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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000550-TA|BGIBMGA000550-PA|undefined
         (1178 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC060759-1|AAH60759.1| 1359|Homo sapiens CRSP3 protein protein.      1170   0.0  
AL121575-7|CAB92072.1| 1368|Homo sapiens cofactor required for S...  1170   0.0  
AL121575-5|CAI23320.1| 1364|Homo sapiens cofactor required for S...  1170   0.0  
AB033042-1|BAA86530.1| 1421|Homo sapiens KIAA1216 protein protein.   1170   0.0  
AF105332-1|AAD31729.1| 1368|Homo sapiens vitamin D3 receptor int...  1170   0.0  
AF135022-1|AAD30202.1| 1364|Homo sapiens mediator protein.           1164   0.0  
AL121575-6|CAI23321.1| 1374|Homo sapiens cofactor required for S...  1162   0.0  
AL121575-4|CAI23319.1| 1365|Homo sapiens cofactor required for S...  1162   0.0  
AL121575-8|CAB92073.1|  886|Homo sapiens cofactor required for S...   803   0.0  
AF104255-1|AAD12724.1|  936|Homo sapiens transcriptional co-acti...   803   0.0  

>BC060759-1|AAH60759.1| 1359|Homo sapiens CRSP3 protein protein.
          Length = 1359

 Score = 1170 bits (2899), Expect = 0.0
 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 318  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 378  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E +  PMG +
Sbjct: 438  NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 496  VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 556  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 612  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 672  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 732  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 792  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 852  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +PVFDIV
Sbjct: 911  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 971  IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AL121575-7|CAB92072.1| 1368|Homo sapiens cofactor required for Sp1
            transcriptional activation, subunit 3, 130kDa protein.
          Length = 1368

 Score = 1170 bits (2899), Expect = 0.0
 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 318  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 378  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E +  PMG +
Sbjct: 438  NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 496  VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 556  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 612  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 672  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 732  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 792  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 852  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +PVFDIV
Sbjct: 911  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 971  IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AL121575-5|CAI23320.1| 1364|Homo sapiens cofactor required for Sp1
            transcriptional activation, subunit 3, 130kDa protein.
          Length = 1364

 Score = 1170 bits (2899), Expect = 0.0
 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 318  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 378  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E +  PMG +
Sbjct: 438  NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 496  VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 556  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 612  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 672  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 732  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 792  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 852  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +PVFDIV
Sbjct: 911  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 971  IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AB033042-1|BAA86530.1| 1421|Homo sapiens KIAA1216 protein protein.
          Length = 1421

 Score = 1170 bits (2899), Expect = 0.0
 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 254  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 310

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 311  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 370

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 371  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 430

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 431  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 490

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E +  PMG +
Sbjct: 491  NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 548

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 549  VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 608

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 609  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 664

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 665  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 724

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 725  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 784

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 785  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 844

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 845  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 904

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 905  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 963

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +PVFDIV
Sbjct: 964  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 1023

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 1024 IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1083

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1084 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1130

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1131 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1190

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1191 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1250

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1251 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1281



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1351 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1389



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 148 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 200


>AF105332-1|AAD31729.1| 1368|Homo sapiens vitamin D3 receptor
            interacting protein protein.
          Length = 1368

 Score = 1170 bits (2898), Expect = 0.0
 Identities = 567/1051 (53%), Positives = 750/1051 (71%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 318  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 378  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E +  PMG +
Sbjct: 438  NDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFTLPMGAL 495

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 496  VETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 556  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 612  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 672  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 732  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 792  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 852  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAP-------IPVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P       +P+Y  NVCLR +PVFDIV
Sbjct: 911  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPCTDPVSYLPIYFGNVCLRFLPVFDIV 970

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 971  IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336



 Score = 52.4 bits (120), Expect = 9e-06
 Identities = 22/53 (41%), Positives = 37/53 (69%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVD KGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDNKGVRDLLKVILEKILT 147


>AF135022-1|AAD30202.1| 1364|Homo sapiens mediator protein.
          Length = 1364

 Score = 1164 bits (2884), Expect = 0.0
 Identities = 565/1051 (53%), Positives = 746/1051 (70%), Gaps = 44/1051 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++  V++ +P A++ SI G  ++LP V  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDVVDTFRPTARINSICGRCSLLPEVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQHKQQCIALEDQLVELMILPMEKSEQ 222
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQHKQ+C  LEDQLV+L++  ME+SE 
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQHKQRCPVLEDQLVDLVVYAMERSET 317

Query: 223  ENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDHLMWVLL 282
            E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDHLMWVLL
Sbjct: 318  EEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLL 377

Query: 283  QFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMHLLKKAE 342
            QFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+HL +KA+
Sbjct: 378  QFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQ 437

