BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000550-TA|BGIBMGA000550-PA|undefined (1178 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BC060759-1|AAH60759.1| 1359|Homo sapiens CRSP3 protein protein. 1170 0.0 AL121575-7|CAB92072.1| 1368|Homo sapiens cofactor required for S... 1170 0.0 AL121575-5|CAI23320.1| 1364|Homo sapiens cofactor required for S... 1170 0.0 AB033042-1|BAA86530.1| 1421|Homo sapiens KIAA1216 protein protein. 1170 0.0 AF105332-1|AAD31729.1| 1368|Homo sapiens vitamin D3 receptor int... 1170 0.0 AF135022-1|AAD30202.1| 1364|Homo sapiens mediator protein. 1164 0.0 AL121575-6|CAI23321.1| 1374|Homo sapiens cofactor required for S... 1162 0.0 AL121575-4|CAI23319.1| 1365|Homo sapiens cofactor required for S... 1162 0.0 AL121575-8|CAB92073.1| 886|Homo sapiens cofactor required for S... 803 0.0 AF104255-1|AAD12724.1| 936|Homo sapiens transcriptional co-acti... 803 0.0 >BC060759-1|AAH60759.1| 1359|Homo sapiens CRSP3 protein protein. Length = 1359 Score = 1170 bits (2899), Expect = 0.0 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 318 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 378 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + PMG + Sbjct: 438 NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 496 VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 556 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 612 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 672 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 732 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 792 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 852 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR +PVFDIV Sbjct: 911 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 971 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AL121575-7|CAB92072.1| 1368|Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa protein. Length = 1368 Score = 1170 bits (2899), Expect = 0.0 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 318 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 378 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + PMG + Sbjct: 438 NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 496 VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 556 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 612 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 672 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 732 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 792 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 852 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR +PVFDIV Sbjct: 911 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 971 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AL121575-5|CAI23320.1| 1364|Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa protein. Length = 1364 Score = 1170 bits (2899), Expect = 0.0 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 318 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 378 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + PMG + Sbjct: 438 NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 496 VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 556 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 612 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 672 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 732 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 792 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 852 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR +PVFDIV Sbjct: 911 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 971 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AB033042-1|BAA86530.1| 1421|Homo sapiens KIAA1216 protein protein. Length = 1421 Score = 1170 bits (2899), Expect = 0.0 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 254 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 310 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 311 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 370 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 371 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 430 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 431 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 490 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + PMG + Sbjct: 491 NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 548 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 549 VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 608 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 609 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 664 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 665 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 724 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 725 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 784 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 785 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 844 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 845 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 904 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 905 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 963 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR +PVFDIV Sbjct: 964 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 1023 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 1024 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1083 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1084 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1130 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1131 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1190 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1191 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1250 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1251 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1281 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1351 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1389 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 148 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 200 >AF105332-1|AAD31729.1| 1368|Homo sapiens vitamin D3 receptor interacting protein protein. Length = 1368 Score = 1170 bits (2898), Expect = 0.0 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 318 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 378 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + PMG + Sbjct: 438 NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 496 VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 556 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 612 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 672 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 732 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 792 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 852 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAP-------IPVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P +P+Y NVCLR +PVFDIV Sbjct: 911 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPCTDPVSYLPIYFGNVCLRFLPVFDIV 970 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 971 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336 Score = 52.4 bits (120), Expect = 9e-06 Identities = 22/53 (41%), Positives = 37/53 (69%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVD KGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDNKGVRDLLKVILEKILT 147 >AF135022-1|AAD30202.1| 1364|Homo sapiens mediator protein. Length = 1364 Score = 1164 bits (2884), Expect = 0.0 Identities = 565/1051 (53%), Positives = 746/1051 (70%), Gaps = 44/1051 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ V++ +P A++ SI G ++LP V SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDVVDTFRPTARINSICGRCSLLPEVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQHKQ+C LEDQLV+L++ ME+SE Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317 Query: 223 ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282 E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDHLMWVLL Sbjct: 318 EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377 Query: 283 QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342 QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+HL +KA+ Sbjct: 378 QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437 Query: 343 TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400 ++ + +P +L++ ++FLQ + ++ +DY+IALLCNAYSTN E PMG + Sbjct: 438 NDNSKLQIPIPHSLRLHHEFLQQSLRHKSLQM--NDYKIALLCNAYSTNSECVTLPMGAL 495 Query: 401 IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457 +ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V KLA K+ Sbjct: 496 VETIYGNGIMRLPLPGTNCMASASITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555 Query: 458 NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517 ++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR Sbjct: 556 SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611 Query: 518 IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577 +HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+ Sbjct: 612 MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671 Query: 578 PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632 PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH W+ HT Sbjct: 672 PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731 Query: 633 LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691 L CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC Sbjct: 732 LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791 Query: 692 LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751 LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + KC++ +N Sbjct: 792 LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851 Query: 752 DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811 D++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFVKENSPE Sbjct: 852 DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910 Query: 812 HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864 HW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR +PVFDIV Sbjct: 911 HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970 Query: 865 VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924 +HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE V A+ Sbjct: 971 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030 Query: 925 LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984 +G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077 Query: 985 TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ K ++ Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137 Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101 P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF+ Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197 Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AL121575-6|CAI23321.1| 1374|Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa protein. Length = 1374 Score = 1162 bits (2878), Expect = 0.0 Identities = 567/1057 (53%), Positives = 750/1057 (70%), Gaps = 50/1057 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQ HKQ+C LEDQLV+L++ Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317 Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276 ME+SE E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDH Sbjct: 318 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377 Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336 LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+H Sbjct: 378 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437 Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394 L +KA+ ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + Sbjct: 438 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495 Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451 PMG ++ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V K Sbjct: 496 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555 Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511 LA K+++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL Sbjct: 556 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611 Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571 +MFSYR+HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q Sbjct: 612 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671 Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626 +R +S+PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH Sbjct: 672 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731 Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686 W+ HTL CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ Sbjct: 732 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791 Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745 PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + K Sbjct: 792 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851 Query: 746 CVDAINDIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFV 805 C++ +ND++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFV Sbjct: 852 CIEILNDMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFV 910 Query: 806 KENSPEHWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLI 858 KENSPEHW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR + Sbjct: 911 KENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFL 970 Query: 859 PVFDIVVHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXX 918 PVFDIV+HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE Sbjct: 971 PVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKR 1030 Query: 919 XXVGAVLGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHK 978 V A++G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 KLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------ 1083 Query: 979 TTKQKYTMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVIT 1036 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ Sbjct: 1084 ------TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVL 1137 Query: 1037 KGFVVIPTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLF 1095 K ++P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF Sbjct: 1138 KSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLF 1197 Query: 1096 NLATTSDAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 DFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1234 Score = 58.4 bits (135), Expect = 1e-07 Identities = 22/39 (56%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +V+ +I L+PAL++RLRFITH++ Sbjct: 1304 LYHMKYMFTGDSVKEQVKKIICNLKPALKLRLRFITHIS 1342 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AL121575-4|CAI23319.1| 1365|Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa protein. Length = 1365 Score = 1162 bits (2878), Expect = 0.0 Identities = 567/1057 (53%), Positives = 750/1057 (70%), Gaps = 50/1057 (4%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQ HKQ+C LEDQLV+L++ Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317 Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276 ME+SE E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDH Sbjct: 318 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377 Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336 LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+H Sbjct: 378 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437 Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394 L +KA+ ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + Sbjct: 438 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495 Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451 PMG ++ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V K Sbjct: 496 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555 Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511 LA K+++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL Sbjct: 556 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611 Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571 +MFSYR+HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q