G
Sbjct: 3121 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS-IEGPEREVIVETISNPVTLTCDATGI 3179
Query: 401 PKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P+I W +N + + +L +LS ++ L + D Y C A N G +
Sbjct: 3180 PPPTIAWLKNYKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQKYY 3238
Query: 458 VLTLEQVEIIPPRIVLK--PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDD 513
L+++ +PP + P D+ +V++ C +P I W KDG I E +
Sbjct: 3239 FLSIQ----VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE 3294
Query: 514 RISITVIGS-LIIRNVSVTDTGRYECSAFNDYGRD 547
RI ++ GS L I +DTG+Y C A N G +
Sbjct: 3295 RIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3329
Score = 140 bits (338), Expect = 4e-32
Identities = 108/397 (27%), Positives = 179/397 (45%), Gaps = 30/397 (7%)
Query: 166 GTSLAAMKHH-DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
GT+L +K + +P P + ++ + +C A G P P+I W +D I +
Sbjct: 4066 GTALGKIKLNVQVP---PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-V 4121
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
R + +G+L + D G + CMA NVAG + S K+ V PP
Sbjct: 4122 ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSS-STSTKLTVH---------VPPR 4171
Query: 285 FVSTPQKRFAKINETS-VMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSILIKN 342
ST + +NE S + C A G P P + W + + L + + G ++++N
Sbjct: 4172 IRST--EGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILEN 4229
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V D+G YTC N G+ + +V L V P+F +P + + G+ + +CKA G P
Sbjct: 4230 VVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPL 4289
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P + W N I+P + V + + L + V+++D Y C AEN G ++A+ + ++
Sbjct: 4290 PKLTWTFNNNIIPAHFDSV--NGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVK 4347
Query: 463 QVEIIP---PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
+ + P ++P +A + CE++ P +I W + G I RI
Sbjct: 4348 EPPVFKGDYPSNWIEPLGGNAI------LNCEVKGDPTPTIQWNRKGVDIEISHRIRQLG 4401
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
GSL I D G Y C A N+ G S+ LT++
Sbjct: 4402 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4438
Score = 139 bits (337), Expect = 5e-32
Identities = 99/381 (25%), Positives = 169/381 (44%), Gaps = 29/381 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V V ++A+ C+++G PAP W +D + + L ++ ++ NG L + D
Sbjct: 2880 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQITD 2938
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C+A+N AG A +K PP + + + + C
Sbjct: 2939 IGRYVCVAENTAGSA----------KKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCE 2988
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
+GFP P ++W N + + LN ++ G L I + SD G YTC N G+
Sbjct: 2989 VSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKK 3048
Query: 366 VPLEVTAPPSFIVVPTNQTAII----GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
L V PPS + +++ G +V C++ P P I WY+N ++ + ++
Sbjct: 3049 FSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVE 3108
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D Q L + + D Y CRA N G + + L + +PP I + + +
Sbjct: 3109 ILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV----YVPPSI--EGPEREVI 3162
Query: 482 KET---SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI--GS-LIIRNVSVTDTGR 535
ET V + C+ +PP +I W K+ RI D + + ++ GS L I +D+G
Sbjct: 3163 VETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3222
Query: 536 YECSAFNDYGRDTASVFLTVK 556
Y C A N G+ FL+++
Sbjct: 3223 YTCIASNMEGKAQKYYFLSIQ 3243
Score = 139 bits (336), Expect = 7e-32
Identities = 97/384 (25%), Positives = 171/384 (44%), Gaps = 24/384 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P N V V C A G PAP + WL+D + N ++ G ++
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 2071
Query: 242 ANE-NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ + +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 2072 STQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 2120
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 2180
Query: 360 GKI-SASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR--NTVIL 414
GK + + + PP+ T T I G+ + C++ G P P++ W + + V+
Sbjct: 2181 GKTEKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2240
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP--PRIV 472
G + + + L + + D A+Y C A N G + L QV I P
Sbjct: 2241 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNL---QVYIRPTITNSG 2297
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVT 531
P ++ + S+ + CE++ +PP ++ W KDG +++ + I G ++ ++N+ V+
Sbjct: 2298 SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVS 2357
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
DTGRY C A N G L+V
Sbjct: 2358 DTGRYVCVAVNVAGMTDKKYDLSV 2381
Score = 139 bits (336), Expect = 7e-32
Identities = 104/377 (27%), Positives = 159/377 (42%), Gaps = 32/377 (8%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
P ++ V + TC A+G P P W +D + L+ N I G ++ + + D
Sbjct: 2394 PENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLS-NSVRILSGGRMLRLMQTTMED 2452
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDC 305
G + C+ +N AG+ RK PP V K+ E SV C
Sbjct: 2453 AGQYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTC 2502
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISA 364
TG P P + W+ +G+ + +E + G L I NVQ G YTC + G S
Sbjct: 2503 EVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSR 2562
Query: 365 SVPLEVTAPPSFIVV-----PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
S L V P+ V P + T I+ C+A P +I W+++ L N
Sbjct: 2563 SFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2622
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-------- 471
+ + + L +L D+ Y C A N+ G + E IPP I
Sbjct: 2623 IRILPGGRTLQILNAQEDNAGRYSCVATNEAG----EMIKHYEVKVYIPPIINKGDLWGP 2678
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSV 530
L P+++ ++ + CE ++P AS+ W KDG + DD ++I G +L I+ +
Sbjct: 2679 GLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQI 2738
Query: 531 TDTGRYECSAFNDYGRD 547
+DTGRY C A N G D
Sbjct: 2739 SDTGRYTCVASNIAGED 2755
Score = 133 bits (321), Expect = 5e-30
Identities = 96/355 (27%), Positives = 153/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 1002 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAK 1061
Query: 263 SKPAKMIVRRKAE----EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + R S PV +S + V C P P + W
Sbjct: 1062 RKVQLTVYVRPRVFGDLRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 1114
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 1234
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 1235 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 1290
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 1291 KGTPKPTIKWLHNGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 132 bits (318), Expect = 1e-29
Identities = 106/388 (27%), Positives = 159/388 (40%), Gaps = 27/388 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 903
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 904 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 964 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 1023
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV---- 472
+ + + +L ++ ++ Y C A N G + LT+ + PR+
Sbjct: 1024 SSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTV----YVRPRVFGDLR 1079
Query: 473 ----LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRN 527
KP ++ V +PCE++S+PP I W K+ I R + GS+ I
Sbjct: 1080 GLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITE 1139
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
+D+G Y C A N G T +V L V
Sbjct: 1140 TRTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 128 bits (308), Expect = 2e-28
Identities = 102/386 (26%), Positives = 163/386 (42%), Gaps = 25/386 (6%)
Query: 182 PQFESEPNDVEVSFGENAV-FTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGT-LM 238
P E +V V N V TC ATG P P I WL++ + I +++ I G+ L
Sbjct: 3152 PSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQ 3211
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +D G + C+A N+ GKA I + P P + E
Sbjct: 3212 IARSQHSDSGNYTCIASNMEGKAQKYYFLSI--------QVPPSVAGAEIPSDVSVLLGE 3263
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+V C A G P P + W +G+ + E RI + NGS L I SD G YTC
Sbjct: 3264 -NVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVA 3322
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAI---IGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G+ L V P+ + + ++ C+ GTP P I W +N +
Sbjct: 3323 TNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIECRXTGTPPPQINWLKNGL 3382
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI- 471
LP++ ++ L Q + ++ D A+Y C A N G+ L + PP +
Sbjct: 3383 PLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQV----FAPPNMD 3438
Query: 472 -VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVS 529
+ E++ K +S M C + P S+ W +DG + D ++++ G ++ +
Sbjct: 3439 NSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAE 3498
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
D+G+Y C A N+ G + L V
Sbjct: 3499 TEDSGKYTCIASNEAGEVSKHFILKV 3524
Score = 124 bits (300), Expect = 2e-27
Identities = 91/365 (24%), Positives = 151/365 (41%), Gaps = 23/365 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + ++V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 1364 KEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP 1423
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP-QKRFAKINETSVMF 303
D G + C A N+AG + +K PP + T K + + V
Sbjct: 1424 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPKEVSVVLNRDVAL 1473
Query: 304 DCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGK 361
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N GK
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGK 1533
Query: 362 ISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ + L + PPS V T+ + +I + CK +G P P+I WY++ + +
Sbjct: 1534 QAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWYKDGQPIMSSSQ 1593
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKPE 476
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATPL 1649
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGR 535
+ S+ + C P + W KDG + +D I G L I + D G+
Sbjct: 1650 NKQVVIAHSLTLECNAAGNPSPILTWLKDGVPVKANDNFRIEAGGKKLEIMSAQEIDRGQ 1709
Query: 536 YECSA 540
Y C A
Sbjct: 1710 YICVA 1714
Score = 119 bits (286), Expect = 8e-26
Identities = 93/377 (24%), Positives = 153/377 (40%), Gaps = 14/377 (3%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANEND 246
P +V++ C A P+ + W +D + + +++ I NG TL + EA +D
Sbjct: 2682 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLK-SDDHVNIAANGHTLQIKEAQISD 2740
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK--INETSVMFD 304
G + C+A N+AG+ + ++ K + T + AK I +
Sbjct: 2741 TGRYTCVASNIAGE-DELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLY 2799
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKIS 363
C P P + WY +G + ++++++ G +L I + DAG YTC N G+ S
Sbjct: 2800 CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDS 2859
Query: 364 ASVPLEVTAPP----SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
+ V PP + +P T ++ + C + G+P P W ++ L +
Sbjct: 2860 LQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDH 2919
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ + L +L D Y C AEN G A L V + P I K E++
Sbjct: 2920 HKFLSNGRILQILNTQITDIGRYVCVAENTAG--SAKKYFNL-NVHVPPSVIGPKSENLT 2976
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYEC 538
+ + CE+ PP + W K+ I + I G +L I V+D G Y C
Sbjct: 2977 VVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTC 3036
Query: 539 SAFNDYGRDTASVFLTV 555
A N G LTV
Sbjct: 3037 IAINXAGESKKKFSLTV 3053
Score = 117 bits (282), Expect = 2e-25
Identities = 94/323 (29%), Positives = 144/323 (44%), Gaps = 19/323 (5%)
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+L + + +D+G +EC+A + AG R + S PPV + P
Sbjct: 483 SLDIAKVTLSDEGFYECIAVSSAGTG---------RAQTFFDVSEPPPV-IQVPNNVTVT 532
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTC 353
E +V+ C ++ W N + L E RI N S+ +K+V+ +DAG Y C
Sbjct: 533 PGERAVL-TCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHC 591
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
V + G +ASV L V PP V+P NQ+ G V C A G PKP I W N +
Sbjct: 592 MVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMF 651
Query: 414 LPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ + ++ D L + D IY C A N G + ++ TL +E P +V+
Sbjct: 652 IVGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASNSAGTDKQNS--TLRYIE-APKLMVV 707
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTD 532
+ E + A + +V M C+ +PP + W K + + I ++G L I+ D
Sbjct: 708 QSELLVALGDITV-MECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLD 766
Query: 533 TGRYECSAFNDYGRDTASVFLTV 555
G Y C A N+ GR T + L V
Sbjct: 767 AGDYTCVAINEAGRATGKITLDV 789
Score = 115 bits (276), Expect = 1e-24
Identities = 93/387 (24%), Positives = 153/387 (39%), Gaps = 34/387 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E+ DV+V ++ TC TG P PEI W +D + + +E + I L +
Sbjct: 2484 ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQV 2543
Query: 245 NDDGLFECMAKNVAG-KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
G + C+A + AG K+ S + V S P V+ I +
Sbjct: 2544 PHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTV-------ILNSPTSL 2596
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A +P + W+ +G + N I IL ++ I N Q +AG Y+C N G++
Sbjct: 2597 VCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEM 2656
Query: 363 SASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
++V PP + P + + + C+A P S+ WY++ L
Sbjct: 2657 IKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL 2716
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-- 472
++ ++ + L + E D Y C A N G E + ++ +PP
Sbjct: 2717 KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ----VPPSFQKL 2772
Query: 473 ----------LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
E D + + CE + PP ++ W KDG + D++ I G
Sbjct: 2773 WEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGR 2832
Query: 523 LI-IRNVSVTDTGRYECSAFNDYGRDT 548
++ I V D GRY C A N+ G D+
Sbjct: 2833 VLQIPRAKVEDAGRYTCVAVNEAGEDS 2859
Score = 115 bits (276), Expect = 1e-24
Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 15/273 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F P DV ++ GE +C ATG P P++ W ++ +IP + + + + L++
Sbjct: 4261 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD--SVNGHSELVIER 4318
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++ D G + C A+N G K + ++ PPVF + + +
Sbjct: 4319 VSKEDSGTYVCTAENSVGFV--KATGFVYVKE--------PPVFKGDYPSNWIEPLGGNA 4368
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C G P P + W G + ++ RI NGS+ I N DAG YTC N G
Sbjct: 4369 ILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGV 4428
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL- 420
+ S+ L + +PP + P G + C+A G P+P+I W R + +
Sbjct: 4429 VERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVN 4488
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
VLS N +L + + ++D + + C A N G +
Sbjct: 4489 VLS--NNSLYIADAQKEDTSEFECVARNLMGSV 4519
Score = 112 bits (270), Expect = 7e-24
Identities = 84/351 (23%), Positives = 144/351 (41%), Gaps = 23/351 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A G P P I W +D+ ++ + + + + + A +D G+++C+A N AG
Sbjct: 1942 CKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE 2001
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGE 322
+ + H +P+ +S A + V +C A G P P + W +G
Sbjct: 2002 -------LFYSLQVHVAPS----ISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS 2050
Query: 323 RM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ N +L + + + Q SD G YTC N G+ + L V PP+ +
Sbjct: 2051 PVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEE 2110
Query: 381 TNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA 440
N + +I V C++ P P++ W ++ L L +S++ L + + D
Sbjct: 2111 QNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG 2170
Query: 441 IYHCRAENDGGMIEASAVLTLEQVEI-IPPRIVLKPE--DMDAFKETSVQMPCEIESVPP 497
Y C A N G E V I +PP I E + + + + CE +PP
Sbjct: 2171 RYTCEATNVAGKTEKKNY----NVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPP 2226
Query: 498 ASIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYG 545
++ W+K GS ++ D + ++ L I +D Y C A N G
Sbjct: 2227 PNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2277
Score = 95.1 bits (226), Expect = 2e-18
Identities = 64/229 (27%), Positives = 100/229 (43%), Gaps = 5/229 (2%)
Query: 320 NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVV 379
NG + +++ + + S+ I V SD G Y C + G A +V+ PP I V
Sbjct: 466 NGVTLGVDQYLKESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQV 525
Query: 380 PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLEVTRDD 438
P N T G+ TC ++ W RN + + + + N +L L V +D
Sbjct: 526 PNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFND 585
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPA 498
YHC ++GG AS LT+++ PP++ + P++ + V + C P
Sbjct: 586 AGEYHCMVSSEGGSSAASVFLTVQE----PPKVTVMPKNQSFTGGSEVSIMCSATGYPKP 641
Query: 499 SIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
I W + IV R +T G+L I+N + D G Y C A N G D
Sbjct: 642 KIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/198 (25%), Positives = 86/198 (43%), Gaps = 13/198 (6%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
+ P F+ + P++ G NA+ C G+P P I W R I ++ +R NG+L
Sbjct: 4348 EPPVFKGDYPSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEIS-HRIRQLGNGSLA 4406
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++ D G + C+A N AG V ++ +PP+ P +
Sbjct: 4407 IYGTVNEDAGDYTCVATNEAG----------VVERSMSLTLQSPPIITLEPVETVINAGG 4456
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
++ +C ATG P+P + W G + ++R+ + N S+ I + Q D + C N+
Sbjct: 4457 -KIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARNL 4515
Query: 359 HGKISASVPLEVTAPPSF 376
G + VP+ V F
Sbjct: 4516 MGSVLVRVPVIVQVHGGF 4533
Score = 46.4 bits (105), Expect = 7e-04
Identities = 26/94 (27%), Positives = 48/94 (51%), Gaps = 3/94 (3%)
Query: 466 IIP--PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
I+P P++ + PE + Q+PC ++S+ P ++ + ++G + D + + SL
Sbjct: 426 IVPDAPKVTM-PEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESASVSL 484
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I V+++D G YEC A + G A F V +
Sbjct: 485 DIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 158 bits (383), Expect = 1e-37
Identities = 113/391 (28%), Positives = 183/391 (46%), Gaps = 31/391 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEIFDNGTL----M 238
F EP D G + + C A EP+P+I W +D + L +++R ++ +G+L +
Sbjct: 55 FLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114
Query: 239 VHEA-NENDDGLFECMAK-NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
VH N+ D+G ++C+A G S+ AK+IV P F S P+
Sbjct: 115 VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA---------GLPRFTSQPEPSSVYA 165
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+++ +C P V W N + +LL++R+I +G ++I N D G+Y C VE
Sbjct: 166 GNNAIL-NCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 357 NIHG-KISASVPLEVTAPPS------FIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
+ K S V L+V P F+ P+ +IG +V C A G P P+IKW +
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 410 NTVILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
N L + LVL +L + +VT DD Y C A+N IEA A LT++
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQA---- 339
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P ++ A + + CE+ P ++ W K+G ++ D I +L +
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDN 558
+ +D G Y+C A ND G A L + ++
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLIILEH 430
Score = 139 bits (336), Expect = 7e-32
Identities = 87/303 (28%), Positives = 145/303 (47%), Gaps = 11/303 (3%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+F S+P V G NA+ C + P + W ++ + + L++ ++ +G L++
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKL-PSGMLVISN 210
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A E D GL+ C+ ++ +S ++ V E VF+ P I + V
Sbjct: 211 ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDL---VFLKQPSPLVRVIGQ-DV 266
Query: 302 MFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ C A+G P P + W N E + +ER++L GS+ I +V DAG Y C +N +
Sbjct: 267 VLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 360 GKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPITG 418
I A L V A P F+ PTN A ++ F C+ G P P++KW +N +++P
Sbjct: 327 ETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY 386
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED 477
++ + NL +L + + D+ Y C AEND G +A A ++ LE + P D
Sbjct: 387 FKIVKE--HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 478 MDA 480
+ A
Sbjct: 445 VVA 447
Score = 70.1 bits (164), Expect = 5e-11
Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 13/201 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP+F +P ++ + VF C TG+P P + W+++ +++ + + ++I L V
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV-IPSDYFKIVKEHNLQVL 398
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
++D+G ++C+A+N G A + A++I+ A P P S P+ A + T
Sbjct: 399 GLVKSDEGFYQCIAENDVGNAQA-GAQLIILEHAPATTGPLP----SAPRDVVASLVSTR 453
Query: 301 VMFDCTATGFPKPH----VAWYFNGERMLLNERI-ILQHNG--SILIKNVQNSDAGVYTC 353
+ T PH F + + ER+ H G + I+N+ + ++
Sbjct: 454 FIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRV 513
Query: 354 QVENIHGKISASVPLEVTAPP 374
+N HG +S PL V P
Sbjct: 514 MAQNKHGSGESSAPLRVETQP 534
Score = 63.7 bits (148), Expect = 4e-09
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 12/184 (6%)
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN--- 419
S + P F+V P + ++ G +V C A P P I+W ++ L + +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRR 101
Query: 420 LVLSDDN---QNLTLLEVTRDDDAIYHCRA--ENDGGMIEASAVLTLEQVEIIPPRIVLK 474
+L D + N+ + + D+ Y C A E+ G +I +A L + + PR +
Sbjct: 102 QLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL----PRFTSQ 157
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
PE + + + CE+ + + W ++ ++ DDR+ G L+I N + D G
Sbjct: 158 PEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGG 217
Query: 535 RYEC 538
Y C
Sbjct: 218 LYRC 221
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 158 bits (383), Expect = 1e-37
Identities = 113/391 (28%), Positives = 183/391 (46%), Gaps = 31/391 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEIFDNGTL----M 238
F EP D G + + C A EP+P+I W +D + L +++R ++ +G+L +
Sbjct: 55 FLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114
Query: 239 VHEA-NENDDGLFECMAK-NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
VH N+ D+G ++C+A G S+ AK+IV P F S P+
Sbjct: 115 VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA---------GLPRFTSQPEPSSVYA 165
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+++ +C P V W N + +LL++R+I +G ++I N D G+Y C VE
Sbjct: 166 GNNAIL-NCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 357 NIHG-KISASVPLEVTAPPS------FIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
+ K S V L+V P F+ P+ +IG +V C A G P P+IKW +
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 410 NTVILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
N L + LVL +L + +VT DD Y C A+N IEA A LT++
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQA---- 339
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P ++ A + + CE+ P ++ W K+G ++ D I +L +
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDN 558
+ +D G Y+C A ND G A L + ++
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLIILEH 430
Score = 139 bits (336), Expect = 7e-32
Identities = 87/303 (28%), Positives = 145/303 (47%), Gaps = 11/303 (3%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+F S+P V G NA+ C + P + W ++ + + L++ ++ +G L++
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKL-PSGMLVISN 210
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A E D GL+ C+ ++ +S ++ V E VF+ P I + V
Sbjct: 211 ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDL---VFLKQPSPLVRVIGQ-DV 266
Query: 302 MFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ C A+G P P + W N E + +ER++L GS+ I +V DAG Y C +N +
Sbjct: 267 VLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 360 GKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPITG 418
I A L V A P F+ PTN A ++ F C+ G P P++KW +N +++P
Sbjct: 327 ETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY 386
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED 477
++ + NL +L + + D+ Y C AEND G +A A ++ LE + P D
Sbjct: 387 FKIVKE--HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 478 MDA 480
+ A
Sbjct: 445 VVA 447
Score = 70.1 bits (164), Expect = 5e-11
Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 13/201 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP+F +P ++ + VF C TG+P P + W+++ +++ + + ++I L V
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV-IPSDYFKIVKEHNLQVL 398
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
++D+G ++C+A+N G A + A++I+ A P P S P+ A + T
Sbjct: 399 GLVKSDEGFYQCIAENDVGNAQA-GAQLIILEHAPATTGPLP----SAPRDVVASLVSTR 453
Query: 301 VMFDCTATGFPKPH----VAWYFNGERMLLNERI-ILQHNG--SILIKNVQNSDAGVYTC 353
+ T PH F + + ER+ H G + I+N+ + ++
Sbjct: 454 FIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRV 513
Query: 354 QVENIHGKISASVPLEVTAPP 374
+N HG +S PL V P
Sbjct: 514 MAQNKHGSGESSAPLRVETQP 534
Score = 63.7 bits (148), Expect = 4e-09
Identities = 44/184 (23%), Positives = 80/184 (43%), Gaps = 12/184 (6%)
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN--- 419
S + P F+V P + ++ G +V C A P P I+W ++ L + +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRR 101
Query: 420 LVLSDDN---QNLTLLEVTRDDDAIYHCRA--ENDGGMIEASAVLTLEQVEIIPPRIVLK 474
+L D + N+ + + D+ Y C A E+ G +I +A L + + PR +
Sbjct: 102 QLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL----PRFTSQ 157
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
PE + + + CE+ + + W ++ ++ DDR+ G L+I N + D G
Sbjct: 158 PEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGG 217
Query: 535 RYEC 538
Y C
Sbjct: 218 LYRC 221
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 157 bits (381), Expect = 2e-37
Identities = 113/391 (28%), Positives = 183/391 (46%), Gaps = 31/391 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEIFDNGTL----M 238
F EP D G + + C A EP+P+I W +D + L +++R ++ +G+L +
Sbjct: 55 FLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNV 114
Query: 239 VHEA-NENDDGLFECMAK-NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
VH N+ D+G ++C+A G S+ AK+IV P F S P+
Sbjct: 115 VHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVA---------GLPRFTSQPEPSSVYA 165
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+++ +C P V W N + +LL++R+I +G ++I N D G+Y C VE
Sbjct: 166 GNGAIL-NCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVE 224
Query: 357 NIHG-KISASVPLEVTAPPS------FIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
+ K S V L+V P F+ P+ +IG +V C A G P P+IKW +
Sbjct: 225 SGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMK 284
Query: 410 NTVILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
N L + LVL +L + +VT DD Y C A+N IEA A LT++
Sbjct: 285 NEEALDTESSERLVLLAGG-SLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQA---- 339
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P ++ A + + CE+ P ++ W K+G ++ D I +L +
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLG 399
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDN 558
+ +D G Y+C A ND G A L + ++
Sbjct: 400 LVKSDEGFYQCIAENDVGNAQAGAQLIILEH 430
Score = 136 bits (330), Expect = 4e-31
Identities = 86/303 (28%), Positives = 144/303 (47%), Gaps = 11/303 (3%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+F S+P V G A+ C + P + W ++ + + L++ ++ +G L++
Sbjct: 152 PRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKL-PSGMLVISN 210
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A E D GL+ C+ ++ +S ++ V E VF+ P I + V
Sbjct: 211 ATEGDGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDL---VFLKQPSPLVRVIGQ-DV 266
Query: 302 MFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ C A+G P P + W N E + +ER++L GS+ I +V DAG Y C +N +
Sbjct: 267 VLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 360 GKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPITG 418
I A L V A P F+ PTN A ++ F C+ G P P++KW +N +++P
Sbjct: 327 ETIEAQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDY 386
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED 477
++ + NL +L + + D+ Y C AEND G +A A ++ LE + P D
Sbjct: 387 FKIVKE--HNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 478 MDA 480
+ A
Sbjct: 445 VVA 447
Score = 70.1 bits (164), Expect = 5e-11
Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 13/201 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP+F +P ++ + VF C TG+P P + W+++ +++ + + ++I L V
Sbjct: 340 QPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV-IPSDYFKIVKEHNLQVL 398
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
++D+G ++C+A+N G A + A++I+ A P P S P+ A + T
Sbjct: 399 GLVKSDEGFYQCIAENDVGNAQA-GAQLIILEHAPATTGPLP----SAPRDVVASLVSTR 453
Query: 301 VMFDCTATGFPKPH----VAWYFNGERMLLNERI-ILQHNG--SILIKNVQNSDAGVYTC 353
+ T PH F + + ER+ H G + I+N+ + ++
Sbjct: 454 FIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRV 513
Query: 354 QVENIHGKISASVPLEVTAPP 374
+N HG +S PL V P
Sbjct: 514 MAQNKHGSGESSAPLRVETQP 534
Score = 63.3 bits (147), Expect = 6e-09
Identities = 44/184 (23%), Positives = 79/184 (42%), Gaps = 12/184 (6%)
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN--- 419
S + P F+V P + ++ G +V C A P P I+W ++ L + +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRR 101
Query: 420 LVLSDDN---QNLTLLEVTRDDDAIYHCRA--ENDGGMIEASAVLTLEQVEIIPPRIVLK 474
+L D + N+ + + D+ Y C A E+ G +I +A L + + PR +
Sbjct: 102 QLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL----PRFTSQ 157
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
PE + + CE+ + + W ++ ++ DDR+ G L+I N + D G
Sbjct: 158 PEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGG 217
Query: 535 RYEC 538
Y C
Sbjct: 218 LYRC 221
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 154 bits (374), Expect = 2e-36
Identities = 98/376 (26%), Positives = 161/376 (42%), Gaps = 21/376 (5%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANEND 246
PN+V V + C G P P+I W +D + + L + E+ D G ++ + A ND
Sbjct: 531 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRND 590
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G ++C N AGK +K K+ + P + + + + + +C
Sbjct: 591 KGRYQCTVSNAAGK-QAKDIKLTIYIP--------PSIKGGNVTTDISVLINSLIKLECE 641
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISAS 365
G P P + WY +G+ ++ + + + G L I Q SD+ YTC V N+ G S
Sbjct: 642 TRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 701
Query: 366 VPLEVTAPPSF---IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
++V PP + P N+ +I ++ CKA G P P + W ++ V + N+ +
Sbjct: 702 FHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRI 761
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDA 480
+ L ++ D Y C A + G E + E ++PP I E
Sbjct: 762 EAGGKKLEIMSAQEIDRGQYICVATSVAGEKE----IKYEVDVLVPPAIEGGDETSYFIV 817
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYECS 539
+++ C + PP +I W KDG + E D I + G L+I V++TG Y C
Sbjct: 818 MVNNLLELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 877
Query: 540 AFNDYGRDTASVFLTV 555
A N G +TV
Sbjct: 878 AANTAGDHKEEFEVTV 893
Score = 153 bits (370), Expect = 5e-36
Identities = 109/389 (28%), Positives = 173/389 (44%), Gaps = 32/389 (8%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ +P ++ V GE C P P I W +++++I R+ +G++ + E
Sbjct: 154 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRT 213
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D G++ C+A N+AG ++ K+ V PP P+ ++ + V
Sbjct: 214 SDSGMYLCVAINIAGNV-TQAVKLNVH---------VPPKIQRGPKHLKVQVGQ-RVDIP 262
Query: 305 CTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKIS 363
C A G P P + W G ML++ E + +G++ I SDAG+YTC NI G
Sbjct: 263 CNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDE 322
Query: 364 ASVPLEVTAPPSF--IVVPTN---QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
+ L V PP+ + P N Q + + F C AKGTPKP+IKW N +TG
Sbjct: 323 TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNG--RELTG 380
Query: 419 ---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + +D L + VT D+ Y C A N+ G E L + +PP I K
Sbjct: 381 REPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----VPPVIKDKE 436
Query: 476 E--DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTD 532
+ ++ + CE+E P I W KD ++ E I G ++ + + D
Sbjct: 437 QVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGRILKLFRATPED 496
Query: 533 TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
GRY C A N G T+ + + D L+P
Sbjct: 497 AGRYSCKAINIAG--TSQKYFNI-DVLVP 522
Score = 149 bits (362), Expect = 5e-35
Identities = 98/382 (25%), Positives = 171/382 (44%), Gaps = 18/382 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P+ + P ++V G+ C A G P P I W + + ++ + +GTL + +
Sbjct: 242 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 301
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
A +D G++ C+A N+AG ++ + E P + +T Q+R A +
Sbjct: 302 ATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP---YNTTFQERVA---NQRI 355
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
F C A G PKP + W NG + E I + +G++L I +V D G Y C N
Sbjct: 356 EFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 415
Query: 360 GKISASVPLEVTAPPSF--IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G L+V PP TN + ++ C+ +GTP P I WY++ V + +
Sbjct: 416 GTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTES 475
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--P 475
+ ++ + L L T +D Y C+A N G + + + ++PP I+ P
Sbjct: 476 STIQTVNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV----LVPPTIIGTNFP 531
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLI-IRNVSVTDT 533
++ V + C+++ P I W KDG + + D + + G ++ ++N D
Sbjct: 532 NEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDK 591
Query: 534 GRYECSAFNDYGRDTASVFLTV 555
GRY+C+ N G+ + LT+
Sbjct: 592 GRYQCTVSNAAGKQAKDIKLTI 613
Score = 149 bits (360), Expect = 9e-35
Identities = 102/381 (26%), Positives = 170/381 (44%), Gaps = 24/381 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C TG P P I+WL+D +++ + ++I NG L++ +A ++ GL+ CMA N AG
Sbjct: 827 CHVTGSPPPTIMWLKDGQLVD-ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGD- 884
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
H + ++ V PP S+ + V C A G P P + W +
Sbjct: 885 HKEEFEVTVH---------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDD 935
Query: 322 ERM-LLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF--I 377
+ + + +Q +G +L I DAG YTC N G+ + L V PPS
Sbjct: 936 QPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDA 995
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
N+T ++ + V CKA G P P I WY++ +L + ++ + Q + +
Sbjct: 996 GKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQIS 1055
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D IY C A N G E L + + P I + V++ CE +P
Sbjct: 1056 DAGIYKCVAINSAGATELFYSLQVH----VAPSISGSNNMVAVVVNNPVRLECEARGIPA 1111
Query: 498 ASIDWRKDGSRIVE-DDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYGRDTASVFLT- 554
S+ W KDGS + + + + G ++ + + ++DTGRY C A N G + L
Sbjct: 1112 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 1171
Query: 555 -VKDNLLPGDAYVNIALTQAM 574
V N++ + V++ ++QA+
Sbjct: 1172 YVPPNIMGEEQNVSVLISQAV 1192
Score = 138 bits (333), Expect = 2e-31
Identities = 92/348 (26%), Positives = 160/348 (45%), Gaps = 19/348 (5%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDDGLFECMAKNVAGKA 261
C+A G P P I WL+D + + + +I +G L + + D G + C+A N AG+
Sbjct: 919 CIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGET 978
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
++ + H P + + + V +C A G P P + WY +
Sbjct: 979 ---------QQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDN 1029
Query: 322 ERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP 380
+ + + + G I+ I++ Q SDAG+Y C N G L+V PS I
Sbjct: 1030 RLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHVAPS-ISGS 1088
Query: 381 TNQTAIIGDN-VWFTCKAKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDD 438
N A++ +N V C+A+G P PS+ W ++ + + + L + + L L D
Sbjct: 1089 NNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISD 1148
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPA 498
Y C A N G + L + +PP I+ + +++ +V++ C+ +++PP
Sbjct: 1149 TGRYTCVAVNAAGEKQRDIDLRV----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPP 1204
Query: 499 SIDWRKDGSRIVEDDRISITVIGSLI-IRNVSVTDTGRYECSAFNDYG 545
++ W KDG +++ +SI+ S++ I + V DTGRY C A N G
Sbjct: 1205 TLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 134 bits (324), Expect = 2e-30
Identities = 97/355 (27%), Positives = 156/355 (43%), Gaps = 23/355 (6%)
Query: 203 CVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAH 262
C A+G P P ++W + E+I + ++ +G+L V + G + C A N AG A
Sbjct: 73 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 132
Query: 263 SKPAKMI-VRRKA---EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
K + VR + + S PV +S + V C P P + W
Sbjct: 133 RKVQLTVYVRPRVFGDQRGLSQDKPVEISV-------LAGEEVTLPCEVKSLPPPIITWA 185
Query: 319 FNGERML-LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI 377
+ + + R +GS+ I + SD+G+Y C NI G ++ +V L V PP
Sbjct: 186 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQ 245
Query: 378 VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRD 437
P + +G V C A+GTP P I W + + + G +S+ + L++ + T
Sbjct: 246 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPS 305
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV-LKPEDMDAFKE----TSVQMPCEI 492
D IY C A N G E L +++ PP + L+P F+E ++ PC
Sbjct: 306 DAGIYTCVATNIAGTDETEITLHVQE----PPTVEDLEPPYNTTFQERVANQRIEFPCPA 361
Query: 493 ESVPPASIDWRKDGSRIV-EDDRISITVIGS-LIIRNVSVTDTGRYECSAFNDYG 545
+ P +I W +G + + ISI G+ L+I +V+ D G Y C A N+ G
Sbjct: 362 KGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 416
Score = 123 bits (297), Expect = 4e-27
Identities = 92/366 (25%), Positives = 153/366 (41%), Gaps = 25/366 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
+ + +V V + C G P+P I+W +D+ + + + + L + A
Sbjct: 435 KEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGRILKLFRATP 494
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST--PQKRFAKINETSVM 302
D G + C A N+AG + +K PP + T P + +N V
Sbjct: 495 EDAGRYSCKAINIAGTS----------QKYFNIDVLVPPTIIGTNFPNEVSVVLNR-DVA 543
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G P P + W+ +G+ + L + + L G +L +KN + +D G Y C V N G
Sbjct: 544 LECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 603
Query: 361 KISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
K + + L + PPS V T+ + +I + C+ +G P P+I WY++ + +
Sbjct: 604 KQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS 663
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI---VLKP 475
+ D Q L + D A Y C N G E S + + +PP I + P
Sbjct: 664 QALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV----YVPPMIEGNLATP 719
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTG 534
+ S+ + C+ P + W KDG + +D I I G L I + D G
Sbjct: 720 LNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRG 779
Query: 535 RYECSA 540
+Y C A
Sbjct: 780 QYICVA 785
Score = 107 bits (257), Expect = 3e-22
Identities = 88/346 (25%), Positives = 142/346 (41%), Gaps = 28/346 (8%)
Query: 224 LNENRY-EIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
L +N Y + +G+L + D G + C+A NVAG ++K ++V H P
Sbjct: 2 LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAG-TNNKTTSVVV------HVLPT- 53
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIK 341
+ Q+ + I V C A+G PKP V W GE + + + +GS+ +
Sbjct: 54 ---IQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVV 110
Query: 342 NVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI--------VVPTNQTAIIGDNVWF 393
+ ++G Y C N G V L V P P + + G+ V
Sbjct: 111 SPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTL 170
Query: 394 TCKAKGTPKPSIKWYRNT-VILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGM 452
C+ K P P I W + T +I P + ++ + E D +Y C A N G
Sbjct: 171 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-SMKITETRTSDSGMYLCVAINIAGN 229
Query: 453 IEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVED 512
+ + L + +PP+I P+ + V +PC + P I W K GS ++ D
Sbjct: 230 VTQAVKLNVH----VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVD 285
Query: 513 DRISIT-VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
++ G+L I + +D G Y C A N G D + L V++
Sbjct: 286 GEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQE 331
Score = 70.1 bits (164), Expect = 5e-11
Identities = 46/181 (25%), Positives = 78/181 (43%), Gaps = 13/181 (7%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VH 240
P N V V C A G PAP + WL+D + N ++ G ++ +
Sbjct: 1083 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALT 1142
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A +D G + C+A N AG+ +++ + + PP + Q I++ +
Sbjct: 1143 SAQISDTGRYTCVAVNAAGE----------KQRDIDLRVYVPPNIMGEEQNVSVLISQ-A 1191
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIH 359
V C + P P + W +G +L + + N S+L I++ Q D G YTC+ N+
Sbjct: 1192 VELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVA 1251
Query: 360 G 360
G
Sbjct: 1252 G 1252
>AF533528-1|AAN04471.1| 255|Homo sapiens thyroid peroxidase isoform
5 protein.
Length = 255
Score = 154 bits (373), Expect = 2e-36
Identities = 82/246 (33%), Positives = 122/246 (49%), Gaps = 8/246 (3%)
Query: 561 PGDAYVNIALTQAMRDVDQAIERTVDQLFKNRSAVVNIGDLYRMTRFPNAPEREVARAAE 620
P ++ V+ L ++ R VD A+ T+ + K R +++ L ++ P +ARAAE
Sbjct: 7 PEESRVSSVLEESKRLVDTAMYATMQRNLKKRG-ILSPAQLLSFSKLPEPTSGVIARAAE 65
Query: 621 IYERTLDKLKEYIQSGKKLSTAEPFNYQSVLSNQHLEVIARLSGCVAHREEKDCSDMCYH 680
I E ++ +K + L T + + LS L +IA +SGC+ + C + C
Sbjct: 66 IMETSIQAMKRKVN----LKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 121
Query: 681 SKYRSLDGSCNNFAHPMWGTSLSGFRRILYPIYENGFSQPIGWNKDLKYNGFTLPSARLX 740
+KYR + G+CNN HP WG S + R L P+YE+GFSQP GWN YNGF LP R
Sbjct: 122 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 181
Query: 741 XXXXXXXXXXXXXXXXXH--MTMQWGQWLDHDLDHALPPVSSQTW-DGVDCKKTCDYAPP 797
+ + M WGQ++DHD+ S + G DC+ TC+ P
Sbjct: 182 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 241
Query: 798 CFPIDV 803
CFPI +
Sbjct: 242 CFPIQI 247
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 152 bits (368), Expect = 9e-36
Identities = 117/398 (29%), Positives = 181/398 (45%), Gaps = 33/398 (8%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLM 238
+P+ E + P V + G C A G P P I+W R D + I R++ NG L
Sbjct: 224 EPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHK--SNGILE 281
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D GL+EC+A+N GK + R + + A P ++ + E
Sbjct: 282 IPNFQQEDAGLYECVAENSRGKN-------VARGQLTFY---AQPNWIQKINDIHVAMEE 331
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+V ++C A G PKP W NGE +L +RI ++ G++ I V SDAG+Y C EN
Sbjct: 332 -NVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ-GTLNITIVNLSDAGMYQCLAENK 389
Query: 359 HGKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILP 415
HG I ++ L V A P F + ++ G V CK K +PKP W + IL
Sbjct: 390 HGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILK 449
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ +S+D NL ++ VT+ D Y C A N G ++ L ++ P R+++ P
Sbjct: 450 ENERITISEDG-NLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKD----PTRVMVPP 504
Query: 476 EDMDAFKETSVQMPCEIESVPPASI--DWRKDGSRIVED------DRIS-ITVIGSLIIR 526
MD S+ +PC++ I W +G I D +R+ G L+IR
Sbjct: 505 SSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIR 564
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDA 564
N+ + G+Y C R +A+ L V+ P +A
Sbjct: 565 NIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEA 602
Score = 136 bits (329), Expect = 5e-31
Identities = 100/370 (27%), Positives = 167/370 (45%), Gaps = 8/370 (2%)
Query: 191 VEVSFGENAVFTCVATGEPAP-EILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL 249
V V G+ V C W+ + + R+ + G L + + ++D G
Sbjct: 132 VSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGN 191
Query: 250 FECMAKNVAG--KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
+ C+ N K P +I+R + P + V P+ +V +C A
Sbjct: 192 YTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYE-PKIEVQFPET-VPTAKGATVKLECFA 249
Query: 308 TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVP 367
G P P + W + + + + NG + I N Q DAG+Y C EN GK A
Sbjct: 250 LGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQ 309
Query: 368 LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQ 427
L A P++I + + +NV++ CKA G PKP+ KW +N L + +
Sbjct: 310 LTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTL 369
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
N+T++ ++ D +Y C AEN G+I ++A L++ V R +LK + V
Sbjct: 370 NITIVNLS--DAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTL-VKVGGEVV 426
Query: 488 MPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
+ C+ ++ P W+K + E++RI+I+ G+L I NV+ +D G Y C A N +G
Sbjct: 427 IECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTA 486
Query: 548 TASVFLTVKD 557
+++ L VKD
Sbjct: 487 SSTGNLVVKD 496
Score = 104 bits (249), Expect = 2e-21
Identities = 107/386 (27%), Positives = 151/386 (39%), Gaps = 42/386 (10%)
Query: 182 PQFESEPNDVEV---SFGENAVFTCVATGEPAPEILW-LRDSEVIPLNENRYEIFDNGTL 237
P F EP+ V S + C G P P I W L ++V + RY + + G+L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVE-GSL 84
Query: 238 MVHEANENDD-GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+++ N+ D G ++C A N G S+ AK+ V V Q
Sbjct: 85 LINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQ------ 138
Query: 297 NETSVMFDCTATGFPKPH-----VAWYFNGERMLL-NERIILQHNGSILIKNVQNSDAGV 350
++ C P PH AW FN N R + Q G++ I V+ SD G
Sbjct: 139 ---GMVLLCG----PPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGN 191
Query: 351 YTCQVENI---HGKISASVPLEVT--------APPSFIVVPTNQTAIIGDNVWFTCKAKG 399
YTC V N H + PL + P + P G V C A G
Sbjct: 192 YTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALG 251
Query: 400 TPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
P P+I W R PI N L + ++D +Y C AEN G A L
Sbjct: 252 NPVPTIIW-RRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQL 310
Query: 460 TLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
T P + K D+ E +V C+ P + W K+G ++ DRI I
Sbjct: 311 TF----YAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ 366
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYG 545
G+L I V+++D G Y+C A N +G
Sbjct: 367 -GTLNITIVNLSDAGMYQCLAENKHG 391
Score = 70.5 bits (165), Expect = 4e-11
Identities = 77/288 (26%), Positives = 114/288 (39%), Gaps = 18/288 (6%)
Query: 283 PVFVSTPQKRFAKIN--ETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQ-HNGSIL 339
P+F+ P ++ E V +C G PKPH+ W NG + GS+L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 340 IKNV-QNSDAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTC 395
I N + DAG Y C N G I S L+ +F T T + G + C
Sbjct: 86 INNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNF-KTRTRSTVSVRRGQGMVLLC 144
Query: 396 -KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN---DGG 451
+ + S W N +S + NL + +V + D Y C N +
Sbjct: 145 GPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHK 204
Query: 452 MIEASAVLTLEQVEII---PPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK-DG 506
++ L L ++ P+I ++ PE + K +V++ C P +I WR+ DG
Sbjct: 205 VLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADG 264
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLT 554
I R + G L I N D G YEC A N G++ A LT
Sbjct: 265 KPIARKARRHKS-NGILEIPNFQQEDAGLYECVAENSRGKNVARGQLT 311
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 152 bits (368), Expect = 9e-36
Identities = 117/398 (29%), Positives = 181/398 (45%), Gaps = 33/398 (8%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLM 238
+P+ E + P V + G C A G P P I+W R D + I R++ NG L
Sbjct: 224 EPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHK--SNGILE 281
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D GL+EC+A+N GK + R + + A P ++ + E
Sbjct: 282 IPNFQQEDAGLYECVAENSRGKN-------VARGQLTFY---AQPNWIQKINDIHVAMEE 331
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+V ++C A G PKP W NGE +L +RI ++ G++ I V SDAG+Y C EN
Sbjct: 332 -NVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ-GTLNITIVNLSDAGMYQCLAENK 389
Query: 359 HGKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILP 415
HG I ++ L V A P F + ++ G V CK K +PKP W + IL
Sbjct: 390 HGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILK 449
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ +S+D NL ++ VT+ D Y C A N G ++ L ++ P R+++ P
Sbjct: 450 ENERITISEDG-NLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKD----PTRVMVPP 504
Query: 476 EDMDAFKETSVQMPCEIESVPPASI--DWRKDGSRIVED------DRIS-ITVIGSLIIR 526
MD S+ +PC++ I W +G I D +R+ G L+IR
Sbjct: 505 SSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIR 564
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDA 564
N+ + G+Y C R +A+ L V+ P +A
Sbjct: 565 NIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEA 602
Score = 136 bits (329), Expect = 5e-31
Identities = 100/370 (27%), Positives = 167/370 (45%), Gaps = 8/370 (2%)
Query: 191 VEVSFGENAVFTCVATGEPAP-EILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL 249
V V G+ V C W+ + + R+ + G L + + ++D G
Sbjct: 132 VSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGN 191
Query: 250 FECMAKNVAG--KAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
+ C+ N K P +I+R + P + V P+ +V +C A
Sbjct: 192 YTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYE-PKIEVQFPET-VPTAKGATVKLECFA 249
Query: 308 TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVP 367
G P P + W + + + + NG + I N Q DAG+Y C EN GK A
Sbjct: 250 LGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQ 309
Query: 368 LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQ 427
L A P++I + + +NV++ CKA G PKP+ KW +N L + +
Sbjct: 310 LTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTL 369
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
N+T++ ++ D +Y C AEN G+I ++A L++ V R +LK + V
Sbjct: 370 NITIVNLS--DAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTL-VKVGGEVV 426
Query: 488 MPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
+ C+ ++ P W+K + E++RI+I+ G+L I NV+ +D G Y C A N +G
Sbjct: 427 IECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTA 486
Query: 548 TASVFLTVKD 557
+++ L VKD
Sbjct: 487 SSTGNLVVKD 496
Score = 104 bits (249), Expect = 2e-21
Identities = 107/386 (27%), Positives = 151/386 (39%), Gaps = 42/386 (10%)
Query: 182 PQFESEPNDVEV---SFGENAVFTCVATGEPAPEILW-LRDSEVIPLNENRYEIFDNGTL 237
P F EP+ V S + C G P P I W L ++V + RY + + G+L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVE-GSL 84
Query: 238 MVHEANENDD-GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+++ N+ D G ++C A N G S+ AK+ V V Q
Sbjct: 85 LINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQ------ 138
Query: 297 NETSVMFDCTATGFPKPH-----VAWYFNGERMLL-NERIILQHNGSILIKNVQNSDAGV 350
++ C P PH AW FN N R + Q G++ I V+ SD G
Sbjct: 139 ---GMVLLCG----PPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGN 191
Query: 351 YTCQVENI---HGKISASVPLEVT--------APPSFIVVPTNQTAIIGDNVWFTCKAKG 399
YTC V N H + PL + P + P G V C A G
Sbjct: 192 YTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALG 251
Query: 400 TPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
P P+I W R PI N L + ++D +Y C AEN G A L
Sbjct: 252 NPVPTIIW-RRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQL 310
Query: 460 TLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV 519
T P + K D+ E +V C+ P + W K+G ++ DRI I
Sbjct: 311 TF----YAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQ 366
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYG 545
G+L I V+++D G Y+C A N +G
Sbjct: 367 -GTLNITIVNLSDAGMYQCLAENKHG 391
Score = 70.5 bits (165), Expect = 4e-11
Identities = 77/288 (26%), Positives = 114/288 (39%), Gaps = 18/288 (6%)
Query: 283 PVFVSTPQKRFAKIN--ETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQ-HNGSIL 339
P+F+ P ++ E V +C G PKPH+ W NG + GS+L
Sbjct: 26 PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLL 85
Query: 340 IKNV-QNSDAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTC 395
I N + DAG Y C N G I S L+ +F T T + G + C
Sbjct: 86 INNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNF-KTRTRSTVSVRRGQGMVLLC 144
Query: 396 -KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN---DGG 451
+ + S W N +S + NL + +V + D Y C N +
Sbjct: 145 GPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHK 204
Query: 452 MIEASAVLTLEQVEII---PPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK-DG 506
++ L L ++ P+I ++ PE + K +V++ C P +I WR+ DG
Sbjct: 205 VLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADG 264
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLT 554
I R + G L I N D G YEC A N G++ A LT
Sbjct: 265 KPIARKARRHKS-NGILEIPNFQQEDAGLYECVAENSRGKNVARGQLT 311
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 151 bits (366), Expect = 2e-35
Identities = 111/385 (28%), Positives = 180/385 (46%), Gaps = 35/385 (9%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEANENDD 247
VE+S GE+ FTC A GEP I W ++ R + G L ++ AN D
Sbjct: 30 VELSVGESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDA 88
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
G++ C A + G+ + + +K + V +PQ+ F + + V+ C
Sbjct: 89 GIYRCQATDAKGQTQEATVVLEIYQKLTFRE-------VVSPQE-FKQGEDAEVV--CRV 138
Query: 308 TGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVE-NIHGKISA 364
+ P P V+W ++ E + + + R + N ++ I N+ SD G+Y C+ G+I
Sbjct: 139 SSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDF 198
Query: 365 SVPLEVTAPPSFIVVPT---NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
+ + P I +P N TA G+ + F+C+A G+P+P+I W+RN ++ +
Sbjct: 199 RDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYI 258
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
L N LT+ + D Y CRA N G E A L QV + P I LK E +
Sbjct: 259 LKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFL---QVFVQPHIIQLKNE--TTY 313
Query: 482 KETSVQMPCEIESVPPASIDWRK--DGSRIVEDDRI---SITVIG-----SLIIRNVSVT 531
+ V + C+ E P I W++ DG E D+ I V G SL I++V ++
Sbjct: 314 ENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLS 373
Query: 532 DTGRYECSAFNDYGRDTASVFLTVK 556
D+GRY+C A + G S++L ++
Sbjct: 374 DSGRYDCEAASRIGGHQKSMYLDIE 398
Score = 147 bits (355), Expect = 4e-34
Identities = 110/405 (27%), Positives = 180/405 (44%), Gaps = 36/405 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F + E GE+A C + PAP + WL + EV +++NR+ + N L
Sbjct: 113 QKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQ 172
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ N++D+G++ C + A G+ + +IV PP +S PQK F
Sbjct: 173 ILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVN---------VPPA-ISMPQKSFNATA 222
Query: 298 ETS--VMFDCTATGFPKPHVAWYFNGERMLLNERIILQ-HNGSILIKNVQNSDAGVYTCQ 354
E + F C A+G P+P ++W+ NG+ + NE+ IL+ N + ++N+ NSD G Y C+
Sbjct: 223 ERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCR 282
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N G+ L+V P I + N+T V C A+G P P I W R
Sbjct: 283 ATNKAGEDEKQAFLQVFVQPHIIQLK-NETTYENGQVTLVCDAEGEPIPEITWKRAVDGF 341
Query: 415 PIT-------GNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
T G + + + +L + +V D Y C A + G + S L +E
Sbjct: 342 TFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYA- 400
Query: 466 IIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS--- 522
P+ + +++ + + C+++S PPASI WR+D + + ++ +
Sbjct: 401 ---PKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRK 457
Query: 523 --LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAY 565
L I S D GRY C+A N G L + D +P Y
Sbjct: 458 MILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALAD--VPSSPY 500
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 150 bits (363), Expect = 4e-35
Identities = 106/393 (26%), Positives = 171/393 (43%), Gaps = 26/393 (6%)
Query: 180 QQPQFESEPNDVEV-SFGENAVFTCVATGEPAPEILWLRD-SEVIPLNENRYEIFDN-GT 236
+ PQF +P+ V V G++ F C TG P + W D +E+ + ++ D T
Sbjct: 1524 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 1583
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ A + G + C A+N AG A + K +E PP F+ K +
Sbjct: 1584 FQISGARVENSGTYVCEARNDAGTASCS-----IELKVKE-----PPTFIRE-LKPVEVV 1632
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTC 353
+ V +C TG P V W N + +++ L S+ I SD G Y C
Sbjct: 1633 KYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 1692
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
V N G S S + + PPSFI N T ++ + F G+P SI W ++ I
Sbjct: 1693 IVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 1752
Query: 414 LPITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L N+ +S D L + V Y C+A+N+ G+ A L +++ P +I
Sbjct: 1753 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----PAQI 1808
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNV 528
V K + +D ++ + + C + P + W KDG +IV S++ + S I++V
Sbjct: 1809 VEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSV 1868
Query: 529 SVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
D+G+Y ND+G + +L V D +P
Sbjct: 1869 MKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIP 1901
Score = 150 bits (363), Expect = 4e-35
Identities = 113/396 (28%), Positives = 178/396 (44%), Gaps = 30/396 (7%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYE 230
+ H++P P F+ +P V+++ GE+ F C TG +I W +D+ E+ P +
Sbjct: 3870 LSEHEVP---PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 3926
Query: 231 IFDN-GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ +N TL V + + D G + C A N+AGK S A++ V+ PP F+
Sbjct: 3927 LVENTATLTVLKVGKGDAGQYTCYASNIAGK-DSCSAQLGVQE---------PPRFIKKL 3976
Query: 290 Q-KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQN--- 345
+ R K +E + ++C G P+ V WY + + + + + S+ + + N
Sbjct: 3977 EPSRIVKQDEFT-RYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSV 4035
Query: 346 SDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
D+G YTC+ N G S+S L+V PP F P + G +V C+ +GTP +
Sbjct: 4036 EDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHV 4095
Query: 406 KWYRNTVILPITGNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
WY++ L + +N ++ +L V D Y C+A ND G + L+
Sbjct: 4096 SWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK- 4154
Query: 464 VEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITV--- 519
PPR V K D+ VQ+ IE P S+ W KD IV E D I I+
Sbjct: 4155 ---APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN 4211
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
I +L V + G+Y C ND G L+V
Sbjct: 4212 IATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV 4247
Score = 144 bits (349), Expect = 2e-33
Identities = 106/405 (26%), Positives = 177/405 (43%), Gaps = 22/405 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDN-GTL 237
+ P F +P+ ++V G N FT + G P + W + SE++P + + D+ L
Sbjct: 4438 EPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAEL 4497
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + + + G + C+ N AGKA S + ++ AP FV ++
Sbjct: 4498 ELFDVDTSQSGEYTCIVSNEAGKA-SCTTHLYIK---------APAKFVKR-LNDYSIEK 4546
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQ 354
++ + T TG P V W NG + ++R I IL I + DAG Y C
Sbjct: 4547 GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCY 4606
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+EN GK S S + + PP F+ +GD+ C+ GTP+ + WY+ L
Sbjct: 4607 IENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKL 4666
Query: 415 PITGNLVLSDDNQNLTLL--EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
T + N TL+ +V +D Y C+AEN G + AS LT+++ + +PP
Sbjct: 4667 RPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFS 4725
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTD 532
+ D+ V C I P S+ W KDG + + + + + + N+ TD
Sbjct: 4726 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTD 4785
Query: 533 ---TGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAM 574
G+Y C+A N G ++S L + + P + +A A+
Sbjct: 4786 RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAV 4830
Score = 142 bits (344), Expect = 8e-33
Identities = 112/404 (27%), Positives = 183/404 (45%), Gaps = 30/404 (7%)
Query: 165 TGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
T +S A + + P + P F+ +P ++V GE+A F C TG I W +D++ I
Sbjct: 2920 TASSSARLTARE-PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRP 2978
Query: 225 NENRYEIFDNGT---LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
N Y I G L + + + D G + C A N GK A++ V+
Sbjct: 2979 GGN-YTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCS-AQLSVKE--------- 3027
Query: 282 PPVFVSTPQ-KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI 340
PP FV + + AK E S+ +C +G P+ V+W+ N + + + + S+ +
Sbjct: 3028 PPKFVKKLEASKVAKQGE-SIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 3086
Query: 341 KNVQNS---DAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKA 397
+ + D+G Y C+ N G S S L V APP F P+ A+ G +V C+
Sbjct: 3087 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEI 3146
Query: 398 KGTPKPSIKWYRNTVILPITGNLVLSDD--NQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
GTP + W ++ + + ++ + NL +L + D YHC+A N+ G
Sbjct: 3147 SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVGSDTC 3206
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV---ED 512
S + ++ PPR V K D +V++ +E P S+ W KD ++ E+
Sbjct: 3207 SCSVKFKE----PPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESEN 3262
Query: 513 DRIS-ITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
RIS I I +L + + +++G+Y C ND G S LTV
Sbjct: 3263 TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 3306
Score = 140 bits (340), Expect = 2e-32
Identities = 108/391 (27%), Positives = 173/391 (44%), Gaps = 26/391 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDN-GTL 237
+ P F +E +E + G++ C G P + W + D+++ P E R +N TL
Sbjct: 2742 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 2801
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ ++ N ND G + C A+N G A SK I R+ PP F + K +
Sbjct: 2802 VFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQL-------PPSF-ARQLKDIEQTV 2853
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQ 354
V C G V WY +G + +E + + + ++ I S +G Y+C
Sbjct: 2854 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCS 2913
Query: 355 VENIHGKISASVPLEVTAP---PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
N G S+S L P P F + P + I G++ F C G I W ++
Sbjct: 2914 ASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 2973
Query: 412 VILPITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPP 469
+ GN ++ + +L +L+V + D Y C+A ND G SA L++++ PP
Sbjct: 2974 KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE----PP 3029
Query: 470 RIVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LII 525
+ V K E K+ S+Q+ C+I P + W ++ S + E + +++ I S L I
Sbjct: 3030 KFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTI 3089
Query: 526 RNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
S D+G Y C A N G + S LTVK
Sbjct: 3090 NEASAEDSGDYICEAHNGVGDASCSTALTVK 3120
Score = 140 bits (340), Expect = 2e-32
Identities = 97/381 (25%), Positives = 164/381 (43%), Gaps = 26/381 (6%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI-FDNGT--LMVHEAN 243
+P ++V+ G+ C G P W +D + + ++N+Y+I F N L +
Sbjct: 4256 KPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELT-SDNKYKISFFNKVSGLKIINVA 4314
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
+D G++ +N GK + + R PP F + K ++ +SV+
Sbjct: 4315 PSDSGVYSFEVQNPVGKDSCTASLQVSDRTV-------PPSF-TRKLKETNGLSGSSVVM 4366
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+C G P V+W+ G + + + + ++ + ++ SD+G YTC N+ G
Sbjct: 4367 ECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG 4426
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG-- 418
S PL V PPSF+ P + G NV FT KGTP S+ W++ + L + G
Sbjct: 4427 SDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSEL-VPGDR 4485
Query: 419 -NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N+ L D L L +V Y C N+ G + L ++ P + V + D
Sbjct: 4486 CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK----APAKFVKRLND 4541
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTG 534
K + + PP S+ W+K+G + R +IT L I + +V D G
