Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000544-TA|BGIBMGA000544-PA|IPR001611|Leucine-rich
repeat, IPR003591|Leucine-rich repeat, typical subtype
(562 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 93 2e-18
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 92 5e-18
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 92 5e-18
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 92 5e-18
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 92 5e-18
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 92 5e-18
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 91 7e-18
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 91 1e-17
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 91 1e-17
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 91 1e-17
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 91 1e-17
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 91 1e-17
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 89 5e-17
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 89 5e-17
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 89 5e-17
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 89 5e-17
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 88 7e-17
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 88 7e-17
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 88 7e-17
M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein... 87 2e-16
CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein. 87 2e-16
CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein. 87 2e-16
BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein. 87 2e-16
BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein. 87 2e-16
AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein. 87 2e-16
AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein. 87 2e-16
AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like fa... 86 3e-16
AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like fa... 86 3e-16
AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled recep... 86 3e-16
AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein. 86 3e-16
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 85 5e-16
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 85 5e-16
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 85 6e-16
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 84 1e-15
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 84 1e-15
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 84 1e-15
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 83 3e-15
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 83 3e-15
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 83 3e-15
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 83 3e-15
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 83 3e-15
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 83 3e-15
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 82 4e-15
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 82 6e-15
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 82 6e-15
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 82 6e-15
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 82 6e-15
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 82 6e-15
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 82 6e-15
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 81 8e-15
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 81 8e-15
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 81 8e-15
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 81 8e-15
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 81 8e-15
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 81 8e-15
L01131-1|AAA52301.1| 347|Homo sapiens decorin protein. 81 1e-14
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 81 1e-14
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 81 1e-14
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 81 1e-14
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 81 1e-14
AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled recep... 79 3e-14
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 79 5e-14
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 79 5e-14
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 79 5e-14
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 78 7e-14
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 78 9e-14
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 77 1e-13
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 77 1e-13
AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein. 77 1e-13
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 77 1e-13
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 77 1e-13
AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich r... 77 1e-13
AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein. 77 1e-13
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 77 2e-13
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 77 2e-13
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 77 2e-13
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 77 2e-13
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 77 2e-13
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 77 2e-13
BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein. 77 2e-13
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 77 2e-13
AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein. 77 2e-13
AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat tra... 77 2e-13
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 77 2e-13
AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens ... 77 2e-13
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 75 5e-13
BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat neu... 75 5e-13
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 75 7e-13
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 75 7e-13
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 75 7e-13
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 75 7e-13
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 75 7e-13
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 75 7e-13
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 75 7e-13
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 75 7e-13
X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein. 73 2e-12
BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein. 73 2e-12
AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein. 73 2e-12
AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament as... 73 2e-12
AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1) p... 73 2e-12
AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein. 73 2e-12
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 73 4e-12
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 72 5e-12
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 72 5e-12
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 72 5e-12
BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein. 72 5e-12
AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein. 72 5e-12
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 72 5e-12
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 72 5e-12
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 72 5e-12
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 72 5e-12
BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3 pr... 72 6e-12
U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3 prot... 71 8e-12
DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3 is... 71 8e-12
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 71 8e-12
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 71 8e-12
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 71 8e-12
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 71 8e-12
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 71 8e-12
BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3 pr... 71 8e-12
BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3 pr... 71 8e-12
BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3 pr... 71 8e-12
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 71 8e-12
BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein. 71 8e-12
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 71 8e-12
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 71 8e-12
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 71 8e-12
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 71 8e-12
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 71 8e-12
BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine ric... 71 1e-11
BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine ric... 71 1e-11
AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein. 71 1e-11
AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat tra... 71 1e-11
AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein. 71 1e-11
X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein. 70 2e-11
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 70 2e-11
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 70 2e-11
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 70 2e-11
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 70 2e-11
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 70 2e-11
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 70 2e-11
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 70 2e-11
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 70 2e-11
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 70 2e-11
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 70 2e-11
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 70 3e-11
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 70 3e-11
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 70 3e-11
BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat con... 70 3e-11
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 70 3e-11
AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein. 70 3e-11
AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens ... 70 3e-11
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 70 3e-11
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 70 3e-11
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 69 3e-11
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 69 3e-11
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 69 3e-11
AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein. 69 3e-11
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 69 3e-11
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 69 4e-11
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 69 4e-11
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 69 4e-11
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 69 6e-11
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 69 6e-11
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 69 6e-11
CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein. 69 6e-11
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 69 6e-11
BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat neu... 69 6e-11
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 69 6e-11
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 69 6e-11
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 69 6e-11
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 69 6e-11
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 69 6e-11
AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein. 69 6e-11
AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein. 69 6e-11
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 69 6e-11
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 69 6e-11
AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat neu... 69 6e-11
AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat pro... 69 6e-11
AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich r... 69 6e-11
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 68 8e-11
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 68 1e-10
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 68 1e-10
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 68 1e-10
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 68 1e-10
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 67 1e-10
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 67 1e-10
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 67 1e-10
AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein. 67 2e-10
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 66 2e-10
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 66 2e-10
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 66 2e-10
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 66 4e-10
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 65 5e-10
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 65 5e-10
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 65 5e-10
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 65 5e-10
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 65 5e-10
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 65 7e-10
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 64 9e-10
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 64 9e-10
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 64 9e-10
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 64 9e-10
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 64 9e-10
Z50749-1|CAA90626.1| 360|Homo sapiens yeast sds22 homolog protein. 64 2e-09
BT020134-1|AAV38936.1| 360|Homo sapiens protein phosphatase 1, ... 64 2e-09
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 64 2e-09
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 64 2e-09
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 64 2e-09
BC000910-1|AAH00910.1| 360|Homo sapiens protein phosphatase 1, ... 64 2e-09
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 64 2e-09
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AF067136-2|AAD26610.1| 317|Homo sapiens protein phosphatase-1 r... 64 2e-09
AF067136-1|AAD26611.1| 360|Homo sapiens protein phosphatase-1 r... 64 2e-09
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 63 2e-09
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 63 2e-09
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 63 2e-09
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 63 2e-09
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 63 2e-09
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 63 2e-09
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 63 2e-09
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 63 2e-09
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 63 2e-09
AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein. 63 3e-09
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 62 4e-09
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 62 4e-09
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 62 4e-09
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 62 4e-09
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 62 5e-09
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 62 5e-09
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 62 7e-09
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 62 7e-09
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 62 7e-09
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 62 7e-09
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 61 9e-09
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 61 9e-09
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 61 9e-09
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 61 9e-09
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 61 9e-09
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 61 9e-09
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 60 2e-08
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 60 2e-08
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 60 2e-08
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 60 2e-08
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 60 2e-08
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 60 2e-08
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 60 2e-08
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 60 3e-08
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 60 3e-08
BC046356-1|AAH46356.1| 421|Homo sapiens osteomodulin protein. 59 4e-08
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 59 4e-08
AY358872-1|AAQ89231.1| 421|Homo sapiens OMD protein. 59 4e-08
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 59 4e-08
AL137848-4|CAI16696.1| 421|Homo sapiens osteomodulin protein. 59 4e-08
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AB009589-1|BAA23982.1| 421|Homo sapiens Osteomodulin protein. 59 4e-08
AB000114-1|BAA19055.1| 421|Homo sapiens osteomodulin protein. 59 4e-08
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 59 5e-08
BC043165-1|AAH43165.1| 719|Homo sapiens leucine rich repeat and... 59 5e-08
BC032713-1|AAH32713.1| 1032|Homo sapiens toll-like receptor 9 pr... 59 5e-08
AY359085-1|AAQ89443.1| 1032|Homo sapiens TLR9 protein. 59 5e-08
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 59 5e-08
AK055365-1|BAB70910.1| 719|Homo sapiens protein ( Homo sapiens ... 59 5e-08
AF259263-1|AAF72190.1| 975|Homo sapiens toll-like receptor 9 fo... 59 5e-08
AF259262-1|AAF72189.1| 1032|Homo sapiens toll-like receptor 9 fo... 59 5e-08
AB045180-1|BAB19259.1| 1032|Homo sapiens toll-like receptor 9 pr... 59 5e-08
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 59 5e-08
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 58 6e-08
AF245704-1|AAF78037.1| 1032|Homo sapiens toll-like receptor 9 pr... 58 6e-08
BC020870-1|AAH20870.1| 649|Homo sapiens fibronectin leucine ric... 58 8e-08
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 58 8e-08
AY358319-1|AAQ88685.1| 649|Homo sapiens FLRT3 protein. 58 8e-08
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 58 8e-08
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 58 8e-08
AL132826-1|CAB86687.1| 649|Homo sapiens fibronectin leucine ric... 58 8e-08
AK074909-1|BAC11284.1| 649|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AK074883-1|BAC11265.1| 627|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AK027694-1|BAB55303.1| 623|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AK027297-1|BAB55023.1| 649|Homo sapiens protein ( Homo sapiens ... 58 8e-08
AF169677-1|AAF28461.1| 649|Homo sapiens leucine-rich repeat tra... 58 8e-08
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 58 8e-08
AB040902-1|BAA95993.1| 662|Homo sapiens KIAA1469 protein protein. 58 8e-08
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 58 8e-08
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 58 8e-08
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 58 1e-07
BC073974-1|AAH73974.1| 359|Homo sapiens chondroadherin protein. 57 1e-07
BC036360-1|AAH36360.1| 359|Homo sapiens chondroadherin protein. 57 1e-07
BC030958-1|AAH30958.1| 322|Homo sapiens epiphycan protein. 57 1e-07
AF371328-1|AAK51556.1| 359|Homo sapiens chondroadherin protein. 57 1e-07
AF138301-1|AAF61437.1| 250|Homo sapiens decorin B protein. 57 1e-07
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 57 2e-07
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 57 2e-07
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 57 2e-07
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 57 2e-07
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 57 2e-07
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 57 2e-07
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 57 2e-07
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 57 2e-07
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 57 2e-07
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 57 2e-07
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 57 2e-07
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 57 2e-07
U96769-1|AAC13410.1| 359|Homo sapiens chondroadherin protein. 56 3e-07
BT007296-1|AAP35960.1| 280|Homo sapiens protein phosphatase 1, ... 56 3e-07
BC013001-1|AAH13001.1| 280|Homo sapiens PPP1R7 protein protein. 56 3e-07
BC012397-1|AAH12397.1| 280|Homo sapiens PPP1R7 protein protein. 56 3e-07
AK092954-1|BAC04007.1| 325|Homo sapiens protein ( Homo sapiens ... 56 3e-07
AF067134-2|AAD26613.1| 237|Homo sapiens protein phosphatase-1 r... 56 3e-07
AF067134-1|AAD26612.1| 280|Homo sapiens protein phosphatase-1 r... 56 3e-07
BC041085-1|AAH41085.1| 865|Homo sapiens leucine-rich repeats an... 56 3e-07
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 56 3e-07
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 56 3e-07
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 56 3e-07
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 56 3e-07
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 56 3e-07
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 56 3e-07
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 56 3e-07
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 56 4e-07
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 55 6e-07
BC068558-1|AAH68558.1| 614|Homo sapiens LINGO1 protein protein. 55 6e-07
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 55 6e-07
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 55 6e-07
U59111-1|AAC50945.1| 322|Homo sapiens dermatan sulfate proteogl... 55 8e-07
AK001991-1|BAA92025.1| 273|Homo sapiens protein ( Homo sapiens ... 55 8e-07
BC111745-1|AAI11746.1| 653|Homo sapiens leucine rich repeat con... 54 1e-06
BC111561-1|AAI11562.1| 653|Homo sapiens leucine rich repeat con... 54 1e-06
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 54 1e-06
BC011057-1|AAH11057.2| 620|Homo sapiens leucine rich repeat and... 54 1e-06
AY358307-1|AAQ88674.1| 653|Homo sapiens NAG14 protein. 54 1e-06
AY324320-1|AAQ97216.1| 620|Homo sapiens leucine-rich repeat neu... 54 1e-06
AL834260-1|CAD38935.1| 577|Homo sapiens hypothetical protein pr... 54 1e-06
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 54 1e-06
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 54 1e-06
AF196976-1|AAG28019.2| 653|Homo sapiens brain tumor associated ... 54 1e-06
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 54 1e-06
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 54 1e-06
BC056900-1|AAH56900.1| 1504|Homo sapiens nischarin protein. 54 1e-06
BC054494-1|AAH54494.1| 1504|Homo sapiens nischarin protein. 54 1e-06
BC038102-1|AAH38102.1| 1504|Homo sapiens nischarin protein. 54 1e-06
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 54 1e-06
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 54 1e-06
AF082516-1|AAC33104.1| 1504|Homo sapiens I-1 receptor candidate ... 54 1e-06
AB023192-1|BAA76819.1| 1528|Homo sapiens KIAA0975 protein protein. 54 1e-06
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 54 2e-06
AK000136-1|BAA90967.1| 187|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 54 2e-06
BC111013-1|AAI11014.1| 428|Homo sapiens immunoglobulin superfam... 53 2e-06
BC074943-1|AAH74943.1| 332|Homo sapiens opticin protein. 53 2e-06
BC074942-1|AAH74942.1| 332|Homo sapiens opticin protein. 53 2e-06
BC048421-1|AAH48421.1| 453|Homo sapiens LOC150356 protein protein. 53 2e-06
BC022478-1|AAH22478.1| 428|Homo sapiens immunoglobulin superfam... 53 2e-06
AY358871-1|AAQ89230.1| 428|Homo sapiens ISLR protein. 53 2e-06
AY324323-1|AAQ97218.1| 479|Homo sapiens leucine-rich repeat neu... 53 2e-06
AY077681-1|AAL78286.1| 332|Homo sapiens opticin protein. 53 2e-06
AL391817-3|CAI17035.1| 332|Homo sapiens opticin protein. 53 2e-06
AK223267-1|BAD96987.1| 428|Homo sapiens immunoglobulin superfam... 53 2e-06
AJ133790-1|CAB53459.1| 332|Homo sapiens opticin protein. 53 2e-06
AF161702-1|AAD45900.1| 332|Homo sapiens oculoglycan protein. 53 2e-06
AB024537-1|BAA85971.1| 428|Homo sapiens ISLR protein. 53 2e-06
AB024536-1|BAA85970.1| 428|Homo sapiens ISLR protein. 53 2e-06
AB003184-1|BAA22848.1| 428|Homo sapiens ISLR protein. 53 2e-06
BC117276-1|AAI17277.1| 420|Homo sapiens reticulon 4 receptor-li... 53 3e-06
BC113673-1|AAI13674.1| 420|Homo sapiens reticulon 4 receptor-li... 53 3e-06
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 53 3e-06
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 53 3e-06
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 53 3e-06
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 53 3e-06
AY250221-1|AAP82838.1| 420|Homo sapiens nogo receptor-like 3 pr... 53 3e-06
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 53 3e-06
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 53 3e-06
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 53 3e-06
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 53 3e-06
AL442123-4|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 53 3e-06
AL442123-3|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 53 3e-06
AK172834-1|BAD18799.1| 459|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AJ297858-1|CAC82651.1| 649|Homo sapiens hypothetical protein pr... 53 3e-06
AF532858-1|AAP21835.1| 420|Homo sapiens Nogo-66 receptor homolo... 53 3e-06
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 53 3e-06
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 53 3e-06
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 52 4e-06
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 52 4e-06
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 52 4e-06
AK172751-1|BAD18737.1| 653|Homo sapiens protein ( Homo sapiens ... 52 4e-06
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 52 4e-06
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 52 4e-06
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 52 5e-06
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 52 5e-06
BC029858-1|AAH29858.1| 343|Homo sapiens leucine rich repeat con... 52 5e-06
AY358284-1|AAQ88651.1| 620|Homo sapiens QVSK201 protein. 52 5e-06
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 52 5e-06
AL512424-2|CAI14256.1| 380|Homo sapiens slit homolog 1 (Drosoph... 52 5e-06
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 52 5e-06
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 52 5e-06
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 52 7e-06
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 52 7e-06
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 52 7e-06
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 52 7e-06
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 52 7e-06
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 52 7e-06
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 52 7e-06
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 52 7e-06
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 51 9e-06
BC111067-1|AAI11068.1| 513|Homo sapiens leucine rich repeat con... 51 9e-06
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 51 9e-06
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 51 9e-06
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 51 9e-06
BC032460-1|AAH32460.1| 634|Homo sapiens Unknown (protein for IM... 51 9e-06
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 51 9e-06
AK223535-1|BAD97255.1| 343|Homo sapiens leucine-rich B7 protein... 51 9e-06
AB178281-1|BAD97811.1| 513|Homo sapiens LRRC24 protein protein. 51 9e-06
AL122074-1|CAB59249.1| 333|Homo sapiens hypothetical protein pr... 51 1e-05
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 51 1e-05
AF138302-1|AAD44714.1| 212|Homo sapiens decorin variant C protein. 51 1e-05
U88878-1|AAC34133.1| 784|Homo sapiens Toll-like receptor 2 prot... 50 2e-05
BC033756-1|AAH33756.1| 784|Homo sapiens TLR2 protein protein. 50 2e-05
AK128037-1|BAC87242.1| 1111|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AF051152-1|AAC34377.1| 784|Homo sapiens Toll/interleukin-1 rece... 50 2e-05
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 50 2e-05
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 50 2e-05
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 50 2e-05
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 50 2e-05
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 50 2e-05
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 50 2e-05
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 50 2e-05
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 50 2e-05
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 50 2e-05
Z29083-1|CAA82324.1| 420|Homo sapiens 5T4 oncofoetal antigen pr... 50 3e-05
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 50 3e-05
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
BC037161-1|AAH37161.1| 420|Homo sapiens trophoblast glycoprotei... 50 3e-05
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 50 3e-05
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 50 3e-05
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 50 3e-05
AL121977-2|CAI21546.1| 420|Homo sapiens trophoblast glycoprotei... 50 3e-05
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 50 3e-05
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 50 3e-05
AJ012159-1|CAA09930.1| 420|Homo sapiens 5T4 oncofetal trophobla... 50 3e-05
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 50 3e-05
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 50 3e-05
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 50 3e-05
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 49 4e-05
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 49 4e-05
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 49 4e-05
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 49 4e-05
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 49 4e-05
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 49 4e-05
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 49 4e-05
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 49 4e-05
BC071866-1|AAH71866.1| 460|Homo sapiens Unknown (protein for IM... 49 4e-05
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 49 4e-05
BC015581-1|AAH15581.2| 635|Homo sapiens leucine rich repeat and... 49 4e-05
BC007718-1|AAH07718.1| 541|Homo sapiens LRFN4 protein protein. 49 4e-05
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 49 4e-05
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 49 4e-05
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 49 4e-05
AL591063-1|CAI15264.1| 789|Homo sapiens RP11-535K1.2 protein. 49 4e-05
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 49 4e-05
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 49 4e-05
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 49 4e-05
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 49 4e-05
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 49 4e-05
AB209005-1|BAD92242.1| 622|Homo sapiens leucine rich repeat and... 49 4e-05
AB033072-1|BAA86560.1| 832|Homo sapiens KIAA1246 protein protein. 49 4e-05
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 49 4e-05
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 49 5e-05
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 49 5e-05
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 49 5e-05
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 49 5e-05
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 49 5e-05
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 49 5e-05
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 48 7e-05
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 48 7e-05
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 48 7e-05
Z94160-2|CAI22122.1| 820|Homo sapiens protein ( Human DNA seque... 48 9e-05
CR456360-1|CAG30246.1| 473|Homo sapiens Em:AC007663.1 protein. 48 9e-05
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 48 9e-05
BC011787-1|AAH11787.1| 473|Homo sapiens reticulon 4 receptor pr... 48 9e-05
AY358297-1|AAQ88664.1| 473|Homo sapiens NOGOR protein. 48 9e-05
AJ314647-1|CAC44536.1| 946|Homo sapiens hypothetical protein pr... 48 9e-05
AF502291-1|AAM23001.1| 586|Homo sapiens toll-like receptor 2 pr... 48 9e-05
AF283463-1|AAG53612.1| 473|Homo sapiens Nogo receptor protein. 48 9e-05
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 48 9e-05
AB067491-1|BAB67797.1| 821|Homo sapiens KIAA1904 protein protein. 48 9e-05
>AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich
repeat-containing G protein-coupled receptor 4 precursor
variant protein.
Length = 1032
Score = 93.1 bits (221), Expect = 2e-18
Identities = 96/352 (27%), Positives = 154/352 (43%), Gaps = 13/352 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNT 98
+ LD+ N IT+L E+ F++ LE L +A N +S I AL K LK + L N+L T
Sbjct: 141 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 200
Query: 99 L-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ + A+R L L+ + ++AN++ S+ + +++ + N L +P L +P+L
Sbjct: 201 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 260
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
Q+L N I S+ D +L+ + L NKI L++ F + L LD+ YN L
Sbjct: 261 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE 320
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS-LENLVDVE 274
++++L SL+ L N ++ G L I L N +S + S NL D+
Sbjct: 321 FPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLH 380
Query: 275 TRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHI 334
+ V+ + I I +SYN+I
Sbjct: 381 SLVIR----GASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNI 436
Query: 335 TTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
L S +LEE+ N I + + F GL SL DLS N IH ++
Sbjct: 437 RDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIH 486
Score = 81.8 bits (193), Expect = 6e-15
Identities = 60/245 (24%), Positives = 113/245 (46%), Gaps = 4/245 (1%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L +N L +P ++ L +++L L N IT + E+ F + +L HL + DN ++E+
Sbjct: 192 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 251
Query: 80 DALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
L L+ + L +NK++++ + A +L L + ++ N ++S+ ++ +
Sbjct: 252 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETL 311
Query: 137 HAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD 195
+N L P +K +PSL+ L F+ N+I + + L+R I L N + F+
Sbjct: 312 DLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNS 371
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L L I + +L L L LT ++ + + L +DL
Sbjct: 372 AFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDL 431
Query: 256 SHNQI 260
S+N I
Sbjct: 432 SYNNI 436
Score = 79.4 bits (187), Expect = 3e-14
Identities = 66/257 (25%), Positives = 118/257 (45%), Gaps = 4/257 (1%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F L + + L DNSL E+P H L +LP ++ L L NKI+ + + F ++ L
Sbjct: 227 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 286
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + +N+I + + L+ + L N L A++ L L+ + ++N++ I +
Sbjct: 287 LHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPD 346
Query: 125 ELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
++ IH N L + S + L SL G ++ L + +L +
Sbjct: 347 GAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLT 406
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
L+ KI + + E + L LD++YN ++ L S +L ++L N + +
Sbjct: 407 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALEEISLQRNQIYQIKEGT 465
Query: 244 IKGLRRLSVIDLSHNQI 260
+GL L ++DLS N I
Sbjct: 466 FQGLISLRILDLSRNLI 482
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 8/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N + L +H L +++TLDL N + + + + + L
Sbjct: 273 IPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQA-IKALPSL 331
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L N IS I A L+ +HL N L+ + N A +L DL + I ++
Sbjct: 332 KELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQ 391
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
L T ++ + ++ S+P++L + L++L NNI+ L + L
Sbjct: 392 QFPNL-TGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALE 449
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEF 239
I L N+I + + F L LD++ N + ++ + +L + L+++ N +T F
Sbjct: 450 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSF 509
Query: 240 SLQEIKGLRRLSVI 253
+ + GL +L ++
Sbjct: 510 PTEGLNGLNQLKLV 523
Score = 56.8 bits (131), Expect = 2e-07
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 18/287 (6%)
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFS 240
+ +S N I L +D F L EL +A N+L +++ +L LK L+ L L +N +
Sbjct: 143 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 202
Query: 241 LQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX- 298
+ I+GL L + L N I S+ S E LV + L LD N +
Sbjct: 203 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLR----HLWLDDNSLTEVPVHPLSNLP 258
Query: 299 XXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI 358
I I + N I +L + L +LE L ++NN+
Sbjct: 259 TLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNL 318
Query: 359 TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV-LCDDH 417
+ LPSL +L F H+ + ++ +G P + I+L DNP+ +
Sbjct: 319 GEFPQAIKALPSL--KELGF---HSNSISVIPDG--AFDGNPLLRTIHLYDNPLSFVGNS 371
Query: 418 LYELVTVFESLNARVSGASTCVA-PQTTAPILMRALNDIGPKKENSP 463
+ ++ SL R GAS P T + + +L G K + P
Sbjct: 372 AFHNLSDLHSLVIR--GASMVQQFPNLTGTVHLESLTLTGTKISSIP 416
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 91.9 bits (218), Expect = 5e-18
Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 9/283 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 58 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + ++ N ++ +
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLS 185
++ + +N+LQ P ++ + LQ L F+ NNIK++ E L++ I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I+F+ + F KL L + L+ SL L LT + +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 297
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L RL V++LSHNQI L SL +E E+ L HN I+
Sbjct: 298 QLPRLRVLELSHNQIEELP-SLHRCQKLE----EIGLQHNRIW 335
Score = 81.8 bits (193), Expect = 6e-15
Identities = 67/261 (25%), Positives = 125/261 (47%), Gaps = 6/261 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F+++
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L L + +N+I + + L+ + L NKL A+R L L+ + + NN+K+
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 122 IENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNL 179
I + +Q IH N +Q + S + +P L +L G +I+ + L+ + +L
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSL 278
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ L+ I L + +L L++++N+++ L SL + L + L HN + E
Sbjct: 279 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEI 337
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L L +DLS N I
Sbjct: 338 GADTFSQLSSLQALDLSWNAI 358
Score = 67.3 bits (157), Expect = 1e-10
Identities = 63/254 (24%), Positives = 121/254 (47%), Gaps = 10/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L H + L +++TLDL NK+ + R + L
Sbjct: 149 IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRL 207
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLK 120
+ L +N I I + A L+ +H N + + A + L L + +N A +++
Sbjct: 208 QELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQ 267
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
+ T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L
Sbjct: 268 EFPDLKGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKL 324
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
IGL N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T
Sbjct: 325 EEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTT 384
Query: 239 FSLQEIKGLRRLSV 252
L + GL L +
Sbjct: 385 LPLAGLGGLMHLKL 398
Score = 61.3 bits (142), Expect = 9e-09
Identities = 90/396 (22%), Positives = 162/396 (40%), Gaps = 42/396 (10%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 81 ALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
AL + L+ + L N ++ + + L L ++++ N L E+P +A
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL----TEIPVRA------- 129
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDD 196
L +P+LQ++ N I + D Q +L+ + L N+I+ L
Sbjct: 130 ------------LNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
F L LD+ YN+L+ ++R+L L+ L +N + + G L I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 257 HNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXX 315
N I + + + L + T L +D I+ +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMD----IQEFPDLKGTTSLEILTLTRAGIRLLPS 293
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSA 374
+S+N I L + LEE+ HN I + D F L SL +
Sbjct: 294 GMCQQLPRLRVLELSHNQIEELPSLHR--CQKLEEIGLQHNRIWEIGADTFSQLSSLQAL 351
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDN 410
DLS+N I +++ + S T++ S++K+ L DN
Sbjct: 352 DLSWNAIRSIHPEAFS----TLH---SLVKLDLTDN 380
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 11/222 (4%)
Query: 207 DIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
D++ N L L G L+ L L L+ N+++ Q GL L ++ L +NQ+ +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 266 SLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXX 324
E L ++ + + LRLD N I + +I
Sbjct: 80 --EALWELPS-LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPAL 136
Query: 325 XXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDK-DFHGLPSLCSADLSFNKIHT 383
++ N I+ + + + L SL L H+N I L F GL +L + DL++NK+
Sbjct: 137 QAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE 196
Query: 384 VNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + R N + +I + NP+L H Y+
Sbjct: 197 FPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 91.9 bits (218), Expect = 5e-18
Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 9/283 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 58 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + ++ N ++ +
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLS 185
++ + +N+LQ P ++ + LQ L F+ NNIK++ E L++ I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I+F+ + F KL L + L+ SL L LT + +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 297
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L RL V++LSHNQI L SL +E E+ L HN I+
Sbjct: 298 QLPRLRVLELSHNQIEELP-SLHRCQKLE----EIGLQHNRIW 335
Score = 81.8 bits (193), Expect = 6e-15
Identities = 67/261 (25%), Positives = 125/261 (47%), Gaps = 6/261 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F+++
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L L + +N+I + + L+ + L NKL A+R L L+ + + NN+K+
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 122 IENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNL 179
I + +Q IH N +Q + S + +P L +L G +I+ + L+ + +L
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSL 278
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ L+ I L + +L L++++N+++ L SL + L + L HN + E
Sbjct: 279 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEI 337
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L L +DLS N I
Sbjct: 338 GADTFSQLSSLQALDLSWNAI 358
Score = 67.3 bits (157), Expect = 1e-10
Identities = 63/254 (24%), Positives = 121/254 (47%), Gaps = 10/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L H + L +++TLDL NK+ + R + L
Sbjct: 149 IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRL 207
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLK 120
+ L +N I I + A L+ +H N + + A + L L + +N A +++
Sbjct: 208 QELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQ 267
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
+ T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L
Sbjct: 268 EFPDLKGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKL 324
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
IGL N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T
Sbjct: 325 EEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTT 384
Query: 239 FSLQEIKGLRRLSV 252
L + GL L +
Sbjct: 385 LPLAGLGGLMHLKL 398
Score = 61.3 bits (142), Expect = 9e-09
Identities = 90/396 (22%), Positives = 162/396 (40%), Gaps = 42/396 (10%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 81 ALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
AL + L+ + L N ++ + + L L ++++ N L E+P +A
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL----TEIPVRA------- 129
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDD 196
L +P+LQ++ N I + D Q +L+ + L N+I+ L
Sbjct: 130 ------------LNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
F L LD+ YN+L+ ++R+L L+ L +N + + G L I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 257 HNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXX 315
N I + + + L + T L +D I+ +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMD----IQEFPDLKGTTSLEILTLTRAGIRLLPS 293
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSA 374
+S+N I L + LEE+ HN I + D F L SL +
Sbjct: 294 GMCQQLPRLRVLELSHNQIEELPSLHR--CQKLEEIGLQHNRIWEIGADTFSQLSSLQAL 351
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDN 410
DLS+N I +++ + S T++ S++K+ L DN
Sbjct: 352 DLSWNAIRSIHPEAFS----TLH---SLVKLDLTDN 380
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 11/222 (4%)
Query: 207 DIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
D++ N L L G L+ L L L+ N+++ Q GL L ++ L +NQ+ +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 266 SLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXX 324
E L ++ + + LRLD N I + +I
Sbjct: 80 --EALWELPS-LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPAL 136
Query: 325 XXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDK-DFHGLPSLCSADLSFNKIHT 383
++ N I+ + + + L SL L H+N I L F GL +L + DL++NK+
Sbjct: 137 QAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE 196
Query: 384 VNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + R N + +I + NP+L H Y+
Sbjct: 197 FPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 91.9 bits (218), Expect = 5e-18
Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 9/283 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 58 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 117
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + ++ N ++ +
Sbjct: 118 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLS 185
++ + +N+LQ P ++ + LQ L F+ NNIK++ E L++ I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I+F+ + F KL L + L+ SL L LT + +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 297
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L RL V++LSHNQI L SL +E E+ L HN I+
Sbjct: 298 QLPRLRVLELSHNQIEELP-SLHRCQKLE----EIGLQHNRIW 335
Score = 81.8 bits (193), Expect = 6e-15
Identities = 67/261 (25%), Positives = 125/261 (47%), Gaps = 6/261 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F+++
Sbjct: 100 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 159
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L L + +N+I + + L+ + L NKL A+R L L+ + + NN+K+
Sbjct: 160 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 219
Query: 122 IENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNL 179
I + +Q IH N +Q + S + +P L +L G +I+ + L+ + +L
Sbjct: 220 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSL 278
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ L+ I L + +L L++++N+++ L SL + L + L HN + E
Sbjct: 279 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEI 337
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L L +DLS N I
Sbjct: 338 GADTFSQLSSLQALDLSWNAI 358
Score = 67.3 bits (157), Expect = 1e-10
Identities = 63/254 (24%), Positives = 121/254 (47%), Gaps = 10/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L H + L +++TLDL NK+ + R + L
Sbjct: 149 IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRL 207
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLK 120
+ L +N I I + A L+ +H N + + A + L L + +N A +++
Sbjct: 208 QELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQ 267
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
+ T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L
Sbjct: 268 EFPDLKGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKL 324
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
IGL N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T
Sbjct: 325 EEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTT 384
Query: 239 FSLQEIKGLRRLSV 252
L + GL L +
Sbjct: 385 LPLAGLGGLMHLKL 398
Score = 61.3 bits (142), Expect = 9e-09
Identities = 90/396 (22%), Positives = 162/396 (40%), Gaps = 42/396 (10%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +
Sbjct: 21 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 80
Query: 81 ALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
AL + L+ + L N ++ + + L L ++++ N L E+P +A
Sbjct: 81 ALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL----TEIPVRA------- 129
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDD 196
L +P+LQ++ N I + D Q +L+ + L N+I+ L
Sbjct: 130 ------------LNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 177
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
F L LD+ YN+L+ ++R+L L+ L +N + + G L I
Sbjct: 178 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 237
Query: 257 HNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXX 315
N I + + + L + T L +D I+ +
Sbjct: 238 DNPIQFVGRSAFQYLPKLHTLSLNGAMD----IQEFPDLKGTTSLEILTLTRAGIRLLPS 293
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSA 374
+S+N I L + LEE+ HN I + D F L SL +
Sbjct: 294 GMCQQLPRLRVLELSHNQIEELPSLHR--CQKLEEIGLQHNRIWEIGADTFSQLSSLQAL 351
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDN 410
DLS+N I +++ + S T++ S++K+ L DN
Sbjct: 352 DLSWNAIRSIHPEAFS----TLH---SLVKLDLTDN 380
Score = 42.7 bits (96), Expect = 0.003
Identities = 52/222 (23%), Positives = 89/222 (40%), Gaps = 11/222 (4%)
Query: 207 DIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
D++ N L L G L+ L L L+ N+++ Q GL L ++ L +NQ+ +
Sbjct: 20 DLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPA 79
Query: 266 SLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXX 324
E L ++ + + LRLD N I + +I
Sbjct: 80 --EALWELPS-LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPAL 136
Query: 325 XXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDK-DFHGLPSLCSADLSFNKIHT 383
++ N I+ + + + L SL L H+N I L F GL +L + DL++NK+
Sbjct: 137 QAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQE 196
Query: 384 VNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + R N + +I + NP+L H Y+
Sbjct: 197 FPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 238
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 91.9 bits (218), Expect = 5e-18
Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 9/283 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 110 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 169
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + ++ N ++ +
Sbjct: 170 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 229
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLS 185
++ + +N+LQ P ++ + LQ L F+ NNIK++ E L++ I
Sbjct: 230 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 289
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I+F+ + F KL L + L+ SL L LT + +
Sbjct: 290 DNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 349
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L RL V++LSHNQI L SL +E E+ L HN I+
Sbjct: 350 QLPRLRVLELSHNQIEELP-SLHRCQKLE----EIGLQHNRIW 387
Score = 81.8 bits (193), Expect = 6e-15
Identities = 67/261 (25%), Positives = 125/261 (47%), Gaps = 6/261 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F+++
Sbjct: 152 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 211
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L L + +N+I + + L+ + L NKL A+R L L+ + + NN+K+
Sbjct: 212 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 271
Query: 122 IENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNL 179
I + +Q IH N +Q + S + +P L +L G +I+ + L+ + +L
Sbjct: 272 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSL 330
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ L+ I L + +L L++++N+++ L SL + L + L HN + E
Sbjct: 331 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEI 389
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L L +DLS N I
Sbjct: 390 GADTFSQLSSLQALDLSWNAI 410
Score = 67.3 bits (157), Expect = 1e-10
Identities = 63/254 (24%), Positives = 121/254 (47%), Gaps = 10/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L H + L +++TLDL NK+ + R + L
Sbjct: 201 IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRL 259
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLK 120
+ L +N I I + A L+ +H N + + A + L L + +N A +++
Sbjct: 260 QELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQ 319
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
+ T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L
Sbjct: 320 EFPDLKGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKL 376
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
IGL N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T
Sbjct: 377 EEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTT 436
Query: 239 FSLQEIKGLRRLSV 252
L + GL L +
Sbjct: 437 LPLAGLGGLMHLKL 450
Score = 64.9 bits (151), Expect = 7e-10
Identities = 92/402 (22%), Positives = 164/402 (40%), Gaps = 42/402 (10%)
Query: 15 LVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI 74
L Y L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+
Sbjct: 67 LTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 126
Query: 75 SEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAK 131
I +AL + L+ + L N ++ + + L L ++++ N L E+P +A
Sbjct: 127 GGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL----TEIPVRA- 181
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIE 190
L +P+LQ++ N I + D Q +L+ + L N+I+
Sbjct: 182 ------------------LNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 223
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
L F L LD+ YN+L+ ++R+L L+ L +N + + G L
Sbjct: 224 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLL 283
Query: 251 SVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX 309
I N I + + + L + T L +D
Sbjct: 284 QTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD----IQEFPDLKGTTSLEILTLTRAG 339
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGL 368
I+ + +S+N I L + LEE+ HN I + D F L
Sbjct: 340 IRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR--CQKLEEIGLQHNRIWEIGADTFSQL 397
Query: 369 PSLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDN 410
SL + DLS+N I +++ + S T++ S++K+ L DN
Sbjct: 398 SSLQALDLSWNAIRSIHPEAFS----TLH---SLVKLDLTDN 432
Score = 45.2 bits (102), Expect = 6e-04
Identities = 54/225 (24%), Positives = 91/225 (40%), Gaps = 11/225 (4%)
Query: 204 AELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
A LD++ N L L G L+ L L L+ N+++ Q GL L ++ L +NQ+
Sbjct: 69 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGG 128
Query: 263 LTGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXX 321
+ E L ++ + + LRLD N I + +I
Sbjct: 129 IPA--EALWELPS-LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNL 185
Query: 322 XXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDK-DFHGLPSLCSADLSFNK 380
++ N I+ + + + L SL L H+N I L F GL +L + DL++NK
Sbjct: 186 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 245
Query: 381 IHTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + + R N + +I + NP+L H Y+
Sbjct: 246 LQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 290
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 91.9 bits (218), Expect = 5e-18
Identities = 78/283 (27%), Positives = 132/283 (46%), Gaps = 9/283 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 71 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 130
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + ++ N ++ +
Sbjct: 131 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHS 190
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLS 185
++ + +N+LQ P ++ + LQ L F+ NNIK++ E L++ I
Sbjct: 191 FEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFY 250
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I+F+ + F KL L + L+ SL L LT + +
Sbjct: 251 DNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQ 310
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L RL V++LSHNQI L SL +E E+ L HN I+
Sbjct: 311 QLPRLRVLELSHNQIEELP-SLHRCQKLE----EIGLQHNRIW 348
Score = 81.8 bits (193), Expect = 6e-15
Identities = 67/261 (25%), Positives = 125/261 (47%), Gaps = 6/261 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F+++
Sbjct: 113 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTS 172
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L L + +N+I + + L+ + L NKL A+R L L+ + + NN+K+
Sbjct: 173 LVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKA 232
Query: 122 IENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNL 179
I + +Q IH N +Q + S + +P L +L G +I+ + L+ + +L
Sbjct: 233 IPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSL 291
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ L+ I L + +L L++++N+++ L SL + L + L HN + E
Sbjct: 292 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEI 350
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L L +DLS N I
Sbjct: 351 GADTFSQLSSLQALDLSWNAI 371
Score = 67.3 bits (157), Expect = 1e-10
Identities = 63/254 (24%), Positives = 121/254 (47%), Gaps = 10/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L H + L +++TLDL NK+ + R + L
Sbjct: 162 IPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNKLQEFPVA-IRTLGRL 220
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLK 120
+ L +N I I + A L+ +H N + + A + L L + +N A +++
Sbjct: 221 QELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQ 280
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
+ T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L
Sbjct: 281 EFPDLKGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKL 337
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
IGL N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T
Sbjct: 338 EEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTT 397
Query: 239 FSLQEIKGLRRLSV 252
L + GL L +
Sbjct: 398 LPLAGLGGLMHLKL 411
Score = 64.9 bits (151), Expect = 7e-10
Identities = 92/402 (22%), Positives = 164/402 (40%), Gaps = 42/402 (10%)
Query: 15 LVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI 74
L Y L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+
Sbjct: 28 LTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQL 87
Query: 75 SEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAK 131
I +AL + L+ + L N ++ + + L L ++++ N L E+P +A
Sbjct: 88 GGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNAL----TEIPVRA- 142
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIE 190
L +P+LQ++ N I + D Q +L+ + L N+I+
Sbjct: 143 ------------------LNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQ 184
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
L F L LD+ YN+L+ ++R+L L+ L +N + + G L
Sbjct: 185 HLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLL 244
Query: 251 SVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX 309
I N I + + + L + T L +D
Sbjct: 245 QTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMD----IQEFPDLKGTTSLEILTLTRAG 300
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGL 368
I+ + +S+N I L + LEE+ HN I + D F L
Sbjct: 301 IRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR--CQKLEEIGLQHNRIWEIGADTFSQL 358
Query: 369 PSLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDN 410
SL + DLS+N I +++ + S T++ S++K+ L DN
Sbjct: 359 SSLQALDLSWNAIRSIHPEAFS----TLH---SLVKLDLTDN 393
Score = 45.2 bits (102), Expect = 6e-04
Identities = 54/225 (24%), Positives = 91/225 (40%), Gaps = 11/225 (4%)
Query: 204 AELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
A LD++ N L L G L+ L L L+ N+++ Q GL L ++ L +NQ+
Sbjct: 30 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGG 89
Query: 263 LTGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXX 321
+ E L ++ + + LRLD N I + +I
Sbjct: 90 IPA--EALWELPS-LQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNL 146
Query: 322 XXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDK-DFHGLPSLCSADLSFNK 380
++ N I+ + + + L SL L H+N I L F GL +L + DL++NK
Sbjct: 147 PALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDLNYNK 206
Query: 381 IHTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + + R N + +I + NP+L H Y+
Sbjct: 207 LQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYD 251
>AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple receptor
protein.
Length = 951
Score = 91.5 bits (217), Expect = 7e-18
Identities = 95/352 (26%), Positives = 154/352 (43%), Gaps = 13/352 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNT 98
+ LD+ N IT+L E+ F++ LE L +A N +S I AL K LK + L N+L T
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 99 L-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ + A+R L L+ + ++AN++ S+ + +++ + N L +P L +P+L
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
Q+L N I S+ D +L+ + L NKI L++ F + L LD++YN L
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS-LENLVDVE 274
++++ SL+ L N ++ G L I L N +S + S NL D+
Sbjct: 240 FPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLH 299
Query: 275 TRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHI 334
+ V+ + I I +SYN+I
Sbjct: 300 SLVIR----GASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNI 355
Query: 335 TTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
L S +LEE+ N I + + F GL SL DLS N IH ++
Sbjct: 356 RDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIH 405
Score = 80.2 bits (189), Expect = 2e-14
Identities = 59/245 (24%), Positives = 112/245 (45%), Gaps = 4/245 (1%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L +N L +P ++ L +++L L N IT + E+ F + +L HL + DN ++E+
Sbjct: 111 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 170
Query: 80 DALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
L L+ + L +NK++++ + A +L L + ++ N ++ + ++ +
Sbjct: 171 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETL 230
Query: 137 HAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD 195
++N L P +K PSL+ L F+ N+I + + L+R I L N + F+
Sbjct: 231 DLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNS 290
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L L I + +L L L LT ++ + + L +DL
Sbjct: 291 AFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDL 350
Query: 256 SHNQI 260
S+N I
Sbjct: 351 SYNNI 355
Score = 76.2 bits (179), Expect = 3e-13
Identities = 65/257 (25%), Positives = 117/257 (45%), Gaps = 4/257 (1%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F L + + L DNSL E+P H L +LP ++ L L NKI+ + + F ++ L
Sbjct: 146 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 205
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + +N+I + + L+ + L N L A++ L+ + ++N++ I +
Sbjct: 206 LHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPD 265
Query: 125 ELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
++ IH N L + S + L SL G ++ L + +L +
Sbjct: 266 GAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLT 325
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
L+ KI + + E + L LD++YN ++ L S +L ++L N + +
Sbjct: 326 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALEEISLQRNQIYQIKEGT 384
Query: 244 IKGLRRLSVIDLSHNQI 260
+GL L ++DLS N I
Sbjct: 385 FQGLISLRILDLSRNLI 401
Score = 60.1 bits (139), Expect = 2e-08
Identities = 60/254 (23%), Positives = 115/254 (45%), Gaps = 8/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N + L +H L +++TLDL N + + + + L
Sbjct: 192 IPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQA-IKARPSL 250
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L N IS I A L+ +HL N L+ + N A +L DL + I ++
Sbjct: 251 KELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQ 310
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
L T ++ + ++ S+P++L + L++L NNI+ L + L
Sbjct: 311 QFPNL-TGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALE 368
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEF 239
I L N+I + + F L LD++ N + ++ + +L + L+++ N +T F
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSF 428
Query: 240 SLQEIKGLRRLSVI 253
+ + GL +L ++
Sbjct: 429 PTEGLNGLNQLKLV 442
>AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled receptor
48 protein.
Length = 951
Score = 91.1 bits (216), Expect = 1e-17
Identities = 95/352 (26%), Positives = 154/352 (43%), Gaps = 13/352 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNT 98
+ LD+ N IT+L E+ F++ LE L +A N +S I AL K LK + L N+L T
Sbjct: 60 QALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKT 119
Query: 99 L-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ + A+R L L+ + ++AN++ S+ + +++ + N L +P L +P+L
Sbjct: 120 VPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
Q+L N I S+ D +L+ + L NKI L++ F + L LD++YN L
Sbjct: 180 QALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGE 239
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL-ENLVDVE 274
++++ SL+ L N ++ G L I L N +S + S NL D+
Sbjct: 240 FPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLH 299
Query: 275 TRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHI 334
+ V+ + I I +SYN+I
Sbjct: 300 SLVIR----GASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNI 355
Query: 335 TTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
L S +LEE+ N I + + F GL SL DLS N IH ++
Sbjct: 356 RDL--PSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIH 405
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/245 (23%), Positives = 111/245 (45%), Gaps = 4/245 (1%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L +N L +P ++ L +++L L N IT + E+ F + +L HL + DN ++E+
Sbjct: 111 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 170
Query: 80 DALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
L L+ + L +NK++++ + A +L L + ++ N ++ + ++ +
Sbjct: 171 HPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETL 230
Query: 137 HAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD 195
++N L P +K PSL+ L F+ N+I + + L+R I L N + F+
Sbjct: 231 DLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNS 290
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
L L I + +L L L LT ++ + + L +DL
Sbjct: 291 ASHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDL 350
Query: 256 SHNQI 260
S+N I
Sbjct: 351 SYNNI 355
Score = 75.8 bits (178), Expect = 4e-13
Identities = 64/257 (24%), Positives = 117/257 (45%), Gaps = 4/257 (1%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F L + + L DNSL E+P H L +LP ++ L L NKI+ + + F ++ L
Sbjct: 146 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 205
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + +N+I + + L+ + L N L A++ L+ + ++N++ I +
Sbjct: 206 LHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQAIKARPSLKELGFHSNSISVIPD 265
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
++ IH N L + + + L SL G ++ L + +L +
Sbjct: 266 GAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLT 325
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
L+ KI + + E + L LD++YN ++ L S +L ++L N + +
Sbjct: 326 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALEEISLQRNQIYQIKEGT 384
Query: 244 IKGLRRLSVIDLSHNQI 260
+GL L ++DLS N I
Sbjct: 385 FQGLISLRILDLSRNLI 401
Score = 57.2 bits (132), Expect = 1e-07
Identities = 60/254 (23%), Positives = 114/254 (44%), Gaps = 8/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N + L +H L +++TLDL N + + + + L
Sbjct: 192 IPDFAFTNLSSLVVLHLHNNKIRGLSQHCFDGLDNLETLDLSYNNLGEFPQA-IKARPSL 250
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L N IS I A L+ +HL N L+ + N A +L DL + I ++
Sbjct: 251 KELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSASHNLSDLHSLVIRGASMVQ 310
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
L T ++ + ++ S+P++L + L++L NNI+ L + L
Sbjct: 311 QFPNL-TGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALE 368
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEF 239
I L N+I + + F L LD++ N + ++ + +L + L+++ N +T F
Sbjct: 369 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSF 428
Query: 240 SLQEIKGLRRLSVI 253
+ GL +L ++
Sbjct: 429 PTEGPNGLNQLKLV 442
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 90.6 bits (215), Expect = 1e-17
Identities = 72/252 (28%), Positives = 132/252 (52%), Gaps = 8/252 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
+++N L L L+ LP + LD+ N++T L R+++ L+ L V+ N++ + ++
Sbjct: 89 ISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLKILPEE 146
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ LK ++L N+L ++ L +LE + ++ N+L ++ + + ++L + +
Sbjct: 147 ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL-NLS 205
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
NEL+SLP+++ M L+ L N ++++ L +L + L NK+ FL +F
Sbjct: 206 SNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP--EFPS 263
Query: 200 AEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L EL + N+++ L L+ L S+ L+L N + EI LR L +DLS+N
Sbjct: 264 CSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVP-DEIILLRSLERLDLSNN 322
Query: 259 QISLLTGSLENL 270
IS L SL NL
Sbjct: 323 DISSLPYSLGNL 334
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/273 (23%), Positives = 132/273 (48%), Gaps = 18/273 (6%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L+ + +N + L L+HL + LDL NK+ + +E ++ LE L +
Sbjct: 261 FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDL 319
Query: 70 ADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK 129
++N IS + LK + L N L T+ + E + + +K ++ P++
Sbjct: 320 SNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIK---DDGPSQ 376
Query: 130 AKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYF--YGNNIKSL--DETLQ--KSRNLMRI 182
++ +A +LPS+ ++ + ++ +L Y + +L DE KS + I
Sbjct: 377 SE------SATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSI 430
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ + K E ++++D+++N+L +++ L L+ L +L+L +N++ +
Sbjct: 431 NFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLP-E 489
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
E++ L RL I+LS N+ +L L + +ET
Sbjct: 490 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLET 522
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 65/110 (59%), Gaps = 6/110 (5%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
+L ++ +S NK++ LT DD L LDI N+L L ++R L++L+ LN++HN +
Sbjct: 83 DLTKLIISNNKLQSLT-DDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL- 140
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ +EI LR L + L HN+++ ++ E L ++E +L L +NH+
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLE----DLDLSNNHL 186
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/254 (22%), Positives = 112/254 (44%), Gaps = 35/254 (13%)
Query: 35 QHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA-LPKGLKHVHLGI 93
+ L +++ LDL N +T + F + L L ++ N++ + + K LKH+
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPAS-FSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLK--------SIENELPTKAKKMQLIHAAH----- 140
N L T+ L ++ LE +++ N L+ S+ EL +++++ A H
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 141 ---------NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
N+L+S+P ++ L+ SL+ L N+I SL +L + +L + L N +
Sbjct: 290 SILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL-GNLHLKFLALEGNPLRT 348
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT--EFSLQEIKGLRR 249
+ ++ ++ + LKYL ++ + + T MT S I +
Sbjct: 349 IRREIISKGTQ--------EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIIT 400
Query: 250 LSVIDLSHNQISLL 263
L ++D S Q +L+
Sbjct: 401 LKILDYSDKQATLI 414
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/165 (23%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 4 VLKESVF--TKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI 61
++ + VF K ++V + + N L E+P+ +++ V +DL NK++ ++ E +
Sbjct: 413 LIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE-LCVL 471
Query: 62 QELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
Q+L L + +N ++ + E ++L + L+ ++L N+ L L + LE I I+ N +
Sbjct: 472 QKLTFLDLRNNFLNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 530
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
S++ + + + + +N+L +P +L +L++L GN
Sbjct: 531 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 575
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N L I EL +K+ + +N L SLP +++ + LQ++ N K L E L
Sbjct: 456 LSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ L I +S N++ + E L LD+ N+L + L + +LR L L
Sbjct: 515 YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDG 574
Query: 234 N 234
N
Sbjct: 575 N 575
Score = 33.5 bits (73), Expect = 2.0
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTVNYDL 388
+S N + +L + + LP+L L H N +T L L +L ++S NK+ + +
Sbjct: 89 ISNNKLQSLTDDLR-LLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEE- 146
Query: 389 VSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTAPIL 448
I + ++ +YLQ N + C +E ++ E L+ + +T A ++ L
Sbjct: 147 -------ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSL 199
Query: 449 MR 450
+R
Sbjct: 200 VR 201
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 90.6 bits (215), Expect = 1e-17
Identities = 72/252 (28%), Positives = 132/252 (52%), Gaps = 8/252 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
+++N L L L+ LP + LD+ N++T L R+++ L+ L V+ N++ + ++
Sbjct: 68 ISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLKILPEE 125
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ LK ++L N+L ++ L +LE + ++ N+L ++ + + ++L + +
Sbjct: 126 ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL-NLS 184
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
NEL+SLP+++ M L+ L N ++++ L +L + L NK+ FL +F
Sbjct: 185 SNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP--EFPS 242
Query: 200 AEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L EL + N+++ L L+ L S+ L+L N + EI LR L +DLS+N
Sbjct: 243 CSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVP-DEIILLRSLERLDLSNN 301
Query: 259 QISLLTGSLENL 270
IS L SL NL
Sbjct: 302 DISSLPYSLGNL 313
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/273 (23%), Positives = 132/273 (48%), Gaps = 18/273 (6%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L+ + +N + L L+HL + LDL NK+ + +E ++ LE L +
Sbjct: 240 FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDL 298
Query: 70 ADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK 129
++N IS + LK + L N L T+ + E + + +K ++ P++
Sbjct: 299 SNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIK---DDGPSQ 355
Query: 130 AKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYF--YGNNIKSL--DETLQ--KSRNLMRI 182
++ +A +LPS+ ++ + ++ +L Y + +L DE KS + I
Sbjct: 356 SE------SATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSI 409
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ + K E ++++D+++N+L +++ L L+ L +L+L +N++ +
Sbjct: 410 NFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLP-E 468
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
E++ L RL I+LS N+ +L L + +ET
Sbjct: 469 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLET 501
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 65/110 (59%), Gaps = 6/110 (5%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
+L ++ +S NK++ LT DD L LDI N+L L ++R L++L+ LN++HN +
Sbjct: 62 DLTKLIISNNKLQSLT-DDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL- 119
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ +EI LR L + L HN+++ ++ E L ++E +L L +NH+
Sbjct: 120 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLE----DLDLSNNHL 165
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/254 (22%), Positives = 112/254 (44%), Gaps = 35/254 (13%)
Query: 35 QHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA-LPKGLKHVHLGI 93
+ L +++ LDL N +T + F + L L ++ N++ + + K LKH+
Sbjct: 150 EQLSNLEDLDLSNNHLTTVPAS-FSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 208
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLK--------SIENELPTKAKKMQLIHAAH----- 140
N L T+ L ++ LE +++ N L+ S+ EL +++++ A H
Sbjct: 209 NLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLN 268
Query: 141 ---------NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
N+L+S+P ++ L+ SL+ L N+I SL +L + +L + L N +
Sbjct: 269 SILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL-GNLHLKFLALEGNPLRT 327
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT--EFSLQEIKGLRR 249
+ ++ ++ + LKYL ++ + + T MT S I +
Sbjct: 328 IRREIISKGTQ--------EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIIT 379
Query: 250 LSVIDLSHNQISLL 263
L ++D S Q +L+
Sbjct: 380 LKILDYSDKQATLI 393
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/165 (23%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 4 VLKESVF--TKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI 61
++ + VF K ++V + + N L E+P+ +++ V +DL NK++ ++ E +
Sbjct: 392 LIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE-LCVL 450
Query: 62 QELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
Q+L L + +N ++ + E ++L + L+ ++L N+ L L + LE I I+ N +
Sbjct: 451 QKLTFLDLRNNFLNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 509
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
S++ + + + + +N+L +P +L +L++L GN
Sbjct: 510 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 554
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N L I EL +K+ + +N L SLP +++ + LQ++ N K L E L
Sbjct: 435 LSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 493
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ L I +S N++ + E L LD+ N+L + L + +LR L L
Sbjct: 494 YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDG 553
Query: 234 N 234
N
Sbjct: 554 N 554
Score = 33.5 bits (73), Expect = 2.0
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTVNYDL 388
+S N + +L + + LP+L L H N +T L L +L ++S NK+ + +
Sbjct: 68 ISNNKLQSLTDDLR-LLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEE- 125
Query: 389 VSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTAPIL 448
I + ++ +YLQ N + C +E ++ E L+ + +T A ++ L
Sbjct: 126 -------ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSL 178
Query: 449 MR 450
+R
Sbjct: 179 VR 180
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 90.6 bits (215), Expect = 1e-17
Identities = 72/252 (28%), Positives = 132/252 (52%), Gaps = 8/252 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
+++N L L L+ LP + LD+ N++T L R+++ L+ L V+ N++ + ++
Sbjct: 89 ISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLKILPEE 146
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ LK ++L N+L ++ L +LE + ++ N+L ++ + + ++L + +
Sbjct: 147 ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL-NLS 205
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
NEL+SLP+++ M L+ L N ++++ L +L + L NK+ FL +F
Sbjct: 206 SNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP--EFPS 263
Query: 200 AEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L EL + N+++ L L+ L S+ L+L N + EI LR L +DLS+N
Sbjct: 264 CSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVP-DEIILLRSLERLDLSNN 322
Query: 259 QISLLTGSLENL 270
IS L SL NL
Sbjct: 323 DISSLPYSLGNL 334
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/273 (23%), Positives = 132/273 (48%), Gaps = 18/273 (6%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L+ + +N + L L+HL + LDL NK+ + +E ++ LE L +
Sbjct: 261 FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDL 319
Query: 70 ADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK 129
++N IS + LK + L N L T+ + E + + +K ++ P++
Sbjct: 320 SNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIK---DDGPSQ 376
Query: 130 AKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYF--YGNNIKSL--DETLQ--KSRNLMRI 182
++ +A +LPS+ ++ + ++ +L Y + +L DE KS + I
Sbjct: 377 SE------SATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSI 430
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ + K E ++++D+++N+L +++ L L+ L +L+L +N++ +
Sbjct: 431 NFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLP-E 489
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
E++ L RL I+LS N+ +L L + +ET
Sbjct: 490 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLET 522
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 65/110 (59%), Gaps = 6/110 (5%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
+L ++ +S NK++ LT DD L LDI N+L L ++R L++L+ LN++HN +
Sbjct: 83 DLTKLIISNNKLQSLT-DDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL- 140
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ +EI LR L + L HN+++ ++ E L ++E +L L +NH+
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLE----DLDLSNNHL 186
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/254 (22%), Positives = 112/254 (44%), Gaps = 35/254 (13%)
Query: 35 QHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA-LPKGLKHVHLGI 93
+ L +++ LDL N +T + F + L L ++ N++ + + K LKH+
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPAS-FSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLK--------SIENELPTKAKKMQLIHAAH----- 140
N L T+ L ++ LE +++ N L+ S+ EL +++++ A H
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 141 ---------NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
N+L+S+P ++ L+ SL+ L N+I SL +L + +L + L N +
Sbjct: 290 SILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL-GNLHLKFLALEGNPLRT 348
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT--EFSLQEIKGLRR 249
+ ++ ++ + LKYL ++ + + T MT S I +
Sbjct: 349 IRREIISKGTQ--------EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIIT 400
Query: 250 LSVIDLSHNQISLL 263
L ++D S Q +L+
Sbjct: 401 LKILDYSDKQATLI 414
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/165 (23%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 4 VLKESVF--TKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI 61
++ + VF K ++V + + N L E+P+ +++ V +DL NK++ ++ E +
Sbjct: 413 LIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE-LCVL 471
Query: 62 QELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
Q+L L + +N ++ + E ++L + L+ ++L N+ L L + LE I I+ N +
Sbjct: 472 QKLTFLDLRNNFLNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 530
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
S++ + + + + +N+L +P +L +L++L GN
Sbjct: 531 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 575
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N L I EL +K+ + +N L SLP +++ + LQ++ N K L E L
Sbjct: 456 LSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ L I +S N++ + E L LD+ N+L + L + +LR L L
Sbjct: 515 YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDG 574
Query: 234 N 234
N
Sbjct: 575 N 575
Score = 33.5 bits (73), Expect = 2.0
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTVNYDL 388
+S N + +L + + LP+L L H N +T L L +L ++S NK+ + +
Sbjct: 89 ISNNKLQSLTDDLR-LLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEE- 146
Query: 389 VSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTAPIL 448
I + ++ +YLQ N + C +E ++ E L+ + +T A ++ L
Sbjct: 147 -------ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSL 199
Query: 449 MR 450
+R
Sbjct: 200 VR 201
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 90.6 bits (215), Expect = 1e-17
Identities = 72/252 (28%), Positives = 132/252 (52%), Gaps = 8/252 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
+++N L L L+ LP + LD+ N++T L R+++ L+ L V+ N++ + ++
Sbjct: 89 ISNNKLQSLTDD-LRLLPALTVLDIHDNQLTSLPSA-IRELENLQKLNVSHNKLKILPEE 146
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ LK ++L N+L ++ L +LE + ++ N+L ++ + + ++L + +
Sbjct: 147 ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRL-NLS 205
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
NEL+SLP+++ M L+ L N ++++ L +L + L NK+ FL +F
Sbjct: 206 SNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP--EFPS 263
Query: 200 AEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L EL + N+++ L L+ L S+ L+L N + EI LR L +DLS+N
Sbjct: 264 CSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVP-DEIILLRSLERLDLSNN 322
Query: 259 QISLLTGSLENL 270
IS L SL NL
Sbjct: 323 DISSLPYSLGNL 334
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/273 (23%), Positives = 132/273 (48%), Gaps = 18/273 (6%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L+ + +N + L L+HL + LDL NK+ + +E ++ LE L +
Sbjct: 261 FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDL 319
Query: 70 ADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK 129
++N IS + LK + L N L T+ + E + + +K ++ P++
Sbjct: 320 SNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSKIK---DDGPSQ 376
Query: 130 AKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYF--YGNNIKSL--DETLQ--KSRNLMRI 182
++ +A +LPS+ ++ + ++ +L Y + +L DE KS + I
Sbjct: 377 SE------SATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSI 430
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ + K E ++++D+++N+L +++ L L+ L +L+L +N++ +
Sbjct: 431 NFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLP-E 489
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
E++ L RL I+LS N+ +L L + +ET
Sbjct: 490 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLET 522
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/110 (33%), Positives = 65/110 (59%), Gaps = 6/110 (5%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
+L ++ +S NK++ LT DD L LDI N+L L ++R L++L+ LN++HN +
Sbjct: 83 DLTKLIISNNKLQSLT-DDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKL- 140
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ +EI LR L + L HN+++ ++ E L ++E +L L +NH+
Sbjct: 141 KILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLE----DLDLSNNHL 186
Score = 50.8 bits (116), Expect = 1e-05
Identities = 57/254 (22%), Positives = 112/254 (44%), Gaps = 35/254 (13%)
Query: 35 QHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA-LPKGLKHVHLGI 93
+ L +++ LDL N +T + F + L L ++ N++ + + K LKH+
Sbjct: 171 EQLSNLEDLDLSNNHLTTVPAS-FSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNS 229
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLK--------SIENELPTKAKKMQLIHAAH----- 140
N L T+ L ++ LE +++ N L+ S+ EL +++++ A H
Sbjct: 230 NLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLN 289
Query: 141 ---------NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
N+L+S+P ++ L+ SL+ L N+I SL +L + +L + L N +
Sbjct: 290 SILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL-GNLHLKFLALEGNPLRT 348
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT--EFSLQEIKGLRR 249
+ ++ ++ + LKYL ++ + + T MT S I +
Sbjct: 349 IRREIISKGTQ--------EVLKYLRSKIKDDGPSQSESATETAMTLPSESRVNIHAIIT 400
Query: 250 LSVIDLSHNQISLL 263
L ++D S Q +L+
Sbjct: 401 LKILDYSDKQATLI 414
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/165 (23%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 4 VLKESVF--TKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI 61
++ + VF K ++V + + N L E+P+ +++ V +DL NK++ ++ E +
Sbjct: 413 LIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE-LCVL 471
Query: 62 QELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
Q+L L + +N ++ + E ++L + L+ ++L N+ L L + LE I I+ N +
Sbjct: 472 QKLTFLDLRNNFLNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 530
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
S++ + + + + +N+L +P +L +L++L GN
Sbjct: 531 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 575
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N L I EL +K+ + +N L SLP +++ + LQ++ N K L E L
Sbjct: 456 LSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 514
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ L I +S N++ + E L LD+ N+L + L + +LR L L
Sbjct: 515 YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDG 574
Query: 234 N 234
N
Sbjct: 575 N 575
Score = 33.5 bits (73), Expect = 2.0
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTVNYDL 388
+S N + +L + + LP+L L H N +T L L +L ++S NK+ + +
Sbjct: 89 ISNNKLQSLTDDLR-LLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEE- 146
Query: 389 VSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTAPIL 448
I + ++ +YLQ N + C +E ++ E L+ + +T A ++ L
Sbjct: 147 -------ITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSL 199
Query: 449 MR 450
+R
Sbjct: 200 VR 201
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 88.6 bits (210), Expect = 5e-17
Identities = 72/278 (25%), Positives = 134/278 (48%), Gaps = 7/278 (2%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ SL N +PE+ LQ P +++LDL N I+++ F +Q L++L +++N+I+
Sbjct: 122 ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRIT 180
Query: 76 EIEK---DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
+E D L L V L N+++ + + L L+++ + N +K +E
Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 133 MQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIE 190
++ + N + L + +++ L NN+ +++ L R L ++ +S N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRR 249
++ D + ++L+ELD++YN+L L+ S L L LNL N +T + + L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 250 LSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
L +DL +N+IS T + +L L N I
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQI 398
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/336 (23%), Positives = 133/336 (39%), Gaps = 15/336 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
LP + N+L+ N +L L+ + +N N L I + L+ HN
Sbjct: 73 LPPDTAILDFSHNRLSNWNISLES-QTLQEVKMNYNELTEIPY-FGEPTSNITLLSLVHN 130
Query: 142 ELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE- 199
+ + + L+ P+L+SL N I + + L + LS N+I L F
Sbjct: 131 IIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNL 190
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+ L + + N + + + L L++L L N + +GL L + + N
Sbjct: 191 SSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 260 ISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXX-XXXXXXXXXXXXXXXXIQKIXXXX 317
IS L G+ L ++E EL L+HN++ I++I
Sbjct: 251 ISKLKDGAFFGLNNME----ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDA 306
Query: 318 XXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADL 376
+SYN +T L+E++ L LE L N +T + D F L +L + DL
Sbjct: 307 WEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
N+I + + G+ S+ K+ LQ N +
Sbjct: 367 RNNEISWA----IEDASEAFAGLTSLTKLILQGNQI 398
Score = 60.9 bits (141), Expect = 1e-08
Identities = 92/420 (21%), Positives = 172/420 (40%), Gaps = 28/420 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG----LKHVHLGI 93
P LD N+++ + Q L+ + + N+++EI P L VH I
Sbjct: 75 PDTAILDFSHNRLSNWNIS--LESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNII 132
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--K 151
++N AL+ LE + +++N + I+ + + ++ ++ ++N + +L +
Sbjct: 133 PEINAQ--ALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDN 189
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L SL + N + + + K +L + L N+I+ + F + L L + N
Sbjct: 190 LSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRN 249
Query: 212 ELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L +G+ L ++ L L HN +T + + GLR L + +S N I ++
Sbjct: 250 GISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEF 309
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX-IQKIXXXXXXXXXXXXXXXV 329
R+ EL L +N + + I +
Sbjct: 310 CQ---RLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 330 SYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N I+ +E+ S+ F L SL +LI N I ++ K F GL SL DL+ N I ++
Sbjct: 367 RNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQ 426
Query: 386 YDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTA 445
+ S++ + ++ L + +LCD HL L+ N + S +C P+ A
Sbjct: 427 ENAFSQTH--------LKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLA 478
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTE---EDFRDI 61
L ES F L L++ +L DN + + V + L +++TLDL N+I+ E E F +
Sbjct: 326 LDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGL 385
Query: 62 QELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
L L++ NQI I K A + L+H+ L N + ++ L+ + +N ++L
Sbjct: 386 TSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSL 445
Score = 47.2 bits (107), Expect = 2e-04
Identities = 47/228 (20%), Positives = 99/228 (43%), Gaps = 8/228 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + + L N + + Q L +++L + RN I+KL + F + +E L +
Sbjct: 213 KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEH 272
Query: 72 NQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N ++ + K L + L+ +++ N + ++ A L + ++ N L ++
Sbjct: 273 NNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFV 332
Query: 129 KAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNI----KSLDETLQKSRNLMRIG 183
++ ++ N + + + + + +LQ+L N I + E +L ++
Sbjct: 333 GLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLI 392
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL 231
L N+I+ +TK F E L LD+ N + + + S L+ L L
Sbjct: 393 LQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELIL 440
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK+ F L+ ++ L N+L + + L L ++ L + +N I +++ + + Q L
Sbjct: 254 LKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRL 313
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLK- 120
L ++ NQ++ +++ A L+ ++LG N++ + +G R L +L+ + + N +
Sbjct: 314 SELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISW 373
Query: 121 SIENELPTKAKKMQL--IHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKSR 177
+IE+ A L + N+++S+ + + SL+ L N I S+ E
Sbjct: 374 AIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQT 433
Query: 178 NLMRIGLSFNKI 189
+L + L+ + +
Sbjct: 434 HLKELILNTSSL 445
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 88.6 bits (210), Expect = 5e-17
Identities = 72/278 (25%), Positives = 134/278 (48%), Gaps = 7/278 (2%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ SL N +PE+ LQ P +++LDL N I+++ F +Q L++L +++N+I+
Sbjct: 122 ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRIT 180
Query: 76 EIEK---DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
+E D L L V L N+++ + + L L+++ + N +K +E
Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 133 MQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIE 190
++ + N + L + +++ L NN+ +++ L R L ++ +S N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRR 249
++ D + ++L+ELD++YN+L L+ S L L LNL N +T + + L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 250 LSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
L +DL +N+IS T + +L L N I
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQI 398
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/336 (23%), Positives = 133/336 (39%), Gaps = 15/336 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
LP + N+L+ N +L L+ + +N N L I + L+ HN
Sbjct: 73 LPPDTAILDFSHNRLSNWNISLES-QTLQEVKMNYNELTEIPY-FGEPTSNITLLSLVHN 130
Query: 142 ELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE- 199
+ + + L+ P+L+SL N I + + L + LS N+I L F
Sbjct: 131 IIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNL 190
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+ L + + N + + + L L++L L N + +GL L + + N
Sbjct: 191 SSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 260 ISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXX-XXXXXXXXXXXXXXXXIQKIXXXX 317
IS L G+ L ++E EL L+HN++ I++I
Sbjct: 251 ISKLKDGAFFGLNNME----ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDA 306
Query: 318 XXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADL 376
+SYN +T L+E++ L LE L N +T + D F L +L + DL
Sbjct: 307 WEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
N+I + + G+ S+ K+ LQ N +
Sbjct: 367 RNNEISWA----IEDASEAFAGLTSLTKLILQGNQI 398
Score = 60.9 bits (141), Expect = 1e-08
Identities = 92/420 (21%), Positives = 172/420 (40%), Gaps = 28/420 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG----LKHVHLGI 93
P LD N+++ + Q L+ + + N+++EI P L VH I
Sbjct: 75 PDTAILDFSHNRLSNWNIS--LESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNII 132
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--K 151
++N AL+ LE + +++N + I+ + + ++ ++ ++N + +L +
Sbjct: 133 PEINAQ--ALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDN 189
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L SL + N + + + K +L + L N+I+ + F + L L + N
Sbjct: 190 LSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRN 249
Query: 212 ELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L +G+ L ++ L L HN +T + + GLR L + +S N I ++
Sbjct: 250 GISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEF 309
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX-IQKIXXXXXXXXXXXXXXXV 329
R+ EL L +N + + I +
Sbjct: 310 CQ---RLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 330 SYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N I+ +E+ S+ F L SL +LI N I ++ K F GL SL DL+ N I ++
Sbjct: 367 RNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQ 426
Query: 386 YDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTA 445
+ S++ + ++ L + +LCD HL L+ N + S +C P+ A
Sbjct: 427 ENAFSQTH--------LKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLA 478
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTE---EDFRDI 61
L ES F L L++ +L DN + + V + L +++TLDL N+I+ E E F +
Sbjct: 326 LDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGL 385
Query: 62 QELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
L L++ NQI I K A + L+H+ L N + ++ L+ + +N ++L
Sbjct: 386 TSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSL 445
Score = 47.2 bits (107), Expect = 2e-04
Identities = 47/228 (20%), Positives = 99/228 (43%), Gaps = 8/228 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + + L N + + Q L +++L + RN I+KL + F + +E L +
Sbjct: 213 KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEH 272
Query: 72 NQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N ++ + K L + L+ +++ N + ++ A L + ++ N L ++
Sbjct: 273 NNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFV 332
Query: 129 KAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNI----KSLDETLQKSRNLMRIG 183
++ ++ N + + + + + +LQ+L N I + E +L ++
Sbjct: 333 GLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLI 392
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL 231
L N+I+ +TK F E L LD+ N + + + S L+ L L
Sbjct: 393 LQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELIL 440
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK+ F L+ ++ L N+L + + L L ++ L + +N I +++ + + Q L
Sbjct: 254 LKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRL 313
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLK- 120
L ++ NQ++ +++ A L+ ++LG N++ + +G R L +L+ + + N +
Sbjct: 314 SELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISW 373
Query: 121 SIENELPTKAKKMQL--IHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKSR 177
+IE+ A L + N+++S+ + + SL+ L N I S+ E
Sbjct: 374 AIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQT 433
Query: 178 NLMRIGLSFNKI 189
+L + L+ + +
Sbjct: 434 HLKELILNTSSL 445
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 88.6 bits (210), Expect = 5e-17
Identities = 72/278 (25%), Positives = 134/278 (48%), Gaps = 7/278 (2%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ SL N +PE+ LQ P +++LDL N I+++ F +Q L++L +++N+I+
Sbjct: 122 ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRIT 180
Query: 76 EIEK---DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
+E D L L V L N+++ + + L L+++ + N +K +E
Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 240
Query: 133 MQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIE 190
++ + N + L + +++ L NN+ +++ L R L ++ +S N IE
Sbjct: 241 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 300
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRR 249
++ D + ++L+ELD++YN+L L+ S L L LNL N +T + + L
Sbjct: 301 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 360
Query: 250 LSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
L +DL +N+IS T + +L L N I
Sbjct: 361 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQI 398
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/336 (23%), Positives = 133/336 (39%), Gaps = 15/336 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
LP + N+L+ N +L L+ + +N N L I + L+ HN
Sbjct: 73 LPPDTAILDFSHNRLSNWNISLES-QTLQEVKMNYNELTEIPY-FGEPTSNITLLSLVHN 130
Query: 142 ELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE- 199
+ + + L+ P+L+SL N I + + L + LS N+I L F
Sbjct: 131 IIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNL 190
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+ L + + N + + + L L++L L N + +GL L + + N
Sbjct: 191 SSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 250
Query: 260 ISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXX-XXXXXXXXXXXXXXXXIQKIXXXX 317
IS L G+ L ++E EL L+HN++ I++I
Sbjct: 251 ISKLKDGAFFGLNNME----ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDA 306
Query: 318 XXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADL 376
+SYN +T L+E++ L LE L N +T + D F L +L + DL
Sbjct: 307 WEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
N+I + + G+ S+ K+ LQ N +
Sbjct: 367 RNNEISWA----IEDASEAFAGLTSLTKLILQGNQI 398
Score = 60.9 bits (141), Expect = 1e-08
Identities = 92/420 (21%), Positives = 172/420 (40%), Gaps = 28/420 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG----LKHVHLGI 93
P LD N+++ + Q L+ + + N+++EI P L VH I
Sbjct: 75 PDTAILDFSHNRLSNWNIS--LESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNII 132
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--K 151
++N AL+ LE + +++N + I+ + + ++ ++ ++N + +L +
Sbjct: 133 PEINAQ--ALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDN 189
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L SL + N + + + K +L + L N+I+ + F + L L + N
Sbjct: 190 LSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRN 249
Query: 212 ELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L +G+ L ++ L L HN +T + + GLR L + +S N I ++
Sbjct: 250 GISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEF 309
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX-IQKIXXXXXXXXXXXXXXXV 329
R+ EL L +N + + I +
Sbjct: 310 CQ---RLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 366
Query: 330 SYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N I+ +E+ S+ F L SL +LI N I ++ K F GL SL DL+ N I ++
Sbjct: 367 RNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQ 426
Query: 386 YDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTA 445
+ S++ + ++ L + +LCD HL L+ N + S +C P+ A
Sbjct: 427 ENAFSQTH--------LKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLA 478
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTE---EDFRDI 61
L ES F L L++ +L DN + + V + L +++TLDL N+I+ E E F +
Sbjct: 326 LDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGL 385
Query: 62 QELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
L L++ NQI I K A + L+H+ L N + ++ L+ + +N ++L
Sbjct: 386 TSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSL 445
Score = 47.2 bits (107), Expect = 2e-04
Identities = 47/228 (20%), Positives = 99/228 (43%), Gaps = 8/228 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + + L N + + Q L +++L + RN I+KL + F + +E L +
Sbjct: 213 KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEH 272
Query: 72 NQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N ++ + K L + L+ +++ N + ++ A L + ++ N L ++
Sbjct: 273 NNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFV 332
Query: 129 KAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNI----KSLDETLQKSRNLMRIG 183
++ ++ N + + + + + +LQ+L N I + E +L ++
Sbjct: 333 GLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLI 392
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL 231
L N+I+ +TK F E L LD+ N + + + S L+ L L
Sbjct: 393 LQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELIL 440
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK+ F L+ ++ L N+L + + L L ++ L + +N I +++ + + Q L
Sbjct: 254 LKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRL 313
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLK- 120
L ++ NQ++ +++ A L+ ++LG N++ + +G R L +L+ + + N +
Sbjct: 314 SELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISW 373
Query: 121 SIENELPTKAKKMQL--IHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKSR 177
+IE+ A L + N+++S+ + + SL+ L N I S+ E
Sbjct: 374 AIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQT 433
Query: 178 NLMRIGLSFNKI 189
+L + L+ + +
Sbjct: 434 HLKELILNTSSL 445
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 88.6 bits (210), Expect = 5e-17
Identities = 72/278 (25%), Positives = 134/278 (48%), Gaps = 7/278 (2%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ SL N +PE+ LQ P +++LDL N I+++ F +Q L++L +++N+I+
Sbjct: 130 ITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRIT 188
Query: 76 EIEK---DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
+E D L L V L N+++ + + L L+++ + N +K +E
Sbjct: 189 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 248
Query: 133 MQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIE 190
++ + N + L + +++ L NN+ +++ L R L ++ +S N IE
Sbjct: 249 LRSLKMQRNGISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIE 308
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRR 249
++ D + ++L+ELD++YN+L L+ S L L LNL N +T + + L
Sbjct: 309 RISPDAWEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSN 368
Query: 250 LSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
L +DL +N+IS T + +L L N I
Sbjct: 369 LQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQI 406
Score = 62.1 bits (144), Expect = 5e-09
Identities = 78/336 (23%), Positives = 133/336 (39%), Gaps = 15/336 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
LP + N+L+ N +L L+ + +N N L I + L+ HN
Sbjct: 81 LPPDTAILDFSHNRLSNWNISLES-QTLQEVKMNYNELTEIPY-FGEPTSNITLLSLVHN 138
Query: 142 ELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE- 199
+ + + L+ P+L+SL N I + + L + LS N+I L F
Sbjct: 139 IIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRITTLEAGCFDNL 198
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+ L + + N + + + L L++L L N + +GL L + + N
Sbjct: 199 SSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNG 258
Query: 260 ISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXX-XXXXXXXXXXXXXXXXIQKIXXXX 317
IS L G+ L ++E EL L+HN++ I++I
Sbjct: 259 ISKLKDGAFFGLNNME----ELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDA 314
Query: 318 XXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADL 376
+SYN +T L+E++ L LE L N +T + D F L +L + DL
Sbjct: 315 WEFCQRLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 374
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
N+I + + G+ S+ K+ LQ N +
Sbjct: 375 RNNEISWA----IEDASEAFAGLTSLTKLILQGNQI 406
Score = 60.9 bits (141), Expect = 1e-08
Identities = 92/420 (21%), Positives = 172/420 (40%), Gaps = 28/420 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG----LKHVHLGI 93
P LD N+++ + Q L+ + + N+++EI P L VH I
Sbjct: 83 PDTAILDFSHNRLSNWNIS--LESQTLQEVKMNYNELTEIPYFGEPTSNITLLSLVHNII 140
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--K 151
++N AL+ LE + +++N + I+ + + ++ ++ ++N + +L +
Sbjct: 141 PEINAQ--ALQFYPALESLDLSSNIISEIKTSSFPRMQ-LKYLNLSNNRITTLEAGCFDN 197
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L SL + N + + + K +L + L N+I+ + F + L L + N
Sbjct: 198 LSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRN 257
Query: 212 ELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L +G+ L ++ L L HN +T + + GLR L + +S N I ++
Sbjct: 258 GISKLKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEF 317
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX-IQKIXXXXXXXXXXXXXXXV 329
R+ EL L +N + + I +
Sbjct: 318 CQ---RLSELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDL 374
Query: 330 SYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N I+ +E+ S+ F L SL +LI N I ++ K F GL SL DL+ N I ++
Sbjct: 375 RNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQ 434
Query: 386 YDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQTTA 445
+ S++ + ++ L + +LCD HL L+ N + S +C P+ A
Sbjct: 435 ENAFSQTH--------LKELILNTSSLLCDCHLKWLLQWLVDNNFQHSVNVSCAHPEWLA 486
Score = 50.4 bits (115), Expect = 2e-05
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTE---EDFRDI 61
L ES F L L++ +L DN + + V + L +++TLDL N+I+ E E F +
Sbjct: 334 LDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGL 393
Query: 62 QELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
L L++ NQI I K A + L+H+ L N + ++ L+ + +N ++L
Sbjct: 394 TSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELILNTSSL 453
Score = 47.2 bits (107), Expect = 2e-04
Identities = 47/228 (20%), Positives = 99/228 (43%), Gaps = 8/228 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + + L N + + Q L +++L + RN I+KL + F + +E L +
Sbjct: 221 KLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLNNMEELELEH 280
Query: 72 NQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N ++ + K L + L+ +++ N + ++ A L + ++ N L ++
Sbjct: 281 NNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQLTRLDESAFV 340
Query: 129 KAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNI----KSLDETLQKSRNLMRIG 183
++ ++ N + + + + + +LQ+L N I + E +L ++
Sbjct: 341 GLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLI 400
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL 231
L N+I+ +TK F E L LD+ N + + + S L+ L L
Sbjct: 401 LQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQTHLKELIL 448
Score = 42.7 bits (96), Expect = 0.003
Identities = 42/192 (21%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK+ F L+ ++ L N+L + + L L ++ L + +N I +++ + + Q L
Sbjct: 262 LKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRL 321
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLK- 120
L ++ NQ++ +++ A L+ ++LG N++ + +G R L +L+ + + N +
Sbjct: 322 SELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISW 381
Query: 121 SIENELPTKAKKMQL--IHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKSR 177
+IE+ A L + N+++S+ + + SL+ L N I S+ E
Sbjct: 382 AIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLNNNAIMSIQENAFSQT 441
Query: 178 NLMRIGLSFNKI 189
+L + L+ + +
Sbjct: 442 HLKELILNTSSL 453
>Z24680-1|CAA80847.1| 662|Homo sapiens garp protein.