Query: 343  TEHKTM--TMPPNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYARPMGII 400
             ++  +   +P +L++ ++FLQ  +   ++    +DY+IALLCNAYSTN E    PMG +
Sbjct: 438  NDNSKLQIPIPHSLRLHHEFLQQSLRHKSLQM--NDYKIALLCNAYSTNSECVTLPMGAL 495

Query: 401  IETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAKLAQNKT 457
            +ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V KLA  K+
Sbjct: 496  VETIYGNGIMRLPLPGTNCMASASITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKS 555

Query: 458  NIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLLDMFSYR 517
            ++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL+MFSYR
Sbjct: 556  SV----ALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYR 611

Query: 518  IHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQMSRVVSE 577
            +HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q +R +S+
Sbjct: 612  MHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSD 671

Query: 578  PKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPHMWSQHT 632
            PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH W+ HT
Sbjct: 672  PKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHT 731

Query: 633  LQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT-PLFLC 691
            L CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+ PLFLC
Sbjct: 732  LSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLC 791

Query: 692  LLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYKCVDAIN 751
            LLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + KC++ +N
Sbjct: 792  LLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILN 851

Query: 752  DIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFVKENSPE 811
            D++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFVKENSPE
Sbjct: 852  DMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPE 910

Query: 812  HWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLIPVFDIV 864
            HW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +PVFDIV
Sbjct: 911  HWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIV 970

Query: 865  VHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXXXXVGAV 924
            +HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE             V A+
Sbjct: 971  IHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAI 1030

Query: 925  LGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHKTTKQKY 984
            +G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD            
Sbjct: 1031 IGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------------ 1077

Query: 985  TMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVITKGFVVI 1042
            TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ K   ++
Sbjct: 1078 TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLV 1137

Query: 1043 PTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLFNLATTS 1101
            P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF+     
Sbjct: 1138 PRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACH 1197

Query: 1102 DAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
             +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 QSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1228



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1298 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1336



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AL121575-6|CAI23321.1| 1374|Homo sapiens cofactor required for Sp1
            transcriptional activation, subunit 3, 130kDa protein.
          Length = 1374

 Score = 1162 bits (2878), Expect = 0.0
 Identities = 567/1057 (53%), Positives = 750/1057 (70%), Gaps = 50/1057 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQ      HKQ+C  LEDQLV+L++  
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317

Query: 217  MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276
            ME+SE E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDH
Sbjct: 318  MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377

Query: 277  LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336
            LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+H
Sbjct: 378  LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437

Query: 337  LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394
            L +KA+ ++  + +P   +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E + 
Sbjct: 438  LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495

Query: 395  RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451
             PMG ++ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V K
Sbjct: 496  LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555

Query: 452  LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511
            LA  K+++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL
Sbjct: 556  LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611

Query: 512  DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571
            +MFSYR+HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q 
Sbjct: 612  EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671

Query: 572  SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626
            +R +S+PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH
Sbjct: 672  TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731

Query: 627  MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686
             W+ HTL CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+
Sbjct: 732  NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791

Query: 687  -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745
             PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + K
Sbjct: 792  PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851

Query: 746  CVDAINDIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFV 805
            C++ +ND++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFV
Sbjct: 852  CIEILNDMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFV 910

Query: 806  KENSPEHWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLI 858
            KENSPEHW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +
Sbjct: 911  KENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFL 970

Query: 859  PVFDIVVHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXX 918
            PVFDIV+HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE           
Sbjct: 971  PVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKR 1030

Query: 919  XXVGAVLGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHK 978
              V A++G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD      
Sbjct: 1031 KLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------ 1083

Query: 979  TTKQKYTMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVIT 1036
                  TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ 
Sbjct: 1084 ------TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVL 1137

Query: 1037 KGFVVIPTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLF 1095
            K   ++P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF
Sbjct: 1138 KSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLF 1197

Query: 1096 NLATTSDAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
            +      +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 DFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1234



 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 22/39 (56%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +V+ +I  L+PAL++RLRFITH++
Sbjct: 1304 LYHMKYMFTGDSVKEQVKKIICNLKPALKLRLRFITHIS 1342



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AL121575-4|CAI23319.1| 1365|Homo sapiens cofactor required for Sp1
            transcriptional activation, subunit 3, 130kDa protein.
          Length = 1365

 Score = 1162 bits (2878), Expect = 0.0
 Identities = 567/1057 (53%), Positives = 750/1057 (70%), Gaps = 50/1057 (4%)

Query: 103  LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
            L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201  LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163  YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216
            YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQ      HKQ+C  LEDQLV+L++  
Sbjct: 258  YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317

Query: 217  MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276
            ME+SE E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDH
Sbjct: 318  MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377

Query: 277  LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336
            LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+H
Sbjct: 378  LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437

Query: 337  LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394
            L +KA+ ++  + +P   +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E + 
Sbjct: 438  LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495