Sbjct: 4542 YSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAG 4601
Query: 535 RYECSAFNDYGRDTASVFLTV 555
+Y C N G+D+ S + +
Sbjct: 4602 QYNCYIENASGKDSCSAQILI 4622
Score = 138 bits (334), Expect = 1e-31
Identities = 104/395 (26%), Positives = 178/395 (45%), Gaps = 29/395 (7%)
Query: 180 QQPQF--ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD-SEVIPLNENRYEIFDN-G 235
+ P+F + EP+ + V E + C G P ++LW +D +E+ ++ R D+
Sbjct: 3968 EPPRFIKKLEPSRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA 4026
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L +H + D G + C A N AG A S + K +E PP+F P
Sbjct: 4027 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL-----KVKE-----PPIFRKKPHP-IET 4075
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHN--GSILIKNVQNSDAGVYT 352
+ V +C G P HV+WY + + ++ I+ N SI I NV +D G Y
Sbjct: 4076 LKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQ 4135
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
C+ N G + + + APP F+ ++ + ++G V +G S+ W+++
Sbjct: 4136 CKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKG 4195
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAI---YHCRAENDGGMIEASAVLTLEQVEIIPP 469
+ + + ++N+ L+ +R + A Y C+ +ND GM E A L++ + P
Sbjct: 4196 EIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE----PA 4251
Query: 470 RIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIR 526
IV KPE + + + C + P S W KDG + D++ I+ + L I
Sbjct: 4252 TIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKII 4311
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
NV+ +D+G Y N G+D+ + L V D +P
Sbjct: 4312 NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVP 4346
Score = 135 bits (326), Expect = 1e-30
Identities = 110/436 (25%), Positives = 181/436 (41%), Gaps = 25/436 (5%)
Query: 135 CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVS 194
C+ S+ F+ LE E + + Y A+ H + F D V
Sbjct: 3545 CNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVE 3604
Query: 195 FGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM-VHEANENDDGLFEC 252
G V TG P + W++D +I +E + + T++ + E+ D + C
Sbjct: 3605 TGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSC 3664
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+ +N AG+ + ++ PP F+ + A I E + + C G P+
Sbjct: 3665 LIENEAGQDICEALVSVLE----------PPYFIEPLEHVEAVIGEPATL-QCKVDGTPE 3713
Query: 313 PHVAWYFNGERMLLNERIILQHN---GSILIKNVQNSDAGVYTCQVENIHGKISASVPLE 369
++WY ++ +Q S++I V +SD G Y+C+ +N G +++S L
Sbjct: 3714 IRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLV 3773
Query: 370 VTA---PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDN 426
+ A PP F + +G V F C+ G+ + WY++ V+L NL S +
Sbjct: 3774 IKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH 3833
Query: 427 QNLTLLEVTRDDDAI--YHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKET 484
TL + D I Y+C A N G +SA L L + E +PP LKP +D
Sbjct: 3834 NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-VPPFFDLKPVSVDLALGE 3892
Query: 485 SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRNVSVTDTGRYECSAF 541
S C + P I W KD I +T++ +L + V D G+Y C A
Sbjct: 3893 SGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYAS 3952
Query: 542 NDYGRDTASVFLTVKD 557
N G+D+ S L V++
Sbjct: 3953 NIAGKDSCSAQLGVQE 3968
Score = 134 bits (325), Expect = 2e-30
Identities = 106/392 (27%), Positives = 170/392 (43%), Gaps = 22/392 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGT-L 237
+ P FE P+ VEV G + FT V G P ++ W + S E++P + D T L
Sbjct: 3497 EPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTEL 3556
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ E + G + C+ N AG A S + V+ P FV F+
Sbjct: 3557 ELFEVQPLESGDYSCLVTNDAGSA-SCTTHLFVKE---------PATFVKRLAD-FSVET 3605
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQ 354
+ ++ + T TG P V+W + + +ER I + +IL I D Y+C
Sbjct: 3606 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 3665
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+EN G+ + V PP FI + A+IG+ CK GTP+ I WY+ L
Sbjct: 3666 IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKL 3725
Query: 415 PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ N +L + +V D Y C+A+N G + +SAVL + + +PP
Sbjct: 3726 RSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI-KARKLPPFFA 3784
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTD 532
K +D+ V C I P + W KDG + +D + + + ++ + TD
Sbjct: 3785 RKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTD 3844
Query: 533 ---TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G+Y CSA N G ++S L + ++ +P
Sbjct: 3845 QSHIGQYNCSASNPLGTASSSAKLILSEHEVP 3876
Score = 134 bits (325), Expect = 2e-30
Identities = 113/397 (28%), Positives = 173/397 (43%), Gaps = 37/397 (9%)
Query: 181 QPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TL 237
+P + EP + VE GE A C G P I W ++ + F N +L
Sbjct: 3683 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3742
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
++++ + +D G + C A N G S +I RK PP F ++ ++
Sbjct: 3743 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKL-------PPFFA----RKLKDVH 3791
Query: 298 ET---SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQ----HNGSIL-IKNVQNSDAG 349
ET V F+C G V+WY +G +LL + LQ HN + L I S G
Sbjct: 3792 ETLGFPVAFECRINGSEPLQVSWYKDG--VLLKDDANLQTSFVHNVATLQILQTDQSHIG 3849
Query: 350 VYTCQVENIHGKISASVPL---EVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIK 406
Y C N G S+S L E PP F + P + +G++ F C GT I
Sbjct: 3850 QYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT 3909
Query: 407 WYRNTVILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
W ++ + GN + L ++ LT+L+V + D Y C A N G SA L +++
Sbjct: 3910 WAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE- 3968
Query: 465 EIIPPRIVLKPEDMDAFKETS-VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
PPR + K E K+ + C+I P + W KD + I E + ++ + S+
Sbjct: 3969 ---PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSV 4025
Query: 524 II---RNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ N+SV D+G Y C A N G ++S L VK+
Sbjct: 4026 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 4062
Score = 134 bits (324), Expect = 2e-30
Identities = 98/389 (25%), Positives = 174/389 (44%), Gaps = 24/389 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--- 236
+ P F EP +EV G+N FT V G P ++ W R + + + +R I+ T
Sbjct: 2556 EPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAREL-VKGDRCNIYFEDTVAE 2614
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L + + + G + C+ N AG+A S ++ V+ P F+ +
Sbjct: 2615 LELFNIDISQSGEYTCVVSNNAGQA-SCTTRLFVKE---------PAAFLKRLSDHSVEP 2664
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTC 353
+ S++ + T TG V W +G + +E+ I+ IL I N DAG Y+C
Sbjct: 2665 GK-SIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSC 2723
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
++EN G+ + PP F+ A +GD+V C+ GTP+ ++ WY+
Sbjct: 2724 EIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTK 2783
Query: 414 LPITGNLVLSDDNQNLTLL--EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L T N TL+ +V +D Y C+AEN G + V +++ + +PP
Sbjct: 2784 LRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ-LPPSF 2842
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVT 531
+ +D++ V + C + P + W +DG + + + + + + ++ + T
Sbjct: 2843 ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQT 2902
Query: 532 D---TGRYECSAFNDYGRDTASVFLTVKD 557
D +G+Y CSA N G ++S LT ++
Sbjct: 2903 DLSHSGQYSCSASNPLGTASSSARLTARE 2931
Score = 129 bits (312), Expect = 6e-29
Identities = 94/379 (24%), Positives = 159/379 (41%), Gaps = 22/379 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLMVHEANE 244
+P + V+ G CV TG P W +D + + + F N +L + A
Sbjct: 3315 KPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM 3374
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D GL+ KN GK++ + + R PP F+ K I SV+ +
Sbjct: 3375 SDKGLYSFEVKNSVGKSNCTVSVHVSDRIV-------PPSFIRK-LKDVNAILGASVVLE 3426
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV---QNSDAGVYTCQVENIHGK 361
C +G V W+ +G ++ + + ++ N+ + SD G+YTC N+ G
Sbjct: 3427 CRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGS 3486
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT--VILPITGN 419
S L V PPSF P + + G ++ FT +GTP +KW++ + ++ + N
Sbjct: 3487 DECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCN 3546
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ L D L L EV + Y C ND G + L +++ P V + D
Sbjct: 3547 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE----PATFVKRLADFS 3602
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNV---SVTDTGRY 536
+ + + PP S+ W KD I + +R SIT+ I + ++ D +Y
Sbjct: 3603 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQY 3662
Query: 537 ECSAFNDYGRDTASVFLTV 555
C N+ G+D ++V
Sbjct: 3663 SCLIENEAGQDICEALVSV 3681
Score = 127 bits (307), Expect = 2e-28
Identities = 105/382 (27%), Positives = 161/382 (42%), Gaps = 25/382 (6%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN--END 246
+D V G++ + TG + W +D I +E + T ++ N + D
Sbjct: 2658 SDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRD 2717
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C +N AG+ +V + PP FV+ + A + + SV C
Sbjct: 2718 AGQYSCEIENEAGR---DVCGALV-------STLEPPYFVTELEPLEAAVGD-SVSLQCQ 2766
Query: 307 ATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQN-SDAGVYTCQVENIHGKIS 363
G P+ V+WY ++ R +N + L+ N N +D+G YTC+ EN G S
Sbjct: 2767 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 2826
Query: 364 ASVPLEVTA---PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
+ + PPSF + +G V TC+ G+ + WYR+ V+L NL
Sbjct: 2827 SKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENL 2886
Query: 421 VLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
S D+ L +L+ Y C A N G +SA LT + + P +KP +
Sbjct: 2887 QTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK-SPFFDIKPVSI 2945
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGR 535
D S C + P I W KD I +IT +G+ L I V D+G+
Sbjct: 2946 DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQ 3005
Query: 536 YECSAFNDYGRDTASVFLTVKD 557
Y C A ND G+D S L+VK+
Sbjct: 3006 YTCQATNDVGKDMCSAQLSVKE 3027
Score = 126 bits (303), Expect = 7e-28
Identities = 98/392 (25%), Positives = 168/392 (42%), Gaps = 25/392 (6%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLM-VH 240
+F ND + G+ + TG P + W ++ V P + ++ +
Sbjct: 4534 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIP 4593
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ D G + C +N +GK S A++++ PP FV + + + S
Sbjct: 4594 SSTVEDAGQYNCYIENASGK-DSCSAQILILE---------PPYFVKQLEPVKVSVGD-S 4642
Query: 301 VMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKN-VQNSDAGVYTCQVEN 357
C G P+ V+WY ++ ++ ++N + L+ N V +D+G Y C+ EN
Sbjct: 4643 ASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 4702
Query: 358 IHGKISASVPLEVTA---PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
G++SAS L V PPSF + +G V F C G+ S+ WY++ L
Sbjct: 4703 SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPL 4762
Query: 415 PITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ N+ S D+ L + + R Y C A N G +SA L L + + PP
Sbjct: 4763 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN-PPFFD 4821
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVS 529
++ +DA S C + P + W KD I + I+ + + L + V
Sbjct: 4822 IRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVD 4881
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
D+G+Y C A N+ G+D+ + L +K+ L+P
Sbjct: 4882 KGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP 4913
Score = 124 bits (299), Expect = 2e-27
Identities = 99/402 (24%), Positives = 174/402 (43%), Gaps = 25/402 (6%)
Query: 176 DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF-DN 234
++P P + D S G+ A F C +G + +D ++ P R F D
Sbjct: 4 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT 63
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHS------KPAKMIVRRKAE---EHKSPAPPVF 285
L + EA D+G + +A N G+ S + + I+ + E E + A PV
Sbjct: 64 YQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVI 123
Query: 286 VSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN---GSILIKN 342
+ + + F C P W+ G + +++ ++ + S+ I
Sbjct: 124 KRKIEPLEVALGHLA-KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 182
Query: 343 VQNSDAGVYTCQVENIHGKISASVPLEVTA--PPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
Q D G YTC+ N +G +S + L VT PP+F+ P + T +G F C GT
Sbjct: 183 TQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGT 242
Query: 401 PKPSIKWYRNTVILPITGNLVLSD-DNQN-LTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
P W ++ L + N +SD +N++ L L +T D +Y C+A N G + +
Sbjct: 243 PVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFG----ADI 298
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV--EDDRIS 516
E + I P + + E + + V + C+++ ++ W KDG ++ +D +I
Sbjct: 299 CQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKIC 358
Query: 517 I-TVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I +L I + D+G Y C+A N+ G + S +TV++
Sbjct: 359 FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 400
Score = 123 bits (297), Expect = 4e-27
Identities = 99/391 (25%), Positives = 168/391 (42%), Gaps = 26/391 (6%)
Query: 180 QQP-QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--T 236
Q+P Q + V+V+ + CV G P ++ WL+D + I + F+N +
Sbjct: 1803 QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 1862
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ + D G + +N G + ++ + PP F K K+
Sbjct: 1863 FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNI-------PPSFTKKLTK-MDKV 1914
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIIL---QHNGSILIKNVQNSDAGVYTC 353
+S+ +C +G W+ +G+ + + + L + + S+ + N++ D YTC
Sbjct: 1915 LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTC 1974
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
+V N+ G + S L V PPSF+V P Q AI V F KGTP IKW+++ V
Sbjct: 1975 KVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVE 2034
Query: 414 LPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
L ++G + L L L V Y C ND G + +L + + PP+
Sbjct: 2035 L-VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE----PPK 2089
Query: 471 IVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLII---R 526
V K E K S ++ C+I P + W ++ + D+ +T I S+ +
Sbjct: 2090 FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 2149
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
N+S D+G + C A N G + S + VK+
Sbjct: 2150 NLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 2180
Score = 122 bits (293), Expect = 1e-26
Identities = 96/376 (25%), Positives = 160/376 (42%), Gaps = 26/376 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM-V 239
P F S P + G+ A F C TG P E +W +D + + N R +N ++ +
Sbjct: 216 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 275
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
D G++ C A N G A A++I+ K P F+ + + IN+
Sbjct: 276 SNLTIQDRGVYSCKASNKFG-ADICQAELIIIDK---------PHFIKELEPVQSAINK- 324
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHN-GSILIKNVQNSDAGVYTCQVE 356
V +C K V W +G+++ + +I + ++ I + D+G Y C
Sbjct: 325 KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTAS 384
Query: 357 NIHGKISASVPLEVTAPPSFI-VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
N G S S + V PPSF+ V + + G++ CK KG+P + W++N L
Sbjct: 385 NEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELS 444
Query: 416 ITGNLVLSDDNQN--LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ + + N L + +V +D Y C A ND G S + +++ PP +
Sbjct: 445 ESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE----PPSFIK 500
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI---IRNVSV 530
E D + T+ + CE+ P I W KD +I + + SL+ I + +
Sbjct: 501 TLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNS 560
Query: 531 TDTGRYECSAFNDYGR 546
D G YEC N+ G+
Sbjct: 561 ADVGEYECVVANEVGK 576
Score = 122 bits (293), Expect = 1e-26
Identities = 95/389 (24%), Positives = 161/389 (41%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+ P F +P+ +E G + C G P + W +D + + + +N +
Sbjct: 4062 EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSI 4121
Query: 240 HEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
H N + D G ++C A N G S + KA PP FV +
Sbjct: 4122 HILNVDAADIGEYQCKATNDVG---SDTCVGSIALKA-------PPRFVKKLSDISTVVG 4171
Query: 298 ETSVMFDCTATGFPKPHVAWYFN-GERMLLNERIILQHNGSIL---IKNVQNSDAGVYTC 353
+ V T G V W+ + GE + ++ I + ++ +I V+ ++AG YTC
Sbjct: 4172 K-EVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 4230
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
Q++N G L V P + + P + GD C GTP+ S KW+++
Sbjct: 4231 QIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKE 4290
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L +S N+ L ++ V D +Y +N G +A L + +PP
Sbjct: 4291 LTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSD-RTVPPSF 4349
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNV 528
K ++ + +SV M C++ PP S+ W +G+ I + T+ +L + +
Sbjct: 4350 TRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNML 4409
Query: 529 SVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+D+G Y C A N G D S LTV++
Sbjct: 4410 EESDSGDYTCIATNMAGSDECSAPLTVRE 4438
Score = 121 bits (291), Expect = 2e-26
Identities = 91/379 (24%), Positives = 163/379 (43%), Gaps = 23/379 (6%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--LMVHEANENDDG 248
++V+ G+ A G P + W +D + ++ F N L + A +D G
Sbjct: 691 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 750
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
+ N G + + ++ R AP F + P + + + DC
Sbjct: 751 QYTFEISNEVGSSSCETTFTVLDRDI------AP--FFTKPLRNVDSVVNGTCRLDCKIA 802
Query: 309 GFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
G V+W+ +G+ + ++R ++ S+ I V +DAG +TC+ N G +S
Sbjct: 803 GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 862
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
L V PPSF+ P ++ + G V +G+ +I+W++ L G+ ++ +
Sbjct: 863 GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 922
Query: 426 --NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
+L L V D Y C+ N G +E SA L +++ P V K E K+
Sbjct: 923 ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE----PATFVEKLEPSQLLKK 978
Query: 484 -TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECS 539
+ Q+ C++ PP I W + I E + ++ + S L + +V + D+G Y C
Sbjct: 979 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 1038
Query: 540 AFNDYGRDTASVFLTVKDN 558
A N+ G D S + VK++
Sbjct: 1039 AQNEAGSDHCSSIVIVKES 1057
Score = 119 bits (287), Expect = 6e-26
Identities = 99/388 (25%), Positives = 163/388 (42%), Gaps = 26/388 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLM 238
+P F E V+ + + C + + W +D + +P ++ F++ TL
Sbjct: 308 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 367
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ A D G + C A N AG + S A + VR PP FV + +
Sbjct: 368 IPLAKLKDSGTYVCTASNEAGSS-SCSATVTVRE---------PPSFVKKVDPSYLMLPG 417
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
S C G P V W+ N + + + R+ ++ +IL I +V+ D+G Y+C+
Sbjct: 418 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEA 477
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
N G S S + + PPSFI + G N C+ GT I W+++ +
Sbjct: 478 VNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIR 537
Query: 416 ITGNLVLSDDNQNLTLLEV---TRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ L ++L LE+ D Y C N+ G A L++ PP V
Sbjct: 538 SSKKYRLF-SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE----PPTFV 592
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNVS 529
K +D+ A +V + + P S+ W K I ED +I ++ + LII +V
Sbjct: 593 KKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQ 652
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKD 557
++ G+Y C A N+ G T+ L VK+
Sbjct: 653 ISFGGKYTCLAENEAGSQTSVGELIVKE 680
Score = 119 bits (287), Expect = 6e-26
Identities = 90/387 (23%), Positives = 161/387 (41%), Gaps = 26/387 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDN-GTLMV 239
P F + ++ G C+ G I W +D + I +E ++ DN L +
Sbjct: 1340 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 1399
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C A N AG H++ + + ++ PP FV PQ + N T
Sbjct: 1400 SQLEGTDSGTYTCSATNKAG--HNQCSGHLTVKE--------PPYFVEKPQSQDVNPN-T 1448
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIK--NVQNSDAGVYTCQVE 356
V G + W+ + + + R + + + S ++ + +D+G Y CQ+
Sbjct: 1449 RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 1508
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWY--RNTVI 413
N G ++ L V PP FI P+ + G + F C+ GTPK + WY N +
Sbjct: 1509 NDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEIT 1568
Query: 414 LPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ D + ++ Y C A ND G S L +++ PP +
Sbjct: 1569 AIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE----PPTFIR 1624
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT---VIGSLIIRNVSV 530
+ + ++ K + V++ CE+ PP + W K+ I + ++T + +L I
Sbjct: 1625 ELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDP 1684
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKD 557
+DTG Y+C N+ G + S + +K+
Sbjct: 1685 SDTGEYQCIVSNEGGSCSCSTRVALKE 1711
Score = 119 bits (287), Expect = 6e-26
Identities = 102/389 (26%), Positives = 166/389 (42%), Gaps = 27/389 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI----FDNGTL 237
P F +P+ V G + + C +G P E++W++D + + N +++I FD L
Sbjct: 3123 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVR-NSKKFKITSKHFDTN-L 3180
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A N G S V+ K PP FV I
Sbjct: 3181 HILNLEASDVGEYHCKATNEVG---SDTCSCSVKFKE-------PPRFVKKLSDTSTLIG 3230
Query: 298 ETSVMFDCTATGFPKPHVAWYFN-GE--RMLLNERIILQHN-GSILIKNVQNSDAGVYTC 353
+ +V GF V W + GE R N RI N ++ + + + S++G Y C
Sbjct: 3231 D-AVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 3289
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
Q++N G S L V P I P T G+ C GTP+ S KW+++
Sbjct: 3290 QIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRE 3349
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L ++ N+ +L + D +Y +N G + + + I+PP
Sbjct: 3350 LSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD-RIVPPSF 3408
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSV- 530
+ K +D++A SV + C + P S+ W +DG+ IV + + ++ N+S+
Sbjct: 3409 IRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLL 3468
Query: 531 --TDTGRYECSAFNDYGRDTASVFLTVKD 557
+DTG Y C A N G D S LTV++
Sbjct: 3469 EPSDTGIYTCVAANVAGSDECSAVLTVQE 3497
Score = 115 bits (276), Expect = 1e-24
Identities = 92/411 (22%), Positives = 172/411 (41%), Gaps = 33/411 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TLMV 239
P F + G + + C G + W + I F + TL +
Sbjct: 2465 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 2524
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ + +D G + C+A NVAG + A + V+ PP FV P+ +
Sbjct: 2525 NSLDSSDMGNYTCVAANVAGSDECR-AVLTVQE---------PPSFVKEPEP-LEVLPGK 2573
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTCQVE 356
+V F G P V W+ ++ +R + ++ + N+ S +G YTC V
Sbjct: 2574 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 2633
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ S + L V P +F+ ++ + G ++ GT S+ W ++ +
Sbjct: 2634 NNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 2693
Query: 417 TG--NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-TLEQVEIIPPRIVL 473
+ N+V ++ L +L T+ D Y C EN+ G A++ TLE PP V
Sbjct: 2694 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE-----PPYFVT 2748
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI--VEDDRISITV-IGSLIIRNVSV 530
+ E ++A SV + C++ P ++ W K +++ + R T + +L+ V++
Sbjct: 2749 ELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNI 2808
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAMRDVDQAI 581
D+G Y C A N G ++ +++ LP + + ++D++Q +
Sbjct: 2809 NDSGEYTCKAENSIGTASSKTVFRIQERQLPP------SFARQLKDIEQTV 2853
Score = 114 bits (274), Expect = 2e-24
Identities = 86/372 (23%), Positives = 145/372 (38%), Gaps = 22/372 (5%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLMVHEANENDDGLF 250
V+ GE C G P + W +D +++ ++ F N +L + D G +
Sbjct: 2380 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTY 2439
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+N GK+ S A + V +A PP F K + S + +C G
Sbjct: 2440 TFQVQNNVGKS-SCTAVVDVSDRA------VPPSFTRR-LKNTGGVLGASCILECKVAGS 2491
Query: 311 PKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTCQVENIHGKISASVP 367
VAW+ +++ + + ++ + ++ +SD G YTC N+ G
Sbjct: 2492 SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 2551
Query: 368 LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT--VILPITGNLVLSDD 425
L V PPSF+ P + G NV FT +GTP + W+R ++ N+ D
Sbjct: 2552 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 2611
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
L L + Y C N+ G + L +++ P + + D S
Sbjct: 2612 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE----PAAFLKRLSDHSVEPGKS 2667
Query: 486 VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECSAFN 542
+ + P S+ W+KDG I ++ +I L I N + D G+Y C N
Sbjct: 2668 IILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN 2727
Query: 543 DYGRDTASVFLT 554
+ GRD ++
Sbjct: 2728 EAGRDVCGALVS 2739
Score = 112 bits (270), Expect = 7e-24
Identities = 96/403 (23%), Positives = 160/403 (39%), Gaps = 24/403 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFD--NGTL 237
+ P F ++P +V G G I W + ++ + + Y + +L
Sbjct: 869 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 928
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
++ +D G + C NVAG A + V K PA V P + K +
Sbjct: 929 ELYLVKTSDSGTYTCKVSNVAGGVECS-ANLFV-------KEPATFVEKLEPSQLLKKGD 980
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQ 354
T + C TG P + W+ N + + + ++ + + +V D+G Y C+
Sbjct: 981 ATQLA--CKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 1038
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+N G S + V P F + +V + GTP I W+++ IL
Sbjct: 1039 AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 1098
Query: 415 PITGNL--VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ D +L +L+ D Y CR N+ G SA +TL + PP +
Sbjct: 1099 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE----PPSFI 1154
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNVS 529
K E + + + ++ P ++ W KD I EDD I +T + SL + +
Sbjct: 1155 KKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIE 1214
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQ 572
V G+Y C A ND G S L+VK+ + V+I +TQ
Sbjct: 1215 VKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQ 1257
Score = 109 bits (262), Expect = 7e-23
Identities = 96/390 (24%), Positives = 160/390 (41%), Gaps = 25/390 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFD-NGTLM 238
+ P F S P VE C +G P E++W +D + + +Y+I N
Sbjct: 2180 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLR-SSKKYKIASKNFHTS 2238
Query: 239 VHEAN--ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+H N +D G + C A+N G S V+ K PP FVS
Sbjct: 2239 IHILNVDTSDIGEYHCKAQNEVG---SDTCVCTVKLKE-------PPRFVSKLNSLTVVA 2288
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
E + + + G V W E ++ N RI N + L + ++AG Y
Sbjct: 2289 GEPAEL-QASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 2347
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
CQ++N G L V P + T +G+ CK GTP+ S++WY++
Sbjct: 2348 CQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGK 2407
Query: 413 ILPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
+L + S N+ +L +L V R D Y + +N+ G +AV+ + +PP
Sbjct: 2408 LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPS 2466
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRN 527
+ ++ S + C++ P S+ W + ++IV + T + +L + +
Sbjct: 2467 FTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNS 2526
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +D G Y C A N G D LTV++
Sbjct: 2527 LDSSDMGNYTCVAANVAGSDECRAVLTVQE 2556
Score = 109 bits (261), Expect = 9e-23
Identities = 94/383 (24%), Positives = 157/383 (40%), Gaps = 25/383 (6%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEAN 243
E ++V+ G+ A +G W +D + + L ++Y+I T L +
Sbjct: 1249 EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLG-SKYKISVTDTVSILKIISTE 1307
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
+ D G + +N G++ K A++ V PP F K+ I + +
Sbjct: 1308 KKDSGEYTFEVQNDVGRSSCK-ARINVLDLI------IPPSFTKK-LKKMDSIKGSFIDL 1359
Query: 304 DCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G + W+ + + + +E+ N + L I ++ +D+G YTC N G
Sbjct: 1360 ECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 1419
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NTVILPITGN 419
S L V PP F+ P +Q V GT +IKW++ N +
Sbjct: 1420 HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 1479
Query: 420 LVLSDD-NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
V DD + +L L D Y C+ ND G + A L +++ PP+ + KP +
Sbjct: 1480 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE----PPQFIKKPSPV 1535
Query: 479 DAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVS---VTDTG 534
+ S C+I P + W DG+ I + I+ I L +S V ++G
Sbjct: 1536 LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 1595
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A ND G + S+ L VK+
Sbjct: 1596 TYVCEARNDAGTASCSIELKVKE 1618
Score = 106 bits (255), Expect = 5e-22
Identities = 111/441 (25%), Positives = 186/441 (42%), Gaps = 39/441 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI--FDNGT-LM 238
P F+ V+ GE+A F C TG ++ W +DS I + +Y+I +N L
Sbjct: 4818 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR-SGGKYQISYLENSAHLT 4876
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
V + ++ D G + C A N GK S A++ ++ + PP F + +
Sbjct: 4877 VLKVDKGDSGQYTCYAVNEVGK-DSCTAQLNIKERL------IPPSFTKRLSETVEETEG 4929
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSIL-IKNVQNSDAGVYTCQV 355
S + G VAWY N + N I ++N +L ++ +DAG+YTC+V
Sbjct: 4930 NSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKV 4989
Query: 356 ENIHGKI---SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NT 411
N G S+ V E PP F T T G+ V +C +G+ I+W +
Sbjct: 4990 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 5049
Query: 412 VILPITG-NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
I P + + L L +V + D Y C+A N G + +T++ + P
Sbjct: 5050 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 5109
Query: 471 -----------IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISIT 518
V +P+ + ++T+ ++ P ++ W K R + + R+ I
Sbjct: 5110 TKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIH 5169
Query: 519 VIGS---LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV----KDNLLPGDAYVNIALT 571
G L IR+ + TD+G Y C AFN++G ++V L V K + GD + T
Sbjct: 5170 QKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKT 5229
Query: 572 QAM-RDVDQAIERTVDQLFKN 591
+ + + E + +L KN
Sbjct: 5230 PILKKGAGEEEEIDIMELLKN 5250
Score = 106 bits (254), Expect = 6e-22
Identities = 90/386 (23%), Positives = 164/386 (42%), Gaps = 28/386 (7%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDN-GTLMVHEANE 244
EP+ + + G+ C TG P +I W D E+ +++R ++ L + +
Sbjct: 971 EPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGI 1029
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G + C A+N AG H + +++ +++ P+ V + E VM
Sbjct: 1030 EDSGEYMCEAQNEAGSDHC--SSIVIVKESPYFTKEFKPIEV---------LKEYDVMLL 1078
Query: 305 CTATGFPKPHVAWYFNGERMLLNER----IILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
G P + W F +L + R I H S+ I +DAG Y C+V N G
Sbjct: 1079 AEVAGTPPFEITW-FKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 1137
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
S + + PPSFI + +++ G F KG+ ++ W +++ + N+
Sbjct: 1138 SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNI 1197
Query: 421 VLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
++ +N +L L + D Y C+A+ND G+ SA+L++++ P I + +
Sbjct: 1198 RMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE----PATITEEAVSI 1253
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVT---DTGR 535
D + + + + W KDG + + I+V ++ I + T D+G
Sbjct: 1254 DVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 1313
Query: 536 YECSAFNDYGRDTASVFLTVKDNLLP 561
Y ND GR + + V D ++P
Sbjct: 1314 YTFEVQNDVGRSSCKARINVLDLIIP 1339
Score = 105 bits (251), Expect = 1e-21
Identities = 85/378 (22%), Positives = 152/378 (40%), Gaps = 27/378 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--L 237
+ P F +P + F + G P +I W +D + + + T L
Sbjct: 1993 EPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFL 2052
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ-KRFAKI 296
++ + + G + C N G + S ++V PP FV + + K
Sbjct: 2053 NLYSVDASKTGQYTCHVTNDVG-SDSCTTMLLVTE---------PPKFVKKLEASKIVKA 2102
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI---KNVQNSDAGVYTC 353
++S + +C G P+ V W+ N + +++ + S+ + N+ D+G + C
Sbjct: 2103 GDSSRL-ECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFIC 2161
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
+ +N G S S + V PP F P + V C+ GTP + WY++
Sbjct: 2162 EAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQ 2221
Query: 414 LPITGNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L + ++ N ++ +L V D YHC+A+N+ G + V T++ E PPR
Sbjct: 2222 LRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG--SDTCVCTVKLKE--PPRF 2277
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITV---IGSLIIRN 527
V K + ++ IE P + W K+ ++ E + I IT + +L
Sbjct: 2278 VSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAK 2337
Query: 528 VSVTDTGRYECSAFNDYG 545
+ G+Y C ND G
Sbjct: 2338 AEPANAGKYICQIKNDGG 2355
Score = 103 bits (247), Expect = 4e-21
Identities = 106/439 (24%), Positives = 159/439 (36%), Gaps = 30/439 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM- 238
+ P F ++ G NA+ C +G EI W +D + I + +Y +F +L+
Sbjct: 494 EPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI-RSSKKYRLFSQKSLVC 552
Query: 239 --VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N D G +EC+ N GK H PP FV A
Sbjct: 553 LEIFSFNSADVGEYECVVANEVGKCGCMAT----------HLLKEPPTFVKKVDDLIALG 602
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI---LIKNVQNSDAGVYTC 353
+T V G V W E + + +I + + + +I +VQ S G YTC
Sbjct: 603 GQT-VTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTC 661
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
EN G ++ L V P I GD GTP+ KWY++
Sbjct: 662 LAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 721
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L + +S N L D Y N+ G T+ +I P
Sbjct: 722 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP--F 779
Query: 472 VLKP-EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRN 527
KP ++D+ + ++ C+I P + W KDG I DR I + SL I
Sbjct: 780 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIR 839
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDN----LLPGDAYVNIALTQAMRDVDQAIER 583
V + D G + C A N G +S L V++ PG V ++ Q
Sbjct: 840 VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTP 899
Query: 584 TVDQLFKNRSAVVNIGDLY 602
+ FK +V+ G Y
Sbjct: 900 LTIRWFKGNKELVSGGSCY 918
Score = 72.9 bits (171), Expect = 7e-12
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 16/206 (7%)
Query: 178 PCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT- 236
P + P F+ V VS GE +C G I WL+ I ++ F +GT
Sbjct: 5007 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTA 5066
Query: 237 -LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRK---AEEHKSPAPP---VFVSTP 289
L + + + D G + C A NVAG +K +K+ ++ K A K A FVS P
Sbjct: 5067 VLELRDVAKADSGDYVCKASNVAGSDTTK-SKVTIKDKPAVAPATKKAAVDGRLFFVSEP 5125
Query: 290 QKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNG---SILIKNVQ 344
Q + +T+ F G P P+V W G+ LN+ R+ + G + I++
Sbjct: 5126 QS-IRVVEKTTATFIAKVGGDPIPNVKW-TKGKWRQLNQGGRVFIHQKGDEAKLEIRDTT 5183
Query: 345 NSDAGVYTCQVENIHGKISASVPLEV 370
+D+G+Y C N HG+I ++V L+V
Sbjct: 5184 KTDSGLYRCVAFNEHGEIESNVNLQV 5209
Score = 72.1 bits (169), Expect = 1e-11
Identities = 62/214 (28%), Positives = 86/214 (40%), Gaps = 22/214 (10%)
Query: 369 EVTAPPSFIVVPTNQTAII-GDNVWFTCKAKGTPKPSIKWY-RNTVILPITG-NLVLSDD 425
E+ P I+ P T G F C+ GT + WY ++ I P + +D
Sbjct: 4 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED 62
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII---------------PPR 470
L + E +D+ Y A N G + ++A L+LE E I P
Sbjct: 63 TYQLEIAEAYPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPV 122
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT---VIGSLIIRN 527
I K E ++ + CEI+S P W K G I E D+ SI I SL I
Sbjct: 123 IKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILR 182
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
V D G Y C A N+YG + + LTV + P
Sbjct: 183 TQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 216
Score = 46.8 bits (106), Expect = 5e-04
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 24/208 (11%)
Query: 305 CTAT-GFPKPHVA--WYFNGERMLLNER--IILQHN-GSILIKNVQNSDAGVYTCQVENI 358
CT T F P+V W+ NG + R ++H + I +V+ D G YTC+ E++
Sbjct: 5427 CTMTVQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL 5486
Query: 359 HGKISASV---PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
+ P++ T IVV +Q+A F C+ + WY+ L
Sbjct: 5487 ETSAELRIEAEPIQFTKRIQNIVVSEHQSAT------FECEV-SFDDAIVTWYKGPTELT 5539
Query: 416 ITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAE-NDGGMIEASAVLTLEQVEIIPPRIV 472
+ +D + +T+ VT DD+ +Y A G ++A L L EI ++
Sbjct: 5540 ESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEI---KLE 5596
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASI 500
LKP D+ + MP I +VPP I
Sbjct: 5597 LKPPDIPDSRVPIPTMP--IRAVPPEEI 5622
Score = 33.1 bits (72), Expect = 6.9
Identities = 41/173 (23%), Positives = 79/173 (45%), Gaps = 16/173 (9%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIK-WYRN-TVILPITGNLVL 422
+VPL+ I++ ++ +G + F C +P +I W ++ + I + +
Sbjct: 7799 AVPLKFVKEIKDIIL--TESEFVGSSAIFECLV--SPSTAITTWMKDGSNIRESPKHRFI 7854
Query: 423 SDD-NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK-PEDMDA 480
+D ++ L +++V D Y C ++A L +E+ +P R V E++
Sbjct: 7855 ADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE---LPVRFVKTLEEEVTV 7911
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVTD 532
K + + CE+ + WRKDG +VE RI VIG ++R +++ D
Sbjct: 7912 VKGQPLYLSCELNK--ERDVVWRKDGKIVVEKPGRIVPGVIG--LMRALTIND 7960
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 150 bits (363), Expect = 4e-35
Identities = 106/393 (26%), Positives = 171/393 (43%), Gaps = 26/393 (6%)
Query: 180 QQPQFESEPNDVEV-SFGENAVFTCVATGEPAPEILWLRD-SEVIPLNENRYEIFDN-GT 236
+ PQF +P+ V V G++ F C TG P + W D +E+ + ++ D T
Sbjct: 5786 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 5845
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ A + G + C A+N AG A + K +E PP F+ K +
Sbjct: 5846 FQISGARVENSGTYVCEARNDAGTASCS-----IELKVKE-----PPTFIRE-LKPVEVV 5894
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTC 353
+ V +C TG P V W N + +++ L S+ I SD G Y C
Sbjct: 5895 KYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQC 5954
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
V N G S S + + PPSFI N T ++ + F G+P SI W ++ I
Sbjct: 5955 IVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQI 6014
Query: 414 LPITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L N+ +S D L + V Y C+A+N+ G+ A L +++ P +I
Sbjct: 6015 LDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----PAQI 6070
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNV 528
V K + +D ++ + + C + P + W KDG +IV S++ + S I++V
Sbjct: 6071 VEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSV 6130
Query: 529 SVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
D+G+Y ND+G + +L V D +P
Sbjct: 6131 MKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIP 6163
Score = 149 bits (361), Expect = 7e-35
Identities = 113/396 (28%), Positives = 177/396 (44%), Gaps = 30/396 (7%)
Query: 172 MKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYE 230
+ H++P P F+ +P V+++ GE+ F C TG +I W +D+ E+ P +
Sbjct: 8132 LSEHEVP---PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMT 8188
Query: 231 IFDN-GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
+ +N TL V + + D G + C A N+AGK S A + V+ PP F+
Sbjct: 8189 LVENTATLTVLKVGKGDAGQYTCYASNIAGK-DSCSAHLGVQE---------PPRFIKKL 8238
Query: 290 Q-KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQN--- 345
+ R K +E + ++C G P+ V WY + + + + + S+ + + N
Sbjct: 8239 EPSRIVKQDEFT-RYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSV 8297
Query: 346 SDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSI 405
D+G YTC+ N G S+S L+V PP F P + G +V C+ +GTP +
Sbjct: 8298 EDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHV 8357
Query: 406 KWYRNTVILPITGNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
WY++ L + +N ++ +L V D Y C+A ND G + L+
Sbjct: 8358 SWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALK- 8416
Query: 464 VEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITV--- 519
PPR V K D+ VQ+ IE P S+ W KD IV E D I I+
Sbjct: 8417 ---APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN 8473
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
I +L V + G+Y C ND G L+V
Sbjct: 8474 IATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSV 8509
Score = 145 bits (351), Expect = 1e-33
Identities = 106/405 (26%), Positives = 178/405 (43%), Gaps = 22/405 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDN-GTL 237
+ P F +P+ ++V G N FT + G P + W + SE++P + + D+ L
Sbjct: 8700 EPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAEL 8759
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + + + G + C+ N AGKA S + ++ AP FV ++
Sbjct: 8760 ELFDVDTSQSGEYTCIVSNEAGKA-SCTTHLYIK---------APAKFVKR-LNDYSIEK 8808
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQ 354
++ + T TG P V W NG + ++R I +IL I + DAG Y C
Sbjct: 8809 GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY 8868
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+EN GK S S + + PP F+ +GD+ C+ GTP+ + WY+ L
Sbjct: 8869 IENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKL 8928
Query: 415 PITGNLVLSDDNQNLTLL--EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
T + N TL+ +V +D Y C+AEN G + AS LT+++ + +PP
Sbjct: 8929 RPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFS 8987
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTD 532
+ D+ V C I P S+ W KDG + + + + + + N+ TD
Sbjct: 8988 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTD 9047
Query: 533 ---TGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAM 574
G+Y C+A N G ++S L + + P + +A A+
Sbjct: 9048 RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAV 9092
Score = 140 bits (340), Expect = 2e-32
Identities = 108/391 (27%), Positives = 173/391 (44%), Gaps = 26/391 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDN-GTL 237
+ P F +E +E + G++ C G P + W + D+++ P E R +N TL
Sbjct: 7004 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 7063
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ ++ N ND G + C A+N G A SK I R+ PP F + K +
Sbjct: 7064 VFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQL-------PPSF-ARQLKDIEQTV 7115
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQ 354
V C G V WY +G + +E + + + ++ I S +G Y+C
Sbjct: 7116 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCS 7175
Query: 355 VENIHGKISASVPLEVTAP---PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
N G S+S L P P F + P + I G++ F C G I W ++
Sbjct: 7176 ASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDN 7235
Query: 412 VILPITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPP 469
+ GN ++ + +L +L+V + D Y C+A ND G SA L++++ PP
Sbjct: 7236 KEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE----PP 7291
Query: 470 RIVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LII 525
+ V K E K+ S+Q+ C+I P + W ++ S + E + +++ I S L I
Sbjct: 7292 KFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTI 7351
Query: 526 RNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
S D+G Y C A N G + S LTVK
Sbjct: 7352 NEASAEDSGDYICEAHNGVGDASCSTALTVK 7382
Score = 140 bits (340), Expect = 2e-32
Identities = 97/381 (25%), Positives = 164/381 (43%), Gaps = 26/381 (6%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI-FDNGT--LMVHEAN 243
+P ++V+ G+ C G P W +D + + ++N+Y+I F N L +
Sbjct: 8518 KPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELT-SDNKYKISFFNKVSGLKIINVA 8576
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
+D G++ +N GK + + R PP F + K ++ +SV+
Sbjct: 8577 PSDSGVYSFEVQNPVGKDSCTASLQVSDRTV-------PPSF-TRKLKETNGLSGSSVVM 8628
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+C G P V+W+ G + + + + ++ + ++ SD+G YTC N+ G
Sbjct: 8629 ECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAG 8688
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG-- 418
S PL V PPSF+ P + G NV FT KGTP S+ W++ + L + G
Sbjct: 8689 SDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSEL-VPGDR 8747
Query: 419 -NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N+ L D L L +V Y C N+ G + L ++ P + V + D
Sbjct: 8748 CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK----APAKFVKRLND 8803
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRNVSVTDTG 534
K + + PP S+ W+K+G + R +IT L I + +V D G
Sbjct: 8804 YSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAG 8863
Query: 535 RYECSAFNDYGRDTASVFLTV 555
+Y C N G+D+ S + +
Sbjct: 8864 QYNCYIENASGKDSCSAQILI 8884
Score = 140 bits (339), Expect = 3e-32
Identities = 111/404 (27%), Positives = 183/404 (45%), Gaps = 30/404 (7%)
Query: 165 TGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
T +S A + + P + P F+ +P ++V GE+A F C TG I W +D++ I
Sbjct: 7182 TASSSARLTARE-PKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRP 7240
Query: 225 NENRYEIFDNGT---LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
N Y I G L + + + D G + C A N GK A++ V+
Sbjct: 7241 GGN-YTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCS-AQLSVKE--------- 7289
Query: 282 PPVFVSTPQ-KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI 340
PP FV + + AK E S+ +C +G P+ V+W+ N + + + + S+ +
Sbjct: 7290 PPKFVKKLEASKVAKQGE-SIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348
Query: 341 KNVQNS---DAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKA 397
+ + D+G Y C+ N G S S L V APP F P+ A+ G +V C+
Sbjct: 7349 LTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEI 7408
Query: 398 KGTPKPSIKWYRNTVILPITGNLVLSDD--NQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
GTP + W ++ + + ++ + +L +L + D YHC+A N+ G
Sbjct: 7409 SGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTC 7468
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV---ED 512
S + ++ PPR V K D +V++ +E P S+ W KD ++ E+
Sbjct: 7469 SCSVKFKE----PPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESEN 7524
Query: 513 DRIS-ITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
RIS I I +L + + +++G+Y C ND G S LTV
Sbjct: 7525 TRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 7568
Score = 138 bits (334), Expect = 1e-31
Identities = 104/395 (26%), Positives = 178/395 (45%), Gaps = 29/395 (7%)
Query: 180 QQPQF--ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRD-SEVIPLNENRYEIFDN-G 235
+ P+F + EP+ + V E + C G P ++LW +D +E+ ++ R D+
Sbjct: 8230 EPPRFIKKLEPSRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA 8288
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L +H + D G + C A N AG A S + K +E PP+F P
Sbjct: 8289 VLEMHNLSVEDSGDYTCEAHNAAGSASSSTSL-----KVKE-----PPIFRKKPHP-IET 8337
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHN--GSILIKNVQNSDAGVYT 352
+ V +C G P HV+WY + + ++ I+ N SI I NV +D G Y
Sbjct: 8338 LKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQ 8397
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
C+ N G + + + APP F+ ++ + ++G V +G S+ W+++
Sbjct: 8398 CKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKG 8457
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAI---YHCRAENDGGMIEASAVLTLEQVEIIPP 469
+ + + ++N+ L+ +R + A Y C+ +ND GM E A L++ + P
Sbjct: 8458 EIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE----PA 8513
Query: 470 RIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIR 526
IV KPE + + + C + P S W KDG + D++ I+ + L I
Sbjct: 8514 TIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKII 8573
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
NV+ +D+G Y N G+D+ + L V D +P
Sbjct: 8574 NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVP 8608
Score = 137 bits (331), Expect = 3e-31
Identities = 99/389 (25%), Positives = 175/389 (44%), Gaps = 24/389 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--- 236
+ P F EP +EV G+N FT V G P ++ W R + + + +R I+ T
Sbjct: 6818 EPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAREL-VKGDRCNIYFEDTVAE 6876
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L + + + G + C+ N AG+A S ++ V+ P F+ +
Sbjct: 6877 LELFNIDISQSGEYTCVVSNNAGQA-SCTTRLFVKE---------PAAFLKRLSDHSVEP 6926
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTC 353
+ S++ + T TG V W +G + +E+ I+ IL I N DAG Y+C
Sbjct: 6927 GK-SIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSC 6985
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
++EN G+ + PP F+ A +GD+V C+ GTP+ ++ WY+
Sbjct: 6986 EIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTK 7045
Query: 414 LPITGNLVLSDDNQNLTLL--EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L T N TL+ +V +D Y C+AEN G + V +++ + +PP
Sbjct: 7046 LRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQ-LPPSF 7104
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVT 531
+ +D++ V + C + P + W +DG + +D+ + + + ++ + T
Sbjct: 7105 ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQT 7164
Query: 532 D---TGRYECSAFNDYGRDTASVFLTVKD 557
D +G+Y CSA N G ++S LT ++
Sbjct: 7165 DLSHSGQYSCSASNPLGTASSSARLTARE 7193
Score = 136 bits (328), Expect = 7e-31
Identities = 106/392 (27%), Positives = 172/392 (43%), Gaps = 22/392 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGT-L 237
+ P FE P+ VEV G + FT V G P ++ W + S E++P + D T L
Sbjct: 7759 EPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTEL 7818
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ E + G + C+ N AG A S + V+ P FV F+
Sbjct: 7819 ELFEVQPLESGDYSCLVTNDAGSA-SCTTHLFVKE---------PATFVKRLAD-FSVET 7867
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQ 354
+ ++ + T TG P V+W + + +ER I + +IL I D Y+C
Sbjct: 7868 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 7927
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+EN G+ + V PP FI + A+IG+ CK GTP+ I WY+ L
Sbjct: 7928 IENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKL 7987
Query: 415 PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ N +L + +V D Y C+A+N G + +SAVL +++ + +PP
Sbjct: 7988 RSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERK-LPPFFA 8046
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTD 532
K +D+ V C I P + W KDG + +D + + + ++ + TD
Sbjct: 8047 RKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTD 8106
Query: 533 ---TGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G+Y CSA N G ++S L + ++ +P
Sbjct: 8107 QSHIGQYNCSASNPLGTASSSAKLILSEHEVP 8138
Score = 134 bits (325), Expect = 2e-30
Identities = 113/397 (28%), Positives = 173/397 (43%), Gaps = 37/397 (9%)
Query: 181 QPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TL 237
+P + EP + VE GE A C G P I W ++ + F N +L
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
++++ + +D G + C A N G S +I RK PP F ++ ++
Sbjct: 8005 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKL-------PPFFA----RKLKDVH 8053
Query: 298 ET---SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQ----HNGSIL-IKNVQNSDAG 349
ET V F+C G V+WY +G +LL + LQ HN + L I S G
Sbjct: 8054 ETLGFPVAFECRINGSEPLQVSWYKDG--VLLKDDANLQTSFVHNVATLQILQTDQSHIG 8111
Query: 350 VYTCQVENIHGKISASVPL---EVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIK 406
Y C N G S+S L E PP F + P + +G++ F C GT I
Sbjct: 8112 QYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKIT 8171
Query: 407 WYRNTVILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
W ++ + GN + L ++ LT+L+V + D Y C A N G SA L +++
Sbjct: 8172 WAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQE- 8230
Query: 465 EIIPPRIVLKPEDMDAFKETS-VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSL 523
PPR + K E K+ + C+I P + W KD + I E + ++ + S+
Sbjct: 8231 ---PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSV 8287
Query: 524 II---RNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ N+SV D+G Y C A N G ++S L VK+
Sbjct: 8288 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE 8324
Score = 134 bits (324), Expect = 2e-30
Identities = 110/436 (25%), Positives = 180/436 (41%), Gaps = 25/436 (5%)
Query: 135 CDCSILWFIRMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVS 194
C+ S+ F+ LE E + + Y A+ H + F D V
Sbjct: 7807 CNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVE 7866
Query: 195 FGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLM-VHEANENDDGLFEC 252
G V TG P + W++D +I +E + + T++ + E+ D + C
Sbjct: 7867 TGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSC 7926
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+ +N AG+ + ++ PP F+ + A I E + + C G P+
Sbjct: 7927 LIENEAGQDICEALVSVLE----------PPYFIEPLEHVEAVIGEPATL-QCKVDGTPE 7975
Query: 313 PHVAWYFNGERMLLNERIILQHN---GSILIKNVQNSDAGVYTCQVENIHGKISASVPL- 368
++WY ++ +Q S++I V +SD G Y+C+ +N G +++S L
Sbjct: 7976 IRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLV 8035
Query: 369 --EVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDN 426
E PP F + +G V F C+ G+ + WY++ V+L NL S +
Sbjct: 8036 IKERKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVH 8095
Query: 427 QNLTLLEVTRDDDAI--YHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKET 484
TL + D I Y+C A N G +SA L L + E +PP LKP +D
Sbjct: 8096 NVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-VPPFFDLKPVSVDLALGE 8154
Query: 485 SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRNVSVTDTGRYECSAF 541
S C + P I W KD I +T++ +L + V D G+Y C A
Sbjct: 8155 SGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYAS 8214
Query: 542 NDYGRDTASVFLTVKD 557
N G+D+ S L V++
Sbjct: 8215 NIAGKDSCSAHLGVQE 8230
Score = 129 bits (312), Expect = 6e-29
Identities = 94/379 (24%), Positives = 159/379 (41%), Gaps = 22/379 (5%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLMVHEANE 244
+P + V+ G CV TG P W +D + + + F N +L + A
Sbjct: 7577 KPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM 7636
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D GL+ KN GK++ + + R PP F+ K I SV+ +
Sbjct: 7637 SDKGLYSFEVKNSVGKSNCTVSVHVSDRIV-------PPSFIRK-LKDVNAILGASVVLE 7688
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV---QNSDAGVYTCQVENIHGK 361
C +G V W+ +G ++ + + ++ N+ + SD G+YTC N+ G
Sbjct: 7689 CRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGS 7748
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT--VILPITGN 419
S L V PPSF P + + G ++ FT +GTP +KW++ + ++ + N
Sbjct: 7749 DECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCN 7808
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ L D L L EV + Y C ND G + L +++ P V + D
Sbjct: 7809 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKE----PATFVKRLADFS 7864
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNV---SVTDTGRY 536
+ + + PP S+ W KD I + +R SIT+ I + ++ D +Y
Sbjct: 7865 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQY 7924
Query: 537 ECSAFNDYGRDTASVFLTV 555
C N+ G+D ++V
Sbjct: 7925 SCLIENEAGQDICEALVSV 7943
Score = 128 bits (308), Expect = 2e-28
Identities = 105/382 (27%), Positives = 161/382 (42%), Gaps = 25/382 (6%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN--END 246
+D V G++ + TG + W +D I +E + T ++ N + D
Sbjct: 6920 SDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRD 6979
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
G + C +N AG+ +V + PP FV+ + A + + SV C
Sbjct: 6980 AGQYSCEIENEAGR---DVCGALV-------STLEPPYFVTELEPLEAAVGD-SVSLQCQ 7028
Query: 307 ATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQN-SDAGVYTCQVENIHGKIS 363
G P+ V+WY ++ R +N + L+ N N +D+G YTC+ EN G S
Sbjct: 7029 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 7088
Query: 364 ASVPLEVTA---PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
+ + PPSF + +G V TC+ G+ + WYR+ V+L NL
Sbjct: 7089 SKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENL 7148
Query: 421 VLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
S D+ L +L+ Y C A N G +SA LT + + P +KP +
Sbjct: 7149 QTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKK-SPFFDIKPVSI 7207
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGR 535
D S C + P I W KD I +IT +G+ L I V D+G+
Sbjct: 7208 DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQ 7267
Query: 536 YECSAFNDYGRDTASVFLTVKD 557
Y C A ND G+D S L+VK+
Sbjct: 7268 YTCQATNDVGKDMCSAQLSVKE 7289
Score = 126 bits (304), Expect = 5e-28
Identities = 98/392 (25%), Positives = 168/392 (42%), Gaps = 25/392 (6%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLM-VH 240
+F ND + G+ + TG P + W ++ V P + ++ +
Sbjct: 8796 KFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIP 8855
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ D G + C +N +GK S A++++ PP FV + + + S
Sbjct: 8856 SSTVEDAGQYNCYIENASGK-DSCSAQILILE---------PPYFVKQLEPVKVSVGD-S 8904
Query: 301 VMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKN-VQNSDAGVYTCQVEN 357
C G P+ V+WY ++ ++ ++N + L+ N V +D+G Y C+ EN
Sbjct: 8905 ASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAEN 8964
Query: 358 IHGKISASVPLEVTA---PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
G++SAS L V PPSF + +G V F C G+ S+ WY++ L
Sbjct: 8965 SVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPL 9024
Query: 415 PITGNLVLS--DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ N+ S D+ L + + R Y C A N G +SA L L + + PP
Sbjct: 9025 KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKN-PPFFD 9083
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVS 529
++ +DA S C + P + W KD I + I+ + + L + V
Sbjct: 9084 IRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVD 9143
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
D+G+Y C A N+ G+D+ + L +K+ L+P
Sbjct: 9144 KGDSGQYTCYAVNEVGKDSCTAQLNIKERLIP 9175
Score = 124 bits (300), Expect = 2e-27
Identities = 94/361 (26%), Positives = 165/361 (45%), Gaps = 26/361 (7%)
Query: 210 APEILWLRDSEVIPLNENRYEIFDNGT--LMVHEANEND-DGLFECMAKNVAGKAHSKPA 266
A E+ W +++++P +E + D T L++ + N D G + C A N +GK +
Sbjct: 4315 AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAK 4374
Query: 267 KMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLL 326
+V+R A K P+ V+ AK F C P W+ G +
Sbjct: 4375 LTVVKRAAPVIKRKIEPLEVALGH--LAK-------FTCEIQSAPNVRFQWFKAGREIYE 4425
Query: 327 NERIILQHN---GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA--PPSFIVVPT 381
+++ ++ + S+ I Q D G YTC+ N +G +S + L VT PP+F+ P
Sbjct: 4426 SDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPK 4485
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSD-DNQN-LTLLEVTRDDD 439
+ T +G F C GTP W ++ L + N +SD +N++ L L +T D
Sbjct: 4486 SLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDR 4545
Query: 440 AIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPAS 499
+Y C+A N G + + E + I P + + E + + V + C+++ +
Sbjct: 4546 GVYSCKASNKFG----ADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVT 4601
Query: 500 IDWRKDGSRIV--EDDRISI-TVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ W KDG ++ +D +I I +L I + D+G Y C+A N+ G + S +TV+
Sbjct: 4602 VTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVR 4661
Query: 557 D 557
+
Sbjct: 4662 E 4662
Score = 123 bits (297), Expect = 4e-27
Identities = 99/391 (25%), Positives = 168/391 (42%), Gaps = 26/391 (6%)
Query: 180 QQP-QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--T 236
Q+P Q + V+V+ + CV G P ++ WL+D + I + F+N +
Sbjct: 6065 QEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVAS 6124
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ + D G + +N G + ++ + PP F K K+
Sbjct: 6125 FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNI-------PPSFTKKLTK-MDKV 6176
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIIL---QHNGSILIKNVQNSDAGVYTC 353
+S+ +C +G W+ +G+ + + + L + + S+ + N++ D YTC
Sbjct: 6177 LGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTC 6236
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
+V N+ G + S L V PPSF+V P Q AI V F KGTP IKW+++ V
Sbjct: 6237 KVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVE 6296
Query: 414 LPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
L ++G + L L L V Y C ND G + +L + + PP+
Sbjct: 6297 L-VSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE----PPK 6351
Query: 471 IVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLII---R 526
V K E K S ++ C+I P + W ++ + D+ +T I S+ +
Sbjct: 6352 FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 6411
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
N+S D+G + C A N G + S + VK+
Sbjct: 6412 NLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 6442
Score = 122 bits (294), Expect = 9e-27
Identities = 97/377 (25%), Positives = 161/377 (42%), Gaps = 28/377 (7%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P F S P + G+ A F C TG P E +W +D + + N ++I D + E
Sbjct: 4478 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPN-WKISDAENKHILE 4536
Query: 242 ANE---NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ D G++ C A N G A A++I+ K P F+ + + IN+
Sbjct: 4537 LSNLTIQDRGVYSCKASNKFG-ADICQAELIIIDK---------PHFIKELEPVQSAINK 4586
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHN-GSILIKNVQNSDAGVYTCQV 355
V +C K V W +G+++ + +I + ++ I + D+G Y C
Sbjct: 4587 -KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTA 4645
Query: 356 ENIHGKISASVPLEVTAPPSFI-VVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N G S S + V PPSF+ V + + G++ CK KG+P + W++N L
Sbjct: 4646 SNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKEL 4705
Query: 415 PITGNLVLSDDNQN--LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ + + N L + +V +D Y C A ND G S + +++ PP +
Sbjct: 4706 SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE----PPSFI 4761
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI---IRNVS 529
E D + T+ + CE+ P I W KD +I + + SL+ I + +
Sbjct: 4762 KTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFN 4821
Query: 530 VTDTGRYECSAFNDYGR 546
D G YEC N+ G+
Sbjct: 4822 SADVGEYECVVANEVGK 4838
Score = 122 bits (293), Expect = 1e-26
Identities = 95/389 (24%), Positives = 161/389 (41%), Gaps = 23/389 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+ P F +P+ +E G + C G P + W +D + + + +N +
Sbjct: 8324 EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSI 8383
Query: 240 HEANEN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
H N + D G ++C A N G S + KA PP FV +
Sbjct: 8384 HILNVDAADIGEYQCKATNDVG---SDTCVGSIALKA-------PPRFVKKLSDISTVVG 8433
Query: 298 ETSVMFDCTATGFPKPHVAWYFN-GERMLLNERIILQHNGSIL---IKNVQNSDAGVYTC 353
+ V T G V W+ + GE + ++ I + ++ +I V+ ++AG YTC
Sbjct: 8434 K-EVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 8492
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
Q++N G L V P + + P + GD C GTP+ S KW+++
Sbjct: 8493 QIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKE 8552
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L +S N+ L ++ V D +Y +N G +A L + +PP
Sbjct: 8553 LTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSD-RTVPPSF 8611
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNV 528
K ++ + +SV M C++ PP S+ W +G+ I + T+ +L + +
Sbjct: 8612 TRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNML 8671
Query: 529 SVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+D+G Y C A N G D S LTV++
Sbjct: 8672 EESDSGDYTCIATNMAGSDECSAPLTVRE 8700
Score = 121 bits (291), Expect = 2e-26
Identities = 91/379 (24%), Positives = 163/379 (43%), Gaps = 23/379 (6%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--LMVHEANENDDG 248
++V+ G+ A G P + W +D + ++ F N L + A +D G
Sbjct: 4953 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSG 5012
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
+ N G + + ++ R AP F + P + + + DC
Sbjct: 5013 QYTFEISNEVGSSSCETTFTVLDRDI------AP--FFTKPLRNVDSVVNGTCRLDCKIA 5064
Query: 309 GFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
G V+W+ +G+ + ++R ++ S+ I V +DAG +TC+ N G +S
Sbjct: 5065 GSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS 5124
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
L V PPSF+ P ++ + G V +G+ +I+W++ L G+ ++ +