Length = 662
Score = 88.2 bits (209), Expect = 7e-17
Identities = 76/276 (27%), Positives = 129/276 (46%), Gaps = 13/276 (4%)
Query: 13 LDLVDYFSLADNSLPE-LPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
L V L+ NSL L +L P + TL L N +T+LT FRD+ LE L +
Sbjct: 123 LPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHS 182
Query: 72 NQISEIEKDA---LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPT 128
N + +IE A LP+ L H++L N L ++ L L + ++ N++++ +
Sbjct: 183 NVLMDIEDGAFEGLPR-LTHLNLSRNSLTCISDF--SLQQLRVLDLSCNSIEAFQTASQP 239
Query: 129 KAK-KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+A+ ++ + N+L P DL +P L L N I+ Q S+ + ++
Sbjct: 240 QAEFQLTWLDLRENKLLHFP-DLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWS 298
Query: 188 KIEFLTKDDFTEAEKLAE---LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQE 243
+ L++ LD++YNE++ + S L L SL +LNL+ N + F +
Sbjct: 299 ALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARR 358
Query: 244 IKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE 279
+ L L ++DLSHN + L L + T +L+
Sbjct: 359 LGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQ 394
Score = 57.2 bits (132), Expect = 1e-07
Identities = 61/239 (25%), Positives = 110/239 (46%), Gaps = 16/239 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINK 95
P +TLDL N++ + L HL ++ N+IS ++ A L+H+ L N+
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 96 LNTLN----GALRDLDDLEWIFINANNLKS-IENELPTKAKKMQLIHAAHNELQSLP-SD 149
L G L L + + ++ N+L S + L +A + + A N L L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 150 LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ MP+L+ L + N + + D + L + LS N + ++ DF+ ++L LD+
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCIS--DFS-LQQLRVLDL 225
Query: 209 AYNELKYLNGSLRSLK--SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
+ N ++ + + L +L+L N + F ++ L RL ++LS+N I L TG
Sbjct: 226 SCNSIEAFQTASQPQAEFQLTWLDLRENKLLHF--PDLAALPRLIYLNLSNNLIRLPTG 282
Score = 53.6 bits (123), Expect = 2e-06
Identities = 54/211 (25%), Positives = 99/211 (46%), Gaps = 17/211 (8%)
Query: 82 LPKGLKHVHLGINKLNT-LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
LP + + L N+L + L L L + ++ N + ++ ++ + AH
Sbjct: 47 LPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAH 106
Query: 141 NELQSLPS----DLKLMPSLQSLYFYGNNIKS--LDETLQKSRNLMRIGLSFNKIEFLTK 194
N L + L +P + SL GN++ S L+ L ++ +L + L+ N + LT+
Sbjct: 107 NRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTR 166
Query: 195 DDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIKGLRRL 250
F + L +LD+ N L + +G+ L L +LNL+ N +T +FSLQ+++
Sbjct: 167 HTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLR----- 221
Query: 251 SVIDLSHNQISLLTGSLENLVDVETRVLELR 281
V+DLS N I + + + + L+LR
Sbjct: 222 -VLDLSCNSIEAFQTASQPQAEFQLTWLDLR 251
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 19/268 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L F + ++ L N L ++ + LP + L+L RN +T ++ DF +Q+L
Sbjct: 164 LTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCIS--DF-SLQQL 220
Query: 65 EHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDL-EWIFIN-ANNLKS 121
L ++ N I + + P+ + L + + L+ DL L I++N +NNL
Sbjct: 221 RVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLH--FPDLAALPRLIYLNLSNNLIR 278
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-------SDLKLMPSLQSLYFYGNNIKSL-DETL 173
+ P +K IHA +LP + + + L +L N I+ + D L
Sbjct: 279 LPTGPPQDSKG---IHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFL 335
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ +L + LS N + L LD+++N L+ L R+L SLR L L
Sbjct: 336 EHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQG 395
Query: 234 NYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
N + + L L ++L N++S
Sbjct: 396 NALRDLPPYTFANLASLQRLNLQGNRVS 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 13/212 (6%)
Query: 86 LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L ++ L N++ + + L L L ++ ++ N L++ E + L+ +HN L+
Sbjct: 317 LLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALE 376
Query: 145 SLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD------- 196
+L + + SL++L GN ++ L T +L R+ L N++ D
Sbjct: 377 TLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGC 436
Query: 197 --FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLSVI 253
F+ L L + NE++ L L L+L+ N E + + GL L V+
Sbjct: 437 VAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVL 496
Query: 254 DLSHNQISLLTGSLENLVDVE-TRVLELRLDH 284
L N + +L L + ++ + E RL H
Sbjct: 497 ALQGNGLMVLQVDLPCFICLKRLNLAENRLSH 528
Score = 36.3 bits (80), Expect = 0.29
Identities = 64/258 (24%), Positives = 95/258 (36%), Gaps = 15/258 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGIN 94
L + LDL N+I + + + L L ++ N + E L L + L N
Sbjct: 314 LSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHN 373
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSL-------P 147
L TL R L L + + N L+ + +Q ++ N + P
Sbjct: 374 ALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGP 433
Query: 148 SDLKL---MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK-IEFLTKDDFTEAEKL 203
S + SL+SL N I+ L L + LS N +E T L
Sbjct: 434 SGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASL 493
Query: 204 AELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
L + N L L L L+ LNL N ++ L L V+DL +N SLL
Sbjct: 494 EVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSH--LPAWTQAVSLEVLDLRNNSFSLL 551
Query: 264 TGSLENLVDVETRVLELR 281
GS ++ R L L+
Sbjct: 552 PGSAMGGLETSLRRLYLQ 569
Score = 35.5 bits (78), Expect = 0.50
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 5/179 (2%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
LD++ N+L+ + S L +LR+L+L+ N ++ + L L + L+HN++++ T
Sbjct: 54 LDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 113
Query: 265 GSLENLVDVETRVLELRLDHNHIFX--XXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
+ RV L L N ++ + ++
Sbjct: 114 ALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKI 381
+ N + +E+ + LP L L N++T + DF L L DLS N I
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI-SDF-SLQQLRVLDLSCNSI 230
>BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein.
Length = 662
Score = 88.2 bits (209), Expect = 7e-17
Identities = 76/276 (27%), Positives = 129/276 (46%), Gaps = 13/276 (4%)
Query: 13 LDLVDYFSLADNSLPE-LPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
L V L+ NSL L +L P + TL L N +T+LT FRD+ LE L +
Sbjct: 123 LPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHS 182
Query: 72 NQISEIEKDA---LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPT 128
N + +IE A LP+ L H++L N L ++ L L + ++ N++++ +
Sbjct: 183 NVLMDIEDGAFEGLPR-LTHLNLSRNSLTCISDF--SLQQLRVLDLSCNSIEAFQTASQP 239
Query: 129 KAK-KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+A+ ++ + N+L P DL +P L L N I+ Q S+ + ++
Sbjct: 240 QAEFQLTWLDLRENKLLHFP-DLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWS 298
Query: 188 KIEFLTKDDFTEAEKLAE---LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQE 243
+ L++ LD++YNE++ + S L L SL +LNL+ N + F +
Sbjct: 299 ALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARR 358
Query: 244 IKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE 279
+ L L ++DLSHN + L L + T +L+
Sbjct: 359 LGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQ 394
Score = 57.2 bits (132), Expect = 1e-07
Identities = 61/239 (25%), Positives = 110/239 (46%), Gaps = 16/239 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINK 95
P +TLDL N++ + L HL ++ N+IS ++ A L+H+ L N+
Sbjct: 49 PDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNR 108
Query: 96 LNTLN----GALRDLDDLEWIFINANNLKS-IENELPTKAKKMQLIHAAHNELQSLP-SD 149
L G L L + + ++ N+L S + L +A + + A N L L
Sbjct: 109 LAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHT 168
Query: 150 LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ MP+L+ L + N + + D + L + LS N + ++ DF+ ++L LD+
Sbjct: 169 FRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCIS--DFS-LQQLRVLDL 225
Query: 209 AYNELKYLNGSLRSLK--SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
+ N ++ + + L +L+L N + F ++ L RL ++LS+N I L TG
Sbjct: 226 SCNSIEAFQTASQPQAEFQLTWLDLRENKLLHF--PDLAALPRLIYLNLSNNLIRLPTG 282
Score = 53.6 bits (123), Expect = 2e-06
Identities = 54/211 (25%), Positives = 99/211 (46%), Gaps = 17/211 (8%)
Query: 82 LPKGLKHVHLGINKLNT-LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
LP + + L N+L + L L L + ++ N + ++ ++ + AH
Sbjct: 47 LPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAH 106
Query: 141 NELQSLPS----DLKLMPSLQSLYFYGNNIKS--LDETLQKSRNLMRIGLSFNKIEFLTK 194
N L + L +P + SL GN++ S L+ L ++ +L + L+ N + LT+
Sbjct: 107 NRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTR 166
Query: 195 DDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIKGLRRL 250
F + L +LD+ N L + +G+ L L +LNL+ N +T +FSLQ+++
Sbjct: 167 HTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLR----- 221
Query: 251 SVIDLSHNQISLLTGSLENLVDVETRVLELR 281
V+DLS N I + + + + L+LR
Sbjct: 222 -VLDLSCNSIEAFQTASQPQAEFQLTWLDLR 251
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 19/268 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L F + ++ L N L ++ + LP + L+L RN +T ++ DF +Q+L
Sbjct: 164 LTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCIS--DF-SLQQL 220
Query: 65 EHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDL-EWIFIN-ANNLKS 121
L ++ N I + + P+ + L + + L+ DL L I++N +NNL
Sbjct: 221 RVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLH--FPDLAALPRLIYLNLSNNLIR 278
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-------SDLKLMPSLQSLYFYGNNIKSL-DETL 173
+ P +K IHA +LP + + + L +L N I+ + D L
Sbjct: 279 LPTGPPQDSKG---IHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFL 335
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ +L + LS N + L LD+++N L+ L R+L SLR L L
Sbjct: 336 EHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQG 395
Query: 234 NYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
N + + L L ++L N++S
Sbjct: 396 NALRDLPPYTFANLASLQRLNLQGNRVS 423
Score = 44.0 bits (99), Expect = 0.001
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 13/212 (6%)
Query: 86 LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L ++ L N++ + + L L L ++ ++ N L++ E + L+ +HN L+
Sbjct: 317 LLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALE 376
Query: 145 SLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD------- 196
+L + + SL++L GN ++ L T +L R+ L N++ D
Sbjct: 377 TLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGC 436
Query: 197 --FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLSVI 253
F+ L L + NE++ L L L+L+ N E + + GL L V+
Sbjct: 437 VAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVL 496
Query: 254 DLSHNQISLLTGSLENLVDVE-TRVLELRLDH 284
L N + +L L + ++ + E RL H
Sbjct: 497 ALQGNGLMVLQVDLPCFICLKRLNLAENRLSH 528
Score = 36.3 bits (80), Expect = 0.29
Identities = 64/258 (24%), Positives = 95/258 (36%), Gaps = 15/258 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGIN 94
L + LDL N+I + + + L L ++ N + E L L + L N
Sbjct: 314 LSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHN 373
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSL-------P 147
L TL R L L + + N L+ + +Q ++ N + P
Sbjct: 374 ALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGP 433
Query: 148 SDLKL---MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK-IEFLTKDDFTEAEKL 203
S + SL+SL N I+ L L + LS N +E T L
Sbjct: 434 SGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASL 493
Query: 204 AELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
L + N L L L L+ LNL N ++ L L V+DL +N SLL
Sbjct: 494 EVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSH--LPAWTQAVSLEVLDLRNNSFSLL 551
Query: 264 TGSLENLVDVETRVLELR 281
GS ++ R L L+
Sbjct: 552 PGSAMGGLETSLRRLYLQ 569
Score = 35.5 bits (78), Expect = 0.50
Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 5/179 (2%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
LD++ N+L+ + S L +LR+L+L+ N ++ + L L + L+HN++++ T
Sbjct: 54 LDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 113
Query: 265 GSLENLVDVETRVLELRLDHNHIFX--XXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
+ RV L L N ++ + ++
Sbjct: 114 ALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP 173
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKI 381
+ N + +E+ + LP L L N++T + DF L L DLS N I
Sbjct: 174 ALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI-SDF-SLQQLRVLDLSCNSI 230
>BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein.
Length = 552
Score = 88.2 bits (209), Expect = 7e-17
Identities = 76/276 (27%), Positives = 129/276 (46%), Gaps = 13/276 (4%)
Query: 13 LDLVDYFSLADNSLPE-LPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
L V L+ NSL L +L P + TL L N +T+LT FRD+ LE L +
Sbjct: 13 LPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHS 72
Query: 72 NQISEIEKDA---LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPT 128
N + +IE A LP+ L H++L N L ++ L L + ++ N++++ +
Sbjct: 73 NVLMDIEDGAFEGLPR-LTHLNLSRNSLTCISDF--SLQQLRVLDLSCNSIEAFQTASQP 129
Query: 129 KAK-KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+A+ ++ + N+L P DL +P L L N I+ Q S+ + ++
Sbjct: 130 QAEFQLTWLDLRENKLLHFP-DLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWS 188
Query: 188 KIEFLTKDDFTEAEKLAE---LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQE 243
+ L++ LD++YNE++ + S L L SL +LNL+ N + F +
Sbjct: 189 ALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARR 248
Query: 244 IKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE 279
+ L L ++DLSHN + L L + T +L+
Sbjct: 249 LGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQ 284
Score = 51.6 bits (118), Expect = 7e-06
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 12/135 (8%)
Query: 153 MPSLQSLYFYGNNIKS--LDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+P + SL GN++ S L+ L ++ +L + L+ N + LT+ F + L +LD+
Sbjct: 13 LPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHS 72
Query: 211 NELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
N L + +G+ L L +LNL+ N +T +FSLQ+++ V+DLS N I +
Sbjct: 73 NVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLR------VLDLSCNSIEAFQTA 126
Query: 267 LENLVDVETRVLELR 281
+ + + L+LR
Sbjct: 127 SQPQAEFQLTWLDLR 141
Score = 47.2 bits (107), Expect = 2e-04
Identities = 66/268 (24%), Positives = 115/268 (42%), Gaps = 19/268 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L F + ++ L N L ++ + LP + L+L RN +T ++ DF +Q+L
Sbjct: 54 LTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCIS--DF-SLQQL 110
Query: 65 EHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDL-EWIFIN-ANNLKS 121
L ++ N I + + P+ + L + + L+ DL L I++N +NNL
Sbjct: 111 RVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLH--FPDLAALPRLIYLNLSNNLIR 168
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-------SDLKLMPSLQSLYFYGNNIKSL-DETL 173
+ P +K IHA +LP + + + L +L N I+ + D L
Sbjct: 169 LPTGPPQDSKG---IHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFL 225
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ +L + LS N + L LD+++N L+ L R+L SLR L L
Sbjct: 226 EHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQG 285
Query: 234 NYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
N + + L L ++L N++S
Sbjct: 286 NALRDLPPYTFANLASLQRLNLQGNRVS 313
Score = 44.0 bits (99), Expect = 0.001
Identities = 49/212 (23%), Positives = 91/212 (42%), Gaps = 13/212 (6%)
Query: 86 LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L ++ L N++ + + L L L ++ ++ N L++ E + L+ +HN L+
Sbjct: 207 LLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALE 266
Query: 145 SLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD------- 196
+L + + SL++L GN ++ L T +L R+ L N++ D
Sbjct: 267 TLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGC 326
Query: 197 --FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLSVI 253
F+ L L + NE++ L L L+L+ N E + + GL L V+
Sbjct: 327 VAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVL 386
Query: 254 DLSHNQISLLTGSLENLVDVE-TRVLELRLDH 284
L N + +L L + ++ + E RL H
Sbjct: 387 ALQGNGLMVLQVDLPCFICLKRLNLAENRLSH 418
Score = 36.3 bits (80), Expect = 0.29
Identities = 64/258 (24%), Positives = 95/258 (36%), Gaps = 15/258 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGIN 94
L + LDL N+I + + + L L ++ N + E L L + L N
Sbjct: 204 LSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHN 263
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSL-------P 147
L TL R L L + + N L+ + +Q ++ N + P
Sbjct: 264 ALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGP 323
Query: 148 SDLKL---MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK-IEFLTKDDFTEAEKL 203
S + SL+SL N I+ L L + LS N +E T L
Sbjct: 324 SGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASL 383
Query: 204 AELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
L + N L L L L+ LNL N ++ L L V+DL +N SLL
Sbjct: 384 EVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSH--LPAWTQAVSLEVLDLRNNSFSLL 441
Query: 264 TGSLENLVDVETRVLELR 281
GS ++ R L L+
Sbjct: 442 PGSAMGGLETSLRRLYLQ 459
>M14219-1|AAB00774.1| 359|Homo sapiens proteoglycan core protein
protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>CR541946-1|CAG46744.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>CR407676-1|CAG28604.1| 359|Homo sapiens DCN protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>BT019800-1|AAV38603.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>BC005322-1|AAH05322.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>AF491944-1|AAL92176.1| 359|Homo sapiens decorin protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>AF138300-1|AAD44713.1| 359|Homo sapiens decorin variant A protein.
Length = 359
Score = 87.0 bits (206), Expect = 2e-16
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 7/218 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L EL + N+L + G L K ++ + L +N
Sbjct: 265 LANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNN 302
Score = 50.4 bits (115), Expect = 2e-05
Identities = 42/181 (23%), Positives = 86/181 (47%), Gaps = 25/181 (13%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLT--------------- 54
FT L ++ L+ N L ELP + + L ++ + K+ K+T
Sbjct: 125 FTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTN 184
Query: 55 --------EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRD 105
F+ +++L ++ +AD I+ I + LP L +HL NK++ ++ A L+
Sbjct: 185 PLKSSGIENGAFQGMKKLSYIRIADTNITSIPQ-GLPPSLTELHLDGNKISRVDAASLKG 243
Query: 106 LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNN 165
L++L + ++ N++ +++N ++ +H +N+L +P L +Q +Y + NN
Sbjct: 244 LNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNN 303
Query: 166 I 166
I
Sbjct: 304 I 304
>AL159161-1|CAI17102.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 86.2 bits (204), Expect = 3e-16
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKL 96
+V L L +NKI L ++ F +L+ + + N I I + A L+ ++L N +
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMP 154
TL G +DL L W+ ++ N + I L T + + +N L++LP + MP
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 155 SLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L + GN IK L + T +L + L N+I F+ + F+ + L ELD++ N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 214 KYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L+ L + LK L+ LNL+ N + + + L++L +DL +I
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 365
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 13/242 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + VF K + L N + + R L +++ L L N IT L F+D+ +L
Sbjct: 152 LPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQL 211
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGAL-----RDLDDLEWIFINANNL 119
L++ DN I+ I + L GL + ++ +N AL + L W+ + N +
Sbjct: 212 TWLILDDNPITRISQ-RLFTGLNSLFF-LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRI 269
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
K + N + ++ N++ +P + +L L N I L L K
Sbjct: 270 KYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLK 329
Query: 179 LM-RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
L+ ++ LS N + +L K+ F ++L LD+ E+ +N R + ++ NL+H Y
Sbjct: 330 LLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNIN--TRMFQPMK--NLSHIYFK 385
Query: 238 EF 239
F
Sbjct: 386 NF 387
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLM-PSLQSLYFYGNNIKSLD-ETLQKSRNLMRIG 183
+P + + L+ N++ SLP + + L+ ++ N I+ + + NL +
Sbjct: 132 VPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILY 191
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
L+ N I L F + +L L + N + ++ L L SL +L++ +NY+ Q
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 243 EIKGLRRLSVIDLSHNQISLLTGS 266
+ +L+ +DL N+I LT S
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNS 275
>AL138708-1|CAH73785.1| 754|Homo sapiens relaxin/insulin-like
family peptide receptor 2 protein.
Length = 754
Score = 86.2 bits (204), Expect = 3e-16
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKL 96
+V L L +NKI L ++ F +L+ + + N I I + A L+ ++L N +
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMP 154
TL G +DL L W+ ++ N + I L T + + +N L++LP + MP
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 155 SLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L + GN IK L + T +L + L N+I F+ + F+ + L ELD++ N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 214 KYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L+ L + LK L+ LNL+ N + + + L++L +DL +I
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 365
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 13/242 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + VF K + L N + + R L +++ L L N IT L F+D+ +L
Sbjct: 152 LPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQL 211
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGAL-----RDLDDLEWIFINANNL 119
L++ DN I+ I + L GL + ++ +N AL + L W+ + N +
Sbjct: 212 TWLILDDNPITRISQ-RLFTGLNSLFF-LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRI 269
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
K + N + ++ N++ +P + +L L N I L L K
Sbjct: 270 KYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLK 329
Query: 179 LM-RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
L+ ++ LS N + +L K+ F ++L LD+ E+ +N R + ++ NL+H Y
Sbjct: 330 LLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNIN--TRMFQPMK--NLSHIYFK 385
Query: 238 EF 239
F
Sbjct: 386 NF 387
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLM-PSLQSLYFYGNNIKSLD-ETLQKSRNLMRIG 183
+P + + L+ N++ SLP + + L+ ++ N I+ + + NL +
Sbjct: 132 VPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILY 191
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
L+ N I L F + +L L + N + ++ L L SL +L++ +NY+ Q
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 243 EIKGLRRLSVIDLSHNQISLLTGS 266
+ +L+ +DL N+I LT S
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNS 275
>AF453828-1|AAL73946.1| 754|Homo sapiens G protein-coupled receptor
affecting testicular descent protein.
Length = 754
Score = 86.2 bits (204), Expect = 3e-16
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKL 96
+V L L +NKI L ++ F +L+ + + N I I + A L+ ++L N +
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMP 154
TL G +DL L W+ ++ N + I L T + + +N L++LP + MP
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 155 SLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L + GN IK L + T +L + L N+I F+ + F+ + L ELD++ N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 214 KYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L+ L + LK L+ LNL+ N + + + L++L +DL +I
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 365
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 13/242 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + VF K + L N + + R L +++ L L N IT L F+D+ +L
Sbjct: 152 LPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQL 211
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGAL-----RDLDDLEWIFINANNL 119
L++ DN I+ I + L GL + ++ +N AL + L W+ + N +
Sbjct: 212 TWLILDDNPITRISQ-RLFTGLNSLFF-LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRI 269
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
K + N + ++ N++ +P + +L L N I L L K
Sbjct: 270 KYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLK 329
Query: 179 LM-RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
L+ ++ LS N + +L K+ F ++L LD+ E+ +N R + ++ NL+H Y
Sbjct: 330 LLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNIN--TRMFQPMK--NLSHIYFK 385
Query: 238 EF 239
F
Sbjct: 386 NF 387
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLM-PSLQSLYFYGNNIKSLD-ETLQKSRNLMRIG 183
+P + + L+ N++ SLP + + L+ ++ N I+ + + NL +
Sbjct: 132 VPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILY 191
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
L+ N I L F + +L L + N + ++ L L SL +L++ +NY+ Q
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 243 EIKGLRRLSVIDLSHNQISLLTGS 266
+ +L+ +DL N+I LT S
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNS 275
>AF403384-1|AAL69324.2| 754|Homo sapiens LGR8 protein.
Length = 754
Score = 86.2 bits (204), Expect = 3e-16
Identities = 65/228 (28%), Positives = 112/228 (49%), Gaps = 6/228 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKL 96
+V L L +NKI L ++ F +L+ + + N I I + A L+ ++L N +
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMP 154
TL G +DL L W+ ++ N + I L T + + +N L++LP + MP
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 155 SLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L + GN IK L + T +L + L N+I F+ + F+ + L ELD++ N +
Sbjct: 258 QLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTI 317
Query: 214 KYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L+ L + LK L+ LNL+ N + + + L++L +DL +I
Sbjct: 318 TELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 365
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/242 (24%), Positives = 106/242 (43%), Gaps = 13/242 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + VF K + L N + + R L +++ L L N IT L F+D+ +L
Sbjct: 152 LPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQL 211
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGAL-----RDLDDLEWIFINANNL 119
L++ DN I+ I + L GL + ++ +N AL + L W+ + N +
Sbjct: 212 TWLILDDNPITRISQ-RLFTGLNSLFF-LSMVNNYLEALPKQMCAQMPQLNWVDLEGNRI 269
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
K + N + ++ N++ +P + +L L N I L L K
Sbjct: 270 KYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLK 329
Query: 179 LM-RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT 237
L+ ++ LS N + +L K+ F ++L LD+ E+ +N R + ++ NL+H Y
Sbjct: 330 LLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNIN--TRMFQPMK--NLSHIYFK 385
Query: 238 EF 239
F
Sbjct: 386 NF 387
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLM-PSLQSLYFYGNNIKSLD-ETLQKSRNLMRIG 183
+P + + L+ N++ SLP + + L+ ++ N I+ + + NL +
Sbjct: 132 VPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILY 191
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
L+ N I L F + +L L + N + ++ L L SL +L++ +NY+ Q
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 243 EIKGLRRLSVIDLSHNQISLLTGS 266
+ +L+ +DL N+I LT S
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNS 275
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 85.4 bits (202), Expect = 5e-16
Identities = 67/239 (28%), Positives = 115/239 (48%), Gaps = 6/239 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E +F L ++ L N L LPR + Q L H+KTL+L +N + +L EE F + L
Sbjct: 136 LPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSL 195
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +++N +S + + K L+ + L N ++ L L LE +++ N +
Sbjct: 196 QTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITH 255
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDE-TLQKSRNL 179
+ + + + N L+ LP+ L P L L N ++++ E T NL
Sbjct: 256 LPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNL 315
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMT 237
+ LS+N I L F + E+L +L + N L L+ +L ++L L L+L+ N +T
Sbjct: 316 RSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLT 374
Score = 84.2 bits (199), Expect = 1e-15
Identities = 72/289 (24%), Positives = 137/289 (47%), Gaps = 13/289 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ++F+ L + +L N L LP + QHL +++L L N++ L F+ + L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +A N ++++ ++ L+ + L N L+ L G L L+ +F+++NN+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYG---NNIKSLDETL-QKSR 177
+ ++ ++ ++ + N + LP L + SL +L F N ++ L L +
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLP--LSIFASLGNLTFLSLQWNMLRVLPAGLFAHTP 289
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYM 236
L+ + L+ N++E + + F L L ++YN + +L G R L+ L L L N +
Sbjct: 290 CLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
T + L +L ++ LS NQ++ L E + D + L L N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLP---EGIFDTNYNLFNLALHGN 395
Score = 58.0 bits (134), Expect = 8e-08
Identities = 98/426 (23%), Positives = 160/426 (37%), Gaps = 43/426 (10%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA---LPKGLKHVHL-GI 93
P+ K + T L F L ++ + Q+ + DA LP+ L+ + + G
Sbjct: 49 PYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPR-LEDLEVTGS 107
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KL 152
+ LN +L L + +N N L+++ L ++ +H N+LQ+LP L +
Sbjct: 108 SFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQP 167
Query: 153 MPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L++L N + L E L +L + LS N + L + F + L EL + N
Sbjct: 168 LTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSN 227
Query: 212 ELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L + S L L L L N +T L L L+ + L N + +L L
Sbjct: 228 NISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAG---L 284
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVS 330
++ L L HN + + + +S
Sbjct: 285 FAHTPCLVGLSLTHNQL-----------------------ETVAEGTFAHLSNLRSLMLS 321
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKIHTVNYDLV 389
YN IT L L L +L NN+T L F L L LS N++ T+ +
Sbjct: 322 YNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIF 381
Query: 390 SKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGAST-CVAPQTTAPIL 448
+ ++ + L NP CD HL L + R+ T C P +
Sbjct: 382 DTNY-------NLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQV 434
Query: 449 MRALND 454
+ ALN+
Sbjct: 435 VPALNE 440
Score = 39.9 bits (89), Expect = 0.023
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL +F + SL N L + HL ++++L L N IT L FRD++E
Sbjct: 279 VLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEE 338
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRD 105
L L + N ++ + L+ + L N+L TL + D
Sbjct: 339 LVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFD 382
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 85.4 bits (202), Expect = 5e-16
Identities = 67/239 (28%), Positives = 115/239 (48%), Gaps = 6/239 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E +F L ++ L N L LPR + Q L H+KTL+L +N + +L EE F + L
Sbjct: 136 LPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSL 195
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +++N +S + + K L+ + L N ++ L L LE +++ N +
Sbjct: 196 QTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITH 255
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDE-TLQKSRNL 179
+ + + + N L+ LP+ L P L L N ++++ E T NL
Sbjct: 256 LPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNL 315
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMT 237
+ LS+N I L F + E+L +L + N L L+ +L ++L L L+L+ N +T
Sbjct: 316 RSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLT 374
Score = 84.2 bits (199), Expect = 1e-15
Identities = 72/289 (24%), Positives = 137/289 (47%), Gaps = 13/289 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ++F+ L + +L N L LP + QHL +++L L N++ L F+ + L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQPLTHL 171
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +A N ++++ ++ L+ + L N L+ L G L L+ +F+++NN+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYG---NNIKSLDETL-QKSR 177
+ ++ ++ ++ + N + LP L + SL +L F N ++ L L +
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLP--LSIFASLGNLTFLSLQWNMLRVLPAGLFAHTP 289
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYM 236
L+ + L+ N++E + + F L L ++YN + +L G R L+ L L L N +
Sbjct: 290 CLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
T + L +L ++ LS NQ++ L E + D + L L N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLP---EGIFDTNYNLFNLALHGN 395
Score = 58.0 bits (134), Expect = 8e-08
Identities = 98/426 (23%), Positives = 160/426 (37%), Gaps = 43/426 (10%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA---LPKGLKHVHL-GI 93
P+ K + T L F L ++ + Q+ + DA LP+ L+ + + G
Sbjct: 49 PYTKNIIFVETSFTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPR-LEDLEVTGS 107
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KL 152
+ LN +L L + +N N L+++ L ++ +H N+LQ+LP L +
Sbjct: 108 SFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNQLQALPRRLFQP 167
Query: 153 MPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L++L N + L E L +L + LS N + L + F + L EL + N
Sbjct: 168 LTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSN 227
Query: 212 ELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
+ L + S L L L L N +T L L L+ + L N + +L L
Sbjct: 228 NISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFLSLQWNMLRVLPAG---L 284
Query: 271 VDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVS 330
++ L L HN + + + +S
Sbjct: 285 FAHTPCLVGLSLTHNQL-----------------------ETVAEGTFAHLSNLRSLMLS 321
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKIHTVNYDLV 389
YN IT L L L +L NN+T L F L L LS N++ T+ +
Sbjct: 322 YNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIF 381
Query: 390 SKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGAST-CVAPQTTAPIL 448
+ ++ + L NP CD HL L + R+ T C P +
Sbjct: 382 DTNY-------NLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQV 434
Query: 449 MRALND 454
+ ALN+
Sbjct: 435 VPALNE 440
Score = 39.9 bits (89), Expect = 0.023
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL +F + SL N L + HL ++++L L N IT L FRD++E
Sbjct: 279 VLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEE 338
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRD 105
L L + N ++ + L+ + L N+L TL + D
Sbjct: 339 LVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFD 382
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 85.0 bits (201), Expect = 6e-16
Identities = 67/239 (28%), Positives = 115/239 (48%), Gaps = 6/239 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E +F L ++ L N L LPR + Q L H+KTL+L +N + +L EE F + L
Sbjct: 136 LPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSL 195
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +++N +S + + K L+ + L N ++ L L LE +++ N +
Sbjct: 196 QTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITH 255
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDE-TLQKSRNL 179
+ + + + N L+ LP+ L P L L N ++++ E T NL
Sbjct: 256 LPLSIFASLGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNL 315
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMT 237
+ LS+N I L F + E+L +L + N L L+ +L ++L L L+L+ N +T
Sbjct: 316 RSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLT 374
Score = 84.6 bits (200), Expect = 8e-16
Identities = 72/289 (24%), Positives = 137/289 (47%), Gaps = 13/289 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ++F+ L + +L N L LP + QHL +++L L N++ L F+ + L
Sbjct: 112 LSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGNRLQALPRRLFQPLTHL 171
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L +A N ++++ ++ L+ + L N L+ L G L L+ +F+++NN+
Sbjct: 172 KTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQGVFGKLGSLQELFLDSNNISE 231
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYG---NNIKSLDETL-QKSR 177
+ ++ ++ ++ + N + LP L + SL +L F N ++ L L +
Sbjct: 232 LPPQVFSQLFCLERLWLQRNAITHLP--LSIFASLGNLTFLSLQWNMLRVLPAGLFAHTP 289
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYM 236
L+ + L+ N++E + + F L L ++YN + +L G R L+ L L L N +
Sbjct: 290 CLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEELVKLYLGSNNL 349
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
T + L +L ++ LS NQ++ L E + D + L L N
Sbjct: 350 TALHPALFQNLSKLELLSLSKNQLTTLP---EGIFDTNYNLFNLALHGN 395
Score = 57.6 bits (133), Expect = 1e-07
Identities = 86/363 (23%), Positives = 142/363 (39%), Gaps = 25/363 (6%)
Query: 101 GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSL 159
G L L+DLE + ++ ++ + + + + N L++LP L + + +L+SL
Sbjct: 94 GGLPRLEDLE---VTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESL 150
Query: 160 YFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ GN +++L L Q +L + L+ N + L ++ F L L ++ N L L
Sbjct: 151 HLQGNRLQALPRRLFQPLTHLKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLPQ 210
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT----GSLENLVDV 273
G L SL+ L L N ++E Q L L + L N I+ L SL NL +
Sbjct: 211 GVFGKLGSLQELFLDSNNISELPPQVFSQLFCLERLWLQRNAITHLPLSIFASLGNLTFL 270
Query: 274 ETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNH 333
+ LR+ +F ++ + +SYN
Sbjct: 271 SLQWNMLRVLPAGLFAHTPCLVGLSLTHNQ------LETVAEGTFAHLSNLRSLMLSYNA 324
Query: 334 ITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKIHTVNYDLVSKS 392
IT L L L +L NN+T L F L L LS N++ T+ + +
Sbjct: 325 ITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTN 384
Query: 393 RCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGAST-CVAPQTTAPILMRA 451
++ + L NP CD HL L + R+ T C P ++ A
Sbjct: 385 Y-------NLFNLALHGNPWQCDCHLAYLFNWLQQYTDRLLNIQTYCAGPAYLKGQVVPA 437
Query: 452 LND 454
LN+
Sbjct: 438 LNE 440
Score = 39.9 bits (89), Expect = 0.023
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL +F + SL N L + HL ++++L L N IT L FRD++E
Sbjct: 279 VLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHLSNLRSLMLSYNAITHLPAGIFRDLEE 338
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRD 105
L L + N ++ + L+ + L N+L TL + D
Sbjct: 339 LVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFD 382
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 84.2 bits (199), Expect = 1e-15
Identities = 76/276 (27%), Positives = 124/276 (44%), Gaps = 7/276 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES F + + + N L + ++L ++ L L NK+ L F+ + L
Sbjct: 68 LNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSL 127
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
E LL++ NQ+ +I+ + LK + L N L + +GA L L + + N+L
Sbjct: 128 ESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTH 187
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNL 179
I + +Q++ N L +P + +LQ L N I L L + NL
Sbjct: 188 ISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNL 247
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
R+ LS N I L F + +L L + N LK L+ G + +LR L L N+++
Sbjct: 248 QRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISS 307
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDV 273
LR+L V+ LS NQIS ++ G+ L ++
Sbjct: 308 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTEL 343
Score = 77.8 bits (183), Expect = 9e-14
Identities = 77/284 (27%), Positives = 130/284 (45%), Gaps = 27/284 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + +L NSL + V QHL +++ L L N++T + F + L
Sbjct: 164 IPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNL 223
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
+ L + NQI L GL H + + +L N + L S+
Sbjct: 224 QELALQQNQIG-----LLSPGLFHNNHNLQRLYLSNNHISQLP------------PSVFM 266
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIG 183
+LP + ++ L + EL P MP+L+ L+ Y N+I SL D R L +
Sbjct: 267 QLP-QLNRLTLFGNSLKELS--PGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
LS N+I F++ F +L EL + N L+ L+G++ R L +L+ ++L +N + +
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 243 EIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHN 285
+ L I L +NQ+ +L G ++L ++ ELRL N
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHL----GKLCELRLYDN 423
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 84.2 bits (199), Expect = 1e-15
Identities = 76/276 (27%), Positives = 124/276 (44%), Gaps = 7/276 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES F + + + N L + ++L ++ L L NK+ L F+ + L
Sbjct: 68 LNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSL 127
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
E LL++ NQ+ +I+ + LK + L N L + +GA L L + + N+L
Sbjct: 128 ESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTH 187
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNL 179
I + +Q++ N L +P + +LQ L N I L L + NL
Sbjct: 188 ISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNL 247
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
R+ LS N I L F + +L L + N LK L+ G + +LR L L N+++
Sbjct: 248 QRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELSPGIFGPMPNLRELWLYDNHISS 307
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDV 273
LR+L V+ LS NQIS ++ G+ L ++
Sbjct: 308 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTEL 343
Score = 77.8 bits (183), Expect = 9e-14
Identities = 77/284 (27%), Positives = 130/284 (45%), Gaps = 27/284 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + +L NSL + V QHL +++ L L N++T + F + L
Sbjct: 164 IPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNL 223
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
+ L + NQI L GL H + + +L N + L S+
Sbjct: 224 QELALQQNQIG-----LLSPGLFHNNHNLQRLYLSNNHISQLP------------PSVFM 266
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIG 183
+LP + ++ L + EL P MP+L+ L+ Y N+I SL D R L +
Sbjct: 267 QLP-QLNRLTLFGNSLKELS--PGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
LS N+I F++ F +L EL + N L+ L+G++ R L +L+ ++L +N + +
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 243 EIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHN 285
+ L I L +NQ+ +L G ++L ++ ELRL N
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHL----GKLCELRLYDN 423
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 84.2 bits (199), Expect = 1e-15
Identities = 76/276 (27%), Positives = 124/276 (44%), Gaps = 7/276 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES F + + + N L + ++L ++ L L NK+ L F+ + L
Sbjct: 68 LNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSL 127
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
E LL++ NQ+ +I+ + LK + L N L + +GA L L + + N+L
Sbjct: 128 ESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTH 187
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNL 179
I + +Q++ N L +P + +LQ L N I L L + NL
Sbjct: 188 ISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNL 247
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTE 238
R+ LS N I L F + +L L + N LK L+ G + +LR L L N+++
Sbjct: 248 QRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISS 307
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDV 273
LR+L V+ LS NQIS ++ G+ L ++
Sbjct: 308 LPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTEL 343
Score = 74.9 bits (176), Expect = 7e-13
Identities = 79/284 (27%), Positives = 131/284 (46%), Gaps = 27/284 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + +L NSL + V QHL +++ L L N++T + F + L
Sbjct: 164 IPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNL 223
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
+ L + NQI L GL H + + +L N + L SI
Sbjct: 224 QELALQQNQIG-----LLSPGLFHNNHNLQRLYLSNNHISQLP------------PSIFM 266
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIG 183
+LP + ++ L + EL SL MP+L+ L+ Y N+I SL D R L +
Sbjct: 267 QLP-QLNRLTLFGNSLKEL-SL-GIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLI 323
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
LS N+I F++ F +L EL + N L+ L+G++ R L +L+ ++L +N + +
Sbjct: 324 LSRNQISFISPGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGN 383
Query: 243 EIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHN 285
+ L I L +NQ+ +L G ++L ++ ELRL N
Sbjct: 384 IFANVNGLMAIQLQNNQLENLPLGIFDHL----GKLCELRLYDN 423
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 83.0 bits (196), Expect = 3e-15
Identities = 77/282 (27%), Positives = 131/282 (46%), Gaps = 10/282 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +F +L + L+DN + LP V + V+ LD+ RN I ++ E + + LE
Sbjct: 23 QGLFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVE-LDVSRNDIPEIPES-IKFCKALEI 80
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
+ N +S + + L H+ L L L G + +L +L + + N LKS+
Sbjct: 81 ADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPAS 140
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L K QL N+L+ LP L +P+L+ L+ N + +L L R L+ + +S
Sbjct: 141 LSFLVKLEQL-DLGGNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVS 199
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L + L +L ++ N L+ L + LK L L + N + E + + I
Sbjct: 200 ENRLEELPA-ELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT-EAIG 257
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
LS + L+ N + L SL L T++ L +D NH+
Sbjct: 258 DCENLSELILTENLLMALPRSLGKL----TKLTNLNVDRNHL 295
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/245 (26%), Positives = 116/245 (47%), Gaps = 4/245 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ L
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRV 277
S+ +L L+ L L N ++E QEI L+ L +D+S N++ L + L + V
Sbjct: 191 ESIGALLHLKDLWLDGNQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLV 249
Query: 278 LELRL 282
+ L
Sbjct: 250 ISQNL 254
Score = 72.1 bits (169), Expect = 5e-12
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F +L + L+DN + LP + + V+ LD+ RN+I ++ E I + L V
Sbjct: 55 FFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPES----ISFCKALQV 109
Query: 70 ADNQISEIEK--DALPKGLKHVHLGIN--KLNTLNGALRDLDDLEWIFINANNLKSIENE 125
AD + + + ++ P+ L +N L +L + +L +L + + N L + +
Sbjct: 110 ADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDS 169
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L T+ ++++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S
Sbjct: 170 L-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVS 228
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L ++ + L +L I+ N L+ + + LK L L + N +T+ + +
Sbjct: 229 ENRLERL-PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP-EAVG 286
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L+ + L+ NQ+ L S+ L
Sbjct: 287 ECESLTELVLTENQLLTLPKSIGKL 311
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/240 (25%), Positives = 106/240 (44%), Gaps = 7/240 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N L LP + Q L ++ LDL N+I L E + L+ L + NQ+SE+ ++
Sbjct: 158 LRENLLTYLPDSLTQ-LRRLEELDLGNNEIYNLPES-IGALLHLKDLWLDGNQLSELPQE 215
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
K L + + N+L L + L L + I+ N L++I + + K KK+ ++
Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIG-KLKKLSILKVD 274
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N L LP + SL L N + +L +++ K + L + NK+ L K +
Sbjct: 275 QNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPK-EIGG 333
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L + N L + + L L++ N + L + L +L + LS NQ
Sbjct: 334 CCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL-SLTAL-KLKALWLSDNQ 391
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/245 (26%), Positives = 116/245 (47%), Gaps = 4/245 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ L
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRV 277
S+ +L L+ L L N ++E QEI L+ L +D+S N++ L + L + V
Sbjct: 191 ESIGALLHLKDLWLDGNQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLV 249
Query: 278 LELRL 282
+ L
Sbjct: 250 ISQNL 254
Score = 72.1 bits (169), Expect = 5e-12
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F +L + L+DN + LP + + V+ LD+ RN+I ++ E I + L V
Sbjct: 55 FFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPES----ISFCKALQV 109
Query: 70 ADNQISEIEK--DALPKGLKHVHLGIN--KLNTLNGALRDLDDLEWIFINANNLKSIENE 125
AD + + + ++ P+ L +N L +L + +L +L + + N L + +
Sbjct: 110 ADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDS 169
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L T+ ++++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S
Sbjct: 170 L-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVS 228
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L ++ + L +L I+ N L+ + + LK L L + N +T+ + +
Sbjct: 229 ENRLERL-PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP-EAVG 286
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L+ + L+ NQ+ L S+ L
Sbjct: 287 ECESLTELVLTENQLLTLPKSIGKL 311
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/240 (25%), Positives = 106/240 (44%), Gaps = 7/240 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N L LP + Q L ++ LDL N+I L E + L+ L + NQ+SE+ ++
Sbjct: 158 LRENLLTYLPDSLTQ-LRRLEELDLGNNEIYNLPES-IGALLHLKDLWLDGNQLSELPQE 215
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
K L + + N+L L + L L + I+ N L++I + + K KK+ ++
Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIG-KLKKLSILKVD 274
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N L LP + SL L N + +L +++ K + L + NK+ L K +
Sbjct: 275 QNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPK-EIGG 333
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L + N L + + L L++ N + L + L +L + LS NQ
Sbjct: 334 CCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL-SLTAL-KLKALWLSDNQ 391
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/245 (26%), Positives = 116/245 (47%), Gaps = 4/245 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ L
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRV 277
S+ +L L+ L L N ++E QEI L+ L +D+S N++ L + L + V
Sbjct: 191 ESIGALLHLKDLWLDGNQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLV 249
Query: 278 LELRL 282
+ L
Sbjct: 250 ISQNL 254
Score = 72.1 bits (169), Expect = 5e-12
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F +L + L+DN + LP + + V+ LD+ RN+I ++ E I + L V
Sbjct: 55 FFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPES----ISFCKALQV 109
Query: 70 ADNQISEIEK--DALPKGLKHVHLGIN--KLNTLNGALRDLDDLEWIFINANNLKSIENE 125
AD + + + ++ P+ L +N L +L + +L +L + + N L + +
Sbjct: 110 ADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDS 169
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L T+ ++++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S
Sbjct: 170 L-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVS 228
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L ++ + L +L I+ N L+ + + LK L L + N +T+ + +
Sbjct: 229 ENRLERL-PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP-EAVG 286
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L+ + L+ NQ+ L S+ L
Sbjct: 287 ECESLTELVLTENQLLTLPKSIGKL 311
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/240 (25%), Positives = 106/240 (44%), Gaps = 7/240 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N L LP + Q L ++ LDL N+I L E + L+ L + NQ+SE+ ++
Sbjct: 158 LRENLLTYLPDSLTQ-LRRLEELDLGNNEIYNLPES-IGALLHLKDLWLDGNQLSELPQE 215
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
K L + + N+L L + L L + I+ N L++I + + K KK+ ++
Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIG-KLKKLSILKVD 274
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N L LP + SL L N + +L +++ K + L + NK+ L K +
Sbjct: 275 QNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPK-EIGG 333
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L + N L + + L L++ N + L + L +L + LS NQ
Sbjct: 334 CCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL-SLTAL-KLKALWLSDNQ 391
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/245 (26%), Positives = 116/245 (47%), Gaps = 4/245 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ L
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRV 277
S+ +L L+ L L N ++E QEI L+ L +D+S N++ L + L + V
Sbjct: 191 ESIGALLHLKDLWLDGNQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLV 249
Query: 278 LELRL 282
+ L
Sbjct: 250 ISQNL 254
Score = 72.1 bits (169), Expect = 5e-12
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F +L + L+DN + LP + + V+ LD+ RN+I ++ E I + L V
Sbjct: 55 FFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPES----ISFCKALQV 109
Query: 70 ADNQISEIEK--DALPKGLKHVHLGIN--KLNTLNGALRDLDDLEWIFINANNLKSIENE 125
AD + + + ++ P+ L +N L +L + +L +L + + N L + +
Sbjct: 110 ADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDS 169
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L T+ ++++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S
Sbjct: 170 L-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVS 228
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L ++ + L +L I+ N L+ + + LK L L + N +T+ + +
Sbjct: 229 ENRLERL-PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP-EAVG 286
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L+ + L+ NQ+ L S+ L
Sbjct: 287 ECESLTELVLTENQLLTLPKSIGKL 311
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/240 (25%), Positives = 106/240 (44%), Gaps = 7/240 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N L LP + Q L ++ LDL N+I L E + L+ L + NQ+SE+ ++
Sbjct: 158 LRENLLTYLPDSLTQ-LRRLEELDLGNNEIYNLPES-IGALLHLKDLWLDGNQLSELPQE 215
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
K L + + N+L L + L L + I+ N L++I + + K KK+ ++
Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIG-KLKKLSILKVD 274
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N L LP + SL L N + +L +++ K + L + NK+ L K +
Sbjct: 275 QNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPK-EIGG 333
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L + N L + + L L++ N + L + L +L + LS NQ
Sbjct: 334 CCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL-SLTAL-KLKALWLSDNQ 391
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/245 (26%), Positives = 116/245 (47%), Gaps = 4/245 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ L
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRV 277
S+ +L L+ L L N ++E QEI L+ L +D+S N++ L + L + V
Sbjct: 191 ESIGALLHLKDLWLDGNQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLV 249
Query: 278 LELRL 282
+ L
Sbjct: 250 ISQNL 254
Score = 72.1 bits (169), Expect = 5e-12
Identities = 63/265 (23%), Positives = 130/265 (49%), Gaps = 12/265 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F +L + L+DN + LP + + V+ LD+ RN+I ++ E I + L V
Sbjct: 55 FFQLVKLRKLGLSDNEIQRLPPEIANFMQLVE-LDVSRNEIPEIPES----ISFCKALQV 109
Query: 70 ADNQISEIEK--DALPKGLKHVHLGIN--KLNTLNGALRDLDDLEWIFINANNLKSIENE 125
AD + + + ++ P+ L +N L +L + +L +L + + N L + +
Sbjct: 110 ADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDS 169
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
L T+ ++++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S
Sbjct: 170 L-TQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVS 228
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++E L ++ + L +L I+ N L+ + + LK L L + N +T+ + +
Sbjct: 229 ENRLERL-PEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLP-EAVG 286
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L+ + L+ NQ+ L S+ L
Sbjct: 287 ECESLTELVLTENQLLTLPKSIGKL 311
Score = 58.8 bits (136), Expect = 5e-08
Identities = 62/240 (25%), Positives = 106/240 (44%), Gaps = 7/240 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N L LP + Q L ++ LDL N+I L E + L+ L + NQ+SE+ ++
Sbjct: 158 LRENLLTYLPDSLTQ-LRRLEELDLGNNEIYNLPES-IGALLHLKDLWLDGNQLSELPQE 215
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
K L + + N+L L + L L + I+ N L++I + + K KK+ ++
Sbjct: 216 IGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIG-KLKKLSILKVD 274
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N L LP + SL L N + +L +++ K + L + NK+ L K +
Sbjct: 275 QNRLTQLPEAVGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNKLVSLPK-EIGG 333
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L + N L + + L L++ N + L + L +L + LS NQ
Sbjct: 334 CCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL-SLTAL-KLKALWLSDNQ 391
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 82.2 bits (194), Expect = 4e-15
Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 16/269 (5%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQIS 75
+ SL +N L ELP + L L ++TL+L N I+ L +E F + +L+HL VA N++S
Sbjct: 78 HLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLS 137
Query: 76 EIEKDALPKGLKHVHLGINK-LNTLNGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
+ LP+ L+ L N+ + + L ++++ N L + + + ++
Sbjct: 138 -VAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEA 196
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKI-- 189
+ + ++N+L LP L PSL+ L+ N I + L + L + L N++
Sbjct: 197 IATLSLSNNQLSYLPPSLP--PSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTD 254
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRR 249
L F++ L LD+++N+L + L ++L L+L N + + + G R
Sbjct: 255 SGLDATTFSKLHSLEYLDLSHNQLTTVPAGLP--RTLAILHLGRNRIRQVEAARLHGARG 312
Query: 250 LSVIDLSHNQI---SLLTGSLENLVDVET 275
L + L HNQ+ L G+L L + T
Sbjct: 313 LRYLLLQHNQLGSSGLPAGALRPLRGLHT 341
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 81.8 bits (193), Expect = 6e-15
Identities = 75/268 (27%), Positives = 125/268 (46%), Gaps = 10/268 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+DN + LP V + V+ LD+ RN I ++ E + + LE + N +S +
Sbjct: 66 LSDNEIQRLPPEVANFMQLVE-LDVSRNDIPEIPES-IKFCKALEIADFSGNPLSRLPDG 123
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L H+ L L L G + +L +L + + N LKS+ L K QL
Sbjct: 124 FTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQL-DLG 182
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N+L+ LP L +P+L+ L+ N + +L L R L+ + +S N++E L +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA-ELGG 241
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L +L ++ N L+ L + LK L L + N + E + + I LS + L+ N
Sbjct: 242 LVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT-EAIGDCENLSELILTENL 300
Query: 260 ISLLTGSLENLVDVETRVLELRLDHNHI 287
+ L SL L T++ L +D NH+
Sbjct: 301 LMALPRSLGKL----TKLTNLNVDRNHL 324
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/234 (26%), Positives = 112/234 (47%), Gaps = 4/234 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ K L+ + L N++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N++ I + K +++ + N L LP + SL
Sbjct: 73 RLPPEVANFMQLVELDVSRNDIPEIPESIKF-CKALEIADFSGNPLSRLPDGFTQLRSLA 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L ++++L + NL+ + L N ++ L + KL +LD+ N+L+ L
Sbjct: 132 HLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPA-SLSFLVKLEQLDLGGNDLEVLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLV 271
+L +L +LR L L N ++ E+ LRRL +D+S N++ L L LV
Sbjct: 191 DTLGALPNLRELWLDRNQLSALP-PELGNLRRLVCLDVSENRLEELPAELGGLV 243
>BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 81.8 bits (193), Expect = 6e-15
Identities = 69/288 (23%), Positives = 130/288 (45%), Gaps = 9/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ + ++ + +N L P+ ++ + +L+ L F+ NNI+S+ E + +L+
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLI 284
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS 240
I N I+F+ + F +L L + L +L L LT ++
Sbjct: 285 TIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 241 LQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 345 QTVCNQLPNLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 387
Score = 64.1 bits (149), Expect = 1e-09
Identities = 65/274 (23%), Positives = 120/274 (43%), Gaps = 9/274 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
+ ++H +N + SL + SL++L NN+ ++ NL +G N
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNN 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLT-HNYMTEFSLQEIKG 246
I + + F L + N ++++ S + L LR L L + +TEF ++ G
Sbjct: 269 IRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEF--PDLTG 326
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
L + L+ QIS L ++ N + +VL+L
Sbjct: 327 TANLESLTLTGAQISSLPQTVCNQLP-NLQVLDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F L ++ L N+L E P ++ L ++K L N I + E+ F L
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSL 283
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 284 ITIHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 337
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 396
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 397 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 454
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 455 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 494
Score = 49.6 bits (113), Expect = 3e-05
Identities = 59/224 (26%), Positives = 92/224 (41%), Gaps = 13/224 (5%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL+ L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L SL L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + S N + SI + NP L H Y+
Sbjct: 247 DEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
>BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 5 protein.
Length = 907
Score = 81.8 bits (193), Expect = 6e-15
Identities = 69/288 (23%), Positives = 130/288 (45%), Gaps = 9/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ + ++ + +N L P+ ++ + +L+ L F+ NNI+S+ E + +L+
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLI 284
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS 240
I N I+F+ + F +L L + L +L L LT ++
Sbjct: 285 TIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 241 LQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 345 QTVCNQLPNLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 387
Score = 64.1 bits (149), Expect = 1e-09
Identities = 65/274 (23%), Positives = 120/274 (43%), Gaps = 9/274 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
+ ++H +N + SL + SL++L NN+ ++ NL +G N
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNN 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLT-HNYMTEFSLQEIKG 246
I + + F L + N ++++ S + L LR L L + +TEF ++ G
Sbjct: 269 IRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEF--PDLTG 326
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
L + L+ QIS L ++ N + +VL+L
Sbjct: 327 TANLESLTLTGAQISSLPQTVCNQLP-NLQVLDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F L ++ L N+L E P ++ L ++K L N I + E+ F L
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSL 283
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 284 ITIHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 337
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 396
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 397 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 454
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 455 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 494
Score = 49.6 bits (113), Expect = 3e-05
Identities = 59/224 (26%), Positives = 92/224 (41%), Gaps = 13/224 (5%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL+ L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L SL L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + S N + SI + NP L H Y+
Sbjct: 247 DEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 81.8 bits (193), Expect = 6e-15
Identities = 75/268 (27%), Positives = 125/268 (46%), Gaps = 10/268 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+DN + LP V + V+ LD+ RN I ++ E + + LE + N +S +
Sbjct: 66 LSDNEIQRLPPEVANFMQLVE-LDVSRNDIPEIPES-IKFCKALEIADFSGNPLSRLPDG 123
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L H+ L L L G + +L +L + + N LKS+ L K QL
Sbjct: 124 FTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQL-DLG 182
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N+L+ LP L +P+L+ L+ N + +L L R L+ + +S N++E L +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA-ELGG 241
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L +L ++ N L+ L + LK L L + N + E + + I LS + L+ N
Sbjct: 242 LVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT-EAIGDCENLSELILTENL 300
Query: 260 ISLLTGSLENLVDVETRVLELRLDHNHI 287
+ L SL L T++ L +D NH+
Sbjct: 301 LMALPRSLGKL----TKLTNLNVDRNHL 324
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/234 (26%), Positives = 112/234 (47%), Gaps = 4/234 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ K L+ + L N++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N++ I + K +++ + N L LP + SL
Sbjct: 73 RLPPEVANFMQLVELDVSRNDIPEIPESIKF-CKALEIADFSGNPLSRLPDGFTQLRSLA 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L ++++L + NL+ + L N ++ L + KL +LD+ N+L+ L
Sbjct: 132 HLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPA-SLSFLVKLEQLDLGGNDLEVLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLV 271
+L +L +LR L L N ++ E+ LRRL +D+S N++ L L LV
Sbjct: 191 DTLGALPNLRELWLDRNQLSALP-PELGNLRRLVCLDVSENRLEELPAELGGLV 243
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 81.8 bits (193), Expect = 6e-15
Identities = 75/268 (27%), Positives = 125/268 (46%), Gaps = 10/268 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+DN + LP V + V+ LD+ RN I ++ E + + LE + N +S +
Sbjct: 66 LSDNEIQRLPPEVANFMQLVE-LDVSRNDIPEIPES-IKFCKALEIADFSGNPLSRLPDG 123
Query: 81 ALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L H+ L L L G + +L +L + + N LKS+ L K QL
Sbjct: 124 FTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQL-DLG 182
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
N+L+ LP L +P+L+ L+ N + +L L R L+ + +S N++E L +
Sbjct: 183 GNDLEVLPDTLGALPNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLEELPA-ELGG 241
Query: 200 AEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L +L ++ N L+ L + LK L L + N + E + + I LS + L+ N
Sbjct: 242 LVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVT-EAIGDCENLSELILTENL 300
Query: 260 ISLLTGSLENLVDVETRVLELRLDHNHI 287
+ L SL L T++ L +D NH+
Sbjct: 301 LMALPRSLGKL----TKLTNLNVDRNHL 324
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/234 (26%), Positives = 112/234 (47%), Gaps = 4/234 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ K L+ + L N++
Sbjct: 13 HVESVDKRHCSLQAVPEEIYRYSRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N++ I + K +++ + N L LP + SL
Sbjct: 73 RLPPEVANFMQLVELDVSRNDIPEIPESIKF-CKALEIADFSGNPLSRLPDGFTQLRSLA 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L ++++L + NL+ + L N ++ L + KL +LD+ N+L+ L
Sbjct: 132 HLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPA-SLSFLVKLEQLDLGGNDLEVLP 190
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLV 271
+L +L +LR L L N ++ E+ LRRL +D+S N++ L L LV
Sbjct: 191 DTLGALPNLRELWLDRNQLSALP-PELGNLRRLVCLDVSENRLEELPAELGGLV 243
>AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-coupled
receptor HG38 protein.
Length = 907
Score = 81.8 bits (193), Expect = 6e-15
Identities = 69/288 (23%), Positives = 130/288 (45%), Gaps = 9/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ + ++ + +N L P+ ++ + +L+ L F+ NNI+S+ E + +L+
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLI 284
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS 240
I N I+F+ + F +L L + L +L L LT ++
Sbjct: 285 TIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 241 LQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 345 QTVCNQLPNLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 387
Score = 64.1 bits (149), Expect = 1e-09
Identities = 65/274 (23%), Positives = 120/274 (43%), Gaps = 9/274 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
+ ++H +N + SL + SL++L NN+ ++ NL +G N
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNN 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLT-HNYMTEFSLQEIKG 246
I + + F L + N ++++ S + L LR L L + +TEF ++ G
Sbjct: 269 IRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEF--PDLTG 326
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
L + L+ QIS L ++ N + +VL+L
Sbjct: 327 TANLESLTLTGAQISSLPQTVCNQLP-NLQVLDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F L ++ L N+L E P ++ L ++K L N I + E+ F L
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSL 283
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 284 ITIHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 337
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 396
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 397 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 454
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 455 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 494
Score = 49.6 bits (113), Expect = 3e-05
Identities = 59/224 (26%), Positives = 92/224 (41%), Gaps = 13/224 (5%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL+ L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L SL L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + S N + SI + NP L H Y+
Sbjct: 247 DEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 81.4 bits (192), Expect = 8e-15
Identities = 57/202 (28%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L ++L NKL +L + L +L + ++ N+L S+ + L KK++++ HN+L+
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLRE 183
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
+PS + + SL +LY N I ++++ ++ L + + NKI+ L + E L
Sbjct: 184 IPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA-EIGELCNLIT 242
Query: 206 LDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
LD+A+N+L++L + + + L+L HN + + I L LS + L +N++S +
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPR 301
Query: 266 SLENLVDVETRVLELRLDHNHI 287
SL +E EL L++N+I
Sbjct: 302 SLAKCSALE----ELNLENNNI 319
Score = 79.4 bits (187), Expect = 3e-14
Identities = 92/397 (23%), Positives = 167/397 (42%), Gaps = 21/397 (5%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L++NSL LP L +L ++ LDL NK+ ++ +R + L L + N+I+ +EK
Sbjct: 152 ALSENSLTSLPDS-LDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEK 209
Query: 80 DA--LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L K L + + NK+ L + +L +L + + N L+ + E+ ++ +
Sbjct: 210 DIKNLSK-LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGN-CTQITNLD 267
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HNEL LP + + SL L N + ++ +L K L + L N I L +
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Query: 198 TEAEKLAELDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ KL L +A N + Y G ++ LN+ HN + + + LS +++
Sbjct: 328 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 387
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXX 316
NQ++ SL T ++EL L N + ++K+
Sbjct: 388 DNQLT----SLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PH 442
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADL 376
+ N + +L +L L++L+ +N +T L + L +L L
Sbjct: 443 GLGNLRKLRELDLEENKLESL-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGL 501
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVL 413
N L++ I + ++ ++YL DNP L
Sbjct: 502 GEN--------LLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/276 (22%), Positives = 128/276 (46%), Gaps = 9/276 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + + L ++ TLD+ N++ L +E + ++ +
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKE-IGNCTQITN 265
Query: 67 LLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + N++ ++ D + L + L N+L+ + +L LE + + NN+ ++
Sbjct: 266 LDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPE 324
Query: 125 ELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRI 182
L + K+ + A N Q P ++ SL N I + + +++ L ++
Sbjct: 325 SLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 384
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
+ N++ L D F + EL++A N+L + + L SL L L++N + +
Sbjct: 385 NMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-H 442
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+ LR+L +DL N++ L + L D++ VL
Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVL 478
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
++N + I+ + + + + + LPS +K + L LY Y N ++SL +
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGC 144
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
NLM + LS N + L D +KL LD+ +N+L+ + + L SL L L N
Sbjct: 145 LVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNR 203
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET-RVLELRLDH 284
+T ++IK L +LS++ + N+I L + L ++ T V +L+H
Sbjct: 204 ITTVE-KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 322 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 381
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 382 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 441
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 442 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 500
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 501 LGENLLTHLPEEIGT-LENLEEL 522
Score = 54.8 bits (126), Expect = 8e-07
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 24/247 (9%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
K ++ +L +N++ LP +L L + +L L RN + L +
Sbjct: 305 KCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEH 364
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
N+I++I P G+ ++KLN ++D N L S+ + T
Sbjct: 365 NRINKI-----PFGIFSRAKVLSKLN-----MKD-----------NQLTSLPLDFGTWTS 403
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
++L + A N+L +P D+ + SL+ L N +K L L R L + L NK+E
Sbjct: 404 MVEL-NLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L ++ + L +L + N+L L + L +L +L L N +T +EI L L
Sbjct: 463 L-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP-EEIGTLENLE 520
Query: 252 VIDLSHN 258
+ L+ N
Sbjct: 521 ELYLNDN 527
>BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein.