Query: 395  RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451
             PMG ++ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V K
Sbjct: 496  LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555

Query: 452  LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511
            LA  K+++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL
Sbjct: 556  LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611

Query: 512  DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571
            +MFSYR+HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q 
Sbjct: 612  EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671

Query: 572  SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626
            +R +S+PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH
Sbjct: 672  TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731

Query: 627  MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686
             W+ HTL CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+
Sbjct: 732  NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791

Query: 687  -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745
             PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + K
Sbjct: 792  PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851

Query: 746  CVDAINDIIWKYNIVTIDRLVLCLVLRPNPDGNESQVSLYIIQLLLLHGFELRNRVQDFV 805
            C++ +ND++WKYNIVT+DRL+LCL +R + +GNE+QV  +IIQLLLL   + RNRV DFV
Sbjct: 852  CIEILNDMVWKYNIVTLDRLILCLAMRSH-EGNEAQVCYFIIQLLLLKPNDFRNRVSDFV 910

Query: 806  KENSPEHWKQNNWYEKHLAFQRKYPEKFTPEEASGAYGAPI-------PVYLSNVCLRLI 858
            KENSPEHW QN+W+ KH+ + +KYPEK   E  +     P+       P+Y  NVCLR +
Sbjct: 911  KENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFL 970

Query: 859  PVFDIVVHRHLEIHQVAKYLEQLLEHLGYLYKFHDRPITFLYNTLHYYEXXXXXXXXXXX 918
            PVFDIV+HR LE+  V+K LE LL+HLG LYKFHDRP+T+LYNTLHYYE           
Sbjct: 971  PVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKR 1030

Query: 919  XXVGAVLGALKDVRPAGWAATETLQNFLANTEYDNTTWVPDLNYYLSLVNRMVDSILFHK 978
              V A++G+LKD RP GW  ++T      N   +N  WVPD  YY  L+ R+VD      
Sbjct: 1031 KLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREEN-PWVPDDTYYCRLIGRLVD------ 1083

Query: 979  TTKQKYTMMGNS--HFPNTDWRFNEYPNPSAHALYVTCVELMSLPVAPNYVGNSLLDVIT 1036
                  TM G S   FPN DWRFNE+PNP+AHAL+VTCVELM+L V+   VGN+LL+V+ 
Sbjct: 1084 ------TMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVL 1137

Query: 1037 KGFVVIPTTKLQLWINAIGLIMAALPDPYWTVLHERLLELTTSSEMI-EWTYPYSPFQLF 1095
            K   ++P   +  W+NAIGLI+ ALP+PYW VLH+R++ + +S  +  E  +   PF+LF
Sbjct: 1138 KSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLF 1197

Query: 1096 NLATTSDAMLENKYSLTLACAHAIWYHAGAGQIMQVP 1132
            +      +  E   S TLA AHA+W+H+  GQ+  +P
Sbjct: 1198 DFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIP 1234



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 23/39 (58%), Positives = 34/39 (87%)

Query: 1133 IYHIKYMFVGDTLKNEVENVIRKLRPALQMRLRFITHLN 1171
            +YH+KYMF GD++K +VE +I  L+PAL++RLRFITH++
Sbjct: 1304 LYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHIS 1342



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AL121575-8|CAB92073.1|  886|Homo sapiens cofactor required for Sp1
           transcriptional activation, subunit 3, 130kDa protein.
          Length = 886

 Score =  803 bits (1986), Expect = 0.0
 Identities = 388/685 (56%), Positives = 513/685 (74%), Gaps = 26/685 (3%)

Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
           L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 201 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 257

Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216
           YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQ      HKQ+C  LEDQLV+L++  
Sbjct: 258 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 317

Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276
           ME+SE E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDH
Sbjct: 318 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 377

Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336
           LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+H
Sbjct: 378 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 437

Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394
           L +KA+ ++  + +P   +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E + 
Sbjct: 438 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 495

Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451
            PMG ++ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V K
Sbjct: 496 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 555

Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511
           LA  K+++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL
Sbjct: 556 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 611

Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571
           +MFSYR+HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q 
Sbjct: 612 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 671

Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626
           +R +S+PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH
Sbjct: 672 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 731

Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686
            W+ HTL CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+
Sbjct: 732 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 791

Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745
            PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + K
Sbjct: 792 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 851

Query: 746 CVDAINDIIWKYNIVTIDRLVLCLV 770
           C++ +ND++WKYNIVT+DRL+LCLV
Sbjct: 852 CIEILNDMVWKYNIVTLDRLILCLV 876



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 95  RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 147


>AF104255-1|AAD12724.1|  936|Homo sapiens transcriptional
           co-activator CRSP130 protein.
          Length = 936

 Score =  803 bits (1986), Expect = 0.0
 Identities = 388/685 (56%), Positives = 513/685 (74%), Gaps = 26/685 (3%)