Sbjct: 5125 GALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKE 5184
Query: 426 --NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
+L L V D Y C+ N G +E SA L +++ P V K E K+
Sbjct: 5185 ALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKE----PATFVEKLEPSQLLKK 5240
Query: 484 -TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECS 539
+ Q+ C++ PP I W + I E + ++ + S L + +V + D+G Y C
Sbjct: 5241 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 5300
Query: 540 AFNDYGRDTASVFLTVKDN 558
A N+ G D S + VK++
Sbjct: 5301 AQNEAGSDHCSSIVIVKES 5319
Score = 120 bits (288), Expect = 5e-26
Identities = 102/389 (26%), Positives = 167/389 (42%), Gaps = 27/389 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI----FDNGTL 237
P F +P+ V G + + C +G P E++W++D + + N +++I FD +L
Sbjct: 7385 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVR-NSKKFKITSKHFDT-SL 7442
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A N G S V+ K PP FV I
Sbjct: 7443 HILNLEASDVGEYHCKATNEVG---SDTCSCSVKFKE-------PPRFVKKLSDTSTLIG 7492
Query: 298 ETSVMFDCTATGFPKPHVAWYFN-GE--RMLLNERIILQHN-GSILIKNVQNSDAGVYTC 353
+ +V GF V W + GE R N RI N ++ + + + S++G Y C
Sbjct: 7493 D-AVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 7551
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
Q++N G S L V P I P T G+ C GTP+ S KW+++
Sbjct: 7552 QIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRE 7611
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L ++ N+ +L + D +Y +N G + + + I+PP
Sbjct: 7612 LSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD-RIVPPSF 7670
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSV- 530
+ K +D++A SV + C + P S+ W +DG+ IV + + ++ N+S+
Sbjct: 7671 IRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLL 7730
Query: 531 --TDTGRYECSAFNDYGRDTASVFLTVKD 557
+DTG Y C A N G D S LTV++
Sbjct: 7731 EPSDTGIYTCVAANVAGSDECSAVLTVQE 7759
Score = 119 bits (287), Expect = 6e-26
Identities = 99/388 (25%), Positives = 163/388 (42%), Gaps = 26/388 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLM 238
+P F E V+ + + C + + W +D + +P ++ F++ TL
Sbjct: 4570 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLE 4629
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ A D G + C A N AG + S A + VR PP FV + +
Sbjct: 4630 IPLAKLKDSGTYVCTASNEAGSS-SCSATVTVRE---------PPSFVKKVDPSYLMLPG 4679
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL-IKNVQNSDAGVYTCQV 355
S C G P V W+ N + + + R+ ++ +IL I +V+ D+G Y+C+
Sbjct: 4680 ESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEA 4739
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
N G S S + + PPSFI + G N C+ GT I W+++ +
Sbjct: 4740 VNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIR 4799
Query: 416 ITGNLVLSDDNQNLTLLEV---TRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ L ++L LE+ D Y C N+ G A L++ PP V
Sbjct: 4800 SSKKYRLF-SQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE----PPTFV 4854
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNVS 529
K +D+ A +V + + P S+ W K I ED +I ++ + LII +V
Sbjct: 4855 KKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQ 4914
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKD 557
++ G+Y C A N+ G T+ L VK+
Sbjct: 4915 ISFGGKYTCLAENEAGSQTSVGELIVKE 4942
Score = 119 bits (287), Expect = 6e-26
Identities = 90/387 (23%), Positives = 161/387 (41%), Gaps = 26/387 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDN-GTLMV 239
P F + ++ G C+ G I W +D + I +E ++ DN L +
Sbjct: 5602 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 5661
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + C A N AG H++ + + ++ PP FV PQ + N T
Sbjct: 5662 SQLEGTDSGTYTCSATNKAG--HNQCSGHLTVKE--------PPYFVEKPQSQDVNPN-T 5710
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIK--NVQNSDAGVYTCQVE 356
V G + W+ + + + R + + + S ++ + +D+G Y CQ+
Sbjct: 5711 RVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS 5770
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWY--RNTVI 413
N G ++ L V PP FI P+ + G + F C+ GTPK + WY N +
Sbjct: 5771 NDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEIT 5830
Query: 414 LPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ D + ++ Y C A ND G S L +++ PP +
Sbjct: 5831 AIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE----PPTFIR 5886
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT---VIGSLIIRNVSV 530
+ + ++ K + V++ CE+ PP + W K+ I + ++T + +L I
Sbjct: 5887 ELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDP 5946
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKD 557
+DTG Y+C N+ G + S + +K+
Sbjct: 5947 SDTGEYQCIVSNEGGSCSCSTRVALKE 5973
Score = 115 bits (276), Expect = 1e-24
Identities = 92/411 (22%), Positives = 172/411 (41%), Gaps = 33/411 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TLMV 239
P F + G + + C G + W + I F + TL +
Sbjct: 6727 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 6786
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ + +D G + C+A NVAG + A + V+ PP FV P+ +
Sbjct: 6787 NSLDSSDMGNYTCVAANVAGSDECR-AVLTVQE---------PPSFVKEPEP-LEVLPGK 6835
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTCQVE 356
+V F G P V W+ ++ +R + ++ + N+ S +G YTC V
Sbjct: 6836 NVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVS 6895
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ S + L V P +F+ ++ + G ++ GT S+ W ++ +
Sbjct: 6896 NNAGQASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6955
Query: 417 TG--NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-TLEQVEIIPPRIVL 473
+ N+V ++ L +L T+ D Y C EN+ G A++ TLE PP V
Sbjct: 6956 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE-----PPYFVT 7010
Query: 474 KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI--VEDDRISITV-IGSLIIRNVSV 530
+ E ++A SV + C++ P ++ W K +++ + R T + +L+ V++
Sbjct: 7011 ELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNI 7070
Query: 531 TDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAMRDVDQAI 581
D+G Y C A N G ++ +++ LP + + ++D++Q +
Sbjct: 7071 NDSGEYTCKAENSIGTASSKTVFRIQERQLPP------SFARQLKDIEQTV 7115
Score = 114 bits (274), Expect = 2e-24
Identities = 86/372 (23%), Positives = 145/372 (38%), Gaps = 22/372 (5%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTLMVHEANENDDGLF 250
V+ GE C G P + W +D +++ ++ F N +L + D G +
Sbjct: 6642 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTY 6701
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+N GK+ S A + V +A PP F K + S + +C G
Sbjct: 6702 TFQVQNNVGKS-SCTAVVDVSDRA------VPPSFTRR-LKNTGGVLGASCILECKVAGS 6753
Query: 311 PKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTCQVENIHGKISASVP 367
VAW+ +++ + + ++ + ++ +SD G YTC N+ G
Sbjct: 6754 SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 6813
Query: 368 LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT--VILPITGNLVLSDD 425
L V PPSF+ P + G NV FT +GTP + W+R ++ N+ D
Sbjct: 6814 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 6873
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
L L + Y C N+ G + L +++ P + + D S
Sbjct: 6874 VAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE----PAAFLKRLSDHSVEPGKS 6929
Query: 486 VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECSAFN 542
+ + P S+ W+KDG I ++ +I L I N + D G+Y C N
Sbjct: 6930 IILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIEN 6989
Query: 543 DYGRDTASVFLT 554
+ GRD ++
Sbjct: 6990 EAGRDVCGALVS 7001
Score = 112 bits (270), Expect = 7e-24
Identities = 96/403 (23%), Positives = 160/403 (39%), Gaps = 24/403 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFD--NGTL 237
+ P F ++P +V G G I W + ++ + + Y + +L
Sbjct: 5131 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 5190
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
++ +D G + C NVAG A + V K PA V P + K +
Sbjct: 5191 ELYLVKTSDSGTYTCKVSNVAGGVECS-ANLFV-------KEPATFVEKLEPSQLLKKGD 5242
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQ 354
T + C TG P + W+ N + + + ++ + + +V D+G Y C+
Sbjct: 5243 ATQLA--CKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 5300
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
+N G S + V P F + +V + GTP I W+++ IL
Sbjct: 5301 AQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 5360
Query: 415 PITGNL--VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ D +L +L+ D Y CR N+ G SA +TL + PP +
Sbjct: 5361 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLRE----PPSFI 5416
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNVS 529
K E + + + ++ P ++ W KD I EDD I +T + SL + +
Sbjct: 5417 KKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIE 5476
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQ 572
V G+Y C A ND G S L+VK+ + V+I +TQ
Sbjct: 5477 VKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQ 5519
Score = 109 bits (262), Expect = 7e-23
Identities = 96/390 (24%), Positives = 160/390 (41%), Gaps = 25/390 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFD-NGTLM 238
+ P F S P VE C +G P E++W +D + + +Y+I N
Sbjct: 6442 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLR-SSKKYKIASKNFHTS 6500
Query: 239 VHEAN--ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+H N +D G + C A+N G S V+ K PP FVS
Sbjct: 6501 IHILNVDTSDIGEYHCKAQNEVG---SDTCVCTVKLKE-------PPRFVSKLNSLTVVA 6550
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
E + + + G V W E ++ N RI N + L + ++AG Y
Sbjct: 6551 GEPAEL-QASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 6609
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
CQ++N G L V P + T +G+ CK GTP+ S++WY++
Sbjct: 6610 CQIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGK 6669
Query: 413 ILPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
+L + S N+ +L +L V R D Y + +N+ G +AV+ + +PP
Sbjct: 6670 LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPS 6728
Query: 471 IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRN 527
+ ++ S + C++ P S+ W + ++IV + T + +L + +
Sbjct: 6729 FTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNS 6788
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +D G Y C A N G D LTV++
Sbjct: 6789 LDSSDMGNYTCVAANVAGSDECRAVLTVQE 6818
Score = 109 bits (261), Expect = 9e-23
Identities = 94/383 (24%), Positives = 157/383 (40%), Gaps = 25/383 (6%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEAN 243
E ++V+ G+ A +G W +D + + L ++Y+I T L +
Sbjct: 5511 EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLG-SKYKISVTDTVSILKIISTE 5569
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
+ D G + +N G++ K A++ V PP F K+ I + +
Sbjct: 5570 KKDSGEYTFEVQNDVGRSSCK-ARINVLDLI------IPPSFTKK-LKKMDSIKGSFIDL 5621
Query: 304 DCTATGFPKPHVAWYFNGERMLLNER--IILQHNGSIL-IKNVQNSDAGVYTCQVENIHG 360
+C G + W+ + + + +E+ N + L I ++ +D+G YTC N G
Sbjct: 5622 ECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 5681
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NTVILPITGN 419
S L V PP F+ P +Q V GT +IKW++ N +
Sbjct: 5682 HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 5741
Query: 420 LVLSDD-NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
V DD + +L L D Y C+ ND G + A L +++ PP+ + KP +
Sbjct: 5742 SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE----PPQFIKKPSPV 5797
Query: 479 DAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVS---VTDTG 534
+ S C+I P + W DG+ I + I+ I L +S V ++G
Sbjct: 5798 LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSG 5857
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A ND G + S+ L VK+
Sbjct: 5858 TYVCEARNDAGTASCSIELKVKE 5880
Score = 107 bits (257), Expect = 3e-22
Identities = 97/388 (25%), Positives = 160/388 (41%), Gaps = 26/388 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN---GTLM 238
P + + +EV+ G A FTC P W + I ++ I + +L
Sbjct: 4383 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYISSLE 4441
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ D G + C A N G S A + V E + PP F+S P+ + +
Sbjct: 4442 ILRTQVVDCGEYTCKASNEYGSV-SCTATLTV---TEAY----PPTFLSRPKSLTTFVGK 4493
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSIL-IKNVQNSDAGVYTCQV 355
+ F CT TG P W +G + N +I N IL + N+ D GVY+C+
Sbjct: 4494 -AAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKA 4552
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
N G L + P FI + I V C+ K ++ W ++ LP
Sbjct: 4553 SNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLP 4612
Query: 416 ITGNLVLSDDNQNLTL-LEVTR-DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ + +++ TL + + + D Y C A N+ G SA +T+ + PP V
Sbjct: 4613 PGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE----PPSFVK 4668
Query: 474 KPE-DMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVS 529
K + S ++ C+++ P + W K+ + E + + + + S L I +V
Sbjct: 4669 KVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVK 4728
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTVKD 557
V D+G Y C A ND G D+ S + +K+
Sbjct: 4729 VEDSGSYSCEAVNDVGSDSCSTEIVIKE 4756
Score = 106 bits (255), Expect = 5e-22
Identities = 111/441 (25%), Positives = 186/441 (42%), Gaps = 39/441 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI--FDNGT-LM 238
P F+ V+ GE+A F C TG ++ W +DS I + +Y+I +N L
Sbjct: 9080 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIR-SGGKYQISYLENSAHLT 9138
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
V + ++ D G + C A N GK S A++ ++ + PP F + +
Sbjct: 9139 VLKVDKGDSGQYTCYAVNEVGK-DSCTAQLNIKERL------IPPSFTKRLSETVEETEG 9191
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSIL-IKNVQNSDAGVYTCQV 355
S + G VAWY N + N I ++N +L ++ +DAG+YTC+V
Sbjct: 9192 NSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKV 9251
Query: 356 ENIHGKI---SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NT 411
N G S+ V E PP F T T G+ V +C +G+ I+W +
Sbjct: 9252 SNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 9311
Query: 412 VILPITG-NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
I P + + L L +V + D Y C+A N G + +T++ + P
Sbjct: 9312 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 9371
Query: 471 -----------IVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISIT 518
V +P+ + ++T+ ++ P ++ W K R + + R+ I
Sbjct: 9372 TKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIH 9431
Query: 519 VIGS---LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV----KDNLLPGDAYVNIALT 571
G L IR+ + TD+G Y C AFN++G ++V L V K + GD + T
Sbjct: 9432 QKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKT 9491
Query: 572 QAM-RDVDQAIERTVDQLFKN 591
+ + + E + +L KN
Sbjct: 9492 PILKKGAGEEEEIDIMELLKN 9512
Score = 106 bits (254), Expect = 6e-22
Identities = 90/386 (23%), Positives = 164/386 (42%), Gaps = 28/386 (7%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDN-GTLMVHEANE 244
EP+ + + G+ C TG P +I W D E+ +++R ++ L + +
Sbjct: 5233 EPSQL-LKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGI 5291
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G + C A+N AG H + +++ +++ P+ V + E VM
Sbjct: 5292 EDSGEYMCEAQNEAGSDHC--SSIVIVKESPYFTKEFKPIEV---------LKEYDVMLL 5340
Query: 305 CTATGFPKPHVAWYFNGERMLLNER----IILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
G P + W F +L + R I H S+ I +DAG Y C+V N G
Sbjct: 5341 AEVAGTPPFEITW-FKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 5399
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
S + + PPSFI + +++ G F KG+ ++ W +++ + N+
Sbjct: 5400 SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNI 5459
Query: 421 VLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
++ +N +L L + D Y C+A+ND G+ SA+L++++ P I + +
Sbjct: 5460 RMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE----PATITEEAVSI 5515
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVT---DTGR 535
D + + + + W KDG + + I+V ++ I + T D+G
Sbjct: 5516 DVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGE 5575
Query: 536 YECSAFNDYGRDTASVFLTVKDNLLP 561
Y ND GR + + V D ++P
Sbjct: 5576 YTFEVQNDVGRSSCKARINVLDLIIP 5601
Score = 105 bits (253), Expect = 8e-22
Identities = 87/388 (22%), Positives = 155/388 (39%), Gaps = 27/388 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--L 237
+ P F +P + F + G P +I W +D + + + T L
Sbjct: 6255 EPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFL 6314
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ-KRFAKI 296
++ + + G + C N G + S ++V PP FV + + K
Sbjct: 6315 NLYSVDASKTGQYTCHVTNDVG-SDSCTTMLLVTE---------PPKFVKKLEASKIVKA 6364
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI---KNVQNSDAGVYTC 353
++S + +C G P+ V W+ N + +++ + S+ + N+ D+G + C
Sbjct: 6365 GDSSRL-ECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFIC 6423
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
+ +N G S S + V PP F P + V C+ GTP + WY++
Sbjct: 6424 EAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQ 6483
Query: 414 LPITGNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L + ++ N ++ +L V D YHC+A+N+ G + V T++ E PPR
Sbjct: 6484 LRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG--SDTCVCTVKLKE--PPRF 6539
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIV-EDDRISITV---IGSLIIRN 527
V K + ++ IE P + W K+ ++ E + I IT + +L
Sbjct: 6540 VSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAK 6599
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ G+Y C ND G + L V
Sbjct: 6600 AEPANAGKYICQIKNDGGMEENMATLMV 6627
Score = 103 bits (247), Expect = 4e-21
Identities = 106/439 (24%), Positives = 159/439 (36%), Gaps = 30/439 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM- 238
+ P F ++ G NA+ C +G EI W +D + I + +Y +F +L+
Sbjct: 4756 EPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI-RSSKKYRLFSQKSLVC 4814
Query: 239 --VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N D G +EC+ N GK H PP FV A
Sbjct: 4815 LEIFSFNSADVGEYECVVANEVGKCGCMAT----------HLLKEPPTFVKKVDDLIALG 4864
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI---LIKNVQNSDAGVYTC 353
+T V G V W E + + +I + + + +I +VQ S G YTC
Sbjct: 4865 GQT-VTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTC 4923
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVI 413
EN G ++ L V P I GD GTP+ KWY++
Sbjct: 4924 LAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4983
Query: 414 LPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
L + +S N L D Y N+ G T+ +I P
Sbjct: 4984 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP--F 5041
Query: 472 VLKP-EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRN 527
KP ++D+ + ++ C+I P + W KDG I DR I + SL I
Sbjct: 5042 FTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIR 5101
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKDN----LLPGDAYVNIALTQAMRDVDQAIER 583
V + D G + C A N G +S L V++ PG V ++ Q
Sbjct: 5102 VDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTP 5161
Query: 584 TVDQLFKNRSAVVNIGDLY 602
+ FK +V+ G Y
Sbjct: 5162 LTIRWFKGNKELVSGGSCY 5180
Score = 77.4 bits (182), Expect = 3e-13
Identities = 59/180 (32%), Positives = 75/180 (41%), Gaps = 10/180 (5%)
Query: 388 GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLL--EV-TRDDDAIYHC 444
GD V T T + WY ++P D TL+ +V T D Y C
Sbjct: 4303 GDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVC 4360
Query: 445 RAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRK 504
A ND G SA LT+ V+ P I K E ++ + CEI+S P W K
Sbjct: 4361 EALNDSGKTATSAKLTV--VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK 4418
Query: 505 DGSRIVEDDRISIT---VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
G I E D+ SI I SL I V D G Y C A N+YG + + LTV + P
Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478
Score = 74.9 bits (176), Expect = 2e-12
Identities = 57/232 (24%), Positives = 100/232 (43%), Gaps = 10/232 (4%)
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG----NLVLSDDN 426
T P+F + + G F G P P + W+R+ ++ + + SD
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 427 QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSV 486
LT+ VT+ + Y +A N G ++A L L + E PP V + + M + + V
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAEL-LVKAETAPPNFVQRLQSMTVRQGSQV 121
Query: 487 QMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFND 543
++ + +P + + +DG+ I I+ G SL+I D+G Y +A N
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 544 YGRDTASVFLTVK-DNLLPGDAYVNIALTQAMRDVDQA-IERTVDQLFKNRS 593
GR T++ L V+ + +P I T + + Q IE+ ++ F RS
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARS 233
Score = 73.7 bits (173), Expect = 4e-12
Identities = 95/399 (23%), Positives = 159/399 (39%), Gaps = 38/399 (9%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG---TLMV 239
+F D++V + A+F C + EP + W++D + + + + R +I L++
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3116
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+D G + VAG + AK+ V + +S V V Q+ + E
Sbjct: 3117 PSTRMSDAGKYTV----VAG-GNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRA---VVEF 3168
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
V D + K + F + ++ ++ + + I + SDAG YT +
Sbjct: 3169 EVNEDDVDAHWYKDGIEINFQVQER--HKYVVERRIHRMFISETRQSDAGEYTF----VA 3222
Query: 360 GKISASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPIT 417
G+ +SV L V AP V+ Q + G F G P+P I WY+ +L
Sbjct: 3223 GRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTG 3282
Query: 418 GNLVLSDDNQNLTLL--EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII-------- 467
D Q TLL E +D A+Y C A+ND G+ SA L++E E++
Sbjct: 3283 FKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPV 3342
Query: 468 -PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SL 523
PP I+ +D + + C + S + W +I +T L
Sbjct: 3343 YPPAIITPLQDTVTSEGQPARFQCRV-SGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQL 3401
Query: 524 IIRNVSVTDTGRYECSAFNDYGR--DTASVFLTVKDNLL 560
I D G Y A N G+ TA++ L +++L
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESIL 3440
Score = 72.9 bits (171), Expect = 7e-12
Identities = 61/206 (29%), Positives = 95/206 (46%), Gaps = 16/206 (7%)
Query: 178 PCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT- 236
P + P F+ V VS GE +C G I WL+ I ++ F +GT
Sbjct: 9269 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTA 9328
Query: 237 -LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRK---AEEHKSPAPP---VFVSTP 289
L + + + D G + C A NVAG +K +K+ ++ K A K A FVS P
Sbjct: 9329 VLELRDVAKADSGDYVCKASNVAGSDTTK-SKVTIKDKPAVAPATKKAAVDGRLFFVSEP 9387
Query: 290 QKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNG---SILIKNVQ 344
Q + +T+ F G P P+V W G+ LN+ R+ + G + I++
Sbjct: 9388 QS-IRVVEKTTATFIAKVGGDPIPNVKW-TKGKWRQLNQGGRVFIHQKGDEAKLEIRDTT 9445
Query: 345 NSDAGVYTCQVENIHGKISASVPLEV 370
+D+G+Y C N HG+I ++V L+V
Sbjct: 9446 KTDSGLYRCVAFNEHGEIESNVNLQV 9471
Score = 70.5 bits (165), Expect = 4e-11
Identities = 52/211 (24%), Positives = 92/211 (43%), Gaps = 24/211 (11%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TLMV 239
P F E ++ ++S G+ A + G P P+I W + ++ + + +FD +L++
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLII 3562
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKS----------------PAPP 283
D+G + CMA N GK A + + K E HK P PP
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICS-AYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3621
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN----GSIL 339
F+ K +F+ T G P P V W+ +++ + + HN G+ +
Sbjct: 3622 HFLKE-LKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3680
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
+ + Q D+G+Y C+ EN+ G+ + + L V
Sbjct: 3681 VNDPQREDSGLYICKAENMLGESTCAAELLV 3711
Score = 69.7 bits (163), Expect = 6e-11
Identities = 90/377 (23%), Positives = 157/377 (41%), Gaps = 40/377 (10%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--- 236
++ F ++EVS + C + +P E++W + E I + RYEI G
Sbjct: 13388 EEAVFTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEI-IETGRYEILTEGRKRI 13445
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L++ A+ D G + C + K+ V A E F+S PQ +
Sbjct: 13446 LVIQNAHLEDAGNYNCRLPS-----SRTDGKVKVHELAAE--------FISKPQN-LEIL 13491
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGS---ILIKNVQNSDAGVYTC 353
F C+ + P V W + + + ++ + +G +++K+ D G Y
Sbjct: 13492 EGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVV 13550
Query: 354 QVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYRNT- 411
V G A+ L V IVVP T + V F C+ T KW+RN
Sbjct: 13551 MV----GAARAAAHLTVIEKLR-IVVPLKDTRVKEQQEVVFNCEVN-TEGAKAKWFRNEE 13604
Query: 412 VILPITGNLVLSDDN-QNLTLLEVTRDDDAIYHCRAENDGGM-IEASAVLTLEQVEIIPP 469
I + ++L D L + + DD A Y+ N G ++++A L +E+ ++
Sbjct: 13605 AIFDSSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDL--- 13661
Query: 470 RIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIR 526
RIV +D++ ++ SV C++ + ++ W K+G + D+R+S V L I+
Sbjct: 13662 RIVEPLKDIETMEKKSVTFWCKVNRLN-VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIK 13720
Query: 527 NVSVTDTGRYECSAFND 543
+ D G Y +A D
Sbjct: 13721 DCGFPDEGEYIVTAGQD 13737
Score = 68.5 bits (160), Expect = 1e-10
Identities = 74/283 (26%), Positives = 122/283 (43%), Gaps = 29/283 (10%)
Query: 287 STPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGS---ILIKNV 343
+ P K F+C T + +V W + + +++ + +G ++I +
Sbjct: 12416 AVPLKDVTVPERRQARFECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDS 12473
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVP-TNQTAIIGDNVWFTCKAKGTPK 402
Q D GVYT +VE GK S L VT + P +QT G+ F C+ K
Sbjct: 12474 QFDDEGVYTAEVE---GK-KTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCEL-SHEK 12528
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
+ W++N L + +++S + + L + EVT DD I +A+ + E S+
Sbjct: 12529 MHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDD--ISQIKAQ----VKELSSTAQ 12582
Query: 461 LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI 520
L+ +E P +K D A ++ + + CE+ P + W KDG IV + SI
Sbjct: 12583 LKVLE-ADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIVPSPKYSIKAD 12639
Query: 521 G---SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLL 560
G L I+ + D G Y C D G D +TV+ L+
Sbjct: 12640 GLRRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARLI 12678
Score = 65.3 bits (152), Expect = 1e-09
Identities = 51/198 (25%), Positives = 86/198 (43%), Gaps = 9/198 (4%)
Query: 368 LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN--TVILPITGNLVLSDD 425
LE P F++ P + + G F K G P P W+ + ++ T +V+ +D
Sbjct: 1451 LERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKED 1510
Query: 426 N-QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE-IIPPRIVLKPEDMDAFKE 483
Q+L ++ T D + A+N G S +LT+E VE + P V K ++++ +
Sbjct: 1511 GTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEG 1570
Query: 484 TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-----SLIIRNVSVTDTGRYEC 538
+ ++M P I W K+ IV I + G +L I + D+ Y
Sbjct: 1571 SQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTA 1630
Query: 539 SAFNDYGRDTASVFLTVK 556
+A N GRDT + V+
Sbjct: 1631 TAINKAGRDTTRCKVNVE 1648
Score = 64.1 bits (149), Expect = 3e-09
Identities = 81/386 (20%), Positives = 147/386 (38%), Gaps = 40/386 (10%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG--TL 237
+ PQ E V V G+ A F V +G P P+I W ++ +++ + D TL
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRK--AEEHKSPAPPVFVSTPQKRFAK 295
++ EA D ++ C AKN G A + + + + + + + P P + TP +
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT 3356
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIIL---QHNGSILIKNVQNSDAGVYT 352
F C +G V+WY +++ + + + + I D G YT
Sbjct: 3357 SEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYT 3415
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV 412
N G++S++ L + A P I+ + I + F+ + +
Sbjct: 3416 FVASNAVGQVSSTANLSLEA-PESILHERIEQEIEMEMKEFSSSFLSAEEEGLH------ 3468
Query: 413 ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ L LS N+ L LL + +Y + +++ E + + +++V
Sbjct: 3469 ----SAELQLSKINETLELLS----ESPVYSTKFDSEK---EGTGPIFIKEVS------- 3510
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNVS 529
+ D + + +P I W +G + G SLII
Sbjct: 3511 ----NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTK 3566
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
+ D G Y C A NDYG+ S +L +
Sbjct: 3567 LEDEGEYTCMASNDYGKTICSAYLKI 3592
Score = 63.7 bits (148), Expect = 4e-09
Identities = 48/198 (24%), Positives = 92/198 (46%), Gaps = 11/198 (5%)
Query: 283 PVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGS----- 337
P F P + + ++ F+ +GFP P V+W+ +G+ + + +Q + S
Sbjct: 6 PTFTQ-PLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 338 ILIKNVQNSDAGVYTCQVENIHGKISASVPLEV---TAPPSFIVVPTNQTAIIGDNVWFT 394
+ I V +++G Y+ + N G+ +++ L V TAPP+F+ + T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQ 124
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSD--DNQNLTLLEVTRDDDAIYHCRAENDGGM 452
+ G P P +K+YR+ + + + +S D +L + E +D Y A N G
Sbjct: 125 VRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGR 184
Query: 453 IEASAVLTLEQVEIIPPR 470
++A L ++ E +P +
Sbjct: 185 ATSTAELLVQGEEEVPAK 202
Score = 63.3 bits (147), Expect = 6e-09
Identities = 86/357 (24%), Positives = 147/357 (41%), Gaps = 33/357 (9%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DN-GTLMVHEANENDDGL 249
V G +A F G+P PE W ++ I ++ Y + DN L++ + D
Sbjct: 2089 VGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSAS 2148
Query: 250 FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATG 309
A N+AG+ S A ++V+ K F Q AK +T F+C T
Sbjct: 2149 IMVKAINIAGET-SSHAFLLVQAK-------QLITFTQELQDVVAKEKDTMATFEC-ETS 2199
Query: 310 FPKPHVAWYFNGERMLLNERIILQHNGSI---LIKNVQNSDAGVYTC-QVENIHGKISAS 365
P V WY +G + ++ + + + I + SDA Y+C VE+ + K +A
Sbjct: 2200 EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAK 2259
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP-SIKWYRNTVILPITGNLVLSD 424
+ +E A F V Q + ++ + +P+ KWY N V L G ++
Sbjct: 2260 LIVE-GAVVEF--VKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITS 2316
Query: 425 --DNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFK 482
QNLT+ +VT++D Y +I+ +++ P I+ D +
Sbjct: 2317 RRGRQNLTVKDVTKEDQGEY-------SFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCE 2369
Query: 483 ETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV---IGSLIIRNVSVTDTGRY 536
VQ+ ++ S+ W KDG + DR+ I + L+I +++ D G Y
Sbjct: 2370 GDIVQLEVKV-SLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425
Score = 62.1 bits (144), Expect = 1e-08
Identities = 61/215 (28%), Positives = 91/215 (42%), Gaps = 18/215 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE-NRYEI-FDNG-- 235
Q P F V V G A F +G P PE+ W RD +VI + +I F +G
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L + + + G + A N +G+A S A+++V KAE APP FV Q +
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATS-TAELLV--KAE----TAPPNFVQRLQSMTVR 116
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNG---SILIKNVQNSDAGVYT 352
+ V TG P P V +Y +G + + + G S+LI D+G Y+
Sbjct: 117 -QGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII 387
N G+ +++ L V VP +T I
Sbjct: 176 VNATNSVGRATSTAELLVQGEEE---VPAKKTKTI 207
Score = 61.3 bits (142), Expect = 2e-08
Identities = 92/394 (23%), Positives = 158/394 (40%), Gaps = 46/394 (11%)
Query: 158 CYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR 217
C P+S T +K H+L + F S+P ++E+ GE A F C + E P + W R
Sbjct: 13461 CRLPSSRTD---GKVKVHELAAE---FISKPQNLEILEGEKAEFVCSISKESFP-VQWKR 13513
Query: 218 DSEVIPLNENRYEIFDNG---TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKA 274
D + + + ++Y++ +G L+V +A D G + M G A +A
Sbjct: 13514 DDKTLE-SGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAA-----------RA 13557
Query: 275 EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER-IILQ 333
H + + + P K + V+F+C W+ N E + + + IILQ
Sbjct: 13558 AAHLTVIEKLRIVVPLKDTRVKEQQEVVFNC-EVNTEGAKAKWFRNEEAIFDSSKYIILQ 13616
Query: 334 HN--GSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAII-GD 389
+ ++ I++ D Y + N G+ + ++ L V IV P +
Sbjct: 13617 KDLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKK 13676
Query: 390 NVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN--LTLLEVTRDDDAIYHCRAE 447
+V F CK ++KW +N +P + D LT+ + D+ Y A
Sbjct: 13677 SVTFWCKVNRL-NVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAG 13735
Query: 448 NDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGS 507
D + E +L +E P V ED + C++ S A++ W ++G
Sbjct: 13736 QDKSVAE---LLIIE----APTEFVEHLEDQTVTEFDDAVFSCQL-SREKANVKWYRNGR 13787
Query: 508 RIVEDDRISITVIGS---LIIRNVSVTDTGRYEC 538
I E + GS LII++ + D Y C
Sbjct: 13788 EIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC 13821
Score = 60.5 bits (140), Expect = 4e-08
Identities = 74/358 (20%), Positives = 139/358 (38%), Gaps = 36/358 (10%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL 249
DV V+ GE A F C + E P +L+ ++ P + ++ VH D L
Sbjct: 13131 DVTVTAGETATFDCELSYEDIPVEWYLKGKKLEPSD----KVVPRSEGKVHTLTLRDVKL 13186
Query: 250 FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATG 309
+ + K A + V+ PPV + P + + + +C +
Sbjct: 13187 EDAGEVQLTAKDFKTHANLFVKE---------PPVEFTKPLEDQTVEEGATAVLECEVSR 13237
Query: 310 FPKPHVAWYFNGERMLLNERIILQHNG---SILIKNVQNSDAGVYTCQVENIHGKISASV 366
V W+ NG +L +++ + +G ++I + D YTC ++ S
Sbjct: 13238 -ENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKD----FKTSC 13292
Query: 367 PLEVTAP-PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP--ITGNLVLS 423
L V P F+ T+ + F C+ +KW+++ + +++
Sbjct: 13293 NLNVVPPHVEFLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDIISK 13351
Query: 424 DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
+ L + + DD+A Y C S +LT+ + E + +++ +
Sbjct: 13352 GAVRILVINKCLLDDEAEYSCEVRT----ARTSGMLTVLEEEAV---FTKNLANIEVSET 13404
Query: 484 TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYEC 538
++++ CE+ S P A + W K I+E R I G L+I+N + D G Y C
Sbjct: 13405 DTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 13461
Score = 57.6 bits (133), Expect = 3e-07
Identities = 90/381 (23%), Positives = 154/381 (40%), Gaps = 50/381 (13%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEANENDD 247
VEV GE A F + EP W + + + + EI ++G L++H
Sbjct: 12687 VEVFVGETAHFE-IELSEPDVHGQWKLKGQPLTASPD-CEIIEDGKKHILILHNCQLGMT 12744
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
G A N A+ K ++ P +F+ TP + F+C
Sbjct: 12745 GEVSFQAANAKSAANLKVKEL-------------PLIFI-TPLSDVKVFEKDEAKFECEV 12790
Query: 308 TGFPKPHVAWYFNGERMLLNERIILQHNG---SILIKNVQNSDAGVYTCQVENIH--GK- 361
+ PK W + + ++R L +G S++IK+ D Y + E+ H GK
Sbjct: 12791 SREPKTF-RWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKL 12849
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
I + L+ P + ++A+ FT + +KW++N L T ++
Sbjct: 12850 IIEGIRLKFLTPLKDVTAKEKESAV------FTVELSHD-NIRVKWFKNDQRLHTTRSVS 12902
Query: 422 LSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMD 479
+ D+ + ++T +++ DD + R E G + + A LT+ + + P K +D
Sbjct: 12903 MQDEGKTHSITFKDLSIDDTS--QIRVEAMG--MSSEAKLTVLEGD---PYFTGKLQDYT 12955
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRY 536
++ V + CEI S A + W KDG I I G LI++ +D G+Y
Sbjct: 12956 GVEKDEVILQCEI-SKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQY 13014
Query: 537 ECSAFNDYGRDTASVFLTVKD 557
C D G D S L ++D
Sbjct: 13015 TC----DCGTDKTSGKLDIED 13031
Score = 55.2 bits (127), Expect = 1e-06
Identities = 52/190 (27%), Positives = 82/190 (43%), Gaps = 13/190 (6%)
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
KI S +E AP F + + QT G + F + G P P +WY+N V + + +
Sbjct: 2068 KIELSPSME--APKIFERIQS-QTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124
Query: 421 --VLSDDNQ-NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
+DN L + +VT +D A +A N G + A L ++ ++I + +D
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLI--TFTQELQD 2182
Query: 478 MDA-FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRI---SITVIGSLIIRNVSVTDT 533
+ A K+T CE S P + W KDG + E D+ S + L I + +D
Sbjct: 2183 VVAKEKDTMATFECE-TSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDA 2241
Query: 534 GRYECSAFND 543
Y C D
Sbjct: 2242 EDYSCVLVED 2251
Score = 55.2 bits (127), Expect = 1e-06
Identities = 87/376 (23%), Positives = 146/376 (38%), Gaps = 39/376 (10%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH--EANENDDGLFECM 253
G +A+F C+ + A W++D I + I D +H + +D G + C+
Sbjct: 12060 GSSAIFECLVSPSTAITT-WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCV 12118
Query: 254 AKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKP 313
+ + K + AK++V EE P FV T ++ + + C +
Sbjct: 12119 LR-LGNKEKTSTAKLVV----EE----LPVRFVKTLEEEVTVVKGQPLYLSCELN--KER 12167
Query: 314 HVAWYFNGERMLLNE-RIILQHNG---SILIKNVQNSDAGVYTCQVENIHGKISASVPLE 369
V W +G+ ++ RI+ G ++ I + ++DAG YT VEN + +S
Sbjct: 12168 DVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKV 12227
Query: 370 VTAPPSFIVVP-TNQTAIIGDNVWFTCK-AKGTPKPSIKWYRNTVILPITGN---LVLSD 424
V ++V P +Q F C AK T P+IKW++ +P N +L D
Sbjct: 12228 VEVIRDWLVKPIRDQHVKPKGTAIFACDIAKDT--PNIKWFKGYDEIPAEPNDKTEILRD 12285
Query: 425 DNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKET 484
N ++ +D I E +G A L +VE++ P ED+ +++
Sbjct: 12286 GNHLYLKIKNAMPED-IAEYAVEIEGKRYPAKLTLGEREVELLKP-----IEDVTIYEKE 12339
Query: 485 SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECSAF 541
S EI W+ G + I G L +R V + G A
Sbjct: 12340 SASFDAEISEADIPG-QWKLKGELLRPSPTCEIKAEGGKRFLTLRKVKLDQAGEVLYQAL 12398
Query: 542 NDYGRDTASVFLTVKD 557
N + LTVK+
Sbjct: 12399 N----AITTAILTVKE 12410
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 442 YHCRAENDGGMIEASAVLTLE-QVEIIPPRIVLKPEDMDAF---KETSVQMPCEIESVPP 497
+ +AEN G+ + +E Q +++PP + L + ++ T+V+ P I VP
Sbjct: 18407 FRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPV 18466
Query: 498 ASIDWRKDGSRIVEDDRISITV---IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLT 554
+ W DGS I D+ ++ L I+N DTG Y+ + N G T +V LT
Sbjct: 18467 PTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 18526
Query: 555 VKDNLLPGDAYVNI 568
V D P +NI
Sbjct: 18527 VLDVPGPPTGPINI 18540
Score = 54.8 bits (126), Expect = 2e-06
Identities = 38/135 (28%), Positives = 60/135 (44%), Gaps = 3/135 (2%)
Query: 176 DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG 235
++P P S +V V GE+ C +G P+P + W R+ I + + F +G
Sbjct: 937 EIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSG 996
Query: 236 --TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRF 293
LM+ EA D G F C A N AG + + + E ++ A +T +KRF
Sbjct: 997 IARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRF 1056
Query: 294 AKINETSVMFDCTAT 308
+ + VM D + T
Sbjct: 1057 VESRDV-VMTDTSLT 1070
Score = 53.6 bits (123), Expect = 5e-06
Identities = 85/358 (23%), Positives = 146/358 (40%), Gaps = 45/358 (12%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEANEND 246
++ V+ ++AVFT T + W+++ V+ NE +Y I GT L + D
Sbjct: 2715 NLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNE-KYAISVKGTIYSLRIKNCAIVD 2773
Query: 247 DGL--FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+ + F + + H + K+I + K A F E SV D
Sbjct: 2774 ESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVAF------------EVSVSHD 2821
Query: 305 CTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
+ +V + + L++ER + H ++++N+ SDAG YT V + K
Sbjct: 2822 TVPVKWFHKNVEIKPSDKHRLVSERKV--HK--LMLQNISPSDAGEYTAVVGQLECKAKL 2877
Query: 365 SV-PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG--NLV 421
V L +T I VP +TA F C+ PS+ W +N V + ++ +V
Sbjct: 2878 FVETLHITKTMKNIEVPETKTAS------FECEVSHFNVPSM-WLKNGVEIEMSEKFKIV 2930
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ L ++ + +D A Y ND + SA LT + P I +D++A
Sbjct: 2931 VQGKLHQLIIMNTSTEDSAEYTFVCGND----QVSATLT-----VTPIMITSMLKDINAE 2981
Query: 482 KETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI---TVIGSLIIRNVSVTDTGRY 536
++ ++ + + S W K+G I D+ + + SL IRNV D Y
Sbjct: 2982 EKDTITFEVTV-NYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADY 3038
Score = 53.6 bits (123), Expect = 5e-06
Identities = 55/252 (21%), Positives = 98/252 (38%), Gaps = 36/252 (14%)
Query: 273 KAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIIL 332
K + K P+F+ + + + + T G PKP + W+FNG + +
Sbjct: 3493 KFDSEKEGTGPIFIKEVSNADISMGDVATL-SVTVIGIPKPKIQWFFNGVLLTPSADYKF 3551
Query: 333 QHNG---SILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA----------------- 372
+G S++I + D G YTC N +GK S L++ +
Sbjct: 3552 VFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 3611
Query: 373 --------PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLS 423
PP F+ G F G P P++ W++ N + ++
Sbjct: 3612 LEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIH 3671
Query: 424 DDNQNLTLL--EVTRDDDAIYHCRAENDGG--MIEASAVLTLEQVEI--IPPRIVLKPED 477
+ N + T + + R+D +Y C+AEN G A ++ LE ++ P + PE
Sbjct: 3672 NPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEA 3731
Query: 478 MDAFKETSVQMP 489
+ F +T ++ P
Sbjct: 3732 PEDFPQTPLKGP 3743
Score = 53.2 bits (122), Expect = 6e-06
Identities = 29/106 (27%), Positives = 51/106 (48%), Gaps = 3/106 (2%)
Query: 454 EASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD 513
E + V ++ + PP +V +++ + SV + C I P ++ W ++ +I
Sbjct: 928 ETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSI 987
Query: 514 RISITV---IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
IT I L+IR D+GR+ CSA N+ G + S +L V+
Sbjct: 988 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 53.2 bits (122), Expect = 6e-06
Identities = 52/216 (24%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGT-- 236
+P F +P + G+ A F G P PE W D + I +N+ +++ ++GT
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQI-VNDYTHKVVIKEDGTQS 1514
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L++ A +D G + +A+N AG++ +I+ +A EH+ P+FV + + I
Sbjct: 1515 LIIVPATPSDSGEWTVVAQNRAGRS---SISVILTVEAVEHQ--VKPMFVE--KLKNVNI 1567
Query: 297 NETSVM-FDCTATGFPKPHVAWYFNGERMLLNERIILQHNG-----SILIKNVQNSDAGV 350
E S + ATG P P + W N + ++ ++ ++ G ++ I + + D+
Sbjct: 1568 KEGSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAW 1627
Query: 351 YTCQVENIHG------KISASVPLEVTAPPSFIVVP 380
YT N G K++ V P +++P
Sbjct: 1628 YTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIP 1663
Score = 52.8 bits (121), Expect = 8e-06
Identities = 33/94 (35%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 280 PAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNG--- 336
PA P F++ P + + SV+F C G PKPHV W +G + R + +N
Sbjct: 1079 PAAPYFITKPVVQ-KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTG 1137
Query: 337 --SILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
++I DAG YT V N HG+ SAS L
Sbjct: 1138 ECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 3/107 (2%)
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN--TVILPITG 418
++ A V + VT PP+ + N T I G++V C G P P++ WYR + I
Sbjct: 931 RVPAPVEIPVT-PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDF 989
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
+ L + E +D + C A N+ G + S L ++ E
Sbjct: 990 QITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSE 1036
Score = 50.8 bits (116), Expect = 3e-05
Identities = 31/117 (26%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 178 PCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--- 234
PC P F E + + G A+F GEPAP + W ++++ + Y I N
Sbjct: 3618 PCP-PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQL-CTSVYYTIIHNPNG 3675
Query: 235 -GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ 290
GT +V++ D GL+ C A+N+ G++ +++ + +P STP+
Sbjct: 3676 SGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKA--KSTPE 3730
Score = 50.4 bits (115), Expect = 4e-05
Identities = 70/313 (22%), Positives = 128/313 (40%), Gaps = 33/313 (10%)
Query: 274 AEEHKSPAPPVFVSTPQKRFAKINETSV------MFDCTATGFPKPHVAWYFNGERMLLN 327
A + KS A + + P + + + +V +F C + K +V WY NG +
Sbjct: 13734 AGQDKSVAELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSR-EKANVKWYRNGREIKEG 13792
Query: 328 ERIILQHNGSI---LIKNVQNSDAGVYTCQVENIHGK---ISASVPLEVTAPPSFIVVPT 381
++ + +GSI +IK+ + D Y C VE+ + +P+E+ PP I+
Sbjct: 13793 KKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAP 13852
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNT-VILPITGNLVLSDDN-QNLTLLEVTRDDD 439
G +V F + K ++W RN V++ + ++S+ L + ++ D
Sbjct: 13853 ------GADVVFLAEL-NKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ 13905
Query: 440 AIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPAS 499
Y A++ EA A L L P+I +D+ + M ++ P A
Sbjct: 13906 GEYRFIAKDK----EARAKLELAAA----PKIKTADQDLVVDVGKPLTMVVPYDAYPKAE 13957
Query: 500 IDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
+W K+ + + S I D GRY+ N +G+ A F+ +K
Sbjct: 13958 AEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK--AEGFINLKVID 14015
Query: 560 LPGDAYVNIALTQ 572
+PG N+ +T+
Sbjct: 14016 VPGPVR-NLEVTE 14027
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN 335
+ K P V P+ ET+ F C TG+P+P V WY NG+ + ++R ++++
Sbjct: 1834 DQKEKQKPDIVLYPEPVRVLEGETA-RFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD 1892
Query: 336 G--SILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF 376
G + I + ++ D G EN G I V LE+ F
Sbjct: 1893 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF 1935
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 291 KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER----IILQHNGSILIKNVQNS 346
K + + V F C +G+P P +AWY +G+R+ ER + S+ I V
Sbjct: 1298 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1357
Query: 347 DAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
D G+YT NI G S L V P + + PT
Sbjct: 1358 DEGIYTAFASNIKGNAICSGKLYV-EPAAPLGAPT 1391
Score = 47.6 bits (108), Expect = 3e-04
Identities = 32/135 (23%), Positives = 63/135 (46%), Gaps = 9/135 (6%)
Query: 430 TLLEVTRDDDAIYHCRAENDGGMIEASAV---LTLEQVEIIPP-RIVLKPEDMDAFKETS 485
T+ +T ++ ++ A N+ G + + + +EI P + ++ A ++
Sbjct: 26281 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 26340
Query: 486 VQMPCEIESVPPASIDWRKDGSRIVEDDRISIT---VIGSLIIRNVSVTDTGRYECSAFN 542
+ +P + P A+++WRKDG + E R++++ + SL I+ S D G YE N
Sbjct: 26341 IDVP--FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 26398
Query: 543 DYGRDTASVFLTVKD 557
G T + + V D
Sbjct: 26399 SAGSITVPITIIVLD 26413
Score = 46.8 bits (106), Expect = 5e-04
Identities = 56/208 (26%), Positives = 89/208 (42%), Gaps = 24/208 (11%)
Query: 305 CTAT-GFPKPHVA--WYFNGERMLLNER--IILQHN-GSILIKNVQNSDAGVYTCQVENI 358
CT T F P+V W+ NG + R ++H + I +V+ D G YTC+ E++
Sbjct: 9689 CTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL 9748
Query: 359 HGKISASV---PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
+ P++ T IVV +Q+A F C+ + WY+ L
Sbjct: 9749 ETSAELRIEAEPIQFTKRIQNIVVSEHQSAT------FECEV-SFDDAIVTWYKGPTELT 9801
Query: 416 ITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAE-NDGGMIEASAVLTLEQVEIIPPRIV 472
+ +D + +T+ VT DD+ +Y A G ++A L L EI ++
Sbjct: 9802 ESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEI---KLE 9858
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASI 500
LKP D+ + MP I +VPP I
Sbjct: 9859 LKPPDIPDSRVPIPTMP--IRAVPPEEI 9884
Score = 46.0 bits (104), Expect = 0.001
Identities = 67/275 (24%), Positives = 114/275 (41%), Gaps = 27/275 (9%)
Query: 308 TGFPKPHVAWYFNGERMLLNERII--LQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
+G P P V W N ER L E I + S++IKN Q S GVY+ +N G+ +
Sbjct: 17476 SGKPPPTVTWNMN-ERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKT 17534
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDN---VWFTCKAK-GTPKPSIKWYRNTVILPITGNLV 421
+ ++V P + P + ++ WF+ + G+P + + +
Sbjct: 17535 IIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVT 17594
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGM---IEASAVLTLEQVEIIPPRIVLKPEDM 478
+ QN T+ + + + AEN GM +E S L + + +P R PED+
Sbjct: 17595 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPER----PEDL 17650
Query: 479 DAFKET--SVQMPCEIESVPPAS--IDWRKDGSRIVEDDRISITVIGSLIIRNVSVT--- 531
+ + T +V + S I++ + SR++ ++ +L+ R +V
Sbjct: 17651 EVKEVTKNTVTLTWNPPKYDGGSEIINYVLE-SRLIGTEKFHKVTNDNLLSRKYTVKGLK 17709
Query: 532 --DTGRYECSAFNDYGRDTASVF---LTVKDNLLP 561
DT Y SA N G+ S +T KD L P
Sbjct: 17710 EGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAP 17744
Score = 45.2 bits (102), Expect = 0.002
Identities = 27/107 (25%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 454 EASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD 513
EA V ++ +++PP+I++ PE + +++ + P + W+K +V
Sbjct: 19813 EAEGVYEAKE-QLLPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSS 19870
Query: 514 RISITVIGS---LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+++ S LII++V+ D+G Y +A N G DT + + V D
Sbjct: 19871 HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMD 19917
Score = 44.8 bits (101), Expect = 0.002
Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 13/136 (9%)
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ +T+ ++ ++ A N+ G + ++ V I+ +V++P+ AF SVQ+
Sbjct: 24117 ITNLTQGEEYLFRVVAVNEKGRSDPRSLA----VPIVAKDLVIEPDVKPAFSSYSVQVGQ 24172
Query: 491 EIESVPPAS------IDWRKDGSRIVEDDRISIT---VIGSLIIRNVSVTDTGRYECSAF 541
+++ P S I W KDG + + RI++T + +L I+ D G+Y +
Sbjct: 24173 DLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVA 24232
Query: 542 NDYGRDTASVFLTVKD 557
N G+ TAS+ + D
Sbjct: 24233 NVVGQKTASIEIVTLD 24248
Score = 44.4 bits (100), Expect = 0.003
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 6/120 (5%)
Query: 262 HSKPAKMI--VRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYF 319
H + AK+ R A PP VS K I SV +C +G+P P V WY
Sbjct: 920 HGREAKVTETARVPAPVEIPVTPPTLVSG-LKNVTVIEGESVTLECHISGYPSPTVTWYR 978
Query: 320 NGERM--LLNERIILQHN-GSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSF 376
++ ++ +I Q ++I+ D+G +TC N G +S S L V F
Sbjct: 979 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEF 1038
Score = 44.4 bits (100), Expect = 0.003
Identities = 79/361 (21%), Positives = 147/361 (40%), Gaps = 50/361 (13%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILW-LRDSEVIPLNENRYEIFDNGT---LMVHEANEN 245
DV V G AV C + + W L D ++ P ++R + GT L+++ + +
Sbjct: 2453 DVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKP--DDRVQAIVKGTKQRLVINRTHAS 2510
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
D+G P K+IV R + + + +V+F+
Sbjct: 2511 DEG----------------PYKLIVGRVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEV 2554
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSIL---IKNVQNSDAGVYTCQV-ENI-HG 360
+ V W F + + + + ++ +G I + N+ D G YT ENI G
Sbjct: 2555 ELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYAGENITSG 2613
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
K++ + ++ P + V +Q A+ F C+ P +W R+ LP+T N+
Sbjct: 2614 KLTVAGGA-ISKPLTDQTVAESQEAV------FECEV-ANPDSKGEWLRDGKHLPLTNNI 2665
Query: 421 -VLSDDNQNLTLLEVTR-DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
SD ++ ++ T+ DD Y + + SA L +E V+I + LK ++
Sbjct: 2666 RSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKVEAVKI---KKTLK--NL 2716
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGR 535
+ E+ + W K+G + +++ +I+V G SL I+N ++ D
Sbjct: 2717 TVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESV 2776
Query: 536 Y 536
Y
Sbjct: 2777 Y 2777
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 6/130 (4%)
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
L+ A+N AG S P++++ A++ P + +S + I + +T
Sbjct: 14290 LYRVSAENKAGV--SDPSEILGPLTADD-AFVEPTMDLSAFKDGLEVIVPNPITILVPST 14346
Query: 309 GFPKPHVAWYFNGERMLLNERI---ILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
G+P+P W F + + +R+ L ++I + SD G+YT ++EN IS
Sbjct: 14347 GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGE 14406
Query: 366 VPLEVTAPPS 375
+ + V A PS
Sbjct: 14407 IDVNVIARPS 14416
Score = 44.4 bits (100), Expect = 0.003
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 6/129 (4%)
Query: 433 EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDAFKETS-VQMP 489
++T + + AEN+ G S + + + +++ P + LK P+ KE S ++
Sbjct: 20871 DLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLK 20930
Query: 490 CEIESVPPASIDWRKDGSRIVEDDRISI---TVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
I+ P S+ W+K + D R+S+ V +LI+ + +D G+Y + N G
Sbjct: 20931 IPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGT 20990
Query: 547 DTASVFLTV 555
++ + V
Sbjct: 20991 KEGTISIKV 20999
Score = 44.0 bits (99), Expect = 0.004
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%)
Query: 434 VTRDDDAIYHCRAENDGGMIEASAVL--TLEQVEIIPPRIVLKPEDMDAFKETSVQMPCE 491
V D + + RA N G+ E S + + + P I L+ D+ + + +P
Sbjct: 15277 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 15336
Query: 492 IESVPPASIDWRKDGSRIVEDDRISIT---VIGSLIIRNVSVTDTGRYECSAFNDYGRDT 548
+VP ++ W KDG + DR+++ + L + D G Y + N G T
Sbjct: 15337 FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSAT 15396
Query: 549 ASVFLTVKDNLLPG 562
AS+ VK LPG
Sbjct: 15397 ASI--NVKVIGLPG 15408
Score = 43.6 bits (98), Expect = 0.005
Identities = 48/228 (21%), Positives = 95/228 (41%), Gaps = 17/228 (7%)
Query: 317 WYFNGERMLLNERI-ILQHNG--SILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
WY N + N + I G ++ +K+V D G Y+ ++ K + + ++ P
Sbjct: 2299 WYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG--KKTTCKLKMK-PRP 2355
Query: 374 PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLE 433
+ + ++Q GD V K + + P ++ D ++ L+E
Sbjct: 2356 IAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIE 2415
Query: 434 -VTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEI 492
+T++D Y G + S +++ V++I P LK D++ + T + C++
Sbjct: 2416 DMTKEDAGNYSFTIPALG--LSTSGRVSVYSVDVITP---LK--DVNVIEGTKAVLECKV 2468
Query: 493 ESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYE 537
S+ W + +I DDR+ V G+ L+I +D G Y+
Sbjct: 2469 SVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYK 2516
Score = 42.7 bits (96), Expect = 0.008
Identities = 27/109 (24%), Positives = 44/109 (40%), Gaps = 1/109 (0%)
Query: 374 PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLL 432
P ++ P + G+ F C+ G P+P + WY N ++ + V D L ++
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIV 1900
Query: 433 EVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
+ D AEN G+IE L ++Q E + PE F
Sbjct: 1901 DCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEF 1949
Score = 42.7 bits (96), Expect = 0.008
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 282 PPVFVSTPQKRFAKINE-TSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSI 338
P + +S K + T+V D T G P P V+W +G + E ++ +Q N
Sbjct: 20220 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCT 20279
Query: 339 L-IKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPP 374
L + +V D+G YT EN G SA++ L+V P
Sbjct: 20280 LELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 20316
Score = 42.7 bits (96), Expect = 0.008
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 8/122 (6%)
Query: 365 SVPL---EVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG--N 419
SVP+ ++ PP+F ++ T + G+++ G P P++ W+++ V L T N
Sbjct: 23063 SVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVN 23122
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG-MIEASAVLTLEQVEIIPPRIVLKPEDM 478
+++N LT+ + R+D Y + N G IE V+ L++ PP +K +++
Sbjct: 23123 AESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMDEV 23180
Query: 479 DA 480
A
Sbjct: 23181 TA 23182
Score = 41.9 bits (94), Expect = 0.015
Identities = 49/229 (21%), Positives = 97/229 (42%), Gaps = 17/229 (7%)
Query: 263 SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFDCTATGFPKPHVAWYFNG 321
SKP++ +A + + AP +F+ + T + T TG P+P + W
Sbjct: 14597 SKPSRPTEEIQAVDTQE-APEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKAD 14655
Query: 322 ERMLLNERIILQH---NGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV---TAPPS 375
+ ++RI +++ ++ I + + SD G Y + N+ G+ +A V + V PP+
Sbjct: 14656 MILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPA 14715
Query: 376 F--IVVPTNQTAIIGDNVWFTCKAKGTPK-PSIKWYRNTVILPITGNLVLSDDNQNLTLL 432
I TN++ ++ W + G K + R + L + + N
Sbjct: 14716 AFDITDVTNESCLL---TWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT 14772
Query: 433 EVTRDDDAIYHCRAENDGGM---IEASAVLTLEQVEIIPPRIVLKPEDM 478
++ + + I+ AEN G+ ++AS + Q + P L+P D+
Sbjct: 14773 KLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 14821
Score = 41.9 bits (94), Expect = 0.015
Identities = 34/160 (21%), Positives = 68/160 (42%), Gaps = 6/160 (3%)
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+V E ++ F+ MA N AG++ + ++ ++ + E+ P + + AK
Sbjct: 21950 VVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK--EQTMLPELDLRGIYQKLVIAKAG 22007
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQN---SDAGVYTCQ 354
+ ++ + G PKP V W + + +R+ + + I N+ SD+G Y
Sbjct: 22008 D-NIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 22066
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFT 394
NI G++ + ++V P P + D V F+
Sbjct: 22067 ARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFS 22106
Score = 41.9 bits (94), Expect = 0.015
Identities = 33/108 (30%), Positives = 48/108 (44%), Gaps = 13/108 (12%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE-NRYEIFDNGT--- 236
QP + N + GE+ G P P I W++D E PL + R + + T
Sbjct: 25238 QPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGE--PLKQTTRVNVEETATSTV 25295
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
L + E N++D G + A N AG A ++ +IV K P PPV
Sbjct: 25296 LHIKEGNKDDFGKYTVTATNSAGTA-TENLSVIVLEK------PGPPV 25336
Score = 41.9 bits (94), Expect = 0.015
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN---GSILIKNVQNSDAGVYTCQV 355
TSV +G P P + WY + + + N + +++ SILIK+ ++G Y ++
Sbjct: 27815 TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKL 27874
Query: 356 ENIHGKISASVPLEVTAPP 374
N G SA++ +++ P
Sbjct: 27875 RNAMGSASATIRVQILDKP 27893
Score = 41.1 bits (92), Expect = 0.026
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 5/98 (5%)
Query: 372 APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQ---- 427
A P FI P Q + G +V F C+ G PKP + W ++ V L +S + Q
Sbjct: 1080 AAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGEC 1139
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
L + DD Y N G ASA L LE+ +
Sbjct: 1140 KLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEAD 1176
Score = 41.1 bits (92), Expect = 0.026
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 8/136 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT--L 237
Q+P P V V GE A F C TG P P++ W + ++I R+ + +G L
Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLI-RKSKRFRVRYDGIHYL 1897
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRK-----AEEHKSPAPPVFVSTPQKR 292
+ + D G + A+N G K I +R+ P P V P K
Sbjct: 1898 DIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKL 1957
Query: 293 FAKINETSVMFDCTAT 308
++ + D T T
Sbjct: 1958 QFEVQKVDRPVDTTET 1973
Score = 40.3 bits (90), Expect = 0.045
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 484 TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI---GSLIIRNVSVTDTGRYECSA 540
T +++P + P I W K + +D RI+I + ++ I + +DTG Y A
Sbjct: 14633 TKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEA 14692
Query: 541 FNDYGRDTASVFLTVKDNLLPGDAY 565
N GR TA V + V D P A+
Sbjct: 14693 VNVCGRATAVVEVNVLDKPGPPAAF 14717
Score = 39.9 bits (89), Expect = 0.060
Identities = 25/121 (20%), Positives = 50/121 (41%), Gaps = 3/121 (2%)
Query: 144 RMLENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTC 203
R+++ E+ + T + G A+ + + F+ + + G F C
Sbjct: 1253 RLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIKNYRILEGMGVTFHC 1312
Query: 204 VATGEPAPEILWLRDSEVIPLNEN-RYEIFDNG--TLMVHEANENDDGLFECMAKNVAGK 260
+G P P+I W +D + I E + + +G +L + D+G++ A N+ G
Sbjct: 1313 KMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGN 1372
Query: 261 A 261
A
Sbjct: 1373 A 1373
Score = 39.9 bits (89), Expect = 0.060
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 485 SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS-LIIRNVSVTDTGRYECSAFND 543
++++ I+ VP + W+K+ RI +T +GS L IRN + D G Y + N
Sbjct: 18162 TLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENP 18221
Query: 544 YGRDTASVFLTVKD 557
G T SV + V D
Sbjct: 18222 AGSKTVSVKVLVLD 18235
Score = 39.5 bits (88), Expect = 0.079
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 7/128 (5%)
Query: 250 FECMAKNVAGKAHSK--PAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
F +A N AG++ P ++V+ + E P + + +++ K+ +T +
Sbjct: 18114 FRVLAVNAAGESDPAHVPEPVLVKDRLEP---PELILDANMAREQHIKVGDT-LRLSAII 18169
Query: 308 TGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKISASV 366
G P P V W RI + GS L I+N + D G+Y+ VEN G + SV
Sbjct: 18170 KGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSV 18229
Query: 367 PLEVTAPP 374
+ V P
Sbjct: 18230 KVLVLDKP 18237
Score = 39.5 bits (88), Expect = 0.079
Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 309 GFPKPHVAWYFNGERMLLNERIILQH---NGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
G P P V+W + + + R+ ++ N ++++ + Q SDAG YT ++N+ G +
Sbjct: 20935 GKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGT 20994
Query: 366 VPLEVTAPPSFIVVP 380
+ ++V P P
Sbjct: 20995 ISIKVVGKPGIPTGP 21009
Score = 38.7 bits (86), Expect = 0.14
Identities = 65/324 (20%), Positives = 119/324 (36%), Gaps = 30/324 (9%)
Query: 164 VTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIP 223
+T TSL + P F ++P ++ G + VF C G P P + W + +P
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSG--VP 1121
Query: 224 LNEN-RYEIFDNGT-----LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEH 277
L RY++ N L++ +D G + + +N G+ S A ++ E
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGET-SASASLLEEADYELL 1180
Query: 278 KSPAPPVFVSTPQKRFA---KINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQ- 333
+ T F K+ ET+ F + + K + + + + ++++
Sbjct: 1181 MKSQQEMLYQTQVTAFVQEPKVGETAPGF--VYSEYEKEYEKEQALIRKKMAKDTVVVRT 1238
Query: 334 -------HNGSILIKNVQNSDAGVYTCQVENI-----HGKISASVPLEVTAPPSFIVVPT 381
H S + ++ + + +E + K++ + F +
Sbjct: 1239 YVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGFDLRIK 1298
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL---VLSDDNQNLTLLEVTRDD 438
N + G V F CK G P P I WY++ + L D +L + V +D
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 439 DAIYHCRAENDGGMIEASAVLTLE 462
+ IY A N G S L +E
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYVE 1382
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/67 (26%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Query: 311 PKPHVAWYFNGERMLLNERIILQHN---GSILIKNVQNSDAGVYTCQVENIHGKISASVP 367
P P V+W+ +G+ + ++R+ ++++ + + +DAG+YT +EN G +AS+
Sbjct: 15341 PVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASIN 15400
Query: 368 LEVTAPP 374
++V P
Sbjct: 15401 VKVIGLP 15407
Score = 38.7 bits (86), Expect = 0.14
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
++ + +E P+F ++ + +G ++ G PKP+I W ++ + L T +
Sbjct: 24149 VAKDLVIEPDVKPAF----SSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRIN 24204
Query: 422 LSD--DNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS-AVLTLEQVEIIPPRIVLKPEDM 478
++D D L++ E +DD Y N G AS ++TL++ + PP+ +K +D+
Sbjct: 24205 VTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPD--PPKGPVKFDDV 24262
Query: 479 DA 480
A
Sbjct: 24263 SA 24264
Score = 38.3 bits (85), Expect = 0.18
Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Query: 369 EVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL--SDDN 426
E PP I++P T G + G P P+ KW + + + +L + +D +
Sbjct: 19822 EQLLPPK-ILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSS 19880
Query: 427 QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
L + +VTR D Y AEN G + + + PP+ D+DA
Sbjct: 19881 SILIIKDVTRKDSGYYSLTAENSSG-TDTQKIKVVVMDAPGPPQPPFDISDIDA 19933
Score = 38.3 bits (85), Expect = 0.18
Identities = 36/156 (23%), Positives = 69/156 (44%), Gaps = 9/156 (5%)
Query: 427 QNLTLLEVTRDDDAIYHCRAENDGGMIEASAV--LTLEQVEIIPPRIVLKPEDMDAF--- 481
+ T+ ++ + + + A N G+ E + + + Q I PP I L +
Sbjct: 25988 KQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLR 26047
Query: 482 KETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV-IGSLIIRNVSVTDTGRYECSA 540
++++ I+ P + W K + + +I +T L+I NV+ D+GRY +
Sbjct: 26048 ASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTL 26107
Query: 541 FNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAMRD 576
N+ G TA V + V D+ A VN+ + + +D
Sbjct: 26108 ENNSGSKTAFVNVRVLDS---PSAPVNLTIREVKKD 26140
Score = 38.3 bits (85), Expect = 0.18
Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 2/74 (2%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIP--LNENRYEIFDNGTLMVHEANENDDGLF 250
+ GE+ + G P P + W +D I +N ++ + +L V +A + G++
Sbjct: 28897 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956
Query: 251 ECMAKNVAGKAHSK 264
AKN +G A ++
Sbjct: 28957 TVEAKNASGSAKAE 28970
Score = 38.3 bits (85), Expect = 0.18