Length = 927
Score = 81.4 bits (192), Expect = 8e-15
Identities = 60/245 (24%), Positives = 113/245 (46%), Gaps = 4/245 (1%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L +N L +P ++ L +++L L N IT + E+ F + +L HL + DN ++E+
Sbjct: 87 TLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPV 146
Query: 80 DALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
L L+ + L +NK++++ + A +L L + ++ N ++S+ ++ +
Sbjct: 147 HHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETL 206
Query: 137 HAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD 195
+N L P +K +PSL+ L F+ N+I + + L+R I L N + F+
Sbjct: 207 DLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNS 266
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L L I + +L L L LT ++ + + L +DL
Sbjct: 267 AFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDL 326
Query: 256 SHNQI 260
S+N I
Sbjct: 327 SYNNI 331
Score = 79.0 bits (186), Expect = 4e-14
Identities = 66/257 (25%), Positives = 118/257 (45%), Gaps = 4/257 (1%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F L + + L DNSL E+P H L +LP ++ L L NKI+ + + F ++ L
Sbjct: 122 EDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 181
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + +N+I + + L+ + L N L A++ L L+ + ++N++ I +
Sbjct: 182 LHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPD 241
Query: 125 ELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
++ IH N L + S + L SL G ++ L + +L +
Sbjct: 242 GAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLT 301
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
L+ KI + + E + L LD++YN ++ L S +L ++L N + +
Sbjct: 302 LTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALEEISLQRNQIYQIKEGT 360
Query: 244 IKGLRRLSVIDLSHNQI 260
+GL L ++DLS N I
Sbjct: 361 FQGLISLRILDLSRNLI 377
Score = 73.3 bits (172), Expect = 2e-12
Identities = 86/326 (26%), Positives = 138/326 (42%), Gaps = 13/326 (3%)
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIE 123
L +A N +S I AL K LK + L N+L T+ + A+R L L+ + ++AN++ S+
Sbjct: 62 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 121
Query: 124 NELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMR 181
+ +++ + N L +P L +P+LQ+L N I S+ D +L+
Sbjct: 122 EDSFEGLVQLRHLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIPDFAFTNLSSLVV 181
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
+ L NKI L++ F + L LD+ YN L ++++L SL+ L N ++
Sbjct: 182 LHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPD 241
Query: 242 QEIKGLRRLSVIDLSHNQISLLTGS-LENLVDVETRVLELRLDHNHIFXXXXXXXXXXXX 300
G L I L N +S + S NL D+ + V+ +
Sbjct: 242 GAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIR----GASMVQQFPNLTGTVHL 297
Query: 301 XXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-T 359
I I +SYN+I L S +LEE+ N I
Sbjct: 298 ESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL--PSFNGCHALEEISLQRNQIYQ 355
Query: 360 VLDKDFHGLPSLCSADLSFNKIHTVN 385
+ + F GL SL DLS N IH ++
Sbjct: 356 IKEGTFQGLISLRILDLSRNLIHEIH 381
Score = 62.1 bits (144), Expect = 5e-09
Identities = 60/254 (23%), Positives = 116/254 (45%), Gaps = 8/254 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N + L +H L +++TLDL N + + + + + L
Sbjct: 168 IPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQA-IKALPSL 226
Query: 65 EHLLVADNQISEIEKDALPKG--LKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
+ L N IS I A L+ +HL N L+ + N A +L DL + I ++
Sbjct: 227 KELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQ 286
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
L T ++ + ++ S+P++L + L++L NNI+ L + L
Sbjct: 287 QFPNL-TGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDL-PSFNGCHALE 344
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEF 239
I L N+I + + F L LD++ N + ++ + +L + L+++ N +T F
Sbjct: 345 EISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSF 404
Query: 240 SLQEIKGLRRLSVI 253
+ + GL +L ++
Sbjct: 405 PTEGLNGLNQLKLV 418
Score = 48.0 bits (109), Expect = 9e-05
Identities = 68/271 (25%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
FT+A +LA D+++ K L+G LK L+ L L +N + + I+GL L + L
Sbjct: 58 FTQALQLAGNDLSFIHPKALSG----LKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLD 113
Query: 257 HNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX-XXXXXXXXXXXIQKIX 314
N I S+ S E LV + L LD N + I I
Sbjct: 114 ANHITSVPEDSFEGLVQLR----HLWLDDNSLTEVPVHHLSNLPTLQALTLALNKISSIP 169
Query: 315 XXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSA 374
+ N I +L + L +LE L ++NN+ + LPSL
Sbjct: 170 DFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSL--K 227
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV-LCDDHLYELVTVFESLNARVS 433
+L F H+ + ++ +G P + I+L DNP+ + + ++ SL R
Sbjct: 228 ELGF---HSNSISVIPDG--AFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIR-- 280
Query: 434 GASTCVA-PQTTAPILMRALNDIGPKKENSP 463
GAS P T + + +L G K + P
Sbjct: 281 GASMVQQFPNLTGTVHLESLTLTGTKISSIP 311
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 81.4 bits (192), Expect = 8e-15
Identities = 57/202 (28%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L ++L NKL +L + L +L + ++ N+L S+ + L KK++++ HN+L+
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLRE 183
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
+PS + + SL +LY N I ++++ ++ L + + NKI+ L + E L
Sbjct: 184 IPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA-EIGELCNLIT 242
Query: 206 LDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
LD+A+N+L++L + + + L+L HN + + I L LS + L +N++S +
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPR 301
Query: 266 SLENLVDVETRVLELRLDHNHI 287
SL +E EL L++N+I
Sbjct: 302 SLAKCSALE----ELNLENNNI 319
Score = 79.4 bits (187), Expect = 3e-14
Identities = 92/397 (23%), Positives = 167/397 (42%), Gaps = 21/397 (5%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L++NSL LP L +L ++ LDL NK+ ++ +R + L L + N+I+ +EK
Sbjct: 152 ALSENSLTSLPDS-LDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEK 209
Query: 80 DA--LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L K L + + NK+ L + +L +L + + N L+ + E+ ++ +
Sbjct: 210 DIKNLSK-LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGN-CTQITNLD 267
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HNEL LP + + SL L N + ++ +L K L + L N I L +
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Query: 198 TEAEKLAELDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ KL L +A N + Y G ++ LN+ HN + + + LS +++
Sbjct: 328 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 387
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXX 316
NQ++ SL T ++EL L N + ++K+
Sbjct: 388 DNQLT----SLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PH 442
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADL 376
+ N + +L +L L++L+ +N +T L + L +L L
Sbjct: 443 GLGNLRKLRELDLEENKLESL-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGL 501
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVL 413
N L++ I + ++ ++YL DNP L
Sbjct: 502 GEN--------LLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/276 (22%), Positives = 128/276 (46%), Gaps = 9/276 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + + L ++ TLD+ N++ L +E + ++ +
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKE-IGNCTQITN 265
Query: 67 LLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + N++ ++ D + L + L N+L+ + +L LE + + NN+ ++
Sbjct: 266 LDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPE 324
Query: 125 ELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRI 182
L + K+ + A N Q P ++ SL N I + + +++ L ++
Sbjct: 325 SLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 384
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
+ N++ L D F + EL++A N+L + + L SL L L++N + +
Sbjct: 385 NMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-H 442
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+ LR+L +DL N++ L + L D++ VL
Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVL 478
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
++N + I+ + + + + + LPS +K + L LY Y N ++SL +
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGC 144
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
NLM + LS N + L D +KL LD+ +N+L+ + + L SL L L N
Sbjct: 145 LVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNR 203
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET-RVLELRLDH 284
+T ++IK L +LS++ + N+I L + L ++ T V +L+H
Sbjct: 204 ITTVE-KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 322 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 381
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 382 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 441
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 442 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 500
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 501 LGENLLTHLPEEIGT-LENLEEL 522
Score = 54.8 bits (126), Expect = 8e-07
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 24/247 (9%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
K ++ +L +N++ LP +L L + +L L RN + L +
Sbjct: 305 KCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEH 364
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
N+I++I P G+ ++KLN ++D N L S+ + T
Sbjct: 365 NRINKI-----PFGIFSRAKVLSKLN-----MKD-----------NQLTSLPLDFGTWTS 403
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
++L + A N+L +P D+ + SL+ L N +K L L R L + L NK+E
Sbjct: 404 MVEL-NLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L ++ + L +L + N+L L + L +L +L L N +T +EI L L
Sbjct: 463 L-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP-EEIGTLENLE 520
Query: 252 VIDLSHN 258
+ L+ N
Sbjct: 521 ELYLNDN 527
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 81.4 bits (192), Expect = 8e-15
Identities = 57/202 (28%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L ++L NKL +L + L +L + ++ N+L S+ + L KK++++ HN+L+
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLRE 183
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
+PS + + SL +LY N I ++++ ++ L + + NKI+ L + E L
Sbjct: 184 IPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA-EIGELCNLIT 242
Query: 206 LDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
LD+A+N+L++L + + + L+L HN + + I L LS + L +N++S +
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPR 301
Query: 266 SLENLVDVETRVLELRLDHNHI 287
SL +E EL L++N+I
Sbjct: 302 SLAKCSALE----ELNLENNNI 319
Score = 79.4 bits (187), Expect = 3e-14
Identities = 92/397 (23%), Positives = 167/397 (42%), Gaps = 21/397 (5%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L++NSL LP L +L ++ LDL NK+ ++ +R + L L + N+I+ +EK
Sbjct: 152 ALSENSLTSLPDS-LDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEK 209
Query: 80 DA--LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L K L + + NK+ L + +L +L + + N L+ + E+ ++ +
Sbjct: 210 DIKNLSK-LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGN-CTQITNLD 267
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HNEL LP + + SL L N + ++ +L K L + L N I L +
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Query: 198 TEAEKLAELDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ KL L +A N + Y G ++ LN+ HN + + + LS +++
Sbjct: 328 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 387
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXX 316
NQ++ SL T ++EL L N + ++K+
Sbjct: 388 DNQLT----SLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PH 442
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADL 376
+ N + +L +L L++L+ +N +T L + L +L L
Sbjct: 443 GLGNLRKLRELDLEENKLESL-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGL 501
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVL 413
N L++ I + ++ ++YL DNP L
Sbjct: 502 GEN--------LLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/276 (22%), Positives = 128/276 (46%), Gaps = 9/276 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + + L ++ TLD+ N++ L +E + ++ +
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKE-IGNCTQITN 265
Query: 67 LLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + N++ ++ D + L + L N+L+ + +L LE + + NN+ ++
Sbjct: 266 LDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPE 324
Query: 125 ELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRI 182
L + K+ + A N Q P ++ SL N I + + +++ L ++
Sbjct: 325 SLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 384
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
+ N++ L D F + EL++A N+L + + L SL L L++N + +
Sbjct: 385 NMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-H 442
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+ LR+L +DL N++ L + L D++ VL
Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVL 478
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
++N + I+ + + + + + LPS +K + L LY Y N ++SL +
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGC 144
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
NLM + LS N + L D +KL LD+ +N+L+ + + L SL L L N
Sbjct: 145 LVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNR 203
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET-RVLELRLDH 284
+T ++IK L +LS++ + N+I L + L ++ T V +L+H
Sbjct: 204 ITTVE-KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 322 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 381
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 382 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 441
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 442 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 500
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 501 LGENLLTHLPEEIGT-LENLEEL 522
Score = 54.8 bits (126), Expect = 8e-07
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 24/247 (9%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
K ++ +L +N++ LP +L L + +L L RN + L +
Sbjct: 305 KCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEH 364
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
N+I++I P G+ ++KLN ++D N L S+ + T
Sbjct: 365 NRINKI-----PFGIFSRAKVLSKLN-----MKD-----------NQLTSLPLDFGTWTS 403
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
++L + A N+L +P D+ + SL+ L N +K L L R L + L NK+E
Sbjct: 404 MVEL-NLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L ++ + L +L + N+L L + L +L +L L N +T +EI L L
Sbjct: 463 L-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP-EEIGTLENLE 520
Query: 252 VIDLSHN 258
+ L+ N
Sbjct: 521 ELYLNDN 527
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 81.4 bits (192), Expect = 8e-15
Identities = 57/202 (28%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L ++L NKL +L + L +L + ++ N+L S+ + L KK++++ HN+L+
Sbjct: 125 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLRE 183
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
+PS + + SL +LY N I ++++ ++ L + + NKI+ L + E L
Sbjct: 184 IPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA-EIGELCNLIT 242
Query: 206 LDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
LD+A+N+L++L + + + L+L HN + + I L LS + L +N++S +
Sbjct: 243 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPR 301
Query: 266 SLENLVDVETRVLELRLDHNHI 287
SL +E EL L++N+I
Sbjct: 302 SLAKCSALE----ELNLENNNI 319
Score = 79.4 bits (187), Expect = 3e-14
Identities = 92/397 (23%), Positives = 167/397 (42%), Gaps = 21/397 (5%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L++NSL LP L +L ++ LDL NK+ ++ +R + L L + N+I+ +EK
Sbjct: 152 ALSENSLTSLPDS-LDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEK 209
Query: 80 DA--LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L K L + + NK+ L + +L +L + + N L+ + E+ ++ +
Sbjct: 210 DIKNLSK-LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGN-CTQITNLD 267
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HNEL LP + + SL L N + ++ +L K L + L N I L +
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 327
Query: 198 TEAEKLAELDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ KL L +A N + Y G ++ LN+ HN + + + LS +++
Sbjct: 328 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 387
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXX 316
NQ++ SL T ++EL L N + ++K+
Sbjct: 388 DNQLT----SLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PH 442
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADL 376
+ N + +L +L L++L+ +N +T L + L +L L
Sbjct: 443 GLGNLRKLRELDLEENKLESL-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGL 501
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVL 413
N L++ I + ++ ++YL DNP L
Sbjct: 502 GEN--------LLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/276 (22%), Positives = 128/276 (46%), Gaps = 9/276 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + + L ++ TLD+ N++ L +E + ++ +
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKE-IGNCTQITN 265
Query: 67 LLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + N++ ++ D + L + L N+L+ + +L LE + + NN+ ++
Sbjct: 266 LDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPE 324
Query: 125 ELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRI 182
L + K+ + A N Q P ++ SL N I + + +++ L ++
Sbjct: 325 SLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 384
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
+ N++ L D F + EL++A N+L + + L SL L L++N + +
Sbjct: 385 NMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-H 442
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+ LR+L +DL N++ L + L D++ VL
Sbjct: 443 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVL 478
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
++N + I+ + + + + + LPS +K + L LY Y N ++SL +
Sbjct: 85 SSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGC 144
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
NLM + LS N + L D +KL LD+ +N+L+ + + L SL L L N
Sbjct: 145 LVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNR 203
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET-RVLELRLDH 284
+T ++IK L +LS++ + N+I L + L ++ T V +L+H
Sbjct: 204 ITTVE-KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 252
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 322 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 381
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 382 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 441
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 442 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 500
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 501 LGENLLTHLPEEIGT-LENLEEL 522
Score = 54.8 bits (126), Expect = 8e-07
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 24/247 (9%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
K ++ +L +N++ LP +L L + +L L RN + L +
Sbjct: 305 KCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEH 364
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
N+I++I P G+ ++KLN ++D N L S+ + T
Sbjct: 365 NRINKI-----PFGIFSRAKVLSKLN-----MKD-----------NQLTSLPLDFGTWTS 403
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
++L + A N+L +P D+ + SL+ L N +K L L R L + L NK+E
Sbjct: 404 MVEL-NLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L ++ + L +L + N+L L + L +L +L L N +T +EI L L
Sbjct: 463 L-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP-EEIGTLENLE 520
Query: 252 VIDLSHN 258
+ L+ N
Sbjct: 521 ELYLNDN 527
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 81.4 bits (192), Expect = 8e-15
Identities = 57/202 (28%), Positives = 108/202 (53%), Gaps = 7/202 (3%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L ++L NKL +L + L +L + ++ N+L S+ + L KK++++ HN+L+
Sbjct: 127 LTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDN-LKKLRMLDLRHNKLRE 185
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
+PS + + SL +LY N I ++++ ++ L + + NKI+ L + E L
Sbjct: 186 IPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPA-EIGELCNLIT 244
Query: 206 LDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
LD+A+N+L++L + + + L+L HN + + I L LS + L +N++S +
Sbjct: 245 LDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPR 303
Query: 266 SLENLVDVETRVLELRLDHNHI 287
SL +E EL L++N+I
Sbjct: 304 SLAKCSALE----ELNLENNNI 321
Score = 79.4 bits (187), Expect = 3e-14
Identities = 92/397 (23%), Positives = 167/397 (42%), Gaps = 21/397 (5%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L++NSL LP L +L ++ LDL NK+ ++ +R + L L + N+I+ +EK
Sbjct: 154 ALSENSLTSLPDS-LDNLKKLRMLDLRHNKLREIPSVVYR-LDSLTTLYLRFNRITTVEK 211
Query: 80 DA--LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L K L + + NK+ L + +L +L + + N L+ + E+ ++ +
Sbjct: 212 DIKNLSK-LSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGN-CTQITNLD 269
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HNEL LP + + SL L N + ++ +L K L + L N I L +
Sbjct: 270 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLL 329
Query: 198 TEAEKLAELDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ KL L +A N + Y G ++ LN+ HN + + + LS +++
Sbjct: 330 SSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMK 389
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXX 316
NQ++ SL T ++EL L N + ++K+
Sbjct: 390 DNQLT----SLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKL-PH 444
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADL 376
+ N + +L +L L++L+ +N +T L + L +L L
Sbjct: 445 GLGNLRKLRELDLEENKLESL-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGL 503
Query: 377 SFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVL 413
N L++ I + ++ ++YL DNP L
Sbjct: 504 GEN--------LLTHLPEEIGTLENLEELYLNDNPNL 532
Score = 68.5 bits (160), Expect = 6e-11
Identities = 62/276 (22%), Positives = 128/276 (46%), Gaps = 9/276 (3%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + + L ++ TLD+ N++ L +E + ++ +
Sbjct: 210 EKDIKNLSKLSMLSIRENKIKQLPAEIGE-LCNLITLDVAHNQLEHLPKE-IGNCTQITN 267
Query: 67 LLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + N++ ++ D + L + L N+L+ + +L LE + + NN+ ++
Sbjct: 268 LDLQHNELLDLP-DTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPE 326
Query: 125 ELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRI 182
L + K+ + A N Q P ++ SL N I + + +++ L ++
Sbjct: 327 SLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKL 386
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
+ N++ L D F + EL++A N+L + + L SL L L++N + +
Sbjct: 387 NMKDNQLTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-H 444
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+ LR+L +DL N++ L + L D++ VL
Sbjct: 445 GLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVL 480
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/170 (27%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
++N + I+ + + + + + LPS +K + L LY Y N ++SL +
Sbjct: 87 SSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGC 146
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
NLM + LS N + L D +KL LD+ +N+L+ + + L SL L L N
Sbjct: 147 LVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNR 205
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET-RVLELRLDH 284
+T ++IK L +LS++ + N+I L + L ++ T V +L+H
Sbjct: 206 ITTVE-KDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEH 254
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 324 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 383
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 384 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 443
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 444 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 502
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 503 LGENLLTHLPEEIGT-LENLEEL 524
Score = 54.8 bits (126), Expect = 8e-07
Identities = 62/247 (25%), Positives = 107/247 (43%), Gaps = 24/247 (9%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
K ++ +L +N++ LP +L L + +L L RN + L +
Sbjct: 307 KCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEH 366
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
N+I++I P G+ ++KLN ++D N L S+ + T
Sbjct: 367 NRINKI-----PFGIFSRAKVLSKLN-----MKD-----------NQLTSLPLDFGTWTS 405
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEF 191
++L + A N+L +P D+ + SL+ L N +K L L R L + L NK+E
Sbjct: 406 MVEL-NLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 464
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L ++ + L +L + N+L L + L +L +L L N +T +EI L L
Sbjct: 465 L-PNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLP-EEIGTLENLE 522
Query: 252 VIDLSHN 258
+ L+ N
Sbjct: 523 ELYLNDN 529
>L01131-1|AAA52301.1| 347|Homo sapiens decorin protein.
Length = 347
Score = 81.0 bits (191), Expect = 1e-14
Identities = 59/197 (29%), Positives = 97/197 (49%), Gaps = 7/197 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ ++L ++ L L NKI+K++ F + +LE L ++ NQ+ E+ +
Sbjct: 88 LQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKEL-PE 146
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIH 137
+PK L+ + N++ + L+ + I + N LKS IEN KK+ I
Sbjct: 147 KMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIR 206
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A + S+P L PSL L+ GN I +D +L+ NL ++GLSFN I +
Sbjct: 207 IADTNITSIPQGLP--PSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGS 264
Query: 197 FTEAEKLAELDIAYNEL 213
L EL + N+L
Sbjct: 265 LANTPHLRELHLDNNKL 281
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 81.0 bits (191), Expect = 1e-14
Identities = 91/381 (23%), Positives = 174/381 (45%), Gaps = 42/381 (11%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK---DALPKGLKHVHLGINKLN 97
++L+L NK++++ F D+ L+ + ++ N++SEI+ + LP L+ V+L N+L
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPN-LQEVYLNNNELT 129
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSL 156
+ + +F+ N ++S+E ++++ + N + + + P +
Sbjct: 130 AVPSLGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPI 189
Query: 157 QSLYFYGNNIKSLDETLQK--SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELK 214
+ L GN I +L+ SR+L+ + LS N+I L F + +L +LD+ N ++
Sbjct: 190 KELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRITQLPVRAF-KLPRLTQLDLNRNRIR 248
Query: 215 YLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ-ISLLTGSLENLVD 272
+ G + + L SL L L N +++ + GL ++ V+ L +N + + +GSL L
Sbjct: 249 LIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGL-- 306
Query: 273 VETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYN 332
T + +L L +N I +I +S+N
Sbjct: 307 --TALHQLHLSNN-----------------------SIARIHRKGWSFCQKLHELVLSFN 341
Query: 333 HITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADLSFNKIHTVNYDLVSK 391
++T L+E S L SL L HN+I+ + + F GL SL DL N+I +
Sbjct: 342 NLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEIS----GTIED 397
Query: 392 SRCTINGVPSILKIYLQDNPV 412
+ +G+ S+ K+ L N +
Sbjct: 398 TSGAFSGLDSLSKLNLGGNAI 418
Score = 79.0 bits (186), Expect = 4e-14
Identities = 66/255 (25%), Positives = 126/255 (49%), Gaps = 11/255 (4%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI-QELEHLLVADNQI 74
++ L+ N++ E+ H P +K L+L N+I L F + + L L ++ N+I
Sbjct: 165 LEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRI 224
Query: 75 SEIEKDA--LPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAK 131
+++ A LP+ L + L N++ + G + L+ LE + + NN+ + +
Sbjct: 225 TQLPVRAFKLPR-LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLS 283
Query: 132 KMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKI 189
KM ++H +N L + S L + +L L+ N+I + + + L + LSFN +
Sbjct: 284 KMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNL 343
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIK 245
L ++ E L+ L +++N + ++ G+ + L+SLR L+L HN ++ E +
Sbjct: 344 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFS 403
Query: 246 GLRRLSVIDLSHNQI 260
GL LS ++L N I
Sbjct: 404 GLDSLSKLNLGGNAI 418
Score = 78.6 bits (185), Expect = 5e-14
Identities = 94/433 (21%), Positives = 187/433 (43%), Gaps = 42/433 (9%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L+ N L E+ + LP+++ ++L NK++++ F D+ L+ + + +N+++ +
Sbjct: 74 NLSYNKLSEIDPAGFEDLPNLQEVNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS 133
Query: 80 -DALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A + + L NK+ ++ G+ L+ LE + ++ NN+ + N ++ ++
Sbjct: 134 LGAASSHVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELN 193
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDF 197
A N + +L +L L SR+L+ + LS N+I L F
Sbjct: 194 LAGNRIGTL--ELGAFDGL-------------------SRSLLTLRLSKNRITQLPVRAF 232
Query: 198 TEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ +L +LD+ N ++ + G + + L SL L L N +++ + GL ++ V+ L
Sbjct: 233 -KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLE 291
Query: 257 HNQ-ISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXX-XXXXXXXXXXXXXXXIQKIX 314
+N + + +GSL L T + +L L +N I + ++
Sbjct: 292 YNSLVEVNSGSLYGL----TALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLD 347
Query: 315 XXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD----FHGLPS 370
+S+N I+ + E + L SL L HN I+ +D F GL S
Sbjct: 348 EESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDS 407
Query: 371 LCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNA 430
L +L N I +V +D K + ++ ++++ + LCD L L
Sbjct: 408 LSKLNLGGNAIRSVQFDAFVKMK-------NLKELHISSDSFLCDCQLKWLPPWLIGRML 460
Query: 431 RVSGASTCVAPQT 443
+ +TC P++
Sbjct: 461 QAFVTATCAHPES 473
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/206 (22%), Positives = 90/206 (43%), Gaps = 8/206 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + L N + + Q L ++ L L RN I+KLT+ F + ++ L +
Sbjct: 233 KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 292
Query: 72 NQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N + E+ +L L +HL N + ++ L + ++ NNL ++ E
Sbjct: 293 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 352
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIK-SLDET---LQKSRNLMRIG 183
+ + ++ +HN + + K + SL+ L N I ++++T +L ++
Sbjct: 353 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLN 412
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIA 209
L N I + D F + + L EL I+
Sbjct: 413 LGGNAIRSVQFDAFVKMKNLKELHIS 438
Score = 34.3 bits (75), Expect = 1.2
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED---FRDI 61
L E +L + L+ NS+ + + L ++ LDL N+I+ E+ F +
Sbjct: 346 LDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL 405
Query: 62 QELEHLLVADNQISEIEKDAL--PKGLKHVHL 91
L L + N I ++ DA K LK +H+
Sbjct: 406 DSLSKLNLGGNAIRSVQFDAFVKMKNLKELHI 437
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 80.6 bits (190), Expect = 1e-14
Identities = 63/261 (24%), Positives = 126/261 (48%), Gaps = 8/261 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+ + ++ + +N L P+ ++ + +L+ L+FY N I+ + + + +R
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELR 284
Query: 182 IGLSFNKIEFLTK-DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
L+ N +T+ D T L L + ++ L ++ L +L+ L+L++N + +
Sbjct: 285 T-LTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLED- 342
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L ++L IDL HN+I
Sbjct: 343 -LPSFSVCQKLQKIDLRHNEI 362
Score = 62.9 bits (146), Expect = 3e-09
Identities = 67/281 (23%), Positives = 122/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L + L ++TLDL N + + R + L
Sbjct: 201 IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA-IRTLSNL 259
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ L DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 260 KELHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 313
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 372
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 373 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 430
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 431 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 470
Score = 60.9 bits (141), Expect = 1e-08
Identities = 63/280 (22%), Positives = 115/280 (41%), Gaps = 9/280 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
+ ++H +N + SL + SL++L NN+ ++ NL + N
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR 248
I+F+ + F +L L + L +L L LT ++ L
Sbjct: 269 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLP 328
Query: 249 RLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 329 NLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 363
Score = 48.8 bits (111), Expect = 5e-05
Identities = 54/211 (25%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL+ L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L SL L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
+ I + ++ +++ DNP+
Sbjct: 247 --------DEFPTAIRTLSNLKELHFYDNPI 269
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 80.6 bits (190), Expect = 1e-14
Identities = 63/261 (24%), Positives = 126/261 (48%), Gaps = 8/261 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+ + ++ + +N L P+ ++ + +L+ L+FY N I+ + + + +R
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELR 284
Query: 182 IGLSFNKIEFLTK-DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
L+ N +T+ D T L L + ++ L ++ L +L+ L+L++N + +
Sbjct: 285 T-LTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLED- 342
Query: 240 SLQEIKGLRRLSVIDLSHNQI 260
L ++L IDL HN+I
Sbjct: 343 -LPSFSVCQKLQKIDLRHNEI 362
Score = 62.9 bits (146), Expect = 3e-09
Identities = 67/281 (23%), Positives = 122/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + F L + L +N + L + L ++TLDL N + + R + L
Sbjct: 201 IPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA-IRTLSNL 259
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ L DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 260 KELHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 313
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 314 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 372
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 373 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 430
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 431 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 470
Score = 60.9 bits (141), Expect = 1e-08
Identities = 63/280 (22%), Positives = 115/280 (41%), Gaps = 9/280 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
+ ++H +N + SL + SL++L NN+ ++ NL + N
Sbjct: 209 LSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNP 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR 248
I+F+ + F +L L + L +L L LT ++ L
Sbjct: 269 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLP 328
Query: 249 RLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 329 NLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 363
Score = 48.8 bits (111), Expect = 5e-05
Identities = 54/211 (25%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL+ L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L SL L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
+ I + ++ +++ DNP+
Sbjct: 247 --------DEFPTAIRTLSNLKELHFYDNPI 269
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 80.6 bits (190), Expect = 1e-14
Identities = 74/276 (26%), Positives = 131/276 (47%), Gaps = 13/276 (4%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
++ +L +N L E+P + L ++ L L RN+ +L L L V+ N+++
Sbjct: 65 IEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLT 124
Query: 76 EIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKM 133
+ + + + L+ ++L N+L L L L LE + ++ N L + + L + ++
Sbjct: 125 ALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRLAHLPDSL-SCLSRL 183
Query: 134 QLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLT 193
+ + HN+L + P L + +L+ L N ++ L E + R L + LS ++ L
Sbjct: 184 RTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLP 243
Query: 194 KDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF--SLQEIKGLRRLS 251
F E L L + N L+ L L+ L+ LNL+ N EF +L + GL L
Sbjct: 244 A-GFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGLEELY 302
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
LS NQ++ S+ +L+ R+L L LD+N I
Sbjct: 303 ---LSRNQLT----SVPSLISGLGRLLTLWLDNNRI 331
Score = 76.6 bits (180), Expect = 2e-13
Identities = 67/261 (25%), Positives = 123/261 (47%), Gaps = 6/261 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--E 78
L N LP V + H+ LD+ N++T L E ++EL L ++ NQ+ + +
Sbjct: 94 LRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQ 153
Query: 79 KDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
AL L+ + + N+L L +L L L + ++ N L + +L + ++ +
Sbjct: 154 LGALAH-LEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQL-LQLVALEELDV 211
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFT 198
+ N L+ LP D+ + +L+ L+ G + +L + +L + L N ++ L F+
Sbjct: 212 SSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPA-QFS 270
Query: 199 EAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
++L L+++ N + +L L L L L+ N +T I GL RL + L +N
Sbjct: 271 CLQRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVP-SLISGLGRLLTLWLDNN 329
Query: 259 QISLLTGSLENLVDVETRVLE 279
+I L S+ L +E VL+
Sbjct: 330 RIRYLPDSIVELTGLEELVLQ 350
Score = 62.9 bits (146), Expect = 3e-09
Identities = 55/240 (22%), Positives = 113/240 (47%), Gaps = 8/240 (3%)
Query: 24 NSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD-AL 82
N L LP L L ++TLD+ N++T + + LE L V+ N++ + +D +
Sbjct: 168 NRLAHLPDS-LSCLSRLRTLDVDHNQLTAFPRQ-LLQLVALEELDVSSNRLRGLPEDISA 225
Query: 83 PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNE 142
+ LK + L +L TL +L LE + ++ N L+++ + +++++++ + N
Sbjct: 226 LRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSC-LQRLKMLNLSSNL 284
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
+ P+ L + L+ LY N + S+ + L+ + L N+I +L D E
Sbjct: 285 FEEFPAALLPLAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYL-PDSIVELTG 343
Query: 203 LAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE-IKGLRRLSVI--DLSHNQ 259
L EL + N++ L L + + N + + + +KG+ ++ +L+H+Q
Sbjct: 344 LEELVLQGNQIAVLPDHFGQLSRVGLWKIKDNPLIQPPYEVCMKGIPYIAAYQKELAHSQ 403
Score = 58.0 bits (134), Expect = 8e-08
Identities = 45/158 (28%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 105 DLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYG 163
+L D+E + + N L+ + L + ++++ N LP + +L L L
Sbjct: 61 NLGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSH 120
Query: 164 NNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRS 222
N + +L E + R L ++ LS N++ L A L ELD+++N L +L SL
Sbjct: 121 NRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAH-LEELDVSFNRLAHLPDSLSC 179
Query: 223 LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L LR L++ HN +T F Q ++ L L +D+S N++
Sbjct: 180 LSRLRTLDVDHNQLTAFPRQLLQ-LVALEELDVSSNRL 216
>AF061444-1|AAC77911.1| 907|Homo sapiens G protein-coupled receptor
LGR5 protein.
Length = 907
Score = 79.4 bits (187), Expect = 3e-14
Identities = 68/288 (23%), Positives = 129/288 (44%), Gaps = 9/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ + FT L + L +N L +P LQ+L +++L L N I+ + F + L
Sbjct: 105 IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSL 164
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
HL + DN ++EI A L+ + L +NK++ + + A +L + ++ N + S
Sbjct: 165 RHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHS 224
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ + ++ + +N L P+ ++ + +L+ L F+ NNI+S+ E + +L+
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLI 284
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS 240
I N I+F+ + F +L L + L +L L LT ++
Sbjct: 285 TIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLP 344
Query: 241 LQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIF 288
L L V+DLS+N + L V ++ ++ L HN I+
Sbjct: 345 QTVCNQLPNLQVLDLSYNLLEDLPS-----FSVCQKLQKIDLRHNEIY 387
Score = 63.3 bits (147), Expect = 2e-09
Identities = 65/274 (23%), Positives = 119/274 (43%), Gaps = 9/274 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ LA N+L +P+ L +K L L N++ + E ++++ L+ L + N
Sbjct: 89 LHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDAN 148
Query: 73 QISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTK 129
IS + L+H+ L N L + A R L L+ + + N + I +
Sbjct: 149 HISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGN 208
Query: 130 AKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNK 188
++H +N + SL + SL++L NN+ ++ NL +G N
Sbjct: 209 LSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNN 268
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLT-HNYMTEFSLQEIKG 246
I + + F L + N ++++ S + L LR L L + +TEF ++ G
Sbjct: 269 IRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEF--PDLTG 326
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
L + L+ QIS L ++ N + +VL+L
Sbjct: 327 TANLESLTLTGAQISSLPQTVCNQLP-NLQVLDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 69/281 (24%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F L ++ L N+L E P ++ L ++K L N I + E+ F L
Sbjct: 225 LGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHSNNIRSIPEKAFVGNPSL 283
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALR-----DLD---DLEWIFINA 116
+ DN I + + A HL + TLNGA + DL +LE + +
Sbjct: 284 ITIHFYDNPIQFVGRSAFQ------HLPELRTLTLNGASQITEFPDLTGTANLESLTLTG 337
Query: 117 NNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQK 175
+ S+ + + +Q++ ++N L+ LPS + LQ + N I + +T Q+
Sbjct: 338 AQISSLPQTVCNQLPNLQVLDLSYNLLEDLPS-FSVCQKLQKIDLRHNEIYEIKVDTFQQ 396
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+L + L++NKI + + F+ L +LD++ N L + + L L +L LT N+
Sbjct: 397 LLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLS--SFPITGLHGLTHLKLTGNH 454
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETR 276
+ SL + L VI++ + G EN + +
Sbjct: 455 ALQ-SLISSENFPELKVIEMPYAYQCCAFGVCENAYKISNQ 494
Score = 46.0 bits (104), Expect = 4e-04
Identities = 58/224 (25%), Positives = 90/224 (40%), Gaps = 13/224 (5%)
Query: 206 LDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL- 263
LD++ N + + L L SL L L L N +T GL L V+ L +NQ+ +
Sbjct: 71 LDLSMNNISQLLPNPLPSLHFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 130
Query: 264 TGSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXX 322
T +L+NL +++ LRLD NHI + + +I
Sbjct: 131 TEALQNLRSLQS----LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLS 186
Query: 323 XXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
++ N I + + + L S L H+N I L K F GL SL + DL++N +
Sbjct: 187 ALQAMTLALNKIHHIPDYAFGNLSSWVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246
Query: 382 HTVNYDLVSKSRCT-----INGVPSILKIYLQDNPVLCDDHLYE 420
+ + S N + SI + NP L H Y+
Sbjct: 247 DEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYD 290
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 78.6 bits (185), Expect = 5e-14
Identities = 77/301 (25%), Positives = 149/301 (49%), Gaps = 28/301 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V+ KL ++D +A N L L VL + H+K +DL N + + E+ + + H+
Sbjct: 386 VYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVD 445
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLN--TLNG-ALRDL----------------DDL 109
+ DN++++++ +L L+ +H G N+L TL+G +LR L L
Sbjct: 446 LRDNRLTDLDLSSLCS-LEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLL 504
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+ + + +AKK++++ ++N L +P + SL+ L N++++L
Sbjct: 505 TFLDLSRNLLECVP-DWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNL 563
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL---RSLKSL 226
TL + L + L N + L F++A L L+ + N L+ L + SL L
Sbjct: 564 P-TLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSML 622
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNH 286
+ L LT+N +T+ + + G L ++ L++NQ+ S N ++ ++ EL L N
Sbjct: 623 QLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLE---QLEELNLSGNK 679
Query: 287 I 287
+
Sbjct: 680 L 680
Score = 53.2 bits (122), Expect = 2e-06
Identities = 55/232 (23%), Positives = 103/232 (44%), Gaps = 13/232 (5%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK----DALPK--GLKHVHLGI 93
+ T+DL + ++ E F Q++ +L + N ++E+ D L K LK ++L
Sbjct: 251 ISTVDLSCYSLEEVPEHLFYS-QDITYLNLRHN-FMQLERPGGLDTLYKFSQLKGLNLSH 308
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLM 153
NKL L ++ L + ++ N + +++ +Q + N L +LP +L +
Sbjct: 309 NKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLN-LQTLCLDGNFLTTLPEELGNL 367
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L SL NN + E +K L R+ ++ N +E L + +D+ N L
Sbjct: 368 QQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHL 427
Query: 214 K-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
K + +L K + +++L N +T+ L + L +L NQ+ LT
Sbjct: 428 KTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQL---HCGRNQLRELT 476
Score = 40.7 bits (91), Expect = 0.013
Identities = 44/196 (22%), Positives = 90/196 (45%), Gaps = 9/196 (4%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L N + LP +++H+P ++ LDL N +T+L + F L +L + N + +
Sbjct: 555 LGHNHVQNLPT-LVEHIP-LEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSA 612
Query: 81 ALPKG----LKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
+ L+ ++L N L + L L + + N L++ K ++++
Sbjct: 613 CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEE 672
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
++ + N+L+++P+ + L +L + NNI E LQ + + + LS N + +
Sbjct: 673 LNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPEILQLPQ-IQFVDLSCNDLTEILIP 731
Query: 196 DFTEAEKLAELDIAYN 211
+ A L +LD+ N
Sbjct: 732 EALPA-TLQDLDLTGN 746
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 78.6 bits (185), Expect = 5e-14
Identities = 90/413 (21%), Positives = 172/413 (41%), Gaps = 20/413 (4%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK-DALPKGLKHVHLGINKLNTL 99
++L+L NK++++ F D+ L+ + + +N+++ + A + + L NK+ ++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 100 NGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSL 156
G+ L+ LE + ++ NN+ + N ++ ++ A N + +L L SL
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 157 QSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL-KY 215
+L N I L K L ++ L+ N+I + F L L + N + K
Sbjct: 191 LTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+G+ L + L+L +N + E + + GL L + LS+N I+ + +
Sbjct: 251 TDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQ--- 307
Query: 276 RVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHI 334
++ EL L N++ I I + +N I
Sbjct: 308 KLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Query: 335 T-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
+ T+E+TS F L SL +L N I +V + F GL L +L N I +V +D
Sbjct: 368 SGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFV 427
Query: 391 KSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQT 443
K + ++ ++++ + LCD L L + +TC P++
Sbjct: 428 KMK-------NLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPES 473
Score = 78.2 bits (184), Expect = 7e-14
Identities = 66/255 (25%), Positives = 126/255 (49%), Gaps = 11/255 (4%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI-QELEHLLVADNQI 74
++ L+ N++ E+ H P +K L+L N+I L F + + L L ++ N+I
Sbjct: 141 LEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRI 200
Query: 75 SEIEKDA--LPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAK 131
+++ A LP+ L + L N++ + G + L+ LE + + NN+ + +
Sbjct: 201 TQLPVRAFKLPR-LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLS 259
Query: 132 KMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKI 189
KM ++H +N L + S L + +L L+ N+I + + + L + LSFN +
Sbjct: 260 KMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNL 319
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIK 245
L ++ E L+ L +++N + ++ G+ + L+SLR L+L HN ++ E +
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFS 379
Query: 246 GLRRLSVIDLSHNQI 260
GL LS + L N+I
Sbjct: 380 GLDSLSKLTLFGNKI 394
Score = 77.8 bits (183), Expect = 9e-14
Identities = 65/247 (26%), Positives = 115/247 (46%), Gaps = 6/247 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK- 79
L N + + L+ ++ LDL N IT++ F ++ L +A N+I +E
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 80 --DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L + L + L N++ L L L + +N N ++ IE ++++
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKD 195
N + L + + L+ N++ ++ +L L ++ LS N I + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 196 DFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
++ +KL EL +++N L L+ SL L SL L L+HN ++ + KGLR L V+D
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 255 LSHNQIS 261
L HN+IS
Sbjct: 362 LDHNEIS 368
Score = 76.6 bits (180), Expect = 2e-13
Identities = 85/338 (25%), Positives = 145/338 (42%), Gaps = 16/338 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
LP + ++L NKL+ ++ A DL +L+ +++N N L ++ + L + + + H
Sbjct: 66 LPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQH 124
Query: 141 NELQSLP-SDLKLMPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFT 198
N+++S+ S LK SL+ L NNI + T + + L+ N+I L F
Sbjct: 125 NKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFD 184
Query: 199 EAEK-LAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
+ L L ++ N + L L L L+L N + +GL L V+ L
Sbjct: 185 GLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQR 244
Query: 258 NQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXX-XIQKIXX 315
N IS LT G+ L +++ L L++N + I +I
Sbjct: 245 NNISKLTDGAFWGL----SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSA 374
+S+N++T L+E S L SL L HN+I+ + + F GL SL
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
DL N+I + + +G+ S+ K+ L N +
Sbjct: 361 DLDHNEIS----GTIEDTSGAFSGLDSLSKLTLFGNKI 394
Score = 51.2 bits (117), Expect = 9e-06
Identities = 51/230 (22%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + L N + + Q L ++ L L RN I+KLT+ F + ++ L +
Sbjct: 209 KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 268
Query: 72 NQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N + E+ +L L +HL N + ++ L + ++ NNL ++ E
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIK-SLDET---LQKSRNLMRIG 183
+ + ++ +HN + + K + SL+ L N I ++++T +L ++
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLT 232
L NKI+ + K F+ E L L++ N ++ + + +K+L+ L+++
Sbjct: 389 LFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
Score = 50.4 bits (115), Expect = 2e-05
Identities = 68/293 (23%), Positives = 124/293 (42%), Gaps = 38/293 (12%)
Query: 119 LKSIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSR 177
L ++ +LP+ + + L ++N+L + P+ + +P+LQ +Y N + ++ S
Sbjct: 59 LAALPGDLPSWTRSLNL---SYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASS 115
Query: 178 NLMRIGLSFNKIEF----------------LTKDDFTEAEK--------LAELDIAYNEL 213
+++ + L NKI L+ ++ TE + EL++A N +
Sbjct: 116 HVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRI 175
Query: 214 KYLN-GSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENL 270
L G+ L +SL L L+ N +T+ ++ K L RL+ +DL+ N+I L+ G + + L
Sbjct: 176 GTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGL 234
Query: 271 VDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
+E L+L N+I + ++ +
Sbjct: 235 NSLEV----LKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHL 290
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
S N I + +F L EL+ NN+T LD++ L SL LS N I
Sbjct: 291 SNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Score = 39.9 bits (89), Expect = 0.023
Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED---FRDI 61
L E +L + L+ NS+ + + L ++ LDL N+I+ E+ F +
Sbjct: 322 LDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL 381
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANN 118
L L + N+I + K A +GL+H++LG N + ++ A + +L+ + I++++
Sbjct: 382 DSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDS 441
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 78.6 bits (185), Expect = 5e-14
Identities = 90/413 (21%), Positives = 172/413 (41%), Gaps = 20/413 (4%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK-DALPKGLKHVHLGINKLNTL 99
++L+L NK++++ F D+ L+ + + +N+++ + A + + L NK+ ++
Sbjct: 71 RSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 100 NGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSL 156
G+ L+ LE + ++ NN+ + N ++ ++ A N + +L L SL
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 157 QSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL-KY 215
+L N I L K L ++ L+ N+I + F L L + N + K
Sbjct: 191 LTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+G+ L + L+L +N + E + + GL L + LS+N I+ + +
Sbjct: 251 TDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQ--- 307
Query: 276 RVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHI 334
++ EL L N++ I I + +N I
Sbjct: 308 KLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEI 367
Query: 335 T-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
+ T+E+TS F L SL +L N I +V + F GL L +L N I +V +D
Sbjct: 368 SGTIEDTSGAFSGLDSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFV 427
Query: 391 KSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQT 443
K + ++ ++++ + LCD L L + +TC P++
Sbjct: 428 KMK-------NLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCAHPES 473
Score = 78.2 bits (184), Expect = 7e-14
Identities = 66/255 (25%), Positives = 126/255 (49%), Gaps = 11/255 (4%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI-QELEHLLVADNQI 74
++ L+ N++ E+ H P +K L+L N+I L F + + L L ++ N+I
Sbjct: 141 LEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRI 200
Query: 75 SEIEKDA--LPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAK 131
+++ A LP+ L + L N++ + G + L+ LE + + NN+ + +
Sbjct: 201 TQLPVRAFKLPR-LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLS 259
Query: 132 KMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKI 189
KM ++H +N L + S L + +L L+ N+I + + + L + LSFN +
Sbjct: 260 KMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNL 319
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT---EFSLQEIK 245
L ++ E L+ L +++N + ++ G+ + L+SLR L+L HN ++ E +
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFS 379
Query: 246 GLRRLSVIDLSHNQI 260
GL LS + L N+I
Sbjct: 380 GLDSLSKLTLFGNKI 394
Score = 77.8 bits (183), Expect = 9e-14
Identities = 65/247 (26%), Positives = 115/247 (46%), Gaps = 6/247 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK- 79
L N + + L+ ++ LDL N IT++ F ++ L +A N+I +E
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 80 --DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L + L + L N++ L L L + +N N ++ IE ++++
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKD 195
N + L + + L+ N++ ++ +L L ++ LS N I + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 196 DFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
++ +KL EL +++N L L+ SL L SL L L+HN ++ + KGLR L V+D
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 255 LSHNQIS 261
L HN+IS
Sbjct: 362 LDHNEIS 368
Score = 76.6 bits (180), Expect = 2e-13
Identities = 85/338 (25%), Positives = 145/338 (42%), Gaps = 16/338 (4%)
Query: 82 LPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
LP + ++L NKL+ ++ A DL +L+ +++N N L ++ + L + + + H
Sbjct: 66 LPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQH 124
Query: 141 NELQSLP-SDLKLMPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFT 198
N+++S+ S LK SL+ L NNI + T + + L+ N+I L F
Sbjct: 125 NKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFD 184
Query: 199 EAEK-LAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
+ L L ++ N + L L L L+L N + +GL L V+ L
Sbjct: 185 GLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQR 244
Query: 258 NQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXX-XIQKIXX 315
N IS LT G+ L +++ L L++N + I +I
Sbjct: 245 NNISKLTDGAFWGL----SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSA 374
+S+N++T L+E S L SL L HN+I+ + + F GL SL
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 375 DLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPV 412
DL N+I + + +G+ S+ K+ L N +
Sbjct: 361 DLDHNEIS----GTIEDTSGAFSGLDSLSKLTLFGNKI 394
Score = 51.2 bits (117), Expect = 9e-06
Identities = 51/230 (22%), Positives = 105/230 (45%), Gaps = 9/230 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + L N + + Q L ++ L L RN I+KLT+ F + ++ L +
Sbjct: 209 KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 268
Query: 72 NQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N + E+ +L L +HL N + ++ L + ++ NNL ++ E
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIK-SLDET---LQKSRNLMRIG 183
+ + ++ +HN + + K + SL+ L N I ++++T +L ++
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLT 388
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLT 232
L NKI+ + K F+ E L L++ N ++ + + +K+L+ L+++
Sbjct: 389 LFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHIS 438
Score = 50.4 bits (115), Expect = 2e-05
Identities = 68/293 (23%), Positives = 124/293 (42%), Gaps = 38/293 (12%)
Query: 119 LKSIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSR 177
L ++ +LP+ + + L ++N+L + P+ + +P+LQ +Y N + ++ S
Sbjct: 59 LAALPGDLPSWTRSLNL---SYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASS 115
Query: 178 NLMRIGLSFNKIEF----------------LTKDDFTEAEK--------LAELDIAYNEL 213
+++ + L NKI L+ ++ TE + EL++A N +
Sbjct: 116 HVVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRI 175
Query: 214 KYLN-GSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENL 270
L G+ L +SL L L+ N +T+ ++ K L RL+ +DL+ N+I L+ G + + L
Sbjct: 176 GTLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGL 234
Query: 271 VDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
+E L+L N+I + ++ +
Sbjct: 235 NSLEV----LKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHL 290
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
S N I + +F L EL+ NN+T LD++ L SL LS N I
Sbjct: 291 SNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Score = 39.9 bits (89), Expect = 0.023
Identities = 29/120 (24%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED---FRDI 61
L E +L + L+ NS+ + + L ++ LDL N+I+ E+ F +
Sbjct: 322 LDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL 381
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANN 118
L L + N+I + K A +GL+H++LG N + ++ A + +L+ + I++++
Sbjct: 382 DSLSKLTLFGNKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHISSDS 441
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 78.2 bits (184), Expect = 7e-14
Identities = 77/301 (25%), Positives = 149/301 (49%), Gaps = 28/301 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V+ KL ++D +A N L L VL + H+K +DL N + + E+ + + H+
Sbjct: 124 VYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVD 183
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLN--TLNG-ALRDL----------------DDL 109
+ DN++++++ +L L+ +H G N+L TL+G +LR L L
Sbjct: 184 LRDNRLTDLDLSSLCS-LEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLL 242
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+ + + +AKK++++ ++N L +P + SL+ L N++++L
Sbjct: 243 TFLDLSRNLLECVP-DWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNL 301
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL---RSLKSL 226
TL + L + L N + L F++A L L+ + N L+ L + SL L
Sbjct: 302 P-TLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSML 360
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNH 286
+ L LT+N +T+ + + G L ++ L++NQ+ S N ++ ++ EL L N
Sbjct: 361 QLLYLTNNLLTDQCIPVLVGHLHLRILRLANNQLQTFPASKLNKLE---QLEELNLSGNK 417
Query: 287 I 287
+
Sbjct: 418 L 418
Score = 51.6 bits (118), Expect = 7e-06
Identities = 43/180 (23%), Positives = 79/180 (43%), Gaps = 5/180 (2%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
LK ++L NKL L ++ L + ++ N + +++ +Q + N L +
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLN-LQTLCLDGNFLTT 97
Query: 146 LPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
LP +L + L SL NN + E +K L R+ ++ N +E L +
Sbjct: 98 LPEELGNLQQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKH 157
Query: 206 LDIAYNELK-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
+D+ N LK + +L K + +++L N +T+ L + L +L NQ+ LT
Sbjct: 158 VDLRMNHLKTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQL---HCGRNQLRELT 214
Score = 39.5 bits (88), Expect = 0.031
Identities = 42/164 (25%), Positives = 75/164 (45%), Gaps = 6/164 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVL--QHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
L +++F+K + Y + + NSL LP + L ++ L L N +T
Sbjct: 323 LPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPVLVGHL 382
Query: 63 ELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L L +A+NQ+ L K L+ ++L NKL T+ + + L + ++NN+
Sbjct: 383 HLRILRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNI- 441
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
SI E+ + ++Q + + N+L + L +LQ L GN
Sbjct: 442 SIFPEI-LQLPQIQFVDLSCNDLTEILIPEALPATLQDLDLTGN 484
>BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein.
Length = 1070
Score = 77.8 bits (183), Expect = 9e-14
Identities = 65/247 (26%), Positives = 115/247 (46%), Gaps = 6/247 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK- 79
L N + + L+ ++ LDL N IT++ F ++ L +A N+I +E
Sbjct: 122 LQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELG 181
Query: 80 --DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
D L + L + L N++ L L L + +N N ++ IE ++++
Sbjct: 182 AFDGLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLK 241
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKD 195
N + L + + L+ N++ ++ +L L ++ LS N I + +
Sbjct: 242 LQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRK 301
Query: 196 DFTEAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
++ +KL EL +++N L L+ SL L SL L L+HN ++ + KGLR L V+D
Sbjct: 302 GWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLD 361
Query: 255 LSHNQIS 261
L HN+IS
Sbjct: 362 LDHNEIS 368
Score = 74.9 bits (176), Expect = 7e-13
Identities = 58/226 (25%), Positives = 113/226 (50%), Gaps = 8/226 (3%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI-QELEHLLVADNQI 74
++ L+ N++ E+ H P +K L+L N+I L F + + L L ++ N+I
Sbjct: 141 LEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSLLTLRLSKNRI 200
Query: 75 SEIEKDA--LPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAK 131
+++ A LP+ L + L N++ + G + L+ LE + + NN+ + +
Sbjct: 201 TQLPVRAFKLPR-LTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLS 259
Query: 132 KMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKI 189
KM ++H +N L + S L + +L L+ N+I + + + L + LSFN +
Sbjct: 260 KMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNL 319
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
L ++ E L+ L +++N + ++ G+ + L+SLR L+L HN
Sbjct: 320 TRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHN 365
Score = 73.7 bits (173), Expect = 2e-12
Identities = 79/307 (25%), Positives = 132/307 (42%), Gaps = 12/307 (3%)
Query: 82 LPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
LP + ++L NK + ++ A DL +L+ +++N N L ++ + L + + + H
Sbjct: 66 LPSWTRSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPS-LGAASSHVVSLFLQH 124
Query: 141 NELQSLP-SDLKLMPSLQSLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFT 198
N+++S+ S LK SL+ L NNI + T + + L+ N+I L F
Sbjct: 125 NKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFD 184
Query: 199 EAEK-LAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
+ L L ++ N + L L L L+L N + +GL L V+ L
Sbjct: 185 GLSRSLLTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQR 244
Query: 258 NQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXX-XIQKIXX 315
N IS LT G+ L +++ L L++N + I +I
Sbjct: 245 NNISKLTDGAFWGL----SKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIARIHR 300
Query: 316 XXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSA 374
+S+N++T L+E S L SL L HN+I+ + + F GL SL
Sbjct: 301 KGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVL 360
Query: 375 DLSFNKI 381
DL N+I
Sbjct: 361 DLDHNEI 367
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/226 (23%), Positives = 104/226 (46%), Gaps = 5/226 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK-DALPKGLKHVHLGINKLNTL 99
++L+L NK +++ F D+ L+ + + +N+++ + A + + L NK+ ++
Sbjct: 71 RSLNLSYNKFSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLQHNKIRSV 130
Query: 100 NGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSL 156
G+ L+ LE + ++ NN+ + N ++ ++ A N + +L L SL
Sbjct: 131 EGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFDGLSRSL 190
Query: 157 QSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL-KY 215
+L N I L K L ++ L+ N+I + F L L + N + K
Sbjct: 191 LTLRLSKNRITQLPVRAFKLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKL 250
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
+G+ L + L+L +N + E + + GL L + LS+N I+
Sbjct: 251 TDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSIA 296
Score = 50.8 bits (116), Expect = 1e-05
Identities = 67/292 (22%), Positives = 122/292 (41%), Gaps = 36/292 (12%)
Query: 119 LKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
L ++ +LP+ + + L + +E+ P+ + +P+LQ +Y N + ++ S +
Sbjct: 59 LAALPGDLPSWTRSLNLSYNKFSEID--PAGFEDLPNLQEVYLNNNELTAVPSLGAASSH 116
Query: 179 LMRIGLSFNKIEF----------------LTKDDFTEAEK--------LAELDIAYNELK 214
++ + L NKI L+ ++ TE + EL++A N +
Sbjct: 117 VVSLFLQHNKIRSVEGSQLKAYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIG 176
Query: 215 YLN-GSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLV 271
L G+ L +SL L L+ N +T+ ++ K L RL+ +DL+ N+I L+ G + + L
Sbjct: 177 TLELGAFDGLSRSLLTLRLSKNRITQLPVRAFK-LPRLTQLDLNRNRIRLIEGLTFQGLN 235
Query: 272 DVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVS 330
+E L+L N+I + ++ +S
Sbjct: 236 SLEV----LKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLS 291
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
N I + +F L EL+ NN+T LD++ L SL LS N I
Sbjct: 292 NNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSI 343
Score = 39.9 bits (89), Expect = 0.023
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL + L N + + Q L ++ L L RN I+KLT+ F + ++ L +
Sbjct: 209 KLPRLTQLDLNRNRIRLIEGLTFQGLNSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEY 268
Query: 72 NQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPT 128
N + E+ +L L +HL N + ++ L + ++ NNL ++ E
Sbjct: 269 NSLVEVNSGSLYGLTALHQLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLA 328
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
+ + ++ +HN + + K + SL+ L N I E
Sbjct: 329 ELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIE 372
Score = 33.1 bits (72), Expect = 2.7
Identities = 31/139 (22%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED---FRDI 61
L E +L + L+ NS+ + + L ++ LDL N+I+ E+ F +
Sbjct: 322 LDEESLAELSSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL 381
Query: 62 QELEHLLVAD-NQISEIEKDALP-KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANN 118
L LL+ + +Q + + P L NK+ ++ A L+ LE + + N
Sbjct: 382 DSLSKLLLLEPSQSAGCSSPSQPHMSAGGRTLFGNKIKSVAKRAFSGLEGLEHLNLGGNA 441
Query: 119 LKSIENELPTKAKKMQLIH 137
++S++ + K K ++ +H
Sbjct: 442 IRSVQFDAFVKMKNLKELH 460
Score = 31.5 bits (68), Expect = 8.2
Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHL 91
NKI + + F ++ LEHL + N I ++ DA K LK +H+
Sbjct: 416 NKIKSVAKRAFSGLEGLEHLNLGGNAIRSVQFDAFVKMKNLKELHI 461
>Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V
precursor protein.
Length = 560
Score = 77.4 bits (182), Expect = 1e-13
Identities = 72/288 (25%), Positives = 132/288 (45%), Gaps = 10/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ +++F KL + +L N L LP + +L ++K LDL N +T L + +L
Sbjct: 137 IDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKL 196
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
E LL+ N++ ++ L L + N + ++ GA L +L + ++ N+L
Sbjct: 197 ERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAF 256
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ + L + + L+ N L LP L M LQ L+ +++L ++ + +
Sbjct: 257 LPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Query: 181 R-IGLSFN-KIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
R +G++ + ++ L + F +L L + N L L +G LR L LR ++L N +
Sbjct: 317 RYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLR 376
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ L L + L HNQ+ L G + + R+ E+ L HN
Sbjct: 377 ALPRALFRNLSSLESVQLDHNQLETLPGDVFGAL---PRLTEVLLGHN 421
Score = 73.7 bits (173), Expect = 2e-12
Identities = 73/283 (25%), Positives = 128/283 (45%), Gaps = 8/283 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ F+ + ++ ++D+ + + L +KTL L RNKIT L +
Sbjct: 64 VLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVL 123
Query: 64 LEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
LE L + N + I+++ K L+ + L N+L+ L +L +L++L+ + ++ NNL
Sbjct: 124 LEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLT 183
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSRN 178
+ L K++ + N L SL S L + +L L F+ N+I+S+ + N
Sbjct: 184 HLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPN 243
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMT 237
L + LS N + FL F + L L + N L L G L + L+ L L +
Sbjct: 244 LSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLR 303
Query: 238 EFSLQEIKGLRRLSV--IDLSHNQISLLTGSLENLVDVETRVL 278
+ L RL + LS +L G+ + L +++ L
Sbjct: 304 TLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
>L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane
glycoprotein V protein.
Length = 560
Score = 77.4 bits (182), Expect = 1e-13
Identities = 72/288 (25%), Positives = 132/288 (45%), Gaps = 10/288 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ +++F KL + +L N L LP + +L ++K LDL N +T L + +L
Sbjct: 137 IDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKL 196
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
E LL+ N++ ++ L L + N + ++ GA L +L + ++ N+L
Sbjct: 197 ERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAF 256
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ + L + + L+ N L LP L M LQ L+ +++L ++ + +
Sbjct: 257 LPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Query: 181 R-IGLSFN-KIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
R +G++ + ++ L + F +L L + N L L +G LR L LR ++L N +
Sbjct: 317 RYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLR 376
Query: 238 EFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ L L + L HNQ+ L G + + R+ E+ L HN
Sbjct: 377 ALPRALFRNLSSLESVQLDHNQLETLPGDVFGAL---PRLTEVLLGHN 421
Score = 73.7 bits (173), Expect = 2e-12
Identities = 73/283 (25%), Positives = 128/283 (45%), Gaps = 8/283 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ F+ + ++ ++D+ + + L +KTL L RNKIT L +
Sbjct: 64 VLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVL 123
Query: 64 LEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
LE L + N + I+++ K L+ + L N+L+ L +L +L++L+ + ++ NNL
Sbjct: 124 LEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLT 183
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSRN 178
+ L K++ + N L SL S L + +L L F+ N+I+S+ + N
Sbjct: 184 HLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPN 243
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMT 237
L + LS N + FL F + L L + N L L G L + L+ L L +
Sbjct: 244 LSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLR 303
Query: 238 EFSLQEIKGLRRLSV--IDLSHNQISLLTGSLENLVDVETRVL 278
+ L RL + LS +L G+ + L +++ L
Sbjct: 304 TLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLAL 346
>AY358312-1|AAQ88679.1| 716|Homo sapiens NLRR protein.
Length = 716
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/274 (28%), Positives = 127/274 (46%), Gaps = 12/274 (4%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+ N+ + L +L + TL L N+IT++T+ +D+ L+ L + NQIS I A
Sbjct: 103 SQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHA 162
Query: 82 LP--KGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
K L +HL NKL ++ D +LE + I N + I + ++ +
Sbjct: 163 FAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVL 222
Query: 139 AHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD 196
A L +P + L + SL+SL FY N + + + LQK NL + L+ N I + + D
Sbjct: 223 AGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGD 282
Query: 197 FTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN----YMTEFSLQEIKGLRRL 250
F +L EL I EL ++ +L +L L L T+N Y+ + + + L L
Sbjct: 283 FKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESL 342
Query: 251 SVIDLSHNQISLLT-GSLENLVDVETRVLELRLD 283
+ + + N I T SL NL ++ LR D
Sbjct: 343 MLNNNALNAIYQKTVESLPNLREISIHSNPLRCD 376
Score = 53.6 bits (123), Expect = 2e-06
Identities = 39/137 (28%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD- 71
LD ++ S DN L ++P+ LQ +P++K LDL +N I K+ E DF+++ L+ L + +
Sbjct: 238 LDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNM 297
Query: 72 NQISEIEK---DALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELP 127
++ +++ D LP+ K KL+ ++ A R + LE + +N N L +I +
Sbjct: 298 GELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTV 357
Query: 128 TKAKKMQLIHAAHNELQ 144
++ I N L+
Sbjct: 358 ESLPNLREISIHSNPLR 374
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 3/122 (2%)
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L +PS+L Q L NNI + LQ+ NL + S N + + +
Sbjct: 63 LTRIPSNLS--SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ 120
Query: 203 LAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N++ + L+ L +L+ L + HN ++ S GL+ L + L+ N++
Sbjct: 121 LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK 180
Query: 262 LL 263
++
Sbjct: 181 VI 182
Score = 36.7 bits (81), Expect = 0.22
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 19/170 (11%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
LA L ++P + L L +++L NK+ K+ + + + L+ L + N I +I++
Sbjct: 222 LAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEG 281
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
L+ LGIN + G L +D + N L +E T K+ IH
Sbjct: 282 DFKNMLRLKELGINNM----GELVSVD--RYALDNLPELTKLE---ATNNPKLSYIHRL- 331
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+ +P+L+SL N + ++ +T++ NL I + N +
Sbjct: 332 --------AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
Score = 31.9 bits (69), Expect = 6.2
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N IT + + L +L+EL +HN I T+ F GL +L L+ NK+ ++
Sbjct: 129 NQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVID----- 183
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
SR + P++ + + +NPV+
Sbjct: 184 -SR-WFDSTPNLEILMIGENPVI 204
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 77.4 bits (182), Expect = 1e-13
Identities = 65/244 (26%), Positives = 118/244 (48%), Gaps = 6/244 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 81 ALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
AL + L+ + L NKL A+R L L+ + + NN+K+I + +Q IH
Sbjct: 90 ALWELPSLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHF 149
Query: 139 AHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDD 196
N +Q + S + +P L +L G +I+ + L+ + +L + L+ I L
Sbjct: 150 YDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSLEILTLTRAGIRLLPSGM 208
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ +L L++++N+++ L SL + L + L HN + E L L +DLS
Sbjct: 209 CQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS 267
Query: 257 HNQI 260
N I
Sbjct: 268 WNAI 271
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/249 (25%), Positives = 120/249 (48%), Gaps = 10/249 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++LDL NK+ + R + L+ L
Sbjct: 67 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVA-IRTLGRLQELGF 125
Query: 70 ADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLKSIENE 125
+N I I + A L+ +H N + + A + L L + +N A +++ +
Sbjct: 126 HNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDL 185
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L IGL
Sbjct: 186 KGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGL 242
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQE 243
N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T L
Sbjct: 243 QHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAG 302
Query: 244 IKGLRRLSV 252
+ GL L +
Sbjct: 303 LGGLMHLKL 311
Score = 64.5 bits (150), Expect = 9e-10
Identities = 60/205 (29%), Positives = 92/205 (44%), Gaps = 7/205 (3%)
Query: 86 LKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ + L N L+ + G A L L+ + + N L I E + +Q + +N+LQ
Sbjct: 49 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQ 108
Query: 145 SLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEKL 203
P ++ + LQ L F+ NNIK++ E L++ I N I+F+ + F KL
Sbjct: 109 EFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKL 168
Query: 204 AELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
L + L+ SL L LT + + L RL V++LSHNQI L
Sbjct: 169 HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL 228
Query: 264 TGSLENLVDVETRVLELRLDHNHIF 288
SL +E E+ L HN I+
Sbjct: 229 P-SLHRCQKLE----EIGLQHNRIW 248
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 77.4 bits (182), Expect = 1e-13
Identities = 65/244 (26%), Positives = 118/244 (48%), Gaps = 6/244 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +
Sbjct: 30 LSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAE 89
Query: 81 ALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
AL + L+ + L NKL A+R L L+ + + NN+K+I + +Q IH
Sbjct: 90 ALWELPSLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHF 149
Query: 139 AHNELQSL-PSDLKLMPSLQSLYFYG-NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDD 196
N +Q + S + +P L +L G +I+ + L+ + +L + L+ I L
Sbjct: 150 YDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD-LKGTTSLEILTLTRAGIRLLPSGM 208
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
+ +L L++++N+++ L SL + L + L HN + E L L +DLS
Sbjct: 209 CQQLPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLS 267
Query: 257 HNQI 260
N I
Sbjct: 268 WNAI 271
Score = 69.7 bits (163), Expect = 3e-11
Identities = 64/249 (25%), Positives = 120/249 (48%), Gaps = 10/249 (4%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++LDL NK+ + R + L+ L
Sbjct: 67 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVA-IRTLGRLQELGF 125
Query: 70 ADNQISEIEKDALPKG--LKHVHLGINKLNTLN-GALRDLDDLEWIFIN-ANNLKSIENE 125
+N I I + A L+ +H N + + A + L L + +N A +++ +
Sbjct: 126 HNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDL 185
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + ++++ ++ LPS + + +P L+ L N I+ L +L + + L IGL
Sbjct: 186 KGTTS--LEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGL 242
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQE 243
N+I + D F++ L LD+++N ++ ++ + +L SL L+LT N +T L
Sbjct: 243 QHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAG 302
Query: 244 IKGLRRLSV 252
+ GL L +
Sbjct: 303 LGGLMHLKL 311
Score = 64.5 bits (150), Expect = 9e-10
Identities = 60/205 (29%), Positives = 92/205 (44%), Gaps = 7/205 (3%)
Query: 86 LKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ + L N L+ + G A L L+ + + N L I E + +Q + +N+LQ
Sbjct: 49 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQ 108
Query: 145 SLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEKL 203
P ++ + LQ L F+ NNIK++ E L++ I N I+F+ + F KL
Sbjct: 109 EFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKL 168
Query: 204 AELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
L + L+ SL L LT + + L RL V++LSHNQI L
Sbjct: 169 HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL 228
Query: 264 TGSLENLVDVETRVLELRLDHNHIF 288
SL +E E+ L HN I+
Sbjct: 229 P-SLHRCQKLE----EIGLQHNRIW 248
>AB074161-1|BAE45733.1| 716|Homo sapiens neuronal leucine-rich
repeat protein-1 protein.
Length = 716
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/274 (28%), Positives = 127/274 (46%), Gaps = 12/274 (4%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+ N+ + L +L + TL L N+IT++T+ +D+ L+ L + NQIS I A
Sbjct: 103 SQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHA 162
Query: 82 LP--KGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
K L +HL NKL ++ D +LE + I N + I + ++ +
Sbjct: 163 FAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVL 222
Query: 139 AHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD 196
A L +P + L + SL+SL FY N + + + LQK NL + L+ N I + + D
Sbjct: 223 AGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGD 282
Query: 197 FTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN----YMTEFSLQEIKGLRRL 250
F +L EL I EL ++ +L +L L L T+N Y+ + + + L L
Sbjct: 283 FKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESL 342
Query: 251 SVIDLSHNQISLLT-GSLENLVDVETRVLELRLD 283
+ + + N I T SL NL ++ LR D
Sbjct: 343 MLNNNALNAIYQKTVESLPNLREISIHSNPLRCD 376
Score = 53.6 bits (123), Expect = 2e-06
Identities = 39/137 (28%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD- 71
LD ++ S DN L ++P+ LQ +P++K LDL +N I K+ E DF+++ L+ L + +
Sbjct: 238 LDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNM 297
Query: 72 NQISEIEK---DALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELP 127
++ +++ D LP+ K KL+ ++ A R + LE + +N N L +I +
Sbjct: 298 GELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTV 357
Query: 128 TKAKKMQLIHAAHNELQ 144
++ I N L+
Sbjct: 358 ESLPNLREISIHSNPLR 374
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 3/122 (2%)
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L +PS+L Q L NNI + LQ+ NL + S N + + +
Sbjct: 63 LTRIPSNLS--SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ 120
Query: 203 LAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N++ + L+ L +L+ L + HN ++ S GL+ L + L+ N++
Sbjct: 121 LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK 180
Query: 262 LL 263
++
Sbjct: 181 VI 182
Score = 36.7 bits (81), Expect = 0.22
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 19/170 (11%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
LA L ++P + L L +++L NK+ K+ + + + L+ L + N I +I++
Sbjct: 222 LAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEG 281
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
L+ LGIN + G L +D + N L +E T K+ IH
Sbjct: 282 DFKNMLRLKELGINNM----GELVSVD--RYALDNLPELTKLE---ATNNPKLSYIHRL- 331
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+ +P+L+SL N + ++ +T++ NL I + N +
Sbjct: 332 --------AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
Score = 31.9 bits (69), Expect = 6.2
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N IT + + L +L+EL +HN I T+ F GL +L L+ NK+ ++
Sbjct: 129 NQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVID----- 183
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
SR + P++ + + +NPV+
Sbjct: 184 -SR-WFDSTPNLEILMIGENPVI 204
>AB040930-1|BAA96021.1| 730|Homo sapiens KIAA1497 protein protein.