Query: 103 LAKLLTSFVESTKPCAQMVSIIGHSNMLPVVEFSGFADHLVNPWRLDPTTLKFSLKGNLP 162
           L  L++ FV++ +P A++ SI G  ++LPVV  SG    + N W+LDP TL+F LKG LP
Sbjct: 251 LGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGA---ICNSWKLDPATLRFPLKGLLP 307

Query: 163 YDDELLKPQIGLIRHVLQQPYSRDMMCSMLGLQKQ------HKQQCIALEDQLVELMILP 216
           YD +L +PQ  L+R+VL+QPYSRDM+C+MLGL KQ      HKQ+C  LEDQLV+L++  
Sbjct: 308 YDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYA 367

Query: 217 MEKSEQENDEDEMSPTHWCWLHLSSQVIYLILIGFASFPNIVMGLHNKLVGHDMKKGRDH 276
           ME+SE E   D+   +   W HLSSQ+I+ +L  FASFP++V+ LH KL G  + KGRDH
Sbjct: 368 MERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDH 427

Query: 277 LMWVLLQFISGSIQRHPLSNFIPIIKLHELLYPEKDPLPVPDYSKAHCTHQMAVVCIWMH 336
           LMWVLLQFISGSIQ++ L++F+P++KL +LLYPEK+ +PVPD +K   TH  A+ CIW+H
Sbjct: 428 LMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIH 487

Query: 337 LLKKAETEHKTMTMP--PNLKVQYDFLQHLMTSNNIPTLGSDYRIALLCNAYSTNQEYYA 394
           L +KA+ ++  + +P   +L++ ++FLQ  + + ++    +DY+IALLCNAYSTN E + 
Sbjct: 488 LNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQM--NDYKIALLCNAYSTNSECFT 545

Query: 395 RPMGIIIETLFGN---QKPLPNGSTTAPLPTVPLSMCILDSLTLHCKMSLIHSIVTHVAK 451
            PMG ++ET++GN   + PLP  +  A     PL M +LDSLT+H KMSLIHSI T V K
Sbjct: 546 LPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIK 605

Query: 452 LAQNKTNIPGNNMMSPALVETYSRLLVYTEIESLGIKGFINQLLPNVFKSHAWGILHDLL 511
           LA  K+++     ++PALVETYSRLLVY EIESLGIKGFI+QLLP VFKSHAWGILH LL
Sbjct: 606 LAHAKSSVA----LAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLL 661

Query: 512 DMFSYRIHHVQPHYRVQLLSNIHSLAAYPQANQTQLQLCFESTALRLITSLGSSGVQLQM 571
           +MFSYR+HH+QPHYRVQLLS++H+LAA  Q NQ QL LC ESTALRLIT+LGSS VQ Q 
Sbjct: 662 EMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQF 721

Query: 572 SRVVSEPKSLVSSESEELNRVLVLTLARGIHMAG--AGSD---GAAVKELLTTIMTNTPH 626
           +R +S+PK+++S+ESEELNR L+LTLAR  H+     GSD   G   K++L TIM+ TPH
Sbjct: 722 TRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPH 781

Query: 627 MWSQHTLQCFPPVLVEFFNQISAQKENKQLLKKSVEEEYRKWTSMANDNDIISHFSVPGT 686
            W+ HTL CFP  L  FF Q +  +E++  LKK+VEEEYRKW SM+N+NDII+HFS+ G+
Sbjct: 782 NWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGS 841

Query: 687 -PLFLCLLWKMIFETNRINPIAFKILERIGARALSAHLRKFCDYLVFEVTDPAGGPHIYK 745
            PLFLCLLWKM+ ET+ IN I +++LERIGARAL AH+R F D+LV+E +  AGG  + K
Sbjct: 842 PPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNK 901

Query: 746 CVDAINDIIWKYNIVTIDRLVLCLV 770
           C++ +ND++WKYNIVT+DRL+LCLV
Sbjct: 902 CIEILNDMVWKYNIVTLDRLILCLV 926



 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 23/53 (43%), Positives = 38/53 (71%), Gaps = 1/53 (1%)

Query: 57  RMLCDCILTNEKLIYQNADFWIECFSLIRRIIGGVDYKGVREIMKQ-LAKLLT 108
           R++C+ ++ ++ L ++    W   F L+R+IIGGVDYKGVR+++K  L K+LT
Sbjct: 145 RLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILT 197


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.323    0.137    0.420 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 178,819,429
Number of Sequences: 224733
Number of extensions: 7855094
Number of successful extensions: 16635
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 16504
Number of HSP's gapped (non-prelim): 28
length of query: 1178
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1080
effective length of database: 51,211,004
effective search space: 55307884320
effective search space used: 55307884320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 71 (32.7 bits)

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