Identities = 37/158 (23%), Positives = 62/158 (39%), Gaps = 5/158 (3%)
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
T V E + F AKN AG + + A V K E P + T Q K
Sbjct: 29529 TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIK-EPQIEPTADLTGITNQLITCK 29587
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIIL---QHNGSILIKNVQNSDAGVYT 352
+ D +G P P V W R+ +R+ + + ++ +K+ D+G Y
Sbjct: 29588 AGSPFTI-DVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYF 29646
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
+EN G + SV + V P + P +++ ++
Sbjct: 29647 LTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAES 29684
Score = 37.9 bits (84), Expect = 0.24
Identities = 42/171 (24%), Positives = 68/171 (39%), Gaps = 19/171 (11%)
Query: 246 DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE-TSVMFD 304
+ G +E K V SKP+ + + + PP S K F ++ E T+V
Sbjct: 17010 EGGEYEFRVKAVNAAGVSKPSATV--GPCDCQRPDMPP---SIDLKEFMEVEEGTNVNIV 17064
Query: 305 CTATGFPKPHVAWYF-------NGERMLLN---ERIILQHNGSILIKNVQNSDAGVYTCQ 354
G P P + W+ N E +L + ++++ +++I + SD G+YT
Sbjct: 17065 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTIT 17124
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNV---WFTCKAKGTPK 402
N G S + L V P V P ++ D + WF K G K
Sbjct: 17125 AVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSK 17175
Score = 37.9 bits (84), Expect = 0.24
Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 8/122 (6%)
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAF---KETSVQMPCEIESVPPASIDWRKDGSRIVED 512
S+ + + + E +PP + PE D S+++ ++ P + W KDG I +
Sbjct: 28870 SSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKR 28929
Query: 513 DRISIT-VIG--SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIA 569
+ IT V+G SL +R+ + G Y A N G A + + V+D PG I
Sbjct: 28930 MNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDT--PGKVVGPIR 28987
Query: 570 LT 571
T
Sbjct: 28988 FT 28989
Score = 37.5 bits (83), Expect = 0.32
Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 147 ENNEWMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVAT 206
++ EW VA +S++ H + +P F + +V + G AT
Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQV---KPMFVEKLKNVNIKEGSQLEMKVRAT 1580
Query: 207 GEPAPEILWLRDSEVI 222
G P P+I+WL++S++I
Sbjct: 1581 GNPNPDIVWLKNSDII 1596
Score = 36.7 bits (81), Expect = 0.56
Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 2/89 (2%)
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
+T +Q E P IVL PE + + + + C + P ++W +G I + R +
Sbjct: 1831 VTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVR 1890
Query: 519 VIG--SLIIRNVSVTDTGRYECSAFNDYG 545
G L I + DTG + +A N G
Sbjct: 1891 YDGIHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 36.7 bits (81), Expect = 0.56
Identities = 21/80 (26%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 384 TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD--NQNLTLLEVTRDDDAI 441
T +G + + KG P+P I W + +L + L D L + E R D
Sbjct: 18846 TVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGK 18905
Query: 442 YHCRAENDGGMIEASAVLTL 461
Y A+N G + SA++ +
Sbjct: 18906 YIISAKNSSGHAQGSAIVNV 18925
Score = 36.7 bits (81), Expect = 0.56
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 486 VQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECSAFN 542
VQ+ + PP ++ WRKD + D R SI S L I V+ DTG+Y + N
Sbjct: 28216 VQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIEN 28275
Query: 543 DYGRDTAS 550
G +S
Sbjct: 28276 GVGEPKSS 28283
Score = 36.3 bits (80), Expect = 0.74
Identities = 26/102 (25%), Positives = 40/102 (39%), Gaps = 6/102 (5%)
Query: 373 PPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNL 429
PP I+ + Q +GD + + KG P P + W + P + ++ L
Sbjct: 18142 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKL 18201
Query: 430 TLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPR 470
+ +D IY EN G S VL L++ PPR
Sbjct: 18202 EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG--PPR 18241
Score = 36.3 bits (80), Expect = 0.74
Identities = 26/87 (29%), Positives = 36/87 (41%), Gaps = 3/87 (3%)
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNG--SIL-IKNVQNSDAGVYTCQV 355
T+V F G P P W +G + +E ++ + S+L IKN D G Y V
Sbjct: 18453 TTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV 18512
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTN 382
N G + +V L V P P N
Sbjct: 18513 SNAAGSKTVAVHLTVLDVPGPPTGPIN 18539
Score = 36.3 bits (80), Expect = 0.74
Identities = 27/99 (27%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 465 EIIPPRIVLKP--EDMDAFKE-TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV-- 519
E +PPRI L + + K T+V + + P ++ W+KDG+ + + I + +
Sbjct: 20216 ENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQR 20275
Query: 520 -IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +L + +V+ D+G Y +A N G +A++ L V D
Sbjct: 20276 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD 20314
Score = 36.3 bits (80), Expect = 0.74
Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 13/146 (8%)
Query: 438 DDAIYHCR--AENDGGMIE-----ASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQMP 489
+DA Y R A+N G I + A+ + VE ++ +K +D K + ++
Sbjct: 22350 EDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLE 22409
Query: 490 CEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYGR 546
++ PP +++W KDG + ++ I + +L+ ++ + D+G Y +A N G
Sbjct: 22410 ADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG- 22468
Query: 547 DTASVFLTVKDNLLPGDAYVNIALTQ 572
A VK PG +A+T+
Sbjct: 22469 -FAKHIFNVKVLDRPGPPEGPLAVTE 22493
Score = 36.3 bits (80), Expect = 0.74
Identities = 46/160 (28%), Positives = 64/160 (40%), Gaps = 10/160 (6%)
Query: 239 VHEANENDDGLFECMAKNVAGKA-HSK-PAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
V + E + F A N AG H+ P +IV K E AP + + ++ I
Sbjct: 23827 VEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLE-----APDIDLDLELRKIINI 23881
Query: 297 NET-SVMFDCTATGFPKPHVAW-YFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQ 354
S+ G P P V W +GE + S+++ NV D+G YT
Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLT 23941
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFT 394
+EN G SA V + V PS V T I D+V T
Sbjct: 23942 LENSSGTKSAFVTVRVLDTPS-PPVNLKVTEITKDSVSIT 23980
Score = 35.9 bits (79), Expect = 0.97
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 2/78 (2%)
Query: 384 TAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPITG-NLVLSDDNQNLTLLEVTRDDDAI 441
T G NV G P P++ W ++ T++ P G + + + L L V R D
Sbjct: 20233 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGD 20292
Query: 442 YHCRAENDGGMIEASAVL 459
Y AEN G A+ L
Sbjct: 20293 YTITAENSSGSKSATIKL 20310
Score = 35.9 bits (79), Expect = 0.97
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 4/93 (4%)
Query: 485 SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITV-IGSLIIRNVSVTDTGRYECSAFND 543
S+++ I+ P + W K I + I +T SL++ NV+ D+G+Y + N
Sbjct: 23886 SLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENS 23945
Query: 544 YGRDTASVFLTVKDNLLPGDAYVNIALTQAMRD 576
G +A V + V D P VN+ +T+ +D
Sbjct: 23946 SGTKSAFVTVRVLDTPSPP---VNLKVTEITKD 23975
Score = 35.9 bits (79), Expect = 0.97
Identities = 39/150 (26%), Positives = 63/150 (42%), Gaps = 12/150 (8%)
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
V + EN + F A N G +PA + A+E P P + + ++ +
Sbjct: 25992 VTKLKENTEYNFRICAINSEGVG--EPATLPGSVVAQERIEP-PEIELDADLRKVVVLRA 26048
Query: 299 TSVM-FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGS---ILIKNVQNSDAGVYTCQ 354
++ + T G P+P V W +L +R ++ S ++I NV D+G Y
Sbjct: 26049 SATLRLFVTIKGRPEPEVKW--EKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLT 26106
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQT 384
+EN G +A V + V PS P N T
Sbjct: 26107 LENNSGSKTAFVNVRVLDSPS---APVNLT 26133
Score = 35.5 bits (78), Expect = 1.3
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 7/104 (6%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGT 236
+P + + V G++ +G P P I W +D +PL + N + D T
Sbjct: 24156 EPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTT 24213
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSP 280
L + E +++D G + NV G+ + +++ K + K P
Sbjct: 24214 LSIKETHKDDGGQYGITVANVVGQ-KTASIEIVTLDKPDPPKGP 24256
Score = 35.5 bits (78), Expect = 1.3
Identities = 23/84 (27%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 377 IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL--SDDNQNLTLLEV 434
+ + T+ A G++V KG P P++ W ++ L + +D + LT+ +V
Sbjct: 28202 VALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQV 28261
Query: 435 TRDDDAIYHCRAENDGGMIEASAV 458
TR+D Y EN G ++S V
Sbjct: 28262 TRNDTGKYILTIENGVGEPKSSTV 28285
Score = 35.5 bits (78), Expect = 1.3
Identities = 29/122 (23%), Positives = 53/122 (43%), Gaps = 8/122 (6%)
Query: 442 YHCRAENDGGMIE-----ASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVP 496
+ +A+ND G E +S ++ Q+E + + + + + I P
Sbjct: 29543 FRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRP 29602
Query: 497 PASIDWRKDGSRIVEDDRISITVI---GSLIIRNVSVTDTGRYECSAFNDYGRDTASVFL 553
+ W+ + R+ E DR+SIT +L +++ D+GRY + N G T SV +
Sbjct: 29603 APKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTV 29662
Query: 554 TV 555
V
Sbjct: 29663 VV 29664
Score = 35.1 bits (77), Expect = 1.7
Identities = 18/54 (33%), Positives = 25/54 (46%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGK 260
G PAPE+ W +D+ + N L++ E N D G F +N AGK
Sbjct: 21729 GRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGK 21782
Score = 35.1 bits (77), Expect = 1.7
Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 430 TLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE--IIPPRIVLKPEDMDAFKETSVQ 487
T+ +T + + A N G+ E + V + E ++PP I L D D K +++
Sbjct: 22744 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIEL---DADLRKVVTIR 22800
Query: 488 MPCE------IESVPPASIDWRKDGSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSA 540
C I+ P + W +D ++ I T +L I+ NV+ D+G+Y +
Sbjct: 22801 ACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTV 22860
Query: 541 FNDYGRDTASVFLTVKD 557
N G +A V + V D
Sbjct: 22861 ENSSGSKSAFVNVRVLD 22877
Score = 35.1 bits (77), Expect = 1.7
Identities = 19/77 (24%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Query: 484 TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI---TVIGSLIIRNVSVTDTGRYECSA 540
TSV++ I P +I+W KD + + + + T + S++I++ ++G YE
Sbjct: 27815 TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKL 27874
Query: 541 FNDYGRDTASVFLTVKD 557
N G +A++ + + D
Sbjct: 27875 RNAMGSASATIRVQILD 27891
Score = 34.7 bits (76), Expect = 2.2
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 1/89 (1%)
Query: 176 DLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF-DN 234
++P P + D S G+ A F C +G + +D ++ P R F D
Sbjct: 3339 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDT 3398
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHS 263
L + EA D+G + +A N G+ S
Sbjct: 3399 YQLEIAEAYPEDEGTYTFVASNAVGQVSS 3427
Score = 34.7 bits (76), Expect = 2.2
Identities = 27/83 (32%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 388 GDNVWFTCKAKGTPKPSIKWYRNTVILPITG--NLVLSDDNQNLTLLEVTRDDDAIYHCR 445
GDN+ G PKP++ W + IL T N + + L + E R D Y
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 22066
Query: 446 AENDGGMIEASAVLTLEQVEIIP 468
A N G E V+T+ QV IP
Sbjct: 22067 ARNIVG--EVGDVITI-QVHDIP 22086
Score = 34.7 bits (76), Expect = 2.2
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 3/72 (4%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEI---FDNGTLMVHEANENDD 247
+ V GE V G+P P+++W +D + + R EI TL+V + D
Sbjct: 25644 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 25703
Query: 248 GLFECMAKNVAG 259
G + NV G
Sbjct: 25704 GQYILKLSNVGG 25715
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/54 (31%), Positives = 26/54 (48%)
Query: 398 KGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGG 451
KG P+P +KW + IL + ++ L + VTR D Y+ EN+ G
Sbjct: 26059 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSG 26112
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/70 (24%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 388 GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSD--DNQNLTLLEVTRDDDAIYHCR 445
G+++ +G P P + W+++ V + N+ ++D + +L + + TRD +Y
Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE 28959
Query: 446 AENDGGMIEA 455
A+N G +A
Sbjct: 28960 AKNASGSAKA 28969
Score = 33.9 bits (74), Expect = 3.9
Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 4/85 (4%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN---GTLMVHEANENDD 247
+ V G+ G P P+I W ++ +V+ + E R ++ + L + EA D
Sbjct: 18845 ITVRVGQTIRILARVKGRPEPDITWTKEGKVL-VREKRVDLIQDLPRVELQIKEAVRADH 18903
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRR 272
G + AKN +G A ++ R
Sbjct: 18904 GKYIISAKNSSGHAQGSAIVNVLDR 18928
Score = 33.5 bits (73), Expect = 5.2
Identities = 31/149 (20%), Positives = 63/149 (42%), Gaps = 9/149 (6%)
Query: 229 YEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVST 288
Y + + +L+V E F A+N G + + A+ + +A+E P P + +
Sbjct: 19777 YSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVY--EAKEQLLP-PKILM-- 19831
Query: 289 PQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGS---ILIKNVQN 345
P++ K + + + G P P W + ++ + + + S ++IK+V
Sbjct: 19832 PEQITIKAGK-KLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTR 19890
Query: 346 SDAGVYTCQVENIHGKISASVPLEVTAPP 374
D+G Y+ EN G + + + V P
Sbjct: 19891 KDSGYYSLTAENSSGTDTQKIKVVVMDAP 19919
Score = 33.5 bits (73), Expect = 5.2
Identities = 22/86 (25%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Query: 309 GFPKPHVAWYFNGERMLLNERIIL---QHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
G PKP ++W +G + +E + ++ ++ IKN + G YT ++N +I+
Sbjct: 28516 GKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVP 28575
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNV 391
+ + PPS P I D+V
Sbjct: 28576 ITVITLGPPSKPKGPIRFDEIKADSV 28601
Score = 33.1 bits (72), Expect = 6.9
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 12/108 (11%)
Query: 462 EQVEIIPPRIVLKPE--DMDAF--KETSVQMPCEIESV------PPASIDWRKDG-SRIV 510
E E I P+ +L+P D+DA K V+ C I P + WRK G +V
Sbjct: 19517 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 19576
Query: 511 EDDRISIT-VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
++ + + L+I N + D+G+Y + N G V + V D
Sbjct: 19577 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLD 19624
Score = 33.1 bits (72), Expect = 6.9
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 153 HVAATCYQPASVTGTSLAAMKHHDLP--CQQPQFESEPNDVEVSFGENAVFTCVATGEPA 210
+ A +P+ TG ++ A D P P+++ + + V GE+ G+P
Sbjct: 23444 NAAGVFSEPSESTG-AITARDEVDPPRISMDPKYK---DTIVVHAGESFKVDADIYGKPI 23499
Query: 211 PEILWLRDSEVIPLNENRYEIFDNG---TLMVHEANENDDGLFECMAKNVAGK 260
P I W++ + + N R EI +L V +A D G + AKNVAG+
Sbjct: 23500 PTIQWIKGDQELS-NTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGE 23551
Score = 33.1 bits (72), Expect = 6.9
Identities = 28/140 (20%), Positives = 58/140 (41%), Gaps = 8/140 (5%)
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
++ + ++ LF +A N G++ + + + K + P F S ++
Sbjct: 24116 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYS----VQVG 24171
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN---GSILIKNVQNSDAGVYTCQ 354
+ + + +G PKP + W +G + RI + + ++ IK D G Y
Sbjct: 24172 Q-DLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 24230
Query: 355 VENIHGKISASVPLEVTAPP 374
V N+ G+ +AS+ + P
Sbjct: 24231 VANVVGQKTASIEIVTLDKP 24250
Score = 33.1 bits (72), Expect = 6.9
Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 10/112 (8%)
Query: 153 HVAATCYQPASVTGTSLAAMKHHDLP--CQQPQFESEPNDVEVSFGENAVFTCVATGEPA 210
+ A +P+ TG + A +LP P+F + + V+ GE G+P
Sbjct: 24526 NAAGAISKPSDSTGP-ITAKDEVELPRISMDPKFR---DTIVVNAGETFRLEADVHGKPL 24581
Query: 211 PEILWLRDSEVIPLNENRYEIFD---NGTLMVHEANENDDGLFECMAKNVAG 259
P I WLR + I R EI + L+V +A D G + A NVAG
Sbjct: 24582 PTIEWLRGDKEIE-ESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 24632
Score = 33.1 bits (72), Expect = 6.9
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 9/134 (6%)
Query: 433 EVTRDDDAIYHCRAENDGGMIEASAVLT---LEQVEIIPPRIVL--KPEDMDAFKETSV- 486
E+T D + A N + + T + + ++ PPR+++ K D+ K V
Sbjct: 26675 ELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVL 26734
Query: 487 QMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS---LIIRNVSVTDTGRYECSAFND 543
++ +I P I W KDG I E R I + L +++ DTG+Y + N
Sbjct: 26735 KINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNV 26794
Query: 544 YGRDTASVFLTVKD 557
G + +V V D
Sbjct: 26795 AGTRSVAVNCKVLD 26808
Score = 32.7 bits (71), Expect = 9.1
Identities = 26/107 (24%), Positives = 43/107 (40%), Gaps = 4/107 (3%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVAT--GEPAPEILWLRDSEVIPLNENRYEIFDNG-- 235
Q+P F+ + + + A F C T G+P + WL D + + I + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYC 1760
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAP 282
+L A D G+ C A N G H+ ++ K+ +S P
Sbjct: 1761 SLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLP 1807
Score = 32.7 bits (71), Expect = 9.1
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 13/138 (9%)
Query: 430 TLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEI--IPPRIVLKPEDMDAFKETSVQ 487
T+ ++ + + +A N G+ + SA + + +PP I LK E M+ + T+V
Sbjct: 17004 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVN 17062
Query: 488 MPCEIESVPPASIDWRKDGSR-------IVEDDRISITVIG---SLIIRNVSVTDTGRYE 537
+ +I+ VP ++ W K + ++ D ++ V+ +L+I +DTG Y
Sbjct: 17063 IVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYT 17122
Query: 538 CSAFNDYGRDTASVFLTV 555
+A N+ G + + L V
Sbjct: 17123 ITAVNNLGTASKEMRLNV 17140
Score = 32.7 bits (71), Expect = 9.1
Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 492 IESVPPASIDWRKDGSRIVEDDRISITVI-GSLIIRNVSVTDTGRYECSAFNDYGRDTAS 550
+ PP ++ W + + ++ I T I S++I+N + G Y A N+ G +
Sbjct: 17475 VSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKT 17534
Query: 551 VFLTVKDNLLPG 562
+ + V D +PG
Sbjct: 17535 IIVDVLD--VPG 17544
Score = 32.7 bits (71), Expect = 9.1
Identities = 36/133 (27%), Positives = 51/133 (38%), Gaps = 5/133 (3%)
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM- 302
EN + A N G +PA + KAE+ P P + + ++ I +
Sbjct: 22750 ENQEYKIRIYAMNSEGLG--EPALVPGTPKAEDRMLP-PEIELDADLRKVVTIRACCTLR 22806
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIK-NVQNSDAGVYTCQVENIHGK 361
G P P V W + L I + ++LI NV D+G Y VEN G
Sbjct: 22807 LFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGS 22866
Query: 362 ISASVPLEVTAPP 374
SA V + V P
Sbjct: 22867 KSAFVNVRVLDTP 22879
Score = 32.7 bits (71), Expect = 9.1
Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Query: 309 GFPKPHVAWYFNGERMLLNERIILQHNGS---ILIKNVQNSDAGVYTCQVENIHGKISAS 365
G P+P+++W +GE + R+ ++ + + IK D G YT N G + +
Sbjct: 25264 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATEN 25323
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNV 391
+ + V P V P + D V
Sbjct: 25324 LSVIVLEKPGPPVGPVRFDEVSADFV 25349
Score = 32.7 bits (71), Expect = 9.1
Identities = 32/137 (23%), Positives = 52/137 (37%), Gaps = 3/137 (2%)
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
V + ++ F A N AGK S ++ + +P + + Q +
Sbjct: 29242 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKA-VDRLTAPELDIDANFKQTHVVRAGA 29300
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVEN 357
+ +F G P P W + L I + S L ++N +DAG YT VEN
Sbjct: 29301 SIRLF-IAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVEN 29359
Query: 358 IHGKISASVPLEVTAPP 374
G S + ++V P
Sbjct: 29360 NSGSKSITFTVKVLDTP 29376
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 149 bits (361), Expect = 7e-35
Identities = 110/385 (28%), Positives = 180/385 (46%), Gaps = 35/385 (9%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT---LMVHEANENDD 247
VE+S GE+ FTC A GEP I W ++ R + G L ++ AN D
Sbjct: 30 VELSVGESKFFTCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDA 88
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
G++ C A + G+ + + +K + V +PQ+ F + + V+ C
Sbjct: 89 GIYRCQATDAKGQTQEATVVLEIYQKLTFRE-------VVSPQE-FKQGEDAEVV--CRV 138
Query: 308 TGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVE-NIHGKISA 364
+ P P V+W ++ E + + + R+ + N ++ I N+ SD G+Y C+ G+I
Sbjct: 139 SSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRVEARGEIDF 198
Query: 365 SVPLEVTAPPSFIVVPT---NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
+ + P I +P N TA G+ + F+C+A G+P+P+I W+RN ++ +
Sbjct: 199 RDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYI 258
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAF 481
L N LT+ + D Y CRA N G E A L QV + P I LK E +
Sbjct: 259 LKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFL---QVFVQPHIIQLKNE--TTY 313
Query: 482 KETSVQMPCEIESVPPASIDWRK--DGSRIVEDDRI---SITVIG-----SLIIRNVSVT 531
+ V + C+ E P I W++ DG E D+ I V G SL I++V ++
Sbjct: 314 ENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLS 373
Query: 532 DTGRYECSAFNDYGRDTASVFLTVK 556
+GRY+C A + G S++L ++
Sbjct: 374 GSGRYDCEAASRIGGHQKSMYLDIE 398
Score = 142 bits (344), Expect = 8e-33
Identities = 109/405 (26%), Positives = 178/405 (43%), Gaps = 36/405 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F + E GE+A C + PAP + WL + EV +++NR + N L
Sbjct: 113 QKLTFREVVSPQEFKQGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQ 172
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ N++D+G++ C + A G+ + +IV PP +S PQK F
Sbjct: 173 ILNINKSDEGIYRCEGRVEARGEIDFRDIIVIVN---------VPPA-ISMPQKSFNATA 222
Query: 298 ETS--VMFDCTATGFPKPHVAWYFNGERMLLNERIILQ-HNGSILIKNVQNSDAGVYTCQ 354
E + F C A+G P+P ++W+ NG+ + NE+ IL+ N + ++N+ NSD G Y C+
Sbjct: 223 ERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVCR 282
Query: 355 VENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
N G+ L+V P I + N+T V C A+G P P I W R
Sbjct: 283 ATNKAGEDEKQAFLQVFVQPHIIQLK-NETTYENGQVTLVCDAEGEPIPEITWKRAVDGF 341
Query: 415 PIT-------GNLVLSDDN--QNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
T G + + + +L + +V Y C A + G + S L +E
Sbjct: 342 TFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGRYDCEAASRIGGHQKSMYLDIEYA- 400
Query: 466 IIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS--- 522
P+ + +++ + + C+++S PPASI WR+D + + ++ +
Sbjct: 401 ---PKFISNQTIYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRK 457
Query: 523 --LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAY 565
L I S D GRY C+A N G L + D +P Y
Sbjct: 458 MILEIAPTSDNDFGRYNCTATNHIGTRFQEYILALAD--VPSSPY 500
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 147 bits (356), Expect = 3e-34
Identities = 90/289 (31%), Positives = 140/289 (48%), Gaps = 10/289 (3%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
FE +P EV G A F C + P I W + +P+ +R G L +++ +
Sbjct: 137 FEVQPISTEVHEGGVARFACKISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVS 196
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
+ D G + C+A VA + S A + V A+E KS P ++ PQ +++T V+
Sbjct: 197 QRDSGNYRCIAATVAHRRKSMEASLTV-IPAKESKSFHTPTIIAGPQNITTSLHQT-VVL 254
Query: 304 DCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQ--VENIH 359
+C ATG PKP ++W + + N R++ NG+++I +V+ AGVY C+
Sbjct: 255 ECMATGNPKPIISWSRLDHKSIDVFNTRVL--GNGNLMISDVRLQHAGVYVCRATTPGTR 312
Query: 360 GKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGN 419
A L V APPSF+ P + T F C+A+G P P + W +N + G
Sbjct: 313 NFTVAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGR 372
Query: 420 LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP 468
+ + N L + ++ +DDAIY C AEN G I + A LT+ E P
Sbjct: 373 IKMY--NSKLVINQIIPEDDAIYQCMAENSQGSILSRARLTVVMSEDRP 419
Score = 128 bits (310), Expect = 1e-28
Identities = 106/389 (27%), Positives = 166/389 (42%), Gaps = 34/389 (8%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F EP DV V+ + V C A GE ++ WL++ + N+ R E+ NG+L + E
Sbjct: 41 FVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENK-RIEVLSNGSLYISEVE 99
Query: 244 -----ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
++D+G ++C+A N G S+ A + + + P +ST +++E
Sbjct: 100 GRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQP-----IST------EVHE 148
Query: 299 TSVM-FDCTATGFPKPHVAWYFNGERMLLN-ERIILQHNGSILIKNVQNSDAGVYTCQVE 356
V F C + P + W FN + + +RI G + I +V D+G Y C
Sbjct: 149 GGVARFACKISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAA 208
Query: 357 NI-HGKISASVPLEVTAP--------PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
+ H + S L V P+ I P N T + V C A G PKP I W
Sbjct: 209 TVAHRRKSMEASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISW 268
Query: 408 YR-NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEI 466
R + + + VL N NL + +V +Y CRA G A+ TL +
Sbjct: 269 SRLDHKSIDVFNTRVLG--NGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATL--TVL 324
Query: 467 IPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIR 526
PP V PE + + + + C+ E +P + W K+G +I + RI + L+I
Sbjct: 325 APPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKM-YNSKLVIN 383
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ D Y+C A N G + LTV
Sbjct: 384 QIIPEDDAIYQCMAENSQGSILSRARLTV 412
Score = 79.0 bits (186), Expect = 1e-13
Identities = 54/190 (28%), Positives = 82/190 (43%), Gaps = 13/190 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLMVH 240
P + P ++ S + V C+ATG P P I W R D + I + R + NG LM+
Sbjct: 235 PTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTR--VLGNGNLMIS 292
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ G++ C A G + A + APP FV P+ + +
Sbjct: 293 DVRLQHAGVYVCRA-TTPGTRNFTVAMATL-------TVLAPPSFVEWPES-LTRPRAGT 343
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
F C A G P P ++W NG ++ N RI + +N ++I + D +Y C EN G
Sbjct: 344 ARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKM-YNSKLVINQIIPEDDAIYQCMAENSQG 402
Query: 361 KISASVPLEV 370
I + L V
Sbjct: 403 SILSRARLTV 412
Score = 58.4 bits (135), Expect = 2e-07
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 10/172 (5%)
Query: 375 SFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL-VLSDDNQNLTLLE 433
SF+ P + T D V C+A G + W +N + + VLS+ + ++ +E
Sbjct: 40 SFVKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVE 99
Query: 434 VTR---DDDAIYHCRAEND-GGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
R D+ Y C A N G ++ A L L + ++P + + +
Sbjct: 100 GRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFE----VQPISTEVHEGGVARFA 155
Query: 490 CEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVSVTDTGRYECSA 540
C+I S PPA I W + + + + DRI+ G L I +VS D+G Y C A
Sbjct: 156 CKISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIA 207
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 144 bits (349), Expect = 2e-33
Identities = 90/288 (31%), Positives = 140/288 (48%), Gaps = 7/288 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F P G A F C G P P I W ++ I + RY + G L +
Sbjct: 141 FHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLR 200
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE-EHKSPAPPVFVSTPQKRFAKINETSVM 302
D G+F C+A N+A S A++ V +K PA + V P+ +++T+V+
Sbjct: 201 AEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPA--ILVG-PENLTLTVHQTAVL 257
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
+C ATG P+P V+W R + E I + G+++I +V +GVY C ++
Sbjct: 258 -ECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRV 316
Query: 363 --SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
+A L V AP F+ P + + G FTC+A+G P P + W +N +L G++
Sbjct: 317 RRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHV 376
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP 468
L ++N LT+ + +D+AIY C AEN G +ASA LT+ E +P
Sbjct: 377 RLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLP 424
Score = 118 bits (285), Expect = 1e-25
Identities = 102/389 (26%), Positives = 155/389 (39%), Gaps = 32/389 (8%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE-- 241
F EP+D G+ V C G P I W ++ +P + NG+LM+
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELP-ESTHSTLLANGSLMIRHFR 102
Query: 242 ----ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D+G +EC+A+N G S+ A++ ++ H P V RF
Sbjct: 103 LEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARF---- 158
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLL-NERIILQHNGSILIKNVQNSDAGVYTCQVE 356
C G PKP + W N + NER L G + I ++ D G++ C
Sbjct: 159 ------QCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVAS 212
Query: 357 NIHG-KISASVPLEVTAP-------PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWY 408
NI +IS L V+ P+ +V P N T + C A G P+P + W
Sbjct: 213 NIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWS 272
Query: 409 R-NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
R + + + G VL N L + +VT +Y C A G + +A L V
Sbjct: 273 RLDGRPIGVEGIQVLGTGN--LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRL--VVQA 328
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS-LIIR 526
P V P+ + T+ C+ + PP + W K+G + + + S L I
Sbjct: 329 PAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTIS 388
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ D Y+C A N G AS LTV
Sbjct: 389 GIGPEDEAIYQCVAENSAGSSQASARLTV 417
Score = 87.0 bits (206), Expect = 4e-16
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 11/208 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P P ++ ++ + AV CVATG P P + W R + P+ ++ G L++
Sbjct: 236 KEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSR-LDGRPIGVEGIQVLGTGNLII 294
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ G++ C A ++P + R AP FV PQ ++ T
Sbjct: 295 SDVTVQHSGVYVCAA--------NRPGTRVRRTAQGRLVVQAPAEFVQHPQS-ISRPAGT 345
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENI 358
+ MF C A G P PHV W NG+ + + L++N S L I + D +Y C EN
Sbjct: 346 TAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENS 405
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAI 386
G AS L V P N A+
Sbjct: 406 AGSSQASARLTVLWAEGLPGPPRNVRAV 433
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 162 ASVTGTSLAAMKHHDLPCQQP-QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSE 220
A+ GT + L Q P +F P + G A+FTC A GEP P + WL++ +
Sbjct: 309 ANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ 368
Query: 221 VIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHS 263
V+ + +N TL + D+ +++C+A+N AG + +
Sbjct: 369 VLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQA 411
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/178 (23%), Positives = 80/178 (44%), Gaps = 9/178 (5%)
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP-ITGNLVLSDDNQNL 429
+A +F V P++ A+ G + C+ +GTP I W +N V LP T + +L++ + +
Sbjct: 39 SAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMI 98
Query: 430 TLLEV----TRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+ + D+ Y C A+N G++ S ++ + + P+ +
Sbjct: 99 RHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRKARIQAATMSDFHV--HPQATVGEEGGV 155
Query: 486 VQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVSVTDTGRYECSAFN 542
+ C+I +P I W K+ I +++R ++ G L I + D G + C A N
Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASN 213
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 144 bits (349), Expect = 2e-33
Identities = 90/288 (31%), Positives = 140/288 (48%), Gaps = 7/288 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F P G A F C G P P I W ++ I + RY + G L +
Sbjct: 141 FHVHPQATVGEEGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLR 200
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE-EHKSPAPPVFVSTPQKRFAKINETSVM 302
D G+F C+A N+A S A++ V +K PA + V P+ +++T+V+
Sbjct: 201 AEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPA--ILVG-PENLTLTVHQTAVL 257
Query: 303 FDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
+C ATG P+P V+W R + E I + G+++I +V +GVY C ++
Sbjct: 258 -ECVATGNPRPIVSWSRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRV 316
Query: 363 --SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
+A L V AP F+ P + + G FTC+A+G P P + W +N +L G++
Sbjct: 317 RRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHV 376
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIP 468
L ++N LT+ + +D+AIY C AEN G +ASA LT+ E +P
Sbjct: 377 RLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLP 424
Score = 118 bits (285), Expect = 1e-25
Identities = 102/389 (26%), Positives = 155/389 (39%), Gaps = 32/389 (8%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE-- 241
F EP+D G+ V C G P I W ++ +P + NG+LM+
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELP-ESTHSTLLANGSLMIRHFR 102
Query: 242 ----ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D+G +EC+A+N G S+ A++ ++ H P V RF
Sbjct: 103 LEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARF---- 158
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLL-NERIILQHNGSILIKNVQNSDAGVYTCQVE 356
C G PKP + W N + NER L G + I ++ D G++ C
Sbjct: 159 ------QCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVAS 212
Query: 357 NIHG-KISASVPLEVTAP-------PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWY 408
NI +IS L V+ P+ +V P N T + C A G P+P + W
Sbjct: 213 NIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWS 272
Query: 409 R-NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
R + + + G VL N L + +VT +Y C A G + +A L V
Sbjct: 273 RLDGRPIGVEGIQVLGTGN--LIISDVTVQHSGVYVCAANRPGTRVRRTAQGRL--VVQA 328
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS-LIIR 526
P V P+ + T+ C+ + PP + W K+G + + + S L I
Sbjct: 329 PAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTIS 388
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ D Y+C A N G AS LTV
Sbjct: 389 GIGPEDEAIYQCVAENSAGSSQASARLTV 417
Score = 87.0 bits (206), Expect = 4e-16
Identities = 58/208 (27%), Positives = 89/208 (42%), Gaps = 11/208 (5%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
++P P ++ ++ + AV CVATG P P + W R + P+ ++ G L++
Sbjct: 236 KEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSR-LDGRPIGVEGIQVLGTGNLII 294
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ G++ C A ++P + R AP FV PQ ++ T
Sbjct: 295 SDVTVQHSGVYVCAA--------NRPGTRVRRTAQGRLVVQAPAEFVQHPQS-ISRPAGT 345
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENI 358
+ MF C A G P PHV W NG+ + + L++N S L I + D +Y C EN
Sbjct: 346 TAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENS 405
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAI 386
G AS L V P N A+
Sbjct: 406 AGSSQASARLTVLWAEGLPGPPRNVRAV 433
Score = 59.3 bits (137), Expect = 9e-08
Identities = 30/103 (29%), Positives = 51/103 (49%), Gaps = 1/103 (0%)
Query: 162 ASVTGTSLAAMKHHDLPCQQP-QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSE 220
A+ GT + L Q P +F P + G A+FTC A GEP P + WL++ +
Sbjct: 309 ANRPGTRVRRTAQGRLVVQAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ 368
Query: 221 VIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHS 263
V+ + +N TL + D+ +++C+A+N AG + +
Sbjct: 369 VLGPGGHVRLKNNNSTLTISGIGPEDEAIYQCVAENSAGSSQA 411
Score = 53.6 bits (123), Expect = 5e-06
Identities = 42/178 (23%), Positives = 80/178 (44%), Gaps = 9/178 (5%)
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP-ITGNLVLSDDNQNL 429
+A +F V P++ A+ G + C+ +GTP I W +N V LP T + +L++ + +
Sbjct: 39 SAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMI 98
Query: 430 TLLEV----TRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+ + D+ Y C A+N G++ S ++ + + P+ +
Sbjct: 99 RHFRLEPGGSPSDEGDYECVAQNRFGLV-VSRKARIQAATMSDFHV--HPQATVGEEGGV 155
Query: 486 VQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNVSVTDTGRYECSAFN 542
+ C+I +P I W K+ I +++R ++ G L I + D G + C A N
Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASN 213
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 144 bits (348), Expect = 2e-33
Identities = 106/373 (28%), Positives = 175/373 (46%), Gaps = 36/373 (9%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+P+ E + P + + G C A G P P+I W R S+ +P + +G L +
Sbjct: 118 EPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRR-SDGLPFSSKIKLRKFSGVLEI 176
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G +EC+A+N GK + R + + A P +V + + E
Sbjct: 177 PNFQQEDAGSYECIAENSRGKN-------VARGRLTYY---AKPHWVQLIKDVEIAV-ED 225
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
S+ ++C A+G PKP W NG ++L ER ++ NG++ I N+ +D+G++ C EN H
Sbjct: 226 SLYWECRASGKPKPSYRWLKNGAALVLEERTQIE-NGALTISNLSVTDSGMFQCIAENKH 284
Query: 360 GKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
G + +S L+V A P F P + + G V CK + +P+ W + V +
Sbjct: 285 GLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQE 344
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
+ L +D L + VT+ D Y C AEN G + L + + P RI L P
Sbjct: 345 HERISLLNDG-GLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTE----PTRITLAPS 399
Query: 477 DMDAFKETSVQMPCEIESVPPASI-----------DWRKDGSRIVEDDRISITVIGSLII 525
+MD SV +PC+++ P I D++KDGS +++ + G L+I
Sbjct: 400 NMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHF---EKVGGSSSGDLMI 456
Query: 526 RNVSVTDTGRYEC 538
RN+ + +G+Y C
Sbjct: 457 RNIQLKHSGKYVC 469
Score = 127 bits (306), Expect = 3e-28
Identities = 95/374 (25%), Positives = 165/374 (44%), Gaps = 14/374 (3%)
Query: 191 VEVSFGENAVFTCVA---TGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDD 247
V V G+ V C +GE + ++ + + R+ + G L + + +D
Sbjct: 24 VSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV 83
Query: 248 GLFECMAKNVAGKAH--SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDC 305
G + C+ ++ A P +++R + P + V P+ A T V +C
Sbjct: 84 GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYE-PKIEVQFPETLPAAKGST-VKLEC 141
Query: 306 TATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
A G P P + W + ++ + + +G + I N Q DAG Y C EN GK A
Sbjct: 142 FALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVAR 201
Query: 366 VPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
L A P ++ + + + D++++ C+A G PKPS +W +N L + + +
Sbjct: 202 GRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQI--E 259
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKE 483
N LT+ ++ D ++ C AEN G++ +SA L +V P P + +
Sbjct: 260 NGALTISNLSVTDSGMFQCIAENKHGLVYSSAEL---KVVASAPDFSKNPMKKLVQVQVG 316
Query: 484 TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFND 543
+ V + C+ + P A W+K + E +RIS+ G L I NV+ D G Y C A N
Sbjct: 317 SLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQ 376
Query: 544 YGRDTASVFLTVKD 557
+G+ + L V +
Sbjct: 377 FGKANGTTHLVVTE 390
Score = 53.6 bits (123), Expect = 5e-06
Identities = 47/203 (23%), Positives = 75/203 (36%), Gaps = 22/203 (10%)
Query: 182 PQFESEPND--VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P F P V+V G C P W + +V R + ++G L +
Sbjct: 300 PDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW-KKGDVSVQEHERISLLNDGGLKI 358
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ D G + CMA+N GKA+ ++ P P + E
Sbjct: 359 ANVTKADAGTYTCMAENQFGKANGTTHLVVTE----------PTRITLAPSNMDVSVGE- 407
Query: 300 SVMFDCTATGFPKPHV--AWYFNGERMLLN------ERIILQHNGSILIKNVQNSDAGVY 351
SV+ C P + WYFNG E++ +G ++I+N+Q +G Y
Sbjct: 408 SVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKY 467
Query: 352 TCQVENIHGKISASVPLEVTAPP 374
C V+ +S++ L V P
Sbjct: 468 VCMVQTGVDSVSSAADLIVRGSP 490
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 143 bits (347), Expect = 3e-33
Identities = 111/399 (27%), Positives = 185/399 (46%), Gaps = 23/399 (5%)
Query: 183 QFESEPND-VEVSFGENAVFTCVATGE-PAPEILWLRDS--EVIPLNENRYEIFDNGTLM 238
+F E D V+ G + C P WL + IP + + G L
Sbjct: 134 EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLY 193
Query: 239 VHEANENDDGLFECMA-KNVAGKAHSKPAKMI-VRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N +D G + C+A ++ S +K + AE+ + AP + P + +A +
Sbjct: 194 IARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALV 253
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ V +C A G P P + W + L + + ++ I +V D G Y C+ E
Sbjct: 254 GQ-QVTLECFAFGNPVPRIKWR-KVDGSLSPQWTTAEP--TLQIPSVSFEDEGTYECEAE 309
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ + + V A P ++ V ++ A IG N+ + C A G P+P+++W RN L
Sbjct: 310 NSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS 369
Query: 417 TGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ VL+ D L +++ +D +Y C AEN G I ASA L V+ + P L P
Sbjct: 370 QNRVEVLAGD---LRFSKLSLEDSGMYQCVAENKHGTIYASAELA---VQALAPDFRLNP 423
Query: 476 ED--MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDT 533
+ A + + +PC+ + P A + W K +V R+++T G+LIIRN+S +D
Sbjct: 424 VRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDE 483
Query: 534 GRYECSAFNDYGRDTASVFLTVKD----NLLPGDAYVNI 568
G+Y C A N G+ ++ L+V+D L P A +N+
Sbjct: 484 GKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINL 522
Score = 112 bits (270), Expect = 7e-24
Identities = 95/366 (25%), Positives = 152/366 (41%), Gaps = 35/366 (9%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLMVHEANEND 246
P + G+ C A G P P I W + D + P TL + + D
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTA-----EPTLQIPSVSFED 300
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
+G +EC A+N G+ + ++IV+ A P ++ A I +++ + C
Sbjct: 301 EGTYECEAENSKGR-DTVQGRIIVQ---------AQPEWLKVISDTEADIG-SNLRWGCA 349
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
A G P+P V W NGE + R+ + G + + D+G+Y C EN HG I AS
Sbjct: 350 AAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGTIYASA 408
Query: 367 PLEVTA-PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
L V A P F + P + A G + C+ + PK + W + T IL + + ++
Sbjct: 409 ELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT 468
Query: 424 DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
D L + ++R D+ Y C AEN G ++ +L++ +I L P D
Sbjct: 469 PDG-TLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDAT----KITLAPSSADINLG 523
Query: 484 TSVQMPCEIESVPPASID--WRKDGSRIVEDD------RISIT-VIGSLIIRNVSVTDTG 534
++ + C P + W D I D R ++ IG L I N + G
Sbjct: 524 DNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGG 583
Query: 535 RYECSA 540
+Y C A
Sbjct: 584 KYTCMA 589
Score = 105 bits (252), Expect = 1e-21
Identities = 63/221 (28%), Positives = 109/221 (49%), Gaps = 10/221 (4%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP++ +D E G N + C A G+P P + WLR+ E + ++NR E+ G L
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLA-SQNRVEVLA-GDLRFS 383
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ + D G+++C+A+N G ++ A++ V+ A + + PV P R +I
Sbjct: 384 KLSLEDSGMYQCVAENKHGTIYAS-AELAVQALAPDFR--LNPVRRLIPAARGGEI---- 436
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ C PK V W E ++ + R+ + +G+++I+N+ SD G YTC EN G
Sbjct: 437 -LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
K +++ L V + P++ +GDN+ C A P
Sbjct: 496 KANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDP 536
Score = 61.3 bits (142), Expect = 2e-08
Identities = 77/284 (27%), Positives = 97/284 (34%), Gaps = 22/284 (7%)
Query: 283 PVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSI 338
PVF P + E V+ C A P W NG M L R L +
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 339 LIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQT-AIIGDNVWFTCK 396
++ + DAGVY C N G +S L F + A G V C
Sbjct: 97 IMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCN 156
Query: 397 AKG-TPKPSIKWYRNTV--ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
P S +W N +P G +S NL + D Y C A +
Sbjct: 157 PPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFS 216
Query: 454 EASAV-------LTLEQVEIIPPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK- 504
S L E + P I + P + A V + C P I WRK
Sbjct: 217 TKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKV 276
Query: 505 DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDT 548
DGS + T +L I +VS D G YEC A N GRDT
Sbjct: 277 DGSLSPQ----WTTAEPTLQIPSVSFEDEGTYECEAENSKGRDT 316
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 143 bits (347), Expect = 3e-33
Identities = 111/399 (27%), Positives = 185/399 (46%), Gaps = 23/399 (5%)
Query: 183 QFESEPND-VEVSFGENAVFTCVATGE-PAPEILWLRDS--EVIPLNENRYEIFDNGTLM 238
+F E D V+ G + C P WL + IP + + G L
Sbjct: 134 EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLY 193
Query: 239 VHEANENDDGLFECMA-KNVAGKAHSKPAKMI-VRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N +D G + C+A ++ S +K + AE+ + AP + P + +A +
Sbjct: 194 IARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALV 253
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ V +C A G P P + W + L + + ++ I +V D G Y C+ E
Sbjct: 254 GQ-QVTLECFAFGNPVPRIKWR-KVDGSLSPQWTTAEP--TLQIPSVSFEDEGTYECEAE 309
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ + + V A P ++ V ++ A IG N+ + C A G P+P+++W RN L
Sbjct: 310 NSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS 369
Query: 417 TGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ VL+ D L +++ +D +Y C AEN G I ASA L V+ + P L P
Sbjct: 370 QNRVEVLAGD---LRFSKLSLEDSGMYQCVAENKHGTIYASAELA---VQALAPDFRLNP 423
Query: 476 ED--MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDT 533
+ A + + +PC+ + P A + W K +V R+++T G+LIIRN+S +D
Sbjct: 424 VRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDE 483
Query: 534 GRYECSAFNDYGRDTASVFLTVKD----NLLPGDAYVNI 568
G+Y C A N G+ ++ L+V+D L P A +N+
Sbjct: 484 GKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINL 522
Score = 112 bits (270), Expect = 7e-24
Identities = 95/366 (25%), Positives = 152/366 (41%), Gaps = 35/366 (9%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLMVHEANEND 246
P + G+ C A G P P I W + D + P TL + + D
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTA-----EPTLQIPSVSFED 300
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
+G +EC A+N G+ + ++IV+ A P ++ A I +++ + C
Sbjct: 301 EGTYECEAENSKGR-DTVQGRIIVQ---------AQPEWLKVISDTEADIG-SNLRWGCA 349
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
A G P+P V W NGE + R+ + G + + D+G+Y C EN HG I AS
Sbjct: 350 AAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGTIYASA 408
Query: 367 PLEVTA-PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
L V A P F + P + A G + C+ + PK + W + T IL + + ++
Sbjct: 409 ELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT 468
Query: 424 DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
D L + ++R D+ Y C AEN G ++ +L++ +I L P D
Sbjct: 469 PDG-TLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDAT----KITLAPSSADINLG 523
Query: 484 TSVQMPCEIESVPPASID--WRKDGSRIVEDD------RISIT-VIGSLIIRNVSVTDTG 534
++ + C P + W D I D R ++ IG L I N + G
Sbjct: 524 DNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGG 583
Query: 535 RYECSA 540
+Y C A
Sbjct: 584 KYTCMA 589
Score = 105 bits (252), Expect = 1e-21
Identities = 63/221 (28%), Positives = 109/221 (49%), Gaps = 10/221 (4%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP++ +D E G N + C A G+P P + WLR+ E + ++NR E+ G L
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLA-SQNRVEVLA-GDLRFS 383
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ + D G+++C+A+N G ++ A++ V+ A + + PV P R +I
Sbjct: 384 KLSLEDSGMYQCVAENKHGTIYAS-AELAVQALAPDFR--LNPVRRLIPAARGGEI---- 436
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ C PK V W E ++ + R+ + +G+++I+N+ SD G YTC EN G
Sbjct: 437 -LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
K +++ L V + P++ +GDN+ C A P
Sbjct: 496 KANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDP 536
Score = 61.3 bits (142), Expect = 2e-08
Identities = 77/284 (27%), Positives = 97/284 (34%), Gaps = 22/284 (7%)
Query: 283 PVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSI 338
PVF P + E V+ C A P W NG M L R L +
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 339 LIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQT-AIIGDNVWFTCK 396
++ + DAGVY C N G +S L F + A G V C
Sbjct: 97 IMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCN 156
Query: 397 AKG-TPKPSIKWYRNTV--ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
P S +W N +P G +S NL + D Y C A +
Sbjct: 157 PPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFS 216
Query: 454 EASAV-------LTLEQVEIIPPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK- 504
S L E + P I + P + A V + C P I WRK
Sbjct: 217 TKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKV 276
Query: 505 DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDT 548
DGS + T +L I +VS D G YEC A N GRDT
Sbjct: 277 DGSLSPQ----WTTAEPTLQIPSVSFEDEGTYECEAENSKGRDT 316
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 143 bits (347), Expect = 3e-33
Identities = 111/399 (27%), Positives = 185/399 (46%), Gaps = 23/399 (5%)
Query: 183 QFESEPND-VEVSFGENAVFTCVATGE-PAPEILWLRDS--EVIPLNENRYEIFDNGTLM 238
+F E D V+ G + C P WL + IP + + G L
Sbjct: 134 EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLY 193
Query: 239 VHEANENDDGLFECMA-KNVAGKAHSKPAKMI-VRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N +D G + C+A ++ S +K + AE+ + AP + P + +A +
Sbjct: 194 IARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALV 253
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ V +C A G P P + W + L + + ++ I +V D G Y C+ E
Sbjct: 254 GQ-QVTLECFAFGNPVPRIKWR-KVDGSLSPQWTTAEP--TLQIPSVSFEDEGTYECEAE 309
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ + + V A P ++ V ++ A IG N+ + C A G P+P+++W RN L
Sbjct: 310 NSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS 369
Query: 417 TGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ VL+ D L +++ +D +Y C AEN G I ASA L V+ + P L P
Sbjct: 370 QNRVEVLAGD---LRFSKLSLEDSGMYQCVAENKHGTIYASAELA---VQALAPDFRLNP 423
Query: 476 ED--MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDT 533
+ A + + +PC+ + P A + W K +V R+++T G+LIIRN+S +D
Sbjct: 424 VRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDE 483
Query: 534 GRYECSAFNDYGRDTASVFLTVKD----NLLPGDAYVNI 568
G+Y C A N G+ ++ L+V+D L P A +N+
Sbjct: 484 GKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINL 522
Score = 112 bits (270), Expect = 7e-24
Identities = 95/366 (25%), Positives = 152/366 (41%), Gaps = 35/366 (9%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLMVHEANEND 246
P + G+ C A G P P I W + D + P TL + + D
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTA-----EPTLQIPSVSFED 300
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
+G +EC A+N G+ + ++IV+ A P ++ A I +++ + C
Sbjct: 301 EGTYECEAENSKGR-DTVQGRIIVQ---------AQPEWLKVISDTEADIG-SNLRWGCA 349
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
A G P+P V W NGE + R+ + G + + D+G+Y C EN HG I AS
Sbjct: 350 AAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGTIYASA 408
Query: 367 PLEVTA-PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
L V A P F + P + A G + C+ + PK + W + T IL + + ++
Sbjct: 409 ELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT 468
Query: 424 DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
D L + ++R D+ Y C AEN G ++ +L++ +I L P D
Sbjct: 469 PDG-TLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDAT----KITLAPSSADINLG 523
Query: 484 TSVQMPCEIESVPPASID--WRKDGSRIVEDD------RISIT-VIGSLIIRNVSVTDTG 534
++ + C P + W D I D R ++ IG L I N + G
Sbjct: 524 DNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGG 583
Query: 535 RYECSA 540
+Y C A
Sbjct: 584 KYTCMA 589
Score = 105 bits (252), Expect = 1e-21
Identities = 63/221 (28%), Positives = 109/221 (49%), Gaps = 10/221 (4%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP++ +D E G N + C A G+P P + WLR+ E + ++NR E+ G L
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLA-SQNRVEVLA-GDLRFS 383
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ + D G+++C+A+N G ++ A++ V+ A + + PV P R +I
Sbjct: 384 KLSLEDSGMYQCVAENKHGTIYAS-AELAVQALAPDFR--LNPVRRLIPAARGGEI---- 436
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ C PK V W E ++ + R+ + +G+++I+N+ SD G YTC EN G
Sbjct: 437 -LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
K +++ L V + P++ +GDN+ C A P
Sbjct: 496 KANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDP 536
Score = 62.1 bits (144), Expect = 1e-08
Identities = 79/293 (26%), Positives = 101/293 (34%), Gaps = 22/293 (7%)
Query: 274 AEEHKSPAPPVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NER 329
A E ++ PVF P + E V+ C A P W NG M L R
Sbjct: 28 ALESQTTFGPVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSR 87
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQT-AII 387
L +++ + DAGVY C N G +S L F + A
Sbjct: 88 HQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHE 147
Query: 388 GDNVWFTCKAKG-TPKPSIKWYRNTV--ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHC 444
G V C P S +W N +P G +S NL + D Y C
Sbjct: 148 GWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSC 207
Query: 445 RAENDGGMIEASAV-------LTLEQVEIIPPRIVLK-PEDMDAFKETSVQMPCEIESVP 496
A + S L E + P I + P + A V + C P
Sbjct: 208 LATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNP 267
Query: 497 PASIDWRK-DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDT 548
I WRK DGS + T +L I +VS D G YEC A N GRDT
Sbjct: 268 VPRIKWRKVDGSLSPQ----WTTAEPTLQIPSVSFEDEGTYECEAENSKGRDT 316
>AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 143 bits (347), Expect = 3e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 89 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAE 147
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ DC G P+P V
Sbjct: 148 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETA-RLDCQVQGRPQPEV 196
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 197 TWRINGIPVEELAKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 255
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 256 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 315
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L ++ +I P K + V C
Sbjct: 316 IRDLQANDTGRYFCLAANDQNNVTIMANLKVKDA----TQITQGPRSTIEKKGSRVTFTC 371
Query: 491 EIESVP--PASIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 372 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 425
Score = 109 bits (261), Expect = 9e-23
Identities = 83/351 (23%), Positives = 144/351 (41%), Gaps = 9/351 (2%)
Query: 213 ILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAKNVAGKAHSKPAKMIVR 271
I W+ + + R + NG L +D+ + C A + + + +R
Sbjct: 1 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLR 60
Query: 272 RKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNER 329
KA P +F + + ++ +C A GFP P + W M +
Sbjct: 61 VKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRV 120
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
HN ++ + V D G Y C EN G + + V A P ++ P + G+
Sbjct: 121 TYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE 180
Query: 390 NVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+ +G P+P + W N + + + + L L V D + C A N
Sbjct: 181 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN 240
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKETSVQMPCEIESVPPASIDW-RKDG 506
G++ A+A + + Q +P +I+ + A + ++ + C+ P S+ W +DG
Sbjct: 241 RHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDG 297
Query: 507 SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ +++D+R G+L IR++ DTGRY C A ND T L VKD
Sbjct: 298 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 85/364 (23%), Positives = 147/364 (40%), Gaps = 28/364 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 179 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 235
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 236 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 286
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 287 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 346
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 347 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 406
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 407 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 464
Query: 488 M---PCEIESVPPASIDWRKDGSRIVEDDRISI-TVIGSLIIRNVSVTDTGRY--ECSAF 541
+ P E + P D + + + S+ V G+ + ++ Y +A
Sbjct: 465 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 524
Query: 542 NDYG 545
N YG
Sbjct: 525 NKYG 528
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 143 bits (347), Expect = 3e-33
Identities = 111/399 (27%), Positives = 185/399 (46%), Gaps = 23/399 (5%)
Query: 183 QFESEPND-VEVSFGENAVFTCVATGE-PAPEILWLRDS--EVIPLNENRYEIFDNGTLM 238
+F E D V+ G + C P WL + IP + + G L
Sbjct: 134 EFSKEERDPVKAHEGWGVMLPCNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLY 193
Query: 239 VHEANENDDGLFECMA-KNVAGKAHSKPAKMI-VRRKAEEHKSPAPPVFVSTPQKRFAKI 296
+ N +D G + C+A ++ S +K + AE+ + AP + P + +A +
Sbjct: 194 IARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALV 253
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ V +C A G P P + W + L + + ++ I +V D G Y C+ E
Sbjct: 254 GQ-QVTLECFAFGNPVPRIKWR-KVDGSLSPQWTTAEP--TLQIPSVSFEDEGTYECEAE 309
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N G+ + + V A P ++ V ++ A IG N+ + C A G P+P+++W RN L
Sbjct: 310 NSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLAS 369
Query: 417 TGNL-VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ VL+ D L +++ +D +Y C AEN G I ASA L V+ + P L P
Sbjct: 370 QNRVEVLAGD---LRFSKLSLEDSGMYQCVAENKHGTIYASAELA---VQALAPDFRLNP 423
Query: 476 ED--MDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDT 533
+ A + + +PC+ + P A + W K +V R+++T G+LIIRN+S +D
Sbjct: 424 VRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDE 483
Query: 534 GRYECSAFNDYGRDTASVFLTVKD----NLLPGDAYVNI 568
G+Y C A N G+ ++ L+V+D L P A +N+
Sbjct: 484 GKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINL 522
Score = 112 bits (270), Expect = 7e-24
Identities = 95/366 (25%), Positives = 152/366 (41%), Gaps = 35/366 (9%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLMVHEANEND 246
P + G+ C A G P P I W + D + P TL + + D
Sbjct: 246 PAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTA-----EPTLQIPSVSFED 300
Query: 247 DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCT 306
+G +EC A+N G+ + ++IV+ A P ++ A I +++ + C
Sbjct: 301 EGTYECEAENSKGR-DTVQGRIIVQ---------AQPEWLKVISDTEADIG-SNLRWGCA 349
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
A G P+P V W NGE + R+ + G + + D+G+Y C EN HG I AS
Sbjct: 350 AAGKPRPTVRWLRNGEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGTIYASA 408
Query: 367 PLEVTA-PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
L V A P F + P + A G + C+ + PK + W + T IL + + ++
Sbjct: 409 ELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT 468
Query: 424 DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE 483
D L + ++R D+ Y C AEN G ++ +L++ +I L P D
Sbjct: 469 PDG-TLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDAT----KITLAPSSADINLG 523
Query: 484 TSVQMPCEIESVPPASID--WRKDGSRIVEDD------RISIT-VIGSLIIRNVSVTDTG 534
++ + C P + W D I D R ++ IG L I N + G
Sbjct: 524 DNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGG 583
Query: 535 RYECSA 540
+Y C A
Sbjct: 584 KYTCMA 589
Score = 105 bits (252), Expect = 1e-21
Identities = 63/221 (28%), Positives = 109/221 (49%), Gaps = 10/221 (4%)
Query: 181 QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
QP++ +D E G N + C A G+P P + WLR+ E + ++NR E+ G L
Sbjct: 326 QPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEPLA-SQNRVEVLA-GDLRFS 383
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ + D G+++C+A+N G ++ A++ V+ A + + PV P R +I
Sbjct: 384 KLSLEDSGMYQCVAENKHGTIYAS-AELAVQALAPDFR--LNPVRRLIPAARGGEI---- 436
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ C PK V W E ++ + R+ + +G+++I+N+ SD G YTC EN G
Sbjct: 437 -LIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMG 495
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
K +++ L V + P++ +GDN+ C A P
Sbjct: 496 KANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDP 536
Score = 61.3 bits (142), Expect = 2e-08
Identities = 77/284 (27%), Positives = 97/284 (34%), Gaps = 22/284 (7%)
Query: 283 PVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSI 338
PVF P + E V+ C A P W NG M L R L +
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 339 LIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQT-AIIGDNVWFTCK 396
++ + DAGVY C N G +S L F + A G V C
Sbjct: 97 IMNPTKAQDAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLPCN 156
Query: 397 AKG-TPKPSIKWYRNTV--ILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMI 453
P S +W N +P G +S NL + D Y C A +
Sbjct: 157 PPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFS 216
Query: 454 EASAV-------LTLEQVEIIPPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK- 504
S L E + P I + P + A V + C P I WRK
Sbjct: 217 TKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKV 276
Query: 505 DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDT 548
DGS + T +L I +VS D G YEC A N GRDT
Sbjct: 277 DGSLSPQ----WTTAEPTLQIPSVSFEDEGTYECEAENSKGRDT 316
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 143 bits (346), Expect = 4e-33
Identities = 105/354 (29%), Positives = 154/354 (43%), Gaps = 26/354 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G+ V C+A G P P I WLR S +P + Y+ N TL + + E DDG + C+A+
Sbjct: 252 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRATYQNH-NKTLQLLKVGEEDDGEYRCLAE 310
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G A R A A P ++ PQ ET+ + DC G P+P V
Sbjct: 311 NSLGSA----------RHAYYVTVEAAPYWLHKPQSHLYGPGETARL-DCQVQGRPQPEV 359
Query: 316 AWYFNG---ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
W NG E + +++ +Q G++++ NVQ SD V C+ N HG + A+ + V
Sbjct: 360 TWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 418
Query: 373 PPSFIVVPTNQT--AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLT 430
P+ I+ NQT A+ G + CKA G P PS++W + N L
Sbjct: 419 LPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLG 478
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC 490
+ ++ +D Y C A ND + A L + +I P K + V C
Sbjct: 479 IRDLQANDTGRYFCLAANDQNNVTIMANLKVTDAT----QITQGPRSTIEKKGSRVTFTC 534
Query: 491 EIESVPPA--SIDWRKDGSRIVE--DDRISITVIGSLIIRNVSVTDTGRYECSA 540
+ P SI WR DG + E D G L+I ++ +D G Y C A
Sbjct: 535 QASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVA 588
Score = 116 bits (279), Expect = 6e-25
Identities = 89/374 (23%), Positives = 157/374 (41%), Gaps = 10/374 (2%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTLMVHEANENDDGL 249
VEV GE+ V C P ++ +S+++ + ++ R + NG L +D+
Sbjct: 141 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 200
Query: 250 -FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPP--VFVSTPQKRFAKINETSVMFDCT 306
+ C A + + + +R KA P +F + + ++ +C
Sbjct: 201 DYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECI 260
Query: 307 ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
A GFP P + W M + HN ++ + V D G Y C EN G +
Sbjct: 261 AEGFPTPTIKWLRPSGPMPADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAY 320
Query: 367 PLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTV-ILPITGNLVLSDD 425
+ V A P ++ P + G+ C+ +G P+P + W N + + + +
Sbjct: 321 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 380
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP-EDMDAFKET 484
L L V D + C A N G++ A+A + + Q +P +I+ + A + +
Sbjct: 381 RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ---LPAKILTADNQTYMAVQGS 437
Query: 485 SVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFND 543
+ + C+ P S+ W +DG+ +++D+R G+L IR++ DTGRY C A ND
Sbjct: 438 TAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAND 497
Query: 544 YGRDTASVFLTVKD 557
T L V D
Sbjct: 498 QNNVTIMANLKVTD 511
Score = 101 bits (243), Expect = 1e-20
Identities = 100/398 (25%), Positives = 167/398 (41%), Gaps = 42/398 (10%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNE---NRYEIFDNGTLMVH 240
E P + V ++ C A+G+P + W RD P E Y+ +G+ +
Sbjct: 34 EQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTIT 93
Query: 241 EANEN----DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
N N G++ C A N G A S +++ + K PV V +
Sbjct: 94 GNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE------ 147
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSD-AGVYTC 353
SV+ C +P ++ N + + + +ER+ + NG++ NV SD Y C
Sbjct: 148 ---SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYIC 204
Query: 354 QVENIHGKI---SASVPLEVTAPPSFI------VVPTNQT----AIIGDNVWFTCKAKGT 400
+ + L V A S I + PTN + A+ G + C A+G
Sbjct: 205 HAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGF 264
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P+IKW R + +P + N+ L LL+V +DD Y C AEN G + +T
Sbjct: 265 PTPTIKWLRPSGPMP-ADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 323
Query: 461 LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDG---SRIVEDDRISI 517
+E P + KP+ + ++ C+++ P + WR +G + +D + I