Length = 730
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/274 (28%), Positives = 127/274 (46%), Gaps = 12/274 (4%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+ N+ + L +L + TL L N+IT++T+ +D+ L+ L + NQIS I A
Sbjct: 117 SQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHA 176
Query: 82 LP--KGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
K L +HL NKL ++ D +LE + I N + I + ++ +
Sbjct: 177 FAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVL 236
Query: 139 AHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD 196
A L +P + L + SL+SL FY N + + + LQK NL + L+ N I + + D
Sbjct: 237 AGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGD 296
Query: 197 FTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN----YMTEFSLQEIKGLRRL 250
F +L EL I EL ++ +L +L L L T+N Y+ + + + L L
Sbjct: 297 FKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESL 356
Query: 251 SVIDLSHNQISLLT-GSLENLVDVETRVLELRLD 283
+ + + N I T SL NL ++ LR D
Sbjct: 357 MLNNNALNAIYQKTVESLPNLREISIHSNPLRCD 390
Score = 53.6 bits (123), Expect = 2e-06
Identities = 39/137 (28%), Positives = 72/137 (52%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD- 71
LD ++ S DN L ++P+ LQ +P++K LDL +N I K+ E DF+++ L+ L + +
Sbjct: 252 LDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNM 311
Query: 72 NQISEIEK---DALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELP 127
++ +++ D LP+ K KL+ ++ A R + LE + +N N L +I +
Sbjct: 312 GELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTV 371
Query: 128 TKAKKMQLIHAAHNELQ 144
++ I N L+
Sbjct: 372 ESLPNLREISIHSNPLR 388
Score = 43.6 bits (98), Expect = 0.002
Identities = 30/122 (24%), Positives = 55/122 (45%), Gaps = 3/122 (2%)
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L +PS+L Q L NNI + LQ+ NL + S N + + +
Sbjct: 77 LTRIPSNLS--SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ 134
Query: 203 LAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N++ + L+ L +L+ L + HN ++ S GL+ L + L+ N++
Sbjct: 135 LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK 194
Query: 262 LL 263
++
Sbjct: 195 VI 196
Score = 36.7 bits (81), Expect = 0.22
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 19/170 (11%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
LA L ++P + L L +++L NK+ K+ + + + L+ L + N I +I++
Sbjct: 236 LAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPNLKFLDLNKNPIHKIQEG 295
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
L+ LGIN + G L +D + N L +E T K+ IH
Sbjct: 296 DFKNMLRLKELGINNM----GELVSVD--RYALDNLPELTKLE---ATNNPKLSYIHRL- 345
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+ +P+L+SL N + ++ +T++ NL I + N +
Sbjct: 346 --------AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 387
Score = 31.9 bits (69), Expect = 6.2
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N IT + + L +L+EL +HN I T+ F GL +L L+ NK+ ++
Sbjct: 143 NQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLKVID----- 197
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
SR + P++ + + +NPV+
Sbjct: 198 -SR-WFDSTPNLEILMIGENPVI 218
>J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA
encoding bone small proteoglycan I (biglycan), complete
cds. ).
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 44.8 bits (101), Expect = 8e-04
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 44.8 bits (101), Expect = 8e-04
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 44.8 bits (101), Expect = 8e-04
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein.
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 44.8 bits (101), Expect = 8e-04
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 44.8 bits (101), Expect = 8e-04
Identities = 49/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein
variant protein.
Length = 368
Score = 77.0 bits (181), Expect = 2e-13
Identities = 58/226 (25%), Positives = 109/226 (48%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F +++L+ L ++ N + EI +
Sbjct: 97 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPN 156
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 157 -LPSSLVELRIHDNRIRKVPEGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 215
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 216 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 273
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 274 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 319
Score = 72.9 bits (171), Expect = 3e-12
Identities = 60/241 (24%), Positives = 110/241 (45%), Gaps = 5/241 (2%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+D L +P+ + P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A
Sbjct: 77 SDLGLKSVPKEIS---PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKA 133
Query: 82 LPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHN 141
K L I+K + + L + I+ N ++ + + + + M I N
Sbjct: 134 FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPEGVFSGLRNMNCIEMGGN 193
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
L++ + L+ Y + K L + L NKI+ + +D
Sbjct: 194 PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYS 253
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
KL L + +N+++ + NGSL L +LR L+L +N + + L+ L V+ L N I
Sbjct: 254 KLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNI 312
Query: 261 S 261
+
Sbjct: 313 T 313
Score = 46.4 bits (105), Expect = 3e-04
Identities = 50/180 (27%), Positives = 87/180 (48%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + +K+Q ++ + N L +P +L SL L + N I+ + E
Sbjct: 120 VLVN-NKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPE 176
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 177 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 233
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 234 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 289
>BC045113-1|AAH45113.1| 522|Homo sapiens LRRTM1 protein protein.
Length = 522
Score = 76.6 bits (180), Expect = 2e-13
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 7/211 (3%)
Query: 85 GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
GL + L N L+ L G L L W++++ N++ S++ + K ++++ + + N++
Sbjct: 66 GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQI 125
Query: 144 QSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
LP + + MP+L+S+ N +++L + R L + + N I+F+ F +
Sbjct: 126 TQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCR 185
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L LDI YN+LK L S L L L+L HN + + + L L + L N++
Sbjct: 186 SLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKV 245
Query: 261 SLLTGSLE---NLVDVETRVLELRLDHNHIF 288
+++ SL+ NL ++ E+ H+F
Sbjct: 246 AIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF 276
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 27/236 (11%)
Query: 3 CVLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
C ++ F KL V +L+ N + +LP + +P+++++DL NK+ L + F ++
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLR 161
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
+L L + N I + + LK + +G N+L +L
Sbjct: 162 KLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSL--------------------- 200
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
N K +L H HN+L + + + SL SL N + + +L NL
Sbjct: 201 -ARNSFAGLFKLTEL-HLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNL 258
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ LS N+IE++ F L L + N L Y+ L S KSL + L N
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 37.5 bits (83), Expect = 0.12
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGLPSLCSADLSFNKIHTVNYD 387
+ +NHI +++ + L ++EL N IT L + F +P+L S DLS+NK+ + D
Sbjct: 96 LDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPD 155
Query: 388 L 388
L
Sbjct: 156 L 156
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 76.6 bits (180), Expect = 2e-13
Identities = 66/269 (24%), Positives = 123/269 (45%), Gaps = 6/269 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K +VF +L + L N + + L ++ LDL N++ L E+ F + L
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGL 292
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
L ++ N I+ + L+ + LG N++ L + L LE + ++ N L+
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQE 352
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNL 179
++ M +++ + N L++LP + + + L SL+ G+ + + T L
Sbjct: 353 VKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGL 412
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTE 238
R+ L N + + + +L ELD+ N+L +L L + L L YL L+ N + E
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 472
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+R +D+SHN++ L SL
Sbjct: 473 LPADALGPLQRAFWLDVSHNRLEALPNSL 501
Score = 71.7 bits (168), Expect = 6e-12
Identities = 68/247 (27%), Positives = 116/247 (46%), Gaps = 11/247 (4%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALR 104
N ++ + F+++ L L + Q+ +E AL + L H+HL N+L +L G
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 105 DLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYG 163
L + ++ N L +E+ L + ++ N L LP + + + SL+ L G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 164 NNIKSLDETLQKS-RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLR 221
N + L L L + LS N + + + F + +L +L + N + + G+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 222 SLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLEL 280
LK+LR+L+L+HN + GL L V+ LSHN I SL + ++L +E EL
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLE----EL 319
Query: 281 RLDHNHI 287
+L HN I
Sbjct: 320 QLGHNRI 326
Score = 66.5 bits (155), Expect = 2e-10
Identities = 63/265 (23%), Positives = 126/265 (47%), Gaps = 6/265 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ ++F+ L + L+ N+L + +V LP ++ L L RN I + F ++ L
Sbjct: 209 LQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKAL 268
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L ++ N+++ + +D P GL+ + L N + +L +DL LE + + N ++
Sbjct: 269 RWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 328
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ +++++ HN+LQ + + L + ++ + GN +++L E + + L
Sbjct: 329 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMAVMNLSGNCLRNLPEQVFRGLGKL 388
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTE 238
+ L + + + FT L L + N L + SL L L L+LT N +T
Sbjct: 389 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH 448
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ +GL +L + LS N+++ L
Sbjct: 449 LPHRLFQGLGKLEYLLLSRNRLAEL 473
Score = 60.9 bits (141), Expect = 1e-08
Identities = 69/253 (27%), Positives = 109/253 (43%), Gaps = 9/253 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E F L + L+ N++ L + L ++ L L N+I +L E F + +L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 65 EHLLVADNQISEIEKDALPKGLKH---VHLGINKLNTL-NGALRDLDDLEWIFINANNLK 120
E L + NQ+ E++ A GL + ++L N L L R L L + + + L
Sbjct: 341 EVLTLDHNQLQEVKAGAF-LGLTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLG 399
Query: 121 SIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRN 178
I T ++ + N L + L + L L N + L L Q
Sbjct: 400 RIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGK 459
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
L + LS N++ L D ++ LD+++N L+ L N L L LRYL+L +N +
Sbjct: 460 LEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Query: 238 EFSLQEIKGLRRL 250
F+ Q GL RL
Sbjct: 520 TFTPQP-PGLERL 531
Score = 60.1 bits (139), Expect = 2e-08
Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 11/307 (3%)
Query: 80 DALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
D +P G + + L N L+++ A ++L L ++ + L S+E + + + +H
Sbjct: 70 DGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHL 129
Query: 139 AHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDD 196
N+L+SL P+L SL N + L++ L + +L + L +N + L
Sbjct: 130 ERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAA 189
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L EL +A N L YL +L S L LR L+L+ N + L RL + L
Sbjct: 190 FRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYL 249
Query: 256 SHNQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKI 313
N I+ + G+ L + L L HN + I +
Sbjct: 250 DRNLIAAVAPGAFLGLKALRW----LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 305
Query: 314 XXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLC 372
+ +N I L E S L LE L HN + V F GL ++
Sbjct: 306 RPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNMA 365
Query: 373 SADLSFN 379
+LS N
Sbjct: 366 VMNLSGN 372
>AY358310-1|AAQ88677.1| 522|Homo sapiens DFLL675 protein.
Length = 522
Score = 76.6 bits (180), Expect = 2e-13
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 7/211 (3%)
Query: 85 GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
GL + L N L+ L G L L W++++ N++ S++ + K ++++ + + N++
Sbjct: 66 GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQI 125
Query: 144 QSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
LP + + MP+L+S+ N +++L + R L + + N I+F+ F +
Sbjct: 126 TQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCR 185
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L LDI YN+LK L S L L L+L HN + + + L L + L N++
Sbjct: 186 SLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKV 245
Query: 261 SLLTGSLE---NLVDVETRVLELRLDHNHIF 288
+++ SL+ NL ++ E+ H+F
Sbjct: 246 AIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF 276
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 27/236 (11%)
Query: 3 CVLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
C ++ F KL V +L+ N + +LP + +P+++++DL NK+ L + F ++
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLR 161
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
+L L + N I + + LK + +G N+L +L
Sbjct: 162 KLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSL--------------------- 200
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
N K +L H HN+L + + + SL SL N + + +L NL
Sbjct: 201 -ARNSFAGLFKLTEL-HLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNL 258
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ LS N+IE++ F L L + N L Y+ L S KSL + L N
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 37.5 bits (83), Expect = 0.12
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGLPSLCSADLSFNKIHTVNYD 387
+ +NHI +++ + L ++EL N IT L + F +P+L S DLS+NK+ + D
Sbjct: 96 LDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPD 155
Query: 388 L 388
L
Sbjct: 156 L 156
>AY182024-1|AAO67545.1| 522|Homo sapiens leucine-rich repeat
transmembrane neuronal 1 protein protein.
Length = 522
Score = 76.6 bits (180), Expect = 2e-13
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 7/211 (3%)
Query: 85 GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
GL + L N L+ L G L L W++++ N++ S++ + K ++++ + + N++
Sbjct: 66 GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQI 125
Query: 144 QSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
LP + + MP+L+S+ N +++L + R L + + N I+F+ F +
Sbjct: 126 TQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCR 185
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L LDI YN+LK L S L L L+L HN + + + L L + L N++
Sbjct: 186 SLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKV 245
Query: 261 SLLTGSLE---NLVDVETRVLELRLDHNHIF 288
+++ SL+ NL ++ E+ H+F
Sbjct: 246 AIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF 276
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 27/236 (11%)
Query: 3 CVLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
C ++ F KL V +L+ N + +LP + +P+++++DL NK+ L + F ++
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLR 161
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
+L L + N I + + LK + +G N+L +L
Sbjct: 162 KLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSL--------------------- 200
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
N K +L H HN+L + + + SL SL N + + +L NL
Sbjct: 201 -ARNSFAGLFKLTEL-HLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNL 258
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ LS N+IE++ F L L + N L Y+ L S KSL + L N
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 37.5 bits (83), Expect = 0.12
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGLPSLCSADLSFNKIHTVNYD 387
+ +NHI +++ + L ++EL N IT L + F +P+L S DLS+NK+ + D
Sbjct: 96 LDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPD 155
Query: 388 L 388
L
Sbjct: 156 L 156
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 68/270 (25%), Positives = 129/270 (47%), Gaps = 10/270 (3%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++D L N L E+P V+ L + TL L N+IT + E+D +++ +L L + +
Sbjct: 6 KLRMLD---LRHNKLREIPS-VVYRLDSLTTLYLRFNRITTV-EKDIKNLSKLSMLSIRE 60
Query: 72 NQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ + L + L N+L+ + +L LE + + NN+ ++ L +
Sbjct: 61 NKIKQLPAEIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSL 120
Query: 131 KKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNK 188
K+ + A N Q P ++ SL N I + + +++ L ++ + N+
Sbjct: 121 VKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQ 180
Query: 189 IEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR 248
+ L D F + EL++A N+L + + L SL L L++N + + + LR
Sbjct: 181 LTSLPLD-FGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP-HGLGNLR 238
Query: 249 RLSVIDLSHNQISLLTGSLENLVDVETRVL 278
+L +DL N++ L + L D++ VL
Sbjct: 239 KLRELDLEENKLESLPNEIAYLKDLQKLVL 268
Score = 63.7 bits (148), Expect = 2e-09
Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 3/203 (1%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L ES+ + L ++ +LA N P + +L++ N+I K+ F + L
Sbjct: 112 LPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVL 171
Query: 65 EHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
L + DNQ++ + D + ++L N+L + + L LE + ++ N LK +
Sbjct: 172 SKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLP 231
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG 183
+ L +K++ + N+L+SLP+++ + LQ L N + +L + NL +G
Sbjct: 232 HGLGN-LRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLG 290
Query: 184 LSFNKIEFLTKDDFTEAEKLAEL 206
L N + L ++ T E L EL
Sbjct: 291 LGENLLTHLPEEIGT-LENLEEL 312
Score = 62.1 bits (144), Expect = 5e-09
Identities = 57/255 (22%), Positives = 103/255 (40%), Gaps = 7/255 (2%)
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
KK++++ HN+L+ +PS + + SL +LY N I ++++ ++ L + + NKI+
Sbjct: 5 KKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIK 64
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
L + L+ L + YN L + SL +L LNL +N ++ + L +L
Sbjct: 65 QLPA-EIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKL 123
Query: 251 SVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXX 309
+ + L+ N L G + + L ++HN I
Sbjct: 124 NSLTLARNCFQLYPVGGPSQF----STIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDN 179
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLP 369
++ N +T + E + L SLE LI +N + L L
Sbjct: 180 QLTSLPLDFGTWTSMVELNLATNQLTKIPE-DVSGLVSLEVLILSNNLLKKLPHGLGNLR 238
Query: 370 SLCSADLSFNKIHTV 384
L DL NK+ ++
Sbjct: 239 KLRELDLEENKLESL 253
Score = 62.1 bits (144), Expect = 5e-09
Identities = 67/274 (24%), Positives = 120/274 (43%), Gaps = 12/274 (4%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E L + S+ +N + +LP + +L + L L N+++ + LE
Sbjct: 44 EKDIKNLSKLSMLSIRENKIKQLPAEI-GNLSSLSRLGLRYNRLSAIPRS-LAKCSALEE 101
Query: 67 LLVADNQISEIEKDALPKGLKHVHLGINKLNTLN----GALRDLDDLEWIFINANNLKSI 122
L + +N IS + + L +K L + + N G + + + N + I
Sbjct: 102 LNLENNNISTLPESLLSSLVKLNSLTLAR-NCFQLYPVGGPSQFSTIYSLNMEHNRINKI 160
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
+ ++AK + ++ N+L SLP D S+ L N + + E + +L +
Sbjct: 161 PFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVL 220
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
LS N ++ L KL ELD+ N+L+ L + LK L+ L LT+N +T +
Sbjct: 221 ILSNNLLKKLPHG-LGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLP-R 278
Query: 243 EIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
I L L+ + L N ++ L G+LENL ++
Sbjct: 279 GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEEL 312
Score = 52.4 bits (120), Expect = 4e-06
Identities = 40/132 (30%), Positives = 71/132 (53%), Gaps = 5/132 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L++N L +LP H L +L ++ LDL NK+ L E +++L+ L++ +NQ++ + +
Sbjct: 222 LSNNLLKKLP-HGLGNLRKLRELDLEENKLESLPNE-IAYLKDLQKLVLTNNQLTTLPRG 279
Query: 81 -ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINAN-NLKSIENELPTKAKKMQLIHA 138
L H+ LG N L L + L++LE +++N N NL S+ EL K+ ++
Sbjct: 280 IGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFEL-ALCSKLSIMSI 338
Query: 139 AHNELQSLPSDL 150
+ L LP +
Sbjct: 339 ENCPLSHLPPQI 350
Score = 47.6 bits (108), Expect = 1e-04
Identities = 42/169 (24%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
++ N + ++P + + L++ N++T L DF + L +A NQ+++I +
Sbjct: 151 NMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPL-DFGTWTSMVELNLATNQLTKIPE 209
Query: 80 DALPK-GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
D L+ + L N L L L +L L + + N L+S+ NE+ K +Q +
Sbjct: 210 DVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEI-AYLKDLQKLVL 268
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+N+L +LP + + +L L N + L E + NL + L+ N
Sbjct: 269 TNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 317
>AK056644-1|BAB71240.1| 522|Homo sapiens protein ( Homo sapiens
cDNA FLJ32082 fis, clone OCBBF2000231, weakly similar to
PHOSPHOLIPASE A2 INHIBITOR SUBUNIT B PRECURSOR. ).
Length = 522
Score = 76.6 bits (180), Expect = 2e-13
Identities = 55/211 (26%), Positives = 104/211 (49%), Gaps = 7/211 (3%)
Query: 85 GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
GL + L N L+ L G L L W++++ N++ S++ + K ++++ + + N++
Sbjct: 66 GLLGLSLRYNSLSELRAGQFTGLMQLTWLYLDHNHICSVQGDAFQKLRRVKELTLSSNQI 125
Query: 144 QSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
LP + + MP+L+S+ N +++L + R L + + N I+F+ F +
Sbjct: 126 TQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLRKLTTLHMRANAIQFVPVRIFQDCR 185
Query: 202 KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L LDI YN+LK L S L L L+L HN + + + L L + L N++
Sbjct: 186 SLKFLDIGYNQLKSLARNSFAGLFKLTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKV 245
Query: 261 SLLTGSLE---NLVDVETRVLELRLDHNHIF 288
+++ SL+ NL ++ E+ H+F
Sbjct: 246 AIVVSSLDWVWNLEKMDLSGNEIEYMEPHVF 276
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 100/236 (42%), Gaps = 27/236 (11%)
Query: 3 CVLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
C ++ F KL V +L+ N + +LP + +P+++++DL NK+ L + F ++
Sbjct: 102 CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPDLFHGLR 161
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
+L L + N I + + LK + +G N+L +L
Sbjct: 162 KLTTLHMRANAIQFVPVRIFQDCRSLKFLDIGYNQLKSL--------------------- 200
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
N K +L H HN+L + + + SL SL N + + +L NL
Sbjct: 201 -ARNSFAGLFKLTEL-HLEHNDLVKVNFAHFPRLISLHSLCLRRNKVAIVVSSLDWVWNL 258
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ LS N+IE++ F L L + N L Y+ L S KSL + L N
Sbjct: 259 EKMDLSGNEIEYMEPHVFETVPHLQSLQLDSNRLTYIEPRILNSWKSLTSITLAGN 314
Score = 37.5 bits (83), Expect = 0.12
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGLPSLCSADLSFNKIHTVNYD 387
+ +NHI +++ + L ++EL N IT L + F +P+L S DLS+NK+ + D
Sbjct: 96 LDHNHICSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMPNLRSVDLSYNKLQALAPD 155
Query: 388 L 388
L
Sbjct: 156 L 156
>M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein.
Length = 394
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/226 (25%), Positives = 108/226 (47%), Gaps = 6/226 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + EL + + L H+ L L NKI+K+ E+ F ++ ++ L ++ N + EI +
Sbjct: 123 LQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRNVQKLYISKNHLVEIPPN 182
Query: 81 ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPT-KAKKMQLIHA 138
LP L + + N++ + G L ++ I + N L++ E K+ +
Sbjct: 183 -LPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRI 241
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDF 197
+ +L +P DL +L L+ N I++++ E L + L R+GL N+I +
Sbjct: 242 SEAKLTGIPKDLP--ETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSL 299
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+ L EL + N+L + L LK L+ + L N +T+ + +
Sbjct: 300 SFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVND 345
Score = 70.1 bits (164), Expect = 2e-11
Identities = 58/226 (25%), Positives = 106/226 (46%), Gaps = 4/226 (1%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH-LGINKL 96
P LDL N I++L ++DF+ +Q L L++ +N+IS+I + A L++V L I+K
Sbjct: 116 PDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAF-SPLRNVQKLYISKN 174
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ + L + I+ N ++ + + + + M I N L++ + L
Sbjct: 175 HLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL 234
Query: 157 QSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
+ Y + K L + L NKI+ + +D KL L + +N+++ +
Sbjct: 235 KLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMI 294
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
NGSL L +LR L+L +N + + L+ L V+ L N I+
Sbjct: 295 ENGSLSFLPTLRELHLDNNKLARVP-SGLPDLKLLQVVYLHSNNIT 339
Score = 42.3 bits (95), Expect = 0.004
Identities = 48/180 (26%), Positives = 86/180 (47%), Gaps = 14/180 (7%)
Query: 112 IFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE 171
+ +N N + I + + + +Q ++ + N L +P +L SL L + N I+ + +
Sbjct: 146 VLVN-NKISKIHEKAFSPLRNVQKLYISKNHLVEIPPNLP--SSLVELRIHDNRIRKVPK 202
Query: 172 TLQKS-RNLMRIGLSFNKIEFLTKDDFT-EAEKLAELDIAYNELKYLNGSLRSL-KSLRY 228
+ RN+ I + N +E + + KL L I+ E K L G + L ++L
Sbjct: 203 GVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLKLNYLRIS--EAK-LTGIPKDLPETLNE 259
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLELRLDHNHI 287
L+L HN + L+++ +L + L HNQI ++ GSL L + EL LD+N +
Sbjct: 260 LHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLR----ELHLDNNKL 315
>BC034947-1|AAH34947.1| 716|Homo sapiens leucine rich repeat
neuronal 1 protein.
Length = 716
Score = 75.4 bits (177), Expect = 5e-13
Identities = 77/274 (28%), Positives = 127/274 (46%), Gaps = 12/274 (4%)
Query: 22 ADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDA 81
+ N+ + L +L + TL L N+IT++T+ +D+ L+ L + NQIS I A
Sbjct: 103 SQNNFTNIKEVGLANLTQLTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHA 162
Query: 82 LP--KGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
K L +HL NKL ++ D +LE + I N + I + ++ +
Sbjct: 163 FAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVL 222
Query: 139 AHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDD 196
A L +P + L + SL+SL FY N + + + LQK +L + L+ N I + + D
Sbjct: 223 AGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGD 282
Query: 197 FTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN----YMTEFSLQEIKGLRRL 250
F +L EL I EL ++ +L +L L L T+N Y+ + + + L L
Sbjct: 283 FKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESL 342
Query: 251 SVIDLSHNQISLLT-GSLENLVDVETRVLELRLD 283
+ + + N I T SL NL ++ LR D
Sbjct: 343 MLNNNALNAIYQKTVESLPNLREISIHSNPLRCD 376
Score = 52.8 bits (121), Expect = 3e-06
Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD- 71
LD ++ S DN L ++P+ LQ +P +K LDL +N I K+ E DF+++ L+ L + +
Sbjct: 238 LDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNM 297
Query: 72 NQISEIEK---DALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELP 127
++ +++ D LP+ K KL+ ++ A R + LE + +N N L +I +
Sbjct: 298 GELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAIYQKTV 357
Query: 128 TKAKKMQLIHAAHNELQ 144
++ I N L+
Sbjct: 358 ESLPNLREISIHSNPLR 374
Score = 44.4 bits (100), Expect = 0.001
Identities = 60/291 (20%), Positives = 109/291 (37%), Gaps = 16/291 (5%)
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L +PS+L Q L NNI + LQ+ NL + S N + + +
Sbjct: 63 LTRIPSNLS--SDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQ 120
Query: 203 LAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N++ + L+ L +L+ L + HN ++ S GL+ L + L+ N++
Sbjct: 121 LTTLHLEENQITEMTDYCLQDLSNLQELYINHNQISTISAHAFAGLKNLLRLHLNSNKLK 180
Query: 262 LLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXX-XXXXXXXXXXXXXIQKIXXXXXXX 320
++ D + L + N + + I
Sbjct: 181 VID---SRWFDSTPNLEILMIGENPVIGILDMNFKPLANLRSLVLAGMYLTDIPGNALVG 237
Query: 321 XXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFN 379
N + + + + +PSL+ L + N I + + DF + L +L N
Sbjct: 238 LDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEGDFKNMLRL--KELGIN 295
Query: 380 KIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDH--LYELVTVFESL 428
+ +LVS R ++ +P + K+ +NP L H + V ESL
Sbjct: 296 NMG----ELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESL 342
Score = 36.7 bits (81), Expect = 0.22
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 19/170 (11%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
LA L ++P + L L +++L NK+ K+ + + + L+ L + N I +I++
Sbjct: 222 LAGMYLTDIPGNALVGLDSLESLSFYDNKLVKVPQLALQKVPSLKFLDLNKNPIHKIQEG 281
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
L+ LGIN + G L +D + N L +E T K+ IH
Sbjct: 282 DFKNMLRLKELGINNM----GELVSVD--RYALDNLPELTKLE---ATNNPKLSYIHRL- 331
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+ +P+L+SL N + ++ +T++ NL I + N +
Sbjct: 332 --------AFRSVPALESLMLNNNALNAIYQKTVESLPNLREISIHSNPL 373
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 74.9 bits (176), Expect = 7e-13
Identities = 65/269 (24%), Positives = 123/269 (45%), Gaps = 6/269 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K +VF +L + L N + + L ++ LDL N++ L E+ F + L
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGL 292
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
L ++ N I+ + L+ + LG N++ L + L LE + ++ N L+
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQE 352
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNL 179
++ + +++ + N L++LP + + + L SL+ G+ + + T L
Sbjct: 353 VKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGL 412
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTE 238
R+ L N + + + +L ELD+ N+L +L L + L L YL L+ N + E
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 472
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+R +D+SHN++ L SL
Sbjct: 473 LPADALGPLQRAFWLDVSHNRLEALPNSL 501
Score = 71.7 bits (168), Expect = 6e-12
Identities = 68/247 (27%), Positives = 116/247 (46%), Gaps = 11/247 (4%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALR 104
N ++ + F+++ L L + Q+ +E AL + L H+HL N+L +L G
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 105 DLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYG 163
L + ++ N L +E+ L + ++ N L LP + + + SL+ L G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 164 NNIKSLDETLQKS-RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLR 221
N + L L L + LS N + + + F + +L +L + N + + G+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 222 SLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLEL 280
LK+LR+L+L+HN + GL L V+ LSHN I SL + ++L +E EL
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLE----EL 319
Query: 281 RLDHNHI 287
+L HN I
Sbjct: 320 QLGHNRI 326
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/265 (23%), Positives = 126/265 (47%), Gaps = 6/265 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ ++F+ L + L+ N+L + +V LP ++ L L RN I + F ++ L
Sbjct: 209 LQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKAL 268
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L ++ N+++ + +D P GL+ + L N + +L +DL LE + + N ++
Sbjct: 269 RWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 328
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ +++++ HN+LQ + + L + ++ + GN +++L E + + L
Sbjct: 329 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKL 388
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTE 238
+ L + + + FT L L + N L + SL L L L+LT N +T
Sbjct: 389 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH 448
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ +GL +L + LS N+++ L
Sbjct: 449 LPHRLFQGLGKLEYLLLSRNRLAEL 473
Score = 62.1 bits (144), Expect = 5e-09
Identities = 70/253 (27%), Positives = 109/253 (43%), Gaps = 9/253 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E F L + L+ N++ L + L ++ L L N+I +L E F + +L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 65 EHLLVADNQISEIEKDALPKGLKHV---HLGINKLNTL-NGALRDLDDLEWIFINANNLK 120
E L + NQ+ E++ A GL +V +L N L L R L L + + + L
Sbjct: 341 EVLTLDHNQLQEVKAGAF-LGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLG 399
Query: 121 SIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRN 178
I T ++ + N L + L + L L N + L L Q
Sbjct: 400 RIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGK 459
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
L + LS N++ L D ++ LD+++N L+ L N L L LRYL+L +N +
Sbjct: 460 LEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Query: 238 EFSLQEIKGLRRL 250
F+ Q GL RL
Sbjct: 520 TFTPQP-PGLERL 531
Score = 59.7 bits (138), Expect = 3e-08
Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 11/307 (3%)
Query: 80 DALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
D +P G + + L N L+++ A ++L L ++ + L S+E + + + +H
Sbjct: 70 DGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHL 129
Query: 139 AHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDD 196
N+L+SL P+L SL N + L++ L + +L + L +N + L
Sbjct: 130 ERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAA 189
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L EL +A N L YL +L S L LR L+L+ N + L RL + L
Sbjct: 190 FRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYL 249
Query: 256 SHNQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKI 313
N I+ + G+ L + L L HN + I +
Sbjct: 250 DRNLIAAVAPGAFLGLKALRW----LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 305
Query: 314 XXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLC 372
+ +N I L E S L LE L HN + V F GL ++
Sbjct: 306 RPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVA 365
Query: 373 SADLSFN 379
+LS N
Sbjct: 366 VMNLSGN 372
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 74.9 bits (176), Expect = 7e-13
Identities = 97/433 (22%), Positives = 178/433 (41%), Gaps = 24/433 (5%)
Query: 21 LADNSLPELPRHVLQHLPH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L D S L R + + LP V LDL N+++ + +Q L + + +N++ I
Sbjct: 57 LLDCSRKRLAR-LPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 80 -DALPKGLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ + + L N++ L L++ LE + +++NN+ ++ P A +++ ++
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP--ALQLKYLY 173
Query: 138 AAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N + S+ L +L L N I ++ + K L + L+ NKI+ +
Sbjct: 174 LNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGL 233
Query: 196 DFTEAEKLAELDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
F L L + N + K ++G+ L ++ L L HN +TE + + GL L +
Sbjct: 234 TFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELH 293
Query: 255 LSHNQISLLTGSLENLVDVETRVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKI 313
LS N I+ ++ ++ EL L NH+ + I
Sbjct: 294 LSQNAINRISPDAWEFCQ---KLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYI 350
Query: 314 XXXXXXXXXXXXXXXVSYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLP 369
+ N I+ T+E+ + F L L LI N I ++ K F GL
Sbjct: 351 ADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLD 410
Query: 370 SLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLN 429
+L DLS N I ++ + S+ + + +++L + +LCD L L N
Sbjct: 411 ALEHLDLSDNAIMSLQGNAFSQMK-------KLQQLHLNTSSLLCDCQLKWLPQWVAENN 463
Query: 430 ARVSGASTCVAPQ 442
+ ++C PQ
Sbjct: 464 FQSFVNASCAHPQ 476
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/312 (23%), Positives = 141/312 (45%), Gaps = 31/312 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K S + L + L +N L +P ++ ++ L L N+I ++ E ++ Q L
Sbjct: 89 IKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 147
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD--LDDLEWIFINANNLKSI 122
E L ++ N ISE++ LK+++L N++ ++ D + L + +N N + +I
Sbjct: 148 ETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNI-KSLD---------E 171
++ K ++Q + N+++++ + + +L+SL N + K +D E
Sbjct: 208 PPKM-FKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 266
Query: 172 TLQKSRN---------------LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
LQ N L + LS N I ++ D + +KL+ELD+ +N L L
Sbjct: 267 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRL 326
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ S L L L++ +N ++ + +GL L +DL +N+IS +
Sbjct: 327 DDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLD 386
Query: 276 RVLELRLDHNHI 287
++ L L N I
Sbjct: 387 KLRRLILQGNRI 398
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE---DFRDI 61
L +S F L L++ + +N + + + L +KTLDL N+I+ E+ F +
Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGL 385
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANN 118
+L L++ N+I I K A L+H+ L N + +L G A + L+ + +N ++
Sbjct: 386 DKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSS 445
Query: 119 L 119
L
Sbjct: 446 L 446
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 74.9 bits (176), Expect = 7e-13
Identities = 97/433 (22%), Positives = 178/433 (41%), Gaps = 24/433 (5%)
Query: 21 LADNSLPELPRHVLQHLPH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L D S L R + + LP V LDL N+++ + +Q L + + +N++ I
Sbjct: 57 LLDCSRKRLAR-LPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 80 -DALPKGLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ + + L N++ L L++ LE + +++NN+ ++ P A +++ ++
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP--ALQLKYLY 173
Query: 138 AAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N + S+ L +L L N I ++ + K L + L+ NKI+ +
Sbjct: 174 LNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGL 233
Query: 196 DFTEAEKLAELDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
F L L + N + K ++G+ L ++ L L HN +TE + + GL L +
Sbjct: 234 TFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELH 293
Query: 255 LSHNQISLLTGSLENLVDVETRVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKI 313
LS N I+ ++ ++ EL L NH+ + I
Sbjct: 294 LSQNAINRISPDAWEFCQ---KLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYI 350
Query: 314 XXXXXXXXXXXXXXXVSYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLP 369
+ N I+ T+E+ + F L L LI N I ++ K F GL
Sbjct: 351 ADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLD 410
Query: 370 SLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLN 429
+L DLS N I ++ + S+ + + +++L + +LCD L L N
Sbjct: 411 ALEHLDLSDNAIMSLQGNAFSQMK-------KLQQLHLNTSSLLCDCQLKWLPQWVAENN 463
Query: 430 ARVSGASTCVAPQ 442
+ ++C PQ
Sbjct: 464 FQSFVNASCAHPQ 476
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/312 (23%), Positives = 141/312 (45%), Gaps = 31/312 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K S + L + L +N L +P ++ ++ L L N+I ++ E ++ Q L
Sbjct: 89 IKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 147
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD--LDDLEWIFINANNLKSI 122
E L ++ N ISE++ LK+++L N++ ++ D + L + +N N + +I
Sbjct: 148 ETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNI-KSLD---------E 171
++ K ++Q + N+++++ + + +L+SL N + K +D E
Sbjct: 208 PPKM-FKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 266
Query: 172 TLQKSRN---------------LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
LQ N L + LS N I ++ D + +KL+ELD+ +N L L
Sbjct: 267 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRL 326
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ S L L L++ +N ++ + +GL L +DL +N+IS +
Sbjct: 327 DDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLD 386
Query: 276 RVLELRLDHNHI 287
++ L L N I
Sbjct: 387 KLRRLILQGNRI 398
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE---DFRDI 61
L +S F L L++ + +N + + + L +KTLDL N+I+ E+ F +
Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGL 385
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANN 118
+L L++ N+I I K A L+H+ L N + +L G A + L+ + +N ++
Sbjct: 386 DKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSS 445
Query: 119 L 119
L
Sbjct: 446 L 446
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 74.9 bits (176), Expect = 7e-13
Identities = 97/433 (22%), Positives = 178/433 (41%), Gaps = 24/433 (5%)
Query: 21 LADNSLPELPRHVLQHLPH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L D S L R + + LP V LDL N+++ + +Q L + + +N++ I
Sbjct: 57 LLDCSRKRLAR-LPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 80 -DALPKGLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ + + L N++ L L++ LE + +++NN+ ++ P A +++ ++
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP--ALQLKYLY 173
Query: 138 AAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N + S+ L +L L N I ++ + K L + L+ NKI+ +
Sbjct: 174 LNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGL 233
Query: 196 DFTEAEKLAELDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
F L L + N + K ++G+ L ++ L L HN +TE + + GL L +
Sbjct: 234 TFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELH 293
Query: 255 LSHNQISLLTGSLENLVDVETRVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKI 313
LS N I+ ++ ++ EL L NH+ + I
Sbjct: 294 LSQNAINRISPDAWEFCQ---KLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYI 350
Query: 314 XXXXXXXXXXXXXXXVSYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLP 369
+ N I+ T+E+ + F L L LI N I ++ K F GL
Sbjct: 351 ADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLD 410
Query: 370 SLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLN 429
+L DLS N I ++ + S+ + + +++L + +LCD L L N
Sbjct: 411 ALEHLDLSDNAIMSLQGNAFSQMK-------KLQQLHLNTSSLLCDCQLKWLPQWVAENN 463
Query: 430 ARVSGASTCVAPQ 442
+ ++C PQ
Sbjct: 464 FQSFVNASCAHPQ 476
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/312 (23%), Positives = 141/312 (45%), Gaps = 31/312 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K S + L + L +N L +P ++ ++ L L N+I ++ E ++ Q L
Sbjct: 89 IKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 147
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD--LDDLEWIFINANNLKSI 122
E L ++ N ISE++ LK+++L N++ ++ D + L + +N N + +I
Sbjct: 148 ETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNI-KSLD---------E 171
++ K ++Q + N+++++ + + +L+SL N + K +D E
Sbjct: 208 PPKM-FKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 266
Query: 172 TLQKSRN---------------LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
LQ N L + LS N I ++ D + +KL+ELD+ +N L L
Sbjct: 267 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRL 326
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ S L L L++ +N ++ + +GL L +DL +N+IS +
Sbjct: 327 DDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLD 386
Query: 276 RVLELRLDHNHI 287
++ L L N I
Sbjct: 387 KLRRLILQGNRI 398
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE---DFRDI 61
L +S F L L++ + +N + + + L +KTLDL N+I+ E+ F +
Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGL 385
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANN 118
+L L++ N+I I K A L+H+ L N + +L G A + L+ + +N ++
Sbjct: 386 DKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSS 445
Query: 119 L 119
L
Sbjct: 446 L 446
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 74.9 bits (176), Expect = 7e-13
Identities = 89/414 (21%), Positives = 169/414 (40%), Gaps = 22/414 (5%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK-DALPKGLKHVHLGINKL- 96
H+ DL N+++ + +Q L + + +N++ I + + + L N++
Sbjct: 15 HISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIV 74
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMP 154
L L++ LE + +++NN+ ++ P A +++ ++ N + S+ L
Sbjct: 75 EILPEHLKEFQSLETLDLSSNNISELQTAFP--ALQLKYLYLNSNRVTSMEPGYFDNLAN 132
Query: 155 SLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL- 213
+L L N I ++ + K L + L+ NKI+ + F L L + N +
Sbjct: 133 TLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVT 192
Query: 214 KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDV 273
K ++G+ L ++ L L HN +TE + + GL L + LS N I+ ++
Sbjct: 193 KLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQ- 251
Query: 274 ETRVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYN 332
++ EL L NH+ + I + N
Sbjct: 252 --KLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNN 309
Query: 333 HIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDL 388
I+ T+E+ + F L L LI N I ++ K F GL +L DLS N I ++ +
Sbjct: 310 EISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNA 369
Query: 389 VSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
S+ + + +++L + +LCD L L N + ++C PQ
Sbjct: 370 FSQMK-------KLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQ 416
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/312 (23%), Positives = 141/312 (45%), Gaps = 31/312 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K S + L + L +N L +P ++ ++ L L N+I ++ E ++ Q L
Sbjct: 29 IKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 87
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD--LDDLEWIFINANNLKSI 122
E L ++ N ISE++ LK+++L N++ ++ D + L + +N N + +I
Sbjct: 88 ETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 147
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNI-KSLD---------E 171
++ K ++Q + N+++++ + + +L+SL N + K +D E
Sbjct: 148 PPKM-FKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 206
Query: 172 TLQKSRN---------------LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
LQ N L + LS N I ++ D + +KL+ELD+ +N L L
Sbjct: 207 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRL 266
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ S L L L++ +N ++ + +GL L +DL +N+IS +
Sbjct: 267 DDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLD 326
Query: 276 RVLELRLDHNHI 287
++ L L N I
Sbjct: 327 KLRRLILQGNRI 338
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE---DFRDI 61
L +S F L L++ + +N + + + L +KTLDL N+I+ E+ F +
Sbjct: 266 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGL 325
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANN 118
+L L++ N+I I K A L+H+ L N + +L G A + L+ + +N ++
Sbjct: 326 DKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSS 385
Query: 119 L 119
L
Sbjct: 386 L 386
Score = 36.3 bits (80), Expect = 0.29
Identities = 32/124 (25%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L N L L L + TL + N+++ + + FR + L+ L + +N+IS +D
Sbjct: 258 LTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIED 317
Query: 81 ------ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKM 133
L K L+ + L N++ ++ A LD LE + ++ N + S++ ++ KK+
Sbjct: 318 MNGAFSGLDK-LRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKL 376
Query: 134 QLIH 137
Q +H
Sbjct: 377 QQLH 380
Score = 35.9 bits (79), Expect = 0.38
Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 11/92 (11%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGIN 94
L ++ L L N+I +T++ F + LEHL ++DN I ++ +A K L+ +HL +
Sbjct: 325 LDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTS 384
Query: 95 KLNTLNGALRDLDDLEWI--FINANNLKSIEN 124
L L D L+W+ ++ NN +S N
Sbjct: 385 SL------LCDC-QLKWLPQWVAENNFQSFVN 409
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 74.9 bits (176), Expect = 7e-13
Identities = 97/433 (22%), Positives = 178/433 (41%), Gaps = 24/433 (5%)
Query: 21 LADNSLPELPRHVLQHLPH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L D S L R + + LP V LDL N+++ + +Q L + + +N++ I
Sbjct: 57 LLDCSRKRLAR-LPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN 115
Query: 80 -DALPKGLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ + + L N++ L L++ LE + +++NN+ ++ P A +++ ++
Sbjct: 116 LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFP--ALQLKYLY 173
Query: 138 AAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N + S+ L +L L N I ++ + K L + L+ NKI+ +
Sbjct: 174 LNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGL 233
Query: 196 DFTEAEKLAELDIAYNEL-KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVID 254
F L L + N + K ++G+ L ++ L L HN +TE + + GL L +
Sbjct: 234 TFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELH 293
Query: 255 LSHNQISLLTGSLENLVDVETRVLELRLDHNHIF-XXXXXXXXXXXXXXXXXXXXXIQKI 313
LS N I+ ++ ++ EL L NH+ + I
Sbjct: 294 LSQNAINRISPDAWEFCQ---KLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYI 350
Query: 314 XXXXXXXXXXXXXXXVSYNHIT-TLEETSKTF--LPSLEELIAHHNNI-TVLDKDFHGLP 369
+ N I+ T+E+ + F L L LI N I ++ K F GL
Sbjct: 351 ADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLD 410
Query: 370 SLCSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLN 429
+L DLS N I ++ + S+ + + +++L + +LCD L L N
Sbjct: 411 ALEHLDLSDNAIMSLQGNAFSQMK-------KLQQLHLNTSSLLCDCQLKWLPQWVAENN 463
Query: 430 ARVSGASTCVAPQ 442
+ ++C PQ
Sbjct: 464 FQSFVNASCAHPQ 476
Score = 66.1 bits (154), Expect = 3e-10
Identities = 73/312 (23%), Positives = 141/312 (45%), Gaps = 31/312 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K S + L + L +N L +P ++ ++ L L N+I ++ E ++ Q L
Sbjct: 89 IKASSMSHLQSLREVKLNNNELETIP-NLGPVSANITLLSLAGNRIVEILPEHLKEFQSL 147
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD--LDDLEWIFINANNLKSI 122
E L ++ N ISE++ LK+++L N++ ++ D + L + +N N + +I
Sbjct: 148 ETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNI-KSLD---------E 171
++ K ++Q + N+++++ + + +L+SL N + K +D E
Sbjct: 208 PPKM-FKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNME 266
Query: 172 TLQKSRN---------------LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
LQ N L + LS N I ++ D + +KL+ELD+ +N L L
Sbjct: 267 ILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRL 326
Query: 217 -NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ S L L L++ +N ++ + +GL L +DL +N+IS +
Sbjct: 327 DDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLD 386
Query: 276 RVLELRLDHNHI 287
++ L L N I
Sbjct: 387 KLRRLILQGNRI 398
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/121 (27%), Positives = 60/121 (49%), Gaps = 6/121 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE---DFRDI 61
L +S F L L++ + +N + + + L +KTLDL N+I+ E+ F +
Sbjct: 326 LDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGL 385
Query: 62 QELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANN 118
+L L++ N+I I K A L+H+ L N + +L G A + L+ + +N ++
Sbjct: 386 DKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSS 445
Query: 119 L 119
L
Sbjct: 446 L 446
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 74.9 bits (176), Expect = 7e-13
Identities = 65/269 (24%), Positives = 123/269 (45%), Gaps = 6/269 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K +VF +L + L N + + L ++ LDL N++ L E+ F + L
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGL 292
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
L ++ N I+ + L+ + LG N++ L + L LE + ++ N L+
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQE 352
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNL 179
++ + +++ + N L++LP + + + L SL+ G+ + + T L
Sbjct: 353 VKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGL 412
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTE 238
R+ L N + + + +L ELD+ N+L +L L + L L YL L+ N + E
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 472
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+R +D+SHN++ L SL
Sbjct: 473 LPADALGPLQRAFWLDVSHNRLEALPNSL 501
Score = 71.7 bits (168), Expect = 6e-12
Identities = 68/247 (27%), Positives = 116/247 (46%), Gaps = 11/247 (4%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALR 104
N ++ + F+++ L L + Q+ +E AL + L H+HL N+L +L G
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 105 DLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYG 163
L + ++ N L +E+ L + ++ N L LP + + + SL+ L G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 164 NNIKSLDETLQKS-RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLR 221
N + L L L + LS N + + + F + +L +L + N + + G+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 222 SLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLEL 280
LK+LR+L+L+HN + GL L V+ LSHN I SL + ++L +E EL
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLE----EL 319
Query: 281 RLDHNHI 287
+L HN I
Sbjct: 320 QLGHNRI 326
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/265 (23%), Positives = 126/265 (47%), Gaps = 6/265 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ ++F+ L + L+ N+L + +V LP ++ L L RN I + F ++ L
Sbjct: 209 LQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKAL 268
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L ++ N+++ + +D P GL+ + L N + +L +DL LE + + N ++
Sbjct: 269 RWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 328
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ +++++ HN+LQ + + L + ++ + GN +++L E + + L
Sbjct: 329 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKL 388
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTE 238
+ L + + + FT L L + N L + SL L L L+LT N +T
Sbjct: 389 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH 448
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ +GL +L + LS N+++ L
Sbjct: 449 LPHRLFQGLGKLEYLLLSRNRLAEL 473
Score = 62.1 bits (144), Expect = 5e-09
Identities = 70/253 (27%), Positives = 109/253 (43%), Gaps = 9/253 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E F L + L+ N++ L + L ++ L L N+I +L E F + +L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 65 EHLLVADNQISEIEKDALPKGLKHV---HLGINKLNTL-NGALRDLDDLEWIFINANNLK 120
E L + NQ+ E++ A GL +V +L N L L R L L + + + L
Sbjct: 341 EVLTLDHNQLQEVKAGAF-LGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLG 399
Query: 121 SIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRN 178
I T ++ + N L + L + L L N + L L Q
Sbjct: 400 RIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGK 459
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
L + LS N++ L D ++ LD+++N L+ L N L L LRYL+L +N +
Sbjct: 460 LEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Query: 238 EFSLQEIKGLRRL 250
F+ Q GL RL
Sbjct: 520 TFTPQP-PGLERL 531
Score = 59.7 bits (138), Expect = 3e-08
Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 11/307 (3%)
Query: 80 DALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
D +P G + + L N L+++ A ++L L ++ + L S+E + + + +H
Sbjct: 70 DGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHL 129
Query: 139 AHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDD 196
N+L+SL P+L SL N + L++ L + +L + L +N + L
Sbjct: 130 ERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAA 189
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L EL +A N L YL +L S L LR L+L+ N + L RL + L
Sbjct: 190 FRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYL 249
Query: 256 SHNQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKI 313
N I+ + G+ L + L L HN + I +
Sbjct: 250 DRNLIAAVAPGAFLGLKALRW----LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 305
Query: 314 XXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLC 372
+ +N I L E S L LE L HN + V F GL ++
Sbjct: 306 RPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVA 365
Query: 373 SADLSFN 379
+LS N
Sbjct: 366 VMNLSGN 372
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 74.9 bits (176), Expect = 7e-13
Identities = 65/269 (24%), Positives = 123/269 (45%), Gaps = 6/269 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+K +VF +L + L N + + L ++ LDL N++ L E+ F + L
Sbjct: 233 IKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGL 292
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS 121
L ++ N I+ + L+ + LG N++ L + L LE + ++ N L+
Sbjct: 293 RVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQE 352
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNL 179
++ + +++ + N L++LP + + + L SL+ G+ + + T L
Sbjct: 353 VKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGL 412
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTE 238
R+ L N + + + +L ELD+ N+L +L L + L L YL L+ N + E
Sbjct: 413 RRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAE 472
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+R +D+SHN++ L SL
Sbjct: 473 LPADALGPLQRAFWLDVSHNRLEALPNSL 501
Score = 71.7 bits (168), Expect = 6e-12
Identities = 68/247 (27%), Positives = 116/247 (46%), Gaps = 11/247 (4%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALR 104
N ++ + F+++ L L + Q+ +E AL + L H+HL N+L +L G
Sbjct: 84 NNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFA 143
Query: 105 DLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYG 163
L + ++ N L +E+ L + ++ N L LP + + + SL+ L G
Sbjct: 144 HTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAG 203
Query: 164 NNIKSLDETLQKS-RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLR 221
N + L L L + LS N + + + F + +L +L + N + + G+
Sbjct: 204 NRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFL 263
Query: 222 SLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLEL 280
LK+LR+L+L+HN + GL L V+ LSHN I SL + ++L +E EL
Sbjct: 264 GLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLE----EL 319
Query: 281 RLDHNHI 287
+L HN I
Sbjct: 320 QLGHNRI 326
Score = 66.1 bits (154), Expect = 3e-10
Identities = 63/265 (23%), Positives = 126/265 (47%), Gaps = 6/265 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ ++F+ L + L+ N+L + +V LP ++ L L RN I + F ++ L
Sbjct: 209 LQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKAL 268
Query: 65 EHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L ++ N+++ + +D P GL+ + L N + +L +DL LE + + N ++
Sbjct: 269 RWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 328
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ +++++ HN+LQ + + L + ++ + GN +++L E + + L
Sbjct: 329 LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKL 388
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTE 238
+ L + + + FT L L + N L + SL L L L+LT N +T
Sbjct: 389 HSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTH 448
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ +GL +L + LS N+++ L
Sbjct: 449 LPHRLFQGLGKLEYLLLSRNRLAEL 473
Score = 62.1 bits (144), Expect = 5e-09
Identities = 70/253 (27%), Positives = 109/253 (43%), Gaps = 9/253 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L E F L + L+ N++ L + L ++ L L N+I +L E F + +L
Sbjct: 281 LLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQL 340
Query: 65 EHLLVADNQISEIEKDALPKGLKHV---HLGINKLNTL-NGALRDLDDLEWIFINANNLK 120
E L + NQ+ E++ A GL +V +L N L L R L L + + + L
Sbjct: 341 EVLTLDHNQLQEVKAGAF-LGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLG 399
Query: 121 SIENELPTKAKKMQLIHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRN 178
I T ++ + N L + L + L L N + L L Q
Sbjct: 400 RIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGK 459
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMT 237
L + LS N++ L D ++ LD+++N L+ L N L L LRYL+L +N +
Sbjct: 460 LEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSLR 519
Query: 238 EFSLQEIKGLRRL 250
F+ Q GL RL
Sbjct: 520 TFTPQP-PGLERL 531
Score = 59.7 bits (138), Expect = 3e-08
Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 11/307 (3%)
Query: 80 DALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
D +P G + + L N L+++ A ++L L ++ + L S+E + + + +H
Sbjct: 70 DGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHL 129
Query: 139 AHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDD 196
N+L+SL P+L SL N + L++ L + +L + L +N + L
Sbjct: 130 ERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAA 189
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRS-LKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
F L EL +A N L YL +L S L LR L+L+ N + L RL + L
Sbjct: 190 FRGLGSLRELVLAGNRLAYLQPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYL 249
Query: 256 SHNQISLLT-GSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKI 313
N I+ + G+ L + L L HN + I +
Sbjct: 250 DRNLIAAVAPGAFLGLKALRW----LDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASL 305
Query: 314 XXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLC 372
+ +N I L E S L LE L HN + V F GL ++
Sbjct: 306 RPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVA 365
Query: 373 SADLSFN 379
+LS N
Sbjct: 366 VMNLSGN 372
>X72913-1|CAA51418.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 73.3 bits (172), Expect = 2e-12
Identities = 62/255 (24%), Positives = 129/255 (50%), Gaps = 16/255 (6%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKIT--KLTEEDFRDIQELEHLLVADNQIS 75
Y +N + + V + + + L N+IT K+ + F ++ LE L + N ++
Sbjct: 109 YVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLT 168
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQ 134
+ LP+ L+ +HL N+++ + N AL L++L +++ N ++ + + + + +
Sbjct: 169 RMP-GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGLRSLY 226
Query: 135 LIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI--EF 191
L+ ++N L+ +P L +L+ LY NN+ ++ D + + L+ + LS N +
Sbjct: 227 LLDLSYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNG 284
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L + F + L ELD++YN+L+ + +L++L YL N + EFS+ + +
Sbjct: 285 LASNTFNSSS-LLELDLSYNQLQKIPPVNTNLENL-YLQ--GNRINEFSISSFCTV--VD 338
Query: 252 VIDLSHNQISLLTGS 266
V++ S Q+ L G+
Sbjct: 339 VVNFSQLQVVRLDGN 353
Score = 62.5 bits (145), Expect = 4e-09
Identities = 53/210 (25%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 82 LPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHA 138
+P +K+V+ N++ ++ G + L WI ++ N + S + ++ +K + ++ ++
Sbjct: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HN L +P L SL+ L+ N I + + L+ NL + L N+I+ +
Sbjct: 163 DHNNLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSS-M 219
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN L+ + L S +L L + HN + +G +L + LSH
Sbjct: 220 RGLRSLYLLDLSYNHLRKVPDGLPS--ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHI 287
N SL L + + +LEL L +N +
Sbjct: 278 N--SLTNNGLASNTFNSSSLLELDLSYNQL 305
Score = 54.0 bits (124), Expect = 1e-06
Identities = 47/193 (24%), Positives = 98/193 (50%), Gaps = 13/193 (6%)
Query: 5 LKESVFTKLDLVDYFSLADNSLP--ELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
++E VF + + +L N + ++ R V L H++ L L N +T++ R ++
Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLR 179
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
EL HL NQIS + +AL + L ++L N++ + ++R L L + ++ N+L+
Sbjct: 180 EL-HL--DHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLYLLDLSYNHLR 236
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNI--KSLDETLQKSR 177
+ + LP+ ++ ++ HN + ++P S + P L + N++ L S
Sbjct: 237 KVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSS 293
Query: 178 NLMRIGLSFNKIE 190
+L+ + LS+N+++
Sbjct: 294 SLLELDLSYNQLQ 306
Score = 40.3 bits (90), Expect = 0.018
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 14/138 (10%)
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIFXX-XXXXXXXXXXXXXXX 305
LR L + L HN ++ + G L + EL LDHN I
Sbjct: 154 LRHLERLYLDHNNLTRMPGPLPR------SLRELHLDHNQISRVPNNALEGLENLTALYL 207
Query: 306 XXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS-LEELIAHHNNI-TVLDK 363
IQ++ +SYNH+ + + LPS LE+L HNN+ TV D
Sbjct: 208 QHNEIQEVGSSMRGLRSLYLLD-LSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDS 262
Query: 364 DFHGLPSLCSADLSFNKI 381
F G P L LS N +
Sbjct: 263 YFRGAPKLLYVRLSHNSL 280
Score = 31.9 bits (69), Expect = 6.2
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + + L +L L HN I + GL SL DLS+N + V
Sbjct: 183 LDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLYLLDLSYNHLRKV 238
>BC063114-1|AAH63114.1| 384|Homo sapiens ASPN protein protein.
Length = 384
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ + + L + L L NK+TK+ + F ++L L ++ NQ+SEI +
Sbjct: 113 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 172
Query: 81 ALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA- 138
LPK L + + NK+ + + ++ L + ++AN L + E P + + + H
Sbjct: 173 -LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE-PGAFEGVTVFHIR 230
Query: 139 -AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A +L S+P L P+L L+ N I +++ E ++ + L R+GL NKI +
Sbjct: 231 IAEAKLTSVPKGLP--PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 288
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
++ E+ + N+LK + L LK L+ + L N + + +
Sbjct: 289 LANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 335
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 6/224 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNT 98
+ LDL NKI ++ E DF+ + L L++ +N++++I A K L+ ++L N+L+
Sbjct: 109 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 168
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
+ L L + I+ N +K I+ + + ++ + N L + + +
Sbjct: 169 I--PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 226
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ K L+ + L +NKI + +DF ++L L + N++ + N
Sbjct: 227 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 286
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
GSL ++ +R ++L +N + + + L+ L +I L N I+
Sbjct: 287 GSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSIA 329
>AY358329-1|AAQ88695.1| 379|Homo sapiens ASPN protein.
Length = 379
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ + + L + L L NK+TK+ + F ++L L ++ NQ+SEI +
Sbjct: 108 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 167
Query: 81 ALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA- 138
LPK L + + NK+ + + ++ L + ++AN L + E P + + + H
Sbjct: 168 -LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE-PGAFEGVTVFHIR 225
Query: 139 -AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A +L S+P L P+L L+ N I +++ E ++ + L R+GL NKI +
Sbjct: 226 IAEAKLTSVPKGLP--PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 283
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
++ E+ + N+LK + L LK L+ + L N + + +
Sbjct: 284 LANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 330
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 6/224 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNT 98
+ LDL NKI ++ E DF+ + L L++ +N++++I A K L+ ++L N+L+
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
+ L L + I+ N +K I+ + + ++ + N L + + +
Sbjct: 164 I--PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 221
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ K L+ + L +NKI + +DF ++L L + N++ + N
Sbjct: 222 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 281
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
GSL ++ +R ++L +N + + + L+ L +I L N I+
Sbjct: 282 GSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSIA 324
>AY029191-1|AAK31800.1| 381|Homo sapiens periodontal ligament
associated protein 1 protein.
Length = 381
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ + + L + L L NK+TK+ + F ++L L ++ NQ+SEI +
Sbjct: 110 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 169
Query: 81 ALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA- 138
LPK L + + NK+ + + ++ L + ++AN L + E P + + + H
Sbjct: 170 -LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE-PGAFEGVTVFHIR 227
Query: 139 -AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A +L S+P L P+L L+ N I +++ E ++ + L R+GL NKI +
Sbjct: 228 IAEAKLTSVPKGLP--PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 285
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
++ E+ + N+LK + L LK L+ + L N + + +
Sbjct: 286 LANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 332
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 6/224 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNT 98
+ LDL NKI ++ E DF+ + L L++ +N++++I A K L+ ++L N+L+
Sbjct: 106 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 165
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
+ L L + I+ N +K I+ + + ++ + N L + + +
Sbjct: 166 I--PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 223
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ K L+ + L +NKI + +DF ++L L + N++ + N
Sbjct: 224 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 283
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
GSL ++ +R ++L +N + + + L+ L +I L N I+
Sbjct: 284 GSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSIA 326
>AL137848-5|CAI16697.1| 380|Homo sapiens asporin (LRR class 1)
protein.
Length = 380
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ + + L + L L NK+TK+ + F ++L L ++ NQ+SEI +
Sbjct: 109 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 168
Query: 81 ALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA- 138
LPK L + + NK+ + + ++ L + ++AN L + E P + + + H
Sbjct: 169 -LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE-PGAFEGVTVFHIR 226
Query: 139 -AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A +L S+P L P+L L+ N I +++ E ++ + L R+GL NKI +
Sbjct: 227 IAEAKLTSVPKGLP--PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 284
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
++ E+ + N+LK + L LK L+ + L N + + +
Sbjct: 285 LANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 331
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 6/224 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNT 98
+ LDL NKI ++ E DF+ + L L++ +N++++I A K L+ ++L N+L+
Sbjct: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
+ L L + I+ N +K I+ + + ++ + N L + + +
Sbjct: 165 I--PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 222
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ K L+ + L +NKI + +DF ++L L + N++ + N
Sbjct: 223 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 282
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
GSL ++ +R ++L +N + + + L+ L +I L N I+
Sbjct: 283 GSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSIA 325
>AF316824-1|AAK35161.1| 379|Homo sapiens asporin precursor protein.
Length = 379
Score = 73.3 bits (172), Expect = 2e-12
Identities = 59/227 (25%), Positives = 111/227 (48%), Gaps = 8/227 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + E+ + + L + L L NK+TK+ + F ++L L ++ NQ+SEI +
Sbjct: 108 LQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLN 167
Query: 81 ALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA- 138
LPK L + + NK+ + + ++ L + ++AN L + E P + + + H
Sbjct: 168 -LPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIE-PGAFEGVTVFHIR 225
Query: 139 -AHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDD 196
A +L S+P L P+L L+ N I +++ E ++ + L R+GL NKI +
Sbjct: 226 IAEAKLTSVPKGLP--PTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGS 283
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
++ E+ + N+LK + L LK L+ + L N + + +
Sbjct: 284 LANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVND 330
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/224 (22%), Positives = 105/224 (46%), Gaps = 6/224 (2%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNT 98
+ LDL NKI ++ E DF+ + L L++ +N++++I A K L+ ++L N+L+
Sbjct: 104 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 163
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
+ L L + I+ N +K I+ + + ++ + N L + + +
Sbjct: 164 I--PLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTV 221
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-N 217
+ K L+ + L +NKI + +DF ++L L + N++ + N
Sbjct: 222 FHIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIEN 281
Query: 218 GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
GSL ++ +R ++L +N + + + L+ L +I L N I+
Sbjct: 282 GSLANIPRVREIHLENNKLKKIP-SGLPELKYLQIIFLHSNSIA 324
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 72.5 bits (170), Expect = 4e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FD-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 72.1 bits (169), Expect = 5e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFDRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 69.7 bits (163), Expect = 3e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFDRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein
protein.
Length = 693
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L L + N + +I
Sbjct: 378 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIP 437
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 438 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 496
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 497 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 554
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 555 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 612
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 613 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 648
Score = 36.7 bits (81), Expect = 0.22
Identities = 33/165 (20%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKI--TKLTEEDFRDIQELEHLLVADNQ 73
++ L +N + E+ H + + L NKI ++ + + + LE + ++ N+
Sbjct: 515 IEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNK 574
Query: 74 ISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDD--LEWIFINANNLKSIENELPT--- 128
+ + LPK L H+ L N++ + G + + LE+++++ N L + +
Sbjct: 575 LYHVPS-YLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDGMDRVSFYG 633
Query: 129 KAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ + HN+L+S+P ++ M +L L N I+ + + +
Sbjct: 634 AYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRCVSDAV 678
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 72.1 bits (169), Expect = 5e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-EPIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 69.7 bits (163), Expect = 3e-11
Identities = 49/209 (23%), Positives = 104/209 (49%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L E +
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPEPIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L L + N + +I
Sbjct: 350 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIP 409
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 410 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 468
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 469 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 526
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 527 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 584
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 585 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 620
Score = 51.2 bits (117), Expect = 9e-06
Identities = 55/234 (23%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIEKD 80
+N+L + L L + TL+L N +++ F+ ++ L +L + N+ I +
Sbjct: 423 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ- 481
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKA----KKMQL 135
LP ++ ++L N++ + + I + N ++ EN + A + ++
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIE--ENRIAPLAWINQENLES 539
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKI--EF 191
I ++N+L +PS L SL L GN I+ + + L + LSFNK+ +
Sbjct: 540 IDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDG 597
Query: 192 LTKDDFTEA-EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEI 244
+ + F A L EL + +N+LK + ++ +K+L +L L +N + +EI
Sbjct: 598 MDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 651
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 72.1 bits (169), Expect = 5e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 72.1 bits (169), Expect = 5e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>BC035281-1|AAH35281.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 72.1 bits (169), Expect = 5e-12
Identities = 62/255 (24%), Positives = 129/255 (50%), Gaps = 16/255 (6%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKIT--KLTEEDFRDIQELEHLLVADNQIS 75
Y +N + + V + + + L N+IT K+ + F ++ LE L + N ++
Sbjct: 109 YVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLT 168
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQ 134
+ LP+ L+ +HL N+++ + N AL L++L +++ N ++ + + + + +
Sbjct: 169 RMP-GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGLRSLI 226
Query: 135 LIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI--EF 191
L+ ++N L+ +P L +L+ LY NN+ ++ D + + L+ + LS N +
Sbjct: 227 LLDLSYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNG 284
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L + F + L ELD++YN+L+ + +L++L YL N + EFS+ + +
Sbjct: 285 LASNTFNSSS-LLELDLSYNQLQKIPPVNTNLENL-YLQ--GNRINEFSISSFCTV--VD 338
Query: 252 VIDLSHNQISLLTGS 266
V++ S Q+ L G+
Sbjct: 339 VVNFSKLQVLRLDGN 353
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/210 (25%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 82 LPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHA 138
+P +K+V+ N++ ++ G + L WI ++ N + S + ++ +K + ++ ++
Sbjct: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HN L +P L SL+ L+ N I + + L+ NL + L N+I+ +
Sbjct: 163 DHNNLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSS-M 219
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN L+ + L S +L L + HN + +G +L + LSH
Sbjct: 220 RGLRSLILLDLSYNHLRKVPDGLPS--ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHI 287
N SL L + + +LEL L +N +
Sbjct: 278 N--SLTNNGLASNTFNSSSLLELDLSYNQL 305
Score = 53.6 bits (123), Expect = 2e-06
Identities = 47/193 (24%), Positives = 98/193 (50%), Gaps = 13/193 (6%)
Query: 5 LKESVFTKLDLVDYFSLADNSLP--ELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
++E VF + + +L N + ++ R V L H++ L L N +T++ R ++
Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLR 179
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
EL HL NQIS + +AL + L ++L N++ + ++R L L + ++ N+L+
Sbjct: 180 EL-HL--DHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLR 236
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNI--KSLDETLQKSR 177
+ + LP+ ++ ++ HN + ++P S + P L + N++ L S
Sbjct: 237 KVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSS 293
Query: 178 NLMRIGLSFNKIE 190
+L+ + LS+N+++
Sbjct: 294 SLLELDLSYNQLQ 306
Score = 40.3 bits (90), Expect = 0.018
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 14/138 (10%)
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIFXX-XXXXXXXXXXXXXXX 305
LR L + L HN ++ + G L + EL LDHN I
Sbjct: 154 LRHLERLYLDHNNLTRMPGPLPR------SLRELHLDHNQISRVPNNALEGLENLTALYL 207
Query: 306 XXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS-LEELIAHHNNI-TVLDK 363
IQ++ +SYNH+ + + LPS LE+L HNN+ TV D
Sbjct: 208 QHNEIQEVGSSMRGLRSLILLD-LSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDS 262
Query: 364 DFHGLPSLCSADLSFNKI 381
F G P L LS N +
Sbjct: 263 YFRGAPKLLYVRLSHNSL 280
Score = 32.3 bits (70), Expect = 4.7
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + + L +L L HN I + GL SL DLS+N + V
Sbjct: 183 LDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKV 238
>AL359837-1|CAH73821.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 72.1 bits (169), Expect = 5e-12
Identities = 62/255 (24%), Positives = 129/255 (50%), Gaps = 16/255 (6%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKIT--KLTEEDFRDIQELEHLLVADNQIS 75
Y +N + + V + + + L N+IT K+ + F ++ LE L + N ++
Sbjct: 109 YVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLT 168
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQ 134
+ LP+ L+ +HL N+++ + N AL L++L +++ N ++ + + + + +
Sbjct: 169 RMP-GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGLRSLI 226
Query: 135 LIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI--EF 191
L+ ++N L+ +P L +L+ LY NN+ ++ D + + L+ + LS N +
Sbjct: 227 LLDLSYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNG 284
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
L + F + L ELD++YN+L+ + +L++L YL N + EFS+ + +
Sbjct: 285 LASNTFNSSS-LLELDLSYNQLQKIPPVNTNLENL-YLQ--GNRINEFSISSFCTV--VD 338
Query: 252 VIDLSHNQISLLTGS 266
V++ S Q+ L G+
Sbjct: 339 VVNFSKLQVLRLDGN 353
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/210 (25%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 82 LPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHA 138
+P +K+V+ N++ ++ G + L WI ++ N + S + ++ +K + ++ ++
Sbjct: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HN L +P L SL+ L+ N I + + L+ NL + L N+I+ +
Sbjct: 163 DHNNLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSS-M 219
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN L+ + L S +L L + HN + +G +L + LSH
Sbjct: 220 RGLRSLILLDLSYNHLRKVPDGLPS--ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHI 287
N SL L + + +LEL L +N +
Sbjct: 278 N--SLTNNGLASNTFNSSSLLELDLSYNQL 305
Score = 53.6 bits (123), Expect = 2e-06
Identities = 47/193 (24%), Positives = 98/193 (50%), Gaps = 13/193 (6%)
Query: 5 LKESVFTKLDLVDYFSLADNSLP--ELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
++E VF + + +L N + ++ R V L H++ L L N +T++ R ++
Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLR 179
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
EL HL NQIS + +AL + L ++L N++ + ++R L L + ++ N+L+
Sbjct: 180 EL-HL--DHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLR 236
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNI--KSLDETLQKSR 177
+ + LP+ ++ ++ HN + ++P S + P L + N++ L S
Sbjct: 237 KVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSS 293
Query: 178 NLMRIGLSFNKIE 190
+L+ + LS+N+++
Sbjct: 294 SLLELDLSYNQLQ 306
Score = 40.3 bits (90), Expect = 0.018
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 14/138 (10%)
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIFXX-XXXXXXXXXXXXXXX 305
LR L + L HN ++ + G L + EL LDHN I
Sbjct: 154 LRHLERLYLDHNNLTRMPGPLPR------SLRELHLDHNQISRVPNNALEGLENLTALYL 207
Query: 306 XXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS-LEELIAHHNNI-TVLDK 363
IQ++ +SYNH+ + + LPS LE+L HNN+ TV D
Sbjct: 208 QHNEIQEVGSSMRGLRSLILLD-LSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDS 262
Query: 364 DFHGLPSLCSADLSFNKI 381
F G P L LS N +
Sbjct: 263 YFRGAPKLLYVRLSHNSL 280
Score = 32.3 bits (70), Expect = 4.7
Identities = 17/56 (30%), Positives = 26/56 (46%)
Query: 329 VSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + + L +L L HN I + GL SL DLS+N + V
Sbjct: 183 LDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSMRGLRSLILLDLSYNHLRKV 238
>AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L L + N + +I
Sbjct: 350 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIP 409
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 410 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 468
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 469 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 526
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 527 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 584
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 585 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 620
Score = 51.2 bits (117), Expect = 9e-06
Identities = 55/234 (23%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIEKD 80
+N+L + L L + TL+L N +++ F+ ++ L +L + N+ I +
Sbjct: 423 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ- 481
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKA----KKMQL 135
LP ++ ++L N++ + + I + N ++ EN + A + ++
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIE--ENRIAPLAWINQENLES 539
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKI--EF 191
I ++N+L +PS L SL L GN I+ + + L + LSFNK+ +
Sbjct: 540 IDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDG 597
Query: 192 LTKDDFTEA-EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEI 244
+ + F A L EL + +N+LK + ++ +K+L +L L +N + +EI
Sbjct: 598 MDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 651
>AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix
protein 2, female organ and adipocyte specific protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L L + N + +I
Sbjct: 350 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIP 409
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 410 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 468
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 469 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 526
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 527 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 584
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 585 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 620
Score = 51.2 bits (117), Expect = 9e-06
Identities = 55/234 (23%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIEKD 80
+N+L + L L + TL+L N +++ F+ ++ L +L + N+ I +
Sbjct: 423 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ- 481
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKA----KKMQL 135
LP ++ ++L N++ + + I + N ++ EN + A + ++
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIE--ENRIAPLAWINQENLES 539
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKI--EF 191
I ++N+L +PS L SL L GN I+ + + L + LSFNK+ +
Sbjct: 540 IDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDG 597
Query: 192 LTKDDFTEA-EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEI 244
+ + F A L EL + +N+LK + ++ +K+L +L L +N + +EI
Sbjct: 598 MDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 651
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 72.1 bits (169), Expect = 5e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 72.1 bits (169), Expect = 5e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 72.1 bits (169), Expect = 5e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 72.1 bits (169), Expect = 5e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 72.1 bits (169), Expect = 5e-12
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 SLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 72.1 bits (169), Expect = 5e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 SLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/229 (22%), Positives = 110/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix
protein protein.