Sbjct: 612 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671 Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626 +R +S+PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH Sbjct: 672 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731 Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686 W+ HTL CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ Sbjct: 732 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791 Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745 PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + K Sbjct: 792 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851 Query: 746 CVDAINDIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFV 805 C++ +ND++WKYNIVT+DRL+LCL +R + +GNE+QV +IIQLLLL + RNRV DFV Sbjct: 852 CIEILNDMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFV 910 Query: 806 KENSPEHWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLI 858 KENSPEHW QN+W+ KH+ + +KYPEK E + P+ P+Y NVCLR + Sbjct: 911 KENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFL 970 Query: 859 PVFDIVVHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXX 918 PVFDIV+HR LE+ V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE Sbjct: 971 PVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKR 1030 Query: 919 XXVGAVLGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHK 978 V A++G+LKD RP GW ++T N +N WVPD YY L+ R+VD Sbjct: 1031 KLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------ 1083 Query: 979 TTKQKYTMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVIT 1036 TM G S FPN DWRFNE+PNP+AHAL+VTCVELM+L V+ VGN+LL+V+ Sbjct: 1084 ------TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVL 1137 Query: 1037 KGFVVIPTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLF 1095 K ++P + W+NAIGLI+ ALP+PYW VLH+R++ + +S + E + PF+LF Sbjct: 1138 KSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLF 1197 Query: 1096 NLATTSDAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132 + + E S TLA AHA+W+H+ GQ+ +P Sbjct: 1198 DFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1234 Score = 60.1 bits (139), Expect = 5e-08 Identities = 23/39 (58%), Positives = 34/39 (87%) Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171 +YH+KYMF GD++K +VE +I L+PAL++RLRFITH++ Sbjct: 1304 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1342 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AL121575-8|CAB92073.1| 886|Homo sapiens cofactor required for Sp1 transcriptional activation, subunit 3, 130kDa protein. Length = 886 Score = 803 bits (1986), Expect = 0.0 Identities = 388/685 (56%), Positives = 513/685 (74%), Gaps = 26/685 (3%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQ HKQ+C LEDQLV+L++ Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317 Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276 ME+SE E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDH Sbjct: 318 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377 Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336 LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+H Sbjct: 378 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437 Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394 L +KA+ ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + Sbjct: 438 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495 Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451 PMG ++ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V K Sbjct: 496 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555 Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511 LA K+++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL Sbjct: 556 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611 Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571 +MFSYR+HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q Sbjct: 612 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671 Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626 +R +S+PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH Sbjct: 672 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731 Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686 W+ HTL CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ Sbjct: 732 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791 Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745 PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + K Sbjct: 792 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851 Query: 746 CVDAINDIIWKYNIVTIDRLVLCLV 770 C++ +ND++WKYNIVT+DRL+LCLV Sbjct: 852 CIEILNDMVWKYNIVTLDRLILCLV 876 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 95 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147 >AF104255-1|AAD12724.1| 936|Homo sapiens transcriptional co-activator CRSP130 protein. Length = 936 Score = 803 bits (1986), Expect = 0.0 Identities = 388/685 (56%), Positives = 513/685 (74%), Gaps = 26/685 (3%) Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162 L L++ FV++ +P A++ SI G ++LPVV SG + N W+LDP TL+F LKG LP Sbjct: 251 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 307 Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216 YD +L +PQ L+R+VL+QPYSRDM+C+MLGL KQ HKQ+C LEDQLV+L++ Sbjct: 308 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 367 Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276 ME+SE E D+ + W HLSSQ+I+ +L FASFP++V+ LH KL G + KGRDH Sbjct: 368 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 427 Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336 LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K TH A+ CIW+H Sbjct: 428 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 487 Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394 L +KA+ ++ + +P +L++ ++FLQ + + ++ +DY+IALLCNAYSTN E + Sbjct: 488 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 545 Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451 PMG ++ET++GN + PLP + A PL M +LDSLT+H KMSLIHSI T V K Sbjct: 546 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 605 Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511 LA K+++ ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL Sbjct: 606 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 661 Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571 +MFSYR+HH+QPHYRVQLLS++H+LAA Q NQ QL LC ESTALRLIT+LGSS VQ Q Sbjct: 662 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 721 Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626 +R +S+PK+++S+ESEELNR L+LTLAR H+ GSD G K++L TIM+ TPH Sbjct: 722 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 781 Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686 W+ HTL CFP L FF Q + +E++ LKK+VEEEYRKW SM+N+NDII+HFS+ G+ Sbjct: 782 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 841 Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745 PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E + AGG + K Sbjct: 842 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 901 Query: 746 CVDAINDIIWKYNIVTIDRLVLCLV 770 C++ +ND++WKYNIVT+DRL+LCLV Sbjct: 902 CIEILNDMVWKYNIVTLDRLILCLV 926 Score = 56.0 bits (129), Expect = 8e-07 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%) Query: 57 RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108 R++C+ ++ ++ L ++ W F L+R+IIGGVDYKGVR+++K L K+LT Sbjct: 145 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 197 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.323 0.137 0.420 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 178,819,429 Number of Sequences: 224733 Number of extensions: 7855094 Number of successful extensions: 16635 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 16504 Number of HSP's gapped (non-prelim): 28 length of query: 1178 length of database: 73,234,838 effective HSP length: 98 effective length of query: 1080 effective length of database: 51,211,004 effective search space: 55307884320 effective search space used: 55307884320 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (22.0 bits) S2: 71 (32.7 bits)
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