Sbjct: 324 VEAA----PYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRI 379
Query: 518 TVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
G+LI+ NV +DT +C A N +G A+ ++ V
Sbjct: 380 Q-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYV 416
Score = 83.0 bits (196), Expect = 6e-15
Identities = 78/317 (24%), Positives = 131/317 (41%), Gaps = 25/317 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFE 251
GE A C G P PE+ W + IP+ E +Y I G L++ +D + +
Sbjct: 342 GETARLDCQVQGRPQPEVTWRING--IPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQ 398
Query: 252 CMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFP 311
C A+N G + +V+ P ++ + + + ++ C A G P
Sbjct: 399 CEARNRHGLLLANAYIYVVQ---------LPAKILTADNQTYMAVQGSTAYLLCKAFGAP 449
Query: 312 KPHVAWYF-NGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
P V W +G +L +ER NG++ I+++Q +D G Y C N ++ L+V
Sbjct: 450 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 509
Query: 371 TAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILPITGNL-VLSDDNQ 427
T P + G V FTC+A P +PSI W + L G+ ++
Sbjct: 510 TDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 569
Query: 428 NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ 487
L + + D Y C A + ++E+ A L + PR+VL D+ ++ V+
Sbjct: 570 RLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVL--SDLHLLTQSQVR 627
Query: 488 M---PCEIESVPPASID 501
+ P E + P D
Sbjct: 628 VSWSPAEDHNAPIEKYD 644
Score = 50.8 bits (116), Expect = 3e-05
Identities = 66/297 (22%), Positives = 109/297 (36%), Gaps = 22/297 (7%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERI---ILQ--HNG 336
PPV +R + C A+G P+ W +G E + + Q H+G
Sbjct: 29 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 88
Query: 337 SILI----KNVQNSDAGVYTCQVENIHG-KISASVPLEVTAPPSFIVVPTNQTAI-IGDN 390
S I N G+Y C N G +S + L P + + G++
Sbjct: 89 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 148
Query: 391 VWFTCKAKGTPKPSIKWYRNTVILPI-TGNLVLSDDNQNLTLLEV-TRDDDAIYHCRAEN 448
V C + +P ++ N+ IL I V N NL V T D+ + Y C A
Sbjct: 149 VVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHF 208
Query: 449 DG--GMIEASAV-LTLEQVEII---PPRIVL---KPEDMDAFKETSVQMPCEIESVPPAS 499
G +I+ + L ++ + PR++ + A + + + C E P +
Sbjct: 209 PGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPT 268
Query: 500 IDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I W + + D +L + V D G Y C A N G + ++TV+
Sbjct: 269 IKWLRPSGPMPADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 325
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 141 bits (342), Expect = 1e-32
Identities = 107/413 (25%), Positives = 178/413 (43%), Gaps = 36/413 (8%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPA-PEILWLRDSEVIPLN-ENRYEIFDNGTLMVH 240
+F SEP+D G N + C A + P I W +D + L + R + NG+L++
Sbjct: 41 RFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQ 100
Query: 241 EA-----NENDDGLFECMAK-NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
++ D+GL++C A +G S+ AK+ V P F+S + A
Sbjct: 101 NILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVA---------GPLRFLSQTESVTA 151
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVY 351
+ +T V+ C G P P + W N + + + R+++ +G++ I +Q D G+Y
Sbjct: 152 FMGDT-VLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIY 210
Query: 352 TCQVEN-IHGKISASVPLEVTAPPS------FIVVPTNQTAIIGDNVWFTCKAKGTPKPS 404
C N + + + + P F+ P+N AI G + C G P PS
Sbjct: 211 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPS 270
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
W R ++ + NL + VT DD +Y C I ASA LT+
Sbjct: 271 FTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV--- 327
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
++PP + P ++ A++ ++ C + P +++W K+G ++ D I +L
Sbjct: 328 -LVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLR 386
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAMRDV 577
I V +D G Y+C A N+ G S L V +P + L A RDV
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSS----VLPSAPRDV 435
Score = 137 bits (331), Expect = 3e-31
Identities = 99/383 (25%), Positives = 174/383 (45%), Gaps = 24/383 (6%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSE-VIPL-NENRYEIFDNGTLMVH 240
+F S+ V G+ + C GEP P I W ++ + + P+ ++R + +G L +
Sbjct: 141 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 200
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
D G++ C A+N A A++ + H+ F+ P A I
Sbjct: 201 RLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL---YFLQRPSNVVA-IEGKD 256
Query: 301 VMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ +C +G+P P W GE + L +++ L ++LI NV + D+G+YTC V
Sbjct: 257 AVLECCVSGYPPPSFTW-LRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYK 315
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPIT 417
+ ISAS L V PP F+ P+N A ++ F C G P P++ W +N V++P
Sbjct: 316 NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD 375
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-----TLEQVEIIP--PR 470
++ NL +L V + D+ Y C AEN+ G + SA L + ++P PR
Sbjct: 376 YFQIVG--GSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 433
Query: 471 IVLKPEDMDAFKETSVQMPCEIE-SVPPASIDWRKDGSRIVEDDRISITVIGS--LIIRN 527
V+ F S + P E + ++ ++ + ++G + ++ T GS L + N
Sbjct: 434 DVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN--RERALNTTQPGSLQLTVGN 491
Query: 528 VSVTDTGRYECSAFNDYGRDTAS 550
+ + A+N++G +S
Sbjct: 492 LKPEAMYTFRVVAYNEWGPGESS 514
Score = 97.1 bits (231), Expect = 4e-19
Identities = 59/204 (28%), Positives = 93/204 (45%), Gaps = 13/204 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+Q F P++V G++AV C +G P P WLR EVI L +Y + L++
Sbjct: 238 RQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLI 297
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
++D G++ C+ + S A++ V PP F++ P +A
Sbjct: 298 SNVTDDDSGMYTCVV-TYKNENISASAELTVL---------VPPWFLNHPSNLYA-YESM 346
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ F+CT +G P P V W NG+ ++ ++ + ++ I V SD G Y C EN
Sbjct: 347 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEA 406
Query: 360 GKISASVPLEVTAP--PSFIVVPT 381
G S L V P PS V+P+
Sbjct: 407 GNAQTSAQLIVPKPAIPSSSVLPS 430
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 141 bits (342), Expect = 1e-32
Identities = 107/413 (25%), Positives = 178/413 (43%), Gaps = 36/413 (8%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPA-PEILWLRDSEVIPLN-ENRYEIFDNGTLMVH 240
+F SEP+D G N + C A + P I W +D + L + R + NG+L++
Sbjct: 41 RFLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQ 100
Query: 241 EA-----NENDDGLFECMAK-NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
++ D+GL++C A +G S+ AK+ V P F+S + A
Sbjct: 101 NILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVA---------GPLRFLSQTESVTA 151
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVY 351
+ +T V+ C G P P + W N + + + R+++ +G++ I +Q D G+Y
Sbjct: 152 FMGDT-VLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIY 210
Query: 352 TCQVEN-IHGKISASVPLEVTAPPS------FIVVPTNQTAIIGDNVWFTCKAKGTPKPS 404
C N + + + + P F+ P+N AI G + C G P PS
Sbjct: 211 RCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPS 270
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
W R ++ + NL + VT DD +Y C I ASA LT+
Sbjct: 271 FTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTV--- 327
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
++PP + P ++ A++ ++ C + P +++W K+G ++ D I +L
Sbjct: 328 -LVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLR 386
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDAYVNIALTQAMRDV 577
I V +D G Y+C A N+ G S L V +P + L A RDV
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSS----VLPSAPRDV 435
Score = 137 bits (331), Expect = 3e-31
Identities = 99/383 (25%), Positives = 174/383 (45%), Gaps = 24/383 (6%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSE-VIPL-NENRYEIFDNGTLMVH 240
+F S+ V G+ + C GEP P I W ++ + + P+ ++R + +G L +
Sbjct: 141 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 200
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
D G++ C A+N A A++ + H+ F+ P A I
Sbjct: 201 RLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL---YFLQRPSNVVA-IEGKD 256
Query: 301 VMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ +C +G+P P W GE + L +++ L ++LI NV + D+G+YTC V
Sbjct: 257 AVLECCVSGYPPPSFTW-LRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYK 315
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPIT 417
+ ISAS L V PP F+ P+N A ++ F C G P P++ W +N V++P
Sbjct: 316 NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD 375
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-----TLEQVEIIP--PR 470
++ NL +L V + D+ Y C AEN+ G + SA L + ++P PR
Sbjct: 376 YFQIVG--GSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 433
Query: 471 IVLKPEDMDAFKETSVQMPCEIE-SVPPASIDWRKDGSRIVEDDRISITVIGS--LIIRN 527
V+ F S + P E + ++ ++ + ++G + ++ T GS L + N
Sbjct: 434 DVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN--RERALNTTQPGSLQLTVGN 491
Query: 528 VSVTDTGRYECSAFNDYGRDTAS 550
+ + A+N++G +S
Sbjct: 492 LKPEAMYTFRVVAYNEWGPGESS 514
Score = 97.1 bits (231), Expect = 4e-19
Identities = 59/204 (28%), Positives = 93/204 (45%), Gaps = 13/204 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+Q F P++V G++AV C +G P P WLR EVI L +Y + L++
Sbjct: 238 RQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLI 297
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
++D G++ C+ + S A++ V PP F++ P +A
Sbjct: 298 SNVTDDDSGMYTCVV-TYKNENISASAELTVL---------VPPWFLNHPSNLYA-YESM 346
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ F+CT +G P P V W NG+ ++ ++ + ++ I V SD G Y C EN
Sbjct: 347 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEA 406
Query: 360 GKISASVPLEVTAP--PSFIVVPT 381
G S L V P PS V+P+
Sbjct: 407 GNAQTSAQLIVPKPAIPSSSVLPS 430
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 141 bits (341), Expect = 2e-32
Identities = 102/372 (27%), Positives = 173/372 (46%), Gaps = 32/372 (8%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLM 238
+P+ E P ++ + + C A G P P+I W R D +P + +Y L
Sbjct: 226 EPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLP-GKVKYSK-SQAILE 283
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D+G +EC+A N+ G+ +K + APP + Q I +
Sbjct: 284 IPNFQQEDEGFYECIASNLRGRNLAKGQLIFY----------APPEWEQKIQNTHLSIYD 333
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+++++C A+G P P W NGER+ ERI ++ NG+++I + SD+GVY C EN
Sbjct: 334 -NLLWECKASGKPNPWYTWLKNGERLNPEERIQIE-NGTLIITMLNVSDSGVYQCAAENK 391
Query: 359 HGKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILP 415
+ I A+ L V A P F P + + + G ++ CK P+ +I W R T L
Sbjct: 392 YQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLR 451
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + L +D +L + +TR D Y C A N G + + L +++ +I + P
Sbjct: 452 QSKRIFLLEDG-SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVI----TVPP 506
Query: 476 EDMDAFKETSVQMPCEIESVPPASID--WRKDGSRI------VEDDRISITVIGSLIIRN 527
MD S+ +PC++ P + W +G I +RI +G L+IRN
Sbjct: 507 SKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRN 566
Query: 528 VSVTDTGRYECS 539
+ + +G+Y C+
Sbjct: 567 IQLHHSGKYLCT 578
Score = 118 bits (284), Expect = 1e-25
Identities = 90/336 (26%), Positives = 145/336 (43%), Gaps = 9/336 (2%)
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNV-AGKAHSKPAKMIVRRKAEEHKSPAPP 283
+ R+ + G L + + +D G + C N A ++ P +V+R P
Sbjct: 169 DNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPK 228
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
+ V P+ A ++SV +C A G P P ++W L + + + I N
Sbjct: 229 IEVRFPETIQAA-KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNF 287
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
Q D G Y C N+ G+ A L APP + N I DN+ + CKA G P P
Sbjct: 288 QQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNP 347
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
W +N L + + + +T+L V+ D +Y C AEN +I A+A L +
Sbjct: 348 WYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKYQIIYANAEL---R 402
Query: 464 VEIIPPRIVLKPEDMDAFKET--SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG 521
V P P +F + + + C+ + P A+I W++ + + RI + G
Sbjct: 403 VLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDG 462
Query: 522 SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
SL I N++ +D G Y C A N +G + L VK+
Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE 498
Score = 110 bits (265), Expect = 3e-23
Identities = 100/384 (26%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 181 QPQFESEPNDV----EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT 236
+P F EP+DV ++S E + C A G P+P W ++ I + + D G+
Sbjct: 25 RPIFTQEPHDVIFPLDLSKSE-VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGS 83
Query: 237 LMVHEANENDD-GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L ++ + + D G+++C+A N+ G S+ AK+ + V V Q
Sbjct: 84 LAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQ----- 138
Query: 296 INETSVMFDC-TATGFPKPHVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVY 351
V+ C F AW FN + + N R + Q G++ I V+ SD G Y
Sbjct: 139 ----GVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNY 194
Query: 352 TCQVENIHGKISASVP-----------LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
TC + N + S P + P + P A +V C A G
Sbjct: 195 TCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGN 254
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P I W R P+ G + S L + ++D+ Y C A N G A L
Sbjct: 255 PVPDISW-RRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQL- 312
Query: 461 LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI 520
+ PP K ++ ++ C+ P W K+G R+ ++RI I
Sbjct: 313 ---IFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIE-N 368
Query: 521 GSLIIRNVSVTDTGRYECSAFNDY 544
G+LII ++V+D+G Y+C+A N Y
Sbjct: 369 GTLIITMLNVSDSGVYQCAAENKY 392
Score = 66.5 bits (155), Expect = 6e-10
Identities = 71/285 (24%), Positives = 116/285 (40%), Gaps = 20/285 (7%)
Query: 283 PVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI 340
P+F P ++++ V+ +C A G+P PH W NG + + +G L
Sbjct: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
Query: 341 KNVQNS--DAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTC 395
N ++ D G+Y C N+ G I S L+ F T T + G V C
Sbjct: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDF-ETKTRSTVSVREGQGVVLLC 144
Query: 396 KAK---GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGM 452
G + + N + + +S + NL + +V D Y C N
Sbjct: 145 GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
Query: 453 --IEASAVLTLEQVEII----PPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK- 504
++ +++ + + P+I ++ PE + A K++SV++ C P I WR+
Sbjct: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
Query: 505 DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTA 549
DGS + + S + L I N D G YEC A N GR+ A
Sbjct: 265 DGSPLPGKVKYSKSQ-AILEIPNFQQEDEGFYECIASNLRGRNLA 308
Score = 64.9 bits (151), Expect = 2e-09
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 182 PQFESEPNDVE--VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P F P + V G + V C P I W R +E + ++ R + ++G+L +
Sbjct: 408 PDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDGSLKI 466
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D G + C+A N G A + +IV+ + V P K + E
Sbjct: 467 YNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERT---------VITVPPSKMDVTVGE- 515
Query: 300 SVMFDCTATGFPKPHVA--WYFNGERMLLN------ERIILQHNGSILIKNVQNSDAGVY 351
S++ C + P V W+FNG+ + L ERI + G ++I+N+Q +G Y
Sbjct: 516 SIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKY 575
Query: 352 TCQVENIHGKISASVPLEVTAPP 374
C V+ +SA + V PP
Sbjct: 576 LCTVQTTLESLSAVADIIVRGPP 598
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 141 bits (341), Expect = 2e-32
Identities = 102/372 (27%), Positives = 173/372 (46%), Gaps = 32/372 (8%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDNGTLM 238
+P+ E P ++ + + C A G P P+I W R D +P + +Y L
Sbjct: 226 EPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRLDGSPLP-GKVKYSK-SQAILE 283
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D+G +EC+A N+ G+ +K + APP + Q I +
Sbjct: 284 IPNFQQEDEGFYECIASNLRGRNLAKGQLIFY----------APPEWEQKIQNTHLSIYD 333
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+++++C A+G P P W NGER+ ERI ++ NG+++I + SD+GVY C EN
Sbjct: 334 -NLLWECKASGKPNPWYTWLKNGERLNPEERIQIE-NGTLIITMLNVSDSGVYQCAAENK 391
Query: 359 HGKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILP 415
+ I A+ L V A P F P + + + G ++ CK P+ +I W R T L
Sbjct: 392 YQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLR 451
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + L +D +L + +TR D Y C A N G + + L +++ +I + P
Sbjct: 452 QSKRIFLLEDG-SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVI----TVPP 506
Query: 476 EDMDAFKETSVQMPCEIESVPPASID--WRKDGSRI------VEDDRISITVIGSLIIRN 527
MD S+ +PC++ P + W +G I +RI +G L+IRN
Sbjct: 507 SKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRN 566
Query: 528 VSVTDTGRYECS 539
+ + +G+Y C+
Sbjct: 567 IQLHHSGKYLCT 578
Score = 118 bits (284), Expect = 1e-25
Identities = 90/336 (26%), Positives = 145/336 (43%), Gaps = 9/336 (2%)
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNV-AGKAHSKPAKMIVRRKAEEHKSPAPP 283
+ R+ + G L + + +D G + C N A ++ P +V+R P
Sbjct: 169 DNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPK 228
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
+ V P+ A ++SV +C A G P P ++W L + + + I N
Sbjct: 229 IEVRFPETIQAA-KDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAILEIPNF 287
Query: 344 QNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKP 403
Q D G Y C N+ G+ A L APP + N I DN+ + CKA G P P
Sbjct: 288 QQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNP 347
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
W +N L + + + +T+L V+ D +Y C AEN +I A+A L +
Sbjct: 348 WYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKYQIIYANAEL---R 402
Query: 464 VEIIPPRIVLKPEDMDAFKET--SVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG 521
V P P +F + + + C+ + P A+I W++ + + RI + G
Sbjct: 403 VLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDG 462
Query: 522 SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
SL I N++ +D G Y C A N +G + L VK+
Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE 498
Score = 110 bits (265), Expect = 3e-23
Identities = 100/384 (26%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 181 QPQFESEPNDV----EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGT 236
+P F EP+DV ++S E + C A G P+P W ++ I + + D G+
Sbjct: 25 RPIFTQEPHDVIFPLDLSKSE-VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGS 83
Query: 237 LMVHEANENDD-GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L ++ + + D G+++C+A N+ G S+ AK+ + V V Q
Sbjct: 84 LAINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQ----- 138
Query: 296 INETSVMFDC-TATGFPKPHVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVY 351
V+ C F AW FN + + N R + Q G++ I V+ SD G Y
Sbjct: 139 ----GVVLLCGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNY 194
Query: 352 TCQVENIHGKISASVP-----------LEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
TC + N + S P + P + P A +V C A G
Sbjct: 195 TCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGN 254
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P I W R P+ G + S L + ++D+ Y C A N G A L
Sbjct: 255 PVPDISW-RRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQL- 312
Query: 461 LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI 520
+ PP K ++ ++ C+ P W K+G R+ ++RI I
Sbjct: 313 ---IFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIE-N 368
Query: 521 GSLIIRNVSVTDTGRYECSAFNDY 544
G+LII ++V+D+G Y+C+A N Y
Sbjct: 369 GTLIITMLNVSDSGVYQCAAENKY 392
Score = 66.5 bits (155), Expect = 6e-10
Identities = 71/285 (24%), Positives = 116/285 (40%), Gaps = 20/285 (7%)
Query: 283 PVFVSTPQKRF--AKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILI 340
P+F P ++++ V+ +C A G+P PH W NG + + +G L
Sbjct: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
Query: 341 KNVQNS--DAGVYTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTC 395
N ++ D G+Y C N+ G I S L+ F T T + G V C
Sbjct: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDF-ETKTRSTVSVREGQGVVLLC 144
Query: 396 KAK---GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGM 452
G + + N + + +S + NL + +V D Y C N
Sbjct: 145 GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
Query: 453 --IEASAVLTLEQVEII----PPRIVLK-PEDMDAFKETSVQMPCEIESVPPASIDWRK- 504
++ +++ + + P+I ++ PE + A K++SV++ C P I WR+
Sbjct: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
Query: 505 DGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTA 549
DGS + + S + L I N D G YEC A N GR+ A
Sbjct: 265 DGSPLPGKVKYSKSQ-AILEIPNFQQEDEGFYECIASNLRGRNLA 308
Score = 64.9 bits (151), Expect = 2e-09
Identities = 53/203 (26%), Positives = 88/203 (43%), Gaps = 22/203 (10%)
Query: 182 PQFESEPNDVE--VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P F P + V G + V C P I W R +E + ++ R + ++G+L +
Sbjct: 408 PDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDGSLKI 466
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ +D G + C+A N G A + +IV+ + V P K + E
Sbjct: 467 YNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERT---------VITVPPSKMDVTVGE- 515
Query: 300 SVMFDCTATGFPKPHVA--WYFNGERMLLN------ERIILQHNGSILIKNVQNSDAGVY 351
S++ C + P V W+FNG+ + L ERI + G ++I+N+Q +G Y
Sbjct: 516 SIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKY 575
Query: 352 TCQVENIHGKISASVPLEVTAPP 374
C V+ +SA + V PP
Sbjct: 576 LCTVQTTLESLSAVADIIVRGPP 598
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 140 bits (338), Expect = 4e-32
Identities = 104/372 (27%), Positives = 166/372 (44%), Gaps = 29/372 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 319
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 320 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 368
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 369 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 425
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 426 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 485
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 486 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 541
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 542 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 547 DTASVFLTVKDN 558
D A +LTV N
Sbjct: 601 DLAKAYLTVLGN 612
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 227 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 344
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 402
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 458
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 459 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 518
Query: 556 KD 557
KD
Sbjct: 519 KD 520
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 394
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 395 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 445
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 506 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 566 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 168
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 169 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 228
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 229 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 288
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 289 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 343
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLD 427
Score = 44.4 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 12/186 (6%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S+ E+T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +
Sbjct: 32 SIQNELTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
Query: 423 SDDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
S ++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 151 VVQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 536 -YECSA 540
Y C+A
Sbjct: 210 DYSCNA 215
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 139 bits (337), Expect = 5e-32
Identities = 101/379 (26%), Positives = 166/379 (43%), Gaps = 23/379 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E ++ E G C+A G P P I W ++ ++P N Y+ F+ TL + +E
Sbjct: 268 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-TLQIIHVSE 326
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G ++C+AKN G H + VR K A P +++ PQ E +
Sbjct: 327 ADSGNYQCIAKNALGAIHH---TISVRVK-------AAPYWITAPQNLVLSPGEDGTLI- 375
Query: 305 CTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A G PKP ++W NG + + ++ +I+ NVQ + VY C N +G +
Sbjct: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
Query: 363 SASVPLEVTAPPSFIVVPTN--QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
A+ + V A P I+ P N I C G+P P+I+W++ + ++
Sbjct: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI 495
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ +N L + +D Y C A N GM + L ++ P IV +PE
Sbjct: 496 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD----PTWIVKQPEYAVV 551
Query: 481 FKETSVQMPCEIESVPPASID--WRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + V C+++ S+ W KD + D+R ++ L++ +VS D+G Y C
Sbjct: 552 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK-DHLVVADVSDDDSGTYTC 610
Query: 539 SAFNDYGRDTASVFLTVKD 557
A +AS L+V D
Sbjct: 611 VANTTLDSVSASAVLSVVD 629
Score = 104 bits (250), Expect = 2e-21
Identities = 79/289 (27%), Positives = 119/289 (41%), Gaps = 19/289 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS---EVIPLNENRYEIFDNGTLM 238
P + + P ++ +S GE+ C A G P P I WL + E+ P + +R D T++
Sbjct: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK--IDGDTII 412
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
E +++C A N G A V AE PP ++ + I
Sbjct: 413 FSNVQERSSAVYQCNASNEYGYLL---ANAFVNVLAE------PPRILTPANTLYQVIAN 463
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVEN 357
+ DC G P P + W+ + L+E I +L NG++ I Q G YTC N
Sbjct: 464 RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 523
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK--GTPKPSIKWYRNTVILP 415
G V LE+ P + P G V F CK K T ++ W ++ LP
Sbjct: 524 KLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 583
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ D +L + +V+ DD Y C A + ASAVL++ V
Sbjct: 584 SDERFTV--DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDV 630
Score = 104 bits (249), Expect = 2e-21
Identities = 78/283 (27%), Positives = 117/283 (41%), Gaps = 12/283 (4%)
Query: 282 PPVFVSTPQKRFAKINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI 338
PP F+ TP+ + E + +C A G P P + W + N + ++
Sbjct: 261 PPTFL-TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK 398
I +V +D+G Y C +N G I ++ + V A P +I P N G++ C+A
Sbjct: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
Query: 399 GTPKPSIKWYRNTVILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
G PKP I W N V + I + D + V A+Y C A N+ G + A+A
Sbjct: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
Query: 458 VLTLEQVEIIPPRIVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDR 514
+ V PPRI+ + + C P +I+W K GS + ED
Sbjct: 440 FV---NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ + G+L I TG Y C A N G V L +KD
Sbjct: 497 V-LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD 538
Score = 64.9 bits (151), Expect = 2e-09
Identities = 47/180 (26%), Positives = 79/180 (43%), Gaps = 16/180 (8%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 466 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS-VMFDCTA--TGFPKPHV 315
G A K E H P ++ Q +A + S V F+C V
Sbjct: 526 GMA-----------KNEVHLEIKDPTWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 573
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPS 375
W + + +ER + + +++ +V + D+G YTC +SAS L V P+
Sbjct: 574 LWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
Score = 57.2 bits (132), Expect = 4e-07
Identities = 54/194 (27%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 362 ISA-SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
ISA VPL++ PP+ I + + II +N+ C+AKG P PS W RN I
Sbjct: 27 ISALEVPLDLVQPPT-ITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDK 85
Query: 419 N-LVLSDDNQNLTLLEVTRDDDA-----IYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ LV ++ + + A +Y C A N+ G ++ ++ + +
Sbjct: 86 DPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEK 145
Query: 473 LKPEDMDAFKETSVQMPCEIE-SVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSV 530
L+P + + + S+ +PC +PP I W + R+ + +R+S + G L NV
Sbjct: 146 LEPITLQSGQ--SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLP 203
Query: 531 TDTGR-YECSA-FN 542
DT Y C A FN
Sbjct: 204 EDTREDYICYARFN 217
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 44 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 103
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 104 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 155
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 156 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 214
Query: 356 ENIHGK-ISASVPLEV 370
H + I P+ V
Sbjct: 215 RFNHTQTIQQKQPISV 230
Score = 43.6 bits (98), Expect = 0.005
Identities = 72/317 (22%), Positives = 114/317 (35%), Gaps = 45/317 (14%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 39 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 98
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 99 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 155
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNL----TLLEVTRDDDAIY-- 442
++ C+ G P P I W N+ V N +L L E TR+D Y
Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 215
Query: 443 --HCRAENDGGMIEASAVLTLEQVEIIP-----------------PRIVLKPEDMDAFKE 483
H + I + E + I P L PE + KE
Sbjct: 216 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 275
Query: 484 ----TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+ + C E +P I W K+ + ++ + +L I +VS D+G Y+C
Sbjct: 276 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 335
Query: 540 AFNDYGRDTASVFLTVK 556
A N G ++ + VK
Sbjct: 336 AKNALGAIHHTISVRVK 352
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 139 bits (336), Expect = 7e-32
Identities = 111/428 (25%), Positives = 184/428 (42%), Gaps = 27/428 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E ++ E G C+A G P P I W ++ ++P N Y+ F+ TL + +E
Sbjct: 269 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-TLQIIHVSE 327
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G ++C+AKN G H + VR K A P +++ PQ E +
Sbjct: 328 ADSGNYQCIAKNALGAIHH---TISVRVK-------AAPYWITAPQNLVLSPGEDGTLI- 376
Query: 305 CTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A G PKP ++W NG + + ++ +I+ NVQ + VY C N +G +
Sbjct: 377 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 436
Query: 363 SASVPLEVTAPPSFIVVPTN--QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
A+ + V A P I+ P N I C G+P P+I+W++ + ++
Sbjct: 437 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDI 496
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ +N L + +D Y C A N GM + L ++ P IV +PE
Sbjct: 497 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD----PTWIVKQPEYAVV 552
Query: 481 FKETSVQMPCEIESVPPASID--WRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + V C+++ S+ W KD + D+R ++ L++ +VS D+G Y C
Sbjct: 553 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK-DHLVVADVSDDDSGTYTC 611
Query: 539 SAFNDYGRDTASVFLT-VKDNLLPGDAY--VNIALTQAMRD-VDQAIERTVDQLFKNRSA 594
A +AS L+ V P Y N L + D +D++++ + N S
Sbjct: 612 VANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPLDLELTDQLDKSVQLSWTPGDDNNSP 671
Query: 595 VVNIGDLY 602
+ I D Y
Sbjct: 672 ITTIHDEY 679
Score = 103 bits (248), Expect = 3e-21
Identities = 78/286 (27%), Positives = 118/286 (41%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS---EVIPLNENRYEIFDNGTLM 238
P + + P ++ +S GE+ C A G P P I WL + E+ P + +R D T++
Sbjct: 356 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK--IDGDTII 413
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
E +++C A N G A V AE PP ++ + I
Sbjct: 414 FSNVQERSSAVYQCNASNEYGYLL---ANAFVNVLAE------PPRILTPANTLYQVIAN 464
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVEN 357
+ DC G P P + W+ + L+E I +L NG++ I Q G YTC N
Sbjct: 465 RPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 524
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK--GTPKPSIKWYRNTVILP 415
G V LE+ P + P G V F CK K T ++ W ++ LP
Sbjct: 525 KLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 584
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+ D +L + +V+ DD Y C A + ASAVL++
Sbjct: 585 SDERFTV--DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 628
Score = 103 bits (247), Expect = 4e-21
Identities = 78/283 (27%), Positives = 116/283 (40%), Gaps = 12/283 (4%)
Query: 282 PPVFVSTPQKRFAKINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI 338
PP F+ TP+ + E + +C A G P P + W + N + ++
Sbjct: 262 PPTFL-TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 320
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK 398
I +V +D+G Y C +N G I ++ + V A P +I P N G++ C+A
Sbjct: 321 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 380
Query: 399 GTPKPSIKWYRNTVILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
G PKP I W N V + I + D + V A+Y C A N+ G + A+A
Sbjct: 381 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 440
Query: 458 VLTLEQVEIIPPRIVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDR 514
+ V PPRI+ + + C P +I W K GS + ED
Sbjct: 441 FV---NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIY 497
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ + G+L I TG Y C A N G V L +KD
Sbjct: 498 V-LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD 539
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 45 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 104
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 105 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 156
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 157 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 215
Query: 356 ENIHGK-ISASVPLEV 370
H + I P+ V
Sbjct: 216 RFNHTQTIQQKQPISV 231
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 389 DNVWFTCKAKGTPKPSIKWYRNTVILPITGN-LVLSDDNQNLTLLEVTRDDDA-----IY 442
+N+ C+AKG P PS W RN I + LV ++ + + A +Y
Sbjct: 57 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 116
Query: 443 HCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIE-SVPPASID 501
C A N+ G ++ ++ + + L+P + + + S+ +PC +PP I
Sbjct: 117 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ--SLVLPCRPPIGLPPPIIF 174
Query: 502 WRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGR-YECSA-FN 542
W + R+ + +R+S + G L NV DT Y C A FN
Sbjct: 175 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 218
Score = 43.6 bits (98), Expect = 0.005
Identities = 72/317 (22%), Positives = 114/317 (35%), Gaps = 45/317 (14%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 40 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 99
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 100 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 156
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNL----TLLEVTRDDDAIY-- 442
++ C+ G P P I W N+ V N +L L E TR+D Y
Sbjct: 157 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 216
Query: 443 --HCRAENDGGMIEASAVLTLEQVEIIP-----------------PRIVLKPEDMDAFKE 483
H + I + E + I P L PE + KE
Sbjct: 217 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 276
Query: 484 ----TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+ + C E +P I W K+ + ++ + +L I +VS D+G Y+C
Sbjct: 277 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 336
Query: 540 AFNDYGRDTASVFLTVK 556
A N G ++ + VK
Sbjct: 337 AKNALGAIHHTISVRVK 353
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 319
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 320 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 368
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 369 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 425
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 426 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 485
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 486 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 541
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 542 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 601 DLAKAYLTV 609
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 227 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 344
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 402
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 458
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 459 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 518
Query: 556 KD 557
KD
Sbjct: 519 KD 520
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 394
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 395 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 445
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 506 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 566 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 168
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 169 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 228
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 229 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 288
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 289 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 343
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLD 427
Score = 44.4 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 12/186 (6%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S+ E+T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +
Sbjct: 32 SIQNELTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
Query: 423 SDDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
S ++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 151 VVQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 536 -YECSA 540
Y C+A
Sbjct: 210 DYSCNA 215
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 230 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 288
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 289 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 337
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 338 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 394
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 395 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 454
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 455 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 510
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 511 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 569
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 570 DLAKAYLTV 578
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 136 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 195
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 196 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 253
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 254 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 313
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 314 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 371
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 372 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 427
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 428 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 487
Query: 556 KD 557
KD
Sbjct: 488 KD 489
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 306 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 363
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 364 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 414
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 415 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 474
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 475 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 534
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 535 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 578
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 26 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 85
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 86 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 137
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 138 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 197
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 198 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 257
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 258 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 312
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 313 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 372
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 373 AVYQCNTSNEHGYLLANAFVSVLD 396
Score = 44.4 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 12/186 (6%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S+ E+T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +
Sbjct: 1 SIQNELTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRV 59
Query: 423 SDDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
S ++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 60 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 119
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 120 VVQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 178
Query: 536 -YECSA 540
Y C+A
Sbjct: 179 DYSCNA 184
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 248 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 306
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 307 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 355
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 356 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 412
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 413 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 472
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 473 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 528
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 529 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 587
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 588 DLAKAYLTV 596
Score = 106 bits (254), Expect = 6e-22
Identities = 72/263 (27%), Positives = 119/263 (45%), Gaps = 12/263 (4%)
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
++ +C A+G P P +AWY G + ++ N ++ I NV D+G Y C N G
Sbjct: 251 LLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 310
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PIT 417
I ++ + V A P ++ P N G++ C+A G PKP+++W N L P
Sbjct: 311 SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPN 370
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N ++ D + + A+Y C N+ G + A+A +++ V PPR +L P +
Sbjct: 371 PNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRN 424
Query: 478 --MDAFKETSVQMPCEIESVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTG 534
+ ++ C P ++ W K+G ++ + GSL I+ + D G
Sbjct: 425 QLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQG 484
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A N G+ V L VKD
Sbjct: 485 IYTCVATNILGKAENQVRLEVKD 507
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 324 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 381
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 382 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 432
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 433 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 492
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 493 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 552
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 553 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 596
Score = 71.7 bits (168), Expect = 2e-11
Identities = 87/401 (21%), Positives = 165/401 (41%), Gaps = 53/401 (13%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFD-NGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + ++ R + +GTL++ + E +G +
Sbjct: 27 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 86
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 87 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPP--------GL 138
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNG-----SILIKNVQNS--------------DAGV 350
P P + W + E + ++R+ HNG +++++++Q
Sbjct: 139 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 198
Query: 351 YTCQVENIHGKISASV---PLEVTA------PPSFIV---VPTNQTAIIGDNVWFTCKAK 398
+T +V H +S+ P +A PSF+ ++Q + G ++ C A
Sbjct: 199 FTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 258
Query: 399 GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
G P P I WY+ LP + + N+ L + V+ +D Y C A N G I +
Sbjct: 259 GVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 317
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISI 517
+ ++ P + +P+++ ++ C P ++ W +G + +
Sbjct: 318 VRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 373
Query: 518 TVIG-SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
V G ++I R+ ++ Y+C+ N++G A+ F++V D
Sbjct: 374 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 414
Score = 46.8 bits (106), Expect = 5e-04
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 12/185 (6%)
Query: 366 VPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
+P+++T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +S
Sbjct: 3 IPMDLTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 61
Query: 424 DDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 62 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV 121
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR- 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 122 VQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 180
Query: 536 YECSA 540
Y C+A
Sbjct: 181 YSCNA 185
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 255 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 313
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 314 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 362
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 363 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 419
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 420 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 479
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 480 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 535
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 536 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 594
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 595 DLAKAYLTV 603
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 220
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 221 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 278
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 279 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 338
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 339 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 396
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 397 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 452
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 453 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 512
Query: 556 KD 557
KD
Sbjct: 513 KD 514
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 331 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 388
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 389 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 439
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 440 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 499
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 500 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 559
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 560 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 603
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 162
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 163 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 222
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 223 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 282
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 283 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 337
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 338 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 397
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 398 AVYQCNTSNEHGYLLANAFVSVLD 421
Score = 46.8 bits (106), Expect = 5e-04
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 12/185 (6%)
Query: 366 VPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
+P+++T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +S
Sbjct: 27 IPMDLTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 424 DDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV 145
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR- 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 146 VQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 204
Query: 536 YECSA 540
Y C+A
Sbjct: 205 YSCNA 209
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 319
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 320 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 368
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 369 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 425
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 426 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 485
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 486 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 541
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 542 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 601 DLAKAYLTV 609
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 227 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 344
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 402
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 458
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 459 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 518
Query: 556 KD 557
KD
Sbjct: 519 KD 520
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 394
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 395 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 445
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 506 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 566 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 168
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 169 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 228
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 229 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 288
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 289 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 343
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLD 427
Score = 44.4 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 12/186 (6%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S+ E+T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +
Sbjct: 32 SIQNELTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
Query: 423 SDDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
S ++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 151 VVQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 536 -YECSA 540
Y C+A
Sbjct: 210 DYSCNA 215
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 261 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 319
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 320 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 368
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 369 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 425
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 426 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 485
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 486 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 541
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 542 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 600
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 601 DLAKAYLTV 609
Score = 108 bits (260), Expect = 1e-22
Identities = 90/362 (24%), Positives = 152/362 (41%), Gaps = 19/362 (5%)
Query: 207 GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGL-FECMAK----NVAGKA 261
G P+P I W+ S + R NG L D + C A+ + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 262 HSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG 321
+ K++ R E ++P+ T + + ++ +C A+G P P +AWY G
Sbjct: 227 NPFTLKVLTTRGVAE-RTPSFMYPQGTASSQMV-LRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 322 ERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPT 381
+ ++ N ++ I NV D+G Y C N G I ++ + V A P ++ P
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPK 344
Query: 382 NQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PITGNLVLSDDNQNLTLLEVTRDD 438
N G++ C+A G PKP+++W N L P N ++ D + +
Sbjct: 345 NLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISS 402
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED--MDAFKETSVQMPCEIESVP 496
A+Y C N+ G + A+A +++ V PPR +L P + + ++ C P
Sbjct: 403 RAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRNQLIRVILYNRTRLDCPFFGSP 458
Query: 497 PASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ W K+G ++ + GSL I+ + D G Y C A N G+ V L V
Sbjct: 459 IPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEV 518
Query: 556 KD 557
KD
Sbjct: 519 KD 520
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 337 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 394
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 395 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 445
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 446 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 505
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 506 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 566 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 89.4 bits (212), Expect = 7e-17
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 36/384 (9%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPL-NENRYEI-FDNGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + + R + +GTL++ + E +G +
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCN--------PPPGL 168
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQ-----VENIHGKIS 363
P P + W + E + ++R+ HNG + NV D Y+C I K
Sbjct: 169 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 228
Query: 364 ASVPLEVT-----APPSFIV---VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
++ + T PSF+ ++Q + G ++ C A G P P I WY+ LP
Sbjct: 229 FTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP 288
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
+ + N+ L + V+ +D Y C A N G I + + ++ P + +P
Sbjct: 289 -SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAA----PYWLDEP 343
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDT 533
+++ ++ C P ++ W +G + + V G ++I R+ ++
Sbjct: 344 KNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSR 403
Query: 534 GRYECSAFNDYGRDTASVFLTVKD 557
Y+C+ N++G A+ F++V D
Sbjct: 404 AVYQCNTSNEHGYLLANAFVSVLD 427
Score = 44.4 bits (100), Expect = 0.003
Identities = 48/186 (25%), Positives = 77/186 (41%), Gaps = 12/186 (6%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S+ E+T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +
Sbjct: 32 SIQNELTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRV 90
Query: 423 SDDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
S ++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 91 SMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPV 150
Query: 477 DMDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 151 VVQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 536 -YECSA 540
Y C+A
Sbjct: 210 DYSCNA 215
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 272 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 330
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 331 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 379
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 380 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 436
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 437 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 496
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 497 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 552
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 553 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 611
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 612 DLAKAYLTV 620
Score = 106 bits (254), Expect = 6e-22
Identities = 72/263 (27%), Positives = 119/263 (45%), Gaps = 12/263 (4%)
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
++ +C A+G P P +AWY G + ++ N ++ I NV D+G Y C N G
Sbjct: 275 LLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 334
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PIT 417
I ++ + V A P ++ P N G++ C+A G PKP+++W N L P
Sbjct: 335 SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPN 394
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N ++ D + + A+Y C N+ G + A+A +++ V PPR +L P +
Sbjct: 395 PNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRN 448
Query: 478 --MDAFKETSVQMPCEIESVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTG 534
+ ++ C P ++ W K+G ++ + GSL I+ + D G
Sbjct: 449 QLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQG 508
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A N G+ V L VKD
Sbjct: 509 IYTCVATNILGKAENQVRLEVKD 531
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 348 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 405
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 406 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 456
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 457 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 516
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 517 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 577 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 620
Score = 71.7 bits (168), Expect = 2e-11
Identities = 87/401 (21%), Positives = 165/401 (41%), Gaps = 53/401 (13%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFD-NGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + ++ R + +GTL++ + E +G +
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPP--------GL 162
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNG-----SILIKNVQNS--------------DAGV 350
P P + W + E + ++R+ HNG +++++++Q
Sbjct: 163 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 222
Query: 351 YTCQVENIHGKISASV---PLEVTA------PPSFIV---VPTNQTAIIGDNVWFTCKAK 398
+T +V H +S+ P +A PSF+ ++Q + G ++ C A
Sbjct: 223 FTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 282
Query: 399 GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
G P P I WY+ LP + + N+ L + V+ +D Y C A N G I +
Sbjct: 283 GVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 341
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISI 517
+ ++ P + +P+++ ++ C P ++ W +G + +
Sbjct: 342 VRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 397
Query: 518 TVIG-SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
V G ++I R+ ++ Y+C+ N++G A+ F++V D
Sbjct: 398 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 438
Score = 46.8 bits (106), Expect = 5e-04
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 12/185 (6%)
Query: 366 VPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
+P+++T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +S
Sbjct: 27 IPMDLTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 424 DDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV 145
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR- 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 146 VQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 204
Query: 536 YECSA 540
Y C+A
Sbjct: 205 YSCNA 209
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 69 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 127
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 128 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 176
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 177 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 233
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 234 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 293
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 294 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 349
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 350 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 408
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 409 DLAKAYLTV 417
Score = 106 bits (254), Expect = 6e-22
Identities = 72/263 (27%), Positives = 119/263 (45%), Gaps = 12/263 (4%)
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
++ +C A+G P P +AWY G + ++ N ++ I NV D+G Y C N G
Sbjct: 72 LLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 131
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PIT 417
I ++ + V A P ++ P N G++ C+A G PKP+++W N L P
Sbjct: 132 SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPN 191
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N ++ D + + A+Y C N+ G + A+A +++ V PPR +L P +
Sbjct: 192 PNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRN 245
Query: 478 --MDAFKETSVQMPCEIESVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTG 534
+ ++ C P ++ W K+G ++ + GSL I+ + D G
Sbjct: 246 QLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQG 305
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A N G+ V L VKD
Sbjct: 306 IYTCVATNILGKAENQVRLEVKD 328
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 145 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 202
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 203 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 253
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 254 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 313
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 314 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 373
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 374 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 417
Score = 60.9 bits (141), Expect = 3e-08
Identities = 54/240 (22%), Positives = 100/240 (41%), Gaps = 21/240 (8%)
Query: 334 HNGSILIKNVQNSDAGV-YTCQVE-----NIHGKISASVPLEVTA-----PPSFIV---V 379
HNG + NV D Y+C I K ++ + T PSF+
Sbjct: 1 HNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGT 60
Query: 380 PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD 439
++Q + G ++ C A G P P I WY+ LP + + N+ L + V+ +D
Sbjct: 61 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDS 119
Query: 440 AIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPAS 499
Y C A N G I + + ++ P + +P+++ ++ C P +
Sbjct: 120 GEYFCLASNKMGSIRHTISVRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGNPKPT 175
Query: 500 IDWRKDGSRIVE-DDRISITVIG-SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ W +G + + V G ++I R+ ++ Y+C+ N++G A+ F++V D
Sbjct: 176 VQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 235
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 138 bits (335), Expect = 9e-32
Identities = 103/369 (27%), Positives = 165/369 (44%), Gaps = 29/369 (7%)
Query: 196 GENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAK 255
G + + C+A+G P P+I W + +P ++ ++E F N L + +E D G + C+A
Sbjct: 325 GMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENF-NKALRITNVSEEDSGEYFCLAS 383
Query: 256 NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHV 315
N G + VR K A P ++ P+ E + C A G PKP V
Sbjct: 384 NKMGSIRH---TISVRVK-------AAPYWLDEPKNLILAPGEDGRLV-CRANGNPKPTV 432
Query: 316 AWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
W NGE + N + +I+ ++ Q S VY C N HG + A+ + V
Sbjct: 433 QWMVNGEPLQSAPPNPNREVA---GDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSV 489
Query: 371 TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQN 428
P ++ P NQ I+ + C G+P P+++W++N + G +N +
Sbjct: 490 LDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS 549