Length = 699
Score = 72.1 bits (169), Expect = 5e-12
Identities = 72/276 (26%), Positives = 126/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L L + N + +I
Sbjct: 350 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIP 409
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 410 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 468
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 469 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 526
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 527 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 584
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 585 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 620
Score = 51.2 bits (117), Expect = 9e-06
Identities = 55/234 (23%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIEKD 80
+N+L + L L + TL+L N +++ F+ ++ L +L + N+ I +
Sbjct: 423 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ- 481
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKA----KKMQL 135
LP ++ ++L N++ + + I + N ++ EN + A + ++
Sbjct: 482 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIE--ENRIAPLAWINQENLES 539
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKI--EF 191
I ++N+L +PS L SL L GN I+ + + L + LSFNK+ +
Sbjct: 540 IDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDG 597
Query: 192 LTKDDFTEA-EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEI 244
+ + F A L EL + +N+LK + ++ +K+L +L L +N + +EI
Sbjct: 598 MDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 651
>BC094737-1|AAH94737.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 71.7 bits (168), Expect = 6e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 31.9 bits (69), Expect = 6.2
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFNEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>U88879-1|AAC34134.1| 904|Homo sapiens Toll-like receptor 3
protein.
Length = 904
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>DQ445682-1|ABE01399.1| 904|Homo sapiens Toll-like receptor 3
isoform NT2-N protein.
Length = 904
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 71.3 bits (167), Expect = 8e-12
Identities = 50/209 (23%), Positives = 105/209 (50%), Gaps = 6/209 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEK--DALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
+F + +L+ L + +NQ+ + K + L + L+ + LG N+ + L L L+ ++
Sbjct: 156 NFGRLTKLQILELRENQLKMLPKTMNRLTQ-LERLDLGSNEFTEVPEVLEQLSGLKEFWM 214
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
+AN L I + + K++ + + N ++ + + +LQ L N+++ L ET+
Sbjct: 215 DANRLTFIPGFIGS-LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIG 273
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
+N+ + + N++ +L D + ELD ++NE++ L S+ L +LR HN
Sbjct: 274 LLKNITTLKIDENQLMYLP-DSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHN 332
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
Y+ + EI + ++V+ L N++ L
Sbjct: 333 YLQQLP-PEIGSWKNITVLFLHSNKLETL 360
Score = 70.5 bits (165), Expect = 1e-11
Identities = 58/269 (21%), Positives = 122/269 (45%), Gaps = 6/269 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ +FT ++ L N + ELP+ + + + L L N +T L ++ L
Sbjct: 39 KEIFTFEKTLEELYLDANQIEELPKQLF-NCQSLHKLSLPDNDLTTLPAS-IANLINLRE 96
Query: 67 LLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L V+ N I E ++ K L V +N ++ L L +L +++N L+ +
Sbjct: 97 LDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K+Q++ N+L+ LP + + L+ L N + E L++ L +
Sbjct: 157 FG-RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N++ F+ ++L LD++ N ++ + + + ++L+ L L+ N + + + I
Sbjct: 216 ANRLTFI-PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLP-ETIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVE 274
L+ ++ + + NQ+ L S+ L+ VE
Sbjct: 274 LLKNITTLKIDENQLMYLPDSIGGLISVE 302
Score = 68.9 bits (161), Expect = 4e-11
Identities = 59/238 (24%), Positives = 107/238 (44%), Gaps = 7/238 (2%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNT 98
V TLD + ++ +E F + LE L + NQI E+ K + L + L N L T
Sbjct: 24 VTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTT 83
Query: 99 LNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQS 158
L ++ +L +L + ++ N ++ + K + ++ A+ N + LP + +L
Sbjct: 84 LPASIANLINLRELDVSKNGIQEFPENI-KNCKVLTIVEASVNPISKLPDGFSQLLNLTQ 142
Query: 159 LYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNG 218
LY ++ L + L + L N+++ L K +L LD+ NE +
Sbjct: 143 LYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPK-TMNRLTQLERLDLGSNEFTEVPE 201
Query: 219 SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSLENLVDV 273
L L L+ + N +T F I L++L+ +D+S N I ++ + ENL D+
Sbjct: 202 VLEQLSGLKEFWMDANRLT-FIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDL 258
Score = 62.5 bits (145), Expect = 4e-09
Identities = 53/229 (23%), Positives = 111/229 (48%), Gaps = 5/229 (2%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V +L + F + N L +P + L + LD+ +N I ++ EE + L+ LL
Sbjct: 202 VLEQLSGLKEFWMDANRLTFIPGFI-GSLKQLTYLDVSKNNI-EMVEEGISTCENLQDLL 259
Query: 69 VADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ N + ++ E L K + + + N+L L ++ L +E + + N ++++ + +
Sbjct: 260 LSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIG 319
Query: 128 TKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ ++ A HN LQ LP ++ ++ L+ + N +++L E + + L I LS N
Sbjct: 320 -QLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDN 378
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
+++ L FT+ ++L + ++ N+ K L + S + NYM
Sbjct: 379 RLKNL-PFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYM 426
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 71.3 bits (167), Expect = 8e-12
Identities = 68/292 (23%), Positives = 145/292 (49%), Gaps = 29/292 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V KL VD ++ N + L L+ +PH+K +DL N I KL ++ +Q + L
Sbjct: 266 VLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLD 325
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLNTL-------------NGALRDLD------DL 109
+ DN++ +++ + ++ +H N+L TL + L LD L
Sbjct: 326 LRDNKLGDLDA-MIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYL 384
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+++ E +++K++++ HN++ LP+ L SL+ L N + L
Sbjct: 385 SYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARL 443
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKS---L 226
E L+++ ++ + + N++ L + +A+ L L+ + N+L+ L + S ++ L
Sbjct: 444 PERLERT-SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSIL 502
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENLVDVE 274
+ L LT+N +T+ + + G L ++ +++N++ S LE L +++
Sbjct: 503 QELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEID 554
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/261 (23%), Positives = 126/261 (48%), Gaps = 15/261 (5%)
Query: 13 LDLVDYFSLA----DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
LD+ YF A N L +L + + + ++ +D+ RN++ + E + ++LE L
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPN--YLSYMDVSRNRLENVPEW-VCESRKLEVLD 411
Query: 69 VADNQISEIEKDAL-PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
+ NQI E+ L+ + G N+L L L + +E + + N L + L
Sbjct: 412 IGHNQICELPARLFCNSSLRKLLAGHNQLARLPERL-ERTSVEVLDVQHNQLLELPPNLL 470
Query: 128 TKAKKMQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSR-NLMRIG 183
KA ++ ++A+ N+L+SLP + LQ LY N++ L +L +
Sbjct: 471 MKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILH 530
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+++N+++ + E+L E+D++ N+LK + ++ + + + + + H+ E E
Sbjct: 531 MAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTV-IAHSNCIEV-FPE 588
Query: 244 IKGLRRLSVIDLSHNQISLLT 264
+ L + +DLS N++S +T
Sbjct: 589 VMQLPEIKCVDLSCNELSEVT 609
Score = 55.6 bits (128), Expect = 4e-07
Identities = 66/252 (26%), Positives = 114/252 (45%), Gaps = 15/252 (5%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
F L N L LP L+++ + L L N+ T + E + ++ L ++ N + +
Sbjct: 230 FLLDGNFLQSLPAE-LENMKQLSYLGLSFNEFTDIPEV-LEKLTAVDKLCMSGNCVETLR 287
Query: 79 KDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQL 135
AL K +KHV L +N + L D L + + + N L ++ + +++
Sbjct: 288 LQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMI---FNNIEV 344
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+H N+L +L D+ L++LY N + LD L + +S N++E + +
Sbjct: 345 LHCERNQLVTL--DI-CGYFLKALYASSNELVQLD-VYPVPNYLSYMDVSRNRLENVP-E 399
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
E+ KL LDI +N++ L L SLR L HN + L E + V+D+
Sbjct: 400 WVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLAR--LPERLERTSVEVLDV 457
Query: 256 SHNQISLLTGSL 267
HNQ+ L +L
Sbjct: 458 QHNQLLELPPNL 469
Score = 55.2 bits (127), Expect = 6e-07
Identities = 50/214 (23%), Positives = 101/214 (47%), Gaps = 19/214 (8%)
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
Q+L HL + N + + +GL + KL +LN + L D +
Sbjct: 148 QDLTHLNLKQNFLRQNPSLPAARGLNELQR-FTKLKSLNLSNNHLGDFPLAVCS------ 200
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+PT A+ ++ + N L+S+P+ + +M +LQ+ GN ++SL L+ + L
Sbjct: 201 ----IPTLAE----LNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSY 252
Query: 182 IGLSFNKIEFLTK--DDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+GLSFN+ + + + T +KL L+ +LR + +++++L N + +
Sbjct: 253 LGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRL--QALRKMPHIKHVDLRLNVIRKL 310
Query: 240 SLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDV 273
E+ L+ ++ +DL N++ L + N ++V
Sbjct: 311 IADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEV 344
Score = 35.5 bits (78), Expect = 0.50
Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +NSL + +L PH+K L + N++ ++ELE + ++ N++ I
Sbjct: 507 LTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTT 566
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQL 135
+ H + + + + L +++ + ++ N L ++ LP K +++ L
Sbjct: 567 IMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDL 623
Score = 33.9 bits (74), Expect = 1.5
Identities = 47/191 (24%), Positives = 81/191 (42%), Gaps = 27/191 (14%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE--LEHLLVADNQ 73
V+ + N L ELP ++L ++ L+ NK+ L + L+ L + +N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 74 ISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI-------- 122
+++ L LK +H+ N+L + + + L++LE I ++ N LK+I
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCR 571
Query: 123 --------ENELPTKAKKMQL-----IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
N + + MQL + + NEL + L P LQ L GN L
Sbjct: 572 RMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL 631
Query: 170 D-ETLQKSRNL 179
D +TL+ N+
Sbjct: 632 DHKTLELLNNI 642
>BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 71.3 bits (167), Expect = 8e-12
Identities = 63/240 (26%), Positives = 115/240 (47%), Gaps = 13/240 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK + F L+ + + L N + + + + +K L L N+I+ FR + L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 65 EHLLVADNQISEIEKDALPKGLK---HVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
+L ++ NQ+ + + +GL+ +HL N L T+ + +D +LE + + N ++
Sbjct: 136 RNLDLSYNQLHSLGSEQF-RGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMP---SLQSLYFYGNNIKSLDETLQKS- 176
S+ + +++ +H HN+ L +L L P SLQ+LY N I + +T+ +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKL--NLALFPRLVSLQNLYLQWNKISVIGQTMSWTW 252
Query: 177 RNLMRIGLSFNKIE-FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
+L R+ LS N+IE F F L L++ N+L ++ L S SL ++L N
Sbjct: 253 SSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN 312
Score = 58.4 bits (135), Expect = 6e-08
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L H H+ N NG R L+ + +++N + N ++ + ++N+L S
Sbjct: 92 LDHNHISNIDENAFNGIRR----LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 146 LPSD-LKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKL 203
L S+ + + L SL+ N+++++ + Q RNL + L +N+I L ++ F +L
Sbjct: 148 LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRL 207
Query: 204 AELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
EL + +N+ LN +L L SL+ L L N ++ L +DLS N+I
Sbjct: 208 KELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEA 267
Query: 263 LTGSLENLVDVETRVLELRLDHNHI 287
+G ++ + L LD N +
Sbjct: 268 FSG--PSVFQCVPNLQRLNLDSNKL 290
Score = 55.6 bits (128), Expect = 4e-07
Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 20/358 (5%)
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK-KMQLIHAAHNELQSLPSD 149
+G N + L+G+ L + + L S E P + + ++++ +LQ +PS
Sbjct: 1 MGFNVIRLLSGSAVALVIAPTVLLTM--LSSAERGCPKGCRCEGKMVYCESQKLQEIPSS 58
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ SL + N+++ L K N L + L N I + ++ F +L EL +
Sbjct: 59 ISAGCLGLSLRY--NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116
Query: 209 AYNELKY-LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N + Y LN + R + +LR L+L++N + ++ +GLR+L + L N SL T +
Sbjct: 117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN--SLRTIPV 174
Query: 268 ENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXX 326
D L L L +N I K+
Sbjct: 175 RIFQDCRNLEL-LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQN 233
Query: 327 XXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD--KDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + +T SL+ L N I F +P+L +L NK+ +
Sbjct: 234 LYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Query: 385 NYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
+++ S ++N I L N C ++ LV +S C +P+
Sbjct: 294 GQEILD-SWISLN------DISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
>BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 71.3 bits (167), Expect = 8e-12
Identities = 63/240 (26%), Positives = 115/240 (47%), Gaps = 13/240 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK + F L+ + + L N + + + + +K L L N+I+ FR + L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 65 EHLLVADNQISEIEKDALPKGLK---HVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
+L ++ NQ+ + + +GL+ +HL N L T+ + +D +LE + + N ++
Sbjct: 136 RNLDLSYNQLHSLGSEQF-RGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMP---SLQSLYFYGNNIKSLDETLQKS- 176
S+ + +++ +H HN+ L +L L P SLQ+LY N I + +T+ +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKL--NLALFPRLVSLQNLYLQWNKISVIGQTMSWTW 252
Query: 177 RNLMRIGLSFNKIE-FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
+L R+ LS N+IE F F L L++ N+L ++ L S SL ++L N
Sbjct: 253 SSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN 312
Score = 58.4 bits (135), Expect = 6e-08
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L H H+ N NG R L+ + +++N + N ++ + ++N+L S
Sbjct: 92 LDHNHISNIDENAFNGIRR----LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 146 LPSD-LKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKL 203
L S+ + + L SL+ N+++++ + Q RNL + L +N+I L ++ F +L
Sbjct: 148 LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRL 207
Query: 204 AELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
EL + +N+ LN +L L SL+ L L N ++ L +DLS N+I
Sbjct: 208 KELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEA 267
Query: 263 LTGSLENLVDVETRVLELRLDHNHI 287
+G ++ + L LD N +
Sbjct: 268 FSG--PSVFQCVPNLQRLNLDSNKL 290
Score = 55.6 bits (128), Expect = 4e-07
Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 20/358 (5%)
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK-KMQLIHAAHNELQSLPSD 149
+G N + L+G+ L + + L S E P + + ++++ +LQ +PS
Sbjct: 1 MGFNVIRLLSGSAVALVIAPTVLLTM--LSSAERGCPKGCRCEGKMVYCESQKLQEIPSS 58
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ SL + N+++ L K N L + L N I + ++ F +L EL +
Sbjct: 59 ISAGCLGLSLRY--NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116
Query: 209 AYNELKY-LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N + Y LN + R + +LR L+L++N + ++ +GLR+L + L N SL T +
Sbjct: 117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN--SLRTIPV 174
Query: 268 ENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXX 326
D L L L +N I K+
Sbjct: 175 RIFQDCRNLEL-LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQN 233
Query: 327 XXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD--KDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + +T SL+ L N I F +P+L +L NK+ +
Sbjct: 234 LYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Query: 385 NYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
+++ S ++N I L N C ++ LV +S C +P+
Sbjct: 294 GQEILD-SWISLN------DISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
>BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat
transmembrane neuronal 3 protein.
Length = 581
Score = 71.3 bits (167), Expect = 8e-12
Identities = 63/240 (26%), Positives = 115/240 (47%), Gaps = 13/240 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK + F L+ + + L N + + + + +K L L N+I+ FR + L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 65 EHLLVADNQISEIEKDALPKGLK---HVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
+L ++ NQ+ + + +GL+ +HL N L T+ + +D +LE + + N ++
Sbjct: 136 RNLDLSYNQLHSLGSEQF-RGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMP---SLQSLYFYGNNIKSLDETLQKS- 176
S+ + +++ +H HN+ L +L L P SLQ+LY N I + +T+ +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKL--NLALFPRLVSLQNLYLQWNKISVIGQTMSWTW 252
Query: 177 RNLMRIGLSFNKIE-FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
+L R+ LS N+IE F F L L++ N+L ++ L S SL ++L N
Sbjct: 253 SSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN 312
Score = 58.4 bits (135), Expect = 6e-08
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L H H+ N NG R L+ + +++N + N ++ + ++N+L S
Sbjct: 92 LDHNHISNIDENAFNGIRR----LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 146 LPSD-LKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKL 203
L S+ + + L SL+ N+++++ + Q RNL + L +N+I L ++ F +L
Sbjct: 148 LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRL 207
Query: 204 AELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
EL + +N+ LN +L L SL+ L L N ++ L +DLS N+I
Sbjct: 208 KELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEA 267
Query: 263 LTGSLENLVDVETRVLELRLDHNHI 287
+G ++ + L LD N +
Sbjct: 268 FSG--PSVFQCVPNLQRLNLDSNKL 290
Score = 55.6 bits (128), Expect = 4e-07
Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 20/358 (5%)
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK-KMQLIHAAHNELQSLPSD 149
+G N + L+G+ L + + L S E P + + ++++ +LQ +PS
Sbjct: 1 MGFNVIRLLSGSAVALVIAPTVLLTM--LSSAERGCPKGCRCEGKMVYCESQKLQEIPSS 58
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ SL + N+++ L K N L + L N I + ++ F +L EL +
Sbjct: 59 ISAGCLGLSLRY--NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116
Query: 209 AYNELKY-LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N + Y LN + R + +LR L+L++N + ++ +GLR+L + L N SL T +
Sbjct: 117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN--SLRTIPV 174
Query: 268 ENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXX 326
D L L L +N I K+
Sbjct: 175 RIFQDCRNLEL-LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQN 233
Query: 327 XXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD--KDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + +T SL+ L N I F +P+L +L NK+ +
Sbjct: 234 LYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Query: 385 NYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
+++ S ++N I L N C ++ LV +S C +P+
Sbjct: 294 GQEILD-SWISLN------DISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
>BC096335-1|AAH96335.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>BC096334-1|AAH96334.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>BC096333-1|AAH96333.1| 904|Homo sapiens toll-like receptor 3
protein.
Length = 904
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 71.3 bits (167), Expect = 8e-12
Identities = 68/292 (23%), Positives = 145/292 (49%), Gaps = 29/292 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V KL VD ++ N + L L+ +PH+K +DL N I KL ++ +Q + L
Sbjct: 2 VLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLD 61
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLNTL-------------NGALRDLD------DL 109
+ DN++ +++ + ++ +H N+L TL + L LD L
Sbjct: 62 LRDNKLGDLDA-MIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYL 120
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+++ E +++K++++ HN++ LP+ L SL+ L N + L
Sbjct: 121 SYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARL 179
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKS---L 226
E L+++ ++ + + N++ L + +A+ L L+ + N+L+ L + S ++ L
Sbjct: 180 PERLERT-SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSIL 238
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENLVDVE 274
+ L LT+N +T+ + + G L ++ +++N++ S LE L +++
Sbjct: 239 QELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEID 290
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/261 (23%), Positives = 126/261 (48%), Gaps = 15/261 (5%)
Query: 13 LDLVDYFSLA----DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
LD+ YF A N L +L + + + ++ +D+ RN++ + E + ++LE L
Sbjct: 91 LDICGYFLKALYASSNELVQLDVYPVPN--YLSYMDVSRNRLENVPEW-VCESRKLEVLD 147
Query: 69 VADNQISEIEKDAL-PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
+ NQI E+ L+ + G N+L L L + +E + + N L + L
Sbjct: 148 IGHNQICELPARLFCNSSLRKLLAGHNQLARLPERL-ERTSVEVLDVQHNQLLELPPNLL 206
Query: 128 TKAKKMQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSR-NLMRIG 183
KA ++ ++A+ N+L+SLP + LQ LY N++ L +L +
Sbjct: 207 MKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILH 266
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+++N+++ + E+L E+D++ N+LK + ++ + + + + + H+ E E
Sbjct: 267 MAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTV-IAHSNCIEV-FPE 324
Query: 244 IKGLRRLSVIDLSHNQISLLT 264
+ L + +DLS N++S +T
Sbjct: 325 VMQLPEIKCVDLSCNELSEVT 345
Score = 46.4 bits (105), Expect = 3e-04
Identities = 55/215 (25%), Positives = 97/215 (45%), Gaps = 13/215 (6%)
Query: 56 EDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWI 112
E + ++ L ++ N + + AL K +KHV L +N + L D L + +
Sbjct: 1 EVLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQL 60
Query: 113 FINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDET 172
+ N L ++ + ++++H N+L +L D+ L++LY N + LD
Sbjct: 61 DLRDNKLGDLDAMI---FNNIEVLHCERNQLVTL--DI-CGYFLKALYASSNELVQLD-V 113
Query: 173 LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLT 232
L + +S N++E + + E+ KL LDI +N++ L L SLR L
Sbjct: 114 YPVPNYLSYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAG 172
Query: 233 HNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
HN + L E + V+D+ HNQ+ L +L
Sbjct: 173 HNQLAR--LPERLERTSVEVLDVQHNQLLELPPNL 205
Score = 35.5 bits (78), Expect = 0.50
Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +NSL + +L PH+K L + N++ ++ELE + ++ N++ I
Sbjct: 243 LTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTT 302
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQL 135
+ H + + + + L +++ + ++ N L ++ LP K +++ L
Sbjct: 303 IMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDL 359
Score = 33.9 bits (74), Expect = 1.5
Identities = 47/191 (24%), Positives = 81/191 (42%), Gaps = 27/191 (14%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE--LEHLLVADNQ 73
V+ + N L ELP ++L ++ L+ NK+ L + L+ L + +N
Sbjct: 188 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 247
Query: 74 ISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI-------- 122
+++ L LK +H+ N+L + + + L++LE I ++ N LK+I
Sbjct: 248 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCR 307
Query: 123 --------ENELPTKAKKMQL-----IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
N + + MQL + + NEL + L P LQ L GN L
Sbjct: 308 RMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL 367
Query: 170 D-ETLQKSRNL 179
D +TL+ N+
Sbjct: 368 DHKTLELLNNI 378
>BC059372-1|AAH59372.1| 870|Homo sapiens TLR3 protein protein.
Length = 870
Score = 71.3 bits (167), Expect = 8e-12
Identities = 79/279 (28%), Positives = 128/279 (45%), Gaps = 41/279 (14%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRN--KITKLTEEDFRDIQELE-H 66
F L +++ ++ DN +P + ++ L ++K L L + + LT E F + H
Sbjct: 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
Query: 67 LL-VADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE 123
+L + N+IS+IE DA L+ + LG+N++ ++L EW + +E
Sbjct: 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG------QELTGQEW--------RGLE 456
Query: 124 NELPTKAKKMQLIHAAHNE-LQSLPSDLKLMPSLQSLYFYGNNIKSLDET---LQKSRNL 179
N I+ ++N+ LQ + L+PSLQ L +K++D + Q RNL
Sbjct: 457 NIFE--------IYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL----KYLNGS-----LRSLKSLRYLN 230
+ LS N I + D EKL LD+ +N L K+ N L+ L L LN
Sbjct: 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
L N E ++ K L L +IDL N ++ L S+ N
Sbjct: 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
Score = 50.4 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 103/237 (43%), Gaps = 23/237 (9%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + F + L NS+ ++ + ++ TLDL N ++ ++ L
Sbjct: 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ LL+++N+I ++ + L LK + L N++ + G + L +F+N L
Sbjct: 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
P+ +K+ + A+ +++L + + + F G K NL
Sbjct: 234 G------PSLTEKL-CLELANTSIRNLSLSNSQLSTTSNTTFLG----------LKWTNL 276
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNY 235
+ LS+N + + D F +L + YN +++L + SL L ++RYLNL ++
Sbjct: 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
Score = 47.6 bits (108), Expect = 1e-04
Identities = 98/405 (24%), Positives = 151/405 (37%), Gaps = 36/405 (8%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI--- 61
+K + F K + L+ N L L +++ L L NKI L E+ DI
Sbjct: 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEEL-DIFAN 196
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
L+ L ++ NQI E + L +N + L +L + LE + NL
Sbjct: 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ-LGPSLTEKLCLELANTSIRNLSL 255
Query: 122 IENELPT---------KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE 171
++L T K + ++ ++N L + +D +P L+ + NNI+ L
Sbjct: 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF- 314
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAE-KLAELDIAYNELKYLNGSLRSLKSLRYLN 230
S +L GL FN K FT+ LA L K + S + LK L +LN
Sbjct: 315 ----SHSLH--GL-FNVRYLNLKRSFTKQSISLASLP------KIDDFSFQWLKCLEHLN 361
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLE-LRLDHNHI-- 287
+ N + GL L + LS++ SL T + E V + L L L N I
Sbjct: 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
Query: 288 FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS 347
Q++ +SYN L S +PS
Sbjct: 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS 481
Query: 348 LEELIAHH---NNITVLDKDFHGLPSLCSADLSFNKIHTVNYDLV 389
L+ L+ N+ F L +L DLS N I +N D++
Sbjct: 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
Score = 46.4 bits (105), Expect = 3e-04
Identities = 66/281 (23%), Positives = 120/281 (42%), Gaps = 18/281 (6%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ +L N L LP + +LD+ N I+KL E + + L+ L + N++S
Sbjct: 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
Query: 76 EIEKD--ALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
++ A L +HL N + + N +L + ++ N L S + + +
Sbjct: 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
Query: 133 MQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+Q + ++N++Q+L S D+ SL+ L N IK + + GL N +
Sbjct: 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL-FGLFLNNV 231
Query: 190 EF---LTKDDFTEA--EKLAELDIAYNELKYL-NGSLRSLK--SLRYLNLTHNYMTEFSL 241
+ LT+ E + L ++ ++L N + LK +L L+L++N +
Sbjct: 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
Query: 242 QEIKGLRRLSVIDLSHNQIS-LLTGSLENLVDVETRVLELR 281
L +L L +N I L + SL L +V R L L+
Sbjct: 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV--RYLNLK 330
Score = 44.0 bits (99), Expect = 0.001
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 4/109 (3%)
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYM 236
N+ + L+ N++ L +FT +L LD+ +N + L L + L L+ LNL HN +
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
Query: 237 TEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
++ S + L+ + L N I + N + ++ L L HN
Sbjct: 112 SQLSDKTFAFCTNLTELHLMSNSIQKIK---NNPFVKQKNLITLDLSHN 157
Score = 37.1 bits (82), Expect = 0.16
Identities = 37/161 (22%), Positives = 63/161 (39%), Gaps = 7/161 (4%)
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDH 284
++ LNLTHN + +L+ +D+ N IS L L + + + L L H
Sbjct: 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM---LKVLNLQH 108
Query: 285 NHIFXXXXXXXXX-XXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKT 343
N + IQKI +S+N +++ + ++
Sbjct: 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
Query: 344 FLPSLEELIAHHNNITVL---DKDFHGLPSLCSADLSFNKI 381
L +L+EL+ +N I L + D SL +LS N+I
Sbjct: 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Score = 32.3 bits (70), Expect = 4.7
Identities = 18/60 (30%), Positives = 29/60 (48%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N E+P V + L +K +DL N + L F + L+ L + N I+ +EK
Sbjct: 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 71.3 bits (167), Expect = 8e-12
Identities = 68/292 (23%), Positives = 145/292 (49%), Gaps = 29/292 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V KL VD ++ N + L L+ +PH+K +DL N I KL ++ +Q + L
Sbjct: 266 VLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLD 325
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLNTL-------------NGALRDLD------DL 109
+ DN++ +++ + ++ +H N+L TL + L LD L
Sbjct: 326 LRDNKLGDLDA-MIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYL 384
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+++ E +++K++++ HN++ LP+ L SL+ L N + L
Sbjct: 385 SYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARL 443
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKS---L 226
E L+++ ++ + + N++ L + +A+ L L+ + N+L+ L + S ++ L
Sbjct: 444 PERLERT-SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSIL 502
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENLVDVE 274
+ L LT+N +T+ + + G L ++ +++N++ S LE L +++
Sbjct: 503 QELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEID 554
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/261 (23%), Positives = 126/261 (48%), Gaps = 15/261 (5%)
Query: 13 LDLVDYFSLA----DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
LD+ YF A N L +L + + + ++ +D+ RN++ + E + ++LE L
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPN--YLSYMDVSRNRLENVPEW-VCESRKLEVLD 411
Query: 69 VADNQISEIEKDAL-PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
+ NQI E+ L+ + G N+L L L + +E + + N L + L
Sbjct: 412 IGHNQICELPARLFCNSSLRKLLAGHNQLARLPERL-ERTSVEVLDVQHNQLLELPPNLL 470
Query: 128 TKAKKMQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSR-NLMRIG 183
KA ++ ++A+ N+L+SLP + LQ LY N++ L +L +
Sbjct: 471 MKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILH 530
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+++N+++ + E+L E+D++ N+LK + ++ + + + + + H+ E E
Sbjct: 531 MAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTV-IAHSNCIEV-FPE 588
Query: 244 IKGLRRLSVIDLSHNQISLLT 264
+ L + +DLS N++S +T
Sbjct: 589 VMQLPEIKCVDLSCNELSEVT 609
Score = 55.6 bits (128), Expect = 4e-07
Identities = 66/252 (26%), Positives = 114/252 (45%), Gaps = 15/252 (5%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
F L N L LP L+++ + L L N+ T + E + ++ L ++ N + +
Sbjct: 230 FLLDGNFLQSLPAE-LENMKQLSYLGLSFNEFTDIPEV-LEKLTAVDKLCMSGNCVETLR 287
Query: 79 KDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQL 135
AL K +KHV L +N + L D L + + + N L ++ + +++
Sbjct: 288 LQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMI---FNNIEV 344
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+H N+L +L D+ L++LY N + LD L + +S N++E + +
Sbjct: 345 LHCERNQLVTL--DI-CGYFLKALYASSNELVQLD-VYPVPNYLSYMDVSRNRLENVP-E 399
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
E+ KL LDI +N++ L L SLR L HN + L E + V+D+
Sbjct: 400 WVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLAR--LPERLERTSVEVLDV 457
Query: 256 SHNQISLLTGSL 267
HNQ+ L +L
Sbjct: 458 QHNQLLELPPNL 469
Score = 55.2 bits (127), Expect = 6e-07
Identities = 50/214 (23%), Positives = 101/214 (47%), Gaps = 19/214 (8%)
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
Q+L HL + N + + +GL + KL +LN + L D +
Sbjct: 148 QDLTHLNLKQNFLRQNPSLPAARGLNELQR-FTKLKSLNLSNNHLGDFPLAVCS------ 200
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+PT A+ ++ + N L+S+P+ + +M +LQ+ GN ++SL L+ + L
Sbjct: 201 ----IPTLAE----LNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSY 252
Query: 182 IGLSFNKIEFLTK--DDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+GLSFN+ + + + T +KL L+ +LR + +++++L N + +
Sbjct: 253 LGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRL--QALRKMPHIKHVDLRLNVIRKL 310
Query: 240 SLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDV 273
E+ L+ ++ +DL N++ L + N ++V
Sbjct: 311 IADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEV 344
Score = 35.5 bits (78), Expect = 0.50
Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +NSL + +L PH+K L + N++ ++ELE + ++ N++ I
Sbjct: 507 LTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTT 566
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQL 135
+ H + + + + L +++ + ++ N L ++ LP K +++ L
Sbjct: 567 IMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDL 623
Score = 33.9 bits (74), Expect = 1.5
Identities = 47/191 (24%), Positives = 81/191 (42%), Gaps = 27/191 (14%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE--LEHLLVADNQ 73
V+ + N L ELP ++L ++ L+ NK+ L + L+ L + +N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 74 ISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI-------- 122
+++ L LK +H+ N+L + + + L++LE I ++ N LK+I
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCR 571
Query: 123 --------ENELPTKAKKMQL-----IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
N + + MQL + + NEL + L P LQ L GN L
Sbjct: 572 RMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL 631
Query: 170 D-ETLQKSRNL 179
D +TL+ N+
Sbjct: 632 DHKTLELLNNI 642
>AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein.
Length = 513
Score = 71.3 bits (167), Expect = 8e-12
Identities = 63/240 (26%), Positives = 115/240 (47%), Gaps = 13/240 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK + F L+ + + L N + + + + +K L L N+I+ FR + L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 65 EHLLVADNQISEIEKDALPKGLK---HVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
+L ++ NQ+ + + +GL+ +HL N L T+ + +D +LE + + N ++
Sbjct: 136 RNLDLSYNQLHSLGSEQF-RGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMP---SLQSLYFYGNNIKSLDETLQKS- 176
S+ + +++ +H HN+ L +L L P SLQ+LY N I + +T+ +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKL--NLALFPRLVSLQNLYLQWNKISVIGQTMSWTW 252
Query: 177 RNLMRIGLSFNKIE-FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
+L R+ LS N+IE F F L L++ N+L ++ L S SL ++L N
Sbjct: 253 SSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN 312
Score = 58.4 bits (135), Expect = 6e-08
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L H H+ N NG R L+ + +++N + N ++ + ++N+L S
Sbjct: 92 LDHNHISNIDENAFNGIRR----LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 146 LPSD-LKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKL 203
L S+ + + L SL+ N+++++ + Q RNL + L +N+I L ++ F +L
Sbjct: 148 LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRL 207
Query: 204 AELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
EL + +N+ LN +L L SL+ L L N ++ L +DLS N+I
Sbjct: 208 KELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEA 267
Query: 263 LTGSLENLVDVETRVLELRLDHNHI 287
+G ++ + L LD N +
Sbjct: 268 FSG--PSVFQCVPNLQRLNLDSNKL 290
Score = 55.6 bits (128), Expect = 4e-07
Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 20/358 (5%)
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK-KMQLIHAAHNELQSLPSD 149
+G N + L+G+ L + + L S E P + + ++++ +LQ +PS
Sbjct: 1 MGFNVIRLLSGSAVALVIAPTVLLTM--LSSAERGCPKGCRCEGKMVYCESQKLQEIPSS 58
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ SL + N+++ L K N L + L N I + ++ F +L EL +
Sbjct: 59 ISAGCLGLSLRY--NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116
Query: 209 AYNELKY-LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N + Y LN + R + +LR L+L++N + ++ +GLR+L + L N SL T +
Sbjct: 117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN--SLRTIPV 174
Query: 268 ENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXX 326
D L L L +N I K+
Sbjct: 175 RIFQDCRNLEL-LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQN 233
Query: 327 XXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD--KDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + +T SL+ L N I F +P+L +L NK+ +
Sbjct: 234 LYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Query: 385 NYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
+++ S ++N I L N C ++ LV +S C +P+
Sbjct: 294 GQEILD-SWISLN------DISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
>AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat
transmembrane neuronal 3 protein protein.
Length = 513
Score = 71.3 bits (167), Expect = 8e-12
Identities = 63/240 (26%), Positives = 115/240 (47%), Gaps = 13/240 (5%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
LK + F L+ + + L N + + + + +K L L N+I+ FR + L
Sbjct: 76 LKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELILSSNRISYFLNNTFRPVTNL 135
Query: 65 EHLLVADNQISEIEKDALPKGLK---HVHLGINKLNTLNGAL-RDLDDLEWIFINANNLK 120
+L ++ NQ+ + + +GL+ +HL N L T+ + +D +LE + + N ++
Sbjct: 136 RNLDLSYNQLHSLGSEQF-RGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIR 194
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMP---SLQSLYFYGNNIKSLDETLQKS- 176
S+ + +++ +H HN+ L +L L P SLQ+LY N I + +T+ +
Sbjct: 195 SLARNVFAGMIRLKELHLEHNQFSKL--NLALFPRLVSLQNLYLQWNKISVIGQTMSWTW 252
Query: 177 RNLMRIGLSFNKIE-FLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
+L R+ LS N+IE F F L L++ N+L ++ L S SL ++L N
Sbjct: 253 SSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGN 312
Score = 58.4 bits (135), Expect = 6e-08
Identities = 52/205 (25%), Positives = 95/205 (46%), Gaps = 9/205 (4%)
Query: 86 LKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS 145
L H H+ N NG R L+ + +++N + N ++ + ++N+L S
Sbjct: 92 LDHNHISNIDENAFNGIRR----LKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHS 147
Query: 146 LPSD-LKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKL 203
L S+ + + L SL+ N+++++ + Q RNL + L +N+I L ++ F +L
Sbjct: 148 LGSEQFRGLRKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRL 207
Query: 204 AELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
EL + +N+ LN +L L SL+ L L N ++ L +DLS N+I
Sbjct: 208 KELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEA 267
Query: 263 LTGSLENLVDVETRVLELRLDHNHI 287
+G ++ + L LD N +
Sbjct: 268 FSG--PSVFQCVPNLQRLNLDSNKL 290
Score = 55.6 bits (128), Expect = 4e-07
Identities = 78/358 (21%), Positives = 141/358 (39%), Gaps = 20/358 (5%)
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK-KMQLIHAAHNELQSLPSD 149
+G N + L+G+ L + + L S E P + + ++++ +LQ +PS
Sbjct: 1 MGFNVIRLLSGSAVALVIAPTVLLTM--LSSAERGCPKGCRCEGKMVYCESQKLQEIPSS 58
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKIEFLTKDDFTEAEKLAELDI 208
+ SL + N+++ L K N L + L N I + ++ F +L EL +
Sbjct: 59 ISAGCLGLSLRY--NSLQKLKYNQFKGLNQLTWLYLDHNHISNIDENAFNGIRRLKELIL 116
Query: 209 AYNELKY-LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N + Y LN + R + +LR L+L++N + ++ +GLR+L + L N SL T +
Sbjct: 117 SSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLLSLHLRSN--SLRTIPV 174
Query: 268 ENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXX 326
D L L L +N I K+
Sbjct: 175 RIFQDCRNLEL-LDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQN 233
Query: 327 XXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD--KDFHGLPSLCSADLSFNKIHTV 384
+ +N I+ + +T SL+ L N I F +P+L +L NK+ +
Sbjct: 234 LYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKLTFI 293
Query: 385 NYDLVSKSRCTINGVPSILKIYLQDNPVLCDDHLYELVTVFESLNARVSGASTCVAPQ 442
+++ S ++N I L N C ++ LV +S C +P+
Sbjct: 294 GQEILD-SWISLN------DISLAGNIWECSRNICSLVNWLKSFKGLRENTIICASPK 344
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 71.3 bits (167), Expect = 8e-12
Identities = 68/292 (23%), Positives = 145/292 (49%), Gaps = 29/292 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V KL VD ++ N + L L+ +PH+K +DL N I KL ++ +Q + L
Sbjct: 266 VLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLD 325
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLNTL-------------NGALRDLD------DL 109
+ DN++ +++ + ++ +H N+L TL + L LD L
Sbjct: 326 LRDNKLGDLDA-MIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYL 384
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+++ E +++K++++ HN++ LP+ L SL+ L N + L
Sbjct: 385 SYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARL 443
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKS---L 226
E L+++ ++ + + N++ L + +A+ L L+ + N+L+ L + S ++ L
Sbjct: 444 PERLERT-SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSIL 502
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENLVDVE 274
+ L LT+N +T+ + + G L ++ +++N++ S LE L +++
Sbjct: 503 QELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEID 554
Score = 64.1 bits (149), Expect = 1e-09
Identities = 62/261 (23%), Positives = 126/261 (48%), Gaps = 15/261 (5%)
Query: 13 LDLVDYFSLA----DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
LD+ YF A N L +L + + + ++ +D+ RN++ + E + ++LE L
Sbjct: 355 LDICGYFLKALYASSNELVQLDVYPVPN--YLSYMDVSRNRLENVPEW-VCESRKLEVLD 411
Query: 69 VADNQISEIEKDAL-PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
+ NQI E+ L+ + G N+L L L + +E + + N L + L
Sbjct: 412 IGHNQICELPARLFCNSSLRKLLAGHNQLARLPERL-ERTSVEVLDVQHNQLLELPPNLL 470
Query: 128 TKAKKMQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSR-NLMRIG 183
KA ++ ++A+ N+L+SLP + LQ LY N++ L +L +
Sbjct: 471 MKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILH 530
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+++N+++ + E+L E+D++ N+LK + ++ + + + + + H+ E E
Sbjct: 531 MAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTV-IAHSNCIEV-FPE 588
Query: 244 IKGLRRLSVIDLSHNQISLLT 264
+ L + +DLS N++S +T
Sbjct: 589 VMQLPEIKCVDLSCNELSEVT 609
Score = 55.6 bits (128), Expect = 4e-07
Identities = 66/252 (26%), Positives = 114/252 (45%), Gaps = 15/252 (5%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
F L N L LP L+++ + L L N+ T + E + ++ L ++ N + +
Sbjct: 230 FLLDGNFLQSLPAE-LENMKQLSYLGLSFNEFTDIPEV-LEKLTAVDKLCMSGNCVETLR 287
Query: 79 KDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQL 135
AL K +KHV L +N + L D L + + + N L ++ + +++
Sbjct: 288 LQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMI---FNNIEV 344
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+H N+L +L D+ L++LY N + LD L + +S N++E + +
Sbjct: 345 LHCERNQLVTL--DI-CGYFLKALYASSNELVQLD-VYPVPNYLSYMDVSRNRLENVP-E 399
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
E+ KL LDI +N++ L L SLR L HN + L E + V+D+
Sbjct: 400 WVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLAR--LPERLERTSVEVLDV 457
Query: 256 SHNQISLLTGSL 267
HNQ+ L +L
Sbjct: 458 QHNQLLELPPNL 469
Score = 54.4 bits (125), Expect = 1e-06
Identities = 34/140 (24%), Positives = 74/140 (52%), Gaps = 4/140 (2%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTK- 194
++ + N L+S+P+ + +M +LQ+ GN ++SL L+ + L +GLSFN+ + +
Sbjct: 207 LNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEV 266
Query: 195 -DDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVI 253
+ T +KL L+ +LR + +++++L N + + E+ L+ ++ +
Sbjct: 267 LEKLTAVDKLCMSGNCVETLRL--QALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQL 324
Query: 254 DLSHNQISLLTGSLENLVDV 273
DL N++ L + N ++V
Sbjct: 325 DLRDNKLGDLDAMIFNNIEV 344
Score = 35.5 bits (78), Expect = 0.50
Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +NSL + +L PH+K L + N++ ++ELE + ++ N++ I
Sbjct: 507 LTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTT 566
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQL 135
+ H + + + + L +++ + ++ N L ++ LP K +++ L
Sbjct: 567 IMNCRRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDL 623
Score = 33.9 bits (74), Expect = 1.5
Identities = 47/191 (24%), Positives = 81/191 (42%), Gaps = 27/191 (14%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE--LEHLLVADNQ 73
V+ + N L ELP ++L ++ L+ NK+ L + L+ L + +N
Sbjct: 452 VEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNS 511
Query: 74 ISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI-------- 122
+++ L LK +H+ N+L + + + L++LE I ++ N LK+I
Sbjct: 512 LTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCR 571
Query: 123 --------ENELPTKAKKMQL-----IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
N + + MQL + + NEL + L P LQ L GN L
Sbjct: 572 RMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVL 631
Query: 170 D-ETLQKSRNL 179
D +TL+ N+
Sbjct: 632 DHKTLELLNNI 642
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 71.3 bits (167), Expect = 8e-12
Identities = 68/292 (23%), Positives = 145/292 (49%), Gaps = 29/292 (9%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V KL VD ++ N + L L+ +PH+K +DL N I KL ++ +Q + L
Sbjct: 430 VLEKLTAVDKLCMSGNCVETLRLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLD 489
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLNTL-------------NGALRDLD------DL 109
+ DN++ +++ + ++ +H N+L TL + L LD L
Sbjct: 490 LRDNKLGDLDA-MIFNNIEVLHCERNQLVTLDICGYFLKALYASSNELVQLDVYPVPNYL 548
Query: 110 EWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL 169
++ ++ N L+++ E +++K++++ HN++ LP+ L SL+ L N + L
Sbjct: 549 SYMDVSRNRLENVP-EWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARL 607
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKS---L 226
E L+++ ++ + + N++ L + +A+ L L+ + N+L+ L + S ++ L
Sbjct: 608 PERLERT-SVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNSIL 666
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENLVDVE 274
+ L LT+N +T+ + + G L ++ +++N++ S LE L +++
Sbjct: 667 QELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEID 718
Score = 63.3 bits (147), Expect = 2e-09
Identities = 62/261 (23%), Positives = 125/261 (47%), Gaps = 15/261 (5%)
Query: 13 LDLVDYFSLA----DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
LD+ YF A N L +L + + + ++ +D+ RN++ + E + ++LE L
Sbjct: 519 LDICGYFLKALYASSNELVQLDVYPVPN--YLSYMDVSRNRLENVPEW-VCESRKLEVLD 575
Query: 69 VADNQISEIEKDAL-PKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
+ NQI E+ L+ + G N+L L L + +E + + N L + L
Sbjct: 576 IGHNQICELPARLFCNSSLRKLLAGHNQLARLPERL-ERTSVEVLDVQHNQLLELPPNLL 634
Query: 128 TKAKKMQLIHAAHNELQSLPS---DLKLMPSLQSLYFYGNNIKSLDETLQKSR-NLMRIG 183
KA ++ ++A+ N+L+SLP + LQ LY N++ L +L +
Sbjct: 635 MKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHPHLKILH 694
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQE 243
+++N+++ + E+L E+D++ N+LK + ++ + + + + H+ E E
Sbjct: 695 MAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTV-IAHSNCIEV-FPE 752
Query: 244 IKGLRRLSVIDLSHNQISLLT 264
+ L + +DLS N++S +T
Sbjct: 753 VMQLPEIKCVDLSCNELSEVT 773
Score = 55.6 bits (128), Expect = 4e-07
Identities = 66/252 (26%), Positives = 114/252 (45%), Gaps = 15/252 (5%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
F L N L LP L+++ + L L N+ T + E + ++ L ++ N + +
Sbjct: 394 FLLDGNFLQSLPAE-LENMKQLSYLGLSFNEFTDIPEV-LEKLTAVDKLCMSGNCVETLR 451
Query: 79 KDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQL 135
AL K +KHV L +N + L D L + + + N L ++ + +++
Sbjct: 452 LQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMI---FNNIEV 508
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+H N+L +L D+ L++LY N + LD L + +S N++E + +
Sbjct: 509 LHCERNQLVTL--DI-CGYFLKALYASSNELVQLD-VYPVPNYLSYMDVSRNRLENVP-E 563
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDL 255
E+ KL LDI +N++ L L SLR L HN + L E + V+D+
Sbjct: 564 WVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLAR--LPERLERTSVEVLDV 621
Query: 256 SHNQISLLTGSL 267
HNQ+ L +L
Sbjct: 622 QHNQLLELPPNL 633
Score = 55.2 bits (127), Expect = 6e-07
Identities = 50/214 (23%), Positives = 101/214 (47%), Gaps = 19/214 (8%)
Query: 62 QELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
Q+L HL + N + + +GL + KL +LN + L D +
Sbjct: 312 QDLTHLNLKQNFLRQNPSLPAARGLNELQR-FTKLKSLNLSNNHLGDFPLAVCS------ 364
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+PT A+ ++ + N L+S+P+ + +M +LQ+ GN ++SL L+ + L
Sbjct: 365 ----IPTLAE----LNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAELENMKQLSY 416
Query: 182 IGLSFNKIEFLTK--DDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+GLSFN+ + + + T +KL L+ +LR + +++++L N + +
Sbjct: 417 LGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETLRL--QALRKMPHIKHVDLRLNVIRKL 474
Query: 240 SLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDV 273
E+ L+ ++ +DL N++ L + N ++V
Sbjct: 475 IADEVDFLQHVTQLDLRDNKLGDLDAMIFNNIEV 508
Score = 36.3 bits (80), Expect = 0.29
Identities = 23/117 (19%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +NSL + +L PH+K L + N++ ++ELE + ++ N++ I
Sbjct: 671 LTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTT 730
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQL 135
+ H + + + + L +++ + ++ N L ++ LP K +++ L
Sbjct: 731 IMNCSRMHTVIAHSNCIEVFPEVMQLPEIKCVDLSCNELSEVTLPENLPPKLQELDL 787
Score = 34.7 bits (76), Expect = 0.87
Identities = 38/180 (21%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPH--VKTLDLCRNKITKLTEEDFRDIQ 62
L ++ K D + + + + N L LP L + ++ L L N +T
Sbjct: 629 LPPNLLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCVPLLTGHP 688
Query: 63 ELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L+ L +A N++ + K L+ + L NKL + + + + + ++N ++
Sbjct: 689 HLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAHSNCIE 748
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNL 179
+ + +++ + + NEL + L P LQ L GN LD +TL+ N+
Sbjct: 749 VFPEVM--QLPEIKCVDLSCNELSEVTLPENLPPKLQELDLTGNPRLVLDHKTLELLNNI 806
>BC130290-1|AAI30291.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/225 (26%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFIN 115
+ ++Q + + + NQ+ E + LPK ++ +HL N + T++ AL L LE + ++
Sbjct: 83 ELHNVQSVHTVYLYGNQLDEFPMN-LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLD 141
Query: 116 ANNLKSI--ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DET 172
N++ ++ E+ +A ++L+ + N L S+P L + LQ L N I + D
Sbjct: 142 DNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV--DLQELRVDENRIAVISDMA 199
Query: 173 LQKSRNLMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLN 230
Q +L R+ + N + + + + F+ KL E I N L + L +R L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIR-LY 258
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVE 274
L N + L LR+L +D+S+NQ+ +LT G +NL +++
Sbjct: 259 LQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLK 303
Score = 49.6 bits (113), Expect = 3e-05
Identities = 40/176 (22%), Positives = 85/176 (48%), Gaps = 10/176 (5%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIK 167
D +++ N +L S+ +P + L + N P++L + S+ ++Y YGN +
Sbjct: 43 DRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA-GFPAELHNVQSVHTVYLYGNQLD 101
Query: 168 SLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL---NGSLRSLK 224
L K N+ + L N I+ +++ + KL EL + N + + +G+ R
Sbjct: 102 EFPMNLPK--NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVDVETRVLE 279
SL+ L L+ N+++ + L+ L V N+I++++ + +NL +E +++
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRV---DENRIAVISDMAFQNLTSLERLIVD 212
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 31/220 (14%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIE 78
L +N++ + R L L ++ L L N I+ + ED FR+ L+ L ++ N +S +
Sbjct: 116 LQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP 175
Query: 79 KDALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNL--KSIENELPTKAKKMQL 135
LP L+ + + N++ ++ A ++L LE + ++ N L K I + K++
Sbjct: 176 V-GLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N L P DL +L+R+ L N+I +
Sbjct: 235 FSIVRNSLSHPPPDLP------------------------GTHLIRLYLQDNQINHIPLT 270
Query: 196 DFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
F+ KL LDI+ N+L+ L G +L +L+ L +N
Sbjct: 271 AFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310
>BC126249-1|AAI26250.1| 660|Homo sapiens fibronectin leucine rich
transmembrane protein 2 protein.
Length = 660
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/225 (26%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFIN 115
+ ++Q + + + NQ+ E + LPK ++ +HL N + T++ AL L LE + ++
Sbjct: 83 ELHNVQSVHTVYLYGNQLDEFPMN-LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLD 141
Query: 116 ANNLKSI--ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DET 172
N++ ++ E+ +A ++L+ + N L S+P L + LQ L N I + D
Sbjct: 142 DNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV--DLQELRVDENRIAVISDMA 199
Query: 173 LQKSRNLMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLN 230
Q +L R+ + N + + + + F+ KL E I N L + L +R L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIR-LY 258
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVE 274
L N + L LR+L +D+S+NQ+ +LT G +NL +++
Sbjct: 259 LQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLK 303
Score = 49.6 bits (113), Expect = 3e-05
Identities = 40/176 (22%), Positives = 85/176 (48%), Gaps = 10/176 (5%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIK 167
D +++ N +L S+ +P + L + N P++L + S+ ++Y YGN +
Sbjct: 43 DRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA-GFPAELHNVQSVHTVYLYGNQLD 101
Query: 168 SLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL---NGSLRSLK 224
L K N+ + L N I+ +++ + KL EL + N + + +G+ R
Sbjct: 102 EFPMNLPK--NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVDVETRVLE 279
SL+ L L+ N+++ + L+ L V N+I++++ + +NL +E +++
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRV---DENRIAVISDMAFQNLTSLERLIVD 212
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 31/220 (14%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIE 78
L +N++ + R L L ++ L L N I+ + ED FR+ L+ L ++ N +S +
Sbjct: 116 LQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP 175
Query: 79 KDALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNL--KSIENELPTKAKKMQL 135
LP L+ + + N++ ++ A ++L LE + ++ N L K I + K++
Sbjct: 176 V-GLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N L P DL +L+R+ L N+I +
Sbjct: 235 FSIVRNSLSHPPPDLP------------------------GTHLIRLYLQDNQINHIPLT 270
Query: 196 DFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
F+ KL LDI+ N+L+ L G +L +L+ L +N
Sbjct: 271 AFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310
>AY358287-1|AAQ88654.1| 660|Homo sapiens FLRT2 protein.
Length = 660
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/225 (26%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFIN 115
+ ++Q + + + NQ+ E + LPK ++ +HL N + T++ AL L LE + ++
Sbjct: 83 ELHNVQSVHTVYLYGNQLDEFPMN-LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLD 141
Query: 116 ANNLKSI--ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DET 172
N++ ++ E+ +A ++L+ + N L S+P L + LQ L N I + D
Sbjct: 142 DNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV--DLQELRVDENRIAVISDMA 199
Query: 173 LQKSRNLMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLN 230
Q +L R+ + N + + + + F+ KL E I N L + L +R L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIR-LY 258
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVE 274
L N + L LR+L +D+S+NQ+ +LT G +NL +++
Sbjct: 259 LQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLK 303
Score = 49.6 bits (113), Expect = 3e-05
Identities = 40/176 (22%), Positives = 85/176 (48%), Gaps = 10/176 (5%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIK 167
D +++ N +L S+ +P + L + N P++L + S+ ++Y YGN +
Sbjct: 43 DRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA-GFPAELHNVQSVHTVYLYGNQLD 101
Query: 168 SLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL---NGSLRSLK 224
L K N+ + L N I+ +++ + KL EL + N + + +G+ R
Sbjct: 102 EFPMNLPK--NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVDVETRVLE 279
SL+ L L+ N+++ + L+ L V N+I++++ + +NL +E +++
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRV---DENRIAVISDMAFQNLTSLERLIVD 212
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 31/220 (14%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIE 78
L +N++ + R L L ++ L L N I+ + ED FR+ L+ L ++ N +S +
Sbjct: 116 LQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP 175
Query: 79 KDALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNL--KSIENELPTKAKKMQL 135
LP L+ + + N++ ++ A ++L LE + ++ N L K I + K++
Sbjct: 176 V-GLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N L P DL +L+R+ L N+I +
Sbjct: 235 FSIVRNSLSHPPPDLP------------------------GTHLIRLYLQDNQINHIPLT 270
Query: 196 DFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
F+ KL LDI+ N+L+ L G +L +L+ L +N
Sbjct: 271 AFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310
>AF169676-1|AAF28460.1| 660|Homo sapiens leucine-rich repeat
transmembrane protein FLRT2 protein.
Length = 660
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/225 (26%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFIN 115
+ ++Q + + + NQ+ E + LPK ++ +HL N + T++ AL L LE + ++
Sbjct: 83 ELHNVQSVHTVYLYGNQLDEFPMN-LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLD 141
Query: 116 ANNLKSI--ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DET 172
N++ ++ E+ +A ++L+ + N L S+P L + LQ L N I + D
Sbjct: 142 DNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV--DLQELRVDENRIAVISDMA 199
Query: 173 LQKSRNLMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLN 230
Q +L R+ + N + + + + F+ KL E I N L + L +R L
Sbjct: 200 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIR-LY 258
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVE 274
L N + L LR+L +D+S+NQ+ +LT G +NL +++
Sbjct: 259 LQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLK 303
Score = 49.6 bits (113), Expect = 3e-05
Identities = 40/176 (22%), Positives = 85/176 (48%), Gaps = 10/176 (5%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIK 167
D +++ N +L S+ +P + L + N P++L + S+ ++Y YGN +
Sbjct: 43 DRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA-GFPAELHNVQSVHTVYLYGNQLD 101
Query: 168 SLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL---NGSLRSLK 224
L K N+ + L N I+ +++ + KL EL + N + + +G+ R
Sbjct: 102 EFPMNLPK--NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 159
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVDVETRVLE 279
SL+ L L+ N+++ + L+ L V N+I++++ + +NL +E +++
Sbjct: 160 SLKLLFLSKNHLSSVPVGLPVDLQELRV---DENRIAVISDMAFQNLTSLERLIVD 212
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 31/220 (14%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIE 78
L +N++ + R L L ++ L L N I+ + ED FR+ L+ L ++ N +S +
Sbjct: 116 LQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP 175
Query: 79 KDALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNL--KSIENELPTKAKKMQL 135
LP L+ + + N++ ++ A ++L LE + ++ N L K I + K++
Sbjct: 176 V-GLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N L P DL +L+R+ L N+I +
Sbjct: 235 FSIVRNSLSHPPPDLP------------------------GTHLIRLYLQDNQINHIPLT 270
Query: 196 DFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
F+ KL LDI+ N+L+ L G +L +L+ L +N
Sbjct: 271 AFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 310
>AB007865-1|BAA23701.2| 706|Homo sapiens KIAA0405 protein.
Length = 706
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/225 (26%), Positives = 111/225 (49%), Gaps = 11/225 (4%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFIN 115
+ ++Q + + + NQ+ E + LPK ++ +HL N + T++ AL L LE + ++
Sbjct: 129 ELHNVQSVHTVYLYGNQLDEFPMN-LPKNVRVLHLQENNIQTISRAALAQLLKLEELHLD 187
Query: 116 ANNLKSI--ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DET 172
N++ ++ E+ +A ++L+ + N L S+P L + LQ L N I + D
Sbjct: 188 DNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPV--DLQELRVDENRIAVISDMA 245
Query: 173 LQKSRNLMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLN 230
Q +L R+ + N + + + + F+ KL E I N L + L +R L
Sbjct: 246 FQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIR-LY 304
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVE 274
L N + L LR+L +D+S+NQ+ +LT G +NL +++
Sbjct: 305 LQDNQINHIPLTAFSNLRKLERLDISNNQLRMLTQGVFDNLSNLK 349
Score = 49.6 bits (113), Expect = 3e-05
Identities = 40/176 (22%), Positives = 85/176 (48%), Gaps = 10/176 (5%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIK 167
D +++ N +L S+ +P + L + N P++L + S+ ++Y YGN +
Sbjct: 89 DRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINNA-GFPAELHNVQSVHTVYLYGNQLD 147
Query: 168 SLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL---NGSLRSLK 224
L K N+ + L N I+ +++ + KL EL + N + + +G+ R
Sbjct: 148 EFPMNLPK--NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAI 205
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVDVETRVLE 279
SL+ L L+ N+++ + L+ L V N+I++++ + +NL +E +++
Sbjct: 206 SLKLLFLSKNHLSSVPVGLPVDLQELRV---DENRIAVISDMAFQNLTSLERLIVD 258
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 31/220 (14%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIE 78
L +N++ + R L L ++ L L N I+ + ED FR+ L+ L ++ N +S +
Sbjct: 162 LQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVP 221
Query: 79 KDALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNL--KSIENELPTKAKKMQL 135
LP L+ + + N++ ++ A ++L LE + ++ N L K I + K++
Sbjct: 222 V-GLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 280
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
N L P DL +L+R+ L N+I +
Sbjct: 281 FSIVRNSLSHPPPDLP------------------------GTHLIRLYLQDNQINHIPLT 316
Query: 196 DFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHN 234
F+ KL LDI+ N+L+ L G +L +L+ L +N
Sbjct: 317 AFSNLRKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNN 356
>X75546-1|CAA53233.1| 376|Homo sapiens fibromodulin protein.
Length = 376
Score = 70.1 bits (164), Expect = 2e-11
Identities = 61/255 (23%), Positives = 128/255 (50%), Gaps = 20/255 (7%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKIT--KLTEEDFRDIQELEHLLVADNQIS 75
Y +N + + V + + + L N+IT K+ + F ++ LE L + N ++
Sbjct: 109 YVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLT 168
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQ 134
+ LP+ L+ +HL N+++ + N AL L++L +++ + ++ + + + + +
Sbjct: 169 RMP-GPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHDEIQEVGSSM-RGLRSLI 226
Query: 135 LIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI--EF 191
L+ ++N L+ +P L +L+ LY NN+ ++ D + + L+ + LS N +
Sbjct: 227 LLDLSYNHLRKVPDGLP--SALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNG 284
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ------EIK 245
L + F + L ELD++YN+L+ + +L++L YL N + EFS+ ++
Sbjct: 285 LASNTFNSSS-LLELDLSYNQLQKIPPVNTNLENL-YLQ--GNRINEFSISSFCTVVDVV 340
Query: 246 GLRRLSVIDLSHNQI 260
+L V+ L N+I
Sbjct: 341 NFSKLQVVRLDGNEI 355
Score = 60.9 bits (141), Expect = 1e-08
Identities = 52/210 (24%), Positives = 99/210 (47%), Gaps = 11/210 (5%)
Query: 82 LPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHA 138
+P +K+V+ N++ ++ G + L WI ++ N + S + ++ +K + ++ ++
Sbjct: 103 VPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYL 162
Query: 139 AHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDF 197
HN L +P L SL+ L+ N I + + L+ NL + L ++I+ +
Sbjct: 163 DHNNLTRMPGPLPR--SLRELHLDHNQISRVPNNALEGLENLTALYLQHDEIQEVGSS-M 219
Query: 198 TEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN L+ + L S +L L + HN + +G +L + LSH
Sbjct: 220 RGLRSLILLDLSYNHLRKVPDGLPS--ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSH 277
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHI 287
N SL L + + +LEL L +N +
Sbjct: 278 N--SLTNNGLASNTFNSSSLLELDLSYNQL 305
Score = 51.6 bits (118), Expect = 7e-06
Identities = 46/193 (23%), Positives = 98/193 (50%), Gaps = 13/193 (6%)
Query: 5 LKESVFTKLDLVDYFSLADNSLP--ELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQ 62
++E VF + + +L N + ++ R V L H++ L L N +T++ R ++
Sbjct: 120 IQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLR 179
Query: 63 ELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
EL HL NQIS + +AL + L ++L +++ + ++R L L + ++ N+L+
Sbjct: 180 EL-HL--DHNQISRVPNNALEGLENLTALYLQHDEIQEVGSSMRGLRSLILLDLSYNHLR 236
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNI--KSLDETLQKSR 177
+ + LP+ ++ ++ HN + ++P S + P L + N++ L S
Sbjct: 237 KVPDGLPS---ALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSS 293
Query: 178 NLMRIGLSFNKIE 190
+L+ + LS+N+++
Sbjct: 294 SLLELDLSYNQLQ 306
Score = 40.3 bits (90), Expect = 0.018
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 14/138 (10%)
Query: 247 LRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHIFXX-XXXXXXXXXXXXXXX 305
LR L + L HN ++ + G L + EL LDHN I
Sbjct: 154 LRHLERLYLDHNNLTRMPGPLPR------SLRELHLDHNQISRVPNNALEGLENLTALYL 207
Query: 306 XXXXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPS-LEELIAHHNNI-TVLDK 363
IQ++ +SYNH+ + + LPS LE+L HNN+ TV D
Sbjct: 208 QHDEIQEVGSSMRGLRSLILLD-LSYNHLRKVPDG----LPSALEQLYMEHNNVYTVPDS 262
Query: 364 DFHGLPSLCSADLSFNKI 381
F G P L LS N +
Sbjct: 263 YFRGAPKLLYVRLSHNSL 280
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 187 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 244
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 245 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 305 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 364 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 44 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 101
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 102 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 161
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 162 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 221 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 278
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 279 LLKKLTTLKVDDNQLTMLPNTIGNL 303
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 161 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 221 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 279
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 280 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 339 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 380
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 233 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 290
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 349
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 350 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 409
Query: 191 FL 192
L
Sbjct: 410 AL 411
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 182 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 239
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 240 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 300 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 359 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 39 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 96
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 97 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 157 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 216 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 274 LLKKLTTLKVDDNQLTMLPNTIGNL 298
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 156 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 216 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 274
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 275 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 334 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 375
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 228 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 285
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 344
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 345 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 404
Query: 191 FL 192
L
Sbjct: 405 AL 406
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 187 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 244
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 245 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 305 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 364 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 44 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 101
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 102 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 161
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 162 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 221 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 278
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 279 LLKKLTTLKVDDNQLTMLPNTIGNL 303
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 161 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 221 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 279
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 280 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 339 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 380
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 233 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 290
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 349
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 350 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 409
Query: 191 FL 192
L
Sbjct: 410 AL 411
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 182 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 239
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 240 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 300 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 359 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 39 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 96
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 97 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 157 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 216 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 274 LLKKLTTLKVDDNQLTMLPNTIGNL 298
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 156 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 216 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 274
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 275 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 334 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 375
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 228 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 285
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 344
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 345 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 404
Query: 191 FL 192
L
Sbjct: 405 AL 406
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 187 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 244
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 245 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 305 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 364 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 44 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 101
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 102 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 161
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 162 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 221 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 278
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 279 LLKKLTTLKVDDNQLTMLPNTIGNL 303
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 161 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 221 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 279
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 280 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 339 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 380
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 233 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 290
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 349
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 350 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 409
Query: 191 FL 192
L
Sbjct: 410 AL 411
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 182 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 239
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 240 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 300 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 359 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 39 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 96
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 97 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 157 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 216 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 274 LLKKLTTLKVDDNQLTMLPNTIGNL 298
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 156 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 216 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 274
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 275 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 334 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 375
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 228 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 285
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 344
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 345 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 404
Query: 191 FL 192
L
Sbjct: 405 AL 406
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 187 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 244
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 245 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 305 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 364 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 44 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 101
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 102 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 161
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 162 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 221 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 278
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 279 LLKKLTTLKVDDNQLTMLPNTIGNL 303
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 161 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 221 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 279
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 280 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 339 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 380
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 233 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 290
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 349
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 350 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 409
Query: 191 FL 192
L
Sbjct: 410 AL 411
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 182 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 239
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 240 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 300 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 359 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 39 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 96
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 97 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 157 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 216 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 274 LLKKLTTLKVDDNQLTMLPNTIGNL 298
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 156 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 216 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 274
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 275 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 334 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 375
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 228 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 285
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 344
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 345 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 404
Query: 191 FL 192
L
Sbjct: 405 AL 406
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 187 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 244
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 245 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 304
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 305 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 364 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 406
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 44 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 101
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 102 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 161
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 162 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 221 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 278
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 279 LLKKLTTLKVDDNQLTMLPNTIGNL 303
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 161 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 220
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 221 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 279
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 280 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 338
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 339 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 380
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 233 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 290
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 291 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 349
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 350 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 409
Query: 191 FL 192
L
Sbjct: 410 AL 411
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 70.1 bits (164), Expect = 2e-11
Identities = 60/224 (26%), Positives = 110/224 (49%), Gaps = 5/224 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ L +N ELP VL + +++ L + N + L ++ L +L ++
Sbjct: 182 KLAQLERLDLGNNEFGELPE-VLDQIQNLRELWMDNNALQVLPGS-IGKLKMLVYLDMSK 239
Query: 72 NQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
N+I ++ D + L+ + L N L L ++ L L + ++ N L + N + +
Sbjct: 240 NRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLS 299
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
++ + NEL+SLPS + + SL++L N + L + +N+ + L NK+E
Sbjct: 300 L-LEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Query: 191 FLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
FL ++ + +KL L+++ N LK L S LK L L L+ N
Sbjct: 359 FL-PEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDN 401
Score = 64.5 bits (150), Expect = 9e-10
Identities = 54/265 (20%), Positives = 121/265 (45%), Gaps = 6/265 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
+ VF ++ L N + ELP+ + + ++ L + N ++ L + L+
Sbjct: 39 KEVFNFERTLEELYLDANQIEELPKQLF-NCQALRKLSIPDNDLSNLPTT-IASLVNLKE 96
Query: 67 LLVADNQISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENE 125
L ++ N + E E K L + +N ++ L L +L +++N L+ +
Sbjct: 97 LDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPAN 156
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ K++++ N L++LP + + L+ L N L E L + +NL + +
Sbjct: 157 FG-RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 186 FNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N ++ L + + L LD++ N ++ ++ + ++L L L+ N + + I
Sbjct: 216 NNALQVL-PGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLP-DSIG 273
Query: 246 GLRRLSVIDLSHNQISLLTGSLENL 270
L++L+ + + NQ+++L ++ NL
Sbjct: 274 LLKKLTTLKVDDNQLTMLPNTIGNL 298
Score = 59.7 bits (138), Expect = 3e-08
Identities = 49/225 (21%), Positives = 106/225 (47%), Gaps = 6/225 (2%)
Query: 57 DFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGINKLNTLNGALRDLDDLEWIFIN 115
+F + +L L + +N + + K L+ + LG N+ L L + +L ++++
Sbjct: 156 NFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMD 215
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
N L+ + + K K + + + N ++++ D+ +L+ L N ++ L +++
Sbjct: 216 NNALQVLPGSIG-KLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGL 274
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNY 235
+ L + + N++ L + L E D + NEL+ L ++ L SLR L + N+
Sbjct: 275 LKKLTTLKVDDNQLTMLP-NTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENF 333
Query: 236 MTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLEL 280
+ E +EI + ++V+ L N++ L + + + RVL L
Sbjct: 334 LPELP-REIGSCKNVTVMSLRSNKLEFLPEEIGQM--QKLRVLNL 375
Score = 43.6 bits (98), Expect = 0.002
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 4/182 (2%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KL ++ Y ++ N + + + ++ L L N + +L + +++L L V D
Sbjct: 228 KLKMLVYLDMSKNRIETVDMDI-SGCEALEDLLLSSNMLQQLPDS-IGLLKKLTTLKVDD 285
Query: 72 NQISEIEKDALPKGL-KHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKA 130
NQ++ + L + N+L +L + L L + ++ N L + E+ +
Sbjct: 286 NQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGS-C 344
Query: 131 KKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIE 190
K + ++ N+L+ LP ++ M L+ L N +K+L + K + L + LS N+ +
Sbjct: 345 KNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSK 404
Query: 191 FL 192
L
Sbjct: 405 AL 406
>BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like
family peptide receptor 1 protein.