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQM 488
L + + ++D IY C A N G E L ++ P RI PED A + T+VQ+
Sbjct: 550 LEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKD----PTRIYRMPEDQVARRGTTVQL 605
Query: 489 PCEIESVP--PASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGR 546
C ++ P ++ W KD + +R+ SL I V+ D G Y C A + +
Sbjct: 606 ECRVKHDPSLKLTVSWLKDDEPLYIGNRMK-KEDDSLTIFGVAERDQGSYTCVASTELDQ 664
Query: 547 DTASVFLTV 555
D A +LTV
Sbjct: 665 DLAKAYLTV 673
Score = 106 bits (254), Expect = 6e-22
Identities = 72/263 (27%), Positives = 119/263 (45%), Gaps = 12/263 (4%)
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
++ +C A+G P P +AWY G + ++ N ++ I NV D+G Y C N G
Sbjct: 328 LLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 387
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL---PIT 417
I ++ + V A P ++ P N G++ C+A G PKP+++W N L P
Sbjct: 388 SIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPN 447
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
N ++ D + + A+Y C N+ G + A+A +++ V PPR +L P +
Sbjct: 448 PNREVAGD--TIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDV---PPR-MLSPRN 501
Query: 478 --MDAFKETSVQMPCEIESVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTG 534
+ ++ C P ++ W K+G ++ + GSL I+ + D G
Sbjct: 502 QLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQG 561
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
Y C A N G+ V L VKD
Sbjct: 562 IYTCVATNILGKAENQVRLEVKD 584
Score = 103 bits (247), Expect = 4e-21
Identities = 79/286 (27%), Positives = 124/286 (43%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLM 238
P + EP ++ ++ GE+ C A G P P + W+ + E + P N NR D T++
Sbjct: 401 PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TII 458
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + +++C N G + ++ PP +S + I
Sbjct: 459 FRDTQISSRAVYQCNTSNEHGYLLANAFVSVL---------DVPPRMLSPRNQLIRVILY 509
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNE-RIILQHNGSILIKNVQNSDAGVYTCQVEN 357
DC G P P + W+ NG+ L+ + NGS+ IK ++ D G+YTC N
Sbjct: 510 NRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATN 569
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP--KPSIKWYRNTVILP 415
I GK V LEV P +P +Q A G V C+ K P K ++ W ++ L
Sbjct: 570 ILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 629
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
I GN + +D+ +LT+ V D Y C A + A A LT+
Sbjct: 630 I-GNRMKKEDD-SLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 673
Score = 71.7 bits (168), Expect = 2e-11
Identities = 87/401 (21%), Positives = 165/401 (41%), Gaps = 53/401 (13%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFD-NGTLMVHEAN----ENDDGLF 250
+N + C A G PAP W R+S + ++ R + +GTL++ + E +G +
Sbjct: 104 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 163
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
+C A+N G A S ++ V + K PV V + N G
Sbjct: 164 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPP--------GL 215
Query: 311 PKPHVAWYFNG-ERMLLNERIILQHNG-----SILIKNVQNS--------------DAGV 350
P P + W + E + ++R+ HNG +++++++Q
Sbjct: 216 PSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNP 275
Query: 351 YTCQVENIHGKISASV---PLEVTA------PPSFIV---VPTNQTAIIGDNVWFTCKAK 398
+T +V H +S+ P +A PSF+ ++Q + G ++ C A
Sbjct: 276 FTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIAS 335
Query: 399 GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAV 458
G P P I WY+ LP + + N+ L + V+ +D Y C A N G I +
Sbjct: 336 GVPTPDIAWYKKGGDLP-SDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTIS 394
Query: 459 LTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISI 517
+ ++ P + +P+++ ++ C P ++ W +G + +
Sbjct: 395 VRVKAA----PYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNR 450
Query: 518 TVIG-SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
V G ++I R+ ++ Y+C+ N++G A+ F++V D
Sbjct: 451 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLD 491
Score = 46.8 bits (106), Expect = 5e-04
Identities = 47/185 (25%), Positives = 78/185 (42%), Gaps = 12/185 (6%)
Query: 366 VPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS 423
+P+++T PP+ I + + I+ DN+ C+AKG P PS W RN+ I + +S
Sbjct: 80 IPMDLTQPPT-ITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 138
Query: 424 DDNQNLTLLEVTR------DDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED 477
++ TL+ R + + Y C A N G ++ + + P+ L P
Sbjct: 139 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVV 198
Query: 478 MDAFKETSVQMPCEIESVPPASIDWRKDGSR-IVEDDRISITVIGSLIIRNVSVTDTGR- 535
+ ++Q +P I W I +D R+S G L NV + D
Sbjct: 199 VQEGAPLTLQCN-PPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTD 257
Query: 536 YECSA 540
Y C+A
Sbjct: 258 YSCNA 262
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 138 bits (334), Expect = 1e-31
Identities = 114/391 (29%), Positives = 173/391 (44%), Gaps = 38/391 (9%)
Query: 192 EVSFGENAVFTCVATGEPAPEILW-LRDSEVIPL---------NENRYEIFDNGTLMVHE 241
+V G++ C A+G P PEI W L D +I RY +F+NGTL ++
Sbjct: 2049 QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNK 2108
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++G + C A+N GK K ++ + AP + S + K +T+V
Sbjct: 2109 VGVAEEGDYTCYAQNTLGKDEMKVHLTVI--------TAAPRIRQSNKTNKRIKAGDTAV 2160
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ DC TG PKP + W M+ +R NGS+ I V+ D+G Y C N
Sbjct: 2161 L-DCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPS 2219
Query: 360 GKISASVPLEVTA-PPSFIVVPTNQTAIIGDNV-----WFTCKAKGTPKPSIKWYR-NTV 412
G + L+V + PP + TN+T I V F C+A+GTP P + W + +
Sbjct: 2220 GDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNI 2279
Query: 413 IL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
L P G+ + N L + V D A + C A N+GG E+ V+ LE +E++
Sbjct: 2280 FLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGG--ESVLVVQLEVLEMLRRP 2337
Query: 471 IVLKP--EDMDAFKETSVQMPCEIESVPPASIDW-RKDGSRI---VEDDRISITVIGSLI 524
P E + A S + C ++ PP I W +G+R + + I GS I
Sbjct: 2338 TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI 2397
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
I + D G+Y C+A N G V L +
Sbjct: 2398 ISKTTREDAGKYRCAARNKVGYIEKLVILEI 2428
Score = 134 bits (323), Expect = 3e-30
Identities = 103/384 (26%), Positives = 164/384 (42%), Gaps = 26/384 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLMVHEAN 243
+S + + G+ AV C TG+P P+I WL S ++I + +RY NG+L +++
Sbjct: 2145 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 2204
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
D G + C+A+N +G +K K+ V K ++ + + + + F
Sbjct: 2205 LLDSGEYVCVARNPSGD-DTKMYKLDVVSKPPLING----LYTNRTVIKATAVRHSKKHF 2259
Query: 304 DCTATGFPKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
DC A G P P V W L RI + NG++ I+NV+ SD+ + C N
Sbjct: 2260 DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEG 2319
Query: 360 GKISASVPLEV---TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
G+ V LEV P+F P N+ A +G + C G P P I W
Sbjct: 2320 GESVLVVQLEVLEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTR 2378
Query: 415 PITG---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
G L N + + + TR+D Y C A N G IE +L + Q +I +
Sbjct: 2379 FSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVI---L 2435
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI----GSLIIRN 527
P + S+ + C + +P +I W +V+ +I+ I G+L+I+
Sbjct: 2436 TYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKE 2495
Query: 528 VSVTDTGRYECSAFNDYGRDTASV 551
+ D G Y C A N G +V
Sbjct: 2496 ATAYDRGNYICKAQNSVGHTLITV 2519
Score = 132 bits (319), Expect = 8e-30
Identities = 102/375 (27%), Positives = 164/375 (43%), Gaps = 31/375 (8%)
Query: 201 FTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNV 257
F C A G P+PE++W+ + P +R + NGTL + +D F C+A+N
Sbjct: 2259 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 2318
Query: 258 AGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW 317
G++ ++V+ + E P F + ++ S +C+ G P P + W
Sbjct: 2319 GGES-----VLVVQLEVLEMLRR--PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 2371
Query: 318 YF-NGERML---LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
NG R + + ++ NGS +I DAG Y C N G I V LE+
Sbjct: 2372 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 2431
Query: 374 PSFIV-VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT---VILP-ITGNLVLSDDNQN 428
P + P I G+++ C + G PKP+IKW + V P I G +L D N
Sbjct: 2432 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGT 2490
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQ 487
L + E T D Y C+A+N G + + + PPRI +P + + Q
Sbjct: 2491 LVIKEATAYDRGNYICKAQNSVGH---TLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQ 2547
Query: 488 MPCEIESVPPASIDWRKDGSRIVED---DRI----SITVIGSLIIRNVSVTDTGRYECSA 540
+ C VP I W ++ +R + + G+L+I+N +D+G Y+C+A
Sbjct: 2548 LHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTA 2607
Query: 541 FNDYGRDTASVFLTV 555
N G D A+ ++ V
Sbjct: 2608 KNPLGSDYAATYIQV 2622
Score = 121 bits (292), Expect = 2e-26
Identities = 95/380 (25%), Positives = 160/380 (42%), Gaps = 31/380 (8%)
Query: 198 NAVFTCVATGEPAPEILWLRDSEVIPLNE----NRYEIFDNGTLMVHEANENDDGLFECM 253
+A C A G P P I W R + L++ +R ++ NGTL + D G + C
Sbjct: 1665 DAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCS 1724
Query: 254 AKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKP 313
A N+ G H +V PP + K + ++V C A G P P
Sbjct: 1725 ASNLFGTDHLHVTLSVV---------SYPPRILERRTKEITVHSGSTVELKCRAEGRPSP 1775
Query: 314 HVAWYFNGERMLL-----NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
V W + ++ + + ++ +G++++ N+ D G Y C N G+ S V +
Sbjct: 1776 TVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKI 1835
Query: 369 EVTAPPSFIVVPTNQTAI--IGDNVWFTCKAKGTPKPSIKWYRN--TVILPI--TGNLVL 422
+V A P I+ Q + G+++ C AKGTP+PS+ W + T + P+ T + +
Sbjct: 1836 QVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLF 1895
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI-VLKPEDMDAF 481
N L + + D Y C A + G +LT+E+ + PRI + +
Sbjct: 1896 LFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEE-RVTSPRIEAASQKRTEVN 1954
Query: 482 KETSVQMPCEIESVPPASIDWRKDGSRIVEDDR-----ISITVIGSLIIRNVSVTDTGRY 536
+ + C P I WR +V+ I + GSL I +V+ D+G Y
Sbjct: 1955 FGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVY 2014
Query: 537 ECSAFNDYGRDTASVFLTVK 556
C A N G D + ++++
Sbjct: 2015 LCVARNKMGDDLILMHVSLR 2034
Score = 117 bits (281), Expect = 3e-25
Identities = 107/395 (27%), Positives = 167/395 (42%), Gaps = 39/395 (9%)
Query: 192 EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRY----EIFDNGTLMVHEANENDD 247
EV+FG+ + C ATGEP P+I+W S+ + ++R ++ NG+L + E D
Sbjct: 1952 EVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDS 2011
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
G++ C+A+N G M V + + K F R ++ DC A
Sbjct: 2012 GVYLCVARNKMG---DDLILMHVSLRLKPAKIDHKQYF------RKQVLHGKDFQVDCKA 2062
Query: 308 TGFPKPHVAWYFNGERMLLN-----------ERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+G P P ++W M+ N R L +NG++ V ++ G YTC +
Sbjct: 2063 SGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQ 2122
Query: 357 NIHGKISASVPLEV-TAPPSFIVV-PTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-NTVI 413
N GK V L V TA P TN+ GD C+ G PKP I W + +
Sbjct: 2123 NTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDM 2182
Query: 414 LPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVL 473
+ + + N +LT+ +V D Y C A N G + + + L+ V PP I
Sbjct: 2183 ISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSG--DDTKMYKLDVVSK-PPLING 2239
Query: 474 KPEDMDAFKETSVQ-----MPCEIESVPPASIDWRKDGSRIVE----DDRISITVIGSLI 524
+ K T+V+ C E P + W + + RI++ G+L
Sbjct: 2240 LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLE 2299
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
IRNV ++D+ + C A N+ G V L V + L
Sbjct: 2300 IRNVRLSDSADFICVARNEGGESVLVVQLEVLEML 2334
Score = 111 bits (266), Expect = 2e-23
Identities = 103/400 (25%), Positives = 162/400 (40%), Gaps = 41/400 (10%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYE----IFDNGTLMVH 240
E ++ V G C A G P+P + W+ ++ + ++ + +GTL++H
Sbjct: 1749 ERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLH 1808
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
+ D G ++C+A N G+ ++V+ + APPV + ++ S
Sbjct: 1809 NLSIYDRGFYKCVASNPGGQ-----DSLLVKIQV----IAAPPVILEQRRQVIVGTWGES 1859
Query: 301 VMFDCTATGFPKPHVAWYF-NGERM----LLNERIILQHNGSILIKNVQNSDAGVYTCQV 355
+ CTA G P+P V W +G + N ++ L NG++ I+N+ +SD G Y C
Sbjct: 1860 LKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIA 1919
Query: 356 ENIHGKISASVPL---EVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWY--R 409
+ G V L E P +T + GD + C A G PKP I W
Sbjct: 1920 TSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPS 1979
Query: 410 NTVI--LPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
V+ G+ + N +L + VT D +Y C A N G +L + +
Sbjct: 1980 KAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG---DDLILMHVSLRLK 2036
Query: 468 PPRIVLKPE-DMDAFKETSVQMPCEIESVPPASIDWR-KDGSRI----VEDD------RI 515
P +I K Q+ C+ P I W DG+ I DD R
Sbjct: 2037 PAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRY 2096
Query: 516 SITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ G+L V V + G Y C A N G+D V LTV
Sbjct: 2097 TLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTV 2136
Score = 95.5 bits (227), Expect = 1e-18
Identities = 74/288 (25%), Positives = 121/288 (42%), Gaps = 26/288 (9%)
Query: 180 QQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN---ENRYEIFDNG 235
++P F + N+ + G++ C G P PEI+W+ + N +Y I NG
Sbjct: 2335 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 2394
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+ ++ + D G + C A+N G K+++ ++ PV ++
Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIE----KLVILEIGQK------PVILTYAPGTVKG 2444
Query: 296 INETSVMFDCTATGFPKPHVAWYFNG----ERMLLNERIILQHNGSILIKNVQNSDAGVY 351
I+ S+ C + G PKP++ W +R +N + IL NG+++IK D G Y
Sbjct: 2445 ISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY 2504
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
C+ +N G +VP+ + A P I P + G C A G PKP I W
Sbjct: 2505 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM 2564
Query: 410 NTVILPITGNLVLSDDNQNL----TLL--EVTRDDDAIYHCRAENDGG 451
L T + + ++ L TL+ D IY C A+N G
Sbjct: 2565 PDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 2612
Score = 94.7 bits (225), Expect = 2e-18
Identities = 75/273 (27%), Positives = 125/273 (45%), Gaps = 22/273 (8%)
Query: 305 CTATGFPKPHVAWY-----FNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C A G P P + W + + N R+ + NG++ I+ V+ D G Y C N+
Sbjct: 1670 CEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLF 1729
Query: 360 GKISASVPLEVTA-PPSFIVVPTNQ-TAIIGDNVWFTCKAKGTPKPSIKWY--RNTVILP 415
G V L V + PP + T + T G V C+A+G P P++ W TV+
Sbjct: 1730 GTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSE 1789
Query: 416 I---TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ V++ D L L ++ D Y C A N GG ++L QV PP I+
Sbjct: 1790 SSQGSRQAVVTVDG-TLVLHNLSIYDRGFYKCVASNPGGQ---DSLLVKIQVIAAPPVIL 1845
Query: 473 -LKPEDMDAFKETSVQMPCEIESVPPASIDW-RKDGSRI----VEDDRISITVIGSLIIR 526
+ + + S+++PC + P S+ W DG+ + + ++ + G+L IR
Sbjct: 1846 EQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIR 1905
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
N++ +D G YEC A + G + V LT+++ +
Sbjct: 1906 NLASSDRGTYECIATSSTGSERRVVMLTMEERV 1938
Score = 63.7 bits (148), Expect = 4e-09
Identities = 42/139 (30%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I I F+ L L+ L ++ N +R L+ F+G I+ I+ +VF
Sbjct: 91 NGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGLRSLTRLHMDHNNIEFINPEVFY 150
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLDR--------LYLHNNKLKSIPYGSFQGMPK 122
L L ++L N++ + P+TF +L L LYL +N L S+P MP
Sbjct: 151 GLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKISFIKFLYLSDNFLTSLPQEMVSYMPD 210
Query: 123 LRKLRLDSNALICDCSILW 141
L L L N CDC + W
Sbjct: 211 LDSLYLHGNPWTCDCHLKW 229
Score = 59.7 bits (138), Expect = 7e-08
Identities = 47/183 (25%), Positives = 77/183 (42%), Gaps = 15/183 (8%)
Query: 384 TAIIGDNVWFTCKAKGTPKPSIKWYR---NTVILPITGN--LVLSDDNQNLTLLEVTRDD 438
T ++G V C +G P P + W + V P +L D + L L D
Sbjct: 486 TVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFD 545
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPED---MDAFKETSVQMPCEIESV 495
+YHC + N + + +LT ++ ++ P + E+ F ++ +PC +
Sbjct: 546 TGVYHCISSN----YDDADILTY-RITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGI 600
Query: 496 PPASIDWRKDGSRIVEDDRISITVI--GSLIIRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P ASI W G+ ++ V+ G+L I V+ D G Y C A N G D +
Sbjct: 601 PDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSGVDFLIFQV 660
Query: 554 TVK 556
+VK
Sbjct: 661 SVK 663
Score = 57.2 bits (132), Expect = 4e-07
Identities = 44/164 (26%), Positives = 71/164 (43%), Gaps = 13/164 (7%)
Query: 300 SVMFDCTATGFPKPHVAWYF-NGERM---LLNE--RIILQHNGSILIKNVQNSDAGVYTC 353
+V +C G P PHV W +G ++ ++E RI++ +G + ++ + D GVY C
Sbjct: 492 TVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVYHC 551
Query: 354 QVENIHGKISASVPLEVTAP--PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWY--- 408
N + + V P ++ + T IG+ + C + G P SI W
Sbjct: 552 ISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVIPG 611
Query: 409 RNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGM 452
N + VL +N L +L+VT D Y C A N G+
Sbjct: 612 NNVLYQSSRDKKVL--NNGTLRILQVTPKDQGYYRCVAANPSGV 653
Score = 48.8 bits (111), Expect = 1e-04
Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 61 IKHIDSDVFQDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGM 120
++ +++D F L LE L LH N IH I +TFS+L L L + NK++ + +F G+
Sbjct: 70 VRLMETD-FSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTFYGL 128
Query: 121 PKLRKLRLDSN 131
L +L +D N
Sbjct: 129 RSLTRLHMDHN 139
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 11/86 (12%)
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRK-----DGSRIVEDDRISITVIGSLIIRNVS 529
P + DAF +PCE P +I W + D S+ ++ R+ + G+L I+ V
Sbjct: 1661 PANSDAF------LPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVE 1714
Query: 530 VTDTGRYECSAFNDYGRDTASVFLTV 555
+ D G+Y CSA N +G D V L+V
Sbjct: 1715 IQDRGQYLCSASNLFGTDHLHVTLSV 1740
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/102 (28%), Positives = 45/102 (44%)
Query: 32 LNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQDLKHLEQLYLHVNEIHHIEPE 91
L N L L F G I I F DL+ L+ L + N++ ++ +
Sbjct: 64 LGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKD 123
Query: 92 TFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDSNAL 133
TF L L RL++ +N ++ I F G+ LR + L+ N L
Sbjct: 124 TFYGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQL 165
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/119 (21%), Positives = 51/119 (42%)
Query: 10 FNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVF 69
+N + + F+ L +L L+L+ N + + F ++ + D F
Sbjct: 66 YNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYNKVRKLQKDTF 125
Query: 70 QDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRL 128
L+ L +L++ N I I PE F L L ++L N+L + +F + L+ ++
Sbjct: 126 YGLRSLTRLHMDHNNIEFINPEVFYGLNFLRLVHLEGNQLTKLHPDTFVSLSYLQIFKI 184
Score = 40.7 bits (91), Expect = 0.034
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Query: 193 VSFGENAVFTCVATGEPAPEILW-LRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFE 251
V GE C +TG P I W + + V+ + ++ +NGTL + + D G +
Sbjct: 585 VFIGETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYR 644
Query: 252 CMAKNVAG 259
C+A N +G
Sbjct: 645 CVAANPSG 652
Score = 35.9 bits (79), Expect = 0.97
Identities = 17/58 (29%), Positives = 33/58 (56%)
Query: 74 HLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLDSN 131
++E++ L N + + FS L +L+ L LH+N + +IP +F + L+ L++ N
Sbjct: 58 NVERINLGYNSLVRLMETDFSGLTKLELLMLHSNGIHTIPDKTFSDLQALQVLKMSYN 115
Score = 34.7 bits (76), Expect = 2.2
Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query: 485 SVQMPCEIESVPPASIDWR-KDGSRI-----VEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+V + C + P +DW DGS++ ED RI I G L ++ DTG Y C
Sbjct: 492 TVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVYHC 551
Query: 539 SAFNDYGRDTASVFLTVKDNLL 560
+ N D + +TV + L+
Sbjct: 552 ISSNYDDADILTYRITVVEPLV 573
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 138 bits (334), Expect = 1e-31
Identities = 114/391 (29%), Positives = 173/391 (44%), Gaps = 38/391 (9%)
Query: 192 EVSFGENAVFTCVATGEPAPEILW-LRDSEVIPL---------NENRYEIFDNGTLMVHE 241
+V G++ C A+G P PEI W L D +I RY +F+NGTL ++
Sbjct: 76 QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNK 135
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++G + C A+N GK K ++ + AP + S + K +T+V
Sbjct: 136 VGVAEEGDYTCYAQNTLGKDEMKVHLTVI--------TAAPRIRQSNKTNKRIKAGDTAV 187
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ DC TG PKP + W M+ +R NGS+ I V+ D+G Y C N
Sbjct: 188 L-DCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPS 246
Query: 360 GKISASVPLEVTA-PPSFIVVPTNQTAIIGDNV-----WFTCKAKGTPKPSIKWYR-NTV 412
G + L+V + PP + TN+T I V F C+A+GTP P + W + +
Sbjct: 247 GDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNI 306
Query: 413 IL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
L P G+ + N L + V D A + C A N+GG E+ V+ LE +E++
Sbjct: 307 FLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGG--ESVLVVQLEVLEMLRRP 364
Query: 471 IVLKP--EDMDAFKETSVQMPCEIESVPPASIDW-RKDGSRI---VEDDRISITVIGSLI 524
P E + A S + C ++ PP I W +G+R + + I GS I
Sbjct: 365 TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI 424
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
I + D G+Y C+A N G V L +
Sbjct: 425 ISKTTREDAGKYRCAARNKVGYIEKLVILEI 455
Score = 134 bits (323), Expect = 3e-30
Identities = 103/384 (26%), Positives = 164/384 (42%), Gaps = 26/384 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLMVHEAN 243
+S + + G+ AV C TG+P P+I WL S ++I + +RY NG+L +++
Sbjct: 172 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 231
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
D G + C+A+N +G +K K+ V K ++ + + + + F
Sbjct: 232 LLDSGEYVCVARNPSGD-DTKMYKLDVVSKPPLING----LYTNRTVIKATAVRHSKKHF 286
Query: 304 DCTATGFPKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
DC A G P P V W L RI + NG++ I+NV+ SD+ + C N
Sbjct: 287 DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEG 346
Query: 360 GKISASVPLEV---TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
G+ V LEV P+F P N+ A +G + C G P P I W
Sbjct: 347 GESVLVVQLEVLEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTR 405
Query: 415 PITG---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
G L N + + + TR+D Y C A N G IE +L + Q +I +
Sbjct: 406 FSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVI---L 462
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI----GSLIIRN 527
P + S+ + C + +P +I W +V+ +I+ I G+L+I+
Sbjct: 463 TYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKE 522
Query: 528 VSVTDTGRYECSAFNDYGRDTASV 551
+ D G Y C A N G +V
Sbjct: 523 ATAYDRGNYICKAQNSVGHTLITV 546
Score = 132 bits (319), Expect = 8e-30
Identities = 102/375 (27%), Positives = 164/375 (43%), Gaps = 31/375 (8%)
Query: 201 FTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNV 257
F C A G P+PE++W+ + P +R + NGTL + +D F C+A+N
Sbjct: 286 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 345
Query: 258 AGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW 317
G++ ++V+ + E P F + ++ S +C+ G P P + W
Sbjct: 346 GGES-----VLVVQLEVLEMLRR--PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 398
Query: 318 YF-NGERML---LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
NG R + + ++ NGS +I DAG Y C N G I V LE+
Sbjct: 399 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 458
Query: 374 PSFIV-VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT---VILP-ITGNLVLSDDNQN 428
P + P I G+++ C + G PKP+IKW + V P I G +L D N
Sbjct: 459 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGT 517
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQ 487
L + E T D Y C+A+N G + + + PPRI +P + + Q
Sbjct: 518 LVIKEATAYDRGNYICKAQNSVGH---TLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQ 574
Query: 488 MPCEIESVPPASIDWRKDGSRIVED---DRI----SITVIGSLIIRNVSVTDTGRYECSA 540
+ C VP I W ++ +R + + G+L+I+N +D+G Y+C+A
Sbjct: 575 LHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTA 634
Query: 541 FNDYGRDTASVFLTV 555
N G D A+ ++ V
Sbjct: 635 KNPLGSDYAATYIQV 649
Score = 95.5 bits (227), Expect = 1e-18
Identities = 74/288 (25%), Positives = 121/288 (42%), Gaps = 26/288 (9%)
Query: 180 QQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN---ENRYEIFDNG 235
++P F + N+ + G++ C G P PEI+W+ + N +Y I NG
Sbjct: 362 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 421
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+ ++ + D G + C A+N G K+++ ++ PV ++
Sbjct: 422 SFIISKTTREDAGKYRCAARNKVGYIE----KLVILEIGQK------PVILTYAPGTVKG 471
Query: 296 INETSVMFDCTATGFPKPHVAWYFNG----ERMLLNERIILQHNGSILIKNVQNSDAGVY 351
I+ S+ C + G PKP++ W +R +N + IL NG+++IK D G Y
Sbjct: 472 ISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY 531
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
C+ +N G +VP+ + A P I P + G C A G PKP I W
Sbjct: 532 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM 591
Query: 410 NTVILPITGNLVLSDDNQNL----TLL--EVTRDDDAIYHCRAENDGG 451
L T + + ++ L TL+ D IY C A+N G
Sbjct: 592 PDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 639
Score = 89.0 bits (211), Expect = 1e-16
Identities = 92/352 (26%), Positives = 143/352 (40%), Gaps = 35/352 (9%)
Query: 231 IFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQ 290
++ NG+L + E D G++ C+A+N G M V + + K F
Sbjct: 22 VYPNGSLFIGSVTEKDSGVYLCVARNKMG---DDLILMHVSLRLKPAKIDHKQYF----- 73
Query: 291 KRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLN-----------ERIILQHNGSIL 339
R ++ DC A+G P P ++W M+ N R L +NG++
Sbjct: 74 -RKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLY 132
Query: 340 IKNVQNSDAGVYTCQVENIHGKISASVPLEV-TAPPSFIVV-PTNQTAIIGDNVWFTCKA 397
V ++ G YTC +N GK V L V TA P TN+ GD C+
Sbjct: 133 FNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEV 192
Query: 398 KGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS 456
G PKP I W + ++ + + N +LT+ +V D Y C A N G + +
Sbjct: 193 TGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSG--DDT 250
Query: 457 AVLTLEQVEIIPPRIVLKPEDMDAFKETSVQ-----MPCEIESVPPASIDWRKDGSRIVE 511
+ L+ V PP I + K T+V+ C E P + W + +
Sbjct: 251 KMYKLDVVSK-PPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLT 309
Query: 512 ----DDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
RI++ G+L IRNV ++D+ + C A N+ G V L V + L
Sbjct: 310 APYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEML 361
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 138 bits (333), Expect = 2e-31
Identities = 100/377 (26%), Positives = 165/377 (43%), Gaps = 23/377 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E ++ E G C+A G P P I W ++ ++P N Y+ F+ TL + +E
Sbjct: 274 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-TLQIIHVSE 332
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G ++C+AKN G H + VR K A P +++ PQ E +
Sbjct: 333 ADSGNYQCIAKNALGAIHH---TISVRVK-------AAPYWITAPQNLVLSPGEDGTLI- 381
Query: 305 CTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A G PKP ++W NG + + ++ +I+ NVQ + VY C N +G +
Sbjct: 382 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 441
Query: 363 SASVPLEVTAPPSFIVVPTN--QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
A+ + V A P I+ P N I C G+P P+I+W++ + ++
Sbjct: 442 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI 501
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ +N L + +D Y C A N GM + L ++ P IV +PE
Sbjct: 502 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD----PTWIVKQPEYAVV 557
Query: 481 FKETSVQMPCEIESVPPASID--WRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + V C+++ S+ W KD + D+R ++ L++ +VS D+G Y C
Sbjct: 558 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK-DHLVVADVSDDDSGTYTC 616
Query: 539 SAFNDYGRDTASVFLTV 555
A +AS L+V
Sbjct: 617 VANTTLDSVSASAVLSV 633
Score = 104 bits (249), Expect = 2e-21
Identities = 78/283 (27%), Positives = 117/283 (41%), Gaps = 12/283 (4%)
Query: 282 PPVFVSTPQKRFAKINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI 338
PP F+ TP+ + E + +C A G P P + W + N + ++
Sbjct: 267 PPTFL-TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 325
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK 398
I +V +D+G Y C +N G I ++ + V A P +I P N G++ C+A
Sbjct: 326 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 385
Query: 399 GTPKPSIKWYRNTVILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
G PKP I W N V + I + D + V A+Y C A N+ G + A+A
Sbjct: 386 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 445
Query: 458 VLTLEQVEIIPPRIVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDR 514
+ V PPRI+ + + C P +I+W K GS + ED
Sbjct: 446 FV---NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 502
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ + G+L I TG Y C A N G V L +KD
Sbjct: 503 V-LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD 544
Score = 103 bits (248), Expect = 3e-21
Identities = 78/286 (27%), Positives = 118/286 (41%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS---EVIPLNENRYEIFDNGTLM 238
P + + P ++ +S GE+ C A G P P I WL + E+ P + +R D T++
Sbjct: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK--IDGDTII 418
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
E +++C A N G A V AE PP ++ + I
Sbjct: 419 FSNVQERSSAVYQCNASNEYGYLL---ANAFVNVLAE------PPRILTPANTLYQVIAN 469
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVEN 357
+ DC G P P + W+ + L+E I +L NG++ I Q G YTC N
Sbjct: 470 RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 529
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK--GTPKPSIKWYRNTVILP 415
G V LE+ P + P G V F CK K T ++ W ++ LP
Sbjct: 530 KLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 589
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+ D +L + +V+ DD Y C A + ASAVL++
Sbjct: 590 SDERFTV--DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
Score = 67.7 bits (158), Expect = 3e-10
Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 472 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS-VMFDCTA--TGFPKPHV 315
G A K E H P ++ Q +A + S V F+C V
Sbjct: 532 GMA-----------KNEVHLEIKDPTWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 579
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
W + + +ER + + +++ +V + D+G YTC +SAS L V AP
Sbjct: 580 LWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 50 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 109
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 110 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 161
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 162 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 356 ENIHGK-ISASVPLEV 370
H + I P+ V
Sbjct: 221 RFNHTQTIQQKQPISV 236
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 389 DNVWFTCKAKGTPKPSIKWYRNTVILPITGN-LVLSDDNQNLTLLEVTRDDDA-----IY 442
+N+ C+AKG P PS W RN I + LV ++ + + A +Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 443 HCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIE-SVPPASID 501
C A N+ G ++ ++ + + L+P + + + S+ +PC +PP I
Sbjct: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ--SLVLPCRPPIGLPPPIIF 179
Query: 502 WRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGR-YECSA-FN 542
W + R+ + +R+S + G L NV DT Y C A FN
Sbjct: 180 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 223
Score = 43.6 bits (98), Expect = 0.005
Identities = 72/317 (22%), Positives = 114/317 (35%), Gaps = 45/317 (14%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNL----TLLEVTRDDDAIY-- 442
++ C+ G P P I W N+ V N +L L E TR+D Y
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
Query: 443 --HCRAENDGGMIEASAVLTLEQVEIIP-----------------PRIVLKPEDMDAFKE 483
H + I + E + I P L PE + KE
Sbjct: 222 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 281
Query: 484 ----TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+ + C E +P I W K+ + ++ + +L I +VS D+G Y+C
Sbjct: 282 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 341
Query: 540 AFNDYGRDTASVFLTVK 556
A N G ++ + VK
Sbjct: 342 AKNALGAIHHTISVRVK 358
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 138 bits (333), Expect = 2e-31
Identities = 100/377 (26%), Positives = 165/377 (43%), Gaps = 23/377 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E ++ E G C+A G P P I W ++ ++P N Y+ F+ TL + +E
Sbjct: 274 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-TLQIIHVSE 332
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G ++C+AKN G H + VR K A P +++ PQ E +
Sbjct: 333 ADSGNYQCIAKNALGAIHH---TISVRVK-------AAPYWITAPQNLVLSPGEDGTLI- 381
Query: 305 CTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A G PKP ++W NG + + ++ +I+ NVQ + VY C N +G +
Sbjct: 382 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 441
Query: 363 SASVPLEVTAPPSFIVVPTN--QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
A+ + V A P I+ P N I C G+P P+I+W++ + ++
Sbjct: 442 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI 501
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ +N L + +D Y C A N GM + L ++ P IV +PE
Sbjct: 502 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD----PTWIVKQPEYAVV 557
Query: 481 FKETSVQMPCEIESVPPASID--WRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + V C+++ S+ W KD + D+R ++ L++ +VS D+G Y C
Sbjct: 558 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK-DHLVVADVSDDDSGTYTC 616
Query: 539 SAFNDYGRDTASVFLTV 555
A +AS L+V
Sbjct: 617 VANTTLDSVSASAVLSV 633
Score = 104 bits (249), Expect = 2e-21
Identities = 78/283 (27%), Positives = 117/283 (41%), Gaps = 12/283 (4%)
Query: 282 PPVFVSTPQKRFAKINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI 338
PP F+ TP+ + E + +C A G P P + W + N + ++
Sbjct: 267 PPTFL-TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 325
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK 398
I +V +D+G Y C +N G I ++ + V A P +I P N G++ C+A
Sbjct: 326 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 385
Query: 399 GTPKPSIKWYRNTVILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
G PKP I W N V + I + D + V A+Y C A N+ G + A+A
Sbjct: 386 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 445
Query: 458 VLTLEQVEIIPPRIVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDR 514
+ V PPRI+ + + C P +I+W K GS + ED
Sbjct: 446 FV---NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 502
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ + G+L I TG Y C A N G V L +KD
Sbjct: 503 V-LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD 544
Score = 103 bits (248), Expect = 3e-21
Identities = 78/286 (27%), Positives = 118/286 (41%), Gaps = 19/286 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS---EVIPLNENRYEIFDNGTLM 238
P + + P ++ +S GE+ C A G P P I WL + E+ P + +R D T++
Sbjct: 361 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK--IDGDTII 418
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
E +++C A N G A V AE PP ++ + I
Sbjct: 419 FSNVQERSSAVYQCNASNEYGYLL---ANAFVNVLAE------PPRILTPANTLYQVIAN 469
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVEN 357
+ DC G P P + W+ + L+E I +L NG++ I Q G YTC N
Sbjct: 470 RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 529
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK--GTPKPSIKWYRNTVILP 415
G V LE+ P + P G V F CK K T ++ W ++ LP
Sbjct: 530 KLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 589
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+ D +L + +V+ DD Y C A + ASAVL++
Sbjct: 590 SDERFTV--DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 633
Score = 67.7 bits (158), Expect = 3e-10
Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 472 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 531
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS-VMFDCTA--TGFPKPHV 315
G A K E H P ++ Q +A + S V F+C V
Sbjct: 532 GMA-----------KNEVHLEIKDPTWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 579
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
W + + +ER + + +++ +V + D+G YTC +SAS L V AP
Sbjct: 580 LWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 50 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 109
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 110 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 161
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 162 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 356 ENIHGK-ISASVPLEV 370
H + I P+ V
Sbjct: 221 RFNHTQTIQQKQPISV 236
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/164 (26%), Positives = 72/164 (43%), Gaps = 12/164 (7%)
Query: 389 DNVWFTCKAKGTPKPSIKWYRNTVILPITGN-LVLSDDNQNLTLLEVTRDDDA-----IY 442
+N+ C+AKG P PS W RN I + LV ++ + + A +Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 443 HCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIE-SVPPASID 501
C A N+ G ++ ++ + + L+P + + + S+ +PC +PP I
Sbjct: 122 QCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ--SLVLPCRPPIGLPPPIIF 179
Query: 502 WRKDG-SRIVEDDRISITVIGSLIIRNVSVTDTGR-YECSA-FN 542
W + R+ + +R+S + G L NV DT Y C A FN
Sbjct: 180 WMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFN 223
Score = 43.6 bits (98), Expect = 0.005
Identities = 72/317 (22%), Positives = 114/317 (35%), Gaps = 45/317 (14%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNL----TLLEVTRDDDAIY-- 442
++ C+ G P P I W N+ V N +L L E TR+D Y
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
Query: 443 --HCRAENDGGMIEASAVLTLEQVEIIP-----------------PRIVLKPEDMDAFKE 483
H + I + E + I P L PE + KE
Sbjct: 222 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 281
Query: 484 ----TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+ + C E +P I W K+ + ++ + +L I +VS D+G Y+C
Sbjct: 282 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 341
Query: 540 AFNDYGRDTASVFLTVK 556
A N G ++ + VK
Sbjct: 342 AKNALGAIHHTISVRVK 358
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 137 bits (331), Expect = 3e-31
Identities = 109/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-TLEQVEIIPPRIVLKPEDMDA 480
+ N L + V D Y C + G IEA AVL LE+++ PP +P+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLEKLKFTPPP---QPQQCMG 515
Query: 481 F-KETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
F KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (263), Expect = 5e-23
Identities = 107/379 (28%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A L+V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMGFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (263), Expect = 5e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQAVLQVL----EKLKFTPPP----QPQQCMGFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 100 bits (240), Expect = 3e-20
Identities = 97/384 (25%), Positives = 150/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVKLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + +A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFSQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A L V + L
Sbjct: 479 YRCMSSTPAGSIEAQAVLQVLEKL 502
Score = 78.2 bits (184), Expect = 2e-13
Identities = 88/388 (22%), Positives = 150/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 E--NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DPLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 KLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 SQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 68.5 bits (160), Expect = 1e-10
Identities = 62/270 (22%), Positives = 109/270 (40%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 PLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFSQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>BC114938-1|AAI14939.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 136 bits (330), Expect = 4e-31
Identities = 127/430 (29%), Positives = 202/430 (46%), Gaps = 37/430 (8%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 163 RDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFP-RDSQNPLLMWAAPDP 221
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 222 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 280
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS+ F A+ +F +++ P
Sbjct: 281 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPP 336
Query: 1020 VLHRYDEN--FETIPQGH------LLLRNAFFSPWR--LVDEGGVDPLLRGMFTTPAKLK 1069
++ + + F+ + + L + N+++S L VD LL GM + A+ +
Sbjct: 337 GVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE 396
Query: 1070 TSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLS 1129
L ++ + D A +QRGRD +P YTK R +S + + D++
Sbjct: 397 DHV--LVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDIN 454
Query: 1130 GEISDKEVRDKLQELYGSVHNIDV-WV----GGILEDQVEGGKVGPLFRCLLMEQFVRLR 1184
+S D + E +++N D+ W+ GG+LE + G PLF +++EQFVRLR
Sbjct: 455 PALSRSN--DTVLEATAALYNQDLSWLELLPGGLLESHRDPG---PLFSTIVLEQFVRLR 509
Query: 1185 DGDRFWYENP--SVFKPDQLRQIKETSLARILCDNGDNID--TISENVFYL----PEVQD 1236
DGDR+W+EN +F ++ +I+ T+L +L NID + NVF P Q
Sbjct: 510 DGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLV-AVINIDPSALQPNVFVWHKGDPCPQP 568
Query: 1237 GLVSCEDLPS 1246
+S E LP+
Sbjct: 569 RQLSTEGLPA 578
>BC114628-1|AAI14629.1| 1551|Homo sapiens dual oxidase 1 protein.
Length = 1551
Score = 136 bits (330), Expect = 4e-31
Identities = 127/430 (29%), Positives = 202/430 (46%), Gaps = 37/430 (8%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 163 RDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFP-RDSQNPLLMWAAPDP 221
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 222 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 280
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS+ F A+ +F +++ P
Sbjct: 281 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPP 336
Query: 1020 VLHRYDEN--FETIPQGH------LLLRNAFFSPWR--LVDEGGVDPLLRGMFTTPAKLK 1069
++ + + F+ + + L + N+++S L VD LL GM + A+ +
Sbjct: 337 GVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE 396
Query: 1070 TSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLS 1129
L ++ + D A +QRGRD +P YTK R +S + + D++
Sbjct: 397 DHV--LVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDIN 454
Query: 1130 GEISDKEVRDKLQELYGSVHNIDV-WV----GGILEDQVEGGKVGPLFRCLLMEQFVRLR 1184
+S D + E +++N D+ W+ GG+LE + G PLF +++EQFVRLR
Sbjct: 455 PALSRSN--DTVLEATAALYNQDLSWLELLPGGLLESHRDPG---PLFSTIVLEQFVRLR 509
Query: 1185 DGDRFWYENP--SVFKPDQLRQIKETSLARILCDNGDNID--TISENVFYL----PEVQD 1236
DGDR+W+EN +F ++ +I+ T+L +L NID + NVF P Q
Sbjct: 510 DGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLV-AVINIDPSALQPNVFVWHKGDPCPQP 568
Query: 1237 GLVSCEDLPS 1246
+S E LP+
Sbjct: 569 RQLSTEGLPA 578
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 136 bits (330), Expect = 4e-31
Identities = 100/379 (26%), Positives = 165/379 (43%), Gaps = 23/379 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANE 244
E ++ E G C+A G P P I W ++ ++P N Y+ F+ TL + +E
Sbjct: 268 EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK-TLQIIHVSE 326
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
D G ++C+AKN G H + VR K A P +++ PQ E +
Sbjct: 327 ADSGNYQCIAKNALGAIHH---TISVRVK-------AAPYWITAPQNLVLSPGEDGTLI- 375
Query: 305 CTATGFPKPHVAWYFNGERMLL--NERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKI 362
C A G PKP ++W NG + + ++ +I+ NVQ + VY C N +G +
Sbjct: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
Query: 363 SASVPLEVTAPPSFIVVPTN--QTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNL 420
A+ + V A P I+ P N I C G+P P+I+W++ + ++
Sbjct: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDI 495
Query: 421 VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDA 480
+ +N L + +D Y C A N GM + L ++ IV +PE
Sbjct: 496 YVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDA----TWIVKQPEYAVV 551
Query: 481 FKETSVQMPCEIESVPPASID--WRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
+ + V C+++ S+ W KD + D+R ++ L++ +VS D+G Y C
Sbjct: 552 QRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK-DHLVVADVSDDDSGTYTC 610
Query: 539 SAFNDYGRDTASVFLTVKD 557
A +AS L+V D
Sbjct: 611 VANTTLDSVSASAVLSVVD 629
Score = 104 bits (249), Expect = 2e-21
Identities = 78/283 (27%), Positives = 117/283 (41%), Gaps = 12/283 (4%)
Query: 282 PPVFVSTPQKRFAKINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSI 338
PP F+ TP+ + E + +C A G P P + W + N + ++
Sbjct: 261 PPTFL-TPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTL 319
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK 398
I +V +D+G Y C +N G I ++ + V A P +I P N G++ C+A
Sbjct: 320 QIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRAN 379
Query: 399 GTPKPSIKWYRNTVILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
G PKP I W N V + I + D + V A+Y C A N+ G + A+A
Sbjct: 380 GNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANA 439
Query: 458 VLTLEQVEIIPPRIVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDR 514
+ V PPRI+ + + C P +I+W K GS + ED
Sbjct: 440 FV---NVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIY 496
Query: 515 ISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
+ + G+L I TG Y C A N G V L +KD
Sbjct: 497 V-LHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD 538
Score = 101 bits (242), Expect = 2e-20
Identities = 78/289 (26%), Positives = 118/289 (40%), Gaps = 19/289 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS---EVIPLNENRYEIFDNGTLM 238
P + + P ++ +S GE+ C A G P P I WL + E+ P + +R D T++
Sbjct: 355 PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK--IDGDTII 412
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
E +++C A N G A V AE PP ++ + I
Sbjct: 413 FSNVQERSSAVYQCNASNEYGYLL---ANAFVNVLAE------PPRILTPANTLYQVIAN 463
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERI-ILQHNGSILIKNVQNSDAGVYTCQVEN 357
+ DC G P P + W+ + L+E I +L NG++ I Q G YTC N
Sbjct: 464 RPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARN 523
Query: 358 IHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAK--GTPKPSIKWYRNTVILP 415
G V LE+ + P G V F CK K T ++ W ++ LP
Sbjct: 524 KLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELP 583
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ D +L + +V+ DD Y C A + ASAVL++ V
Sbjct: 584 SDERFTV--DKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDV 630
Score = 61.7 bits (143), Expect = 2e-08
Identities = 46/180 (25%), Positives = 78/180 (43%), Gaps = 16/180 (8%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 466 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 525
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS-VMFDCTA--TGFPKPHV 315
G A K E H ++ Q +A + S V F+C V
Sbjct: 526 GMA-----------KNEVHLEIKDATWI-VKQPEYAVVQRGSMVSFECKVKHDHTLSLTV 573
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPS 375
W + + +ER + + +++ +V + D+G YTC +SAS L V P+
Sbjct: 574 LWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
Score = 57.2 bits (132), Expect = 4e-07
Identities = 54/194 (27%), Positives = 88/194 (45%), Gaps = 16/194 (8%)
Query: 362 ISA-SVPLEVTAPPSFIVVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
ISA VPL++ PP+ I + + II +N+ C+AKG P PS W RN I
Sbjct: 27 ISALEVPLDLVQPPT-ITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDK 85
Query: 419 N-LVLSDDNQNLTLLEVTRDDDA-----IYHCRAENDGGMIEASAVLTLEQVEIIPPRIV 472
+ LV ++ + + A +Y C A N+ G ++ ++ + +
Sbjct: 86 DPLVTMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEK 145
Query: 473 LKPEDMDAFKETSVQMPCEIE-SVPPASIDWRKDG-SRIVEDDRISITVIGSLIIRNVSV 530
L+P + + + S+ +PC +PP I W + R+ + +R+S + G L NV
Sbjct: 146 LEPITLQSGQ--SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLP 203
Query: 531 TDTGR-YECSA-FN 542
DT Y C A FN
Sbjct: 204 EDTREDYICYARFN 217
Score = 52.4 bits (120), Expect = 1e-05
Identities = 48/196 (24%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 44 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 103
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 104 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 155
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 156 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 214
Query: 356 ENIHGK-ISASVPLEV 370
H + I P+ V
Sbjct: 215 RFNHTQTIQQKQPISV 230
Score = 43.6 bits (98), Expect = 0.005
Identities = 72/317 (22%), Positives = 114/317 (35%), Gaps = 45/317 (14%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 39 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 98
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 99 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 155
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNL----TLLEVTRDDDAIY-- 442
++ C+ G P P I W N+ V N +L L E TR+D Y
Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 215
Query: 443 --HCRAENDGGMIEASAVLTLEQVEIIP-----------------PRIVLKPEDMDAFKE 483
H + I + E + I P L PE + KE
Sbjct: 216 FNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKE 275
Query: 484 ----TSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECS 539
+ + C E +P I W K+ + ++ + +L I +VS D+G Y+C
Sbjct: 276 ELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCI 335
Query: 540 AFNDYGRDTASVFLTVK 556
A N G ++ + VK
Sbjct: 336 AKNALGAIHHTISVRVK 352
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 136 bits (330), Expect = 4e-31
Identities = 108/390 (27%), Positives = 168/390 (43%), Gaps = 32/390 (8%)
Query: 180 QQPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN----RYEIFDN 234
++PQ ++ P V V+ + VF C ATG+P P + W + S + N R+E+ N
Sbjct: 1851 EKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKN 1910
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
GTL++ + D G + C A N+ G +M+V + P + S Q
Sbjct: 1911 GTLVIRKVQVQDRGQYMCTASNLHGLD-----RMVVLLSVTVQQ---PQILASHYQDVTV 1962
Query: 295 KINETSVMFDCTATGFPKPHVAWYFNGERML-----LNERIILQHNGSILIKNVQNSDAG 349
+ +T M +C A G P P ++W F R+ + RI L N ++ IK SD G
Sbjct: 1963 YLGDTIAM-ECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRG 2021
Query: 350 VYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKW 407
VY C N G S ++ L V A P I + + G ++ C AK P PS++W
Sbjct: 2022 VYKCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRW 2081
Query: 408 Y--RNTVILP---ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
T I P + GNL + N L + + D Y C A N G + L ++
Sbjct: 2082 VLGDGTQIRPSQFLHGNLFVF-PNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQ 2140
Query: 463 QVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-----DDRISI 517
+ P D ++++ C P I WR R+++ D RI +
Sbjct: 2141 RAAANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKV 2200
Query: 518 TVIGSLIIRNVSVTDTGRYECSAFNDYGRD 547
G+L++++V+ D G Y C A N G D
Sbjct: 2201 FANGTLVVKSVTDKDAGDYLCVARNKVGDD 2230
Score = 128 bits (310), Expect = 1e-28
Identities = 110/396 (27%), Positives = 164/396 (41%), Gaps = 38/396 (9%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILW-LRDSEVIPL---------NENRYEIFDNGT 236
E ND +V +G + CVATG P PEI W L D ++ RY +F+NGT
Sbjct: 2249 EENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGT 2308
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L +E ++G + C A+N GK + +V A V Q + +
Sbjct: 2309 LYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAV-----QVPYGDV 2363
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQ 354
V C A G P P V W +++ +E+ + +G++LI+ Q SD+G YTC
Sbjct: 2364 ----VTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCL 2419
Query: 355 VENIHGKISASVPLEVTAPPSFI------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKW- 407
V N G+ +V + V P I + + A G CKA+G P P + W
Sbjct: 2420 VRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWA 2479
Query: 408 YRNTVILPIT--GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
+ V+LP GN + N +L + + + D C A N+GG EA ++ L +E
Sbjct: 2480 FPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGG--EARLIVQLTVLE 2537
Query: 466 IIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVED----DRISITV 519
+ I P E + A ++ + C P S+ W ++ R
Sbjct: 2538 PMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 2597
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
G L I +S D G Y C A N G V L V
Sbjct: 2598 DGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 2633
Score = 126 bits (305), Expect = 4e-28
Identities = 100/377 (26%), Positives = 160/377 (42%), Gaps = 24/377 (6%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLMVHEANENDDGL 249
V+V +G+ C A GEP P++ WL + +VIP + +Y+I+ +GTL++ +A +D G
Sbjct: 2356 VQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGN 2415
Query: 250 FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATG 309
+ C+ +N AG+ + + + K P ++T ++ A + + DC A G
Sbjct: 2416 YTCLVRNSAGEDRK---TVWIHVNVQPPKINGNPNPITTVREIAA--GGSRKLIDCKAEG 2470
Query: 310 FPKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
P P V W F +L RI + NGS+ I++++ SD+ C N G+
Sbjct: 2471 IPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLI 2530
Query: 366 VPLEVTAP---PSF-IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW-YRNTVILPITGNL 420
V L V P P F + TA+ G + C A GTP PS+ W N L L
Sbjct: 2531 VQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQL 2590
Query: 421 --VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + ++ D Y C A N G E L +V + P +
Sbjct: 2591 QRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSL---KVGLKPEANKQYHNLV 2647
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVED----DRISITVIGSLIIRNVSVTDTG 534
++++PC W +E R+S+ G+L +R SV D G
Sbjct: 2648 SIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRG 2707
Query: 535 RYECSAFNDYGRDTASV 551
Y C +YG S+
Sbjct: 2708 TYVCRMETEYGPSVTSI 2724
Score = 123 bits (297), Expect = 4e-27
Identities = 94/293 (32%), Positives = 136/293 (46%), Gaps = 23/293 (7%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW--YFNGERMLLNERII---LQHNG 336
P + +PQ + ET +F C ATG PKP V W G M N RI + NG
Sbjct: 1853 PQILTKSPQT-VSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNG 1911
Query: 337 SILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ--TAIIGDNVWFT 394
+++I+ VQ D G Y C N+HG V L VT I+ Q T +GD +
Sbjct: 1912 TLVIRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAME 1971
Query: 395 CKAKGTPKPSIKWY---RNT--VILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEND 449
C AKGTP P I W R + P+ + L + N+ L++ E + D +Y C A N
Sbjct: 1972 CLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHE-NRTLSIKEASFSDRGVYKCVASNA 2030
Query: 450 GGMIEASAVLTLEQVEIIPPRIVL-KPEDMDAFKETSVQMPCEIESVPPASIDW-RKDGS 507
G A ++ V +PP I K E++ S+ + C ++ P S+ W DG+
Sbjct: 2031 AG---ADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGT 2087
Query: 508 RIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+I + + G+L IRN++ D+GRYEC A N G +V L V+
Sbjct: 2088 QIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQ 2140
Score = 110 bits (265), Expect = 3e-23
Identities = 105/400 (26%), Positives = 165/400 (41%), Gaps = 34/400 (8%)
Query: 180 QQPQFESEPNDV----EVSFG-ENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEI 231
Q P+ PN + E++ G + C A G P P +LW V+ P NR +
Sbjct: 2438 QPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV 2497
Query: 232 FDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQK 291
NG+L + ++D CMA+N G+A ++IV+ E P+F +
Sbjct: 2498 HGNGSLDIRSLRKSDSVQLVCMARNEGGEA-----RLIVQLTVLEPMEK--PIFHDPISE 2550
Query: 292 RFAKINETSVMFDCTATGFPKPHVAWYF-NGERMLLNE---RIILQHNGSILIKNVQNSD 347
+ + ++ +C+A G P P + W NG + + R + +G + I + + D
Sbjct: 2551 KITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 2610
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII-GDNVWFTCKAKGTPKPSIK 406
AG Y C N G V L+V P N +II G+ + C G +
Sbjct: 2611 AGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFS 2670
Query: 407 W-YRNTVIL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
W N + L P T V DN LT+ E + D Y CR E + G S +
Sbjct: 2671 WTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVI--- 2727
Query: 464 VEIIPPRIVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWR-------KDGSRIVEDDRI 515
V PPRI +P + + +V++ C +P A I W K G +
Sbjct: 2728 VIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNR 2787
Query: 516 SITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ GSL I++ + D G Y+C A N G D+ + ++ V
Sbjct: 2788 FLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
Score = 110 bits (264), Expect = 4e-23
Identities = 97/422 (22%), Positives = 184/422 (43%), Gaps = 42/422 (9%)
Query: 162 ASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILW-LRD-S 219
++ G A++ H + + ++ + G + C A P P + W L D +
Sbjct: 2028 SNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVLGDGT 2087
Query: 220 EVIP---LNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEE 276
++ P L+ N + +F NGTL + D G +EC+A N+ G A + ++ V+R A
Sbjct: 2088 QIRPSQFLHGNLF-VFPNGTLYIRNLAPKDSGRYECVAANLVGSAR-RTVQLNVQRAAAN 2145
Query: 277 HKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERML-----LNERII 331
+ + ++P++ + T + DC+A+G P P + W +RM+ + RI
Sbjct: 2146 AR-----ITGTSPRRTDVRYGGT-LKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIK 2199
Query: 332 LQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFI--VVPTNQTAIIGD 389
+ NG++++K+V + DAG Y C N G + ++V P+ I + G
Sbjct: 2200 VFANGTLVVKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDHKVFYGG 2259
Query: 390 NVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEND 449
++ C A G P P I W + + + + SDD+ T V ++ +Y N+
Sbjct: 2260 DLKVDCVATGLPNPEISW--SLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYF----NE 2313
Query: 450 GGMIEASAVLTLEQVEI------IPPRIVLKPEDMDAFKETSVQMP--------CEIESV 495
GM E + ++ + ++V P + +VQ+P CE +
Sbjct: 2314 VGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGE 2373
Query: 496 PPASIDWRKDGSRIV--EDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P + W ++++ ++ I G+L+I+ +D+G Y C N G D +V++
Sbjct: 2374 PMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTVWI 2433
Query: 554 TV 555
V
Sbjct: 2434 HV 2435
Score = 76.2 bits (179), Expect = 7e-13
Identities = 72/288 (25%), Positives = 117/288 (40%), Gaps = 28/288 (9%)
Query: 178 PCQQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF---D 233
P ++P F ++ + G C A G P P ++W+ + + + + F
Sbjct: 2538 PMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 2597
Query: 234 NGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRF 293
+G L + + D G + C+A+N AG + + V K E +K V +
Sbjct: 2598 DGMLHISGLSSVDAGAYRCVARNAAGHTE-RLVSLKVGLKPEANKQYHNLVSI------- 2649
Query: 294 AKINETSVMFDCTATGFPKPHVAWYF-NGERMLLNE---RIILQHNGSILIKNVQNSDAG 349
IN ++ CT G + +W NG + + R+ L NG++ ++ D G
Sbjct: 2650 --INGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRG 2707
Query: 350 VYTCQVENIHGKISASVPLEVTA-PPSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPSIKW 407
Y C++E +G S+P+ V A PP PT G+ V C A G PK I W
Sbjct: 2708 TYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 2767
Query: 408 -------YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
+ V + GN L +LT+ T+ D Y C A+N
Sbjct: 2768 ELPDKSHLKAGVQARLYGNRFLHPQG-SLTIQHATQRDAGFYKCMAKN 2814
Score = 67.7 bits (158), Expect = 3e-10
Identities = 51/196 (26%), Positives = 73/196 (37%), Gaps = 22/196 (11%)
Query: 11 NLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVFQ 70
N I I G L L+ + N LR + G I+ I F
Sbjct: 89 NEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFN 148
Query: 71 DLKHLEQLYLHVNEIHHIEPETFSNLPRLD--------RLYLHNNKLKSIPYGSFQGMPK 122
L L L+L N +H + P TFS LD LYL N ++++P + MP
Sbjct: 149 GLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLSTIRHLYLAENMVRTLPASMLRNMPL 208
Query: 123 LRKLRLDSNALICDCSILWFIRMLENN------------EWMHVAATCYQPASVTGTSLA 170
L L L N CDC + WF+ + E + A C+ P + +
Sbjct: 209 LENLYLQGNPWTCDCEMRWFLEWDAKSRGILKCKKDKAYEGGQLCAMCFSPKKLYKHEIH 268
Query: 171 AMKHHDLPCQQPQFES 186
+K D+ C +P ES
Sbjct: 269 KLK--DMTCLKPSIES 282
Score = 58.4 bits (135), Expect = 2e-07
Identities = 47/191 (24%), Positives = 85/191 (44%), Gaps = 18/191 (9%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILW-LRDSEVI--PLNE--NRYEIFDNGTLMVHEANE 244
D V G +C +P I W L D ++ P+++ +++ I +G L +
Sbjct: 488 DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEP 547
Query: 245 NDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
+D GL++C+A+ V + +++V+ + + PA V+ K SV
Sbjct: 548 SDSGLYQCIAQ-VRDEMDRMVYRVLVQSPSTQ---PAEKDTVT-----IGKNPGESVTLP 598
Query: 305 CTATGFPKPHVAWYFNGERMLLN----ERIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
C A P+ H++W R++ + + + NG++ I VQ SD+G Y C N G
Sbjct: 599 CNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
Query: 361 KISASVPLEVT 371
+V + VT
Sbjct: 659 ADHFTVGITVT 669
Score = 57.6 bits (133), Expect = 3e-07
Identities = 48/190 (25%), Positives = 80/190 (42%), Gaps = 19/190 (10%)
Query: 379 VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDD 438
V +QT + G +C K + PSI W +LP G+++ + + + +
Sbjct: 485 VQRDQTVLEGGPCQLSCNVKASESPSIFW-----VLP-DGSILKAPMDDPDSKFSILSSG 538
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKET---------SVQMP 489
+D G+ + A + E ++ +V P A K+T SV +P
Sbjct: 539 WLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLP 598
Query: 490 CEIESVPPASIDWRKDGSRIVED----DRISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
C ++P A + W RI+ D + + G+L I V V+D+G Y C A N G
Sbjct: 599 CNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
Query: 546 RDTASVFLTV 555
D +V +TV
Sbjct: 659 ADHFTVGITV 668
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 10 FNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVF 69
F + + G+ H+ ++ L N ++AL +F G I I
Sbjct: 43 FRSLASVPAGIARHVERIN---LGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGAL 99
Query: 70 QDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLD 129
+DL L+ N++ I +T L L RL++ +NK++ I +F G+ LR L L+
Sbjct: 100 RDLSSLQVFKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLE 159
Query: 130 SNAL 133
N L
Sbjct: 160 GNLL 163
Score = 49.6 bits (113), Expect = 7e-05
Identities = 31/121 (25%), Positives = 52/121 (42%)
Query: 10 FNLIQEIEPGVFNHLHQLRSLLLNDNHLRALRSGAFHGXXXXXXXXXXXXXIKHIDSDVF 69
FN IQ + F L +L L+++ N + ++ GA ++ I
Sbjct: 64 FNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQVFKFSYNKLRVITGQTL 123
Query: 70 QDLKHLEQLYLHVNEIHHIEPETFSNLPRLDRLYLHNNKLKSIPYGSFQGMPKLRKLRLD 129
Q L +L +L++ N+I I P+ F+ L L L+L N L + +F L RL
Sbjct: 124 QGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLHPSTFSTFTFLDYFRLS 183
Query: 130 S 130
+
Sbjct: 184 T 184
Score = 37.1 bits (82), Expect = 0.42
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 4/88 (4%)
Query: 178 PCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIP---LNENRYEIFDN 234
P QP E + + + GE+ C A P + W+ + I N + + N
Sbjct: 575 PSTQPA-EKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPN 633
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAH 262
GTL + + +D G + C+A N G H
Sbjct: 634 GTLSIPKVQVSDSGYYRCVAVNQQGADH 661
>AF230495-1|AAF73921.1| 1551|Homo sapiens NADPH thyroid oxidase 1
protein.
Length = 1551
Score = 136 bits (330), Expect = 4e-31
Identities = 127/430 (29%), Positives = 202/430 (46%), Gaps = 37/430 (8%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 163 RDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFP-RDSQNPLLMWAAPDP 221
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 222 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 280
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS+ F A+ +F +++ P
Sbjct: 281 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPP 336
Query: 1020 VLHRYDEN--FETIPQGH------LLLRNAFFSPWR--LVDEGGVDPLLRGMFTTPAKLK 1069
++ + + F+ + + L + N+++S L VD LL GM + A+ +
Sbjct: 337 GVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE 396
Query: 1070 TSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLS 1129
L ++ + D A +QRGRD +P YTK R +S + + D++
Sbjct: 397 DHV--LVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDIN 454
Query: 1130 GEISDKEVRDKLQELYGSVHNIDV-WV----GGILEDQVEGGKVGPLFRCLLMEQFVRLR 1184
+S D + E +++N D+ W+ GG+LE + G PLF +++EQFVRLR
Sbjct: 455 PALSRSN--DTVLEATAALYNQDLSWLELLPGGLLESHRDPG---PLFSTIVLEQFVRLR 509
Query: 1185 DGDRFWYENP--SVFKPDQLRQIKETSLARILCDNGDNID--TISENVFYL----PEVQD 1236
DGDR+W+EN +F ++ +I+ T+L +L NID + NVF P Q
Sbjct: 510 DGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLV-AVINIDPSALQPNVFVWHKGDPCPQP 568
Query: 1237 GLVSCEDLPS 1246
+S E LP+
Sbjct: 569 RQLSTEGLPA 578
>AF213465-1|AAF71295.1| 1551|Homo sapiens dual oxidase protein.
Length = 1551
Score = 136 bits (330), Expect = 4e-31
Identities = 127/430 (29%), Positives = 202/430 (46%), Gaps = 37/430 (8%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 163 RDPANQVTGWLDGSAIYGSSHSWSDALRSFSRGQLASGPDPAFP-RDSQNPLLMWAAPDP 221
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 222 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 280
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS+ F A+ +F +++ P
Sbjct: 281 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPP 336
Query: 1020 VLHRYDEN--FETIPQGH------LLLRNAFFSPWR--LVDEGGVDPLLRGMFTTPAKLK 1069
++ + + F+ + + L + N+++S L VD LL GM + A+ +
Sbjct: 337 GVYMRNASCHFQGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE 396
Query: 1070 TSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDLS 1129
L ++ + D A +QRGRD +P YTK R +S + + D++
Sbjct: 397 DHV--LVEDVRDFWPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDIN 454
Query: 1130 GEISDKEVRDKLQELYGSVHNIDV-WV----GGILEDQVEGGKVGPLFRCLLMEQFVRLR 1184
+S D + E +++N D+ W+ GG+LE + G PLF +++EQFVRLR
Sbjct: 455 PALSRSN--DTVLEATAALYNQDLSWLELLPGGLLESHRDPG---PLFSTIVLEQFVRLR 509
Query: 1185 DGDRFWYENP--SVFKPDQLRQIKETSLARILCDNGDNID--TISENVFYL----PEVQD 1236
DGDR+W+EN +F ++ +I+ T+L +L NID + NVF P Q
Sbjct: 510 DGDRYWFENTRNGLFSKKEIEEIRNTTLQDVLV-AVINIDPSALQPNVFVWHKGDPCPQP 568
Query: 1237 GLVSCEDLPS 1246
+S E LP+
Sbjct: 569 RQLSTEGLPA 578
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 136 bits (329), Expect = 5e-31
Identities = 113/391 (28%), Positives = 173/391 (44%), Gaps = 38/391 (9%)
Query: 192 EVSFGENAVFTCVATGEPAPEILW-LRDSEVIPL---------NENRYEIFDNGTLMVHE 241
+V G++ C A+G P PEI W L D +I RY +F+NGTL ++
Sbjct: 28 QVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNK 87
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
++G + C A+N GK K ++ + AP + S + K +T+V
Sbjct: 88 VGVAEEGDYTCYAQNTLGKDEMKVHLTVI--------TAAPRIRQSNKTNKRIKAGDTAV 139
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ DC TG PKP + W M+ +R NGS+ I V+ D+G Y C N
Sbjct: 140 L-DCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPS 198
Query: 360 GKISASVPLEVTA-PPSFIVVPTNQTAIIGDNV-----WFTCKAKGTPKPSIKWYR-NTV 412
G + L+V + PP + T++T I V F C+A+GTP P + W + +
Sbjct: 199 GDDTKMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNI 258
Query: 413 IL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
L P G+ + N L + V D A + C A N+GG E+ V+ LE +E++
Sbjct: 259 FLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGG--ESVLVVQLEVLEMLRRP 316
Query: 471 IVLKP--EDMDAFKETSVQMPCEIESVPPASIDW-RKDGSRI---VEDDRISITVIGSLI 524
P E + A S + C ++ PP I W +G+R + + I GS I
Sbjct: 317 TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI 376
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
I + D G+Y C+A N G V L +
Sbjct: 377 ISKTTREDAGKYRCAARNKVGYIEKLVILEI 407
Score = 135 bits (326), Expect = 1e-30
Identities = 104/384 (27%), Positives = 164/384 (42%), Gaps = 26/384 (6%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLMVHEAN 243
+S + + G+ AV C TG+P P+I WL S ++I + +RY NG+L +++
Sbjct: 124 QSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK 183
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
D G + C+A+N +G +K K+ V K ++ S + + + F
Sbjct: 184 LLDSGEYVCVARNPSGD-DTKMYKLDVVSKPPLING----LYTSRTVIKATAVRHSKKHF 238
Query: 304 DCTATGFPKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
DC A G P P V W L RI + NG++ I+NV+ SD+ + C N
Sbjct: 239 DCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEG 298
Query: 360 GKISASVPLEV---TAPPSFIVVPTNQ--TAIIGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
G+ V LEV P+F P N+ A +G + C G P P I W
Sbjct: 299 GESVLVVQLEVLEMLRRPTF-RNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTR 357
Query: 415 PITG---NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRI 471
G L N + + + TR+D Y C A N G IE +L + Q +I +
Sbjct: 358 FSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVI---L 414
Query: 472 VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVI----GSLIIRN 527
P + S+ + C + +P +I W +V+ +I+ I G+L+I+
Sbjct: 415 TYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKE 474
Query: 528 VSVTDTGRYECSAFNDYGRDTASV 551
+ D G Y C A N G +V
Sbjct: 475 ATAYDRGNYICKAQNSVGHTLITV 498
Score = 132 bits (319), Expect = 8e-30
Identities = 102/375 (27%), Positives = 164/375 (43%), Gaps = 31/375 (8%)
Query: 201 FTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNV 257
F C A G P+PE++W+ + P +R + NGTL + +D F C+A+N
Sbjct: 238 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 297
Query: 258 AGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW 317
G++ ++V+ + E P F + ++ S +C+ G P P + W
Sbjct: 298 GGES-----VLVVQLEVLEMLRR--PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 350
Query: 318 YF-NGERML---LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
NG R + + ++ NGS +I DAG Y C N G I V LE+
Sbjct: 351 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 410
Query: 374 PSFIV-VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT---VILP-ITGNLVLSDDNQN 428
P + P I G+++ C + G PKP+IKW + V P I G +L D N
Sbjct: 411 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGT 469
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQ 487
L + E T D Y C+A+N G + + + PPRI +P + + Q
Sbjct: 470 LVIKEATAYDRGNYICKAQNSVGH---TLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQ 526
Query: 488 MPCEIESVPPASIDWRKDGSRIVED---DRI----SITVIGSLIIRNVSVTDTGRYECSA 540
+ C VP I W ++ +R + + G+L+I+N +D+G Y+C+A
Sbjct: 527 LHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTA 586
Query: 541 FNDYGRDTASVFLTV 555
N G D A+ ++ V
Sbjct: 587 KNPLGSDYAATYIQV 601
Score = 95.5 bits (227), Expect = 1e-18
Identities = 74/288 (25%), Positives = 121/288 (42%), Gaps = 26/288 (9%)
Query: 180 QQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN---ENRYEIFDNG 235
++P F + N+ + G++ C G P PEI+W+ + N +Y I NG
Sbjct: 314 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 373
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+ ++ + D G + C A+N G K+++ ++ PV ++
Sbjct: 374 SFIISKTTREDAGKYRCAARNKVGYIE----KLVILEIGQK------PVILTYAPGTVKG 423
Query: 296 INETSVMFDCTATGFPKPHVAWYFNG----ERMLLNERIILQHNGSILIKNVQNSDAGVY 351
I+ S+ C + G PKP++ W +R +N + IL NG+++IK D G Y
Sbjct: 424 ISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY 483
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
C+ +N G +VP+ + A P I P + G C A G PKP I W
Sbjct: 484 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM 543
Query: 410 NTVILPITGNLVLSDDNQNL----TLL--EVTRDDDAIYHCRAENDGG 451
L T + + ++ L TL+ D IY C A+N G
Sbjct: 544 PDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 591
Score = 78.6 bits (185), Expect = 1e-13
Identities = 77/279 (27%), Positives = 115/279 (41%), Gaps = 26/279 (9%)
Query: 304 DCTATGFPKPHVAWYFNGERMLLN-----------ERIILQHNGSILIKNVQNSDAGVYT 352
DC A+G P P ++W M+ N R L +NG++ V ++ G YT
Sbjct: 38 DCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYT 97
Query: 353 CQVENIHGKISASVPLEV-TAPPSFIVV-PTNQTAIIGDNVWFTCKAKGTPKPSIKWYR- 409
C +N GK V L V TA P TN+ GD C+ G PKP I W
Sbjct: 98 CYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLP 157
Query: 410 NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPP 469
+ ++ + + N +LT+ +V D Y C A N G + + + L+ V PP
Sbjct: 158 SNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSG--DDTKMYKLDVVSK-PP 214
Query: 470 RIVLKPEDMDAFKETSVQ-----MPCEIESVPPASIDWRKDGSRIVE----DDRISITVI 520
I K T+V+ C E P + W + + RI++
Sbjct: 215 LINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKN 274
Query: 521 GSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNL 559
G+L IRNV ++D+ + C A N+ G V L V + L
Sbjct: 275 GTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEML 313
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 136 bits (328), Expect = 7e-31
Identities = 105/402 (26%), Positives = 172/402 (42%), Gaps = 25/402 (6%)
Query: 160 QPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS 219
QP SV S + + P E ++ E G C+A G P P I W ++
Sbjct: 232 QPISVKVISAKSSRERPPTFLTP--EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED 289
Query: 220 EVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKS 279
++P N Y+ F+ TL + +E D G ++C+AKN G H + VR KA
Sbjct: 290 GMLPKNRTVYKNFEK-TLQIIHVSEADSGNYQCIAKNALGAIHHT---ISVRVKAA---- 341
Query: 280 PAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGS 337
P +++ PQ E + C A G PKP ++W NG + + ++ +
Sbjct: 342 ---PYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 397
Query: 338 ILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQT--AIIGDNVWFTC 395
I+ NVQ + VY C N +G + A+ + V A P I+ P N I C
Sbjct: 398 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDC 457
Query: 396 KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G+P P+I+W++ + ++ + +N L + +D Y C A N GM +
Sbjct: 458 AFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKN 517
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASID--WRKDGSRIVEDD 513
L ++ I V +PE + + V C+++ S+ W KD + D+
Sbjct: 518 EVHLEIKDATWI----VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE 573
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
R ++ L++ +VS D+G Y C A +AS L+V
Sbjct: 574 RFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 614
Score = 113 bits (271), Expect = 5e-24
Identities = 96/390 (24%), Positives = 159/390 (40%), Gaps = 15/390 (3%)
Query: 178 PCQQPQFESEPND-VEVSFGENAVFTC-VATGEPAPEILWLRDS-EVIPLNENRYEIFDN 234
P + P + E + + + G++ V C G P P I W+ +S + +P +E + +
Sbjct: 141 PSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG 200
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
+ E+ + C A+ + + + V+ + + PP F+ TP+ +
Sbjct: 201 DLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL-TPEGNAS 259
Query: 295 KINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVY 351
E + +C A G P P + W + N + ++ I +V +D+G Y
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNY 319
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
C +N G I ++ + V A P +I P N G++ C+A G PKP I W N
Sbjct: 320 QCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379
Query: 412 VILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
V + I + D + V A+Y C A N+ G + A+A + V PPR
Sbjct: 380 VPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV---NVLAEPPR 436
Query: 471 IVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDRISITVIGSLIIRN 527
I+ + + C P +I+W K GS + ED + + G+L I
Sbjct: 437 ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPV 495
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
TG Y C A N G V L +KD
Sbjct: 496 AQKDSTGTYTCVARNKLGMAKNEVHLEIKD 525
Score = 99.1 bits (236), Expect = 9e-20
Identities = 95/395 (24%), Positives = 162/395 (41%), Gaps = 38/395 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 50 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 109
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 110 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 161
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 162 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 356 ENIHGK-ISASVPLEVTA---------PPSFIVV---PTNQTAIIGDNVWFTCKAKGTPK 402
H + I P+ V PP+F+ +N+ + G+ + C A+G P
Sbjct: 221 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 280
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P I W + +LP V + + L ++ V+ D Y C A+N G I + + ++
Sbjct: 281 PIIYWAKEDGMLP-KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 339
Query: 463 QVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIG 521
P + P+++ + C P I W +G I + D S + G
Sbjct: 340 AA----PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDG 395
Query: 522 -SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++I NV + Y+C+A N+YG A+ F+ V
Sbjct: 396 DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 430
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 10/175 (5%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 453 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
G A ++ + ++ K P V F E V D T + V W
Sbjct: 513 GMAKNE-VHLEIKDATWIVKQPEYAVVQRGSMVSF----ECKVKHDHTLS----LTVLWL 563
Query: 319 FNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
+ + +ER + + +++ +V + D+G YTC +SAS L V AP
Sbjct: 564 KDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 617
Score = 55.2 bits (127), Expect = 1e-06
Identities = 69/298 (23%), Positives = 114/298 (38%), Gaps = 26/298 (8%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD-AIYHCRAE 447
++ C+ G P P I W N+ V N +L V +D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
Query: 448 -NDGGMIEASAVLTLEQVEIIP----PRIVLKPEDMDAFKE----TSVQMPCEIESVPPA 498
N I+ ++++ + P L PE + KE + + C E +P
Sbjct: 222 FNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 281
Query: 499 SIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I W K+ + ++ + +L I +VS D+G Y+C A N G ++ + VK
Sbjct: 282 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 339
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 136 bits (328), Expect = 7e-31
Identities = 105/402 (26%), Positives = 172/402 (42%), Gaps = 25/402 (6%)
Query: 160 QPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS 219
QP SV S + + P E ++ E G C+A G P P I W ++
Sbjct: 232 QPISVKVISAKSSRERPPTFLTP--EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED 289
Query: 220 EVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKS 279
++P N Y+ F+ TL + +E D G ++C+AKN G H + VR KA
Sbjct: 290 GMLPKNRTVYKNFEK-TLQIIHVSEADSGNYQCIAKNALGAIHHT---ISVRVKAA---- 341
Query: 280 PAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGS 337
P +++ PQ E + C A G PKP ++W NG + + ++ +
Sbjct: 342 ---PYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 397
Query: 338 ILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQT--AIIGDNVWFTC 395
I+ NVQ + VY C N +G + A+ + V A P I+ P N I C
Sbjct: 398 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDC 457
Query: 396 KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G+P P+I+W++ + ++ + +N L + +D Y C A N GM +
Sbjct: 458 AFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKN 517
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASID--WRKDGSRIVEDD 513
L ++ I V +PE + + V C+++ S+ W KD + D+
Sbjct: 518 EVHLEIKDATWI----VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE 573
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
R ++ L++ +VS D+G Y C A +AS L+V
Sbjct: 574 RFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 614
Score = 113 bits (271), Expect = 5e-24
Identities = 96/390 (24%), Positives = 159/390 (40%), Gaps = 15/390 (3%)
Query: 178 PCQQPQFESEPND-VEVSFGENAVFTC-VATGEPAPEILWLRDS-EVIPLNENRYEIFDN 234
P + P + E + + + G++ V C G P P I W+ +S + +P +E + +
Sbjct: 141 PSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG 200
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
+ E+ + C A+ + + + V+ + + PP F+ TP+ +
Sbjct: 201 DLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL-TPEGNAS 259
Query: 295 KINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVY 351
E + +C A G P P + W + N + ++ I +V +D+G Y
Sbjct: 260 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNY 319
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
C +N G I ++ + V A P +I P N G++ C+A G PKP I W N
Sbjct: 320 QCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 379
Query: 412 VILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
V + I + D + V A+Y C A N+ G + A+A + V PPR
Sbjct: 380 VPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV---NVLAEPPR 436
Query: 471 IVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDRISITVIGSLIIRN 527
I+ + + C P +I+W K GS + ED + + G+L I
Sbjct: 437 ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPV 495
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
TG Y C A N G V L +KD
Sbjct: 496 AQKDSTGTYTCVARNKLGMAKNEVHLEIKD 525
Score = 99.1 bits (236), Expect = 9e-20
Identities = 95/395 (24%), Positives = 162/395 (41%), Gaps = 38/395 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 50 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 109
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 110 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 161
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 162 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 356 ENIHGK-ISASVPLEVTA---------PPSFIVV---PTNQTAIIGDNVWFTCKAKGTPK 402
H + I P+ V PP+F+ +N+ + G+ + C A+G P
Sbjct: 221 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 280
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P I W + +LP V + + L ++ V+ D Y C A+N G I + + ++
Sbjct: 281 PIIYWAKEDGMLP-KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 339
Query: 463 QVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIG 521
P + P+++ + C P I W +G I + D S + G
Sbjct: 340 AA----PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDG 395
Query: 522 -SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++I NV + Y+C+A N+YG A+ F+ V
Sbjct: 396 DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 430
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 10/175 (5%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 453 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 512
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
G A ++ + ++ K P V F E V D T + V W
Sbjct: 513 GMAKNE-VHLEIKDATWIVKQPEYAVVQRGSMVSF----ECKVKHDHTLS----LTVLWL 563
Query: 319 FNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
+ + +ER + + +++ +V + D+G YTC +SAS L V AP
Sbjct: 564 KDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 617
Score = 55.2 bits (127), Expect = 1e-06
Identities = 69/298 (23%), Positives = 114/298 (38%), Gaps = 26/298 (8%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 45 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 104
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 105 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 161
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD-AIYHCRAE 447
++ C+ G P P I W N+ V N +L V +D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 221
Query: 448 -NDGGMIEASAVLTLEQVEIIP----PRIVLKPEDMDAFKE----TSVQMPCEIESVPPA 498
N I+ ++++ + P L PE + KE + + C E +P
Sbjct: 222 FNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 281
Query: 499 SIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I W K+ + ++ + +L I +VS D+G Y+C A N G ++ + VK
Sbjct: 282 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 339
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 136 bits (328), Expect = 7e-31
Identities = 105/402 (26%), Positives = 172/402 (42%), Gaps = 25/402 (6%)
Query: 160 QPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS 219
QP SV S + + P E ++ E G C+A G P P I W ++
Sbjct: 239 QPISVKVISAKSSRERPPTFLTP--EGNASNKEELRGNVLSLECIAEGLPTPIIYWAKED 296
Query: 220 EVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKS 279
++P N Y+ F+ TL + +E D G ++C+AKN G H + VR KA
Sbjct: 297 GMLPKNRTVYKNFEK-TLQIIHVSEADSGNYQCIAKNALGAIHHT---ISVRVKAA---- 348
Query: 280 PAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLL--NERIILQHNGS 337
P +++ PQ E + C A G PKP ++W NG + + ++ +
Sbjct: 349 ---PYWITAPQNLVLSPGEDGTLI-CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDT 404
Query: 338 ILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQT--AIIGDNVWFTC 395
I+ NVQ + VY C N +G + A+ + V A P I+ P N I C
Sbjct: 405 IIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDC 464
Query: 396 KAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G+P P+I+W++ + ++ + +N L + +D Y C A N GM +
Sbjct: 465 AFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKN 524
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASID--WRKDGSRIVEDD 513
L ++ I V +PE + + V C+++ S+ W KD + D+
Sbjct: 525 EVHLEIKDATWI----VKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDE 580
Query: 514 RISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
R ++ L++ +VS D+G Y C A +AS L+V
Sbjct: 581 RFTVDK-DHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSV 621
Score = 113 bits (271), Expect = 5e-24
Identities = 96/390 (24%), Positives = 159/390 (40%), Gaps = 15/390 (3%)
Query: 178 PCQQPQFESEPND-VEVSFGENAVFTC-VATGEPAPEILWLRDS-EVIPLNENRYEIFDN 234
P + P + E + + + G++ V C G P P I W+ +S + +P +E + +
Sbjct: 148 PSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNG 207
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFA 294
+ E+ + C A+ + + + V+ + + PP F+ TP+ +
Sbjct: 208 DLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFL-TPEGNAS 266
Query: 295 KINETS---VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVY 351
E + +C A G P P + W + N + ++ I +V +D+G Y
Sbjct: 267 NKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNY 326
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT 411
C +N G I ++ + V A P +I P N G++ C+A G PKP I W N
Sbjct: 327 QCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNG 386
Query: 412 VILPIT-GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPR 470
V + I + D + V A+Y C A N+ G + A+A + V PPR
Sbjct: 387 VPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFV---NVLAEPPR 443
Query: 471 IVLKPEDM-DAFKETSVQMPCEIESVPPASIDWRK--DGSRIVEDDRISITVIGSLIIRN 527
I+ + + C P +I+W K GS + ED + + G+L I
Sbjct: 444 ILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPV 502
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
TG Y C A N G V L +KD
Sbjct: 503 AQKDSTGTYTCVARNKLGMAKNEVHLEIKD 532
Score = 99.1 bits (236), Expect = 9e-20
Identities = 95/395 (24%), Positives = 162/395 (41%), Gaps = 38/395 (9%)
Query: 185 ESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF--DNGTLMVHEA 242
+ P D + EN V C A G+P P W R+ ++++ GTL+++
Sbjct: 57 QQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIM 116
Query: 243 NEND----DGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+E +G+++C A+N G A S + R K P+ + + Q
Sbjct: 117 SEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ-------- 168
Query: 299 TSVMFDC-TATGFPKPHVAWYFNG-ERMLLNERIILQHNGSILIKNVQNSDAGV-YTCQV 355
S++ C G P P + W N +R+ +ER+ NG + NV D Y C
Sbjct: 169 -SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYA 227
Query: 356 ENIHGK-ISASVPLEVTA---------PPSFIVV---PTNQTAIIGDNVWFTCKAKGTPK 402
H + I P+ V PP+F+ +N+ + G+ + C A+G P
Sbjct: 228 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 287
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P I W + +LP V + + L ++ V+ D Y C A+N G I + + ++
Sbjct: 288 PIIYWAKEDGMLP-KNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 346
Query: 463 QVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIG 521
P + P+++ + C P I W +G I + D S + G
Sbjct: 347 AA----PYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDG 402
Query: 522 -SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++I NV + Y+C+A N+YG A+ F+ V
Sbjct: 403 DTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNV 437
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/175 (26%), Positives = 78/175 (44%), Gaps = 10/175 (5%)
Query: 199 AVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVA 258
A+ C G P P I W + ++ L+E+ Y + +NGTL + A ++ G + C+A+N
Sbjct: 460 ALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKL 519
Query: 259 GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWY 318
G A ++ + ++ K P V F E V D T + V W
Sbjct: 520 GMAKNE-VHLEIKDATWIVKQPEYAVVQRGSMVSF----ECKVKHDHTLS----LTVLWL 570
Query: 319 FNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
+ + +ER + + +++ +V + D+G YTC +SAS L V AP
Sbjct: 571 KDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 624
Score = 55.2 bits (127), Expect = 1e-06
Identities = 69/298 (23%), Positives = 114/298 (38%), Gaps = 26/298 (8%)
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSIL 339
PP K + +++ C A G P P +W NG +++ + ++ L
Sbjct: 52 PPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTL 111
Query: 340 IKNVQNSD-----AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQ-----TAIIGD 389
I N+ + GVY C N G A+V + PS + T + T G
Sbjct: 112 IINIMSEGKAETYEGVYQCTARNERG---AAVSNNIVVRPSRSPLWTKEKLEPITLQSGQ 168
Query: 390 NVWFTCKAK-GTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD-AIYHCRAE 447
++ C+ G P P I W N+ V N +L V +D Y C A
Sbjct: 169 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYAR 228
Query: 448 -NDGGMIEASAVLTLEQVEIIP----PRIVLKPEDMDAFKE----TSVQMPCEIESVPPA 498
N I+ ++++ + P L PE + KE + + C E +P
Sbjct: 229 FNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTP 288
Query: 499 SIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I W K+ + ++ + +L I +VS D+G Y+C A N G ++ + VK
Sbjct: 289 IIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 346
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 135 bits (326), Expect = 1e-30
Identities = 106/380 (27%), Positives = 167/380 (43%), Gaps = 41/380 (10%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANENDDG 248
DV G+N C A G P P+I W + E +P + EI +G ++ + D+G
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIFNIQLEDEG 306
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
++EC A+N+ GK + A++ V+ A P +V I + + + C AT
Sbjct: 307 IYECEAENIRGKDKHQ-ARIYVQ---------AFPEWVEHINDTEVDIG-SDLYWPCVAT 355
Query: 309 GFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
G P P + W NG H G + + +V +AG+Y C EN +G I A+ L
Sbjct: 356 GKPIPTIRWLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
Query: 369 EVTA-PPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
++ A P+F + P + + G V CK K PKP W + T L + +++ +D
Sbjct: 407 KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 466
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+L + +TR+D IY C AEN+ G ++ L + P RI+L P + D +
Sbjct: 467 G-SLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD----PTRIILAPINADITVGEN 521
Query: 486 VQMPCEIESVPPASID--WRKDG-------SRIVEDDRISITVIGSLIIRNVSVTDTGRY 536
M C P + W +G I + G L+IRN + GRY
Sbjct: 522 ATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRY 581
Query: 537 ECSAFNDYGRDTASVFLTVK 556
C+A +AS L V+
Sbjct: 582 TCTAQTIVDNSSASADLVVR 601
Score = 117 bits (281), Expect = 3e-25
Identities = 92/339 (27%), Positives = 149/339 (43%), Gaps = 19/339 (5%)
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
I +++ R+ NG L + +D G + C + + S +K I E +
Sbjct: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPS-ITKSVFSKFIPLIPIPERTTKP 239
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-I 340
P + K + +V +C A G P P + W E M I +G++L I
Sbjct: 240 YPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEI--STSGAVLKI 297
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
N+Q D G+Y C+ ENI GK + V A P ++ + IG ++++ C A G
Sbjct: 298 FNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGK 357
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P+I+W +N + L L +VT ++ +Y C AEN G I A+A L
Sbjct: 358 PIPTIRWLKNG----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL- 406
Query: 461 LEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
++ + P + P + + A K V + C+ ++ P W K +V RI I
Sbjct: 407 --KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW 464
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
GSL I N++ D G Y C A N+ G+ ++ L + D
Sbjct: 465 EDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Score = 111 bits (266), Expect = 2e-23
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 18/220 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P++ ND EV G + + CVATG+P P I WL+ N Y + G L +++
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLK---------NGYA-YHKGELRLYD 380
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G+++C+A+N G ++ I+ + AP ++ +K+ V
Sbjct: 381 VTFENAGMYQCIAENTYGAIYANAELKIL--------ALAPTFEMNPMKKKILAAKGGRV 432
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C PKP +W E ++ + RI++ +GS+ I N+ +D G+YTC EN GK
Sbjct: 433 IIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGK 492
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+++ L +T P I+ P N +G+N C A P
Sbjct: 493 ANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDP 532
Score = 106 bits (254), Expect = 6e-22
Identities = 101/391 (25%), Positives = 162/391 (41%), Gaps = 40/391 (10%)
Query: 182 PQFESEP-NDV--EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
P FE +P N + E S C A P P W ++ + L +RY + ++
Sbjct: 41 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVI 100
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D G++ C+A N G S A + + + P PP P+ R K +
Sbjct: 101 NNPDKQKDAGIYYCLASNNYGMVRSTEATL-----SFGYLDPFPP--EERPEVR-VKEGK 152
Query: 299 TSVMFDCTATGFPKP-HVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVYTCQ 354
V+ FP W N + + R + Q NG++ I NV+ SD G Y+C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 355 V------ENIHGKISASVPL--EVTAP-PSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPS 404
V +++ K +P+ T P P+ IVV A++G NV C A G P P
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
I+W + V+ P+ +S L + + +D+ IY C AEN G + A + ++
Sbjct: 273 IRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF 330
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
P V D + + + PC P +I W K+G + G L
Sbjct: 331 ----PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK---------GELR 377
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +V+ + G Y+C A N YG A+ L +
Sbjct: 378 LYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 80.2 bits (189), Expect = 5e-14
Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 23/204 (11%)
Query: 182 PQFESEPNDVEV--SFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P FE P ++ + G + C P P+ W + +E + +N +R I+++G+L +
Sbjct: 413 PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-VNSSRILIWEDGSLEI 471
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ ND G++ C A+N GKA+S +I P + P + E
Sbjct: 472 NNITRNDGGIYTCFAENNRGKANSTGTLVITD----------PTRIILAPINADITVGEN 521
Query: 300 SVMFDCTATGFPKPHVA--WYFNG-------ERMLLNERIILQHNGSILIKNVQNSDAGV 350
+ M C A+ P + W FNG E + +L NG +LI+N Q AG
Sbjct: 522 ATM-QCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580
Query: 351 YTCQVENIHGKISASVPLEVTAPP 374
YTC + I SAS L V PP
Sbjct: 581 YTCTAQTIVDNSSASADLVVRGPP 604
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 135 bits (326), Expect = 1e-30
Identities = 106/380 (27%), Positives = 167/380 (43%), Gaps = 41/380 (10%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANENDDG 248
DV G+N C A G P P+I W + E +P + EI +G ++ + D+G
Sbjct: 239 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIFNIQLEDEG 295
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
++EC A+N+ GK + A++ V+ A P +V I + + + C AT
Sbjct: 296 IYECEAENIRGKDKHQ-ARIYVQ---------AFPEWVEHINDTEVDIG-SDLYWPCVAT 344
Query: 309 GFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
G P P + W NG H G + + +V +AG+Y C EN +G I A+ L
Sbjct: 345 GKPIPTIRWLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL 395
Query: 369 EVTA-PPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
++ A P+F + P + + G V CK K PKP W + T L + +++ +D
Sbjct: 396 KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 455
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+L + +TR+D IY C AEN+ G ++ L + P RI+L P + D +
Sbjct: 456 G-SLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD----PTRIILAPINADITVGEN 510
Query: 486 VQMPCEIESVPPASID--WRKDG-------SRIVEDDRISITVIGSLIIRNVSVTDTGRY 536
M C P + W +G I + G L+IRN + GRY
Sbjct: 511 ATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRY 570
Query: 537 ECSAFNDYGRDTASVFLTVK 556
C+A +AS L V+
Sbjct: 571 TCTAQTIVDNSSASADLVVR 590
Score = 117 bits (281), Expect = 3e-25
Identities = 92/339 (27%), Positives = 149/339 (43%), Gaps = 19/339 (5%)
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
I +++ R+ NG L + +D G + C + + S +K I E +
Sbjct: 170 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPS-ITKSVFSKFIPLIPIPERTTKP 228
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-I 340
P + K + +V +C A G P P + W E M I +G++L I
Sbjct: 229 YPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEI--STSGAVLKI 286
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
N+Q D G+Y C+ ENI GK + V A P ++ + IG ++++ C A G
Sbjct: 287 FNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGK 346
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P+I+W +N + L L +VT ++ +Y C AEN G I A+A L
Sbjct: 347 PIPTIRWLKNG----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL- 395
Query: 461 LEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
++ + P + P + + A K V + C+ ++ P W K +V RI I
Sbjct: 396 --KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW 453
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
GSL I N++ D G Y C A N+ G+ ++ L + D
Sbjct: 454 EDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 492
Score = 111 bits (266), Expect = 2e-23
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 18/220 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P++ ND EV G + + CVATG+P P I WL+ N Y + G L +++
Sbjct: 320 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLK---------NGYA-YHKGELRLYD 369
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G+++C+A+N G ++ I+ + AP ++ +K+ V
Sbjct: 370 VTFENAGMYQCIAENTYGAIYANAELKIL--------ALAPTFEMNPMKKKILAAKGGRV 421
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C PKP +W E ++ + RI++ +GS+ I N+ +D G+YTC EN GK
Sbjct: 422 IIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGK 481
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+++ L +T P I+ P N +G+N C A P
Sbjct: 482 ANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDP 521
Score = 106 bits (254), Expect = 6e-22
Identities = 101/391 (25%), Positives = 162/391 (41%), Gaps = 40/391 (10%)
Query: 182 PQFESEP-NDV--EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
P FE +P N + E S C A P P W ++ + L +RY + ++
Sbjct: 30 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVI 89
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D G++ C+A N G S A + + + P PP P+ R K +
Sbjct: 90 NNPDKQKDAGIYYCLASNNYGMVRSTEATL-----SFGYLDPFPP--EERPEVR-VKEGK 141
Query: 299 TSVMFDCTATGFPKP-HVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVYTCQ 354
V+ FP W N + + R + Q NG++ I NV+ SD G Y+C
Sbjct: 142 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 201
Query: 355 V------ENIHGKISASVPL--EVTAP-PSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPS 404
V +++ K +P+ T P P+ IVV A++G NV C A G P P
Sbjct: 202 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 261
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
I+W + V+ P+ +S L + + +D+ IY C AEN G + A + ++
Sbjct: 262 IRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF 319
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
P V D + + + PC P +I W K+G + G L
Sbjct: 320 ----PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK---------GELR 366
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +V+ + G Y+C A N YG A+ L +
Sbjct: 367 LYDVTFENAGMYQCIAENTYGAIYANAELKI 397
Score = 80.2 bits (189), Expect = 5e-14
Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 23/204 (11%)
Query: 182 PQFESEPNDVEV--SFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P FE P ++ + G + C P P+ W + +E + +N +R I+++G+L +
Sbjct: 402 PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-VNSSRILIWEDGSLEI 460
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ ND G++ C A+N GKA+S +I P + P + E
Sbjct: 461 NNITRNDGGIYTCFAENNRGKANSTGTLVITD----------PTRIILAPINADITVGEN 510
Query: 300 SVMFDCTATGFPKPHVA--WYFNG-------ERMLLNERIILQHNGSILIKNVQNSDAGV 350
+ M C A+ P + W FNG E + +L NG +LI+N Q AG
Sbjct: 511 ATM-QCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 569
Query: 351 YTCQVENIHGKISASVPLEVTAPP 374
YTC + I SAS L V PP
Sbjct: 570 YTCTAQTIVDNSSASADLVVRGPP 593
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 135 bits (326), Expect = 1e-30
Identities = 106/380 (27%), Positives = 167/380 (43%), Gaps = 41/380 (10%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANENDDG 248
DV G+N C A G P P+I W + E +P + EI +G ++ + D+G
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIFNIQLEDEG 306
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
++EC A+N+ GK + A++ V+ A P +V I + + + C AT
Sbjct: 307 IYECEAENIRGKDKHQ-ARIYVQ---------AFPEWVEHINDTEVDIG-SDLYWPCVAT 355
Query: 309 GFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
G P P + W NG H G + + +V +AG+Y C EN +G I A+ L
Sbjct: 356 GKPIPTIRWLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
Query: 369 EVTA-PPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
++ A P+F + P + + G V CK K PKP W + T L + +++ +D
Sbjct: 407 KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 466
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+L + +TR+D IY C AEN+ G ++ L + P RI+L P + D +
Sbjct: 467 G-SLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD----PTRIILAPINADITVGEN 521
Query: 486 VQMPCEIESVPPASID--WRKDG-------SRIVEDDRISITVIGSLIIRNVSVTDTGRY 536
M C P + W +G I + G L+IRN + GRY
Sbjct: 522 ATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRY 581
Query: 537 ECSAFNDYGRDTASVFLTVK 556
C+A +AS L V+
Sbjct: 582 TCTAQTIVDNSSASADLVVR 601
Score = 117 bits (281), Expect = 3e-25
Identities = 92/339 (27%), Positives = 149/339 (43%), Gaps = 19/339 (5%)
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
I +++ R+ NG L + +D G + C + + S +K I E +
Sbjct: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPS-ITKSVFSKFIPLIPIPERTTKP 239
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-I 340
P + K + +V +C A G P P + W E M I +G++L I
Sbjct: 240 YPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEI--STSGAVLKI 297
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
N+Q D G+Y C+ ENI GK + V A P ++ + IG ++++ C A G
Sbjct: 298 FNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGK 357
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P+I+W +N + L L +VT ++ +Y C AEN G I A+A L
Sbjct: 358 PIPTIRWLKNG----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL- 406
Query: 461 LEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
++ + P + P + + A K V + C+ ++ P W K +V RI I
Sbjct: 407 --KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW 464
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
GSL I N++ D G Y C A N+ G+ ++ L + D
Sbjct: 465 EDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Score = 111 bits (266), Expect = 2e-23
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 18/220 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P++ ND EV G + + CVATG+P P I WL+ N Y + G L +++
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLK---------NGYA-YHKGELRLYD 380
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G+++C+A+N G ++ I+ + AP ++ +K+ V
Sbjct: 381 VTFENAGMYQCIAENTYGAIYANAELKIL--------ALAPTFEMNPMKKKILAAKGGRV 432
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C PKP +W E ++ + RI++ +GS+ I N+ +D G+YTC EN GK
Sbjct: 433 IIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGK 492
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+++ L +T P I+ P N +G+N C A P
Sbjct: 493 ANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDP 532
Score = 106 bits (254), Expect = 6e-22
Identities = 101/391 (25%), Positives = 162/391 (41%), Gaps = 40/391 (10%)
Query: 182 PQFESEP-NDV--EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
P FE +P N + E S C A P P W ++ + L +RY + ++
Sbjct: 41 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVI 100
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D G++ C+A N G S A + + + P PP P+ R K +
Sbjct: 101 NNPDKQKDAGIYYCLASNNYGMVRSTEATL-----SFGYLDPFPP--EERPEVR-VKEGK 152
Query: 299 TSVMFDCTATGFPKP-HVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVYTCQ 354
V+ FP W N + + R + Q NG++ I NV+ SD G Y+C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 355 V------ENIHGKISASVPL--EVTAP-PSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPS 404
V +++ K +P+ T P P+ IVV A++G NV C A G P P
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
I+W + V+ P+ +S L + + +D+ IY C AEN G + A + ++
Sbjct: 273 IRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF 330
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
P V D + + + PC P +I W K+G + G L
Sbjct: 331 ----PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK---------GELR 377
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +V+ + G Y+C A N YG A+ L +
Sbjct: 378 LYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 80.2 bits (189), Expect = 5e-14
Identities = 58/204 (28%), Positives = 89/204 (43%), Gaps = 23/204 (11%)
Query: 182 PQFESEPNDVEV--SFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P FE P ++ + G + C P P+ W + +E + +N +R I+++G+L +
Sbjct: 413 PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-VNSSRILIWEDGSLEI 471
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ ND G++ C A+N GKA+S +I P + P + E
Sbjct: 472 NNITRNDGGIYTCFAENNRGKANSTGTLVITD----------PTRIILAPINADITVGEN 521
Query: 300 SVMFDCTATGFPKPHVA--WYFNG-------ERMLLNERIILQHNGSILIKNVQNSDAGV 350
+ M C A+ P + W FNG E + +L NG +LI+N Q AG
Sbjct: 522 ATM-QCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580
Query: 351 YTCQVENIHGKISASVPLEVTAPP 374
YTC + I SAS L V PP
Sbjct: 581 YTCTAQTIVDNSSASADLVVRGPP 604
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 135 bits (326), Expect = 1e-30
Identities = 106/380 (27%), Positives = 167/380 (43%), Gaps = 41/380 (10%)
Query: 190 DVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM-VHEANENDDG 248
DV G+N C A G P P+I W + E +P + EI +G ++ + D+G
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIFNIQLEDEG 306
Query: 249 LFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTAT 308
++EC A+N+ GK + A++ V+ A P +V I + + + C AT
Sbjct: 307 IYECEAENIRGKDKHQ-ARIYVQ---------AFPEWVEHINDTEVDIG-SDLYWPCVAT 355
Query: 309 GFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPL 368
G P P + W NG H G + + +V +AG+Y C EN +G I A+ L
Sbjct: 356 GKPIPTIRWLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL 406
Query: 369 EVTA-PPSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDD 425
++ A P+F + P + + G V CK K PKP W + T L + +++ +D
Sbjct: 407 KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED 466
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
+L + +TR+D IY C AEN+ G ++ L + P RI+L P + D +
Sbjct: 467 G-SLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD----PTRIILAPINADITVGEN 521
Query: 486 VQMPCEIESVPPASID--WRKDG-------SRIVEDDRISITVIGSLIIRNVSVTDTGRY 536
M C P + W +G I + G L+IRN + GRY
Sbjct: 522 ATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRY 581
Query: 537 ECSAFNDYGRDTASVFLTVK 556
C+A +AS L V+
Sbjct: 582 TCTAQTIVDNSSASADLVVR 601
Score = 117 bits (281), Expect = 3e-25
Identities = 92/339 (27%), Positives = 149/339 (43%), Gaps = 19/339 (5%)
Query: 222 IPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPA 281
I +++ R+ NG L + +D G + C + + S +K I E +
Sbjct: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPS-ITKSVFSKFIPLIPIPERTTKP 239
Query: 282 PPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSIL-I 340
P + K + +V +C A G P P + W E M I +G++L I
Sbjct: 240 YPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEI--STSGAVLKI 297
Query: 341 KNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
N+Q D G+Y C+ ENI GK + V A P ++ + IG ++++ C A G
Sbjct: 298 FNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGK 357
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLT 460
P P+I+W +N + L L +VT ++ +Y C AEN G I A+A L
Sbjct: 358 PIPTIRWLKNG----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAEL- 406
Query: 461 LEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT 518
++ + P + P + + A K V + C+ ++ P W K +V RI I
Sbjct: 407 --KILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIW 464
Query: 519 VIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
GSL I N++ D G Y C A N+ G+ ++ L + D
Sbjct: 465 EDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
Score = 111 bits (266), Expect = 2e-23
Identities = 62/220 (28%), Positives = 106/220 (48%), Gaps = 18/220 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P++ ND EV G + + CVATG+P P I WL+ N Y + G L +++
Sbjct: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLK---------NGYA-YHKGELRLYD 380
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G+++C+A+N G ++ I+ + AP ++ +K+ V
Sbjct: 381 VTFENAGMYQCIAENTYGAIYANAELKIL--------ALAPTFEMNPMKKKILAAKGGRV 432
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
+ +C PKP +W E ++ + RI++ +GS+ I N+ +D G+YTC EN GK
Sbjct: 433 IIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGK 492
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTP 401
+++ L +T P I+ P N +G+N C A P
Sbjct: 493 ANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDP 532
Score = 106 bits (254), Expect = 6e-22
Identities = 101/391 (25%), Positives = 162/391 (41%), Gaps = 40/391 (10%)
Query: 182 PQFESEP-NDV--EVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLM 238
P FE +P N + E S C A P P W ++ + L +RY + ++
Sbjct: 41 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVI 100
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ + D G++ C+A N G S A + + + P PP P+ R K +
Sbjct: 101 NNPDKQKDAGIYYCLASNNYGMVRSTEATL-----SFGYLDPFPP--EERPEVR-VKEGK 152
Query: 299 TSVMFDCTATGFPKP-HVAWYFNGERMLL---NERIILQHNGSILIKNVQNSDAGVYTCQ 354
V+ FP W N + + R + Q NG++ I NV+ SD G Y+C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 355 V------ENIHGKISASVPL--EVTAP-PSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPS 404
V +++ K +P+ T P P+ IVV A++G NV C A G P P
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
I+W + V+ P+ +S L + + +D+ IY C AEN G + A + ++
Sbjct: 273 IRWRK--VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF 330
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
P V D + + + PC P +I W K+G + G L
Sbjct: 331 ----PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK---------GELR 377
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ +V+ + G Y+C A N YG A+ L +
Sbjct: 378 LYDVTFENAGMYQCIAENTYGAIYANAELKI 408
Score = 74.9 bits (176), Expect = 2e-12
Identities = 56/200 (28%), Positives = 87/200 (43%), Gaps = 23/200 (11%)
Query: 182 PQFESEPNDVEV--SFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
P FE P ++ + G + C P P+ W + +E + +N +R I+++G+L +
Sbjct: 413 PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-VNSSRILIWEDGSLEI 471
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+ ND G++ C A+N GKA+S +I P + P + E
Sbjct: 472 NNITRNDGGIYTCFAENNRGKANSTGTLVITD----------PTRIILAPINADITVGEN 521
Query: 300 SVMFDCTATGFPKPHVA--WYFNG-------ERMLLNERIILQHNGSILIKNVQNSDAGV 350
+ M C A+ P + W FNG E + +L NG +LI+N Q AG
Sbjct: 522 ATM-QCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580
Query: 351 YTCQVENIHGKISASVPLEV 370
YTC + I SAS L V
Sbjct: 581 YTCTAQTIVDNSSASADLVV 600
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRPQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.5 bits (170), Expect = 9e-12
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RPQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 134 bits (325), Expect = 2e-30
Identities = 99/383 (25%), Positives = 175/383 (45%), Gaps = 24/383 (6%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSE-VIPL-NENRYEIFDNGTLMVH 240
+F S+ V G+ + C GEP P I W ++ + + P+ ++R + +G L +
Sbjct: 75 RFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQIS 134
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
D G++ C A+N A A++ + H+ F+ P A + +
Sbjct: 135 RLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQL---YFLQRPSNVVAIEGKDA 191
Query: 301 VMFDCTATGFPKPHVAWYFNGERM--LLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
V+ C + G+P P W GE + L +++ L ++LI NV + D+G+YTC V
Sbjct: 192 VLEGCVS-GYPPPSFTW-LRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYK 249
Query: 359 HGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN-TVILPIT 417
+ ISAS L V PP F+ P+N A ++ F C G P P++ W +N V++P
Sbjct: 250 NENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSD 309
Query: 418 GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL-----TLEQVEIIP--PR 470
++ NL +L V + D+ Y C AEN+ G + SA L + ++P PR
Sbjct: 310 YFQIVG--GSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPR 367
Query: 471 IVLKPEDMDAFKETSVQMPCEIE-SVPPASIDWRKDGSRIVEDDRISITVIGS--LIIRN 527
V+ F S + P E + ++ ++ + ++G + ++ T GS L + N
Sbjct: 368 DVVPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDN--RERALNTTQPGSLQLTVGN 425
Query: 528 VSVTDTGRYECSAFNDYGRDTAS 550
+ + A+N++G +S
Sbjct: 426 LKPEAMYTFRVVAYNEWGPGESS 448
Score = 124 bits (300), Expect = 2e-27
Identities = 97/384 (25%), Positives = 164/384 (42%), Gaps = 35/384 (9%)
Query: 211 PEILWLRDSEVIPLN-ENRYEIFDNGTLMVHEA-----NENDDGLFECMAK-NVAGKAHS 263
P I W +D + L + R + NG+L++ ++ D+GL++C A +G S
Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63
Query: 264 KPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGER 323
+ AK+ V P F+S + A + +T V+ C G P P + W N +
Sbjct: 64 RTAKVAVA---------GPLRFLSQTESVTAFMGDT-VLLKCEVIGEPMPTIHWQKNQQD 113
Query: 324 MLL---NERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHGKISASVPLEVTAPPS---- 375
+ + R+++ +G++ I +Q D G+Y C N + + + + P
Sbjct: 114 LTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQ 173
Query: 376 --FIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLE 433
F+ P+N AI G + G P PS W R ++ + NL +
Sbjct: 174 LYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISN 233
Query: 434 VTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIE 493
VT DD +Y C I ASA LT+ ++PP + P ++ A++ ++ C +
Sbjct: 234 VTDDDSGMYTCVVTYKNENISASAELTV----LVPPWFLNHPSNLYAYESMDIEFECTVS 289
Query: 494 SVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFL 553
P +++W K+G ++ D I +L I V +D G Y+C A N+ G S L
Sbjct: 290 GKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQL 349
Query: 554 TVKDNLLPGDAYVNIALTQAMRDV 577
V +P + L A RDV
Sbjct: 350 IVPKPAIPSSS----VLPSAPRDV 369
Score = 92.3 bits (219), Expect = 1e-17
Identities = 58/204 (28%), Positives = 92/204 (45%), Gaps = 13/204 (6%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+Q F P++V G++AV +G P P WLR EVI L +Y + L++
Sbjct: 172 RQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLI 231
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
++D G++ C+ + S A++ V PP F++ P +A
Sbjct: 232 SNVTDDDSGMYTCVV-TYKNENISASAELTVL---------VPPWFLNHPSNLYA-YESM 280
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
+ F+CT +G P P V W NG+ ++ ++ + ++ I V SD G Y C EN
Sbjct: 281 DIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEA 340
Query: 360 GKISASVPLEVTAP--PSFIVVPT 381
G S L V P PS V+P+
Sbjct: 341 GNAQTSAQLIVPKPAIPSSSVLPS 364
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor
precursor PTK7-5 protein.
Length = 816
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 101 bits (241), Expect = 2e-20
Identities = 67/227 (29%), Positives = 104/227 (45%), Gaps = 14/227 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW 407
+I A V L V +F V P T G C+A+G PKP I+W
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW 625
Score = 89.0 bits (211), Expect = 1e-16
Identities = 85/314 (27%), Positives = 129/314 (41%), Gaps = 29/314 (9%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWR 503
CE + P I W+
Sbjct: 613 CEAQGDPKPLIQWK 626
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 231 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 290
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 291 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 344
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 345 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 399
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 400 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 459
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 460 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 515
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 516 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 570
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 571 IASNGPQGQIRAHVQLTV 588
Score = 109 bits (261), Expect = 9e-23
Identities = 106/379 (27%), Positives = 159/379 (41%), Gaps = 34/379 (8%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 336 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 393
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 394 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 442
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 443 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 500
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 501 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 556
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 557 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 612
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFNDYG 545
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 613 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCN 671
Query: 546 RDTASVFLTVKDNLLPGDA 564
L V D +P ++
Sbjct: 672 IKHTEAPLYVVDKPVPEES 690
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 412 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 470
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 471 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 522
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 523 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 578
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 579 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 638
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 639 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 679
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 136 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 195
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 196 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 248
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 249 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 308
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 309 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 364
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 365 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 418
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 419 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 478
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 479 YRCMSSTPAGSIEAQARVQVLEKL 502
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 90
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 91 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 146
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 147 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 265
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 266 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 326 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 380
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 381 IAESDAGVYTCHAANLAGQRRQDVNITV 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 33 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 91
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 92 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 151
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 152 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 211
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 212 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 271
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 272 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Score = 58.8 bits (136), Expect = 1e-07
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 594 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 653
Query: 242 ANENDDGLFECMAKNVAGKAHSK-PAKMIVRRKAEEHKSPAPP 283
D G + C+A N H++ P ++ + EE + P P
Sbjct: 654 VAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSP 696
>AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine
kinase 7 isoform a precursor variant protein.
Length = 773
Score = 134 bits (325), Expect = 2e-30
Identities = 108/378 (28%), Positives = 169/378 (44%), Gaps = 30/378 (7%)
Query: 188 PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENR------YEIFDNGTLMVHE 241
P DV V+ E A+F C + +P P + WL + E N +R +F NG+L++ +
Sbjct: 271 PQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQ 330
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ G++ C+ + G A + + + E+ P VF + ++R +
Sbjct: 331 VRPRNAGIYRCIGQGQRGPPIILEATLHLA-EIEDMPLFEPRVFTAGSEERVTCL----- 384
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK 361
G P+P V W G R+ + R+ Q +++ N+ SDAGVYTC N+ G+
Sbjct: 385 ----PPKGLPEPSVWWEHAGVRLPTHGRVY-QKGHELVLANIAESDAGVYTCHAANLAGQ 439
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
V + V PS++ P + G + C + TPKP++ WYRN +++
Sbjct: 440 RRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFE 499
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA-VLTLEQVEIIPPRIVLKPED-MD 479
+ N L + V D Y C + G IEA A V LE+++ PP +P+ M+
Sbjct: 500 VF-KNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPP---QPQQCME 555
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYEC 538
KE +V PC +I W R DGS + E G+L V+ D G Y C
Sbjct: 556 FDKEATV--PCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTC 610
Query: 539 SAFN-DYGRDTASVFLTV 555
A N G+ A V LTV
Sbjct: 611 IASNGPQGQIRAHVQLTV 628
Score = 109 bits (261), Expect = 9e-23
Identities = 81/281 (28%), Positives = 124/281 (44%), Gaps = 16/281 (5%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P + +P D ++ G+ C+ P P ++W R+ +I ++R+E+F NGTL ++
Sbjct: 452 PSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLIS-EDSRFEVFKNGTLRINS 510
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
D + CM+ AG ++ ++ E+ K PP PQ+ E +V
Sbjct: 511 VEVYDGTWYRCMSSTPAGSIEAQARVQVL----EKLKFTPPP----QPQQCMEFDKEATV 562
Query: 302 MFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHG 360
C+ATG KP + W + L E + + G++ V DAG YTC N G
Sbjct: 563 --PCSATGREKPTIKWE-RADGSSLPEWVT-DNAGTLHFARVTRDDAGNYTCIASNGPQG 618
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPIT--G 418
+I A V L V +F V P T G C+A+G PKP I+W IL T G
Sbjct: 619 QIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLG 678
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVL 459
+ N +L + +V +D Y C A N + A L
Sbjct: 679 PRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPL 719
Score = 107 bits (257), Expect = 3e-22
Identities = 102/357 (28%), Positives = 152/357 (42%), Gaps = 34/357 (9%)
Query: 196 GENAVFTCVAT-GEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMA 254
G TC+ G P P + W +P + Y+ L++ E+D G++ C A
Sbjct: 376 GSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQ--KGHELVLANIAESDAGVYTCHA 433
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
N+AG+ RR+ P ++ PQ + + + DC PKP
Sbjct: 434 ANLAGQ----------RRQDVNITVATVPSWLKKPQDSQLEEGKPGYL-DCLTQATPKPT 482
Query: 315 VAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA 372
V WY N +ML++E R + NG++ I +V+ D Y C G I A ++V
Sbjct: 483 VVWYRN--QMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLE 540
Query: 373 PPSFIVVPTNQTAIIGDN-VWFTCKAKGTPKPSIKWYR-NTVILPITGNLVLSDDNQNLT 430
F P Q + D C A G KP+IKW R + LP ++D+ L
Sbjct: 541 KLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEW----VTDNAGTLH 596
Query: 431 LLEVTRDDDAIYHCRAENDG-GMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMP 489
VTRDD Y C A N G I A LT+ + ++PE ++ + +
Sbjct: 597 FARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA----VFITFKVEPERTTVYQGHTALLQ 652
Query: 490 CEIESVPPASIDWRKDGSRIVEDD----RISITVIGSLIIRNVSVTDTGRYECSAFN 542
CE + P I W K RI++ R+ I GSL+I +V+ D+GRY C A N
Sbjct: 653 CEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGN 708
Score = 101 bits (243), Expect = 1e-20
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 30/384 (7%)
Query: 189 NDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG-TLMVHEANENDD 247
++ E+ C G P P W RD + ++ + + L + A
Sbjct: 176 SEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHS 235
Query: 248 GLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTA 307
GL+ C A + G+A S ++ A+E + V PQ E + MF C
Sbjct: 236 GLYSCCAHSAFGQACS--SQNFTLSIADESFARV----VLAPQDVVVARYEEA-MFHCQF 288
Query: 308 TGFPKPHVAWYFNGERMLLNE-------RIILQHNGSILIKNVQNSDAGVYTCQVENIHG 360
+ P P + W F E + N R + NGS+L+ V+ +AG+Y C + G
Sbjct: 289 SAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRG 348
Query: 361 K---ISASVPL-EVTAPPSFIVVPTNQTAIIGDNVWFTC-KAKGTPKPSIKWYRNTVILP 415
+ A++ L E+ P F P TA G TC KG P+PS+ W V LP
Sbjct: 349 PPIILEATLHLAEIEDMPLF--EPRVFTA--GSEERVTCLPPKGLPEPSVWWEHAGVRLP 404
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP 475
G + L L + D +Y C A N G +T+ V P + KP
Sbjct: 405 THGRVY--QKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATV----PSWLKKP 458
Query: 476 EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGR 535
+D + + C ++ P ++ W ++ I ED R + G+L I +V V D
Sbjct: 459 QDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTW 518
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
Y C + G A + V + L
Sbjct: 519 YRCMSSTPAGSIEAQARVQVLEKL 542
Score = 80.6 bits (190), Expect = 3e-14
Identities = 89/388 (22%), Positives = 151/388 (38%), Gaps = 29/388 (7%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F +P+ + G A+ C + WL D + E R F G+ + A
Sbjct: 74 FIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERR---FAQGSSLSFAAV 130
Query: 244 EN--DDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSV 301
+ D G F+C+A++ ++ A K E A PV + P +T V
Sbjct: 131 DRLQDSGTFQCVARDDVTGEEARSANASFNIKWIE----AGPVVLKHPASEAEIQPQTQV 186
Query: 302 MFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
C G P+P W+ +G + + + ++ ++ +G+Y+C +
Sbjct: 187 TLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 246
Query: 360 GKISASVPLEVT-APPSFI-VVPTNQTAIIG--DNVWFTCKAKGTPKPSIKWYRNTVILP 415
G+ +S ++ A SF VV Q ++ + F C+ P PS++W P
Sbjct: 247 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDE-TP 305
Query: 416 ITG-------NLVLSDDNQNLTLLEVTRDDDAIYHCRAEND-GGMIEASAVLTLEQVEII 467
IT N +L L +V + IY C + G I A L L ++E +
Sbjct: 306 ITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 365
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRN 527
P + +P A E V + +P S+ W G R+ R+ L++ N
Sbjct: 366 P---LFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHAGVRLPTHGRV-YQKGHELVLAN 420
Query: 528 VSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ +D G Y C A N G+ V +TV
Sbjct: 421 IAESDAGVYTCHAANLAGQRRQDVNITV 448
Score = 72.1 bits (169), Expect = 1e-11
Identities = 63/270 (23%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 284 VFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV 343
VF+ P + A + + C HV W +G + ER Q +
Sbjct: 73 VFIKQPSSQDA-LQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVD 131
Query: 344 QNSDAGVYTCQV-ENIHGK----ISASVPLE-VTAPPSFIVVPTNQTAIIGDN-VWFTCK 396
+ D+G + C +++ G+ +AS ++ + A P + P ++ I V C
Sbjct: 132 RLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCH 191
Query: 397 AKGTPKPSIKWYRN-TVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEA 455
G P+P+ +W+R+ T + N +S +NLTL + +Y C A + G +
Sbjct: 192 IDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACS 251
Query: 456 SAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWR-KDGSRIVEDD- 513
S TL + R+VL P+D+ + C+ + PP S+ W +D + I
Sbjct: 252 SQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSR 311
Query: 514 -----RISITVIGSLIIRNVSVTDTGRYEC 538
R ++ GSL++ V + G Y C
Sbjct: 312 PPHLRRATVFANGSLLLTQVRPRNAGIYRC 341
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 2/89 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNE--NRYEIFDNGTLMVHE 241
F+ EP V G A+ C A G+P P I W ++ + R IF NG+L++H+
Sbjct: 634 FKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHD 693
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIV 270
D G + C+A N H++ +V
Sbjct: 694 VAPEDSGRYTCIAGNSCNIKHTEAPLYVV 722
Score = 52.4 bits (120), Expect = 1e-05
Identities = 52/184 (28%), Positives = 74/184 (40%), Gaps = 22/184 (11%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLR-DSEVIPLNENRYEIFDN-GTLMVHEANENDDGLF 250
+ F + A C ATG P I W R D +P + DN GTL +D G +
Sbjct: 554 MEFDKEATVPCSATGREKPTIKWERADGSSLP-----EWVTDNAGTLHFARVTRDDAGNY 608
Query: 251 ECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF 310
C+A N P I +A + A + +R + + C A G
Sbjct: 609 TCIASN-------GPQGQI---RAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGD 658
Query: 311 PKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASV 366
PKP + W +R+L L R+ + NGS++I +V D+G YTC N
Sbjct: 659 PKPLIQWK-GKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEA 717
Query: 367 PLEV 370
PL V
Sbjct: 718 PLYV 721
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 134 bits (323), Expect = 3e-30
Identities = 108/377 (28%), Positives = 172/377 (45%), Gaps = 21/377 (5%)
Query: 191 VEVSFGENAVFTCVATGEPAPEIL--WLRDS--EVIPLNENRYEIFDNGTLMVHEANEND 246
V V G+ V C + +PEI+ W+ + + + R+ + G L + + +D
Sbjct: 205 VSVREGQGVVLMC-SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSD 263
Query: 247 DGLFECMAKNVAGKAH--SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
G + C+ KN A S P + +R + P + V P A T+V +
Sbjct: 264 VGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYE-PKIEVHFPFTVTAA-KGTTVKME 321
Query: 305 CTATGFPKPHVAWY-FNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKI 362
C A G P P + W NG + + L+ + ++L I NVQ DAG+Y C+ EN GK
Sbjct: 322 CFALGNPVPTITWMKVNG---YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKN 378
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S L+V P ++ + G + + CKA G P+P+ +W +N V P++ +
Sbjct: 379 SFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV--PLSPQSRV 436
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDA 480
N L + V + D +Y C AEN G I ASA L ++ P L + +
Sbjct: 437 EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL---KILASAPTFALNQLKKTIIV 493
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSA 540
K+ V + C+ + P +I W+K + E+ RI+I GSL I N S +D G+Y C
Sbjct: 494 TKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRG 553
Query: 541 FNDYGRDTASVFLTVKD 557
N +G L+VK+
Sbjct: 554 ENVFGSAEIIASLSVKE 570
Score = 127 bits (306), Expect = 3e-28
Identities = 104/373 (27%), Positives = 166/373 (44%), Gaps = 36/373 (9%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+P+ E P V + G C A G P P I W++ + IP + L +
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK--SQAVLEI 356
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+D G++EC A+N GK + + K + +P +
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLR-------- 408
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
++C ATG P+P W NG + R+ + NG ++I NV SDAG+Y C EN +
Sbjct: 409 ---WECKATGKPRPTYRWLKNGVPLSPQSRVEMV-NGVLMIHNVNQSDAGMYQCLAENKY 464
Query: 360 GKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
G I AS L++ A P+F + +T I+ V CK +G+PKP+I W + +
Sbjct: 465 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRE 524
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
+ + D +L +L ++ D+ Y CR EN G E A L++++ P RI L P+
Sbjct: 525 NKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE----PTRIELTPK 579
Query: 477 DMDAFKETSVQMPCEIESVPPASID----WRKDGSRIVEDDR----ISITVIGS---LII 525
+ S+ + C+ ++ AS+D W G I ++ SI S L+I
Sbjct: 580 RTELTVGESIVLNCK--AIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 637
Query: 526 RNVSVTDTGRYEC 538
RN+ + GRY C
Sbjct: 638 RNILLMHAGRYGC 650
Score = 125 bits (301), Expect = 1e-27
Identities = 116/424 (27%), Positives = 166/424 (39%), Gaps = 36/424 (8%)
Query: 151 WMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEV---SFGENAVFTCVATG 207
W+ A Y P ++ +S A K + P F EP+D+ S + C G
Sbjct: 69 WLGAAQNYYSPINLYHSS-DAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRG 127
Query: 208 EPAPEILWLRDSEVIPLNEN-RYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPA 266
P P WLR+ I L + RY + D ++ + + D G ++C+A N G S+ A
Sbjct: 128 NPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREA 187
Query: 267 KMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF-PKPHVAWYFNGERML 325
+ V V Q V+ C+ P+ +W FN
Sbjct: 188 TLQFAYLGNFSGRTRSAVSVREGQ---------GVVLMCSPPPHSPEIIYSWVFNEFPSF 238
Query: 326 LNE---RIILQHNGSILIKNVQNSDAGVYTCQVENIHGK---ISASVPLEVT-------- 371
+ E R I Q G++ I VQ SD G Y C V+N +S PL +
Sbjct: 239 VAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEY 298
Query: 372 APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTL 431
P + P TA G V C A G P P+I W + +P L S L +
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS--QAVLEI 356
Query: 432 LEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCE 491
V DD IY CRAEN G L + P V K D + ++ C+
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY----PHWVEKLNDTQLDSGSPLRWECK 412
Query: 492 IESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASV 551
P + W K+G + R+ + V G L+I NV+ +D G Y+C A N YG AS
Sbjct: 413 ATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA 471
Query: 552 FLTV 555
L +
Sbjct: 472 ELKI 475
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 21/191 (10%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFEC 252
V+ + V C G P P I W + + N+ R I +G+L + A+++D+G + C
Sbjct: 493 VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVC 551
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+NV G A ++I +E P TP++ + E S++ +C A
Sbjct: 552 RGENVFGSA-----EIIASLSVKE-----PTRIELTPKRTELTVGE-SIVLNCKAIHDAS 600
Query: 313 PHVAWYFNGERMLLN--------ERIILQHNGS-ILIKNVQNSDAGVYTCQVENIHGKIS 363
V +Y+ + ++ E I Q + + ++I+N+ AG Y C+V+ +S
Sbjct: 601 LDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVS 660
Query: 364 ASVPLEVTAPP 374
L V PP
Sbjct: 661 DEAELLVRGPP 671
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 134 bits (323), Expect = 3e-30
Identities = 108/377 (28%), Positives = 172/377 (45%), Gaps = 21/377 (5%)
Query: 191 VEVSFGENAVFTCVATGEPAPEIL--WLRDS--EVIPLNENRYEIFDNGTLMVHEANEND 246
V V G+ V C + +PEI+ W+ + + + R+ + G L + + +D
Sbjct: 131 VSVREGQGVVLMC-SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSD 189
Query: 247 DGLFECMAKNVAGKAH--SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
G + C+ KN A S P + +R + P + V P A T+V +
Sbjct: 190 VGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYE-PKIEVHFPFTVTAA-KGTTVKME 247
Query: 305 CTATGFPKPHVAWY-FNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKI 362
C A G P P + W NG + + L+ + ++L I NVQ DAG+Y C+ EN GK
Sbjct: 248 CFALGNPVPTITWMKVNG---YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKN 304
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S L+V P ++ + G + + CKA G P+P+ +W +N V P++ +
Sbjct: 305 SFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV--PLSPQSRV 362
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDA 480
N L + V + D +Y C AEN G I ASA L ++ P L + +
Sbjct: 363 EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL---KILASAPTFALNQLKKTIIV 419
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSA 540
K+ V + C+ + P +I W+K + E+ RI+I GSL I N S +D G+Y C
Sbjct: 420 TKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRG 479
Query: 541 FNDYGRDTASVFLTVKD 557
N +G L+VK+
Sbjct: 480 ENVFGSAEIIASLSVKE 496
Score = 127 bits (306), Expect = 3e-28
Identities = 104/373 (27%), Positives = 166/373 (44%), Gaps = 36/373 (9%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+P+ E P V + G C A G P P I W++ + IP + L +
Sbjct: 225 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK--SQAVLEI 282
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+D G++EC A+N GK + + K + +P +
Sbjct: 283 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLR-------- 334
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
++C ATG P+P W NG + R+ + NG ++I NV SDAG+Y C EN +
Sbjct: 335 ---WECKATGKPRPTYRWLKNGVPLSPQSRVEMV-NGVLMIHNVNQSDAGMYQCLAENKY 390
Query: 360 GKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
G I AS L++ A P+F + +T I+ V CK +G+PKP+I W + +
Sbjct: 391 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRE 450
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
+ + D +L +L ++ D+ Y CR EN G E A L++++ P RI L P+
Sbjct: 451 NKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE----PTRIELTPK 505
Query: 477 DMDAFKETSVQMPCEIESVPPASID----WRKDGSRIVEDDR----ISITVIGS---LII 525
+ S+ + C+ ++ AS+D W G I ++ SI S L+I
Sbjct: 506 RTELTVGESIVLNCK--AIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 563
Query: 526 RNVSVTDTGRYEC 538
RN+ + GRY C
Sbjct: 564 RNILLMHAGRYGC 576
Score = 119 bits (286), Expect = 8e-26
Identities = 109/393 (27%), Positives = 154/393 (39%), Gaps = 35/393 (8%)
Query: 182 PQFESEPNDVEV---SFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN-RYEIFDNGTL 237
P F EP+D+ S + C G P P WLR+ I L + RY + D +
Sbjct: 25 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 84
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + + D G ++C+A N G S+ A + V V Q
Sbjct: 85 ISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQ------- 137
Query: 298 ETSVMFDCTATGF-PKPHVAWYFNGERMLLNE---RIILQHNGSILIKNVQNSDAGVYTC 353
V+ C+ P+ +W FN + E R I Q G++ I VQ SD G Y C
Sbjct: 138 --GVVLMCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYIC 195
Query: 354 QVENIHGK---ISASVPLEVT--------APPSFIVVPTNQTAIIGDNVWFTCKAKGTPK 402
V+N +S PL + P + P TA G V C A G P
Sbjct: 196 LVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPV 255
Query: 403 PSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
P+I W + +P L S L + V DD IY CRAEN G L +
Sbjct: 256 PTITWMKVNGYIPSKARLRKS--QAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVY 313
Query: 463 QVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGS 522
P V K D + ++ C+ P + W K+G + R+ + V G
Sbjct: 314 TY----PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEM-VNGV 368
Query: 523 LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
L+I NV+ +D G Y+C A N YG AS L +
Sbjct: 369 LMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 401
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 21/191 (10%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFEC 252
V+ + V C G P P I W + + N+ R I +G+L + A+++D+G + C
Sbjct: 419 VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVC 477
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+NV G A ++I +E P TP++ + E S++ +C A
Sbjct: 478 RGENVFGSA-----EIIASLSVKE-----PTRIELTPKRTELTVGE-SIVLNCKAIHDAS 526
Query: 313 PHVAWYFNGERMLLN--------ERIILQHNGS-ILIKNVQNSDAGVYTCQVENIHGKIS 363
V +Y+ + ++ E I Q + + ++I+N+ AG Y C+V+ +S
Sbjct: 527 LDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVS 586
Query: 364 ASVPLEVTAPP 374
L V PP
Sbjct: 587 DEAELLVRGPP 597
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 134 bits (323), Expect = 3e-30
Identities = 108/377 (28%), Positives = 172/377 (45%), Gaps = 21/377 (5%)
Query: 191 VEVSFGENAVFTCVATGEPAPEIL--WLRDS--EVIPLNENRYEIFDNGTLMVHEANEND 246
V V G+ V C + +PEI+ W+ + + + R+ + G L + + +D
Sbjct: 205 VSVREGQGVVLMC-SPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSD 263
Query: 247 DGLFECMAKNVAGKAH--SKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFD 304
G + C+ KN A S P + +R + P + V P A T+V +
Sbjct: 264 VGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYE-PKIEVHFPFTVTAA-KGTTVKME 321
Query: 305 CTATGFPKPHVAWY-FNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVENIHGKI 362
C A G P P + W NG + + L+ + ++L I NVQ DAG+Y C+ EN GK
Sbjct: 322 CFALGNPVPTITWMKVNG---YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKN 378
Query: 363 SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVL 422
S L+V P ++ + G + + CKA G P+P+ +W +N V P++ +
Sbjct: 379 SFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV--PLSPQSRV 436
Query: 423 SDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK--PEDMDA 480
N L + V + D +Y C AEN G I ASA L ++ P L + +
Sbjct: 437 EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL---KILASAPTFALNQLKKTIIV 493
Query: 481 FKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSA 540
K+ V + C+ + P +I W+K + E+ RI+I GSL I N S +D G+Y C
Sbjct: 494 TKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRG 553
Query: 541 FNDYGRDTASVFLTVKD 557
N +G L+VK+
Sbjct: 554 ENVFGSAEIIASLSVKE 570
Score = 127 bits (306), Expect = 3e-28
Identities = 104/373 (27%), Positives = 166/373 (44%), Gaps = 36/373 (9%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+P+ E P V + G C A G P P I W++ + IP + L +
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK--SQAVLEI 356
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+D G++EC A+N GK + + K + +P +
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLR-------- 408
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
++C ATG P+P W NG + R+ + NG ++I NV SDAG+Y C EN +
Sbjct: 409 ---WECKATGKPRPTYRWLKNGVPLSPQSRVEMV-NGVLMIHNVNQSDAGMYQCLAENKY 464
Query: 360 GKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
G I AS L++ A P+F + +T I+ V CK +G+PKP+I W + +
Sbjct: 465 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRE 524
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
+ + D +L +L ++ D+ Y CR EN G E A L++++ P RI L P+
Sbjct: 525 NKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE----PTRIELTPK 579
Query: 477 DMDAFKETSVQMPCEIESVPPASID----WRKDGSRIVEDDR----ISITVIGS---LII 525
+ S+ + C+ ++ AS+D W G I ++ SI S L+I
Sbjct: 580 RTELTVGESIVLNCK--AIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 637
Query: 526 RNVSVTDTGRYEC 538
RN+ + GRY C
Sbjct: 638 RNILLMHAGRYGC 650
Score = 125 bits (301), Expect = 1e-27
Identities = 116/424 (27%), Positives = 166/424 (39%), Gaps = 36/424 (8%)
Query: 151 WMHVAATCYQPASVTGTSLAAMKHHDLPCQQPQFESEPNDVEV---SFGENAVFTCVATG 207
W+ A Y P ++ +S A K + P F EP+D+ S + C G
Sbjct: 69 WLGAAQNYYSPINLYHSS-DAFKQDESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRG 127
Query: 208 EPAPEILWLRDSEVIPLNEN-RYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPA 266
P P WLR+ I L + RY + D ++ + + D G ++C+A N G S+ A
Sbjct: 128 NPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREA 187
Query: 267 KMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGF-PKPHVAWYFNGERML 325
+ V V Q V+ C+ P+ +W FN
Sbjct: 188 TLQFAYLGNFSGRTRSAVSVREGQ---------GVVLMCSPPPHSPEIIYSWVFNEFPSF 238
Query: 326 LNE---RIILQHNGSILIKNVQNSDAGVYTCQVENIHGK---ISASVPLEVT-------- 371
+ E R I Q G++ I VQ SD G Y C V+N +S PL +
Sbjct: 239 VAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEY 298
Query: 372 APPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTL 431
P + P TA G V C A G P P+I W + +P L S L +
Sbjct: 299 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS--QAVLEI 356
Query: 432 LEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCE 491
V DD IY CRAEN G L + P V K D + ++ C+
Sbjct: 357 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTY----PHWVEKLNDTQLDSGSPLRWECK 412
Query: 492 IESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASV 551
P + W K+G + R+ + V G L+I NV+ +D G Y+C A N YG AS
Sbjct: 413 ATGKPRPTYRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYGAIYASA 471
Query: 552 FLTV 555
L +
Sbjct: 472 ELKI 475
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 21/191 (10%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFEC 252
V+ + V C G P P I W + + N+ R I +G+L + A+++D+G + C
Sbjct: 493 VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVC 551
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+NV G A ++I +E P TP++ + E S++ +C A
Sbjct: 552 RGENVFGSA-----EIIASLSVKE-----PTRIELTPKRTELTVGE-SIVLNCKAIHDAS 600
Query: 313 PHVAWYFNGERMLLN--------ERIILQHNGS-ILIKNVQNSDAGVYTCQVENIHGKIS 363
V +Y+ + ++ E I Q + + ++I+N+ AG Y C+V+ +S
Sbjct: 601 LDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVS 660
Query: 364 ASVPLEVTAPP 374
L V PP
Sbjct: 661 DEAELLVRGPP 671
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 132 bits (320), Expect = 6e-30
Identities = 111/398 (27%), Positives = 180/398 (45%), Gaps = 35/398 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F++ P E GE+AV C P I+W + +VI + R+ + N L
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQ 175
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + D+G + C + +A G+ + K ++IV PP + A N
Sbjct: 176 IRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN---------VPPTIQARQNIVNATAN 226
Query: 298 -ETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
SV C A GFP+P ++W +GE++ +E+ I + S L IK V +D Y
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWYRNT 411
C EN G+ A++ L+V A P V NQTA+ + + V TC+A G P PSI W +T
Sbjct: 287 CIAENKAGEQDATIHLKVFAKPKITYVE-NQTAMELEEQVTLTCEASGDPIPSITWRTST 345
Query: 412 VIL-----PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ + G++V+ + +LTL + D Y C A N G S L +V
Sbjct: 346 RNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL---EV 402
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
+ P + P + ++ V + CE+ + P A+I W +DG + + +I + +
Sbjct: 403 QYAPK--LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPS 460
Query: 525 IRNVSVT-----DTGRYECSAFNDYGRDTASVFLTVKD 557
+ VT D G Y C+A N G+++ L D
Sbjct: 461 ASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQAD 498
Score = 132 bits (319), Expect = 8e-30
Identities = 101/397 (25%), Positives = 177/397 (44%), Gaps = 37/397 (9%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAP-EILWLR-DSEVIPLNENRYEIFDN----GT 236
Q + P+ E+S GE+ F C G+ +I W + E + N+ R + N T
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSST 80
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L ++ AN +D G+++C+ G + + +K +P P F +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEF---------RE 131
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQ 354
E +V+ C P + W G ++L + R I+ N + I+ ++ +D G Y C+
Sbjct: 132 GEDAVIV-CDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE 190
Query: 355 VENI-HGKIS-ASVPLEVTAPPSFIVVP--TNQTAIIGDNVWFTCKAKGTPKPSIKWYRN 410
+ G+I+ + + V PP+ N TA +G +V C A+G P+P++ W ++
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKD 250
Query: 411 TVILPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
+ + + SDD+ LT+ +V ++D+A Y C AEN G +A T+
Sbjct: 251 GEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA----TIHLKVFA 306
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRI--------SITV 519
P+I E V + CE P SI WR I +++ S
Sbjct: 307 KPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ SL ++++ TD G Y C+A N G+D+ S++L V+
Sbjct: 367 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 403
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 132 bits (320), Expect = 6e-30
Identities = 111/398 (27%), Positives = 180/398 (45%), Gaps = 35/398 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F++ P E GE+AV C P I+W + +VI + R+ + N L
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQ 175
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + D+G + C + +A G+ + K ++IV PP + A N
Sbjct: 176 IRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN---------VPPTIQARQNIVNATAN 226
Query: 298 -ETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
SV C A GFP+P ++W +GE++ +E+ I + S L IK V +D Y
Sbjct: 227 LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWYRNT 411
C EN G+ A++ L+V A P V NQTA+ + + V TC+A G P PSI W +T
Sbjct: 287 CIAENKAGEQDATIHLKVFAKPKITYVE-NQTAMELEEQVTLTCEASGDPIPSITWRTST 345
Query: 412 VIL-----PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ + G++V+ + +LTL + D Y C A N G S L +V
Sbjct: 346 RNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL---EV 402
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
+ P + P + ++ V + CE+ + P A+I W +DG + + +I + +
Sbjct: 403 QYAPK--LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPS 460
Query: 525 IRNVSVT-----DTGRYECSAFNDYGRDTASVFLTVKD 557
+ VT D G Y C+A N G+++ L D
Sbjct: 461 ASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQAD 498
Score = 132 bits (319), Expect = 8e-30
Identities = 101/397 (25%), Positives = 177/397 (44%), Gaps = 37/397 (9%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAP-EILWLR-DSEVIPLNENRYEIFDN----GT 236
Q + P+ E+S GE+ F C G+ +I W + E + N+ R + N T
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSST 80
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L ++ AN +D G+++C+ G + + +K +P P F +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEF---------RE 131
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQ 354
E +V+ C P + W G ++L + R I+ N + I+ ++ +D G Y C+
Sbjct: 132 GEDAVIV-CDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE 190
Query: 355 VENI-HGKIS-ASVPLEVTAPPSFIVVP--TNQTAIIGDNVWFTCKAKGTPKPSIKWYRN 410
+ G+I+ + + V PP+ N TA +G +V C A+G P+P++ W ++
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKD 250
Query: 411 TVILPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
+ + + SDD+ LT+ +V ++D+A Y C AEN G +A T+
Sbjct: 251 GEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA----TIHLKVFA 306
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRI--------SITV 519
P+I E V + CE P SI WR I +++ S
Sbjct: 307 KPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ SL ++++ TD G Y C+A N G+D+ S++L V+
Sbjct: 367 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 403
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 132 bits (320), Expect = 6e-30
Identities = 111/398 (27%), Positives = 180/398 (45%), Gaps = 35/398 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F++ P E GE+AV C P I+W + +VI + R+ + N L
Sbjct: 197 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQ 256
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + D+G + C + +A G+ + K ++IV PP + A N
Sbjct: 257 IRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN---------VPPTIQARQNIVNATAN 307
Query: 298 -ETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
SV C A GFP+P ++W +GE++ +E+ I + S L IK V +D Y
Sbjct: 308 LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 367
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWYRNT 411
C EN G+ A++ L+V A P V NQTA+ + + V TC+A G P PSI W +T
Sbjct: 368 CIAENKAGEQDATIHLKVFAKPKITYVE-NQTAMELEEQVTLTCEASGDPIPSITWRTST 426
Query: 412 VIL-----PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ + G++V+ + +LTL + D Y C A N G S L +V
Sbjct: 427 RNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL---EV 483
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
+ P + P + ++ V + CE+ + P A+I W +DG + + +I + +
Sbjct: 484 QYAPK--LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPS 541
Query: 525 IRNVSVT-----DTGRYECSAFNDYGRDTASVFLTVKD 557
+ VT D G Y C+A N G+++ L D
Sbjct: 542 ASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQAD 579
Score = 132 bits (319), Expect = 8e-30
Identities = 101/397 (25%), Positives = 177/397 (44%), Gaps = 37/397 (9%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAP-EILWLR-DSEVIPLNENRYEIFDN----GT 236
Q + P+ E+S GE+ F C G+ +I W + E + N+ R + N T
Sbjct: 102 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSST 161
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L ++ AN +D G+++C+ G + + +K +P P F +
Sbjct: 162 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEF---------RE 212
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQ 354
E +V+ C P + W G ++L + R I+ N + I+ ++ +D G Y C+
Sbjct: 213 GEDAVIV-CDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE 271
Query: 355 VENI-HGKIS-ASVPLEVTAPPSFIVVP--TNQTAIIGDNVWFTCKAKGTPKPSIKWYRN 410
+ G+I+ + + V PP+ N TA +G +V C A+G P+P++ W ++
Sbjct: 272 GRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKD 331
Query: 411 TVILPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
+ + + SDD+ LT+ +V ++D+A Y C AEN G +A T+
Sbjct: 332 GEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA----TIHLKVFA 387
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRI--------SITV 519
P+I E V + CE P SI WR I +++ S
Sbjct: 388 KPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 447
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ SL ++++ TD G Y C+A N G+D+ S++L V+
Sbjct: 448 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 484
>BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein.