Length = 757
Score = 69.7 bits (163), Expect = 3e-11
Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 25/250 (10%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
V SL N + +LP ++ ++ L L NKIT ++ FR + L L ++ N+I+
Sbjct: 128 VTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRIT 187
Query: 76 EIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
++ G DL LEW+ I N+L I + L
Sbjct: 188 FLKP---------------------GVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 226
Query: 136 IHAAHNELQSLPSD--LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFL 192
+ +N L LP + MP L L GN+I +L + T NL + + NKI L
Sbjct: 227 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHL 286
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
++ F +KL ELD+ N+++ L + + LK L LNL++N + + + L +L
Sbjct: 287 NENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLK 346
Query: 252 VIDLSHNQIS 261
+ L +IS
Sbjct: 347 SLSLEGIEIS 356
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/226 (23%), Positives = 97/226 (42%), Gaps = 12/226 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 217 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 275
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKIEFLT 193
+ N++ L + + L L N I++L + K + L ++ LS+N I+ +
Sbjct: 276 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Query: 194 KDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ F KL L + E+ N R + L +NL+H Y +F
Sbjct: 336 ANQFDYLVKLKSLSLEGIEIS--NIQQRMFRPL--MNLSHIYFKKF 377
Score = 39.1 bits (87), Expect = 0.041
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 8/193 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDF-RDIQE 63
LK VF L +++ + DN L + L + L L N +T+L ++ + +
Sbjct: 189 LKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPR 248
Query: 64 LEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLK 120
L L + N I + L + + NK+N LN L L+ + + +N ++
Sbjct: 249 LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIE 308
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
++ + K++ ++ ++N +Q + ++ + L+SL G I ++ + + R L
Sbjct: 309 NLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRM--FRPL 366
Query: 180 MRIG-LSFNKIEF 191
M + + F K ++
Sbjct: 367 MNLSHIYFKKFQY 379
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 147 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 206
>BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 69.7 bits (163), Expect = 3e-11
Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 25/250 (10%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
V SL N + +LP ++ ++ L L NKIT ++ FR + L L ++ N+I+
Sbjct: 128 VTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRIT 187
Query: 76 EIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
++ G DL LEW+ I N+L I + L
Sbjct: 188 FLKP---------------------GVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 226
Query: 136 IHAAHNELQSLPSD--LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFL 192
+ +N L LP + MP L L GN+I +L + T NL + + NKI L
Sbjct: 227 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHL 286
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
++ F +KL ELD+ N+++ L + + LK L LNL++N + + + L +L
Sbjct: 287 NENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLK 346
Query: 252 VIDLSHNQIS 261
+ L +IS
Sbjct: 347 SLSLEGIEIS 356
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/226 (23%), Positives = 97/226 (42%), Gaps = 12/226 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 217 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 275
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKIEFLT 193
+ N++ L + + L L N I++L + K + L ++ LS+N I+ +
Sbjct: 276 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Query: 194 KDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ F KL L + E+ N R + L +NL+H Y +F
Sbjct: 336 ANQFDYLVKLKSLSLEGIEIS--NIQQRMFRPL--MNLSHIYFKKF 377
Score = 39.1 bits (87), Expect = 0.041
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 8/193 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDF-RDIQE 63
LK VF L +++ + DN L + L + L L N +T+L ++ + +
Sbjct: 189 LKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPR 248
Query: 64 LEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLK 120
L L + N I + L + + NK+N LN L L+ + + +N ++
Sbjct: 249 LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIE 308
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
++ + K++ ++ ++N +Q + ++ + L+SL G I ++ + + R L
Sbjct: 309 NLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRM--FRPL 366
Query: 180 MRIG-LSFNKIEF 191
M + + F K ++
Sbjct: 367 MNLSHIYFKKFQY 379
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 147 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 206
>BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein.
Length = 677
Score = 69.7 bits (163), Expect = 3e-11
Identities = 71/276 (25%), Positives = 125/276 (45%), Gaps = 14/276 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIE 78
L NS+ +P LP+++ LDL +N IT + + F+ +++L + N + +I
Sbjct: 328 LTGNSIASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRSNMDGNNLIQIP 387
Query: 79 KDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE-NELPTK-AKKMQL 135
LP L+ + + N L ++ +L DL+ L + + NNL N L K K +
Sbjct: 388 SQ-LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAY 446
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIE--FL 192
+ N+ + +P L S++ LY N I+ + E +R + I L +NKIE +
Sbjct: 447 LRLGKNKFRIIPQGLP--GSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRI 504
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLR-RLS 251
+ E L +D++YN+L ++ L KSL +L L N + + L
Sbjct: 505 APLAWINQENLESIDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLE 562
Query: 252 VIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+ LS N+++ + + EL LDHN +
Sbjct: 563 YLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDL 598
Score = 51.2 bits (117), Expect = 9e-06
Identities = 55/234 (23%), Positives = 109/234 (46%), Gaps = 17/234 (7%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEED--FRDIQELEHLLVADNQISEIEKD 80
+N+L + L L + TL+L N +++ F+ ++ L +L + N+ I +
Sbjct: 401 ENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQ- 459
Query: 81 ALPKGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKA----KKMQL 135
LP ++ ++L N++ + + I + N ++ EN + A + ++
Sbjct: 460 GLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIE--ENRIAPLAWINQENLES 517
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKI--EF 191
I ++N+L +PS L SL L GN I+ + + L + LSFNK+ +
Sbjct: 518 IDLSYNKLYHVPSYLP--KSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLADDG 575
Query: 192 LTKDDFTEA-EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEI 244
+ + F A L EL + +N+LK + ++ +K+L +L L +N + +EI
Sbjct: 576 MDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 629
>BC044233-1|AAH44233.1| 692|Homo sapiens leucine rich repeat
containing 33 protein.
Length = 692
Score = 69.7 bits (163), Expect = 3e-11
Identities = 69/256 (26%), Positives = 124/256 (48%), Gaps = 16/256 (6%)
Query: 21 LADNSLPE-LPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L+ N+L E + +LQ+L ++++ L N I +L + F ++ L L + N I EIE
Sbjct: 139 LSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEG 198
Query: 80 DALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L+H++L N L + L L + ++ N L+ A +++ +
Sbjct: 199 GAFDGLAELRHLNLAFNNLPCIVDF--GLTRLRVLNVSYNVLEWFLATGGEAAFELETLD 256
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNI---KSLDETLQKSRNLMRIGLSFNKIEFLTK 194
+HN+L P L L++L NN+ + L T + + L + +T
Sbjct: 257 LSHNQLLFFPL-LPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNVTNITT 315
Query: 195 ----DDFTEAE--KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGL 247
++F+ ++ L LD++ N+ +YL +G LR + SL +LNL N + ++E +
Sbjct: 316 VSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPP 375
Query: 248 RRLSVIDLSHNQISLL 263
L+ +DLSHNQ+S L
Sbjct: 376 GALTELDLSHNQLSEL 391
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN---GSLRSLKSL 226
D L+K +L + L N + L + L ELD+++N+L L+ G L SL
Sbjct: 345 DGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQLSELHLAPGLASCLGSL 404
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
R NL+ N + R ++ +D+SHNQISL
Sbjct: 405 RLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISL 440
Score = 44.8 bits (101), Expect = 8e-04
Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N L L H LQ P +++L L + +++ F++ L L++ DN +SE +
Sbjct: 63 TLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSENYE 122
Query: 80 D------ALPKGLKHVHLGINKLNTLNGA--LRDLDDLEWIFINANNLKSIENELPTKAK 131
+ ALP GL+ + L N L A L++L L + + N + +++ + +
Sbjct: 123 ETAAALHALP-GLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLE 181
Query: 132 KMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+++ + N + + + L+ L NN+ + D L + R L +S+N +
Sbjct: 182 RLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVL---NVSYNVL 238
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
E+ A +L LD+++N+L + L LR L L N M
Sbjct: 239 EWFLATGGEAAFELETLDLSHNQLLFF-PLLPQYSKLRTLLLRDNNM 284
Score = 37.9 bits (84), Expect = 0.094
Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 18/262 (6%)
Query: 10 FTKLDLVD--YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL 67
F+ DL D + ++ N LP L+ +P + L+L +N + L + L L
Sbjct: 322 FSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTEL 381
Query: 68 LVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ NQ+SE+ L GL + N + L L +F NA N+ ++ ++
Sbjct: 382 DLSHNQLSELH---LAPGLASCLGSLRLFNLSSNQL--LGVPPGLFANARNITTL--DMS 434
Query: 128 TKAKKMQLIHAAHNELQSLPS--DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ + AA + + PS D + M SL+SL G + +L + + +L + LS
Sbjct: 435 HNQISLCPLPAASDRV-GPPSCVDFRNMASLRSLSLEGCGLGALPDCPFQGTSLTYLDLS 493
Query: 186 FN----KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
N D ++ L ++ +LR L+L+ N +T F
Sbjct: 494 SNWGVLNGSLAPLQDVAPMLQVLSLRNMGLHSSFMALDFSGFGNLRDLDLSGNCLTTF-- 551
Query: 242 QEIKGLRRLSVIDLSHNQISLL 263
G L +DL N ++ L
Sbjct: 552 PRFGGSLALETLDLRRNSLTAL 573
Score = 33.5 bits (73), Expect = 2.0
Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Query: 118 NLKSIENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLDE-TLQK 175
+L S+ + LP A+ + L N L++L + L+ P L+SL + +++ + Q+
Sbjct: 47 SLASVPSSLPPHARMLTL---DANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQE 103
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLA---ELDIAYNELKYLNGSL--RSLKSLRYLN 230
+L + L N + ++ L LD++ N L +L ++L SLR ++
Sbjct: 104 QGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVS 163
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
L N + +GL RL +DL N I + G
Sbjct: 164 LAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEG 198
>AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein.
Length = 724
Score = 69.7 bits (163), Expect = 3e-11
Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 25/250 (10%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
V SL N + +LP ++ ++ L L NKIT ++ FR + L L ++ N+I+
Sbjct: 95 VTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRIT 154
Query: 76 EIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
++ G DL LEW+ I N+L I + L
Sbjct: 155 FLKP---------------------GVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 193
Query: 136 IHAAHNELQSLPSD--LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFL 192
+ +N L LP + MP L L GN+I +L + T NL + + NKI L
Sbjct: 194 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHL 253
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
++ F +KL ELD+ N+++ L + + LK L LNL++N + + + L +L
Sbjct: 254 NENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLK 313
Query: 252 VIDLSHNQIS 261
+ L +IS
Sbjct: 314 SLSLEGIEIS 323
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/226 (23%), Positives = 97/226 (42%), Gaps = 12/226 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 124 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 183
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 184 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 242
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKIEFLT 193
+ N++ L + + L L N I++L + K + L ++ LS+N I+ +
Sbjct: 243 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 302
Query: 194 KDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ F KL L + E+ N R + L +NL+H Y +F
Sbjct: 303 ANQFDYLVKLKSLSLEGIEIS--NIQQRMFRPL--MNLSHIYFKKF 344
Score = 39.1 bits (87), Expect = 0.041
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 8/193 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDF-RDIQE 63
LK VF L +++ + DN L + L + L L N +T+L ++ + +
Sbjct: 156 LKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPR 215
Query: 64 LEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLK 120
L L + N I + L + + NK+N LN L L+ + + +N ++
Sbjct: 216 LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIE 275
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
++ + K++ ++ ++N +Q + ++ + L+SL G I ++ + + R L
Sbjct: 276 NLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRM--FRPL 333
Query: 180 MRIG-LSFNKIEF 191
M + + F K ++
Sbjct: 334 MNLSHIYFKKFQY 346
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 114 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 173
>AY358322-1|AAQ88688.1| 692|Homo sapiens ELLP3030 protein.
Length = 692
Score = 69.7 bits (163), Expect = 3e-11
Identities = 69/256 (26%), Positives = 124/256 (48%), Gaps = 16/256 (6%)
Query: 21 LADNSLPE-LPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
L+ N+L E + +LQ+L ++++ L N I +L + F ++ L L + N I EIE
Sbjct: 139 LSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEG 198
Query: 80 DALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L+H++L N L + L L + ++ N L+ A +++ +
Sbjct: 199 GAFDGLAELRHLNLAFNNLPCIVDF--GLTRLRVLNVSYNVLEWFLATGGEAAFELETLD 256
Query: 138 AAHNELQSLPSDLKLMPSLQSLYFYGNNI---KSLDETLQKSRNLMRIGLSFNKIEFLTK 194
+HN+L P L L++L NN+ + L T + + L + +T
Sbjct: 257 LSHNQLLFFPL-LPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMVAQFLLVDGNVTNITT 315
Query: 195 ----DDFTEAE--KLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGL 247
++F+ ++ L LD++ N+ +YL +G LR + SL +LNL N + ++E +
Sbjct: 316 VSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPP 375
Query: 248 RRLSVIDLSHNQISLL 263
L+ +DLSHNQ+S L
Sbjct: 376 GALTELDLSHNQLSEL 391
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/96 (32%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 170 DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN---GSLRSLKSL 226
D L+K +L + L N + L + L ELD+++N+L L+ G L SL
Sbjct: 345 DGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQLSELHLAPGLASCLGSL 404
Query: 227 RYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
R NL+ N + R ++ +D+SHNQISL
Sbjct: 405 RLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISL 440
Score = 44.8 bits (101), Expect = 8e-04
Identities = 55/227 (24%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
+L N L L H LQ P +++L L + +++ F++ L L++ DN +SE +
Sbjct: 63 TLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSENYE 122
Query: 80 D------ALPKGLKHVHLGINKLNTLNGA--LRDLDDLEWIFINANNLKSIENELPTKAK 131
+ ALP GL+ + L N L A L++L L + + N + +++ + +
Sbjct: 123 ETAAALHALP-GLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLE 181
Query: 132 KMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKI 189
+++ + N + + + L+ L NN+ + D L + R L +S+N +
Sbjct: 182 RLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVL---NVSYNVL 238
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYM 236
E+ A +L LD+++N+L + L LR L L N M
Sbjct: 239 EWFLATGGEAAFELETLDLSHNQLLFF-PLLPQYSKLRTLLLRDNNM 284
Score = 37.9 bits (84), Expect = 0.094
Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 18/262 (6%)
Query: 10 FTKLDLVD--YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL 67
F+ DL D + ++ N LP L+ +P + L+L +N + L + L L
Sbjct: 322 FSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTEL 381
Query: 68 LVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELP 127
++ NQ+SE+ L GL + N + L L +F NA N+ ++ ++
Sbjct: 382 DLSHNQLSELH---LAPGLASCLGSLRLFNLSSNQL--LGVPPGLFANARNITTL--DMS 434
Query: 128 TKAKKMQLIHAAHNELQSLPS--DLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLS 185
+ + AA + + PS D + M SL+SL G + +L + + +L + LS
Sbjct: 435 HNQISLCPLPAASDRV-GPPSCVDFRNMASLRSLSLEGCGLGALPDCPFQGTSLTYLDLS 493
Query: 186 FN----KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
N D ++ L ++ +LR L+L+ N +T F
Sbjct: 494 SNWGVLNGSLAPLQDVAPMLQVLSLRNMGLHSSFMALDFSGFGNLRDLDLSGNCLTTF-- 551
Query: 242 QEIKGLRRLSVIDLSHNQISLL 263
G L +DL N ++ L
Sbjct: 552 PRFGGSLALETLDLRRNSLTAL 573
Score = 33.5 bits (73), Expect = 2.0
Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Query: 118 NLKSIENELPTKAKKMQLIHAAHNELQSLPS-DLKLMPSLQSLYFYGNNIKSLDE-TLQK 175
+L S+ + LP A+ + L N L++L + L+ P L+SL + +++ + Q+
Sbjct: 47 SLASVPSSLPPHARMLTL---DANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQE 103
Query: 176 SRNLMRIGLSFNKIEFLTKDDFTEAEKLA---ELDIAYNELKYLNGSL--RSLKSLRYLN 230
+L + L N + ++ L LD++ N L +L ++L SLR ++
Sbjct: 104 QGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVS 163
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG 265
L N + +GL RL +DL N I + G
Sbjct: 164 LAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEG 198
>AK027100-1|BAB15657.1| 363|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23447 fis, clone HSI03346. ).
Length = 363
Score = 69.7 bits (163), Expect = 3e-11
Identities = 74/271 (27%), Positives = 123/271 (45%), Gaps = 36/271 (13%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITK--LTEEDFRDIQELEHLLVADNQISEIEKD 80
+N + ++PR L ++ L L N++T L F + LE+L ++ NQ++ +
Sbjct: 76 NNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA- 134
Query: 81 ALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
LP+ L +HLG N++ + A L L ++ + N L S + LP A
Sbjct: 135 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGS--SGLPAGA--------- 183
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTE 199
L+ + L +L+ YGN + + L R L + L N + L D
Sbjct: 184 ----------LRPLRGLHTLHLYGNGLDRVPPAL--PRRLRALVLPHNHVAALGARDLVA 231
Query: 200 AEKLAELDIAYNEL---KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLS 256
L EL++AYN L + + + R L++LR L+L N +T + GLR L L
Sbjct: 232 TPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTL---QLQ 288
Query: 257 HNQISLLTGSLENLVDVETRVLELRLDHNHI 287
NQ+ +L E L ++ ++ EL L HN +
Sbjct: 289 RNQLRML--EPEPLAGLD-QLRELSLAHNRL 316
>AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 7 protein.
Length = 757
Score = 69.7 bits (163), Expect = 3e-11
Identities = 68/250 (27%), Positives = 111/250 (44%), Gaps = 25/250 (10%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
V SL N + +LP ++ ++ L L NKIT ++ FR + L L ++ N+I+
Sbjct: 128 VTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRIT 187
Query: 76 EIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
++ G DL LEW+ I N+L I + L
Sbjct: 188 FLKP---------------------GVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLIL 226
Query: 136 IHAAHNELQSLPSD--LKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFL 192
+ +N L LP + MP L L GN+I +L + T NL + + NKI L
Sbjct: 227 LVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHL 286
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLS 251
++ F +KL ELD+ N+++ L + + LK L LNL++N + + + L +L
Sbjct: 287 NENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLK 346
Query: 252 VIDLSHNQIS 261
+ L +IS
Sbjct: 347 SLSLEGIEIS 356
Score = 57.6 bits (133), Expect = 1e-07
Identities = 53/226 (23%), Positives = 97/226 (42%), Gaps = 12/226 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 217 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 275
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKIEFLT 193
+ N++ L + + L L N I++L + K + L ++ LS+N I+ +
Sbjct: 276 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQ 335
Query: 194 KDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ F KL L + E+ N R + L +NL+H Y +F
Sbjct: 336 ANQFDYLVKLKSLSLEGIEIS--NIQQRMFRPL--MNLSHIYFKKF 377
Score = 39.1 bits (87), Expect = 0.041
Identities = 40/193 (20%), Positives = 86/193 (44%), Gaps = 8/193 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDF-RDIQE 63
LK VF L +++ + DN L + L + L L N +T+L ++ + +
Sbjct: 189 LKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPR 248
Query: 64 LEHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLK 120
L L + N I + L + + NK+N LN L L+ + + +N ++
Sbjct: 249 LHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIE 308
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNL 179
++ + K++ ++ ++N +Q + ++ + L+SL G I ++ + + R L
Sbjct: 309 NLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRM--FRPL 366
Query: 180 MRIG-LSFNKIEF 191
M + + F K ++
Sbjct: 367 MNLSHIYFKKFQY 379
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 147 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 206
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 69.7 bits (163), Expect = 3e-11
Identities = 73/278 (26%), Positives = 140/278 (50%), Gaps = 29/278 (10%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
V+ KL ++D +A N L L VL + H+K +DL N + + E+ + + H+
Sbjct: 388 VYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVD 447
Query: 69 VADNQISEIEKDALPKGLKHVHLGINKLN--TLNG-ALRDL----DDLEWI--------- 112
+ DN++++++ +L L+ +H G N+L TL+G +LR L + L +
Sbjct: 448 LRDNRLTDLDLSSL-CSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLL 506
Query: 113 -FIN-ANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLD 170
F++ + NL + +AKK++++ ++N L +P + SL+ L N++++L
Sbjct: 507 TFLDLSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNL- 565
Query: 171 ETLQKSRNLMRIGLSFNKIEFLTKDDFTEA-------EKLAELDIAYNELKYLNGSLRSL 223
TL + L + L N + L F++A E+L EL+++ N+LK + ++ +
Sbjct: 566 PTLVEHIPLEVLDLQHNALTRLPDTLFSKALNKLNKLEQLEELNLSGNKLKTIPTTIANC 625
Query: 224 KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
K L L N ++ F EI L ++ +DLS N ++
Sbjct: 626 KRLHTLVAHSNNISIF--PEILQLPQIQFVDLSCNDLT 661
Score = 53.2 bits (122), Expect = 2e-06
Identities = 55/232 (23%), Positives = 103/232 (44%), Gaps = 13/232 (5%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK----DALPK--GLKHVHLGI 93
+ T+DL + ++ E F Q++ +L + N ++E+ D L K LK ++L
Sbjct: 253 ISTVDLSCYSLEEVPEHLFYS-QDITYLNLRHN-FMQLERPGGLDTLYKFSQLKGLNLSH 310
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLM 153
NKL L ++ L + ++ N + +++ +Q + N L +LP +L +
Sbjct: 311 NKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLN-LQTLCLDGNFLTTLPEELGNL 369
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L SL NN + E +K L R+ ++ N +E L + +D+ N L
Sbjct: 370 QQLSSLGISFNNFSQIPEVYEKLTMLDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHL 429
Query: 214 K-YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
K + +L K + +++L N +T+ L + L +L NQ+ LT
Sbjct: 430 KTMVIENLEGNKHITHVDLRDNRLTDLDLSSLCSLEQL---HCGRNQLRELT 478
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 6/245 (2%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
SL N + EL R + L L N+I+ + E+ F+ + +L+ L+++ N+I +
Sbjct: 67 SLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPN 126
Query: 80 DALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
+ L+++ L N+L++L+ L L L+ + + +N+L++I L + ++ +
Sbjct: 127 TTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFL 186
Query: 137 HAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTK 194
+ N L+SL + + L+ L+ N + ++ + +L + L +NKI LT
Sbjct: 187 DLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC 246
Query: 195 DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVI 253
L +LD+ NE+K ++ ++ ++ +L+ L + +N + + + LR L+ +
Sbjct: 247 GMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTV 306
Query: 254 DLSHN 258
LS N
Sbjct: 307 GLSGN 311
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/233 (26%), Positives = 107/233 (45%), Gaps = 6/233 (2%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL- 99
L L N IT+L + F +L L + NQIS +++DA LK + L NK+ L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 100 NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQS 158
N L +L+ + ++ N L S+ EL +K+Q +H N L+++P L SL+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 159 LYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L N ++SL L + L N++ + F L L + +N++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 218 -GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
G + +L L+LT N + L + + L ++ + +N+++ L + N
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 6/236 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F + + L N + + Q L +K L L NKI L F + L
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKS 121
++L ++ NQ+S + + + L+ +HL N L T+ L D LE++ ++ N L+S
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ K++ +H HN+L + + + SL +L+ N I +L ++ + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ L+ N+I+ + F L L + N+L L+ L SL+SL + L+ N
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
Score = 60.5 bits (140), Expect = 2e-08
Identities = 65/263 (24%), Positives = 107/263 (40%), Gaps = 11/263 (4%)
Query: 124 NELPTKAKKMQL-IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ +P K L + HN + L D L L+ N I ++ E Q L
Sbjct: 53 HSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLK 112
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
+ LS NKI +L FT+ L LD+++N+L L+ L L+ L+ L+L N +
Sbjct: 113 ELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI 172
Query: 240 SLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX 298
++ R L +DLS N++ SL L+ ++ EL L+HN +
Sbjct: 173 PVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI----KLRELHLEHNQLTKINFAHFLRL 228
Query: 299 XXXXXXXXX-XXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNN 357
I + ++ N I ++ T +P+L+ L+ +N
Sbjct: 229 SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Query: 358 ITVLD-KDFHGLPSLCSADLSFN 379
+ LD K + L SL + LS N
Sbjct: 289 LNSLDSKILNSLRSLTTVGLSGN 311
Score = 32.7 bits (71), Expect = 3.5
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
+NHIT LE L L HN I+ + +D F GL L LS NKI
Sbjct: 70 HNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 121
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 6/245 (2%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
SL N + EL R + L L N+I+ + E+ F+ + +L+ L+++ N+I +
Sbjct: 67 SLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPN 126
Query: 80 DALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
+ L+++ L N+L++L+ L L L+ + + +N+L++I L + ++ +
Sbjct: 127 TTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFL 186
Query: 137 HAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTK 194
+ N L+SL + + L+ L+ N + ++ + +L + L +NKI LT
Sbjct: 187 DLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC 246
Query: 195 DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVI 253
L +LD+ NE+K ++ ++ ++ +L+ L + +N + + + LR L+ +
Sbjct: 247 GMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTV 306
Query: 254 DLSHN 258
LS N
Sbjct: 307 GLSGN 311
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/233 (26%), Positives = 107/233 (45%), Gaps = 6/233 (2%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL- 99
L L N IT+L + F +L L + NQIS +++DA LK + L NK+ L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 100 NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQS 158
N L +L+ + ++ N L S+ EL +K+Q +H N L+++P L SL+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 159 LYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L N ++SL L + L N++ + F L L + +N++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 218 -GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
G + +L L+LT N + L + + L ++ + +N+++ L + N
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 6/236 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F + + L N + + Q L +K L L NKI L F + L
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKS 121
++L ++ NQ+S + + + L+ +HL N L T+ L D LE++ ++ N L+S
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ K++ +H HN+L + + + SL +L+ N I +L ++ + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ L+ N+I+ + F L L + N+L L+ L SL+SL + L+ N
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
Score = 60.5 bits (140), Expect = 2e-08
Identities = 65/263 (24%), Positives = 107/263 (40%), Gaps = 11/263 (4%)
Query: 124 NELPTKAKKMQL-IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ +P K L + HN + L D L L+ N I ++ E Q L
Sbjct: 53 HSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLK 112
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
+ LS NKI +L FT+ L LD+++N+L L+ L L+ L+ L+L N +
Sbjct: 113 ELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI 172
Query: 240 SLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX 298
++ R L +DLS N++ SL L+ ++ EL L+HN +
Sbjct: 173 PVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI----KLRELHLEHNQLTKINFAHFLRL 228
Query: 299 XXXXXXXXX-XXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNN 357
I + ++ N I ++ T +P+L+ L+ +N
Sbjct: 229 SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Query: 358 ITVLD-KDFHGLPSLCSADLSFN 379
+ LD K + L SL + LS N
Sbjct: 289 LNSLDSKILNSLRSLTTVGLSGN 311
Score = 32.7 bits (71), Expect = 3.5
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
+NHIT LE L L HN I+ + +D F GL L LS NKI
Sbjct: 70 HNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 121
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 6/245 (2%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
SL N + EL R + L L N+I+ + E+ F+ + +L+ L+++ N+I +
Sbjct: 67 SLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPN 126
Query: 80 DALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
+ L+++ L N+L++L+ L L L+ + + +N+L++I L + ++ +
Sbjct: 127 TTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFL 186
Query: 137 HAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTK 194
+ N L+SL + + L+ L+ N + ++ + +L + L +NKI LT
Sbjct: 187 DLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC 246
Query: 195 DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVI 253
L +LD+ NE+K ++ ++ ++ +L+ L + +N + + + LR L+ +
Sbjct: 247 GMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTV 306
Query: 254 DLSHN 258
LS N
Sbjct: 307 GLSGN 311
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/233 (26%), Positives = 107/233 (45%), Gaps = 6/233 (2%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL- 99
L L N IT+L + F +L L + NQIS +++DA LK + L NK+ L
Sbjct: 66 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 125
Query: 100 NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQS 158
N L +L+ + ++ N L S+ EL +K+Q +H N L+++P L SL+
Sbjct: 126 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 159 LYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L N ++SL L + L N++ + F L L + +N++ L
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 245
Query: 218 -GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
G + +L L+LT N + L + + L ++ + +N+++ L + N
Sbjct: 246 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 298
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 6/236 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F + + L N + + Q L +K L L NKI L F + L
Sbjct: 76 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 135
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKS 121
++L ++ NQ+S + + + L+ +HL N L T+ L D LE++ ++ N L+S
Sbjct: 136 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 195
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ K++ +H HN+L + + + SL +L+ N I +L ++ + L
Sbjct: 196 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 255
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ L+ N+I+ + F L L + N+L L+ L SL+SL + L+ N
Sbjct: 256 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 311
Score = 60.5 bits (140), Expect = 2e-08
Identities = 65/263 (24%), Positives = 107/263 (40%), Gaps = 11/263 (4%)
Query: 124 NELPTKAKKMQL-IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ +P K L + HN + L D L L+ N I ++ E Q L
Sbjct: 53 HSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLK 112
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
+ LS NKI +L FT+ L LD+++N+L L+ L L+ L+ L+L N +
Sbjct: 113 ELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI 172
Query: 240 SLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX 298
++ R L +DLS N++ SL L+ ++ EL L+HN +
Sbjct: 173 PVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI----KLRELHLEHNQLTKINFAHFLRL 228
Query: 299 XXXXXXXXX-XXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNN 357
I + ++ N I ++ T +P+L+ L+ +N
Sbjct: 229 SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNK 288
Query: 358 ITVLD-KDFHGLPSLCSADLSFN 379
+ LD K + L SL + LS N
Sbjct: 289 LNSLDSKILNSLRSLTTVGLSGN 311
Score = 32.7 bits (71), Expect = 3.5
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
+NHIT LE L L HN I+ + +D F GL L LS NKI
Sbjct: 70 HNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 121
>AC108017-1|AAY41039.1| 260|Homo sapiens unknown protein.
Length = 260
Score = 69.3 bits (162), Expect = 3e-11
Identities = 55/184 (29%), Positives = 87/184 (47%), Gaps = 6/184 (3%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKL 96
+V + L N I KL + F++ +L+ L + +N+I+ I A L ++L N++
Sbjct: 64 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 123
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD--LKLM 153
L G DL LEW+ I N+L I + L+ +N L LP + M
Sbjct: 124 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 183
Query: 154 PSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
P L L GN+I +L T NL + + NKI L ++ F +KL ELD+ N+
Sbjct: 184 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNK 243
Query: 213 LKYL 216
++ L
Sbjct: 244 IENL 247
Score = 39.5 bits (88), Expect = 0.031
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 7/161 (4%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 94 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 153
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 154 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 212
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQK 175
+ N++ L + + L L N I++L + K
Sbjct: 213 LVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFK 253
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 84 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 143
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 69.3 bits (162), Expect = 3e-11
Identities = 57/245 (23%), Positives = 122/245 (49%), Gaps = 6/245 (2%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEK 79
SL N + EL R + L L N+I+ + E+ F+ + +L+ L+++ N+I +
Sbjct: 80 SLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPN 139
Query: 80 DALPK--GLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKSIENELPTKAKKMQLI 136
+ L+++ L N+L++L+ L L L+ + + +N+L++I L + ++ +
Sbjct: 140 TTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFL 199
Query: 137 HAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTK 194
+ N L+SL + + L+ L+ N + ++ + +L + L +NKI LT
Sbjct: 200 DLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC 259
Query: 195 DDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVI 253
L +LD+ NE+K ++ ++ ++ +L+ L + +N + + + LR L+ +
Sbjct: 260 GMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTV 319
Query: 254 DLSHN 258
LS N
Sbjct: 320 GLSGN 324
Score = 66.9 bits (156), Expect = 2e-10
Identities = 61/233 (26%), Positives = 107/233 (45%), Gaps = 6/233 (2%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTL- 99
L L N IT+L + F +L L + NQIS +++DA LK + L NK+ L
Sbjct: 79 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLP 138
Query: 100 NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQS 158
N L +L+ + ++ N L S+ EL +K+Q +H N L+++P L SL+
Sbjct: 139 NTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 198
Query: 159 LYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L N ++SL L + L N++ + F L L + +N++ L
Sbjct: 199 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLT 258
Query: 218 -GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
G + +L L+LT N + L + + L ++ + +N+++ L + N
Sbjct: 259 CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILN 311
Score = 65.3 bits (152), Expect = 5e-10
Identities = 60/236 (25%), Positives = 109/236 (46%), Gaps = 6/236 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F + + L N + + Q L +K L L NKI L F + L
Sbjct: 89 LERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINL 148
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNLKS 121
++L ++ NQ+S + + + L+ +HL N L T+ L D LE++ ++ N L+S
Sbjct: 149 QNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRS 208
Query: 122 IENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNL 179
+ K++ +H HN+L + + + SL +L+ N I +L ++ + L
Sbjct: 209 LARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTL 268
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHN 234
++ L+ N+I+ + F L L + N+L L+ L SL+SL + L+ N
Sbjct: 269 EKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGN 324
Score = 60.5 bits (140), Expect = 2e-08
Identities = 65/263 (24%), Positives = 107/263 (40%), Gaps = 11/263 (4%)
Query: 124 NELPTKAKKMQL-IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLM 180
+ +P K L + HN + L D L L+ N I ++ E Q L
Sbjct: 66 HSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLK 125
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEF 239
+ LS NKI +L FT+ L LD+++N+L L+ L L+ L+ L+L N +
Sbjct: 126 ELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI 185
Query: 240 SLQEIKGLRRLSVIDLSHNQI-SLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXXXXX 298
++ R L +DLS N++ SL L+ ++ EL L+HN +
Sbjct: 186 PVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLI----KLRELHLEHNQLTKINFAHFLRL 241
Query: 299 XXXXXXXXX-XXIQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNN 357
I + ++ N I ++ T +P+L+ L+ +N
Sbjct: 242 SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNK 301
Query: 358 ITVLD-KDFHGLPSLCSADLSFN 379
+ LD K + L SL + LS N
Sbjct: 302 LNSLDSKILNSLRSLTTVGLSGN 324
Score = 32.7 bits (71), Expect = 3.5
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 331 YNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSADLSFNKI 381
+NHIT LE L L HN I+ + +D F GL L LS NKI
Sbjct: 83 HNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 134
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 68.9 bits (161), Expect = 4e-11
Identities = 67/236 (28%), Positives = 108/236 (45%), Gaps = 8/236 (3%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+L F L + L+ N + LP V Q L ++ LDL N++ ++T E FR ++
Sbjct: 66 MLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRR 125
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
LE L + N+I I+ A L + L N+L L LR L L + ++ N+L +
Sbjct: 126 LERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL-PPLR-LPRLLLLDLSHNSLLA 183
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+E + A ++ + A LQ L L + +L L N ++ + ++ R L
Sbjct: 184 LEPGILDTA-NVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLT 242
Query: 181 RIGLSFN-KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL-KSLRYLNLTHN 234
R+ L+ N +I L +D L ELD++ L+ L G L L LR L N
Sbjct: 243 RLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARN 298
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/172 (26%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL 82
+N + L LP ++ LDL +N+I L F+ + L +L + N++ EI +
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 83 P--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L+ ++LG N++ + GA LD L + + N L+++ P + ++ L+ +
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP---PLRLPRLLLLDLS 177
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIE 190
HN L +L + ++++L G ++ LDE L + RNL + +S N++E
Sbjct: 178 HNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLE 229
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 153 MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+P LQ L N I SL Q NL + L+ N++ +T + F +L L + N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 212 ELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
++++ G+ +L L L L N + +L ++ L RL ++DLSHN + L + +
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNELR--ALPPLR-LPRLLLLDLSHNSLLALEPGILDT 191
Query: 271 VDVE 274
+VE
Sbjct: 192 ANVE 195
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Query: 187 NKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I L F L LD++ N++ L +G + L +L L+LT N + E + + +
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
GLRRL + L N+I + + +D R+LEL+L N +
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLD---RLLELKLQDNEL 160
Score = 32.7 bits (71), Expect = 3.5
Identities = 35/151 (23%), Positives = 65/151 (43%), Gaps = 23/151 (15%)
Query: 133 MQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIE 190
+QL+ + N++ SLPS + + + +L +L N + + +ET + R L R+ L N+I
Sbjct: 78 LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIR 137
Query: 191 FLTKDDFTEAEKLAEL---------------------DIAYNELKYLNGSLRSLKSLRYL 229
+ F ++L EL D+++N L L + ++ L
Sbjct: 138 HIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEAL 197
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L + + LR L +D+S NQ+
Sbjct: 198 RLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 68.9 bits (161), Expect = 4e-11
Identities = 67/236 (28%), Positives = 108/236 (45%), Gaps = 8/236 (3%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+L F L + L+ N + LP V Q L ++ LDL N++ ++T E FR ++
Sbjct: 66 MLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRR 125
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
LE L + N+I I+ A L + L N+L L LR L L + ++ N+L +
Sbjct: 126 LERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL-PPLR-LPRLLLLDLSHNSLLA 183
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+E + A ++ + A LQ L L + +L L N ++ + ++ R L
Sbjct: 184 LEPGILDTA-NVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLT 242
Query: 181 RIGLSFN-KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL-KSLRYLNLTHN 234
R+ L+ N +I L +D L ELD++ L+ L G L L LR L N
Sbjct: 243 RLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARN 298
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/172 (26%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL 82
+N + L LP ++ LDL +N+I L F+ + L +L + N++ EI +
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 83 P--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L+ ++LG N++ + GA LD L + + N L+++ P + ++ L+ +
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP---PLRLPRLLLLDLS 177
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIE 190
HN L +L + ++++L G ++ LDE L + RNL + +S N++E
Sbjct: 178 HNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLE 229
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 153 MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+P LQ L N I SL Q NL + L+ N++ +T + F +L L + N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 212 ELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
++++ G+ +L L L L N + +L ++ L RL ++DLSHN + L + +
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNELR--ALPPLR-LPRLLLLDLSHNSLLALEPGILDT 191
Query: 271 VDVE 274
+VE
Sbjct: 192 ANVE 195
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Query: 187 NKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I L F L LD++ N++ L +G + L +L L+LT N + E + + +
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
GLRRL + L N+I + + +D R+LEL+L N +
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLD---RLLELKLQDNEL 160
Score = 32.7 bits (71), Expect = 3.5
Identities = 35/151 (23%), Positives = 65/151 (43%), Gaps = 23/151 (15%)
Query: 133 MQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIE 190
+QL+ + N++ SLPS + + + +L +L N + + +ET + R L R+ L N+I
Sbjct: 78 LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIR 137
Query: 191 FLTKDDFTEAEKLAEL---------------------DIAYNELKYLNGSLRSLKSLRYL 229
+ F ++L EL D+++N L L + ++ L
Sbjct: 138 HIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEAL 197
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L + + LR L +D+S NQ+
Sbjct: 198 RLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 68.9 bits (161), Expect = 4e-11
Identities = 67/236 (28%), Positives = 108/236 (45%), Gaps = 8/236 (3%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+L F L + L+ N + LP V Q L ++ LDL N++ ++T E FR ++
Sbjct: 66 MLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRR 125
Query: 64 LEHLLVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKS 121
LE L + N+I I+ A L + L N+L L LR L L + ++ N+L +
Sbjct: 126 LERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRAL-PPLR-LPRLLLLDLSHNSLLA 183
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+E + A ++ + A LQ L L + +L L N ++ + ++ R L
Sbjct: 184 LEPGILDTA-NVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLT 242
Query: 181 RIGLSFN-KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL-KSLRYLNLTHN 234
R+ L+ N +I L +D L ELD++ L+ L G L L LR L N
Sbjct: 243 RLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARN 298
Score = 62.1 bits (144), Expect = 5e-09
Identities = 45/172 (26%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Query: 23 DNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDAL 82
+N + L LP ++ LDL +N+I L F+ + L +L + N++ EI +
Sbjct: 61 ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF 120
Query: 83 P--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAA 139
+ L+ ++LG N++ + GA LD L + + N L+++ P + ++ L+ +
Sbjct: 121 RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALP---PLRLPRLLLLDLS 177
Query: 140 HNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIE 190
HN L +L + ++++L G ++ LDE L + RNL + +S N++E
Sbjct: 178 HNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLE 229
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 153 MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+P LQ L N I SL Q NL + L+ N++ +T + F +L L + N
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 134
Query: 212 ELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
++++ G+ +L L L L N + +L ++ L RL ++DLSHN + L + +
Sbjct: 135 RIRHIQPGAFDTLDRLLELKLQDNELR--ALPPLR-LPRLLLLDLSHNSLLALEPGILDT 191
Query: 271 VDVE 274
+VE
Sbjct: 192 ANVE 195
Score = 44.8 bits (101), Expect = 8e-04
Identities = 32/102 (31%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Query: 187 NKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIK 245
N I L F L LD++ N++ L +G + L +L L+LT N + E + + +
Sbjct: 62 NGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFR 121
Query: 246 GLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
GLRRL + L N+I + + +D R+LEL+L N +
Sbjct: 122 GLRRLERLYLGKNRIRHIQPGAFDTLD---RLLELKLQDNEL 160
Score = 32.7 bits (71), Expect = 3.5
Identities = 35/151 (23%), Positives = 65/151 (43%), Gaps = 23/151 (15%)
Query: 133 MQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIE 190
+QL+ + N++ SLPS + + + +L +L N + + +ET + R L R+ L N+I
Sbjct: 78 LQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIR 137
Query: 191 FLTKDDFTEAEKLAEL---------------------DIAYNELKYLNGSLRSLKSLRYL 229
+ F ++L EL D+++N L L + ++ L
Sbjct: 138 HIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEAL 197
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L + + LR L +D+S NQ+
Sbjct: 198 RLAGLGLQQLDEGLFSRLRNLHDLDVSDNQL 228
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>CR457397-1|CAG33678.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 9/263 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L + ++ +P + ++ L NK+T+L E+ ++ L+ L + N +S I
Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 81 AL--PKGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L +HL N+L +N D L +LE + I N + I++ ++ +
Sbjct: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
Query: 138 AAHNELQSLPSD-LKLMPSLQSLYFYGNN-IKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
A L +P + L + +L+S+ FY N IK LQK NL + L+ N I + +
Sbjct: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
Query: 196 DFTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN-YMTEFSLQEIKGLRRLSV 252
DF+ L EL I EL ++ ++ +L LR + T+N ++ L +L
Sbjct: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
Query: 253 IDLSHNQIS-LLTGSLENLVDVE 274
+ L+ N +S L G++E+L +++
Sbjct: 339 LMLNSNALSALYHGTIESLPNLK 361
Score = 46.8 bits (106), Expect = 2e-04
Identities = 38/156 (24%), Positives = 71/156 (45%), Gaps = 3/156 (1%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNI 166
+L + ++ NNL S+ N K ++ ++ N+L LP L + +LQ LY N +
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 167 KSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE-LKYLNGSLRSLK 224
++ NL+R+ L+ N+++ + F L L I N ++ + + + L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
+LR L + +TE + GL L I N++
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+L L +L + Q L NNI ++ + NL + LS N + +T + +
Sbjct: 56 NDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKM 115
Query: 201 EKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+L + + N+L L L L +L+ L + HN ++ S GL L + L+ N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 260 ISLL 263
+ ++
Sbjct: 176 LQMI 179
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + +N + + + L ++++L + +T++ + ++ LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISF 243
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFI-NANNLKSIENE 125
DN++ ++ AL K LK + L N +N + G ++ L+ + I N L SI++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ I A +N S P+ +P L+SL N + +L T++ NL I
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 183 GLSFNKI 189
+ N I
Sbjct: 364 SIHSNPI 370
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ ++ L+ ++ S DN L ++P LQ + ++K LDL +N I ++ DF ++ L
Sbjct: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
Query: 65 EHLLVADN----QISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ L + + I + D LP K +L+ ++ A L LE + +N+N L
Sbjct: 287 KELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNAL 346
Query: 120 KSI 122
++
Sbjct: 347 SAL 349
Score = 31.9 bits (69), Expect = 6.2
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N +T L E + L +L+EL +HN + T+ F GL +L L+ N++ +N S
Sbjct: 126 NKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN----S 181
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
K + +P++ + + +NP++
Sbjct: 182 K---WFDALPNLEILMIGENPII 201
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 42 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 99
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 100 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 157
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 158 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 198
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 53 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 111
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 112 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 168
>BC035133-1|AAH35133.1| 708|Homo sapiens leucine rich repeat
neuronal 3 protein.
Length = 708
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 9/263 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L + ++ +P + ++ L NK+T+L E+ ++ L+ L + N +S I
Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 81 AL--PKGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L +HL N+L +N D L +LE + I N + I++ ++ +
Sbjct: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
Query: 138 AAHNELQSLPSD-LKLMPSLQSLYFYGNN-IKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
A L +P + L + +L+S+ FY N IK LQK NL + L+ N I + +
Sbjct: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
Query: 196 DFTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN-YMTEFSLQEIKGLRRLSV 252
DF+ L EL I EL ++ ++ +L LR + T+N ++ L +L
Sbjct: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
Query: 253 IDLSHNQIS-LLTGSLENLVDVE 274
+ L+ N +S L G++E+L +++
Sbjct: 339 LMLNSNALSALYHGTIESLPNLK 361
Score = 42.3 bits (95), Expect = 0.004
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+L L +L + Q L NNI ++ + NL + LS N + +T + +
Sbjct: 56 NDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTSLDLSQNNLSSVTNINVKKM 115
Query: 201 EKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+L + + N+L L L L +L+ L + HN ++ S GL L + L+ N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 260 ISLL 263
+ ++
Sbjct: 176 LQMI 179
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + +N + + + L ++++L + +T++ + ++ LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISF 243
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFI-NANNLKSIENE 125
DN++ ++ AL K LK + L N +N + G ++ L+ + I N L SI++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ I A +N S P+ +P L+SL N + +L T++ NL I
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 183 GLSFNKI 189
+ N I
Sbjct: 364 SIHSNPI 370
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ ++ L+ ++ S DN L ++P LQ + ++K LDL +N I ++ DF ++ L
Sbjct: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
Query: 65 EHLLVADN----QISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ L + + I + D LP K +L+ ++ A L LE + +N+N L
Sbjct: 287 KELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNAL 346
Query: 120 KSI 122
++
Sbjct: 347 SAL 349
Score = 31.9 bits (69), Expect = 6.2
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N +T L E + L +L+EL +HN + T+ F GL +L L+ N++ +N S
Sbjct: 126 NKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN----S 181
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
K + +P++ + + +NP++
Sbjct: 182 K---WFDALPNLEILMIGENPII 201
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 68.5 bits (160), Expect = 6e-11
Identities = 55/237 (23%), Positives = 116/237 (48%), Gaps = 6/237 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGI 93
L+ L H+K L + ++ +TK+ L L++ ++ + ++L K + L +
Sbjct: 584 LRELRHLKILHV-KSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELEL 642
Query: 94 N--KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
+L + A+ L +L+ + + +NN+++IE + + K++ + HN++ ++P +
Sbjct: 643 QNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSI 702
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ +L+SLYF N ++SL + + L + +S+N I + + + L L I
Sbjct: 703 THVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMI-PIEIGLLQNLQHLHITG 761
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N++ L L LR LNL N +T +++ L +L+ ++L N + L L
Sbjct: 762 NKVDILPKQLFKCIKLRTLNLGQNCITSLP-EKVGQLSQLTQLELKGNCLDRLPAQL 817
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/141 (21%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+++ +N++ L S L+ + L+ L+ N K + +L ++ + + + L +
Sbjct: 571 LNSENNKMIGLES-LRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLN 629
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL-THNYMTEFSLQEIKGLRRLSVID 254
+ +AEL++ EL+ + ++ SL +L+ L+L ++N T + + L+RL+ +
Sbjct: 630 SLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLK 689
Query: 255 LSHNQISLLTGSLENLVDVET 275
L HN+I + S+ ++ ++E+
Sbjct: 690 LWHNKIVTIPPSITHVKNLES 710
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 68.5 bits (160), Expect = 6e-11
Identities = 55/237 (23%), Positives = 116/237 (48%), Gaps = 6/237 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGI 93
L+ L H+K L + ++ +TK+ L L++ ++ + ++L K + L +
Sbjct: 227 LRELRHLKILHV-KSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELEL 285
Query: 94 N--KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
+L + A+ L +L+ + + +NN+++IE + + K++ + HN++ ++P +
Sbjct: 286 QNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSI 345
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ +L+SLYF N ++SL + + L + +S+N I + + + L L I
Sbjct: 346 THVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMI-PIEIGLLQNLQHLHITG 404
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N++ L L LR LNL N +T +++ L +L+ ++L N + L L
Sbjct: 405 NKVDILPKQLFKCIKLRTLNLGQNCITSLP-EKVGQLSQLTQLELKGNCLDRLPAQL 460
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/141 (21%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+++ +N++ L S L+ + L+ L+ N K + +L ++ + + + L +
Sbjct: 214 LNSENNKMIGLES-LRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLN 272
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL-THNYMTEFSLQEIKGLRRLSVID 254
+ +AEL++ EL+ + ++ SL +L+ L+L ++N T + + L+RL+ +
Sbjct: 273 SLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLK 332
Query: 255 LSHNQISLLTGSLENLVDVET 275
L HN+I + S+ ++ ++E+
Sbjct: 333 LWHNKIVTIPPSITHVKNLES 353
>AY358280-1|AAQ88647.1| 708|Homo sapiens LRRN3 protein.
Length = 708
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 9/263 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L + ++ +P + ++ L NK+T+L E+ ++ L+ L + N +S I
Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 81 AL--PKGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L +HL N+L +N D L +LE + I N + I++ ++ +
Sbjct: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
Query: 138 AAHNELQSLPSD-LKLMPSLQSLYFYGNN-IKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
A L +P + L + +L+S+ FY N IK LQK NL + L+ N I + +
Sbjct: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
Query: 196 DFTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN-YMTEFSLQEIKGLRRLSV 252
DF+ L EL I EL ++ ++ +L LR + T+N ++ L +L
Sbjct: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
Query: 253 IDLSHNQIS-LLTGSLENLVDVE 274
+ L+ N +S L G++E+L +++
Sbjct: 339 LMLNSNALSALYHGTIESLPNLK 361
Score = 46.8 bits (106), Expect = 2e-04
Identities = 38/156 (24%), Positives = 71/156 (45%), Gaps = 3/156 (1%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNI 166
+L + ++ NNL S+ N K ++ ++ N+L LP L + +LQ LY N +
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 167 KSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE-LKYLNGSLRSLK 224
++ NL+R+ L+ N+++ + F L L I N ++ + + + L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
+LR L + +TE + GL L I N++
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+L L +L + Q L NNI ++ + NL + LS N + +T + +
Sbjct: 56 NDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKM 115
Query: 201 EKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+L + + N+L L L L +L+ L + HN ++ S GL L + L+ N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 260 ISLL 263
+ ++
Sbjct: 176 LQMI 179
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + +N + + + L ++++L + +T++ + ++ LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISF 243
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFI-NANNLKSIENE 125
DN++ ++ AL K LK + L N +N + G ++ L+ + I N L SI++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ I A +N S P+ +P L+SL N + +L T++ NL I
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 183 GLSFNKI 189
+ N I
Sbjct: 364 SIHSNPI 370
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ ++ L+ ++ S DN L ++P LQ + ++K LDL +N I ++ DF ++ L
Sbjct: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
Query: 65 EHLLVADN----QISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ L + + I + D LP K +L+ ++ A L LE + +N+N L
Sbjct: 287 KELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNAL 346
Query: 120 KSI 122
++
Sbjct: 347 SAL 349
Score = 31.9 bits (69), Expect = 6.2
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N +T L E + L +L+EL +HN + T+ F GL +L L+ N++ +N S
Sbjct: 126 NKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN----S 181
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
K + +P++ + + +NP++
Sbjct: 182 K---WFDALPNLEILMIGENPII 201
>AY358114-1|AAQ88481.1| 606|Homo sapiens Tango hlg protein.
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 73/270 (27%), Positives = 117/270 (43%), Gaps = 20/270 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
++ F L + L N L +P V L ++ LD+ NKI L + F+D+ L
Sbjct: 96 VEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNL 155
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE- 123
+ L V DN + I A L L + K N L L + + +LK +
Sbjct: 156 KSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLI--SLHLKHLNI 213
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDET----------- 172
N +P A K +L H H E+ P L +MP+ SL YG N+ SL T
Sbjct: 214 NNMPVYAFK-RLFHLKHLEIDYWPL-LDMMPA-NSL--YGLNLTSLSVTNTNLSTVPFLA 268
Query: 173 LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNL 231
+ L + LS+N I + F++ +L EL I +L+ + S + L+ LR LN+
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 328
Query: 232 THNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
+ N + R L V+ +++N ++
Sbjct: 329 SQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 47.6 bits (108), Expect = 1e-04
Identities = 57/242 (23%), Positives = 109/242 (45%), Gaps = 9/242 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNT 98
K LDL +N++ + E+F LE + ++DN I+ +E A L+ + L N+L
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 99 LN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ G L +L + I+ N + + + + ++ + N+L + + SL
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ L N+ ++ E L R+L+ + L I + F L L+I Y L
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 216 L--NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVD 272
+ SL L +L L++T+ ++ K L L+ ++LS+N IS + G +L+
Sbjct: 240 MMPANSLYGL-NLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 273 VE 274
++
Sbjct: 299 LQ 300
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 68.5 bits (160), Expect = 6e-11
Identities = 55/237 (23%), Positives = 116/237 (48%), Gaps = 6/237 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGI 93
L+ L H+K L + ++ +TK+ L L++ ++ + ++L K + L +
Sbjct: 584 LRELRHLKILHV-KSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELEL 642
Query: 94 N--KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
+L + A+ L +L+ + + +NN+++IE + + K++ + HN++ ++P +
Sbjct: 643 QNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSI 702
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ +L+SLYF N ++SL + + L + +S+N I + + + L L I
Sbjct: 703 THVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMI-PIEIGLLQNLQHLHITG 761
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N++ L L LR LNL N +T +++ L +L+ ++L N + L L
Sbjct: 762 NKVDILPKQLFKCIKLRTLNLGQNCITSLP-EKVGQLSQLTQLELKGNCLDRLPAQL 817
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/141 (21%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+++ +N++ L S L+ + L+ L+ N K + +L ++ + + + L +
Sbjct: 571 LNSENNKMIGLES-LRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLN 629
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL-THNYMTEFSLQEIKGLRRLSVID 254
+ +AEL++ EL+ + ++ SL +L+ L+L ++N T + + L+RL+ +
Sbjct: 630 SLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLK 689
Query: 255 LSHNQISLLTGSLENLVDVET 275
L HN+I + S+ ++ ++E+
Sbjct: 690 LWHNKIVTIPPSITHVKNLES 710
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 68.5 bits (160), Expect = 6e-11
Identities = 49/161 (30%), Positives = 84/161 (52%), Gaps = 9/161 (5%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGIN 94
L H+ L L NK+T + + +++ LE L +NQI E+ + +L K LKH++LG+N
Sbjct: 39 LSHITQLVLSHNKLT-MVPPNIAELKNLEVLNFFNNQIEELPTQISSLQK-LKHLNLGMN 96
Query: 95 KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK---AKKMQLIHAAHNELQSLPSDLK 151
+LNTL L LE + + NNL EN LP ++ ++ + N+ + LP D+
Sbjct: 97 RLNTLPRGFGSLPALEVLDLTYNNLS--ENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
+ LQ L N++ SL + + + L + + N++ L
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNRLTVL 195
Score = 40.3 bits (90), Expect = 0.018
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 4/119 (3%)
Query: 164 NNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSL 223
N + + + + +NL + N+IE L + +KL L++ N L L SL
Sbjct: 50 NKLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSL 108
Query: 224 KSLRYLNLTHNYMTEFSLQ-EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELR 281
+L L+LT+N ++E SL L L + LS N +L + L ++ +L LR
Sbjct: 109 PALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQ--ILSLR 165
>AL353746-1|CAC22713.1| 606|Homo sapiens leucine rich repeat
neuronal 6C protein.
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 73/270 (27%), Positives = 117/270 (43%), Gaps = 20/270 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
++ F L + L N L +P V L ++ LD+ NKI L + F+D+ L
Sbjct: 96 VEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNL 155
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE- 123
+ L V DN + I A L L + K N L L + + +LK +
Sbjct: 156 KSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLI--SLHLKHLNI 213
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDET----------- 172
N +P A K +L H H E+ P L +MP+ SL YG N+ SL T
Sbjct: 214 NNMPVYAFK-RLFHLKHLEIDYWPL-LDMMPA-NSL--YGLNLTSLSVTNTNLSTVPFLA 268
Query: 173 LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNL 231
+ L + LS+N I + F++ +L EL I +L+ + S + L+ LR LN+
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 328
Query: 232 THNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
+ N + R L V+ +++N ++
Sbjct: 329 SQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 47.6 bits (108), Expect = 1e-04
Identities = 57/242 (23%), Positives = 109/242 (45%), Gaps = 9/242 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNT 98
K LDL +N++ + E+F LE + ++DN I+ +E A L+ + L N+L
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 99 LN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ G L +L + I+ N + + + + ++ + N+L + + SL
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ L N+ ++ E L R+L+ + L I + F L L+I Y L
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 216 L--NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVD 272
+ SL L +L L++T+ ++ K L L+ ++LS+N IS + G +L+
Sbjct: 240 MMPANSLYGL-NLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 273 VE 274
++
Sbjct: 299 LQ 300
>AK056372-1|BAB71167.1| 606|Homo sapiens protein ( Homo sapiens
cDNA FLJ31810 fis, clone NT2RI2009289, weakly similar to
CARBOXYPEPTIDASE N 83 KD CHAIN. ).
Length = 606
Score = 68.5 bits (160), Expect = 6e-11
Identities = 73/270 (27%), Positives = 117/270 (43%), Gaps = 20/270 (7%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
++ F L + L N L +P V L ++ LD+ NKI L + F+D+ L
Sbjct: 96 VEPGAFNNLFNLRSLRLKGNRLKLVPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNL 155
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIE- 123
+ L V DN + I A L L + K N L L + + +LK +
Sbjct: 156 KSLEVGDNDLVYISHRAFSGLLSLEQLTLEKCNLTAVPTEALSHLRSLI--SLHLKHLNI 213
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDET----------- 172
N +P A K +L H H E+ P L +MP+ SL YG N+ SL T
Sbjct: 214 NNMPVYAFK-RLFHLKHLEIDYWPL-LDMMPA-NSL--YGLNLTSLSVTNTNLSTVPFLA 268
Query: 173 LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNL 231
+ L + LS+N I + F++ +L EL I +L+ + S + L+ LR LN+
Sbjct: 269 FKHLVYLTHLNLSYNPISTIEAGMFSDLIRLQELHIVGAQLRTIEPHSFQGLRFLRVLNV 328
Query: 232 THNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
+ N + R L V+ +++N ++
Sbjct: 329 SQNLLETLEENVFSSPRALEVLSINNNPLA 358
Score = 47.6 bits (108), Expect = 1e-04
Identities = 57/242 (23%), Positives = 109/242 (45%), Gaps = 9/242 (3%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNT 98
K LDL +N++ + E+F LE + ++DN I+ +E A L+ + L N+L
Sbjct: 60 KILDLSKNRLKSVNPEEFISYPLLEEIDLSDNIIANVEPGAFNNLFNLRSLRLKGNRLKL 119
Query: 99 LN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSL 156
+ G L +L + I+ N + + + + ++ + N+L + + SL
Sbjct: 120 VPLGVFTGLSNLTKLDISENKIVILLDYMFQDLHNLKSLEVGDNDLVYISHRAFSGLLSL 179
Query: 157 QSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ L N+ ++ E L R+L+ + L I + F L L+I Y L
Sbjct: 180 EQLTLEKCNLTAVPTEALSHLRSLISLHLKHLNINNMPVYAFKRLFHLKHLEIDYWPLLD 239
Query: 216 L--NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVD 272
+ SL L +L L++T+ ++ K L L+ ++LS+N IS + G +L+
Sbjct: 240 MMPANSLYGL-NLTSLSVTNTNLSTVPFLAFKHLVYLTHLNLSYNPISTIEAGMFSDLIR 298
Query: 273 VE 274
++
Sbjct: 299 LQ 300
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ10470 fis, clone NT2RP2000032, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 68.5 bits (160), Expect = 6e-11
Identities = 55/237 (23%), Positives = 116/237 (48%), Gaps = 6/237 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGI 93
L+ L H+K L + ++ +TK+ L L++ ++ + ++L K + L +
Sbjct: 408 LRELRHLKILHV-KSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELEL 466
Query: 94 N--KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
+L + A+ L +L+ + + +NN+++IE + + K++ + HN++ ++P +
Sbjct: 467 QNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSI 526
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ +L+SLYF N ++SL + + L + +S+N I + + + L L I
Sbjct: 527 THVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMI-PIEIGLLQNLQHLHITG 585
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N++ L L LR LNL N +T +++ L +L+ ++L N + L L
Sbjct: 586 NKVDILPKQLFKCIKLRTLNLGQNCITSLP-EKVGQLSQLTQLELKGNCLDRLPAQL 641
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/141 (21%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+++ +N++ L S L+ + L+ L+ N K + +L ++ + + + L +
Sbjct: 395 LNSENNKMIGLES-LRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLN 453
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL-THNYMTEFSLQEIKGLRRLSVID 254
+ +AEL++ EL+ + ++ SL +L+ L+L ++N T + + L+RL+ +
Sbjct: 454 SLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLK 513
Query: 255 LSHNQISLLTGSLENLVDVET 275
L HN+I + S+ ++ ++E+
Sbjct: 514 LWHNKIVTIPPSITHVKNLES 534
>AF134481-1|AAP97258.1| 708|Homo sapiens leucine-rich repeat
protein protein.
Length = 708
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 9/263 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L + ++ +P + ++ L NK+T+L E+ ++ L+ L + N +S I
Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 81 AL--PKGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L +HL N+L +N D L +LE + I N + I++ ++ +
Sbjct: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
Query: 138 AAHNELQSLPSD-LKLMPSLQSLYFYGNN-IKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
A L +P + L + +L+S+ FY N IK LQK NL + L+ N I + +
Sbjct: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
Query: 196 DFTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN-YMTEFSLQEIKGLRRLSV 252
DF+ L EL I EL ++ ++ +L LR + T+N ++ L +L
Sbjct: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
Query: 253 IDLSHNQIS-LLTGSLENLVDVE 274
+ L+ N +S L G++E+L +++
Sbjct: 339 LMLNSNALSALYHGTIESLPNLK 361
Score = 46.8 bits (106), Expect = 2e-04
Identities = 38/156 (24%), Positives = 71/156 (45%), Gaps = 3/156 (1%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNI 166
+L + ++ NNL S+ N K ++ ++ N+L LP L + +LQ LY N +
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 167 KSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE-LKYLNGSLRSLK 224
++ NL+R+ L+ N+++ + F L L I N ++ + + + L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
+LR L + +TE + GL L I N++
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+L L +L + Q L NNI ++ + NL + LS N + +T + +
Sbjct: 56 NDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKM 115
Query: 201 EKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+L + + N+L L L L +L+ L + HN ++ S GL L + L+ N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 260 ISLL 263
+ ++
Sbjct: 176 LQMI 179
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + +N + + + L ++++L + +T++ + ++ LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISF 243
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFI-NANNLKSIENE 125
DN++ ++ AL K LK + L N +N + G ++ L+ + I N L SI++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ I A +N S P+ +P L+SL N + +L T++ NL I
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 183 GLSFNKI 189
+ N I
Sbjct: 364 SIHSNPI 370
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ ++ L+ ++ S DN L ++P LQ + ++K LDL +N I ++ DF ++ L
Sbjct: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
Query: 65 EHLLVADN----QISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ L + + I + D LP K +L+ ++ A L LE + +N+N L
Sbjct: 287 KELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNAL 346
Query: 120 KSI 122
++
Sbjct: 347 SAL 349
Score = 31.9 bits (69), Expect = 6.2
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N +T L E + L +L+EL +HN + T+ F GL +L L+ N++ +N S
Sbjct: 126 NKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN----S 181
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
K + +P++ + + +NP++
Sbjct: 182 K---WFDALPNLEILMIGENPII 201
>AB060967-1|BAB47184.1| 708|Homo sapiens neuronal leucine-rich
repeat protein-3 protein.
Length = 708
Score = 68.5 bits (160), Expect = 6e-11
Identities = 70/263 (26%), Positives = 128/263 (48%), Gaps = 9/263 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N+L + ++ +P + ++ L NK+T+L E+ ++ L+ L + N +S I
Sbjct: 99 LSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPG 158
Query: 81 AL--PKGLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
A L +HL N+L +N D L +LE + I N + I++ ++ +
Sbjct: 159 AFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLV 218
Query: 138 AAHNELQSLPSD-LKLMPSLQSLYFYGNN-IKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
A L +P + L + +L+S+ FY N IK LQK NL + L+ N I + +
Sbjct: 219 IAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRG 278
Query: 196 DFTEAEKLAELDI-AYNELKYLNG-SLRSLKSLRYLNLTHN-YMTEFSLQEIKGLRRLSV 252
DF+ L EL I EL ++ ++ +L LR + T+N ++ L +L
Sbjct: 279 DFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLES 338
Query: 253 IDLSHNQIS-LLTGSLENLVDVE 274
+ L+ N +S L G++E+L +++
Sbjct: 339 LMLNSNALSALYHGTIESLPNLK 361
Score = 46.8 bits (106), Expect = 2e-04
Identities = 38/156 (24%), Positives = 71/156 (45%), Gaps = 3/156 (1%)
Query: 108 DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNI 166
+L + ++ NNL S+ N K ++ ++ N+L LP L + +LQ LY N +
Sbjct: 93 NLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLL 152
Query: 167 KSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE-LKYLNGSLRSLK 224
++ NL+R+ L+ N+++ + F L L I N ++ + + + L
Sbjct: 153 STISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLI 212
Query: 225 SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
+LR L + +TE + GL L I N++
Sbjct: 213 NLRSLVIAGINLTEIPDNALVGLENLESISFYDNRL 248
Score = 41.9 bits (94), Expect = 0.006
Identities = 31/124 (25%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+L L +L + Q L NNI ++ + NL + LS N + +T + +
Sbjct: 56 NDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKM 115
Query: 201 EKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
+L + + N+L L L L +L+ L + HN ++ S GL L + L+ N+
Sbjct: 116 PQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNR 175
Query: 260 ISLL 263
+ ++
Sbjct: 176 LQMI 179
Score = 41.1 bits (92), Expect = 0.010
Identities = 42/187 (22%), Positives = 85/187 (45%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + +N + + + L ++++L + +T++ + ++ LE +
Sbjct: 184 FDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISF 243
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFI-NANNLKSIENE 125
DN++ ++ AL K LK + L N +N + G ++ L+ + I N L SI++
Sbjct: 244 YDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSL 303
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ I A +N S P+ +P L+SL N + +L T++ NL I
Sbjct: 304 AVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEI 363
Query: 183 GLSFNKI 189
+ N I
Sbjct: 364 SIHSNPI 370
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 5/123 (4%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
+ ++ L+ ++ S DN L ++P LQ + ++K LDL +N I ++ DF ++ L
Sbjct: 227 IPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHL 286
Query: 65 EHLLVADN----QISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNL 119
+ L + + I + D LP K +L+ ++ A L LE + +N+N L
Sbjct: 287 KELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNAL 346
Query: 120 KSI 122
++
Sbjct: 347 SAL 349
Score = 31.9 bits (69), Expect = 6.2
Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 8/83 (9%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVNYDLVS 390
N +T L E + L +L+EL +HN + T+ F GL +L L+ N++ +N S
Sbjct: 126 NKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMIN----S 181
Query: 391 KSRCTINGVPSILKIYLQDNPVL 413
K + +P++ + + +NP++
Sbjct: 182 K---WFDALPNLEILMIGENPII 201
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 68.1 bits (159), Expect = 8e-11
Identities = 55/237 (23%), Positives = 116/237 (48%), Gaps = 6/237 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGI 93
L+ L H+K L + ++ +TK+ L L++ ++ + ++L K + L +
Sbjct: 397 LRELRHLKILHV-KSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELEL 455
Query: 94 N--KLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
+L + A+ L +L+ + + +NN+++IE + + K++ + HN++ ++P +
Sbjct: 456 QNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSI 515
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ +L+SLYF N ++SL + + L + +S+N I + + + L L I
Sbjct: 516 THVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMI-PIEIGLLQDLQHLHITG 574
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N++ L L LR LNL N +T +++ L +L+ ++L N + L L
Sbjct: 575 NKVDILPKQLFKCIKLRTLNLGQNCITSLP-EKVGQLSQLTQLELKGNCLDRLPAQL 630
Score = 39.9 bits (89), Expect = 0.023
Identities = 31/141 (21%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Query: 136 IHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD 195
+++ +N++ L S L+ + L+ L+ N K + +L ++ + + + L +
Sbjct: 384 LNSENNKMIGLES-LRELRHLKILHVKSNLTKVPSNITDVAPHLTKLVIHNDGTKLLVLN 442
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNL-THNYMTEFSLQEIKGLRRLSVID 254
+ +AEL++ EL+ + ++ SL +L+ L+L ++N T + + L+RL+ +
Sbjct: 443 SLKKMMNVAELELQNCELERIPHAIFSLSNLQELDLKSNNIRTIEEIISFQHLKRLTCLK 502
Query: 255 LSHNQISLLTGSLENLVDVET 275
L HN+I + S+ ++ ++E+
Sbjct: 503 LWHNKIVTIPPSITHVKNLES 523
>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 67.7 bits (158), Expect = 1e-10
Identities = 75/281 (26%), Positives = 137/281 (48%), Gaps = 20/281 (7%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L+ ++ L N+L P+ + + L + LDL NK T + + + +L V+ N
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLK-MSCIANLDVSRN 1068
Query: 73 QIS-EIEKDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPT 128
I + D K LK +L N+L+ + L D ++ LE + + N + I + P
Sbjct: 1069 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICS--PL 1126
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ K++++++ + N + SL + L+ P ++S N + ++ L S +++ LS N
Sbjct: 1127 RLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAM-PFLPPSMTILK--LSQN 1183
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--RSLKSLRYLNLTHNYMTEFSLQEIK 245
K + + L LD++ N+++YL G +SL +LR L +HN ++ L E
Sbjct: 1184 KFSCI-PEAILNLPHLRSLDMSSNDIQYLPGPAHWKSL-NLRELLFSHNQISILDLSEKA 1241
Query: 246 GL-RRLSVIDLSHNQISLL---TGSLENLVDVETRV-LELR 281
L R+ + LSHN++ + G LENL ++ LELR
Sbjct: 1242 YLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELR 1282
Score = 49.6 bits (113), Expect = 3e-05
Identities = 58/259 (22%), Positives = 117/259 (45%), Gaps = 17/259 (6%)
Query: 36 HLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGIN 94
HL H++ L+L +N +T ++ ++ L HL + N+ + L + ++ + N
Sbjct: 1009 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 1068
Query: 95 KLN---TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
+ L+ ++ L+ ++ N L + L +K++ + N++ + S L+
Sbjct: 1069 DIGPSVVLDPTVK-CPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPLR 1127
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L L+ L N+I SL E ++ ++ ++ FL F + L ++ N
Sbjct: 1128 L-KELKILNLSKNHISSLSENFLEA--CPKVESFSARMNFLAAMPFL-PPSMTILKLSQN 1183
Query: 212 ELKYLNGSLRSLKSLRYLNLTHN---YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLE 268
+ + ++ +L LR L+++ N Y+ + + LR L SHNQIS+L L
Sbjct: 1184 KFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELL---FSHNQISIL--DLS 1238
Query: 269 NLVDVETRVLELRLDHNHI 287
+ +RV +L L HN +
Sbjct: 1239 EKAYLWSRVEKLHLSHNKL 1257
Score = 44.8 bits (101), Expect = 8e-04
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--- 77
L+ N +P +L +LPH+++LD+ N I L L LL + NQIS +
Sbjct: 1180 LSQNKFSCIPEAIL-NLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLS 1238
Query: 78 EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINAN-NLKSIENELPTKAK 131
EK L ++ +HL NKL + + L++L + ++ N L+S NE+ +K
Sbjct: 1239 EKAYLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSK 1293
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 67.7 bits (158), Expect = 1e-10
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 5/174 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N L L L+ +P ++ LDL RN +T L F+ L+ L++ +NQ+ +E
Sbjct: 99 LSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVS 158
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
L K L H+ L N+L L G L + L + + N L+++ +L +++ +H
Sbjct: 159 WLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLH 218
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKI 189
N+LQ L DL L P L+ L+ GN + + Q R L + LS N +
Sbjct: 219 LEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSL 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 50/180 (27%), Positives = 87/180 (48%), Gaps = 4/180 (2%)
Query: 86 LKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ +HL N L +L+ LR + L + + N L + + L + + + N+L+
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLE 153
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEK 202
L S L + +L L GN ++ L L + L+R + L N++E L D +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 203 LAELDIAYNELKYLNGSLRSLK-SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N+L+ L L + LRYL L N + + +GLR+L ++DLS+N ++
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L +F +D L +N L L L L + LDL N++ KL + L
Sbjct: 131 LPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLL 190
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L + +NQ+ + D L P L+ +HL NKL L L DL ++F+N N L
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL 150
+ +++ ++ ++N L S+P L
Sbjct: 251 VAAGAFQGLRQLDMLDLSNNSLASVPEGL 279
Score = 50.0 bits (114), Expect = 2e-05
Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ S L + + L+ N L +LP +L + ++TLDL N++ L + R +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 64 LEHLLVADNQISEIEKD-ALPK-GLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLK 120
LE L + N++ + KD LP+ L+++ L NKL GA + L L+ + ++ N+L
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 121 SIENEL 126
S+ L
Sbjct: 274 SVPEGL 279
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 3/128 (2%)
Query: 143 LQSLPSDLKLMPS-LQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
L LP++L S LQ L+ N ++SL E L+ L + L+ N + L F +
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 201 EKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L + N+L+ L S L LK+L +L+L+ N + + + L +DL NQ
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 260 ISLLTGSL 267
+ L L
Sbjct: 200 LETLPPDL 207
Score = 34.7 bits (76), Expect = 0.87
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTE 238
+ + + F + L + A KL EL ++ N L+ L+ LR + LR L+LT N +T
Sbjct: 71 VHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTG 130
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ L + L NQ+ +L
Sbjct: 131 LPSGLFQASATLDTLVLKENQLEVL 155
>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 67.7 bits (158), Expect = 1e-10
Identities = 75/281 (26%), Positives = 137/281 (48%), Gaps = 20/281 (7%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L+ ++ L N+L P+ + + L + LDL NK T + + + +L V+ N
Sbjct: 1010 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLK-MSCIANLDVSRN 1068
Query: 73 QIS-EIEKDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPT 128
I + D K LK +L N+L+ + L D ++ LE + + N + I + P
Sbjct: 1069 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICS--PL 1126
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ K++++++ + N + SL + L+ P ++S N + ++ L S +++ LS N
Sbjct: 1127 RLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAM-PFLPPSMTILK--LSQN 1183
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--RSLKSLRYLNLTHNYMTEFSLQEIK 245
K + + L LD++ N+++YL G +SL +LR L +HN ++ L E
Sbjct: 1184 KFSCI-PEAILNLPHLRSLDMSSNDIQYLPGPAHWKSL-NLRELLFSHNQISILDLSEKA 1241
Query: 246 GL-RRLSVIDLSHNQISLL---TGSLENLVDVETRV-LELR 281
L R+ + LSHN++ + G LENL ++ LELR
Sbjct: 1242 YLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELR 1282
Score = 49.6 bits (113), Expect = 3e-05
Identities = 58/259 (22%), Positives = 117/259 (45%), Gaps = 17/259 (6%)
Query: 36 HLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGIN 94
HL H++ L+L +N +T ++ ++ L HL + N+ + L + ++ + N
Sbjct: 1009 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 1068
Query: 95 KLN---TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
+ L+ ++ L+ ++ N L + L +K++ + N++ + S L+
Sbjct: 1069 DIGPSVVLDPTVK-CPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPLR 1127
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L L+ L N+I SL E ++ ++ ++ FL F + L ++ N
Sbjct: 1128 L-KELKILNLSKNHISSLSENFLEA--CPKVESFSARMNFLAAMPFL-PPSMTILKLSQN 1183
Query: 212 ELKYLNGSLRSLKSLRYLNLTHN---YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLE 268
+ + ++ +L LR L+++ N Y+ + + LR L SHNQIS+L L
Sbjct: 1184 KFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELL---FSHNQISIL--DLS 1238
Query: 269 NLVDVETRVLELRLDHNHI 287
+ +RV +L L HN +
Sbjct: 1239 EKAYLWSRVEKLHLSHNKL 1257
Score = 44.8 bits (101), Expect = 8e-04
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--- 77
L+ N +P +L +LPH+++LD+ N I L L LL + NQIS +
Sbjct: 1180 LSQNKFSCIPEAIL-NLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLS 1238
Query: 78 EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINAN-NLKSIENELPTKAK 131
EK L ++ +HL NKL + + L++L + ++ N L+S NE+ +K
Sbjct: 1239 EKAYLWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSK 1293
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 67.7 bits (158), Expect = 1e-10
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 5/174 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N L L L+ +P ++ LDL RN +T L F+ L+ L++ +NQ+ +E
Sbjct: 99 LSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLEVLEVS 158
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
L K L H+ L N+L L G L + L + + N L+++ +L +++ +H
Sbjct: 159 WLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLH 218
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKI 189
N+LQ L DL L P L+ L+ GN + + Q R L + LS N +
Sbjct: 219 LEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSL 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 50/180 (27%), Positives = 87/180 (48%), Gaps = 4/180 (2%)
Query: 86 LKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ +HL N L +L+ LR + L + + N L + + L + + + N+L+
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQASATLDTLVLKENQLE 153
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEK 202
L S L + +L L GN ++ L L + L+R + L N++E L D +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 203 LAELDIAYNELKYLNGSLRSLK-SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N+L+ L L + LRYL L N + + +GLR+L ++DLS+N ++
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Score = 52.8 bits (121), Expect = 3e-06
Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L +F +D L +N L L L L + LDL N++ KL + L
Sbjct: 131 LPSGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLL 190
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L + +NQ+ + D L P L+ +HL NKL L L DL ++F+N N L
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL 150
+ +++ ++ ++N L S+P L
Sbjct: 251 VAAGAFQGLRQLDMLDLSNNSLASVPEGL 279
Score = 50.0 bits (114), Expect = 2e-05
Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ S L + + L+ N L +LP +L + ++TLDL N++ L + R +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 64 LEHLLVADNQISEIEKD-ALPK-GLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLK 120
LE L + N++ + KD LP+ L+++ L NKL GA + L L+ + ++ N+L
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 121 SIENEL 126
S+ L
Sbjct: 274 SVPEGL 279
Score = 41.5 bits (93), Expect = 0.008
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 3/128 (2%)
Query: 143 LQSLPSDLKLMPS-LQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
L LP++L S LQ L+ N ++SL E L+ L + L+ N + L F +
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPSGLFQAS 139
Query: 201 EKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L + N+L+ L S L LK+L +L+L+ N + + + L +DL NQ
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 260 ISLLTGSL 267
+ L L
Sbjct: 200 LETLPPDL 207
Score = 34.7 bits (76), Expect = 0.87
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 180 MRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTE 238
+ + + F + L + A KL EL ++ N L+ L+ LR + LR L+LT N +T
Sbjct: 71 VHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTG 130
Query: 239 FSLQEIKGLRRLSVIDLSHNQISLL 263
+ L + L NQ+ +L
Sbjct: 131 LPSGLFQASATLDTLVLKENQLEVL 155
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 67.3 bits (157), Expect = 1e-10
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 5/174 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N L L L+ +P ++ LDL RN +T L F+ L+ L++ +NQ+ +E
Sbjct: 99 LSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVS 158
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
L K L H+ L N+L L G L + L + + N L+++ +L +++ +H
Sbjct: 159 WLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLH 218
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKI 189
N+LQ L DL L P L+ L+ GN + + Q R L + LS N +
Sbjct: 219 LEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSL 272
Score = 56.0 bits (129), Expect = 3e-07
Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 4/180 (2%)
Query: 86 LKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ +HL N L +L+ LR + L + + N L + L + + + N+L+
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEK 202
L S L + +L L GN ++ L L + L+R + L N++E L D +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 203 LAELDIAYNELKYLNGSLRSLK-SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N+L+ L L + LRYL L N + + +GLR+L ++DLS+N ++
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Score = 52.4 bits (120), Expect = 4e-06
Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L +F +D L +N L L L L + LDL N++ KL + L
Sbjct: 131 LPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLL 190
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L + +NQ+ + D L P L+ +HL NKL L L DL ++F+N N L
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL 150
+ +++ ++ ++N L S+P L
Sbjct: 251 VAAGAFQGLRQLDMLDLSNNSLASVPEGL 279
Score = 50.0 bits (114), Expect = 2e-05
Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ S L + + L+ N L +LP +L + ++TLDL N++ L + R +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 64 LEHLLVADNQISEIEKD-ALPK-GLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLK 120
LE L + N++ + KD LP+ L+++ L NKL GA + L L+ + ++ N+L
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 121 SIENEL 126
S+ L
Sbjct: 274 SVPEGL 279
Score = 41.1 bits (92), Expect = 0.010
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 3/128 (2%)
Query: 143 LQSLPSDLKLMPS-LQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
L LP++L S LQ L+ N ++SL E L+ L + L+ N + L F +
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 201 EKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L + N+L+ L S L LK+L +L+L+ N + + + L +DL NQ
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 260 ISLLTGSL 267
+ L L
Sbjct: 200 LETLPPDL 207
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 67.3 bits (157), Expect = 1e-10
Identities = 64/219 (29%), Positives = 103/219 (47%), Gaps = 8/219 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N + LP V Q L ++ LDL N++ ++T E FR ++ LE L + N+I I+
Sbjct: 11 LSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPG 70
Query: 81 ALP--KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHA 138
A L + L N+L L LR L L + ++ N+L ++E + A ++ +
Sbjct: 71 AFDTLDRLLELKLQDNELRAL-PPLR-LPRLLLLDLSHNSLLALEPGILDTA-NVEALRL 127
Query: 139 AHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN-KIEFLTKDD 196
A LQ L L + +L L N ++ + ++ R L R+ L+ N +I L +D
Sbjct: 128 AGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPED 187
Query: 197 FTEAEKLAELDIAYNELKYLNGSLRSL-KSLRYLNLTHN 234
L ELD++ L+ L G L L LR L N
Sbjct: 188 LAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARN 226
Score = 61.3 bits (142), Expect = 9e-09
Identities = 43/158 (27%), Positives = 84/158 (53%), Gaps = 7/158 (4%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGIN 94
LP ++ LDL +N+I L F+ + L +L + N++ EI + + L+ ++LG N
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 62
Query: 95 KLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLM 153
++ + GA LD L + + N L+++ P + ++ L+ +HN L +L +
Sbjct: 63 RIRHIQPGAFDTLDRLLELKLQDNELRALP---PLRLPRLLLLDLSHNSLLALEPGILDT 119
Query: 154 PSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIE 190
++++L G ++ LDE L + RNL + +S N++E
Sbjct: 120 ANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLE 157
Score = 48.0 bits (109), Expect = 9e-05
Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 153 MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+P LQ L N I SL Q NL + L+ N++ +T + F +L L + N
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKN 62
Query: 212 ELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
++++ G+ +L L L L N + +L ++ L RL ++DLSHN + L + +
Sbjct: 63 RIRHIQPGAFDTLDRLLELKLQDNELR--ALPPLR-LPRLLLLDLSHNSLLALEPGILDT 119
Query: 271 VDVE 274
+VE
Sbjct: 120 ANVE 123
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 1/160 (0%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L VF L + L N L E+ + L ++ L L +N+I + F + L
Sbjct: 19 LPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRL 78
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L + DN++ + LP+ L + L N L L + D ++E + + L+ ++
Sbjct: 79 LELKLQDNELRALPPLRLPR-LLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDE 137
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
L ++ + + + + N+L+ +P ++ + L L GN
Sbjct: 138 GLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGN 177
Score = 41.5 bits (93), Expect = 0.008
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
Query: 206 LDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
LD++ N++ L +G + L +L L+LT N + E + + +GLRRL + L N+I +
Sbjct: 9 LDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQ 68
Query: 265 GSLENLVDVETRVLELRLDHNHI 287
+ +D R+LEL+L N +
Sbjct: 69 PGAFDTLD---RLLELKLQDNEL 88
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 67.3 bits (157), Expect = 1e-10
Identities = 52/174 (29%), Positives = 85/174 (48%), Gaps = 5/174 (2%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L+ N L L L+ +P ++ LDL RN +T L F+ L+ L++ +NQ+ +E
Sbjct: 99 LSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVS 158
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
L K L H+ L N+L L G L + L + + N L+++ +L +++ +H
Sbjct: 159 WLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQLERLH 218
Query: 138 AAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKI 189
N+LQ L DL L P L+ L+ GN + + Q R L + LS N +
Sbjct: 219 LEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSL 272
Score = 56.0 bits (129), Expect = 3e-07
Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 4/180 (2%)
Query: 86 LKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ +HL N L +L+ LR + L + + N L + L + + + N+L+
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKDDFTEAEK 202
L S L + +L L GN ++ L L + L+R + L N++E L D +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 203 LAELDIAYNELKYLNGSLRSLK-SLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQIS 261
L L + N+L+ L L + LRYL L N + + +GLR+L ++DLS+N ++
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Score = 52.4 bits (120), Expect = 4e-06
Identities = 41/149 (27%), Positives = 66/149 (44%), Gaps = 3/149 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L +F +D L +N L L L L + LDL N++ KL + L
Sbjct: 131 LPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLL 190
Query: 65 EHLLVADNQISEIEKDAL--PKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
L + +NQ+ + D L P L+ +HL NKL L L DL ++F+N N L
Sbjct: 191 RTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLAR 250
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSDL 150
+ +++ ++ ++N L S+P L
Sbjct: 251 VAAGAFQGLRQLDMLDLSNNSLASVPEGL 279
Score = 50.0 bits (114), Expect = 2e-05
Identities = 38/126 (30%), Positives = 66/126 (52%), Gaps = 3/126 (2%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL+ S L + + L+ N L +LP +L + ++TLDL N++ L + R +
Sbjct: 154 VLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDLLRGPLQ 213
Query: 64 LEHLLVADNQISEIEKD-ALPK-GLKHVHLGINKL-NTLNGALRDLDDLEWIFINANNLK 120
LE L + N++ + KD LP+ L+++ L NKL GA + L L+ + ++ N+L
Sbjct: 214 LERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
Query: 121 SIENEL 126
S+ L
Sbjct: 274 SVPEGL 279
Score = 41.1 bits (92), Expect = 0.010
Identities = 38/128 (29%), Positives = 60/128 (46%), Gaps = 3/128 (2%)
Query: 143 LQSLPSDLKLMPS-LQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
L LP++L S LQ L+ N ++SL E L+ L + L+ N + L F +
Sbjct: 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query: 201 EKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L + N+L+ L S L LK+L +L+L+ N + + + L +DL NQ
Sbjct: 140 ATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQ 199
Query: 260 ISLLTGSL 267
+ L L
Sbjct: 200 LETLPPDL 207
>AY899849-1|AAX85197.1| 709|Homo sapiens LGR7.2 protein.
Length = 709
Score = 66.9 bits (156), Expect = 2e-10
Identities = 60/207 (28%), Positives = 94/207 (45%), Gaps = 10/207 (4%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP--KGLKHVHLGINKL 96
+V + L N I KL + F++ +L+ L + +N+I+ I A L ++L N++
Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSD--LKLM 153
L G DL LEW+ I N+L I + L+ +N L LP + M
Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246
Query: 154 PSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
P L L GN+I +L T NL + + NKI L ++ F +KL E + E
Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEFSLEGIE 306
Query: 213 LKYLNGSLRSLKSLRYLNLTHNYMTEF 239
+ N R + L +NL+H Y +F
Sbjct: 307 IS--NIQQRMFRPL--MNLSHIYFKKF 329
Score = 38.7 bits (86), Expect = 0.054
Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 10/178 (5%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L +N + + + + L + L L N+IT L F D+ LE L++ DN +S I
Sbjct: 157 LQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPP 216
Query: 81 ALPKGLKHVHLGINKLNTL-----NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
GL + L + N L + + L W+ + N++ ++ N + +
Sbjct: 217 TF-YGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTV 275
Query: 136 IHAAHNELQSL-PSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIG-LSFNKIEF 191
+ N++ L + + L G I ++ + + R LM + + F K ++
Sbjct: 276 LVMRKNKINHLNENTFAPLQKLDEFSLEGIEISNIQQRM--FRPLMNLSHIYFKKFQY 331
Score = 35.5 bits (78), Expect = 0.50
Identities = 20/60 (33%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 221 RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGSLENLVDVETRVLE 279
++ L+ L L +N +T S+ +GL L+ + LSHN+I+ L G E+L +E ++E
Sbjct: 147 KNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRITFLKPGVFEDLHRLEWLIIE 206
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 66.5 bits (155), Expect = 2e-10
Identities = 48/190 (25%), Positives = 95/190 (50%), Gaps = 6/190 (3%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
VF L V Y +L N L L + ++ LDL N I +++E F+ ++ L L
Sbjct: 151 VFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLY 210
Query: 69 VADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENE 125
+ N ++++ +A K L+ + L N + + A + L +LE++ + + ++++ +
Sbjct: 211 LGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRD 270
Query: 126 LPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLD-ETLQK-SRNLMRI 182
+ ++ + +HN+L++L SD L+ +L L N I S+D +T + +L +
Sbjct: 271 GFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKIL 330
Query: 183 GLSFNKIEFL 192
LSFN + L
Sbjct: 331 NLSFNNLTAL 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/252 (22%), Positives = 113/252 (44%), Gaps = 11/252 (4%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH---LGINKLNTL 99
L L N I+ + E + + L L + ++ I + A + L+H++ L N + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQ-LRHLYFLFLNNNFIKRL 123
Query: 100 N-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQ 157
+ G + L +L +++ N + + + +Q ++ N L L S + M +L+
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 158 SLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
L NNI + E+ Q NL + L N + + + F + L L +++N ++ +
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 217 NG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ + L +L YL L ++ + + G+ L + LSHN + L +L+
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLL---K 300
Query: 276 RVLELRLDHNHI 287
++ L+LD N I
Sbjct: 301 NLIYLKLDRNRI 312
Score = 56.8 bits (131), Expect = 2e-07
Identities = 57/239 (23%), Positives = 110/239 (46%), Gaps = 25/239 (10%)
Query: 24 NSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP 83
N + +PR V L V+ L+L RN++T L F + L L +++N I I +
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISE---- 197
Query: 84 KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
G +H L++L +++ +NNL + + K ++ + +HN +
Sbjct: 198 SGFQH-----------------LENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPI 240
Query: 144 QSL-PSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
+++ P K + +L+ L + I+++ + NL + LS N +E L D F+ +
Sbjct: 241 EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLK 300
Query: 202 KLAELDIAYNELKYL-NGSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L L + N + + N + ++ SL+ LNL+ N +T + +K L L + + N
Sbjct: 301 NLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 55/237 (23%), Positives = 111/237 (46%), Gaps = 10/237 (4%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL F + + L++N++ + QHL ++ L L N +TK+ F ++
Sbjct: 170 VLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKS 229
Query: 64 LEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD----LDDLEWIFINANNL 119
L L ++ N I I+ A KGL ++ + K + + RD +++L+ + ++ N+L
Sbjct: 230 LRRLSLSHNPIEAIQPFAF-KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDL 288
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSL-DETLQKS 176
+++ ++ + K + + N + S+ +D + SL+ L NN+ +L L+
Sbjct: 289 ENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPL 348
Query: 177 RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+L+ + + N E K + LA I N S+R ++LRY+N+T+
Sbjct: 349 SSLIHLQANSNPWECNCK-LLGLRDWLASSAITLNIYCQNPPSMRG-RALRYINITN 403
Score = 52.4 bits (120), Expect = 4e-06
Identities = 54/275 (19%), Positives = 123/275 (44%), Gaps = 10/275 (3%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI 77
+ L N++ + L L + L L + I + + F ++ L L + +N I +
Sbjct: 64 FLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRL 123
Query: 78 EKDALPKGL---KHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKM 133
+ KGL ++++L N+++ + G DL ++++ + N L + + +
Sbjct: 124 DPGIF-KGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVAL 182
Query: 134 QLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEF 191
+++ ++N + + S + + +L LY NN+ + + ++L R+ LS N IE
Sbjct: 183 RILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEA 242
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
+ F L L + + ++ + + +L++L L+HN + + L+ L
Sbjct: 243 IQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNL 302
Query: 251 SVIDLSHNQ-ISLLTGSLENLVDVETRVLELRLDH 284
+ L N+ IS+ + EN+ ++L L ++
Sbjct: 303 IYLKLDRNRIISIDNDTFENM-GASLKILNLSFNN 336
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Query: 114 INANNL--KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-D 170
IN NL SI P + L +N S+L + SL +LY +NI +
Sbjct: 44 INCRNLGLSSIPKNFPESTVFLYL--TGNNISYINESELTGLHSLVALYLDNSNILYVYP 101
Query: 171 ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYL 229
+ + R+L + L+ N I+ L F L L + YN++ ++ G L S++YL
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENL 270
NL N +T G+ L ++DLS+N I ++ S LENL
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENL 206
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 66.5 bits (155), Expect = 2e-10
Identities = 48/190 (25%), Positives = 95/190 (50%), Gaps = 6/190 (3%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
VF L V Y +L N L L + ++ LDL N I +++E F+ ++ L L
Sbjct: 151 VFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLY 210
Query: 69 VADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENE 125
+ N ++++ +A K L+ + L N + + A + L +LE++ + + ++++ +
Sbjct: 211 LGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRD 270
Query: 126 LPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLD-ETLQK-SRNLMRI 182
+ ++ + +HN+L++L SD L+ +L L N I S+D +T + +L +
Sbjct: 271 GFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKIL 330
Query: 183 GLSFNKIEFL 192
LSFN + L
Sbjct: 331 NLSFNNLTAL 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/252 (22%), Positives = 113/252 (44%), Gaps = 11/252 (4%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH---LGINKLNTL 99
L L N I+ + E + + L L + ++ I + A + L+H++ L N + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQ-LRHLYFLFLNNNFIKRL 123
Query: 100 N-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQ 157
+ G + L +L +++ N + + + +Q ++ N L L S + M +L+
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 158 SLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
L NNI + E+ Q NL + L N + + + F + L L +++N ++ +
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 217 NG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ + L +L YL L ++ + + G+ L + LSHN + L +L+
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLL---K 300
Query: 276 RVLELRLDHNHI 287
++ L+LD N I
Sbjct: 301 NLIYLKLDRNRI 312
Score = 56.8 bits (131), Expect = 2e-07
Identities = 57/239 (23%), Positives = 110/239 (46%), Gaps = 25/239 (10%)
Query: 24 NSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP 83
N + +PR V L V+ L+L RN++T L F + L L +++N I I +
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISE---- 197
Query: 84 KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
G +H L++L +++ +NNL + + K ++ + +HN +
Sbjct: 198 SGFQH-----------------LENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPI 240
Query: 144 QSL-PSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
+++ P K + +L+ L + I+++ + NL + LS N +E L D F+ +
Sbjct: 241 EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLK 300
Query: 202 KLAELDIAYNELKYL-NGSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L L + N + + N + ++ SL+ LNL+ N +T + +K L L + + N
Sbjct: 301 NLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 55/237 (23%), Positives = 111/237 (46%), Gaps = 10/237 (4%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL F + + L++N++ + QHL ++ L L N +TK+ F ++
Sbjct: 170 VLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKS 229
Query: 64 LEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD----LDDLEWIFINANNL 119
L L ++ N I I+ A KGL ++ + K + + RD +++L+ + ++ N+L
Sbjct: 230 LRRLSLSHNPIEAIQPFAF-KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDL 288
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSL-DETLQKS 176
+++ ++ + K + + N + S+ +D + SL+ L NN+ +L L+
Sbjct: 289 ENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPL 348
Query: 177 RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+L+ + + N E K + LA I N S+R ++LRY+N+T+
Sbjct: 349 SSLIHLQANSNPWECNCK-LLGLRDWLASSAITLNIYCQNPPSMRG-RALRYINITN 403
Score = 52.4 bits (120), Expect = 4e-06
Identities = 54/275 (19%), Positives = 123/275 (44%), Gaps = 10/275 (3%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI 77
+ L N++ + L L + L L + I + + F ++ L L + +N I +
Sbjct: 64 FLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRL 123
Query: 78 EKDALPKGL---KHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKM 133
+ KGL ++++L N+++ + G DL ++++ + N L + + +
Sbjct: 124 DPGIF-KGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVAL 182
Query: 134 QLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEF 191
+++ ++N + + S + + +L LY NN+ + + ++L R+ LS N IE
Sbjct: 183 RILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEA 242
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
+ F L L + + ++ + + +L++L L+HN + + L+ L
Sbjct: 243 IQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNL 302
Query: 251 SVIDLSHNQ-ISLLTGSLENLVDVETRVLELRLDH 284
+ L N+ IS+ + EN+ ++L L ++
Sbjct: 303 IYLKLDRNRIISIDNDTFENM-GASLKILNLSFNN 336
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Query: 114 INANNL--KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-D 170
IN NL SI P + L +N S+L + SL +LY +NI +
Sbjct: 44 INCRNLGLSSIPKNFPESTVFLYL--TGNNISYINESELTGLHSLVALYLDNSNILYVYP 101
Query: 171 ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYL 229
+ + R+L + L+ N I+ L F L L + YN++ ++ G L S++YL
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENL 270
NL N +T G+ L ++DLS+N I ++ S LENL
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENL 206
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 66.5 bits (155), Expect = 2e-10
Identities = 48/190 (25%), Positives = 95/190 (50%), Gaps = 6/190 (3%)
Query: 9 VFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLL 68
VF L V Y +L N L L + ++ LDL N I +++E F+ ++ L L
Sbjct: 151 VFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLY 210
Query: 69 VADNQISEIEKDALP--KGLKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENE 125
+ N ++++ +A K L+ + L N + + A + L +LE++ + + ++++ +
Sbjct: 211 LGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRIRNVTRD 270
Query: 126 LPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLD-ETLQK-SRNLMRI 182
+ ++ + +HN+L++L SD L+ +L L N I S+D +T + +L +
Sbjct: 271 GFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKIL 330
Query: 183 GLSFNKIEFL 192
LSFN + L
Sbjct: 331 NLSFNNLTAL 340
Score = 57.2 bits (132), Expect = 1e-07
Identities = 57/252 (22%), Positives = 113/252 (44%), Gaps = 11/252 (4%)
Query: 43 LDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH---LGINKLNTL 99
L L N I+ + E + + L L + ++ I + A + L+H++ L N + L
Sbjct: 65 LYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQ-LRHLYFLFLNNNFIKRL 123
Query: 100 N-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQ 157
+ G + L +L +++ N + + + +Q ++ N L L S + M +L+
Sbjct: 124 DPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALR 183
Query: 158 SLYFYGNNIKSLDET-LQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL 216
L NNI + E+ Q NL + L N + + + F + L L +++N ++ +
Sbjct: 184 ILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAI 243
Query: 217 NG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
+ + L +L YL L ++ + + G+ L + LSHN + L +L+
Sbjct: 244 QPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLL---K 300
Query: 276 RVLELRLDHNHI 287
++ L+LD N I
Sbjct: 301 NLIYLKLDRNRI 312
Score = 56.8 bits (131), Expect = 2e-07
Identities = 57/239 (23%), Positives = 110/239 (46%), Gaps = 25/239 (10%)
Query: 24 NSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP 83
N + +PR V L V+ L+L RN++T L F + L L +++N I I +
Sbjct: 142 NQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISE---- 197
Query: 84 KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNEL 143
G +H L++L +++ +NNL + + K ++ + +HN +
Sbjct: 198 SGFQH-----------------LENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPI 240
Query: 144 QSL-PSDLKLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
+++ P K + +L+ L + I+++ + NL + LS N +E L D F+ +
Sbjct: 241 EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLK 300
Query: 202 KLAELDIAYNELKYL-NGSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
L L + N + + N + ++ SL+ LNL+ N +T + +K L L + + N
Sbjct: 301 NLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQANSN 359
Score = 54.8 bits (126), Expect = 8e-07
Identities = 55/237 (23%), Positives = 111/237 (46%), Gaps = 10/237 (4%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
VL F + + L++N++ + QHL ++ L L N +TK+ F ++
Sbjct: 170 VLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKS 229
Query: 64 LEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRD----LDDLEWIFINANNL 119
L L ++ N I I+ A KGL ++ + K + + RD +++L+ + ++ N+L
Sbjct: 230 LRRLSLSHNPIEAIQPFAF-KGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDL 288
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDL--KLMPSLQSLYFYGNNIKSL-DETLQKS 176
+++ ++ + K + + N + S+ +D + SL+ L NN+ +L L+
Sbjct: 289 ENLNSDTFSLLKNLIYLKLDRNRIISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPL 348
Query: 177 RNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+L+ + + N E K + LA I N S+R ++LRY+N+T+
Sbjct: 349 SSLIHLQANSNPWECNCK-LLGLRDWLASSAITLNIYCQNPPSMRG-RALRYINITN 403
Score = 52.4 bits (120), Expect = 4e-06
Identities = 54/275 (19%), Positives = 123/275 (44%), Gaps = 10/275 (3%)
Query: 18 YFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI 77
+ L N++ + L L + L L + I + + F ++ L L + +N I +
Sbjct: 64 FLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRL 123
Query: 78 EKDALPKGL---KHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKM 133
+ KGL ++++L N+++ + G DL ++++ + N L + + +
Sbjct: 124 DPGIF-KGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVAL 182
Query: 134 QLIHAAHNELQSLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEF 191
+++ ++N + + S + + +L LY NN+ + + ++L R+ LS N IE
Sbjct: 183 RILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEA 242
Query: 192 LTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
+ F L L + + ++ + + +L++L L+HN + + L+ L
Sbjct: 243 IQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNL 302
Query: 251 SVIDLSHNQ-ISLLTGSLENLVDVETRVLELRLDH 284
+ L N+ IS+ + EN+ ++L L ++
Sbjct: 303 IYLKLDRNRIISIDNDTFENM-GASLKILNLSFNN 336
Score = 49.6 bits (113), Expect = 3e-05
Identities = 49/165 (29%), Positives = 76/165 (46%), Gaps = 10/165 (6%)
Query: 114 INANNL--KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSL-D 170
IN NL SI P + L +N S+L + SL +LY +NI +
Sbjct: 44 INCRNLGLSSIPKNFPESTVFLYL--TGNNISYINESELTGLHSLVALYLDNSNILYVYP 101
Query: 171 ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYL 229
+ + R+L + L+ N I+ L F L L + YN++ ++ G L S++YL
Sbjct: 102 KAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYL 161
Query: 230 NLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS----LENL 270
NL N +T G+ L ++DLS+N I ++ S LENL
Sbjct: 162 NLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENL 206
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 65.7 bits (153), Expect = 4e-10
Identities = 61/214 (28%), Positives = 98/214 (45%), Gaps = 19/214 (8%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L N L LPR + PH++ LD+ N +T L E ++ L LL +N++
Sbjct: 83 LPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPE-LLALRGLRTLLAKNNRLGG--PS 139
Query: 81 ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
ALPKGL L L LN ++ N + + L + + +Q +
Sbjct: 140 ALPKGLAQSPL-CRSLQVLN-------------LSGNCFQEVPASL-LELRALQTLSLGG 184
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEA 200
N+LQS+P++++ + SL+ LY GN IK + L +L + L NKI+ + ++
Sbjct: 185 NQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSI-PPQLSQL 243
Query: 201 EKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L L + N L YL + +L L L+L N
Sbjct: 244 HSLRSLSLHNNLLTYLPREILNLIHLEELSLRGN 277
>U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein.
Length = 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 58/237 (24%), Positives = 113/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L +N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 58/237 (24%), Positives = 113/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L +N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 58/237 (24%), Positives = 113/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L +N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 58/237 (24%), Positives = 113/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L +N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich end
leucine-rich repeat protein protein.
Length = 382
Score = 65.3 bits (152), Expect = 5e-10
Identities = 58/237 (24%), Positives = 113/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L +N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 58.0 bits (134), Expect = 8e-08
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein.
Length = 382
Score = 64.9 bits (151), Expect = 7e-10
Identities = 58/237 (24%), Positives = 112/237 (47%), Gaps = 18/237 (7%)
Query: 16 VDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQIS 75
+ Y L N + ELP Q+ ++ ++L N+I K+ + + L L + NQ+
Sbjct: 104 IHYLYLQSNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163
Query: 76 EIEKDALPKGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKS--IENELPTKAKK 132
E+ ALP+ L+ + L N ++ + G L++L + + N L + + K
Sbjct: 164 EV-PSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKS-RNLMRIGLSFNKI-- 189
+ ++ AHN L+ +P ++ ++ LY N I+++ KS NL I L++NK+
Sbjct: 223 LMQLNLAHNILRKMPP--RVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD 280
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKG 246
L K+ F L L +++N + S+ ++ + L H Y+ S+++I G
Sbjct: 281 RGLPKNSF-NISNLLVLHLSHNRI----SSVPAINN----RLEHLYLNNNSIEKING 328
Score = 57.6 bits (133), Expect = 1e-07
Identities = 59/236 (25%), Positives = 115/236 (48%), Gaps = 15/236 (6%)
Query: 38 PHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINK 95
P + L L N IT+L E F++ L + + +N+I +I++ L K GL +++ N+
Sbjct: 102 PRIHYLYLQSNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161
Query: 96 LNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQS---LPSDLKL 152
L + AL +LE + ++ N++ I + +K + + L+ HN L P
Sbjct: 162 LEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
+ +L L N ++ + + + + ++ L NKIE + F LA + + YN+
Sbjct: 220 LKNLMQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277
Query: 213 L--KYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGS 266
L + L + ++ +L L+L+HN ++ S+ I RL + L++N I + G+
Sbjct: 278 LTDRGLPKNSFNISNLLVLHLSHNRIS--SVPAIN--NRLEHLYLNNNSIEKINGT 329
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 64.5 bits (150), Expect = 9e-10
Identities = 59/253 (23%), Positives = 116/253 (45%), Gaps = 8/253 (3%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
+SL N + + L ++ LDL N+I L + F + LE L + +N + +
Sbjct: 64 YSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALA 123
Query: 79 KDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
L + L+ ++ N+++ L+ G+ L+ L + ++ N L ++ + + +
Sbjct: 124 PGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLY 183
Query: 136 IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIK-SLDE--TLQKSRNLMRIGLSFNKIEF 191
+H N ++ L + + L+ L N ++ SL T R+L + LS N ++
Sbjct: 184 LHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQH 243
Query: 192 LTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
L F +L L + N+L +L + L++LR L L N +++ ++ L L
Sbjct: 244 LGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSL 303
Query: 251 SVIDLSHNQISLL 263
+DLS N++S L
Sbjct: 304 EALDLSGNELSAL 316
Score = 61.3 bits (142), Expect = 9e-09
Identities = 68/248 (27%), Positives = 109/248 (43%), Gaps = 12/248 (4%)
Query: 38 PH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGIN 94
PH V T L N IT +T DF + +L L + NQI + K L+ ++LG N
Sbjct: 58 PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNN 117
Query: 95 KLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLM 153
L L G L L L ++ N N + + + + + N L +LP D
Sbjct: 118 LLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALP-DAVFA 176
Query: 154 P--SLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD--DFTEAEKLAELDI 208
P +L L+ N I+ L + +R + LS N+++ + F L+ L +
Sbjct: 177 PLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLIL 236
Query: 209 AYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGS 266
+ N L++L + + L L L+L N +T + + GL L + L N++S L T
Sbjct: 237 SANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTAL 296
Query: 267 LENLVDVE 274
LE L +E
Sbjct: 297 LEPLHSLE 304
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/208 (26%), Positives = 103/208 (49%), Gaps = 9/208 (4%)
Query: 86 LKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ + L N++ +L+ L LE +++ N L+++ +K+++++A NE+
Sbjct: 85 LRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEIS 144
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L + + SL L GN + +L D NL+ + L N+I FL K+ F + K
Sbjct: 145 RLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGK 204
Query: 203 LAELDIAYNELK---YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L+++ NEL+ + L+SL L L+ N + + + L RL ++ L NQ
Sbjct: 205 LRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQ 264
Query: 260 ISLLTGSLENLVDVETRVLELRLDHNHI 287
++ L + E +E + ELRL+ N +
Sbjct: 265 LTHL--APEAFWGLEA-LRELRLEGNRL 289
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 8 SVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL 67
+ F L + L+ NSL L + QHLP + L L N++T L E F ++ L L
Sbjct: 223 ATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALREL 282
Query: 68 LVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIEN 124
+ N++S++ L L+ + L N+L+ L+ A L L + + N L ++
Sbjct: 283 RLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSG 342
Query: 125 EL 126
++
Sbjct: 343 DI 344
Score = 44.8 bits (101), Expect = 8e-04
Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 6/116 (5%)
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLN 230
+L +++ L N I +T DF +L LD+ YN+++ L+ + L L L
Sbjct: 54 SLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELY 113
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVETRVLELRLDHN 285
L +N + + + LR+L ++ + N+IS L+ GS E L +++LRLD N
Sbjct: 114 LGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGL----ESLVKLRLDGN 165
Score = 44.8 bits (101), Expect = 8e-04
Identities = 52/214 (24%), Positives = 89/214 (41%), Gaps = 7/214 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L F L+ + L N+L LP V L ++ L L N+I L + F + +L
Sbjct: 146 LSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKL 205
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNL 119
L ++ N++ + A + L + L N L L + + L L + + N L
Sbjct: 206 RFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQL 265
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSR 177
+ E + ++ + N L LP+ L+ + SL++L GN + +L T
Sbjct: 266 THLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLG 325
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L + L N + L+ D F + L LD+ N
Sbjct: 326 RLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359
>BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine rich
transmembrane protein 1 protein.
Length = 674
Score = 64.5 bits (150), Expect = 9e-10
Identities = 61/233 (26%), Positives = 112/233 (48%), Gaps = 11/233 (4%)
Query: 42 TLDLCRNKITKL-TEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTL- 99
TL L N+I +D + ++ + + +N + E + LP+ L+ +HL N + T+
Sbjct: 85 TLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPIN-LPRSLRELHLQDNNVRTIA 143
Query: 100 NGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
+L + LE + ++ N++ SIE + +K+++L+ + N L S+PS L +L+
Sbjct: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLP--HTLE 201
Query: 158 SLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELK 214
L N I ++ K N L R+ L N + + + D F+ + L EL + N L
Sbjct: 202 ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLA 261
Query: 215 YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+L S L+ L L N ++ + +R L +DLS+N ++ L L
Sbjct: 262 APPLNLPS-AHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGL 313
Score = 35.5 bits (78), Expect = 0.50
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L DN++ +P + L + ++ LDL N +T L F D+ L LL+ +N
Sbjct: 277 LQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
>AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein.
Length = 674
Score = 64.5 bits (150), Expect = 9e-10
Identities = 61/233 (26%), Positives = 112/233 (48%), Gaps = 11/233 (4%)
Query: 42 TLDLCRNKITKL-TEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTL- 99
TL L N+I +D + ++ + + +N + E + LP+ L+ +HL N + T+
Sbjct: 85 TLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPIN-LPRSLRELHLQDNNVRTIA 143
Query: 100 NGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
+L + LE + ++ N++ SIE + +K+++L+ + N L S+PS L +L+
Sbjct: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLP--HTLE 201
Query: 158 SLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELK 214
L N I ++ K N L R+ L N + + + D F+ + L EL + N L
Sbjct: 202 ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLA 261
Query: 215 YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+L S L+ L L N ++ + +R L +DLS+N ++ L L
Sbjct: 262 APPLNLPS-AHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGL 313
Score = 35.5 bits (78), Expect = 0.50
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L DN++ +P + L + ++ LDL N +T L F D+ L LL+ +N
Sbjct: 277 LQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
>AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat
transmembrane protein FLRT1 protein.
Length = 674
Score = 64.5 bits (150), Expect = 9e-10
Identities = 61/233 (26%), Positives = 112/233 (48%), Gaps = 11/233 (4%)
Query: 42 TLDLCRNKITKL-TEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTL- 99
TL L N+I +D + ++ + + +N + E + LP+ L+ +HL N + T+
Sbjct: 85 TLYLQNNQINNAGIPQDLKTKVNVQVIYLYENDLDEFPIN-LPRSLRELHLQDNNVRTIA 143
Query: 100 NGALRDLDDLEWIFINANNLK--SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
+L + LE + ++ N++ SIE + +K+++L+ + N L S+PS L +L+
Sbjct: 144 RDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLP--HTLE 201
Query: 158 SLYFYGNNIKSLDETLQKSRN-LMRIGLSFNKI--EFLTKDDFTEAEKLAELDIAYNELK 214
L N I ++ K N L R+ L N + + + D F+ + L EL + N L
Sbjct: 202 ELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLA 261
Query: 215 YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+L S L+ L L N ++ + +R L +DLS+N ++ L L
Sbjct: 262 APPLNLPS-AHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGL 313
Score = 35.5 bits (78), Expect = 0.50
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L DN++ +P + L + ++ LDL N +T L F D+ L LL+ +N
Sbjct: 277 LQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNN 328
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 64.5 bits (150), Expect = 9e-10
Identities = 59/253 (23%), Positives = 116/253 (45%), Gaps = 8/253 (3%)
Query: 19 FSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIE 78
+SL N + + L ++ LDL N+I L + F + LE L + +N + +
Sbjct: 140 YSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALA 199
Query: 79 KDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQL 135
L + L+ ++ N+++ L+ G+ L+ L + ++ N L ++ + + +
Sbjct: 200 PGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLY 259
Query: 136 IHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIK-SLDE--TLQKSRNLMRIGLSFNKIEF 191
+H N ++ L + + L+ L N ++ SL T R+L + LS N ++
Sbjct: 260 LHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQH 319
Query: 192 LTKDDFTEAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRL 250
L F +L L + N+L +L + L++LR L L N +++ ++ L L
Sbjct: 320 LGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSL 379
Query: 251 SVIDLSHNQISLL 263
+DLS N++S L
Sbjct: 380 EALDLSGNELSAL 392
Score = 61.3 bits (142), Expect = 9e-09
Identities = 68/248 (27%), Positives = 109/248 (43%), Gaps = 12/248 (4%)
Query: 38 PH-VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGIN 94
PH V T L N IT +T DF + +L L + NQI + K L+ ++LG N
Sbjct: 134 PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNN 193
Query: 95 KLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLM 153
L L G L L L ++ N N + + + + + N L +LP D
Sbjct: 194 LLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALP-DAVFA 252
Query: 154 P--SLQSLYFYGNNIKSLDETLQKSRNLMR-IGLSFNKIEFLTKD--DFTEAEKLAELDI 208
P +L L+ N I+ L + +R + LS N+++ + F L+ L +
Sbjct: 253 PLGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLIL 312
Query: 209 AYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL-TGS 266
+ N L++L + + L L L+L N +T + + GL L + L N++S L T
Sbjct: 313 SANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTAL 372
Query: 267 LENLVDVE 274
LE L +E
Sbjct: 373 LEPLHSLE 380
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/208 (26%), Positives = 103/208 (49%), Gaps = 9/208 (4%)
Query: 86 LKHVHLGINKLNTLNG-ALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQ 144
L+ + L N++ +L+ L LE +++ N L+++ +K+++++A NE+
Sbjct: 161 LRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILYANGNEIS 220
Query: 145 SLP-SDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
L + + SL L GN + +L D NL+ + L N+I FL K+ F + K
Sbjct: 221 RLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGK 280
Query: 203 LAELDIAYNELK---YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L+++ NEL+ + L+SL L L+ N + + + L RL ++ L NQ
Sbjct: 281 LRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQ 340
Query: 260 ISLLTGSLENLVDVETRVLELRLDHNHI 287
++ L + E +E + ELRL+ N +
Sbjct: 341 LTHL--APEAFWGLEA-LRELRLEGNRL 365
Score = 45.2 bits (102), Expect = 6e-04
Identities = 33/122 (27%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 8 SVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL 67
+ F L + L+ NSL L + QHLP + L L N++T L E F ++ L L
Sbjct: 299 ATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQLTHLAPEAFWGLEALREL 358
Query: 68 LVADNQISEIEKDALP--KGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSIEN 124
+ N++S++ L L+ + L N+L+ L+ A L L + + N L ++
Sbjct: 359 RLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNALSALSG 418
Query: 125 EL 126
++
Sbjct: 419 DI 420
Score = 44.8 bits (101), Expect = 8e-04
Identities = 34/116 (29%), Positives = 59/116 (50%), Gaps = 6/116 (5%)
Query: 172 TLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLN 230
+L +++ L N I +T DF +L LD+ YN+++ L+ + L L L
Sbjct: 130 SLPSPHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELY 189
Query: 231 LTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT-GSLENLVDVETRVLELRLDHN 285
L +N + + + LR+L ++ + N+IS L+ GS E L +++LRLD N
Sbjct: 190 LGNNLLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGL----ESLVKLRLDGN 241
Score = 44.8 bits (101), Expect = 8e-04
Identities = 52/214 (24%), Positives = 89/214 (41%), Gaps = 7/214 (3%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L F L+ + L N+L LP V L ++ L L N+I L + F + +L
Sbjct: 222 LSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKNAFAQLGKL 281
Query: 65 EHLLVADNQISEIEKDALP----KGLKHVHLGINKLNTLNGAL-RDLDDLEWIFINANNL 119
L ++ N++ + A + L + L N L L + + L L + + N L
Sbjct: 282 RFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHLPRLGLLSLRGNQL 341
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSL-DETLQKSR 177
+ E + ++ + N L LP+ L+ + SL++L GN + +L T
Sbjct: 342 THLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLG 401
Query: 178 NLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L + L N + L+ D F + L LD+ N
Sbjct: 402 RLRELSLRNNALSALSGDIFAASPALYRLDLDGN 435
>Z50749-1|CAA90626.1| 360|Homo sapiens yeast sds22 homolog protein.
Length = 360
Score = 63.7 bits (148), Expect = 2e-09
Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 31/246 (12%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKL 96
L VKTL L +N I + E+ ++Q L L + DNQI +IE L+ + + N L
Sbjct: 97 LKKVKTLCLRQNLIKCI--ENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLL 154
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ G + L L+ +F+ N + IEN + ++Q++ N ++++ ++ + +L
Sbjct: 155 RNIEG-VDKLTRLKKLFLVNNKISKIEN--LSNLHQLQMLELGSNRIRAI-ENIDTLTNL 210
Query: 157 QSLYFYGNNIKSLD---------------------ETLQKSRNLMRIGLSFNKIEFLTKD 195
+SL+ N I L E LQ NL + LS N IE + +
Sbjct: 211 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVI--E 268
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS-LQEIKGLRRLSVID 254
KL LDIA N +K + ++ L L+ + N + +S L E+KG R L +
Sbjct: 269 GLENNNKLTMLDIASNRIKKIE-NISHLTELQEFWMNDNLLESWSDLDELKGARSLETVY 327
Query: 255 LSHNQI 260
L N +
Sbjct: 328 LERNPL 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 57/233 (24%), Positives = 116/233 (49%), Gaps = 20/233 (8%)
Query: 55 EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
EE + E EH L D + +++DA L H +G K+ L ++ + +
Sbjct: 52 EERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIG--KIE----GFEVLKKVKTLCL 105
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
N +K IEN + + ++ + N+++ + +L+ + L+ L N ++++ E +
Sbjct: 106 RQNLIKCIEN--LEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNI-EGVD 161
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
K L ++ L NKI + ++ + +L L++ N ++ + ++ +L +L L L N
Sbjct: 162 KLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIE-NIDTLTNLESLFLGKN 218
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+T+ LQ + L L+V+ + N+++ + G L+NLV++ EL L HN I
Sbjct: 219 KITK--LQNLDALTNLTVLSMQSNRLTKIEG-LQNLVNLR----ELYLSHNGI 264
>BT020134-1|AAV38936.1| 360|Homo sapiens protein phosphatase 1,
regulatory subunit 7 protein.
Length = 360
Score = 63.7 bits (148), Expect = 2e-09
Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 31/246 (12%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKL 96
L VKTL L +N I + E+ ++Q L L + DNQI +IE L+ + + N L
Sbjct: 97 LKKVKTLCLRQNLIKCI--ENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLL 154
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ G + L L+ +F+ N + IEN + ++Q++ N ++++ ++ + +L
Sbjct: 155 RNIEG-VDKLTRLKKLFLVNNKISKIEN--LSNLHQLQMLELGSNRIRAI-ENIDTLTNL 210
Query: 157 QSLYFYGNNIKSLD---------------------ETLQKSRNLMRIGLSFNKIEFLTKD 195
+SL+ N I L E LQ NL + LS N IE + +
Sbjct: 211 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVI--E 268
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS-LQEIKGLRRLSVID 254
KL LDIA N +K + ++ L L+ + N + +S L E+KG R L +
Sbjct: 269 GLENNNKLTMLDIASNRIKKIE-NISHLTELQEFWMNDNLLESWSDLDELKGARSLETVY 327
Query: 255 LSHNQI 260
L N +
Sbjct: 328 LERNPL 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 57/233 (24%), Positives = 116/233 (49%), Gaps = 20/233 (8%)
Query: 55 EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
EE + E EH L D + +++DA L H +G K+ L ++ + +
Sbjct: 52 EERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIG--KIE----GFEVLKKVKTLCL 105
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
N +K IEN + + ++ + N+++ + +L+ + L+ L N ++++ E +
Sbjct: 106 RQNLIKCIEN--LEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNI-EGVD 161
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
K L ++ L NKI + ++ + +L L++ N ++ + ++ +L +L L L N
Sbjct: 162 KLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIE-NIDTLTNLESLFLGKN 218
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+T+ LQ + L L+V+ + N+++ + G L+NLV++ EL L HN I
Sbjct: 219 KITK--LQNLDALTNLTVLSMQSNRLTKIEG-LQNLVNLR----ELYLSHNGI 264
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/239 (25%), Positives = 111/239 (46%), Gaps = 6/239 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHL 91
L+ L +K L L R+ K+ L+ L + ++ + ++L K L+ + L
Sbjct: 267 LRELKQLKVLSL-RSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELEL 325
Query: 92 GINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
L + A+ L L+ + + N+L+SIE L + +K+ + HN++ +P +
Sbjct: 326 VACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHV 385
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ + SL+ LY N +++L L L + +S N + L + + L L ++Y
Sbjct: 386 RKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL-PPEVGLLQNLQHLALSY 444
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N L+ L L + LR L L N +++ S + LR LS ++L N++ L L N
Sbjct: 445 NALEALPEELFFCRKLRTLLLGDNQLSQLS-PHVGALRALSRLELKGNRLEALPEELGN 502
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ +VF+ L + L DN L + + QH + TL L N+I + E R ++
Sbjct: 333 IPHAVFS-LGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEH-VRKLRS 390
Query: 64 LEHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L ++ N++ + L GL+ + + N L++L + L +L+ + ++ N L+++
Sbjct: 391 LEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEAL 450
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL +K++ + N+L L + + +L L GN +++L E L L +
Sbjct: 451 PEEL-FFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKA 509
Query: 183 GL 184
GL
Sbjct: 510 GL 511
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/239 (25%), Positives = 111/239 (46%), Gaps = 6/239 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHL 91
L+ L +K L L R+ K+ L+ L + ++ + ++L K L+ + L
Sbjct: 531 LRELKQLKVLSL-RSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELEL 589
Query: 92 GINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
L + A+ L L+ + + N+L+SIE L + +K+ + HN++ +P +
Sbjct: 590 VACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHV 649
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ + SL+ LY N +++L L L + +S N + L + + L L ++Y
Sbjct: 650 RKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL-PPEVGLLQNLQHLALSY 708
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N L+ L L + LR L L N +++ S + LR LS ++L N++ L L N
Sbjct: 709 NALEALPEELFFCRKLRTLLLGDNQLSQLS-PHVGALRALSRLELKGNRLEALPEELGN 766
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ +VF+ L + L DN L + + QH + TL L N+I + E R ++
Sbjct: 597 IPHAVFS-LGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEH-VRKLRS 654
Query: 64 LEHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L ++ N++ + L GL+ + + N L++L + L +L+ + ++ N L+++
Sbjct: 655 LEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEAL 714
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL +K++ + N+L L + + +L L GN +++L E L L +
Sbjct: 715 PEEL-FFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKA 773
Query: 183 GL 184
GL
Sbjct: 774 GL 775
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/239 (25%), Positives = 111/239 (46%), Gaps = 6/239 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHL 91
L+ L +K L L R+ K+ L+ L + ++ + ++L K L+ + L
Sbjct: 327 LRELKQLKVLSL-RSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELEL 385
Query: 92 GINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
L + A+ L L+ + + N+L+SIE L + +K+ + HN++ +P +
Sbjct: 386 VACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHV 445
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ + SL+ LY N +++L L L + +S N + L + + L L ++Y
Sbjct: 446 RKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL-PPEVGLLQNLQHLALSY 504
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N L+ L L + LR L L N +++ S + LR LS ++L N++ L L N
Sbjct: 505 NALEALPEELFFCRKLRTLLLGDNQLSQLS-PHVGALRALSRLELKGNRLEALPEELGN 562
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ +VF+ L + L DN L + + QH + TL L N+I + E R ++
Sbjct: 393 IPHAVFS-LGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEH-VRKLRS 450
Query: 64 LEHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L ++ N++ + L GL+ + + N L++L + L +L+ + ++ N L+++
Sbjct: 451 LEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEAL 510
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL +K++ + N+L L + + +L L GN +++L E L L +
Sbjct: 511 PEEL-FFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKA 569
Query: 183 GL 184
GL
Sbjct: 570 GL 571
>BC000910-1|AAH00910.1| 360|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 7 protein.
Length = 360
Score = 63.7 bits (148), Expect = 2e-09
Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 31/246 (12%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKL 96
L VKTL L +N I + E+ ++Q L L + DNQI +IE L+ + + N L
Sbjct: 97 LKKVKTLCLRQNLIKCI--ENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLL 154
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ G + L L+ +F+ N + IEN + ++Q++ N ++++ ++ + +L
Sbjct: 155 RNIEG-VDKLTRLKKLFLVNNKISKIEN--LSNLHQLQMLELGSNRIRAI-ENIDTLTNL 210
Query: 157 QSLYFYGNNIKSLD---------------------ETLQKSRNLMRIGLSFNKIEFLTKD 195
+SL+ N I L E LQ NL + LS N IE + +
Sbjct: 211 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVI--E 268
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS-LQEIKGLRRLSVID 254
KL LDIA N +K + ++ L L+ + N + +S L E+KG R L +
Sbjct: 269 GLENNNKLTMLDIASNRIKKIE-NISHLTELQEFWMNDNLLESWSDLDELKGARSLETVY 327
Query: 255 LSHNQI 260
L N +
Sbjct: 328 LERNPL 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 57/233 (24%), Positives = 116/233 (49%), Gaps = 20/233 (8%)
Query: 55 EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
EE + E EH L D + +++DA L H +G K+ L ++ + +
Sbjct: 52 EERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIG--KIE----GFEVLKKVKTLCL 105
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
N +K IEN + + ++ + N+++ + +L+ + L+ L N ++++ E +
Sbjct: 106 RQNLIKCIEN--LEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNI-EGVD 161
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
K L ++ L NKI + ++ + +L L++ N ++ + ++ +L +L L L N
Sbjct: 162 KLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIE-NIDTLTNLESLFLGKN 218
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+T+ LQ + L L+V+ + N+++ + G L+NLV++ EL L HN I
Sbjct: 219 KITK--LQNLDALTNLTVLSMQSNRLTKIEG-LQNLVNLR----ELYLSHNGI 264
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/239 (25%), Positives = 111/239 (46%), Gaps = 6/239 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHL 91
L+ L +K L L R+ K+ L+ L + ++ + ++L K L+ + L
Sbjct: 357 LRELKQLKVLSL-RSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELEL 415
Query: 92 GINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
L + A+ L L+ + + N+L+SIE L + +K+ + HN++ +P +
Sbjct: 416 VACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHV 475
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ + SL+ LY N +++L L L + +S N + L + + L L ++Y
Sbjct: 476 RKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL-PPEVGLLQNLQHLALSY 534
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N L+ L L + LR L L N +++ S + LR LS ++L N++ L L N
Sbjct: 535 NALEALPEELFFCRKLRTLLLGDNQLSQLS-PHVGALRALSRLELKGNRLEALPEELGN 592
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ +VF+ L + L DN L + + QH + TL L N+I + E R ++
Sbjct: 423 IPHAVFS-LGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEH-VRKLRS 480
Query: 64 LEHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L ++ N++ + L GL+ + + N L++L + L +L+ + ++ N L+++
Sbjct: 481 LEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEAL 540
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL +K++ + N+L L + + +L L GN +++L E L L +
Sbjct: 541 PEEL-FFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKA 599
Query: 183 GL 184
GL
Sbjct: 600 GL 601
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 63.7 bits (148), Expect = 2e-09
Identities = 60/239 (25%), Positives = 111/239 (46%), Gaps = 6/239 (2%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHL 91
L+ L +K L L R+ K+ L+ L + ++ + ++L K L+ + L
Sbjct: 179 LRELKQLKVLSL-RSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELEL 237
Query: 92 GINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK-AKKMQLIHAAHNELQSLPSDL 150
L + A+ L L+ + + N+L+SIE L + +K+ + HN++ +P +
Sbjct: 238 VACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHV 297
Query: 151 KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAY 210
+ + SL+ LY N +++L L L + +S N + L + + L L ++Y
Sbjct: 298 RKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSL-PPEVGLLQNLQHLALSY 356
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N L+ L L + LR L L N +++ S + LR LS ++L N++ L L N
Sbjct: 357 NALEALPEELFFCRKLRTLLLGDNQLSQLS-PHVGALRALSRLELKGNRLEALPEELGN 414
Score = 54.4 bits (125), Expect = 1e-06
Identities = 46/182 (25%), Positives = 88/182 (48%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ +VF+ L + L DN L + + QH + TL L N+I + E R ++
Sbjct: 245 IPHAVFS-LGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEH-VRKLRS 302
Query: 64 LEHLLVADNQISEIEKD-ALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L ++ N++ + L GL+ + + N L++L + L +L+ + ++ N L+++
Sbjct: 303 LEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEAL 362
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL +K++ + N+L L + + +L L GN +++L E L L +
Sbjct: 363 PEEL-FFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKA 421
Query: 183 GL 184
GL
Sbjct: 422 GL 423
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/273 (23%), Positives = 132/273 (48%), Gaps = 18/273 (6%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L+ + +N + L L+HL + LDL NK+ + +E ++ LE L +
Sbjct: 43 FPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIIL-LRSLERLDL 101
Query: 70 ADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTK 129
++N IS + LK + L N L T+ + E + + +K ++ P++
Sbjct: 102 SNNDISSLPYSLGNLHLKFLALEGNPLRTIRREIISKGTQEVLKYLRSTIK---DDGPSQ 158
Query: 130 AKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYF--YGNNIKSL--DETLQ--KSRNLMRI 182
++ +A +LPS+ ++ + ++ +L Y + +L DE KS + I
Sbjct: 159 SE------SATETAMTLPSESRVNIHAIITLKILDYSDKQATLIPDEVFDAVKSNIVTSI 212
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ + K E ++++D+++N+L +++ L L+ L +L+L +N++ +
Sbjct: 213 NFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLELCVLQKLTFLDLRNNFLNSLP-E 271
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVET 275
E++ L RL I+LS N+ +L L + +ET
Sbjct: 272 EMESLVRLQTINLSFNRFKMLPEVLYRIFTLET 304
Score = 50.8 bits (116), Expect = 1e-05
Identities = 39/165 (23%), Positives = 86/165 (52%), Gaps = 6/165 (3%)
Query: 4 VLKESVF--TKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDI 61
++ + VF K ++V + + N L E+P+ +++ V +DL NK++ ++ E +
Sbjct: 195 LIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISLE-LCVL 253
Query: 62 QELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNL 119
Q+L L + +N ++ + E ++L + L+ ++L N+ L L + LE I I+ N +
Sbjct: 254 QKLTFLDLRNNFLNSLPEEMESLVR-LQTINLSFNRFKMLPEVLYRIFTLETILISNNQV 312
Query: 120 KSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGN 164
S++ + + + + +N+L +P +L +L++L GN
Sbjct: 313 GSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGN 357
Score = 46.8 bits (106), Expect = 2e-04
Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 4/119 (3%)
Query: 153 MPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNE 212
M L+ L N ++++ L +L + L NK+ FL +F L EL + N+
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLP--EFPSCSLLKELHVGENQ 58
Query: 213 LKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENL 270
++ L L+ L S+ L+L N + EI LR L +DLS+N IS L SL NL
Sbjct: 59 IEMLEAEHLKHLNSILVLDLRDNKLKSVP-DEIILLRSLERLDLSNNDISSLPYSLGNL 116
Score = 45.2 bits (102), Expect = 6e-04
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 1/121 (0%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N L I EL +K+ + +N L SLP +++ + LQ++ N K L E L
Sbjct: 238 LSFNKLSFISLELCV-LQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVL 296
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
+ L I +S N++ + E L LD+ N+L + L + +LR L L
Sbjct: 297 YRIFTLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDG 356
Query: 234 N 234
N
Sbjct: 357 N 357
Score = 40.3 bits (90), Expect = 0.018
Identities = 47/204 (23%), Positives = 90/204 (44%), Gaps = 33/204 (16%)
Query: 84 KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK--------SIENELPTKAKKMQL 135
K LKH+ N L T+ L ++ LE +++ N L+ S+ EL ++++
Sbjct: 2 KRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPEFPSCSLLKELHVGENQIEM 61
Query: 136 IHAAH--------------NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMR 181
+ A H N+L+S+P ++ L+ SL+ L N+I SL +L + +L
Sbjct: 62 LEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYSL-GNLHLKF 120
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMT--EF 239
+ L N + + ++ ++ + LKYL +++ + + T MT
Sbjct: 121 LALEGNPLRTIRREIISKGTQ--------EVLKYLRSTIKDDGPSQSESATETAMTLPSE 172
Query: 240 SLQEIKGLRRLSVIDLSHNQISLL 263
S I + L ++D S Q +L+
Sbjct: 173 SRVNIHAIITLKILDYSDKQATLI 196
>AF067136-2|AAD26610.1| 317|Homo sapiens protein phosphatase-1
regulatory subunit 7 alpha2 protein.
Length = 317
Score = 63.7 bits (148), Expect = 2e-09
Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 31/246 (12%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKL 96
L VKTL L +N I + E+ ++Q L L + DNQI +IE L+ + + N L
Sbjct: 54 LKKVKTLCLRQNLIKCI--ENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLL 111
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ G + L L+ +F+ N + IEN + ++Q++ N ++++ ++ + +L
Sbjct: 112 RNIEG-VDKLTRLKKLFLVNNKISKIEN--LSNLHQLQMLELGSNRIRAI-ENIDTLTNL 167
Query: 157 QSLYFYGNNIKSLD---------------------ETLQKSRNLMRIGLSFNKIEFLTKD 195
+SL+ N I L E LQ NL + LS N IE + +
Sbjct: 168 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVI--E 225
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS-LQEIKGLRRLSVID 254
KL LDIA N +K + ++ L L+ + N + +S L E+KG R L +
Sbjct: 226 GLENNNKLTMLDIASNRIKKIE-NISHLTELQEFWMNDNLLESWSDLDELKGARSLETVY 284
Query: 255 LSHNQI 260
L N +
Sbjct: 285 LERNPL 290
Score = 56.0 bits (129), Expect = 3e-07
Identities = 55/233 (23%), Positives = 118/233 (50%), Gaps = 20/233 (8%)
Query: 55 EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
++ +++ E EH L D + +++DA L H +G K+ L ++ + +
Sbjct: 9 QQQSQEMMEEEHELPVDMETINLDRDAEDVDLNHYRIG--KIE----GFEVLKKVKTLCL 62
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
N +K IEN + + ++ + N+++ + +L+ + L+ L N ++++ E +
Sbjct: 63 RQNLIKCIEN--LEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNI-EGVD 118
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
K L ++ L NKI + ++ + +L L++ N ++ + ++ +L +L L L N
Sbjct: 119 KLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIE-NIDTLTNLESLFLGKN 175
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+T+ LQ + L L+V+ + N+++ + G L+NLV++ EL L HN I
Sbjct: 176 KITK--LQNLDALTNLTVLSMQSNRLTKIEG-LQNLVNLR----ELYLSHNGI 221
>AF067136-1|AAD26611.1| 360|Homo sapiens protein phosphatase-1
regulatory subunit 7 alpha1 protein.
Length = 360
Score = 63.7 bits (148), Expect = 2e-09
Identities = 67/246 (27%), Positives = 112/246 (45%), Gaps = 31/246 (12%)
Query: 37 LPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKL 96
L VKTL L +N I + E+ ++Q L L + DNQI +IE L+ + + N L
Sbjct: 97 LKKVKTLCLRQNLIKCI--ENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLL 154
Query: 97 NTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSL 156
+ G + L L+ +F+ N + IEN + ++Q++ N ++++ ++ + +L
Sbjct: 155 RNIEG-VDKLTRLKKLFLVNNKISKIEN--LSNLHQLQMLELGSNRIRAI-ENIDTLTNL 210
Query: 157 QSLYFYGNNIKSLD---------------------ETLQKSRNLMRIGLSFNKIEFLTKD 195
+SL+ N I L E LQ NL + LS N IE + +
Sbjct: 211 ESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVI--E 268
Query: 196 DFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFS-LQEIKGLRRLSVID 254
KL LDIA N +K + ++ L L+ + N + +S L E+KG R L +
Sbjct: 269 GLENNNKLTMLDIASNRIKKIE-NISHLTELQEFWMNDNLLESWSDLDELKGARSLETVY 327
Query: 255 LSHNQI 260
L N +
Sbjct: 328 LERNPL 333
Score = 54.8 bits (126), Expect = 8e-07
Identities = 57/233 (24%), Positives = 116/233 (49%), Gaps = 20/233 (8%)
Query: 55 EEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFI 114
EE + E EH L D + +++DA L H +G K+ L ++ + +
Sbjct: 52 EERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIG--KIE----GFEVLKKVKTLCL 105
Query: 115 NANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQ 174
N +K IEN + + ++ + N+++ + +L+ + L+ L N ++++ E +
Sbjct: 106 RQNLIKCIEN--LEELQSLRELDLYDNQIKKI-ENLEALTELEILDISFNLLRNI-EGVD 161
Query: 175 KSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
K L ++ L NKI + ++ + +L L++ N ++ + ++ +L +L L L N
Sbjct: 162 KLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIE-NIDTLTNLESLFLGKN 218
Query: 235 YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHNHI 287
+T+ LQ + L L+V+ + N+++ + G L+NLV++ EL L HN I
Sbjct: 219 KITK--LQNLDALTNLTVLSMQSNRLTKIEG-LQNLVNLR----ELYLSHNGI 264
>BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 191 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 247
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 248 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 307
Query: 376 LSFN 379
LS N
Sbjct: 308 LSGN 311
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 102 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 161
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 282 LNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 73 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 132
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 133 PNLRNLDLSYNKLQTL 148
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 207
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 208 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 267
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 268 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 126 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 183 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 242
Query: 383 TVNYDL 388
+++ L
Sbjct: 243 SISQGL 248
>BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat
transmembrane neuronal 4 protein.
Length = 518
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 191 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 247
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 248 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 307
Query: 376 LSFN 379
LS N
Sbjct: 308 LSGN 311
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 102 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 161
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 282 LNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 73 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 132
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 133 PNLRNLDLSYNKLQTL 148
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 207
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 208 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 267
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 268 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 126 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 183 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 242
Query: 383 TVNYDL 388
+++ L
Sbjct: 243 SISQGL 248
>BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 192 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 248
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 249 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 308
Query: 376 LSFN 379
LS N
Sbjct: 309 LSGN 312
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 103 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 162
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 163 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 222
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 223 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 282
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 283 LNLDSNKLTNISQETVNAWISLISITLSGN 312
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 74 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 133
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 134 PNLRNLDLSYNKLQTL 149
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 149 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 208
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 209 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 268
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 269 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 312
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 127 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 183
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 184 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 243
Query: 383 TVNYDL 388
+++ L
Sbjct: 244 SISQGL 249
>BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein.
Length = 519
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 72 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 131
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 132 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 191
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 192 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 248
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 249 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 308
Query: 376 LSFN 379
LS N
Sbjct: 309 LSGN 312
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 103 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 162
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 163 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 222
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 223 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 282
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 283 LNLDSNKLTNISQETVNAWISLISITLSGN 312
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 74 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 133
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 134 PNLRNLDLSYNKLQTL 149
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 149 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 208
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 209 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 268
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 269 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 312
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 67 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 126
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 127 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 183
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 184 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 243
Query: 383 TVNYDL 388
+++ L
Sbjct: 244 SISQGL 249
>BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/245 (29%), Positives = 121/245 (49%), Gaps = 22/245 (8%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI----EKDALPKGLKHVHLGINKL 96
+TLDL +N I + DF+ + L+ L ++ N IS+ E L + L+++ N+L
Sbjct: 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAE-LRYLDFSNNRL 554
Query: 97 NTLNG-ALRDLDDLEWIFINANN----LKSIENELP-TK-AKKMQLIHAAHNELQSLPSD 149
+ L+ A +L LE + I++N+ + I + L TK K +Q + N++ S S
Sbjct: 555 DLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSR 614
Query: 150 LKLMPSLQSLYFYGNNIKSL-----DETLQKSRNLMRI---GLSFNKIEFLTKDDFTEAE 201
SL++L F GN++ L + LQ +NL+++ +S N + FL F
Sbjct: 615 TMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMP 674
Query: 202 -KLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L +A N LK + L+ LK+L L+L+HN +T + R L + L +NQ
Sbjct: 675 PNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ 734
Query: 260 ISLLT 264
I LT
Sbjct: 735 IRSLT 739
Score = 55.6 bits (128), Expect = 4e-07
Identities = 68/262 (25%), Positives = 118/262 (45%), Gaps = 27/262 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKT-LDLCRNKITKLTEEDFRDIQE 63
+++ F L + SL DN++ +P LP T L L N I K+ E+DF ++ +
Sbjct: 195 IEKDAFLNLTKLKVLSLKDNNVTAVPTV----LPSTLTELYLYNNMIAKIQEDDFNNLNQ 250
Query: 64 LEHLLVADN--QISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L+ L ++ N + P K + + +N + L +L+ + +++N+L+
Sbjct: 251 LQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALT-------ELKVLRLHSNSLQ 303
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ K+Q + + N L D K + L SL S + LQ R M
Sbjct: 304 HVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLD---LSFNFELQVYRASM 360
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEF 239
+ +F+ ++ L + L + ELK N S L +L++L L+L N++
Sbjct: 361 NLSQAFSSLKSL--------KILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query: 240 SLQEIKGLRRLSVIDLSHNQIS 261
+L K +RL VIDLS N+IS
Sbjct: 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 45.6 bits (103), Expect = 5e-04
Identities = 65/254 (25%), Positives = 118/254 (46%), Gaps = 27/254 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE-----DF- 58
L S F L + Y ++N L L + L ++ LD+ N +E +F
Sbjct: 533 LNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFT 592
Query: 59 RDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTL-----NGAL---RDLDDL 109
++++ L+ L++ DN IS + + L+ + N L+ L N L ++L L
Sbjct: 593 KNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKL 652
Query: 110 EWIFINANNLK----SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGN 164
E + I+ N+L + + +P K + L A N L+S L+ + +L++L N
Sbjct: 653 EELDISKNSLSFLPSGVFDGMPPNLKNLSL---AKNGLKSFSWKKLQCLKNLETLDLSHN 709
Query: 165 NIKSLDETLQK-SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--- 220
+ ++ E L SR+L + L N+I LTK +A +L LD++ N+++ + +
Sbjct: 710 QLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPE 769
Query: 221 RSLKSLRYLNLTHN 234
L +L+ L L HN
Sbjct: 770 NVLNNLKMLLLHHN 783
Score = 36.7 bits (81), Expect = 0.22
Identities = 63/266 (23%), Positives = 115/266 (43%), Gaps = 21/266 (7%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRN-------KITKLTEED-FRDIQELEHLLVAD 71
SL N++ + + L L +++ L L +N ++ E+D F ++ +L+ L + D
Sbjct: 154 SLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKD 213
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELP-TK 129
N ++ + LP L ++L N + + +L+ L+ + ++ N + P
Sbjct: 214 NNVTAVPT-VLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAP 272
Query: 130 AKKMQLIHAAHNELQSLPSDLKLMP----SLQSLY-FYGNNIKSLDETLQKSRNLMRIGL 184
K + N +L ++LK++ SLQ + + NI L E L S+N + +
Sbjct: 273 CKNNSPLQIPVNAFDAL-TELKVLRLHSNSLQHVPPRWFKNINKLQE-LDLSQNFLAKEI 330
Query: 185 SFNK-IEFLTKDDFTEAEKLAELDI--AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
K + FL + EL + A L SL+SLK LR + F+L
Sbjct: 331 GDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNL 390
Query: 242 QEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+ L V+DL N I + S+
Sbjct: 391 SPLHNLQNLEVLDLGTNFIKIANLSM 416
Score = 34.3 bits (75), Expect = 1.2
Identities = 60/283 (21%), Positives = 105/283 (37%), Gaps = 22/283 (7%)
Query: 148 SDLKLMPSLQSLYFYGNNIKSL--DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
SD + + L+ L GN I Q L + S N+++ L F E KL
Sbjct: 511 SDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEV 570
Query: 206 LDIAYNE-------LKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
LDI+ N + ++ ++LK L+ L + N ++ + + ++ L ++ N
Sbjct: 571 LDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMES-ESLRTLEFRGN 629
Query: 259 QISLLTGSLEN----LVDVETRVLELRLDHNHIFXXXXXXXXXX--XXXXXXXXXXXIQK 312
+ +L +N L ++ EL + N + ++
Sbjct: 630 HLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKS 689
Query: 313 IXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDF-HGLPSL 371
+S+N +TT+ E SL+ LI +N I L K F L
Sbjct: 690 FSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQL 749
Query: 372 CSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLC 414
DLS NKI ++ K+ N + ++ + L N LC
Sbjct: 750 RYLDLSSNKI-----QMIQKTSFPENVLNNLKMLLLHHNRFLC 787
Score = 32.3 bits (70), Expect = 4.7
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 66 HLLV--ADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI 122
H++V D ++EI +P ++ L IN + ++ A LD L I N +
Sbjct: 46 HVIVDCTDKHLTEIP-GGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP-- 102
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
+P +K I LQ P + L+SLY GN + + + L S L +
Sbjct: 103 ---IPLGSKNNMCI----KRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPS--LQLL 153
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAY 210
L N I + K++ TE LA ++I Y
Sbjct: 154 SLEANNIFSIRKENLTE---LANIEILY 178
>AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein.