Length = 442
Score = 132 bits (319), Expect = 8e-30
Identities = 102/375 (27%), Positives = 164/375 (43%), Gaps = 31/375 (8%)
Query: 201 FTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNV 257
F C A G P+PE++W+ + P +R + NGTL + +D F C+A+N
Sbjct: 78 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 137
Query: 258 AGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW 317
G++ ++V+ + E P F + ++ S +C+ G P P + W
Sbjct: 138 GGES-----VLVVQLEVLEMLRR--PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 190
Query: 318 YF-NGERML---LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
NG R + + ++ NGS +I DAG Y C N G I V LE+
Sbjct: 191 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 250
Query: 374 PSFIV-VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT---VILP-ITGNLVLSDDNQN 428
P + P I G+++ C + G PKP+IKW + V P I G +L D N
Sbjct: 251 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGT 309
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQ 487
L + E T D Y C+A+N G + + + PPRI +P + + Q
Sbjct: 310 LVIKEATAYDRGNYICKAQNSVGH---TLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQ 366
Query: 488 MPCEIESVPPASIDWRKDGSRIVED---DRI----SITVIGSLIIRNVSVTDTGRYECSA 540
+ C VP I W ++ +R + + G+L+I+N +D+G Y+C+A
Sbjct: 367 LHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTA 426
Query: 541 FNDYGRDTASVFLTV 555
N G D A+ ++ V
Sbjct: 427 KNPLGSDYAATYIQV 441
Score = 107 bits (258), Expect = 2e-22
Identities = 90/347 (25%), Positives = 144/347 (41%), Gaps = 25/347 (7%)
Query: 221 VIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSP 280
+I + +RY NG+L +++ D G + C+A+N +G +K K+ V K
Sbjct: 1 MISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKLDVVSKPPLING- 58
Query: 281 APPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERML----LNERIILQHNG 336
++ + + + + FDC A G P P V W L RI + NG
Sbjct: 59 ---LYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNG 115
Query: 337 SILIKNVQNSDAGVYTCQVENIHGKISASVPLEV---TAPPSFIVVPTNQ--TAIIGDNV 391
++ I+NV+ SD+ + C N G+ V LEV P+F P N+ A +G +
Sbjct: 116 TLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTF-RNPFNEKIVAQLGKST 174
Query: 392 WFTCKAKGTPKPSIKWYRNTVILPITG---NLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C G P P I W G L N + + + TR+D Y C A N
Sbjct: 175 ALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARN 234
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR 508
G IE +L + Q +I + P + S+ + C + +P +I W
Sbjct: 235 KVGYIEKLVILEIGQKPVI---LTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGY 291
Query: 509 IVEDDRISITVI----GSLIIRNVSVTDTGRYECSAFNDYGRDTASV 551
+V+ +I+ I G+L+I+ + D G Y C A N G +V
Sbjct: 292 VVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITV 338
Score = 95.5 bits (227), Expect = 1e-18
Identities = 74/288 (25%), Positives = 121/288 (42%), Gaps = 26/288 (9%)
Query: 180 QQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN---ENRYEIFDNG 235
++P F + N+ + G++ C G P PEI+W+ + N +Y I NG
Sbjct: 154 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 213
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+ ++ + D G + C A+N G K+++ ++ PV ++
Sbjct: 214 SFIISKTTREDAGKYRCAARNKVGYIE----KLVILEIGQK------PVILTYAPGTVKG 263
Query: 296 INETSVMFDCTATGFPKPHVAWYFNG----ERMLLNERIILQHNGSILIKNVQNSDAGVY 351
I+ S+ C + G PKP++ W +R +N + IL NG+++IK D G Y
Sbjct: 264 ISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY 323
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
C+ +N G +VP+ + A P I P + G C A G PKP I W
Sbjct: 324 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM 383
Query: 410 NTVILPITGNLVLSDDNQNL----TLL--EVTRDDDAIYHCRAENDGG 451
L T + + ++ L TL+ D IY C A+N G
Sbjct: 384 PDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 431
Score = 89.0 bits (211), Expect = 1e-16
Identities = 72/243 (29%), Positives = 108/243 (44%), Gaps = 17/243 (6%)
Query: 328 ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA-PPSFIVVPTNQTAI 386
+R NGS+ I V+ D+G Y C N G + L+V + PP + TN+T I
Sbjct: 7 DRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVI 66
Query: 387 IGDNV-----WFTCKAKGTPKPSIKWYR-NTVIL--PITGNLVLSDDNQNLTLLEVTRDD 438
V F C+A+GTP P + W + + L P G+ + N L + V D
Sbjct: 67 KATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSD 126
Query: 439 DAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMDAFKETSVQMPCEIESVP 496
A + C A N+GG E+ V+ LE +E++ P E + A S + C ++ P
Sbjct: 127 SADFICVARNEGG--ESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNP 184
Query: 497 PASIDW-RKDGSRI---VEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVF 552
P I W +G+R + + I GS II + D G+Y C+A N G V
Sbjct: 185 PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVI 244
Query: 553 LTV 555
L +
Sbjct: 245 LEI 247
Score = 37.9 bits (84), Expect = 0.24
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 12/143 (8%)
Query: 426 NQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETS 485
N +LT+ +V D Y C A N G + + + L+ V PP I + K T+
Sbjct: 14 NGSLTINKVKLLDSGEYVCVARNPSG--DDTKMYKLDVVSK-PPLINGLYTNRTVIKATA 70
Query: 486 VQ-----MPCEIESVPPASIDWRKDGSRIVE----DDRISITVIGSLIIRNVSVTDTGRY 536
V+ C E P + W + + RI++ G+L IRNV ++D+ +
Sbjct: 71 VRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADF 130
Query: 537 ECSAFNDYGRDTASVFLTVKDNL 559
C A N+ G V L V + L
Sbjct: 131 ICVARNEGGESVLVVQLEVLEML 153
Score = 33.9 bits (74), Expect = 3.9
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 513 DRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV--KDNLLPGDAYVNIAL 570
DR + GSL I V + D+G Y C A N G DT L V K L+ G Y N +
Sbjct: 7 DRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLING-LYTNRTV 65
Query: 571 TQA 573
+A
Sbjct: 66 IKA 68
>AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens
cDNA FLJ25972 fis, clone TST05664. ).
Length = 399
Score = 132 bits (319), Expect = 8e-30
Identities = 102/375 (27%), Positives = 164/375 (43%), Gaps = 31/375 (8%)
Query: 201 FTCVATGEPAPEILWLRDSEVI---PLNENRYEIFDNGTLMVHEANENDDGLFECMAKNV 257
F C A G P+PE++W+ + P +R + NGTL + +D F C+A+N
Sbjct: 35 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNE 94
Query: 258 AGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAW 317
G++ ++V+ + E P F + ++ S +C+ G P P + W
Sbjct: 95 GGES-----VLVVQLEVLEMLRR--PTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW 147
Query: 318 YF-NGERML---LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAP 373
NG R + + ++ NGS +I DAG Y C N G I V LE+
Sbjct: 148 ILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQK 207
Query: 374 PSFIV-VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNT---VILP-ITGNLVLSDDNQN 428
P + P I G+++ C + G PKP+IKW + V P I G +L D N
Sbjct: 208 PVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHD-NGT 266
Query: 429 LTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKE-TSVQ 487
L + E T D Y C+A+N G + + + PPRI +P + + Q
Sbjct: 267 LVIKEATAYDRGNYICKAQNSVGH---TLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQ 323
Query: 488 MPCEIESVPPASIDWRKDGSRIVED---DRI----SITVIGSLIIRNVSVTDTGRYECSA 540
+ C VP I W ++ +R + + G+L+I+N +D+G Y+C+A
Sbjct: 324 LHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTA 383
Query: 541 FNDYGRDTASVFLTV 555
N G D A+ ++ V
Sbjct: 384 KNPLGSDYAATYIQV 398
Score = 95.5 bits (227), Expect = 1e-18
Identities = 74/288 (25%), Positives = 121/288 (42%), Gaps = 26/288 (9%)
Query: 180 QQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLN---ENRYEIFDNG 235
++P F + N+ + G++ C G P PEI+W+ + N +Y I NG
Sbjct: 111 RRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 170
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
+ ++ + D G + C A+N G K+++ ++ PV ++
Sbjct: 171 SFIISKTTREDAGKYRCAARNKVGYIE----KLVILEIGQK------PVILTYAPGTVKG 220
Query: 296 INETSVMFDCTATGFPKPHVAWYFNG----ERMLLNERIILQHNGSILIKNVQNSDAGVY 351
I+ S+ C + G PKP++ W +R +N + IL NG+++IK D G Y
Sbjct: 221 ISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNY 280
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIV--VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR 409
C+ +N G +VP+ + A P I P + G C A G PKP I W
Sbjct: 281 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEM 340
Query: 410 NTVILPITGNLVLSDDNQNL----TLL--EVTRDDDAIYHCRAENDGG 451
L T + + ++ L TL+ D IY C A+N G
Sbjct: 341 PDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 388
Score = 70.5 bits (165), Expect = 4e-11
Identities = 59/200 (29%), Positives = 89/200 (44%), Gaps = 16/200 (8%)
Query: 370 VTAPPSFIVVPTNQTAIIGDNV-----WFTCKAKGTPKPSIKWYR-NTVIL--PITGNLV 421
V+ PP + TN+T I V F C+A+GTP P + W + + L P G+ +
Sbjct: 7 VSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRI 66
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKP--EDMD 479
N L + V D A + C A N+GG E+ V+ LE +E++ P E +
Sbjct: 67 TVHKNGTLEIRNVRLSDSADFICVARNEGG--ESVLVVQLEVLEMLRRPTFRNPFNEKIV 124
Query: 480 AFKETSVQMPCEIESVPPASIDW-RKDGSRI---VEDDRISITVIGSLIIRNVSVTDTGR 535
A S + C ++ PP I W +G+R + + I GS II + D G+
Sbjct: 125 AQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGK 184
Query: 536 YECSAFNDYGRDTASVFLTV 555
Y C+A N G V L +
Sbjct: 185 YRCAARNKVGYIEKLVILEI 204
Score = 32.7 bits (71), Expect = 9.1
Identities = 22/84 (26%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 480 AFKETSVQMPCEIESVPPASIDWRKDGSRIVE----DDRISITVIGSLIIRNVSVTDTGR 535
A + + C E P + W + + RI++ G+L IRNV ++D+
Sbjct: 27 AVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSAD 86
Query: 536 YECSAFNDYGRDTASVFLTVKDNL 559
+ C A N+ G V L V + L
Sbjct: 87 FICVARNEGGESVLVVQLEVLEML 110
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 132 bits (319), Expect = 8e-30
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 19/384 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVI---PLNENRYEIFDNGTL 237
P F EP DV + G N C G P P I W R D+ I P + + G L
Sbjct: 134 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 193
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +D G + C A+N GK S+ + A P+ +P I
Sbjct: 194 FILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA--------PLIGISPSVANV-IE 244
Query: 298 ETSVMFDCTA-TGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVE 356
+ CT G P P W N +L N I ++ +GS+ I+ VQ D G YTC
Sbjct: 245 GQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVAS 304
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N+ G + + + V P+ + I G V CKA G PKPS+ W + ++
Sbjct: 305 NVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIST 364
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL-EQVEIIPPRIVL-- 473
+ + + +L ++ ++ Y C A N G + LT+ + + + L
Sbjct: 365 SSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQ 424
Query: 474 -KPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
KP ++ V +PCE++S+PP I W K+ I R + GS+ I +
Sbjct: 425 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTS 484
Query: 532 DTGRYECSAFNDYGRDTASVFLTV 555
D+G Y C A N G T +V L V
Sbjct: 485 DSGMYLCVATNIAGNVTQAVKLNV 508
Score = 130 bits (313), Expect = 4e-29
Identities = 92/329 (27%), Positives = 150/329 (45%), Gaps = 21/329 (6%)
Query: 234 NGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRF 293
+GTL + A D G++ C+A N AG + AP + V +
Sbjct: 4 DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE---------APKLMVVQSELLV 54
Query: 294 AKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHN--GSILIKNVQNSDAGVY 351
A + + +VM +C +G P P V W F G+ L ++ G + I+ Q+ DAG Y
Sbjct: 55 A-LGDITVM-ECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDY 111
Query: 352 TCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYR-- 409
TC N G+ + + L+V +PP FI P + + IG NV C +G P+P+IKW R
Sbjct: 112 TCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLD 171
Query: 410 NTVIL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
N I P + + + L +L + D Y C AEN G I++ +T+ ++
Sbjct: 172 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV--TGLV 229
Query: 468 PPRIVLKPEDMDAFKETSVQMPCE-IESVPPASIDWRKDGSRIVEDDRISITVIGSLIIR 526
P I + P + + + +PC + P W K+ + ++++ I++ GSL I
Sbjct: 230 APLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIE 289
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTV 555
V + D G Y C A N G + + + V
Sbjct: 290 RVQLQDGGEYTCVASNVAGTNNKTTSVVV 318
Score = 119 bits (287), Expect = 6e-26
Identities = 99/387 (25%), Positives = 159/387 (41%), Gaps = 29/387 (7%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDN--GTL 237
+ P+ +++ V+ G+ V C +G P P++ W + + L + + I D G L
Sbjct: 41 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD--LELRPSTFLIIDPLLGLL 98
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ E + D G + C+A N AG+A K + +PPVF+ P +I
Sbjct: 99 KIQETQDLDAGDYTCVAINEAGRATGKITLDV----------GSPPVFIQEPADVSMEIG 148
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLN-----ERIILQHNGSILIKNVQNSDAGVYT 352
++V C G+P+P + W + + I G++ I N+ SD G Y
Sbjct: 149 -SNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 207
Query: 353 CQVENIHGKISASVPLEVT--APPSFIVVPTNQTAIIGDNVWFTCK-AKGTPKPSIKWYR 409
C+ EN GKI + + VT P + P+ I G + C G P P +W +
Sbjct: 208 CEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIK 267
Query: 410 NTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPP 469
N+ +L + + D +L + V D Y C A N G T V + P
Sbjct: 268 NSAMLLQNPYITVRSDG-SLHIERVQLQDGGEYTCVASNVAGTNNK----TTSVVVHVLP 322
Query: 470 RIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRI-VEDDRISITVIGSLIIRNV 528
I + + + V +PC+ P S+ W K G I + S GSL + +
Sbjct: 323 TIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSP 382
Query: 529 SVTDTGRYECSAFNDYGRDTASVFLTV 555
++G Y C+A N G V LTV
Sbjct: 383 GGEESGEYVCTATNTAGYAKRKVQLTV 409
Score = 105 bits (251), Expect = 1e-21
Identities = 67/233 (28%), Positives = 111/233 (47%), Gaps = 11/233 (4%)
Query: 335 NGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFT 394
+G++ IKN DAG+Y C N G + L P +VV + +GD
Sbjct: 4 DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVME 63
Query: 395 CKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDA-IYHCRAENDGGMI 453
CK G P P +KW++ + L + L++ D L ++ T+D DA Y C A N+ G
Sbjct: 64 CKTSGIPPPQVKWFKGDLELRPSTFLII-DPLLGLLKIQETQDLDAGDYTCVAINEAG-- 120
Query: 454 EASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDD 513
A+ +TL+ PP + +P D+ ++V +PC ++ P +I WR+ + +
Sbjct: 121 RATGKITLDVGS--PPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSR 178
Query: 514 RISITVI-----GSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLP 561
S++ I G+L I N+ +D G Y C A N +G+ + +TV + P
Sbjct: 179 PFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 231
>AF267981-1|AAF78954.1| 1548|Homo sapiens putative NADPH
oxidase/peroxidase DUOX2 protein.
Length = 1548
Score = 131 bits (317), Expect = 1e-29
Identities = 112/389 (28%), Positives = 184/389 (47%), Gaps = 27/389 (6%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 169 RDLANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFP-RDSQNPLLMWAAPDP 227
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 228 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 286
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS F A+ +F +++ P
Sbjct: 287 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPP 342
Query: 1020 VLHRYDEN--FETIP----QGHLLLR--NAFF---SPWRLVDEGGVDPLLRGMFTTPAKL 1068
++ + + F + Q LR N ++ +P L V+ LL GM + ++L
Sbjct: 343 GVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENP-NLNSTQEVNELLLGMASQISEL 401
Query: 1069 KTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDL 1128
+ + + +L + D A +IQRGRD +P Y++ + ++ DL
Sbjct: 402 EDNI--VVEDLRDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDL 459
Query: 1129 SGEISDKEVRDKLQELYGS-VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGD 1187
+ + D +V + LY + +++ +GG+LE G GPLF ++++QFVRLRDGD
Sbjct: 460 NPNV-DPQVLEATAALYNQDLSQLELLLGGLLESH---GDPGPLFSAIVLDQFVRLRDGD 515
Query: 1188 RFWYENP--SVFKPDQLRQIKETSLARIL 1214
R+W+EN +F ++ I+ T+L +L
Sbjct: 516 RYWFENTRNGLFSKKEIEDIRNTTLRDVL 544
>AF230496-1|AAF73922.1| 1548|Homo sapiens NADPH thyroid oxidase 2
protein.
Length = 1548
Score = 131 bits (317), Expect = 1e-29
Identities = 112/389 (28%), Positives = 184/389 (47%), Gaps = 27/389 (6%)
Query: 840 REQINQLTSFLDASQVYGFEKSVAEDLRDLTNDNGLLRVGATFPGRKPLLPTSGFNGMDC 899
R+ NQ+T +LD S +YG S ++ LR + FP R P + D
Sbjct: 169 RDLANQVTGWLDGSAIYGSSHSWSDALRSFSGGQLASGPDPAFP-RDSQNPLLMWAAPDP 227
Query: 900 RRNLEESTRSCFVAGDIRANEQIGLAAMHTIWMREHNRIALQLKALNPFWDGDRVYQEAR 959
+ R + G R N + L A+ +W R HN A +L +P W+ + ++Q AR
Sbjct: 228 ATG-QNGPRGLYAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHAR 286
Query: 960 KVVGAQMQFITYEHWLPIILGPEGYDQLGKYKQYDNRLNPSISNVFATAALRFGHSLINP 1019
K V A Q I WLP L L +Y Y L+PSIS F A+ +F +++ P
Sbjct: 287 KRVIATYQNIAVYEWLPSFL----QKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPP 342
Query: 1020 VLHRYDEN--FETIP----QGHLLLR--NAFF---SPWRLVDEGGVDPLLRGMFTTPAKL 1068
++ + + F + Q LR N ++ +P L V+ LL GM + ++L
Sbjct: 343 GVYMRNASCHFRKVLNKGFQSSQALRVCNNYWIRENP-NLNSTQEVNELLLGMASQISEL 401
Query: 1069 KTSKQNLNSELTEKLFYSAHAVALDLAAINIQRGRDHAIPPYTKWRQFCNMSEVNDFDDL 1128
+ + + +L + D A +IQRGRD +P Y++ + ++ DL
Sbjct: 402 EDNI--VVEDLRDYWPGPGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDL 459
Query: 1129 SGEISDKEVRDKLQELYGS-VHNIDVWVGGILEDQVEGGKVGPLFRCLLMEQFVRLRDGD 1187
+ + D +V + LY + +++ +GG+LE G GPLF ++++QFVRLRDGD
Sbjct: 460 NPNV-DPQVLEATAALYNQDLSQLELLLGGLLESH---GDPGPLFSAIVLDQFVRLRDGD 515
Query: 1188 RFWYENP--SVFKPDQLRQIKETSLARIL 1214
R+W+EN +F ++ I+ T+L +L
Sbjct: 516 RYWFENTRNGLFSKKEIEDIRNTTLRDVL 544
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 131 bits (316), Expect = 2e-29
Identities = 104/413 (25%), Positives = 177/413 (42%), Gaps = 31/413 (7%)
Query: 111 SIPYGSFQGMPKLRKLRLDSNALICDCSILWFIRML-ENNEWMHVAATCYQPASVTGTSL 169
S+ +F M KL++L L++++L+CDC + W + + ENN V A+C P + G S+
Sbjct: 2 SLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSI 61
Query: 170 AAMKHHDLPCQ---QPQFESEPNDVEVSFGENAVFTC-VATGEPAP-EILWLRDSEVIP- 223
A+ C +PQ +P G N F C A+ +P W +D+E++
Sbjct: 62 FAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHD 121
Query: 224 --------LNENRYEIFDNGTLM-VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKA 274
L E+ + T++ + E +G ++C+ N G ++S AK+ V
Sbjct: 122 AEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNML- 180
Query: 275 EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNG--ERMLLNERI-- 330
P F TP + + + +C A G P P +AW +G + ER
Sbjct: 181 --------PSFTKTPMDLTIRAGAMARL-ECAAVGHPAPQIAWQKDGGTDFPAARERRMH 231
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDN 390
++ + I +V+ D GVY+C +N G ISA+ L V PSF+ ++T G+
Sbjct: 232 VMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGET 291
Query: 391 VWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDG 450
C A G+P P + W ++ L +T + NQ L +++ D Y C N
Sbjct: 292 AVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTL 351
Query: 451 GMIEASAVLTLEQVEII-PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDW 502
G + L++ P++ D D + V + + V S+ W
Sbjct: 352 GTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVW 404
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/231 (26%), Positives = 100/231 (43%), Gaps = 11/231 (4%)
Query: 331 ILQHNGSILIKNVQNSDAGVYTCQVENIHGK-ISASVPLEVTAPPSFIVVPTNQTAIIGD 389
++++ + ++ V+ + G Y C + N G S L V PSF P + T G
Sbjct: 137 VMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGA 196
Query: 390 NVWFTCKAKGTPKPSIKWYRNT-VILPITGN--LVLSDDNQNLTLLEVTRDDDAIYHCRA 446
C A G P P I W ++ P + + ++ +++V +D +Y C A
Sbjct: 197 MARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTA 256
Query: 447 ENDGGMIEASAVLT-LEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKD 505
+N G I A+A LT LE + P + D K + + C PP ++W KD
Sbjct: 257 QNSAGSISANATLTVLETPSFLRPLL-----DRTVTKGETAVLQCIAGGSPPPKLNWTKD 311
Query: 506 GSRIVEDDRISITVIGSL-IIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
S +V +R L II + V+D G+Y C N G + +V L+V
Sbjct: 312 DSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSV 362
>AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein
protein.
Length = 584
Score = 130 bits (315), Expect = 2e-29
Identities = 111/396 (28%), Positives = 164/396 (41%), Gaps = 38/396 (9%)
Query: 187 EPNDVEVSFGENAVFTCVATGEPAPEILW-LRDSEVIPL---------NENRYEIFDNGT 236
E ND +V +G + CVATG P PEI W L D ++ RY +F+NGT
Sbjct: 5 EENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGT 64
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L +E ++G + C A+N GK + +V A V Q + +
Sbjct: 65 LYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTCLAV-----QVPYGDV 119
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERML--LNERIILQHNGSILIKNVQNSDAGVYTCQ 354
V C A G P P V W +++ +E+ + +G++LI+ Q SD+G YTC
Sbjct: 120 ----VTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCL 175
Query: 355 VENIHGKISASVPLEVTAPPSFI------VVPTNQTAIIGDNVWFTCKAKGTPKPSIKW- 407
V N G+ +V + V P I + + A G CKA+G P P + W
Sbjct: 176 VRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWA 235
Query: 408 YRNTVILPIT--GNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
+ V+LP GN + N +L + + + D C A N+GG EA +L L +E
Sbjct: 236 FPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGG--EARLILQLTVLE 293
Query: 466 IIPPRIVLKP--EDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVED----DRISITV 519
+ I P E + A ++ + C P S+ W ++ R
Sbjct: 294 PMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 353
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
G L I +S D G Y C A N G V L V
Sbjct: 354 DGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKV 389
Score = 126 bits (303), Expect = 7e-28
Identities = 99/377 (26%), Positives = 160/377 (42%), Gaps = 24/377 (6%)
Query: 191 VEVSFGENAVFTCVATGEPAPEILWLRDS-EVIPLNENRYEIFDNGTLMVHEANENDDGL 249
V+V +G+ C A GEP P++ WL + +VIP + +Y+I+ +GTL++ +A +D G
Sbjct: 112 VQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGN 171
Query: 250 FECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATG 309
+ C+ +N AG+ + + + K P ++T ++ A + + DC A G
Sbjct: 172 YTCLVRNSAGEDRK---TVWIHVNVQPPKINGNPNPITTVREIAA--GGSRKLIDCKAEG 226
Query: 310 FPKPHVAWYFNGERML----LNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISAS 365
P P V W F +L RI + NGS+ I++++ SD+ C N G+
Sbjct: 227 IPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLI 286
Query: 366 VPLEVTAP---PSF-IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW-YRNTVILPITGNL 420
+ L V P P F + TA+ G + C A GTP PS+ W N L L
Sbjct: 287 LQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQL 346
Query: 421 --VLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
+ L + ++ D Y C A N G E L +V + P +
Sbjct: 347 QRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSL---KVGLKPEASKQYHNLV 403
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVED----DRISITVIGSLIIRNVSVTDTG 534
++++PC W +E R+S+ G+L +R SV D G
Sbjct: 404 SIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRG 463
Query: 535 RYECSAFNDYGRDTASV 551
Y C +YG S+
Sbjct: 464 TYVCRMETEYGPSVTSI 480
Score = 109 bits (263), Expect = 5e-23
Identities = 104/400 (26%), Positives = 165/400 (41%), Gaps = 34/400 (8%)
Query: 180 QQPQFESEPNDV----EVSFG-ENAVFTCVATGEPAPEILWLRDSEVI---PLNENRYEI 231
Q P+ PN + E++ G + C A G P P +LW V+ P NR +
Sbjct: 194 QPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV 253
Query: 232 FDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQK 291
NG+L + ++D CMA+N G+A ++I++ E P+F +
Sbjct: 254 HGNGSLDIRSLRKSDSVQLVCMARNEGGEA-----RLILQLTVLEPMEK--PIFHDPISE 306
Query: 292 RFAKINETSVMFDCTATGFPKPHVAWYF-NGERMLLNE---RIILQHNGSILIKNVQNSD 347
+ + ++ +C+A G P P + W NG + + R + +G + I + + D
Sbjct: 307 KITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 366
Query: 348 AGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAII-GDNVWFTCKAKGTPKPSIK 406
AG Y C N G V L+V P N +II G+ + C G +
Sbjct: 367 AGAYRCVARNAAGHTERLVSLKVGLKPEASKQYHNLVSIINGETLKLPCTPPGAGQGRFS 426
Query: 407 W-YRNTVIL--PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
W N + L P T V DN LT+ E + D Y CR E + G S +
Sbjct: 427 WTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVI--- 483
Query: 464 VEIIPPRIVLKPEDMDAFKE-TSVQMPCEIESVPPASIDWR-------KDGSRIVEDDRI 515
V PPRI +P + + +V++ C +P A I W K G +
Sbjct: 484 VIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNR 543
Query: 516 SITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
+ GSL I++ + D G Y+C A N G D+ + ++ V
Sbjct: 544 FLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHV 583
Score = 75.4 bits (177), Expect = 1e-12
Identities = 72/288 (25%), Positives = 116/288 (40%), Gaps = 28/288 (9%)
Query: 178 PCQQPQFESEPND-VEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF---D 233
P ++P F ++ + G C A G P P ++W+ + + + + F
Sbjct: 294 PMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKA 353
Query: 234 NGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRF 293
+G L + + D G + C+A+N AG + + V K E K V +
Sbjct: 354 DGMLHISGLSSVDAGAYRCVARNAAGHTE-RLVSLKVGLKPEASKQYHNLVSI------- 405
Query: 294 AKINETSVMFDCTATGFPKPHVAWYF-NGERMLLNE---RIILQHNGSILIKNVQNSDAG 349
IN ++ CT G + +W NG + + R+ L NG++ ++ D G
Sbjct: 406 --INGETLKLPCTPPGAGQGRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRG 463
Query: 350 VYTCQVENIHGKISASVPLEVTA-PPSFIVVPTNQT-AIIGDNVWFTCKAKGTPKPSIKW 407
Y C++E +G S+P+ V A PP PT G+ V C A G PK I W
Sbjct: 464 TYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITW 523
Query: 408 -------YRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
+ V + GN L +LT+ T+ D Y C A+N
Sbjct: 524 ELPDKSHLKAGVQARLYGNRFLHPQG-SLTIQHATQRDAGFYKCMAKN 570
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 130 bits (313), Expect = 4e-29
Identities = 104/374 (27%), Positives = 148/374 (39%), Gaps = 18/374 (4%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLR-DSEVIPLN-----ENRYEIFDNG 235
PQ P DV V G +A+ C ATG P P + W R D + + L +R D+G
Sbjct: 49 PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG 108
Query: 236 TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAK 295
L D + C A+NV GK ++ A++IV A P + S P R +
Sbjct: 109 VLFFESVAPEDQAPYVCEARNVFGKVQAE-ARLIVTGHAP------PQIASSAPTVRVLE 161
Query: 296 INETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQV 355
S+ A G P P W +G + R ++ +GS+ + AG Y+C
Sbjct: 162 GQPVSLPCIVLA-GRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVA 220
Query: 356 ENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILP 415
N G V L V PP T+ G C A G P P+I W + T L
Sbjct: 221 TNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALT 280
Query: 416 ITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS---AVLTLEQVEIIPPRIV 472
G L + + + D Y C A N G +V T ++ + R
Sbjct: 281 SRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNA 340
Query: 473 LKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGSLIIRNVSVT 531
P + A V + CE + PP + W KD + +R + GSL + V V
Sbjct: 341 DVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVG 400
Query: 532 DTGRYECSAFNDYG 545
D+G YEC+A N G
Sbjct: 401 DSGHYECTASNPAG 414
Score = 100 bits (240), Expect = 3e-20
Identities = 82/293 (27%), Positives = 118/293 (40%), Gaps = 27/293 (9%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVA-TGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVH 240
PQ S V V G+ C+ G P PE WL+D +P +R+ I +G+L +
Sbjct: 148 PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPG-SRHSIRADGSLHLD 206
Query: 241 EANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS 300
A + G + C+A N AG H + +++V+ PP T
Sbjct: 207 RALQEHAGRYSCVATNTAGSQH-RDVELVVQ---------VPPRIHPTATHHITN-EGVP 255
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNER---IILQHNGSILIKNVQNSDAGVYTCQVEN 357
C A+G P P + W E L R + G++LI DAG Y C N
Sbjct: 256 ASLPCVASGVPAPTITW--TKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATN 313
Query: 358 IHGKISASVPLEVTAPPSFIV-------VPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRN 410
G S + L V P + VP TA G+ V C+AKG+P P + W ++
Sbjct: 314 TVGFSSQEMRLSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKD 373
Query: 411 T-VILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
+ + PIT L +L L +V D Y C A N G VL ++
Sbjct: 374 SRPVPPITNRYGLLPSG-SLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQ 425
Score = 91.9 bits (218), Expect = 1e-17
Identities = 68/229 (29%), Positives = 95/229 (41%), Gaps = 9/229 (3%)
Query: 335 NGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFT 394
+G + I Q DAG YTC+ N G SA + L V P +P + T +G +
Sbjct: 10 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLA 69
Query: 395 CKAKGTPKPSIKWYR---NTVILPI---TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEN 448
C+A G P P++ W R + L + G+ D+ L V +D A Y C A N
Sbjct: 70 CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARN 129
Query: 449 DGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPC-EIESVPPASIDWRKDGS 507
G ++A A L + PP+I + + V +PC + P W KDG
Sbjct: 130 VFGKVQAEARLIV--TGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGR 187
Query: 508 RIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ R SI GSL + GRY C A N G V L V+
Sbjct: 188 PLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 236
Score = 87.4 bits (207), Expect = 3e-16
Identities = 84/333 (25%), Positives = 129/333 (38%), Gaps = 27/333 (8%)
Query: 234 NGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRF 293
+G L + A E D G + C A N G A ++ + A H P P+
Sbjct: 10 SGKLRIPAAQERDAGTYTCRAVNELGDASAEI------QLAVGHA----PQLTELPRDVT 59
Query: 294 AKINETSVMFDCTATGFPKPHVAWYF-NGERMLLN------ERIILQHNGSILIKNVQNS 346
++ S + C ATG P P V W +G+ + L R +G + ++V
Sbjct: 60 VELGR-SALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPE 118
Query: 347 DAGVYTCQVENIHGKISASVPLEVT--APPSFIVVPTNQTAIIGDNVWFTCKA-KGTPKP 403
D Y C+ N+ GK+ A L VT APP + G V C G P P
Sbjct: 119 DQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLP 178
Query: 404 SIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQ 463
W ++ LP + D +L L ++ Y C A N G L ++
Sbjct: 179 ERHWLKDGRPLPPGSRHSIRADG-SLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ- 236
Query: 464 VEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVE-DDRISITVIGS 522
+PPRI + +PC VP +I W K+ + + +++ G+
Sbjct: 237 ---VPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGT 293
Query: 523 LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
L+I S D G Y C+A N G + + L+V
Sbjct: 294 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSV 326
Score = 81.8 bits (193), Expect = 1e-14
Identities = 65/237 (27%), Positives = 99/237 (41%), Gaps = 12/237 (5%)
Query: 163 SVTGTSLAAMKHHDLPCQ---QPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDS 219
S T+ A +H D+ P+ + G A CVA+G PAP I W +++
Sbjct: 217 SCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKET 276
Query: 220 EVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKS 279
+ Y + GTL++ + + D G + C A N G + S+ ++ V K H +
Sbjct: 277 NALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFS-SQEMRLSVNTKPRIHMN 335
Query: 280 PAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERML-LNERIILQHNGSI 338
+ V P + AK E V DC A G P P V W + + + R L +GS+
Sbjct: 336 GSRNADV--PLQVTAKAGE-EVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSL 392
Query: 339 LIKNVQNSDAGVYTCQVENIHGKISASVPLEVTA----PPSFIVVPTNQTAIIGDNV 391
+ VQ D+G Y C N G S L V P + VP + + G +V
Sbjct: 393 RLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGRTSWQPQSLPVPHHPACLSGLSV 449
Score = 39.1 bits (87), Expect = 0.10
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 11/131 (8%)
Query: 438 DDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPP 497
D Y CRA N+ G +ASA + L P++ P D+ S + C PP
Sbjct: 22 DAGTYTCRAVNELG--DASAEIQLAVGHA--PQLTELPRDVTVELGRSALLACRATGRPP 77
Query: 498 ASIDWRK-DGSRIV------EDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTAS 550
++ WR+ DG + R G L +V+ D Y C A N +G+ A
Sbjct: 78 PTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAE 137
Query: 551 VFLTVKDNLLP 561
L V + P
Sbjct: 138 ARLIVTGHAPP 148
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 129 bits (311), Expect = 8e-29
Identities = 100/397 (25%), Positives = 176/397 (44%), Gaps = 37/397 (9%)
Query: 183 QFESEPNDVEVSFGENAVFTCVATGEPAP-EILWLR-DSEVIPLNENRYEIFDN----GT 236
Q + P+ E+S GE+ F C G+ +I W + E + N+ R + N T
Sbjct: 21 QVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSST 80
Query: 237 LMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKI 296
L ++ AN +D G+++C+ G + + +K +P P F +
Sbjct: 81 LTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEF---------RE 131
Query: 297 NETSVMFDCTATGFPKPHVAWYFNGERMLLNE--RIILQHNGSILIKNVQNSDAGVYTCQ 354
E +V+ C P + W G ++L + R I+ N + I+ ++ +D G Y C+
Sbjct: 132 GEDAVIV-CDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCE 190
Query: 355 VENI-HGKIS-ASVPLEVTAPPSFIVVP--TNQTAIIGDNVWFTCKAKGTPKPSIKWYRN 410
+ G+I+ + + V PP+ N TA +G +V C A+ P+P++ W ++
Sbjct: 191 GRILARGEINFKDIQVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKD 250
Query: 411 TVILPITGN---LVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEII 467
+ + + SDD+ LT+ +V ++D+A Y C AEN G +A T+
Sbjct: 251 GEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDA----TIHLKVFA 306
Query: 468 PPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRI--------SITV 519
P+I E V + CE P SI WR I +++ S
Sbjct: 307 KPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHAR 366
Query: 520 IGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ SL ++++ TD G Y C+A N G+D+ S++L V+
Sbjct: 367 VSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQ 403
Score = 128 bits (310), Expect = 1e-28
Identities = 110/398 (27%), Positives = 179/398 (44%), Gaps = 35/398 (8%)
Query: 180 QQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWL-RDSEVIPLNENRYEIFDNGTLM 238
Q+ F++ P E GE+AV C P I+W + +VI + R+ + N L
Sbjct: 116 QKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQ 175
Query: 239 VHEANENDDGLFECMAKNVA-GKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ + D+G + C + +A G+ + K ++IV PP + A N
Sbjct: 176 IRGIKKTDEGTYRCEGRILARGEINFKDIQVIVN---------VPPTIRARQNIVNATAN 226
Query: 298 -ETSVMFDCTATGFPKPHVAWYFNGERMLL---NERIILQHNGSIL-IKNVQNSDAGVYT 352
SV C A FP+P ++W +GE++ +E+ I + S L IK V +D Y
Sbjct: 227 LGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYI 286
Query: 353 CQVENIHGKISASVPLEVTAPPSFIVVPTNQTAI-IGDNVWFTCKAKGTPKPSIKWYRNT 411
C EN G+ A++ L+V A P V NQTA+ + + V TC+A G P PSI W +T
Sbjct: 287 CIAENKAGEQDATIHLKVFAKPKITYVE-NQTAMELEEQVTLTCEASGDPIPSITWRTST 345
Query: 412 VIL-----PITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQV 464
+ + G++V+ + +LTL + D Y C A N G S L +V
Sbjct: 346 RNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYL---EV 402
Query: 465 EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI 524
+ P + P + ++ V + CE+ + P A+I W +DG + + +I + +
Sbjct: 403 QYAPK--LQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPS 460
Query: 525 IRNVSVT-----DTGRYECSAFNDYGRDTASVFLTVKD 557
+ VT D G Y C+A N G+++ L D
Sbjct: 461 ASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQAD 498
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 128 bits (310), Expect = 1e-28
Identities = 80/297 (26%), Positives = 129/297 (43%), Gaps = 7/297 (2%)
Query: 184 FESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEAN 243
F P V A F C G PAP I W +D +P E R + NG L + +
Sbjct: 145 FSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQVTLP-EEPRLIVLPNGVLQILDVQ 203
Query: 244 ENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMF 303
E+D G + C+A N A + S+ A + V + + V + + ++ SV+
Sbjct: 204 ESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVM 263
Query: 304 DCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGK-- 361
+C A+ P P V+W + + + I+L ++LI N Q +GVY C+ +
Sbjct: 264 ECVASADPTPFVSWVRQDGKPISTDVIVLGRT-NLLIANAQPWHSGVYVCRANKPRTRDF 322
Query: 362 ISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLV 421
+A+ L V A P+ P + F C+A G P+P+++W N L G +
Sbjct: 323 ATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVK 382
Query: 422 LSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEAS---AVLTLEQVEIIPPRIVLKP 475
+ +L + ++ D Y C AEN GM A+ AV+ E + P R+ P
Sbjct: 383 VQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRVTATP 439
Score = 101 bits (241), Expect = 2e-20
Identities = 93/378 (24%), Positives = 153/378 (40%), Gaps = 29/378 (7%)
Query: 199 AVFTC---VATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEA---NENDDGLFEC 252
AV C A P + W +D + + L + + NG+L + + N +D+ + E
Sbjct: 53 AVLNCSLGAAAAGPPTRVTWSKDGDTL-LEHDHLHLLPNGSLWLSQPLAPNGSDESVPEA 111
Query: 253 MAK---NVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATG 309
+ N + AH P ++ + A K F P+ + + N T+ F+C G
Sbjct: 112 VGVIEGNYSCLAHG-PLGVLASQTAVV-KLATLADFSLHPESQTVEENGTA-RFECHIEG 168
Query: 310 FPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN-IHGKISASVPL 368
P P + W + + R+I+ NG + I +VQ SDAG Y C N S L
Sbjct: 169 LPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALL 228
Query: 369 EVTAPPSF----------IVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITG 418
V S + P N T + G +V C A P P + W R PI+
Sbjct: 229 SVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDG-KPIST 287
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDM 478
++++ NL + +Y CRA A+A L + P I PE +
Sbjct: 288 DVIVLG-RTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRV--LAAPAITQAPEAL 344
Query: 479 DAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIG-SLIIRNVSVTDTGRYE 537
+ ++ + C P ++ W +G+ + + R+ + G SL+I + + D G Y+
Sbjct: 345 SRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQ 404
Query: 538 CSAFNDYGRDTASVFLTV 555
C A N G A+ L V
Sbjct: 405 CVAENSAGMACAAASLAV 422
Score = 68.5 bits (160), Expect = 1e-10
Identities = 73/280 (26%), Positives = 115/280 (41%), Gaps = 32/280 (11%)
Query: 298 ETSVMFDCT---ATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNV---QNSDAGV- 350
E + + +C+ A P V W +G+ +L ++ + L NGS+ + SD V
Sbjct: 50 EQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAPNGSDESVP 109
Query: 351 ---------YTCQVENIHGKI-SASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGT 400
Y+C G + S + +++ F + P +QT F C +G
Sbjct: 110 EAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGL 169
Query: 401 PKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGM-IEASAVL 459
P P I W ++ V LP L++ N L +L+V D Y C A N A+L
Sbjct: 170 PAPIITWEKDQVTLPEEPRLIVL-PNGVLQILDVQESDAGPYRCVATNSARQHFSQEALL 228
Query: 460 TL-EQVEIIPPR-----IVLKPEDMDAFKETSVQMPCEIESVPPASIDW-RKDGSRIVED 512
++ + + R IV PE+ SV M C + P + W R+DG I D
Sbjct: 229 SVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTD 288
Query: 513 DRISITVIG--SLIIRNVSVTDTGRYECSAFNDYGRDTAS 550
+ V+G +L+I N +G Y C A RD A+
Sbjct: 289 ----VIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFAT 324
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 3/108 (2%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHE 241
P P + + A F C A+GEP P + WL + + N G+L++ +
Sbjct: 335 PAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQ 394
Query: 242 ANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTP 289
D G ++C+A+N AG A + + +V R E AP +TP
Sbjct: 395 IGLQDAGYYQCVAENSAGMACAAASLAVVVR---EGLPSAPTRVTATP 439
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 128 bits (309), Expect = 1e-28
Identities = 102/406 (25%), Positives = 166/406 (40%), Gaps = 34/406 (8%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNG---TLM 238
P+FES+P EV + F C +G P PE+ W + + E E+++N L
Sbjct: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLC 473
Query: 239 VHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINE 298
+ +A D G + C A N G+ S + V R A +P+ S+ K A I
Sbjct: 474 LLKARTRDSGTYSCTASNAQGQV-SCSWTLQVERLAVMEVAPS----FSSVLKDCAVIEG 528
Query: 299 TSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENI 358
+ C+ G P P + W NG+ + + I++ D G YTC EN
Sbjct: 529 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
Query: 359 HGKISASVPLEVTAPPS-------FIVVPTNQTAII------------GDNVWFTCKAKG 399
G++S S + V S V P+ TA I G V T + G
Sbjct: 589 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
Query: 400 TPKPSIKWYRNTVILPITGNLVLSD--DNQNLTLLEVTRDDDAIYHCRAENDGGMIEASA 457
P P + W N + + + +L + EV +D Y C A N G + A
Sbjct: 649 NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
Query: 458 VLTLEQV-EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVED---- 512
VLT+++ + P + KP + A SV + C I P ++ W +DG + +D
Sbjct: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768
Query: 513 DRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKDN 558
+ + + +L+++ V G+YE N G + V L ++++
Sbjct: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
Score = 113 bits (271), Expect = 5e-24
Identities = 89/311 (28%), Positives = 132/311 (42%), Gaps = 30/311 (9%)
Query: 275 EEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERII--L 332
E + A P F S PQ + K N+T V F C +G PKP VAW+ G + E I
Sbjct: 406 EGQRDSAFPKFESKPQSQEVKENQT-VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
Query: 333 QHNGS--ILIKNVQNSDAGVYTCQVENIHGKISASVPLEVT------APPSFIVVPTNQT 384
++ GS + + + D+G Y+C N G++S S L+V PSF V +
Sbjct: 465 ENAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
Query: 385 AIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHC 444
I G + C +GTP P I W N + + + + L + + +D Y C
Sbjct: 525 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTC 583
Query: 445 RAENDGGMIEASAVLTLEQV------EIIPPRIVLKP---------EDMDAFKETSVQMP 489
AEN G + SA +T+ + E + P KP D+ + V M
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 490 CEIESVPPASIDWRKDGSRIVEDDRISITVIG---SLIIRNVSVTDTGRYECSAFNDYGR 546
++ PP + W +G+ I E + G SL I+ V DTG Y C A+N G
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
Query: 547 DTASVFLTVKD 557
LTV++
Sbjct: 704 VRTQAVLTVQE 714
Score = 63.3 bits (147), Expect = 6e-09
Identities = 62/240 (25%), Positives = 96/240 (40%), Gaps = 34/240 (14%)
Query: 163 SVTGTSLAAMKHHDLPCQQ-PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEV 221
S T S+ + +P + P F P ++ + G A F G P P++ W R+ +
Sbjct: 13 SKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQ- 71
Query: 222 IPLNENRYEIFDNG-----TLMVHEANENDDGLFECMAKNVAG---------------KA 261
P+ + D G +L++H +E D G + C A N +G K
Sbjct: 72 -PITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQ 130
Query: 262 HSKP--AKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVM------FDCTATGFPKP 313
+P +K + R + P ++ P K K+ V F C TG P+P
Sbjct: 131 LGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
Query: 314 HVAWYFNGERMLLNERI-ILQHNGS--ILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
V W + + R+ + + NG + I V D GVYTC V N GK S S L +
Sbjct: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 56.0 bits (129), Expect = 9e-07
Identities = 31/113 (27%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 165 TGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
T L + HD QP F S+P V S G++ + +C G+P P + WLRD + +
Sbjct: 706 TQAVLTVQEPHD--GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
Query: 225 NENRYEIFDNG---TLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKA 274
+ +E+ N TL++ + G +E + KN G+ + + M+ A
Sbjct: 764 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 178 PCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNEN---RYEIFDN 234
P +P F D+EV G A F C G P PE++W +D + I + + Y+ N
Sbjct: 1805 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1864
Query: 235 GTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAE 275
+L++ + +DD + C A N G+A + A++IV E
Sbjct: 1865 CSLIISDVCGDDDAKYTCKAVNSLGEA-TCTAELIVETMEE 1904
Score = 50.0 bits (114), Expect = 6e-05
Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 7/126 (5%)
Query: 255 KNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPH 314
K VA SK + + + + P F+ P+ K T+ F+ G+P+P
Sbjct: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATA-KFEGRVRGYPEPQ 63
Query: 315 VAWYFNGERMLLNERIIL----QHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
V W+ NG+ + R +L + S++I V D G YTC+ N G + V +E+
Sbjct: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVEL 121
Query: 371 TAPPSF 376
T SF
Sbjct: 122 TVEGSF 127
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 2/95 (2%)
Query: 373 PPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDN--QNLT 430
PP F G F+CK G P+P + W + V L + + +S+ N Q L
Sbjct: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
+ V +DD +Y C N G SA L+++ ++
Sbjct: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
Score = 46.8 bits (106), Expect = 5e-04
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 374 PSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS---DDNQNLT 430
P F + + G F CK +G P P + W+++ + + + + D N +L
Sbjct: 1809 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1868
Query: 431 LLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVE 465
+ +V DDDA Y C+A N G +A L +E +E
Sbjct: 1869 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1903
Score = 46.4 bits (105), Expect = 7e-04
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 365 SVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLS- 423
S+PL T P+FI+ P N G F + +G P+P + W+RN + G +L
Sbjct: 26 SMPL--TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
Query: 424 --DDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLE 462
+L + V +D Y C A N G + + LT+E
Sbjct: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 45.2 bits (102), Expect = 0.002
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
Query: 469 PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLI---I 525
P K +D+ + + + C++ S PPA+I W +G + I ++ GSL I
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
Query: 526 RNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
D G Y+C A ND G+ S +TV D
Sbjct: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
Score = 44.4 bits (100), Expect = 0.003
Identities = 35/136 (25%), Positives = 60/136 (44%), Gaps = 9/136 (6%)
Query: 182 PQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIF-DNGTL--- 237
P F+ + DV V+ G+ + C + +P I+W + + L ++ I G+L
Sbjct: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT--LKTTKFIILSQEGSLCSV 1155
Query: 238 MVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKIN 297
+ +A D GL++C+AKN AG+A + A E+ + AP + P+ +
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN-TKAPEMKSRRPKSSLPPVL 1214
Query: 298 ETSVMFDCTATGFPKP 313
T D T P P
Sbjct: 1215 GTE--SDATVKKKPAP 1228
Score = 43.6 bits (98), Expect = 0.005
Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 4/116 (3%)
Query: 445 RAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRK 504
+ E++ + +A E+ + P D++ + ++ + C+IE P + W K
Sbjct: 1785 KLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 1844
Query: 505 DGSRIVEDDRISITVIG----SLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
D I E I SLII +V D +Y C A N G T + L V+
Sbjct: 1845 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1900
Score = 42.3 bits (95), Expect = 0.011
Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 5/99 (5%)
Query: 276 EHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQH- 334
E K P F T + + ++ FDC G+P P V W+ + + + + + +
Sbjct: 1802 EEKPHVKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860
Query: 335 ---NGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEV 370
N S++I +V D YTC+ N G+ + + L V
Sbjct: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1899
Score = 39.9 bits (89), Expect = 0.060
Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
Query: 469 PRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISIT--VIG--SLI 524
P +L P ++ + + + + P + W ++G I R + + G SL+
Sbjct: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
Query: 525 IRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
I V D G+Y C A N G +V LTV+
Sbjct: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 39.9 bits (89), Expect = 0.060
Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query: 388 GDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQ--NLTLLEVTRDDDAIYHCR 445
G + C+ P +I W N L T ++LS + ++++ + +D +Y C
Sbjct: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
Query: 446 AENDGGMIEASAVLTLE 462
A+ND G E S +T++
Sbjct: 1172 AKNDAGQAECSCQVTVD 1188
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 301 VMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNS---DAGVYTCQVEN 357
++ C + P + W NG+ + + IIL GS+ +++ + D G+Y C +N
Sbjct: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
Query: 358 IHGKISASVPLEVTAPPS 375
G+ S + V P+
Sbjct: 1175 DAGQAECSCQVTVDDAPA 1192
Score = 33.9 bits (74), Expect = 3.9
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 3/94 (3%)
Query: 467 IPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISI--TVIGS-L 523
+PP+I+ PED SV++ ++ P + W K +I E + + + + GS L
Sbjct: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
Query: 524 IIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I G Y N G A V LTV D
Sbjct: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
Score = 33.5 bits (73), Expect = 5.2
Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 4/111 (3%)
Query: 450 GGMIEASAVLTLEQV-EIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR 508
G ASAV T + PP+ K + + + C+I P + W K
Sbjct: 141 GDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
Query: 509 IVEDDRISITVIGS---LIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVK 556
+ R+S++ L I V+ D G Y C N G+ + S L+++
Sbjct: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 33.1 bits (72), Expect = 6.9
Identities = 25/103 (24%), Positives = 41/103 (39%), Gaps = 2/103 (1%)
Query: 361 KISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKW--YRNTVILPITG 418
K + P + PP I P +Q G++V K GT + W +R +
Sbjct: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
Query: 419 NLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+ S++ LT+L ++ Y EN G +A LT+
Sbjct: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
>AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar to
hemicentin (LOC392395) protein.
Length = 746
Score = 128 bits (309), Expect = 1e-28
Identities = 89/297 (29%), Positives = 136/297 (45%), Gaps = 20/297 (6%)
Query: 165 TGTSLAAMKHHDLPCQQPQFESEPNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPL 224
TG + A + D P PQ PN V VS GE AV +C GE + W+RD V+P
Sbjct: 467 TGRAKAQIVVTDPP---PQLVPAPN-VTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPA 522
Query: 225 NENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPV 284
+ R + +L + D G ++C+A N G + ++VR AP V
Sbjct: 523 STGRVAQLADLSLEISGIIPTDGGRYQCVASNANGVTRAS-VWLLVRE--------APQV 573
Query: 285 FVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQ 344
+ T + F++ E V C+A+G+P PH++W + + + RI + G+++I+ V
Sbjct: 574 SIHTSSQHFSQGVEVKV--SCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVA 631
Query: 345 NSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPS 404
DAG Y+CQ N G +V L T PPS V +G+ C+A G P P
Sbjct: 632 PEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPR 691
Query: 405 IKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTL 461
+ WYR + + + + L + D Y CRA N+ G +ASA + L
Sbjct: 692 VIWYRGGLEMILAPE---GSSSGKLRIPAAQERDAGTYTCRAVNELG--DASAEIQL 743
Score = 101 bits (241), Expect = 2e-20
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 5/238 (2%)
Query: 321 GERMLLNERIILQH-NGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVV 379
GE L ER + N S I ++ G Y C + G A + VT PP +V
Sbjct: 426 GEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQLVP 485
Query: 380 PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD 439
N T G+ +C+ G ++ W R+ +LP + V + +L + + D
Sbjct: 486 APNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDG 545
Query: 440 AIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPAS 499
Y C A N G+ AS L + + P++ + + V++ C P
Sbjct: 546 GRYQCVASNANGVTRASVWLLVREA----PQVSIHTSSQHFSQGVEVKVSCSASGYPTPH 601
Query: 500 IDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTVKD 557
I W ++ + ED RI + G+LII+ V+ D G Y C A N+ G D +V L D
Sbjct: 602 ISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 659
Score = 93.5 bits (222), Expect = 5e-18
Identities = 92/347 (26%), Positives = 146/347 (42%), Gaps = 21/347 (6%)
Query: 211 PEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKNVAGKAHSKPAKMIV 270
P L LR E E ++ N + + A++ ++G +EC A + AG +K A+++V
Sbjct: 418 PFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTGRAK-AQIVV 476
Query: 271 RRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPKPHVAWYFNGERMLLNE-R 329
+ PAP V VS ET+V+ C G ++ W + + + R
Sbjct: 477 TDPPPQ-LVPAPNVTVSP--------GETAVL-SCRVLGEAPYNLTWVRDWRVLPASTGR 526
Query: 330 IILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPSFIVVPTNQTAIIGD 389
+ + S+ I + +D G Y C N +G ASV L V P + ++Q G
Sbjct: 527 VAQLADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGV 586
Query: 390 NVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAEND 449
V +C A G P P I W R + L + + D L + V +D Y C+A N+
Sbjct: 587 EVKVSCSASGYPTPHISWSRESQALQEDSRIHV-DAQGTLIIQGVAPEDAGNYSCQATNE 645
Query: 450 GGMIEASAVLTLEQVEIIPPRI-VLKPEDMDAFKETSVQMPCEIESVPPASIDWRKDGSR 508
G + + L PP + + + A E +V + CE VPP + W + G
Sbjct: 646 VGTDQETVTLYYTD----PPSVSAVNAVVLVAVGEEAV-LVCEASGVPPPRVIWYRGGLE 700
Query: 509 IVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
++ S + G L I D G Y C A N+ G +A + L V
Sbjct: 701 MILAPEGSSS--GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 745
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 127 bits (306), Expect = 3e-28
Identities = 104/373 (27%), Positives = 166/373 (44%), Gaps = 36/373 (9%)
Query: 181 QPQFESE-PNDVEVSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMV 239
+P+ E P V + G C A G P P I W++ + IP + L +
Sbjct: 5 EPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRK--SQAVLEI 62
Query: 240 HEANENDDGLFECMAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINET 299
+D G++EC A+N GK + + K + +P +
Sbjct: 63 PNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLR-------- 114
Query: 300 SVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIH 359
++C ATG P+P W NG + R+ + NG ++I NV SDAG+Y C EN +
Sbjct: 115 ---WECKATGKPRPTYRWLKNGVPLSPQSRVEMV-NGVLMIHNVNQSDAGMYQCLAENKY 170
Query: 360 GKISASVPLEVTAP-PSFIVVPTNQTAII--GDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
G I AS L++ A P+F + +T I+ V CK +G+PKP+I W + +
Sbjct: 171 GAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRE 230
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPE 476
+ + D +L +L ++ D+ Y CR EN G E A L++++ P RI L P+
Sbjct: 231 NKRIAILPDG-SLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE----PTRIELTPK 285
Query: 477 DMDAFKETSVQMPCEIESVPPASID----WRKDGSRIVEDDR----ISITVIGS---LII 525
+ S+ + C+ ++ AS+D W G I ++ SI S L+I
Sbjct: 286 RTELTVGESIVLNCK--AIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 343
Query: 526 RNVSVTDTGRYEC 538
RN+ + GRY C
Sbjct: 344 RNILLMHAGRYGC 356
Score = 120 bits (290), Expect = 3e-26
Identities = 83/263 (31%), Positives = 128/263 (48%), Gaps = 12/263 (4%)
Query: 299 TSVMFDCTATGFPKPHVAWY-FNGERMLLNERIILQHNGSIL-IKNVQNSDAGVYTCQVE 356
T+V +C A G P P + W NG + + L+ + ++L I NVQ DAG+Y C+ E
Sbjct: 22 TTVKMECFALGNPVPTITWMKVNG---YIPSKARLRKSQAVLEIPNVQLDDAGIYECRAE 78
Query: 357 NIHGKISASVPLEVTAPPSFIVVPTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPI 416
N GK S L+V P ++ + G + + CKA G P+P+ +W +N V P+
Sbjct: 79 NSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV--PL 136
Query: 417 TGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK-- 474
+ + N L + V + D +Y C AEN G I ASA L ++ P L
Sbjct: 137 SPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAEL---KILASAPTFALNQL 193
Query: 475 PEDMDAFKETSVQMPCEIESVPPASIDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTG 534
+ + K+ V + C+ + P +I W+K + E+ RI+I GSL I N S +D G
Sbjct: 194 KKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEG 253
Query: 535 RYECSAFNDYGRDTASVFLTVKD 557
+Y C N +G L+VK+
Sbjct: 254 KYVCRGENVFGSAEIIASLSVKE 276
Score = 74.1 bits (174), Expect = 3e-12
Identities = 55/176 (31%), Positives = 74/176 (42%), Gaps = 7/176 (3%)
Query: 380 PTNQTAIIGDNVWFTCKAKGTPKPSIKWYRNTVILPITGNLVLSDDNQNLTLLEVTRDDD 439
P TA G V C A G P P+I W + +P L S L + V DD
Sbjct: 13 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKS--QAVLEIPNVQLDDA 70
Query: 440 AIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLKPEDMDAFKETSVQMPCEIESVPPAS 499
IY CRAEN G L + P V K D + ++ C+ P +
Sbjct: 71 GIYECRAENSRGKNSFRGQLQVYTY----PHWVEKLNDTQLDSGSPLRWECKATGKPRPT 126
Query: 500 IDWRKDGSRIVEDDRISITVIGSLIIRNVSVTDTGRYECSAFNDYGRDTASVFLTV 555
W K+G + R+ + V G L+I NV+ +D G Y+C A N YG AS L +
Sbjct: 127 YRWLKNGVPLSPQSRVEM-VNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKI 181
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/191 (24%), Positives = 84/191 (43%), Gaps = 21/191 (10%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFEC 252
V+ + V C G P P I W + + N+ R I +G+L + A+++D+G + C
Sbjct: 199 VTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVC 257
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+NV G A ++I +E P TP++ + E S++ +C A
Sbjct: 258 RGENVFGSA-----EIIASLSVKE-----PTRIELTPKRTELTVGE-SIVLNCKAIHDAS 306
Query: 313 PHVAWYFNGERMLLN--------ERIILQHNGS-ILIKNVQNSDAGVYTCQVENIHGKIS 363
V +Y+ + ++ E I Q + + ++I+N+ AG Y C+V+ +S
Sbjct: 307 LDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVS 366
Query: 364 ASVPLEVTAPP 374
L V PP
Sbjct: 367 DEAELLVRGPP 377
>BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein.
Length = 697
Score = 126 bits (305), Expect = 4e-28
Identities = 86/278 (30%), Positives = 131/278 (47%), Gaps = 17/278 (6%)
Query: 298 ETSVMFDCTATGFPKPHVAWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVEN 357
E +V ++C A G PKP W NGE +L +RI ++ G++ I V SDAG+Y C EN
Sbjct: 2 EENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIE-QGTLNITIVNLSDAGMYQCLAEN 60
Query: 358 IHGKISASVPLEVTA-PPSFIVVPTNQTAI--IGDNVWFTCKAKGTPKPSIKWYRNTVIL 414
HG I ++ L V A P F + + +G V CK K +PKP W + IL
Sbjct: 61 KHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 120
Query: 415 PITGNLVLSDDNQNLTLLEVTRDDDAIYHCRAENDGGMIEASAVLTLEQVEIIPPRIVLK 474
+ +S+D NL ++ VT+ D Y C A N G ++ L ++ P R+++
Sbjct: 121 KENERITISEDG-NLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKD----PTRVMVP 175
Query: 475 PEDMDAFKETSVQMPCEIESVPPASI--DWRKDGSRIVED------DRISITVIGSLIIR 526
P MD S+ +PC++ I W +G I D +R+ G L+IR
Sbjct: 176 PSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGDSAGDLMIR 235
Query: 527 NVSVTDTGRYECSAFNDYGRDTASVFLTVKDNLLPGDA 564
N+ + G+Y C R +A+ L V+ P +A
Sbjct: 236 NIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEA 273
Score = 96.7 bits (230), Expect = 5e-19
Identities = 61/201 (30%), Positives = 96/201 (47%), Gaps = 12/201 (5%)
Query: 197 ENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFECMAKN 256
EN + C A G P P WL++ E + L +R +I + GTL + N +D G+++C+A+N
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGEPL-LTRDRIQI-EQGTLNITIVNLSDAGMYQCLAEN 60
Query: 257 VAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETS-VMFDCTATGFPKPHV 315
G ++ AE P F T KR + V+ +C PKP
Sbjct: 61 KHG---------VIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVY 111
Query: 316 AWYFNGERMLLNERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISASVPLEVTAPPS 375
W + + NERI + +G++ I NV SDAG YTC N G S++ L V P
Sbjct: 112 TWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTR 171
Query: 376 FIVVPTNQTAIIGDNVWFTCK 396
+V P++ +G+++ C+
Sbjct: 172 VMVPPSSMDVTVGESIVLPCQ 192
Score = 62.5 bits (145), Expect = 1e-08
Identities = 49/190 (25%), Positives = 77/190 (40%), Gaps = 20/190 (10%)
Query: 193 VSFGENAVFTCVATGEPAPEILWLRDSEVIPLNENRYEIFDNGTLMVHEANENDDGLFEC 252
V G V C P P W + +++ NE R I ++G L + ++D G + C
Sbjct: 91 VKVGGEVVIECKPKASPKPVYTWKKGRDILKENE-RITISEDGNLRIINVTKSDAGSYTC 149
Query: 253 MAKNVAGKAHSKPAKMIVRRKAEEHKSPAPPVFVSTPQKRFAKINETSVMFDCTATGFPK 312
+A N G A S ++V+ P V P S++ C T
Sbjct: 150 IATNHFGTA-SSTGNLVVK----------DPTRVMVPPSSMDVTVGESIVLPCQVTHDHS 198
Query: 313 PHVA--WYFNGERMLLN------ERIILQHNGSILIKNVQNSDAGVYTCQVENIHGKISA 364
+ W FNG + + ER+ G ++I+N+Q AG Y C V+ ++SA
Sbjct: 199 LDIVFTWSFNGHLIDFDRDGDHFERVGGDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSA 258
Query: 365 SVPLEVTAPP 374
+ L V PP
Sbjct: 259 AADLIVRGPP 268
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.137 0.420
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 197,739,710
Number of Sequences: 224733
Number of extensions: 8596310
Number of successful extensions: 54245
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1468
Number of HSP's successfully gapped in prelim test: 887
Number of HSP's that attempted gapping in prelim test: 27777
Number of HSP's gapped (non-prelim): 12859
length of query: 1329
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1230
effective length of database: 50,986,271
effective search space: 62713113330
effective search space used: 62713113330
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
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