Length = 590
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 191 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 247
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 248 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 307
Query: 376 LSFN 379
LS N
Sbjct: 308 LSGN 311
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 102 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 161
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 282 LNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 73 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 132
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 133 PNLRNLDLSYNKLQTL 148
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 207
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 208 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 267
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 268 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 126 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 183 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 242
Query: 383 TVNYDL 388
+++ L
Sbjct: 243 SISQGL 248
>AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein.
Length = 1049
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/245 (29%), Positives = 121/245 (49%), Gaps = 22/245 (8%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI----EKDALPKGLKHVHLGINKL 96
+TLDL +N I + DF+ + L+ L ++ N IS+ E L + L+++ N+L
Sbjct: 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAE-LRYLDFSNNRL 554
Query: 97 NTLNG-ALRDLDDLEWIFINANN----LKSIENELP-TK-AKKMQLIHAAHNELQSLPSD 149
+ L+ A +L LE + I++N+ + I + L TK K +Q + N++ S S
Sbjct: 555 DLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSR 614
Query: 150 LKLMPSLQSLYFYGNNIKSL-----DETLQKSRNLMRI---GLSFNKIEFLTKDDFTEAE 201
SL++L F GN++ L + LQ +NL+++ +S N + FL F
Sbjct: 615 TMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMP 674
Query: 202 -KLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L +A N LK + L+ LK+L L+L+HN +T + R L + L +NQ
Sbjct: 675 PNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ 734
Query: 260 ISLLT 264
I LT
Sbjct: 735 IRSLT 739
Score = 55.6 bits (128), Expect = 4e-07
Identities = 68/262 (25%), Positives = 118/262 (45%), Gaps = 27/262 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKT-LDLCRNKITKLTEEDFRDIQE 63
+++ F L + SL DN++ +P LP T L L N I K+ E+DF ++ +
Sbjct: 195 IEKDAFLNLTKLKVLSLKDNNVTAVPTV----LPSTLTELYLYNNMIAKIQEDDFNNLNQ 250
Query: 64 LEHLLVADN--QISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L+ L ++ N + P K + + +N + L +L+ + +++N+L+
Sbjct: 251 LQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALT-------ELKVLRLHSNSLQ 303
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ K+Q + + N L D K + L SL S + LQ R M
Sbjct: 304 HVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLD---LSFNFELQVYRASM 360
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEF 239
+ +F+ ++ L + L + ELK N S L +L++L L+L N++
Sbjct: 361 NLSQAFSSLKSL--------KILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query: 240 SLQEIKGLRRLSVIDLSHNQIS 261
+L K +RL VIDLS N+IS
Sbjct: 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 45.6 bits (103), Expect = 5e-04
Identities = 65/254 (25%), Positives = 118/254 (46%), Gaps = 27/254 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE-----DF- 58
L S F L + Y ++N L L + L ++ LD+ N +E +F
Sbjct: 533 LNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFT 592
Query: 59 RDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTL-----NGAL---RDLDDL 109
++++ L+ L++ DN IS + + L+ + N L+ L N L ++L L
Sbjct: 593 KNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKL 652
Query: 110 EWIFINANNLK----SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGN 164
E + I+ N+L + + +P K + L A N L+S L+ + +L++L N
Sbjct: 653 EELDISKNSLSFLPSGVFDGMPPNLKNLSL---AKNGLKSFSWKKLQCLKNLETLDLSHN 709
Query: 165 NIKSLDETLQK-SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--- 220
+ ++ E L SR+L + L N+I LTK +A +L LD++ N+++ + +
Sbjct: 710 QLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPE 769
Query: 221 RSLKSLRYLNLTHN 234
L +L+ L L HN
Sbjct: 770 NVLNNLKMLLLHHN 783
Score = 36.7 bits (81), Expect = 0.22
Identities = 63/266 (23%), Positives = 115/266 (43%), Gaps = 21/266 (7%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRN-------KITKLTEED-FRDIQELEHLLVAD 71
SL N++ + + L L +++ L L +N ++ E+D F ++ +L+ L + D
Sbjct: 154 SLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKD 213
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELP-TK 129
N ++ + LP L ++L N + + +L+ L+ + ++ N + P
Sbjct: 214 NNVTAVPT-VLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAP 272
Query: 130 AKKMQLIHAAHNELQSLPSDLKLMP----SLQSLY-FYGNNIKSLDETLQKSRNLMRIGL 184
K + N +L ++LK++ SLQ + + NI L E L S+N + +
Sbjct: 273 CKNNSPLQIPVNAFDAL-TELKVLRLHSNSLQHVPPRWFKNINKLQE-LDLSQNFLAKEI 330
Query: 185 SFNK-IEFLTKDDFTEAEKLAELDI--AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
K + FL + EL + A L SL+SLK LR + F+L
Sbjct: 331 GDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNL 390
Query: 242 QEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+ L V+DL N I + S+
Sbjct: 391 SPLHNLQNLEVLDLGTNFIKIANLSM 416
Score = 34.3 bits (75), Expect = 1.2
Identities = 60/283 (21%), Positives = 105/283 (37%), Gaps = 22/283 (7%)
Query: 148 SDLKLMPSLQSLYFYGNNIKSL--DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
SD + + L+ L GN I Q L + S N+++ L F E KL
Sbjct: 511 SDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEV 570
Query: 206 LDIAYNE-------LKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
LDI+ N + ++ ++LK L+ L + N ++ + + ++ L ++ N
Sbjct: 571 LDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMES-ESLRTLEFRGN 629
Query: 259 QISLLTGSLEN----LVDVETRVLELRLDHNHIFXXXXXXXXXX--XXXXXXXXXXXIQK 312
+ +L +N L ++ EL + N + ++
Sbjct: 630 HLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKS 689
Query: 313 IXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDF-HGLPSL 371
+S+N +TT+ E SL+ LI +N I L K F L
Sbjct: 690 FSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQL 749
Query: 372 CSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLC 414
DLS NKI ++ K+ N + ++ + L N LC
Sbjct: 750 RYLDLSSNKI-----QMIQKTSFPENVLNNLKMLLLHHNRFLC 787
Score = 32.3 bits (70), Expect = 4.7
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 66 HLLV--ADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI 122
H++V D ++EI +P ++ L IN + ++ A LD L I N +
Sbjct: 46 HVIVDCTDKHLTEIP-GGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP-- 102
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
+P +K I LQ P + L+SLY GN + + + L S L +
Sbjct: 103 ---IPLGSKNNMCI----KRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPS--LQLL 153
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAY 210
L N I + K++ TE LA ++I Y
Sbjct: 154 SLEANNIFSIRKENLTE---LANIEILY 178
>AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat
transmembrane neuronal 4 protein protein.
Length = 518
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 191 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 247
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 248 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 307
Query: 376 LSFN 379
LS N
Sbjct: 308 LSGN 311
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 102 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 161
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 282 LNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 73 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 132
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 133 PNLRNLDLSYNKLQTL 148
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 207
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 208 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 267
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 268 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 126 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 183 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 242
Query: 383 TVNYDL 388
+++ L
Sbjct: 243 SISQGL 248
>AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ45014 fis, clone BRAWH3014609. ).
Length = 518
Score = 63.3 bits (147), Expect = 2e-09
Identities = 64/244 (26%), Positives = 101/244 (41%), Gaps = 8/244 (3%)
Query: 141 NELQSLPSD-LKLMPSLQSLYFYGNNIKSLDE-TLQKSRNLMRIGLSFNKIEFLTKDDFT 198
N +Q L S+ + L LY N I S+DE Q R L + LS NKI +L F
Sbjct: 71 NSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFH 130
Query: 199 EAEKLAELDIAYNELKYLNG-SLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSH 257
L LD++YN+L+ L + L+ L L+L N + ++ + R L +DL +
Sbjct: 131 PVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGY 190
Query: 258 NQISLLTGSLENLVDVETRVLELRLDHNHIFXXXXXXX-XXXXXXXXXXXXXXIQKIXXX 316
N++ L+ N ++ EL L+HN I+ I
Sbjct: 191 NRLRSLS---RNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQG 247
Query: 317 XXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKD-FHGLPSLCSAD 375
+S N I +E + LP+L++L N +T + ++ + SL S
Sbjct: 248 LTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISIT 307
Query: 376 LSFN 379
LS N
Sbjct: 308 LSGN 311
Score = 55.2 bits (127), Expect = 6e-07
Identities = 46/210 (21%), Positives = 93/210 (44%), Gaps = 5/210 (2%)
Query: 7 ESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEH 66
E F + + L+ N + L +P+++ LDL NK+ L E F+ +++L
Sbjct: 102 EDAFQGIRRLKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLII 161
Query: 67 LLVADNQISEIEKDALP--KGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIE 123
L + N + + + L + LG N+L +L+ A L L+ + + N I
Sbjct: 162 LHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKIN 221
Query: 124 NELPTKAKKMQLIHAAHNELQSLPSDLK-LMPSLQSLYFYGNNIKSLDE-TLQKSRNLMR 181
+ ++ I+ N ++S+ L SL +L GN+I+ ++ T + NL +
Sbjct: 222 FAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLPNLQK 281
Query: 182 IGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
+ L NK+ ++++ L + ++ N
Sbjct: 282 LNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 46.0 bits (104), Expect = 4e-04
Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 1/76 (1%)
Query: 310 IQKIXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVL-DKDFHGL 368
IQK+ + +N+I++++E + + L+ELI N IT L +K FH +
Sbjct: 73 IQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPV 132
Query: 369 PSLCSADLSFNKIHTV 384
P+L + DLS+NK+ T+
Sbjct: 133 PNLRNLDLSYNKLQTL 148
Score = 46.0 bits (104), Expect = 4e-04
Identities = 39/164 (23%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L+ F L + L NSL +P V Q ++ LDL N++ L+ F + +L
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKL 207
Query: 65 EHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKS 121
+ L + NQ S+I P+ L+ ++L N++ +++ G L + ++ N+++
Sbjct: 208 KELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQG 267
Query: 122 IENELPTKAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGN 164
IE +Q ++ N+L ++ + + SL S+ GN
Sbjct: 268 IEPGTFKCLPNLQKLNLDSNKLTNISQETVNAWISLISITLSGN 311
Score = 39.5 bits (88), Expect = 0.031
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 6/186 (3%)
Query: 206 LDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLT 264
L + +N ++ L + L L +L L HNY++ +G+RRL + LS N+I+ L
Sbjct: 66 LSLRFNSIQKLKSNQFAGLNQLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKITYLH 125
Query: 265 GSLENLVDVETRVLELRLDHNHI-FXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXX 323
+ V + L L +N + ++ +
Sbjct: 126 NKTFHPV---PNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182
Query: 324 XXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLD-KDFHGLPSLCSADLSFNKIH 382
+ YN + +L + L L+EL HN + ++ F L +L S L +N+I
Sbjct: 183 LDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR 242
Query: 383 TVNYDL 388
+++ L
Sbjct: 243 SISQGL 248
>AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 63.3 bits (147), Expect = 2e-09
Identities = 73/245 (29%), Positives = 121/245 (49%), Gaps = 22/245 (8%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI----EKDALPKGLKHVHLGINKL 96
+TLDL +N I + DF+ + L+ L ++ N IS+ E L + L+++ N+L
Sbjct: 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAE-LRYLDFSNNRL 554
Query: 97 NTLNG-ALRDLDDLEWIFINANN----LKSIENELP-TK-AKKMQLIHAAHNELQSLPSD 149
+ L+ A +L LE + I++N+ + I + L TK K +Q + N++ S S
Sbjct: 555 DLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSR 614
Query: 150 LKLMPSLQSLYFYGNNIKSL-----DETLQKSRNLMRI---GLSFNKIEFLTKDDFTEAE 201
SL++L F GN++ L + LQ +NL+++ +S N + FL F
Sbjct: 615 TMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMP 674
Query: 202 -KLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQ 259
L L +A N LK + L+ LK+L L+L+HN +T + R L + L +NQ
Sbjct: 675 PNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ 734
Query: 260 ISLLT 264
I LT
Sbjct: 735 IRSLT 739
Score = 55.6 bits (128), Expect = 4e-07
Identities = 68/262 (25%), Positives = 118/262 (45%), Gaps = 27/262 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKT-LDLCRNKITKLTEEDFRDIQE 63
+++ F L + SL DN++ +P LP T L L N I K+ E+DF ++ +
Sbjct: 195 IEKDAFLNLTKLKVLSLKDNNVTAVPTV----LPSTLTELYLYNNMIAKIQEDDFNNLNQ 250
Query: 64 LEHLLVADN--QISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L+ L ++ N + P K + + +N + L +L+ + +++N+L+
Sbjct: 251 LQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALT-------ELKVLRLHSNSLQ 303
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ K+Q + + N L D K + L SL S + LQ R M
Sbjct: 304 HVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLD---LSFNFELQVYRASM 360
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEF 239
+ +F+ ++ L + L + ELK N S L +L++L L+L N++
Sbjct: 361 NLSQAFSSLKSL--------KILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query: 240 SLQEIKGLRRLSVIDLSHNQIS 261
+L K +RL VIDLS N+IS
Sbjct: 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 45.6 bits (103), Expect = 5e-04
Identities = 65/254 (25%), Positives = 118/254 (46%), Gaps = 27/254 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE-----DF- 58
L S F L + Y ++N L L + L ++ LD+ N +E +F
Sbjct: 533 LNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFT 592
Query: 59 RDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTL-----NGAL---RDLDDL 109
++++ L+ L++ DN IS + + L+ + N L+ L N L ++L L
Sbjct: 593 KNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKL 652
Query: 110 EWIFINANNLK----SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGN 164
E + I+ N+L + + +P K + L A N L+S L+ + +L++L N
Sbjct: 653 EELDISKNSLSFLPSGVFDGMPPNLKNLSL---AKNGLKSFSWKKLQCLKNLETLDLSHN 709
Query: 165 NIKSLDETLQK-SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--- 220
+ ++ E L SR+L + L N+I LTK +A +L LD++ N+++ + +
Sbjct: 710 QLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPE 769
Query: 221 RSLKSLRYLNLTHN 234
L +L+ L L HN
Sbjct: 770 NVLNNLKMLLLHHN 783
Score = 36.7 bits (81), Expect = 0.22
Identities = 63/266 (23%), Positives = 115/266 (43%), Gaps = 21/266 (7%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRN-------KITKLTEED-FRDIQELEHLLVAD 71
SL N++ + + L L +++ L L +N ++ E+D F ++ +L+ L + D
Sbjct: 154 SLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKD 213
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELP-TK 129
N ++ + LP L ++L N + + +L+ L+ + ++ N + P
Sbjct: 214 NNVTAVPT-VLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAP 272
Query: 130 AKKMQLIHAAHNELQSLPSDLKLMP----SLQSLY-FYGNNIKSLDETLQKSRNLMRIGL 184
K + N +L ++LK++ SLQ + + NI L E L S+N + +
Sbjct: 273 CKNNSPLQIPVNAFDAL-TELKVLRLHSNSLQHVPPRWFKNINKLQE-LDLSQNFLAKEI 330
Query: 185 SFNK-IEFLTKDDFTEAEKLAELDI--AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
K + FL + EL + A L SL+SLK LR + F+L
Sbjct: 331 GDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNL 390
Query: 242 QEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+ L V+DL N I + S+
Sbjct: 391 SPLHNLQNLEVLDLGTNFIKIANLSM 416
Score = 34.3 bits (75), Expect = 1.2
Identities = 60/283 (21%), Positives = 105/283 (37%), Gaps = 22/283 (7%)
Query: 148 SDLKLMPSLQSLYFYGNNIKSL--DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAE 205
SD + + L+ L GN I Q L + S N+++ L F E KL
Sbjct: 511 SDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEV 570
Query: 206 LDIAYNE-------LKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHN 258
LDI+ N + ++ ++LK L+ L + N ++ + + ++ L ++ N
Sbjct: 571 LDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMES-ESLRTLEFRGN 629
Query: 259 QISLLTGSLEN----LVDVETRVLELRLDHNHIFXXXXXXXXXX--XXXXXXXXXXXIQK 312
+ +L +N L ++ EL + N + ++
Sbjct: 630 HLDVLWREGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKS 689
Query: 313 IXXXXXXXXXXXXXXXVSYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDF-HGLPSL 371
+S+N +TT+ E SL+ LI +N I L K F L
Sbjct: 690 FSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQL 749
Query: 372 CSADLSFNKIHTVNYDLVSKSRCTINGVPSILKIYLQDNPVLC 414
DLS NKI ++ K+ N + ++ + L N LC
Sbjct: 750 RYLDLSSNKI-----QMIQKTSFPENVLNNLKMLLLHHNRFLC 787
Score = 32.3 bits (70), Expect = 4.7
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 66 HLLV--ADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI 122
H++V D ++EI +P ++ L IN + ++ A LD L I N +
Sbjct: 46 HVIVDCTDKHLTEIP-GGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP-- 102
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
+P +K I LQ P + L+SLY GN + + + L S L +
Sbjct: 103 ---IPLGSKNNMCI----KRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPS--LQLL 153
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAY 210
L N I + K++ TE LA ++I Y
Sbjct: 154 SLEANNIFSIRKENLTE---LANIEILY 178
>AY899851-1|AAX85199.1| 730|Homo sapiens LGR8.1 protein.
Length = 730
Score = 62.9 bits (146), Expect = 3e-09
Identities = 58/227 (25%), Positives = 101/227 (44%), Gaps = 28/227 (12%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKL 96
+V L L +NKI L ++ F +L+ + + N I I + A L+ ++L N +
Sbjct: 138 NVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCI 197
Query: 97 NTLN-GALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL-KLMP 154
TL G +DL L W+ ++ N + I L T + + +N L++LP + MP
Sbjct: 198 TTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQMCAQMP 257
Query: 155 SLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELK 214
L + L N+I++LT F + L LD++ N +
Sbjct: 258 QLNW-----------------------VDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTIT 294
Query: 215 YLNGSL-RSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L+ L + LK L+ LNL+ N + + + L++L +DL +I
Sbjct: 295 ELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEI 341
Score = 50.8 bits (116), Expect = 1e-05
Identities = 58/237 (24%), Positives = 103/237 (43%), Gaps = 27/237 (11%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQEL 64
L + VF K + L N + + R L +++ L L N IT L F+D+ +L
Sbjct: 152 LPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQL 211
Query: 65 EHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIEN 124
L++ DN I+ I + + G+N L L+ +N N L+++
Sbjct: 212 TWLILDDNPITRIS--------QRLFTGLNSLFFLS------------MVN-NYLEALPK 250
Query: 125 ELPTKAKKMQLIHAAHNELQSLPSDLKL-MPSLQSLYFYGNNIKSLDETLQKSRNLM-RI 182
++ + ++ + N ++ L + L SL L N I L L K L+ ++
Sbjct: 251 QMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLDLSSNTITELSPHLFKDLKLLQKL 310
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF 239
LS N + +L K+ F ++L LD+ E+ +N R + ++ NL+H Y F
Sbjct: 311 NLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNIN--TRMFQPMK--NLSHIYFKNF 363
Score = 41.9 bits (94), Expect = 0.006
Identities = 35/144 (24%), Positives = 67/144 (46%), Gaps = 3/144 (2%)
Query: 126 LPTKAKKMQLIHAAHNELQSLPSDLKLM-PSLQSLYFYGNNIKSLD-ETLQKSRNLMRIG 183
+P + + L+ N++ SLP + + L+ ++ N I+ + + NL +
Sbjct: 132 VPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILY 191
Query: 184 LSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL-RSLKSLRYLNLTHNYMTEFSLQ 242
L+ N I L F + +L L + N + ++ L L SL +L++ +NY+ Q
Sbjct: 192 LNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALPKQ 251
Query: 243 EIKGLRRLSVIDLSHNQISLLTGS 266
+ +L+ +DL N+I LT S
Sbjct: 252 MCAQMPQLNWVDLEGNRIKYLTNS 275
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 62.5 bits (145), Expect = 4e-09
Identities = 84/350 (24%), Positives = 145/350 (41%), Gaps = 21/350 (6%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLN 97
++ L L R + L EE +Q+LEHL V+ N ++ + E +LP L+ + N L
Sbjct: 35 LRWLKLNRTGLCYLPEE-LAALQKLEHLSVSHNNLTTLHGELSSLPS-LRAIVARANSLK 92
Query: 98 TLNGALRD---LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-M 153
+G D LDDL + ++ N L EL AK M +++ +HN + ++P+ L + +
Sbjct: 93 N-SGVPDDIFKLDDLSVLDLSHNQLTECPRELEN-AKNMLVLNLSHNSIDTIPNQLFINL 150
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L L N ++SL +++ +L + L+ N + L L + +
Sbjct: 151 TDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQR 210
Query: 214 KYLN--GSLRSLKSLRYLNLTHNYMTEFS--LQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N SL L +L ++L+ N +T L + LRRL+ LS NQI+ L+ ++
Sbjct: 211 TQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLN---LSSNQITELSLCIDQ 267
Query: 270 LVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
V VET L L N + + +
Sbjct: 268 WVHVET----LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFM 323
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFN 379
+ N+ L S P L +L+ + N++ L + H L + D+ N
Sbjct: 324 AANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 10/239 (4%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI--SEIEKDALP-KGLKHVH 90
LQ L H L + N +T L E + L ++ N + S + D L +
Sbjct: 55 LQKLEH---LSVSHNNLTTLHGE-LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLD 110
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL 150
L N+L L + ++ + ++ N++ +I N+L + + + N L+SLP +
Sbjct: 111 LSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQM 170
Query: 151 KLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGL-SFNKIEFLTKDDFTEAEKLAELDI 208
+ + LQ+L GN + L L + L S + + LA++D+
Sbjct: 171 RRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDL 230
Query: 209 AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N+L + L +L SLR LNL+ N +TE SL I + ++LS NQ++ L ++
Sbjct: 231 SCNDLTRVPECLYTLPSLRRLNLSSNQITELSLC-IDQWVHVETLNLSRNQLTSLPSAI 288
Score = 59.7 bits (138), Expect = 3e-08
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 18/283 (6%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KLD + L+ N L E PR L++ ++ L+L N I + + F ++ +L +L +++
Sbjct: 102 KLDDLSVLDLSHNQLTECPRE-LENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSE 160
Query: 72 NQISEIEKDALPKGLKHVHLGINKLN---TLNGALRDLDDLEWI-FINANNLKSIENELP 127
N++ + P+ + VHL LN L+ LR L + + ++ + + ++ LP
Sbjct: 161 NRLESLP----PQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLP 216
Query: 128 TKAK---KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + + + + N+L +P L +PSL+ L N I L + + ++ + L
Sbjct: 217 TSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNL 276
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKY--LNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ L + KL +L + N+L + L + L +L +N + E +
Sbjct: 277 SRNQLTSL-PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNL-ELVPE 334
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ +L + L+ N + L ++ L ++E VL++R + N
Sbjct: 335 SLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIE--VLDVRENPN 375
Score = 58.0 bits (134), Expect = 8e-08
Identities = 63/245 (25%), Positives = 118/245 (48%), Gaps = 17/245 (6%)
Query: 37 LPHVKTLDLCRNKITK-LTEEDFRDIQELEHLLVADNQISEIEKD--ALPKGLKHVHLGI 93
LP V+ +DL N E+ + + L L + + + ++ AL K L+H+ +
Sbjct: 7 LPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQK-LEHLSVSH 65
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N L TL+G L L L I AN+LK+ + +++ K + ++ +HN+L P +L+
Sbjct: 66 NNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDI-FKLDDLSVLDLSHNQLTECPRELE 124
Query: 152 LMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD-IA 209
++ L N+I ++ ++ +L+ + LS N++E L + +L L +
Sbjct: 125 NAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLP----PQMRRLVHLQTLV 180
Query: 210 YNELKYLNGSLRSL---KSLRYLNLTHNYMTEFSL-QEIKGLRRLSVIDLSHNQISLLTG 265
N L+ LR L +L+ L+L T+ +L ++GL L+ +DLS N ++ +
Sbjct: 181 LNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPE 240
Query: 266 SLENL 270
L L
Sbjct: 241 CLYTL 245
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 62.5 bits (145), Expect = 4e-09
Identities = 84/350 (24%), Positives = 145/350 (41%), Gaps = 21/350 (6%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLN 97
++ L L R + L EE +Q+LEHL V+ N ++ + E +LP L+ + N L
Sbjct: 34 LRWLKLNRTGLCYLPEE-LAALQKLEHLSVSHNNLTTLHGELSSLPS-LRAIVARANSLK 91
Query: 98 TLNGALRD---LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-M 153
+G D LDDL + ++ N L EL AK M +++ +HN + ++P+ L + +
Sbjct: 92 N-SGVPDDIFKLDDLSVLDLSHNQLTECPRELEN-AKNMLVLNLSHNSIDTIPNQLFINL 149
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L L N ++SL +++ +L + L+ N + L L + +
Sbjct: 150 TDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQR 209
Query: 214 KYLN--GSLRSLKSLRYLNLTHNYMTEFS--LQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N SL L +L ++L+ N +T L + LRRL+ LS NQI+ L+ ++
Sbjct: 210 TQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLN---LSSNQITELSLCIDQ 266
Query: 270 LVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
V VET L L N + + +
Sbjct: 267 WVHVET----LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFM 322
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFN 379
+ N+ L S P L +L+ + N++ L + H L + D+ N
Sbjct: 323 AANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 372
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 10/239 (4%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI--SEIEKDALP-KGLKHVH 90
LQ L H L + N +T L E + L ++ N + S + D L +
Sbjct: 54 LQKLEH---LSVSHNNLTTLHGE-LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLD 109
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL 150
L N+L L + ++ + ++ N++ +I N+L + + + N L+SLP +
Sbjct: 110 LSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQM 169
Query: 151 KLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGL-SFNKIEFLTKDDFTEAEKLAELDI 208
+ + LQ+L GN + L L + L S + + LA++D+
Sbjct: 170 RRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDL 229
Query: 209 AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N+L + L +L SLR LNL+ N +TE SL I + ++LS NQ++ L ++
Sbjct: 230 SCNDLTRVPECLYTLPSLRRLNLSSNQITELSLC-IDQWVHVETLNLSRNQLTSLPSAI 287
Score = 59.7 bits (138), Expect = 3e-08
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 18/283 (6%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KLD + L+ N L E PR L++ ++ L+L N I + + F ++ +L +L +++
Sbjct: 101 KLDDLSVLDLSHNQLTECPRE-LENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSE 159
Query: 72 NQISEIEKDALPKGLKHVHLGINKLN---TLNGALRDLDDLEWI-FINANNLKSIENELP 127
N++ + P+ + VHL LN L+ LR L + + ++ + + ++ LP
Sbjct: 160 NRLESLP----PQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLP 215
Query: 128 TKAK---KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + + + + N+L +P L +PSL+ L N I L + + ++ + L
Sbjct: 216 TSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNL 275
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKY--LNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ L + KL +L + N+L + L + L +L +N + E +
Sbjct: 276 SRNQLTSL-PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNL-ELVPE 333
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ +L + L+ N + L ++ L ++E VL++R + N
Sbjct: 334 SLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIE--VLDVRENPN 374
Score = 58.0 bits (134), Expect = 8e-08
Identities = 63/245 (25%), Positives = 118/245 (48%), Gaps = 17/245 (6%)
Query: 37 LPHVKTLDLCRNKITK-LTEEDFRDIQELEHLLVADNQISEIEKD--ALPKGLKHVHLGI 93
LP V+ +DL N E+ + + L L + + + ++ AL K L+H+ +
Sbjct: 6 LPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQK-LEHLSVSH 64
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N L TL+G L L L I AN+LK+ + +++ K + ++ +HN+L P +L+
Sbjct: 65 NNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDI-FKLDDLSVLDLSHNQLTECPRELE 123
Query: 152 LMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD-IA 209
++ L N+I ++ ++ +L+ + LS N++E L + +L L +
Sbjct: 124 NAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLP----PQMRRLVHLQTLV 179
Query: 210 YNELKYLNGSLRSL---KSLRYLNLTHNYMTEFSL-QEIKGLRRLSVIDLSHNQISLLTG 265
N L+ LR L +L+ L+L T+ +L ++GL L+ +DLS N ++ +
Sbjct: 180 LNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPE 239
Query: 266 SLENL 270
L L
Sbjct: 240 CLYTL 244
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 62.5 bits (145), Expect = 4e-09
Identities = 84/350 (24%), Positives = 145/350 (41%), Gaps = 21/350 (6%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLN 97
++ L L R + L EE +Q+LEHL V+ N ++ + E +LP L+ + N L
Sbjct: 35 LRWLKLNRTGLCYLPEE-LAALQKLEHLSVSHNNLTTLHGELSSLPS-LRAIVARANSLK 92
Query: 98 TLNGALRD---LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-M 153
+G D LDDL + ++ N L EL AK M +++ +HN + ++P+ L + +
Sbjct: 93 N-SGVPDDIFKLDDLSVLDLSHNQLTECPRELEN-AKNMLVLNLSHNSIDTIPNQLFINL 150
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L L N ++SL +++ +L + L+ N + L L + +
Sbjct: 151 TDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQR 210
Query: 214 KYLN--GSLRSLKSLRYLNLTHNYMTEFS--LQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N SL L +L ++L+ N +T L + LRRL+ LS NQI+ L+ ++
Sbjct: 211 TQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLN---LSSNQITELSLCIDQ 267
Query: 270 LVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
V VET L L N + + +
Sbjct: 268 WVHVET----LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFM 323
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFN 379
+ N+ L S P L +L+ + N++ L + H L + D+ N
Sbjct: 324 AANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 373
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 10/239 (4%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI--SEIEKDALP-KGLKHVH 90
LQ L H L + N +T L E + L ++ N + S + D L +
Sbjct: 55 LQKLEH---LSVSHNNLTTLHGE-LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLD 110
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL 150
L N+L L + ++ + ++ N++ +I N+L + + + N L+SLP +
Sbjct: 111 LSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQM 170
Query: 151 KLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGL-SFNKIEFLTKDDFTEAEKLAELDI 208
+ + LQ+L GN + L L + L S + + LA++D+
Sbjct: 171 RRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDL 230
Query: 209 AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N+L + L +L SLR LNL+ N +TE SL I + ++LS NQ++ L ++
Sbjct: 231 SCNDLTRVPECLYTLPSLRRLNLSSNQITELSLC-IDQWVHVETLNLSRNQLTSLPSAI 288
Score = 59.7 bits (138), Expect = 3e-08
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 18/283 (6%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KLD + L+ N L E PR L++ ++ L+L N I + + F ++ +L +L +++
Sbjct: 102 KLDDLSVLDLSHNQLTECPRE-LENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSE 160
Query: 72 NQISEIEKDALPKGLKHVHLGINKLN---TLNGALRDLDDLEWI-FINANNLKSIENELP 127
N++ + P+ + VHL LN L+ LR L + + ++ + + ++ LP
Sbjct: 161 NRLESLP----PQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLP 216
Query: 128 TKAK---KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + + + + N+L +P L +PSL+ L N I L + + ++ + L
Sbjct: 217 TSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNL 276
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKY--LNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ L + KL +L + N+L + L + L +L +N + E +
Sbjct: 277 SRNQLTSL-PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNL-ELVPE 334
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ +L + L+ N + L ++ L ++E VL++R + N
Sbjct: 335 SLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIE--VLDVRENPN 375
Score = 58.0 bits (134), Expect = 8e-08
Identities = 63/245 (25%), Positives = 118/245 (48%), Gaps = 17/245 (6%)
Query: 37 LPHVKTLDLCRNKITK-LTEEDFRDIQELEHLLVADNQISEIEKD--ALPKGLKHVHLGI 93
LP V+ +DL N E+ + + L L + + + ++ AL K L+H+ +
Sbjct: 7 LPFVRGVDLSGNDFKGGYFPENVKAMTSLRWLKLNRTGLCYLPEELAALQK-LEHLSVSH 65
Query: 94 NKLNTLNGALRDLDDLEWIFINANNLKS--IENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N L TL+G L L L I AN+LK+ + +++ K + ++ +HN+L P +L+
Sbjct: 66 NNLTTLHGELSSLPSLRAIVARANSLKNSGVPDDI-FKLDDLSVLDLSHNQLTECPRELE 124
Query: 152 LMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD-IA 209
++ L N+I ++ ++ +L+ + LS N++E L + +L L +
Sbjct: 125 NAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLP----PQMRRLVHLQTLV 180
Query: 210 YNELKYLNGSLRSL---KSLRYLNLTHNYMTEFSL-QEIKGLRRLSVIDLSHNQISLLTG 265
N L+ LR L +L+ L+L T+ +L ++GL L+ +DLS N ++ +
Sbjct: 181 LNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPE 240
Query: 266 SLENL 270
L L
Sbjct: 241 CLYTL 245
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 62.5 bits (145), Expect = 4e-09
Identities = 46/169 (27%), Positives = 80/169 (47%), Gaps = 3/169 (1%)
Query: 114 INANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL 173
++ N + I + + K +Q+ + N L LP + +L L +++SL E +
Sbjct: 8 VSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENI 66
Query: 174 QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTH 233
NL + L N + +L D T+ +L ELD+ NE+ L S+ +L L+ L L
Sbjct: 67 GNLYNLASLELRENLLTYLP-DSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDG 125
Query: 234 NYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRL 282
N ++E QEI L+ L +D+S N++ L + L + V+ L
Sbjct: 126 NQLSELP-QEIGNLKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNL 173
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/210 (23%), Positives = 100/210 (47%), Gaps = 27/210 (12%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
+ LV+ ++ N +PE+P + ++ D N +T+L E F ++Q L L V D
Sbjct: 1 MQLVE-LDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPES-FPELQNLTCLSVND- 56
Query: 73 QISEIEKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKK 132
I +LP+ + G L +L LE + N L + + L T+ ++
Sbjct: 57 ----ISLQSLPENI--------------GNLYNLASLE---LRENLLTYLPDSL-TQLRR 94
Query: 133 MQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFL 192
++ + +NE+ +LP + + L+ L+ GN + L + + +NL+ + +S N++E L
Sbjct: 95 LEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERL 154
Query: 193 TKDDFTEAEKLAELDIAYNELKYLNGSLRS 222
++ + L +L I+ N L+ + L +
Sbjct: 155 -PEEISGLTSLTDLVISQNLLETIPDGLEN 183
Score = 47.2 bits (107), Expect = 2e-04
Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 2/127 (1%)
Query: 143 LQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEK 202
LQSLP ++ + +L SL N + L ++L + R L + L N+I L +
Sbjct: 59 LQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLP-ESIGALLH 117
Query: 203 LAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISL 262
L +L + N+L L + +LK+L L+++ N + +EI GL L+ + +S N +
Sbjct: 118 LKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLP-EEISGLTSLTDLVISQNLLET 176
Query: 263 LTGSLEN 269
+ LEN
Sbjct: 177 IPDGLEN 183
Score = 40.3 bits (90), Expect = 0.018
Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 202 KLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF--SLQEIKGLRRLSVIDLSHNQ 259
+L ELD++ NE+ + S+ K+L+ + + N +T S E++ L LSV D+S
Sbjct: 2 QLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQS 61
Query: 260 ISLLTGSLENLVDVETR 276
+ G+L NL +E R
Sbjct: 62 LPENIGNLYNLASLELR 78
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 62.5 bits (145), Expect = 4e-09
Identities = 84/350 (24%), Positives = 145/350 (41%), Gaps = 21/350 (6%)
Query: 40 VKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--EKDALPKGLKHVHLGINKLN 97
++ L L R + L EE +Q+LEHL V+ N ++ + E +LP L+ + N L
Sbjct: 22 LRWLKLNRTGLCYLPEE-LAALQKLEHLSVSHNNLTTLHGELSSLPS-LRAIVARANSLK 79
Query: 98 TLNGALRD---LDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKL-M 153
+G D LDDL + ++ N L EL AK M +++ +HN + ++P+ L + +
Sbjct: 80 N-SGVPDDIFKLDDLSVLDLSHNQLTECPRELEN-AKNMLVLNLSHNSIDTIPNQLFINL 137
Query: 154 PSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNEL 213
L L N ++SL +++ +L + L+ N + L L + +
Sbjct: 138 TDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQR 197
Query: 214 KYLN--GSLRSLKSLRYLNLTHNYMTEFS--LQEIKGLRRLSVIDLSHNQISLLTGSLEN 269
N SL L +L ++L+ N +T L + LRRL+ LS NQI+ L+ ++
Sbjct: 198 TQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLN---LSSNQITELSLCIDQ 254
Query: 270 LVDVETRVLELRLDHNHIFXXXXXXXXXXXXXXXXXXXXXIQKIXXXXXXXXXXXXXXXV 329
V VET L L N + + +
Sbjct: 255 WVHVET----LNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFM 310
Query: 330 SYNHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFN 379
+ N+ L S P L +L+ + N++ L + H L + D+ N
Sbjct: 311 AANNNLELVPESLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIEVLDVREN 360
Score = 59.7 bits (138), Expect = 3e-08
Identities = 60/239 (25%), Positives = 107/239 (44%), Gaps = 10/239 (4%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQI--SEIEKDALP-KGLKHVH 90
LQ L H L + N +T L E + L ++ N + S + D L +
Sbjct: 42 LQKLEH---LSVSHNNLTTLHGE-LSSLPSLRAIVARANSLKNSGVPDDIFKLDDLSVLD 97
Query: 91 LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDL 150
L N+L L + ++ + ++ N++ +I N+L + + + N L+SLP +
Sbjct: 98 LSHNQLTECPRELENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSENRLESLPPQM 157
Query: 151 KLMPSLQSLYFYGNNIKSLD-ETLQKSRNLMRIGL-SFNKIEFLTKDDFTEAEKLAELDI 208
+ + LQ+L GN + L L + L S + + LA++D+
Sbjct: 158 RRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLPTSLEGLSNLADVDL 217
Query: 209 AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ N+L + L +L SLR LNL+ N +TE SL I + ++LS NQ++ L ++
Sbjct: 218 SCNDLTRVPECLYTLPSLRRLNLSSNQITELSLC-IDQWVHVETLNLSRNQLTSLPSAI 275
Score = 59.7 bits (138), Expect = 3e-08
Identities = 66/283 (23%), Positives = 133/283 (46%), Gaps = 18/283 (6%)
Query: 12 KLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVAD 71
KLD + L+ N L E PR L++ ++ L+L N I + + F ++ +L +L +++
Sbjct: 89 KLDDLSVLDLSHNQLTECPRE-LENAKNMLVLNLSHNSIDTIPNQLFINLTDLLYLDLSE 147
Query: 72 NQISEIEKDALPKGLKHVHLGINKLN---TLNGALRDLDDLEWI-FINANNLKSIENELP 127
N++ + P+ + VHL LN L+ LR L + + ++ + + ++ LP
Sbjct: 148 NRLESLP----PQMRRLVHLQTLVLNGNPLLHAQLRQLPAMTALQTLHLRSTQRTQSNLP 203
Query: 128 TKAK---KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGL 184
T + + + + N+L +P L +PSL+ L N I L + + ++ + L
Sbjct: 204 TSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCIDQWVHVETLNL 263
Query: 185 SFNKIEFLTKDDFTEAEKLAELDIAYNELKY--LNGSLRSLKSLRYLNLTHNYMTEFSLQ 242
S N++ L + KL +L + N+L + L + L +L +N + E +
Sbjct: 264 SRNQLTSL-PSAICKLSKLKKLYLNSNKLDFDGLPSGIGKLTNLEEFMAANNNL-ELVPE 321
Query: 243 EIKGLRRLSVIDLSHNQISLLTGSLENLVDVETRVLELRLDHN 285
+ +L + L+ N + L ++ L ++E VL++R + N
Sbjct: 322 SLCRCPKLRKLVLNKNHLVTLPEAIHFLTEIE--VLDVRENPN 362
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 62.1 bits (144), Expect = 5e-09
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 3/176 (1%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ + NSL LP ++ Q LP++ L L N I + E + +L+ L ++DN
Sbjct: 40 LQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIV-VVPEAIGSLVKLQCLDLSDN 98
Query: 73 QISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
+ + + + L+H+ L N+L L + DL +L+ + I+ N L ++ L
Sbjct: 99 ALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERL-HMCL 157
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+Q + N L +P L +PSL L GN + L L +SR L + + N
Sbjct: 158 SLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 53.6 bits (123), Expect = 2e-06
Identities = 41/176 (23%), Positives = 89/176 (50%), Gaps = 4/176 (2%)
Query: 61 IQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANN 118
+Q LE L + N ++ + ++ K L ++L N + + A+ L L+ + ++ N
Sbjct: 40 LQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNA 99
Query: 119 LKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
L+ + E+ + + ++ + A+N+LQ LP ++ + LQ+L N + +L E L +
Sbjct: 100 LEIVCPEIG-RLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLS 158
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L + + N++ ++ + + L EL +A N L +L L + L+Y+ + +N
Sbjct: 159 LQYLTVDRNRLWYVPR-HLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 50.8 bits (116), Expect = 1e-05
Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 156 LQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELK 214
L+ LY N++ SL E L QK NL+ + L N I + + KL LD++ N L+
Sbjct: 43 LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNI-VVVPEAIGSLVKLQCLDLSDNALE 101
Query: 215 YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVE 274
+ + L++LR+L L +N + +F E+ L+ L +D+S N++ L L + ++
Sbjct: 102 IVCPEIGRLRALRHLRLANNQL-QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQ 160
Score = 36.7 bits (81), Expect = 0.22
Identities = 21/53 (39%), Positives = 27/53 (50%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTV 384
N +T+L E LP+L EL H NNI V+ + L L DLS N + V
Sbjct: 51 NSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIV 103
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 62.1 bits (144), Expect = 5e-09
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 3/176 (1%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L ++ + NSL LP ++ Q LP++ L L N I + E + +L+ L ++DN
Sbjct: 40 LQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIV-VVPEAIGSLVKLQCLDLSDN 98
Query: 73 QISEI-EKDALPKGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAK 131
+ + + + L+H+ L N+L L + DL +L+ + I+ N L ++ L
Sbjct: 99 ALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERL-HMCL 157
Query: 132 KMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+Q + N L +P L +PSL L GN + L L +SR L + + N
Sbjct: 158 SLQYLTVDRNRLWYVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 53.6 bits (123), Expect = 2e-06
Identities = 41/176 (23%), Positives = 89/176 (50%), Gaps = 4/176 (2%)
Query: 61 IQELEHLLVADNQISEIEKDALPK--GLKHVHLGINKLNTLNGALRDLDDLEWIFINANN 118
+Q LE L + N ++ + ++ K L ++L N + + A+ L L+ + ++ N
Sbjct: 40 LQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNA 99
Query: 119 LKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRN 178
L+ + E+ + + ++ + A+N+LQ LP ++ + LQ+L N + +L E L +
Sbjct: 100 LEIVCPEIG-RLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLS 158
Query: 179 LMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
L + + N++ ++ + + L EL +A N L +L L + L+Y+ + +N
Sbjct: 159 LQYLTVDRNRLWYVPR-HLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 50.8 bits (116), Expect = 1e-05
Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 156 LQSLYFYGNNIKSLDETL-QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELK 214
L+ LY N++ SL E L QK NL+ + L N I + + KL LD++ N L+
Sbjct: 43 LERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNI-VVVPEAIGSLVKLQCLDLSDNALE 101
Query: 215 YLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLENLVDVE 274
+ + L++LR+L L +N + +F E+ L+ L +D+S N++ L L + ++
Sbjct: 102 IVCPEIGRLRALRHLRLANNQL-QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQ 160
Score = 36.7 bits (81), Expect = 0.22
Identities = 21/53 (39%), Positives = 27/53 (50%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNITVLDKDFHGLPSLCSADLSFNKIHTV 384
N +T+L E LP+L EL H NNI V+ + L L DLS N + V
Sbjct: 51 NSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIV 103
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 61.7 bits (143), Expect = 7e-09
Identities = 53/187 (28%), Positives = 90/187 (48%), Gaps = 5/187 (2%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F+ L + L +N L +P L LP +++L L N I+ + E F + L HL +
Sbjct: 36 FSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWL 95
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENEL 126
DN ++EI AL L+ + L +N+++ + + A ++L L + +N N L+ +
Sbjct: 96 DDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAI 155
Query: 127 PTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETL-QKSRNLMRIGLS 185
T + +L ++Q P DLK SL+ L I+ L + Q+ L + LS
Sbjct: 156 RTLGRLQELSLNGAMDIQEFP-DLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELS 214
Query: 186 FNKIEFL 192
N+IE L
Sbjct: 215 HNQIEEL 221
Score = 51.6 bits (118), Expect = 7e-06
Identities = 58/222 (26%), Positives = 99/222 (44%), Gaps = 8/222 (3%)
Query: 48 NKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNG----AL 103
N +T+L F ++ LE L ++ N +S I A GL + + + + N L G AL
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAF-SGLYSLKILMLQNNQLGGIPAEAL 60
Query: 104 RDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFY 162
+L L+ + ++AN + + ++ + N L +P L +P+LQ++
Sbjct: 61 WELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLA 120
Query: 163 GNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLR 221
N I + D Q +L+ + L++NK++ T +L EL + L+
Sbjct: 121 LNRISHIPDYAFQNLTSLVVLDLNYNKLQEFPVAIRTLG-RLQELSLNGAMDIQEFPDLK 179
Query: 222 SLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL 263
SL L LT + + L RL V++LSHNQI L
Sbjct: 180 GTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEEL 221
Score = 51.2 bits (117), Expect = 9e-06
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 8/221 (3%)
Query: 24 NSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP 83
N+L EL + HL ++ L L N ++ + + F + L+ L++ +NQ+ I +AL
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALW 61
Query: 84 K--GLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAH 140
+ L+ + L N ++ + + L L ++++ N L I +Q + A
Sbjct: 62 ELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL 121
Query: 141 NELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI-GLSFN-KIEFLTKDDFT 198
N + +P +L SL N L E R L R+ LS N ++ D
Sbjct: 122 NRISHIPD--YAFQNLTSLVVLDLNYNKLQEFPVAIRTLGRLQELSLNGAMDIQEFPDLK 179
Query: 199 EAEKLAELDIAYNELKYL-NGSLRSLKSLRYLNLTHNYMTE 238
L L + ++ L +G + L LR L L+HN + E
Sbjct: 180 GTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEE 220
Score = 46.8 bits (106), Expect = 2e-04
Identities = 36/153 (23%), Positives = 78/153 (50%), Gaps = 15/153 (9%)
Query: 4 VLKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
++ E F L + + L DN+L E+P L +LP ++ + L N+I+ + + F Q
Sbjct: 78 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAF---QN 134
Query: 64 LEHLLVADNQISEIEKDALPKGLKHVHLGINKLNTLNGA--------LRDLDDLEWIFIN 115
L L+V D +++++ P ++ LG + +LNGA L+ LE + +
Sbjct: 135 LTSLVVLDLNYNKLQE--FPVAIR--TLGRLQELSLNGAMDIQEFPDLKGTTSLEILTLT 190
Query: 116 ANNLKSIENELPTKAKKMQLIHAAHNELQSLPS 148
++ + + + + +++++ +HN+++ LPS
Sbjct: 191 RAGIRLLPSGMCQQLPRLRVLELSHNQIEELPS 223
Score = 33.9 bits (74), Expect = 1.5
Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 156 LQSLYFYGNNIKSLD-ETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELK 214
L+ L GN++ + + +L + L N++ + + E L L + N +
Sbjct: 18 LEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLIS 77
Query: 215 YL-NGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTG-SLENLVD 272
+ S L SLR+L L N +TE ++ + L L + L+ N+IS + + +NL
Sbjct: 78 LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNL-- 135
Query: 273 VETRVLELRLDHNHI 287
T ++ L L++N +
Sbjct: 136 --TSLVVLDLNYNKL 148
>AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens
cDNA FLJ45829 fis, clone NT2RP8006452. ).
Length = 870
Score = 61.7 bits (143), Expect = 7e-09
Identities = 66/256 (25%), Positives = 125/256 (48%), Gaps = 16/256 (6%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADN 72
L+ ++ L N+L P+ + + L + LDL NK T + + + +L V+ N
Sbjct: 609 LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLK-MSCIANLDVSRN 667
Query: 73 QIS-EIEKDALPK--GLKHVHLGINKLNTLNGALRD-LDDLEWIFINANNLKSIENELPT 128
I + D K LK +L N+L+ + L D ++ LE + + N + I + P
Sbjct: 668 DIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICS--PL 725
Query: 129 KAKKMQLIHAAHNELQSLPSD-LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFN 187
+ K++++++ + N + SL + L+ P ++S N + ++ L S +++ LS N
Sbjct: 726 RLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAM-PFLPPSMTILK--LSQN 782
Query: 188 KIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--RSLKSLRYLNLTHNYMTEFSLQEIK 245
K + + L LD++ N+++YL G +SL +LR L +HN ++ L E
Sbjct: 783 KFSCI-PEAILNLPHLRSLDMSSNDIQYLPGPAHWKSL-NLRELLFSHNQISILDLSEKA 840
Query: 246 GL-RRLSVIDLSHNQI 260
L R+ + LSHN++
Sbjct: 841 YLWSRVEKLHLSHNKL 856
Score = 49.6 bits (113), Expect = 3e-05
Identities = 58/259 (22%), Positives = 117/259 (45%), Gaps = 17/259 (6%)
Query: 36 HLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKG-LKHVHLGIN 94
HL H++ L+L +N +T ++ ++ L HL + N+ + L + ++ + N
Sbjct: 608 HLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRN 667
Query: 95 KLN---TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
+ L+ ++ L+ ++ N L + L +K++ + N++ + S L+
Sbjct: 668 DIGPSVVLDPTVK-CPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPLR 726
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYN 211
L L+ L N+I SL E ++ ++ ++ FL F + L ++ N
Sbjct: 727 L-KELKILNLSKNHISSLSENFLEA--CPKVESFSARMNFLAAMPFL-PPSMTILKLSQN 782
Query: 212 ELKYLNGSLRSLKSLRYLNLTHN---YMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSLE 268
+ + ++ +L LR L+++ N Y+ + + LR L SHNQIS+L L
Sbjct: 783 KFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELL---FSHNQISIL--DLS 837
Query: 269 NLVDVETRVLELRLDHNHI 287
+ +RV +L L HN +
Sbjct: 838 EKAYLWSRVEKLHLSHNKL 856
Score = 37.5 bits (83), Expect = 0.12
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 4/86 (4%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI--- 77
L+ N +P +L +LPH+++LD+ N I L L LL + NQIS +
Sbjct: 779 LSQNKFSCIPEAIL-NLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLS 837
Query: 78 EKDALPKGLKHVHLGINKLNTLNGAL 103
EK L ++ +HL NKL + L
Sbjct: 838 EKAYLWSRVEKLHLSHNKLKEVRRLL 863
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 61.7 bits (143), Expect = 7e-09
Identities = 46/180 (25%), Positives = 85/180 (47%), Gaps = 3/180 (1%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLN 97
HV+++D + + EE +R + LE LL+ NQ+ E+ + L+ + L N++
Sbjct: 13 HVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ 72
Query: 98 TLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + + L + ++ N + I + + K +Q+ + N L LP + +L
Sbjct: 73 RLPPEIANFMQLVELDVSRNEIPEIPESI-SFCKALQVADFSGNPLTRLPESFPELQNLT 131
Query: 158 SLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLN 217
L +++SL E + NL + L N + +L D T+ +L ELD+ NE+ LN
Sbjct: 132 CLSVNDISLQSLPENIGNLYNLASLELRENLLTYL-PDSLTQLRRLEELDLGNNEIYNLN 190
Score = 58.0 bits (134), Expect = 8e-08
Identities = 42/149 (28%), Positives = 75/149 (50%), Gaps = 4/149 (2%)
Query: 131 KKMQLIHAAHNELQSLPSDL-KLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKI 189
+ ++ I H L +P ++ + SL+ L N ++ L E + L ++GLS N+I
Sbjct: 12 RHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEI 71
Query: 190 EFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRYLNLTHNYMTEF--SLQEIKGL 247
+ L + +L ELD++ NE+ + S+ K+L+ + + N +T S E++ L
Sbjct: 72 QRLPPE-IANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNL 130
Query: 248 RRLSVIDLSHNQISLLTGSLENLVDVETR 276
LSV D+S + G+L NL +E R
Sbjct: 131 TCLSVNDISLQSLPENIGNLYNLASLELR 159
Score = 52.0 bits (119), Expect = 5e-06
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Query: 109 LEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKS 168
LE + ++AN L+ + + + K++ + + NE+Q LP ++ L L N I
Sbjct: 38 LEELLLDANQLRELPEQF-FQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPE 96
Query: 169 LDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSLRSLKSLRY 228
+ E++ + L S N + L + F E + L L + L+ L ++ +L +L
Sbjct: 97 IPESISFCKALQVADFSGNPLTRLP-ESFPELQNLTCLSVNDISLQSLPENIGNLYNLAS 155
Query: 229 LNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQI 260
L L N +T + + LRRL +DL +N+I
Sbjct: 156 LELRENLLT-YLPDSLTQLRRLEELDLGNNEI 186
Score = 51.2 bits (117), Expect = 9e-06
Identities = 40/153 (26%), Positives = 73/153 (47%), Gaps = 6/153 (3%)
Query: 84 KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH--AAHN 141
+ L+ + L N+L L L L + ++ N ++ + E+ A MQL+ + N
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEI---ANFMQLVELDVSRN 92
Query: 142 ELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAE 201
E+ +P + +LQ F GN + L E+ + +NL + ++ ++ L ++
Sbjct: 93 EIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSL-PENIGNLY 151
Query: 202 KLAELDIAYNELKYLNGSLRSLKSLRYLNLTHN 234
LA L++ N L YL SL L+ L L+L +N
Sbjct: 152 NLASLELRENLLTYLPDSLTQLRRLEELDLGNN 184
>AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 61.7 bits (143), Expect = 7e-09
Identities = 71/242 (29%), Positives = 121/242 (50%), Gaps = 30/242 (12%)
Query: 41 KTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEI----EKDALPKGLKHVHLGINKL 96
+TLDL +N I + DF+ + L+ L ++ N IS+ E L + L+++ N+L
Sbjct: 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAE-LRYLDFSNNRL 554
Query: 97 NTLNG-ALRDLDDLEWIFINANN----LKSIENELP-TK-AKKMQLIHAAHNELQSLPSD 149
+ L+ A +L LE + I++N+ + I + L TK K +Q + N++ S S
Sbjct: 555 DLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSR 614
Query: 150 LKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIA 209
SL++L F GN+ LD ++ N +L F KL ELDI+
Sbjct: 615 TMESESLRTLEFRGNH---LDVLWREGDN-----------RYLQL--FKNLLKLEELDIS 658
Query: 210 YNELKYL-NGSLRSL-KSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
N L +L +G + +L+ L+L N + FS ++++ L+ L +DLSHNQ++ + L
Sbjct: 659 KNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERL 718
Query: 268 EN 269
N
Sbjct: 719 SN 720
Score = 55.6 bits (128), Expect = 4e-07
Identities = 68/262 (25%), Positives = 118/262 (45%), Gaps = 27/262 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKT-LDLCRNKITKLTEEDFRDIQE 63
+++ F L + SL DN++ +P LP T L L N I K+ E+DF ++ +
Sbjct: 195 IEKDAFLNLTKLKVLSLKDNNVTAVPTV----LPSTLTELYLYNNMIAKIQEDDFNNLNQ 250
Query: 64 LEHLLVADN--QISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLK 120
L+ L ++ N + P K + + +N + L +L+ + +++N+L+
Sbjct: 251 LQILDLSGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALT-------ELKVLRLHSNSLQ 303
Query: 121 SIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLM 180
+ K+Q + + N L D K + L SL S + LQ R M
Sbjct: 304 HVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLD---LSFNFELQVYRASM 360
Query: 181 RIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGS-LRSLKSLRYLNLTHNYMTEF 239
+ +F+ ++ L + L + ELK N S L +L++L L+L N++
Sbjct: 361 NLSQAFSSLKSL--------KILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query: 240 SLQEIKGLRRLSVIDLSHNQIS 261
+L K +RL VIDLS N+IS
Sbjct: 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 39.9 bits (89), Expect = 0.023
Identities = 63/254 (24%), Positives = 116/254 (45%), Gaps = 27/254 (10%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEE-----DF- 58
L S F L + Y ++N L L + L ++ LD+ N +E +F
Sbjct: 533 LNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHMLNFT 592
Query: 59 RDIQELEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTL-----NGAL---RDLDDL 109
++++ L+ L++ DN IS + + L+ + N L+ L N L ++L L
Sbjct: 593 KNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKL 652
Query: 110 EWIFINANNLK----SIENELPTKAKKMQLIHAAHNELQSLP-SDLKLMPSLQSLYFYGN 164
E + I+ N+L + + +P K + L A N L+S L+ + +L++L N
Sbjct: 653 EELDISKNSLSFLPSGVFDGMPPNLKNLSL---AKNGLKSFSWKKLQCLKNLETLDLSHN 709
Query: 165 NIKSLDETLQK-SRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKYLNGSL--- 220
+ ++ E L SR+ + L N+I TK +A +L LD++ N+++ + +
Sbjct: 710 QLTTVPERLSNCSRSHKNLILKNNQIRSPTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPE 769
Query: 221 RSLKSLRYLNLTHN 234
L +L+ L L HN
Sbjct: 770 NVLNNLKMLLLHHN 783
Score = 36.7 bits (81), Expect = 0.22
Identities = 63/266 (23%), Positives = 115/266 (43%), Gaps = 21/266 (7%)
Query: 20 SLADNSLPELPRHVLQHLPHVKTLDLCRN-------KITKLTEED-FRDIQELEHLLVAD 71
SL N++ + + L L +++ L L +N ++ E+D F ++ +L+ L + D
Sbjct: 154 SLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKD 213
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN-GALRDLDDLEWIFINANNLKSIENELP-TK 129
N ++ + LP L ++L N + + +L+ L+ + ++ N + P
Sbjct: 214 NNVTAVPT-VLPSTLTELYLYNNMIAKIQEDDFNNLNQLQILDLSGNCPRCYNAPFPCAP 272
Query: 130 AKKMQLIHAAHNELQSLPSDLKLMP----SLQSLY-FYGNNIKSLDETLQKSRNLMRIGL 184
K + N +L ++LK++ SLQ + + NI L E L S+N + +
Sbjct: 273 CKNNSPLQIPVNAFDAL-TELKVLRLHSNSLQHVPPRWFKNINKLQE-LDLSQNFLAKEI 330
Query: 185 SFNK-IEFLTKDDFTEAEKLAELDI--AYNELKYLNGSLRSLKSLRYLNLTHNYMTEFSL 241
K + FL + EL + A L SL+SLK LR + F+L
Sbjct: 331 GDAKFLHFLPSLIQLDLSFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNL 390
Query: 242 QEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L+ L V+DL N I + S+
Sbjct: 391 SPLHNLQNLEVLDLGTNFIKIANLSM 416
Score = 32.3 bits (70), Expect = 4.7
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 66 HLLV--ADNQISEIEKDALPKGLKHVHLGINKLNTLNGA-LRDLDDLEWIFINANNLKSI 122
H++V D ++EI +P ++ L IN + ++ A LD L I N +
Sbjct: 46 HVIVDCTDKHLTEIP-GGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCNCVP-- 102
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
+P +K I LQ P + L+SLY GN + + + L S L +
Sbjct: 103 ---IPLGSKNNMCI----KRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQGLPPS--LQLL 153
Query: 183 GLSFNKIEFLTKDDFTEAEKLAELDIAY 210
L N I + K++ TE LA ++I Y
Sbjct: 154 SLEANNIFSIRKENLTE---LANIEILY 178
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 606 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 663
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 723
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 724 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 782
Query: 183 GL 184
GL
Sbjct: 783 GL 784
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 587 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 642
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 643 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 701
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 702 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 760
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 761 LRGNRLECL 769
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 499 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 557
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 558 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 617
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 618 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 676
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 677 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 727
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 532 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 588
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 589 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 648
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 707
Query: 268 ENL 270
+NL
Sbjct: 708 QNL 710
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 342 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 399
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 400 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 459
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 460 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 518
Query: 183 GL 184
GL
Sbjct: 519 GL 520
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 323 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 378
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 379 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 437
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 438 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 496
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 497 LRGNRLECL 505
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 235 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 293
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 294 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 353
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 354 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 412
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 413 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 463
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 268 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 324
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 325 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 384
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 385 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 443
Query: 268 ENL 270
+NL
Sbjct: 444 QNL 446
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 606 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 663
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 723
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 724 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 782
Query: 183 GL 184
GL
Sbjct: 783 GL 784
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 587 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 642
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 643 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 701
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 702 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 760
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 761 LRGNRLECL 769
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 499 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 557
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 558 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 617
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 618 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 676
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 677 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 727
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 532 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 588
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 589 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 648
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 707
Query: 268 ENL 270
+NL
Sbjct: 708 QNL 710
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 606 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 663
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 723
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 724 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 782
Query: 183 GL 184
GL
Sbjct: 783 GL 784
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 587 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 642
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 643 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 701
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 702 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 760
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 761 LRGNRLECL 769
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 499 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 557
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 558 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 617
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 618 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 676
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 677 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 727
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 532 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 588
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 589 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 648
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 649 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 707
Query: 268 ENL 270
+NL
Sbjct: 708 QNL 710
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 270 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 327
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 328 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 387
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 388 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 446
Query: 183 GL 184
GL
Sbjct: 447 GL 448
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 251 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 306
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 307 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 365
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 366 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 424
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 425 LRGNRLECL 433
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 163 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 221
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 222 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 281
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 282 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 340
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 341 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 391
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 196 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 252
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 253 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 312
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 313 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 371
Query: 268 ENL 270
+NL
Sbjct: 372 QNL 374
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 61.3 bits (142), Expect = 9e-09
Identities = 50/182 (27%), Positives = 91/182 (50%), Gaps = 5/182 (2%)
Query: 5 LKESVFTKLDLVDYFSLADNSLPELPRHV-LQHLPHVKTLDLCRNKITKLTEEDFRDIQE 63
+ S+F+ +L + L DN+L + + QHL + L L N I + + ++
Sbjct: 607 IPHSIFSLHNLQE-IDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTN 664
Query: 64 LEHLLVADNQISEIEKDALP-KGLKHVHLGINKLNTLNGALRDLDDLEWIFINANNLKSI 122
LE L + N+I +I + L+++ L N L L + L +L+ + I AN ++++
Sbjct: 665 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 724
Query: 123 ENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRI 182
EL + +K++ +H +N LQSLPS + + +L + GN ++ L L + L R
Sbjct: 725 PPEL-FQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELGECPLLKRS 783
Query: 183 GL 184
GL
Sbjct: 784 GL 785
Score = 60.9 bits (141), Expect = 1e-08
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 12/189 (6%)
Query: 34 LQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVH--- 90
L+ + ++ L+L R + ++ F + L+ + + DN + IE+ +H+H
Sbjct: 588 LKKMANLTELELIRCDLERIPHSIF-SLHNLQEIDLKDNNLKTIEEII---SFQHLHRLT 643
Query: 91 ---LGINKLNTLNGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLP 147
L N + + + +L +LE +++N N ++ I +L +K++ + +HN L LP
Sbjct: 644 CLKLWYNHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQL-FYCRKLRYLDLSHNNLTFLP 702
Query: 148 SDLKLMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELD 207
+D+ L+ +LQ+L N I++L L + R L + L N ++ L E L +++
Sbjct: 703 ADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSL-PSRVGELTNLTQIE 761
Query: 208 IAYNELKYL 216
+ N L+ L
Sbjct: 762 LRGNRLECL 770
Score = 48.4 bits (110), Expect = 7e-05
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 6/232 (2%)
Query: 39 HVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKDALPKGLKHVHLGINKLNT 98
H+K D+ + + + ++ +L +N+ I+ K LK + L N L+
Sbjct: 500 HIKFTDIKEIPLWIYSLKTLEELHLTGNLSAENNRYIVIDGLRELKRLKVLRLKSN-LSK 558
Query: 99 LNGALRDLD-DLEWIFINANNLKSIENELPTKAKKMQLIHAAHNELQSLPSDLKLMPSLQ 157
L + D+ L+ + IN K I K + + +L+ +P + + +LQ
Sbjct: 559 LPQVVTDVGVHLQKLSINNEGTKLIVLNSLKKMANLTELELIRCDLERIPHSIFSLHNLQ 618
Query: 158 SLYFYGNNIKSLDETL--QKSRNLMRIGLSFNKIEFLTKDDFTEAEKLAELDIAYNELKY 215
+ NN+K+++E + Q L + L +N I ++ L L + N+++
Sbjct: 619 EIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQ-IGNLTNLERLYLNRNKIEK 677
Query: 216 LNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLLTGSL 267
+ L + LRYL+L+HN +T F +I L+ L + ++ N+I L L
Sbjct: 678 IPTQLFYCRKLRYLDLSHNNLT-FLPADIGLLQNLQNLAITANRIETLPPEL 728
Score = 47.6 bits (108), Expect = 1e-04
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 94 NKLNTLNGALRDLDDLEWIFINAN--NLKSIENELPTKAKKMQLIHAAHNELQSLPSDLK 151
N+ ++G LR+L L+ + + +N L + ++ +K+ I+ +L L S LK
Sbjct: 533 NRYIVIDG-LRELKRLKVLRLKSNLSKLPQVVTDVGVHLQKLS-INNEGTKLIVLNS-LK 589
Query: 152 LMPSLQSLYFYGNNIKSLDETLQKSRNLMRIGLSFNKIEFLTKD-DFTEAEKLAELDIAY 210
M +L L +++ + ++ NL I L N ++ + + F +L L + Y
Sbjct: 590 KMANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWY 649
Query: 211 NELKYLNGSLRSLKSLRYLNLTHNYMTEFSLQEIKGLRRLSVIDLSHNQISLL---TGSL 267
N + Y+ + +L +L L L N + + Q + R+L +DLSHN ++ L G L
Sbjct: 650 NHIAYIPIQIGNLTNLERLYLNRNKIEKIPTQ-LFYCRKLRYLDLSHNNLTFLPADIGLL 708
Query: 268 ENL 270
+NL
Sbjct: 709 QNL 711
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/267 (20%), Positives = 131/267 (49%), Gaps = 9/267 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L NS+ + + L +L ++ LDL +N + + DF + +L L + +NQ++ +E
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ L+ ++L N+L + A L +L + +N+N L++I++ ++++
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 138 AAHNELQS-LPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKD 195
N++ + L + + + +L+SL G N++ + D L+ ++L + N++ + +
Sbjct: 196 IGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRR 255
Query: 196 DFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTH-NYMTEFSLQEIKGLRRLSVI 253
+ L LD+ N L+ + G ++ L+ L L + + + L L+ +
Sbjct: 256 ALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKL 315
Query: 254 DLSHN-QISLL-TGSLENLVDVETRVL 278
D+++N ++S + + +L +ET +L
Sbjct: 316 DITNNPRLSFIHPRAFHHLPQMETLML 342
Score = 44.0 bits (99), Expect = 0.001
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL-LVAD 71
L ++ S DN L +PR L+ +P +K LDL +N + ++ DF ++ L+ L L
Sbjct: 236 LQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNM 295
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN----GALRDLDDLEWIFINANNLKSIENELP 127
++ I+K AL + L I L+ A L +E + +N N L ++ +
Sbjct: 296 EELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTA 355
Query: 128 TKAKKMQLIHAAHNELQ 144
+Q + N ++
Sbjct: 356 ESLPNLQEVGLHGNPIR 372
Score = 43.6 bits (98), Expect = 0.002
Identities = 41/187 (21%), Positives = 83/187 (44%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + N + + + L ++++L L + ++++ +Q LE L
Sbjct: 185 FEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSF 244
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFI-NANNLKSIENE 125
DNQ++ + + AL + GLK + L N L + G ++ L+ + + N L SI+
Sbjct: 245 YDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKF 304
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ + +N S P +P +++L N + +L +T + NL +
Sbjct: 305 ALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTAESLPNLQEV 364
Query: 183 GLSFNKI 189
GL N I
Sbjct: 365 GLHGNPI 371
Score = 33.5 bits (73), Expect = 2.0
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N +T LE+ S L SL+EL +HN + + + F GL +L L+ N + ++
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAID 181
Score = 31.5 bits (68), Expect = 8.2
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADLSFNKI 381
N I ++++ +L +L EL N+ + D DFH LP L S L N++
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQL 129
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 60.5 bits (140), Expect = 2e-08
Identities = 56/267 (20%), Positives = 131/267 (49%), Gaps = 9/267 (3%)
Query: 21 LADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLVADNQISEIEKD 80
L NS+ + + L +L ++ LDL +N + + DF + +L L + +NQ++ +E
Sbjct: 76 LQSNSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRLEDH 135
Query: 81 ALP--KGLKHVHLGINKLNTL-NGALRDLDDLEWIFINANNLKSIENELPTKAKKMQLIH 137
+ L+ ++L N+L + A L +L + +N+N L++I++ ++++
Sbjct: 136 SFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILM 195
Query: 138 AAHNELQS-LPSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRIGLSFNKIEFLTKD 195
N++ + L + + + +L+SL G N++ + D L+ ++L + N++ + +
Sbjct: 196 IGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSFYDNQLARVPRR 255
Query: 196 DFTEAEKLAELDIAYNELKYLN-GSLRSLKSLRYLNLTH-NYMTEFSLQEIKGLRRLSVI 253
+ L LD+ N L+ + G ++ L+ L L + + + L L+ +
Sbjct: 256 ALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKFALVNLPELTKL 315
Query: 254 DLSHN-QISLL-TGSLENLVDVETRVL 278
D+++N ++S + + +L +ET +L
Sbjct: 316 DITNNPRLSFIHPRAFHHLPQMETLML 342
Score = 44.0 bits (99), Expect = 0.001
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 5/137 (3%)
Query: 13 LDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHL-LVAD 71
L ++ S DN L +PR L+ +P +K LDL +N + ++ DF ++ L+ L L
Sbjct: 236 LQSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNM 295
Query: 72 NQISEIEKDALPKGLKHVHLGINKLNTLN----GALRDLDDLEWIFINANNLKSIENELP 127
++ I+K AL + L I L+ A L +E + +N N L ++ +
Sbjct: 296 EELVSIDKFALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTA 355
Query: 128 TKAKKMQLIHAAHNELQ 144
+Q + N ++
Sbjct: 356 ESLPNLQEVGLHGNPIR 372
Score = 43.6 bits (98), Expect = 0.002
Identities = 41/187 (21%), Positives = 83/187 (44%), Gaps = 7/187 (3%)
Query: 10 FTKLDLVDYFSLADNSLPELPRHVLQHLPHVKTLDLCRNKITKLTEEDFRDIQELEHLLV 69
F L ++ + N + + + L ++++L L + ++++ +Q LE L
Sbjct: 185 FEMLPNLEILMIGGNKVDAILDMNFRPLANLRSLVLAGMNLREISDYALEGLQSLESLSF 244
Query: 70 ADNQISEIEKDALPK--GLKHVHLGINKLNTLN-GALRDLDDLEWIFI-NANNLKSIENE 125
DNQ++ + + AL + GLK + L N L + G ++ L+ + + N L SI+
Sbjct: 245 YDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGLNNMEELVSIDKF 304
Query: 126 LPTKAKKMQLIHAAHNELQSL--PSDLKLMPSLQSLYFYGNNIKSL-DETLQKSRNLMRI 182
++ + +N S P +P +++L N + +L +T + NL +
Sbjct: 305 ALVNLPELTKLDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALHQQTAESLPNLQEV 364
Query: 183 GLSFNKI 189
GL N I
Sbjct: 365 GLHGNPI 371
Score = 33.5 bits (73), Expect = 2.0
Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 1/55 (1%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNI-TVLDKDFHGLPSLCSADLSFNKIHTVN 385
N +T LE+ S L SL+EL +HN + + + F GL +L L+ N + ++
Sbjct: 127 NQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAID 181
Score = 31.5 bits (68), Expect = 8.2
Identities = 17/51 (33%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 332 NHITTLEETSKTFLPSLEELIAHHNNIT-VLDKDFHGLPSLCSADLSFNKI 381
N I ++++ +L +L EL N+ + D DFH LP L S L N++
Sbjct: 79 NSIVRVDQSELGYLANLTELDLSQNSFSDARDCDFHALPQLLSLHLEENQL 129
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.135 0.387
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,975,716
Number of Sequences: 224733
Number of extensions: 3037947
Number of successful extensions: 15451
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 599
Number of HSP's successfully gapped in prelim test: 183
Number of HSP's that attempted gapping in prelim test: 7910
Number of HSP's gapped (non-prelim): 4463
length of query: 562
length of database: 73,234,838
effective HSP length: 94
effective length of query: 468
effective length of database: 52,109,936
effective search space: 24387450048
effective search space used: 24387450048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)
- SilkBase 1999-2023 -